# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- 7tm_4 PF13853.1 EMC76724.1 - 3.8e-61 205.1 12.0 3.8e-61 205.1 8.3 1.6 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC76724.1 - 1.3e-34 119.4 15.0 1.6e-34 119.1 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC76724.1 - 0.003 16.7 12.8 0.0033 16.6 6.9 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Nramp PF01566.13 EMC76726.1 - 6.2e-13 48.2 6.3 2.5e-09 36.4 0.7 3.0 2 1 1 3 3 3 2 Natural resistance-associated macrophage protein BTB PF00651.26 EMC76727.1 - 3.7e-28 97.7 0.2 6.3e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.12 EMC76727.1 - 3.7e-13 49.5 2.5 8e-13 48.5 1.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EMC76727.1 - 9.7e-10 38.2 6.9 1.9e-09 37.3 4.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC76727.1 - 1.6e-05 24.6 8.0 3.2e-05 23.6 5.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF1199 PF06712.6 EMC76727.1 - 0.84 9.5 3.2 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Connexin PF00029.14 EMC76728.1 - 2.5e-50 169.0 0.2 5.9e-50 167.8 0.1 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC76728.1 - 8.1e-34 115.2 1.0 1.7e-33 114.2 0.7 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Tachystatin_A PF11406.3 EMC76729.1 - 0.54 10.1 2.0 0.52 10.2 0.1 1.9 2 0 0 2 2 2 0 Antimicrobial peptide tachystatin A Complex1_LYR PF05347.10 EMC76730.1 - 1.4e-20 72.8 0.5 1.8e-20 72.4 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC76730.1 - 2.9e-18 65.7 0.5 3.5e-18 65.5 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMC76730.1 - 1.4e-05 25.5 0.3 1.8e-05 25.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ETC_C1_NDUFA5 PF04716.9 EMC76730.1 - 0.1 12.1 0.0 0.85 9.1 0.0 1.9 2 0 0 2 2 2 0 ETC complex I subunit conserved region Ank PF00023.25 EMC76731.1 - 3.7e-52 171.6 23.1 2e-11 43.0 0.2 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.2 EMC76731.1 - 9.6e-52 173.2 15.4 2.5e-19 69.4 0.4 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC76731.1 - 2.4e-42 142.5 19.3 2.6e-10 40.5 0.1 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC76731.1 - 1.6e-40 136.2 26.9 9.9e-11 41.5 0.2 6.3 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC76731.1 - 6.6e-39 128.0 11.2 1.1e-06 28.3 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat XhlA PF10779.4 EMC76731.1 - 1.6 8.6 7.1 0.58 10.1 1.3 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Gtr1_RagA PF04670.7 EMC76732.1 - 1.8e-73 246.5 0.9 2.5e-73 246.0 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EMC76732.1 - 2.9e-07 29.9 0.0 4.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC76732.1 - 6.5e-06 25.4 0.1 1.5e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC76732.1 - 3.4e-05 24.3 0.0 0.00017 22.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EMC76732.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EMC76732.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EMC76732.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 EMC76733.1 - 2e-21 75.8 0.0 3.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC76733.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RWD domain Neur_chan_LBD PF02931.18 EMC76734.1 - 3.9e-55 186.3 0.7 6.7e-55 185.5 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC76734.1 - 8.4e-44 150.2 5.1 8.7e-38 130.5 0.6 3.1 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC76735.1 - 6.2e-55 185.6 0.7 9.2e-55 185.1 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC76735.1 - 1.1e-41 143.2 9.7 9.6e-37 127.1 0.7 2.8 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region DUF2365 PF10157.4 EMC76736.1 - 1.9e-20 73.2 0.0 2.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) KASH PF10541.4 EMC76736.1 - 0.033 14.0 0.7 0.051 13.4 0.5 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain PNRC PF15365.1 EMC76737.1 - 7.9e-21 73.8 0.6 7.9e-21 73.8 0.4 2.1 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Amelogenin PF02948.10 EMC76737.1 - 0.06 13.9 6.5 0.085 13.4 4.5 1.3 1 1 0 1 1 1 0 Amelogenin mRNA_cap_enzyme PF01331.14 EMC76738.1 - 5.1e-72 241.6 0.3 7.2e-72 241.1 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DSPc PF00782.15 EMC76738.1 - 1.8e-10 40.5 0.0 3.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.16 EMC76738.1 - 4.6e-07 29.4 0.0 9.5e-05 21.8 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase PF00102.22 EMC76738.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase mRNA_cap_C PF03919.10 EMC76738.1 - 0.0024 18.1 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Y_phosphatase3 PF13350.1 EMC76738.1 - 0.01 16.1 0.0 0.046 13.9 0.0 1.8 1 1 1 2 2 2 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EMC76738.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Filament PF00038.16 EMC76739.1 - 3.5e-23 82.5 4.8 4.1e-23 82.3 3.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein BRE1 PF08647.6 EMC76739.1 - 0.034 14.1 1.5 0.056 13.4 1.1 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF972 PF06156.8 EMC76739.1 - 0.11 12.9 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_27 PF13514.1 EMC76739.1 - 0.2 9.3 2.7 0.24 9.0 1.9 1.0 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 EMC76741.1 - 6.8e-104 347.6 39.5 8e-104 347.4 27.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC76741.1 - 2.7e-06 27.1 38.5 0.00022 20.9 3.2 3.5 3 1 0 3 3 3 3 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EMC76741.1 - 5.8e-06 24.3 29.6 5.8e-06 24.3 20.5 2.0 1 1 1 2 2 2 1 Myosin tail ATG16 PF08614.6 EMC76741.1 - 0.00037 20.3 31.7 0.065 13.0 6.0 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EMC76741.1 - 0.028 13.5 4.8 1.2 8.2 0.3 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CENP-Q PF13094.1 EMC76741.1 - 0.038 14.0 33.0 0.58 10.1 3.9 3.2 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 EMC76741.1 - 0.04 13.7 17.5 1.5 8.6 1.1 4.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EMC76741.1 - 0.083 12.7 31.3 0.24 11.2 0.9 3.2 3 0 0 3 3 3 0 Tropomyosin like AAA_13 PF13166.1 EMC76741.1 - 0.089 11.2 26.0 0.042 12.3 15.6 1.9 1 1 0 1 1 1 0 AAA domain FUSC PF04632.7 EMC76741.1 - 0.31 9.4 6.5 0.17 10.2 3.0 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family WEMBL PF05701.6 EMC76741.1 - 0.45 8.9 28.9 0.59 8.5 10.8 2.4 1 1 0 2 2 2 0 Weak chloroplast movement under blue light Fib_alpha PF08702.5 EMC76741.1 - 0.73 9.9 28.6 0.035 14.2 3.6 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EMC76741.1 - 0.78 9.5 33.7 0.3 10.9 7.9 3.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 EMC76741.1 - 1.3 7.3 27.0 0.27 9.6 4.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF883 PF05957.8 EMC76741.1 - 6.7 7.1 18.7 9.1 6.7 0.7 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Filament PF00038.16 EMC76742.1 - 2e-100 336.3 36.5 2.3e-100 336.0 25.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC76742.1 - 1.1e-06 28.3 29.5 0.0016 18.1 0.5 3.5 4 0 0 4 4 4 2 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 EMC76742.1 - 0.0011 18.7 7.0 0.51 10.1 1.4 3.6 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 EMC76742.1 - 0.0028 17.4 26.7 0.077 12.8 3.0 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 EMC76742.1 - 0.014 13.8 19.5 0.034 12.6 13.5 1.7 1 1 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 EMC76742.1 - 0.017 12.9 31.6 0.054 11.2 21.9 1.8 1 1 0 1 1 1 0 Myosin tail bZIP_1 PF00170.16 EMC76742.1 - 0.019 14.9 1.0 0.019 14.9 0.7 5.0 5 0 0 5 5 5 0 bZIP transcription factor Reo_sigmaC PF04582.7 EMC76742.1 - 0.024 13.8 1.2 9.1 5.3 0.5 2.8 1 1 1 3 3 3 0 Reovirus sigma C capsid protein CENP-Q PF13094.1 EMC76742.1 - 0.037 14.0 27.3 0.38 10.7 2.6 2.7 2 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 EMC76742.1 - 0.038 13.8 31.8 0.18 11.6 1.5 3.7 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EMC76742.1 - 0.18 11.6 34.1 0.14 12.0 10.6 3.1 2 1 1 3 3 3 0 Tropomyosin like ADIP PF11559.3 EMC76742.1 - 0.24 11.2 28.2 0.45 10.4 3.3 3.0 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding BicD PF09730.4 EMC76742.1 - 0.32 9.2 27.4 0.55 8.5 2.8 2.2 1 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF883 PF05957.8 EMC76742.1 - 0.37 11.2 16.9 3.9 7.9 3.7 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.7 EMC76742.1 - 0.91 7.8 5.7 0.8 8.0 2.8 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Fib_alpha PF08702.5 EMC76742.1 - 1 9.5 23.8 0.041 14.0 0.7 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 EMC76742.1 - 1 9.7 32.1 4.2 7.7 6.4 5.0 2 2 3 5 5 5 0 Protein of unknown function (DUF972) Spc7 PF08317.6 EMC76742.1 - 1.1 7.8 29.7 0.042 12.5 5.3 3.1 1 1 1 3 3 3 0 Spc7 kinetochore protein TMCO5 PF14992.1 EMC76742.1 - 1.4 7.9 26.8 0.37 9.8 7.3 2.2 1 1 1 2 2 2 0 TMCO5 family CHDCT2 PF08074.6 EMC76742.1 - 1.6 8.4 7.6 1.6 8.4 0.1 2.6 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain Transposase_22 PF02994.9 EMC76742.1 - 2.2 6.6 20.6 0.44 8.9 7.3 2.2 1 1 0 2 2 2 0 L1 transposable element DUF342 PF03961.8 EMC76742.1 - 3.9 5.7 24.7 0.53 8.6 2.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF342) HALZ PF02183.13 EMC76742.1 - 4.2 7.1 17.9 0.26 11.0 0.4 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper BLOC1_2 PF10046.4 EMC76742.1 - 4.2 7.5 16.8 4.7 7.4 1.4 4.5 3 3 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CALCOCO1 PF07888.6 EMC76742.1 - 4.4 5.4 30.1 12 4.0 20.9 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.16 EMC76743.1 - 1.6e-80 270.8 35.1 1.9e-80 270.6 24.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 EMC76743.1 - 0.0012 18.4 12.3 0.0012 18.4 8.5 2.8 2 1 0 2 2 2 1 IncA protein FlaC_arch PF05377.6 EMC76743.1 - 0.0017 18.2 5.8 0.35 10.7 0.2 4.5 5 1 0 5 5 5 1 Flagella accessory protein C (FlaC) DivIC PF04977.10 EMC76743.1 - 0.002 17.5 2.0 0.002 17.5 1.4 5.7 3 2 3 6 6 6 1 Septum formation initiator CENP-F_leu_zip PF10473.4 EMC76743.1 - 0.022 14.6 34.1 0.23 11.2 7.9 3.9 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EMC76743.1 - 0.024 14.9 23.5 0.38 11.1 0.3 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 EMC76743.1 - 0.087 11.7 17.1 0.012 14.5 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 EMC76743.1 - 0.14 10.5 17.7 0.035 12.5 7.9 2.3 1 1 1 2 2 2 0 AAA domain Transposase_22 PF02994.9 EMC76743.1 - 0.22 9.9 15.3 0.11 10.9 1.0 2.3 1 1 1 2 2 2 0 L1 transposable element Hemerythrin PF01814.18 EMC76743.1 - 0.31 11.1 18.8 0.66 10.1 2.0 4.0 1 1 3 4 4 4 0 Hemerythrin HHE cation binding domain LXG PF04740.7 EMC76743.1 - 0.34 10.6 8.9 1.1 9.0 0.2 3.3 3 1 0 3 3 3 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.14 EMC76743.1 - 0.37 8.4 33.5 3.2 5.3 23.4 2.2 1 1 0 1 1 1 0 Myosin tail TPR_MLP1_2 PF07926.7 EMC76743.1 - 0.55 9.9 29.2 1.4 8.7 4.8 3.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 EMC76743.1 - 0.75 9.9 14.4 0.074 13.2 1.0 3.4 3 1 0 3 3 3 0 Syntaxin WXG100 PF06013.7 EMC76743.1 - 0.93 9.5 15.7 1.5 8.8 0.1 3.8 3 1 1 4 4 4 0 Proteins of 100 residues with WXG NPV_P10 PF05531.7 EMC76743.1 - 1 9.6 8.1 56 4.0 0.1 4.5 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.1 EMC76743.1 - 1.1 9.2 10.9 0.22 11.5 1.4 3.1 2 1 0 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.5 EMC76743.1 - 1.4 9.0 15.7 1.7 8.7 0.4 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MIF4G_like_2 PF09090.6 EMC76743.1 - 2.3 7.3 7.7 0.54 9.4 0.3 2.3 2 0 0 2 2 2 0 MIF4G like DUF342 PF03961.8 EMC76743.1 - 2.6 6.3 15.1 0.43 8.9 1.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 EMC76743.1 - 2.7 5.2 30.7 11 3.1 21.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.1 EMC76743.1 - 4.6 6.3 27.5 0.1 11.7 3.3 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DNA_repr_REX1B PF14966.1 EMC76743.1 - 5.6 7.4 9.8 13 6.2 0.2 3.3 2 1 1 3 3 3 0 DNA repair REX1-B Seryl_tRNA_N PF02403.17 EMC76743.1 - 8.1 6.5 22.5 2.1 8.3 1.7 3.4 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 EMC76743.1 - 9.9 6.0 27.7 1.4 8.7 4.9 3.0 2 1 0 2 2 2 0 Tropomyosin like Filament PF00038.16 EMC76744.1 - 3.4e-86 289.5 28.3 3.8e-86 289.3 19.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 EMC76744.1 - 0.00034 20.4 7.9 0.00034 20.4 5.5 3.2 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 cwf21 PF08312.7 EMC76744.1 - 0.0025 17.6 0.2 0.065 13.0 0.0 3.2 3 1 0 3 3 2 1 cwf21 domain Reo_sigmaC PF04582.7 EMC76744.1 - 0.015 14.5 1.8 0.068 12.3 0.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FliJ PF02050.11 EMC76744.1 - 0.022 14.8 3.8 0.022 14.8 2.7 3.5 3 1 1 4 4 4 0 Flagellar FliJ protein Baculo_PEP_C PF04513.7 EMC76744.1 - 0.052 13.3 0.5 0.052 13.3 0.3 2.8 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 EMC76744.1 - 0.068 12.9 20.5 0.091 12.5 7.0 3.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EMC76744.1 - 0.084 10.5 24.5 0.096 10.3 15.1 2.1 1 1 0 1 1 1 0 Myosin tail gpW PF02831.10 EMC76744.1 - 0.26 10.8 1.2 17 5.0 0.0 3.2 1 1 0 2 2 2 0 gpW AAA_13 PF13166.1 EMC76744.1 - 0.6 8.5 16.8 1.2 7.5 11.7 1.6 1 1 0 1 1 1 0 AAA domain DUF883 PF05957.8 EMC76744.1 - 0.62 10.4 6.2 15 6.0 1.2 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) WEMBL PF05701.6 EMC76744.1 - 0.67 8.3 19.1 0.17 10.2 7.5 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF4407 PF14362.1 EMC76744.1 - 1.1 8.1 7.4 0.62 8.9 3.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.7 EMC76744.1 - 1.5 8.7 11.7 7.8 6.5 0.0 5.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Tropomyosin PF00261.15 EMC76744.1 - 3.7 6.5 22.1 0.039 13.0 4.9 3.2 2 1 1 4 4 4 0 Tropomyosin DUF948 PF06103.6 EMC76744.1 - 6.1 6.7 6.3 20 5.1 1.1 3.6 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) ACCA PF03255.9 EMC76744.1 - 7.1 6.1 9.3 13 5.3 0.8 3.5 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MutS_III PF05192.13 EMC76744.1 - 9.8 5.9 8.7 2.3 7.9 2.2 2.1 2 0 0 2 2 2 0 MutS domain III Filament PF00038.16 EMC76745.1 - 1.2e-108 363.3 28.5 1.4e-108 363.1 19.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein Vps53_N PF04100.7 EMC76745.1 - 0.0015 17.4 2.3 0.0036 16.1 1.6 1.6 1 0 0 1 1 1 1 Vps53-like, N-terminal COG5 PF10392.4 EMC76745.1 - 0.0034 17.3 1.4 0.0088 16.0 1.0 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ATG16 PF08614.6 EMC76745.1 - 0.0065 16.3 21.7 0.019 14.7 2.9 3.0 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EMC76745.1 - 0.011 15.6 21.5 0.16 11.8 6.6 2.6 2 1 0 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.7 EMC76745.1 - 0.011 15.5 0.7 0.011 15.5 0.5 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 EMC76745.1 - 0.047 13.5 18.6 0.5 10.2 4.3 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EMC76745.1 - 0.28 9.6 19.5 0.022 13.2 9.3 1.9 1 1 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 EMC76745.1 - 0.37 10.5 29.3 0.021 14.5 1.4 3.5 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3618 PF12277.3 EMC76745.1 - 0.99 9.4 5.1 4.9 7.2 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) TraC PF07820.7 EMC76745.1 - 2 8.6 8.8 6.8 6.9 3.2 2.8 2 0 0 2 2 2 0 TraC-like protein Spc7 PF08317.6 EMC76745.1 - 2.2 6.8 20.5 0.069 11.7 5.7 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2935 PF11155.3 EMC76745.1 - 2.6 8.1 8.6 0.31 11.1 0.1 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) NPV_P10 PF05531.7 EMC76745.1 - 4.3 7.6 10.2 2.5 8.4 0.3 3.6 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EMC76745.1 - 5.9 6.9 14.8 6.4 6.8 0.1 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Filament PF00038.16 EMC76747.1 - 1.5e-111 372.8 35.4 1.7e-111 372.6 24.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC76747.1 - 0.00012 21.7 29.7 0.00043 20.0 0.7 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EMC76747.1 - 0.00079 17.2 4.4 0.00079 17.2 3.0 2.6 1 1 0 2 2 2 2 Myosin tail AAA_13 PF13166.1 EMC76747.1 - 0.0016 17.0 15.9 0.0016 17.0 11.0 2.0 1 1 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 EMC76747.1 - 0.002 18.0 27.4 0.017 14.9 5.8 3.7 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EMC76747.1 - 0.005 16.4 27.0 0.013 15.1 5.4 3.3 2 1 1 3 3 3 2 IncA protein Baculo_PEP_C PF04513.7 EMC76747.1 - 0.0077 16.0 0.6 0.0077 16.0 0.4 4.5 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EMC76747.1 - 0.019 14.1 6.4 0.41 9.7 0.3 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DED PF01335.16 EMC76747.1 - 0.042 13.9 3.1 0.91 9.6 0.1 2.6 2 0 0 2 2 2 0 Death effector domain Tropomyosin_1 PF12718.2 EMC76747.1 - 0.073 12.9 29.7 0.4 10.5 8.1 3.6 2 1 1 4 4 4 0 Tropomyosin like Fib_alpha PF08702.5 EMC76747.1 - 0.09 12.8 20.2 0.058 13.5 0.7 3.6 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family ACCA PF03255.9 EMC76747.1 - 0.1 12.1 14.3 0.51 9.8 0.8 3.4 2 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ADIP PF11559.3 EMC76747.1 - 0.29 11.0 28.7 0.38 10.6 5.9 3.9 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EMC76747.1 - 0.38 9.3 29.7 0.045 12.4 6.7 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein PRESAN PF09687.5 EMC76747.1 - 0.48 10.4 5.8 3.4 7.7 0.4 2.8 2 1 1 3 3 3 0 Plasmodium RESA N-terminal Jnk-SapK_ap_N PF09744.4 EMC76747.1 - 2.4 8.1 28.6 0.76 9.7 2.0 3.9 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 DUF948 PF06103.6 EMC76747.1 - 3.8 7.4 12.6 2.8 7.8 0.8 4.4 3 3 2 5 5 5 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.6 EMC76747.1 - 4.1 7.4 15.8 0.079 12.9 3.6 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Kinesin-relat_1 PF12711.2 EMC76747.1 - 4.7 7.6 18.8 16 5.9 0.1 4.8 3 2 2 5 5 5 0 Kinesin motor DUF1664 PF07889.7 EMC76747.1 - 5.3 6.8 16.0 6 6.6 0.5 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EMC76747.1 - 5.9 6.8 14.7 3.4 7.6 0.5 5.2 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF2580 PF10824.3 EMC76747.1 - 8.6 6.7 9.7 1.8 8.9 1.4 2.9 4 0 0 4 4 2 0 Protein of unknown function (DUF2580) Filament PF00038.16 EMC76748.1 - 5.3e-109 364.4 33.8 6.3e-109 364.2 23.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC76748.1 - 9e-06 25.4 37.4 0.00036 20.2 5.7 3.9 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EMC76748.1 - 0.00025 20.9 4.9 0.00025 20.9 3.4 3.7 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EMC76748.1 - 0.00055 19.2 9.8 0.0027 16.9 0.8 2.4 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EMC76748.1 - 0.0012 18.6 9.2 0.0012 18.6 6.4 3.5 2 1 1 3 3 3 1 Tropomyosin like IncA PF04156.9 EMC76748.1 - 0.0014 18.2 35.4 0.12 12.0 7.7 3.5 1 1 1 2 2 2 1 IncA protein Phage_GP20 PF06810.6 EMC76748.1 - 0.0015 18.0 3.9 0.0015 18.0 2.7 3.7 2 1 2 4 4 4 1 Phage minor structural protein GP20 ADIP PF11559.3 EMC76748.1 - 0.0023 17.8 29.2 0.025 14.4 4.7 4.2 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 EMC76748.1 - 0.003 16.5 21.3 0.02 13.8 2.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.14 EMC76748.1 - 0.0073 14.0 37.4 0.0045 14.7 21.1 2.7 1 1 0 2 2 2 1 Myosin tail AAA_13 PF13166.1 EMC76748.1 - 0.011 14.2 26.8 0.0051 15.3 13.0 2.6 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 EMC76748.1 - 0.06 12.5 32.2 0.14 11.2 4.9 3.4 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 EMC76748.1 - 0.13 11.8 28.9 0.017 14.7 4.2 3.8 1 1 3 4 4 4 0 Mnd1 family FlaC_arch PF05377.6 EMC76748.1 - 0.28 11.1 13.8 0.87 9.5 0.0 5.4 6 1 0 6 6 5 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EMC76748.1 - 0.3 11.4 26.9 3.4 8.0 1.0 5.1 1 1 3 5 5 5 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EMC76748.1 - 0.32 11.1 19.7 0.46 10.6 1.1 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family BRE1 PF08647.6 EMC76748.1 - 0.36 10.8 22.9 0.15 12.0 1.3 4.2 2 2 3 5 5 5 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.4 EMC76748.1 - 0.37 9.6 25.5 0.5 9.2 2.5 2.7 1 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 EMC76748.1 - 0.44 7.8 30.7 0.24 8.6 17.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.3 EMC76748.1 - 0.45 10.3 32.6 0.027 14.2 2.2 5.4 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Shugoshin_N PF07558.6 EMC76748.1 - 0.49 10.1 7.4 2.1 8.1 0.2 3.9 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region DUF342 PF03961.8 EMC76748.1 - 0.6 8.4 20.2 0.39 9.0 2.6 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF948 PF06103.6 EMC76748.1 - 0.7 9.7 8.8 0.93 9.3 0.3 4.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 EMC76748.1 - 1.7 8.4 17.8 0.45 10.3 0.1 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EMC76748.1 - 1.9 7.1 30.6 0.058 12.0 5.5 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EMC76748.1 - 2.5 8.1 28.8 0.15 12.0 4.6 3.7 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Transposase_22 PF02994.9 EMC76748.1 - 3.5 6.0 16.4 0.037 12.5 2.0 2.5 1 1 2 3 3 3 0 L1 transposable element Baculo_PEP_C PF04513.7 EMC76748.1 - 4.1 7.2 20.4 0.65 9.8 0.8 4.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.3 EMC76748.1 - 8.2 6.1 33.6 0.57 9.9 0.8 5.4 1 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding Vps51 PF08700.6 EMC76748.1 - 8.8 6.2 12.0 0.85 9.4 0.1 3.9 4 1 1 5 5 4 0 Vps51/Vps67 Bin3 PF06859.7 EMC76749.1 - 4.6e-12 45.9 0.0 6.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.7 EMC76749.1 - 0.0022 18.4 0.0 0.037 14.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain HHH_8 PF14716.1 EMC76749.1 - 0.056 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain MIP PF00230.15 EMC76750.1 - 3.8e-73 245.7 18.8 4.6e-73 245.4 13.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Polysacc_synt PF01943.12 EMC76750.1 - 0.98 8.6 15.3 2.8 7.1 8.2 2.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Hormone_2 PF00123.15 EMC76751.1 - 1.4e-11 44.0 0.5 1.1e-10 41.0 0.1 2.1 2 0 0 2 2 2 1 Peptide hormone HCO3_cotransp PF00955.16 EMC76752.1 - 2.4e-241 801.8 7.6 3e-241 801.5 5.3 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 EMC76752.1 - 5.1e-98 327.6 0.0 1e-97 326.7 0.0 1.5 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DAZAP2 PF11029.3 EMC76754.1 - 1.5e-16 61.0 0.8 1.6e-16 60.9 0.5 1.0 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) CytB6-F_Fe-S PF08802.5 EMC76754.1 - 9.9 6.2 13.7 0.11 12.5 3.0 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Collagen PF01391.13 EMC76755.1 - 6.4e-91 297.8 344.5 4.5e-08 32.5 16.8 12.5 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) DnaJ PF00226.26 EMC76757.1 - 1.1e-28 98.7 2.5 1.9e-28 97.9 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMC76757.1 - 3.1e-23 81.4 1.0 4.2e-18 65.0 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMC76757.1 - 3e-13 49.6 20.7 5.6e-13 48.7 14.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EMC76757.1 - 0.027 14.1 8.4 0.85 9.3 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family WD40 PF00400.27 EMC76758.1 - 5.4e-47 156.0 12.9 5.9e-11 41.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC76758.1 - 2.6e-10 39.0 1.3 1.7e-06 26.4 0.5 3.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC76758.1 - 9e-05 21.3 1.0 0.11 11.2 0.7 3.6 2 1 1 3 3 3 1 Nup133 N terminal like Hira PF07569.6 EMC76758.1 - 0.00035 19.8 0.2 1.3 8.1 0.0 3.8 3 1 1 4 4 4 1 TUP1-like enhancer of split LisH PF08513.6 EMC76758.1 - 0.015 15.0 0.1 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 LisH PD40 PF07676.7 EMC76758.1 - 0.078 12.6 0.0 3.6 7.3 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CSD PF00313.17 EMC76759.1 - 4.3e-10 39.2 0.0 1.5e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain Glyco_transf_7N PF13733.1 EMC76760.1 - 3.1e-48 162.6 0.1 4.5e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 EMC76760.1 - 9.9e-34 114.6 0.5 1.8e-33 113.8 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC76760.1 - 1e-06 28.0 0.2 0.00049 19.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Kazal_1 PF00050.16 EMC76761.1 - 5.8e-17 61.4 5.0 7.1e-16 57.9 0.7 2.0 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC76761.1 - 1.4e-12 47.2 0.5 1.4e-12 47.2 0.3 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Prok-RING_1 PF14446.1 EMC76761.1 - 2.8 7.7 5.4 3.5 7.4 0.4 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Trypan_PARP PF05887.6 EMC76762.1 - 0.015 15.1 7.4 0.027 14.3 5.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spore_YabQ PF09578.5 EMC76763.1 - 0.022 14.6 0.2 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) Tropomyosin_1 PF12718.2 EMC76763.1 - 1.6 8.5 55.1 2.9 7.7 24.3 3.5 1 1 1 2 2 2 0 Tropomyosin like AAA_13 PF13166.1 EMC76763.1 - 3.8 5.8 39.9 17 3.7 27.6 1.9 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EMC76763.1 - 9.4 3.4 48.2 13 2.8 33.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IFT57 PF10498.4 EMC76764.1 - 2.4e-100 335.7 4.3 2.7e-100 335.6 3.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Bacillus_HBL PF05791.6 EMC76764.1 - 0.027 13.8 5.4 0.083 12.2 0.1 2.3 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Ribonuc_L-PSP PF01042.16 EMC76764.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP Prominin PF05478.6 EMC76764.1 - 0.056 10.9 1.7 0.065 10.7 1.2 1.1 1 0 0 1 1 1 0 Prominin Halogen_Hydrol PF10112.4 EMC76764.1 - 0.086 12.2 2.3 0.18 11.2 0.2 2.3 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YscJ_FliF PF01514.12 EMC76764.1 - 0.11 11.6 1.0 5 6.2 0.0 2.2 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family V-set_CD47 PF08204.6 EMC76765.1 - 1.4e-34 118.6 0.1 2.5e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain CD47 PF04549.9 EMC76765.1 - 4.4e-32 111.2 12.8 5.8e-32 110.8 8.8 1.1 1 0 0 1 1 1 1 CD47 transmembrane region I-set PF07679.11 EMC76765.1 - 0.029 14.2 0.1 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain C1-set PF07654.10 EMC76765.1 - 0.092 12.7 1.2 0.49 10.4 0.8 2.1 1 1 0 1 1 1 0 Immunoglobulin C1-set domain XK-related PF09815.4 EMC76766.1 - 1.1e-97 327.0 29.0 1.3e-97 326.8 20.1 1.0 1 0 0 1 1 1 1 XK-related protein Lactamase_B PF00753.22 EMC76767.1 - 4e-25 88.5 1.2 5e-25 88.2 0.9 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC76767.1 - 7.7e-05 22.3 0.1 0.00016 21.2 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC76767.1 - 0.084 12.5 0.1 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TRAM1 PF08390.6 EMC76768.1 - 1.5e-24 85.2 1.4 4.1e-24 83.8 0.9 1.8 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 EMC76768.1 - 5.9e-23 81.4 18.4 9.5e-23 80.7 12.7 1.3 1 0 0 1 1 1 1 TLC domain DUF3112 PF11309.3 EMC76768.1 - 0.0025 17.6 8.4 0.048 13.4 0.8 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF3112) zf-H2C2_2 PF13465.1 EMC76769.1 - 4e-27 93.1 53.3 4.5e-10 39.3 0.4 6.7 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC76769.1 - 1.2e-20 72.5 55.9 9.4e-07 28.8 2.5 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC76769.1 - 9.9e-18 63.1 48.4 3.2e-05 23.9 0.8 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC76769.1 - 1.2e-10 40.8 33.9 0.0018 18.1 0.5 7.0 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC76769.1 - 7.1e-09 35.5 30.4 0.0038 17.3 0.6 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding SET PF00856.23 EMC76769.1 - 2.8e-06 27.7 0.1 3.1e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 SET domain zf-C2HC_2 PF13913.1 EMC76769.1 - 4e-06 26.3 26.2 0.007 16.0 1.8 6.5 6 0 0 6 6 6 3 zinc-finger of a C2HC-type zf-met PF12874.2 EMC76769.1 - 0.0004 20.4 34.1 0.14 12.4 1.8 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC76769.1 - 0.0068 16.4 32.9 0.26 11.3 1.4 5.7 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EMC76769.1 - 0.0083 15.8 40.2 0.44 10.3 0.4 6.4 2 2 4 6 6 6 3 BED zinc finger zf-Di19 PF05605.7 EMC76769.1 - 0.038 14.1 34.3 0.76 9.9 0.1 3.9 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 EMC76769.1 - 0.042 13.5 25.6 0.1 12.3 1.1 5.0 3 2 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PyrI_C PF02748.10 EMC76769.1 - 0.15 11.5 0.1 0.15 11.5 0.1 5.7 4 2 2 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PRP21_like_P PF12230.3 EMC76769.1 - 1.6 8.1 5.0 9.5 5.6 0.3 2.5 2 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Rad50_zn_hook PF04423.9 EMC76769.1 - 2.5 7.6 13.4 5.2 6.6 0.6 3.7 3 1 1 4 4 4 0 Rad50 zinc hook motif XPA_N PF01286.13 EMC76769.1 - 3.2 7.5 17.8 3.5 7.3 0.3 5.1 5 0 0 5 5 5 0 XPA protein N-terminal YhfH PF14149.1 EMC76769.1 - 3.9 7.3 17.4 7.3 6.4 0.8 4.6 3 1 1 4 4 4 0 YhfH-like protein zf-FPG_IleRS PF06827.9 EMC76769.1 - 4 7.1 13.7 2.3 7.9 0.0 4.8 5 0 0 5 5 4 0 Zinc finger found in FPG and IleRS OATP PF03137.15 EMC76770.1 - 5e-159 529.8 12.0 6.2e-159 529.5 8.3 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EMC76770.1 - 1.1e-26 93.4 25.0 1.9e-26 92.6 10.6 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.10 EMC76770.1 - 1.2e-09 37.9 9.3 2.7e-09 36.7 4.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC76770.1 - 8.7e-05 22.4 9.5 0.00024 21.0 6.6 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Folate_carrier PF01770.13 EMC76770.1 - 0.00065 18.3 0.0 0.0012 17.4 0.0 1.4 1 0 0 1 1 1 1 Reduced folate carrier S1FA PF04689.8 EMC76770.1 - 0.056 13.3 0.6 0.21 11.5 0.4 2.0 1 0 0 1 1 1 0 DNA binding protein S1FA DUF3740 PF12548.3 EMC76771.1 - 9.9e-52 175.0 0.8 9.9e-52 175.0 0.6 2.4 3 0 0 3 3 3 1 Sulfatase protein Sulfatase PF00884.18 EMC76771.1 - 5e-48 163.8 0.7 5e-48 163.8 0.5 1.7 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EMC76771.1 - 0.0052 16.1 7.4 0.0069 15.7 2.3 2.4 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase PXT1 PF15214.1 EMC76776.1 - 0.12 12.6 3.5 9.9 6.5 0.1 2.7 3 0 0 3 3 3 0 Peroxisomal testis-specific protein 1 HSF_DNA-bind PF00447.12 EMC76779.1 - 7.8e-29 99.8 1.3 1.1e-28 99.4 0.9 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2365 PF10157.4 EMC76779.1 - 0.037 13.9 0.1 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) TEX33 PF15400.1 EMC76780.1 - 3.8e-34 118.0 0.2 4.1e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family Rhodanese PF00581.15 EMC76781.1 - 4e-30 104.4 0.0 6.6e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Toxin_65 PF15543.1 EMC76781.1 - 0.054 13.1 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 65 Rhodanese PF00581.15 EMC76782.1 - 2.1e-32 111.7 0.0 3.4e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain B12D PF06522.6 EMC76782.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BTB_2 PF02214.17 EMC76783.1 - 1.5e-22 79.6 0.0 2.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EMC76783.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain NRDE PF05742.7 EMC76783.1 - 0.11 11.7 0.2 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 NRDE protein eIF_4EBP PF05456.6 EMC76783.1 - 2.7 7.7 5.0 2.1 8.0 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) fn3 PF00041.16 EMC76784.1 - 1.3e-07 31.6 1.2 2.3e-07 30.8 0.8 1.5 1 0 0 1 1 1 1 Fibronectin type III domain DUF3943 PF13084.1 EMC76784.1 - 0.026 14.0 0.2 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) C1q PF00386.16 EMC76785.1 - 1.9e-33 115.1 1.4 2.3e-33 114.8 0.9 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC76785.1 - 8.5e-09 34.8 15.2 1.2e-08 34.3 10.5 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.16 EMC76786.1 - 7.1e-66 221.9 20.3 7.1e-66 221.9 14.1 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC76786.1 - 1.9e-11 43.6 12.8 2.4e-11 43.2 8.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC76786.1 - 7.4e-07 28.5 9.6 1e-06 28.1 6.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 EMC76786.1 - 6.8e-06 25.4 5.3 6.8e-06 25.4 3.7 2.0 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 EMC76786.1 - 0.00016 20.9 12.3 0.016 14.3 8.5 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.10 EMC76786.1 - 0.00055 19.7 1.7 0.00055 19.7 1.2 2.7 2 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa TAS2R PF05296.8 EMC76786.1 - 0.073 11.9 12.3 0.29 9.9 8.5 1.8 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) DUF2028 PF09667.5 EMC76786.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) Dicty_CAR PF05462.6 EMC76786.1 - 3 6.6 16.9 6.6 5.5 11.7 1.6 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Ras PF00071.17 EMC76787.1 - 5.1e-54 182.0 0.0 5.8e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC76787.1 - 2.3e-16 60.3 0.0 3.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC76787.1 - 2e-07 30.4 0.0 3.4e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC76787.1 - 0.0035 16.8 0.0 0.034 13.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Sec7 PF01369.15 EMC76788.1 - 1.9e-64 216.8 0.0 3.1e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EMC76788.1 - 4.5e-23 81.4 0.0 7.5e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC76788.1 - 2.9e-07 30.6 0.0 7.2e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Syntaxin-6_N PF09177.6 EMC76788.1 - 0.0036 17.6 1.5 1.8 9.0 0.0 2.7 2 0 0 2 2 2 2 Syntaxin 6, N-terminal PH_6 PF15406.1 EMC76788.1 - 0.0052 16.8 0.0 0.33 11.0 0.0 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EMC76788.1 - 0.021 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Laminin_I PF06008.9 EMC76788.1 - 0.032 13.5 1.0 0.049 12.9 0.7 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF2205 PF10224.4 EMC76788.1 - 0.39 10.3 2.9 0.72 9.4 2.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) LRR_8 PF13855.1 EMC76789.1 - 2.9e-21 74.9 10.3 1.3e-15 56.8 0.6 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC76789.1 - 2.1e-08 33.5 13.0 0.00091 18.7 0.1 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC76789.1 - 3.2e-07 30.1 1.2 9.5e-07 28.5 0.4 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC76789.1 - 0.0048 16.7 14.6 2.3 8.5 0.4 5.5 6 0 0 6 6 6 2 Leucine Rich Repeat Herpes_gE PF02480.11 EMC76789.1 - 0.0086 14.3 0.3 0.015 13.6 0.2 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E fn3 PF00041.16 EMC76789.1 - 0.0088 16.1 0.2 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LRR_6 PF13516.1 EMC76789.1 - 0.013 15.4 11.5 2.1 8.6 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeat DUF2816 PF10992.3 EMC76789.1 - 0.052 13.1 0.3 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2816) CARD PF00619.16 EMC76790.1 - 2.9e-20 71.8 1.7 5.6e-20 70.9 0.0 2.5 2 0 0 2 2 2 1 Caspase recruitment domain Guanylate_kin PF00625.16 EMC76790.1 - 0.0055 16.1 0.0 0.0055 16.1 0.0 2.0 2 0 0 2 2 2 1 Guanylate kinase BORG_CEP PF14957.1 EMC76791.1 - 4.1e-13 50.3 10.2 1e-07 32.9 1.4 3.3 3 1 1 4 4 4 2 Cdc42 effector PBD PF00786.23 EMC76791.1 - 7e-07 29.5 0.8 7e-07 29.5 0.6 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Gal-bind_lectin PF00337.17 EMC76792.1 - 2e-34 117.7 0.2 2.2e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin tRNA_anti-codon PF01336.20 EMC76792.1 - 0.03 14.1 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain VHS PF00790.14 EMC76793.1 - 1.4e-36 125.2 1.9 6.6e-36 123.0 0.0 2.3 2 1 1 3 3 3 1 VHS domain GAT PF03127.9 EMC76793.1 - 1.2e-34 118.3 4.4 1.2e-34 118.3 3.0 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EMC76793.1 - 8.9e-28 96.9 0.4 2.7e-27 95.3 0.1 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF1313 PF07011.6 EMC76793.1 - 0.00084 18.9 3.2 0.04 13.5 0.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1313) Ferritin PF00210.19 EMC76793.1 - 0.021 14.5 1.9 0.1 12.3 1.1 2.0 2 0 0 2 2 2 0 Ferritin-like domain MCPsignal PF00015.16 EMC76793.1 - 0.11 12.0 0.8 0.18 11.3 0.5 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2877 PF11392.3 EMC76793.1 - 0.23 11.7 0.3 3 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) SEN1_N PF12726.2 EMC76793.1 - 0.32 8.9 1.8 3 5.7 0.3 2.0 2 0 0 2 2 2 0 SEN1 N terminal Fib_alpha PF08702.5 EMC76793.1 - 0.69 10.0 5.9 1.5 8.9 4.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RhoGAP PF00620.22 EMC76794.1 - 1e-43 148.5 0.1 2.3e-43 147.4 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.13 EMC76794.1 - 3.9e-23 82.1 3.3 6.3e-23 81.4 2.3 1.3 1 0 0 1 1 1 1 BAR domain Hydrolase_like PF13242.1 EMC76794.1 - 3.2e-19 68.4 0.0 5.9e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EMC76794.1 - 3.9e-06 27.1 0.0 8e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC76794.1 - 9.4e-06 26.1 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EMC76794.1 - 0.04 13.2 0.0 0.086 12.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Gal-bind_lectin PF00337.17 EMC76795.1 - 4.6e-30 103.6 0.1 5.4e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin 7tm_1 PF00001.16 EMC76796.1 - 6.5e-32 110.6 10.0 8.2e-32 110.3 6.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tmemb_185A PF10269.4 EMC76796.1 - 0.13 11.8 0.3 0.13 11.8 0.2 2.5 2 1 0 2 2 2 0 Transmembrane Fragile-X-F protein ArfGap PF01412.13 EMC76797.1 - 4.1e-37 126.5 0.2 8.6e-37 125.4 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EMC76797.1 - 3.1e-17 62.6 0.8 4.9e-08 33.1 0.3 3.0 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC76797.1 - 1.3e-10 41.4 0.7 6.8e-07 29.5 0.2 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EMC76797.1 - 2.6e-06 27.4 1.1 0.023 14.7 0.0 2.8 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 EMC76797.1 - 6.2e-05 22.8 0.9 0.063 13.1 0.0 3.1 3 1 0 3 3 3 2 PH domain Nop25 PF09805.4 EMC76798.1 - 1.6e-06 28.2 3.6 1.6e-06 28.2 2.5 2.2 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Hepatitis_core PF00906.15 EMC76798.1 - 0.41 10.2 6.1 0.66 9.6 4.2 1.3 1 0 0 1 1 1 0 Hepatitis core antigen Linker_histone PF00538.14 EMC76799.1 - 3.1e-14 52.8 0.5 6.1e-14 51.8 0.4 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Pol_alpha_B_N PF08418.5 EMC76799.1 - 0.03 13.8 7.2 0.03 13.8 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_DNAp_acc PF04929.7 EMC76799.1 - 0.3 10.0 11.3 0.34 9.8 7.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF1777 PF08648.7 EMC76799.1 - 2.4 7.8 17.0 2.9 7.5 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DDHD PF02862.12 EMC76799.1 - 3.5 7.3 6.2 3.2 7.4 4.3 1.1 1 0 0 1 1 1 0 DDHD domain Aminotran_1_2 PF00155.16 EMC76800.1 - 4.5e-72 242.9 0.0 5.7e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMC76800.1 - 7.6e-08 31.4 0.0 2.9e-07 29.5 0.0 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMC76800.1 - 0.00012 20.5 0.0 0.00018 19.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EMC76800.1 - 0.00086 18.5 0.0 0.0014 17.8 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EMC76800.1 - 0.11 11.0 0.0 1.6 7.1 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain 7tm_1 PF00001.16 EMC76801.1 - 2.1e-56 190.9 18.8 2.5e-56 190.7 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC76801.1 - 9e-09 34.8 12.9 1.1e-06 28.0 8.9 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF420 PF04238.7 EMC76801.1 - 0.58 10.1 11.5 0.11 12.4 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF420) DUF3585 PF12130.3 EMC76802.1 - 6.5e-50 168.6 13.4 1e-49 168.0 9.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) LIM PF00412.17 EMC76802.1 - 4.5e-09 36.2 4.2 8.4e-09 35.3 2.9 1.4 1 0 0 1 1 1 1 LIM domain CH PF00307.26 EMC76802.1 - 2.7e-06 27.3 0.0 4.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain UPF0193 PF05250.6 EMC76803.1 - 6.6e-46 156.5 2.8 8.1e-46 156.2 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) LEA_1 PF03760.10 EMC76803.1 - 0.17 12.0 0.2 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Sox_N PF12444.3 EMC76804.1 - 1e-25 90.6 0.3 1e-25 90.6 0.2 2.6 3 1 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.14 EMC76804.1 - 2e-24 85.6 1.4 3.4e-24 84.9 1.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC76804.1 - 4.8e-10 39.6 0.9 4.8e-10 39.6 0.6 1.7 2 0 0 2 2 2 1 HMG-box domain MAT_Alpha1 PF04769.7 EMC76804.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Arfaptin PF06456.8 EMC76805.1 - 1.9e-84 282.6 2.1 3e-84 281.9 1.4 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.19 EMC76805.1 - 1.1e-10 41.5 0.1 2.1e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC76805.1 - 4.6e-06 26.4 0.1 3.1e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 PDZ domain BAR PF03114.13 EMC76805.1 - 1.1e-05 25.1 2.2 3e-05 23.6 1.3 1.9 1 1 1 2 2 2 1 BAR domain GRASP55_65 PF04495.9 EMC76805.1 - 0.044 13.7 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain RE_R_Pab1 PF09522.5 EMC76805.1 - 0.24 11.3 1.9 9 6.2 0.0 3.3 3 1 1 4 4 4 0 R.Pab1 restriction endonuclease MFS_1 PF07690.11 EMC76806.1 - 3.9e-36 124.4 17.9 5.4e-28 97.7 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC76806.1 - 0.011 15.4 6.9 1.3 8.9 0.1 3.7 3 0 0 3 3 3 0 MFS_1 like family Ank_2 PF12796.2 EMC76807.1 - 2.6e-56 187.9 16.2 1e-15 57.7 0.1 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMC76807.1 - 4.7e-38 127.1 8.8 1.5e-07 30.8 0.1 7.6 6 1 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EMC76807.1 - 1.4e-29 99.1 6.7 1.7e-05 24.5 0.1 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EMC76807.1 - 1.1e-26 92.2 8.6 1.4e-07 31.5 0.0 7.6 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC76807.1 - 1.9e-26 91.9 5.2 2.4e-09 37.4 0.0 6.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Patatin PF01734.17 EMC76807.1 - 8.7e-20 71.5 1.1 3.5e-19 69.5 0.8 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3109 PF11307.3 EMC76807.1 - 0.14 11.6 0.5 0.29 10.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) bZIP_Maf PF03131.12 EMC76808.1 - 8.1e-33 112.5 8.4 1e-32 112.2 5.8 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EMC76808.1 - 0.0092 15.7 7.8 0.0092 15.7 5.4 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC76808.1 - 0.014 15.3 13.1 0.056 13.4 8.6 2.2 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EMC76808.1 - 0.025 14.0 1.1 0.025 14.0 0.8 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 EMC76808.1 - 0.041 13.6 0.4 0.041 13.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) IncA PF04156.9 EMC76808.1 - 0.1 12.1 2.0 0.24 10.9 1.3 1.7 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 EMC76808.1 - 0.1 12.9 2.6 0.22 11.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 EMC76808.1 - 0.98 8.5 6.2 2.1 7.4 4.3 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 EMC76808.1 - 1.1 9.0 8.9 0.45 10.2 0.4 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF904 PF06005.7 EMC76808.1 - 4.1 7.7 8.4 23 5.3 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 EMC76808.1 - 6.6 7.2 6.3 2.3e+02 2.2 4.4 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Solute_trans_a PF03619.11 EMC76809.1 - 1.2e-98 329.8 19.2 1.4e-98 329.5 13.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1282 PF06930.7 EMC76809.1 - 0.24 11.0 11.0 0.074 12.7 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Pkinase PF00069.20 EMC76810.1 - 1.2e-30 106.6 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC76810.1 - 2.2e-12 46.6 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC76810.1 - 0.0001 22.1 0.5 0.00064 19.5 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMC76810.1 - 0.028 13.2 0.2 0.04 12.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IRK PF01007.15 EMC76811.1 - 2.8e-170 565.5 0.0 3.3e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC76811.1 - 0.098 12.3 13.3 0.64 9.7 9.2 2.2 1 1 0 1 1 1 0 Ion channel CCDC155 PF14662.1 EMC76812.1 - 0.0001 21.9 13.6 0.00022 20.9 9.4 1.5 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 BRE1 PF08647.6 EMC76812.1 - 0.00018 21.3 3.8 0.00018 21.3 2.7 2.5 2 1 1 3 3 2 1 BRE1 E3 ubiquitin ligase Laminin_II PF06009.7 EMC76812.1 - 0.00021 21.0 6.7 0.013 15.2 3.3 2.9 1 1 2 3 3 3 1 Laminin Domain II DASH_Dad4 PF08650.5 EMC76812.1 - 0.00054 19.8 2.1 0.0021 17.9 0.1 2.5 1 1 2 3 3 3 1 DASH complex subunit Dad4 Tropomyosin PF00261.15 EMC76812.1 - 0.00098 18.2 10.8 0.002 17.2 7.4 1.5 1 1 0 1 1 1 1 Tropomyosin DUF1640 PF07798.6 EMC76812.1 - 0.004 17.2 5.5 0.0057 16.7 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3926 PF13080.1 EMC76812.1 - 0.0042 16.5 1.3 0.011 15.2 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3926) RILP PF11461.3 EMC76812.1 - 0.0045 17.1 0.2 0.014 15.5 0.1 1.8 1 0 0 1 1 1 1 Rab interacting lysosomal protein Lebercilin PF15619.1 EMC76812.1 - 0.0048 16.3 10.3 0.36 10.2 0.2 2.3 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.14 EMC76812.1 - 0.008 15.7 8.0 0.0086 15.6 5.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family bZIP_Maf PF03131.12 EMC76812.1 - 0.017 15.4 10.1 0.13 12.5 2.8 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor Spc7 PF08317.6 EMC76812.1 - 0.02 13.5 9.0 0.024 13.2 6.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Borrelia_lipo_1 PF05714.6 EMC76812.1 - 0.028 13.5 2.2 0.043 12.9 1.5 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein RRF_GI PF12614.3 EMC76812.1 - 0.04 13.7 2.9 0.085 12.6 2.0 1.6 1 0 0 1 1 1 0 Ribosome recycling factor DUF4200 PF13863.1 EMC76812.1 - 0.049 13.5 11.7 0.083 12.8 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EMC76812.1 - 0.18 9.6 4.7 0.19 9.5 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EMC76812.1 - 0.19 10.7 9.8 0.15 11.1 6.2 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EMC76812.1 - 0.29 10.7 10.1 0.43 10.1 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phlebovirus_NSM PF07246.6 EMC76812.1 - 0.36 9.9 5.0 0.48 9.5 3.5 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Atg14 PF10186.4 EMC76812.1 - 0.4 9.5 5.9 0.5 9.2 4.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3972 PF13118.1 EMC76812.1 - 0.42 10.7 6.3 0.54 10.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Fib_alpha PF08702.5 EMC76812.1 - 0.6 10.2 8.3 1.1 9.4 5.1 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rootletin PF15035.1 EMC76812.1 - 0.62 10.0 14.6 4 7.3 10.2 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF342 PF03961.8 EMC76812.1 - 0.69 8.2 5.1 0.84 7.9 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 EMC76812.1 - 0.83 10.0 12.9 1.2 9.4 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 EMC76812.1 - 0.97 8.5 12.4 0.75 8.9 1.3 2.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding HR1 PF02185.11 EMC76812.1 - 1 9.1 13.4 30 4.4 0.0 3.7 2 1 1 3 3 3 0 Hr1 repeat TSC22 PF01166.13 EMC76812.1 - 1.1 9.2 10.9 0.56 10.2 1.3 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 EMC76812.1 - 1.1 8.9 12.0 7.3 6.3 8.3 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.1 EMC76812.1 - 1.6 8.8 8.4 2 8.5 1.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DivIC PF04977.10 EMC76812.1 - 2 7.9 7.7 2.9 7.4 0.6 3.2 1 1 3 4 4 4 0 Septum formation initiator DUF1664 PF07889.7 EMC76812.1 - 3.2 7.5 6.6 17 5.1 3.1 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) HALZ PF02183.13 EMC76812.1 - 6.3 6.5 11.5 4.5 7.0 0.2 3.8 4 1 1 5 5 4 0 Homeobox associated leucine zipper ER_lumen_recept PF00810.13 EMC76813.1 - 6.4e-44 150.0 13.2 2.4e-43 148.1 9.1 1.9 1 1 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EMC76813.1 - 0.011 15.2 1.4 0.011 15.2 1.0 3.2 3 0 0 3 3 3 0 PQ loop repeat DEAD PF00270.24 EMC76814.1 - 2.4e-45 154.0 0.0 4.8e-44 149.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC76814.1 - 6.4e-26 90.0 0.0 1.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC76814.1 - 0.007 16.2 0.0 0.029 14.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ferritin PF00210.19 EMC76814.1 - 0.0088 15.8 0.8 0.031 14.0 0.5 1.9 1 1 0 1 1 1 1 Ferritin-like domain Helicase_C_2 PF13307.1 EMC76814.1 - 0.054 13.4 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Rad51 PF08423.6 EMC76815.1 - 2.8e-122 406.5 0.1 3.6e-122 406.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMC76815.1 - 3.9e-10 39.4 0.0 5.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EMC76815.1 - 4.6e-10 39.0 0.0 6.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EMC76815.1 - 2.9e-07 29.8 0.1 5.6e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EMC76815.1 - 2.6e-06 27.5 0.1 5.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF128 PF01995.11 EMC76815.1 - 0.0039 16.1 0.0 0.007 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF128 HHH PF00633.18 EMC76815.1 - 0.07 12.8 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Chibby PF14645.1 EMC76816.1 - 1.5e-50 169.9 0.5 1.7e-50 169.7 0.4 1.0 1 0 0 1 1 1 1 Chibby family Taxilin PF09728.4 EMC76816.1 - 0.0016 17.6 2.0 0.0019 17.3 1.4 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein UPF0242 PF06785.6 EMC76816.1 - 0.0019 16.9 1.9 0.002 16.8 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) DUF972 PF06156.8 EMC76816.1 - 0.029 14.7 3.8 0.044 14.1 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2051 PF09738.4 EMC76816.1 - 0.04 13.1 5.4 0.051 12.8 3.7 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Shugoshin_N PF07558.6 EMC76816.1 - 0.92 9.2 10.5 0.33 10.6 3.0 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 EMC76816.1 - 1.1 9.1 10.8 0.15 11.8 3.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 EMC76816.1 - 2.9 7.7 10.0 4.2 7.2 6.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EMC76816.1 - 4 6.9 6.5 2 7.9 2.2 1.9 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.13 EMC76816.1 - 4.9 7.1 9.1 0.57 10.1 1.6 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family Tom22 PF04281.8 EMC76817.1 - 0.025 14.1 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Josephin PF02099.12 EMC76818.1 - 5.3e-20 71.6 0.0 6.4e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Josephin KH_1 PF00013.24 EMC76819.1 - 2e-52 174.6 13.9 1.6e-17 62.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMC76819.1 - 6.3e-40 134.1 20.0 1.3e-13 50.2 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMC76819.1 - 4.9e-17 61.2 6.2 2e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMC76819.1 - 5e-08 32.4 2.0 0.014 15.0 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMC76819.1 - 2.1e-05 24.2 6.0 0.38 10.5 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain DUF370 PF04025.7 EMC76819.1 - 0.025 14.6 0.9 4.3 7.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF370) Myosin_tail_1 PF01576.14 EMC76820.1 - 0 1104.2 284.6 0 1085.6 150.7 3.1 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 EMC76820.1 - 1.8e-215 717.0 0.7 1.8e-215 717.0 0.5 3.9 3 1 2 5 5 5 1 Myosin head (motor domain) Filament PF00038.16 EMC76820.1 - 2.1e-06 27.4 238.3 0.00013 21.5 37.2 8.2 1 1 4 5 5 5 3 Intermediate filament protein Reo_sigmaC PF04582.7 EMC76820.1 - 8.6e-06 25.1 76.6 0.011 14.9 2.9 9.1 2 2 7 10 10 10 8 Reovirus sigma C capsid protein IQ PF00612.22 EMC76820.1 - 0.0016 17.8 1.7 0.0092 15.5 0.3 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif Macro PF01661.16 EMC76820.1 - 0.91 9.4 8.4 1.8 8.4 0.0 4.4 4 0 0 4 4 4 0 Macro domain TRAP_beta PF05753.9 EMC76821.1 - 2e-33 115.0 0.0 2.3e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Cpn60_TCP1 PF00118.19 EMC76822.1 - 1.4e-135 452.6 4.1 5.9e-135 450.6 2.9 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RusA PF05866.6 EMC76822.1 - 0.042 14.2 0.0 6.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA NCU-G1 PF15065.1 EMC76823.1 - 2.6e-103 345.4 0.0 3e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 MAPEG PF01124.13 EMC76824.1 - 1.9e-05 24.2 8.3 3.5e-05 23.4 5.8 1.4 1 0 0 1 1 1 1 MAPEG family DUF4149 PF13664.1 EMC76824.1 - 1.9 8.5 10.4 13 5.8 7.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Nnf1 PF03980.9 EMC76825.1 - 4.4e-26 90.9 0.2 6.4e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Nnf1 Erp_C PF06780.6 EMC76825.1 - 0.1 12.4 0.7 0.22 11.3 0.1 1.7 1 1 1 2 2 2 0 Erp protein C-terminus Mito_carr PF00153.22 EMC76826.1 - 8.4e-51 169.6 7.6 2.8e-16 58.9 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein NPR2 PF06218.6 EMC76826.1 - 0.016 13.9 1.1 0.051 12.2 0.1 1.9 1 1 1 2 2 2 0 Nitrogen permease regulator 2 Sema PF01403.14 EMC76827.1 - 8.3e-123 410.1 0.0 1e-122 409.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 EMC76827.1 - 3.8e-06 26.9 5.3 9e-06 25.7 3.7 1.7 1 0 0 1 1 1 1 Plexin repeat Plasmodium_HRP PF05403.6 EMC76828.1 - 8.8 5.8 7.8 3.2e+02 0.7 5.4 3.1 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) CDC27 PF09507.5 EMC76830.1 - 3.6e-108 362.5 25.6 4.1e-108 362.3 17.7 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 VWC PF00093.13 EMC76831.1 - 1.2e-26 92.5 49.7 7.5e-11 41.9 8.2 3.3 3 0 0 3 3 3 3 von Willebrand factor type C domain DUF3601 PF12208.3 EMC76831.1 - 0.029 14.2 0.2 18 5.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) Calpain_III PF01067.17 EMC76832.1 - 2e-10 40.5 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Pol_alpha_B_N PF08418.5 EMC76832.1 - 2.7e-06 27.1 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Peptidase_C2 PF00648.16 EMC76832.1 - 0.063 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Calpain family cysteine protease OTU PF02338.14 EMC76833.1 - 0.047 14.2 0.2 0.71 10.4 0.0 2.5 2 2 0 2 2 2 0 OTU-like cysteine protease Peptidase_C65 PF10275.4 EMC76833.1 - 0.075 12.3 2.1 0.75 9.1 0.0 2.6 2 1 0 2 2 2 0 Peptidase C65 Otubain DUF2346 PF09803.4 EMC76833.1 - 6.8 6.6 7.3 6.6 6.6 0.2 3.5 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2346) Arm PF00514.18 EMC76836.1 - 1.8e-46 154.4 9.6 3.9e-09 36.0 0.0 9.0 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC76836.1 - 8.8e-11 41.9 0.8 8.1e-05 22.8 0.0 3.4 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EMC76836.1 - 3.5e-05 23.5 3.2 0.89 9.8 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 EMC76836.1 - 0.0063 14.8 0.0 0.37 9.0 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EMC76836.1 - 0.019 15.4 4.5 36 5.0 0.1 5.1 4 1 1 5 5 5 0 HEAT-like repeat DAP PF15228.1 EMC76837.1 - 3.5e-25 88.5 8.2 3.9e-25 88.4 5.7 1.0 1 0 0 1 1 1 1 Death-associated protein Ank_5 PF13857.1 EMC76838.1 - 1.1e-15 57.2 1.8 3.8e-06 26.9 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC76838.1 - 2.7e-15 56.4 0.1 8.8e-15 54.8 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC76838.1 - 3.1e-14 53.0 0.3 1.8e-06 28.2 0.3 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC76838.1 - 1.7e-12 46.4 0.6 3.2e-06 26.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EMC76838.1 - 1.8e-11 43.1 0.3 0.0024 17.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Troponin-I_N PF11636.3 EMC76838.1 - 3.6 7.3 6.7 0.42 10.3 1.4 1.9 2 0 0 2 2 2 0 Troponin I residues 1-32 BSP_II PF05432.6 EMC76839.1 - 0.036 13.3 5.0 0.049 12.9 3.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleo_P87 PF07267.6 EMC76840.1 - 0.068 11.8 12.0 0.081 11.5 8.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RINGv PF12906.2 EMC76842.1 - 1.3e-14 53.9 9.0 2.9e-14 52.8 6.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EMC76842.1 - 0.16 11.8 8.7 0.48 10.2 6.1 1.9 1 0 0 1 1 1 0 Ring finger domain DLH PF01738.13 EMC76843.1 - 1.2e-33 116.2 0.0 1.3e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC76843.1 - 3.5e-12 46.2 0.0 4.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC76843.1 - 4.3e-09 36.1 0.0 5.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMC76843.1 - 4.6e-09 36.4 0.0 4.8e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC76843.1 - 7.3e-07 28.6 0.2 0.0028 16.8 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMC76843.1 - 8.8e-06 25.4 0.5 0.0032 17.0 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMC76843.1 - 2.8e-05 23.8 0.0 0.12 11.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EMC76843.1 - 3.3e-05 22.9 0.0 4.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMC76843.1 - 0.00016 20.5 0.0 0.00025 19.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase FSH1 PF03959.8 EMC76843.1 - 0.0036 16.7 0.1 0.015 14.7 0.1 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 EMC76843.1 - 0.04 13.3 0.1 0.056 12.8 0.1 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) tRNA-synt_2b PF00587.20 EMC76843.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DLH PF01738.13 EMC76844.1 - 2.1e-30 105.6 0.0 2.3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC76844.1 - 2.1e-09 37.2 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC76844.1 - 8.8e-07 28.5 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMC76844.1 - 1.5e-06 27.5 0.1 5.2e-06 25.8 0.0 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMC76844.1 - 1.7e-05 24.5 0.2 0.0013 18.3 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC76844.1 - 9e-05 22.4 0.0 0.42 10.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 EMC76844.1 - 0.00049 19.2 0.0 0.0013 17.8 0.0 1.5 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 EMC76844.1 - 0.0054 16.3 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EMC76844.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF676 PF05057.9 EMC76844.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.13 EMC76846.1 - 5.5e-41 140.2 0.0 6.3e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC76846.1 - 1.3e-11 44.4 0.0 1.7e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC76846.1 - 7.4e-09 35.8 0.0 6.2e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC76846.1 - 4.2e-08 32.9 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMC76846.1 - 3.7e-07 29.5 0.2 1e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMC76846.1 - 1.2e-05 24.9 0.1 0.0013 18.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EMC76846.1 - 0.0077 15.6 0.1 0.029 13.8 0.1 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EMC76846.1 - 0.024 14.1 0.1 0.13 11.7 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Pkinase PF00069.20 EMC76847.1 - 4.6e-43 147.2 0.0 5.5e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC76847.1 - 2.7e-22 79.0 0.0 3.2e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC76847.1 - 3.8e-06 26.0 0.0 2.8e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like GRDA PF04723.9 EMC76847.1 - 0.083 12.6 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A Cpn60_TCP1 PF00118.19 EMC76848.1 - 9.1e-147 489.5 1.4 1.1e-146 489.2 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltransf_18 PF12847.2 EMC76849.1 - 1.4e-06 28.8 0.0 1.9e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC76849.1 - 1.7e-06 28.0 0.0 3.9e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC76849.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC76849.1 - 0.00042 19.7 0.0 0.00052 19.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EMC76849.1 - 0.0007 19.2 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EMC76849.1 - 0.007 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PrmA PF06325.8 EMC76849.1 - 0.022 13.9 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EMC76849.1 - 0.041 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase N6_N4_Mtase PF01555.13 EMC76849.1 - 0.042 13.3 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Met_10 PF02475.11 EMC76849.1 - 0.045 13.3 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein N2227 PF07942.7 EMC76849.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein CMAS PF02353.15 EMC76849.1 - 0.12 11.3 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 7tm_4 PF13853.1 EMC76850.1 - 9.3e-51 171.4 9.9 1.1e-50 171.2 6.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC76850.1 - 5.4e-05 22.4 6.3 6.9e-05 22.1 4.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 EMC76850.1 - 0.025 14.5 1.6 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Claudin_2 PF13903.1 EMC76850.1 - 0.35 10.5 3.3 0.45 10.1 2.3 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.18 EMC76850.1 - 2 8.2 8.6 4.2 7.1 0.4 2.3 1 1 0 2 2 2 0 Membrane-associating domain bZIP_2 PF07716.10 EMC76851.1 - 6.2e-07 29.1 18.8 1.2e-06 28.2 13.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC76851.1 - 1.6e-06 27.9 17.9 2.9e-06 27.1 12.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EMC76851.1 - 0.00088 19.5 13.3 0.0014 18.8 9.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Phage_lysis PF03245.8 EMC76851.1 - 0.0033 17.4 1.0 0.0048 16.8 0.7 1.2 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein DUF3535 PF12054.3 EMC76851.1 - 0.0055 15.3 0.2 0.0075 14.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) Uso1_p115_C PF04871.8 EMC76851.1 - 0.081 12.8 6.7 0.13 12.2 4.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region IncA PF04156.9 EMC76851.1 - 0.11 12.1 8.4 0.19 11.3 5.8 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EMC76851.1 - 0.57 9.7 7.7 0.57 9.7 4.7 1.5 1 1 0 1 1 1 0 Septum formation initiator ERM PF00769.14 EMC76851.1 - 0.6 9.6 14.3 0.85 9.1 9.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.4 EMC76851.1 - 1 8.2 5.8 1.3 7.8 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HemX PF04375.9 EMC76851.1 - 1.1 7.7 4.7 1.6 7.2 3.2 1.1 1 0 0 1 1 1 0 HemX DUF342 PF03961.8 EMC76851.1 - 1.3 7.4 3.3 1.6 7.0 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EMC76851.1 - 3.6 6.5 9.7 5 6.0 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMC76851.1 - 4 5.1 4.3 5.1 4.8 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HMG14_17 PF01101.13 EMC76852.1 - 1.2e-13 51.5 38.5 4.6e-13 49.6 26.7 1.7 1 1 0 1 1 1 1 HMG14 and HMG17 Pap_E4 PF02711.9 EMC76852.1 - 6.3 7.7 10.7 14 6.5 7.4 1.7 1 1 0 1 1 1 0 E4 protein SH3BGR PF04908.10 EMC76853.1 - 3.1e-36 123.2 0.1 3.7e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EMC76853.1 - 0.00055 19.8 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF4569 PF15133.1 EMC76854.1 - 3.3e-98 328.8 0.2 3.8e-98 328.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) Na_H_Exchanger PF00999.16 EMC76855.1 - 3e-80 269.5 35.6 3.5e-80 269.3 24.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Claudin_2 PF13903.1 EMC76856.1 - 2.2e-24 86.0 2.9 3.3e-24 85.4 2.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC76856.1 - 0.0047 16.5 9.6 0.07 12.7 4.0 2.7 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family TMEM61 PF15105.1 EMC76856.1 - 0.075 12.5 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 TMEM61 protein family Pkinase PF00069.20 EMC76857.1 - 2.3e-144 479.2 0.0 1.3e-71 240.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC76857.1 - 6.2e-76 254.8 0.0 8.4e-40 136.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC76857.1 - 3.5e-14 52.4 0.0 1.4e-07 30.8 0.0 3.7 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 EMC76857.1 - 4e-10 39.1 0.0 1.6e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC76857.1 - 2e-06 27.7 0.1 0.15 11.7 0.0 3.4 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pkinase_C PF00433.19 EMC76857.1 - 3.5e-06 27.4 1.0 7.9e-06 26.3 0.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.4 EMC76857.1 - 4.2e-06 26.2 0.0 0.0087 15.4 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMC76857.1 - 0.006 15.9 0.0 0.35 10.1 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EMC76857.1 - 0.048 13.2 0.1 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EMC76857.1 - 0.13 11.0 0.1 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Homeobox PF00046.24 EMC76859.1 - 3.7e-11 42.4 2.0 6.3e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Homeobox domain DUF1170 PF06663.8 EMC76860.1 - 1.1e-60 204.7 1.8 2.1e-60 203.8 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 EMC76860.1 - 6.3e-41 138.3 1.5 9.9e-41 137.7 0.1 2.1 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.25 EMC76860.1 - 3.5e-19 68.7 0.5 9.1e-19 67.3 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EMC76860.1 - 5.4e-14 52.2 2.0 1.6e-13 50.7 1.4 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 EMC76860.1 - 2.3e-13 49.7 0.8 6e-13 48.4 0.3 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 EMC76860.1 - 4.5e-10 39.5 0.0 1.6e-08 34.5 0.0 2.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SAM_PNT PF02198.11 EMC76860.1 - 0.0018 18.0 0.1 0.0042 16.8 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ_2 PF13180.1 EMC76860.1 - 0.0054 16.6 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.1 EMC76860.1 - 0.02 15.1 7.8 0.095 12.9 5.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.1 EMC76860.1 - 0.059 13.5 1.9 1.9 8.6 0.8 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain SNARE PF05739.14 EMC76861.1 - 3.5e-14 52.2 1.3 3.5e-14 52.2 0.9 2.4 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EMC76861.1 - 5.9e-08 32.8 1.3 8.9e-07 29.0 0.0 2.4 3 0 0 3 3 3 1 Syntaxin DUF2259 PF10016.4 EMC76861.1 - 0.017 14.8 0.1 0.072 12.8 0.1 1.9 1 1 0 1 1 1 0 Predicted secreted protein (DUF2259) V_ATPase_I PF01496.14 EMC76861.1 - 0.039 11.8 1.7 0.057 11.2 1.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RasGAP_C PF03836.10 EMC76861.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 RasGAP C-terminus Muted PF14942.1 EMC76861.1 - 0.41 10.5 5.4 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Uds1 PF15456.1 EMC76861.1 - 8.3 6.4 10.0 3 7.8 3.2 2.4 2 1 0 2 2 2 0 Up-regulated During Septation SNARE PF05739.14 EMC76862.1 - 7.4e-25 86.4 1.1 7.4e-25 86.4 0.8 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EMC76862.1 - 2.1e-23 82.4 3.3 2.1e-23 82.4 2.3 3.5 2 2 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EMC76862.1 - 0.0025 17.8 2.3 0.011 15.7 0.0 2.7 2 2 0 2 2 2 1 Syntaxin-like protein DUF724 PF05266.9 EMC76862.1 - 0.055 13.0 3.6 0.81 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) MCPsignal PF00015.16 EMC76862.1 - 0.056 12.9 3.4 0.8 9.2 0.8 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Lzipper-MIP1 PF14389.1 EMC76862.1 - 0.13 12.3 1.9 0.41 10.7 0.0 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MCM_N PF14551.1 EMC76862.1 - 0.16 12.4 1.3 0.47 10.9 0.9 1.7 1 1 0 1 1 1 0 MCM N-terminal domain CENP-Q PF13094.1 EMC76862.1 - 0.16 11.9 3.1 5.4 7.0 0.0 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YtxH PF12732.2 EMC76862.1 - 0.2 12.0 3.9 0.17 12.2 1.0 2.5 2 1 0 2 2 1 0 YtxH-like protein DUF1640 PF07798.6 EMC76862.1 - 0.29 11.1 8.9 0.2 11.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.17 EMC76862.1 - 0.6 10.1 4.9 0.76 9.8 0.7 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 EMC76862.1 - 0.69 10.3 5.5 5.4 7.4 0.6 3.0 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Sec2p PF06428.6 EMC76862.1 - 0.98 9.3 5.6 0.56 10.0 0.4 2.6 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p TBPIP PF07106.8 EMC76862.1 - 0.99 8.9 8.6 1.3 8.5 0.4 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG5 PF10392.4 EMC76862.1 - 1.3 9.0 5.6 3.2 7.7 0.5 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF2408 PF10303.4 EMC76862.1 - 1.6 8.8 5.1 10 6.2 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) SF-assemblin PF06705.6 EMC76862.1 - 1.8 7.6 11.4 3.8 6.5 4.5 2.2 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF948 PF06103.6 EMC76862.1 - 2.9 7.8 6.8 4.6 7.1 1.0 3.2 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.1 EMC76862.1 - 3.2 8.2 5.8 1.7 9.1 0.5 2.8 3 2 1 4 4 3 0 Domain of unknown function (DUF4404) Phage_GP20 PF06810.6 EMC76862.1 - 8.6 5.7 9.1 0.66 9.4 0.2 2.8 3 1 1 4 4 4 0 Phage minor structural protein GP20 zf-C2H2 PF00096.21 EMC76863.1 - 7.1e-13 48.0 9.3 1.5e-06 28.1 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC76863.1 - 3.6e-11 42.7 9.2 1.7e-06 27.9 0.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC76863.1 - 5.3e-08 32.6 6.7 2.4e-05 24.3 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC76863.1 - 5.4e-08 32.4 7.1 3.5e-05 23.5 0.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EMC76863.1 - 6.7e-05 22.9 7.6 0.0012 18.9 0.4 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC76863.1 - 0.00013 21.9 2.1 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EMC76863.1 - 0.0011 18.8 3.3 0.11 12.4 0.1 2.3 2 1 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.13 EMC76863.1 - 0.014 15.0 0.7 4.9 6.9 0.1 2.4 2 0 0 2 2 2 0 XPA protein N-terminal RRN7 PF11781.3 EMC76863.1 - 0.02 14.4 0.8 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 ADK_lid PF05191.9 EMC76863.1 - 0.046 13.3 5.2 0.064 12.9 1.5 2.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid DZR PF12773.2 EMC76863.1 - 0.072 12.9 3.6 0.2 11.4 2.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-LYAR PF08790.6 EMC76863.1 - 0.074 12.7 4.3 0.94 9.2 0.3 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EMC76863.1 - 0.079 12.5 1.1 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain Prok-RING_1 PF14446.1 EMC76863.1 - 0.085 12.6 2.7 4 7.2 0.1 2.2 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 LIM PF00412.17 EMC76863.1 - 0.088 12.8 3.3 1.5 8.9 2.3 2.2 1 1 0 1 1 1 0 LIM domain DUF2688 PF10892.3 EMC76863.1 - 0.093 12.4 1.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) UPF0547 PF10571.4 EMC76863.1 - 0.093 12.4 1.7 2.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-AN1 PF01428.11 EMC76863.1 - 0.094 12.5 3.2 0.43 10.4 0.2 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger YhfH PF14149.1 EMC76863.1 - 0.097 12.4 0.4 8 6.3 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein DUF2256 PF10013.4 EMC76863.1 - 0.12 12.1 1.3 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Ta0938 PF11494.3 EMC76863.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Ta0938 C1_1 PF00130.17 EMC76863.1 - 0.12 12.0 5.8 1.6 8.5 0.4 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.8 EMC76863.1 - 0.14 11.6 4.6 6.8 6.2 3.4 2.4 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Cript PF10235.4 EMC76863.1 - 0.2 12.0 2.1 2.3 8.6 1.5 2.1 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT HNH PF01844.18 EMC76863.1 - 0.21 11.4 4.4 22 5.0 0.4 3.1 2 1 1 3 3 3 0 HNH endonuclease zf-C2HC_2 PF13913.1 EMC76863.1 - 0.3 10.7 3.3 5 6.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Evr1_Alr PF04777.8 EMC76863.1 - 0.41 10.5 2.6 1.7 8.6 0.2 2.0 1 1 1 2 2 2 0 Erv1 / Alr family DUF1610 PF07754.6 EMC76863.1 - 0.43 10.7 7.0 0.96 9.6 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) C1_3 PF07649.7 EMC76863.1 - 0.49 10.4 3.4 10 6.2 0.1 2.2 2 0 0 2 2 2 0 C1-like domain Zn_ribbon_recom PF13408.1 EMC76863.1 - 0.7 10.2 3.3 16 5.8 2.3 2.2 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain A2L_zn_ribbon PF08792.5 EMC76863.1 - 0.91 9.0 3.2 5.8 6.5 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain FYVE PF01363.16 EMC76863.1 - 1.2 9.0 5.8 7 6.6 4.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger Ribosomal_L31 PF01197.13 EMC76865.1 - 0.043 13.8 8.3 19 5.3 0.0 5.1 1 1 3 4 4 4 0 Ribosomal protein L31 Neisseria_TspB PF05616.8 EMC76865.1 - 0.059 11.7 4.2 0.056 11.8 0.7 2.1 1 1 1 2 2 2 0 Neisseria meningitidis TspB protein DUF4397 PF14344.1 EMC76865.1 - 0.43 10.9 6.7 2.3 8.5 0.4 3.2 1 1 4 5 5 5 0 Domain of unknown function (DUF4397) Amidohydro_1 PF01979.15 EMC76866.1 - 5.6e-06 26.2 0.0 8.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC76866.1 - 0.0011 19.0 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC76866.1 - 0.0048 16.1 0.0 0.0062 15.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family EB1 PF03271.12 EMC76867.1 - 1.7e-16 60.0 0.1 3.8e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EMC76867.1 - 0.00054 19.9 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CPSase_sm_chain PF00988.17 EMC76868.1 - 3.4e-18 65.4 0.1 3.6e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain UPRTase PF14681.1 EMC76870.1 - 7.2e-64 214.7 0.0 1.4e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EMC76870.1 - 1.9e-28 99.3 0.4 2.8e-28 98.8 0.3 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cation_efflux PF01545.16 EMC76871.1 - 6.5e-43 146.8 0.6 7.2e-43 146.6 0.4 1.0 1 0 0 1 1 1 1 Cation efflux family DUF4282 PF14110.1 EMC76871.1 - 3.9 7.7 6.7 0.37 11.0 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) WD40 PF00400.27 EMC76872.1 - 2.5e-12 46.1 4.1 2e-07 30.6 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ST7 PF04184.7 EMC76873.1 - 0 1030.1 1.6 0 1030.0 1.1 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.1 EMC76873.1 - 0.00013 22.1 0.5 0.00057 20.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.15 EMC76873.1 - 0.041 13.4 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_2 PF07719.12 EMC76873.1 - 0.12 12.2 5.7 2.6 8.1 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC76873.1 - 0.13 11.9 2.8 20 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC76873.1 - 3.2 8.1 7.3 1.3 9.3 0.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat F-actin_cap_A PF01267.12 EMC76875.1 - 8.9e-99 329.9 2.6 1e-98 329.7 1.8 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Sema PF01403.14 EMC76876.1 - 3.3e-106 355.4 5.0 5e-106 354.8 3.5 1.2 1 0 0 1 1 1 1 Sema domain Pkinase_Tyr PF07714.12 EMC76876.1 - 8.3e-94 313.4 0.0 1.2e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC76876.1 - 3.6e-43 147.6 0.0 6.5e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 EMC76876.1 - 1.6e-32 111.3 10.7 1.1e-13 50.9 0.1 5.0 4 0 0 4 4 4 4 IPT/TIG domain PSI PF01437.20 EMC76876.1 - 2.8e-07 30.5 15.1 1.1e-06 28.6 10.5 2.2 1 0 0 1 1 1 1 Plexin repeat Kinase-like PF14531.1 EMC76876.1 - 2.3e-05 23.4 0.0 5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Adeno_E3_CR2 PF02439.10 EMC76876.1 - 0.0055 16.2 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.15 EMC76876.1 - 0.027 14.1 0.2 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain YajC PF02699.10 EMC76876.1 - 0.13 11.9 0.1 0.33 10.6 0.1 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit Caveolin PF01146.12 EMC76877.1 - 1.1e-67 226.1 1.6 1.2e-67 226.0 1.1 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.12 EMC76878.1 - 2.9e-53 179.4 6.8 3.1e-53 179.3 4.7 1.0 1 0 0 1 1 1 1 Caveolin DUF2512 PF10710.4 EMC76878.1 - 2 7.8 6.4 1.6 8.2 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) DUF1700 PF08006.6 EMC76878.1 - 8.8 5.5 7.3 11 5.3 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PET PF06297.9 EMC76879.1 - 9.4e-43 144.1 1.2 1.6e-42 143.4 0.9 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 EMC76879.1 - 3.4e-24 84.6 26.1 1.1e-13 50.9 7.3 4.2 3 2 1 4 4 4 2 LIM domain Mod_r PF07200.8 EMC76879.1 - 0.12 12.2 0.5 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3371 PF11851.3 EMC76881.1 - 1.3e-38 132.6 3.8 1.3e-38 132.6 2.6 3.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3371) HLH PF00010.21 EMC76881.1 - 1.3e-15 56.7 0.4 3.3e-15 55.5 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MDFI PF15316.1 EMC76882.1 - 1.3e-74 249.9 40.9 1.4e-74 249.8 28.3 1.0 1 0 0 1 1 1 1 MyoD family inhibitor Fork_head PF00250.13 EMC76883.1 - 5.8e-36 122.4 0.0 6.8e-36 122.1 0.0 1.0 1 0 0 1 1 1 1 Fork head domain Linker_histone PF00538.14 EMC76883.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family BssC_TutF PF08201.6 EMC76883.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 BssC/TutF protein CBM_21 PF03370.8 EMC76884.1 - 6.4e-29 100.2 0.1 1.5e-28 99.0 0.1 1.7 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit 7tm_1 PF00001.16 EMC76885.1 - 1.6e-37 129.0 10.9 2.3e-37 128.5 7.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Arteri_Gl PF00951.13 EMC76885.1 - 1.3 8.6 10.2 4.1 6.9 4.2 2.5 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF3321 PF11968.3 EMC76886.1 - 4.3e-08 33.0 0.3 2.5e-05 24.0 0.2 2.1 1 1 1 2 2 2 2 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EMC76886.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C14 PF00656.17 EMC76887.1 - 0.03 14.0 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Caspase domain DUF4577 PF15145.1 EMC76888.1 - 9.9e-42 141.8 0.5 1.1e-41 141.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) Tetraspannin PF00335.15 EMC76888.1 - 0.0017 17.6 0.1 0.0021 17.3 0.1 1.1 1 0 0 1 1 1 1 Tetraspanin family CCSMST1 PF15013.1 EMC76888.1 - 0.0029 17.4 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 CCSMST1 family DUF4014 PF13198.1 EMC76888.1 - 0.023 15.0 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) DUF2254 PF10011.4 EMC76888.1 - 0.095 11.1 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) MscL PF01741.13 EMC76888.1 - 0.1 12.7 2.8 0.15 12.2 1.8 1.4 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL IFRD PF05004.8 EMC76889.1 - 2.6e-119 397.8 5.9 3.1e-119 397.6 4.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 EMC76889.1 - 3.5e-27 94.3 0.7 3.5e-27 94.3 0.5 2.0 2 0 0 2 2 2 1 Interferon-related protein conserved region HEAT PF02985.17 EMC76889.1 - 0.038 14.0 0.4 7.4 6.9 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat zf-C2H2_2 PF12756.2 EMC76890.1 - 2e-44 149.8 24.4 3.2e-24 84.9 4.4 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMC76890.1 - 5.2e-05 23.2 2.8 5.2e-05 23.2 1.9 3.9 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMC76890.1 - 0.00061 19.9 1.8 0.00061 19.9 1.2 5.6 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-BED PF02892.10 EMC76890.1 - 0.0042 16.8 1.3 0.0042 16.8 0.9 4.4 5 0 0 5 5 4 1 BED zinc finger zf-C2H2_4 PF13894.1 EMC76890.1 - 0.017 15.4 0.7 0.017 15.4 0.5 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger PyrI_C PF02748.10 EMC76890.1 - 0.034 13.5 0.4 0.034 13.5 0.3 4.1 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.2 EMC76890.1 - 0.062 13.5 1.2 0.062 13.5 0.9 3.8 4 1 0 4 4 3 0 Zinc-finger of C2H2 type YokU PF14122.1 EMC76890.1 - 0.071 12.8 0.0 0.071 12.8 0.0 2.9 4 0 0 4 4 4 0 YokU-like protein BIR PF00653.16 EMC76890.1 - 0.098 13.0 12.5 1 9.8 0.1 5.3 5 0 0 5 5 5 0 Inhibitor of Apoptosis domain zf-H2C2_5 PF13909.1 EMC76890.1 - 0.19 12.0 0.2 0.19 12.0 0.1 4.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-DBF PF07535.7 EMC76890.1 - 0.19 11.4 13.7 0.56 9.9 1.0 3.1 3 0 0 3 3 3 0 DBF zinc finger Ded_cyto PF06920.8 EMC76891.1 - 5.3e-51 172.4 0.5 9.5e-51 171.6 0.3 1.4 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EMC76891.1 - 8.2e-50 168.9 0.0 5.8e-49 166.2 0.0 2.5 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.23 EMC76891.1 - 0.0008 18.7 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC76891.1 - 0.00088 18.7 0.1 0.0027 17.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EMC76891.1 - 0.0025 17.3 0.0 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain LRR_8 PF13855.1 EMC76892.1 - 8.2e-44 147.1 45.5 1.4e-12 47.1 3.7 6.8 2 1 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EMC76892.1 - 2.5e-22 78.0 48.4 4.1e-05 23.0 0.3 7.7 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC76892.1 - 9.7e-21 73.8 0.1 2.8e-08 33.5 0.0 3.5 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) I-set PF07679.11 EMC76892.1 - 4.3e-13 48.9 0.0 2.8e-12 46.3 0.0 2.1 1 1 1 2 2 2 1 Immunoglobulin I-set domain LRR_1 PF00560.28 EMC76892.1 - 1.9e-09 36.2 34.8 1.7 8.9 0.0 11.9 11 1 1 12 12 12 4 Leucine Rich Repeat Ig_3 PF13927.1 EMC76892.1 - 4.8e-08 33.3 0.5 2e-07 31.4 0.3 2.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC76892.1 - 7.2e-08 32.4 0.1 2.5e-07 30.7 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC76892.1 - 1.7e-07 31.2 0.0 4.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 EMC76892.1 - 1.8e-07 31.1 0.1 3.9e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.12 EMC76892.1 - 0.00012 21.8 0.2 0.00042 20.1 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 EMC76892.1 - 0.00031 20.3 15.3 0.15 11.6 1.1 4.3 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 EMC76892.1 - 0.00073 19.3 25.4 5.2 7.7 0.1 9.8 9 1 1 10 10 10 1 Leucine rich repeat LRRCT PF01463.19 EMC76892.1 - 0.047 13.9 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain UPF0102 PF02021.12 EMC76892.1 - 0.063 13.2 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0102 LRRNT PF01462.13 EMC76892.1 - 0.19 11.2 7.1 0.036 13.5 0.6 3.1 4 0 0 4 4 3 0 Leucine rich repeat N-terminal domain COPIIcoated_ERV PF07970.7 EMC76893.1 - 6e-84 281.1 1.1 7.5e-84 280.7 0.7 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMC76893.1 - 3.4e-15 55.8 0.0 7.8e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glyco_transf_29 PF00777.13 EMC76894.1 - 4.3e-14 52.3 0.0 4.4e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF2574 PF10836.3 EMC76895.1 - 0.18 11.5 1.1 0.26 10.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Copine PF07002.11 EMC76896.1 - 1.3e-61 206.5 0.0 4.4e-61 204.8 0.0 1.8 2 0 0 2 2 2 1 Copine C2 PF00168.25 EMC76896.1 - 2.6e-21 75.2 0.0 1.6e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EMC76896.1 - 2.7e-10 40.4 0.0 4.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EMC76896.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF3682 PF12446.3 EMC76897.1 - 2.9 8.1 9.2 3.4 7.9 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RRM_6 PF14259.1 EMC76898.1 - 5.2e-47 157.6 2.6 2.6e-10 40.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC76898.1 - 7.5e-30 102.3 2.2 6.6e-09 35.2 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC76898.1 - 1.8e-11 43.7 0.4 0.029 14.2 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.14 EMC76899.1 - 5.1e-93 311.7 0.0 5.9e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC76899.1 - 1e-10 41.2 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMC76899.1 - 0.0008 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EMC76899.1 - 0.014 13.9 0.0 0.023 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain RRM_1 PF00076.17 EMC76900.1 - 8e-43 143.9 0.0 8.2e-25 86.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC76900.1 - 8.5e-32 108.9 0.2 3.3e-16 59.0 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC76900.1 - 2.4e-26 91.3 0.0 1.6e-11 43.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EMC76900.1 - 1.2e-23 83.1 1.7 1.8e-22 79.3 1.2 2.4 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.1 EMC76900.1 - 0.14 11.9 0.0 4.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RhoGAP PF00620.22 EMC76902.1 - 4.2e-26 91.3 0.0 1.7e-25 89.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.12 EMC76902.1 - 6.8e-18 64.6 0.4 1.2e-16 60.6 0.1 2.7 1 1 1 2 2 2 1 MyTH4 domain WW PF00397.21 EMC76902.1 - 2.7e-06 27.1 3.8 9.1e-06 25.4 2.6 2.0 1 0 0 1 1 1 1 WW domain DUF551 PF04448.7 EMC76902.1 - 0.0074 17.0 0.1 0.037 14.7 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF551) DUF3776 PF12618.3 EMC76903.1 - 7.1e-13 49.0 17.3 7.1e-13 49.0 12.0 5.1 5 1 0 5 5 5 1 Protein of unknown function (DUF3776) PHD PF00628.24 EMC76903.1 - 7.7e-07 28.7 12.5 3.9e-06 26.4 8.7 2.4 1 0 0 1 1 1 1 PHD-finger DUF4537 PF15057.1 EMC76903.1 - 3.1e-05 23.7 0.0 0.0001 22.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.5 EMC76903.1 - 0.0015 18.2 0.2 0.13 12.0 0.1 2.8 2 0 0 2 2 2 1 Fungal Rad9-like Rad53-binding Tudor-knot PF11717.3 EMC76903.1 - 0.0021 17.7 2.4 0.0058 16.3 0.9 2.4 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 EMC76903.1 - 1.6 9.2 10.5 0.33 11.3 3.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type SH2 PF00017.19 EMC76904.1 - 5.9e-21 74.0 0.0 8.4e-21 73.5 0.0 1.2 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 EMC76904.1 - 2.6e-05 23.6 0.0 7.7e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC76904.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC76904.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Ndr PF03096.9 EMC76905.1 - 1.2e-125 417.6 0.0 1.4e-125 417.4 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 EMC76905.1 - 3.9e-15 56.3 0.0 5.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC76905.1 - 7.2e-06 25.7 0.0 3.2e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Torsin PF06309.6 EMC76908.1 - 9.1e-39 132.2 0.1 4e-38 130.1 0.0 1.9 2 0 0 2 2 2 1 Torsin AAA_2 PF07724.9 EMC76908.1 - 0.00026 20.9 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EMC76908.1 - 0.0058 16.8 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EMC76908.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EMC76908.1 - 0.021 15.6 0.0 0.043 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EMC76908.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EMC76908.1 - 0.094 12.8 0.1 5.3 7.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EMC76908.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain SH2 PF00017.19 EMC76909.1 - 2.3e-15 56.1 0.1 4.4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.14 EMC76909.1 - 1.6e-13 50.8 0.0 2.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain Mur_ligase_M PF08245.7 EMC76910.1 - 0.093 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Mur ligase middle domain ADK PF00406.17 EMC76911.1 - 2.1e-55 186.7 0.1 2.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EMC76911.1 - 1.2e-08 35.7 0.0 1.9e-08 35.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC76911.1 - 1.7e-08 34.4 0.0 3.7e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC76911.1 - 1.1e-07 32.2 0.1 2e-07 31.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMC76911.1 - 1.4e-06 27.8 0.1 0.033 13.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 EMC76911.1 - 0.00081 19.5 0.1 0.011 15.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC76911.1 - 0.0019 17.2 0.3 0.0063 15.6 0.2 1.9 1 1 0 1 1 1 1 Zeta toxin MobB PF03205.9 EMC76911.1 - 0.03 14.0 0.7 0.13 11.9 0.1 2.2 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B dNK PF01712.14 EMC76911.1 - 0.044 13.6 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_19 PF13245.1 EMC76911.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EMC76911.1 - 0.08 12.6 0.3 0.23 11.1 0.0 1.9 2 1 1 3 3 3 0 NTPase ABC_tran PF00005.22 EMC76911.1 - 0.13 12.5 0.1 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Lipoprotein_16 PF03923.8 EMC76911.1 - 0.13 11.5 0.1 3.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized lipoprotein Glyco_transf_29 PF00777.13 EMC76912.1 - 1.4e-35 122.7 0.0 1.6e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DPM2 PF07297.7 EMC76913.1 - 1.2e-32 111.9 6.5 1.3e-32 111.8 4.5 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EMC76913.1 - 0.00015 21.3 6.9 0.00018 21.1 4.8 1.1 1 0 0 1 1 1 1 PIG-P TMEM154 PF15102.1 EMC76913.1 - 0.066 12.9 0.2 0.098 12.3 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family UPF0104 PF03706.8 EMC76913.1 - 0.074 12.3 4.5 0.086 12.1 3.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) RDD PF06271.7 EMC76913.1 - 0.16 11.9 5.9 0.19 11.6 4.1 1.1 1 0 0 1 1 1 0 RDD family DUF1422 PF07226.6 EMC76913.1 - 0.43 10.3 3.3 0.57 9.9 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1422) EphA2_TM PF14575.1 EMC76913.1 - 0.44 10.9 3.0 0.73 10.2 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FixQ PF05545.6 EMC76913.1 - 0.58 9.8 0.1 0.58 9.8 0.1 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1625 PF07787.7 EMC76913.1 - 0.69 9.1 6.6 0.97 8.6 4.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) DUF3043 PF11241.3 EMC76913.1 - 1.1 8.8 2.9 0.67 9.5 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) DUF3278 PF11683.3 EMC76913.1 - 1.7 8.6 4.2 2.8 7.9 2.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) zf-DHHC PF01529.15 EMC76913.1 - 2.1 7.6 6.3 2.4 7.5 4.4 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2207 PF09972.4 EMC76913.1 - 2.4 6.6 4.8 2.4 6.6 3.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VirB3 PF05101.8 EMC76913.1 - 8.4 6.4 6.8 25 4.9 1.0 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein NT-C2 PF10358.4 EMC76914.1 - 5.6e-31 106.9 0.2 1.6e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Myb_DNA-bind_5 PF13873.1 EMC76915.1 - 3.3e-24 84.5 1.1 3.3e-24 84.5 0.8 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EMC76915.1 - 0.00086 19.4 0.4 0.0024 18.0 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF885 PF05960.6 EMC76915.1 - 0.089 11.9 4.2 0.04 13.0 1.4 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Myb_DNA-bind_4 PF13837.1 EMC76915.1 - 0.13 12.4 0.6 0.28 11.3 0.0 1.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lipoprotein_7 PF01540.11 EMC76915.1 - 0.21 10.6 1.3 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 Adhesin lipoprotein DUF3450 PF11932.3 EMC76915.1 - 0.23 10.6 10.3 0.045 12.9 4.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Mito_carr PF00153.22 EMC76916.1 - 4.1e-75 247.5 2.8 1.9e-25 88.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EMC76916.1 - 6.2e-15 55.0 2.4 1.2e-10 41.3 0.2 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC76916.1 - 5.6e-14 50.3 2.5 0.0012 17.9 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EMC76916.1 - 2.2e-11 42.6 2.8 0.00034 20.2 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EMC76916.1 - 4.1e-10 39.1 1.5 0.0012 18.4 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC76916.1 - 8.3e-08 31.2 0.9 0.0077 15.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 EMC76916.1 - 0.00019 21.0 0.4 2.2 7.9 0.0 3.7 3 1 1 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 EMC76916.1 - 0.00058 19.8 0.9 0.0019 18.2 0.6 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region UBN2 PF14223.1 EMC76916.1 - 0.023 14.5 0.1 0.79 9.5 0.0 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type EF-hand_4 PF12763.2 EMC76916.1 - 0.036 13.7 2.4 0.45 10.2 0.3 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC76916.1 - 0.13 12.1 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain ApoM PF11032.3 EMC76917.1 - 9.5e-14 51.3 0.0 1.1e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein M (ApoM) Lipocalin PF00061.18 EMC76917.1 - 2.4e-07 30.8 0.0 3.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family LRR_6 PF13516.1 EMC76918.1 - 8.4e-05 22.2 0.9 0.46 10.7 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 EMC76918.1 - 0.032 13.8 0.1 1.6 8.4 0.0 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC76918.1 - 0.14 12.2 0.3 42 4.7 0.2 3.3 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 EMC76918.1 - 0.16 11.7 0.3 1.9 8.2 0.1 2.4 2 1 0 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 EMC76918.1 - 0.2 11.9 2.1 36 5.1 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat VPS28 PF03997.7 EMC76919.1 - 2e-46 157.9 0.2 6.5e-46 156.3 0.1 1.7 1 1 0 1 1 1 1 VPS28 protein HTH_41 PF14502.1 EMC76919.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain KRAB PF01352.22 EMC76921.1 - 6.7e-10 38.2 5.0 1.8e-09 36.9 3.5 1.6 1 1 0 1 1 1 1 KRAB box zf-H2C2_2 PF13465.1 EMC76922.1 - 8e-107 344.7 105.2 2e-08 34.0 0.3 16.5 17 0 0 17 17 16 16 Zinc-finger double domain zf-C2H2 PF00096.21 EMC76922.1 - 1.3e-66 217.0 143.3 4.6e-07 29.8 0.4 17.5 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC76922.1 - 1.5e-37 125.1 116.9 0.00031 20.8 3.8 17.2 17 0 0 17 17 17 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC76922.1 - 5.3e-19 67.8 63.4 0.023 14.8 0.5 15.7 16 0 0 16 16 15 8 Zinc-finger double-stranded RNA-binding KRAB PF01352.22 EMC76922.1 - 9.6e-19 66.5 0.1 1.6e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 KRAB box zf-LYAR PF08790.6 EMC76922.1 - 8.3e-16 57.3 86.3 0.038 13.6 0.2 14.3 14 0 0 14 14 14 9 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.5 EMC76922.1 - 5.3e-10 39.0 77.0 0.23 11.4 1.7 13.3 6 4 8 14 14 14 11 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMC76922.1 - 1.4e-09 37.5 109.8 0.00041 20.1 0.4 16.1 16 1 0 16 16 15 7 C2H2-type zinc finger zf-trcl PF13451.1 EMC76922.1 - 2.4e-08 33.4 66.1 2.4 7.8 0.1 13.8 14 0 0 14 14 14 6 Probable zinc-binding domain TFIIS_C PF01096.13 EMC76922.1 - 6.4e-06 25.7 67.4 9.2 5.9 1.9 14.3 14 0 0 14 14 14 0 Transcription factor S-II (TFIIS) FYDLN_acid PF09538.5 EMC76922.1 - 0.0015 19.0 40.7 21 5.7 0.0 12.4 5 4 5 10 10 10 0 Protein of unknown function (FYDLN_acid) LIM PF00412.17 EMC76922.1 - 0.0021 18.1 87.3 1.5 8.9 1.6 14.0 8 4 6 14 14 14 5 LIM domain BolA PF01722.13 EMC76922.1 - 0.008 16.1 19.6 12 5.9 0.1 7.4 3 2 3 7 7 7 0 BolA-like protein BHD_1 PF10403.4 EMC76922.1 - 0.024 14.1 2.8 56 3.3 0.0 5.8 5 2 2 7 7 7 0 Rad4 beta-hairpin domain 1 YhfH PF14149.1 EMC76922.1 - 0.21 11.3 71.0 21 5.0 0.1 13.9 14 0 0 14 14 14 0 YhfH-like protein C1_4 PF07975.7 EMC76922.1 - 0.21 11.5 72.5 0.079 12.9 0.4 10.1 5 2 4 11 11 11 0 TFIIH C1-like domain DUF1635 PF07795.6 EMC76922.1 - 0.89 8.8 5.9 74 2.6 0.0 5.5 5 4 2 7 7 7 0 Protein of unknown function (DUF1635) PAR1 PF06521.6 EMC76922.1 - 1.9 8.0 9.3 24 4.4 0.1 4.7 3 1 1 5 5 5 0 PAR1 protein Med13_C PF06333.7 EMC76923.1 - 1.4e-133 445.5 0.0 1.4e-133 445.5 0.0 2.6 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EMC76923.1 - 2.6e-73 247.0 0.0 2.6e-73 247.0 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal DUF2054 PF10218.4 EMC76924.1 - 5.7e-52 175.0 19.0 8.5e-52 174.5 13.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) WD40 PF00400.27 EMC76925.1 - 4e-08 32.8 12.9 0.051 13.4 0.1 5.8 7 1 0 7 7 7 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMC76925.1 - 0.016 14.9 0.0 0.086 12.6 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Transglut_core2 PF13369.1 EMC76926.1 - 3e-41 140.4 0.0 5e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.6 EMC76926.1 - 7.8e-28 96.3 0.3 2.2e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like TPR_16 PF13432.1 EMC76926.1 - 0.013 16.2 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NO_synthase PF02898.10 EMC76927.1 - 8.2e-218 722.3 0.1 1.5e-217 721.5 0.0 1.4 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.15 EMC76927.1 - 1.7e-79 266.3 0.2 8.3e-79 264.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EMC76927.1 - 5.3e-31 107.5 0.9 8.7e-30 103.5 0.1 2.7 2 1 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EMC76927.1 - 2.7e-21 76.1 0.0 9.2e-21 74.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PDZ PF00595.19 EMC76927.1 - 2.5e-16 59.6 0.0 5.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC76927.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.12 EMC76928.1 - 7.3e-40 136.6 0.0 1.4e-39 135.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC76928.1 - 1e-38 133.0 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.17 EMC76928.1 - 2.7e-05 23.8 12.1 5.5e-05 22.8 8.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.9 EMC76928.1 - 0.024 13.6 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC76928.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EMC76928.1 - 0.045 12.7 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EMC76928.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rep_fac_C PF08542.6 EMC76929.1 - 2.9e-23 81.6 0.1 5e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EMC76929.1 - 1.1e-15 57.9 0.0 1.9e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMC76929.1 - 3.9e-14 52.6 0.0 2e-11 43.8 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_22 PF13401.1 EMC76929.1 - 2.5e-07 30.9 0.2 0.0052 16.9 0.0 2.9 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EMC76929.1 - 8.5e-07 28.6 0.0 2.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMC76929.1 - 1.2e-05 25.4 0.0 4.1e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EMC76929.1 - 2.5e-05 23.9 0.0 0.00081 19.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EMC76929.1 - 2.7e-05 24.0 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMC76929.1 - 8.4e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EMC76929.1 - 0.00013 21.4 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 EMC76929.1 - 0.00046 19.9 0.1 0.0028 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EMC76929.1 - 0.00053 18.8 0.0 0.071 11.7 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 EMC76929.1 - 0.00087 18.7 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EMC76929.1 - 0.00098 18.6 0.1 0.031 13.7 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EMC76929.1 - 0.0023 17.3 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.1 EMC76929.1 - 0.0028 17.2 0.0 0.16 11.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EMC76929.1 - 0.0028 16.9 0.1 0.16 11.2 0.0 2.4 1 1 0 2 2 2 1 PhoH-like protein RuvB_N PF05496.7 EMC76929.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMC76929.1 - 0.0059 15.3 0.0 0.082 11.6 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EMC76929.1 - 0.0099 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 EMC76929.1 - 0.011 15.1 0.1 3.4 7.0 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 EMC76929.1 - 0.042 13.0 0.0 0.6 9.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 EMC76929.1 - 0.065 12.0 0.0 0.6 8.8 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_3 PF07726.6 EMC76929.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EMC76929.1 - 0.096 12.5 0.0 1.2 8.9 0.0 2.4 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit WD40 PF00400.27 EMC76930.1 - 1.7e-24 84.7 2.5 4.4e-09 35.8 0.1 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat SOCS_box PF07525.11 EMC76930.1 - 2e-11 43.5 1.6 4.5e-11 42.4 1.1 1.6 1 0 0 1 1 1 1 SOCS box RasGAP PF00616.14 EMC76931.1 - 1.5e-49 168.3 0.0 1.9e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EMC76931.1 - 1.7e-36 123.9 0.0 4.9e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain EpoR_lig-bind PF09067.5 EMC76932.1 - 0.2 11.6 4.6 0.18 11.7 2.6 1.5 1 1 0 1 1 1 0 Erythropoietin receptor, ligand binding Filament PF00038.16 EMC76934.1 - 2.2e-38 132.5 15.5 2.4e-38 132.3 10.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein GBP_C PF02841.9 EMC76934.1 - 0.00094 18.4 9.1 0.00097 18.4 6.3 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain IncA PF04156.9 EMC76934.1 - 0.0043 16.6 12.0 0.0055 16.3 8.3 1.2 1 0 0 1 1 1 1 IncA protein DUF4515 PF14988.1 EMC76934.1 - 0.015 14.9 12.1 0.049 13.3 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) TMEM51 PF15345.1 EMC76934.1 - 0.031 13.9 1.7 0.034 13.8 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Gp58 PF07902.6 EMC76934.1 - 0.043 12.0 1.7 0.049 11.8 1.2 1.1 1 0 0 1 1 1 0 gp58-like protein Mnd1 PF03962.10 EMC76934.1 - 0.047 13.3 7.9 0.058 13.0 5.5 1.1 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 EMC76934.1 - 0.049 12.5 7.5 0.058 12.3 5.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HHH_8 PF14716.1 EMC76934.1 - 0.1 12.7 2.9 1.2 9.3 0.2 2.7 2 1 1 3 3 3 0 Helix-hairpin-helix domain COG2 PF06148.6 EMC76934.1 - 0.11 12.3 6.5 0.45 10.3 1.0 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4081 PF13312.1 EMC76934.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4081) FliJ PF02050.11 EMC76934.1 - 0.13 12.2 16.3 1.4 8.9 4.6 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein Mod_r PF07200.8 EMC76934.1 - 0.16 11.8 9.1 0.11 12.3 4.0 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Membralin PF09746.4 EMC76934.1 - 0.18 10.8 2.1 0.19 10.7 1.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein Selenoprotein_S PF06936.6 EMC76934.1 - 0.23 10.9 5.4 0.29 10.6 3.7 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Phage_GP20 PF06810.6 EMC76934.1 - 0.27 10.6 7.5 0.55 9.6 5.2 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 EMC76934.1 - 0.29 10.8 11.0 0.49 10.1 1.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2968 PF11180.3 EMC76934.1 - 0.32 10.3 11.3 0.39 10.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4094 PF13334.1 EMC76934.1 - 0.33 11.3 3.7 0.5 10.7 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Ly49 PF08391.5 EMC76934.1 - 0.42 10.7 2.1 0.59 10.2 1.2 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4200 PF13863.1 EMC76934.1 - 0.5 10.3 11.6 0.6 10.0 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Ax_dynein_light PF10211.4 EMC76934.1 - 0.5 10.1 10.4 0.47 10.2 4.9 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.1 EMC76934.1 - 0.56 10.6 10.5 7.1 7.1 1.3 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4110 PF13422.1 EMC76934.1 - 0.73 9.7 5.7 0.27 11.0 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DUF4047 PF13256.1 EMC76934.1 - 0.77 9.7 4.5 1.1 9.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF342 PF03961.8 EMC76934.1 - 1.2 7.4 5.6 1.3 7.3 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 EMC76934.1 - 1.9 7.5 6.1 2 7.5 4.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.3 EMC76934.1 - 2.2 8.1 9.5 11 5.9 1.2 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Bap31 PF05529.7 EMC76934.1 - 2.3 7.6 7.2 0.72 9.2 1.0 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Pox_A_type_inc PF04508.7 EMC76934.1 - 2.4 8.1 5.9 50 4.0 0.2 3.8 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Tup_N PF08581.5 EMC76934.1 - 2.4 8.3 10.1 1.9 8.7 5.0 2.2 1 1 1 2 2 2 0 Tup N-terminal V-ATPase_G PF03179.10 EMC76934.1 - 2.8 8.2 8.8 2.4 8.4 4.0 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit CENP-Q PF13094.1 EMC76934.1 - 3 7.8 13.6 6.7 6.7 9.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OEP PF02321.13 EMC76934.1 - 3 7.3 13.8 4.7 6.7 9.6 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein DivIC PF04977.10 EMC76934.1 - 3.2 7.2 10.6 1.8 8.1 2.0 2.6 1 1 2 3 3 3 0 Septum formation initiator Spc24 PF08286.6 EMC76934.1 - 6.4 6.4 9.1 3.7 7.2 3.7 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 EMC76934.1 - 6.8 7.0 8.9 3.9 7.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) OmpH PF03938.9 EMC76934.1 - 8.6 6.2 13.0 38 4.1 9.0 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NIPSNAP PF07978.8 EMC76935.1 - 5.7e-33 112.9 0.4 8.3e-33 112.4 0.3 1.2 1 0 0 1 1 1 1 NIPSNAP EF-hand_1 PF00036.27 EMC76936.1 - 5.4e-19 65.9 0.9 7.8e-10 37.3 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EMC76936.1 - 1.5e-14 52.5 2.6 1.3e-06 27.4 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC76936.1 - 2.4e-14 51.8 0.5 6.5e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EMC76936.1 - 2.4e-14 53.1 0.2 3.5e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC76936.1 - 6.2e-14 51.3 1.4 4.4e-11 42.2 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 EMC76936.1 - 0.004 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC76936.1 - 0.0073 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region zf-U1 PF06220.7 EMC76937.1 - 6.2e-08 32.0 4.1 1.2e-07 31.1 2.8 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-CCCH PF00642.19 EMC76937.1 - 9.6e-08 31.5 1.6 1.5e-07 30.9 1.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4239 PF14023.1 EMC76937.1 - 0.078 12.3 0.1 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF4127 PF13552.1 EMC76937.1 - 0.12 10.7 0.1 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) zf-C2H2_jaz PF12171.3 EMC76937.1 - 0.22 11.6 7.6 1 9.6 5.3 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Acyl-CoA_dh_1 PF00441.19 EMC76939.1 - 2e-28 99.3 0.7 2e-28 99.3 0.5 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC76939.1 - 4.1e-10 39.0 0.4 8.6e-10 37.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC76939.1 - 1.3e-08 35.2 0.7 6.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HORMA PF02301.13 EMC76940.1 - 1.1e-49 168.8 0.0 1.5e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 HORMA domain LIF_OSM PF01291.12 EMC76941.1 - 7.4e-26 90.9 0.4 8.3e-26 90.8 0.3 1.0 1 0 0 1 1 1 1 LIF / OSM family PqqD PF05402.7 EMC76941.1 - 0.061 13.3 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) CcmH PF03918.9 EMC76941.1 - 0.085 11.8 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein ACT_7 PF13840.1 EMC76942.1 - 5.6e-14 51.3 0.0 9.3e-14 50.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF2342 PF10103.4 EMC76942.1 - 0.07 12.0 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2342) RabGAP-TBC PF00566.13 EMC76943.1 - 5.9e-55 186.0 0.0 8.6e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CRAL_TRIO PF00650.15 EMC76945.1 - 1.8e-40 138.0 0.0 2.7e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 EMC76945.1 - 1.1e-09 38.5 0.4 8.8e-06 25.9 0.0 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.1 EMC76945.1 - 3.5e-07 30.2 0.0 6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC76945.1 - 4.1e-07 30.0 0.3 1.3e-06 28.4 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain L71 PF02448.10 EMC76945.1 - 0.092 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 L71 family MTP18 PF10558.4 EMC76946.1 - 7.9e-09 35.5 0.0 8.6e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Gal-3-0_sulfotr PF06990.6 EMC76947.1 - 1.2e-165 551.0 0.2 1.5e-165 550.7 0.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Pescadillo_N PF06732.6 EMC76948.1 - 3.5e-131 436.5 0.8 3.5e-131 436.5 0.6 2.6 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EMC76948.1 - 2.6e-08 33.9 0.0 1.7e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Astro_capsid PF03115.9 EMC76948.1 - 0.055 11.7 5.2 0.077 11.2 3.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 EMC76948.1 - 0.19 10.1 21.4 0.38 9.1 14.9 1.5 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 EMC76948.1 - 0.32 10.6 17.8 1 9.0 12.3 1.8 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 EMC76948.1 - 2.6 5.9 20.3 5.4 4.9 14.1 1.6 1 0 0 1 1 1 0 CDC45-like protein Cobalamin_bind PF01122.14 EMC76949.1 - 6.6e-72 241.8 0.0 8e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein IQ PF00612.22 EMC76950.1 - 4.1e-07 29.0 2.8 2.5e-06 26.6 0.6 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif GAS PF13851.1 EMC76950.1 - 0.00053 19.2 6.2 0.00053 19.2 4.3 2.8 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding RNA_pol_Rpb1_6 PF04992.9 EMC76950.1 - 0.61 9.8 8.0 0.1 12.3 1.6 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 Oxysterol_BP PF01237.13 EMC76951.1 - 5e-24 84.4 0.1 5.8e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein LRR_8 PF13855.1 EMC76952.1 - 6e-41 138.0 39.1 4.1e-13 48.8 5.0 4.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EMC76952.1 - 1.2e-16 59.8 34.6 1.5e-05 24.5 3.0 6.0 4 1 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC76952.1 - 3.1e-15 56.0 0.0 1.5e-09 37.6 0.0 2.6 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC76952.1 - 2.8e-11 41.8 33.1 0.028 14.4 0.1 10.1 10 0 0 10 10 10 4 Leucine Rich Repeat LRRNT PF01462.13 EMC76952.1 - 0.001 18.5 1.8 0.001 18.5 1.3 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 EMC76952.1 - 0.0014 18.1 6.1 0.041 13.4 0.9 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 EMC76952.1 - 0.82 10.1 35.6 3.3 8.3 0.1 8.7 10 0 0 10 10 10 0 Leucine rich repeat LRR_6 PF13516.1 EMC76952.1 - 1.6 9.0 27.2 4.4 7.6 0.4 8.1 7 1 1 8 8 8 0 Leucine Rich repeat Pro_dh PF01619.13 EMC76953.1 - 3e-63 213.7 0.3 3.8e-63 213.3 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DGCR6 PF07324.6 EMC76954.1 - 1.1e-51 175.1 5.9 1.2e-51 175.0 4.1 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein MEKHLA PF08670.6 EMC76954.1 - 0.025 14.1 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 MEKHLA domain DUF2458 PF10454.4 EMC76954.1 - 0.054 13.3 2.8 0.089 12.6 1.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) AA_permease_2 PF13520.1 EMC76955.1 - 2.2e-48 164.8 35.5 2.2e-48 164.8 24.6 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 EMC76955.1 - 1.4e-39 135.7 43.3 1.8e-39 135.4 23.1 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.1 EMC76955.1 - 8.7e-21 73.5 8.5 8.7e-21 73.5 5.9 4.0 4 0 0 4 4 4 1 C-terminus of AA_permease IncA PF04156.9 EMC76955.1 - 1.9 8.0 0.0 1.9 8.0 0.0 4.3 4 0 0 4 4 4 0 IncA protein P2X_receptor PF00864.14 EMC76956.1 - 1.1e-91 307.3 0.1 1.3e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.16 EMC76956.1 - 0.062 13.2 2.2 0.11 12.4 0.5 2.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Transmemb_17 PF09799.4 EMC76957.1 - 1.4e-17 63.9 2.8 1.5e-17 63.8 1.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein Pyr_redox_2 PF07992.9 EMC76958.1 - 3.1e-36 125.1 0.0 1.3e-35 123.1 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC76958.1 - 1.8e-18 66.6 3.6 1.3e-14 54.3 0.4 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EMC76958.1 - 3.5e-16 58.5 0.2 8.6e-16 57.2 0.2 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 EMC76958.1 - 1e-10 41.0 0.7 0.00038 19.4 0.1 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC76958.1 - 6.9e-10 39.3 1.0 4.5e-05 23.5 0.0 3.1 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC76958.1 - 7.8e-09 34.4 2.3 0.003 16.0 0.1 4.0 3 1 1 4 4 4 2 HI0933-like protein Reductase_C PF14759.1 EMC76958.1 - 1e-07 32.1 0.0 2.7e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_8 PF13450.1 EMC76958.1 - 1.3e-07 31.5 0.2 0.00033 20.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Rieske_2 PF13806.1 EMC76958.1 - 1.4e-07 31.1 0.0 6.6e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Lycopene_cycl PF05834.7 EMC76958.1 - 2.2e-06 26.8 1.3 0.048 12.5 0.0 3.3 2 2 1 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMC76958.1 - 7.6e-06 25.0 4.3 0.0014 17.5 0.0 3.8 3 1 1 4 4 4 1 FAD binding domain FAD_binding_3 PF01494.14 EMC76958.1 - 1.4e-05 24.2 1.1 0.0015 17.6 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EMC76958.1 - 0.0003 19.9 1.0 0.18 10.8 0.0 2.9 3 0 0 3 3 3 2 Thi4 family TrkA_N PF02254.13 EMC76958.1 - 0.00067 19.6 0.1 0.6 10.1 0.0 2.9 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.1 EMC76958.1 - 0.00073 19.3 2.0 1.1 8.9 0.0 3.4 2 2 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.17 EMC76958.1 - 0.00079 18.3 2.2 0.93 8.2 0.0 3.5 3 1 1 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.1 EMC76958.1 - 0.00095 18.1 0.0 0.0078 15.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EMC76958.1 - 0.0027 17.8 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 EMC76958.1 - 0.0034 16.9 0.0 0.014 14.9 0.0 2.0 3 0 0 3 3 3 1 Malic enzyme, NAD binding domain NAD_binding_7 PF13241.1 EMC76958.1 - 0.0097 16.1 1.2 1.5 9.1 0.0 3.1 2 1 0 3 3 3 1 Putative NAD(P)-binding DUF1188 PF06690.6 EMC76958.1 - 0.024 13.7 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) ThiF PF00899.16 EMC76958.1 - 0.036 13.8 4.4 0.28 11.0 0.0 3.0 3 0 0 3 3 3 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EMC76958.1 - 0.079 12.3 0.8 2.6 7.3 0.1 2.8 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CARD PF00619.16 EMC76959.1 - 8.1e-16 57.6 2.7 1.3e-15 57.0 1.9 1.3 1 0 0 1 1 1 1 Caspase recruitment domain ubiquitin PF00240.18 EMC76959.1 - 5.6e-08 32.0 0.0 8.5e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC76959.1 - 0.00038 20.0 0.1 0.00096 18.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Sec23_helical PF04815.10 EMC76959.1 - 0.14 11.5 0.5 23 4.4 0.0 3.0 4 0 0 4 4 4 0 Sec23/Sec24 helical domain PNTB PF02233.11 EMC76960.1 - 2.6e-212 705.6 16.9 2.6e-212 705.6 11.7 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EMC76960.1 - 2.1e-53 180.3 1.1 4.2e-53 179.3 0.8 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EMC76960.1 - 2.6e-46 156.9 0.6 1.2e-45 154.8 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EMC76960.1 - 2.6e-32 110.8 3.2 2.6e-32 110.8 2.2 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EMC76960.1 - 0.0037 16.4 0.8 0.76 8.9 0.1 2.9 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EMC76960.1 - 0.0072 15.8 0.9 0.049 13.1 0.2 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ComX PF05952.7 EMC76960.1 - 0.06 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacillus competence pheromone ComX MIF4G PF02854.14 EMC76961.1 - 1.1e-30 106.6 0.0 1.5e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.10 EMC76961.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF457 PF04307.9 EMC76962.1 - 0.0014 18.0 10.8 0.0025 17.1 7.5 1.5 1 1 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) HMG_CoA_synt_C PF08540.5 EMC76963.1 - 1.1e-128 428.6 0.6 1.4e-128 428.3 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EMC76963.1 - 3.4e-107 355.5 0.5 4.8e-107 355.0 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 EMC76963.1 - 0.00025 20.6 0.1 0.00063 19.3 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.20 EMC76964.1 - 2.8e-70 236.4 0.0 4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC76964.1 - 6.5e-40 136.8 0.0 9.3e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC76964.1 - 4.3e-10 39.0 0.0 6.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC76964.1 - 0.00016 21.0 0.1 0.00028 20.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMC76964.1 - 0.0075 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.26 EMC76965.1 - 1.7e-24 85.9 0.5 4.7e-24 84.5 0.3 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC76965.1 - 3.7e-16 58.5 50.6 1e-07 31.9 4.5 7.6 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC76965.1 - 3.2e-14 52.3 55.0 0.012 15.9 0.1 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC76965.1 - 6.3e-12 44.9 56.1 0.022 15.0 3.7 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC76965.1 - 3.2e-08 33.4 41.6 0.00095 19.2 0.3 6.7 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC76965.1 - 6.6e-07 29.3 42.5 0.00064 19.8 0.6 6.7 7 0 0 7 7 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC76965.1 - 0.00064 19.5 39.0 0.28 11.1 0.1 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger SCFA_trans PF02667.9 EMC76965.1 - 0.25 10.0 2.3 0.39 9.4 1.6 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter zf-C2H2_2 PF12756.2 EMC76965.1 - 1.3 9.1 36.4 2.7 8.1 1.5 6.7 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.11 EMC76965.1 - 2.5 8.2 12.1 36 4.5 0.2 4.4 4 0 0 4 4 4 0 C1 domain zf-C2HC_2 PF13913.1 EMC76965.1 - 5 6.8 20.5 0.28 10.9 0.4 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-CHCC PF10276.4 EMC76965.1 - 5.5 6.9 8.2 4.4 7.2 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger domain SelP_N PF04592.9 EMC76966.1 - 1.7e-36 125.8 14.7 1.9e-36 125.6 10.2 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.17 EMC76966.1 - 0.041 12.8 9.5 0.047 12.6 6.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_A_type_inc PF04508.7 EMC76967.1 - 0.026 14.2 0.9 0.026 14.2 0.6 4.9 4 3 1 5 5 5 0 Viral A-type inclusion protein repeat TSC22 PF01166.13 EMC76967.1 - 0.028 14.3 0.8 0.028 14.3 0.5 4.5 2 1 1 4 4 4 0 TSC-22/dip/bun family DUF885 PF05960.6 EMC76967.1 - 0.58 9.2 11.0 0.69 8.9 7.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF3584 PF12128.3 EMC76967.1 - 1.2 6.3 26.0 1.5 6.0 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4140 PF13600.1 EMC76967.1 - 4.4 7.7 14.5 0.38 11.2 3.1 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Membralin PF09746.4 EMC76967.1 - 7.9 5.4 7.4 8.7 5.2 4.9 1.3 1 1 0 1 1 1 0 Tumour-associated protein GHBP PF12772.2 EMC76968.1 - 3.1e-104 348.5 7.5 4.1e-104 348.1 5.2 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.5 EMC76968.1 - 5.5e-13 48.8 2.3 5.5e-13 48.8 1.6 2.5 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 EMC76968.1 - 2.7e-06 27.4 0.2 6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC76968.1 - 0.027 14.6 1.0 0.092 12.9 0.7 1.9 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding HSNSD PF12062.3 EMC76970.1 - 4.1e-258 856.5 0.0 1e-257 855.2 0.0 1.6 2 0 0 2 2 2 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 EMC76970.1 - 1.3e-42 145.8 0.0 2.2e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC76970.1 - 0.0039 18.1 0.2 0.02 15.8 0.2 2.2 1 1 0 1 1 1 1 Sulfotransferase family UDPGT PF00201.13 EMC76971.1 - 1e-120 403.6 0.0 1.3e-120 403.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMC76971.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Imm20 PF15568.1 EMC76971.1 - 0.0058 16.5 0.1 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Immunity protein 20 Sulfatase PF00884.18 EMC76972.1 - 1.1e-46 159.5 0.1 1.5e-46 158.9 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMC76972.1 - 1.5e-05 25.3 0.0 3.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Pkinase PF00069.20 EMC76973.1 - 1.5e-68 230.8 0.0 2.4e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.5 EMC76973.1 - 3.9e-64 214.2 0.0 7.1e-64 213.4 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Pkinase_Tyr PF07714.12 EMC76973.1 - 2.1e-28 99.1 0.0 5e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4440 PF14534.1 EMC76973.1 - 1.1e-10 41.6 0.0 2.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EMC76973.1 - 4.1e-10 39.7 0.0 1.1e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain APH PF01636.18 EMC76973.1 - 0.0021 17.8 0.0 1.7 8.3 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family SnoaL_4 PF13577.1 EMC76973.1 - 0.0038 17.1 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EMC76973.1 - 0.0053 17.1 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain Kdo PF06293.9 EMC76973.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_3 PF08777.6 EMC76974.1 - 2.2e-28 98.1 0.1 2.2e-28 98.1 0.1 4.1 4 1 0 4 4 4 2 RNA binding motif La PF05383.12 EMC76974.1 - 3.2e-24 84.5 0.1 7.5e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EMC76974.1 - 4.6e-20 71.0 0.1 6.7e-17 60.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC76974.1 - 4.3e-17 61.8 0.0 8.7e-13 48.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC76974.1 - 1.1e-13 50.8 0.1 2.9e-09 36.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2439 PF10382.4 EMC76975.1 - 1.7e-18 66.5 0.2 5.5e-18 64.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) AAA_12 PF13087.1 EMC76976.1 - 4.2e-53 179.6 0.4 2.4e-52 177.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMC76976.1 - 5.6e-33 114.4 0.0 1.3e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain zf-GRF PF06839.7 EMC76976.1 - 3e-13 49.4 0.1 7.1e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 GRF zinc finger Viral_helicase1 PF01443.13 EMC76976.1 - 2.6e-08 33.6 1.3 0.014 14.8 0.0 3.7 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EMC76976.1 - 0.00052 19.6 0.0 0.071 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC76976.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EMC76976.1 - 0.0051 16.9 0.1 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 EMC76976.1 - 0.014 14.8 0.0 5.1 6.4 0.0 3.0 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Toxin_61 PF15538.1 EMC76976.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 61 FHA PF00498.21 EMC76977.1 - 4.6e-05 23.4 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 FHA domain DUF4605 PF15378.1 EMC76978.1 - 5.8e-28 96.3 5.4 5.8e-28 96.3 3.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4605) Peptidase_M1 PF01433.15 EMC76979.1 - 1.4e-140 468.8 0.8 2.2e-140 468.1 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMC76979.1 - 9.9e-46 156.4 1.6 1.8e-45 155.6 1.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMC76979.1 - 2e-20 73.1 0.0 5.2e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1570 PF07607.6 EMC76979.1 - 0.0015 18.4 0.1 0.0058 16.6 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1570) SKG6 PF08693.5 EMC76979.1 - 0.41 9.9 3.1 0.15 11.4 0.2 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ELO PF01151.13 EMC76980.1 - 9.6e-66 221.6 23.2 1.1e-65 221.4 16.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ldl_recept_b PF00058.12 EMC76981.1 - 2.6e-48 162.0 6.9 4.2e-10 39.7 0.0 7.9 8 0 0 8 8 8 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 EMC76981.1 - 1.6e-37 127.3 147.3 1.3e-08 34.7 4.6 11.5 11 0 0 11 11 11 8 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC76981.1 - 3.7e-29 99.9 80.9 2.2e-05 24.0 2.2 11.5 11 0 0 11 11 11 8 Complement Clr-like EGF-like EGF_CA PF07645.10 EMC76981.1 - 6.5e-22 77.2 139.4 3.3e-08 33.3 6.1 11.4 10 1 1 11 11 11 5 Calcium-binding EGF domain EGF PF00008.22 EMC76981.1 - 5.6e-17 61.3 111.8 8.5e-05 22.4 4.0 10.9 10 0 0 10 10 10 8 EGF-like domain EGF_3 PF12947.2 EMC76981.1 - 3.8e-16 58.7 122.7 7.8e-06 25.7 6.6 10.6 10 0 0 10 10 10 7 EGF domain SGL PF08450.7 EMC76981.1 - 1.1e-07 31.5 0.4 0.41 9.9 0.0 4.5 2 1 2 4 4 4 3 SMP-30/Gluconolaconase/LRE-like region 7tm_1 PF00001.16 EMC76982.1 - 6.8e-48 163.0 14.5 8.7e-48 162.6 10.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC76982.1 - 4.8e-12 45.5 12.0 6e-12 45.2 8.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srt PF10321.4 EMC76982.1 - 0.012 14.4 18.1 0.032 12.9 12.6 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt DUF3096 PF11295.3 EMC76982.1 - 0.13 11.7 2.3 0.18 11.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) DUF4117 PF13491.1 EMC76982.1 - 0.3 10.5 6.4 0.089 12.2 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) Gar1 PF04410.9 EMC76983.1 - 3.7e-42 143.4 0.1 3.7e-42 143.4 0.1 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Trypsin PF00089.21 EMC76984.1 - 2.6e-59 200.4 1.2 5.5e-59 199.4 0.8 1.6 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 EMC76984.1 - 9.3e-15 54.2 25.6 2e-09 37.1 7.1 4.0 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SRCR PF00530.13 EMC76984.1 - 6.6e-11 42.4 3.9 6.6e-11 42.4 2.7 3.6 2 1 1 3 3 3 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC76984.1 - 8.2e-08 32.3 1.9 8.2e-08 32.3 1.3 2.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.1 EMC76984.1 - 0.0044 17.0 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C14 PF00656.17 EMC76985.1 - 6.2e-49 166.9 0.1 7.3e-49 166.6 0.1 1.1 1 0 0 1 1 1 1 Caspase domain DUF607 PF04678.8 EMC76986.1 - 1.6e-58 197.5 2.5 2.1e-58 197.2 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF607 NDUF_C2 PF06374.6 EMC76986.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF2346 PF09803.4 EMC76986.1 - 0.12 12.2 0.3 0.12 12.2 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) Sec23_trunk PF04811.10 EMC76987.1 - 2.4e-86 289.0 0.1 4.6e-86 288.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC76987.1 - 2e-26 91.4 2.8 7.1e-26 89.6 2.0 2.1 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMC76987.1 - 2.7e-21 75.8 0.0 7.1e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMC76987.1 - 6.4e-16 57.6 5.1 1.3e-15 56.6 3.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMC76987.1 - 5.5e-09 35.5 0.0 1.5e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.5 EMC76987.1 - 0.071 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein Ribosomal_L34e PF01199.13 EMC76988.1 - 9.3e-38 128.3 8.1 1.2e-37 128.0 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e TatD_DNase PF01026.16 EMC76989.1 - 6.3e-09 35.4 0.0 3.8e-05 23.0 0.0 2.0 1 1 1 2 2 2 2 TatD related DNase CTNNB1_binding PF08347.6 EMC76990.1 - 1.5e-45 155.9 10.9 1.5e-45 155.9 7.6 2.3 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.14 EMC76990.1 - 8.5e-22 77.2 0.7 8.5e-22 77.2 0.5 2.5 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC76990.1 - 2.3e-08 34.3 0.5 6.4e-08 32.8 0.3 1.7 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EMC76990.1 - 0.029 13.6 0.1 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 3HCDH_N PF02737.13 EMC76991.1 - 6.3e-53 179.0 3.1 7.9e-53 178.7 2.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMC76991.1 - 1.2e-35 121.8 0.0 2.6e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain PAP2_C PF14360.1 EMC76992.1 - 4.4e-30 103.7 14.2 4.4e-30 103.7 9.9 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EMC76992.1 - 5.9e-05 22.7 14.1 0.00016 21.3 9.8 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EMC76992.1 - 0.00097 18.7 7.3 0.00097 18.7 5.0 1.9 2 1 0 2 2 2 1 PAP2 superfamily APS_kinase PF01583.15 EMC76993.1 - 1e-74 249.4 0.0 1.6e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 EMC76993.1 - 4.1e-69 232.1 0.1 6e-69 231.6 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EMC76993.1 - 5.3e-49 165.6 0.0 1.1e-48 164.6 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EMC76993.1 - 1.1e-09 38.3 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC76993.1 - 1.2e-06 29.3 0.1 6.3e-06 27.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC76993.1 - 0.00035 20.8 0.0 0.0012 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMC76993.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EMC76993.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 EMC76993.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase 6PF2K PF01591.13 EMC76993.1 - 0.027 13.5 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 EMC76993.1 - 0.06 13.3 0.2 0.57 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMC76993.1 - 0.087 12.0 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMC76993.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dickkopf_N PF04706.7 EMC76994.1 - 5.7e-20 71.2 19.3 5.7e-20 71.2 13.4 3.0 3 0 0 3 3 3 1 Dickkopf N-terminal cysteine-rich region Sperm_Ag_HE2 PF05324.8 EMC76994.1 - 0.069 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sperm antigen HE2 AIG1 PF04548.11 EMC76995.1 - 1.1e-26 93.2 0.0 1.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EMC76995.1 - 0.0025 17.7 0.0 0.004 17.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EMC76995.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 EMC76995.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T4_Gp59_C PF08994.5 EMC76995.1 - 0.074 13.2 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term RNase_P_Rpp14 PF01900.14 EMC76995.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Rpp14/Pop5 family tRNA_bind PF01588.15 EMC76996.1 - 1.8e-31 107.7 1.0 4e-31 106.7 0.1 2.0 2 0 0 2 2 2 1 Putative tRNA binding domain NUDE_C PF04880.8 EMC76996.1 - 4.4e-05 23.9 1.1 7.2e-05 23.1 0.8 1.4 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region DUF972 PF06156.8 EMC76996.1 - 0.021 15.1 2.5 0.021 15.1 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EMC76996.1 - 0.022 15.0 12.7 0.022 15.0 8.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CENP-U PF13097.1 EMC76996.1 - 0.57 10.1 10.4 3.6 7.4 0.8 2.3 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Ribosomal_60s PF00428.14 EMC76996.1 - 1.6 9.1 9.0 2.9 8.3 5.2 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein GAGA_bind PF06217.7 EMC76996.1 - 2.2 8.1 6.4 3.1 7.6 4.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RabGAP-TBC PF00566.13 EMC76997.1 - 9.1e-48 162.5 0.1 1.4e-47 161.9 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EMC76997.1 - 5.9e-32 110.8 0.0 8.7e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC76997.1 - 1.1e-23 83.6 0.0 1.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.15 EMC76997.1 - 4.8e-16 59.1 0.0 8.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.1 EMC76997.1 - 1.5e-05 24.0 0.0 2.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MAM PF00629.18 EMC76998.1 - 9.7e-26 90.4 0.0 2.1e-25 89.3 0.0 1.6 1 1 0 1 1 1 1 MAM domain EGF_CA PF07645.10 EMC76998.1 - 5.8e-23 80.6 36.4 1.5e-10 40.9 2.6 5.7 4 2 1 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 EMC76998.1 - 2.4e-18 65.4 41.5 3e-07 29.9 0.9 6.0 5 0 0 5 5 5 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EMC76998.1 - 9.2e-12 44.8 72.2 4.2e-06 26.7 4.6 5.6 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 EMC76998.1 - 1.2e-05 25.1 72.3 0.016 15.2 1.2 6.3 5 1 0 5 5 5 5 EGF-like domain EGF_3 PF12947.2 EMC76998.1 - 1.8e-05 24.5 19.9 0.00014 21.7 8.8 6.0 5 1 0 5 5 5 3 EGF domain C_tripleX PF02363.14 EMC76998.1 - 0.00081 19.2 4.7 0.0065 16.4 3.2 2.8 1 0 0 1 1 1 1 Cysteine rich repeat Methyltransf_32 PF13679.1 EMC76999.1 - 5.4e-13 48.8 0.3 1e-12 47.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC76999.1 - 7.5e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC76999.1 - 1.9e-06 28.3 0.0 8.5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TRM13 PF05206.9 EMC76999.1 - 4.1e-06 26.2 0.7 0.075 12.2 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase TRM13 GidB PF02527.10 EMC76999.1 - 6.9e-05 22.0 0.0 0.00015 20.9 0.0 1.5 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.9 EMC76999.1 - 0.00045 19.6 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GST_C_2 PF13410.1 EMC76999.1 - 0.0018 18.1 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_4 PF02390.12 EMC76999.1 - 0.0024 16.9 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EMC76999.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC76999.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DNA_pol_viral_C PF00336.13 EMC76999.1 - 0.043 13.0 0.1 0.074 12.2 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Methyltransf_16 PF10294.4 EMC76999.1 - 0.09 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PHD PF00628.24 EMC77000.1 - 1.2e-09 37.6 9.3 2e-09 37.0 6.5 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EMC77000.1 - 2.9e-05 23.7 3.3 2.9e-05 23.7 2.3 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMC77000.1 - 0.00018 21.1 3.4 0.00018 21.1 2.4 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EMC77000.1 - 0.00028 20.1 5.9 0.00059 19.0 4.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EMC77000.1 - 0.0011 18.3 3.3 0.0024 17.1 2.3 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain DUF4206 PF13901.1 EMC77000.1 - 0.004 16.7 4.7 0.0067 15.9 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) Cytochrom_c3_2 PF14537.1 EMC77000.1 - 0.13 12.6 8.6 0.18 12.1 4.3 2.4 1 1 1 2 2 2 0 Cytochrome c3 FYVE_2 PF02318.11 EMC77000.1 - 0.22 11.4 5.5 0.44 10.4 3.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrome_C7 PF14522.1 EMC77000.1 - 0.64 9.6 7.4 2 8.1 3.6 2.4 1 1 1 2 2 2 0 Cytochrome c7 zf-RING_2 PF13639.1 EMC77000.1 - 4 7.3 9.4 10 6.0 6.5 1.7 1 1 0 1 1 1 0 Ring finger domain BAR PF03114.13 EMC77001.1 - 2.5e-29 102.4 3.7 2.5e-29 102.4 2.6 1.7 2 0 0 2 2 2 1 BAR domain RhoGEF PF00621.15 EMC77001.1 - 5.6e-15 55.6 0.1 5.6e-15 55.6 0.1 2.6 3 0 0 3 3 3 1 RhoGEF domain SH3_2 PF07653.12 EMC77001.1 - 5e-13 48.3 0.0 1.4e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 EMC77001.1 - 2.7e-10 39.6 0.2 8.4e-10 38.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC77001.1 - 4.1e-09 35.6 0.4 2.2e-08 33.3 0.1 2.2 2 0 0 2 2 2 1 SH3 domain TINF2_N PF14973.1 EMC77001.1 - 2.8 8.0 7.8 0.6 10.2 0.2 2.7 2 1 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus RhoGEF PF00621.15 EMC77002.1 - 2.5e-21 76.3 0.7 3.3e-21 75.9 0.5 1.2 1 0 0 1 1 1 1 RhoGEF domain Pyrophosphatase PF00719.14 EMC77003.1 - 6.9e-54 181.5 0.5 8.2e-54 181.2 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Tet_JBP PF12851.2 EMC77004.1 - 1.9e-85 284.4 0.2 4.1e-85 283.3 0.1 1.6 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 7tm_1 PF00001.16 EMC77006.1 - 1.7e-63 214.1 20.0 2.3e-63 213.7 13.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77006.1 - 4.8e-11 42.3 19.5 6.3e-11 41.9 13.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PsbX PF06596.6 EMC77006.1 - 1.7 8.4 8.8 0.063 12.9 1.2 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Radial_spoke PF04712.7 EMC77007.1 - 4e-180 599.7 7.4 4e-180 599.7 5.1 1.9 1 1 1 2 2 2 1 Radial spokehead-like protein TBPIP PF07106.8 EMC77007.1 - 0.0086 15.6 0.0 0.0086 15.6 0.0 1.8 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Kinesin PF00225.18 EMC77008.1 - 8.5e-109 363.2 0.1 8.5e-109 363.2 0.0 4.0 2 1 0 3 3 3 1 Kinesin motor domain DUF904 PF06005.7 EMC77009.1 - 0.0034 17.6 8.1 0.0034 17.6 5.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF904) DUF1049 PF06305.6 EMC77009.1 - 0.18 11.2 5.1 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) V_ATPase_I PF01496.14 EMC77009.1 - 0.41 8.4 6.8 0.45 8.3 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EMC77009.1 - 0.53 9.1 4.7 0.65 8.9 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XRCC4 PF06632.7 EMC77009.1 - 0.76 8.5 7.6 1.1 7.9 2.1 2.5 2 1 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 HALZ PF02183.13 EMC77009.1 - 0.94 9.2 14.5 1.6 8.4 3.6 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper PGBA_C PF15437.1 EMC77009.1 - 2.2 8.4 12.8 4 7.6 1.4 2.4 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DivIC PF04977.10 EMC77009.1 - 2.9 7.4 13.1 0.61 9.6 1.7 2.6 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.8 EMC77009.1 - 5.6 7.0 9.9 4.3 7.3 1.2 2.3 2 0 0 2 2 2 0 DivIVA protein Fib_alpha PF08702.5 EMC77009.1 - 6.7 6.8 8.8 1.7 8.7 3.9 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 EMC77009.1 - 8.2 6.3 17.5 6.4 6.6 4.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Na_H_Exchanger PF00999.16 EMC77010.1 - 5.1e-27 94.3 35.2 5.1e-27 94.3 24.4 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family MitoNEET_N PF10660.4 EMC77011.1 - 1.3e-19 69.8 0.1 1.8e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.5 EMC77011.1 - 4e-10 39.3 0.5 6.7e-10 38.6 0.4 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type DUF1154 PF06631.6 EMC77011.1 - 2.1 8.0 0.0 2.1 8.0 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1154) UQ_con PF00179.21 EMC77012.1 - 5.6e-47 158.6 0.1 6.7e-47 158.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC77012.1 - 0.00021 21.0 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC77012.1 - 0.0021 17.9 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC77012.1 - 0.035 13.7 0.1 0.055 13.1 0.1 1.3 1 1 0 1 1 1 0 UEV domain Glyco_hydro_2_C PF02836.12 EMC77013.1 - 2e-08 33.5 0.2 3.9e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EMC77013.1 - 3.1e-08 33.3 0.1 9e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Zip PF02535.17 EMC77014.1 - 5.9e-67 225.9 4.3 7.8e-67 225.5 3.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF812 PF05667.6 EMC77015.1 - 0.016 13.7 1.9 0.019 13.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4554 PF15091.1 EMC77015.1 - 0.049 12.3 0.6 0.063 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DBB PF14545.1 EMC77016.1 - 4.8e-21 74.7 0.0 7.7e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Ank_2 PF12796.2 EMC77016.1 - 0.027 14.8 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMC77016.1 - 0.13 12.5 0.1 0.5 10.7 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.25 EMC77016.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 EMC77016.1 - 0.15 12.3 0.3 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Metallophos PF00149.23 EMC77017.1 - 5.4e-41 140.1 0.5 8.5e-41 139.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Endomucin PF07010.7 EMC77018.1 - 3.1e-22 79.1 0.0 3.6e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Endomucin DUF1628 PF07790.6 EMC77018.1 - 0.032 14.9 0.0 0.036 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) gpUL132 PF11359.3 EMC77018.1 - 0.033 13.5 0.1 0.046 13.0 0.0 1.3 1 1 0 1 1 1 0 Glycoprotein UL132 DUF4013 PF13197.1 EMC77018.1 - 0.041 13.2 0.1 0.046 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Sel1 PF08238.7 EMC77019.1 - 9.7e-09 35.5 3.3 1.1e-08 35.3 0.3 2.4 2 1 0 2 2 2 1 Sel1 repeat Fe_hyd_lg_C PF02906.9 EMC77019.1 - 0.018 14.3 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Histone PF00125.19 EMC77020.1 - 3.5e-22 78.3 0.1 4.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC77020.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1977 PF09320.6 EMC77021.1 - 1.1e-36 125.3 3.0 1.9e-36 124.5 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EMC77021.1 - 1e-26 92.4 0.6 2.2e-26 91.3 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3770 PF12603.3 EMC77021.1 - 0.046 12.8 2.1 0.075 12.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) Alpha_L_fucos PF01120.12 EMC77021.1 - 0.065 12.1 0.8 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Alpha-L-fucosidase DUF1955 PF09205.5 EMC77021.1 - 0.19 11.2 1.5 1.7 8.1 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) MAPKK1_Int PF08923.5 EMC77022.1 - 8.4e-46 154.4 0.0 9.3e-46 154.3 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting SH2 PF00017.19 EMC77023.1 - 8.9e-20 70.2 0.4 1.6e-19 69.4 0.3 1.5 1 0 0 1 1 1 1 SH2 domain PH PF00169.24 EMC77023.1 - 5.4e-16 58.6 0.6 1e-15 57.7 0.4 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC77023.1 - 1.4e-05 25.2 1.2 0.00013 22.1 0.5 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Vitellogenin_N PF01347.17 EMC77024.1 - 4.1e-61 206.9 9.5 5.1e-61 206.6 6.6 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region HEAT_2 PF13646.1 EMC77024.1 - 0.0012 19.1 1.8 0.079 13.2 0.1 2.8 1 1 1 2 2 2 1 HEAT repeats HTH_9 PF08221.6 EMC77024.1 - 2.1 8.3 5.1 13 5.7 0.1 3.9 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain tRNA_m1G_MT PF01746.16 EMC77025.1 - 1.6e-47 161.4 0.7 2.8e-47 160.7 0.5 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF4355 PF14265.1 EMC77025.1 - 0.0013 18.6 8.9 0.0027 17.6 6.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) NARP1 PF12569.3 EMC77025.1 - 0.082 11.6 8.6 0.12 11.1 6.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ADH_N PF08240.7 EMC77026.1 - 1.6e-27 95.4 1.3 3.7e-27 94.2 0.9 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC77026.1 - 4.6e-23 81.2 0.4 9.2e-23 80.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMC77026.1 - 0.027 13.8 0.2 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDEase_I PF00233.14 EMC77027.1 - 2.8e-94 315.3 4.9 5.9e-94 314.2 3.4 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 EMC77027.1 - 4.3e-39 134.1 0.0 6.8e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EMC77027.1 - 3.6e-13 49.7 0.0 9.6e-06 25.7 0.0 2.7 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.1 EMC77027.1 - 4e-09 37.1 0.0 0.00026 21.4 0.0 2.3 2 0 0 2 2 2 2 GAF domain DUF4316 PF14195.1 EMC77027.1 - 0.021 14.8 0.8 0.056 13.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) OB_NTP_bind PF07717.11 EMC77027.1 - 0.082 12.7 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Lipocalin PF00061.18 EMC77028.1 - 3.6e-18 65.9 0.0 4.6e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.7 EMC77028.1 - 1.5e-09 37.7 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.8 EMC77028.1 - 1.1e-05 25.1 0.1 0.00084 19.0 0.0 2.2 2 0 0 2 2 2 2 Triabin Glyco_hydro_39 PF01229.12 EMC77029.1 - 3.2e-154 513.9 0.0 3.9e-154 513.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Sulfate_transp PF00916.15 EMC77030.1 - 7.5e-72 241.6 13.3 7.5e-72 241.6 9.2 1.9 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMC77030.1 - 2.3e-29 100.8 3.1 2.3e-29 100.8 2.1 3.7 4 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMC77030.1 - 1.6e-25 88.8 0.1 4.4e-25 87.3 0.0 1.8 2 0 0 2 2 2 1 STAS domain Neur_chan_memb PF02932.11 EMC77031.1 - 4.4e-84 282.0 6.6 6e-84 281.6 4.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC77031.1 - 1.8e-74 249.5 4.1 3.4e-74 248.6 2.9 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4451 PF14616.1 EMC77031.1 - 0.016 15.0 3.1 0.032 13.9 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Neur_chan_LBD PF02931.18 EMC77032.1 - 1.1e-73 246.9 0.3 1.8e-73 246.2 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC77032.1 - 6.3e-59 199.7 13.5 2e-56 191.5 9.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region YgaB PF14182.1 EMC77032.1 - 0.1 12.8 0.4 0.2 11.9 0.3 1.4 1 0 0 1 1 1 0 YgaB-like protein PepSY_TM_3 PF13706.1 EMC77032.1 - 5.9 6.4 11.4 0.15 11.5 1.7 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix THAP PF05485.7 EMC77033.1 - 4.4e-21 74.8 8.9 1.2e-20 73.5 6.2 1.7 1 0 0 1 1 1 1 THAP domain Cep57_CLD PF14073.1 EMC77033.1 - 5.2e-05 23.1 3.1 7.7e-05 22.5 2.2 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 RTBV_P46 PF06216.6 EMC77033.1 - 0.0038 16.1 0.4 0.0049 15.7 0.3 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein DUF4391 PF14335.1 EMC77033.1 - 0.0043 16.4 2.6 0.0065 15.8 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) ADIP PF11559.3 EMC77033.1 - 0.0048 16.8 9.6 0.0073 16.2 6.7 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding 7TMR-HDED PF07697.6 EMC77033.1 - 0.0056 16.4 1.2 0.008 15.9 0.9 1.1 1 0 0 1 1 1 1 7TM-HD extracellular DivIC PF04977.10 EMC77033.1 - 0.0066 15.9 3.0 0.011 15.1 2.1 1.3 1 0 0 1 1 1 1 Septum formation initiator Mitofilin PF09731.4 EMC77033.1 - 0.0076 14.9 0.2 0.01 14.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Macoilin PF09726.4 EMC77033.1 - 0.0082 14.4 4.3 0.011 14.0 3.0 1.1 1 0 0 1 1 1 1 Transmembrane protein L31 PF09784.4 EMC77033.1 - 0.013 15.5 1.9 0.029 14.4 1.3 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Tropomyosin_1 PF12718.2 EMC77033.1 - 0.014 15.2 4.8 0.023 14.5 3.3 1.3 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.15 EMC77033.1 - 0.015 14.3 6.8 0.022 13.8 4.7 1.1 1 0 0 1 1 1 0 Tropomyosin GrpE PF01025.14 EMC77033.1 - 0.02 14.4 3.6 0.031 13.8 2.5 1.2 1 0 0 1 1 1 0 GrpE FemAB PF02388.11 EMC77033.1 - 0.025 13.2 1.1 0.034 12.8 0.7 1.1 1 0 0 1 1 1 0 FemAB family AAA_27 PF13514.1 EMC77033.1 - 0.029 12.0 2.1 0.036 11.7 1.4 1.0 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EMC77033.1 - 0.032 14.6 0.8 0.048 14.1 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3373 PF11853.3 EMC77033.1 - 0.067 11.7 1.4 0.087 11.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF607 PF04678.8 EMC77033.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 YPEB PF14620.1 EMC77033.1 - 0.07 12.1 2.2 0.097 11.6 1.6 1.1 1 0 0 1 1 1 0 YpeB sporulation IncA PF04156.9 EMC77033.1 - 0.13 11.8 5.5 0.18 11.3 3.8 1.1 1 0 0 1 1 1 0 IncA protein Vac_Fusion PF02346.11 EMC77033.1 - 0.17 11.3 3.7 0.32 10.4 2.5 1.4 1 0 0 1 1 1 0 Chordopoxvirus fusion protein FliD_C PF07195.7 EMC77033.1 - 0.18 11.1 1.4 0.24 10.6 0.9 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.4 EMC77033.1 - 0.27 10.1 10.6 0.39 9.6 7.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EAP30 PF04157.11 EMC77033.1 - 0.29 10.2 3.3 0.38 9.8 2.3 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF2951 PF11166.3 EMC77033.1 - 0.3 10.9 6.3 0.53 10.1 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) APG6 PF04111.7 EMC77033.1 - 0.36 9.8 4.1 0.49 9.3 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EMC77033.1 - 0.5 10.3 2.9 0.81 9.6 2.0 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ABC_tran_2 PF12848.2 EMC77033.1 - 0.56 10.0 9.5 1 9.2 6.6 1.4 1 0 0 1 1 1 0 ABC transporter DUF3391 PF11871.3 EMC77033.1 - 0.64 10.2 5.9 86 3.3 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) 4HBT_3 PF13622.1 EMC77033.1 - 1.4 8.6 6.7 1.9 8.1 4.6 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily XhlA PF10779.4 EMC77033.1 - 1.8 8.4 4.4 2.8 7.9 3.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF1232 PF06803.7 EMC77034.1 - 6.1e-10 38.3 8.6 6.1e-10 38.3 5.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-C3HC4_3 PF13920.1 EMC77034.1 - 4.5e-09 35.8 2.5 6.6e-09 35.3 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC77034.1 - 1.4e-08 34.6 7.1 2.2e-08 33.9 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77034.1 - 1.8e-08 33.9 4.1 3.1e-08 33.1 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77034.1 - 3.5e-08 33.1 6.7 5.9e-08 32.4 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EMC77034.1 - 4.6e-08 32.7 4.9 1.1e-07 31.5 3.5 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMC77034.1 - 2.6e-06 27.0 4.4 5.3e-06 26.0 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC77034.1 - 2.7e-05 23.7 1.3 2.7e-05 23.7 0.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EMC77034.1 - 0.022 14.3 1.1 0.04 13.4 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cys_rich_CPXG PF14255.1 EMC77034.1 - 0.027 14.2 0.7 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-Apc11 PF12861.2 EMC77034.1 - 0.037 13.8 2.0 0.07 12.9 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMC77034.1 - 0.12 12.5 1.9 0.23 11.5 1.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 EMC77034.1 - 0.15 11.9 3.0 0.31 10.9 2.1 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain DRP PF06044.7 EMC77034.1 - 0.8 8.6 3.0 5.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Dam-replacing family zf-MIZ PF02891.15 EMC77034.1 - 1.8 8.1 8.3 3.8 7.0 5.8 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Baculo_IE-1 PF05290.6 EMC77034.1 - 2.6 7.7 4.9 7.8 6.2 3.5 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) HOOK PF05622.7 EMC77035.1 - 5e-214 712.2 41.8 5.5e-214 712.0 29.0 1.0 1 0 0 1 1 1 1 HOOK protein bZIP_1 PF00170.16 EMC77035.1 - 1.2e-05 25.2 47.3 0.03 14.2 6.0 6.4 2 2 3 6 6 6 4 bZIP transcription factor HALZ PF02183.13 EMC77035.1 - 0.00012 21.7 2.7 0.00012 21.7 1.9 6.6 5 1 2 7 7 6 2 Homeobox associated leucine zipper Filament PF00038.16 EMC77035.1 - 0.0016 17.9 35.3 0.0016 17.9 24.4 3.1 3 1 0 3 3 3 1 Intermediate filament protein PspA_IM30 PF04012.7 EMC77035.1 - 0.0016 17.8 38.1 0.068 12.5 12.6 2.8 1 1 2 3 3 3 2 PspA/IM30 family Myosin_tail_1 PF01576.14 EMC77035.1 - 0.0022 15.8 54.3 0.038 11.7 27.2 2.0 1 1 0 2 2 2 2 Myosin tail DUF972 PF06156.8 EMC77035.1 - 0.0058 16.9 46.5 0.084 13.2 3.1 5.4 2 1 4 6 6 5 3 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 EMC77035.1 - 0.006 16.6 8.7 0.006 16.6 6.0 5.0 3 1 2 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 EMC77035.1 - 0.0092 15.8 49.7 1.6 8.5 4.5 3.9 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) GAS PF13851.1 EMC77035.1 - 0.022 13.9 53.5 0.16 11.1 12.8 4.1 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EMC77035.1 - 0.044 13.5 55.5 0.38 10.5 15.7 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EMC77035.1 - 0.14 10.6 34.8 0.026 12.9 17.1 2.1 2 0 0 2 2 2 0 AAA domain DUF4005 PF13178.1 EMC77035.1 - 0.15 12.3 0.4 0.29 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) Seryl_tRNA_N PF02403.17 EMC77035.1 - 0.18 11.8 39.0 1 9.4 6.1 4.1 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 EMC77035.1 - 0.18 11.5 29.5 0.18 11.5 3.2 3.9 1 1 2 4 4 4 0 Laminin Domain II AAA_27 PF13514.1 EMC77035.1 - 0.22 9.1 42.5 0.32 8.6 20.9 2.1 1 1 1 2 2 2 0 AAA domain DUF869 PF05911.6 EMC77035.1 - 0.25 9.5 42.8 0.7 8.0 13.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) IncA PF04156.9 EMC77035.1 - 0.29 10.7 60.8 0.42 10.1 17.3 4.0 1 1 1 3 3 3 0 IncA protein Syntaxin PF00804.20 EMC77035.1 - 0.39 10.9 34.2 0.67 10.1 1.3 3.7 1 1 3 4 4 4 0 Syntaxin Reo_sigmaC PF04582.7 EMC77035.1 - 0.68 9.0 15.7 2.5 7.2 3.4 3.0 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Taxilin PF09728.4 EMC77035.1 - 0.78 8.7 50.5 0.33 9.9 9.5 4.1 1 1 3 4 4 4 0 Myosin-like coiled-coil protein CCDC155 PF14662.1 EMC77035.1 - 0.82 9.2 57.6 1.8 8.1 17.7 4.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 ERM PF00769.14 EMC77035.1 - 0.83 9.1 55.5 10 5.5 4.0 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family NPV_P10 PF05531.7 EMC77035.1 - 1.9 8.7 25.5 1.7 8.9 0.0 6.6 3 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Rootletin PF15035.1 EMC77035.1 - 2.3 8.1 57.0 0.12 12.3 15.3 3.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 EMC77035.1 - 2.6 7.8 60.1 0.43 10.4 15.4 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 EMC77035.1 - 3.4 6.8 38.1 0.67 9.1 5.6 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 EMC77035.1 - 5.8 5.4 51.4 1.3 7.6 11.7 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Mod_r PF07200.8 EMC77035.1 - 6.9 6.5 45.3 0.98 9.3 12.2 3.9 1 1 2 3 3 2 0 Modifier of rudimentary (Mod(r)) protein WD40_alt PF14077.1 EMC77035.1 - 8 6.1 9.8 3.4 7.3 0.5 4.5 4 0 0 4 4 4 0 Alternative WD40 repeat motif DUF2353 PF09789.4 EMC77035.1 - 9.1 5.4 42.2 1.3 8.1 21.5 2.3 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) APG6 PF04111.7 EMC77035.1 - 9.4 5.1 55.8 7.7 5.4 6.0 3.1 1 1 1 3 3 3 0 Autophagy protein Apg6 Uds1 PF15456.1 EMC77035.1 - 10 6.1 40.2 0.11 12.5 11.0 3.9 1 1 2 3 3 3 0 Up-regulated During Septation Collagen PF01391.13 EMC77036.1 - 4.9e-21 74.0 75.3 2.6e-08 33.2 7.6 5.2 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 EMC77037.1 - 3.4e-38 131.2 51.5 2.4e-37 128.4 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EMC77037.1 - 2.5e-12 45.6 17.3 1.2e-05 23.6 0.1 4.0 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EMC77037.1 - 2.8e-12 45.9 25.7 3.9e-12 45.4 17.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EMC77037.1 - 6.1e-06 24.8 25.4 5e-05 21.8 4.8 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 EMC77037.1 - 0.0005 18.6 6.9 0.0005 18.6 4.8 2.7 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like UQ_con PF00179.21 EMC77038.1 - 6.3e-50 168.2 0.0 7.1e-50 168.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC77038.1 - 0.076 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ank_2 PF12796.2 EMC77039.1 - 2.6e-107 351.3 27.3 8.2e-20 70.9 0.0 11.4 4 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EMC77039.1 - 5.4e-101 325.7 41.9 5.7e-12 44.8 0.0 22.1 22 1 0 22 22 22 18 Ankyrin repeat Ank_4 PF13637.1 EMC77039.1 - 7.4e-72 236.5 29.6 1.1e-07 32.2 0.0 18.2 6 5 13 19 19 19 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC77039.1 - 1.4e-71 234.8 33.3 3.4e-09 36.6 0.0 15.2 11 3 5 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77039.1 - 7.9e-69 220.6 30.6 6e-05 22.8 0.0 20.9 22 0 0 22 22 22 14 Ankyrin repeat FYVE PF01363.16 EMC77039.1 - 1.7e-16 59.8 9.8 4.2e-16 58.5 6.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger BTB PF00651.26 EMC77039.1 - 1.2e-15 57.4 0.1 4.6e-15 55.5 0.1 2.1 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EMC77039.1 - 0.015 15.1 0.4 0.015 15.1 0.3 2.4 3 1 0 3 3 3 0 BTB And C-terminal Kelch FYVE_2 PF02318.11 EMC77039.1 - 0.64 9.9 11.4 0.31 10.9 5.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger ZZ PF00569.12 EMC77040.1 - 2.2e-16 59.1 19.3 2.1e-08 33.5 3.1 2.9 2 0 0 2 2 2 2 Zinc finger, ZZ type APC10 PF03256.11 EMC77040.1 - 2e-11 43.8 0.4 5e-11 42.5 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EMC77040.1 - 0.0012 18.7 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain EF-hand_1 PF00036.27 EMC77040.1 - 0.0034 16.5 0.1 0.01 15.0 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMC77040.1 - 0.014 15.2 0.0 0.067 13.1 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EMC77040.1 - 0.023 14.7 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EMC77040.1 - 0.12 11.7 0.1 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 EF hand E1-E2_ATPase PF00122.15 EMC77042.1 - 3.3e-68 229.1 4.2 7.5e-68 227.9 0.9 2.5 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC77042.1 - 3.2e-44 150.6 3.6 3.2e-44 150.6 2.5 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC77042.1 - 4.7e-30 105.6 0.0 2.5e-28 99.9 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC77042.1 - 7.7e-23 80.2 1.1 1.5e-22 79.3 0.8 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMC77042.1 - 3.6e-15 56.6 0.2 1.5e-14 54.6 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC77042.1 - 8.1e-07 28.8 1.4 1.3e-06 28.1 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMC77042.1 - 6.3e-06 25.5 0.1 6.3e-06 25.5 0.1 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Pkinase PF00069.20 EMC77043.1 - 8.6e-66 221.7 0.0 1.4e-65 221.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77043.1 - 2.1e-33 115.5 0.0 2.9e-31 108.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC77043.1 - 5.4e-09 35.4 0.0 8.6e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC77043.1 - 0.21 11.2 0.2 0.58 9.8 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mis12 PF05859.7 EMC77044.1 - 2.2e-40 137.7 4.2 2.2e-40 137.7 2.9 1.5 2 0 0 2 2 2 1 Mis12 protein DUF2018 PF09442.5 EMC77044.1 - 0.0015 19.0 1.3 0.0026 18.3 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2018) Lzipper-MIP1 PF14389.1 EMC77044.1 - 0.016 15.2 2.1 0.016 15.2 1.4 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 IncA PF04156.9 EMC77044.1 - 0.018 14.6 7.4 0.025 14.2 5.1 1.4 1 0 0 1 1 1 0 IncA protein Z1 PF10593.4 EMC77044.1 - 0.032 13.4 4.1 2.2 7.4 0.0 3.0 2 1 1 3 3 3 0 Z1 domain DUF1098 PF06497.6 EMC77044.1 - 0.063 13.3 0.2 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) BBP1_C PF15272.1 EMC77044.1 - 0.15 11.5 0.4 0.15 11.5 0.3 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal LLC1 PF14945.1 EMC77044.1 - 0.22 11.8 1.4 2 8.7 0.1 2.2 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Spectrin PF00435.16 EMC77044.1 - 0.26 11.5 7.8 0.094 13.0 2.1 2.1 2 0 0 2 2 2 0 Spectrin repeat Metal_resist PF13801.1 EMC77044.1 - 0.48 10.4 7.3 0.67 9.9 4.2 1.8 2 0 0 2 2 2 0 Heavy-metal resistance V_ATPase_I PF01496.14 EMC77044.1 - 0.61 7.8 4.9 0.98 7.1 3.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.1 EMC77044.1 - 0.67 9.9 9.9 0.44 10.5 3.1 2.2 2 0 0 2 2 2 0 FlxA-like protein BLOC1_2 PF10046.4 EMC77044.1 - 0.88 9.7 5.8 1 9.5 0.5 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.1 EMC77044.1 - 1.9 9.0 5.9 1.1 9.7 1.7 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EMC77044.1 - 10 5.7 10.3 7.8 6.0 3.3 2.4 2 0 0 2 2 2 0 Septum formation initiator DER1 PF04511.10 EMC77045.1 - 3.5e-62 209.4 12.3 3.9e-62 209.2 8.6 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 EMC77045.1 - 0.3 11.0 19.0 0.48 10.4 13.2 1.3 1 1 0 1 1 1 0 Rhomboid family DUF2304 PF10066.4 EMC77045.1 - 3.9 7.3 6.5 0.75 9.6 1.2 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) OB_NTP_bind PF07717.11 EMC77046.1 - 9.5e-24 83.4 0.0 2e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC77046.1 - 1.5e-22 79.5 0.0 2.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC77046.1 - 1.3e-13 50.6 0.0 3.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC77046.1 - 2.9e-06 26.8 0.5 9.2e-06 25.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC77046.1 - 0.041 14.0 0.1 0.14 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain MAM33 PF02330.11 EMC77047.1 - 3.4e-69 232.6 4.9 3.8e-69 232.5 3.4 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF524 PF04411.7 EMC77047.1 - 0.0024 17.7 0.1 0.0064 16.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF524) Rabaptin PF03528.10 EMC77049.1 - 2.6e-78 258.8 32.8 4e-43 145.6 11.5 9.6 5 3 1 6 6 6 3 Rabaptin Rab5-bind PF09311.6 EMC77049.1 - 1.6e-44 151.9 38.7 1.6e-44 151.9 26.9 5.7 3 1 3 6 6 6 2 Rabaptin-like protein Ras PF00071.17 EMC77050.1 - 5.6e-07 29.0 0.0 7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EMC77050.1 - 0.0019 17.4 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMC77050.1 - 0.0073 16.8 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein EMI PF07546.8 EMC77051.1 - 1.7e-25 89.2 10.3 3e-25 88.4 7.2 1.4 1 0 0 1 1 1 1 EMI domain Collagen PF01391.13 EMC77051.1 - 2.4e-20 71.8 77.0 2.4e-09 36.6 22.2 3.5 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) DUF2360 PF10152.4 EMC77051.1 - 0.16 12.2 0.0 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PspB PF06667.7 EMC77051.1 - 0.22 11.4 0.6 12 5.9 0.0 2.7 3 0 0 3 3 3 0 Phage shock protein B 3Beta_HSD PF01073.14 EMC77052.1 - 4.6e-49 166.6 0.0 5.6e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC77052.1 - 3.7e-09 36.3 0.0 5.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC77052.1 - 3.5e-07 29.3 0.0 4.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMC77052.1 - 0.097 11.5 0.2 3 6.6 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein EF-hand_1 PF00036.27 EMC77053.1 - 2.2e-14 51.5 3.9 5.1e-06 25.4 0.6 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EMC77053.1 - 6.6e-11 42.1 0.4 4.5e-06 26.6 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC77053.1 - 2.7e-10 39.2 3.2 2.8e-06 26.7 0.5 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC77053.1 - 2.9e-09 36.3 1.5 0.0092 15.5 0.1 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EMC77053.1 - 4.3e-05 22.6 2.9 0.00032 19.9 1.1 2.7 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.5 EMC77053.1 - 0.0006 19.7 0.5 0.074 13.0 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.1 EMC77053.1 - 0.11 12.4 0.0 0.96 9.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain DUF1168 PF06658.7 EMC77054.1 - 1.6e-47 160.6 22.1 2.1e-47 160.2 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF911 PF06023.7 EMC77054.1 - 0.2 10.8 1.5 0.25 10.5 1.0 1.1 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) BPL_N PF09825.4 EMC77054.1 - 0.28 9.8 5.3 0.35 9.5 3.6 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal rRNA_processing PF08524.6 EMC77054.1 - 0.35 10.6 27.4 0.53 10.0 19.0 1.2 1 0 0 1 1 1 0 rRNA processing FLO_LFY PF01698.11 EMC77054.1 - 0.63 8.8 15.9 0.79 8.5 11.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RP-C_C PF11800.3 EMC77054.1 - 0.87 9.2 11.9 1.6 8.3 8.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2413 PF10310.4 EMC77054.1 - 1.2 7.9 18.3 1.4 7.6 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Peptidase_C58 PF03543.9 EMC77054.1 - 2.2 7.7 10.9 2.9 7.3 7.5 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen GAGA_bind PF06217.7 EMC77054.1 - 2.2 8.1 13.3 2.7 7.8 9.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EMC77054.1 - 3.4 7.4 12.6 4.5 7.0 8.7 1.2 1 0 0 1 1 1 0 DDHD domain BTV_NS2 PF04514.7 EMC77054.1 - 7.5 5.3 20.3 10 4.8 14.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 EMC77054.1 - 9.8 3.7 13.3 11 3.6 9.2 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 EMC77054.1 - 10 6.1 23.2 18 5.3 16.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Orai-1 PF07856.7 EMC77055.1 - 1.5e-78 262.3 6.5 1.8e-78 262.1 4.5 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity GP4 PF03010.9 EMC77055.1 - 0.051 13.1 0.9 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 GP4 zf-LITAF-like PF10601.4 EMC77055.1 - 0.082 12.7 7.1 0.46 10.3 0.0 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF2207 PF09972.4 EMC77055.1 - 0.09 11.3 1.4 0.13 10.7 1.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-DHHC PF01529.15 EMC77055.1 - 2.1 7.6 4.7 9.3 5.6 3.3 1.9 1 1 0 1 1 1 0 DHHC palmitoyltransferase 2OG-FeII_Oxy_2 PF13532.1 EMC77056.1 - 2.8e-05 24.0 0.0 4.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMC77056.1 - 0.00025 21.2 0.0 0.0036 17.5 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol_L_2 PF13656.1 EMC77057.1 - 1.1e-29 101.6 0.1 1.3e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMC77057.1 - 2.9e-12 45.5 0.0 3.5e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RasGAP PF00616.14 EMC77058.1 - 6.3e-43 146.7 0.0 7.9e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EMC77059.1 - 5e-15 55.1 0.0 9.9e-15 54.1 0.0 1.5 2 0 0 2 2 2 1 C2 domain WWE PF02825.15 EMC77060.1 - 3.7e-32 109.5 0.2 7.5e-16 57.3 0.0 2.4 2 0 0 2 2 2 2 WWE domain zf-rbx1 PF12678.2 EMC77060.1 - 4.4e-05 23.5 2.2 4.4e-05 23.5 1.5 2.2 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMC77060.1 - 5e-05 23.0 9.1 0.00027 20.7 6.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC77060.1 - 0.00035 20.1 7.8 0.00094 18.7 5.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC77060.1 - 0.013 15.3 1.6 0.047 13.5 1.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMC77060.1 - 0.65 9.7 9.6 0.21 11.3 4.3 2.1 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC77060.1 - 3.2 7.8 12.0 9.8 6.2 4.5 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMC77060.1 - 8.1 6.2 9.6 2.6 7.8 4.0 2.3 2 1 0 2 2 2 0 PHD-finger 14-3-3 PF00244.15 EMC77061.1 - 6e-100 333.1 8.2 6.7e-100 333.0 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1987 PF09345.5 EMC77061.1 - 0.35 10.6 2.1 1.6 8.6 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1987) DUF3107 PF11305.3 EMC77062.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) Ldh_1_C PF02866.13 EMC77063.1 - 2.2e-51 174.0 0.0 3.3e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EMC77063.1 - 1e-47 161.5 0.0 1.5e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EMC77063.1 - 0.0013 19.0 0.0 0.0093 16.2 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMC77063.1 - 0.0024 16.6 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC77063.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EMC77063.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.14 EMC77063.1 - 0.072 12.1 0.2 0.45 9.5 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DSPc PF00782.15 EMC77064.1 - 5.6e-21 74.5 0.1 8.3e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EMC77064.1 - 2.5e-05 24.5 0.3 9.9e-05 22.6 0.2 1.9 1 1 0 1 1 1 1 Rhodanese-like domain TMPIT PF07851.8 EMC77065.1 - 5e-160 532.0 18.1 6.2e-160 531.6 12.6 1.0 1 0 0 1 1 1 1 TMPIT-like protein ALIX_LYPXL_bnd PF13949.1 EMC77065.1 - 0.0069 15.3 5.3 0.01 14.8 3.7 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV IFT57 PF10498.4 EMC77065.1 - 0.1 11.3 5.0 0.14 10.8 3.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FAD_binding_1 PF00667.15 EMC77066.1 - 7.2e-82 274.0 0.0 1.1e-81 273.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMC77066.1 - 7.4e-39 133.0 0.4 2.5e-38 131.3 0.2 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EMC77066.1 - 9e-24 84.1 0.2 1.5e-22 80.2 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain DUF3755 PF12579.3 EMC77066.1 - 0.063 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Transketolase_C PF02780.15 EMC77066.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain RRM_1 PF00076.17 EMC77067.1 - 3.2e-13 49.1 0.1 1.7e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EMC77067.1 - 2.2e-08 33.0 5.9 3.3e-08 32.4 4.1 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_6 PF14259.1 EMC77067.1 - 2.8e-08 33.6 0.0 4.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC77067.1 - 0.00077 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M10 PF00413.19 EMC77068.1 - 1.9e-48 164.1 0.0 3.2e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC77068.1 - 3.1e-30 103.6 8.3 3.8e-08 32.9 0.0 4.7 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 EMC77068.1 - 2.1e-07 30.8 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_4 PF13583.1 EMC77068.1 - 0.0017 17.8 0.2 0.0025 17.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC77068.1 - 0.0028 17.5 0.1 0.0047 16.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC77068.1 - 0.0039 17.6 0.5 0.0063 17.0 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC77068.1 - 0.0047 17.0 0.1 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EMC77068.1 - 0.01 15.1 0.6 0.017 14.4 0.1 1.5 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.6 EMC77068.1 - 0.056 13.1 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.4 EMC77068.1 - 0.078 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.3 EMC77068.1 - 0.17 10.3 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Astacin PF01400.19 EMC77068.1 - 0.18 11.1 0.3 0.54 9.6 0.1 1.9 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) GAS2 PF02187.12 EMC77069.1 - 2.1e-36 123.5 0.2 3.5e-36 122.8 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 EMC77069.1 - 3.6e-10 39.8 0.0 7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Ras PF00071.17 EMC77070.1 - 4.3e-25 87.9 0.0 8.4e-25 87.0 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC77070.1 - 1e-14 55.0 0.0 2.3e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC77070.1 - 0.00054 19.2 0.0 0.0087 15.3 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC77070.1 - 0.0051 16.7 0.0 0.0072 16.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EMC77070.1 - 0.0054 16.6 0.0 0.0096 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC77070.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMC77070.1 - 0.093 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 EMC77070.1 - 0.13 12.0 0.1 0.27 11.0 0.0 1.9 1 1 0 1 1 1 0 Dynamin family Adaptin_N PF01602.15 EMC77071.1 - 1.8e-155 518.2 13.8 2.2e-155 517.9 9.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 EMC77071.1 - 9.6e-38 128.5 0.2 2.5e-37 127.2 0.1 1.9 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Cnd1 PF12717.2 EMC77071.1 - 2.9e-36 124.9 6.4 1.9e-35 122.3 0.4 3.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMC77071.1 - 7.6e-22 77.4 4.8 1.6e-10 41.1 0.0 5.8 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.17 EMC77071.1 - 6.2e-13 47.6 7.7 0.0038 17.1 0.0 7.0 7 0 0 7 7 7 4 HEAT repeat Alpha_adaptinC2 PF02883.15 EMC77071.1 - 3.5e-11 43.4 0.2 8.5e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.18 EMC77071.1 - 8.1e-08 31.8 3.3 0.0045 16.7 0.0 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EMC77071.1 - 0.00035 20.9 7.8 1.3 9.6 0.0 6.1 5 3 1 6 6 6 2 HEAT-like repeat Cnd3 PF12719.2 EMC77071.1 - 0.0019 17.2 2.6 0.019 13.9 0.0 2.7 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 EMC77071.1 - 0.0048 16.2 2.4 0.94 8.7 0.2 4.0 2 1 1 3 3 3 1 CLASP N terminal MOR2-PAG1_C PF14225.1 EMC77071.1 - 0.054 13.2 0.8 0.81 9.3 0.0 2.4 2 1 0 2 2 2 0 Cell morphogenesis C-terminal Pex2_Pex12 PF04757.9 EMC77072.1 - 5.1e-48 163.4 3.7 6.5e-48 163.1 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EMC77072.1 - 1.6e-06 27.9 2.5 2.7e-06 27.2 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC77072.1 - 0.00084 18.9 2.2 0.0015 18.1 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77072.1 - 0.0055 16.3 1.2 0.0095 15.5 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77072.1 - 0.013 15.2 5.6 0.15 11.8 4.1 2.1 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EMC77072.1 - 0.031 14.0 0.8 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 EMC77072.1 - 0.88 9.7 3.1 6.8 6.8 2.1 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger DUF4187 PF13821.1 EMC77072.1 - 1.2 8.8 3.1 23 4.6 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) AAA_4 PF04326.9 EMC77073.1 - 1.5e-18 67.1 0.1 2.4e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 Divergent AAA domain DUF2075 PF09848.4 EMC77073.1 - 1.3e-07 30.9 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EMC77073.1 - 0.0003 20.0 0.7 0.17 11.1 0.0 2.5 1 1 1 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 EMC77073.1 - 0.00087 19.4 0.1 0.029 14.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC77073.1 - 0.0011 18.8 0.1 0.0034 17.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMC77073.1 - 0.0035 16.2 0.0 0.023 13.5 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain Bac_DnaA PF00308.13 EMC77073.1 - 0.0036 16.9 0.1 0.0096 15.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein PIF1 PF05970.9 EMC77073.1 - 0.0042 16.0 0.1 0.01 14.8 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_25 PF13481.1 EMC77073.1 - 0.0071 15.7 0.0 0.049 13.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EMC77073.1 - 0.0078 16.4 0.1 0.043 14.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EMC77073.1 - 0.017 14.9 0.1 0.047 13.5 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EMC77073.1 - 0.022 14.4 0.0 0.074 12.8 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain AAA_11 PF13086.1 EMC77073.1 - 0.032 13.7 0.5 0.12 11.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EMC77073.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EMC77073.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EMC77073.1 - 0.081 12.0 0.0 0.46 9.5 0.0 2.1 2 0 0 2 2 2 0 KaiC DEAD PF00270.24 EMC77073.1 - 0.1 12.0 0.2 8.8 5.7 0.0 2.7 2 1 1 3 3 3 0 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 EMC77074.1 - 1.4e-12 47.0 11.8 1.4e-12 47.0 8.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.4 EMC77074.1 - 5.2e-07 29.4 0.7 0.032 13.8 0.1 2.4 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding zf-C3HC4_2 PF13923.1 EMC77074.1 - 4.4e-05 23.4 14.8 4.4e-05 23.4 10.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EMC77074.1 - 4.7e-05 23.2 4.7 4.7e-05 23.2 3.2 2.6 2 1 0 2 2 1 1 FYVE-type zinc finger SAP PF02037.22 EMC77074.1 - 0.00056 19.3 1.2 0.5 9.9 0.1 3.3 4 0 0 4 4 4 2 SAP domain zf-RING_5 PF14634.1 EMC77074.1 - 0.0019 17.8 12.1 0.0019 17.8 8.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EMC77074.1 - 0.0059 16.1 6.7 0.0059 16.1 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.16 EMC77074.1 - 0.0063 16.3 10.6 0.0063 16.3 7.3 3.6 2 2 0 2 2 1 1 FYVE zinc finger IBR PF01485.16 EMC77074.1 - 0.62 9.9 17.8 0.29 11.0 3.4 2.7 2 0 0 2 2 2 0 IBR domain zf-C3HC4_4 PF15227.1 EMC77074.1 - 3.2 7.7 26.5 0.95 9.3 3.9 3.8 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Siva PF05458.7 EMC77074.1 - 3.7 7.1 15.0 0.028 14.0 2.3 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) IL8 PF00048.15 EMC77076.1 - 4.6e-16 58.5 4.7 4.6e-16 58.5 3.2 1.5 1 1 1 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like LSR PF05624.9 EMC77076.1 - 2.1 8.1 11.2 8.8 6.1 0.1 2.7 2 1 0 2 2 2 0 Lipolysis stimulated receptor (LSR) IL8 PF00048.15 EMC77077.1 - 5.2e-14 51.9 1.5 6.4e-14 51.6 1.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF3963 PF13124.1 EMC77077.1 - 0.43 10.4 1.9 0.87 9.4 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) IL8 PF00048.15 EMC77078.1 - 5.2e-22 77.5 0.3 6.6e-22 77.2 0.2 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like zf-HC5HC2H PF13771.1 EMC77079.1 - 7.2e-15 54.9 4.7 7.2e-15 54.9 3.3 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC77079.1 - 0.00089 19.2 9.8 0.00089 19.2 6.8 3.3 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC77080.1 - 8.7e-15 54.6 4.5 8.7e-15 54.6 3.1 3.9 4 1 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC77080.1 - 0.0041 17.1 11.3 0.0041 17.1 7.9 3.6 1 1 1 3 3 3 1 PHD-zinc-finger like domain IL8 PF00048.15 EMC77081.1 - 6.3e-08 32.4 0.2 8.6e-08 32.0 0.2 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like FERM_C PF09380.5 EMC77082.1 - 1.7e-34 117.9 0.6 1.7e-34 117.9 0.4 2.4 3 0 0 3 3 3 1 FERM C-terminal PH-like domain ERM PF00769.14 EMC77082.1 - 1e-32 113.6 41.9 1e-32 113.6 29.0 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.13 EMC77082.1 - 3e-24 85.5 1.7 3e-24 85.5 1.2 2.8 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 EMC77082.1 - 3.5e-13 49.3 0.1 3.5e-13 49.3 0.1 3.5 4 0 0 4 4 4 1 FERM N-terminal domain DUF4613 PF15390.1 EMC77082.1 - 7 4.6 14.4 9.6 4.2 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Ribosomal_S17 PF00366.15 EMC77083.1 - 3.9e-09 36.4 0.2 9.1e-09 35.2 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein S17 NIPSNAP PF07978.8 EMC77084.1 - 9e-38 128.3 0.6 1.3e-31 108.6 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP HAD PF12710.2 EMC77085.1 - 2.4e-18 67.0 0.0 5.3e-18 65.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC77085.1 - 1.1e-13 52.1 0.4 2.6e-12 47.6 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC77085.1 - 3.5e-06 27.3 0.0 7.7e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EMC77085.1 - 1.2e-05 24.7 0.0 2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 EMC77085.1 - 2.2e-05 23.7 0.0 7e-05 22.1 0.0 1.7 2 1 0 2 2 2 1 Putative Phosphatase Acid_phosphat_B PF03767.9 EMC77085.1 - 0.00073 18.9 0.0 0.044 13.1 0.0 2.1 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.7 EMC77085.1 - 0.0068 16.0 0.1 0.36 10.3 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC77085.1 - 0.014 15.0 0.0 0.044 13.4 0.0 1.9 1 1 0 2 2 2 0 HAD-hyrolase-like PFK PF00365.15 EMC77085.1 - 0.052 12.4 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase StbA PF06406.6 EMC77085.1 - 0.062 12.2 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 StbA protein FGE-sulfatase PF03781.11 EMC77086.1 - 3.6e-59 200.2 4.7 4.2e-59 200.0 3.3 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Pkinase PF00069.20 EMC77087.1 - 2.6e-77 259.4 0.0 3.2e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77087.1 - 6.3e-33 113.9 0.0 8.1e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC77087.1 - 3.2e-10 39.4 0.0 3.2e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EMC77087.1 - 1.6e-06 27.3 0.1 2.9e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC77087.1 - 1.7e-05 24.6 0.1 0.17 11.5 0.2 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EMC77087.1 - 4.2e-05 22.9 1.1 7.5e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EMC77087.1 - 0.0042 16.6 0.2 0.0066 16.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EMC77087.1 - 0.012 15.0 0.1 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CHCH PF06747.8 EMC77088.1 - 4.6e-07 29.5 7.9 6.7e-07 29.0 5.5 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 EMC77088.1 - 0.081 12.9 14.7 0.31 11.0 10.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Med3 PF11593.3 EMC77088.1 - 0.96 8.6 6.5 1.2 8.3 4.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal VKOR PF07884.9 EMC77089.1 - 5.5e-21 74.8 10.2 6.1e-21 74.7 7.1 1.0 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Claudin_2 PF13903.1 EMC77089.1 - 0.049 13.3 4.9 0.056 13.1 3.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Yip1 PF04893.12 EMC77089.1 - 4.2 6.8 13.9 7.2 6.0 9.7 1.4 1 1 0 1 1 1 0 Yip1 domain SPC25 PF06703.6 EMC77089.1 - 5.1 6.6 9.9 10 5.6 6.8 1.5 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2207 PF09972.4 EMC77089.1 - 5.6 5.4 7.0 6.3 5.2 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_2_C PF02836.12 EMC77090.1 - 5.7e-101 337.3 0.0 7.3e-101 336.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EMC77090.1 - 3.6e-32 111.2 0.1 6.1e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EMC77090.1 - 2.5e-06 27.8 1.0 1.4e-05 25.4 0.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Cellulase-like PF12876.2 EMC77090.1 - 0.0049 17.2 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like RNA_pol_Rpb4 PF03874.11 EMC77091.1 - 5e-27 94.2 3.7 6.1e-27 93.9 2.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Muted PF14942.1 EMC77091.1 - 0.0085 15.9 1.9 0.018 14.8 0.1 2.1 1 1 1 2 2 2 1 Organelle biogenesis, Muted-like protein Sulfotransfer_3 PF13469.1 EMC77092.1 - 2.6e-14 54.4 0.1 4.1e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EMC77092.1 - 2e-08 33.8 0.1 1.9e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain BTB_2 PF02214.17 EMC77093.1 - 8.7e-20 70.7 0.0 5.3e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain VPS9 PF02204.13 EMC77094.1 - 2.4e-30 104.5 0.0 7.4e-30 103.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-A20 PF01754.11 EMC77094.1 - 4.7e-12 45.2 5.3 9.6e-12 44.2 3.7 1.6 1 0 0 1 1 1 1 A20-like zinc finger DUF501 PF04417.7 EMC77094.1 - 0.054 13.3 4.2 1.7 8.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF501) TMEM219 PF14940.1 EMC77095.1 - 1.5e-96 321.7 1.1 1.9e-96 321.4 0.7 1.1 1 0 0 1 1 1 1 Transmembrane 219 T2SK PF03934.8 EMC77097.1 - 0.00064 18.9 1.4 0.0019 17.4 0.2 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K LRR_4 PF12799.2 EMC77097.1 - 0.0014 18.2 2.2 0.0086 15.6 0.2 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC77097.1 - 0.025 14.5 3.6 0.21 11.7 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 EMC77097.1 - 0.033 14.3 0.3 0.29 11.4 0.2 2.7 1 0 0 1 1 1 0 Leucine rich repeat UCH PF00443.24 EMC77097.1 - 0.061 12.4 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase LRR_1 PF00560.28 EMC77097.1 - 0.42 10.8 6.6 1.5 9.1 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat SH3_2 PF07653.12 EMC77098.1 - 1.8e-24 84.9 1.2 1.3e-11 43.8 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 EMC77098.1 - 9.5e-19 66.5 0.4 4e-15 54.9 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.19 EMC77098.1 - 6.6e-18 64.2 0.0 2.2e-17 62.5 0.0 1.9 1 1 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 EMC77098.1 - 3.5e-14 52.0 2.5 1e-10 41.0 0.1 3.0 4 0 0 4 4 4 2 Variant SH3 domain 14-3-3 PF00244.15 EMC77099.1 - 6.3e-108 359.2 0.4 7.5e-108 359.0 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein MCM_N PF14551.1 EMC77099.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 1 0 1 1 1 0 MCM N-terminal domain Myosin_head PF00063.16 EMC77100.1 - 1.6e-239 796.6 4.1 2.9e-239 795.7 2.9 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EMC77100.1 - 1e-38 132.6 1.5 2e-38 131.7 1.0 1.5 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 EMC77100.1 - 0.00013 21.2 15.4 0.0033 16.9 0.7 3.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EMC77100.1 - 0.0023 18.0 0.1 0.015 15.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EMC77100.1 - 0.0085 15.2 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EMC77100.1 - 0.038 14.8 0.0 0.17 12.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.18 EMC77101.1 - 3.9e-24 85.9 0.1 5.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CALCOCO1 PF07888.6 EMC77101.1 - 1.2e-09 36.9 0.2 1.9e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like IP_trans PF02121.13 EMC77102.1 - 1.3e-127 424.2 4.4 1.5e-127 424.0 3.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PROCN PF08083.6 EMC77103.1 - 4.9e-224 743.2 6.7 8.5e-224 742.4 4.7 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EMC77103.1 - 2.7e-129 429.3 0.7 4.6e-129 428.5 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EMC77103.1 - 5.6e-94 311.8 2.2 1.1e-93 310.9 1.5 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EMC77103.1 - 1.1e-81 271.8 3.3 1.1e-81 271.8 2.3 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EMC77103.1 - 2.4e-70 234.4 0.0 5.7e-70 233.2 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EMC77103.1 - 4.3e-52 175.0 0.0 9.9e-52 173.9 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EMC77103.1 - 8.3e-46 153.7 0.6 2.1e-45 152.5 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EMC77103.1 - 6.3e-14 51.7 0.0 3.2e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TRAM_LAG1_CLN8 PF03798.11 EMC77105.1 - 2.7e-19 69.5 11.3 3.1e-19 69.3 7.8 1.0 1 0 0 1 1 1 1 TLC domain Pyr_redox_2 PF07992.9 EMC77106.1 - 9.9e-29 100.6 0.0 2.3e-28 99.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EMC77106.1 - 6.8e-14 51.2 0.1 1.3e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Reductase_C PF14759.1 EMC77106.1 - 5.1e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal Pyr_redox PF00070.22 EMC77106.1 - 5.2e-06 26.7 1.1 0.27 11.6 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EMC77106.1 - 9.2e-06 25.3 0.0 3.5e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain DAO PF01266.19 EMC77106.1 - 7.8e-05 21.7 0.1 0.0032 16.4 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC77106.1 - 0.00076 18.4 0.0 3.2 6.5 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 EMC77106.1 - 0.035 12.5 0.1 3.5 6.0 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.1 EMC77106.1 - 0.055 13.4 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Beach PF02138.13 EMC77107.1 - 1.2e-60 205.3 0.1 3.2e-60 203.8 0.0 1.7 1 1 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EMC77107.1 - 1.3e-14 53.3 12.3 1e-07 31.5 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EMC77107.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.3 EMC77107.1 - 0.027 12.6 0.0 0.066 11.3 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Serpin PF00079.15 EMC77108.1 - 4.5e-87 292.6 0.5 5.1e-87 292.4 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC77109.1 - 2.4e-85 286.9 0.1 2.8e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) SET PF00856.23 EMC77110.1 - 2.1e-16 60.6 0.0 5.3e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 EMC77110.1 - 1.1e-09 38.0 0.6 0.00016 21.5 0.2 3.9 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMC77110.1 - 2.9e-08 33.2 1.1 0.0022 17.5 0.2 4.3 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EMC77110.1 - 2.4e-07 30.1 5.4 0.0065 16.2 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat zf-MYND PF01753.13 EMC77110.1 - 1.7e-06 27.7 14.7 1.7e-06 27.7 10.2 3.5 3 0 0 3 3 2 1 MYND finger Apc3 PF12895.2 EMC77110.1 - 7.7e-06 25.9 6.9 0.044 13.9 0.0 3.6 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EMC77110.1 - 3.3e-05 23.6 0.1 0.00044 20.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC77110.1 - 9.2e-05 21.9 2.3 0.0027 17.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC77110.1 - 0.00015 21.2 0.2 0.082 12.5 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC77110.1 - 0.00062 20.3 2.2 1.2 9.8 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC77110.1 - 0.0011 19.4 4.0 0.16 12.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC77110.1 - 0.065 13.0 0.0 0.45 10.4 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMC77110.1 - 0.16 12.4 12.2 0.17 12.4 0.6 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC77110.1 - 0.48 10.7 5.1 9.9 6.5 0.1 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC77110.1 - 0.68 10.5 2.4 32 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Rep_fac-A_C PF08646.5 EMC77111.1 - 3.9e-54 182.3 11.9 9e-50 168.1 5.4 2.9 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EMC77111.1 - 4e-27 93.9 0.1 7.5e-27 93.0 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EMC77111.1 - 1.1e-13 50.7 0.5 5.7e-12 45.3 0.0 3.2 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 EMC77111.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF223 LRR_8 PF13855.1 EMC77112.1 - 2.7e-29 100.7 14.7 2.8e-14 52.6 0.3 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC77112.1 - 5.4e-17 60.9 9.4 3.2e-06 26.6 0.7 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77112.1 - 9.8e-10 37.1 16.7 1.1 9.5 0.0 8.0 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_5 PF13306.1 EMC77112.1 - 9.3e-07 28.6 0.0 0.0058 16.3 0.0 3.5 3 1 1 4 4 4 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC77112.1 - 5.5e-06 25.7 15.6 6.2 7.4 0.0 7.3 7 1 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 EMC77112.1 - 0.0037 16.8 0.2 0.075 12.5 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EMC77112.1 - 0.13 12.4 14.8 9.1 6.7 0.6 6.3 6 1 1 7 7 7 0 Leucine Rich repeat DUF566 PF04484.7 EMC77112.1 - 0.45 9.9 4.4 0.64 9.4 3.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) LRRNT PF01462.13 EMC77112.1 - 0.51 9.8 7.4 0.15 11.5 1.9 2.7 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Diphthamide_syn PF01866.12 EMC77113.1 - 6.3e-104 347.4 0.0 7.4e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein EST1_DNA_bind PF10373.4 EMC77114.1 - 1.6e-78 263.7 0.0 3.1e-78 262.8 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.1 EMC77114.1 - 3e-23 82.3 1.6 6.9e-23 81.2 0.0 2.6 2 0 0 2 2 2 1 PIN domain EST1 PF10374.4 EMC77114.1 - 5.8e-22 78.0 0.3 1.6e-21 76.6 0.2 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EMC77114.1 - 0.021 14.4 4.7 0.021 14.4 2.0 2.0 2 0 0 2 2 2 0 TPR repeat PALP PF00291.20 EMC77115.1 - 1.8e-69 234.2 0.9 2.5e-69 233.8 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3798 PF12683.2 EMC77115.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) DUF663 PF04950.7 EMC77116.1 - 6.7e-118 392.9 0.1 1.3e-117 392.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMC77116.1 - 2.6e-20 71.7 0.0 5.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Bd3614_N PF14442.1 EMC77116.1 - 0.18 11.7 5.5 0.42 10.5 3.8 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF525 PF04379.9 EMC77117.1 - 2.7e-25 88.1 0.0 4.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF525) YccV-like PF08755.6 EMC77117.1 - 5.2e-05 23.1 1.2 0.00026 20.8 0.3 2.6 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Vma12 PF11712.3 EMC77118.1 - 2.9e-23 82.1 0.1 3.7e-23 81.8 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3989 PF13150.1 EMC77118.1 - 0.11 11.9 1.1 0.22 10.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3989) MFS_1 PF07690.11 EMC77119.1 - 2.1e-06 26.6 13.6 2.1e-06 26.6 9.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4149 PF13664.1 EMC77119.1 - 1.3 9.0 11.6 1.7 8.7 3.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Na_sulph_symp PF00939.14 EMC77120.1 - 1.3e-142 475.9 25.9 1.6e-142 475.7 18.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMC77120.1 - 8.6e-19 67.3 34.5 2.8e-10 39.3 5.8 3.1 3 0 0 3 3 3 3 Citrate transporter Fork_head PF00250.13 EMC77121.1 - 2.2e-30 104.5 0.5 2.2e-30 104.5 0.4 2.1 2 0 0 2 2 2 1 Fork head domain GMP_PDE_delta PF05351.6 EMC77122.1 - 2e-81 271.3 3.4 2.2e-81 271.2 2.3 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IIGP PF05049.8 EMC77122.1 - 0.071 11.9 0.2 0.095 11.5 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Glycolytic PF00274.14 EMC77123.1 - 4.6e-168 558.0 0.0 5.4e-168 557.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I YjcQ PF09639.5 EMC77123.1 - 0.075 13.1 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 YjcQ protein Pox_A_type_inc PF04508.7 EMC77124.1 - 0.017 14.8 1.0 0.092 12.5 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CALCOCO1 PF07888.6 EMC77124.1 - 0.04 12.2 11.0 0.041 12.1 7.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tail_P2_I PF09684.5 EMC77124.1 - 0.044 13.3 0.2 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) MAD PF05557.8 EMC77124.1 - 0.051 11.6 8.9 0.071 11.2 6.2 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein PHY PF00360.15 EMC77124.1 - 0.065 12.3 0.1 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Phytochrome region Phage-tail_1 PF09097.5 EMC77124.1 - 0.084 12.4 0.0 0.094 12.2 0.0 1.1 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 APG6 PF04111.7 EMC77124.1 - 0.089 11.8 8.4 0.099 11.6 5.6 1.2 1 1 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 EMC77124.1 - 0.16 11.8 8.3 0.21 11.5 5.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3226 PF11536.3 EMC77124.1 - 0.19 11.1 2.4 0.19 11.1 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3226) DUF2968 PF11180.3 EMC77124.1 - 0.64 9.3 5.9 0.7 9.2 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GAS PF13851.1 EMC77124.1 - 3.8 6.6 15.8 4.3 6.4 11.0 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EMC77124.1 - 9.4 6.6 9.9 99 3.3 6.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) WEMBL PF05701.6 EMC77125.1 - 0.059 11.8 7.5 0.08 11.3 5.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light APG6 PF04111.7 EMC77125.1 - 0.17 10.8 7.8 0.25 10.3 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CTD PF12815.2 EMC77125.1 - 0.18 12.2 8.8 0.27 11.6 6.1 1.3 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Hemerythrin PF01814.18 EMC77125.1 - 0.24 11.5 3.7 0.38 10.9 2.6 1.4 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF972 PF06156.8 EMC77125.1 - 1.5 9.1 6.8 2.1 8.7 4.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EMC77125.1 - 3.7 8.0 5.5 4.5 7.7 1.0 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.20 EMC77126.1 - 2.7e-38 131.6 0.0 2.9e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77126.1 - 3.6e-18 65.5 0.0 4e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC77126.1 - 6.1e-06 25.4 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC77126.1 - 0.0053 15.8 0.1 0.0064 15.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMC77126.1 - 0.021 13.7 0.0 0.074 11.8 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 EMC77126.1 - 0.077 12.7 0.2 0.092 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1025 PF06262.6 EMC77126.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase MIR PF02815.14 EMC77127.1 - 4.2e-07 29.6 0.0 7.4e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 MIR domain SH2_2 PF14633.1 EMC77128.1 - 9.5e-112 371.4 0.5 9.5e-112 371.4 0.3 2.4 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 EMC77128.1 - 2e-71 238.4 0.0 5.4e-71 237.0 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EMC77128.1 - 3e-54 182.0 1.2 3e-54 182.0 0.8 3.7 2 1 0 3 3 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EMC77128.1 - 2.5e-53 178.5 0.1 6e-53 177.3 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EMC77128.1 - 1.4e-46 157.4 1.9 3.9e-46 155.9 1.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EMC77128.1 - 5.4e-13 48.9 31.3 5.4e-13 48.9 21.7 7.9 6 1 2 8 8 6 2 Acidic N-terminal SPT6 Tex_N PF09371.5 EMC77128.1 - 3.1e-08 33.1 0.0 0.00068 18.9 0.0 2.9 2 0 0 2 2 2 2 Tex-like protein N-terminal domain SH2 PF00017.19 EMC77128.1 - 2.1e-06 27.4 0.0 5.9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EMC77128.1 - 3.5e-06 26.8 0.0 2.1e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.18 EMC77128.1 - 3.9e-06 26.8 0.1 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain zf-C2H2_4 PF13894.1 EMC77128.1 - 0.12 12.7 0.3 0.38 11.2 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EMC77128.1 - 0.2 11.2 0.4 0.51 9.9 0.3 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Phospholip_A2_2 PF05826.7 EMC77129.1 - 7.4e-20 70.7 2.2 1.5e-19 69.8 1.5 1.5 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 EMC77129.1 - 0.039 14.1 10.0 0.28 11.4 6.3 2.4 1 1 0 1 1 1 0 Phospholipase A2 RloB PF13707.1 EMC77129.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.4 2 0 0 2 2 2 0 RloB-like protein SR-25 PF10500.4 EMC77129.1 - 0.16 11.3 11.6 0.11 11.9 2.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NST1 PF13945.1 EMC77129.1 - 0.99 9.4 6.6 0.1 12.6 0.7 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator BLVR PF06375.6 EMC77129.1 - 2.3 8.0 11.0 0.14 11.9 1.6 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Ribosomal_L23 PF00276.15 EMC77130.1 - 1.3e-20 73.1 2.4 1.3e-20 73.1 1.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EMC77130.1 - 6.6e-16 58.0 11.7 6.6e-16 58.0 8.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain zf-ISL3 PF14690.1 EMC77130.1 - 0.018 15.0 2.3 0.04 13.9 1.6 1.6 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TRAM_LAG1_CLN8 PF03798.11 EMC77131.1 - 7.7e-19 68.0 13.9 8.4e-19 67.9 9.6 1.0 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.20 EMC77132.1 - 5.9e-65 219.0 0.0 8.9e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.13 EMC77132.1 - 2.1e-54 181.4 18.9 2.4e-14 53.2 0.5 8.0 7 2 1 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.12 EMC77132.1 - 9.3e-46 155.9 0.0 1.8e-45 155.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1_2 PF13540.1 EMC77132.1 - 1.9e-19 68.7 29.8 6.1e-06 25.7 0.2 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.1 EMC77132.1 - 3.9e-05 22.7 0.0 5.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC77132.1 - 0.037 13.7 0.5 0.3 10.7 0.3 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EMC77132.1 - 0.19 10.7 0.2 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM222A PF15258.1 EMC77133.1 - 1e-247 823.3 36.3 1.5e-247 822.8 25.2 1.2 1 0 0 1 1 1 1 Protein family of FAM222A MMR_HSR1 PF01926.18 EMC77134.1 - 1.5e-19 70.0 0.0 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC77134.1 - 7.2e-11 42.1 0.2 9.4e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.13 EMC77134.1 - 5e-10 38.8 0.0 7.6e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EMC77134.1 - 5.2e-10 39.8 0.0 8.8e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC77134.1 - 4.8e-09 35.9 0.0 1.5e-06 27.7 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EMC77134.1 - 8.8e-09 34.7 0.0 1.9e-08 33.6 0.0 1.5 1 1 1 2 2 2 1 AIG1 family KH_2 PF07650.12 EMC77134.1 - 1.8e-06 27.3 0.0 3.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 KH domain Ras PF00071.17 EMC77134.1 - 4.5e-05 22.9 0.0 0.00015 21.2 0.0 1.7 1 1 0 1 1 1 1 Ras family cobW PF02492.14 EMC77134.1 - 0.00021 20.7 0.4 0.0035 16.8 0.0 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EMC77134.1 - 0.00059 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GBP PF02263.14 EMC77134.1 - 0.00059 18.9 0.1 0.041 12.9 0.1 2.6 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain ATP_bind_1 PF03029.12 EMC77134.1 - 0.00082 18.9 0.2 0.0056 16.2 0.1 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein KH_1 PF00013.24 EMC77134.1 - 0.00082 18.9 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 KH domain AAA_28 PF13521.1 EMC77134.1 - 0.0011 18.9 0.1 0.009 15.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC77134.1 - 0.0013 19.5 0.0 0.0035 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain Arf PF00025.16 EMC77134.1 - 0.0047 16.1 0.3 0.065 12.4 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC77134.1 - 0.021 13.5 0.2 0.87 8.1 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 EMC77134.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 EMC77134.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KH_3 PF13014.1 EMC77134.1 - 0.079 12.6 0.3 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 KH domain Band_7 PF01145.20 EMC77135.1 - 1.6e-19 70.4 0.1 1.6e-19 70.4 0.0 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMC77135.1 - 0.012 15.1 0.2 0.012 15.1 0.1 1.9 2 0 0 2 2 2 0 SPFH domain-Band 7 family Sds3 PF08598.6 EMC77135.1 - 3.5 7.0 9.8 6.7 6.1 6.8 1.6 1 0 0 1 1 1 0 Sds3-like DUF1492 PF07374.6 EMC77135.1 - 4.9 7.3 9.8 1.6 8.8 4.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1492) PHD PF00628.24 EMC77136.1 - 8.3e-08 31.8 10.6 2.4e-07 30.3 2.9 3.4 3 0 0 3 3 3 1 PHD-finger FHA PF00498.21 EMC77136.1 - 0.0012 18.9 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 FHA domain C1_1 PF00130.17 EMC77136.1 - 0.0051 16.5 1.3 0.0051 16.5 0.9 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EMC77136.1 - 0.16 11.3 0.1 0.16 11.3 0.0 4.6 5 0 0 5 5 5 0 PHD-finger RebB PF11747.3 EMC77136.1 - 0.68 9.8 6.5 0.17 11.7 0.7 2.4 2 0 0 2 2 2 0 Killing trait Sushi PF00084.15 EMC77137.1 - 3.1e-30 104.2 15.2 6e-10 39.3 0.4 3.4 3 0 0 3 3 3 3 Sushi domain (SCR repeat) CUB PF00431.15 EMC77137.1 - 9.9e-16 57.7 0.0 9.3e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 CUB domain SKG6 PF08693.5 EMC77137.1 - 0.1 11.9 1.0 0.19 11.0 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain cEGF PF12662.2 EMC77137.1 - 0.43 10.2 7.7 8.6 6.1 0.1 3.6 3 1 0 3 3 3 0 Complement Clr-like EGF-like SR-25 PF10500.4 EMC77139.1 - 0.001 18.6 47.0 0.0018 17.7 32.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Rtf2 PF04641.7 EMC77139.1 - 0.15 11.2 18.4 0.23 10.6 12.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.1 EMC77139.1 - 0.18 11.5 14.4 0.24 11.1 10.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TFIIF_alpha PF05793.7 EMC77139.1 - 0.41 8.9 30.4 0.6 8.4 21.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ELL PF10390.4 EMC77139.1 - 1 8.5 16.8 1.3 8.1 11.6 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL FLO_LFY PF01698.11 EMC77139.1 - 1.3 7.8 9.1 1.5 7.5 6.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 EMC77139.1 - 1.3 7.9 3.4 1.3 7.9 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 EMC77139.1 - 1.4 8.7 8.7 1.9 8.2 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.14 EMC77139.1 - 1.4 7.4 8.5 1.7 7.2 5.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Macoilin PF09726.4 EMC77139.1 - 1.5 7.0 19.6 1.9 6.7 13.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 EMC77139.1 - 5.1 4.6 12.0 5.8 4.4 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DNA_pol_viral_N PF00242.12 EMC77139.1 - 9.3 5.1 15.8 14 4.5 10.9 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Crystall PF00030.14 EMC77140.1 - 2.5e-31 107.3 0.3 3.1e-31 107.1 0.2 1.1 1 0 0 1 1 1 1 Beta/Gamma crystallin NUFIP2 PF15293.1 EMC77141.1 - 8.5e-292 969.3 22.1 9.6e-292 969.1 15.3 1.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Pkinase PF00069.20 EMC77142.1 - 2.7e-65 220.1 0.0 2.7e-65 220.1 0.0 2.5 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77142.1 - 9.8e-45 152.6 1.3 1.9e-44 151.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC77142.1 - 0.0026 17.5 1.9 0.0051 16.5 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family AAA-ATPase_like PF09820.4 EMC77142.1 - 0.005 16.0 6.1 0.005 16.0 4.3 2.8 2 0 0 2 2 2 1 Predicted AAA-ATPase Abhydrolase_6 PF12697.2 EMC77143.1 - 0.011 15.5 2.7 0.088 12.6 0.6 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family GPCR_chapero_1 PF11904.3 EMC77144.1 - 1e-109 366.3 0.0 1.3e-109 366.0 0.0 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 EMC77144.1 - 3.9e-13 49.5 0.0 8.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC77144.1 - 8.4e-11 41.1 0.0 8e-09 34.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EMC77144.1 - 3.9e-09 36.4 0.1 1.6e-08 34.5 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC77144.1 - 7e-08 32.7 0.0 1.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77144.1 - 3.3e-07 29.9 0.0 0.00018 21.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat UIM PF02809.15 EMC77144.1 - 0.47 10.1 10.7 0.89 9.3 1.7 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif DSPc PF00782.15 EMC77146.1 - 6e-35 119.7 0.0 1.9e-34 118.1 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 EMC77146.1 - 2.8e-15 55.8 3.8 5.5e-15 54.8 2.7 1.5 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.22 EMC77146.1 - 0.01 15.1 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein-tyrosine phosphatase EF-hand_6 PF13405.1 EMC77147.1 - 0.00089 18.9 1.9 0.0026 17.5 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EMC77147.1 - 0.0035 17.4 0.2 0.11 12.5 0.0 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC77147.1 - 0.015 14.5 0.0 0.059 12.6 0.0 2.1 1 0 0 1 1 1 0 EF hand Tfb2 PF03849.9 EMC77147.1 - 0.018 13.6 1.7 1.2 7.6 0.0 3.1 3 0 0 3 3 3 0 Transcription factor Tfb2 RFC1 PF08519.7 EMC77147.1 - 0.037 13.7 0.1 0.18 11.5 0.0 2.0 1 1 1 2 2 2 0 Replication factor RFC1 C terminal domain UCH PF00443.24 EMC77147.1 - 0.1 11.6 0.1 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase SPARC_Ca_bdg PF10591.4 EMC77147.1 - 0.81 9.7 4.1 0.44 10.5 0.5 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CENP-Q PF13094.1 EMC77147.1 - 0.88 9.5 6.9 15 5.5 4.8 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2040 PF09745.4 EMC77148.1 - 5.1e-36 123.3 28.1 5.1e-36 123.3 19.5 5.4 2 1 4 6 6 6 1 Coiled-coil domain-containing protein 55 (DUF2040) SNF PF00209.13 EMC77149.1 - 3.5e-227 755.0 36.5 4e-227 754.8 25.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 5HT_transporter PF03491.8 EMC77149.1 - 1.3e-05 25.2 1.7 3e-05 24.0 1.2 1.6 1 0 0 1 1 1 1 Serotonin (5-HT) neurotransmitter transporter, N-terminus Peptidase_C1_2 PF03051.10 EMC77150.1 - 5.8e-193 641.3 3.5 6.5e-193 641.1 2.4 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EMC77150.1 - 7.1e-07 29.3 1.4 0.0072 16.2 0.1 2.7 3 0 0 3 3 3 2 Papain family cysteine protease DUF1126 PF06565.7 EMC77150.1 - 0.062 12.7 0.1 0.81 9.2 0.0 2.5 1 1 1 2 2 2 0 Repeat of unknown function (DUF1126) Ig_2 PF13895.1 EMC77151.1 - 2.2e-20 72.5 4.9 7.5e-15 54.8 1.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC77151.1 - 1.6e-16 59.9 3.8 8.1e-15 54.4 0.8 2.3 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC77151.1 - 1.9e-13 50.6 6.2 4.4e-08 33.4 0.8 2.5 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC77151.1 - 6.5e-13 48.6 6.9 4.4e-10 39.5 0.6 3.4 2 1 1 3 3 3 2 Immunoglobulin domain V-set PF07686.12 EMC77151.1 - 4.1e-12 45.9 7.1 4.6e-11 42.6 1.7 3.1 1 1 1 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC77151.1 - 1e-06 28.5 4.2 9.3e-05 22.2 0.9 2.9 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Gemini_C4 PF01492.12 EMC77151.1 - 0.031 13.9 1.0 0.16 11.6 0.7 2.0 1 1 0 1 1 1 0 Geminivirus C4 protein Herpes_gE PF02480.11 EMC77151.1 - 0.14 10.3 1.9 0.53 8.4 1.2 2.0 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Phage_holin PF04688.8 EMC77151.1 - 8.6 5.9 6.9 0.68 9.5 0.8 2.1 2 0 0 2 2 2 0 Phage lysis protein, holin V-SNARE_C PF12352.3 EMC77152.1 - 5.4e-22 77.6 3.6 5.4e-22 77.6 2.5 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMC77152.1 - 0.0024 17.5 1.1 0.014 15.0 0.2 2.2 2 0 0 2 2 2 1 Sec20 HLH PF00010.21 EMC77153.1 - 6.2e-10 38.6 2.5 1.1e-09 37.8 1.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RhoGEF PF00621.15 EMC77154.1 - 1.4e-31 109.7 0.6 4.1e-31 108.2 0.4 1.8 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.24 EMC77154.1 - 1.3e-17 63.8 0.5 2.1e-17 63.1 0.3 1.4 1 0 0 1 1 1 1 PH domain PH_5 PF15405.1 EMC77154.1 - 0.062 13.2 0.5 0.22 11.4 0.3 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Tim17 PF02466.14 EMC77155.1 - 1.6e-38 131.6 6.4 1.8e-38 131.4 4.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CH PF00307.26 EMC77156.1 - 5.1e-24 84.3 0.8 1.9e-23 82.5 0.1 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC77156.1 - 9.3e-09 34.8 0.5 3.5e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 CAMSAP CH domain TPR_MLP1_2 PF07926.7 EMC77156.1 - 0.00023 20.8 5.7 0.00023 20.8 3.9 6.3 3 1 3 6 6 6 3 TPR/MLP1/MLP2-like protein 7tm_1 PF00001.16 EMC77157.1 - 6.6e-63 212.2 17.5 8.1e-63 211.9 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77157.1 - 1.2e-12 47.6 18.8 1.8e-08 33.8 3.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Git3_C PF11970.3 EMC77157.1 - 0.035 13.8 0.3 0.12 12.1 0.2 2.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term 7TM_GPCR_Srx PF10328.4 EMC77157.1 - 0.2 10.7 26.1 0.018 14.1 12.6 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx SWIM PF04434.12 EMC77158.1 - 5.9e-07 28.8 3.3 9.3e-07 28.1 2.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger TPR_12 PF13424.1 EMC77159.1 - 7.5e-27 93.0 17.7 1.2e-14 54.0 0.6 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMC77159.1 - 1.9e-13 49.1 13.4 0.0039 16.9 0.2 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMC77159.1 - 2.1e-13 49.6 18.3 0.00066 19.5 0.0 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMC77159.1 - 2.1e-12 46.5 21.8 8e-07 28.6 1.2 3.8 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EMC77159.1 - 3.3e-11 42.2 15.6 0.0056 16.2 0.4 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC77159.1 - 3.7e-09 36.4 12.5 1.2 9.9 0.1 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC77159.1 - 2e-08 34.6 12.4 1.9e-05 25.1 1.4 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC77159.1 - 4.3e-07 29.2 16.7 0.39 10.5 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC77159.1 - 8.1e-07 29.3 21.5 0.0011 19.2 0.9 4.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC77159.1 - 8.4e-07 28.3 11.3 0.15 11.8 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC77159.1 - 4e-06 26.6 9.1 0.68 10.2 0.0 6.0 6 1 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC77159.1 - 3.5e-05 23.8 6.0 0.00063 19.8 0.9 3.6 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EMC77159.1 - 0.0025 18.0 0.0 2.4 8.8 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat MMS19_C PF12460.3 EMC77159.1 - 0.022 13.4 1.8 0.028 13.1 1.1 1.3 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal PE-PPE PF08237.6 EMC77159.1 - 0.044 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain Apc5 PF12862.2 EMC77159.1 - 0.048 13.5 11.1 0.065 13.0 0.6 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 PPR PF01535.15 EMC77159.1 - 0.17 11.8 1.0 3.1 7.9 0.0 3.4 4 0 0 4 4 4 0 PPR repeat Sec16_C PF12931.2 EMC77159.1 - 0.39 10.4 9.0 0.12 12.0 3.3 1.8 1 1 1 2 2 2 0 Sec23-binding domain of Sec16 TPR_6 PF13174.1 EMC77159.1 - 0.9 10.1 15.4 25 5.5 0.1 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 EMC77160.1 - 2e-18 66.1 0.3 1.5e-11 44.1 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain PIG-L PF02585.12 EMC77161.1 - 8.1e-10 39.2 0.1 1.5e-09 38.4 0.0 1.5 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase GFA PF04828.9 EMC77162.1 - 2.1e-12 46.7 1.4 2.1e-12 46.7 1.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.14 EMC77162.1 - 0.028 14.2 0.4 0.028 14.2 0.3 2.0 3 0 0 3 3 3 0 Ribosomal protein L37e Glyco_hydro_67N PF03648.9 EMC77163.1 - 0.065 13.2 0.0 54 3.8 0.0 3.7 4 0 0 4 4 4 0 Glycosyl hydrolase family 67 N-terminus DUF296 PF03479.10 EMC77163.1 - 0.12 12.0 0.3 47 3.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF296) ubiquitin PF00240.18 EMC77164.1 - 1.4e-134 437.6 18.1 1.2e-34 117.4 0.3 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EMC77164.1 - 4.2e-78 257.0 16.5 1.1e-19 69.8 0.3 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC77164.1 - 1.9e-26 92.1 6.2 3.6e-05 23.9 0.1 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMC77164.1 - 1.7e-18 66.8 0.1 0.0028 17.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMC77164.1 - 1.9e-14 53.4 2.2 0.077 12.8 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMC77164.1 - 2.8e-13 49.8 0.5 0.22 11.7 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EMC77164.1 - 9.4e-12 44.6 2.2 0.37 10.7 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG DUF2870 PF11069.3 EMC77164.1 - 4.6e-10 39.3 0.0 1.4 8.9 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EMC77164.1 - 1.1e-07 31.5 1.8 5.1 6.9 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain USP7_C2 PF14533.1 EMC77164.1 - 6.2e-06 25.7 3.8 5.3 6.4 0.0 4.0 1 1 1 4 4 4 3 Ubiquitin-specific protease C-terminal CTDII PF01556.13 EMC77164.1 - 0.00041 20.1 14.3 2.6 8.0 0.2 4.2 1 1 3 4 4 4 3 DnaJ C terminal domain FERM_N PF09379.5 EMC77164.1 - 0.0005 20.0 4.5 39 4.3 0.0 5.5 4 3 0 4 4 4 0 FERM N-terminal domain YfmQ PF10787.4 EMC77164.1 - 0.0019 17.5 0.5 48 3.2 0.0 4.0 4 0 0 4 4 4 0 Uncharacterised protein from bacillus cereus group Plexin_cytopl PF08337.7 EMC77164.1 - 0.0047 15.3 9.6 5.5 5.1 0.1 4.9 4 3 0 4 4 4 3 Plexin cytoplasmic RasGAP domain GABP-alpha PF11620.3 EMC77164.1 - 0.068 13.1 3.2 45 4.1 0.1 3.6 3 1 1 4 4 4 0 GA-binding protein alpha chain GDYXXLXY PF14345.1 EMC77164.1 - 0.094 12.5 0.8 2.1e+02 1.7 0.0 4.1 4 0 0 4 4 4 0 GDYXXLXY protein DUF3781 PF12636.2 EMC77164.1 - 0.28 11.1 4.6 1.5e+02 2.4 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) YajC PF02699.10 EMC77164.1 - 0.5 10.0 7.6 53 3.5 0.0 4.0 4 0 0 4 4 4 0 Preprotein translocase subunit Ion_trans PF00520.26 EMC77165.1 - 3e-05 23.3 18.9 3e-05 23.3 13.1 2.1 1 1 1 2 2 2 1 Ion transport protein DUF3635 PF12330.3 EMC77166.1 - 1.2e-23 83.0 1.1 2.7e-23 81.8 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 EMC77166.1 - 1e-07 31.3 0.1 3.8e-07 29.5 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.18 EMC77166.1 - 0.05 13.3 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family P2X_receptor PF00864.14 EMC77167.1 - 1.4e-127 425.5 0.0 1.6e-127 425.2 0.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor Rab5ip PF07019.7 EMC77168.1 - 7e-25 86.9 6.2 8.8e-25 86.6 4.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF606 PF04657.8 EMC77168.1 - 0.029 14.4 1.7 0.044 13.8 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF606 DUF4271 PF14093.1 EMC77168.1 - 0.041 13.5 3.9 0.048 13.3 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) PDZ PF00595.19 EMC77169.1 - 9.9e-20 70.5 0.2 1.2e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC77169.1 - 1.2e-11 44.3 0.3 1.7e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EMC77169.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.5 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain FGGY_N PF00370.16 EMC77170.1 - 9.7e-27 93.8 0.1 2e-25 89.5 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EMC77170.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF4445 PF14574.1 EMC77170.1 - 0.06 11.5 0.0 0.092 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) DUF1537 PF07005.6 EMC77170.1 - 0.15 11.7 2.5 0.92 9.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 Ank_2 PF12796.2 EMC77171.1 - 9.8e-27 93.1 8.5 2.1e-12 47.1 0.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC77171.1 - 2.5e-17 61.7 0.4 6e-05 22.6 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EMC77171.1 - 8.9e-14 50.2 0.1 0.00048 20.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EMC77171.1 - 1.5e-13 50.4 0.0 0.0086 16.3 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC77171.1 - 2.8e-10 40.4 1.2 0.0078 16.6 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) DUF2229 PF09989.4 EMC77171.1 - 0.068 12.6 0.3 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) AstE_AspA PF04952.9 EMC77172.1 - 9.9e-62 208.4 0.0 1.1e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family L_HGMIC_fpl PF10242.4 EMC77174.1 - 3.9e-14 53.0 0.4 4.7e-14 52.7 0.2 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein RGS PF00615.14 EMC77175.1 - 9.3e-31 106.3 2.0 2.9e-12 46.7 0.1 3.5 3 0 0 3 3 3 3 Regulator of G protein signaling domain WD40 PF00400.27 EMC77176.1 - 8e-90 291.8 19.0 7.6e-13 47.8 0.1 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EMC77176.1 - 8.6e-18 64.1 0.4 2.2e-17 62.7 0.1 1.9 3 0 0 3 3 3 1 NLE (NUC135) domain eIF2A PF08662.6 EMC77176.1 - 7.4e-08 32.3 0.1 0.22 11.2 0.0 3.8 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC77176.1 - 6.4e-07 27.8 5.8 0.57 8.2 0.1 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC77176.1 - 1.7e-05 23.7 5.2 0.52 8.9 0.3 4.5 2 2 2 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 EMC77176.1 - 2.4e-05 23.8 1.1 0.21 11.2 0.0 4.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EMC77176.1 - 0.00014 20.2 0.0 0.028 12.6 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3312) Gmad1 PF10647.4 EMC77176.1 - 0.00017 21.1 6.0 0.00019 20.9 0.3 2.7 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EMC77176.1 - 0.0006 18.2 0.0 0.079 11.2 0.0 3.0 3 0 0 3 3 3 1 Cytochrome D1 heme domain FAD_binding_9 PF08021.6 EMC77176.1 - 0.051 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Pkinase PF00069.20 EMC77177.1 - 3.2e-70 236.2 0.0 4.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 EMC77177.1 - 1.6e-52 178.1 4.2 2.5e-52 177.4 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 EMC77177.1 - 7e-49 166.2 0.0 1.1e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC77177.1 - 1.7e-06 27.2 0.0 3.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC77177.1 - 7.1e-06 25.4 0.1 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EMC77177.1 - 0.0018 17.2 0.0 0.0068 15.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EMC77177.1 - 0.0097 15.6 0.0 0.036 13.7 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Aldedh PF00171.17 EMC77178.1 - 1.8e-80 270.5 0.0 1.7e-51 174.9 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Aldedh PF00171.17 EMC77179.1 - 1.9e-85 286.9 0.0 2.2e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MatE PF01554.13 EMC77181.1 - 5.5e-47 159.3 25.6 3.5e-27 95.0 7.2 2.2 2 0 0 2 2 2 2 MatE Dispanin PF04505.7 EMC77181.1 - 0.015 14.8 1.0 0.015 14.8 0.7 3.0 2 0 0 2 2 2 0 Interferon-induced transmembrane protein 7tm_4 PF13853.1 EMC77183.1 - 5.4e-43 146.2 10.5 6.1e-43 146.0 7.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC77183.1 - 0.00011 21.4 7.6 0.00012 21.3 5.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 EMC77183.1 - 4.3 7.3 0.0 4.3 7.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) 7tm_4 PF13853.1 EMC77184.1 - 4.1e-30 104.4 12.8 4.1e-30 104.4 8.9 2.5 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC77184.1 - 2.2e-24 85.9 23.6 3.1e-24 85.4 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77184.1 - 1.2e-06 27.8 20.7 2.1e-06 27.1 14.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-C2H2_4 PF13894.1 EMC77185.1 - 4.1e-06 26.7 118.8 0.015 15.6 4.6 14.7 14 0 0 14 14 14 8 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC77185.1 - 7.2e-05 22.9 124.2 0.0015 18.7 5.2 14.7 15 0 0 15 15 15 10 Zinc finger, C2H2 type zf-met PF12874.2 EMC77185.1 - 0.003 17.7 1.4 0.003 17.7 0.9 10.0 10 0 0 10 10 10 2 Zinc-finger of C2H2 type Amino_oxidase PF01593.19 EMC77186.1 - 5.5e-164 546.5 0.0 6.7e-164 546.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EMC77186.1 - 3.8e-20 71.7 0.2 3.9e-19 68.5 0.0 2.6 3 0 0 3 3 3 1 SWIRM domain NAD_binding_8 PF13450.1 EMC77186.1 - 7.2e-15 54.7 0.5 1.5e-14 53.7 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC77186.1 - 9.6e-08 31.3 0.0 5.2e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC77186.1 - 3.6e-07 30.4 0.6 1.5e-05 25.3 0.2 3.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC77186.1 - 5.1e-05 22.2 1.7 5.7e-05 22.1 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC77186.1 - 7.5e-05 22.7 0.1 0.00026 20.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMC77186.1 - 0.0001 21.9 0.3 0.00023 20.7 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EMC77186.1 - 0.00059 18.9 0.5 0.001 18.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC77186.1 - 0.00062 19.8 2.0 0.0018 18.3 0.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC77186.1 - 0.00079 18.0 0.4 0.00079 18.0 0.3 2.2 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMC77186.1 - 0.0011 18.0 0.1 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMC77186.1 - 0.021 13.9 4.3 0.015 14.3 1.3 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EMC77186.1 - 0.022 13.9 0.2 0.083 12.0 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EMC77186.1 - 0.05 12.4 5.4 0.1 11.4 0.2 2.2 1 1 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.7 EMC77186.1 - 0.11 11.8 0.8 0.42 9.9 0.5 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF1465 PF07323.7 EMC77186.1 - 0.12 11.9 3.0 0.17 11.4 0.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1465) MutS_IV PF05190.13 EMC77186.1 - 0.22 11.6 3.5 1.3 9.2 0.4 2.6 2 0 0 2 2 2 0 MutS family domain IV Nnf1 PF03980.9 EMC77186.1 - 2.2 8.3 10.1 4.8 7.2 7.0 1.6 1 0 0 1 1 1 0 Nnf1 V_ATPase_I PF01496.14 EMC77186.1 - 3.2 5.4 5.6 5.5 4.7 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3782 PF12644.2 EMC77186.1 - 7.2 6.4 8.6 2.1e+03 -1.5 5.9 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Viral_P18 PF04521.8 EMC77186.1 - 7.7 5.9 8.0 2.4 7.6 2.6 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Snapin_Pallidin PF14712.1 EMC77186.1 - 8.6 6.7 10.4 4 7.8 2.9 2.4 1 1 0 2 2 2 0 Snapin/Pallidin HD_assoc PF13286.1 EMC77187.1 - 0.024 14.9 0.3 0.11 12.8 0.2 2.1 1 0 0 1 1 1 0 Phosphohydrolase-associated domain GAS PF13851.1 EMC77187.1 - 1.7 7.7 70.4 2.1 7.5 13.5 4.4 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding YvrJ PF12841.2 EMC77187.1 - 5.7 6.3 5.1 49 3.3 0.4 3.5 2 0 0 2 2 2 0 YvrJ protein family 7tm_1 PF00001.16 EMC77188.1 - 3.2e-86 288.6 13.7 3.9e-86 288.3 9.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77188.1 - 1.2e-11 44.3 9.2 2.9e-11 43.0 6.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC77188.1 - 0.00044 19.4 10.5 0.00044 19.4 7.3 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Ras PF00071.17 EMC77190.1 - 1.3e-50 170.9 0.1 1.5e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77190.1 - 3.4e-23 82.3 0.1 6.6e-23 81.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC77190.1 - 4.6e-07 29.2 0.0 6.6e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family ArgK PF03308.11 EMC77190.1 - 0.00035 19.4 0.9 0.059 12.1 0.3 2.1 2 0 0 2 2 2 2 ArgK protein SRPRB PF09439.5 EMC77190.1 - 0.0023 17.1 0.8 0.0088 15.2 0.5 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC77190.1 - 0.003 17.4 0.0 0.0046 16.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_32 PF13654.1 EMC77190.1 - 0.014 14.0 1.7 0.78 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMC77190.1 - 0.019 15.1 0.1 0.17 12.0 0.1 2.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EMC77190.1 - 0.057 12.6 1.5 0.11 11.6 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EMC77190.1 - 0.071 12.6 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMC77190.1 - 0.084 12.5 0.9 0.18 11.4 0.5 1.9 1 1 0 1 1 1 0 Archaeal ATPase DUF2408 PF10303.4 EMC77190.1 - 0.24 11.5 5.4 5.4 7.1 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) p25-alpha PF05517.7 EMC77191.1 - 2.2e-55 187.1 4.4 2.4e-55 186.9 3.0 1.0 1 0 0 1 1 1 1 p25-alpha RNA_pol_Rpb1_5 PF04998.12 EMC77191.1 - 0.0097 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 EF-hand_1 PF00036.27 EMC77191.1 - 0.13 11.6 0.9 0.83 9.1 0.0 2.7 3 0 0 3 3 3 0 EF hand ECH PF00378.15 EMC77192.1 - 1.2e-21 76.9 0.1 1.4e-21 76.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Vert_IL3-reg_TF PF06529.6 EMC77193.1 - 1.9e-212 704.2 18.6 2.6e-212 703.7 12.9 1.2 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor bZIP_2 PF07716.10 EMC77193.1 - 1.6e-14 53.4 9.3 1.6e-14 53.4 6.4 2.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC77193.1 - 3e-05 23.8 6.5 3e-05 23.8 4.5 3.7 3 0 0 3 3 3 1 bZIP transcription factor HALZ PF02183.13 EMC77193.1 - 0.69 9.6 3.7 4 7.2 0.6 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pkinase_Tyr PF07714.12 EMC77194.1 - 7.3e-87 290.7 0.0 9.6e-87 290.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77194.1 - 2.3e-40 138.4 0.0 3.3e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.13 EMC77194.1 - 1.4e-25 89.1 2.6 6e-25 87.1 1.7 2.2 2 0 0 2 2 2 1 Kringle domain Fz PF01392.17 EMC77194.1 - 8.5e-24 84.1 4.3 3.2e-23 82.3 3.0 2.1 1 0 0 1 1 1 1 Fz domain I-set PF07679.11 EMC77194.1 - 5e-18 64.7 0.0 9.5e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC77194.1 - 3.5e-09 36.6 1.1 1.5e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 EMC77194.1 - 4.5e-07 29.7 0.2 3.3e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC77194.1 - 7.7e-07 29.1 0.0 2.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC77194.1 - 2.2e-06 28.0 0.0 8.4e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain TMEM154 PF15102.1 EMC77194.1 - 0.0036 17.0 0.1 0.0095 15.6 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF2149 PF09919.4 EMC77194.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Aminotran_1_2 PF00155.16 EMC77195.1 - 3.9e-42 144.5 0.0 4.5e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PAD PF03068.10 EMC77195.1 - 0.0055 15.1 0.0 0.0078 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Cys_Met_Meta_PP PF01053.15 EMC77195.1 - 0.089 11.0 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PBD PF00786.23 EMC77196.1 - 1.8e-05 25.0 1.1 2.3e-05 24.6 0.7 1.4 1 1 0 1 1 1 1 P21-Rho-binding domain Complex1_LYR PF05347.10 EMC77197.1 - 6.7e-09 35.4 0.3 1.1e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC77197.1 - 9.7e-09 35.3 0.2 1.4e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 EMC77197.1 - 0.051 13.3 0.1 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) DUF2570 PF10828.3 EMC77197.1 - 0.098 12.2 0.3 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) HIT PF01230.18 EMC77198.1 - 2.8e-25 88.7 0.0 3e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMC77198.1 - 6.9e-18 64.9 0.0 7.7e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CHGN PF05679.11 EMC77199.1 - 1.5e-163 545.1 0.1 1.6e-163 544.9 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 EMC77199.1 - 1.3e-12 46.9 0.0 3.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC77199.1 - 4.9e-11 42.2 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC77199.1 - 0.056 13.1 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 UPF0258 PF06789.7 EMC77200.1 - 4.1e-29 101.6 0.0 5.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) Chordopox_A33R PF05966.7 EMC77200.1 - 0.079 11.7 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Herpes_US9 PF06072.6 EMC77200.1 - 0.32 10.8 1.4 0.48 10.2 1.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ADAM_spacer1 PF05986.9 EMC77201.1 - 1.1e-29 102.6 0.0 2.4e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 EMC77201.1 - 6.4e-23 80.6 94.1 1.9e-08 34.2 7.9 7.7 7 1 0 7 7 7 5 Thrombospondin type 1 domain Reprolysin PF01421.14 EMC77201.1 - 1e-22 80.6 1.7 1e-22 80.6 1.2 3.4 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EMC77201.1 - 2.8e-22 78.8 0.0 5.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 EMC77201.1 - 1.1e-12 48.3 0.6 2.8e-12 47.0 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC77201.1 - 5.3e-10 39.8 0.0 1.4e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC77201.1 - 5.4e-10 39.1 0.1 1.6e-09 37.5 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 EMC77201.1 - 6.7e-09 35.8 9.2 6.7e-09 35.8 6.4 3.3 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Reprolysin_2 PF13574.1 EMC77201.1 - 4.6e-08 33.3 0.2 1.3e-07 31.8 0.2 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC77201.1 - 0.00032 20.4 0.4 0.00057 19.6 0.3 1.3 1 0 0 1 1 1 1 Matrixin AMP-binding PF00501.23 EMC77202.1 - 2.1e-72 243.8 0.0 2.7e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC77202.1 - 0.0014 19.5 0.0 0.003 18.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AA_permease PF00324.16 EMC77203.1 - 1.6e-150 501.6 39.4 1.9e-150 501.3 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMC77203.1 - 8.2e-22 77.3 44.7 1.3e-21 76.7 31.0 1.2 1 0 0 1 1 1 1 Amino acid permease Laminin_EGF PF00053.19 EMC77204.1 - 1.1e-45 153.2 326.3 0.00052 19.8 14.0 18.8 6 4 12 18 18 18 15 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EMC77204.1 - 1.2e-12 47.0 319.7 0.0014 18.5 3.6 33.3 35 0 0 35 35 34 19 Human growth factor-like EGF EGF_2 PF07974.8 EMC77204.1 - 1.9e-08 34.2 384.6 0.0016 18.5 12.9 25.2 20 9 6 26 26 26 13 EGF-like domain EGF PF00008.22 EMC77204.1 - 0.0071 16.2 13.4 0.0071 16.2 9.3 23.5 23 3 0 23 23 21 10 EGF-like domain Baculo_11_kDa PF06143.6 EMC77204.1 - 0.017 14.4 0.8 0.03 13.6 0.5 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family SIT PF15330.1 EMC77204.1 - 0.064 13.4 0.2 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Syndecan PF01034.15 EMC77204.1 - 0.091 12.4 0.4 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain DUF912 PF06024.7 EMC77204.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EMC77204.1 - 0.27 10.8 0.5 0.46 10.0 0.4 1.3 1 0 0 1 1 1 0 Rifin/stevor family OppC_N PF12911.2 EMC77204.1 - 0.38 10.1 0.5 0.62 9.4 0.3 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2207 PF09972.4 EMC77204.1 - 0.46 9.0 0.1 0.66 8.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF836 PF05768.9 EMC77205.1 - 7.4e-16 58.1 0.2 1.1e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EMC77205.1 - 0.0028 17.5 0.3 0.0041 17.0 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EMC77205.1 - 0.0029 17.7 0.1 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC77205.1 - 0.0073 16.3 0.1 0.024 14.6 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMC77205.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.3 1 1 0 1 1 1 0 Redoxin RINGv PF12906.2 EMC77206.1 - 5.1e-15 55.2 10.3 1.3e-14 53.8 7.1 1.8 1 0 0 1 1 1 1 RING-variant domain Baculo_IE-1 PF05290.6 EMC77206.1 - 0.016 14.9 1.0 0.026 14.2 0.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EMC77206.1 - 0.091 12.4 5.9 0.52 10.0 4.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vpu PF00558.14 EMC77206.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Vpu protein zf-Apc11 PF12861.2 EMC77206.1 - 0.83 9.5 3.9 0.4 10.5 1.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-AD PF07776.10 EMC77206.1 - 1.7 8.6 6.0 3.8 7.5 4.2 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) PHD PF00628.24 EMC77206.1 - 3.4 7.4 7.4 10 5.8 5.1 1.9 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 EMC77206.1 - 4.6 7.3 8.4 16 5.5 5.8 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMC77206.1 - 6.5 6.7 8.9 3.5 7.6 3.8 2.3 3 0 0 3 3 3 0 FANCL C-terminal domain zf-RING-like PF08746.6 EMC77206.1 - 6.7 6.8 7.3 18 5.3 5.1 1.8 1 0 0 1 1 1 0 RING-like domain zf-RING_2 PF13639.1 EMC77207.1 - 3.8e-11 42.6 9.6 6.9e-11 41.8 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC77207.1 - 4.6e-11 42.1 8.7 7.9e-11 41.4 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC77207.1 - 5.8e-10 39.0 9.9 1.1e-09 38.1 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC77207.1 - 3.6e-09 36.1 8.0 6.2e-09 35.3 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77207.1 - 1.1e-07 31.3 6.1 2e-07 30.6 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC77207.1 - 0.00026 21.0 9.1 0.00065 19.7 6.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC77207.1 - 0.0016 18.2 10.9 0.003 17.4 7.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC77207.1 - 0.0034 17.0 6.7 0.0074 15.9 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EMC77207.1 - 0.014 15.1 3.9 0.022 14.4 2.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 EMC77207.1 - 0.023 14.5 5.1 0.046 13.5 3.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EMC77207.1 - 0.24 11.1 2.9 0.48 10.2 2.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EMC77207.1 - 0.41 10.2 11.3 3.8 7.1 7.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EMC77207.1 - 5.7 6.5 9.2 14 5.3 2.4 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FdhE PF04216.7 EMC77207.1 - 6.2 6.4 8.9 2.2 7.9 3.9 1.7 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation RNA_GG_bind PF10258.4 EMC77208.1 - 4e-31 106.5 3.0 6.8e-31 105.8 0.3 2.6 3 0 0 3 3 3 1 PHAX RNA-binding domain FoP_duplication PF13865.1 EMC77208.1 - 0.016 15.6 5.9 0.016 15.6 4.1 2.3 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Cmyb_C PF09316.5 EMC77208.1 - 0.026 14.1 0.3 0.026 14.1 0.2 2.1 2 0 0 2 2 2 0 C-myb, C-terminal zf-C2H2 PF00096.21 EMC77209.1 - 1.3e-15 56.7 21.3 2.2e-05 24.5 2.1 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77209.1 - 2.3e-12 46.3 18.5 0.00043 20.4 1.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC77209.1 - 1.3e-11 44.2 25.1 1.3e-06 28.4 2.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 EMC77209.1 - 0.038 14.2 4.9 1.1 9.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 EMC77209.1 - 0.19 11.2 3.2 0.44 10.0 2.2 1.6 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2_jaz PF12171.3 EMC77209.1 - 0.46 10.6 5.3 2.2 8.5 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EMC77209.1 - 2.1 8.7 6.8 0.98 9.8 0.7 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger XPC-binding PF09280.6 EMC77210.1 - 4.5e-26 90.0 17.4 7.5e-26 89.3 12.1 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EMC77210.1 - 1.1e-21 75.9 0.5 9.8e-12 44.3 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EMC77210.1 - 3e-15 55.3 0.1 5.5e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.5 EMC77210.1 - 0.00035 20.1 0.0 0.0088 15.6 0.0 2.3 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EMC77210.1 - 0.0017 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 EMC77210.1 - 0.015 15.2 0.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2407 PF10302.4 EMC77210.1 - 0.024 14.8 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Pkinase PF00069.20 EMC77212.1 - 5e-52 176.6 0.0 5.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77212.1 - 4.4e-49 166.8 0.0 5.5e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC77212.1 - 0.045 13.4 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC77212.1 - 0.058 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like dsrm PF00035.20 EMC77217.1 - 1.1e-36 125.2 0.3 6.1e-15 55.5 0.0 3.2 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EMC77217.1 - 5.5e-13 49.0 2.9 1.3e-05 25.4 0.1 4.0 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Phage_portal PF04860.7 EMC77217.1 - 0.14 10.7 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein bZIP_1 PF00170.16 EMC77219.1 - 1.6e-12 47.1 8.0 2.4e-12 46.5 5.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC77219.1 - 4.8e-10 39.0 7.8 8.6e-10 38.2 5.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC77219.1 - 6.4e-05 23.1 6.9 0.00011 22.4 4.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Microtub_assoc PF07989.6 EMC77219.1 - 0.11 12.3 1.3 0.19 11.6 0.9 1.3 1 0 0 1 1 1 0 Microtubule associated ATP-synt_C PF00137.16 EMC77221.1 - 2.7e-09 36.8 0.6 2.7e-09 36.8 0.4 1.4 2 0 0 2 2 2 1 ATP synthase subunit C Homeobox PF00046.24 EMC77223.1 - 6.3e-19 67.3 7.6 7.8e-19 67.0 5.2 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77223.1 - 0.0002 20.9 2.2 0.00037 20.1 1.5 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC77223.1 - 0.0043 16.0 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 EMC77224.1 - 1.6e-18 66.0 6.7 1.6e-18 66.0 4.7 1.7 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 EMC77224.1 - 0.0052 15.8 0.2 0.011 14.7 0.1 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC77224.1 - 0.59 9.8 4.1 0.51 10.0 1.4 2.0 2 0 0 2 2 2 0 Homeobox KN domain DUF3528 PF12045.3 EMC77225.1 - 5.5e-55 185.4 2.1 1e-54 184.5 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.24 EMC77225.1 - 6.3e-20 70.5 8.1 1.2e-19 69.6 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Baculo_p74_N PF08404.5 EMC77225.1 - 0.015 14.0 0.3 0.023 13.4 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Homeobox_KN PF05920.6 EMC77225.1 - 0.1 12.3 0.3 0.24 11.1 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 EMC77226.1 - 1.4e-21 75.8 5.9 3.4e-21 74.6 4.1 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77226.1 - 0.067 12.9 0.4 0.067 12.9 0.3 2.8 3 0 0 3 3 3 0 Homeobox KN domain Vfa1 PF08432.5 EMC77226.1 - 0.5 10.3 11.0 1.2 9.1 7.6 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hox9_act PF04617.8 EMC77227.1 - 6.8e-58 195.8 0.1 9.9e-58 195.3 0.1 1.2 1 0 0 1 1 1 1 Hox9 activation region Homeobox PF00046.24 EMC77227.1 - 2.8e-21 74.8 6.2 4.4e-21 74.2 4.3 1.3 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EMC77227.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 EMC77228.1 - 6.5e-22 76.9 4.3 6.5e-22 76.9 3.0 1.6 2 0 0 2 2 2 1 Homeobox domain DUF2380 PF09533.5 EMC77228.1 - 0.0031 16.9 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) Homeobox_KN PF05920.6 EMC77228.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Nucleoplasmin PF03066.10 EMC77228.1 - 0.086 12.3 4.4 0.12 11.9 3.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Homeobox PF00046.24 EMC77229.1 - 5.3e-22 77.1 9.7 9e-22 76.4 6.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77229.1 - 0.047 13.3 2.1 0.11 12.2 1.4 1.6 1 0 0 1 1 1 0 Homeobox KN domain Terminase_5 PF06056.7 EMC77229.1 - 0.09 12.3 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Homeobox PF00046.24 EMC77230.1 - 8.8e-23 79.6 8.1 1.5e-22 78.9 5.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77230.1 - 0.017 14.7 0.6 0.035 13.8 0.4 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.4 EMC77230.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Chromo_shadow PF01393.14 EMC77232.1 - 9e-36 121.5 0.0 1e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.19 EMC77232.1 - 0.0045 16.6 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.17 EMC77233.1 - 9.3e-31 105.2 0.5 1.5e-20 72.5 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77233.1 - 1.3e-25 89.1 0.1 3.2e-14 52.6 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC77233.1 - 3.9e-12 45.8 0.0 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 EMC77233.1 - 0.0026 17.7 0.3 0.053 13.5 0.1 2.4 2 1 0 2 2 2 1 Nmi/IFP 35 domain (NID) OB_RNB PF08206.6 EMC77233.1 - 0.0027 17.1 1.7 0.25 10.8 0.1 2.5 2 1 0 2 2 2 2 Ribonuclease B OB domain EF1G PF00647.14 EMC77234.1 - 1.1e-25 89.4 0.0 1.3e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EMC77234.1 - 5.6e-08 32.6 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC77234.1 - 1.8e-07 30.9 0.5 1.7e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC77234.1 - 9.6e-05 22.7 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.2 EMC77235.1 - 4.1e-10 39.0 12.9 0.038 13.6 0.0 6.0 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EMC77235.1 - 2.9e-08 33.3 2.8 1.4e-07 31.1 1.9 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC77235.1 - 4.4e-08 32.5 0.4 4.4e-08 32.5 0.3 2.7 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EMC77235.1 - 1.2e-07 31.3 18.2 0.0054 16.4 0.6 5.6 2 1 5 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EMC77235.1 - 8.5e-06 25.1 11.7 4.5 7.6 0.2 8.1 6 2 2 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.1 EMC77235.1 - 1.7e-05 24.4 22.2 0.25 11.5 0.0 8.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_7 PF13504.1 EMC77235.1 - 0.00036 20.2 14.2 8.2 7.1 0.0 8.3 7 1 1 8 8 8 2 Leucine rich repeat PRANC PF09372.5 EMC77235.1 - 0.038 13.9 0.2 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Adeno_E3_CR2 PF02439.10 EMC77235.1 - 0.22 11.0 0.9 0.41 10.2 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pou PF00157.12 EMC77236.1 - 3.8e-39 132.1 0.3 6.9e-39 131.3 0.2 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 EMC77236.1 - 1.8e-19 69.1 0.3 4.2e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 EMC77236.1 - 4.1e-05 23.6 0.0 0.01 16.0 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain Homeobox_KN PF05920.6 EMC77236.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain MMS22L_N PF14910.1 EMC77237.1 - 0 1161.4 20.0 0 1160.9 13.9 1.1 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal MMS22L_C PF14911.1 EMC77237.1 - 3.8e-122 407.9 3.6 8.2e-122 406.8 2.5 1.6 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal UPF0240 PF06784.6 EMC77238.1 - 4.2e-39 134.0 0.3 4.8e-39 133.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) NAP PF00956.13 EMC77238.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) 7tm_1 PF00001.16 EMC77239.1 - 3.5e-49 167.2 24.4 4.8e-49 166.8 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77239.1 - 3.9e-07 29.4 25.4 6.3e-07 28.8 17.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LIM PF00412.17 EMC77240.1 - 2.1e-48 162.2 64.2 8.8e-13 48.1 4.9 5.1 5 0 0 5 5 5 5 LIM domain DUF2042 PF09743.4 EMC77241.1 - 2.6e-105 351.6 1.6 1.1e-104 349.6 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2042) RhoGAP PF00620.22 EMC77241.1 - 0.085 12.4 2.7 2.5 7.7 0.1 2.7 1 1 0 2 2 2 0 RhoGAP domain Glyco_transf_10 PF00852.14 EMC77242.1 - 7.3e-137 455.6 3.5 8.2e-137 455.4 2.4 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) 4HBT PF03061.17 EMC77245.1 - 3.4e-14 52.7 0.1 4.3e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF92 PF01940.11 EMC77246.1 - 0.043 12.9 0.0 0.043 12.9 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF92 DED PF01335.16 EMC77247.1 - 1e-07 31.9 0.1 0.0016 18.5 0.0 2.5 1 1 1 2 2 2 2 Death effector domain ComZ PF10815.3 EMC77247.1 - 0.15 11.8 0.0 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 ComZ C1-set PF07654.10 EMC77248.1 - 3.9e-20 71.6 0.0 7.3e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.13 EMC77248.1 - 9.6e-07 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_2 PF13895.1 EMC77248.1 - 2.8e-05 24.1 0.0 5.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC77248.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC77248.1 - 0.0093 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain DSPc PF00782.15 EMC77250.1 - 1.4e-12 47.3 0.0 4.2e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC77250.1 - 4.6e-09 35.9 0.0 8.9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EMC77250.1 - 0.0006 19.2 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EMC77250.1 - 0.0038 17.4 0.0 0.061 13.5 0.1 2.6 2 0 0 2 2 2 1 Tyrosine phosphatase family 23S_rRNA_IVP PF05635.6 EMC77250.1 - 0.048 13.5 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein KRAB PF01352.22 EMC77251.1 - 1.1e-20 72.7 0.1 1.2e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 KRAB box Zds_C PF08632.5 EMC77251.1 - 0.052 12.9 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Erythro-docking PF09277.6 EMC77252.1 - 0.077 12.7 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking THRAP3_BCLAF1 PF15440.1 EMC77252.1 - 0.11 11.1 86.0 0.15 10.6 59.6 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family WW PF00397.21 EMC77253.1 - 6.3e-08 32.3 8.2 4.6e-05 23.1 4.6 3.0 3 0 0 3 3 3 2 WW domain PAT1 PF09770.4 EMC77255.1 - 0.46 8.6 7.5 0.5 8.5 5.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4505 PF14956.1 EMC77256.1 - 1.3e-55 187.9 0.0 1.4e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) LRR_4 PF12799.2 EMC77257.1 - 3.5e-08 32.8 8.2 0.0015 18.0 0.0 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC77257.1 - 0.00094 19.0 5.2 9.9 6.5 0.1 5.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 EMC77257.1 - 0.0021 17.9 11.7 10 6.8 0.1 5.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_8 PF13855.1 EMC77257.1 - 0.016 14.9 9.8 1.1 9.1 1.9 4.0 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 EMC77257.1 - 0.04 13.9 16.2 2.3 8.5 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat F5_F8_type_C PF00754.20 EMC77258.1 - 4e-13 49.3 3.1 0.00062 19.6 0.0 4.9 5 1 0 5 5 5 4 F5/8 type C domain Aminotran_1_2 PF00155.16 EMC77259.1 - 1.9e-32 112.6 0.0 2.4e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Atg8 PF02991.11 EMC77262.1 - 2.5e-45 152.6 0.4 2.8e-45 152.5 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMC77262.1 - 2.1e-06 27.8 0.0 2.6e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Telomere_Sde2 PF13019.1 EMC77262.1 - 0.078 12.6 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing Robl_LC7 PF03259.12 EMC77263.1 - 1.2e-26 92.1 0.0 1.3e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain HECT PF00632.20 EMC77264.1 - 2.4e-96 322.6 0.3 3.4e-96 322.1 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMC77264.1 - 1.3e-43 146.4 20.5 7.2e-13 48.1 0.6 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.25 EMC77264.1 - 1.9e-13 50.0 0.6 4e-13 49.0 0.4 1.6 1 0 0 1 1 1 1 C2 domain DUF605 PF04652.11 EMC77264.1 - 3 7.1 12.4 4.5 6.5 8.6 1.3 1 0 0 1 1 1 0 Vta1 like AdoHcyase PF05221.12 EMC77265.1 - 3.7e-143 475.2 0.1 4.7e-143 474.9 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EMC77265.1 - 6.9e-87 289.3 3.2 1e-86 288.8 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMC77265.1 - 1.5e-09 37.2 0.1 2.8e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EMC77265.1 - 8e-06 25.3 0.2 1.3e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EMC77265.1 - 0.00067 19.6 0.1 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EMC77265.1 - 0.0035 17.0 1.1 0.015 14.9 0.8 2.1 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EMC77265.1 - 0.015 14.9 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 EMC77265.1 - 0.021 14.9 0.2 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4448 PF14610.1 EMC77265.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Agouti PF05039.7 EMC77266.1 - 1.6e-15 57.2 11.0 2e-15 56.9 7.6 1.2 1 0 0 1 1 1 1 Agouti protein Stm1_N PF09598.5 EMC77266.1 - 0.81 10.4 4.5 1.1 9.9 3.1 1.2 1 0 0 1 1 1 0 Stm1 Toxin_9 PF02819.10 EMC77266.1 - 5.3 7.2 21.1 2.1 8.4 12.9 1.7 2 0 0 2 2 2 0 Spider toxin SRCR PF00530.13 EMC77267.1 - 1.7e-31 108.4 6.5 1.9e-21 76.2 0.3 2.1 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC77267.1 - 5e-05 23.4 1.6 0.28 11.4 0.0 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ecm29 PF13001.2 EMC77268.1 - 9e-85 285.0 0.0 6.5e-84 282.2 0.0 2.4 2 0 0 2 2 2 1 Proteasome stabiliser HEAT_2 PF13646.1 EMC77268.1 - 1.4e-18 66.9 7.1 0.0029 17.8 0.0 8.7 8 1 0 8 8 8 5 HEAT repeats HEAT PF02985.17 EMC77268.1 - 5.6e-15 54.0 13.8 0.081 13.0 0.0 11.9 14 0 0 14 14 14 4 HEAT repeat HEAT_EZ PF13513.1 EMC77268.1 - 1.3e-12 47.7 17.7 0.62 10.6 0.2 11.3 10 3 4 14 14 14 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMC77268.1 - 1.3e-11 44.7 0.0 0.0007 19.9 0.0 7.7 8 1 1 9 9 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMC77268.1 - 0.0042 16.4 12.3 0.047 13.0 0.1 5.8 6 1 0 6 6 6 1 CLASP N terminal MA3 PF02847.12 EMC77268.1 - 0.034 13.8 0.4 14 5.4 0.0 4.0 3 1 0 3 3 3 0 MA3 domain Catalase-rel PF06628.7 EMC77268.1 - 0.13 12.0 0.0 18 5.2 0.0 3.2 2 0 0 2 2 2 0 Catalase-related immune-responsive SMC_N PF02463.14 EMC77269.1 - 3.3e-27 95.1 6.9 7e-27 94.0 4.6 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC77269.1 - 4e-06 27.0 0.9 4e-06 27.0 0.6 2.2 1 1 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 EMC77269.1 - 0.0014 17.8 3.6 0.0014 17.8 2.5 1.8 2 0 0 2 2 2 1 Reovirus sigma C capsid protein FliJ PF02050.11 EMC77269.1 - 0.005 16.8 22.7 0.005 16.8 15.8 3.7 3 2 0 3 3 3 1 Flagellar FliJ protein ABC_tran PF00005.22 EMC77269.1 - 0.47 10.7 18.7 2.2e+02 2.0 12.9 3.5 1 1 0 1 1 1 0 ABC transporter PMEI PF04043.10 EMC77269.1 - 5.2 6.9 8.5 0.64 9.9 1.6 2.4 2 1 1 3 3 3 0 Plant invertase/pectin methylesterase inhibitor IFT57 PF10498.4 EMC77269.1 - 9.4 4.8 47.6 1.6 7.4 16.1 3.1 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 ADH_zinc_N PF00107.21 EMC77270.1 - 1.7e-24 85.8 0.1 2.5e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC77270.1 - 4.8e-10 40.4 0.0 1.3e-09 38.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thioredoxin PF00085.15 EMC77271.1 - 5e-31 106.4 0.7 5.4e-31 106.3 0.5 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC77271.1 - 6.6e-07 29.3 0.3 1.2e-06 28.5 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC77271.1 - 2.9e-06 27.4 0.1 3.4e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EMC77271.1 - 9.8e-05 22.0 0.2 0.00012 21.7 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EMC77271.1 - 0.0018 18.2 0.3 0.003 17.5 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EMC77271.1 - 0.0037 16.8 0.2 0.0063 16.0 0.1 1.5 1 1 1 2 2 2 1 Thioredoxin Glutaredoxin PF00462.19 EMC77271.1 - 0.0046 16.9 0.5 0.0074 16.2 0.4 1.4 1 0 0 1 1 1 1 Glutaredoxin DIM1 PF02966.11 EMC77271.1 - 0.031 13.7 0.1 0.034 13.6 0.1 1.0 1 0 0 1 1 1 0 Mitosis protein DIM1 Redoxin PF08534.5 EMC77271.1 - 0.034 13.6 0.4 0.044 13.3 0.3 1.3 1 1 0 1 1 1 0 Redoxin Sushi PF00084.15 EMC77272.1 - 0 1044.2 285.9 5.7e-13 48.9 0.7 38.4 36 2 2 38 38 36 33 Sushi domain (SCR repeat) EGF PF00008.22 EMC77272.1 - 1.4e-50 168.6 170.0 1.6e-08 34.3 5.2 15.8 12 0 0 12 12 12 10 EGF-like domain GCC2_GCC3 PF07699.8 EMC77272.1 - 2.2e-45 151.9 57.7 4.6e-13 48.5 3.4 7.6 5 0 0 5 5 5 4 GCC2 and GCC3 HYR PF02494.11 EMC77272.1 - 6.7e-38 128.5 1.1 2.7e-18 65.7 0.0 2.8 2 0 0 2 2 2 2 HYR domain Pentaxin PF00354.12 EMC77272.1 - 2.3e-29 102.2 0.0 4.3e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 EMC77272.1 - 2.1e-20 73.5 1.6 4.4e-20 72.5 1.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.8 EMC77272.1 - 5.6e-12 45.6 181.6 0.0008 19.5 5.9 15.4 12 1 0 12 12 11 8 EGF-like domain VWA PF00092.23 EMC77272.1 - 9e-12 45.0 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.10 EMC77272.1 - 9.8e-10 38.2 35.6 1.8e-07 31.0 6.2 23.2 23 2 2 25 25 19 7 Calcium-binding EGF domain EGF_3 PF12947.2 EMC77272.1 - 1.2e-07 31.5 10.2 1.2e-07 31.5 7.1 19.3 20 0 0 20 20 18 7 EGF domain Laminin_G_2 PF02210.19 EMC77272.1 - 0.00027 20.9 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.2 EMC77272.1 - 0.0024 17.8 158.2 0.0035 17.3 2.8 22.5 25 0 0 25 25 23 8 Human growth factor-like EGF VWA_2 PF13519.1 EMC77272.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Big_3_4 PF13754.1 EMC77272.1 - 0.094 13.0 0.1 0.094 13.0 0.0 6.3 10 0 0 10 10 3 0 Bacterial Ig-like domain (group 3) U79_P34 PF03064.11 EMC77272.1 - 1.6 8.1 0.0 2.8 7.3 0.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Med2 PF11214.3 EMC77272.1 - 5.5 7.0 0.0 11 6.1 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Pkinase_Tyr PF07714.12 EMC77273.1 - 1.2e-94 316.1 0.0 1.7e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.11 EMC77273.1 - 8.5e-46 153.7 0.0 1.7e-19 69.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Pkinase PF00069.20 EMC77273.1 - 1.9e-42 145.2 0.0 4.2e-42 144.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.1 EMC77273.1 - 2.8e-29 101.0 0.0 3.9e-13 49.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Kringle PF00051.13 EMC77273.1 - 6e-24 83.9 8.0 1.6e-23 82.6 5.5 1.8 1 0 0 1 1 1 1 Kringle domain Ig_3 PF13927.1 EMC77273.1 - 2.9e-22 78.9 6.3 4.1e-09 36.8 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain Fz PF01392.17 EMC77273.1 - 2.1e-20 73.2 4.3 4.6e-20 72.1 3.0 1.6 1 0 0 1 1 1 1 Fz domain ig PF00047.20 EMC77273.1 - 3.6e-19 68.6 0.2 2.9e-07 30.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC77273.1 - 2.9e-13 49.7 0.1 2.4e-05 24.2 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC77273.1 - 9.5e-11 41.4 0.1 0.0055 16.5 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC77273.1 - 1e-06 27.3 0.0 0.019 13.2 0.0 3.1 2 1 0 3 3 3 2 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EMC77273.1 - 0.01 15.3 0.5 0.021 14.3 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kinase-like PF14531.1 EMC77273.1 - 0.015 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EphA2_TM PF14575.1 EMC77273.1 - 0.03 14.6 0.1 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EMC77273.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CD34_antigen PF06365.7 EMC77273.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family 7tm_1 PF00001.16 EMC77274.1 - 7.1e-38 130.2 23.1 9.6e-38 129.7 16.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_9_N PF15420.1 EMC77274.1 - 0.099 12.3 12.4 0.055 13.2 6.3 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Epiglycanin_C PF14654.1 EMC77274.1 - 2.2 8.3 4.9 2.8 7.9 0.0 2.9 2 1 1 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region Guanylate_cyc PF00211.15 EMC77275.1 - 5.9e-65 218.0 0.2 5.6e-64 214.9 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 EMC77275.1 - 2.2e-43 148.1 0.0 3.5e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77275.1 - 3e-37 128.2 0.0 5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.9 EMC77275.1 - 2.9e-06 26.6 0.7 4.8e-06 25.9 0.5 1.4 1 0 0 1 1 1 1 Heme NO binding associated zf-C3HC4_2 PF13923.1 EMC77277.1 - 2.3e-09 37.1 8.5 2.3e-09 37.1 5.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77277.1 - 3.1e-09 36.3 7.1 3.1e-09 36.3 4.9 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77277.1 - 4.1e-09 36.1 8.2 4.1e-09 36.1 5.7 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC77277.1 - 5.4e-09 35.5 5.4 5.4e-09 35.5 3.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77277.1 - 1.3e-06 28.0 8.1 1.3e-06 28.0 5.6 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC77277.1 - 1.6e-05 24.6 7.6 1.6e-05 24.6 5.3 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EMC77277.1 - 0.00015 21.8 3.7 0.00015 21.8 2.6 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC77277.1 - 0.0027 17.4 5.7 0.01 15.5 3.9 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMC77277.1 - 0.0035 17.1 3.1 0.011 15.5 2.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EMC77277.1 - 0.15 11.9 2.1 0.37 10.5 1.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EMC77277.1 - 0.44 10.1 8.1 1.3 8.5 5.6 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RRM_1 PF00076.17 EMC77278.1 - 1.1e-66 220.3 0.1 2.5e-21 75.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77278.1 - 1.1e-38 131.0 0.0 3.2e-13 49.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC77278.1 - 5.5e-29 99.7 0.1 1.2e-11 44.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC77278.1 - 0.00054 19.7 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EMC77278.1 - 0.012 15.3 0.0 4.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 EMC77278.1 - 0.1 12.5 0.1 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif 2 Yae1_N PF09811.4 EMC77279.1 - 8e-13 47.6 49.0 1.5e+04 -10.9 34.0 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal CAAP1 PF15335.1 EMC77280.1 - 2.7e-33 113.9 10.1 4.7e-33 113.1 7.0 1.4 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 DUF2407 PF10302.4 EMC77280.1 - 0.19 11.9 2.2 2.3 8.4 1.5 2.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain LRR19-TM PF15176.1 EMC77282.1 - 2.4e-24 84.9 0.0 5.1e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.1 EMC77282.1 - 5.4e-18 64.4 24.8 1.1e-13 50.7 4.3 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC77282.1 - 6.5e-10 38.4 27.7 9.2e-05 21.9 5.1 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77282.1 - 6.9e-07 28.4 25.0 0.12 12.4 0.0 6.9 5 2 2 7 7 7 3 Leucine Rich Repeat LRR_5 PF13306.1 EMC77282.1 - 1.9e-05 24.3 8.9 1.9e-05 24.3 6.2 2.4 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC77282.1 - 0.0029 17.5 25.3 1.1 9.5 0.4 6.1 5 1 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 EMC77282.1 - 0.055 13.6 23.6 26 5.6 0.1 6.7 5 1 1 6 6 6 0 Leucine rich repeat LRR_9 PF14580.1 EMC77282.1 - 4.1 6.9 7.3 6.3 6.3 2.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeat Mob1_phocein PF03637.12 EMC77284.1 - 2.7e-81 271.4 0.3 3.1e-81 271.1 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Interferon PF00143.14 EMC77285.1 - 5.1e-37 127.2 5.1 5.8e-37 127.0 3.5 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain C9orf72-like PF15019.1 EMC77286.1 - 5.2e-85 284.3 0.0 8.2e-85 283.7 0.0 1.3 1 0 0 1 1 1 1 C9orf72-like protein family RVT_1 PF00078.22 EMC77287.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tetraspannin PF00335.15 EMC77288.1 - 9.2e-24 83.9 6.1 1e-23 83.7 4.2 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF718 PF05336.8 EMC77288.1 - 0.073 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF718) ABC2_membrane_2 PF12679.2 EMC77293.1 - 4.7 5.9 8.4 5.3 5.8 5.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MIP-T3 PF10243.4 EMC77294.1 - 0.0049 15.4 96.6 0.0077 14.7 67.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Pilt PF15453.1 EMC77294.1 - 0.11 12.1 26.7 0.23 11.1 18.5 1.5 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions AvrE PF11725.3 EMC77294.1 - 1 6.2 23.6 1.3 5.9 16.3 1.1 1 0 0 1 1 1 0 Pathogenicity factor CTF_NFI PF00859.13 EMC77295.1 - 1.1e-136 455.4 29.5 1.3e-136 455.1 20.4 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.4 EMC77295.1 - 3.8e-26 90.4 4.0 6.5e-26 89.6 2.8 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.11 EMC77295.1 - 2.3e-12 46.7 0.5 4.3e-12 45.9 0.3 1.4 1 0 0 1 1 1 1 MH1 domain UPF0104 PF03706.8 EMC77296.1 - 0.0073 15.6 1.8 0.0087 15.3 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF4446 PF14584.1 EMC77296.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) NfeD PF01957.13 EMC77296.1 - 0.03 14.4 0.2 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding 7tm_7 PF08395.7 EMC77296.1 - 0.04 12.9 0.3 0.042 12.8 0.2 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Vpu PF00558.14 EMC77296.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Vpu protein DUF4094 PF13334.1 EMC77296.1 - 0.062 13.6 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Peptidase_M56 PF05569.6 EMC77296.1 - 0.089 11.7 0.1 0.094 11.6 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 YjgP_YjgQ PF03739.9 EMC77296.1 - 0.23 10.1 2.2 0.34 9.6 1.5 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family SIT PF15330.1 EMC77296.1 - 2.6 8.2 6.1 0.15 12.1 0.5 1.8 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT HEAT_2 PF13646.1 EMC77297.1 - 3e-33 113.9 2.8 1.5e-14 53.9 0.1 3.6 1 1 3 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 EMC77297.1 - 8e-25 84.7 7.5 0.0028 17.9 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EMC77297.1 - 4.1e-08 32.6 1.2 0.22 11.6 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.18 EMC77297.1 - 9.8e-06 25.2 0.3 0.054 13.3 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EMC77297.1 - 2.1e-05 24.8 5.7 0.035 14.6 0.1 4.3 3 2 2 5 5 5 2 HEAT-like repeat MarR_2 PF12802.2 EMC77297.1 - 0.12 12.0 0.9 3.5 7.3 0.0 2.9 3 0 0 3 3 3 0 MarR family WD40 PF00400.27 EMC77298.1 - 1.1e-35 120.2 2.9 4.1e-07 29.6 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC77298.1 - 1.1e-06 28.5 0.1 0.074 12.7 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF4531 PF15041.1 EMC77299.1 - 5.2e-35 120.8 5.6 6.3e-35 120.6 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4531) HMG_box PF00505.14 EMC77300.1 - 4.5e-20 71.6 1.0 1.8e-19 69.7 0.7 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC77300.1 - 4.9e-13 49.2 0.3 1.7e-12 47.4 0.2 2.0 1 0 0 1 1 1 1 HMG-box domain OmpH PF03938.9 EMC77300.1 - 0.0058 16.5 13.6 0.086 12.7 2.6 2.2 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) IncA PF04156.9 EMC77300.1 - 0.12 11.9 15.1 0.045 13.3 3.1 2.3 2 0 0 2 2 2 0 IncA protein DUF724 PF05266.9 EMC77300.1 - 0.38 10.3 16.8 0.28 10.7 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Caudo_TAP PF02413.12 EMC77300.1 - 0.46 10.6 6.1 0.19 11.8 0.4 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein UPF0242 PF06785.6 EMC77300.1 - 0.88 8.1 12.4 0.7 8.5 4.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 EMC77300.1 - 1.7 7.6 18.4 0.88 8.5 4.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 PDZ PF00595.19 EMC77301.1 - 3.4e-08 33.5 0.0 5.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) CBM_X PF06204.6 EMC77301.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative carbohydrate binding domain 7tm_1 PF00001.16 EMC77302.1 - 1.5e-32 112.7 13.5 1.7e-32 112.5 9.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC77302.1 - 0.00034 19.8 3.3 0.00046 19.3 2.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv PIP5K PF01504.13 EMC77303.1 - 6.9e-79 264.5 0.0 9.9e-79 263.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Hemopexin PF00045.14 EMC77303.1 - 0.029 14.0 0.6 0.072 12.8 0.4 1.7 1 0 0 1 1 1 0 Hemopexin Toxin_33 PF08121.6 EMC77303.1 - 0.22 11.1 0.8 0.43 10.2 0.5 1.5 1 0 0 1 1 1 0 Waglerin family Pentapeptide_4 PF13599.1 EMC77304.1 - 0.0018 18.0 0.0 0.14 12.0 0.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) VirionAssem_T7 PF11653.3 EMC77304.1 - 0.029 15.1 5.4 9.9 7.0 0.3 3.2 1 1 2 3 3 3 0 Bacteriophage T7 virion assembly protein DUF2125 PF09898.4 EMC77304.1 - 0.54 9.5 13.7 1.3 8.2 9.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) PDZ PF00595.19 EMC77305.1 - 1.3e-44 150.2 3.5 3.6e-14 52.7 0.0 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC77305.1 - 2.4e-20 72.2 1.6 3.5e-07 30.0 0.0 3.4 3 0 0 3 3 3 3 PDZ domain SH3_2 PF07653.12 EMC77305.1 - 1.3e-10 40.6 0.0 3.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Guanylate_kin PF00625.16 EMC77305.1 - 1.6e-08 34.2 0.0 6.1e-08 32.3 0.0 1.9 1 1 1 2 2 2 1 Guanylate kinase Tricorn_PDZ PF14685.1 EMC77305.1 - 0.0001 22.0 0.5 0.98 9.2 0.0 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain SH3_1 PF00018.23 EMC77305.1 - 0.001 18.4 0.0 0.0025 17.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PID PF00640.18 EMC77306.1 - 2.6e-43 147.3 0.2 4e-43 146.7 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 EMC77306.1 - 1.1e-31 108.8 4.6 8.3e-16 57.9 0.1 2.5 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC77306.1 - 4.9e-07 29.5 0.0 0.0002 21.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain DUF993 PF06187.6 EMC77306.1 - 0.00053 18.6 0.1 0.00074 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF993) Tricorn_PDZ PF14685.1 EMC77306.1 - 0.058 13.1 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain LysM PF01476.15 EMC77306.1 - 0.072 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 LysM domain DUF1435 PF07256.7 EMC77306.1 - 0.15 12.0 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) FAD-oxidase_C PF02913.14 EMC77307.1 - 5.9e-59 199.3 0.0 8.2e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMC77307.1 - 1.9e-37 127.8 0.0 6.5e-37 126.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain bZIP_Maf PF03131.12 EMC77308.1 - 1e-16 60.9 4.1 1e-16 60.9 2.9 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EMC77308.1 - 3.3e-08 33.3 11.2 3.3e-08 33.3 7.8 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EMC77308.1 - 9.5e-06 25.3 9.6 9.5e-06 25.3 6.6 2.6 2 0 0 2 2 2 1 Basic region leucine zipper LRR_4 PF12799.2 EMC77308.1 - 0.67 9.6 4.7 0.38 10.4 0.2 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) RRM_1 PF00076.17 EMC77309.1 - 1.1e-39 133.9 0.3 3.4e-19 68.2 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77309.1 - 5.9e-35 119.0 0.1 4.5e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC77309.1 - 1.1e-17 63.5 0.1 5.4e-08 32.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC77309.1 - 0.0022 17.7 0.2 0.28 10.9 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 EMC77309.1 - 0.0025 17.8 0.1 0.009 16.0 0.1 1.9 2 0 0 2 2 2 1 Nmi/IFP 35 domain (NID) RRM_3 PF08777.6 EMC77309.1 - 0.065 13.0 1.4 0.19 11.5 0.7 1.8 2 0 0 2 2 2 0 RNA binding motif GST_C_3 PF14497.1 EMC77310.1 - 8.7e-13 48.6 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EMC77310.1 - 6.4e-07 29.3 0.5 0.007 16.2 0.0 2.7 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_2 PF13410.1 EMC77310.1 - 4.1e-06 26.5 0.0 9.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EMC77310.1 - 0.00013 22.1 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 EMC77310.1 - 0.03 14.2 0.6 0.048 13.6 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Homeobox PF00046.24 EMC77311.1 - 1.9e-22 78.5 8.8 3.6e-22 77.7 6.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77311.1 - 0.026 14.2 1.1 0.051 13.2 0.7 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 EMC77312.1 - 5.1e-22 77.2 5.4 5.6e-22 77.1 3.8 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77312.1 - 0.0016 18.1 0.1 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain MRP-63 PF14978.1 EMC77312.1 - 0.038 14.4 1.1 0.038 14.4 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 HTH_23 PF13384.1 EMC77312.1 - 0.056 13.1 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 EMC77313.1 - 1.1e-10 40.9 2.0 4.6e-10 38.9 0.2 2.2 2 0 0 2 2 2 1 Homeobox domain DUF3528 PF12045.3 EMC77314.1 - 1.7e-61 206.5 2.3 2.8e-61 205.8 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.24 EMC77314.1 - 9e-21 73.2 8.1 1.7e-20 72.4 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77314.1 - 0.075 12.7 0.3 0.22 11.2 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF1675 PF07897.6 EMC77314.1 - 1.2 8.9 6.4 0.12 12.2 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Homeobox PF00046.24 EMC77315.1 - 4.1e-19 67.9 10.6 8e-19 67.0 7.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC77315.1 - 0.0023 16.9 0.1 0.004 16.1 0.1 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC77315.1 - 0.054 13.1 0.4 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain fn2 PF00040.14 EMC77315.1 - 0.13 12.2 0.8 0.6 10.1 0.0 2.4 3 0 0 3 3 3 0 Fibronectin type II domain Homeobox PF00046.24 EMC77316.1 - 5.6e-19 67.5 6.0 6.8e-19 67.2 4.2 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77316.1 - 0.0013 18.3 2.7 0.0021 17.7 1.8 1.5 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC77316.1 - 0.035 13.1 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.1 EMC77316.1 - 0.039 13.6 0.1 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DUF2296 PF10058.4 EMC77318.1 - 8.1e-22 76.7 0.3 1.2e-21 76.1 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) 7tm_7 PF08395.7 EMC77318.1 - 0.00037 19.6 0.3 0.00048 19.2 0.2 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor TRP PF06011.7 EMC77318.1 - 0.024 13.2 0.2 0.034 12.7 0.2 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel 7tm_6 PF02949.15 EMC77318.1 - 0.059 12.2 0.2 0.085 11.7 0.1 1.3 1 0 0 1 1 1 0 7tm Odorant receptor Mito_fiss_reg PF05308.6 EMC77318.1 - 0.38 10.0 9.7 0.29 10.4 5.9 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator ATP-synt_C PF00137.16 EMC77319.1 - 1.9e-17 62.9 13.7 2.8e-17 62.3 9.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C bZIP_1 PF00170.16 EMC77320.1 - 2.9e-12 46.3 7.7 4.8e-12 45.6 5.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC77320.1 - 2.7e-10 39.9 5.3 6.2e-10 38.7 3.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC77320.1 - 0.0034 17.6 7.7 0.0087 16.3 5.3 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor ERM PF00769.14 EMC77320.1 - 0.03 13.8 4.0 0.057 12.9 2.7 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Shugoshin_N PF07558.6 EMC77320.1 - 0.032 13.9 2.3 0.15 11.7 0.3 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region zf-C2H2_4 PF13894.1 EMC77320.1 - 0.039 14.2 0.8 0.08 13.3 0.6 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC77320.1 - 0.045 14.1 1.3 0.089 13.1 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type RhoGAP PF00620.22 EMC77321.1 - 4e-50 169.3 0.0 7.3e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 EMC77321.1 - 2.1e-15 56.1 7.9 3.7e-15 55.4 5.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.19 EMC77321.1 - 9.8e-14 50.9 0.1 2.1e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 SH2 domain FYVE_2 PF02318.11 EMC77321.1 - 0.014 15.2 1.9 0.027 14.3 1.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.1 EMC77321.1 - 0.059 12.6 1.5 0.13 11.5 1.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EMC77321.1 - 0.082 12.9 5.1 0.17 11.9 3.5 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EMC77321.1 - 4.5 7.0 7.5 9 6.0 5.2 1.5 1 0 0 1 1 1 0 PHD-finger Neur_chan_LBD PF02931.18 EMC77322.1 - 6.1e-71 238.0 1.8 8e-71 237.6 1.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC77322.1 - 8.3e-63 212.4 10.5 1.7e-48 165.6 6.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF1129 PF06570.6 EMC77322.1 - 6.3 6.0 9.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Mem_trans PF03547.13 EMC77323.1 - 6e-21 74.1 30.7 3e-13 48.8 5.5 3.0 2 1 1 3 3 3 2 Membrane transport protein DEP PF00610.16 EMC77323.1 - 9.6e-13 47.6 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MMgT PF10270.4 EMC77323.1 - 0.74 10.2 6.1 1 9.7 0.2 2.8 2 0 0 2 2 2 0 Membrane magnesium transporter Cir_N PF10197.4 EMC77324.1 - 9.7e-06 25.5 5.2 9.7e-06 25.5 3.6 4.2 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR RTC_insert PF05189.8 EMC77325.1 - 0.00078 19.4 0.3 10 6.1 0.0 4.2 2 1 1 3 3 3 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4614 PF15391.1 EMC77325.1 - 0.0023 17.7 3.8 6.7 6.4 0.1 4.1 1 1 4 5 5 5 4 Domain of unknown function (DUF4614) Lamprin PF06403.6 EMC77325.1 - 2.4 7.8 8.5 27 4.5 0.1 4.1 1 1 3 4 4 4 0 Lamprin Pkinase PF00069.20 EMC77326.1 - 9.8e-34 116.6 1.4 1.1e-33 116.5 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77326.1 - 2.4e-14 53.0 0.1 3.2e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC77326.1 - 8.4e-05 22.4 0.1 0.089 12.5 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.11 EMC77326.1 - 0.037 14.0 0.4 0.061 13.2 0.2 1.5 1 1 1 2 2 2 0 ABC1 family YrbL-PhoP_reg PF10707.4 EMC77326.1 - 0.055 12.7 0.4 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Arrestin_C PF02752.17 EMC77327.1 - 2.8e-20 72.7 0.0 1e-19 70.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMC77327.1 - 3.8e-16 59.2 0.1 3.2e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 EMC77327.1 - 0.085 11.6 0.0 0.13 10.9 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Peptidase_C15 PF01470.12 EMC77328.1 - 3.4e-20 72.7 0.0 4.4e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase DUF976 PF06162.7 EMC77328.1 - 0.00029 20.3 0.0 0.00038 20.0 0.0 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans protein of unknown function (DUF976) Pkinase_Tyr PF07714.12 EMC77329.1 - 5.7e-97 323.8 0.0 8.5e-97 323.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 EMC77329.1 - 2.8e-59 197.9 6.0 3.1e-29 101.1 0.5 2.4 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.20 EMC77329.1 - 1.4e-42 145.6 0.0 2.2e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 EMC77329.1 - 7.4e-40 136.0 42.5 7.4e-40 136.0 29.5 2.0 2 0 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.16 EMC77329.1 - 2.7e-19 69.0 7.4 3.3e-07 30.3 0.1 4.7 4 1 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.1 EMC77329.1 - 0.00022 20.3 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Filament PF00038.16 EMC77330.1 - 1.1e-11 44.8 26.2 4.8e-08 32.8 8.6 4.3 3 1 1 4 4 4 2 Intermediate filament protein LRR_8 PF13855.1 EMC77331.1 - 1e-22 79.6 19.7 2.1e-12 46.6 0.7 4.7 2 2 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EMC77331.1 - 5.1e-21 73.8 17.5 8.2e-08 31.6 0.2 5.1 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77331.1 - 6.5e-14 49.8 22.3 0.17 11.9 0.0 9.5 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC77331.1 - 3.6e-09 35.3 26.1 0.36 11.2 0.2 9.6 9 1 1 10 10 10 5 Leucine rich repeat LRR_9 PF14580.1 EMC77331.1 - 0.0029 17.1 6.1 0.01 15.4 0.4 2.8 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 EMC77331.1 - 0.09 12.8 18.6 6.1 7.2 0.0 7.4 8 1 0 8 8 8 0 Leucine Rich repeat SRF-TF PF00319.13 EMC77332.1 - 4.4e-22 77.0 0.2 7.9e-22 76.2 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 EMC77332.1 - 7.9e-06 25.3 0.0 2.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat LysM PF01476.15 EMC77333.1 - 0.0038 17.0 0.1 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 LysM domain TSP_1 PF00090.14 EMC77334.1 - 2.1e-24 85.3 87.1 5.5e-10 39.2 7.0 7.2 6 1 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.14 EMC77334.1 - 6.9e-24 84.5 0.6 3.6e-18 65.8 0.1 2.9 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease ADAM_spacer1 PF05986.9 EMC77334.1 - 3e-15 56.0 0.0 5.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin_5 PF13688.1 EMC77334.1 - 4.1e-13 49.6 0.7 1.5e-12 47.8 0.5 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC77334.1 - 3.2e-10 40.5 0.0 7.8e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 EMC77334.1 - 3e-09 36.9 15.4 4.7e-09 36.3 8.0 3.6 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Reprolysin_2 PF13574.1 EMC77334.1 - 1.2e-08 35.2 0.7 6.4e-08 32.8 0.5 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC77334.1 - 1.6e-08 34.3 0.9 2.8e-07 30.2 0.6 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC77334.1 - 0.0019 17.9 0.1 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Transposase_24 PF03004.9 EMC77335.1 - 0.049 13.5 1.4 26 4.6 0.0 3.9 3 1 1 5 5 5 0 Plant transposase (Ptta/En/Spm family) CH PF00307.26 EMC77336.1 - 4.9e-14 52.2 0.4 1e-12 48.0 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain AAA_14 PF13173.1 EMC77336.1 - 1.1e-06 28.5 0.0 3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMC77336.1 - 2.1e-05 24.7 0.1 7e-05 23.0 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC77336.1 - 4e-05 23.7 0.2 0.00023 21.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC77336.1 - 7.5e-05 23.5 0.0 0.00023 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain CAMSAP_CH PF11971.3 EMC77336.1 - 0.00063 19.3 0.2 0.0076 15.8 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain AAA_16 PF13191.1 EMC77336.1 - 0.00088 19.3 2.5 0.0047 16.9 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain PhoH PF02562.11 EMC77336.1 - 0.0012 18.1 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.1 EMC77336.1 - 0.0013 18.9 0.0 0.0039 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMC77336.1 - 0.0017 18.4 0.0 0.0083 16.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EMC77336.1 - 0.0023 17.6 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMC77336.1 - 0.0024 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EMC77336.1 - 0.0091 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC77336.1 - 0.016 14.9 0.0 0.047 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DivIC PF04977.10 EMC77336.1 - 0.39 10.2 13.8 2.5 7.6 0.2 4.4 4 0 0 4 4 4 0 Septum formation initiator FlaC_arch PF05377.6 EMC77336.1 - 0.96 9.3 3.9 6.6 6.7 0.3 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.5 EMC77336.1 - 2 8.3 12.7 0.098 12.5 4.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ank PF00023.25 EMC77337.1 - 4e-40 133.6 11.5 3.9e-12 45.3 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 EMC77337.1 - 4e-37 126.4 11.4 1.7e-17 63.5 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC77337.1 - 5.6e-35 118.5 15.5 5.8e-10 39.0 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC77337.1 - 1.3e-31 108.3 13.2 4.2e-10 39.8 0.2 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77337.1 - 4.9e-26 88.2 9.1 5.5e-06 26.1 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Death PF00531.17 EMC77337.1 - 3e-12 46.1 0.1 6.3e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Death domain Abhydrolase_6 PF12697.2 EMC77338.1 - 4.1e-13 49.7 0.0 5.7e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC77338.1 - 8.8e-08 31.9 0.0 5.9e-07 29.2 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC77338.1 - 3e-07 30.2 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMC77338.1 - 0.0036 15.8 0.0 0.0052 15.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 EMC77338.1 - 0.0037 17.5 0.1 0.0086 16.3 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain AAA_2 PF07724.9 EMC77339.1 - 7.3e-42 143.1 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMC77339.1 - 1.2e-15 57.2 0.0 2.7e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EMC77339.1 - 7.3e-14 52.0 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC77339.1 - 9.5e-06 25.3 0.0 2.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMC77339.1 - 2e-05 24.1 0.0 0.00016 21.1 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 EMC77339.1 - 4.7e-05 23.4 0.0 8.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC77339.1 - 7.8e-05 22.8 0.2 0.00038 20.6 0.1 2.1 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EMC77339.1 - 8.5e-05 21.8 0.0 0.0088 15.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMC77339.1 - 0.0005 20.8 0.0 0.0013 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC77339.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMC77339.1 - 0.0013 18.1 0.0 0.004 16.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EMC77339.1 - 0.0035 17.3 0.0 0.01 15.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain T2SE PF00437.15 EMC77339.1 - 0.0038 16.1 0.0 0.0066 15.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.7 EMC77339.1 - 0.011 14.7 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EMC77339.1 - 0.012 15.2 0.3 0.049 13.2 0.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 EMC77339.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC77339.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMC77339.1 - 0.019 14.7 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EMC77339.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC77339.1 - 0.051 13.8 0.1 0.14 12.4 0.0 1.8 2 0 0 2 2 1 0 ABC transporter DEAD PF00270.24 EMC77339.1 - 0.055 12.9 0.2 0.32 10.4 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase UPF0079 PF02367.12 EMC77339.1 - 0.073 12.7 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EMC77339.1 - 0.075 12.8 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 EMC77339.1 - 0.081 11.6 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 EMC77339.1 - 0.093 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EMC77339.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EMC77339.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EMC77339.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC77339.1 - 0.13 12.4 0.0 0.64 10.2 0.0 2.2 3 0 0 3 3 1 0 RNA helicase TrwB_AAD_bind PF10412.4 EMC77339.1 - 0.18 10.4 0.0 1.3 7.5 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain zinc_ribbon_4 PF13717.1 EMC77339.1 - 0.39 10.4 5.2 6.5 6.5 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EMC77339.1 - 1.5 8.6 4.6 2.9 7.7 3.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMC77339.1 - 1.8 8.2 8.9 7.1 6.2 0.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain MutS_III PF05192.13 EMC77340.1 - 0.2 11.4 4.0 0.24 11.1 2.8 1.2 1 0 0 1 1 1 0 MutS domain III UBA PF00627.26 EMC77342.1 - 2.2e-06 27.2 1.8 0.017 14.9 0.1 2.2 2 0 0 2 2 2 2 UBA/TS-N domain Sigma54_CBD PF04963.8 EMC77342.1 - 0.0003 20.2 0.3 0.00036 20.0 0.2 1.0 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain UBA_3 PF09288.5 EMC77342.1 - 0.036 13.6 1.6 0.9 9.1 0.7 2.5 2 1 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_2 PF08587.6 EMC77342.1 - 0.063 13.4 0.1 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Kelch_1 PF01344.20 EMC77343.1 - 6.4e-19 67.2 13.7 1.3e-08 34.2 0.0 5.8 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EMC77343.1 - 3e-16 58.8 4.2 1.6e-05 24.8 0.0 5.2 4 2 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EMC77343.1 - 3.8e-12 45.7 3.4 1.4e-05 24.7 0.0 5.4 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC77343.1 - 7.1e-11 41.4 1.7 0.0015 18.1 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EMC77343.1 - 2e-07 30.9 0.7 0.045 13.9 0.0 4.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC77343.1 - 0.00029 20.7 4.9 2.2 8.3 0.1 3.9 3 1 0 3 3 3 2 Kelch motif DUF1668 PF07893.8 EMC77343.1 - 0.0074 15.4 0.3 0.6 9.1 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1668) OSTbeta PF15048.1 EMC77344.1 - 1.4e-31 109.1 0.0 1.9e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein GP41 PF00517.12 EMC77344.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Tad PF13400.1 EMC77344.1 - 0.036 14.1 0.1 0.08 12.9 0.1 1.6 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like OAD_gamma PF04277.8 EMC77344.1 - 0.071 13.5 0.5 0.15 12.4 0.4 1.6 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2474 PF10617.4 EMC77344.1 - 0.33 10.5 2.9 0.6 9.7 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2474) Formyl_trans_N PF00551.14 EMC77345.1 - 8.6e-28 97.1 0.0 1.5e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EMC77345.1 - 2.2e-10 40.5 0.2 5.1e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain DUF4480 PF13715.1 EMC77346.1 - 3.2e-13 49.5 0.0 5.6e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4480) CarboxypepD_reg PF13620.1 EMC77346.1 - 2.4e-11 43.4 0.5 1.5e-08 34.5 0.0 3.1 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain Ig_2 PF13895.1 EMC77346.1 - 2.5e-11 43.5 0.0 7.4e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC77346.1 - 2.3e-08 33.7 0.0 6.5e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain TSP_1 PF00090.14 EMC77346.1 - 4.4e-06 26.7 10.1 4.4e-06 26.7 7.0 2.8 3 0 0 3 3 3 1 Thrombospondin type 1 domain Ig_3 PF13927.1 EMC77346.1 - 6.6e-06 26.5 0.1 4.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 EMC77346.1 - 0.00045 20.2 0.0 0.0017 18.4 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC77346.1 - 0.005 16.7 0.4 0.044 13.6 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin V-set domain 7tm_1 PF00001.16 EMC77347.1 - 6.4e-53 179.5 10.7 8.4e-53 179.1 7.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77347.1 - 3.7e-07 29.5 6.5 4.9e-07 29.1 4.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PARP PF00644.15 EMC77348.1 - 3.3e-35 121.4 0.1 4.4e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain I-set PF07679.11 EMC77349.1 - 8.8e-60 198.5 0.0 1.2e-21 76.3 0.0 4.9 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC77349.1 - 7.1e-37 125.3 0.0 4.1e-08 33.2 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 EMC77349.1 - 1.7e-26 92.4 0.1 1.1e-06 28.9 0.1 5.7 5 1 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.16 EMC77349.1 - 2.3e-22 78.8 6.3 2e-13 50.2 0.4 3.0 3 0 0 3 3 3 2 Fibronectin type III domain ig PF00047.20 EMC77349.1 - 1.7e-20 72.8 0.3 3.3e-06 27.1 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 EMC77349.1 - 2.4e-19 69.3 2.1 9.7e-06 25.4 0.0 5.8 5 3 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC77349.1 - 3.3e-14 52.5 0.2 1.8e-06 27.7 0.1 4.8 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC77349.1 - 6.6e-07 29.2 0.4 0.032 14.2 0.0 4.1 5 1 0 5 5 4 2 Immunoglobulin C1-set domain C2-set PF05790.10 EMC77349.1 - 0.0022 17.8 0.0 34 4.5 0.0 4.3 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Interfer-bind PF09294.5 EMC77349.1 - 0.0092 15.9 0.4 0.032 14.2 0.3 1.9 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Adeno_E3_CR2 PF02439.10 EMC77349.1 - 0.26 10.8 4.1 0.64 9.6 2.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DPPIV_N PF00930.16 EMC77350.1 - 1.1e-97 326.8 0.0 1.4e-97 326.4 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMC77350.1 - 1.1e-59 201.2 0.0 1.8e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMC77350.1 - 1.8e-08 34.1 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EMC77350.1 - 4.8e-08 32.8 0.0 1.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC77350.1 - 0.00019 21.4 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC77350.1 - 0.026 13.9 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EMC77350.1 - 0.068 12.5 0.1 0.28 10.5 0.1 1.9 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 EMC77350.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EMC77350.1 - 0.13 11.5 0.1 0.88 8.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Na_Ca_ex PF01699.19 EMC77351.1 - 2.8e-57 192.2 42.9 2.6e-31 108.0 7.8 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cwf_Cwc_15 PF04889.7 EMC77351.1 - 0.064 12.9 16.6 0.12 12.0 11.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM177 PF14774.1 EMC77351.1 - 0.4 10.6 3.1 0.88 9.5 2.2 1.5 1 0 0 1 1 1 0 FAM177 family FAM60A PF15396.1 EMC77351.1 - 0.62 9.7 2.9 1.5 8.4 2.0 1.6 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.6 EMC77351.1 - 0.67 9.4 12.7 1 8.8 8.8 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 EMC77351.1 - 1.1 7.1 13.2 1.5 6.6 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 EMC77351.1 - 1.2 9.5 10.9 0.044 14.0 2.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BUD22 PF09073.5 EMC77351.1 - 1.9 7.4 17.1 3 6.8 11.8 1.2 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.5 EMC77351.1 - 3.2 8.0 11.2 6.6 7.0 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Dicty_REP PF05086.7 EMC77351.1 - 4 5.0 4.9 5.8 4.5 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2146 PF10220.4 EMC77351.1 - 8.4 4.2 8.8 12 3.7 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DENN PF02141.16 EMC77352.1 - 8.2e-59 198.4 3.8 8.2e-59 198.4 2.6 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 EMC77352.1 - 4.1e-22 78.0 0.6 4.1e-22 78.0 0.4 1.8 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 EMC77352.1 - 3.3e-12 46.1 0.2 1.4e-11 44.1 0.1 2.2 2 0 0 2 2 2 1 uDENN domain PPR_2 PF13041.1 EMC77352.1 - 2.9e-07 30.3 0.0 1.4e-05 24.9 0.0 2.5 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 EMC77352.1 - 0.0085 16.0 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.1 EMC77352.1 - 0.014 15.6 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Ras PF00071.17 EMC77353.1 - 1.1e-62 210.2 0.1 1.2e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77353.1 - 1.1e-20 74.2 0.0 1.7e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC77353.1 - 2.1e-11 43.4 0.1 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC77353.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC77353.1 - 8.1e-07 29.2 0.1 2.6e-06 27.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EMC77353.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMC77353.1 - 0.0025 17.0 0.1 0.0056 15.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EMC77353.1 - 0.0042 16.1 0.0 0.0047 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EMC77353.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EMC77353.1 - 0.0055 15.8 0.0 0.0098 15.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EMC77353.1 - 0.013 15.4 0.3 0.041 13.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EMC77353.1 - 0.021 14.1 0.1 0.1 11.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 EMC77353.1 - 0.028 14.7 0.1 0.038 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EMC77353.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EMC77353.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Laminin_EGF PF00053.19 EMC77354.1 - 1.8e-52 175.0 298.4 0.00031 20.6 10.9 16.7 6 4 10 16 16 16 16 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EMC77354.1 - 1.7e-07 31.2 375.4 0.0027 17.8 7.2 24.8 20 9 3 23 23 23 9 EGF-like domain hEGF PF12661.2 EMC77354.1 - 0.00065 19.6 21.2 0.0058 16.6 1.4 31.5 36 0 0 36 36 36 13 Human growth factor-like EGF Rifin_STEVOR PF02009.11 EMC77354.1 - 0.0045 16.6 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family SIT PF15330.1 EMC77354.1 - 0.022 14.8 0.1 0.058 13.5 0.0 1.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT BatD PF13584.1 EMC77354.1 - 0.2 10.2 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Syndecan PF01034.15 EMC77354.1 - 0.24 11.0 0.0 0.49 10.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EMC77354.1 - 0.31 10.3 4.4 0.55 9.5 3.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.4 EMC77354.1 - 0.33 9.4 0.1 0.45 9.0 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CoatB PF10389.4 EMC77354.1 - 0.86 9.5 2.2 1.5 8.7 1.5 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B AAA_assoc PF14363.1 EMC77355.1 - 0.026 14.5 0.4 5 7.2 0.1 2.3 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA Endonuclease_NS PF01223.18 EMC77356.1 - 1.1e-29 103.5 1.1 1.3e-29 103.3 0.8 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 EMC77356.1 - 0.0022 18.0 1.1 0.0046 16.9 0.8 1.6 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease MAGE PF01454.14 EMC77356.1 - 0.031 13.6 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 MAGE family Sushi PF00084.15 EMC77358.1 - 2e-16 60.0 8.1 1.3e-09 38.2 0.8 2.4 2 0 0 2 2 2 2 Sushi domain (SCR repeat) G-patch PF01585.18 EMC77359.1 - 1.5e-12 47.0 1.3 3.8e-12 45.7 0.9 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EMC77359.1 - 7.3e-08 32.1 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC77359.1 - 0.00015 21.3 0.1 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.6 EMC77359.1 - 5.5 5.5 5.7 7.7 5.0 4.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 6PF2K PF01591.13 EMC77360.1 - 3.5e-104 346.7 0.1 5.4e-104 346.1 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMC77360.1 - 5.3e-36 124.1 0.0 1.1e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMC77360.1 - 7.6e-09 35.5 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC77360.1 - 6.3e-05 23.7 0.1 0.0003 21.5 0.0 2.2 2 2 0 2 2 2 1 AAA domain KTI12 PF08433.5 EMC77360.1 - 0.00026 20.2 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EMC77360.1 - 0.001 18.2 0.0 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin His_Phos_2 PF00328.17 EMC77360.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 EMC77361.1 - 7.4e-66 221.9 0.0 1.2e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77361.1 - 1.2e-41 142.5 0.3 9e-41 139.6 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase C1_1 PF00130.17 EMC77361.1 - 2.1e-31 107.4 23.2 2e-16 59.4 5.3 3.0 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC77361.1 - 2.1e-11 44.1 0.4 3.8e-11 43.3 0.3 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC77361.1 - 0.00035 19.6 0.0 0.0062 15.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like IDH PF03971.9 EMC77361.1 - 0.0039 15.6 0.0 0.0068 14.8 0.0 1.3 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DZR PF12773.2 EMC77361.1 - 0.043 13.6 15.5 0.088 12.6 2.4 3.0 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 EMC77361.1 - 0.046 13.4 21.4 0.14 11.8 4.5 2.8 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.6 EMC77361.1 - 0.17 11.9 21.4 0.11 12.5 5.6 3.0 2 0 0 2 2 2 0 RING-like domain PHD_2 PF13831.1 EMC77361.1 - 0.24 10.7 10.6 1.4 8.2 1.4 2.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EMC77361.1 - 0.39 10.4 16.9 0.46 10.2 3.3 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.16 EMC77361.1 - 0.99 9.3 16.4 3.8 7.4 3.2 2.6 2 0 0 2 2 2 0 FYVE zinc finger C1_2 PF03107.11 EMC77361.1 - 7.1 6.8 15.7 0.61 10.2 3.5 3.1 2 0 0 2 2 2 0 C1 domain zf-C2H2 PF00096.21 EMC77362.1 - 1.4e-17 62.9 34.8 0.00019 21.5 0.3 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC77362.1 - 1e-16 60.2 40.0 9.7e-08 31.9 1.0 6.9 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC77362.1 - 6.6e-12 44.8 28.8 0.0066 16.6 0.1 6.0 5 0 0 5 5 5 4 C2H2-type zinc finger TP1 PF02079.11 EMC77362.1 - 0.057 13.1 0.1 0.057 13.1 0.0 2.4 3 0 0 3 3 3 0 Nuclear transition protein 1 CHORD PF04968.7 EMC77362.1 - 0.89 9.8 23.9 12 6.2 0.2 4.4 2 1 2 4 4 4 0 CHORD zf-C2H2_jaz PF12171.3 EMC77362.1 - 5.7 7.2 16.5 23 5.2 0.7 5.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding TGF_beta PF00019.15 EMC77363.1 - 4.4e-32 110.4 0.8 4.9e-32 110.3 0.6 1.0 1 0 0 1 1 1 1 Transforming growth factor beta like domain SH3_9 PF14604.1 EMC77364.1 - 1.9e-16 59.3 0.9 1.5e-12 46.8 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMC77364.1 - 1.8e-14 52.9 1.7 2e-06 27.1 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC77364.1 - 2.5e-14 52.4 0.8 2.1e-13 49.4 0.2 2.4 2 0 0 2 2 2 1 SH3 domain C1_1 PF00130.17 EMC77364.1 - 9.8e-09 34.8 11.9 1.6e-08 34.1 8.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DHHC PF01529.15 EMC77364.1 - 0.038 13.3 5.7 0.073 12.4 3.9 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase PHD PF00628.24 EMC77364.1 - 0.37 10.4 8.1 0.81 9.4 5.6 1.5 1 0 0 1 1 1 0 PHD-finger B12D PF06522.6 EMC77365.1 - 8.6e-26 89.4 0.0 9.3e-26 89.3 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SHMT PF00464.14 EMC77366.1 - 6.7e-84 281.5 0.0 7.8e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Collagen PF01391.13 EMC77367.1 - 8.9e-15 53.9 37.7 4.1e-08 32.6 12.8 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MSSP PF03940.8 EMC77367.1 - 0.12 11.7 41.8 1.5e+04 -12.6 29.0 3.3 1 1 0 1 1 1 0 Male specific sperm protein NCD1 PF04904.8 EMC77368.1 - 3.3e-48 161.3 0.1 4.2e-48 161.0 0.1 1.1 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) BTB PF00651.26 EMC77369.1 - 8.8e-24 83.6 0.1 1.7e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC77369.1 - 3.4e-14 52.3 50.0 8.2e-07 29.0 3.9 9.9 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC77369.1 - 9.3e-08 31.9 75.7 0.0014 18.8 2.4 9.7 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77369.1 - 4e-05 23.6 73.0 0.063 13.6 1.7 9.9 11 0 0 11 11 11 7 C2H2-type zinc finger BolA PF01722.13 EMC77369.1 - 0.16 11.9 1.4 27 4.8 0.1 3.2 2 1 1 3 3 3 0 BolA-like protein 7tm_1 PF00001.16 EMC77370.1 - 3.5e-44 150.8 26.1 3.5e-44 150.8 18.1 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) NAC PF01849.13 EMC77371.1 - 4.7e-26 90.0 1.2 1.1e-24 85.6 0.1 2.5 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EMC77371.1 - 0.00067 19.4 0.5 0.0014 18.3 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpo13 PF12136.3 EMC77371.1 - 0.035 13.7 3.9 0.081 12.6 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain DUF2203 PF09969.4 EMC77371.1 - 4 7.6 8.2 0.9 9.7 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Casein PF00363.13 EMC77371.1 - 8 7.1 6.9 0.76 10.4 0.4 2.2 2 0 0 2 2 2 0 Casein CS PF04969.11 EMC77372.1 - 1.5e-09 38.2 0.3 2.1e-09 37.8 0.2 1.2 1 0 0 1 1 1 1 CS domain Pkinase_C PF00433.19 EMC77372.1 - 0.22 12.0 3.8 0.5 10.9 2.1 1.9 2 1 0 2 2 2 0 Protein kinase C terminal domain ATP-synt_ab PF00006.20 EMC77373.1 - 1.9e-21 76.5 0.1 2.6e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC77373.1 - 8.3e-21 74.5 0.2 1.2e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain DUF1395 PF07160.7 EMC77374.1 - 1.2e-73 247.6 9.3 1.4e-73 247.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) GAT PF03127.9 EMC77374.1 - 0.0016 18.3 2.4 0.0016 18.3 1.6 1.9 2 0 0 2 2 2 1 GAT domain SlyX PF04102.7 EMC77374.1 - 0.026 14.8 8.2 0.094 13.0 3.9 2.7 2 0 0 2 2 2 0 SlyX DUF3161 PF11362.3 EMC77374.1 - 0.031 14.1 0.0 0.12 12.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3161) ADIP PF11559.3 EMC77374.1 - 0.041 13.7 6.6 0.089 12.6 4.6 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Peptidase_C12 PF01088.16 EMC77374.1 - 0.045 12.9 0.7 0.08 12.1 0.5 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Orbi_VP5 PF00901.12 EMC77374.1 - 0.12 10.5 7.0 1.5 6.9 2.7 2.1 1 1 1 2 2 2 0 Orbivirus outer capsid protein VP5 Rsc14 PF08586.5 EMC77374.1 - 0.15 12.5 1.2 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit V_ATPase_I PF01496.14 EMC77374.1 - 0.21 9.4 2.2 0.2 9.4 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RGS PF00615.14 EMC77374.1 - 0.23 11.5 3.7 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Regulator of G protein signaling domain Caps_synth_GfcC PF06251.6 EMC77374.1 - 0.23 10.5 2.0 0.41 9.7 1.4 1.4 1 0 0 1 1 1 0 Capsule biosynthesis GfcC V-SNARE PF05008.10 EMC77374.1 - 0.38 10.9 7.1 1.6 8.9 4.9 2.1 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CENP-Q PF13094.1 EMC77374.1 - 0.86 9.6 10.5 5 7.1 7.3 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF755 PF05501.6 EMC77374.1 - 2 8.4 5.5 4.2 7.4 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DASH_Dad3 PF08656.5 EMC77374.1 - 2.6 7.8 10.0 3.7 7.3 0.0 3.2 2 1 0 3 3 3 0 DASH complex subunit Dad3 Syntaxin PF00804.20 EMC77374.1 - 9.5 6.4 13.5 8.1e+02 0.2 7.0 3.3 2 2 1 3 3 3 0 Syntaxin Tetraspannin PF00335.15 EMC77375.1 - 2.1e-32 112.2 3.8 2.3e-32 112.0 2.6 1.0 1 0 0 1 1 1 1 Tetraspanin family OPT PF03169.10 EMC77375.1 - 0.0026 16.2 4.1 0.0035 15.8 2.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NfeD PF01957.13 EMC77375.1 - 0.0079 16.3 0.6 0.011 15.9 0.4 1.1 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding NnrS PF05940.7 EMC77375.1 - 0.0084 15.0 0.3 0.0092 14.9 0.2 1.1 1 0 0 1 1 1 1 NnrS protein Glucos_trans_II PF14264.1 EMC77375.1 - 0.013 14.5 3.9 0.017 14.1 2.7 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII SUR7 PF06687.7 EMC77375.1 - 0.055 13.0 7.1 0.021 14.4 3.4 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF2207 PF09972.4 EMC77375.1 - 0.2 10.1 0.6 0.24 9.9 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.1 EMC77375.1 - 0.22 11.2 5.0 0.19 11.4 2.2 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1628 PF07790.6 EMC77375.1 - 0.27 12.0 0.0 0.27 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) DUF4064 PF13273.1 EMC77375.1 - 0.76 9.9 6.0 11 6.2 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) FtsX PF02687.16 EMC77375.1 - 1 9.0 9.6 0.16 11.7 0.5 2.1 1 1 1 2 2 2 0 FtsX-like permease family DUF2976 PF11190.3 EMC77375.1 - 1.3 8.6 5.4 0.57 9.7 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) OppC_N PF12911.2 EMC77375.1 - 4.3 6.7 9.5 6.3 6.2 0.1 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C VWC PF00093.13 EMC77376.1 - 7.2e-05 22.8 30.6 0.00091 19.2 0.5 3.6 3 0 0 3 3 3 3 von Willebrand factor type C domain Hist_deacetyl PF00850.14 EMC77377.1 - 1.3e-60 205.3 0.0 1.5e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Phage_head_chap PF11113.3 EMC77377.1 - 0.11 12.4 0.6 0.31 10.9 0.4 1.8 1 1 0 1 1 1 0 Head assembly gene product Big_2 PF02368.13 EMC77378.1 - 0.011 15.5 0.5 0.011 15.5 0.3 4.6 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 2) Big_3_4 PF13754.1 EMC77378.1 - 0.011 15.9 0.8 3.4 8.0 0.0 3.3 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) CHU_C PF13585.1 EMC77378.1 - 0.11 12.4 1.0 0.37 10.6 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Big_2 PF02368.13 EMC77379.1 - 1.4e-09 37.7 8.7 2.9e-07 30.2 0.0 5.4 6 1 0 6 6 6 2 Bacterial Ig-like domain (group 2) PQQ PF01011.16 EMC77379.1 - 0.045 13.3 0.1 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat Sec7 PF01369.15 EMC77380.1 - 8.1e-62 208.2 0.1 2.2e-61 206.8 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain IQ PF00612.22 EMC77380.1 - 0.21 11.3 1.1 0.68 9.7 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif Tmemb_cc2 PF10267.4 EMC77382.1 - 3.6 6.0 6.9 3.9 5.9 4.8 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein LRRNT PF01462.13 EMC77383.1 - 7.8e-08 31.5 5.7 7.8e-08 31.5 3.9 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 EMC77383.1 - 0.00013 21.6 0.0 0.0003 20.4 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRRCT PF01463.19 EMC77383.1 - 0.01 16.0 0.2 0.01 16.0 0.2 2.4 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.28 EMC77383.1 - 0.018 15.0 0.4 0.65 10.2 0.0 3.2 3 1 0 3 3 3 0 Leucine Rich Repeat Ras PF00071.17 EMC77384.1 - 1.9e-36 124.9 0.1 2.3e-36 124.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77384.1 - 8.4e-08 32.7 0.0 1.8e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC77384.1 - 1.8e-06 27.3 0.1 2.1e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC77384.1 - 0.009 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Isy1 PF06246.7 EMC77385.1 - 2.3e-93 312.2 8.2 2.6e-93 312.0 5.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF1257 PF06868.6 EMC77385.1 - 0.39 10.6 2.2 15 5.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1257) zf-CCHC PF00098.18 EMC77386.1 - 1.7e-52 172.9 62.2 5.7e-08 32.3 2.1 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EMC77386.1 - 4.6e-14 51.8 52.0 0.0017 17.9 0.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.1 EMC77386.1 - 7e-09 35.0 49.3 0.0039 16.6 1.8 6.8 4 1 3 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 EMC77386.1 - 1e-07 31.5 48.4 0.0025 17.4 0.2 7.1 2 1 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 EMC77386.1 - 0.077 12.6 47.6 0.11 12.2 0.5 7.1 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 EMC77386.1 - 0.49 9.9 0.1 0.49 9.9 0.1 7.1 3 2 4 7 7 7 0 Zinc knuckle Pkinase_Tyr PF07714.12 EMC77387.1 - 1.3e-58 198.1 0.0 1.7e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77387.1 - 2.7e-55 187.3 0.0 3.9e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.10 EMC77387.1 - 1e-29 102.0 0.4 2.5e-29 100.8 0.1 1.8 2 0 0 2 2 2 1 Raf-like Ras-binding domain C1_1 PF00130.17 EMC77387.1 - 6.8e-12 44.9 8.3 1.5e-11 43.8 5.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 EMC77387.1 - 1.5e-06 27.4 0.0 2.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.6 EMC77387.1 - 0.029 14.3 6.6 0.11 12.5 4.6 2.0 1 0 0 1 1 1 0 RING-like domain APH PF01636.18 EMC77387.1 - 0.18 11.5 0.0 0.86 9.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_3 PF07649.7 EMC77387.1 - 0.57 10.2 7.0 1.1 9.3 4.9 1.5 1 0 0 1 1 1 0 C1-like domain zf-AN1 PF01428.11 EMC77387.1 - 4.9 7.1 10.5 5.4 6.9 5.6 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-CCCH PF00642.19 EMC77388.1 - 6.6e-17 60.7 30.0 2.1e-06 27.2 1.8 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EMC77388.1 - 4.7e-06 26.3 8.9 4.7e-06 26.3 6.1 3.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EMC77388.1 - 5.2e-05 22.8 10.6 5.2e-05 22.8 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77388.1 - 0.00046 19.8 9.1 0.00046 19.8 6.3 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC77388.1 - 0.0022 17.8 10.0 0.0038 17.0 4.5 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.1 EMC77388.1 - 0.0029 17.5 31.2 0.6 10.2 3.7 5.3 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type zf-rbx1 PF12678.2 EMC77388.1 - 0.003 17.6 9.0 0.003 17.6 6.2 2.5 2 1 1 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC77388.1 - 0.0036 17.2 9.5 0.0036 17.2 6.6 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) tRNA_int_endo_N PF02778.9 EMC77389.1 - 2.6e-19 68.5 0.3 9.5e-14 50.7 0.1 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_endo PF01974.12 EMC77389.1 - 5.9e-18 64.4 0.0 1.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PPARgamma_N PF12577.3 EMC77390.1 - 3.2e-34 117.1 1.9 7.2e-34 115.9 1.3 1.7 1 0 0 1 1 1 1 PPAR gamma N-terminal region Hormone_recep PF00104.25 EMC77390.1 - 2.1e-30 105.3 1.1 4.4e-30 104.3 0.7 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC77390.1 - 1.3e-27 95.8 15.0 2.4e-27 94.9 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Synapsin_C PF02750.9 EMC77391.1 - 1.8e-129 428.8 0.7 2.5e-129 428.4 0.5 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 EMC77391.1 - 4e-46 155.4 0.2 9.1e-46 154.2 0.1 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain RimK PF08443.6 EMC77391.1 - 1.5e-06 27.8 0.0 3.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain TIMP PF00965.12 EMC77392.1 - 7.7e-60 201.5 3.3 9.1e-60 201.3 2.3 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 EMC77392.1 - 0.036 13.6 0.4 0.046 13.2 0.1 1.4 1 1 0 1 1 1 0 UNC-6/NTR/C345C module CH PF00307.26 EMC77392.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.4 1 1 0 1 1 1 0 Calponin homology (CH) domain VGLL4 PF15245.1 EMC77393.1 - 5.3e-94 314.0 2.5 5.3e-94 314.0 1.7 1.8 2 1 1 3 3 3 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.9 EMC77393.1 - 0.018 14.4 0.0 5.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family DUF3868 PF12984.2 EMC77393.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) 7tm_1 PF00001.16 EMC77396.1 - 1.4e-33 116.1 14.0 4.3e-33 114.5 9.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77396.1 - 0.00063 18.9 1.9 0.23 10.5 0.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Srg PF02118.16 EMC77396.1 - 0.0093 15.4 7.4 0.014 14.8 1.7 2.2 2 0 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srt PF10321.4 EMC77396.1 - 0.015 14.0 11.4 0.34 9.6 0.5 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srv PF10323.4 EMC77396.1 - 0.016 14.3 1.3 0.016 14.3 0.9 2.6 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.1 EMC77396.1 - 0.018 14.8 0.6 0.018 14.8 0.5 1.9 2 0 0 2 2 2 0 Olfactory receptor Dicty_CAR PF05462.6 EMC77396.1 - 0.025 13.4 6.5 0.16 10.8 0.4 2.1 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor Dispanin PF04505.7 EMC77396.1 - 8 6.0 10.5 14 5.2 1.9 3.1 3 0 0 3 3 3 0 Interferon-induced transmembrane protein 7tm_1 PF00001.16 EMC77397.1 - 4.5e-47 160.3 10.1 5.4e-47 160.0 7.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC77397.1 - 9.1e-08 31.5 2.3 6.4e-07 28.7 1.6 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 EMC77397.1 - 1.8e-07 30.5 3.8 2.9e-07 29.8 2.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.8 EMC77397.1 - 7.5e-06 25.0 0.9 0.0038 16.1 0.0 2.1 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) 7TM_GPCR_Srsx PF10320.4 EMC77397.1 - 5.4e-05 22.4 12.0 0.00049 19.3 8.3 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC77397.1 - 0.011 15.5 1.4 0.011 15.5 1.0 2.6 2 1 0 2 2 2 0 Olfactory receptor DUF2417 PF10329.4 EMC77397.1 - 0.055 12.8 0.8 0.093 12.1 0.1 1.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Git3 PF11710.3 EMC77397.1 - 0.25 10.8 7.2 0.041 13.4 2.3 1.7 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF2852 PF11014.3 EMC77397.1 - 1.1 9.2 3.8 15 5.5 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) zf-nanos PF05741.8 EMC77398.1 - 3 7.8 6.6 0.69 9.9 1.3 2.5 2 1 0 2 2 2 0 Nanos RNA binding domain MARVEL PF01284.18 EMC77400.1 - 2.2e-10 40.5 14.7 3.8e-10 39.7 10.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain RseC_MucC PF04246.7 EMC77400.1 - 0.76 9.3 4.4 0.33 10.5 1.3 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SPC12 PF06645.8 EMC77400.1 - 1.5 8.6 6.9 0.23 11.3 1.4 2.0 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GlpM PF06942.7 EMC77400.1 - 3.3 8.0 10.7 0.26 11.5 1.0 2.2 1 1 1 2 2 2 0 GlpM protein NfeD PF01957.13 EMC77400.1 - 5.7 7.0 7.1 3.1 7.9 1.2 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DLIC PF05783.6 EMC77401.1 - 1.9e-249 828.1 0.0 2.3e-249 827.8 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Miro PF08477.8 EMC77401.1 - 0.00022 21.7 0.4 0.0071 16.8 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein ABC_tran PF00005.22 EMC77401.1 - 0.00046 20.4 0.0 0.00091 19.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 EMC77401.1 - 0.0086 15.5 0.3 0.38 10.1 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMC77401.1 - 0.012 15.0 0.2 0.11 11.9 0.1 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EMC77401.1 - 0.026 13.8 0.1 5.1 6.4 0.0 2.5 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.1 EMC77401.1 - 0.03 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EMC77401.1 - 0.044 13.3 0.3 0.086 12.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EMC77401.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF4461 PF14688.1 EMC77402.1 - 4.7e-111 371.1 1.6 7e-111 370.5 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.1 EMC77402.1 - 6.2e-33 112.9 0.1 1.7e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) Laps PF10169.4 EMC77404.1 - 3.6e-37 127.4 18.7 6e-37 126.7 12.9 1.3 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.4 EMC77404.1 - 0.0008 19.3 7.9 0.0008 19.3 5.5 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2423) Bax1-I PF01027.15 EMC77405.1 - 1.1e-46 159.0 28.0 1.3e-46 158.8 19.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 EMC77405.1 - 0.33 10.6 28.0 3.3 7.3 9.5 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Transport_MerF PF11431.3 EMC77405.1 - 0.63 9.7 10.4 4.5 7.0 0.0 4.3 4 0 0 4 4 4 0 Membrane transport protein MerF AAA_30 PF13604.1 EMC77406.1 - 5.9e-24 84.7 0.0 3.9e-23 82.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EMC77406.1 - 8.2e-12 45.1 0.1 2.3e-11 43.7 0.1 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EMC77406.1 - 3.5e-10 39.8 1.2 0.0082 15.6 0.0 3.5 2 1 1 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EMC77406.1 - 2.6e-07 30.2 0.0 9.5e-07 28.4 0.0 2.0 1 1 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EMC77406.1 - 6.8e-05 22.5 2.4 0.1 12.1 0.2 2.6 2 1 1 3 3 3 2 AAA domain ABC_tran PF00005.22 EMC77406.1 - 0.00029 21.1 0.0 0.001 19.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMC77406.1 - 0.00052 19.2 0.1 0.0017 17.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 CbiA PF01656.18 EMC77406.1 - 0.0016 17.9 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EMC77406.1 - 0.0035 17.3 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC77406.1 - 0.0086 16.2 0.1 0.1 12.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EMC77406.1 - 0.01 15.7 0.0 0.068 13.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMC77406.1 - 0.026 14.2 0.0 0.085 12.5 0.0 1.9 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 EMC77406.1 - 0.034 14.4 0.1 0.034 14.4 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMC77406.1 - 0.051 13.1 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.10 EMC77406.1 - 0.068 12.1 0.7 0.34 9.9 0.2 2.2 2 1 1 3 3 3 0 Anion-transporting ATPase PDZ PF00595.19 EMC77407.1 - 1.5e-91 300.6 7.7 6.7e-14 51.8 0.0 7.2 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC77407.1 - 2.5e-37 126.6 4.0 1.7e-06 27.8 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.1 EMC77407.1 - 2.2e-14 53.0 1.0 0.028 14.2 0.0 6.4 6 0 0 6 6 6 4 Tricorn protease PDZ domain GRASP55_65 PF04495.9 EMC77407.1 - 0.00015 21.7 0.1 1.9 8.4 0.0 4.0 2 2 1 4 4 4 2 GRASP55/65 PDZ-like domain MoaE PF02391.12 EMC77407.1 - 0.0053 16.5 0.2 15 5.3 0.0 4.2 4 0 0 4 4 4 1 MoaE protein EutA PF06277.6 EMC77407.1 - 0.02 13.4 0.8 0.57 8.7 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA SPO22 PF08631.5 EMC77407.1 - 0.1 11.6 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like FTH PF01827.22 EMC77407.1 - 0.13 11.9 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 FTH domain TIP120 PF08623.5 EMC77408.1 - 8.3e-68 227.2 0.8 2.4e-65 219.2 0.4 3.7 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EMC77408.1 - 1e-21 77.0 1.3 0.0051 17.0 0.0 9.0 5 4 2 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 EMC77408.1 - 1.6e-17 63.4 6.8 0.0048 17.3 0.1 12.5 11 4 4 15 15 15 3 HEAT-like repeat HEAT PF02985.17 EMC77408.1 - 6.6e-16 56.9 10.4 0.055 13.5 0.0 11.0 12 0 0 12 12 11 4 HEAT repeat UME PF08064.8 EMC77408.1 - 2.4e-10 40.3 10.7 0.0066 16.3 0.0 6.3 7 1 1 8 8 8 3 UME (NUC010) domain CLASP_N PF12348.3 EMC77408.1 - 8.8e-09 35.0 0.1 0.12 11.7 0.0 5.3 5 1 0 5 5 5 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 EMC77408.1 - 8.3e-08 32.5 3.5 0.0078 16.5 0.1 6.7 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EMC77408.1 - 9.5e-07 28.8 9.5 0.45 10.3 0.0 6.4 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 EMC77408.1 - 2.2e-06 26.6 0.5 3.7e-05 22.6 0.6 6.7 8 1 0 8 8 8 2 RNAPII transcription regulator C-terminal DUF1981 PF09324.5 EMC77408.1 - 0.0018 17.7 2.4 2.3 7.7 0.0 5.2 5 1 1 6 6 6 1 Domain of unknown function (DUF1981) DUF3385 PF11865.3 EMC77408.1 - 0.51 10.2 7.8 0.42 10.5 0.0 4.7 6 2 1 7 7 7 0 Domain of unknown function (DUF3385) Pkinase PF00069.20 EMC77409.1 - 3.7e-60 203.2 0.0 5.2e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77409.1 - 3.1e-23 82.1 0.1 5.8e-23 81.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC77409.1 - 1.9e-06 27.7 0.0 0.0002 21.1 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC77409.1 - 0.002 17.2 0.3 0.0039 16.2 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMC77409.1 - 0.0027 17.3 2.6 0.0049 16.4 1.8 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EMC77409.1 - 0.013 14.8 1.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMC77409.1 - 0.018 14.4 2.0 0.12 11.7 1.4 2.0 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EMC77409.1 - 0.048 12.6 0.0 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like IFN-gamma PF00714.12 EMC77410.1 - 3.6e-25 88.3 0.7 4.3e-25 88.1 0.5 1.1 1 0 0 1 1 1 1 Interferon gamma TelA PF05816.6 EMC77410.1 - 0.044 12.4 2.3 0.067 11.8 1.6 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF3763 PF12592.3 EMC77410.1 - 0.083 12.5 3.3 0.96 9.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3763) Peptidase_S49_N PF08496.5 EMC77410.1 - 0.25 11.1 1.9 0.37 10.5 0.8 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF342 PF03961.8 EMC77410.1 - 0.44 8.9 3.2 0.77 8.0 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EMC77410.1 - 0.66 9.5 4.1 1.4 8.4 2.9 1.7 1 1 0 1 1 1 0 IncA protein IL10 PF00726.12 EMC77411.1 - 6.6e-09 35.2 0.0 1.1e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Interleukin 10 IL22 PF14565.1 EMC77411.1 - 4.8e-06 26.6 0.0 6.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL22 PF14565.1 EMC77412.1 - 2.7e-69 231.5 2.6 3.1e-69 231.3 1.8 1.0 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.12 EMC77412.1 - 8.1e-05 21.9 0.4 9e-05 21.8 0.3 1.1 1 0 0 1 1 1 1 Interleukin 10 MDM1 PF15501.1 EMC77413.1 - 2.3e-151 505.5 38.1 1.6e-89 301.4 15.9 2.3 1 1 1 2 2 2 2 Nuclear protein MDM1 Ras PF00071.17 EMC77414.1 - 3.7e-57 192.2 0.3 4.2e-57 192.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77414.1 - 5e-21 75.4 0.1 7.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC77414.1 - 9.4e-09 34.7 0.2 9.8e-09 34.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC77414.1 - 3.5e-06 26.5 0.3 7.6e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC77414.1 - 6.2e-05 22.9 0.0 9.8e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EMC77414.1 - 0.00044 19.0 0.0 0.00056 18.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.1 EMC77414.1 - 0.13 12.4 1.2 4.8 7.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain Nup84_Nup100 PF04121.8 EMC77415.1 - 1.2e-220 733.8 19.4 1.4e-220 733.6 13.4 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF2312 PF10073.4 EMC77415.1 - 0.013 14.8 0.0 0.16 11.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TPT PF03151.11 EMC77416.1 - 4.6e-24 84.8 11.4 4.6e-24 84.8 7.9 2.4 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EMC77416.1 - 2.5e-06 27.5 10.2 2.5e-06 27.5 7.1 2.7 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 EMC77416.1 - 0.0045 15.9 17.1 0.0069 15.3 11.9 1.3 1 0 0 1 1 1 1 UAA transporter family Cyt_c_ox_IV PF12270.3 EMC77416.1 - 1.6 8.5 9.6 4.2 7.1 0.0 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV FCH PF00611.18 EMC77417.1 - 8e-18 64.4 0.6 8e-18 64.4 0.4 3.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EMC77417.1 - 2.8e-16 58.6 0.2 5.4e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC77417.1 - 3.3e-16 58.6 0.2 7.8e-16 57.4 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC77417.1 - 1.4e-12 46.9 0.0 2.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC77417.1 - 0.0036 17.4 0.1 0.0064 16.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1359 PF07097.6 EMC77417.1 - 0.52 10.3 4.6 2.1 8.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) TPR_MLP1_2 PF07926.7 EMC77417.1 - 4 7.1 32.1 0.24 11.1 0.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Neur_chan_memb PF02932.11 EMC77417.1 - 4.8 6.9 9.1 8.5 6.1 6.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dak2 PF02734.12 EMC77417.1 - 6.2 6.4 6.9 0.95 9.1 1.1 2.0 1 1 1 2 2 2 0 DAK2 domain Tetraspannin PF00335.15 EMC77418.1 - 6.1e-47 159.7 12.3 6.9e-47 159.5 8.5 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 EMC77418.1 - 0.0051 16.5 8.1 0.15 11.7 1.3 2.6 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 EMC77418.1 - 0.006 16.1 5.5 0.082 12.4 1.2 2.2 2 0 0 2 2 2 2 SUR7/PalI family DUF3481 PF11980.3 EMC77418.1 - 0.023 14.5 8.3 0.94 9.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) NfeD PF01957.13 EMC77418.1 - 0.053 13.6 1.7 0.099 12.7 0.3 1.9 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding CbiQ PF02361.11 EMC77418.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.3 1 1 0 1 1 1 0 Cobalt transport protein Hum_adeno_E3A PF05393.6 EMC77418.1 - 0.082 12.5 3.1 0.34 10.6 0.2 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Wzy_C PF04932.10 EMC77418.1 - 2 8.1 5.8 0.85 9.3 0.7 2.2 2 1 0 2 2 2 0 O-Antigen ligase EIID-AGA PF03613.9 EMC77418.1 - 2.2 7.1 5.5 0.2 10.5 0.5 1.6 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component DUF872 PF05915.7 EMC77418.1 - 3.9 7.3 6.4 3.6 7.4 2.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) FtsX PF02687.16 EMC77418.1 - 5.1 6.8 12.4 0.26 11.0 0.7 2.9 2 1 1 3 3 3 0 FtsX-like permease family Pkinase PF00069.20 EMC77419.1 - 5.4e-14 51.9 0.0 2.2e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77419.1 - 2e-07 30.3 0.0 4.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC77419.1 - 0.004 16.9 0.1 0.009 15.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family HMG_box PF00505.14 EMC77420.1 - 9.5e-19 67.4 1.2 2.6e-18 66.0 0.8 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC77420.1 - 4.2e-13 49.4 3.5 6.7e-13 48.8 0.4 2.3 1 1 1 2 2 2 1 HMG-box domain Trans_reg_C PF00486.23 EMC77420.1 - 0.0041 17.0 0.6 1.8 8.5 0.0 3.1 2 1 1 3 3 3 1 Transcriptional regulatory protein, C terminal COG5 PF10392.4 EMC77420.1 - 0.072 13.0 3.9 0.069 13.1 1.6 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 bZIP_2 PF07716.10 EMC77420.1 - 0.67 9.8 10.7 4.3 7.2 1.7 3.2 1 1 1 2 2 2 0 Basic region leucine zipper Vac_Fusion PF02346.11 EMC77420.1 - 1 8.8 4.2 7.6 6.0 0.1 3.0 2 1 1 3 3 3 0 Chordopoxvirus fusion protein IncA PF04156.9 EMC77420.1 - 3 7.4 13.3 0.64 9.5 6.5 1.7 1 1 1 2 2 2 0 IncA protein DivIC PF04977.10 EMC77420.1 - 6.1 6.4 7.1 2.2 7.8 2.2 2.3 3 1 0 3 3 3 0 Septum formation initiator LRR_8 PF13855.1 EMC77422.1 - 1.8e-51 171.7 57.2 1.4e-12 47.1 2.3 6.3 2 1 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.1 EMC77422.1 - 9.1e-27 93.3 0.3 1e-11 44.6 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_4 PF12799.2 EMC77422.1 - 9.4e-24 82.5 35.9 8.4e-06 25.2 0.3 6.8 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77422.1 - 1.4e-16 57.9 37.8 0.36 11.0 0.2 12.2 14 0 0 14 14 11 6 Leucine Rich Repeat I-set PF07679.11 EMC77422.1 - 1.3e-14 53.8 0.0 2.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_7 PF13504.1 EMC77422.1 - 5.3e-08 31.8 38.7 2 8.9 0.3 11.6 12 0 0 12 12 11 3 Leucine rich repeat Ig_2 PF13895.1 EMC77422.1 - 3.1e-07 30.4 0.0 6.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC77422.1 - 1.6e-06 28.5 0.0 4.9e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC77422.1 - 0.0005 19.9 0.0 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 EMC77422.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain LRRNT PF01462.13 EMC77422.1 - 0.05 13.1 7.7 0.043 13.3 1.8 3.1 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 EMC77422.1 - 0.064 13.3 42.0 1.9 8.8 0.1 10.6 12 0 0 12 12 11 0 Leucine Rich repeat LRR_9 PF14580.1 EMC77422.1 - 2.4 7.6 12.8 0.75 9.3 2.2 3.3 1 1 3 4 4 4 0 Leucine-rich repeat BAR_3_WASP_bdg PF10456.4 EMC77424.1 - 8.6e-109 362.3 4.2 1.2e-108 361.8 2.9 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 EMC77424.1 - 2.9e-20 72.1 4.0 8.4e-20 70.6 0.9 2.4 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.1 EMC77424.1 - 1e-11 44.2 0.0 2.6e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC77424.1 - 4.1e-10 38.8 0.0 9.9e-10 37.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC77424.1 - 2.9e-09 36.2 0.0 8.6e-09 34.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 EMC77424.1 - 3e-05 23.3 3.9 0.0016 17.7 1.0 2.9 1 1 3 4 4 4 1 Vps5 C terminal like BAR PF03114.13 EMC77424.1 - 0.0097 15.4 1.8 0.12 11.9 0.4 2.1 2 0 0 2 2 2 1 BAR domain DUF3295 PF11702.3 EMC77424.1 - 0.043 12.8 1.1 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) XFP PF03894.10 EMC77424.1 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Y_phosphatase PF00102.22 EMC77425.1 - 2.3e-81 272.6 0.0 3.3e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.15 EMC77425.1 - 1.2e-30 106.1 0.1 2.6e-30 105.0 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EMC77425.1 - 6.9e-12 45.5 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.15 EMC77425.1 - 0.0048 16.4 0.1 0.016 14.7 0.1 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC77425.1 - 0.0056 16.9 0.0 0.0099 16.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC77425.1 - 0.085 12.9 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Glyco_hydro_38 PF01074.17 EMC77426.1 - 7e-85 284.6 0.1 1.2e-84 283.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EMC77426.1 - 3.7e-46 157.8 0.0 8.5e-46 156.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EMC77426.1 - 1.9e-29 101.6 0.1 1.1e-27 95.9 0.0 2.4 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Neil1-DNA_bind PF09292.5 EMC77427.1 - 2.9e-27 94.1 1.0 5e-27 93.4 0.3 1.8 2 0 0 2 2 2 1 Endonuclease VIII-like 1, DNA bind H2TH PF06831.9 EMC77427.1 - 6.3e-10 38.6 0.0 1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EMC77427.1 - 1.6e-09 38.1 0.0 2.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain HCaRG PF07258.9 EMC77428.1 - 5.7e-52 175.8 2.3 6.3e-52 175.6 1.6 1.0 1 0 0 1 1 1 1 HCaRG protein HTH_32 PF13565.1 EMC77429.1 - 1.4e-07 32.2 1.8 2.7e-07 31.2 0.8 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EMC77429.1 - 0.0011 19.1 1.0 0.0029 17.7 0.6 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EMC77429.1 - 0.0081 16.1 0.6 1.9 8.5 0.0 2.7 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.1 EMC77429.1 - 0.024 14.2 1.0 2.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Zona_pellucida PF00100.18 EMC77430.1 - 5.7e-50 170.2 0.0 6.7e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain DC_STAMP PF07782.8 EMC77430.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 DC-STAMP-like protein LRR_6 PF13516.1 EMC77431.1 - 8.5e-06 25.3 5.8 0.29 11.3 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 EMC77431.1 - 0.00091 18.7 5.9 0.0029 17.1 1.5 3.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMC77431.1 - 0.0014 18.4 4.8 15 6.3 0.2 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EMC77431.1 - 0.0027 17.5 4.6 11 6.4 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat F-box-like PF12937.2 EMC77431.1 - 0.011 15.4 0.5 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 EMC77431.1 - 0.088 12.5 5.1 0.11 12.2 1.5 2.5 2 1 0 3 3 3 0 Leucine rich repeat Adeno_E4_34 PF04528.8 EMC77431.1 - 0.63 9.6 3.8 0.41 10.2 0.5 2.0 1 1 1 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region UCH PF00443.24 EMC77432.1 - 1e-68 231.3 0.6 2e-68 230.4 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC77432.1 - 9.9e-28 97.4 0.3 6.5e-27 94.7 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC77432.1 - 5.5e-19 68.0 11.4 5.5e-19 68.0 7.9 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Carb_anhydrase PF00194.16 EMC77433.1 - 1.3e-71 240.5 0.0 1.5e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.17 EMC77434.1 - 3.2e-51 172.9 0.4 4e-51 172.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77434.1 - 4.4e-13 49.7 0.0 8.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC77434.1 - 9.4e-12 44.5 0.4 1.1e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC77434.1 - 9.7e-05 21.8 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC77434.1 - 0.0035 16.5 0.1 0.0042 16.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3963 PF13124.1 EMC77434.1 - 0.015 15.0 0.9 0.027 14.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Ribosomal_S27e PF01667.12 EMC77435.1 - 7.3e-31 105.4 5.0 8.9e-31 105.2 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EMC77435.1 - 0.013 15.3 2.3 0.016 15.0 1.6 1.2 1 0 0 1 1 1 0 IBR domain Beta-lactamase PF00144.19 EMC77436.1 - 1.1e-52 179.1 0.0 2.3e-28 99.2 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S11 PF00768.15 EMC77436.1 - 0.016 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF3552 PF12072.3 EMC77436.1 - 0.061 12.5 9.8 0.092 11.9 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tropomyosin PF00261.15 EMC77437.1 - 3.7e-99 330.6 88.8 2.7e-97 324.5 44.3 2.0 2 0 0 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 EMC77437.1 - 4.9e-40 136.6 88.2 3.7e-27 94.9 25.3 4.1 1 1 1 3 3 3 3 Tropomyosin like Laminin_II PF06009.7 EMC77437.1 - 2.2e-06 27.4 47.4 5.5e-05 22.9 6.5 4.2 1 1 3 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.3 EMC77437.1 - 5.5e-05 22.9 10.6 5.5e-05 22.9 7.3 6.6 1 1 6 7 7 7 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EMC77437.1 - 0.0022 17.8 79.4 0.02 14.7 24.3 2.9 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 EMC77437.1 - 0.018 14.3 55.5 0.23 10.7 15.8 3.4 1 1 1 3 3 3 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 EMC77437.1 - 0.12 10.7 58.4 0.029 12.8 22.3 2.7 1 1 2 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 EMC77437.1 - 0.16 11.0 14.1 0.32 10.1 1.5 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EMC77437.1 - 0.22 11.1 75.2 0.77 9.3 16.8 3.2 1 1 2 3 3 3 0 IncA protein ADIP PF11559.3 EMC77437.1 - 0.34 10.8 61.3 0.27 11.1 6.1 4.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EMC77437.1 - 0.59 10.0 81.4 0.14 12.1 13.5 4.7 1 1 4 5 5 4 0 Domain of unknown function (DUF4200) Laminin_I PF06008.9 EMC77437.1 - 0.66 9.2 62.9 0.14 11.4 10.2 4.1 1 1 0 2 2 2 0 Laminin Domain I EzrA PF06160.7 EMC77437.1 - 0.88 7.6 63.2 0.35 9.0 20.9 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA gpW PF02831.10 EMC77437.1 - 1 8.9 9.4 5.8 6.5 0.2 3.7 4 0 0 4 4 4 0 gpW APG6 PF04111.7 EMC77437.1 - 2.9 6.8 73.3 0.87 8.5 17.9 3.3 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF745 PF05335.8 EMC77437.1 - 2.9 7.3 57.9 4.2 6.8 4.4 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF745) Flagellin_N PF00669.15 EMC77437.1 - 4.4 7.0 25.6 0.63 9.8 0.3 4.7 1 1 5 6 6 6 0 Bacterial flagellin N-terminal helical region GAS PF13851.1 EMC77437.1 - 5.2 6.2 72.0 1.2 8.2 13.7 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 EMC77437.1 - 9.6 5.6 84.6 0.12 11.9 18.2 3.4 2 2 1 3 3 3 0 Ezrin/radixin/moesin family C2 PF00168.25 EMC77438.1 - 5.9e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Hormone_recep PF00104.25 EMC77439.1 - 9e-35 119.6 2.4 9e-35 119.6 1.6 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC77439.1 - 3.8e-33 113.5 12.8 3.8e-33 113.5 8.9 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Homeobox PF00046.24 EMC77440.1 - 1.9e-22 78.5 3.7 7.1e-22 76.7 2.5 2.1 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 EMC77440.1 - 2.2e-06 26.9 1.5 6.2e-06 25.5 1.0 1.8 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 EMC77440.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain LigA PF07746.6 EMC77440.1 - 0.076 13.0 0.2 0.26 11.3 0.1 2.0 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit HA PF03457.9 EMC77440.1 - 7.5 6.7 7.6 3.3 7.8 2.8 2.1 1 1 1 2 2 2 0 Helicase associated domain Amidase PF01425.16 EMC77441.1 - 2e-104 349.9 0.0 2.4e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF4404 PF14357.1 EMC77441.1 - 0.0085 16.4 0.6 0.029 14.7 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4404) Amidase PF01425.16 EMC77442.1 - 1e-100 337.6 0.0 1.4e-100 337.2 0.0 1.2 1 0 0 1 1 1 1 Amidase UCR_hinge PF02320.11 EMC77443.1 - 1.6e-20 72.7 8.5 1.8e-20 72.6 5.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein HrpB7 PF09486.5 EMC77443.1 - 0.0097 15.8 2.7 0.0098 15.8 1.9 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) GDNF PF02351.11 EMC77443.1 - 0.027 14.9 6.1 0.032 14.7 4.2 1.1 1 0 0 1 1 1 0 GDNF/GAS1 domain HSCB_C PF07743.8 EMC77443.1 - 0.066 13.6 0.5 0.075 13.5 0.3 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Toxin_44 PF15523.1 EMC77443.1 - 0.082 12.7 1.2 0.1 12.5 0.8 1.1 1 0 0 1 1 1 0 Putative toxin 44 SNF2_N PF00176.18 EMC77444.1 - 2e-66 223.8 0.0 3.5e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC77444.1 - 2.2e-13 49.8 0.0 4.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC77444.1 - 2.6e-09 36.7 0.0 1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EMC77444.1 - 1e-08 34.3 0.0 2.5e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.5 EMC77444.1 - 7.6e-06 25.8 0.1 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 1 Rad54 N terminal ResIII PF04851.10 EMC77444.1 - 9.1e-05 22.3 0.0 0.00038 20.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EMC77444.1 - 0.088 11.7 0.0 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) LURAP PF14854.1 EMC77446.1 - 4.2e-50 168.5 3.5 5.3e-50 168.1 2.4 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein GNT-I PF03071.10 EMC77447.1 - 5.5e-51 173.4 0.2 1.2e-50 172.3 0.1 1.4 1 1 0 1 1 1 1 GNT-I family Tetraspannin PF00335.15 EMC77448.1 - 2.1e-43 148.1 15.7 3.4e-43 147.4 10.9 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF3098 PF11297.3 EMC77448.1 - 0.63 9.8 5.8 5.4 6.8 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3098) SUR7 PF06687.7 EMC77448.1 - 3.9 6.9 17.6 0.28 10.6 7.9 2.0 1 1 1 2 2 2 0 SUR7/PalI family DUF1908 PF08926.6 EMC77449.1 - 6.7e-149 494.2 0.3 6.7e-149 494.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 EMC77449.1 - 8.5e-65 218.4 0.0 1.8e-64 217.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77449.1 - 5.2e-27 94.5 0.0 1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 EMC77449.1 - 5.3e-09 36.1 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC77449.1 - 4.1e-07 29.8 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 EMC77449.1 - 3.7e-05 22.8 0.2 0.00037 19.5 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EMC77449.1 - 0.00055 19.7 0.0 0.055 13.1 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 EMC77449.1 - 0.023 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain RIO1 PF01163.17 EMC77449.1 - 0.027 13.8 0.1 0.027 13.8 0.0 2.0 3 0 0 3 3 3 0 RIO1 family DUF3429 PF11911.3 EMC77450.1 - 6.6e-32 110.4 8.9 8.5e-32 110.0 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF3325 PF11804.3 EMC77450.1 - 0.048 13.5 1.4 0.048 13.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) SHNi-TPR PF10516.4 EMC77452.1 - 1.4e-13 49.8 4.2 6.4e-13 47.7 0.5 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 EMC77452.1 - 8.5e-11 41.3 9.8 4.7e-08 32.5 1.7 3.0 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC77452.1 - 2.6e-08 33.1 11.3 0.026 14.4 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC77452.1 - 2.6e-07 29.9 7.0 0.005 16.4 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC77452.1 - 3e-05 23.8 14.9 0.00074 19.4 2.9 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC77452.1 - 0.00078 20.0 4.0 0.0041 17.7 0.3 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC77452.1 - 0.0023 17.5 8.3 5.3 7.0 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat IL17_R_N PF15037.1 EMC77452.1 - 0.045 12.7 0.1 0.045 12.7 0.1 2.0 2 0 0 2 2 2 0 Interleukin-17 receptor extracellular region TPR_7 PF13176.1 EMC77452.1 - 0.15 11.8 2.9 15 5.6 0.2 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC77452.1 - 2.8 8.5 12.3 5.9 7.5 0.0 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 EMC77453.1 - 1.9e-60 204.0 0.0 2.2e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AhpC-TSA PF00578.16 EMC77454.1 - 6.6e-43 145.3 0.1 1.3e-42 144.3 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EMC77454.1 - 8.4e-17 61.0 0.0 1.1e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EMC77454.1 - 6.3e-15 54.5 0.1 1.1e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pkinase_Tyr PF07714.12 EMC77458.1 - 2.8e-51 174.0 0.0 3.5e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77458.1 - 1.1e-48 165.6 0.0 2.2e-48 164.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EMC77458.1 - 0.001 18.1 0.1 0.0018 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CAF1 PF04857.15 EMC77459.1 - 1.2e-36 126.3 0.0 2.5e-36 125.3 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease zf-CCCH PF00642.19 EMC77459.1 - 0.00011 21.8 0.1 0.00011 21.8 0.1 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HhH-GPD PF00730.20 EMC77460.1 - 1.1e-21 77.1 0.0 2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EMC77460.1 - 2.5e-18 65.5 0.0 5.6e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.18 EMC77460.1 - 1.6e-06 27.4 0.1 6.3e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EMC77460.1 - 0.012 15.8 5.6 0.012 15.8 3.9 2.6 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Glyoxalase_4 PF13669.1 EMC77461.1 - 3.5e-06 26.9 0.0 0.043 13.8 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMC77461.1 - 2e-05 25.1 0.0 0.0096 16.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EMC77461.1 - 0.0011 18.9 0.0 0.2 11.6 0.0 2.3 1 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FliG_C PF01706.11 EMC77461.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 FliG C-terminal domain SelP_N PF04592.9 EMC77462.1 - 3.6e-25 88.7 0.9 3.8e-25 88.6 0.6 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Ribosomal_L37e PF01907.14 EMC77462.1 - 0.14 12.0 0.2 0.86 9.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L37e SWIM PF04434.12 EMC77463.1 - 0.027 13.9 1.9 0.075 12.5 1.3 1.8 1 0 0 1 1 1 0 SWIM zinc finger URO-D PF01208.12 EMC77465.1 - 5.8e-129 429.9 0.0 6.6e-129 429.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) NTP_transferase PF00483.18 EMC77466.1 - 5.4e-18 65.2 0.0 9.2e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EMC77466.1 - 8.8e-16 58.3 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EMC77466.1 - 0.0013 18.1 10.7 2.6 7.7 0.2 4.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) IspD PF01128.14 EMC77466.1 - 0.0038 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Patched PF02460.13 EMC77467.1 - 1.7e-67 228.0 9.9 2.8e-45 154.5 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EMC77467.1 - 9.1e-49 164.8 6.4 9.1e-49 164.8 4.4 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EMC77467.1 - 0.00019 20.2 4.1 0.00019 20.2 2.9 2.4 2 0 0 2 2 2 1 MMPL family MENTAL PF10457.4 EMC77467.1 - 0.026 14.1 1.5 2.5 7.6 0.6 2.4 2 0 0 2 2 2 0 Cholesterol-capturing domain Tctex-1 PF03645.8 EMC77468.1 - 2.4e-21 75.4 0.0 2.8e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF721 PF05258.7 EMC77468.1 - 0.13 12.5 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF721) Pkinase PF00069.20 EMC77469.1 - 1.1e-67 227.9 0.0 2.1e-67 226.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 EMC77469.1 - 4.5e-38 129.0 2.6 2.1e-18 66.0 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 EMC77469.1 - 1.5e-33 116.0 0.0 2.4e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC77469.1 - 6.2e-09 35.2 0.0 1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC77469.1 - 0.074 12.7 0.2 4.8 6.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_8 PF13855.1 EMC77470.1 - 2.2e-16 59.3 10.5 5.7e-09 35.5 1.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC77470.1 - 4.5e-11 42.1 9.5 1.4e-07 30.9 0.6 3.7 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77470.1 - 1.4e-10 39.6 14.1 0.045 13.7 0.2 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC77470.1 - 4.2e-07 29.1 13.6 0.23 11.8 0.2 5.4 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 EMC77470.1 - 0.0031 17.4 10.1 33 4.9 0.0 5.7 5 1 1 6 6 6 0 Leucine Rich repeat Bestrophin PF01062.16 EMC77471.1 - 2.5e-104 348.3 4.4 2.9e-104 348.1 3.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribosomal_S8e PF01201.17 EMC77472.1 - 3.1e-44 150.3 0.4 3.5e-44 150.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Kinesin PF00225.18 EMC77473.1 - 2.2e-95 319.1 0.1 2.2e-95 319.1 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain HEAT_2 PF13646.1 EMC77474.1 - 1e-06 28.9 0.3 0.0048 17.1 0.1 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EMC77474.1 - 0.00043 20.1 4.2 0.38 10.9 0.0 4.2 4 1 1 5 5 5 2 HEAT repeat Drf_GBD PF06371.8 EMC77474.1 - 0.00044 19.6 1.7 0.0012 18.1 0.1 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain E3_UbLigase_R4 PF13764.1 EMC77474.1 - 0.011 13.6 0.0 0.015 13.2 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 OST-HTH PF12872.2 EMC77474.1 - 0.015 15.1 0.0 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 OST-HTH/LOTUS domain Arm PF00514.18 EMC77474.1 - 0.019 14.7 2.9 12 5.9 0.0 5.4 4 1 2 6 6 6 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EMC77474.1 - 0.058 11.7 0.3 0.14 10.4 0.0 1.6 2 1 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 EMC77474.1 - 9 6.9 6.4 18 5.9 0.1 4.0 3 1 2 5 5 5 0 HEAT-like repeat DUF829 PF05705.9 EMC77475.1 - 1.3e-63 214.9 0.1 1.4e-63 214.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_5 PF12695.2 EMC77475.1 - 0.0079 15.9 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family GalKase_gal_bdg PF10509.4 EMC77475.1 - 0.096 11.9 0.1 0.27 10.5 0.0 1.7 1 0 0 1 1 1 0 Galactokinase galactose-binding signature PPDFL PF15060.1 EMC77476.1 - 1.2 9.1 5.7 0.3 11.1 1.4 1.8 1 1 1 2 2 2 0 Differentiation and proliferation regulator zf-C3HC4_2 PF13923.1 EMC77477.1 - 4.2e-09 36.2 14.4 4.7e-09 36.1 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77477.1 - 2e-05 24.3 14.3 2.8e-05 23.8 7.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC77477.1 - 7.2e-05 22.3 10.6 0.00015 21.3 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77477.1 - 0.00055 19.5 10.0 0.00055 19.5 7.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77477.1 - 0.00075 19.1 8.0 0.00075 19.1 5.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Endonuclease_7 PF02945.10 EMC77477.1 - 0.0014 18.2 3.8 0.017 14.8 1.2 2.5 2 0 0 2 2 2 1 Recombination endonuclease VII DZR PF12773.2 EMC77477.1 - 0.19 11.5 4.0 1.8 8.4 1.3 2.9 2 0 0 2 2 2 0 Double zinc ribbon Pox_A_type_inc PF04508.7 EMC77477.1 - 0.22 11.3 4.8 0.2 11.5 0.6 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-Apc11 PF12861.2 EMC77477.1 - 0.32 10.8 6.0 0.069 12.9 1.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EMC77477.1 - 2.1 8.1 5.8 1.3 8.9 1.9 2.1 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EMC77477.1 - 3.9 7.4 15.5 0.72 9.7 6.3 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RNase_T PF00929.19 EMC77478.1 - 6e-38 130.6 0.0 7.3e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DMAP1 PF05499.7 EMC77480.1 - 5e-81 270.4 6.8 8.3e-81 269.7 4.7 1.3 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF498 PF04430.9 EMC77480.1 - 0.079 12.5 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Atg14 PF10186.4 EMC77480.1 - 0.18 10.7 10.5 0.43 9.4 6.5 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C2H2 PF00096.21 EMC77481.1 - 2.3e-17 62.1 21.0 7.4e-06 26.0 3.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC77481.1 - 2.6e-13 49.5 13.3 2.4e-07 30.6 3.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC77481.1 - 3.2e-13 49.0 18.8 9.4e-05 22.4 2.0 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 EMC77481.1 - 0.01 15.5 14.2 0.14 11.8 2.2 3.1 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 EMC77481.1 - 0.023 14.8 10.5 0.14 12.3 0.8 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC77481.1 - 0.024 14.8 11.2 0.44 10.8 0.7 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CTP-dep_RFKase PF01982.11 EMC77481.1 - 0.078 12.6 0.0 2.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF120 HTH_18 PF12833.2 EMC77481.1 - 0.11 12.6 0.6 6.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C2H2_2 PF12756.2 EMC77481.1 - 0.2 11.7 9.4 0.19 11.8 1.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EMC77481.1 - 0.46 10.8 7.0 0.55 10.6 0.5 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2HC_2 PF13913.1 EMC77481.1 - 0.47 10.1 4.4 2.3 7.9 0.3 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_Tnp_IS1 PF03811.8 EMC77481.1 - 0.63 9.5 6.8 0.076 12.5 1.5 1.8 2 0 0 2 2 2 0 InsA N-terminal domain zf-H2C2_5 PF13909.1 EMC77481.1 - 0.96 9.8 0.1 0.96 9.8 0.1 3.6 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.1 EMC77481.1 - 5 7.0 6.3 6.4 6.7 0.3 2.4 2 1 0 2 2 2 0 Zinc-finger SNF PF00209.13 EMC77482.1 - 2.2e-192 640.1 35.6 2.5e-192 640.0 24.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ATP-synt_C PF00137.16 EMC77483.1 - 2.1e-31 107.6 27.4 6.8e-16 57.9 5.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Diphthamide_syn PF01866.12 EMC77484.1 - 5.6e-63 213.0 0.0 6.6e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Xpo1 PF08389.7 EMC77485.1 - 4e-28 98.1 9.6 2.4e-24 85.9 0.3 4.5 4 1 0 4 4 4 3 Exportin 1-like protein IBN_N PF03810.14 EMC77485.1 - 7.2e-07 29.0 3.1 1e-06 28.5 0.3 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain TGF_beta PF00019.15 EMC77486.1 - 1.6e-16 60.4 0.4 1.9e-16 60.2 0.3 1.1 1 0 0 1 1 1 1 Transforming growth factor beta like domain Glyco_transf_29 PF00777.13 EMC77487.1 - 1.5e-64 217.7 0.0 1.9e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) JmjC PF02373.17 EMC77488.1 - 1.2e-43 147.9 0.1 3.1e-43 146.6 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EMC77488.1 - 3.7e-33 113.8 9.2 3.7e-33 113.8 6.4 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC77488.1 - 2e-15 56.6 6.1 2e-15 56.6 4.2 3.6 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EMC77488.1 - 4.3e-13 48.3 8.3 4.3e-13 48.3 5.8 3.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EMC77488.1 - 2.9e-06 26.8 5.4 2.9e-06 26.8 3.8 4.2 4 0 0 4 4 4 2 PHD-finger LBR_tudor PF09465.5 EMC77488.1 - 0.00016 21.2 0.6 0.0056 16.2 0.1 2.5 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.1 EMC77488.1 - 0.0084 15.8 0.2 0.022 14.5 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.5 EMC77488.1 - 0.029 14.1 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding 53-BP1_Tudor PF09038.5 EMC77488.1 - 0.029 14.2 0.2 2 8.2 0.0 2.4 1 1 1 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Y_phosphatase PF00102.22 EMC77489.1 - 1.2e-169 561.4 1.0 3.6e-89 298.1 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 EMC77489.1 - 6e-112 366.0 30.7 1.5e-17 63.5 0.5 8.8 8 0 0 8 8 8 8 Fibronectin type III domain I-set PF07679.11 EMC77489.1 - 9.2e-44 147.2 0.0 4e-16 58.6 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC77489.1 - 1.2e-23 83.0 0.0 7e-08 32.4 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC77489.1 - 1.2e-19 70.5 4.8 0.00055 20.3 0.0 7.0 7 0 0 7 7 7 3 Immunoglobulin domain Interfer-bind PF09294.5 EMC77489.1 - 1.6e-16 60.2 0.1 0.021 14.8 0.0 7.5 8 0 0 8 8 8 3 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.20 EMC77489.1 - 3e-11 43.2 0.0 0.016 15.3 0.0 4.7 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC77489.1 - 1.1e-08 34.9 0.1 0.025 14.4 0.0 4.7 4 1 0 4 4 3 2 Immunoglobulin V-set domain DSPc PF00782.15 EMC77489.1 - 1.8e-08 34.0 0.0 0.0034 16.9 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC77489.1 - 1.1e-07 32.2 0.0 0.068 13.4 0.0 3.3 3 0 0 3 3 3 2 Tyrosine phosphatase family C2-set_2 PF08205.7 EMC77489.1 - 4.4e-07 29.7 4.3 0.095 12.6 0.0 4.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain PTPlike_phytase PF14566.1 EMC77489.1 - 1e-06 28.8 0.1 0.0027 17.7 0.0 2.9 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_Y_Y PF07495.8 EMC77489.1 - 1.4e-06 27.9 0.8 0.017 14.8 0.0 3.6 3 0 0 3 3 3 2 Y_Y_Y domain TMEM154 PF15102.1 EMC77489.1 - 0.00076 19.2 0.0 0.00076 19.2 0.0 1.9 2 0 0 2 2 1 1 TMEM154 protein family DUF2369 PF10179.4 EMC77489.1 - 0.027 13.6 0.1 28 3.6 0.0 4.1 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) ICAM_N PF03921.9 EMC77489.1 - 0.11 11.9 0.0 0.49 9.9 0.0 2.2 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF1410 PF07198.6 EMC77489.1 - 0.14 12.4 1.0 2.9 8.2 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) YhjQ PF06564.7 EMC77489.1 - 0.29 10.4 0.0 0.6 9.4 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein AP_endonuc_2 PF01261.19 EMC77490.1 - 1.3e-16 60.5 0.0 2.3e-16 59.7 0.0 1.3 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Sigma70_r4 PF04545.11 EMC77491.1 - 0.11 11.7 0.1 5.4 6.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 Med8 PF10232.4 EMC77494.1 - 9.4e-69 231.3 1.0 1.2e-68 231.0 0.7 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Baculo_PEP_C PF04513.7 EMC77494.1 - 0.053 13.3 0.3 11 5.8 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELO PF01151.13 EMC77495.1 - 2.9e-64 216.7 22.2 3.6e-64 216.4 15.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 EMC77496.1 - 9e-36 120.4 15.3 4.5e-09 35.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC77496.1 - 8.2e-07 28.9 0.8 0.0092 15.7 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC77496.1 - 0.038 12.1 6.0 5.9 4.8 0.4 3.8 2 2 0 2 2 2 0 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 EMC77496.1 - 0.083 12.6 3.9 0.33 10.6 0.4 3.2 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term EpoR_lig-bind PF09067.5 EMC77497.1 - 1.7e-30 105.0 0.2 1.1e-27 96.0 0.1 2.8 3 0 0 3 3 3 2 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 EMC77497.1 - 3.5e-11 43.1 1.7 0.00034 20.7 0.0 2.5 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding fn3 PF00041.16 EMC77497.1 - 6.6e-11 42.1 0.2 7.4e-08 32.4 0.2 2.9 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.12 EMC77497.1 - 0.00011 21.8 0.1 0.00048 19.8 0.0 2.1 2 0 0 2 2 2 1 Tissue factor LRR_8 PF13855.1 EMC77498.1 - 1.4e-26 92.0 29.7 2.6e-12 46.2 3.7 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC77498.1 - 5.2e-15 54.6 13.6 5.4e-08 32.2 0.6 3.4 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77498.1 - 2.8e-10 38.7 16.1 0.015 15.2 0.0 5.4 5 1 0 5 5 5 5 Leucine Rich Repeat LRR_9 PF14580.1 EMC77498.1 - 9.1e-05 22.0 0.1 0.00012 21.7 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EMC77498.1 - 0.00011 21.7 18.6 1.2 9.6 0.4 5.5 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 EMC77498.1 - 0.0016 18.3 21.6 1.5 9.1 0.5 5.3 3 1 2 5 5 5 3 Leucine Rich repeat LRR_5 PF13306.1 EMC77498.1 - 0.0052 16.4 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) TMEM125 PF15109.1 EMC77499.1 - 2.8e-53 178.7 8.2 2.8e-53 178.7 5.7 1.9 2 0 0 2 2 2 1 TMEM125 protein family Claudin_2 PF13903.1 EMC77499.1 - 0.057 13.0 13.2 0.25 11.0 3.9 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4234 PF14018.1 EMC77499.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Cytochrom_B_N PF00033.14 EMC77499.1 - 0.4 10.0 2.3 3.7 6.8 1.6 2.1 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB ABC2_membrane_2 PF12679.2 EMC77499.1 - 2 7.2 15.3 12 4.6 10.6 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein NfeD PF01957.13 EMC77499.1 - 2.3 8.3 11.3 3.2 7.8 2.0 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding PIRT PF15099.1 EMC77499.1 - 2.7 7.2 12.4 0.22 10.7 5.2 1.7 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family DUF4013 PF13197.1 EMC77499.1 - 2.8 7.2 16.3 0.3 10.3 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) IncA PF04156.9 EMC77499.1 - 3.5 7.1 25.8 0.8 9.2 4.4 2.2 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 EMC77500.1 - 1.3e-17 62.9 8.7 1.8e-05 24.4 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat AAA_13 PF13166.1 EMC77500.1 - 4.4e-05 22.1 29.4 4.4e-05 22.1 20.4 3.1 1 1 2 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 EMC77500.1 - 4.9e-05 22.6 9.0 0.0005 19.3 0.5 3.8 3 2 1 5 5 5 2 Reovirus sigma C capsid protein DUF3639 PF12341.3 EMC77500.1 - 0.085 12.8 0.4 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) KH_5 PF13184.1 EMC77500.1 - 0.14 11.9 3.2 0.91 9.3 0.0 3.4 2 1 0 2 2 2 0 NusA-like KH domain Ebp2 PF05890.7 EMC77501.1 - 7e-92 307.5 25.1 8.7e-92 307.2 17.4 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 AAA_11 PF13086.1 EMC77501.1 - 0.22 11.0 4.3 0.38 10.2 3.0 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EMC77501.1 - 0.37 8.5 7.2 0.48 8.2 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LTXXQ PF07813.7 EMC77501.1 - 0.53 10.7 15.4 0.14 12.6 7.8 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein GvpL_GvpF PF06386.6 EMC77501.1 - 1.1 8.8 10.9 0.12 11.9 4.5 1.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF WXG100 PF06013.7 EMC77501.1 - 2.8 8.0 9.3 1.1 9.2 0.6 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG FAM183 PF14886.1 EMC77502.1 - 3.8e-15 56.3 0.3 4e-15 56.2 0.2 1.0 1 0 0 1 1 1 1 FAM183A and FAM183B related PIF1 PF05970.9 EMC77503.1 - 3e-46 158.0 0.8 3.1e-43 148.1 0.5 3.0 2 1 0 2 2 2 1 PIF1-like helicase UvrD_C_2 PF13538.1 EMC77503.1 - 5.2e-05 23.3 0.0 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EMC77503.1 - 0.00018 19.4 0.0 0.00025 18.9 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 EMC77503.1 - 0.0011 18.6 0.0 0.0035 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Phage_CI_repr PF07022.8 EMC77503.1 - 0.15 12.1 0.0 20 5.3 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain ENOD40 PF08247.6 EMC77503.1 - 4.8 7.1 5.4 4.5 7.2 0.1 2.9 2 0 0 2 2 2 0 ENOD40 protein SOUL PF04832.7 EMC77504.1 - 1.9e-43 148.0 0.0 2.1e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein DHDPS PF00701.17 EMC77505.1 - 5.8e-47 159.6 0.0 6.6e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family QCR10 PF09796.4 EMC77505.1 - 0.21 11.2 1.6 0.86 9.3 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) dsrm PF00035.20 EMC77506.1 - 2.5e-23 82.4 0.4 2.7e-10 40.6 0.2 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 EMC77506.1 - 2.5e-14 52.8 0.0 6.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC77506.1 - 5.1e-07 29.3 0.1 1.7e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 EMC77506.1 - 1.9e-06 27.8 0.1 7.4e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) T2SE PF00437.15 EMC77506.1 - 0.0032 16.4 0.0 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EMC77506.1 - 0.007 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EMC77506.1 - 0.012 15.5 0.0 0.066 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EMC77506.1 - 0.032 13.3 0.1 0.089 11.9 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.1 EMC77506.1 - 0.054 13.0 0.1 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EMC77506.1 - 0.081 12.7 0.5 2.1 8.1 0.0 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DND1_DSRM PF14709.1 EMC77506.1 - 0.088 13.1 0.0 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 OB_NTP_bind PF07717.11 EMC77507.1 - 8e-15 54.6 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC77507.1 - 0.041 13.9 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) Laminin_N PF00055.12 EMC77508.1 - 1.3e-92 309.0 0.0 2.6e-92 308.1 0.0 1.5 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 EMC77508.1 - 1.8e-72 239.0 212.5 3.3e-11 42.9 9.4 11.2 11 1 1 12 12 12 9 Laminin EGF-like (Domains III and V) Laminin_B PF00052.13 EMC77508.1 - 1.4e-41 141.2 0.0 2.1e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF3323 PF11796.3 EMC77509.1 - 0.0075 15.6 1.1 0.0092 15.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function N-terminus (DUF3323) YscO PF07321.7 EMC77509.1 - 0.0077 16.0 2.6 0.012 15.3 1.8 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO Rab5-bind PF09311.6 EMC77509.1 - 0.021 14.6 3.2 0.18 11.6 0.6 2.1 2 0 0 2 2 2 0 Rabaptin-like protein Nup54 PF13874.1 EMC77509.1 - 0.038 13.6 3.0 0.06 13.0 2.1 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 EMC77509.1 - 0.038 13.7 0.8 0.094 12.4 0.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.5 EMC77509.1 - 0.051 13.6 1.3 0.085 12.9 0.9 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil ABC_tran_2 PF12848.2 EMC77509.1 - 0.083 12.7 0.6 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 ABC transporter CTP_transf_2 PF01467.21 EMC77511.1 - 9.7e-23 80.9 0.0 3.1e-22 79.3 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase EST1_DNA_bind PF10373.4 EMC77512.1 - 1.1e-62 211.7 5.6 2.4e-62 210.7 3.8 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EMC77512.1 - 1.2e-23 83.5 0.3 1.2e-23 83.5 0.2 2.6 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EMC77512.1 - 1e-06 28.2 0.1 2.9e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 TPR repeat zf-AD PF07776.10 EMC77512.1 - 0.0031 17.4 0.6 0.012 15.6 0.4 2.1 1 1 0 1 1 1 1 Zinc-finger associated domain (zf-AD) TPR_12 PF13424.1 EMC77512.1 - 0.028 14.3 0.2 0.068 13.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ubiquitin PF00240.18 EMC77512.1 - 0.032 13.6 0.1 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family TPR_2 PF07719.12 EMC77512.1 - 0.044 13.7 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC77512.1 - 0.071 12.9 0.0 0.28 11.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC77512.1 - 0.097 12.9 1.8 0.94 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC77512.1 - 0.15 11.9 0.6 0.52 10.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SH3_1 PF00018.23 EMC77513.1 - 4.9e-28 96.2 0.0 9.9e-16 56.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC77513.1 - 2.8e-23 81.2 0.1 3.4e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain TPR_11 PF13414.1 EMC77513.1 - 7.7e-22 76.7 6.1 2.7e-11 42.9 0.6 3.3 1 1 2 3 3 3 3 TPR repeat SH3_2 PF07653.12 EMC77513.1 - 9e-18 63.5 0.0 1.1e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain TPR_1 PF00515.23 EMC77513.1 - 4.2e-17 60.9 1.4 3.9e-06 26.2 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC77513.1 - 6.9e-16 56.8 2.7 5.8e-05 22.6 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC77513.1 - 6.4e-13 48.4 0.1 3e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC77513.1 - 4.6e-11 41.6 0.2 0.04 13.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC77513.1 - 2e-08 33.3 0.6 0.035 13.8 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.19 EMC77513.1 - 9.4e-07 28.4 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.1 EMC77513.1 - 2.5e-06 27.5 0.7 0.39 11.2 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC77513.1 - 5.2e-06 26.2 0.0 0.041 14.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC77513.1 - 2.7e-05 24.4 0.1 0.29 11.8 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC77513.1 - 0.00011 22.7 0.7 0.76 10.5 0.4 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC77513.1 - 0.00061 19.6 1.8 0.013 15.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC77513.1 - 0.024 14.5 0.1 9.9 6.2 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Cohesin_load PF10345.4 EMC77513.1 - 0.074 11.2 0.3 0.11 10.7 0.2 1.1 1 0 0 1 1 1 0 Cohesin loading factor Apc3 PF12895.2 EMC77513.1 - 0.17 12.0 2.9 1.9 8.6 1.5 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 P16-Arc PF04699.9 EMC77514.1 - 1.7e-40 138.5 0.1 1.8e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 EMC77514.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family APOBEC_N PF08210.6 EMC77515.1 - 3.6e-15 56.0 0.4 4.2e-15 55.8 0.3 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 EMC77515.1 - 0.11 12.2 1.5 0.14 11.8 1.1 1.2 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase RasGEF PF00617.14 EMC77516.1 - 8.1e-62 208.2 1.1 1.5e-61 207.4 0.8 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC77516.1 - 6.4e-19 67.9 0.0 3.3e-18 65.7 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.18 EMC77516.1 - 1.1e-15 57.9 0.1 7.1e-15 55.2 0.0 2.5 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Acyl-CoA_ox_N PF14749.1 EMC77516.1 - 0.00015 22.0 0.4 0.24 11.6 0.0 3.4 3 0 0 3 3 3 2 Acyl-coenzyme A oxidase N-terminal CS PF04969.11 EMC77517.1 - 2.1e-14 53.7 1.2 4.2e-14 52.8 0.2 1.9 2 0 0 2 2 2 1 CS domain SGS PF05002.10 EMC77517.1 - 1.5e-13 50.2 3.8 3.3e-13 49.1 2.7 1.6 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.6 EMC77517.1 - 1e-11 44.6 2.1 1e-11 44.6 1.4 2.5 2 0 0 2 2 2 1 Siah interacting protein, N terminal SRP14 PF02290.10 EMC77517.1 - 0.24 11.3 2.7 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Signal recognition particle 14kD protein DUF1366 PF07104.6 EMC77517.1 - 0.31 10.6 3.8 0.16 11.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) WD40 PF00400.27 EMC77518.1 - 1.4e-30 104.0 7.2 2.6e-06 27.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-C3HC4 PF00097.20 EMC77518.1 - 1.8e-09 37.0 8.6 5.4e-09 35.5 6.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC77518.1 - 2.7e-09 36.8 7.9 9.6e-09 35.1 5.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77518.1 - 7.4e-08 32.0 6.2 7.4e-08 32.0 4.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC77518.1 - 1.2e-07 31.2 5.2 3.4e-07 29.8 3.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77518.1 - 4.7e-07 29.4 7.3 4.7e-07 29.4 5.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC77518.1 - 2.1e-06 27.4 7.5 6.9e-06 25.8 5.2 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC77518.1 - 0.00019 21.0 3.8 0.00062 19.4 2.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMC77518.1 - 0.002 18.1 3.0 0.002 18.1 2.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EMC77518.1 - 0.0033 16.9 7.4 0.0083 15.6 5.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain AAA_23 PF13476.1 EMC77518.1 - 1.9 8.8 6.9 4.7 7.4 4.8 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M43 PF05572.8 EMC77519.1 - 2.2e-13 50.0 0.5 5.2e-13 48.8 0.3 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Sushi PF00084.15 EMC77519.1 - 8.2e-10 38.8 60.9 8.2e-07 29.2 0.7 9.2 9 0 0 9 9 9 4 Sushi domain (SCR repeat) Notch PF00066.12 EMC77519.1 - 9.7e-08 32.1 8.2 9.7e-08 32.1 5.7 4.4 3 1 0 3 3 3 1 LNR domain fn3 PF00041.16 EMC77519.1 - 0.0038 17.3 0.4 0.032 14.3 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Reprolysin_2 PF13574.1 EMC77519.1 - 0.0067 16.4 0.2 0.016 15.2 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EMC77519.1 - 0.026 13.4 0.6 0.044 12.6 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 EMC77519.1 - 0.034 14.6 0.6 0.078 13.5 0.4 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EMC77519.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 EMC77519.1 - 0.17 11.4 3.9 0.61 9.5 2.7 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC77519.1 - 0.84 9.3 1.8 1.6 8.4 1.2 1.3 1 0 0 1 1 1 0 Matrixin FXa_inhibition PF14670.1 EMC77520.1 - 2.2e-10 40.4 35.1 3e-09 36.8 2.3 4.0 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site MACPF PF01823.14 EMC77520.1 - 0.0043 16.7 0.3 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain UPF0560 PF10577.4 EMC77520.1 - 0.03 12.5 0.1 0.044 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Tme5_EGF_like PF09064.5 EMC77520.1 - 7.7 6.2 18.7 0.014 15.0 3.9 3.0 3 0 0 3 3 3 0 Thrombomodulin like fifth domain, EGF-like MACPF PF01823.14 EMC77521.1 - 3.2e-05 23.7 0.0 7.8e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 MAC/Perforin domain OGG_N PF07934.7 EMC77521.1 - 0.0018 18.1 2.2 8.5 6.3 0.1 4.0 3 1 1 4 4 4 2 8-oxoguanine DNA glycosylase, N-terminal domain Sec16_C PF12931.2 EMC77522.1 - 1.7e-33 116.6 0.0 2.4e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EMC77522.1 - 5e-20 71.6 0.0 8.2e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region RasGEF PF00617.14 EMC77523.1 - 1.8e-57 194.1 0.2 4.3e-57 192.8 0.1 1.6 1 1 0 1 1 1 1 RasGEF domain PH PF00169.24 EMC77523.1 - 3.3e-05 24.0 0.1 7.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC77523.1 - 0.014 15.6 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Fibrinogen_C PF00147.13 EMC77524.1 - 1e-74 251.1 9.9 1.4e-74 250.6 6.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain zf-C4H2 PF10146.4 EMC77524.1 - 0.028 14.4 0.3 0.044 13.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Fer4_NifH PF00142.13 EMC77524.1 - 0.21 10.7 1.1 0.32 10.1 0.8 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2115 PF09888.4 EMC77524.1 - 0.35 10.9 5.5 0.54 10.3 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1193 PF06702.7 EMC77525.1 - 8.1e-91 303.3 0.0 1.1e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 EMC77525.1 - 0.0017 17.1 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein Torsin PF06309.6 EMC77527.1 - 4.9e-55 184.8 0.8 8.1e-55 184.1 0.6 1.3 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.1 EMC77527.1 - 2.9e-05 24.2 0.1 0.0033 17.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EMC77527.1 - 0.00032 20.8 0.0 0.00048 20.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 EMC77527.1 - 0.024 13.5 0.1 0.12 11.2 0.1 1.8 1 1 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 EMC77527.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EMC77527.1 - 0.13 11.8 0.1 0.41 10.2 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Pkinase_Tyr PF07714.12 EMC77528.1 - 7.6e-98 326.7 0.0 1.2e-97 326.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77528.1 - 1e-49 169.0 0.0 3e-49 167.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain F_actin_bind PF08919.5 EMC77528.1 - 1.9e-31 108.0 0.0 3.9e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.19 EMC77528.1 - 1.9e-24 85.2 0.1 4.6e-24 84.0 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC77528.1 - 2.5e-12 45.9 0.0 4.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC77528.1 - 2e-09 36.8 0.0 3.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC77528.1 - 7.1e-08 31.8 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC77528.1 - 3.6e-06 27.0 0.8 1.1e-05 25.5 0.6 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_6 PF12913.2 EMC77528.1 - 0.0055 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain of the SH3b1 type Kinase-like PF14531.1 EMC77528.1 - 0.0061 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like GRP PF07172.6 EMC77528.1 - 0.047 14.1 1.2 0.14 12.6 0.8 1.8 1 0 0 1 1 1 0 Glycine rich protein family MBOAT PF03062.14 EMC77529.1 - 2.6e-41 141.8 36.0 2.6e-41 141.8 24.9 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Band_7 PF01145.20 EMC77530.1 - 1.6e-28 99.8 0.0 2.5e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMC77530.1 - 0.0014 18.2 0.2 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family OST-HTH PF12872.2 EMC77531.1 - 0.00063 19.5 0.0 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 OST-HTH/LOTUS domain TUDOR PF00567.19 EMC77532.1 - 3.3e-14 52.7 0.1 7.1e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 Tudor domain FAM163 PF15069.1 EMC77533.1 - 2.9e-47 160.8 1.2 3.3e-47 160.6 0.8 1.0 1 0 0 1 1 1 1 FAM163 family BSP_II PF05432.6 EMC77533.1 - 0.00036 19.9 0.0 0.00036 19.9 0.0 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF4006 PF13179.1 EMC77533.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) EphA2_TM PF14575.1 EMC77533.1 - 0.01 16.2 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_LMP2 PF07415.6 EMC77533.1 - 0.01 14.4 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Myc_N PF01056.13 EMC77533.1 - 0.028 13.6 0.1 0.029 13.5 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EMC77533.1 - 0.095 12.2 1.6 0.13 11.8 1.1 1.1 1 0 0 1 1 1 0 Nucleoplasmin 7TM_GPCR_Srv PF10323.4 EMC77533.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4589 PF15252.1 EMC77533.1 - 0.96 9.2 4.4 1.2 8.8 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) HCV_NS4a PF01006.15 EMC77533.1 - 1.4 8.5 4.2 2 7.9 2.2 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a FAM176 PF14851.1 EMC77533.1 - 4.3 6.9 6.3 7.1 6.2 4.4 1.4 1 1 0 1 1 1 0 FAM176 family TSP_1 PF00090.14 EMC77534.1 - 4.9e-26 90.5 118.2 3.3e-07 30.2 8.2 9.2 8 1 0 8 8 8 7 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 EMC77534.1 - 7.5e-25 87.0 0.0 1.2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.6 EMC77534.1 - 7.3e-11 42.1 9.7 7.3e-11 42.1 6.7 3.1 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain LAP1C PF05609.7 EMC77535.1 - 1.4e-90 304.2 0.1 1.5e-90 304.1 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Mito_morph_reg PF14972.1 EMC77535.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator MotCF PF09158.5 EMC77535.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal LAP1C PF05609.7 EMC77536.1 - 1.6e-110 370.0 0.2 1.7e-110 369.8 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) CAP_GLY PF01302.20 EMC77537.1 - 1.9e-21 75.4 0.1 3.3e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Curto_V3 PF07436.6 EMC77537.1 - 0.85 9.7 4.1 3.6 7.7 0.1 3.3 3 0 0 3 3 3 0 Curtovirus V3 protein Evr1_Alr PF04777.8 EMC77538.1 - 3e-26 91.1 0.1 2.5e-25 88.2 0.0 2.2 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.15 EMC77538.1 - 4.3e-05 23.1 0.0 0.00081 19.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Zn-ribbon_8 PF09723.5 EMC77538.1 - 0.44 10.5 2.2 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain LIM PF00412.17 EMC77539.1 - 1.8e-32 111.1 19.6 1.1e-16 60.5 2.1 2.2 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 EMC77539.1 - 2.1e-21 75.2 2.4 3.5e-21 74.5 1.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77539.1 - 0.00013 21.6 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain PSP1 PF04468.7 EMC77539.1 - 0.071 13.0 0.1 0.26 11.2 0.1 2.0 1 1 0 1 1 1 0 PSP1 C-terminal conserved region Orbi_VP3 PF01700.11 EMC77539.1 - 0.13 9.6 0.0 0.18 9.2 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein PHF5 PF03660.9 EMC77539.1 - 0.52 10.3 9.8 0.037 14.0 2.0 2.2 1 1 1 2 2 2 0 PHF5-like protein zf-RING_5 PF14634.1 EMC77539.1 - 4.8 6.9 0.0 4.8 6.9 0.0 3.6 2 1 0 2 2 2 0 zinc-RING finger domain DUF164 PF02591.10 EMC77539.1 - 7.9 6.3 10.0 9.9 6.0 1.1 2.8 2 0 0 2 2 2 0 Putative zinc ribbon domain Ank_4 PF13637.1 EMC77540.1 - 2.1e-21 75.8 1.1 2.1e-14 53.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC77540.1 - 3.9e-21 75.1 0.1 6e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC77540.1 - 5.2e-20 70.1 0.3 5e-09 35.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMC77540.1 - 1.4e-18 66.5 0.1 1.7e-11 43.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77540.1 - 1.1e-14 53.0 0.3 4e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat ACBP PF00887.14 EMC77540.1 - 2.7e-14 52.5 0.1 4.6e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein EXS PF03124.9 EMC77541.1 - 2.2e-116 388.6 22.8 3.2e-116 388.1 15.8 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EMC77541.1 - 6.2e-22 78.6 10.8 6.2e-22 78.6 7.5 2.8 3 1 0 3 3 3 1 SPX domain DUF1154 PF06631.6 EMC77541.1 - 0.11 12.1 0.1 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) PDZ PF00595.19 EMC77542.1 - 8.1e-11 41.9 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC77542.1 - 0.00094 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Syntaxin-6_N PF09177.6 EMC77544.1 - 3e-25 88.4 0.8 3e-25 88.4 0.5 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EMC77544.1 - 1.2e-15 56.9 3.4 1.2e-15 56.9 2.3 2.0 2 0 0 2 2 2 1 SNARE domain DUF3753 PF12575.3 EMC77544.1 - 0.015 15.0 2.9 0.052 13.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Fusion_gly PF00523.13 EMC77544.1 - 0.041 11.9 0.2 0.071 11.1 0.2 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 UPF0184 PF03670.8 EMC77544.1 - 0.065 13.4 0.3 0.61 10.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) FliD_C PF07195.7 EMC77544.1 - 0.084 12.1 3.9 2.2 7.5 0.0 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TBPIP PF07106.8 EMC77544.1 - 0.096 12.2 7.4 0.056 12.9 0.3 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rifin_STEVOR PF02009.11 EMC77544.1 - 0.11 12.0 0.4 0.17 11.5 0.2 1.4 1 1 0 1 1 1 0 Rifin/stevor family Syntaxin PF00804.20 EMC77544.1 - 0.19 11.9 6.3 0.15 12.2 0.3 2.8 1 1 1 2 2 2 0 Syntaxin DUF4492 PF14899.1 EMC77544.1 - 0.19 11.2 3.2 0.53 9.8 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Ran-binding PF05508.6 EMC77544.1 - 0.32 9.8 3.7 0.15 10.9 0.6 1.7 2 0 0 2 2 2 0 RanGTP-binding protein Prominin PF05478.6 EMC77544.1 - 0.55 7.7 6.9 0.24 8.9 0.9 1.9 1 1 1 2 2 2 0 Prominin GP41 PF00517.12 EMC77544.1 - 1.2 8.7 8.4 3.7 7.0 0.4 2.6 1 1 1 2 2 2 0 Retroviral envelope protein EMP24_GP25L PF01105.19 EMC77544.1 - 1.6 8.4 4.8 1.7 8.3 2.3 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Cortex-I_coil PF09304.5 EMC77544.1 - 3.1 7.8 9.4 6.7 6.8 0.4 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil CENP-F_leu_zip PF10473.4 EMC77544.1 - 3.4 7.5 9.7 12 5.8 0.3 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3552 PF12072.3 EMC77544.1 - 7.1 5.7 9.3 17 4.5 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) zf-H2C2_2 PF13465.1 EMC77545.1 - 3.7e-39 131.1 45.7 2.3e-07 30.7 0.7 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC77545.1 - 1.3e-28 97.5 42.0 0.00033 20.8 0.8 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77545.1 - 7.4e-23 79.1 39.6 0.00029 20.9 0.3 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC77545.1 - 2.7e-11 43.2 23.1 0.25 11.5 0.0 7.5 7 1 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EMC77545.1 - 1.5e-09 37.6 18.5 0.038 14.0 0.3 6.1 5 1 1 6 6 6 2 zinc-finger zf-C2H2_6 PF13912.1 EMC77545.1 - 9.1e-08 31.7 33.7 0.013 15.3 0.5 7.3 7 0 0 7 7 7 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EMC77545.1 - 1.1e-07 31.6 28.3 0.35 10.8 0.1 6.3 6 1 0 6 6 5 4 Zinc ribbon domain zf-Di19 PF05605.7 EMC77545.1 - 2.7e-05 24.1 26.0 0.00074 19.5 0.4 4.7 2 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 EMC77545.1 - 0.0015 18.2 18.6 0.12 12.0 0.6 4.7 4 3 1 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMC77545.1 - 0.0018 17.9 13.2 21 4.9 0.0 6.1 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 C1_3 PF07649.7 EMC77545.1 - 0.016 15.2 22.2 11 6.2 0.0 6.1 6 0 0 6 6 6 0 C1-like domain Rad50_zn_hook PF04423.9 EMC77545.1 - 0.019 14.4 2.0 11 5.5 0.0 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif Ribosomal_L44 PF00935.14 EMC77545.1 - 0.038 13.9 1.6 0.038 13.9 1.1 4.8 3 1 3 6 6 6 0 Ribosomal protein L44 DZR PF12773.2 EMC77545.1 - 0.093 12.5 22.3 1.5e+04 -6.5 15.4 4.0 1 1 0 1 1 0 0 Double zinc ribbon Rep_fac-A_C PF08646.5 EMC77545.1 - 0.11 12.2 11.5 8.4 6.0 0.9 4.3 1 1 4 5 5 5 0 Replication factor-A C terminal domain zf-IS66 PF13005.2 EMC77545.1 - 0.14 12.1 21.7 11 6.0 0.0 6.2 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 DUF164 PF02591.10 EMC77545.1 - 0.22 11.4 17.9 4.3 7.2 0.5 5.6 5 1 1 6 6 6 0 Putative zinc ribbon domain C1_4 PF07975.7 EMC77545.1 - 0.24 11.4 23.3 9.6 6.3 2.4 5.2 2 2 4 6 6 6 0 TFIIH C1-like domain zf-met PF12874.2 EMC77545.1 - 0.28 11.4 19.9 1.6 9.0 0.0 6.1 6 1 0 6 6 5 0 Zinc-finger of C2H2 type FYVE PF01363.16 EMC77545.1 - 0.36 10.7 26.6 6 6.8 7.1 5.1 1 1 2 3 3 3 0 FYVE zinc finger FYDLN_acid PF09538.5 EMC77545.1 - 0.36 11.4 9.4 40 4.8 1.4 4.7 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF2225 PF09986.4 EMC77545.1 - 0.44 9.9 13.8 0.71 9.2 0.2 4.0 3 2 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn_Tnp_IS1595 PF12760.2 EMC77545.1 - 0.59 9.9 28.6 0.88 9.4 2.2 4.2 2 2 2 4 4 4 0 Transposase zinc-ribbon domain zf-trcl PF13451.1 EMC77545.1 - 0.95 9.1 0.1 0.95 9.1 0.1 5.2 4 2 0 4 4 4 0 Probable zinc-binding domain BolA PF01722.13 EMC77545.1 - 1.2 9.1 5.5 50 3.9 0.2 3.7 2 2 3 5 5 5 0 BolA-like protein Zn_ribbon_2 PF12674.2 EMC77545.1 - 1.6 9.1 8.8 3.7 7.9 0.2 3.7 3 1 1 4 4 4 0 Putative zinc ribbon domain zf-FPG_IleRS PF06827.9 EMC77545.1 - 1.8 8.2 17.4 8.5 6.1 0.0 5.9 5 1 1 6 6 6 0 Zinc finger found in FPG and IleRS Zn_ribbon_recom PF13408.1 EMC77545.1 - 2 8.7 21.8 4.7 7.5 0.5 4.4 3 1 1 4 4 4 0 Recombinase zinc beta ribbon domain zf-P11 PF03854.9 EMC77545.1 - 2.1 7.8 0.0 2.1 7.8 0.0 3.7 6 0 0 6 6 5 0 P-11 zinc finger zf-ISL3 PF14690.1 EMC77545.1 - 2.6 8.1 26.1 6.5 6.8 0.7 6.3 5 1 1 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 E6 PF00518.12 EMC77545.1 - 3.4 8.0 8.4 11 6.3 0.1 3.4 2 1 0 3 3 3 0 Early Protein (E6) GAGA PF09237.6 EMC77545.1 - 3.9 7.1 17.2 5.4 6.6 0.2 4.6 1 1 3 5 5 5 0 GAGA factor XPA_N PF01286.13 EMC77545.1 - 5.5 6.7 23.4 3.3 7.4 0.1 5.9 6 0 0 6 6 6 0 XPA protein N-terminal OrfB_Zn_ribbon PF07282.6 EMC77545.1 - 6 6.5 23.5 7 6.3 1.3 5.1 3 1 1 5 5 5 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 EMC77545.1 - 6.2 6.2 21.6 46 3.4 3.1 5.7 5 1 1 6 6 6 0 TFIIB zinc-binding zf-met2 PF12907.2 EMC77545.1 - 9.5 6.2 16.3 22 5.1 0.0 5.5 6 1 1 7 7 6 0 Zinc-binding Gln-synt_C PF00120.19 EMC77546.1 - 1.1e-65 221.3 0.0 1.4e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EMC77546.1 - 1.1e-20 72.9 0.0 1.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RGS PF00615.14 EMC77547.1 - 2.5e-08 34.0 0.2 0.00088 19.3 0.0 3.3 3 0 0 3 3 3 2 Regulator of G protein signaling domain DED PF01335.16 EMC77548.1 - 0.079 13.0 0.3 0.091 12.8 0.2 1.1 1 0 0 1 1 1 0 Death effector domain Ank_2 PF12796.2 EMC77549.1 - 4.2e-61 203.2 9.9 1.6e-15 57.1 0.1 5.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EMC77549.1 - 2.3e-48 159.6 0.5 1.8e-07 30.6 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EMC77549.1 - 3.1e-44 148.5 0.5 5.9e-09 36.2 0.0 7.4 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77549.1 - 2.9e-36 119.8 0.0 0.00026 20.9 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EMC77549.1 - 3.2e-35 119.3 0.6 2.4e-07 30.8 0.0 6.9 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Pkinase PF00069.20 EMC77549.1 - 1.2e-11 44.2 0.1 1.7e-10 40.4 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EMC77549.1 - 7.5e-11 41.9 1.4 2.5e-10 40.2 0.5 2.3 2 0 0 2 2 2 1 Ribonuclease 2-5A Kdo PF06293.9 EMC77549.1 - 1.2e-07 30.9 0.6 7.2e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EMC77549.1 - 1.9e-05 23.8 0.0 4.4e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Shigella_OspC PF06128.6 EMC77549.1 - 0.015 14.8 0.1 5 6.5 0.0 2.8 2 1 0 2 2 2 0 Shigella flexneri OspC protein Choline_kinase PF01633.15 EMC77549.1 - 0.04 13.5 0.2 0.094 12.2 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EMC77549.1 - 0.057 13.1 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cor1 PF04803.7 EMC77549.1 - 0.084 12.6 0.6 0.28 10.9 0.4 1.9 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region RGS PF00615.14 EMC77550.1 - 2.9e-37 127.3 4.3 3.6e-37 127.0 3.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 EMC77551.1 - 1.2e-38 131.8 2.4 1.4e-38 131.6 1.7 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain CENP-L PF13092.1 EMC77552.1 - 5.4e-34 117.3 0.1 7.3e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Kelch_1 PF01344.20 EMC77553.1 - 6.9e-91 297.6 13.7 5.1e-17 61.1 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC77553.1 - 1.7e-56 186.2 6.5 6.5e-10 38.7 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EMC77553.1 - 1.5e-40 136.7 5.9 2.2e-07 30.5 0.0 6.3 3 1 3 6 6 6 6 Galactose oxidase, central domain BACK PF07707.10 EMC77553.1 - 6.8e-38 128.6 0.3 1.3e-37 127.7 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 EMC77553.1 - 1.2e-36 124.0 15.0 6.2e-06 26.2 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 EMC77553.1 - 1.2e-33 115.4 0.3 2.6e-33 114.3 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 EMC77553.1 - 7e-32 107.9 6.4 1e-06 28.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EMC77553.1 - 2.8e-09 36.7 12.2 0.12 12.3 0.0 6.2 7 0 0 7 7 7 4 Kelch motif N-glycanase_C PF09113.5 EMC77553.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal Varsurf_PPLC PF03490.8 EMC77553.1 - 0.094 12.4 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C PQQ_3 PF13570.1 EMC77553.1 - 4.3 7.7 14.3 1.2 9.5 0.4 4.4 4 0 0 4 4 4 0 PQQ-like domain DUF2452 PF10504.4 EMC77554.1 - 2.1e-60 202.6 0.1 2.4e-60 202.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) 2OG-FeII_Oxy_3 PF13640.1 EMC77555.1 - 8.2e-15 55.1 0.0 1.8e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMC77555.1 - 1.4e-06 28.5 0.0 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMC77555.1 - 0.00074 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Capsid_NCLDV PF04451.7 EMC77555.1 - 0.043 12.8 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein TPR_2 PF07719.12 EMC77555.1 - 0.089 12.7 1.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PsaX PF08078.7 EMC77555.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 PsaX family TPR_11 PF13414.1 EMC77555.1 - 0.17 11.5 1.0 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 TPR repeat PMP22_Claudin PF00822.15 EMC77556.1 - 2.3e-16 59.9 2.4 3e-16 59.5 1.6 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC77556.1 - 2.3e-10 40.4 0.7 4.1e-10 39.6 0.4 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 EMC77556.1 - 0.0024 17.9 0.8 0.003 17.6 0.5 1.3 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 EMC77556.1 - 0.025 13.8 0.4 0.043 13.0 0.2 1.4 1 1 0 1 1 1 0 Clc-like PIRT PF15099.1 EMC77556.1 - 0.18 11.0 0.1 0.18 11.0 0.1 1.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Pro_isomerase PF00160.16 EMC77557.1 - 2.2e-46 157.8 0.0 2.5e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DFP PF04127.10 EMC77558.1 - 3.4e-11 43.1 0.0 4.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein TPR_12 PF13424.1 EMC77559.1 - 1.8e-06 27.7 0.4 0.0035 17.2 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC77559.1 - 0.017 14.7 2.1 5.1 6.8 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 EMC77559.1 - 0.05 13.2 0.8 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EMC77560.1 - 7.2e-156 519.2 25.8 8.8e-156 518.9 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC77560.1 - 1.2e-19 70.2 35.2 4.5e-18 65.0 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC77560.1 - 0.00017 20.1 34.6 0.00056 18.4 4.8 3.6 2 1 0 3 3 3 2 MFS/sugar transport protein 60KD_IMP PF02096.15 EMC77560.1 - 0.0052 16.4 1.1 0.0052 16.4 0.8 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein Syndecan PF01034.15 EMC77560.1 - 0.24 11.0 2.9 9.6 5.9 0.6 3.1 2 0 0 2 2 2 0 Syndecan domain Pox_A21 PF05323.7 EMC77561.1 - 4.3 7.7 5.9 2.5 8.5 0.4 3.2 1 1 0 3 3 3 0 Poxvirus A21 Protein zf-H2C2_2 PF13465.1 EMC77562.1 - 6.9e-26 89.2 32.0 1.4e-07 31.4 1.5 5.2 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC77562.1 - 1.4e-19 69.1 38.6 8.3e-06 25.8 0.9 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77562.1 - 9.2e-15 53.8 36.7 9.4e-05 22.4 1.2 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC77562.1 - 6.9e-06 25.7 22.6 0.31 11.0 0.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 EMC77562.1 - 7.3e-06 26.0 22.6 0.0001 22.3 4.1 3.3 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EMC77562.1 - 0.001 18.6 1.7 8.2 6.2 0.0 4.0 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C4_ClpX PF06689.8 EMC77562.1 - 0.071 12.6 3.2 1.7 8.2 0.2 2.5 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-C2H2_jaz PF12171.3 EMC77562.1 - 0.074 13.2 20.7 1.6 8.9 1.4 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC77562.1 - 0.15 12.1 22.0 0.28 11.3 1.1 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_2 PF13240.1 EMC77562.1 - 0.17 11.3 0.0 0.17 11.3 0.0 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMC77562.1 - 0.27 11.2 18.3 8.5 6.4 2.3 4.1 2 1 1 3 3 3 0 Zinc ribbon domain PyrI_C PF02748.10 EMC77562.1 - 0.44 10.0 0.1 0.44 10.0 0.1 3.2 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF164 PF02591.10 EMC77562.1 - 1.7 8.5 9.9 2.2 8.1 0.4 3.3 2 1 1 3 3 3 0 Putative zinc ribbon domain zf-AN1 PF01428.11 EMC77562.1 - 2.3 8.1 10.1 7.1 6.5 0.1 3.8 3 1 0 3 3 3 0 AN1-like Zinc finger IBR PF01485.16 EMC77562.1 - 2.4 8.1 16.0 95 2.9 9.3 3.3 1 1 1 2 2 2 0 IBR domain zf-met PF12874.2 EMC77562.1 - 3.4 8.0 31.3 0.52 10.5 2.0 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-MIZ PF02891.15 EMC77562.1 - 9.2 5.8 11.7 0.38 10.2 2.4 2.7 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Trypsin PF00089.21 EMC77563.1 - 2.9e-45 154.5 0.0 3.2e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin UCH PF00443.24 EMC77565.1 - 1.4e-38 132.5 1.2 1.4e-38 132.5 0.8 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC77565.1 - 4.9e-20 72.1 18.0 3.2e-19 69.4 0.3 3.8 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EMC77565.1 - 2.4e-08 34.2 1.7 0.00094 19.5 0.0 4.2 4 0 0 4 4 4 2 DUSP domain ubiquitin PF00240.18 EMC77565.1 - 1.9e-05 23.9 0.0 4.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Collagen PF01391.13 EMC77566.1 - 0.02 14.4 4.7 0.083 12.4 3.2 2.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Peptidase_M13_N PF05649.8 EMC77567.1 - 5e-128 427.4 1.0 6.4e-128 427.1 0.7 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EMC77567.1 - 1.6e-66 223.4 0.0 4.2e-66 222.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Linker_histone PF00538.14 EMC77568.1 - 1.1e-42 143.9 0.4 1.8e-15 56.8 0.0 3.4 3 0 0 3 3 3 3 linker histone H1 and H5 family YL1 PF05764.8 EMC77568.1 - 0.0023 17.6 13.9 0.0023 17.6 9.6 3.1 2 1 0 2 2 1 1 YL1 nuclear protein SDA1 PF05285.7 EMC77568.1 - 0.0067 15.7 3.0 0.0067 15.7 2.1 2.5 3 0 0 3 3 3 2 SDA1 Daxx PF03344.10 EMC77568.1 - 0.026 13.0 27.8 0.023 13.2 5.0 2.3 2 0 0 2 2 2 0 Daxx Family Transglycosylas PF06737.9 EMC77568.1 - 0.076 13.3 3.2 5.4 7.3 0.0 3.5 4 0 0 4 4 4 0 Transglycosylase-like domain Nop14 PF04147.7 EMC77568.1 - 0.13 10.1 35.1 0.11 10.3 10.0 2.2 2 0 0 2 2 2 0 Nop14-like family DUF1510 PF07423.6 EMC77568.1 - 0.18 11.1 37.2 0.07 12.5 11.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2890 PF11081.3 EMC77568.1 - 0.19 11.7 37.0 0.072 13.1 11.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF1266 PF06889.6 EMC77568.1 - 0.47 10.2 3.9 0.79 9.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) CDC45 PF02724.9 EMC77568.1 - 0.87 7.5 26.5 0.089 10.8 6.3 2.3 2 0 0 2 2 2 0 CDC45-like protein AUX_IAA PF02309.11 EMC77568.1 - 2.5 7.8 24.7 0.085 12.5 4.7 2.6 2 1 0 2 2 2 0 AUX/IAA family RRN3 PF05327.6 EMC77568.1 - 6.3 4.7 15.9 1.3 7.0 2.1 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Kinesin PF00225.18 EMC77570.1 - 1.4e-29 102.8 0.0 1.5e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain AAA_10 PF12846.2 EMC77570.1 - 0.00027 20.4 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EMC77570.1 - 0.0043 17.1 0.0 0.0046 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMC77570.1 - 0.0067 16.0 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMC77570.1 - 0.019 14.9 0.0 0.021 14.8 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EMC77570.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 TMF_TATA_bd PF12325.3 EMC77571.1 - 0.076 12.7 0.8 0.076 12.7 0.5 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF745 PF05335.8 EMC77571.1 - 0.28 10.6 4.7 0.4 10.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BBP1_C PF15272.1 EMC77571.1 - 0.34 10.4 11.1 0.023 14.2 3.4 1.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF641 PF04859.7 EMC77571.1 - 0.92 9.2 7.0 3.1 7.5 4.7 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EMC77571.1 - 2.4 7.7 10.5 0.46 9.9 2.4 2.4 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 EMC77571.1 - 3.2 7.2 9.7 4.9 6.6 6.6 1.4 1 1 0 1 1 1 0 IncA protein DUF4570 PF15134.1 EMC77571.1 - 3.3 7.6 8.5 5.1 6.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) APG6 PF04111.7 EMC77571.1 - 3.9 6.4 9.0 6 5.8 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 EMC77571.1 - 5.6 7.2 7.4 7.8 6.7 5.1 1.3 1 0 0 1 1 1 0 AAA domain DDOST_48kD PF03345.9 EMC77572.1 - 2.1e-150 500.9 0.0 2.4e-150 500.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta UBA PF00627.26 EMC77573.1 - 0.00066 19.4 0.1 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain FF PF01846.14 EMC77575.1 - 1.4e-17 63.3 9.2 3.1e-09 36.6 2.6 2.4 2 0 0 2 2 2 2 FF domain WW PF00397.21 EMC77575.1 - 3.5e-05 23.5 0.1 3.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 WW domain Glutaredoxin PF00462.19 EMC77576.1 - 4.3e-38 129.1 0.0 1.6e-17 63.1 0.0 2.9 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 EMC77576.1 - 1.4e-06 27.8 0.0 9.7e-06 25.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin SH3BGR PF04908.10 EMC77576.1 - 4.9e-05 23.2 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Thioredoxin_2 PF13098.1 EMC77576.1 - 0.0012 19.0 0.0 0.03 14.5 0.0 2.9 2 1 2 4 4 4 1 Thioredoxin-like domain DNA_processg_A PF02481.10 EMC77576.1 - 0.0033 16.3 0.0 1.4 7.7 0.0 3.1 4 0 0 4 4 4 2 DNA recombination-mediator protein A ArsC PF03960.10 EMC77576.1 - 0.0041 17.1 0.0 1.7 8.7 0.0 2.7 3 0 0 3 3 3 1 ArsC family GST_N_3 PF13417.1 EMC77576.1 - 0.033 14.4 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain TrbC_Ftype PF09673.5 EMC77576.1 - 0.037 13.6 0.0 0.15 11.7 0.0 2.0 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Fe-ADH PF00465.14 EMC77576.1 - 0.066 11.8 0.0 0.89 8.1 0.0 2.0 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Ras PF00071.17 EMC77577.1 - 2.1e-56 189.8 0.1 2.4e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77577.1 - 1.6e-18 67.3 0.0 2.5e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC77577.1 - 9.5e-13 47.7 0.1 1.1e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC77577.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC77577.1 - 0.002 17.3 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EMC77577.1 - 0.029 13.8 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation APP_N PF02177.11 EMC77577.1 - 0.063 13.2 0.3 0.71 9.8 0.0 2.5 3 0 0 3 3 3 0 Amyloid A4 N-terminal heparin-binding FeoB_N PF02421.13 EMC77577.1 - 0.086 12.1 0.2 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF92 PF01940.11 EMC77578.1 - 1.2e-72 243.7 4.7 1.9e-72 243.1 3.3 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 zf-C3H1 PF10650.4 EMC77580.1 - 1.2e-09 37.3 7.4 2.9e-09 36.2 5.2 1.7 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_17 PF13431.1 EMC77580.1 - 8.7e-07 28.6 3.9 0.019 15.1 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC77580.1 - 2.1e-06 27.9 7.2 0.27 11.6 0.0 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC77580.1 - 1.1e-05 25.6 7.0 0.21 12.3 0.0 6.4 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC77580.1 - 2.7e-05 23.7 13.9 0.00065 19.2 0.4 5.2 5 2 1 6 6 6 3 TPR repeat TPR_16 PF13432.1 EMC77580.1 - 0.027 15.1 0.6 1.6 9.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC77580.1 - 0.073 13.0 5.7 0.24 11.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.1 EMC77581.1 - 2.2e-87 286.7 62.1 4.9e-15 55.0 2.0 8.5 2 2 8 10 10 10 9 Leucine rich repeat LRR_4 PF12799.2 EMC77581.1 - 1.4e-47 158.6 36.7 9.5e-09 34.6 0.2 9.5 6 3 2 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC77581.1 - 8.5e-37 125.7 0.0 2.1e-12 46.8 0.0 4.5 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC77581.1 - 9e-31 101.1 42.7 0.03 14.2 0.3 17.4 17 1 1 18 18 18 11 Leucine Rich Repeat LRR_7 PF13504.1 EMC77581.1 - 4.6e-19 65.1 33.9 0.43 10.9 0.3 15.2 15 0 0 15 15 15 5 Leucine rich repeat 7tm_1 PF00001.16 EMC77581.1 - 9.1e-16 57.7 15.1 1.3e-15 57.2 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_6 PF13516.1 EMC77581.1 - 1.9e-10 39.6 36.1 0.28 11.3 0.2 14.0 13 2 2 15 15 15 2 Leucine Rich repeat LRR_9 PF14580.1 EMC77581.1 - 2.5e-09 36.9 5.4 0.21 11.1 0.0 4.7 1 1 2 4 4 4 4 Leucine-rich repeat 7TM_GPCR_Srx PF10328.4 EMC77581.1 - 0.1 11.7 15.4 0.27 10.3 10.7 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Tetraspannin PF00335.15 EMC77582.1 - 7.7e-51 172.4 21.7 9.2e-51 172.2 15.1 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 EMC77582.1 - 0.0024 17.6 9.7 0.032 13.9 3.1 2.5 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Tic20 PF09685.5 EMC77582.1 - 2.5 8.0 14.1 0.027 14.4 3.4 2.0 2 0 0 2 2 2 0 Tic20-like protein Y_phosphatase PF00102.22 EMC77583.1 - 9.4e-78 260.7 1.1 1.6e-77 260.0 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC77583.1 - 0.00023 20.7 0.0 0.0006 19.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC77583.1 - 0.00098 19.4 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC77583.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate BtpA PF03437.10 EMC77584.1 - 1.5e-33 116.1 0.0 1.6e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 BtpA family Cyclin_N PF00134.18 EMC77585.1 - 4.7e-43 145.7 2.0 7.5e-43 145.1 1.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC77585.1 - 3.5e-10 39.8 0.2 1.4e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Prefoldin PF02996.12 EMC77586.1 - 3.6e-14 52.4 0.0 9.1e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EMC77586.1 - 4e-07 29.7 0.1 2.4e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EMC77586.1 - 0.012 16.5 0.2 0.012 16.5 0.1 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3835) Cupredoxin_1 PF13473.1 EMC77586.1 - 0.084 12.7 0.2 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 Cupredoxin-like domain zf-C2H2 PF00096.21 EMC77587.1 - 9.2e-30 101.1 74.2 2.4e-05 24.4 2.4 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77587.1 - 1e-26 91.2 70.7 0.00084 19.5 1.6 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC77587.1 - 7.7e-24 82.7 80.9 1.9e-08 34.1 1.7 12.8 13 0 0 13 13 12 7 Zinc-finger double domain zf-Di19 PF05605.7 EMC77587.1 - 1e-06 28.7 50.0 0.014 15.4 0.6 8.0 6 3 1 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EMC77587.1 - 0.00012 22.0 7.2 0.0016 18.5 1.8 10.0 10 0 0 10 10 10 4 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EMC77587.1 - 0.0016 18.4 41.6 2.3 8.3 1.2 9.9 5 3 3 9 9 9 3 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 EMC77587.1 - 0.0019 17.7 10.3 0.58 9.7 0.1 5.5 5 2 2 7 7 7 2 GAGA factor zf-C2H2_jaz PF12171.3 EMC77587.1 - 0.061 13.4 0.3 0.061 13.4 0.2 9.2 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding TerY-C PF15616.1 EMC77587.1 - 0.81 9.6 10.6 4.6 7.1 0.0 3.8 4 0 0 4 4 4 0 TerY-C metal binding domain zf-CHCC PF10276.4 EMC77587.1 - 0.97 9.3 26.9 0.7 9.7 0.1 6.4 6 0 0 6 6 6 0 Zinc-finger domain C1_3 PF07649.7 EMC77587.1 - 1.6 8.8 15.8 3.9 7.6 0.1 5.3 5 0 0 5 5 5 0 C1-like domain Rad50_zn_hook PF04423.9 EMC77587.1 - 3.8 7.0 13.9 1.5 8.3 0.1 5.5 5 0 0 5 5 5 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.2 EMC77588.1 - 1.7e-10 40.8 20.9 0.0048 16.9 0.8 5.2 3 2 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EMC77588.1 - 1.8e-08 34.2 27.4 0.07 13.5 1.0 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77588.1 - 6e-07 29.3 17.3 0.053 13.8 1.6 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC77588.1 - 1e-05 25.2 16.5 0.14 12.1 0.4 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 EMC77588.1 - 0.00072 19.6 7.2 0.021 14.9 1.5 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF678 PF05077.7 EMC77588.1 - 0.0012 18.8 1.3 3.5 7.6 0.0 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF678) DUF3222 PF11519.3 EMC77588.1 - 0.059 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) Homeobox PF00046.24 EMC77588.1 - 0.095 12.3 0.4 0.38 10.4 0.1 2.3 2 0 0 2 2 2 0 Homeobox domain zf-C2H2_jaz PF12171.3 EMC77588.1 - 0.13 12.4 16.1 0.21 11.7 0.7 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 EMC77588.1 - 0.2 11.1 2.2 2.3 7.7 0.1 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.11 EMC77588.1 - 0.43 10.4 5.4 0.54 10.1 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-H2C2_2 PF13465.1 EMC77588.1 - 1.1 9.7 14.0 1.2 9.6 0.1 5.0 5 0 0 5 5 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EMC77588.1 - 1.2 9.2 12.1 4.8 7.2 0.0 4.9 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_4 PF13894.1 EMC77589.1 - 2e-13 49.6 65.8 0.00056 20.0 1.4 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC77589.1 - 1.4e-09 37.7 70.6 0.043 14.1 2.7 8.6 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EMC77589.1 - 1.7e-06 27.9 68.6 0.011 15.9 0.1 8.8 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EMC77589.1 - 0.00013 22.0 12.7 0.00031 20.8 1.3 10.3 10 1 0 10 10 10 5 Zinc-finger double domain Dpy19 PF10034.4 EMC77590.1 - 3.7e-221 735.7 34.0 4.2e-221 735.5 23.6 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Cadherin PF00028.12 EMC77591.1 - 6.8e-219 708.9 17.4 7.5e-20 70.9 0.0 15.3 15 0 0 15 15 15 15 Cadherin domain Laminin_G_2 PF02210.19 EMC77591.1 - 1.7e-37 128.3 0.1 2.9e-21 75.8 0.0 3.0 2 1 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 EMC77591.1 - 2.9e-25 88.7 0.0 1.9e-11 44.0 0.0 3.0 2 1 0 2 2 2 2 Laminin G domain EGF PF00008.22 EMC77591.1 - 5.6e-12 45.3 48.4 1.5e-05 24.8 4.1 4.9 4 0 0 4 4 4 4 EGF-like domain Cadherin_C PF01049.12 EMC77591.1 - 2.2e-10 40.7 0.5 5e-10 39.6 0.3 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 EMC77591.1 - 2.5e-10 40.0 0.0 3.5e-06 26.7 0.0 6.4 8 0 0 8 8 8 1 Cadherin prodomain like Cadherin_2 PF08266.7 EMC77591.1 - 6.6e-09 35.2 0.0 0.064 12.8 0.0 7.1 8 0 0 8 8 8 1 Cadherin-like EGF_2 PF07974.8 EMC77591.1 - 0.00015 21.8 58.2 0.016 15.3 3.7 5.1 4 0 0 4 4 4 3 EGF-like domain PepSY PF03413.14 EMC77591.1 - 1.3 9.7 5.6 1.9e+02 2.7 0.1 5.0 4 1 0 4 4 4 0 Peptidase propeptide and YPEB domain cEGF PF12662.2 EMC77591.1 - 5.5 6.7 33.0 0.27 10.9 2.2 4.9 4 0 0 4 4 4 0 Complement Clr-like EGF-like dsDNA_bind PF01984.15 EMC77592.1 - 5e-31 106.8 5.0 5.7e-31 106.6 3.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain E_Pc_C PF06752.7 EMC77592.1 - 0.05 13.1 0.4 0.057 12.9 0.3 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Ank PF00023.25 EMC77593.1 - 5.5e-70 227.8 28.8 4.4e-11 42.0 0.1 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank_2 PF12796.2 EMC77593.1 - 2e-66 220.3 7.5 3.8e-21 75.2 1.5 7.3 3 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC77593.1 - 1.1e-50 168.5 20.9 4.6e-12 45.7 0.8 9.5 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC77593.1 - 1.3e-47 159.3 16.7 1.9e-10 40.9 0.2 9.2 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77593.1 - 1.1e-43 142.8 16.1 3.2e-06 26.8 0.1 11.2 11 0 0 11 11 11 8 Ankyrin repeat VPS9 PF02204.13 EMC77593.1 - 4.2e-24 84.5 1.0 1.9e-23 82.4 0.3 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF1320 PF07030.7 EMC77593.1 - 0.093 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Syntaxin_2 PF14523.1 EMC77594.1 - 3.8e-07 30.0 0.2 1.4e-06 28.2 0.2 1.8 2 0 0 2 2 2 1 Syntaxin-like protein DUF2493 PF10686.4 EMC77594.1 - 0.033 13.7 0.0 0.28 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2493) DUF1539 PF07560.6 EMC77594.1 - 0.037 13.9 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF2155 PF09923.4 EMC77594.1 - 0.039 14.0 0.4 6.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) CRF PF00473.12 EMC77594.1 - 0.18 11.8 2.7 0.16 12.1 0.7 1.8 2 0 0 2 2 2 0 Corticotropin-releasing factor family Syndecan PF01034.15 EMC77594.1 - 0.19 11.3 2.0 0.36 10.5 1.4 1.5 1 0 0 1 1 1 0 Syndecan domain TUDOR PF00567.19 EMC77596.1 - 3.1e-11 43.1 1.9 3.8e-11 42.8 1.3 1.1 1 0 0 1 1 1 1 Tudor domain TUDOR PF00567.19 EMC77597.1 - 1.5e-09 37.7 0.1 3.6e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Tudor domain DEAD PF00270.24 EMC77597.1 - 9.4e-08 31.7 0.0 2.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AA_permease_2 PF13520.1 EMC77598.1 - 2e-64 217.6 46.7 2.6e-64 217.3 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC77598.1 - 1.8e-27 95.8 42.9 2.3e-27 95.4 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease HHH_2 PF12826.2 EMC77600.1 - 3.3e-09 36.5 0.0 6.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EMC77600.1 - 0.00055 20.0 0.0 0.00097 19.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.15 EMC77600.1 - 0.0099 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.18 EMC77600.1 - 0.054 13.2 0.3 3.4 7.5 0.0 3.0 3 1 0 3 3 3 0 Helix-hairpin-helix motif BRO1 PF03097.13 EMC77601.1 - 8e-112 373.7 0.1 1e-111 373.3 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.11 EMC77601.1 - 9e-12 44.5 3.4 2.6e-11 43.1 2.3 1.9 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.19 EMC77601.1 - 2.6e-06 27.5 0.0 8.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) DUF372 PF04036.7 EMC77601.1 - 0.099 12.1 0.0 8.8 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF372) DUF1604 PF07713.8 EMC77602.1 - 1.5e-35 120.8 0.3 1.5e-35 120.8 0.2 3.8 5 0 0 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EMC77602.1 - 6.3e-07 29.0 0.2 6.3e-07 29.0 0.2 2.3 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 EMC77602.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 4.0 3 1 0 3 3 3 1 DExH-box splicing factor binding site RBP_receptor PF14752.1 EMC77602.1 - 1.9 6.7 1.3 3.5 5.8 0.9 1.3 1 0 0 1 1 1 0 Retinol binding protein receptor WD40 PF00400.27 EMC77603.1 - 3.3e-49 163.0 33.3 3.5e-10 39.3 2.7 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EMC77603.1 - 1.2e-06 26.9 6.8 0.14 10.2 0.1 4.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMC77603.1 - 1.4e-06 26.9 0.1 0.00099 17.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EMC77603.1 - 4.8e-05 22.9 0.0 6.8e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.6 EMC77603.1 - 0.00019 21.2 1.1 0.045 13.4 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ PF01011.16 EMC77603.1 - 0.0011 18.4 0.3 0.0042 16.5 0.0 2.1 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.1 EMC77603.1 - 0.0016 18.6 0.0 5.3 7.4 0.0 3.3 4 0 0 4 4 4 2 PQQ-like domain Fn3-like PF14310.1 EMC77603.1 - 0.16 11.9 0.2 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Fibronectin type III-like domain MmlI PF09448.5 EMC77603.1 - 0.24 11.1 2.4 12 5.6 0.1 3.8 1 1 4 5 5 5 0 Methylmuconolactone methyl-isomerase Ldl_recept_a PF00057.13 EMC77604.1 - 1.3e-39 133.7 83.5 8.7e-12 44.7 8.4 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A CUB PF00431.15 EMC77604.1 - 7.2e-19 67.8 0.1 3.6e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 CUB domain Zn_peptidase_2 PF04298.7 EMC77604.1 - 0.26 10.6 0.1 0.43 9.8 0.1 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase AA_permease_2 PF13520.1 EMC77605.1 - 6.3e-62 209.4 42.2 7.7e-62 209.1 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC77605.1 - 3.9e-36 124.4 35.5 4.8e-36 124.1 24.6 1.1 1 0 0 1 1 1 1 Amino acid permease bZIP_2 PF07716.10 EMC77606.1 - 3.6e-13 49.1 14.7 4e-12 45.7 10.2 2.2 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC77606.1 - 0.0011 18.8 9.7 0.0028 17.5 6.7 1.7 1 1 0 1 1 1 1 bZIP transcription factor IBB PF01749.15 EMC77606.1 - 0.015 15.4 11.6 0.027 14.6 8.1 1.4 1 0 0 1 1 1 0 Importin beta binding domain Hema_stalk PF08720.5 EMC77606.1 - 0.14 11.6 0.2 0.19 11.2 0.1 1.1 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk DUF4613 PF15390.1 EMC77606.1 - 0.4 8.7 2.7 0.58 8.2 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PAT1 PF09770.4 EMC77606.1 - 7.3 4.6 11.3 8.4 4.4 7.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 bZIP_2 PF07716.10 EMC77607.1 - 4.5e-16 58.4 17.0 6.2e-16 57.9 11.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC77607.1 - 5.6e-06 26.2 12.6 9.4e-06 25.4 8.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF572 PF04502.8 EMC77607.1 - 0.001 18.4 1.1 0.001 18.4 0.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) IncA PF04156.9 EMC77607.1 - 0.011 15.3 0.3 0.012 15.1 0.2 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EMC77607.1 - 0.02 12.7 5.6 0.024 12.5 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 EMC77607.1 - 0.022 12.9 1.2 0.024 12.8 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.17 EMC77607.1 - 0.032 14.2 7.8 0.051 13.6 5.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.12 EMC77607.1 - 0.041 14.1 7.6 0.073 13.3 5.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Atg14 PF10186.4 EMC77607.1 - 0.1 11.5 5.6 0.14 11.0 3.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EMC77607.1 - 0.2 11.1 7.4 0.23 10.9 4.3 1.6 1 1 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 EMC77607.1 - 0.3 10.0 5.9 0.35 9.8 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4094 PF13334.1 EMC77607.1 - 0.75 10.2 6.0 0.26 11.6 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) LAM_C PF12544.3 EMC77607.1 - 2.1 8.3 6.7 19 5.2 4.6 2.2 1 1 0 1 1 1 0 Lysine-2,3-aminomutase XhlA PF10779.4 EMC77607.1 - 4.2 7.3 5.9 7.6 6.5 4.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Peptidase_M24 PF00557.19 EMC77608.1 - 1.4e-46 158.6 0.0 4.3e-44 150.5 0.0 3.2 2 1 1 3 3 3 1 Metallopeptidase family M24 AMP_N PF05195.11 EMC77608.1 - 7.2e-41 138.7 0.0 1.2e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Sulfotransfer_2 PF03567.9 EMC77609.1 - 1.6e-41 142.6 3.6 1.8e-41 142.5 2.5 1.0 1 0 0 1 1 1 1 Sulfotransferase family TAF4 PF05236.9 EMC77610.1 - 1.8e-83 279.8 6.4 2.1e-83 279.6 4.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.12 EMC77610.1 - 3.9e-05 23.5 0.3 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 TATA box binding protein associated factor (TAF) SAGA-Tad1 PF12767.2 EMC77610.1 - 0.00042 20.0 3.3 0.0093 15.6 0.0 2.2 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit SprA-related PF12118.3 EMC77610.1 - 0.067 12.5 7.6 0.079 12.2 5.3 1.2 1 0 0 1 1 1 0 SprA-related family LSM14 PF12701.2 EMC77611.1 - 3.3e-42 142.2 0.0 7e-42 141.1 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EMC77611.1 - 6.7e-32 110.1 8.3 6.7e-32 110.1 5.7 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EMC77611.1 - 3.9e-06 26.6 0.0 7.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 EMC77611.1 - 0.98 9.9 18.5 9.3 6.8 0.3 2.6 2 0 0 2 2 2 0 Glycine rich protein family LIM PF00412.17 EMC77613.1 - 4.8e-36 122.6 37.3 3.9e-14 52.4 6.3 3.1 3 0 0 3 3 3 3 LIM domain UBACT PF02134.16 EMC77614.1 - 4.7e-27 93.3 0.1 8.2e-27 92.5 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EMC77614.1 - 2.9e-24 84.9 4.7 3.8e-24 84.5 0.9 2.4 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.16 EMC77614.1 - 3.9e-24 85.0 0.1 8.2e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 EMC77614.1 - 1.2e-22 79.0 2.4 1.2e-22 79.0 1.7 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site PDCD2_C PF04194.8 EMC77615.1 - 4e-52 176.1 0.1 6.4e-52 175.4 0.1 1.3 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain COesterase PF00135.23 EMC77616.1 - 3e-163 544.3 0.0 3.4e-163 544.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC77616.1 - 8.5e-08 32.0 1.3 3e-07 30.2 0.8 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC77616.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EMC77617.1 - 3e-29 102.1 0.0 3.7e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 EMC77618.1 - 1.1e-103 347.7 0.0 1.3e-103 347.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC77618.1 - 6.6e-09 35.6 1.0 3.5e-08 33.2 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC77618.1 - 0.0076 15.4 0.1 0.017 14.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC77618.1 - 0.092 12.5 0.4 0.13 12.0 0.3 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EMC77619.1 - 1.3e-127 426.7 0.0 1.6e-127 426.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC77619.1 - 3.6e-09 36.5 1.1 9e-09 35.2 0.7 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC77619.1 - 0.00012 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EMC77619.1 - 0.00093 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EMC77619.1 - 0.0047 16.6 0.0 0.0071 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EMC77619.1 - 0.062 11.9 0.1 0.16 10.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) COesterase PF00135.23 EMC77620.1 - 1.9e-158 528.5 0.0 2.4e-158 528.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC77620.1 - 8.8e-10 38.5 0.7 2.6e-09 36.9 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC77620.1 - 0.00027 20.2 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EMC77620.1 - 0.00053 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EMC77620.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 EMC77620.1 - 0.069 11.7 0.0 0.15 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) DUF59 PF01883.14 EMC77621.1 - 2.5e-05 24.1 0.0 8e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function DUF59 Ras PF00071.17 EMC77622.1 - 3.6e-31 107.7 0.0 5.1e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77622.1 - 6.9e-19 68.4 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC77622.1 - 0.0013 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EMC77622.1 - 0.0018 17.5 0.1 0.017 14.3 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EMC77622.1 - 0.0055 16.8 0.1 1.7 8.7 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EMC77622.1 - 0.013 15.8 1.0 0.052 13.8 0.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC77622.1 - 0.014 15.0 0.1 0.068 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMC77622.1 - 0.019 15.2 0.3 0.057 13.7 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EMC77622.1 - 0.024 14.5 0.1 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EMC77622.1 - 0.034 14.3 0.3 0.32 11.2 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.22 EMC77622.1 - 0.037 13.4 0.2 0.085 12.2 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 EMC77622.1 - 0.11 12.1 0.2 0.3 10.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PP2C PF00481.16 EMC77623.1 - 6.5e-40 137.1 0.0 7.5e-37 127.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF3071 PF11268.3 EMC77623.1 - 0.044 13.5 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Carb_anhydrase PF00194.16 EMC77624.1 - 3.7e-116 386.5 0.0 4.1e-116 386.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ThiF PF00899.16 EMC77625.1 - 1.3e-06 28.2 0.1 9.1e-06 25.5 0.0 2.4 3 0 0 3 3 3 1 ThiF family Transket_pyr PF02779.19 EMC77625.1 - 0.014 14.8 0.3 0.026 14.0 0.2 1.4 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain UPF0270 PF06794.7 EMC77625.1 - 0.096 12.4 0.1 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Arm PF00514.18 EMC77626.1 - 0.012 15.3 5.4 0.82 9.5 0.1 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EMC77626.1 - 0.064 12.9 8.4 7.3 6.3 0.0 4.0 4 1 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.1 EMC77626.1 - 0.074 12.9 1.6 3.9 7.4 0.1 3.1 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EMC77626.1 - 0.12 12.6 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats DLIC PF05783.6 EMC77627.1 - 1.9e-244 811.6 0.0 2.2e-244 811.4 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.22 EMC77627.1 - 0.0012 18.3 0.0 0.8 9.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EMC77627.1 - 0.0017 18.6 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 EMC77627.1 - 0.0022 18.5 0.1 0.028 14.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EMC77627.1 - 0.0041 16.6 0.2 0.0091 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EMC77627.1 - 0.011 15.9 0.0 0.031 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC77627.1 - 0.015 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EMC77627.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.16 EMC77627.1 - 0.028 13.6 0.2 0.4 9.9 0.0 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_10 PF12846.2 EMC77627.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EMC77627.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EMC77627.1 - 0.05 13.0 0.2 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EMC77627.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMC77627.1 - 0.067 12.6 0.2 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Kinesin PF00225.18 EMC77627.1 - 0.075 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain KaiC PF06745.8 EMC77627.1 - 0.082 12.0 0.1 0.18 10.8 0.1 1.6 1 1 0 1 1 1 0 KaiC AAA_24 PF13479.1 EMC77627.1 - 0.084 12.4 0.2 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMC77627.1 - 0.1 13.3 0.6 0.74 10.6 0.4 2.4 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMC77627.1 - 0.29 10.5 1.1 0.53 9.7 0.3 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MARVEL PF01284.18 EMC77628.1 - 1.1e-13 51.2 14.8 1.6e-13 50.6 10.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain YfhO PF09586.5 EMC77628.1 - 0.0016 16.5 0.5 0.0018 16.3 0.4 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO ABC2_membrane_5 PF13346.1 EMC77628.1 - 0.024 13.9 2.3 0.034 13.4 1.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein YbhQ PF11076.3 EMC77628.1 - 0.027 14.0 0.6 0.031 13.8 0.4 1.1 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ RseC_MucC PF04246.7 EMC77628.1 - 0.047 13.2 0.5 0.047 13.2 0.3 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NicO PF03824.11 EMC77628.1 - 0.18 11.0 4.2 0.07 12.4 0.3 1.8 1 1 2 3 3 3 0 High-affinity nickel-transport protein NfeD PF01957.13 EMC77628.1 - 0.91 9.6 6.4 1.9 8.5 2.4 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Neur_chan_memb PF02932.11 EMC77628.1 - 1.1 9.1 3.3 3 7.6 0.6 2.0 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MARVEL PF01284.18 EMC77629.1 - 1.7e-08 34.3 18.4 3.2e-08 33.5 12.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain PHO4 PF01384.15 EMC77629.1 - 0.064 11.8 3.7 0.077 11.6 2.6 1.0 1 0 0 1 1 1 0 Phosphate transporter family Cad PF03596.8 EMC77629.1 - 0.67 9.6 5.2 0.079 12.6 0.8 1.5 2 0 0 2 2 2 0 Cadmium resistance transporter O-antigen_lig PF13425.1 EMC77629.1 - 3.8 7.4 12.3 11 5.9 8.5 1.7 1 1 0 1 1 1 0 O-antigen ligase like membrane protein FA_desaturase PF00487.19 EMC77629.1 - 7.5 5.9 6.0 8.9 5.6 4.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase MARVEL PF01284.18 EMC77630.1 - 0.00057 19.7 18.5 0.0041 16.9 12.8 2.3 1 1 0 1 1 1 1 Membrane-associating domain DUF4161 PF13722.1 EMC77630.1 - 0.45 10.8 6.5 0.57 10.4 4.5 1.3 1 0 0 1 1 1 0 C-terminal domain on CstA (DUF4161) Strabismus PF06638.6 EMC77630.1 - 0.62 8.3 5.2 0.7 8.1 3.6 1.0 1 0 0 1 1 1 0 Strabismus protein dNK PF01712.14 EMC77631.1 - 2.4e-26 92.4 1.0 2.7e-26 92.2 0.7 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 EMC77631.1 - 9.9e-05 22.6 0.3 0.00013 22.2 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC77631.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMC77631.1 - 0.002 17.5 0.1 0.0024 17.2 0.0 1.3 1 1 0 1 1 1 1 Thymidylate kinase Cadherin PF00028.12 EMC77633.1 - 2.4e-69 229.6 10.1 2e-19 69.6 0.4 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC77633.1 - 3.8e-46 156.8 0.6 7.4e-46 155.8 0.4 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 EMC77633.1 - 0.0082 15.8 0.3 2.4 7.9 0.0 2.9 2 0 0 2 2 2 2 Cadherin prodomain like Rifin_STEVOR PF02009.11 EMC77633.1 - 0.035 13.7 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family Cadherin PF00028.12 EMC77635.1 - 6.2e-82 269.9 3.5 6.4e-19 68.0 0.0 5.5 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC77635.1 - 6.2e-58 195.0 0.3 1.4e-57 193.8 0.2 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC77635.1 - 0.00019 20.9 0.0 0.22 11.1 0.0 3.5 4 1 0 4 4 4 2 Cadherin-like ASFV_J13L PF05568.6 EMC77635.1 - 0.0049 16.4 0.0 0.0095 15.4 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF443 PF04276.7 EMC77635.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Trypsin PF00089.21 EMC77637.1 - 8.7e-17 61.4 0.2 9.5e-17 61.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin cNMP_binding PF00027.24 EMC77638.1 - 5.5e-37 125.4 0.0 1.1e-17 63.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Patatin PF01734.17 EMC77638.1 - 1.6e-22 80.4 0.1 3.3e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase TPP_enzyme_C PF02775.16 EMC77639.1 - 2.9e-20 72.4 0.0 4.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMC77639.1 - 6.1e-15 55.1 0.0 1.4e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CBM_21 PF03370.8 EMC77640.1 - 3.9e-34 117.0 0.6 8.6e-34 115.9 0.2 1.6 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EMC77640.1 - 0.039 14.0 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Ldl_recept_a PF00057.13 EMC77641.1 - 4e-42 141.8 98.7 5.4e-10 38.9 4.7 6.9 6 0 0 6 6 6 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 EMC77641.1 - 5.3e-27 93.8 1.3 1.4e-09 38.1 0.0 5.7 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 EMC77641.1 - 5.7e-11 42.3 24.4 5.4e-08 32.8 5.1 7.4 7 1 0 7 7 7 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 EMC77641.1 - 6.4e-08 32.4 2.8 6.4e-08 32.4 2.0 7.6 5 2 3 8 8 8 1 Calcium-binding EGF domain cEGF PF12662.2 EMC77641.1 - 3.7e-07 29.6 6.9 0.00015 21.3 0.4 4.9 6 0 0 6 6 6 2 Complement Clr-like EGF-like PMP22_Claudin PF00822.15 EMC77642.1 - 3e-15 56.2 0.0 3.8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC77642.1 - 1.3e-05 24.9 2.4 2e-05 24.3 1.2 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PIRT PF15099.1 EMC77642.1 - 0.00012 21.2 3.4 0.0018 17.5 0.8 2.4 2 0 0 2 2 2 1 Phosphoinositide-interacting protein family Clc-like PF07062.7 EMC77642.1 - 0.0035 16.6 0.6 0.0071 15.6 0.0 1.8 2 0 0 2 2 2 1 Clc-like L_HGMIC_fpl PF10242.4 EMC77642.1 - 0.0076 16.2 1.6 0.01 15.8 1.1 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein TauE PF01925.14 EMC77642.1 - 0.042 13.2 6.3 0.043 13.2 3.6 1.5 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF1418 PF07214.7 EMC77642.1 - 0.25 10.9 2.1 0.42 10.2 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1418) DUF2892 PF11127.3 EMC77642.1 - 2 8.2 13.0 0.11 12.3 2.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) DUF4131 PF13567.1 EMC77642.1 - 2.8 7.3 5.4 1.5 8.1 1.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PepSY_TM PF03929.11 EMC77642.1 - 3.5 8.2 16.7 3.4 8.2 0.1 3.6 3 0 0 3 3 3 0 PepSY-associated TM helix RnaseA PF00074.15 EMC77644.1 - 0.00016 21.9 0.1 0.00016 21.9 0.0 1.0 1 0 0 1 1 1 1 Pancreatic ribonuclease Ribosomal_S3Ae PF01015.13 EMC77645.1 - 1.7e-81 272.2 5.3 2e-81 272.0 3.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EMC77645.1 - 0.0044 16.3 0.1 0.018 14.3 0.0 2.1 1 1 1 2 2 2 1 Partial alpha/beta-hydrolase lipase region Isy1 PF06246.7 EMC77645.1 - 0.043 13.2 1.2 0.068 12.5 0.9 1.3 1 0 0 1 1 1 0 Isy1-like splicing family SpoVIF PF14069.1 EMC77645.1 - 0.059 13.1 3.3 0.092 12.4 1.5 1.9 2 0 0 2 2 2 0 Stage VI sporulation protein F RAI16-like PF10257.4 EMC77647.1 - 3.4e-100 335.4 11.9 4e-100 335.1 8.2 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TMEM154 PF15102.1 EMC77648.1 - 1.2e-35 122.3 1.7 1.7e-35 121.8 1.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 EMC77648.1 - 1.3e-06 28.3 0.1 2.6e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EMC77648.1 - 2.4e-05 24.1 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 EMC77648.1 - 0.0024 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CcmH PF03918.9 EMC77648.1 - 0.005 15.8 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein AMA-1 PF02430.10 EMC77648.1 - 0.0078 15.1 0.1 0.013 14.3 0.0 1.3 1 1 0 1 1 1 1 Apical membrane antigen 1 DUF3609 PF12259.3 EMC77648.1 - 0.0089 14.7 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) O-ag_pol_Wzy PF14296.1 EMC77648.1 - 0.012 14.2 0.0 0.014 14.0 0.0 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF4064 PF13273.1 EMC77648.1 - 0.014 15.4 0.2 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.1 EMC77648.1 - 0.018 15.4 0.2 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 EMC77648.1 - 0.019 14.6 0.2 0.026 14.1 0.1 1.3 1 1 0 1 1 1 0 CD34/Podocalyxin family SIT PF15330.1 EMC77648.1 - 0.021 14.9 0.4 0.031 14.4 0.3 1.5 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Afaf PF15339.1 EMC77648.1 - 0.029 13.9 0.1 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor YajC PF02699.10 EMC77648.1 - 0.03 13.9 0.2 0.064 12.9 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit DUF843 PF05814.6 EMC77648.1 - 0.031 14.0 0.2 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF3377 PF11857.3 EMC77648.1 - 0.036 13.6 1.2 0.054 13.1 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) LRRC37AB_C PF14914.1 EMC77648.1 - 0.038 13.4 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF3413 PF11893.3 EMC77648.1 - 0.051 12.4 0.1 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) ODV-E18 PF10717.4 EMC77648.1 - 0.051 13.0 1.8 0.064 12.6 0.6 1.7 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CCSMST1 PF15013.1 EMC77648.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family TctB PF07331.6 EMC77648.1 - 0.068 12.8 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2207 PF09972.4 EMC77648.1 - 0.07 11.6 0.0 0.09 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BatD PF13584.1 EMC77648.1 - 0.073 11.6 0.0 0.092 11.3 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4446 PF14584.1 EMC77648.1 - 0.078 12.8 0.4 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) PspB PF06667.7 EMC77648.1 - 0.13 12.2 0.8 0.22 11.4 0.6 1.5 1 1 0 1 1 1 0 Phage shock protein B P12 PF12669.2 EMC77648.1 - 0.35 11.1 0.1 0.35 11.1 0.1 1.6 2 0 0 2 2 1 0 Virus attachment protein p12 family Arfaptin PF06456.8 EMC77649.1 - 2.6e-81 272.3 9.3 3.6e-81 271.8 6.5 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.13 EMC77649.1 - 0.003 17.1 10.6 0.0067 15.9 7.4 1.6 1 1 0 1 1 1 1 BAR domain NHL PF01436.16 EMC77650.1 - 2e-48 159.9 17.5 9.1e-10 37.9 0.1 6.5 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.14 EMC77650.1 - 1.3e-18 67.4 0.0 5.2e-18 65.4 0.0 2.1 1 0 0 1 1 1 1 Filamin/ABP280 repeat SGL PF08450.7 EMC77650.1 - 1.2e-11 44.4 3.3 5.6e-05 22.6 0.0 5.5 1 1 5 6 6 6 3 SMP-30/Gluconolaconase/LRE-like region zf-B_box PF00643.19 EMC77650.1 - 1.4e-10 40.8 3.2 1.4e-10 40.8 2.2 3.1 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_2 PF13923.1 EMC77650.1 - 2.4e-08 33.8 10.8 2.4e-08 33.8 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77650.1 - 4.3e-08 32.6 10.2 4.3e-08 32.6 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77650.1 - 1.2e-07 31.3 8.7 1.2e-07 31.3 6.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC77650.1 - 1.3e-07 31.3 10.2 1.3e-07 31.3 7.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC77650.1 - 2.1e-07 30.5 7.3 2.1e-07 30.5 5.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC77650.1 - 1.3e-06 28.0 5.8 1.8e-06 27.5 2.4 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC77650.1 - 6.1e-05 22.8 11.2 6.1e-05 22.8 7.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMC77650.1 - 0.0055 16.5 1.4 0.014 15.2 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SBBP PF06739.6 EMC77650.1 - 0.0063 16.2 1.7 0.41 10.4 0.2 3.4 4 0 0 4 4 4 1 Beta-propeller repeat Big_1 PF02369.11 EMC77650.1 - 0.023 14.6 0.4 0.099 12.5 0.3 2.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Ldl_recept_b PF00058.12 EMC77650.1 - 0.026 14.8 0.0 20 5.5 0.0 4.0 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B IBR PF01485.16 EMC77650.1 - 0.71 9.7 13.4 0.049 13.4 0.8 3.0 2 1 1 3 3 3 0 IBR domain VCBS PF13517.1 EMC77650.1 - 3 8.2 7.6 35 4.8 0.0 4.4 2 1 3 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING_6 PF14835.1 EMC77650.1 - 3.8 7.3 12.0 0.028 14.1 2.3 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Mnd1 PF03962.10 EMC77651.1 - 2e-72 242.7 8.3 2.3e-72 242.6 5.7 1.0 1 0 0 1 1 1 1 Mnd1 family DivIC PF04977.10 EMC77651.1 - 7.4e-06 25.3 11.1 0.001 18.4 1.2 3.3 1 1 2 3 3 3 2 Septum formation initiator Penicillinase_R PF03965.11 EMC77651.1 - 9.2e-05 22.5 0.5 0.00017 21.6 0.1 1.6 1 1 0 1 1 1 1 Penicillinase repressor TBPIP PF07106.8 EMC77651.1 - 0.00087 18.8 7.7 0.0013 18.3 5.4 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DsrD PF08679.6 EMC77651.1 - 0.023 14.6 3.1 0.14 12.2 0.2 2.6 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF342 PF03961.8 EMC77651.1 - 0.04 12.3 5.7 0.058 11.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TrmB PF01978.14 EMC77651.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB APG6 PF04111.7 EMC77651.1 - 0.073 12.0 9.2 0.098 11.6 6.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 EMC77651.1 - 0.097 12.3 5.0 2.9 7.5 0.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit S10_plectin PF03501.10 EMC77651.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain DUF4140 PF13600.1 EMC77651.1 - 0.12 12.8 2.6 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4226 PF10774.4 EMC77651.1 - 0.3 11.1 2.4 0.49 10.4 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) DUF904 PF06005.7 EMC77651.1 - 0.32 11.3 14.6 0.2 11.9 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) AAA_23 PF13476.1 EMC77651.1 - 0.62 10.3 10.7 1 9.6 7.4 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EMC77651.1 - 1.2 8.6 11.6 1.8 8.1 8.0 1.2 1 0 0 1 1 1 0 IncA protein FemAB PF02388.11 EMC77651.1 - 1.6 7.3 7.5 2.2 6.8 5.2 1.3 1 0 0 1 1 1 0 FemAB family DUF349 PF03993.7 EMC77651.1 - 2.9 8.1 17.8 9.3 6.4 6.3 2.9 1 1 2 3 3 3 0 Domain of Unknown Function (DUF349) DivIVA PF05103.8 EMC77651.1 - 5.2 7.1 12.6 2.8 7.9 2.2 2.4 1 1 1 2 2 2 0 DivIVA protein bZIP_2 PF07716.10 EMC77651.1 - 6.1 6.7 11.9 11 5.9 1.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Pox_A_type_inc PF04508.7 EMC77651.1 - 6.5 6.8 6.1 11 6.0 0.1 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3086 PF11285.3 EMC77651.1 - 9.7 4.9 8.6 4.6 5.9 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) DUF3651 PF12371.3 EMC77652.1 - 1.7e-06 27.9 10.1 3e-05 23.9 0.2 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3651) LRR_8 PF13855.1 EMC77653.1 - 1.6e-36 123.8 41.7 2.5e-14 52.7 5.9 7.7 5 2 1 7 7 7 5 Leucine rich repeat TIR PF01582.15 EMC77653.1 - 5.3e-34 116.6 0.4 9.7e-34 115.8 0.3 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 EMC77653.1 - 2e-29 100.6 50.1 1.6e-05 24.3 3.5 9.9 4 2 9 13 13 13 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77653.1 - 5.6e-16 56.1 38.9 0.093 12.8 0.2 13.0 11 1 1 12 12 12 6 Leucine Rich Repeat TIR_2 PF13676.1 EMC77653.1 - 1.3e-12 47.7 0.0 2.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 EMC77653.1 - 1.4e-07 30.8 38.4 4.2 7.7 0.3 11.8 10 2 2 12 12 12 4 Leucine Rich repeat LRR_7 PF13504.1 EMC77653.1 - 2e-07 30.0 36.1 2.3 8.7 0.4 12.4 12 1 1 13 13 13 2 Leucine rich repeat LRR_9 PF14580.1 EMC77653.1 - 2.1e-05 24.1 6.9 0.048 13.2 0.3 4.5 2 2 1 4 4 4 1 Leucine-rich repeat LRR_5 PF13306.1 EMC77653.1 - 0.0001 21.9 0.3 0.00083 19.0 0.0 2.6 2 2 0 2 2 2 1 Leucine rich repeats (6 copies) DUF1863 PF08937.6 EMC77653.1 - 0.006 16.6 0.1 0.04 13.9 0.1 2.3 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Fz PF01392.17 EMC77655.1 - 4.7e-33 114.0 4.3 9.7e-33 112.9 3.0 1.5 1 0 0 1 1 1 1 Fz domain NTR PF01759.16 EMC77655.1 - 1.6e-15 56.6 0.2 2.6e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Chlam_OMP6 PF03504.8 EMC77655.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 Cadherin PF00028.12 EMC77656.1 - 1.7e-94 310.2 8.9 9e-20 70.7 0.0 6.5 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 EMC77656.1 - 3.2e-08 33.0 0.0 5 6.7 0.0 6.8 7 0 0 7 7 7 4 Cadherin-like Cadherin PF00028.12 EMC77657.1 - 4.4e-11 42.8 0.0 7.6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Cadherin domain WD40 PF00400.27 EMC77658.1 - 1.2e-54 180.3 20.1 1.9e-11 43.3 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC77658.1 - 4.6e-06 25.6 0.1 0.35 9.5 0.0 3.3 1 1 2 3 3 3 3 Nup133 N terminal like BBS2_Mid PF14783.1 EMC77658.1 - 0.00033 20.3 0.1 3.2 7.5 0.0 4.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EMC77658.1 - 0.00037 18.7 5.6 0.095 10.8 1.3 3.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMC77658.1 - 0.062 12.7 1.4 3.1 7.1 1.0 2.6 1 1 0 1 1 1 0 PQQ-like domain Fibrinogen_C PF00147.13 EMC77659.1 - 1.8e-111 371.3 15.0 2.4e-111 370.9 10.4 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 EMC77659.1 - 1.1e-41 142.3 3.5 1.5e-41 141.9 2.4 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1465 PF07323.7 EMC77659.1 - 0.025 14.1 0.9 0.8 9.2 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1465) Bacillus_HBL PF05791.6 EMC77659.1 - 0.18 11.1 7.1 0.11 11.8 1.5 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fibrinogen_C PF00147.13 EMC77660.1 - 2.6e-85 285.7 4.0 2.9e-85 285.5 2.8 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 EMC77661.1 - 5.9e-44 149.7 3.4 5.9e-44 149.7 2.3 2.0 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family Cor1 PF04803.7 EMC77661.1 - 0.04 13.6 1.7 0.1 12.3 1.2 1.7 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region HCMV_UL139 PF12507.3 EMC77661.1 - 0.048 13.8 0.2 0.084 13.0 0.1 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein FliD_C PF07195.7 EMC77661.1 - 0.054 12.7 1.9 0.11 11.7 1.3 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus PilJ PF13675.1 EMC77661.1 - 0.25 11.6 2.5 0.25 11.6 0.3 1.9 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EMC77661.1 - 1.2 8.9 6.8 9.9 5.9 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ING PF12998.2 EMC77661.1 - 6.8 7.0 9.1 5.8 7.2 0.8 2.5 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fibrinogen_C PF00147.13 EMC77662.1 - 1.2e-94 316.3 8.9 1.6e-94 315.9 6.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 EMC77662.1 - 8.9e-40 136.1 8.0 1.2e-39 135.6 5.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family OGFr_N PF04664.8 EMC77662.1 - 0.0097 15.2 0.4 0.016 14.4 0.3 1.4 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF2935 PF11155.3 EMC77662.1 - 0.017 15.2 2.5 0.069 13.2 0.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) DUF2360 PF10152.4 EMC77662.1 - 0.018 15.3 0.6 0.043 14.0 0.0 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) EzrA PF06160.7 EMC77662.1 - 0.047 11.8 3.5 0.072 11.2 2.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 EMC77662.1 - 0.14 10.7 4.8 0.2 10.2 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EMC77662.1 - 0.38 10.5 3.8 0.13 12.0 0.6 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lzipper-MIP1 PF14389.1 EMC77662.1 - 2.1 8.5 6.6 1.2 9.3 1.3 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1446 PF07287.6 EMC77663.1 - 3.8e-103 344.7 0.0 4.2e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) RRM_1 PF00076.17 EMC77664.1 - 1e-36 124.3 2.4 9.3e-14 50.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77664.1 - 1.3e-29 101.9 1.0 6.7e-10 38.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 EMC77664.1 - 7.9e-25 86.9 0.1 2.1e-24 85.5 0.0 1.8 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_5 PF13893.1 EMC77664.1 - 1e-17 63.7 0.9 7.3e-06 25.7 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC77664.1 - 0.003 17.2 0.1 0.56 10.0 0.0 3.2 1 1 2 3 3 3 1 Limkain b1 7tm_1 PF00001.16 EMC77665.1 - 1.4e-53 181.6 14.6 1.9e-53 181.2 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77665.1 - 4.3e-15 55.5 13.4 6e-15 55.1 9.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC77665.1 - 0.00029 20.0 8.7 0.00029 20.0 6.0 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4131 PF13567.1 EMC77665.1 - 0.056 12.8 0.1 0.056 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4207 PF13904.1 EMC77666.1 - 0.0034 16.7 53.1 0.0034 16.7 36.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4207) TolB_N PF04052.8 EMC77666.1 - 5.2 7.2 8.3 1.6 8.8 0.4 3.1 1 1 3 4 4 4 0 TolB amino-terminal domain AF-4 PF05110.8 EMC77667.1 - 4.6e-89 299.7 27.0 7.9e-60 202.9 13.7 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein Macoilin PF09726.4 EMC77667.1 - 1 7.5 15.7 1.3 7.2 10.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FXR1P_C PF12235.3 EMC77668.1 - 8.4e-56 188.3 25.3 1.7e-55 187.4 17.5 1.5 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal KH_1 PF00013.24 EMC77668.1 - 1.5e-18 66.1 0.8 2.1e-08 33.6 0.9 2.6 2 0 0 2 2 2 2 KH domain Agenet PF05641.7 EMC77668.1 - 6.6e-09 35.8 0.6 1.3e-08 34.8 0.4 1.6 1 0 0 1 1 1 1 Agenet domain KH_3 PF13014.1 EMC77668.1 - 4e-06 26.3 0.7 5.4e-05 22.7 0.3 2.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 EMC77668.1 - 0.00041 19.8 0.6 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EMC77668.1 - 0.016 14.8 1.1 1.6 8.4 0.2 3.3 2 1 1 3 3 3 0 KH domain HSF_DNA-bind PF00447.12 EMC77669.1 - 4.1e-07 30.1 0.0 4.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding LRR_8 PF13855.1 EMC77670.1 - 6.2e-46 153.9 50.9 3.3e-16 58.7 0.8 6.8 2 2 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EMC77670.1 - 1.9e-19 68.8 44.6 0.00071 19.1 0.3 7.8 2 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC77670.1 - 8.1e-18 64.3 0.0 6.8e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC77670.1 - 7.4e-16 55.7 35.4 0.14 12.2 0.3 12.8 12 0 0 12 12 12 5 Leucine Rich Repeat LRRNT PF01462.13 EMC77670.1 - 0.0086 15.5 2.1 0.0086 15.5 1.4 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Sialidase PF02973.11 EMC77670.1 - 0.039 12.9 0.2 0.13 11.2 0.0 2.0 2 0 0 2 2 2 0 Sialidase, N-terminal domain IncA PF04156.9 EMC77670.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 IncA protein Haemagg_act PF05860.8 EMC77670.1 - 0.098 12.4 0.3 8.7 6.1 0.0 2.3 2 0 0 2 2 2 0 haemagglutination activity domain LRR_9 PF14580.1 EMC77670.1 - 0.39 10.2 9.0 6.4 6.2 0.1 3.6 2 2 2 4 4 4 0 Leucine-rich repeat LRR_8 PF13855.1 EMC77671.1 - 9.1e-56 185.4 65.3 1.3e-15 56.8 2.8 6.2 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 EMC77671.1 - 8.2e-31 105.1 34.0 4.2e-10 39.0 0.1 7.8 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC77671.1 - 7.1e-17 61.3 0.4 7.6e-08 32.1 0.6 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC77671.1 - 5.1e-13 47.1 39.4 0.043 13.8 0.0 12.8 13 0 0 13 13 13 5 Leucine Rich Repeat LRRNT PF01462.13 EMC77671.1 - 0.00032 20.0 4.1 0.00032 20.0 2.8 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EMC77671.1 - 0.0011 18.8 39.5 1.1 9.7 0.2 10.8 11 0 0 11 11 11 3 Leucine rich repeat LRR_9 PF14580.1 EMC77671.1 - 0.014 14.9 11.3 1.9 8.0 0.9 3.9 2 2 2 4 4 4 0 Leucine-rich repeat SOXp PF12336.3 EMC77672.1 - 1.9e-28 98.8 2.2 1.9e-28 98.8 1.5 3.6 3 1 1 4 4 4 2 SOX transcription factor HMG_box PF00505.14 EMC77672.1 - 1.4e-27 95.7 4.6 1.4e-27 95.7 3.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC77672.1 - 6.2e-12 45.7 4.0 1e-11 45.0 2.8 1.3 1 0 0 1 1 1 1 HMG-box domain Neur_chan_memb PF02932.11 EMC77674.1 - 2.1e-56 191.4 0.0 3.3e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC77674.1 - 4.5e-40 137.0 0.1 6.4e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 EMC77675.1 - 9.8e-50 168.6 0.0 1.4e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC77675.1 - 2.2e-47 161.9 4.0 3.2e-38 131.9 2.2 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC77676.1 - 2.1e-51 174.1 1.1 3e-51 173.6 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC77676.1 - 2e-44 152.2 10.0 1.1e-39 136.8 2.9 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Collagen PF01391.13 EMC77677.1 - 3.3e-27 93.7 61.7 1.5e+04 -6.3 42.8 4.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) RPEL PF02755.10 EMC77678.1 - 1.2e-20 72.1 6.8 4.3e-07 29.0 0.0 3.5 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.22 EMC77678.1 - 1e-09 37.6 0.1 1e-09 37.6 0.1 2.2 3 0 0 3 3 3 1 SAP domain A_deaminase_N PF08451.6 EMC77678.1 - 0.011 15.7 0.4 0.047 13.7 0.2 2.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal FlxA PF14282.1 EMC77678.1 - 9.8 6.1 34.9 1.6 8.6 13.0 3.2 2 0 0 2 2 2 0 FlxA-like protein LRAT PF04970.8 EMC77679.1 - 2.7e-10 40.2 0.0 4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 EMC77679.1 - 0.0056 16.4 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C97 PF05903.9 EMC77679.1 - 0.045 13.5 0.5 0.075 12.8 0.4 1.5 1 1 0 1 1 1 0 PPPDE putative peptidase domain LRAT PF04970.8 EMC77680.1 - 1.2e-08 34.9 0.3 5.6e-08 32.7 0.2 1.9 1 1 0 1 1 1 1 Lecithin retinol acyltransferase DUF830 PF05708.7 EMC77680.1 - 0.0079 16.1 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 Orthopoxvirus protein of unknown function (DUF830) LRAT PF04970.8 EMC77681.1 - 5.3e-10 39.3 1.6 2.5e-09 37.1 1.1 1.8 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 EMC77681.1 - 0.016 14.9 0.1 0.05 13.4 0.0 1.8 2 0 0 2 2 2 0 NlpC/P60 family DUF1287 PF06940.6 EMC77681.1 - 0.054 12.9 0.1 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1287) Adaptin_N PF01602.15 EMC77682.1 - 6.7e-29 100.6 0.0 8.4e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region zf-C3HC4_3 PF13920.1 EMC77683.1 - 2.1e-09 36.9 6.6 2.1e-09 36.9 4.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77683.1 - 4e-09 36.1 10.7 2.2e-08 33.7 7.0 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC77683.1 - 9.5e-09 34.7 9.7 3.4e-08 33.0 6.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC77683.1 - 7.1e-08 32.3 9.5 7.1e-08 32.3 6.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC77683.1 - 1.8e-07 31.1 5.9 1.8e-07 31.1 4.1 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC77683.1 - 1.2e-05 24.8 9.0 2.8e-05 23.7 5.6 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC77683.1 - 0.0027 17.3 7.0 0.0066 16.1 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMC77683.1 - 0.0027 17.5 4.4 0.0027 17.5 3.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC77683.1 - 0.041 13.7 9.5 0.14 12.0 6.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC77683.1 - 0.092 12.3 11.0 0.84 9.2 6.7 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PWI PF01480.12 EMC77683.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 PWI domain Zip PF02535.17 EMC77684.1 - 1.1 8.2 1.6 1.7 7.5 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sulfatase PF00884.18 EMC77685.1 - 1.8e-50 171.8 0.3 3.6e-50 170.9 0.0 1.6 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EMC77685.1 - 1.6e-10 40.8 0.0 2.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMC77685.1 - 0.006 15.0 0.0 0.038 12.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Tmemb_185A PF10269.4 EMC77686.1 - 1.6e-69 234.1 27.2 1.6e-69 234.1 18.8 1.6 2 0 0 2 2 2 1 Transmembrane Fragile-X-F protein ASCH PF04266.9 EMC77687.1 - 0.028 14.7 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 ASCH domain TRCF PF03461.10 EMC77687.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TRCF domain Met_10 PF02475.11 EMC77688.1 - 2.1e-27 96.0 0.0 2.7e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EMC77688.1 - 2.7e-07 30.6 0.2 6.8e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC77688.1 - 0.00017 20.9 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC77688.1 - 0.0014 19.1 0.0 0.004 17.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC77688.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EMC77688.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NAD_binding_6 PF08030.7 EMC77689.1 - 4.9e-31 107.7 0.0 1.1e-30 106.6 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMC77689.1 - 3.3e-23 81.5 0.0 5.8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMC77689.1 - 4e-23 81.8 5.5 1e-22 80.5 3.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMC77689.1 - 8.1e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMC77689.1 - 0.00074 20.0 0.0 0.0051 17.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Phage_hub_GP28 PF11110.3 EMC77689.1 - 0.025 14.2 0.1 0.059 13.0 0.1 1.6 1 0 0 1 1 1 0 Baseplate hub distal subunit Tic20 PF09685.5 EMC77689.1 - 1.3 8.9 8.9 0.84 9.6 2.1 2.8 2 2 0 2 2 2 0 Tic20-like protein XK-related PF09815.4 EMC77690.1 - 1.6e-66 224.6 15.6 2.9e-66 223.7 10.8 1.4 1 1 0 1 1 1 1 XK-related protein HAD PF12710.2 EMC77691.1 - 7e-19 68.7 0.1 1.8e-18 67.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC77691.1 - 7.4e-17 61.1 0.0 7.4e-17 61.1 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EMC77691.1 - 2.1e-12 46.8 0.0 8.4e-12 44.8 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EMC77691.1 - 3.4e-11 43.9 0.9 4e-07 30.6 0.3 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC77691.1 - 0.0078 15.8 0.0 0.5 9.8 0.0 3.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RhoGEF PF00621.15 EMC77692.1 - 3.5e-36 124.7 0.3 3.5e-36 124.7 0.2 3.0 3 0 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 EMC77692.1 - 8.5e-16 58.1 0.0 2.9e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.24 EMC77692.1 - 2.8e-05 24.2 0.1 6.7e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 PH domain Spectrin PF00435.16 EMC77692.1 - 0.0069 16.6 1.1 0.0069 16.6 0.8 4.9 5 1 0 5 5 5 2 Spectrin repeat Crp PF00325.15 EMC77692.1 - 0.14 11.6 0.1 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF948 PF06103.6 EMC77692.1 - 0.17 11.7 0.9 3.7 7.4 0.1 3.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tubulin PF00091.20 EMC77693.1 - 3.7e-55 187.0 0.0 6.4e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC77693.1 - 9.5e-50 167.8 0.1 1.6e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC77693.1 - 0.0069 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF1648 PF07853.6 EMC77694.1 - 0.0067 15.9 4.3 10 5.7 0.1 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF1648) Antimicrobial10 PF08105.6 EMC77694.1 - 3.8 7.2 6.2 9.8 5.8 0.1 3.1 3 0 0 3 3 3 0 Metchnikowin family Mst1_SARAH PF11629.3 EMC77695.1 - 5.2e-05 22.9 7.3 93 2.9 0.0 7.5 4 1 5 9 9 9 0 C terminal SARAH domain of Mst1 WXG100 PF06013.7 EMC77695.1 - 0.0017 18.2 0.0 54 3.8 0.0 4.1 1 1 4 5 5 5 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 EMC77695.1 - 0.11 12.3 0.5 9 6.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prolamin_like PF05617.6 EMC77695.1 - 0.16 12.1 2.9 66 3.7 0.0 3.9 1 1 3 4 4 4 0 Prolamin-like Squash PF00299.13 EMC77696.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Squash family serine protease inhibitor SEA PF01390.15 EMC77697.1 - 1.5e-46 156.4 1.6 4.5e-16 58.4 0.0 3.1 3 0 0 3 3 3 3 SEA domain Peptidase_S64 PF08192.6 EMC77697.1 - 2.2e-05 23.0 0.5 0.082 11.2 0.0 2.7 3 0 0 3 3 3 2 Peptidase family S64 DUF2205 PF10224.4 EMC77697.1 - 3.5e-05 23.2 0.0 1.3 8.6 0.0 3.5 3 0 0 3 3 3 2 Predicted coiled-coil protein (DUF2205) Pkinase_Tyr PF07714.12 EMC77698.1 - 5.4e-92 307.5 1.4 7.2e-92 307.1 1.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77698.1 - 1.7e-47 161.7 0.3 2.7e-47 161.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC77698.1 - 1.7e-40 136.6 0.2 1.1e-21 76.4 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Kdo PF06293.9 EMC77698.1 - 0.088 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADAM_spacer1 PF05986.9 EMC77699.1 - 2.1e-35 121.0 0.0 3.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.14 EMC77699.1 - 3.6e-27 94.7 0.1 5.9e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 EMC77699.1 - 7.1e-26 91.0 0.2 1.9e-25 89.6 0.2 1.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 EMC77699.1 - 8.3e-17 61.0 88.8 1.4e-06 28.3 5.9 7.9 8 1 0 8 8 7 5 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 EMC77699.1 - 4.8e-13 49.4 0.1 1.1e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC77699.1 - 1.2e-11 45.1 0.0 2.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC77699.1 - 3.1e-11 43.6 0.2 5e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 EMC77699.1 - 1.2e-10 41.5 9.8 4.8e-10 39.5 6.8 2.2 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Reprolysin_4 PF13583.1 EMC77699.1 - 6.8e-09 35.5 0.1 1.2e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EMC77699.1 - 0.012 14.9 0.4 0.026 13.8 0.3 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EMC77699.1 - 0.11 12.2 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF1025 PF06262.6 EMC77699.1 - 0.15 11.8 0.1 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase zf-H2C2_5 PF13909.1 EMC77700.1 - 3.2e-05 23.8 1.4 5.8e-05 23.0 0.4 1.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EMC77700.1 - 0.089 13.1 0.2 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC77700.1 - 0.13 12.7 0.2 0.2 12.0 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type LRR_8 PF13855.1 EMC77701.1 - 4.4e-16 58.3 36.7 1.2e-08 34.5 4.4 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC77701.1 - 6.9e-15 54.2 21.8 2e-09 36.8 3.9 3.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EMC77701.1 - 1.6e-08 34.2 0.3 2.2e-08 33.8 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EMC77701.1 - 2.9e-07 29.5 11.5 0.19 12.0 0.2 5.5 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EMC77701.1 - 1.7e-06 27.4 11.9 0.0047 16.8 0.4 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 EMC77701.1 - 0.00011 21.7 15.1 0.017 15.0 0.3 4.9 5 1 0 5 5 5 3 Leucine Rich Repeat Ceramidase PF05875.7 EMC77702.1 - 2.4e-58 197.3 14.5 2.9e-58 197.0 10.1 1.0 1 0 0 1 1 1 1 Ceramidase AMP-binding PF00501.23 EMC77703.1 - 8.3e-82 274.7 0.0 1e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.5 EMC77703.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_5 PF13893.1 EMC77704.1 - 0.00034 20.4 0.0 0.0021 17.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC77704.1 - 0.0028 17.2 0.0 0.42 10.2 0.0 2.2 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77704.1 - 0.017 15.1 0.0 0.067 13.1 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EMC77705.1 - 1.2e-12 47.2 8.2 1.6e-12 46.9 5.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77705.1 - 9.2e-11 41.3 8.9 1.4e-10 40.8 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC77705.1 - 1.6e-10 40.4 8.2 2.3e-10 39.9 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC77705.1 - 4.4e-10 39.4 9.8 5.8e-10 39.0 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC77705.1 - 3.9e-08 33.2 8.5 9.5e-08 32.0 5.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC77705.1 - 8.6e-08 31.7 8.3 1.7e-07 30.8 5.8 1.5 1 1 1 2 2 2 2 zinc-RING finger domain zf-Apc11 PF12861.2 EMC77705.1 - 1.2e-06 28.2 4.1 1.7e-06 27.7 2.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC77705.1 - 2.1e-05 24.2 6.1 7e-05 22.6 4.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC77705.1 - 3.8e-05 23.3 7.2 0.00038 20.1 1.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EMC77705.1 - 0.00043 19.8 12.5 0.0015 18.0 3.4 2.1 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain TerY-C PF15616.1 EMC77705.1 - 0.0093 15.9 1.6 0.0094 15.8 1.1 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_6 PF14835.1 EMC77705.1 - 0.011 15.4 1.9 0.016 14.9 1.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-IS66 PF13005.2 EMC77705.1 - 0.02 14.8 2.3 1.9 8.5 0.3 2.8 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Rad50_zn_hook PF04423.9 EMC77705.1 - 0.026 13.9 1.5 3.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1644 PF07800.7 EMC77705.1 - 0.03 14.1 1.7 4.4 7.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zinc-ribbons_6 PF07191.7 EMC77705.1 - 0.11 12.2 7.6 0.52 10.1 5.1 1.9 1 1 0 1 1 1 0 zinc-ribbons Pellino PF04710.9 EMC77705.1 - 0.13 10.8 0.5 7.1 5.1 0.0 2.0 1 1 1 2 2 2 0 Pellino zf-Di19 PF05605.7 EMC77705.1 - 0.27 11.3 4.9 2.7 8.1 3.4 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.1 EMC77705.1 - 0.56 9.8 9.7 8.8 5.9 6.7 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 YdjO PF14169.1 EMC77705.1 - 0.67 9.4 8.0 1.1 8.8 1.9 2.4 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-Nse PF11789.3 EMC77705.1 - 0.94 9.0 6.2 1.6 8.3 4.2 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_4 PF07975.7 EMC77705.1 - 1.3 9.1 7.2 5.6 7.0 5.0 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain FdhE PF04216.7 EMC77705.1 - 1.3 8.6 6.8 1.9 8.1 4.7 1.3 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Opy2 PF09463.5 EMC77705.1 - 1.9 8.6 6.8 2.5 8.2 1.0 2.4 1 1 1 2 2 2 0 Opy2 protein DZR PF12773.2 EMC77705.1 - 2.1 8.2 7.9 7.6 6.4 5.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.9 EMC77705.1 - 6 6.4 8.5 26 4.4 5.8 2.0 2 1 0 2 2 1 0 P-11 zinc finger Zn-ribbon_8 PF09723.5 EMC77705.1 - 7 6.6 7.5 21 5.1 0.1 2.5 2 1 0 2 2 2 0 Zinc ribbon domain PAP2 PF01569.16 EMC77706.1 - 1.2e-14 54.1 1.3 1.2e-14 54.1 0.9 1.6 2 0 0 2 2 2 1 PAP2 superfamily Ribosomal_L50 PF10501.4 EMC77707.1 - 1.4e-22 79.7 0.3 2.2e-22 79.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal subunit 39S zf-C3HC4_3 PF13920.1 EMC77709.1 - 8.3e-06 25.3 11.6 1.4e-05 24.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77709.1 - 6e-05 22.6 14.6 0.00011 21.7 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC77709.1 - 0.00017 21.5 14.4 0.00029 20.8 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77709.1 - 0.00077 19.1 13.7 0.0036 17.0 9.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC77709.1 - 0.021 14.6 14.5 0.078 12.8 10.3 1.8 1 1 1 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 EMC77709.1 - 0.063 13.0 2.8 0.13 12.0 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMC77709.1 - 0.46 10.2 8.3 1.4 8.6 5.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EMC77709.1 - 0.49 10.2 4.8 0.9 9.4 3.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC77709.1 - 0.6 10.0 9.5 1.4 8.8 6.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Yae1_N PF09811.4 EMC77710.1 - 1.5e-12 46.7 48.2 1.5e+04 -9.7 33.4 4.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-C3HC4_3 PF13920.1 EMC77711.1 - 5.8e-11 41.8 7.8 5.8e-11 41.8 5.4 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77711.1 - 1.1e-09 37.7 8.3 1.1e-09 37.7 5.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77711.1 - 9.5e-09 34.9 9.7 9.5e-09 34.9 6.7 2.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC77711.1 - 5.9e-08 32.6 9.1 5.9e-08 32.6 6.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC77711.1 - 5.5e-07 29.5 8.0 5.5e-07 29.5 5.5 2.5 1 1 1 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC77711.1 - 2.8e-05 23.7 4.3 0.0001 21.9 1.0 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC77711.1 - 9.1e-05 22.1 9.3 9.1e-05 22.1 6.4 3.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC77711.1 - 0.00031 20.5 6.7 0.00031 20.5 4.7 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC77711.1 - 0.0018 18.0 8.3 0.0018 18.0 5.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC77711.1 - 0.0029 17.1 12.0 0.02 14.4 3.3 2.9 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EMC77713.1 - 1e-09 37.8 5.9 1e-09 37.8 4.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77713.1 - 1.2e-08 34.5 9.8 1.2e-08 34.5 6.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC77713.1 - 1.5e-08 34.1 8.3 1.5e-08 34.1 5.7 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC77713.1 - 3.8e-07 30.1 6.6 3.8e-07 30.1 4.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC77713.1 - 4.6e-07 29.7 9.9 4.6e-07 29.7 6.8 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77713.1 - 2.2e-05 24.0 6.7 2.2e-05 24.0 4.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC77713.1 - 0.00016 21.4 4.4 0.00048 19.9 3.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EMC77713.1 - 0.011 15.1 0.7 0.22 11.0 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-MIZ PF02891.15 EMC77713.1 - 0.047 13.2 8.8 0.25 10.8 0.2 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Rubredoxin PF00301.15 EMC77713.1 - 0.14 12.0 0.2 0.14 12.0 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin zf-RING_4 PF14570.1 EMC77713.1 - 0.19 11.3 10.3 1.4 8.6 7.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMC77713.1 - 1.3 8.7 7.6 2.9 7.6 5.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Apt1 PF10351.4 EMC77713.1 - 4.4 6.0 10.4 6.3 5.5 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_viral_N PF00242.12 EMC77713.1 - 5 6.0 13.7 8 5.3 9.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain GEMIN8 PF15348.1 EMC77714.1 - 9e-76 254.5 16.5 1e-75 254.3 11.4 1.0 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Myelin_PLP PF01275.14 EMC77715.1 - 2.9e-125 416.4 21.0 3.3e-125 416.2 14.5 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF1049 PF06305.6 EMC77715.1 - 0.0094 15.4 2.3 0.055 12.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1049) PspB PF06667.7 EMC77715.1 - 0.017 15.0 1.4 0.018 15.0 0.0 1.7 2 0 0 2 2 2 0 Phage shock protein B FA_desaturase PF00487.19 EMC77715.1 - 0.031 13.6 2.6 0.02 14.3 0.8 1.5 1 1 0 1 1 1 0 Fatty acid desaturase FOP_dimer PF09398.5 EMC77716.1 - 0.00018 21.4 1.4 0.26 11.2 0.0 4.3 3 0 0 3 3 3 1 FOP N terminal dimerisation domain LisH PF08513.6 EMC77716.1 - 0.0025 17.5 0.0 0.0069 16.1 0.0 1.8 1 0 0 1 1 1 1 LisH Sedlin_N PF04628.8 EMC77717.1 - 1e-44 151.6 0.7 1.1e-44 151.4 0.5 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EMC77717.1 - 7.5e-09 35.4 0.2 9.7e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family Pex14_N PF04695.8 EMC77717.1 - 0.044 13.8 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ras PF00071.17 EMC77718.1 - 3.1e-57 192.4 0.0 3.7e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC77718.1 - 7.3e-18 65.1 0.0 1.1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC77718.1 - 9.9e-12 44.4 0.0 1.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC77718.1 - 6.8e-06 25.3 0.0 9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC77718.1 - 7.8e-06 25.8 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC77718.1 - 0.0032 16.6 0.1 0.0082 15.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMC77718.1 - 0.0037 16.7 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMC77718.1 - 0.0054 16.2 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EMC77718.1 - 0.0082 15.7 0.2 0.058 12.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EMC77718.1 - 0.038 13.9 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EMC77718.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMC77718.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EMC77718.1 - 0.13 11.9 0.3 0.52 9.9 0.0 1.9 2 1 0 2 2 2 0 Archaeal ATPase DUF3168 PF11367.3 EMC77718.1 - 0.17 12.0 0.7 4.8 7.3 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3168) TFIIS_M PF07500.9 EMC77719.1 - 1.7e-30 105.4 2.1 1.7e-30 105.4 1.5 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 EMC77719.1 - 4.8e-10 38.7 0.3 1.1e-09 37.6 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 EMC77719.1 - 0.0059 16.2 5.7 0.0063 16.1 0.2 2.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) MutS_III PF05192.13 EMC77719.1 - 0.059 13.1 7.3 0.18 11.5 5.1 1.9 1 1 0 1 1 1 0 MutS domain III Myb_DNA-bind_4 PF13837.1 EMC77719.1 - 0.52 10.4 9.3 2.5 8.2 1.6 3.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain MAM PF00629.18 EMC77720.1 - 1.8e-27 96.1 0.0 4e-27 94.9 0.0 1.5 1 1 0 1 1 1 1 MAM domain zf-C3HC4_3 PF13920.1 EMC77721.1 - 3.2e-10 39.4 6.6 6.5e-10 38.5 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77721.1 - 4.3e-09 35.8 9.7 1.1e-08 34.5 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC77721.1 - 7.3e-09 35.3 10.1 7.3e-09 35.3 7.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC77721.1 - 9.5e-09 35.1 9.5 2.4e-08 33.8 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC77721.1 - 2e-07 31.0 7.8 5e-07 29.7 5.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC77721.1 - 3.3e-06 26.7 7.9 8.3e-06 25.4 5.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC77721.1 - 0.00066 19.3 6.8 0.0018 17.9 4.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMC77721.1 - 0.00074 19.3 4.7 0.0016 18.2 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC77721.1 - 0.0031 17.3 7.3 0.0091 15.8 5.0 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING MRI PF15325.1 EMC77721.1 - 0.028 15.4 0.5 0.028 15.4 0.3 2.9 3 0 0 3 3 3 0 Modulator of retrovirus infection zf-RING_4 PF14570.1 EMC77721.1 - 0.036 13.6 9.9 0.21 11.2 6.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EMC77721.1 - 0.49 9.9 5.5 0.97 8.9 3.8 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 EMC77721.1 - 0.55 10.0 3.8 1.5 8.6 2.6 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Keratin PF02422.11 EMC77722.1 - 8.1e-43 144.3 12.9 9.5e-43 144.1 8.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77723.1 - 3.5e-42 142.3 15.7 3.8e-42 142.2 10.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77726.1 - 1.9e-28 98.3 13.1 2.1e-28 98.1 9.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77728.1 - 1.3e-39 134.1 15.6 1.4e-39 134.0 10.8 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77729.1 - 3.4e-42 142.3 12.4 4e-42 142.1 8.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77730.1 - 3.6e-41 139.0 14.8 4e-41 138.9 10.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77732.1 - 1.7e-42 143.3 12.6 1.9e-42 143.1 8.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77733.1 - 8.7e-44 147.4 11.0 1e-43 147.2 7.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77735.1 - 7.9e-43 144.4 10.9 9.2e-43 144.1 7.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC77736.1 - 5e-41 138.6 11.3 5.9e-41 138.4 7.8 1.0 1 0 0 1 1 1 1 Keratin GTP_EFTU PF00009.22 EMC77737.1 - 4.3e-56 189.3 0.0 1.7e-55 187.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EMC77737.1 - 2.4e-17 62.5 0.0 9.2e-17 60.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EMC77737.1 - 2.9e-09 36.6 0.2 1.1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EMC77737.1 - 5.9e-09 35.9 0.0 2e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EMC77737.1 - 0.00019 20.9 0.2 0.0057 16.2 0.0 3.1 2 1 0 2 2 2 1 Elongation factor G, domain IV Miro PF08477.8 EMC77737.1 - 0.045 14.2 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein TMC PF07810.8 EMC77739.1 - 6.4e-42 142.4 2.3 6.4e-42 142.4 1.6 2.4 2 0 0 2 2 2 1 TMC domain START PF01852.14 EMC77740.1 - 2.7e-18 66.0 0.0 3.3e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 START domain PDZ PF00595.19 EMC77741.1 - 7.8e-24 83.6 1.4 5e-13 49.0 0.2 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC77741.1 - 5.8e-07 29.3 5.2 0.00023 20.9 0.2 3.2 3 0 0 3 3 3 2 PDZ domain Mesd PF10185.4 EMC77744.1 - 1.1e-68 229.8 0.8 1.5e-68 229.4 0.6 1.2 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor PSII_BNR PF14870.1 EMC77744.1 - 0.074 12.0 0.0 0.23 10.3 0.0 1.6 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 Beta_helix PF13229.1 EMC77745.1 - 0.0013 18.4 2.5 0.84 9.3 0.0 3.4 3 1 1 4 4 4 2 Right handed beta helix region Swi5 PF07061.6 EMC77746.1 - 1.2e-21 76.3 0.4 1.2e-21 76.2 0.3 1.0 1 0 0 1 1 1 1 Swi5 DUF1192 PF06698.6 EMC77746.1 - 0.057 13.2 0.3 0.077 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) GOLGA2L5 PF15070.1 EMC77747.1 - 9.5e-292 969.0 82.5 9.5e-292 969.0 57.2 2.3 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 DivIVA PF05103.8 EMC77747.1 - 0.0088 16.1 2.9 0.0088 16.1 2.0 10.4 2 1 8 10 10 10 1 DivIVA protein ADP_ribosyl_GH PF03747.9 EMC77747.1 - 0.12 12.1 0.0 0.73 9.5 0.0 2.4 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase IncA PF04156.9 EMC77747.1 - 1.3 8.5 170.7 0.061 12.9 16.6 8.1 3 2 5 8 8 8 0 IncA protein Dynamin_M PF01031.15 EMC77748.1 - 1.1e-101 339.5 6.1 1.1e-101 339.5 4.2 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EMC77748.1 - 7.6e-42 142.9 0.1 2.4e-41 141.3 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EMC77748.1 - 9e-27 92.8 2.5 2.3e-26 91.5 1.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 EMC77748.1 - 5.8e-11 42.5 0.7 1.2e-10 41.4 0.5 1.5 1 0 0 1 1 1 1 PH domain Ldh_1_N PF00056.18 EMC77748.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RILP PF11461.3 EMC77748.1 - 0.19 11.9 2.1 0.44 10.7 0.1 2.5 2 0 0 2 2 2 0 Rab interacting lysosomal protein DUF605 PF04652.11 EMC77748.1 - 3.7 6.8 6.7 5.2 6.3 4.6 1.2 1 0 0 1 1 1 0 Vta1 like zf-C2H2_jaz PF12171.3 EMC77749.1 - 7.8e-06 25.8 28.6 0.00014 21.8 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC77749.1 - 2.2e-05 24.5 28.5 0.0014 18.7 4.7 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC77749.1 - 0.16 12.1 24.1 0.042 13.9 1.3 3.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DNAPolymera_Pol PF11590.3 EMC77749.1 - 0.34 10.6 2.9 4.1 7.1 0.4 2.9 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol AKAP95 PF04988.7 EMC77749.1 - 1.5 8.6 17.0 1.8 8.3 8.4 2.5 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) UPF0184 PF03670.8 EMC77750.1 - 7.2e-26 90.1 1.8 8.1e-26 90.0 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) EzrA PF06160.7 EMC77750.1 - 0.02 13.1 1.1 0.02 13.0 0.8 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ATP-synt_D PF01813.12 EMC77750.1 - 0.045 13.3 0.1 0.046 13.2 0.1 1.0 1 0 0 1 1 1 0 ATP synthase subunit D FlgN PF05130.7 EMC77750.1 - 0.065 13.4 2.9 0.071 13.3 2.0 1.0 1 0 0 1 1 1 0 FlgN protein IncA PF04156.9 EMC77750.1 - 0.12 11.9 3.6 0.13 11.8 2.5 1.1 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 EMC77750.1 - 0.14 12.0 0.1 0.16 11.8 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF904 PF06005.7 EMC77750.1 - 0.74 10.1 5.3 1.3 9.3 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) GST_C_3 PF14497.1 EMC77751.1 - 1.5e-17 63.8 0.2 2.4e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC77751.1 - 1.7e-14 53.7 0.4 1.7e-13 50.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EMC77751.1 - 3.1e-11 43.1 0.1 7.1e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 EMC77751.1 - 4.7e-09 36.1 0.0 1.6e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC77751.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC77751.1 - 7.4e-05 22.6 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC77751.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 EMC77751.1 - 0.045 13.8 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 ArsC family SNARE_assoc PF09335.6 EMC77751.1 - 0.11 12.6 0.1 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 SNARE associated Golgi protein AAA_13 PF13166.1 EMC77752.1 - 0.00014 20.4 23.7 0.00014 20.4 16.4 4.0 1 1 2 3 3 3 1 AAA domain Tropomyosin PF00261.15 EMC77752.1 - 0.0034 16.4 39.1 0.0034 16.4 27.1 5.8 1 1 5 6 6 6 2 Tropomyosin GLE1 PF07817.8 EMC77753.1 - 6.1e-95 316.9 0.0 6.1e-95 316.9 0.0 2.8 2 1 0 3 3 3 1 GLE1-like protein NatB_MDM20 PF09797.4 EMC77753.1 - 0.0094 14.7 5.1 0.02 13.6 3.6 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit WD40 PF00400.27 EMC77754.1 - 6.4e-21 73.4 12.3 8e-05 22.3 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Spore_GerAC PF05504.6 EMC77754.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal NAP PF00956.13 EMC77755.1 - 2.4e-59 200.4 7.7 2.4e-59 200.4 5.4 2.2 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.7 EMC77755.1 - 0.00077 19.0 1.4 0.0016 17.9 1.0 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF904 PF06005.7 EMC77755.1 - 0.0064 16.7 2.1 0.014 15.6 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Mst1_SARAH PF11629.3 EMC77755.1 - 0.016 15.0 0.8 0.042 13.6 0.5 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 ACCA PF03255.9 EMC77755.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pkinase PF00069.20 EMC77756.1 - 3e-64 216.6 0.0 7.3e-64 215.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain HR1 PF02185.11 EMC77756.1 - 1.7e-45 152.5 30.4 7.3e-17 60.8 4.2 3.3 3 0 0 3 3 3 3 Hr1 repeat Pkinase_Tyr PF07714.12 EMC77756.1 - 9.5e-35 119.9 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMC77756.1 - 5.8e-09 36.3 0.6 1.2e-08 35.2 0.4 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Uds1 PF15456.1 EMC77756.1 - 1.8e-06 27.9 19.8 0.00057 19.8 0.9 3.3 3 0 0 3 3 3 3 Up-regulated During Septation Kinase-like PF14531.1 EMC77756.1 - 5.4e-05 22.2 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF2779 PF11074.3 EMC77756.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) DUF3416 PF11896.3 EMC77756.1 - 0.47 10.3 10.0 0.2 11.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3416) zf-DHHC PF01529.15 EMC77757.1 - 3.9e-38 130.5 7.9 4.8e-38 130.2 5.5 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2569 PF10754.4 EMC77757.1 - 0.0057 16.8 3.5 0.055 13.6 2.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) Pico_P2B PF01552.12 EMC77757.1 - 0.064 13.4 0.2 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Picornavirus 2B protein DUF3974 PF13120.1 EMC77757.1 - 0.66 9.8 4.3 0.16 11.8 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) DUF843 PF05814.6 EMC77757.1 - 2 8.2 6.6 0.13 12.0 0.4 2.1 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Baculo_11_kDa PF06143.6 EMC77757.1 - 3.5 7.0 9.1 0.11 11.9 1.2 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family Arm PF00514.18 EMC77758.1 - 1e-08 34.6 4.7 0.085 12.7 0.0 6.9 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat LRR_4 PF12799.2 EMC77758.1 - 0.0014 18.2 9.2 0.12 12.0 0.1 5.3 3 1 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC77758.1 - 0.0057 16.3 11.1 0.34 10.7 0.1 4.5 3 1 0 3 3 3 2 Leucine rich repeat RabGAP-TBC PF00566.13 EMC77759.1 - 3.5e-37 127.9 9.0 2.6e-34 118.5 2.3 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain TFIID_20kDa PF03847.8 EMC77759.1 - 0.021 15.1 0.5 0.053 13.8 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Methyltrn_RNA_3 PF02598.12 EMC77760.1 - 3e-97 325.4 0.0 4e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EMC77760.1 - 0.13 12.1 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 SpoU rRNA Methylase family Aminotran_1_2 PF00155.16 EMC77761.1 - 1.8e-56 191.6 0.0 2.1e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMC77761.1 - 0.00054 18.3 0.0 0.0011 17.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMC77761.1 - 0.0037 16.3 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMC77761.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3733 PF12534.3 EMC77762.1 - 2.3e-49 164.5 9.3 3e-29 100.0 0.8 2.6 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_4 PF12799.2 EMC77762.1 - 1.1e-41 139.8 53.2 1.9e-11 43.2 1.7 10.0 4 3 6 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC77762.1 - 9.3e-39 131.0 45.5 6.8e-14 51.3 3.2 6.8 2 2 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EMC77762.1 - 3.2e-12 44.6 45.3 0.00042 19.9 0.1 11.7 13 0 0 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC77762.1 - 2.4e-10 38.8 39.6 0.026 14.6 0.2 13.0 14 0 0 14 14 14 4 Leucine rich repeat PhyH PF05721.8 EMC77763.1 - 1.2e-63 214.9 0.0 1.5e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Nup188 PF10487.4 EMC77765.1 - 0 1161.0 0.1 0 1161.0 0.1 1.4 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 P3A PF08727.6 EMC77765.1 - 0.13 11.6 0.2 0.3 10.4 0.2 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like BAR PF03114.13 EMC77766.1 - 4.1e-62 209.7 1.6 5.3e-62 209.3 1.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EMC77766.1 - 1.6e-10 40.3 0.0 3.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC77766.1 - 1.5e-06 27.4 0.0 2.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC77766.1 - 5.6e-06 25.7 0.0 1.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 EMC77766.1 - 7.1e-06 25.1 0.2 1.2e-05 24.3 0.0 1.4 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2217 PF10265.4 EMC77767.1 - 4.4e-233 774.7 0.6 5.1e-233 774.5 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) PAP2 PF01569.16 EMC77768.1 - 5e-19 68.2 5.6 9.5e-19 67.3 3.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily Carn_acyltransf PF00755.15 EMC77769.1 - 1.9e-236 785.8 0.0 2.2e-236 785.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PTPA PF03095.10 EMC77770.1 - 4.5e-116 387.2 0.0 5e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_PK PF05891.7 EMC77771.1 - 1.3e-90 302.4 0.0 1.5e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 EMC77771.1 - 1.2e-09 38.4 0.0 2.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC77771.1 - 1e-08 35.5 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC77771.1 - 9.7e-08 32.5 0.0 1.5e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC77771.1 - 9.5e-07 29.1 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMC77771.1 - 4.4e-05 22.7 0.1 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMC77771.1 - 9.2e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC77771.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC77771.1 - 0.00015 21.0 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Dioxygenase_N PF04444.9 EMC77771.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus MTS PF05175.9 EMC77771.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EMC77771.1 - 0.074 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EMC77771.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Homeobox PF00046.24 EMC77772.1 - 1.8e-23 81.9 6.6 3.5e-23 80.9 4.6 1.5 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 EMC77772.1 - 8.7e-09 34.6 0.0 2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 EMC77772.1 - 0.00041 19.9 0.3 0.001 18.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain MAPEG PF01124.13 EMC77773.1 - 3.7e-19 68.5 0.5 5.9e-19 67.9 0.3 1.3 1 1 0 1 1 1 1 MAPEG family Torsin PF06309.6 EMC77774.1 - 1.2e-43 148.0 0.0 1.9e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Torsin AAA PF00004.24 EMC77774.1 - 0.00038 20.6 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EMC77774.1 - 0.0054 16.2 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EMC77774.1 - 0.0092 16.1 0.0 0.2 11.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 EMC77775.1 - 1.7e-47 160.4 0.4 2.8e-47 159.7 0.3 1.4 1 0 0 1 1 1 1 Torsin AAA PF00004.24 EMC77775.1 - 0.0053 16.9 0.0 0.0093 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC77775.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMC77775.1 - 0.046 13.8 0.0 6.4 6.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain Hep_59 PF07052.6 EMC77776.1 - 4.7e-17 62.2 5.5 4.7e-17 62.2 3.8 2.9 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 FCH PF00611.18 EMC77777.1 - 4.1e-21 74.9 4.0 4.1e-21 74.9 2.8 3.5 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMC77777.1 - 1.4e-10 40.5 0.1 2.9e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC77777.1 - 3.1e-10 39.2 0.1 6.8e-10 38.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC77777.1 - 2.1e-06 27.0 0.1 4.7e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC77777.1 - 4.1e-05 23.6 0.2 8.3e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain HR1 PF02185.11 EMC77777.1 - 8.1e-05 22.2 1.1 8.1e-05 22.2 0.7 3.4 4 1 0 4 4 4 1 Hr1 repeat Lzipper-MIP1 PF14389.1 EMC77777.1 - 0.0012 18.8 1.0 0.0044 17.0 0.7 2.0 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Uds1 PF15456.1 EMC77777.1 - 0.0026 17.7 0.4 0.0026 17.7 0.2 4.2 3 1 1 4 4 3 1 Up-regulated During Septation Rod_C PF10493.4 EMC77777.1 - 0.36 9.0 5.9 0.51 8.5 4.1 1.2 1 0 0 1 1 1 0 Rough deal protein C-terminal region Laminin_II PF06009.7 EMC77777.1 - 0.4 10.4 9.8 2.5 7.8 1.2 3.0 2 2 1 3 3 3 0 Laminin Domain II Spectrin PF00435.16 EMC77777.1 - 1.9 8.8 23.9 0.47 10.7 2.6 4.0 2 1 1 3 3 3 0 Spectrin repeat EF-hand_1 PF00036.27 EMC77778.1 - 7.8e-24 81.1 5.7 4.1e-07 28.8 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EMC77778.1 - 1.1e-23 83.0 0.8 1.1e-15 57.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC77778.1 - 2.4e-22 76.7 2.6 1.2e-05 24.8 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EMC77778.1 - 9.1e-18 62.7 4.2 4.4e-05 22.6 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EMC77778.1 - 4.3e-16 58.2 4.3 2.5e-05 23.8 0.2 3.7 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC77778.1 - 3.8e-05 23.6 0.6 0.0076 16.2 0.1 2.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC77778.1 - 0.00032 20.3 2.3 0.52 10.0 0.0 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC77778.1 - 0.00081 19.2 0.1 0.025 14.4 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain EF-hand_3 PF09069.6 EMC77778.1 - 0.011 15.7 0.0 0.058 13.4 0.0 1.9 2 0 0 2 2 2 0 EF-hand S10_plectin PF03501.10 EMC77778.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 EMC77778.1 - 0.05 13.6 0.1 1.9 8.5 0.0 2.4 2 1 0 2 2 2 0 EF hand I-set PF07679.11 EMC77779.1 - 4.4e-41 138.6 0.0 2.1e-12 46.6 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC77779.1 - 1.5e-36 124.3 0.0 2.6e-09 37.0 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.20 EMC77779.1 - 1.2e-27 95.7 0.0 2.3e-07 30.8 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 EMC77779.1 - 6.4e-19 68.2 0.0 6.3e-07 29.8 0.0 5.7 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 EMC77779.1 - 1.7e-18 66.6 0.0 0.00067 19.5 0.0 6.5 2 2 2 4 4 4 4 Immunoglobulin V-set domain VWA_2 PF13519.1 EMC77779.1 - 2.2e-07 31.1 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain C2-set_2 PF08205.7 EMC77779.1 - 0.013 15.3 0.1 2.9 7.8 0.0 3.4 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Arginosuc_synth PF00764.14 EMC77780.1 - 5.4e-138 460.2 0.0 6.1e-138 460.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EMC77780.1 - 9.5e-05 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EMC77780.1 - 0.00028 20.4 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EMC77780.1 - 0.0026 16.3 0.0 0.004 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Ish1 PF10281.4 EMC77780.1 - 0.087 12.9 0.0 0.73 9.9 0.0 2.4 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein KH_1 PF00013.24 EMC77781.1 - 7.2e-66 217.7 15.6 4.4e-18 64.6 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 EMC77781.1 - 7.6e-42 140.3 24.7 1.8e-11 43.4 0.5 4.8 5 0 0 5 5 5 4 KH domain KH_2 PF07650.12 EMC77781.1 - 3.6e-22 77.7 9.5 2.1e-05 24.0 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 EMC77781.1 - 4.7e-12 45.3 7.0 0.02 14.5 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 EMC77781.1 - 6.1e-05 22.7 6.4 4.2 7.2 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain DUF1897 PF09005.5 EMC77781.1 - 0.00039 19.8 11.6 0.00085 18.7 8.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) SET PF00856.23 EMC77782.1 - 0.017 15.4 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 SET domain Tissue_fac PF01108.12 EMC77782.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Tissue factor ECR1_N PF14382.1 EMC77783.1 - 2.9e-16 58.4 0.2 5.7e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ribosomal_L14 PF00238.14 EMC77783.1 - 0.019 14.7 0.0 4.1 7.1 0.0 2.6 3 0 0 3 3 3 0 Ribosomal protein L14p/L23e S1 PF00575.18 EMC77783.1 - 0.083 12.9 0.1 16 5.6 0.1 2.5 2 0 0 2 2 2 0 S1 RNA binding domain SH3_1 PF00018.23 EMC77784.1 - 4.2e-08 32.4 0.2 1.3e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC77784.1 - 8.4e-06 25.2 0.1 6e-05 22.5 0.2 2.2 2 1 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EMC77784.1 - 0.00082 19.5 0.2 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.12 EMC77784.1 - 0.0089 15.4 0.1 0.017 14.5 0.1 1.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.8 EMC77784.1 - 0.016 14.7 0.5 0.028 13.9 0.4 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_6 PF12913.2 EMC77784.1 - 0.017 14.3 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type CagE_TrbE_VirB PF03135.9 EMC77785.1 - 0.024 14.3 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system TraP PF07296.6 EMC77785.1 - 0.081 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 TraP protein Claudin_2 PF13903.1 EMC77786.1 - 9.6e-13 48.1 6.8 1.1e-12 47.9 4.7 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC77786.1 - 8.2e-05 22.3 5.0 0.00012 21.8 3.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Apq12 PF12716.2 EMC77786.1 - 0.11 12.2 1.1 0.25 11.0 0.8 1.6 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DAGK_cat PF00781.19 EMC77787.1 - 2.6e-21 75.4 0.1 4e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.3 EMC77787.1 - 0.00047 18.8 0.0 0.0014 17.3 0.0 1.6 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 NAD_kinase PF01513.16 EMC77787.1 - 0.00088 18.1 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase GATase PF00117.23 EMC77787.1 - 0.003 17.0 0.0 0.0064 15.9 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DUF2347 PF09804.4 EMC77788.1 - 1e-73 248.1 0.0 1.3e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EMC77788.1 - 9.8e-13 47.8 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EMC77788.1 - 4.5e-10 38.5 0.1 0.0022 16.5 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 Ph1570 PF09638.5 EMC77788.1 - 0.074 12.8 0.1 0.51 10.1 0.1 2.3 2 0 0 2 2 2 0 Ph1570 protein Pkinase PF00069.20 EMC77789.1 - 1e-47 162.4 0.0 1.4e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77789.1 - 3.2e-23 82.1 0.0 5.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SSB PF00436.20 EMC77790.1 - 2.3e-31 107.7 0.2 2.8e-31 107.4 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Ribosomal_L37 PF08561.5 EMC77791.1 - 8.7e-22 76.5 0.1 1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Peptidase_C14 PF00656.17 EMC77792.1 - 3.3e-19 69.5 0.0 9.9e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 Caspase domain Ig_2 PF13895.1 EMC77792.1 - 8.1e-16 57.9 1.2 1.1e-08 35.0 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC77792.1 - 1.8e-14 53.3 0.1 4.3e-08 32.8 0.0 3.2 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC77792.1 - 2.4e-13 50.3 5.4 2.9e-07 30.8 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 EMC77792.1 - 4.2e-08 33.1 0.7 0.00094 19.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC77792.1 - 6.2e-06 26.0 0.2 1.2 9.0 0.0 3.3 2 1 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC77792.1 - 0.028 14.3 1.6 0.16 11.8 0.1 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Pkinase_Tyr PF07714.12 EMC77793.1 - 1.5e-88 296.1 0.0 2e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77793.1 - 4.2e-46 157.2 0.0 7.1e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC77793.1 - 1.7e-20 72.5 0.0 3.6e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC77793.1 - 5.9e-10 38.3 0.0 1.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC77793.1 - 1.1e-07 31.3 0.0 3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC77793.1 - 0.00023 20.5 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 EMC77793.1 - 0.0015 18.3 0.0 0.006 16.3 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC77793.1 - 0.0049 15.8 0.0 0.011 14.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like SH3_3 PF08239.6 EMC77793.1 - 0.025 14.7 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RIO1 PF01163.17 EMC77793.1 - 0.027 13.8 0.1 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.17 EMC77794.1 - 4.2e-62 205.7 0.1 2.5e-19 68.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77794.1 - 5.9e-42 141.5 0.1 2.2e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC77794.1 - 1.5e-30 104.7 0.2 7.7e-11 41.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC77794.1 - 0.00095 18.9 0.0 0.1 12.4 0.0 2.5 1 1 1 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMC77794.1 - 0.0095 15.6 0.0 0.41 10.4 0.0 2.8 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif E2 PF08199.6 EMC77794.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage E2-like protein hSH3 PF14603.1 EMC77795.1 - 1.2e-15 57.3 0.0 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.12 EMC77795.1 - 0.00027 20.3 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC77795.1 - 0.0029 17.1 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC77795.1 - 0.062 12.6 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 SH3 domain CBFD_NFYB_HMF PF00808.18 EMC77797.1 - 8.2e-07 29.0 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC77797.1 - 2.7e-06 27.4 0.0 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EMC77797.1 - 0.0064 16.4 0.0 0.0076 16.1 0.0 1.1 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.10 EMC77797.1 - 0.07 12.9 0.1 0.078 12.7 0.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EMC77797.1 - 0.092 12.9 0.0 0.12 12.5 0.0 1.2 1 1 0 1 1 1 0 Kinetochore component CENP-S Glyco_hydro_56 PF01630.13 EMC77798.1 - 3.1e-140 466.6 0.3 3.9e-140 466.2 0.2 1.1 1 0 0 1 1 1 1 Hyaluronidase Arf PF00025.16 EMC77799.1 - 1.8e-38 131.5 0.0 2.1e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC77799.1 - 5.8e-13 48.5 0.0 6.4e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMC77799.1 - 7.8e-06 24.8 0.0 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 EMC77799.1 - 4.1e-05 24.0 0.0 7.5e-05 23.2 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EMC77799.1 - 6.7e-05 22.1 0.0 7.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC77799.1 - 0.00054 19.4 0.0 0.00063 19.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain 7tm_4 PF13853.1 EMC77800.1 - 6.1e-62 207.6 9.8 6.1e-62 207.6 6.8 2.0 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC77800.1 - 6.9e-34 117.1 16.5 1.1e-33 116.4 11.4 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77800.1 - 9.1e-05 21.7 11.3 0.00015 21.0 7.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Se-cys_synth_N PF12390.3 EMC77801.1 - 0.48 10.5 24.5 2.9 8.0 0.3 6.8 7 1 0 7 7 7 0 Selenocysteine synthase N terminal MOZART1 PF12554.3 EMC77801.1 - 1.6 8.2 4.5 27 4.3 0.0 3.4 4 0 0 4 4 4 0 Mitotic-spindle organizing gamma-tubulin ring associated OLF PF02191.11 EMC77802.1 - 3e-75 252.7 0.0 3.9e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Gal_Lectin PF02140.13 EMC77802.1 - 1.9e-23 82.5 1.0 3e-23 81.9 0.7 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain Lectin_C PF00059.16 EMC77805.1 - 6.9e-09 36.2 0.6 6.9e-09 36.2 0.4 1.6 1 1 1 2 2 2 1 Lectin C-type domain Herpes_UL45 PF05473.7 EMC77805.1 - 0.00011 21.6 0.2 0.00011 21.6 0.1 1.6 2 0 0 2 2 2 1 UL45 protein Choline_transpo PF04515.7 EMC77805.1 - 0.023 13.4 0.2 0.029 13.0 0.1 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Chordopox_A33R PF05966.7 EMC77805.1 - 0.086 11.6 0.3 0.11 11.2 0.2 1.4 1 1 0 1 1 1 0 Chordopoxvirus A33R protein Ly49 PF08391.5 EMC77805.1 - 0.11 12.5 0.4 0.11 12.5 0.3 2.4 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region TMEM52 PF14979.1 EMC77806.1 - 3.6e-57 192.5 0.5 4.2e-57 192.3 0.3 1.0 1 0 0 1 1 1 1 Transmembrane 52 Mucin PF01456.12 EMC77806.1 - 0.035 13.8 0.7 0.047 13.4 0.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Corona_S2 PF01601.11 EMC77806.1 - 0.23 9.4 2.2 0.3 9.1 1.5 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF3481 PF11980.3 EMC77806.1 - 0.3 10.9 4.6 0.42 10.4 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) WBP-1 PF11669.3 EMC77806.1 - 5.6 7.1 6.5 7.6 6.6 4.0 1.6 1 1 1 2 2 2 0 WW domain-binding protein 1 Atg8 PF02991.11 EMC77807.1 - 2.2e-49 165.7 0.2 2.5e-49 165.5 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMC77807.1 - 3.1e-08 33.6 0.0 3.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 VitD-bind_III PF09164.5 EMC77807.1 - 0.1 12.2 0.2 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Pkinase_Tyr PF07714.12 EMC77808.1 - 5e-65 219.1 0.0 6.8e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77808.1 - 1.3e-32 113.0 0.0 1.9e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EMC77808.1 - 6.9e-05 21.9 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TMEM154 PF15102.1 EMC77808.1 - 0.00052 19.7 0.1 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family 7tm_1 PF00001.16 EMC77808.1 - 0.013 14.6 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.1 EMC77808.1 - 0.046 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TLV_coat PF00429.14 EMC77809.1 - 1.1e-46 159.5 0.7 1.2e-46 159.3 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC77809.1 - 0.0088 15.6 0.2 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Retroviral envelope protein Synaptonemal_3 PF15191.1 EMC77810.1 - 1.4e-31 108.1 4.7 1.6e-31 107.9 3.3 1.0 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 Med9 PF07544.8 EMC77810.1 - 0.0086 15.7 1.8 1.2 8.9 0.1 2.1 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Borrelia_lipo_1 PF05714.6 EMC77810.1 - 0.036 13.1 0.5 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF4456 PF14644.1 EMC77810.1 - 0.05 12.8 0.6 0.057 12.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) BLOC1_2 PF10046.4 EMC77810.1 - 0.065 13.3 0.6 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rootletin PF15035.1 EMC77810.1 - 0.11 12.4 2.5 1.3 8.9 0.1 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 EMC77810.1 - 0.17 11.7 4.7 0.32 10.8 3.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 EMC77810.1 - 0.24 11.3 1.9 0.36 10.7 0.5 1.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CSD PF00313.17 EMC77811.1 - 5.3e-28 96.5 0.6 8.1e-28 96.0 0.4 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EMC77811.1 - 0.0036 16.7 0.0 0.0091 15.4 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease B OB domain DPPIV_N PF00930.16 EMC77812.1 - 9.5e-113 376.3 0.1 1.3e-112 375.8 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMC77812.1 - 3.1e-35 121.3 0.1 5.4e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.7 EMC77812.1 - 3.2e-06 26.6 0.3 0.016 14.8 0.0 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.13 EMC77812.1 - 6.5e-05 22.3 0.8 0.00021 20.6 0.6 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC77812.1 - 0.00073 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PTCB-BRCT PF12738.2 EMC77813.1 - 3.3e-56 187.0 2.1 6.8e-21 73.8 0.0 4.9 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.21 EMC77813.1 - 4.5e-54 180.5 1.3 3e-12 46.5 0.1 6.2 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain 7tm_1 PF00001.16 EMC77814.1 - 1.9e-76 256.5 9.3 1.9e-76 256.5 6.5 1.6 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC77814.1 - 0.1 11.6 7.5 0.031 13.4 2.9 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF3278 PF11683.3 EMC77814.1 - 1.2 9.1 4.8 6.3 6.8 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3278) INSIG PF07281.7 EMC77815.1 - 2.7e-49 167.1 6.2 1.6e-34 118.9 1.0 2.1 2 0 0 2 2 2 2 Insulin-induced protein (INSIG) RRM_6 PF14259.1 EMC77817.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC77817.1 - 0.0023 17.5 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EMC77818.1 - 3.2e-16 58.8 29.1 8.5e-09 35.1 8.4 3.0 2 1 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EMC77818.1 - 2.3e-11 43.6 20.1 2.4e-05 24.3 6.4 2.8 2 1 0 2 2 2 2 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC77818.1 - 4e-10 39.2 31.6 2.6e-05 23.8 9.0 3.2 2 1 1 3 3 3 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC77818.1 - 3.6e-08 32.9 26.6 0.00014 21.4 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC77818.1 - 4.7e-08 32.7 16.8 0.001 18.8 1.4 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMC77818.1 - 4.8e-07 29.7 30.2 0.00062 19.7 9.0 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC77818.1 - 2.1e-06 27.2 31.1 0.00035 20.1 9.1 3.3 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.22 EMC77818.1 - 1.1e-05 24.6 3.1 1.1e-05 24.6 2.2 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif Rtf2 PF04641.7 EMC77818.1 - 0.13 11.4 10.1 0.29 10.2 2.4 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger zf-UDP PF14569.1 EMC77818.1 - 0.52 10.0 9.0 2.9 7.6 3.0 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.1 EMC77818.1 - 3.2 7.5 30.0 0.046 13.4 5.9 4.1 3 2 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 EMC77818.1 - 3.4 7.3 23.3 0.58 9.7 0.3 3.3 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EMC77818.1 - 5.1 6.8 22.1 2.4 7.9 2.1 2.7 2 0 0 2 2 2 0 PHD-finger LMBR1 PF04791.11 EMC77819.1 - 1.1e-145 485.9 23.0 3e-145 484.4 15.9 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein 60KD_IMP PF02096.15 EMC77819.1 - 0.007 16.0 5.8 0.78 9.3 0.2 3.0 2 1 1 3 3 3 2 60Kd inner membrane protein DUF912 PF06024.7 EMC77819.1 - 0.018 15.0 0.3 0.018 15.0 0.2 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0233 PF06781.7 EMC77819.1 - 0.056 13.0 1.5 1.4 8.5 0.4 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) SH PF01445.12 EMC77819.1 - 0.21 11.2 0.1 0.21 11.2 0.1 3.0 3 0 0 3 3 3 0 Viral small hydrophobic protein Sigma_reg_N PF13800.1 EMC77819.1 - 1.7 8.7 0.0 1.7 8.7 0.0 4.3 4 1 1 5 5 5 0 Sigma factor regulator N-terminal S1FA PF04689.8 EMC77819.1 - 3.5 7.5 5.8 0.6 10.0 0.1 2.7 3 0 0 3 3 3 0 DNA binding protein S1FA Homeobox PF00046.24 EMC77820.1 - 1.7e-22 78.7 6.7 2.6e-22 78.1 4.7 1.3 1 0 0 1 1 1 1 Homeobox domain QLQ PF08880.6 EMC77820.1 - 0.0026 17.1 0.2 0.0026 17.1 0.2 1.7 2 0 0 2 2 2 1 QLQ LIN37 PF15306.1 EMC77820.1 - 0.027 14.4 3.1 0.043 13.7 2.2 1.3 1 0 0 1 1 1 0 LIN37 VID27 PF08553.5 EMC77820.1 - 0.055 11.6 3.7 0.061 11.5 2.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 EMC77820.1 - 0.32 8.9 2.7 0.35 8.8 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EMC77820.1 - 1.4 8.9 8.8 1.9 8.4 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HECT PF00632.20 EMC77821.1 - 1.3e-93 313.5 0.0 2.4e-93 312.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EMC77821.1 - 0.00037 19.8 0.1 0.001 18.5 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Lon_C PF05362.8 EMC77822.1 - 4.7e-25 88.1 0.0 1.7e-24 86.2 0.0 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EMC77822.1 - 1.1e-24 87.1 0.0 3.2e-24 85.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EMC77822.1 - 3.8e-24 85.4 8.1 3.8e-24 85.4 5.6 2.4 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 EMC77822.1 - 4.9e-09 36.0 0.0 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMC77822.1 - 2.2e-08 34.2 0.0 9.3e-08 32.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMC77822.1 - 1.6e-07 30.6 0.0 8.2e-06 25.0 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 EMC77822.1 - 2.6e-06 26.3 0.0 5.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 EMC77822.1 - 5.4e-06 26.5 3.8 2.4e-05 24.3 0.0 3.4 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EMC77822.1 - 7.2e-06 26.1 5.3 0.0001 22.4 0.0 4.2 4 2 0 4 4 4 1 AAA domain AAA_17 PF13207.1 EMC77822.1 - 1.3e-05 25.9 2.4 5.3e-05 24.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EMC77822.1 - 2.1e-05 24.3 0.5 8.5e-05 22.4 0.0 2.3 3 0 0 3 3 1 1 AAA domain RNA_helicase PF00910.17 EMC77822.1 - 0.0013 18.9 0.0 0.0032 17.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 EMC77822.1 - 0.0031 16.9 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Acetate_kinase PF00871.12 EMC77822.1 - 0.0033 16.0 1.0 0.0052 15.3 0.7 1.3 1 0 0 1 1 1 1 Acetokinase family AAA_24 PF13479.1 EMC77822.1 - 0.0044 16.6 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC77822.1 - 0.0059 16.0 0.0 0.033 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EMC77822.1 - 0.011 15.4 0.4 0.24 11.0 0.0 2.8 2 1 1 3 3 2 0 NTPase AAA_3 PF07726.6 EMC77822.1 - 0.015 14.9 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMC77822.1 - 0.016 15.5 0.0 0.016 15.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EMC77822.1 - 0.025 14.2 0.0 0.12 11.9 0.0 2.3 1 1 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 EMC77822.1 - 0.042 13.7 0.2 1.1 9.2 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EMC77822.1 - 0.049 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Parvo_NS1 PF01057.12 EMC77822.1 - 0.049 12.4 0.0 0.13 11.0 0.0 1.7 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_21 PF13304.1 EMC77822.1 - 0.058 13.3 1.1 1.8 8.4 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 EMC77822.1 - 0.059 13.2 0.0 0.22 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMC77822.1 - 0.061 12.8 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 EMC77822.1 - 0.063 13.5 1.0 0.47 10.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 EMC77822.1 - 0.064 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EMC77822.1 - 0.1 12.0 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EMC77822.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EMC77822.1 - 0.18 12.0 0.0 0.18 12.0 0.0 3.3 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EMC77822.1 - 1.6 8.2 0.0 1.6 8.2 0.0 3.3 2 2 0 2 2 1 0 AAA domain AbiH PF14253.1 EMC77822.1 - 2.9 7.4 8.0 2.9 7.4 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Ribosomal_L36e PF01158.13 EMC77823.1 - 6.3e-47 157.5 6.2 7.1e-47 157.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Filament PF00038.16 EMC77824.1 - 1.9e-80 270.6 47.4 2.6e-80 270.2 32.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.14 EMC77824.1 - 2.6e-20 72.6 0.5 4.8e-20 71.7 0.4 1.3 1 0 0 1 1 1 1 Lamin Tail Domain Myosin_tail_1 PF01576.14 EMC77824.1 - 0.00033 18.5 60.9 0.0041 14.9 1.1 3.3 1 1 1 3 3 3 3 Myosin tail BRE1 PF08647.6 EMC77824.1 - 0.0012 18.7 8.8 0.0012 18.7 6.1 3.8 2 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase IncA PF04156.9 EMC77824.1 - 0.0022 17.5 11.0 0.0022 17.5 7.6 3.3 1 1 2 3 3 3 2 IncA protein CagE_TrbE_VirB PF03135.9 EMC77824.1 - 0.022 14.5 0.6 0.022 14.5 0.4 1.8 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system DUF972 PF06156.8 EMC77824.1 - 0.089 13.1 0.5 0.089 13.1 0.3 5.2 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EMC77824.1 - 0.22 10.6 6.1 0.55 9.3 0.3 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PspB PF06667.7 EMC77824.1 - 0.92 9.4 5.4 0.25 11.2 0.4 2.7 2 0 0 2 2 2 0 Phage shock protein B zf-Tim10_DDP PF02953.10 EMC77825.1 - 1.2e-19 69.3 0.3 1.4e-19 69.0 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TIL PF01826.12 EMC77825.1 - 0.13 12.4 1.6 0.18 11.9 1.1 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Trypsin PF00089.21 EMC77826.1 - 5.6e-196 647.3 0.0 1.2e-69 234.2 0.0 3.3 3 0 0 3 3 3 3 Trypsin DUF1986 PF09342.6 EMC77826.1 - 2.3e-21 76.2 0.0 2.4e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF1986) Mucin PF01456.12 EMC77826.1 - 5.7 6.7 26.8 0.13 12.0 10.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Peptidase_A22B PF04258.8 EMC77827.1 - 1.7e-89 300.2 15.6 2.5e-89 299.6 10.8 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 EMC77827.1 - 3.7e-13 49.0 0.0 8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 PA domain Presenilin PF01080.12 EMC77827.1 - 0.085 11.6 17.1 0.039 12.7 2.6 2.6 2 1 0 2 2 2 0 Presenilin DUF4064 PF13273.1 EMC77827.1 - 0.097 12.7 2.5 0.47 10.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4191 PF13829.1 EMC77827.1 - 10 5.1 9.0 0.62 9.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) LSM PF01423.17 EMC77828.1 - 3.6e-05 23.2 0.0 0.067 12.7 0.0 2.1 2 0 0 2 2 2 2 LSM domain Kelch_6 PF13964.1 EMC77829.1 - 4.5e-23 80.4 7.0 0.00014 21.8 0.1 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EMC77829.1 - 2.2e-22 78.3 13.8 4.3e-05 22.9 0.2 6.8 6 1 0 6 6 6 4 Kelch motif BACK PF07707.10 EMC77829.1 - 2.8e-21 75.2 0.1 2.4e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 EMC77829.1 - 1.8e-07 30.9 7.3 0.087 12.8 0.1 5.6 6 0 0 6 6 6 3 Kelch motif BTB PF00651.26 EMC77829.1 - 1.8e-07 31.1 0.0 2.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 EMC77829.1 - 2.5e-07 30.6 4.4 0.0041 17.2 0.0 5.6 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC77829.1 - 5.2e-07 29.1 8.7 0.26 11.1 0.0 5.7 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EMC77829.1 - 1.1e-06 28.2 14.5 0.078 12.7 0.0 6.7 6 1 1 7 7 7 3 Galactose oxidase, central domain TRAM_LAG1_CLN8 PF03798.11 EMC77830.1 - 1.9e-38 132.0 25.7 2.5e-38 131.6 17.8 1.2 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 EMC77830.1 - 2.5e-05 23.8 0.1 6e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain Ctr PF04145.10 EMC77830.1 - 0.031 14.3 2.0 0.064 13.3 0.0 2.4 2 1 1 3 3 3 0 Ctr copper transporter family Homez PF11569.3 EMC77830.1 - 0.05 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Lectin_C PF00059.16 EMC77831.1 - 2e-17 63.7 2.0 2.5e-17 63.4 1.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain STOP PF05217.7 EMC77833.1 - 1e-36 126.6 22.8 5.8e-26 91.5 5.7 2.6 1 1 1 2 2 2 2 STOP protein TSP_1 PF00090.14 EMC77834.1 - 1e-54 182.4 166.9 1.5e-06 28.1 2.8 15.5 14 1 0 14 14 14 12 Thrombospondin type 1 domain I-set PF07679.11 EMC77834.1 - 5.5e-31 106.2 0.0 1.2e-13 50.6 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC77834.1 - 1.1e-26 92.7 0.1 5e-11 42.5 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 EMC77834.1 - 1e-17 64.3 3.0 6.2e-06 26.6 0.1 4.8 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 EMC77834.1 - 6.1e-16 58.3 0.1 1.4e-08 34.7 0.0 3.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 EMC77834.1 - 6e-11 42.2 0.8 0.0016 18.3 0.0 4.7 4 2 0 4 4 4 2 Immunoglobulin V-set domain PLAC PF08686.6 EMC77834.1 - 1e-09 38.5 14.0 3e-09 36.9 8.3 3.2 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain ADAM_spacer1 PF05986.9 EMC77834.1 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Filament PF00038.16 EMC77835.1 - 4.6e-51 174.1 38.2 4.6e-51 174.1 26.4 1.3 2 0 0 2 2 2 1 Intermediate filament protein LTD PF00932.14 EMC77835.1 - 2.8e-17 62.8 0.2 4.6e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 Lamin Tail Domain DUF1697 PF08002.6 EMC77835.1 - 0.14 12.2 2.5 0.23 11.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1697) Activator-TraM PF11657.3 EMC77835.1 - 3.5 7.0 11.7 0.35 10.3 4.6 2.0 2 1 0 2 2 2 0 Transcriptional activator TraM BAR PF03114.13 EMC77836.1 - 6.4e-75 251.5 8.1 7.7e-75 251.3 5.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EMC77836.1 - 8.7e-15 53.8 0.1 2.5e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC77836.1 - 1.4e-14 53.4 0.1 2.3e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC77836.1 - 8.6e-14 50.7 0.0 2.8e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.4 EMC77836.1 - 8.5e-08 31.4 4.8 4e-06 25.9 1.1 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-C2H2_4 PF13894.1 EMC77837.1 - 1.4e-10 40.7 33.5 0.0086 16.3 1.0 7.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.2 EMC77837.1 - 4.9e-09 36.0 20.8 0.0023 18.0 0.1 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC77837.1 - 0.00013 22.0 19.1 0.062 13.4 1.0 4.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMC77837.1 - 0.00022 21.3 42.3 0.004 17.4 1.3 7.3 6 1 0 6 6 6 4 Zinc finger, C2H2 type PWWP PF00855.12 EMC77838.1 - 8.2e-08 32.3 0.0 8.2e-08 32.3 0.0 2.1 2 1 0 2 2 2 1 PWWP domain Pox_Ag35 PF03286.9 EMC77838.1 - 0.61 9.5 12.6 0.93 8.9 8.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 EMC77838.1 - 1.8 7.3 12.8 2.2 7.0 8.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 EMC77838.1 - 5.2 5.4 9.2 6.6 5.1 6.4 1.1 1 0 0 1 1 1 0 Raftlin Pkinase PF00069.20 EMC77839.1 - 6.4e-59 199.2 0.0 4.2e-38 131.0 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77839.1 - 9.5e-31 106.7 0.0 8.3e-24 84.0 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMC77839.1 - 0.00028 20.6 0.1 0.0052 16.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC77839.1 - 0.0011 18.0 0.0 0.0083 15.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC77839.1 - 0.024 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ACBP PF00887.14 EMC77840.1 - 2.5e-27 94.3 0.0 5.3e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DELLA PF12041.3 EMC77840.1 - 0.065 12.9 1.3 9.6 5.9 0.2 2.9 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal DALR_1 PF05746.10 EMC77840.1 - 0.086 12.7 0.4 0.6 10.0 0.0 2.4 1 1 1 2 2 2 0 DALR anticodon binding domain Podoplanin PF05808.6 EMC77840.1 - 0.12 11.9 0.3 0.25 10.8 0.2 1.5 1 0 0 1 1 1 0 Podoplanin Abi_HHR PF07815.9 EMC77841.1 - 3.4e-34 116.7 0.4 6.9e-34 115.8 0.3 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.23 EMC77841.1 - 8.2e-17 60.3 0.1 1.3e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC77841.1 - 3.1e-15 55.4 0.2 6.7e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC77841.1 - 1.4e-10 40.4 0.1 2.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain polyprenyl_synt PF00348.12 EMC77842.1 - 3.1e-54 183.5 0.1 3.9e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EMC77842.1 - 0.001 18.5 0.3 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 UPF0061 PF02696.9 EMC77843.1 - 1.4e-80 270.9 0.0 1.8e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family UPF0061 PF02696.9 EMC77844.1 - 0.00084 17.7 0.0 0.00096 17.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family RA PF00788.18 EMC77845.1 - 6.8e-13 48.9 1.0 4.5e-12 46.2 0.3 2.3 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 EMC77845.1 - 3.4e-12 46.4 0.2 1.2e-11 44.7 0.1 2.0 2 0 0 2 2 2 1 PH domain TNFR_c6 PF00020.13 EMC77846.1 - 3.9e-06 26.8 9.9 8.8e-06 25.6 6.9 1.6 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region EGF_CA PF07645.10 EMC77846.1 - 0.007 16.3 0.2 0.007 16.3 0.1 2.7 2 1 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 EMC77846.1 - 0.067 12.8 3.1 0.15 11.7 2.1 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like Pyridoxal_deC PF00282.14 EMC77847.1 - 1.7e-131 438.1 0.0 2e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMC77847.1 - 0.00012 20.9 0.0 0.0023 16.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC77847.1 - 0.00028 20.1 0.0 0.00041 19.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase 7tm_3 PF00003.17 EMC77848.1 - 3.4e-07 29.8 7.5 4.9e-07 29.3 5.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PRA1 PF03208.14 EMC77848.1 - 0.3 10.4 5.5 0.1 11.9 0.7 2.1 1 1 0 2 2 2 0 PRA1 family protein A2M_comp PF07678.9 EMC77851.1 - 6.6e-64 215.4 1.1 1.5e-63 214.3 0.8 1.6 1 1 0 1 1 1 1 A-macroglobulin complement component A2M_recep PF07677.9 EMC77851.1 - 1.2e-32 111.9 0.1 1.9e-31 108.0 0.0 2.7 2 0 0 2 2 2 1 A-macroglobulin receptor A2M PF00207.17 EMC77851.1 - 4e-32 109.6 0.1 1.7e-31 107.6 0.1 2.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 EMC77851.1 - 4.2e-27 94.6 3.9 2.7e-26 91.9 0.1 3.8 4 0 0 4 4 4 1 Alpha-2-macroglobulin family N-terminal region NTR PF01759.16 EMC77851.1 - 6.8e-24 83.5 0.1 3.6e-23 81.2 0.0 2.3 2 0 0 2 2 2 1 UNC-6/NTR/C345C module A2M_N PF01835.14 EMC77851.1 - 7.6e-18 64.5 0.0 1.6e-16 60.3 0.0 3.1 3 0 0 3 3 3 1 MG2 domain ANATO PF01821.13 EMC77851.1 - 1.4e-15 57.0 8.0 3.5e-15 55.8 5.5 1.7 1 0 0 1 1 1 1 Anaphylotoxin-like domain Thiol-ester_cl PF10569.4 EMC77851.1 - 1.7e-14 52.7 0.0 3.9e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 EMC77851.1 - 4.8e-05 23.7 0.1 0.043 14.2 0.0 3.0 1 1 2 3 3 3 3 Prenyltransferase-like FAD_binding_9 PF08021.6 EMC77851.1 - 0.029 14.3 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF2547 PF10818.3 EMC77852.1 - 0.053 14.1 2.2 29 5.3 0.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF2547) Metal_resist PF13801.1 EMC77853.1 - 0.0053 16.7 0.7 0.0085 16.0 0.5 1.3 1 0 0 1 1 1 1 Heavy-metal resistance Lectin_C PF00059.16 EMC77853.1 - 0.051 14.2 0.0 0.094 13.3 0.0 1.4 1 0 0 1 1 1 0 Lectin C-type domain Herpes_UL45 PF05473.7 EMC77853.1 - 0.27 10.6 1.0 0.45 9.8 0.1 1.7 1 1 2 3 3 3 0 UL45 protein Gar1 PF04410.9 EMC77854.1 - 1.8e-40 137.9 0.1 2.4e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PAT1 PF09770.4 EMC77854.1 - 1.2 7.3 15.9 1.4 7.0 11.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 7tm_1 PF00001.16 EMC77855.1 - 6.9e-42 143.3 13.3 8.9e-42 142.9 9.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC77855.1 - 1.8e-07 30.5 22.4 3e-05 23.3 9.7 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx K1 PF02960.9 EMC77855.1 - 0.016 15.2 0.3 0.083 12.9 0.0 2.3 2 0 0 2 2 2 0 K1 glycoprotein DUF2962 PF11176.3 EMC77856.1 - 1.4e-43 148.1 8.3 1.4e-43 148.1 5.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2962) RINGv PF12906.2 EMC77857.1 - 6.8e-16 58.0 16.0 1.9e-15 56.6 11.1 1.8 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.7 EMC77857.1 - 0.035 13.8 0.3 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component 7tm_7 PF08395.7 EMC77857.1 - 0.43 9.5 3.3 0.39 9.6 1.5 1.4 1 1 1 2 2 2 0 7tm Chemosensory receptor FANCL_C PF11793.3 EMC77857.1 - 4.7 7.2 12.2 2.8 7.9 6.2 2.4 3 0 0 3 3 3 0 FANCL C-terminal domain ING PF12998.2 EMC77858.1 - 1.1e-15 57.7 3.6 1.1e-15 57.7 2.5 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Myosin_tail_1 PF01576.14 EMC77858.1 - 0.011 13.5 3.7 0.013 13.2 2.5 1.1 1 0 0 1 1 1 0 Myosin tail Med11 PF10280.4 EMC77858.1 - 0.41 10.6 3.9 0.14 12.1 0.3 2.0 2 1 0 2 2 2 0 Mediator complex protein Tetraspannin PF00335.15 EMC77859.1 - 5e-33 114.2 8.8 6.4e-33 113.8 6.1 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3399 PF11879.3 EMC77860.1 - 4.6e-12 46.0 2.4 4.6e-12 46.0 1.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ank PF00023.25 EMC77861.1 - 6.6e-35 117.1 4.3 1.6e-07 30.7 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMC77861.1 - 5.9e-31 106.6 4.2 5.8e-15 55.3 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC77861.1 - 1.7e-28 97.9 8.2 3.1e-09 36.7 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC77861.1 - 4.9e-24 84.2 1.5 5e-08 33.2 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77861.1 - 2.4e-20 70.5 3.1 2.7e-05 23.9 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Mic1 PF07035.7 EMC77861.1 - 0.012 14.9 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 Colon cancer-associated protein Mic1-like ABC_membrane PF00664.18 EMC77862.1 - 2.1e-98 329.1 39.6 9.9e-50 169.4 11.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region CFTR_R PF14396.1 EMC77862.1 - 8.2e-93 309.6 1.6 8.2e-93 309.6 1.1 1.8 2 0 0 2 2 2 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_tran PF00005.22 EMC77862.1 - 2e-55 186.8 0.0 1.7e-30 106.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC77862.1 - 1.3e-06 27.8 0.0 0.02 14.1 0.0 3.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMC77862.1 - 1.5e-06 27.6 0.8 0.0015 17.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EMC77862.1 - 3.5e-06 26.1 0.1 0.025 13.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.1 EMC77862.1 - 3.7e-06 27.1 4.8 0.014 15.4 0.0 4.3 4 1 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EMC77862.1 - 9.3e-06 25.7 0.2 0.019 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EMC77862.1 - 3.3e-05 23.1 0.5 0.028 13.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EMC77862.1 - 0.00025 21.4 0.1 0.99 9.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 EMC77862.1 - 0.00039 20.3 1.1 0.24 11.1 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_15 PF13175.1 EMC77862.1 - 0.00048 19.2 3.3 0.00067 18.8 0.0 2.9 5 0 0 5 5 5 1 AAA ATPase domain AAA_23 PF13476.1 EMC77862.1 - 0.0018 18.6 10.1 0.075 13.3 0.0 4.1 5 0 0 5 5 3 1 AAA domain NACHT PF05729.7 EMC77862.1 - 0.0022 17.6 0.5 1.8 8.1 0.0 2.8 2 0 0 2 2 2 2 NACHT domain NTPase_1 PF03266.10 EMC77862.1 - 0.0025 17.5 0.5 0.12 12.0 0.0 2.7 3 0 0 3 3 2 1 NTPase AAA_17 PF13207.1 EMC77862.1 - 0.0032 18.2 0.0 1.4 9.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EMC77862.1 - 0.0035 16.1 0.2 0.079 11.7 0.0 2.4 3 0 0 3 3 3 1 ArgK protein AAA_25 PF13481.1 EMC77862.1 - 0.0053 16.1 0.1 3 7.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC77862.1 - 0.0054 16.8 0.3 3.7 7.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EMC77862.1 - 0.0073 15.9 0.0 0.93 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC77862.1 - 0.0099 14.9 0.3 0.43 9.6 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin UPF0079 PF02367.12 EMC77862.1 - 0.017 14.7 0.4 0.81 9.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EMC77862.1 - 0.018 15.0 0.4 0.71 9.8 0.2 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 EMC77862.1 - 0.047 13.1 2.0 5.2 6.4 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EMC77862.1 - 0.059 12.7 0.2 13 5.1 0.2 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EMC77862.1 - 0.061 13.6 0.0 5.3 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EMC77862.1 - 0.091 12.2 0.2 10 5.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EMC77862.1 - 0.1 12.0 0.5 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EMC77862.1 - 0.11 12.7 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EMC77862.1 - 0.17 11.6 0.1 13 5.5 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Ank_2 PF12796.2 EMC77863.1 - 9.5e-46 154.0 2.3 8.8e-19 67.6 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC77863.1 - 8.3e-32 107.4 3.4 7.6e-09 34.9 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EMC77863.1 - 1.9e-24 85.5 0.2 1.4e-11 44.5 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC77863.1 - 5.6e-24 83.6 0.8 2.5e-09 37.0 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77863.1 - 8.2e-21 72.0 1.4 0.00041 20.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat SAM_2 PF07647.12 EMC77863.1 - 5.5e-09 35.7 0.2 1.3e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC77863.1 - 2.7e-08 33.8 0.3 5.8e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF643 PF04867.7 EMC77863.1 - 0.032 14.6 0.1 0.08 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF643) Collagen PF01391.13 EMC77864.1 - 1.7e-26 91.4 93.5 6.3e-10 38.4 22.6 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Troponin-I_N PF11636.3 EMC77865.1 - 0.92 9.2 4.6 26 4.6 0.0 2.5 2 0 0 2 2 2 0 Troponin I residues 1-32 UQ_con PF00179.21 EMC77866.1 - 2.5e-10 39.9 0.0 8.4e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC77866.1 - 0.00041 20.1 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B CDC45 PF02724.9 EMC77866.1 - 0.093 10.7 2.2 0.19 9.7 1.5 1.5 2 0 0 2 2 2 0 CDC45-like protein Neur_chan_LBD PF02931.18 EMC77867.1 - 2e-32 112.1 0.0 2.3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC77867.1 - 6.8e-25 88.3 11.3 9.6e-25 87.8 7.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.4 EMC77867.1 - 0.024 14.0 3.2 0.031 13.6 2.2 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) GDA1_CD39 PF01150.12 EMC77869.1 - 2.4e-91 306.4 0.0 2.9e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TMEM141 PF15110.1 EMC77870.1 - 1.8e-14 53.8 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 TMEM141 protein family DUF4610 PF15384.1 EMC77871.1 - 4.4e-22 78.5 0.4 4.9e-22 78.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4610) GST_C_2 PF13410.1 EMC77872.1 - 6.9e-07 29.0 0.1 9.1e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC77872.1 - 0.0015 18.9 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC77872.1 - 0.0038 17.1 0.0 0.011 15.7 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.22 EMC77873.1 - 6.5e-58 194.8 0.0 1e-29 103.5 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 EMC77873.1 - 1e-57 195.7 42.0 1.6e-39 135.8 9.7 3.5 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EMC77873.1 - 1.6e-21 77.5 0.3 3.9e-08 33.6 0.1 4.4 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EMC77873.1 - 0.00071 19.9 1.2 0.22 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EMC77873.1 - 0.00078 18.5 0.0 2.2 7.2 0.0 3.2 4 0 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.1 EMC77873.1 - 0.0039 17.0 0.0 2.6 8.0 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EMC77873.1 - 0.03 13.7 3.3 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EMC77873.1 - 0.067 12.7 3.9 0.71 9.4 0.2 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EMC77873.1 - 0.12 11.4 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 EMC77873.1 - 0.15 11.2 0.7 1.2 8.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Glyco_transf_10 PF00852.14 EMC77874.1 - 1.2e-113 379.3 0.4 1.4e-113 379.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Pou PF00157.12 EMC77875.1 - 1.3e-33 114.4 0.1 2.9e-33 113.3 0.1 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 EMC77875.1 - 9.5e-19 66.7 0.3 1.8e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC77875.1 - 0.0037 16.9 0.1 0.0084 15.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_19 PF12844.2 EMC77875.1 - 0.011 15.7 0.0 2.4 8.2 0.0 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain NPDC1 PF06809.6 EMC77876.1 - 2.4e-59 200.8 0.4 2.6e-59 200.7 0.3 1.0 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) FAM163 PF15069.1 EMC77876.1 - 0.019 15.5 0.5 0.038 14.5 0.4 1.4 1 1 0 1 1 1 0 FAM163 family 7tm_4 PF13853.1 EMC77877.1 - 1.8e-38 131.5 8.2 1.8e-38 131.5 5.7 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC77877.1 - 8.1e-35 120.1 14.5 8.1e-35 120.1 10.0 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF1345 PF07077.6 EMC77877.1 - 0.083 12.4 0.3 0.083 12.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Lipocalin PF00061.18 EMC77878.1 - 0.00022 21.2 0.0 0.00024 21.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 EMC77880.1 - 1.7e-32 112.4 0.2 5.5e-17 62.1 0.1 2.0 2 0 0 2 2 2 2 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 EMC77880.1 - 0.0058 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Triabin Lipocalin_2 PF08212.7 EMC77880.1 - 0.01 15.6 0.2 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Lipocalin-like domain Lipocalin PF00061.18 EMC77881.1 - 1.5e-16 60.6 0.0 1.8e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family NDUFA12 PF05071.11 EMC77882.1 - 5.2e-30 104.0 3.7 6.8e-30 103.6 2.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hormone_recep PF00104.25 EMC77883.1 - 5.1e-33 113.9 0.6 9e-33 113.1 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC77883.1 - 1.7e-31 108.2 15.5 3.9e-31 107.0 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2318 PF10080.4 EMC77883.1 - 0.019 14.7 0.8 0.019 14.7 0.6 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) RhoGEF PF00621.15 EMC77884.1 - 9.7e-40 136.3 1.7 9.7e-40 136.3 1.2 2.3 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EMC77884.1 - 1.4e-20 72.9 10.2 3.2e-20 71.7 7.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EMC77884.1 - 3.7e-17 62.4 1.2 5.6e-09 36.1 0.0 3.0 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC77884.1 - 5.5e-07 29.8 0.6 0.052 13.8 0.0 3.1 2 0 0 2 2 2 2 Pleckstrin homology domain FYVE_2 PF02318.11 EMC77884.1 - 0.0038 17.1 10.5 0.0038 17.1 7.3 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger Vezatin PF12632.2 EMC77885.1 - 6.9e-59 198.9 2.0 1.5e-58 197.8 1.4 1.6 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes KRAB PF01352.22 EMC77886.1 - 7.4e-13 47.7 0.2 1.4e-12 46.8 0.1 1.4 1 1 0 1 1 1 1 KRAB box Recep_L_domain PF01030.19 EMC77887.1 - 2e-29 101.8 0.0 2.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Receptor L domain CDH PF02611.10 EMC77887.1 - 0.083 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Pkinase_Tyr PF07714.12 EMC77888.1 - 3.3e-24 85.3 0.0 7.5e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77888.1 - 2.1e-12 46.7 0.0 3.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GF_recep_IV PF14843.1 EMC77888.1 - 2e-11 43.6 4.6 2.9e-11 43.0 3.2 1.2 1 0 0 1 1 1 1 Growth factor receptor domain IV Protocadherin PF08374.6 EMC77888.1 - 5.7e-05 22.8 0.0 8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.1 EMC77888.1 - 0.00026 21.2 0.2 0.00065 20.0 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EMC77888.1 - 0.00081 18.8 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1191 PF06697.7 EMC77888.1 - 0.0021 16.9 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4381 PF14316.1 EMC77888.1 - 0.02 14.9 0.2 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Marek_A PF02124.10 EMC77888.1 - 0.03 13.8 0.6 0.05 13.0 0.4 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A Herpes_gE PF02480.11 EMC77888.1 - 0.07 11.3 0.1 0.1 10.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EMC77888.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family MFS_2 PF13347.1 EMC77888.1 - 0.083 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein TMEM154 PF15102.1 EMC77888.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.7 EMC77888.1 - 0.14 11.5 0.7 0.24 10.7 0.5 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor FAM176 PF14851.1 EMC77888.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Antistasin PF02822.9 EMC77888.1 - 7.3 7.0 10.9 4.2 7.7 0.0 3.1 2 1 1 3 3 3 0 Antistasin family Rdx PF10262.4 EMC77889.1 - 8.1e-18 64.2 0.0 9.4e-18 64.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family adh_short PF00106.20 EMC77890.1 - 7.1e-13 48.8 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC77890.1 - 0.0012 18.6 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC77890.1 - 0.086 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain zf-H2C2_2 PF13465.1 EMC77891.1 - 5e-25 86.5 31.8 1.8e-07 31.1 0.6 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC77891.1 - 4.6e-15 54.9 41.8 2.1e-05 24.5 0.3 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77891.1 - 5.7e-09 35.6 40.3 0.0005 20.2 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC77891.1 - 0.018 15.2 31.0 0.26 11.5 1.8 5.9 5 0 0 5 5 5 0 C2H2-type zinc-finger domain GAGA PF09237.6 EMC77891.1 - 0.055 13.0 2.2 0.11 12.0 0.1 2.6 1 1 0 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.3 EMC77891.1 - 0.24 11.5 26.3 0.36 11.0 0.2 6.0 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 EMC77891.1 - 0.38 10.5 23.2 0.61 9.8 1.2 3.9 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AKAP95 PF04988.7 EMC77891.1 - 0.94 9.2 8.8 0.62 9.8 0.1 2.9 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 EMC77891.1 - 2.6 8.0 38.6 1.2 9.1 1.0 6.8 6 2 0 6 6 6 0 C2H2-type zinc finger Sp38 PF07354.7 EMC77892.1 - 5.8e-122 405.5 8.4 6.8e-122 405.3 5.8 1.0 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) HORMA PF02301.13 EMC77892.1 - 0.042 13.3 0.2 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 HORMA domain LRR_8 PF13855.1 EMC77893.1 - 1e-16 60.3 2.1 4.9e-10 39.0 0.0 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EMC77893.1 - 2.9e-08 32.6 9.1 0.012 15.4 0.3 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 EMC77893.1 - 2e-06 27.2 5.1 0.0045 16.5 0.1 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF3700 PF12481.3 EMC77893.1 - 0.0001 21.6 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein LRR_7 PF13504.1 EMC77893.1 - 0.016 15.3 9.1 3.3 8.3 0.1 5.5 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EMC77893.1 - 0.035 14.1 4.0 6.5 7.1 0.2 3.8 2 1 1 3 3 3 0 Leucine Rich repeat LRRNT PF01462.13 EMC77893.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain ORMDL PF04061.9 EMC77894.1 - 9e-53 177.4 4.5 1e-52 177.2 3.1 1.0 1 0 0 1 1 1 1 ORMDL family 7tm_3 PF00003.17 EMC77894.1 - 0.022 14.0 0.2 0.022 14.0 0.2 1.8 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Gasdermin PF04598.7 EMC77895.1 - 9e-43 146.6 0.0 1e-42 146.5 0.0 1.0 1 0 0 1 1 1 1 Gasdermin family APG5 PF04106.7 EMC77895.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 Gasdermin PF04598.7 EMC77896.1 - 5.6e-08 31.9 0.5 6.8e-08 31.7 0.3 1.0 1 0 0 1 1 1 1 Gasdermin family Rpn3_C PF08375.6 EMC77897.1 - 6.9e-27 93.6 2.0 6.9e-27 93.6 1.4 2.3 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EMC77897.1 - 4e-24 84.9 0.6 9.7e-24 83.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EMC77897.1 - 0.00089 19.0 0.2 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EMC77897.1 - 0.0059 16.5 9.0 0.068 13.1 1.7 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC77897.1 - 0.037 13.9 0.5 3.1 7.7 0.0 3.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 EMC77897.1 - 0.072 13.0 1.6 0.42 10.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat IL6 PF00489.12 EMC77898.1 - 2.3e-24 85.7 0.0 2.5e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family zf-C4 PF00105.13 EMC77900.1 - 1.7e-32 111.4 14.3 1.9e-32 111.2 9.9 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PAN_3 PF08277.7 EMC77900.1 - 0.015 14.9 1.8 0.023 14.2 1.2 1.3 1 0 0 1 1 1 0 PAN-like domain ISAV_HA PF06215.6 EMC77900.1 - 0.017 13.4 1.5 0.019 13.2 1.1 1.0 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin DUF164 PF02591.10 EMC77900.1 - 0.045 13.5 2.3 0.045 13.5 1.6 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_6 PF12837.2 EMC77900.1 - 0.051 13.4 0.7 0.051 13.4 0.5 3.1 4 0 0 4 4 4 0 4Fe-4S binding domain Btz PF09405.5 EMC77902.1 - 1.2e-16 60.9 1.7 4.3e-16 59.1 1.2 2.1 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding PAX PF00292.13 EMC77903.1 - 3.7e-74 246.4 0.9 5.3e-74 245.8 0.6 1.2 1 0 0 1 1 1 1 'Paired box' domain Pax7 PF12360.3 EMC77903.1 - 1.1e-23 83.2 7.8 2.8e-23 81.9 5.4 1.7 1 0 0 1 1 1 1 Paired box protein 7 Homeobox PF00046.24 EMC77903.1 - 6e-23 80.2 6.7 1e-22 79.4 4.6 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EMC77903.1 - 7.4e-06 25.4 1.0 0.00052 19.5 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EMC77903.1 - 0.00015 22.4 2.3 0.18 12.6 0.0 2.8 2 0 0 2 2 2 2 Homeodomain-like domain Homeobox_KN PF05920.6 EMC77903.1 - 0.00029 20.4 0.4 0.0007 19.2 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ribosomal_S13_N PF08069.7 EMC77903.1 - 0.12 12.2 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain QLQ PF08880.6 EMC77903.1 - 0.2 11.1 0.7 4.3 6.8 0.1 2.9 3 0 0 3 3 3 0 QLQ Pkinase_Tyr PF07714.12 EMC77904.1 - 1.4e-94 315.9 0.0 2.1e-94 315.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC77904.1 - 2.5e-78 261.9 0.0 4.6e-78 261.0 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC77904.1 - 3.7e-46 157.3 0.0 5.8e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC77904.1 - 9.2e-34 115.4 2.5 6.3e-17 61.4 0.0 3.0 4 0 0 4 4 4 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC77904.1 - 9.5e-26 90.0 0.2 1.9e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_2 PF07647.12 EMC77904.1 - 7.3e-21 73.7 0.0 1.4e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC77904.1 - 1.1e-19 70.3 0.0 2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC77904.1 - 2.5e-06 26.9 5.1 2.5e-06 26.9 3.5 2.9 2 2 1 3 3 3 1 GCC2 and GCC3 SusE PF14292.1 EMC77904.1 - 0.0011 18.7 0.1 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 SusE outer membrane protein Interfer-bind PF09294.5 EMC77904.1 - 0.0019 18.2 0.3 0.76 9.8 0.0 3.7 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III CD34_antigen PF06365.7 EMC77904.1 - 0.028 14.0 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 CD34/Podocalyxin family Tissue_fac PF01108.12 EMC77904.1 - 0.082 12.6 0.1 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 Tissue factor TMEM154 PF15102.1 EMC77904.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family His_Phos_2 PF00328.17 EMC77905.1 - 2.5e-41 142.1 0.1 2.9e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) C1q PF00386.16 EMC77908.1 - 0.0027 17.7 0.1 0.0055 16.7 0.1 1.6 1 1 0 1 1 1 1 C1q domain PP2C PF00481.16 EMC77909.1 - 2.4e-63 213.8 0.2 3e-63 213.5 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMC77909.1 - 3.2e-06 26.6 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3536 PF12055.3 EMC77909.1 - 0.1 11.7 0.1 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3536) Mab-21 PF03281.9 EMC77910.1 - 1.2e-19 70.5 0.0 1.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein EGF PF00008.22 EMC77911.1 - 1.4e-76 251.8 214.9 4e-08 33.0 5.5 14.7 14 0 0 14 14 14 13 EGF-like domain fn3 PF00041.16 EMC77911.1 - 1.5e-35 121.1 6.8 7.2e-13 48.4 0.7 3.4 3 0 0 3 3 3 3 Fibronectin type III domain NIDO PF06119.9 EMC77911.1 - 1.9e-31 108.6 0.1 4.2e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.10 EMC77911.1 - 5.4e-21 74.3 202.6 1.2e-08 34.7 4.0 14.5 8 5 6 14 14 14 10 Calcium-binding EGF domain EGF_2 PF07974.8 EMC77911.1 - 6.9e-16 58.1 241.8 0.022 14.8 7.5 14.5 14 0 0 14 14 14 12 EGF-like domain hEGF PF12661.2 EMC77911.1 - 1.3e-10 40.6 142.2 0.0052 16.7 1.1 15.7 17 0 0 17 17 17 11 Human growth factor-like EGF cEGF PF12662.2 EMC77911.1 - 0.0022 17.6 1.3 0.0022 17.6 0.9 15.9 15 2 0 15 15 15 5 Complement Clr-like EGF-like EGF_3 PF12947.2 EMC77911.1 - 0.0032 17.3 3.5 0.0032 17.3 2.4 14.7 14 0 0 14 14 14 4 EGF domain Pkinase PF00069.20 EMC77913.1 - 6.3e-58 195.9 0.0 1.1e-57 195.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77913.1 - 4.5e-23 81.6 0.0 8.2e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.1 EMC77913.1 - 1.2e-15 57.7 0.0 1.3e-06 28.7 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS PF00989.19 EMC77913.1 - 3.3e-12 46.1 0.0 2.4e-06 27.3 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 EMC77913.1 - 0.00033 20.4 0.0 0.023 14.5 0.0 3.2 3 0 0 3 3 3 1 PAS domain Kinase-like PF14531.1 EMC77913.1 - 0.0034 16.3 0.0 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC77913.1 - 0.038 13.0 0.0 0.093 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 EMC77914.1 - 4.7e-41 137.7 51.3 3.2e-10 39.3 2.0 6.2 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EMC77914.1 - 2.4e-24 85.8 22.3 1.1e-08 34.9 3.3 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.1 EMC77914.1 - 2.9e-23 81.3 65.6 1.9e-08 33.8 5.6 4.9 2 1 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EMC77914.1 - 2.3e-13 48.1 35.4 0.096 12.7 0.2 10.7 10 1 1 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 EMC77914.1 - 5.1e-10 38.3 25.9 0.11 12.6 0.3 10.0 7 4 1 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 EMC77914.1 - 1.2e-08 33.7 21.3 0.69 10.3 0.1 9.8 8 3 3 11 11 11 3 Leucine rich repeat UB2H PF14814.1 EMC77914.1 - 0.59 9.8 9.2 32 4.3 0.1 5.3 2 2 5 7 7 7 0 Bifunctional transglycosylase second domain MUG2_C PF08593.5 EMC77914.1 - 0.66 10.2 14.9 2.5 8.3 0.0 6.2 7 0 0 7 7 7 0 Meiotically up-regulated glycoproteins C-terminal DUF717 PF05338.7 EMC77914.1 - 2.3 8.2 5.7 7 6.6 0.1 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF717) Septin PF00735.13 EMC77915.1 - 2e-120 401.0 0.0 2.6e-120 400.7 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMC77915.1 - 4e-07 29.9 0.0 7.5e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC77915.1 - 0.00015 21.2 0.0 0.0018 17.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMC77915.1 - 0.00016 20.8 0.2 0.0004 19.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMC77915.1 - 0.00017 20.7 0.6 0.00038 19.6 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EMC77915.1 - 0.00023 21.0 1.9 0.027 14.3 0.0 2.8 2 1 1 3 3 3 1 Dynamin family Ras PF00071.17 EMC77915.1 - 0.00048 19.5 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.1 EMC77915.1 - 0.004 17.2 0.0 0.015 15.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain HrpB7 PF09486.5 EMC77915.1 - 0.0041 17.0 1.2 0.0073 16.2 0.8 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) AAA_10 PF12846.2 EMC77915.1 - 0.0051 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EMC77915.1 - 0.0072 16.6 0.1 0.019 15.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EMC77915.1 - 0.014 15.9 0.0 0.048 14.1 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein AAA_29 PF13555.1 EMC77915.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMC77915.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EMC77915.1 - 0.064 12.9 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 EMC77915.1 - 0.088 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EMC77915.1 - 1 9.6 4.2 12 6.1 2.9 2.2 1 1 0 1 1 1 0 AAA domain UPF0258 PF06789.7 EMC77916.1 - 0.018 15.1 0.4 0.019 15.0 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Collagen PF01391.13 EMC77917.1 - 7.6e-18 63.8 125.7 0.0011 18.5 21.6 5.7 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Bcl-2 PF00452.14 EMC77918.1 - 2.8e-29 101.1 0.1 7.1e-29 99.9 0.0 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family DAGK_cat PF00781.19 EMC77919.1 - 8.8e-31 106.0 0.0 1.3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.14 EMC77919.1 - 1.4e-23 83.8 0.2 2.5e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.17 EMC77919.1 - 1.1e-22 79.4 29.4 2.4e-11 43.1 8.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EMC77919.1 - 1.7 8.7 20.8 3.5 7.7 4.9 2.8 2 0 0 2 2 2 0 C1-like domain IncA PF04156.9 EMC77920.1 - 1.1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 IncA protein Shisa PF13908.1 EMC77920.1 - 4.7e-05 23.6 0.4 5e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Corona_S2 PF01601.11 EMC77920.1 - 0.00035 18.8 2.3 0.0005 18.3 1.6 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Rhabdo_glycop PF00974.13 EMC77920.1 - 0.0051 15.0 0.2 0.0061 14.8 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein TMEM154 PF15102.1 EMC77920.1 - 0.0087 15.7 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Orthoreo_P10 PF07204.6 EMC77920.1 - 0.015 15.0 0.5 0.024 14.3 0.4 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.1 EMC77920.1 - 0.016 15.5 0.3 0.032 14.6 0.2 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EMC77920.1 - 0.032 13.0 0.1 0.041 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM51 PF15345.1 EMC77920.1 - 0.048 13.3 0.1 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Cellulose_synt PF03552.9 EMC77920.1 - 0.13 10.5 0.6 0.16 10.2 0.4 1.1 1 0 0 1 1 1 0 Cellulose synthase CCER1 PF15482.1 EMC77920.1 - 0.37 10.3 7.9 0.32 10.5 5.0 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Prominin PF05478.6 EMC77920.1 - 0.54 7.7 4.2 0.67 7.4 2.9 1.1 1 0 0 1 1 1 0 Prominin Rad60-SLD PF11976.3 EMC77921.1 - 3.1e-26 90.8 0.0 3.6e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMC77921.1 - 6.6e-13 47.8 0.1 8.1e-13 47.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 EMC77921.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG UQ_con PF00179.21 EMC77922.1 - 3.2e-47 159.4 0.0 3.5e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EPTP PF03736.12 EMC77923.1 - 1.8e-58 193.9 14.9 2.4e-13 49.5 0.2 7.8 7 1 0 7 7 7 7 EPTP domain Laminin_G_3 PF13385.1 EMC77923.1 - 3.1e-07 30.7 0.0 1.2e-06 28.8 0.0 2.0 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EMC77923.1 - 6.7e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EMC77923.1 - 0.0023 17.9 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain DUF1794 PF08768.6 EMC77924.1 - 7.4e-38 129.8 0.0 1.5e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) THAP PF05485.7 EMC77924.1 - 1.4e-14 53.9 0.6 4.3e-14 52.4 0.4 1.8 1 0 0 1 1 1 1 THAP domain DUF4201 PF13870.1 EMC77924.1 - 0.0037 16.7 1.0 0.0081 15.6 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) HrpB7 PF09486.5 EMC77924.1 - 0.041 13.8 0.7 0.2 11.5 0.2 2.2 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Peptidase_C54 PF03416.14 EMC77925.1 - 5.3e-108 360.3 0.0 6.8e-108 360.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 PH PF00169.24 EMC77925.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 PH domain Thymidylate_kin PF02223.12 EMC77926.1 - 8.9e-38 129.5 0.0 1.1e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase ING PF12998.2 EMC77927.1 - 1.4e-28 99.2 2.8 2.2e-28 98.6 1.9 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMC77927.1 - 5.2e-10 38.8 8.3 1e-09 37.9 5.8 1.5 1 0 0 1 1 1 1 PHD-finger RRF PF01765.14 EMC77927.1 - 0.00047 19.6 2.6 0.00068 19.1 1.8 1.2 1 0 0 1 1 1 1 Ribosome recycling factor zf-RING-like PF08746.6 EMC77927.1 - 0.017 15.1 5.3 0.031 14.2 3.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.1 EMC77927.1 - 0.042 14.0 1.7 0.061 13.4 0.3 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain HD_3 PF13023.1 EMC77927.1 - 0.092 12.4 1.4 0.13 11.9 1.0 1.2 1 0 0 1 1 1 0 HD domain Enkurin PF13864.1 EMC77927.1 - 0.27 11.4 4.4 0.59 10.3 3.1 1.5 1 0 0 1 1 1 0 Calmodulin-binding APG6 PF04111.7 EMC77927.1 - 1.2 8.0 6.0 1.5 7.7 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FAM75 PF14650.1 EMC77927.1 - 1.7 7.9 5.1 2.2 7.5 3.6 1.1 1 0 0 1 1 1 0 FAM75 family FAD-oxidase_C PF02913.14 EMC77928.1 - 1.7e-53 181.4 0.0 8.3e-53 179.2 0.0 1.8 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMC77928.1 - 5.9e-35 119.7 0.2 9.4e-35 119.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BNR_2 PF13088.1 EMC77929.1 - 6.6e-31 107.6 0.1 1.4e-27 96.6 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.1 EMC77929.1 - 2.7e-06 26.6 0.0 3.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EMC77929.1 - 4e-05 22.8 2.8 0.89 9.6 0.1 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat L6_membrane PF05805.7 EMC77930.1 - 3.4e-53 180.1 10.0 3.8e-53 179.9 6.9 1.0 1 0 0 1 1 1 1 L6 membrane protein UBX PF00789.15 EMC77931.1 - 5.1e-19 68.1 0.0 9.3e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 EMC77931.1 - 1.1e-12 47.7 0.1 2.2e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EMC77931.1 - 2.1e-08 33.5 0.3 6.1e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 UBA-like domain UBA PF00627.26 EMC77931.1 - 0.019 14.8 0.0 0.34 10.8 0.1 2.8 3 0 0 3 3 3 0 UBA/TS-N domain Thioredox_DsbH PF03190.10 EMC77931.1 - 0.02 14.6 0.3 0.035 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 zf-C3HC4 PF00097.20 EMC77932.1 - 5.8e-07 29.0 14.5 1.3e-06 27.9 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC77932.1 - 7.7e-07 29.0 14.5 1.6e-06 28.0 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC77932.1 - 1.1e-06 28.1 13.6 2e-06 27.3 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77932.1 - 2.2e-06 27.2 12.4 4.4e-06 26.3 8.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC77932.1 - 2.4e-05 24.0 15.9 5.3e-05 23.0 11.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC77932.1 - 0.00029 20.6 17.0 0.00052 19.7 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 EMC77932.1 - 0.00068 19.1 8.8 0.0019 17.7 6.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3811 PF11656.3 EMC77932.1 - 0.0028 17.6 3.7 0.0058 16.6 2.6 1.5 1 0 0 1 1 1 1 YjbD family (DUF3811) zf-RING_UBOX PF13445.1 EMC77932.1 - 0.0059 16.3 12.1 0.0086 15.7 7.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 EMC77932.1 - 0.01 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 U-box domain FliT PF05400.8 EMC77932.1 - 0.027 14.8 13.5 0.051 13.9 9.4 1.4 1 0 0 1 1 1 0 Flagellar protein FliT DUF399 PF04187.8 EMC77932.1 - 0.045 13.2 2.7 0.066 12.7 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 AAA_23 PF13476.1 EMC77932.1 - 0.3 11.3 6.5 0.38 11.0 4.5 1.1 1 0 0 1 1 1 0 AAA domain zf-RING_4 PF14570.1 EMC77932.1 - 0.3 10.6 14.5 2.1 7.9 8.9 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain MADF_DNA_bdg PF10545.4 EMC77932.1 - 0.58 10.3 6.9 0.065 13.4 1.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HSP70 PF00012.15 EMC77932.1 - 0.87 7.4 5.2 1 7.1 3.6 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4168 PF13767.1 EMC77932.1 - 2.2 8.9 7.6 4.3 8.0 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) IncA PF04156.9 EMC77932.1 - 4 6.9 10.8 5.1 6.6 7.5 1.2 1 0 0 1 1 1 0 IncA protein DUF501 PF04417.7 EMC77932.1 - 4.6 7.1 9.6 3.3 7.5 1.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF501) Borrelia_P83 PF05262.6 EMC77932.1 - 5.3 5.1 9.8 6.2 4.9 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-UDP PF14569.1 EMC77932.1 - 5.6 6.7 7.8 20 5.0 5.4 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger WD40 PF00400.27 EMC77933.1 - 6e-22 76.6 0.8 1.2e-05 24.9 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat SPRY PF00622.23 EMC77934.1 - 5.4e-16 58.8 0.0 7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain LRR_8 PF13855.1 EMC77935.1 - 8.2e-50 166.4 53.3 6.8e-10 38.5 0.1 10.1 4 2 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 EMC77935.1 - 2.9e-40 135.2 56.3 7.7e-06 25.4 0.1 12.6 8 3 4 13 13 13 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC77935.1 - 7.7e-24 80.0 59.2 0.021 14.7 0.1 19.8 20 1 0 20 20 20 8 Leucine Rich Repeat LRR_7 PF13504.1 EMC77935.1 - 1.8e-07 30.1 74.1 0.71 10.3 0.0 18.0 19 1 1 20 20 20 5 Leucine rich repeat LRR_6 PF13516.1 EMC77935.1 - 1.3e-05 24.7 63.0 2.6 8.3 0.0 17.2 18 1 0 18 18 18 3 Leucine Rich repeat LRR_5 PF13306.1 EMC77935.1 - 0.00076 19.1 0.1 0.37 10.4 0.1 4.1 4 1 2 6 6 6 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC77935.1 - 0.16 11.5 12.7 0.77 9.2 0.1 4.8 1 1 3 4 4 4 0 Leucine-rich repeat CEP19 PF14933.1 EMC77936.1 - 1.1e-34 120.0 1.4 1.2e-34 119.9 1.0 1.0 1 0 0 1 1 1 1 CEP19-like protein PIG-X PF08320.7 EMC77937.1 - 5.7e-34 117.2 0.0 6.6e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Pkinase PF00069.20 EMC77938.1 - 5.4e-73 245.3 0.0 7.7e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77938.1 - 1.2e-47 162.2 0.0 1.7e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMC77938.1 - 7.6e-24 83.9 0.0 2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EMC77938.1 - 4.7e-09 35.6 0.0 0.00014 20.9 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 EMC77938.1 - 0.00078 19.2 0.0 0.0093 15.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC77938.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gal-3-0_sulfotr PF06990.6 EMC77940.1 - 5.3e-125 417.2 0.7 5.9e-125 417.0 0.5 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 EMC77940.1 - 1.1e-05 25.3 0.0 0.00013 21.7 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase family DUF1220 PF06758.8 EMC77940.1 - 0.095 12.5 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) Transferrin PF00405.12 EMC77941.1 - 8.4e-211 698.7 12.9 3e-111 371.4 0.0 3.0 3 0 0 3 3 3 3 Transferrin Phosphonate-bd PF12974.2 EMC77941.1 - 1.1e-05 24.9 0.0 0.0071 15.7 0.0 2.8 2 1 1 3 3 3 2 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3584 PF12128.3 EMC77941.1 - 0.074 10.3 0.0 0.1 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cys_rich_FGFR PF00839.12 EMC77941.1 - 0.29 11.1 4.4 0.79 9.6 0.2 2.7 2 0 0 2 2 2 0 Cysteine rich repeat SRPRB PF09439.5 EMC77942.1 - 1.2e-68 229.9 0.1 1.4e-68 229.6 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EMC77942.1 - 5.2e-17 61.6 0.0 6.8e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC77942.1 - 2.7e-09 36.7 0.3 7.3e-08 32.0 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC77942.1 - 2.4e-07 30.6 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC77942.1 - 6.6e-06 25.4 0.2 1.6e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 EMC77942.1 - 8.4e-06 25.2 0.0 7.5e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.7 EMC77942.1 - 0.0012 18.0 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC77942.1 - 0.0025 18.3 0.0 0.0042 17.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EMC77942.1 - 0.038 13.8 0.3 0.11 12.2 0.2 1.8 1 1 0 1 1 1 0 Dynamin family DUF3799 PF12684.2 EMC77942.1 - 0.044 13.1 0.1 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) G-alpha PF00503.15 EMC77942.1 - 0.059 12.0 0.3 0.23 10.0 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit OATP PF03137.15 EMC77944.1 - 4e-178 592.8 13.5 4.7e-178 592.6 9.3 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EMC77944.1 - 1.7e-21 76.3 27.8 1.7e-21 76.3 19.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.10 EMC77944.1 - 1.8e-07 30.9 3.4 5.9e-07 29.3 2.4 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC77944.1 - 0.0018 18.2 1.8 0.0052 16.7 1.3 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PUCC PF03209.10 EMC77944.1 - 0.031 12.9 5.2 0.21 10.2 0.1 3.0 3 0 0 3 3 3 0 PUCC protein Angiomotin_C PF12240.3 EMC77945.1 - 8.4e-89 296.4 7.8 8.4e-89 296.4 5.4 2.6 2 0 0 2 2 2 1 Angiomotin C terminal UPF0449 PF15136.1 EMC77945.1 - 3.6 7.8 24.7 0.068 13.3 2.8 4.4 2 1 2 4 4 4 0 Uncharacterised protein family UPF0449 Peptidase_C48 PF02902.14 EMC77946.1 - 1.6e-45 155.3 1.6 1.6e-45 155.3 1.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Hydrolase_like2 PF13246.1 EMC77946.1 - 0.008 16.1 0.1 0.022 14.6 0.1 1.8 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Peptidase_C57 PF03290.8 EMC77946.1 - 0.019 13.4 0.1 2.1 6.7 0.0 2.3 1 1 1 2 2 2 0 Vaccinia virus I7 processing peptidase KH_1 PF00013.24 EMC77947.1 - 9.3e-57 188.5 13.0 2.2e-15 56.0 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 EMC77947.1 - 8.7e-38 127.3 15.5 1.3e-09 37.5 0.2 5.0 5 0 0 5 5 5 4 KH domain KH_2 PF07650.12 EMC77947.1 - 5.3e-17 61.1 8.9 0.0003 20.2 0.1 4.8 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 EMC77947.1 - 2.2e-15 56.0 2.2 0.0013 18.3 0.0 5.1 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.17 EMC77947.1 - 2.8e-08 33.2 0.0 6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.1 EMC77947.1 - 5.8e-07 29.2 4.1 0.29 10.9 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain RRM_5 PF13893.1 EMC77947.1 - 2.2e-06 27.3 0.1 5.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77947.1 - 1.9e-05 24.5 0.0 5.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC77948.1 - 6.2e-23 80.2 0.0 8.1e-23 79.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC77948.1 - 1.3e-17 63.4 0.0 1.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC77948.1 - 2.9e-13 49.4 0.0 3.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC77948.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif LRR_4 PF12799.2 EMC77949.1 - 3.8e-15 55.1 9.4 1.7e-08 33.9 1.3 3.5 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC77949.1 - 2.4e-09 36.7 15.3 3.8e-06 26.5 2.2 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 EMC77949.1 - 5.3e-05 22.8 0.0 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EMC77949.1 - 0.0028 17.5 4.8 1.1 9.4 0.3 4.2 4 0 0 4 4 4 1 Leucine Rich repeat Arg_repressor PF01316.16 EMC77949.1 - 0.028 13.9 0.8 0.068 12.7 0.1 2.1 2 1 0 2 2 2 0 Arginine repressor, DNA binding domain LRR_1 PF00560.28 EMC77949.1 - 0.033 14.1 7.4 3.3 8.1 0.8 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EMC77949.1 - 0.35 11.2 4.6 26 5.6 0.2 4.0 4 0 0 4 4 4 0 Leucine rich repeat PFK PF00365.15 EMC77950.1 - 8.1e-186 615.5 7.8 4.6e-125 416.2 1.2 2.0 2 0 0 2 2 2 2 Phosphofructokinase MHC_I PF00129.13 EMC77951.1 - 3.8e-05 23.1 0.0 5.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 CTDII PF01556.13 EMC77952.1 - 7.8e-30 102.6 3.0 3.3e-25 87.8 0.1 3.5 4 0 0 4 4 4 2 DnaJ C terminal domain DnaJ PF00226.26 EMC77952.1 - 5.3e-29 99.7 1.3 8.1e-29 99.1 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Crystall PF00030.14 EMC77953.1 - 6e-60 199.0 1.8 1.6e-29 101.5 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EMC77953.1 - 4.7e-07 29.4 0.5 0.22 11.2 0.0 3.9 3 1 1 4 4 4 3 Beta/Gamma crystallin PMP22_Claudin PF00822.15 EMC77954.1 - 3.9e-30 104.6 14.3 5.1e-30 104.3 9.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC77954.1 - 4e-16 59.1 11.1 6.3e-16 58.5 7.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF308 PF03729.8 EMC77954.1 - 0.001 18.9 15.8 0.045 13.7 6.1 3.0 3 0 0 3 3 3 2 Short repeat of unknown function (DUF308) Amastin PF07344.6 EMC77954.1 - 0.072 12.6 11.8 0.05 13.2 6.6 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF2530 PF10745.4 EMC77954.1 - 0.18 11.7 1.5 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4064 PF13273.1 EMC77954.1 - 0.22 11.6 13.4 0.25 11.4 4.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DoxX PF07681.7 EMC77954.1 - 0.28 11.6 6.9 0.4 11.1 1.3 2.3 2 0 0 2 2 2 0 DoxX Trp_oprn_chp PF09534.5 EMC77954.1 - 0.6 9.6 4.6 6.2 6.3 3.2 2.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1469 PF07332.6 EMC77954.1 - 1.4 8.6 20.3 0.088 12.5 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) TMEM171 PF15471.1 EMC77954.1 - 6.1 5.5 7.9 15 4.2 5.4 1.7 1 1 0 1 1 1 0 Transmembrane protein family 171 Dzip-like_N PF13815.1 EMC77955.1 - 1.5e-35 121.5 0.0 1.5e-35 121.5 0.0 3.2 2 1 0 2 2 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Atg14 PF10186.4 EMC77955.1 - 0.0014 17.6 9.3 0.0028 16.6 6.5 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EMC77955.1 - 0.012 14.0 1.3 0.021 13.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Vfa1 PF08432.5 EMC77955.1 - 0.22 11.5 4.8 0.1 12.6 1.5 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3373 PF11853.3 EMC77955.1 - 0.25 9.8 2.6 0.37 9.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TBPIP PF07106.8 EMC77955.1 - 0.29 10.6 8.2 0.77 9.2 5.7 1.7 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Peptidase_S49_N PF08496.5 EMC77955.1 - 0.3 10.8 6.7 0.042 13.6 1.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EMP24_GP25L PF01105.19 EMC77955.1 - 0.63 9.7 7.2 0.63 9.7 3.8 1.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD TPR_MLP1_2 PF07926.7 EMC77955.1 - 0.89 9.3 17.7 6 6.6 0.3 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RTBV_P46 PF06216.6 EMC77955.1 - 0.89 8.3 3.6 1.9 7.2 2.5 1.4 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein OmpH PF03938.9 EMC77955.1 - 0.93 9.4 19.9 0.61 10.0 7.8 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIVA PF05103.8 EMC77955.1 - 6.3 6.8 15.4 0.6 10.1 6.5 2.2 2 0 0 2 2 2 0 DivIVA protein Gb3_synth PF04572.7 EMC77956.1 - 1e-45 154.7 1.0 1.5e-45 154.1 0.7 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 EMC77956.1 - 2.9e-20 72.5 0.0 9.2e-20 70.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EMC77956.1 - 0.061 12.4 0.0 0.18 10.9 0.0 1.7 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EMC77956.1 - 0.07 11.6 0.0 0.097 11.1 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Pkinase_Tyr PF07714.12 EMC77957.1 - 8.2e-98 326.5 0.0 1.2e-97 326.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC77957.1 - 2.3e-77 258.8 0.1 4.1e-77 257.9 0.1 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC77957.1 - 3.7e-49 167.2 0.0 5.6e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC77957.1 - 1.4e-31 108.4 3.4 2.5e-15 56.3 0.2 3.8 4 0 0 4 4 4 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC77957.1 - 4.1e-27 94.3 0.0 8e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 EMC77957.1 - 2.2e-21 75.7 0.0 4.9e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC77957.1 - 6.2e-20 70.8 0.0 1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC77957.1 - 2.8e-06 26.8 1.0 2.8e-06 26.8 0.7 2.1 2 0 0 2 2 2 1 GCC2 and GCC3 Interfer-bind PF09294.5 EMC77957.1 - 0.009 16.0 0.0 0.062 13.3 0.0 2.4 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 EMC77957.1 - 0.065 13.0 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 SusE outer membrane protein DAP10 PF07213.6 EMC77957.1 - 0.068 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 DAP10 membrane protein Transglut_core PF01841.14 EMC77958.1 - 0.0026 17.9 0.2 0.015 15.4 0.1 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily Tup_N PF08581.5 EMC77959.1 - 0.0018 18.4 10.9 0.0018 18.4 7.6 7.1 5 3 3 8 8 8 2 Tup N-terminal Strep_SA_rep PF06696.6 EMC77959.1 - 6.8 6.5 12.3 1.4 8.7 0.7 3.6 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Apc13p PF05839.6 EMC77960.1 - 3e-20 71.9 0.3 4.1e-20 71.5 0.2 1.2 1 0 0 1 1 1 1 Apc13p protein Lipase PF00151.14 EMC77961.1 - 9.9e-80 268.2 0.0 1.4e-79 267.6 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 EMC77961.1 - 3.9e-07 30.1 0.1 5.9e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family SNARE_assoc PF09335.6 EMC77962.1 - 8.9e-17 61.4 4.9 8.9e-17 61.4 3.4 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3816 PF12822.2 EMC77962.1 - 0.76 9.6 12.0 43 3.9 8.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Jiraiya PF15038.1 EMC77962.1 - 0.78 9.1 5.8 1.7 8.0 4.0 1.6 1 1 0 1 1 1 0 Jiraiya Pkinase_Tyr PF07714.12 EMC77963.1 - 1.7e-64 217.3 0.0 2.7e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC77963.1 - 5.4e-60 202.7 0.0 9.1e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HAUS-augmin3 PF14932.1 EMC77963.1 - 0.01 15.0 2.0 0.029 13.5 1.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Kinase-like PF14531.1 EMC77963.1 - 0.019 13.9 0.0 0.044 12.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EMC77963.1 - 0.031 13.9 0.0 1.4 8.5 0.0 3.2 4 0 0 4 4 4 0 Phosphotransferase enzyme family IFT57 PF10498.4 EMC77963.1 - 0.2 10.3 5.5 0.066 11.9 1.8 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 ECH PF00378.15 EMC77964.1 - 1e-58 198.3 0.0 1.7e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 EMC77964.1 - 1e-51 175.1 0.2 1.6e-51 174.5 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMC77964.1 - 1.1e-31 109.0 0.0 7.8e-24 83.9 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Peptidase_S49 PF01343.13 EMC77964.1 - 0.00038 20.2 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 NAD_binding_2 PF03446.10 EMC77964.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMC77964.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EMC77964.1 - 0.021 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Vps8 PF12816.2 EMC77966.1 - 4.5e-62 208.8 7.5 2.1e-59 200.0 0.5 3.4 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EMC77966.1 - 1.5e-07 31.0 4.6 0.00016 21.3 0.1 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EMC77966.1 - 0.00028 20.6 8.0 0.00097 18.9 5.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC77966.1 - 0.029 14.4 5.8 0.13 12.2 4.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77966.1 - 1.8 8.3 8.8 6.4 6.5 6.1 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Thioredoxin PF00085.15 EMC77967.1 - 1e-08 34.7 0.0 1.2e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EMC77967.1 - 0.028 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family Arm PF00514.18 EMC77968.1 - 6.4e-20 70.2 23.9 6.9e-05 22.5 0.1 11.0 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC77968.1 - 5e-18 65.1 0.6 0.0058 16.8 0.0 7.5 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.17 EMC77968.1 - 2.8e-11 42.5 13.1 0.043 13.9 0.0 8.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EMC77968.1 - 3.7e-06 27.2 1.6 9.4 6.8 0.0 6.8 5 2 2 7 7 7 1 HEAT-like repeat V-ATPase_H_C PF11698.3 EMC77968.1 - 9.3e-05 22.3 7.9 2.3 8.1 0.0 5.2 3 1 1 5 5 5 2 V-ATPase subunit H ParcG PF10274.4 EMC77968.1 - 0.022 14.6 3.2 0.72 9.7 0.2 3.6 2 1 0 3 3 3 0 Parkin co-regulated protein DBR1 PF05011.8 EMC77969.1 - 2.2e-39 134.6 0.8 4e-39 133.7 0.6 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EMC77969.1 - 1.3e-05 24.7 0.2 2.5e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_binding PF10199.4 EMC77969.1 - 0.0016 18.7 1.8 0.01 16.1 1.3 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 EF-hand_7 PF13499.1 EMC77970.1 - 8e-20 70.7 4.3 7.7e-17 61.1 0.8 3.8 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC77970.1 - 1e-05 24.6 0.2 0.0013 17.9 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.27 EMC77970.1 - 2.7e-05 23.1 0.6 0.037 13.3 0.0 4.2 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.1 EMC77970.1 - 5.5e-05 22.7 2.6 0.17 11.8 0.0 4.8 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.1 EMC77970.1 - 0.00052 19.5 0.2 2.6 7.7 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC77970.1 - 0.017 15.1 1.0 8 6.5 0.0 2.7 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4187 PF13821.1 EMC77970.1 - 0.047 13.2 0.7 0.12 11.9 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Carboxyl_trans PF01039.17 EMC77971.1 - 7.9e-191 634.6 0.0 9.5e-191 634.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EMC77971.1 - 0.0099 15.0 0.2 0.048 12.8 0.0 2.0 2 1 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) STAG PF08514.6 EMC77972.1 - 1.5e-47 160.1 1.0 3.8e-47 158.8 0.1 2.2 2 0 0 2 2 2 1 STAG domain Prp18 PF02840.10 EMC77972.1 - 0.048 13.4 3.1 0.16 11.8 0.4 2.8 2 0 0 2 2 2 0 Prp18 domain EamA PF00892.15 EMC77973.1 - 7.9e-17 61.4 27.6 2.3e-09 37.3 9.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EMC77973.1 - 0.0072 15.2 18.4 0.014 14.3 12.6 1.5 1 1 0 1 1 1 1 UAA transporter family Xlink PF00193.12 EMC77974.1 - 4.2e-72 238.3 0.4 1.7e-36 124.1 0.0 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 EMC77974.1 - 5.6e-13 48.7 0.0 1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC77974.1 - 3.2e-05 23.6 0.0 7.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Foamy_BEL PF03274.9 EMC77974.1 - 0.00043 19.5 0.0 0.00071 18.8 0.0 1.3 1 0 0 1 1 1 1 Foamy virus BEL 1/2 protein Ig_2 PF13895.1 EMC77974.1 - 0.0016 18.4 0.0 0.0039 17.2 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC77974.1 - 0.028 14.5 0.3 0.077 13.1 0.2 1.8 1 1 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.1 EMC77974.1 - 0.085 13.3 0.1 0.41 11.1 0.1 2.3 1 1 0 1 1 1 0 Immunoglobulin domain Mab-21 PF03281.9 EMC77975.1 - 6e-13 48.5 1.1 2.5e-12 46.5 1.4 1.5 2 0 0 2 2 2 1 Mab-21 protein F5_F8_type_C PF00754.20 EMC77976.1 - 1.1e-64 215.9 7.0 6.3e-34 116.5 0.7 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.22 EMC77976.1 - 2.3e-13 49.7 24.6 1.7e-08 34.2 5.3 2.7 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.8 EMC77976.1 - 4.6e-06 26.6 22.4 0.0097 16.0 4.9 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EMC77976.1 - 0.00037 20.3 10.3 0.017 15.1 1.1 2.8 2 0 0 2 2 2 2 Human growth factor-like EGF DUF1438 PF07270.6 EMC77976.1 - 0.019 14.8 0.2 9 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) EGF_3 PF12947.2 EMC77976.1 - 1.1 9.2 17.3 1 9.3 2.7 2.6 1 1 1 2 2 2 0 EGF domain COX7C PF02935.11 EMC77977.1 - 2.8e-29 100.7 0.1 3e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc PDR_CDR PF06422.7 EMC77977.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 CDR ABC transporter RasGAP PF00616.14 EMC77978.1 - 1.6e-41 142.1 2.0 1.8e-41 142.0 0.6 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase SH2 PF00017.19 EMC77978.1 - 1.5e-23 82.3 0.1 3.3e-21 74.8 0.0 2.8 2 0 0 2 2 2 1 SH2 domain PH PF00169.24 EMC77978.1 - 1.9e-16 60.1 0.1 6.5e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EMC77978.1 - 4.2e-10 38.8 0.0 8.9e-10 37.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain C2 PF00168.25 EMC77978.1 - 1.4e-08 34.4 0.1 3.4e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.1 EMC77978.1 - 1.1e-06 28.0 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EMC77978.1 - 5.3e-05 23.4 0.4 0.00068 19.8 0.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain Cyclin_N PF00134.18 EMC77979.1 - 2.6e-11 43.1 0.1 5.3e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC77979.1 - 0.00045 20.1 0.2 0.028 14.3 0.0 2.7 2 1 1 3 3 3 1 Cyclin, C-terminal domain TLV_coat PF00429.14 EMC77980.1 - 5e-08 31.8 2.7 6.2e-08 31.5 1.9 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC77980.1 - 0.00031 20.3 0.9 0.00049 19.7 0.6 1.4 1 0 0 1 1 1 1 Retroviral envelope protein Sulfate_transp PF00916.15 EMC77981.1 - 1.2e-33 116.3 2.6 1.2e-33 116.3 1.8 1.9 2 1 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 EMC77981.1 - 2.2e-22 78.6 0.0 1.3e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 STAS domain Pkinase PF00069.20 EMC77982.1 - 5e-41 140.5 5.3 1.5e-23 83.3 0.1 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC77982.1 - 8.1e-15 54.5 0.0 4.8e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase NARP1 PF12569.3 EMC77982.1 - 2 7.0 7.7 2.2 6.9 4.5 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 L_HGMIC_fpl PF10242.4 EMC77983.1 - 1.2e-67 227.4 13.6 1.3e-67 227.2 9.4 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.15 EMC77983.1 - 7.6e-07 28.9 9.7 1.1e-06 28.3 6.7 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC77983.1 - 0.77 9.4 15.5 3.7 7.2 10.4 2.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1772 PF08592.6 EMC77983.1 - 4.2 7.0 6.9 13 5.4 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Colipase_C PF02740.9 EMC77984.1 - 3.6e-26 90.6 4.5 3.6e-26 90.6 3.1 1.5 2 0 0 2 2 2 1 Colipase, C-terminal domain Colipase PF01114.13 EMC77984.1 - 1.6e-13 49.8 7.9 1.6e-13 49.8 5.5 1.8 2 0 0 2 2 2 1 Colipase, N-terminal domain Metallothi_Euk2 PF12809.2 EMC77984.1 - 4.1e-06 27.0 11.7 4.6e-06 26.9 8.1 1.1 1 0 0 1 1 1 1 Eukaryotic metallothionein Colipase-like PF15083.1 EMC77984.1 - 0.0053 16.6 5.7 0.006 16.4 3.9 1.1 1 0 0 1 1 1 1 Colipase-like Prokineticin PF06607.6 EMC77984.1 - 2.2 8.4 8.4 5.7 7.1 5.8 1.7 1 1 0 1 1 1 0 Prokineticin Tub PF01167.13 EMC77987.1 - 5.5e-116 385.8 0.0 7.6e-116 385.3 0.0 1.2 1 0 0 1 1 1 1 Tub family TEA PF01285.13 EMC77988.1 - 2.7e-185 616.6 0.0 3.4e-185 616.3 0.0 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Rotamase_2 PF13145.1 EMC77988.1 - 0.00081 20.0 0.0 0.0016 19.0 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Myb_DNA-binding PF00249.26 EMC77988.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain CLAMP PF14769.1 EMC77988.1 - 0.1 12.7 1.9 4.6 7.4 0.7 2.3 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF1690 PF07956.6 EMC77988.1 - 0.12 12.3 2.3 0.28 11.1 0.9 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) FAP PF07174.6 EMC77988.1 - 4 6.6 13.0 6 6.0 9.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Exo_endo_phos PF03372.18 EMC77989.1 - 1.9e-19 70.6 0.0 2.6e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMC77989.1 - 0.0045 16.5 0.0 0.31 10.6 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase ABC2_membrane_4 PF12730.2 EMC77989.1 - 0.041 13.0 0.8 0.079 12.1 0.6 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3995 PF13160.1 EMC77989.1 - 0.13 12.3 4.8 0.34 10.9 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) IncA PF04156.9 EMC77989.1 - 1.1 8.8 5.9 1.9 8.0 4.1 1.3 1 0 0 1 1 1 0 IncA protein DUF3585 PF12130.3 EMC77990.1 - 1.5e-32 112.3 15.3 1.9e-32 112.0 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) MRVI1 PF05781.7 EMC77991.1 - 1.9e-49 168.4 9.7 7.5e-47 159.9 4.7 2.1 2 0 0 2 2 2 2 MRVI1 protein FA_FANCE PF11510.3 EMC77992.1 - 2.1e-59 200.8 11.0 2.3e-59 200.7 7.6 1.0 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE zf-RING_2 PF13639.1 EMC77993.1 - 9.8e-07 28.5 1.4 9.8e-07 28.5 1.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC77993.1 - 2.2e-06 27.2 0.9 5.2e-06 26.0 0.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC77993.1 - 0.00013 21.6 0.7 0.00032 20.3 0.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC77993.1 - 0.00024 21.1 1.3 0.00025 21.0 0.3 1.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC77993.1 - 0.0003 20.7 2.2 0.0003 20.7 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC77993.1 - 0.00032 20.5 2.3 0.00074 19.3 1.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH PF00642.19 EMC77993.1 - 0.0019 17.8 2.4 0.0047 16.5 1.6 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EMC77993.1 - 0.0019 17.8 1.0 0.0019 17.8 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC77993.1 - 0.016 15.0 1.1 0.019 14.7 0.1 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 EMC77993.1 - 0.15 12.1 2.3 0.34 10.9 1.6 1.7 1 0 0 1 1 1 0 zinc-finger zf-RING_UBOX PF13445.1 EMC77993.1 - 0.45 10.2 2.8 0.34 10.6 0.3 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EMC77993.1 - 1.6 8.3 5.9 0.8 9.3 1.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Hormone_recep PF00104.25 EMC77994.1 - 1.3e-28 99.5 0.0 2.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC77994.1 - 2.8e-28 97.9 17.5 5.3e-28 97.0 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-H2C2_2 PF13465.1 EMC77995.1 - 6.2e-42 139.8 43.0 2.8e-09 36.8 0.3 6.5 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC77995.1 - 4.8e-25 86.3 36.4 4.6e-06 26.6 0.2 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC77995.1 - 6.8e-18 63.6 31.2 0.00067 19.8 0.1 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC77995.1 - 4.8e-07 29.7 12.5 0.4 10.9 0.1 5.8 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EMC77995.1 - 0.00023 21.4 0.6 0.00023 21.4 0.4 3.4 3 1 1 4 4 4 1 TRAF-type zinc finger zf-C2H2_6 PF13912.1 EMC77995.1 - 0.028 14.3 0.5 0.028 14.3 0.4 5.1 6 0 0 6 6 6 0 C2H2-type zinc finger CopK PF11525.3 EMC77995.1 - 0.18 11.4 0.1 31 4.2 0.0 2.9 1 1 2 3 3 3 0 Copper resistance protein K zf-met PF12874.2 EMC77995.1 - 0.38 11.0 14.0 2.2 8.5 0.0 5.0 5 0 0 5 5 5 0 Zinc-finger of C2H2 type CCAP PF11105.3 EMC77995.1 - 0.57 9.9 6.1 8.2 6.1 0.5 2.6 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a IBR PF01485.16 EMC77995.1 - 7 6.6 18.4 51 3.8 1.5 3.6 1 1 1 2 2 2 0 IBR domain Ribosomal_L1 PF00687.16 EMC77996.1 - 7e-38 130.1 3.0 7.7e-38 130.0 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.1 EMC77996.1 - 0.11 11.8 0.1 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor Fibrinogen_BP PF08017.6 EMC77997.1 - 0.79 7.8 31.9 1.1 7.4 22.1 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein FXa_inhibition PF14670.1 EMC77998.1 - 2.3e-58 194.0 183.5 5.4e-11 42.4 5.8 12.4 12 2 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC77998.1 - 8.6e-37 124.3 84.3 7e-08 31.9 0.1 11.6 11 0 0 11 11 11 7 Complement Clr-like EGF-like EGF_CA PF07645.10 EMC77998.1 - 8.2e-30 102.5 167.0 4.5e-09 36.1 7.0 11.8 12 0 0 12 12 12 6 Calcium-binding EGF domain GCC2_GCC3 PF07699.8 EMC77998.1 - 9.4e-30 101.9 27.7 5.7e-13 48.2 4.5 6.7 6 1 1 7 7 7 4 GCC2 and GCC3 EGF PF00008.22 EMC77998.1 - 2.8e-20 71.9 138.7 1.6e-06 27.9 5.1 12.0 13 0 0 13 13 13 9 EGF-like domain CUB PF00431.15 EMC77998.1 - 1.4e-18 67.0 0.0 3.8e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 CUB domain EGF_3 PF12947.2 EMC77998.1 - 1.2e-17 63.5 154.5 2.5e-10 40.1 8.2 12.1 12 0 0 12 12 12 8 EGF domain hEGF PF12661.2 EMC77998.1 - 0.029 14.4 0.4 0.029 14.4 0.3 11.2 11 0 0 11 11 11 0 Human growth factor-like EGF Ank PF00023.25 EMC77999.1 - 5.7e-48 158.4 16.0 1.5e-07 30.8 0.3 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 EMC77999.1 - 1.9e-45 153.1 10.8 4.5e-21 74.9 0.5 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC77999.1 - 1e-42 143.7 11.4 1.7e-11 44.2 0.0 5.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC77999.1 - 1.6e-41 139.4 17.0 3.6e-10 39.7 0.7 6.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC77999.1 - 1.4e-40 133.1 6.8 1.3e-06 28.0 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat PID PF00640.18 EMC77999.1 - 1.7e-30 105.8 0.8 4.2e-30 104.5 0.3 1.9 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SAM_1 PF00536.25 EMC77999.1 - 4.5e-23 81.1 0.0 2.7e-12 46.6 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC77999.1 - 1.2e-20 73.1 0.3 7.7e-13 48.0 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PTB PF08416.8 EMC77999.1 - 0.0023 17.8 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 EMC77999.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Chorein_N PF12624.2 EMC78000.1 - 7.5e-12 44.8 0.1 8.8e-10 38.1 0.0 2.7 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter zf-U1 PF06220.7 EMC78001.1 - 1.6e-20 72.3 8.3 2.1e-20 71.9 5.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EMC78001.1 - 0.011 15.7 9.9 0.079 13.1 6.8 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC78001.1 - 1 9.6 5.4 10 6.5 3.8 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Ets PF00178.17 EMC78003.1 - 1.1e-33 115.1 0.5 1.1e-33 115.1 0.3 1.6 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 EMC78003.1 - 8.3e-19 67.1 0.2 1.7e-18 66.1 0.2 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain FCH PF00611.18 EMC78004.1 - 3.9e-21 75.0 0.2 3.9e-21 75.0 0.1 3.1 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMC78004.1 - 1.4e-16 59.7 0.3 2.8e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC78004.1 - 1.1e-14 53.5 0.1 2.2e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC78004.1 - 1e-07 31.3 0.0 2.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PAP_central PF04928.12 EMC78004.1 - 0.19 10.5 3.8 0.41 9.4 2.6 1.6 1 0 0 1 1 1 0 Poly(A) polymerase central domain Laminin_II PF06009.7 EMC78004.1 - 0.87 9.3 7.7 0.31 10.7 2.7 2.1 2 0 0 2 2 2 0 Laminin Domain II LOH1CR12 PF10158.4 EMC78004.1 - 1.7 8.4 9.4 0.82 9.4 4.2 2.1 1 1 0 2 2 2 0 Tumour suppressor protein S10_plectin PF03501.10 EMC78005.1 - 9.7e-46 153.5 0.2 1.2e-45 153.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain 7tm_1 PF00001.16 EMC78007.1 - 4.6e-54 183.2 12.9 6.8e-54 182.7 9.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.4 EMC78007.1 - 4.2e-25 87.1 3.3 1e-24 85.8 2.3 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.4 EMC78007.1 - 7e-14 51.6 14.2 4.5e-13 49.0 9.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 EMC78007.1 - 9.7e-08 31.4 15.4 1.5e-07 30.8 10.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC78007.1 - 1.3e-07 31.0 16.1 1.9e-07 30.4 11.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.8 EMC78007.1 - 6.4e-05 21.9 8.6 0.00083 18.3 1.0 2.2 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) 60KD_IMP PF02096.15 EMC78007.1 - 0.0047 16.6 4.4 0.0054 16.4 2.3 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein DUF2214 PF09980.4 EMC78007.1 - 0.0096 15.6 2.6 0.041 13.6 0.1 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2214) DUF996 PF06195.8 EMC78007.1 - 0.016 15.1 1.1 0.016 15.1 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF4079 PF13301.1 EMC78007.1 - 0.25 11.3 5.5 0.24 11.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) 7TM_GPCR_Srh PF10318.4 EMC78007.1 - 0.37 9.5 23.8 1 8.1 16.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF788 PF05620.6 EMC78007.1 - 0.68 9.7 0.0 0.68 9.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF788) MSC PF09402.5 EMC78008.1 - 2.7e-45 154.5 0.3 4.1e-45 153.9 0.2 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain PV-1 PF06637.6 EMC78008.1 - 0.0049 15.4 0.1 0.0083 14.7 0.1 1.3 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF4094 PF13334.1 EMC78008.1 - 0.015 15.6 0.1 0.05 13.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Post_transc_reg PF13797.1 EMC78008.1 - 0.035 13.6 0.5 0.089 12.4 0.3 1.6 1 0 0 1 1 1 0 Post-transcriptional regulator VirB3 PF05101.8 EMC78008.1 - 0.26 11.2 4.8 2.8 8.0 0.2 2.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein IPK PF03770.11 EMC78009.1 - 5.6e-24 84.8 0.3 7.9e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase TspO_MBR PF03073.10 EMC78012.1 - 3.3e-41 140.2 5.7 3.7e-41 140.0 3.9 1.0 1 0 0 1 1 1 1 TspO/MBR family APOBEC_N PF08210.6 EMC78013.1 - 3.9e-45 153.8 1.5 4.9e-45 153.4 1.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 EMC78013.1 - 1.3e-20 72.5 1.2 2.2e-20 71.7 0.8 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.17 EMC78013.1 - 6.8e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.1 EMC78013.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 MafB19-like deaminase Macro PF01661.16 EMC78014.1 - 6.1e-10 39.0 0.0 8.7e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Macro domain Keratin PF02422.11 EMC78015.1 - 3.8e-30 103.7 16.3 4.5e-30 103.4 11.3 1.1 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC78015.1 - 0.014 15.4 8.8 0.018 15.0 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) zf-Tim10_DDP PF02953.10 EMC78015.1 - 0.16 11.3 0.6 0.27 10.5 0.4 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger 7tm_4 PF13853.1 EMC78016.1 - 1.5e-41 141.5 14.3 1.5e-41 141.5 9.9 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC78016.1 - 3.1e-31 108.4 16.6 4.9e-31 107.7 11.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Stathmin PF00836.14 EMC78017.1 - 1.2e-73 245.3 24.1 1.5e-73 245.0 16.7 1.1 1 0 0 1 1 1 1 Stathmin family HTH_8 PF02954.14 EMC78017.1 - 0.053 13.0 0.7 0.053 13.0 0.5 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family CDC37_N PF03234.9 EMC78017.1 - 0.091 13.0 13.0 0.16 12.3 9.0 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding OS-D PF03392.8 EMC78017.1 - 0.44 10.5 4.9 0.71 9.8 2.0 2.3 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D Fib_alpha PF08702.5 EMC78017.1 - 1.1 9.3 9.7 1.8 8.6 6.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNA_pol_Rpb1_4 PF05000.12 EMC78017.1 - 1.6 8.5 4.2 0.48 10.1 0.6 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 HLH PF00010.21 EMC78018.1 - 2.8e-17 62.1 0.8 4.7e-17 61.4 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC78018.1 - 7e-13 48.0 0.0 1.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Hairy Orange MRP-S35 PF10246.4 EMC78019.1 - 5e-52 174.2 0.0 5.8e-52 174.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.18 EMC78019.1 - 0.00033 20.6 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain TPD52 PF04201.10 EMC78020.1 - 3.7e-69 231.5 8.8 4.4e-69 231.3 6.1 1.1 1 0 0 1 1 1 1 Tumour protein D52 family IncA PF04156.9 EMC78020.1 - 0.001 18.6 4.3 0.0017 18.0 3.0 1.4 1 0 0 1 1 1 1 IncA protein PEP-utilisers_N PF05524.8 EMC78020.1 - 0.0056 16.4 3.1 0.011 15.5 2.2 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Wx5_PLAF3D7 PF09688.5 EMC78020.1 - 0.014 15.3 3.4 0.025 14.5 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) Cob_adeno_trans PF01923.13 EMC78020.1 - 0.023 14.5 0.8 0.033 13.9 0.5 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF4164 PF13747.1 EMC78020.1 - 0.03 14.4 2.4 4.2 7.5 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Occludin_ELL PF07303.8 EMC78020.1 - 0.042 14.5 3.7 0.81 10.4 0.1 2.3 1 1 1 2 2 2 0 Occludin homology domain APG6 PF04111.7 EMC78020.1 - 0.053 12.5 4.8 0.074 12.0 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 RNA_pol_A_CTD PF03118.10 EMC78020.1 - 0.056 12.8 1.3 0.14 11.5 0.9 1.7 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain ERM PF00769.14 EMC78020.1 - 0.067 12.7 8.8 0.082 12.4 6.1 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TBPIP PF07106.8 EMC78020.1 - 0.088 12.3 9.8 0.49 9.9 6.0 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) VASP_tetra PF08776.6 EMC78020.1 - 0.15 11.3 5.0 0.12 11.7 2.1 1.7 2 0 0 2 2 2 0 VASP tetramerisation domain WXG100 PF06013.7 EMC78020.1 - 0.16 12.0 6.4 1.7 8.6 0.2 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Ada3 PF10198.4 EMC78020.1 - 0.17 11.6 4.5 0.3 10.8 3.1 1.4 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 MitMem_reg PF13012.1 EMC78020.1 - 0.17 11.9 3.4 4.1 7.5 1.3 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function AAA_13 PF13166.1 EMC78020.1 - 0.19 10.1 9.7 0.98 7.8 6.7 1.7 1 1 0 1 1 1 0 AAA domain Talin_middle PF09141.5 EMC78020.1 - 0.23 11.1 5.1 0.23 11.1 2.6 1.6 1 1 1 2 2 2 0 Talin, middle domain SlyX PF04102.7 EMC78020.1 - 0.23 11.8 6.8 2.4 8.6 3.8 2.6 1 1 1 2 2 2 0 SlyX RsbRD_N PF14361.1 EMC78020.1 - 0.29 11.5 4.3 4.1 7.8 0.3 2.7 2 1 1 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain GvpK PF05121.7 EMC78020.1 - 0.3 10.9 4.0 1 9.2 2.8 1.9 1 1 0 1 1 1 0 Gas vesicle protein K Carbpep_Y_N PF05388.6 EMC78020.1 - 0.47 10.6 2.7 1.8 8.7 1.9 2.0 1 1 0 1 1 1 0 Carboxypeptidase Y pro-peptide Prefoldin_2 PF01920.15 EMC78020.1 - 0.73 9.6 11.5 2.2 8.0 5.1 2.4 1 1 1 2 2 2 0 Prefoldin subunit Siah-Interact_N PF09032.6 EMC78020.1 - 0.74 9.9 8.4 0.13 12.3 2.1 2.2 1 1 1 2 2 2 0 Siah interacting protein, N terminal OmpH PF03938.9 EMC78020.1 - 0.9 9.4 9.6 1.8 8.4 6.3 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Uds1 PF15456.1 EMC78020.1 - 1.1 9.3 9.2 3.1 7.8 6.4 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Macoilin PF09726.4 EMC78020.1 - 1.2 7.3 9.8 0.85 7.8 5.9 1.3 1 1 0 1 1 1 0 Transmembrane protein DUF724 PF05266.9 EMC78020.1 - 1.3 8.5 8.5 1.7 8.2 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1192 PF06698.6 EMC78020.1 - 1.7 8.4 5.6 3.6 7.4 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Vfa1 PF08432.5 EMC78020.1 - 2.1 8.3 6.2 3.1 7.7 4.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Med9 PF07544.8 EMC78020.1 - 3.2 7.5 7.8 1.1 9.0 2.1 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.6 EMC78020.1 - 5.9 6.3 11.5 12 5.3 7.9 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF3762 PF12591.3 EMC78021.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3762) T4SS-DNA_transf PF02534.9 EMC78021.1 - 0.085 11.4 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer zf-C2H2 PF00096.21 EMC78022.1 - 0.061 13.6 1.5 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type COMPASS-Shg1 PF05205.7 EMC78023.1 - 6.8e-14 52.0 0.0 7.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 RRM_1 PF00076.17 EMC78024.1 - 7.2e-11 41.5 0.0 8.7e-08 31.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78024.1 - 2.7e-07 30.4 0.0 6.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcyon PF06387.6 EMC78025.1 - 3.8e-89 296.9 0.1 4.4e-89 296.7 0.1 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) Homeobox PF00046.24 EMC78026.1 - 5.2e-17 61.1 3.1 7.6e-17 60.6 2.2 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC78026.1 - 0.12 11.4 0.8 0.38 9.8 0.1 2.0 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez 7tm_1 PF00001.16 EMC78027.1 - 7.3e-80 267.8 19.6 9.1e-80 267.4 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78027.1 - 3.3e-09 36.2 18.4 5.8e-09 35.4 12.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC78027.1 - 1.3e-07 31.0 15.9 1.3e-07 31.0 11.0 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Mtc PF03820.12 EMC78028.1 - 1.2e-146 487.2 0.0 1.4e-146 487.0 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Kinesin PF00225.18 EMC78029.1 - 2.4e-101 338.8 0.1 2.4e-101 338.8 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain DUF2422 PF10337.4 EMC78029.1 - 0.049 12.4 10.5 0.086 11.6 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) OmpH PF03938.9 EMC78029.1 - 2.1 8.2 36.7 5.2 6.9 0.1 3.5 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Bromodomain PF00439.20 EMC78030.1 - 1.1e-47 159.8 3.0 4e-23 81.1 0.1 3.1 3 0 0 3 3 3 2 Bromodomain DUF2209 PF09974.4 EMC78030.1 - 0.56 10.2 4.9 0.6 10.1 1.8 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Ribosomal_L7Ae PF01248.21 EMC78031.1 - 3.9e-23 80.7 0.1 4.5e-23 80.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_transf_7C PF02709.9 EMC78032.1 - 1.1e-27 95.3 0.1 1.7e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC78032.1 - 0.0027 16.8 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.1 EMC78032.1 - 0.061 12.6 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Lectin_leg-like PF03388.8 EMC78033.1 - 1.2e-91 305.9 0.0 1.4e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EMC78033.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 Legume lectin domain Arf PF00025.16 EMC78034.1 - 1.2e-67 226.5 0.0 1.3e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC78034.1 - 1.7e-12 47.0 0.0 2e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC78034.1 - 1.8e-12 46.8 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC78034.1 - 3.9e-11 43.4 0.0 5.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EMC78034.1 - 5e-10 38.9 0.0 6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC78034.1 - 1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EMC78034.1 - 1.8e-08 33.5 0.1 2e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 EMC78034.1 - 2.1e-07 30.5 0.0 7e-05 22.3 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMC78034.1 - 0.0037 16.7 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EMC78034.1 - 0.017 15.4 0.1 0.033 14.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Peptidase_M17_N PF02789.12 EMC78034.1 - 0.024 14.3 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain FeoB_N PF02421.13 EMC78034.1 - 0.052 12.8 0.1 0.14 11.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 EMC78034.1 - 0.11 11.9 0.1 13 5.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EMC78034.1 - 0.11 12.4 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EMC78034.1 - 0.13 11.9 0.2 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Na_Pi_cotrans PF02690.10 EMC78035.1 - 1.6e-59 199.7 27.3 4e-32 110.8 5.6 2.9 2 1 1 3 3 3 2 Na+/Pi-cotransporter Pkinase PF00069.20 EMC78036.1 - 8.2e-63 211.9 0.0 1.4e-62 211.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78036.1 - 2.7e-35 121.7 0.0 3.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EMC78036.1 - 2.9e-20 72.5 0.5 9.6e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 EMC78036.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cofilin_ADF PF00241.15 EMC78038.1 - 1.9e-14 53.6 0.0 4.6e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein DUF3523 PF12037.3 EMC78038.1 - 7.9 5.3 34.5 11 4.9 23.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DEAD PF00270.24 EMC78039.1 - 4e-42 143.5 0.0 3.3e-40 137.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC78039.1 - 1.1e-28 98.8 0.0 9.3e-28 95.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EMC78039.1 - 0.0033 17.3 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain zf-CCHC PF00098.18 EMC78039.1 - 0.0081 16.0 2.0 0.015 15.1 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF1253 PF06862.7 EMC78039.1 - 0.018 13.4 0.0 0.13 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 EMC78039.1 - 0.027 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Helicase_C_4 PF13871.1 EMC78039.1 - 0.037 13.4 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase_C-like zf-CCHC_4 PF14392.1 EMC78039.1 - 0.22 11.2 1.3 0.47 10.1 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3886 PF13025.1 EMC78039.1 - 2.2 8.3 15.5 5.8 6.9 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) PRELI PF04707.9 EMC78041.1 - 2.6e-39 134.3 0.2 3.7e-39 133.8 0.1 1.2 1 0 0 1 1 1 1 PRELI-like family Trigger_C PF05698.9 EMC78042.1 - 0.15 11.8 0.1 0.17 11.6 0.0 1.0 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Pkinase_Tyr PF07714.12 EMC78044.1 - 2.4e-103 344.7 0.0 3.3e-103 344.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC78044.1 - 2.2e-47 161.4 0.0 3.2e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 EMC78044.1 - 6.9e-32 109.1 0.0 1.7e-14 53.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78044.1 - 2.3e-23 82.1 0.0 2.7e-08 33.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC78044.1 - 2.4e-18 66.3 0.1 1.4e-07 31.9 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC78044.1 - 1.2e-16 60.5 0.2 3.2e-06 27.1 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC78044.1 - 9.4e-13 48.0 0.1 0.0036 17.1 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC78044.1 - 0.026 14.4 0.0 0.17 11.8 0.0 2.2 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC78044.1 - 0.056 11.7 0.0 2.7 6.1 0.0 2.9 3 1 1 4 4 4 0 Alphaherpesvirus glycoprotein E APH PF01636.18 EMC78044.1 - 0.066 12.9 0.0 0.65 9.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC78044.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like UIM PF02809.15 EMC78045.1 - 0.004 16.5 12.1 0.0087 15.5 2.1 3.3 2 0 0 2 2 2 2 Ubiquitin interaction motif Hexokinase_2 PF03727.11 EMC78046.1 - 5.8e-164 543.0 0.6 2.3e-95 318.4 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EMC78046.1 - 2.2e-131 435.4 0.2 3.6e-74 248.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase ZU5 PF00791.15 EMC78047.1 - 1.2e-33 114.8 0.0 2.2e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 ZU5 domain I-set PF07679.11 EMC78047.1 - 5.9e-12 45.2 0.0 3.1e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Death PF00531.17 EMC78047.1 - 6.2e-12 45.1 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Death domain TSP_1 PF00090.14 EMC78047.1 - 3e-09 36.8 36.9 1.5e-07 31.3 9.5 2.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ig_2 PF13895.1 EMC78047.1 - 1.6e-08 34.5 0.1 5.8e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC78047.1 - 0.00031 21.1 0.0 0.003 18.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain IF4E PF01652.13 EMC78048.1 - 5.9e-59 198.2 1.5 6.6e-59 198.1 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Synuclein PF01387.12 EMC78049.1 - 1.9e-19 69.8 5.3 3e-19 69.2 3.7 1.3 1 1 0 1 1 1 1 Synuclein ELFV_dehydrog PF00208.16 EMC78050.1 - 5.5e-51 173.4 0.0 2.6e-49 168.0 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EMC78050.1 - 1.5e-30 105.4 0.0 3.3e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Cadherin PF00028.12 EMC78052.1 - 1.8e-98 322.9 17.6 1.3e-16 60.6 0.1 9.6 9 1 0 9 9 9 9 Cadherin domain Cadherin_2 PF08266.7 EMC78052.1 - 1.1e-11 44.0 0.0 0.13 11.8 0.0 5.4 5 0 0 5 5 5 4 Cadherin-like UBA_4 PF14555.1 EMC78053.1 - 7.8e-08 31.7 0.3 4.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 EMC78053.1 - 9.5e-07 28.7 0.1 3.6e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 EMC78053.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain NARP1 PF12569.3 EMC78053.1 - 0.031 13.0 10.2 0.048 12.4 7.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_23 PF13476.1 EMC78053.1 - 0.046 14.0 4.7 0.073 13.3 3.3 1.4 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.9 EMC78053.1 - 0.66 8.7 21.7 0.99 8.1 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1510 PF07423.6 EMC78053.1 - 1.2 8.4 11.3 1.9 7.7 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Caldesmon PF02029.10 EMC78053.1 - 6.9 4.9 23.6 9.5 4.5 16.4 1.1 1 0 0 1 1 1 0 Caldesmon HIG_1_N PF04588.8 EMC78054.1 - 4.5e-19 67.9 3.2 5.8e-19 67.5 2.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Nop16 PF09420.5 EMC78055.1 - 6.5e-33 114.1 1.6 7.4e-33 113.9 1.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ORF6C PF10552.4 EMC78055.1 - 0.0047 16.6 1.0 0.006 16.2 0.7 1.3 1 0 0 1 1 1 1 ORF6C domain Arf PF00025.16 EMC78056.1 - 4.8e-39 133.3 0.0 6e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMC78056.1 - 6.7e-10 39.5 0.0 9.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EMC78056.1 - 3.1e-09 36.3 0.0 3.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EMC78056.1 - 7e-07 28.7 0.0 8.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC78056.1 - 7.4e-06 25.3 0.0 9.5e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 EMC78056.1 - 0.0003 20.5 0.1 0.4 10.3 0.0 2.3 2 1 0 2 2 2 2 NACHT domain GTP_EFTU PF00009.22 EMC78056.1 - 0.00035 20.0 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EMC78056.1 - 0.00041 19.1 0.0 0.0019 16.9 0.0 1.8 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EMC78056.1 - 0.005 16.7 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC78056.1 - 0.012 15.5 5.1 0.14 12.1 0.1 2.4 2 1 1 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 EMC78056.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter P33MONOX PF15302.1 EMC78057.1 - 3.5e-148 492.9 9.0 3.9e-148 492.8 6.2 1.0 1 0 0 1 1 1 1 P33 mono-oxygenase WD40 PF00400.27 EMC78059.1 - 8.8e-33 111.0 9.9 1.7e-09 37.1 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC78059.1 - 1.2e-13 51.2 9.5 6.9e-07 29.1 0.3 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EMC78059.1 - 9.9e-06 24.5 0.1 0.00064 18.6 0.2 2.2 1 1 1 2 2 2 2 Coatomer WD associated region PD40 PF07676.7 EMC78059.1 - 0.00011 21.7 0.0 0.017 14.7 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EMC78059.1 - 0.0019 16.4 0.1 0.004 15.3 0.0 1.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMC78059.1 - 0.0019 16.5 0.0 0.011 14.0 0.0 1.8 1 1 1 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EMC78059.1 - 0.0023 17.4 0.1 0.54 9.6 0.1 2.1 1 1 0 2 2 2 1 PQQ-like domain DUF4613 PF15390.1 EMC78059.1 - 0.017 13.3 1.0 0.022 12.9 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) Me-amine-dh_H PF06433.6 EMC78059.1 - 0.018 13.6 0.0 1.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) YjbR PF04237.8 EMC78059.1 - 0.068 13.5 0.1 9 6.7 0.0 3.2 2 1 2 4 4 4 0 YjbR Peptidase_S9_N PF02897.10 EMC78059.1 - 0.17 10.4 4.5 2.2 6.7 0.2 2.8 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain 7tm_1 PF00001.16 EMC78060.1 - 1.5e-70 237.2 16.6 2e-70 236.8 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78060.1 - 9.6e-13 47.8 12.4 1.2e-12 47.5 8.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC78060.1 - 0.0021 17.2 14.7 0.0037 16.4 10.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Kazal_1 PF00050.16 EMC78061.1 - 4.5e-15 55.3 3.2 5.3e-15 55.1 2.2 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC78061.1 - 3.1e-10 39.8 1.7 4.5e-10 39.3 1.2 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC78062.1 - 1.1e-120 393.5 73.4 5.2e-19 68.0 3.5 7.1 7 0 0 7 7 7 7 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC78062.1 - 6.2e-71 234.0 69.2 1.5e-11 43.9 1.7 7.3 7 0 0 7 7 7 7 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC78063.1 - 2e-44 149.3 29.1 3.4e-18 65.4 4.9 3.1 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC78063.1 - 1.6e-28 98.3 26.7 5.2e-11 42.2 4.1 3.3 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain DUF393 PF04134.7 EMC78063.1 - 0.5 11.4 6.6 23 6.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF393 Kazal_1 PF00050.16 EMC78064.1 - 4.1e-11 42.7 4.3 5.5e-11 42.3 3.0 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC78064.1 - 2.7e-08 33.5 3.6 3.7e-08 33.1 2.5 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC78065.1 - 2.9e-17 62.4 4.1 3.2e-17 62.2 2.9 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC78065.1 - 1.4e-14 53.7 3.0 1.8e-14 53.3 2.1 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain NIF PF03031.13 EMC78066.1 - 3.1e-29 101.6 0.2 5e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EMC78066.1 - 1.6e-06 27.3 0.1 3.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EMC78066.1 - 0.014 15.6 0.1 0.037 14.2 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain Med22 PF06179.7 EMC78066.1 - 0.2 11.7 1.2 8.2 6.5 0.2 2.4 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex TIG PF01833.19 EMC78068.1 - 7.2e-13 48.3 0.2 7.2e-13 48.3 0.2 2.6 2 0 0 2 2 2 1 IPT/TIG domain HLH PF00010.21 EMC78068.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain ENTH PF01417.15 EMC78069.1 - 8.7e-46 154.8 0.2 1.8e-45 153.8 0.0 1.6 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.11 EMC78069.1 - 1.7e-05 23.7 0.0 2.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain LSM PF01423.17 EMC78070.1 - 6.1e-12 44.9 0.0 2.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 LSM domain Thg1C PF14413.1 EMC78071.1 - 6.9e-54 180.6 0.6 1.1e-53 180.0 0.4 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EMC78071.1 - 1.9e-44 150.5 0.0 2.7e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase HMG_box PF00505.14 EMC78072.1 - 8.8e-23 80.3 1.3 1.6e-22 79.5 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC78072.1 - 5.4e-11 42.6 0.3 8.5e-11 42.0 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain Reprolysin PF01421.14 EMC78073.1 - 4.2e-62 209.3 0.0 4.2e-62 209.3 0.0 1.7 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC78073.1 - 1.3e-32 112.2 6.6 1.3e-32 112.2 4.6 3.7 3 1 2 5 5 2 1 ADAM cysteine-rich Reprolysin_5 PF13688.1 EMC78073.1 - 6e-24 85.0 0.5 2e-23 83.3 0.3 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.18 EMC78073.1 - 1e-23 83.3 27.1 1e-23 83.3 18.8 4.6 3 1 1 4 4 2 1 Disintegrin Pep_M12B_propep PF01562.14 EMC78073.1 - 9.7e-22 77.1 0.3 1.6e-21 76.4 0.2 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.1 EMC78073.1 - 2.4e-19 70.0 0.2 8.2e-19 68.3 0.1 2.0 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC78073.1 - 6e-15 55.7 0.1 6e-15 55.7 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC78073.1 - 2.7e-13 49.9 0.9 3.6e-13 49.5 0.1 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 EMC78073.1 - 0.0024 18.0 15.3 0.0024 18.0 10.6 6.0 5 1 0 5 5 2 1 EGF-like domain Peptidase_M43 PF05572.8 EMC78073.1 - 0.052 13.1 0.2 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.4 EMC78073.1 - 0.078 11.8 0.3 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 EMC78073.1 - 0.096 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin Mg_trans_NIPA PF05653.9 EMC78074.1 - 2.4e-128 427.3 13.7 2.8e-128 427.1 9.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMC78074.1 - 5.2e-09 36.3 0.8 5.2e-09 36.3 0.5 3.4 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC78074.1 - 5.9e-07 29.5 5.0 5.9e-07 29.5 3.4 3.5 3 1 1 4 4 4 1 EamA-like transporter family K1 PF02960.9 EMC78074.1 - 1.4 8.9 9.1 0.7 9.9 2.8 2.6 1 1 2 3 3 3 0 K1 glycoprotein fn3 PF00041.16 EMC78075.1 - 4.7e-05 23.4 0.1 7.6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Pkinase_Tyr PF07714.12 EMC78076.1 - 7.7e-92 307.0 0.0 1.1e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC78076.1 - 5.3e-50 169.9 0.0 9.6e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC78076.1 - 6.6e-21 73.9 0.0 1.4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC78076.1 - 8.8e-16 57.0 0.3 1.9e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain BTK PF00779.14 EMC78076.1 - 1.4e-13 50.1 3.2 2.5e-13 49.3 2.2 1.4 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.1 EMC78076.1 - 8.9e-13 47.6 0.3 2.1e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC78076.1 - 1.4e-11 44.4 1.0 3.5e-11 43.2 0.7 1.7 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 EMC78076.1 - 6.4e-09 35.1 0.0 1.5e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC78076.1 - 0.00011 22.2 0.2 0.00029 20.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain PH_8 PF15409.1 EMC78076.1 - 0.00085 19.3 0.5 0.0033 17.4 0.3 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EMC78076.1 - 0.016 15.4 1.9 0.07 13.3 0.7 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain Kinase-like PF14531.1 EMC78076.1 - 0.019 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Med7 PF05983.6 EMC78077.1 - 9e-49 165.3 4.4 1.1e-48 165.0 3.0 1.1 1 0 0 1 1 1 1 MED7 protein Katanin_con80 PF13925.1 EMC78077.1 - 0.0025 17.5 1.0 0.0037 17.0 0.7 1.1 1 0 0 1 1 1 1 con80 domain of Katanin V-set PF07686.12 EMC78078.1 - 6.3e-14 51.8 0.1 1.2e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC78078.1 - 0.0022 18.0 0.0 0.01 15.9 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 EMC78078.1 - 0.0022 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain DUF4448 PF14610.1 EMC78078.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ig_2 PF13895.1 EMC78078.1 - 0.027 14.5 0.4 0.087 12.9 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.1 EMC78078.1 - 0.074 13.5 0.6 0.34 11.4 0.1 2.2 2 0 0 2 2 2 0 Immunoglobulin domain zf-RING_6 PF14835.1 EMC78078.1 - 0.1 12.4 0.1 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Sarcoglycan_1 PF04790.8 EMC78079.1 - 1.1e-103 345.9 0.0 1.3e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 EMC78079.1 - 0.00084 18.9 0.0 0.0066 16.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) Ribosomal_L22 PF00237.14 EMC78080.1 - 2.8e-22 78.6 0.2 4.2e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CAF1 PF04857.15 EMC78081.1 - 2.8e-71 239.9 0.2 4.2e-71 239.3 0.1 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease FA_hydroxylase PF04116.8 EMC78082.1 - 5.2e-14 52.6 18.8 5.2e-14 52.6 13.0 2.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily La PF05383.12 EMC78084.1 - 7.2e-24 83.3 0.3 2.2e-23 81.7 0.1 2.0 2 0 0 2 2 2 1 La domain zf-SAP30 PF13866.1 EMC78086.1 - 2e-38 129.8 0.6 3.8e-38 128.9 0.4 1.4 1 0 0 1 1 1 1 SAP30 zinc-finger SAP30_Sin3_bdg PF13867.1 EMC78086.1 - 4e-25 87.4 0.2 9.5e-25 86.2 0.1 1.7 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Glycos_transf_2 PF00535.21 EMC78087.1 - 2e-30 105.7 0.0 3.9e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC78087.1 - 1e-25 90.1 0.6 1.5e-25 89.6 0.4 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EMC78087.1 - 2.6e-08 33.1 0.1 6.1e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC78087.1 - 2.7e-07 29.9 0.0 4e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 EMC78087.1 - 0.00035 20.9 0.0 0.24 11.7 0.0 2.6 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like rve_2 PF13333.1 EMC78087.1 - 0.016 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain V-set PF07686.12 EMC78088.1 - 4.5e-07 29.7 0.1 2.7e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC78088.1 - 4.6e-06 26.4 0.0 8.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78088.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC78088.1 - 0.012 16.0 0.0 0.043 14.3 0.0 2.0 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.20 EMC78088.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain DUF4446 PF14584.1 EMC78088.1 - 0.067 13.0 0.4 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Corona_3 PF04694.7 EMC78088.1 - 0.086 12.7 0.2 0.32 10.9 0.2 2.0 1 1 0 1 1 1 0 Coronavirus ORF3 protein DUF719 PF05334.8 EMC78089.1 - 3.7e-66 222.6 1.5 3.7e-66 222.6 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF719) DUF2398 PF09661.5 EMC78089.1 - 0.034 12.8 2.1 3.9 6.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2398) DUF755 PF05501.6 EMC78090.1 - 0.019 15.0 21.8 0.022 14.7 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TFIIF_alpha PF05793.7 EMC78090.1 - 5.5 5.2 43.6 6.2 5.0 30.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LON PF02190.11 EMC78091.1 - 1.3e-23 83.7 0.0 2.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EMC78091.1 - 5.7e-13 48.6 32.9 1.2e-07 31.6 10.3 3.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC78091.1 - 2.1e-12 46.5 28.0 4.4e-06 26.3 4.4 2.8 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC78091.1 - 2.1e-11 43.3 23.8 1e-07 31.4 7.0 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EMC78091.1 - 3.8e-11 42.4 1.1 1e-05 25.1 0.3 3.1 2 1 1 3 3 3 2 TPR repeat zf-C3HC4 PF00097.20 EMC78091.1 - 2.3e-10 39.9 32.4 1.1e-06 28.2 9.7 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC78091.1 - 1.1e-09 38.0 28.7 2.9e-05 23.8 5.3 3.4 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC78091.1 - 2.9e-08 33.4 41.1 1.9e-07 30.7 9.8 3.5 3 1 1 4 4 4 2 Ring finger domain TPR_2 PF07719.12 EMC78091.1 - 1.5e-07 30.7 1.6 0.096 12.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC78091.1 - 2.4e-07 30.0 0.5 0.02 14.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC78091.1 - 2.1e-06 28.2 2.3 1.6e-05 25.3 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78091.1 - 2.9e-06 27.4 5.0 0.0061 17.0 0.1 4.1 1 1 2 3 3 3 1 Tetratricopeptide repeat zf-RING_6 PF14835.1 EMC78091.1 - 3.8e-05 23.3 21.9 0.016 14.9 4.3 3.2 3 0 0 3 3 3 2 zf-RING of BARD1-type protein TPR_8 PF13181.1 EMC78091.1 - 0.00018 21.0 0.0 0.093 12.5 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC78091.1 - 0.00024 20.8 13.3 0.00052 19.7 0.9 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat zf-RING_UBOX PF13445.1 EMC78091.1 - 0.0011 18.6 7.5 0.0011 18.6 5.2 3.5 3 1 0 3 3 2 2 RING-type zinc-finger Apc3 PF12895.2 EMC78091.1 - 0.0013 18.8 0.7 0.0022 18.0 0.0 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMC78091.1 - 0.0038 17.3 0.2 0.43 10.9 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.12 EMC78091.1 - 0.0084 16.4 4.6 0.065 13.5 0.2 2.6 1 1 1 2 2 2 1 Bacterial transcriptional activator domain U-box PF04564.10 EMC78091.1 - 0.0085 16.0 0.1 0.03 14.2 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-RING_4 PF14570.1 EMC78091.1 - 0.011 15.3 6.1 0.011 15.3 4.2 3.2 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain DUF35_N PF12172.3 EMC78091.1 - 0.026 14.4 0.3 0.026 14.4 0.2 3.6 3 0 0 3 3 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TPR_19 PF14559.1 EMC78091.1 - 0.029 14.7 0.6 0.37 11.1 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC78091.1 - 0.032 14.6 0.4 15 6.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC78091.1 - 0.035 14.0 1.8 15 5.6 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EMC78091.1 - 0.068 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ChAPs PF09295.5 EMC78091.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) zf-rbx1 PF12678.2 EMC78091.1 - 0.48 10.5 18.7 0.034 14.2 4.0 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger Lig_chan PF00060.21 EMC78092.1 - 8.6e-61 203.9 0.1 1.5e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 EMC78092.1 - 8.3e-59 199.1 0.1 1.1e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 EMC78092.1 - 3.4e-26 91.0 0.6 1.2e-25 89.2 0.1 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC78092.1 - 2.2e-25 89.2 0.0 4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF659 PF04937.10 EMC78092.1 - 0.052 13.0 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) 7tm_1 PF00001.16 EMC78093.1 - 3.2e-52 177.2 18.5 4.4e-52 176.7 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78093.1 - 8.9e-11 41.4 16.8 1.8e-10 40.4 11.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 EMC78093.1 - 0.00027 20.1 16.6 0.011 14.9 11.5 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Sigma_reg_N PF13800.1 EMC78093.1 - 0.17 11.9 0.1 0.17 11.9 0.1 4.3 3 1 2 5 5 5 0 Sigma factor regulator N-terminal 7TM_GPCR_Srx PF10328.4 EMC78093.1 - 0.21 10.6 25.7 0.0061 15.7 9.5 2.9 2 2 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx Neur_chan_LBD PF02931.18 EMC78094.1 - 3.9e-56 189.6 0.0 5.5e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC78094.1 - 3.4e-46 158.0 2.4 2.4e-36 125.8 2.5 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region NTF2 PF02136.15 EMC78095.1 - 7.1e-23 81.2 0.1 1.3e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EMC78095.1 - 6.5e-11 41.7 0.1 8.2e-10 38.1 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78095.1 - 5.8e-09 35.8 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78095.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3235 PF11574.3 EMC78095.1 - 0.38 11.0 2.3 0.55 10.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) HMA PF00403.21 EMC78096.1 - 8.3e-10 38.6 0.1 9.7e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain FRD2 PF03197.8 EMC78096.1 - 0.037 14.5 0.4 0.093 13.2 0.1 1.6 1 1 1 2 2 2 0 Bacteriophage FRD2 protein SPARC_Ca_bdg PF10591.4 EMC78097.1 - 2.1e-42 143.6 0.6 4.3e-42 142.7 0.4 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.16 EMC78097.1 - 3.3e-12 46.2 4.6 3.3e-12 46.2 3.2 2.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC78097.1 - 5.4e-11 42.2 2.1 5.4e-11 42.2 1.5 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 EMC78097.1 - 2.1e-10 40.2 10.5 2.1e-10 40.2 7.3 2.0 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.27 EMC78097.1 - 0.063 12.6 0.0 0.52 9.7 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EMC78097.1 - 0.086 12.7 0.1 0.51 10.3 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EMC78097.1 - 0.58 10.3 3.6 0.89 9.7 0.3 2.8 2 2 0 2 2 2 0 EF-hand domain pair Cadherin PF00028.12 EMC78098.1 - 0 1572.5 46.5 7.2e-23 80.6 0.0 33.7 34 0 0 34 34 34 33 Cadherin domain Laminin_G_2 PF02210.19 EMC78098.1 - 1.7e-15 57.2 0.3 6e-15 55.4 0.2 2.1 1 0 0 1 1 1 1 Laminin G domain Cadherin_2 PF08266.7 EMC78098.1 - 4.9e-15 54.8 0.0 0.84 9.2 0.0 14.6 20 0 0 20 20 20 2 Cadherin-like EGF PF00008.22 EMC78098.1 - 3.6e-11 42.7 31.9 1.7e-06 27.8 7.0 3.5 3 0 0 3 3 3 2 EGF-like domain Laminin_G_1 PF00054.18 EMC78098.1 - 6.7e-11 42.3 0.0 2.6e-10 40.4 0.0 2.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 EMC78098.1 - 0.0057 16.8 4.8 0.0089 16.2 0.2 3.6 4 0 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.8 EMC78098.1 - 5.3 7.2 35.7 2.7 8.2 3.2 3.8 3 0 0 3 3 3 0 EGF-like domain E1_DerP2_DerF2 PF02221.10 EMC78100.1 - 2.4e-27 95.8 0.1 2.9e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 ML domain MDMPI_N PF11716.3 EMC78101.1 - 0.033 14.6 1.7 0.068 13.6 1.2 1.5 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF3972 PF13118.1 EMC78101.1 - 0.073 13.1 5.6 0.095 12.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Matrilin_ccoil PF10393.4 EMC78101.1 - 0.093 12.1 1.4 0.18 11.1 1.0 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 EMC78101.1 - 0.16 11.8 1.7 0.24 11.2 1.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3810 PF12725.2 EMC78101.1 - 0.16 10.8 2.6 0.19 10.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF342 PF03961.8 EMC78101.1 - 0.18 10.1 9.5 0.2 10.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PilJ PF13675.1 EMC78101.1 - 0.26 11.6 7.9 0.46 10.8 5.3 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spectrin PF00435.16 EMC78101.1 - 0.31 11.3 14.5 0.79 10.0 10.0 1.9 1 1 0 1 1 1 0 Spectrin repeat Syntaxin-6_N PF09177.6 EMC78101.1 - 0.49 10.8 7.2 0.14 12.6 2.5 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal COG5 PF10392.4 EMC78101.1 - 0.52 10.2 9.6 1.1 9.2 6.6 1.7 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ARD PF03079.9 EMC78101.1 - 0.74 9.7 7.2 0.3 11.0 2.0 1.9 1 1 1 2 2 2 0 ARD/ARD' family RICH PF05062.7 EMC78101.1 - 0.75 9.9 6.0 1.2 9.2 4.1 1.6 1 1 0 1 1 1 0 RICH domain TBPIP PF07106.8 EMC78101.1 - 1.1 8.7 10.9 1.3 8.5 7.3 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1789 PF08748.6 EMC78101.1 - 1.4 9.0 4.6 0.74 9.9 1.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) DivIVA PF05103.8 EMC78101.1 - 2 8.4 15.5 0.19 11.7 1.1 2.1 1 1 1 2 2 2 0 DivIVA protein YjcZ PF13990.1 EMC78101.1 - 2.2 7.3 12.7 2.5 7.1 8.8 1.1 1 0 0 1 1 1 0 YjcZ-like protein FlxA PF14282.1 EMC78101.1 - 2.6 8.0 15.4 0.086 12.7 4.7 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF3584 PF12128.3 EMC78101.1 - 3.4 4.8 20.9 3.6 4.7 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF16 PF01519.11 EMC78101.1 - 6 7.1 8.6 12 6.1 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 FUSC PF04632.7 EMC78101.1 - 9.2 4.5 7.1 12 4.2 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Annexin PF00191.15 EMC78102.1 - 1.2e-185 601.7 34.1 4.3e-25 87.4 0.3 8.1 8 0 0 8 8 8 8 Annexin GSHPx PF00255.14 EMC78103.1 - 4.2e-22 77.5 0.1 5.9e-22 77.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Dynactin_p62 PF05502.8 EMC78104.1 - 1.1e-95 321.2 19.7 3e-66 224.1 0.5 2.3 1 1 1 2 2 2 2 Dynactin p62 family Elf1 PF05129.8 EMC78104.1 - 0.35 10.5 6.5 0.84 9.3 2.8 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RRM_6 PF14259.1 EMC78105.1 - 2e-11 43.6 0.0 3.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC78105.1 - 2.1e-11 43.2 0.1 3.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78105.1 - 5.8e-11 42.0 0.3 1.1e-10 41.1 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC78105.1 - 6.6e-05 22.6 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EMC78105.1 - 0.0035 16.9 1.4 0.0035 16.9 1.0 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EMC78105.1 - 0.0036 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif FYVE PF01363.16 EMC78105.1 - 0.0076 16.1 1.1 0.0076 16.1 0.8 1.8 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.1 EMC78105.1 - 0.036 14.0 0.8 0.036 14.0 0.5 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Calsarcin PF05556.6 EMC78106.1 - 1.2e-58 198.5 0.5 1.5e-58 198.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) HSNSD PF12062.3 EMC78108.1 - 1.2e-263 874.8 0.0 1.7e-263 874.3 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 EMC78108.1 - 3.3e-46 157.7 0.0 5.2e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC78108.1 - 0.0083 17.0 1.7 0.012 16.5 0.1 2.2 2 1 0 2 2 2 1 Sulfotransferase family Ribosomal_S11 PF00411.14 EMC78109.1 - 1.7e-34 118.2 0.2 2.9e-34 117.5 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S11 MHC2-interact PF09307.5 EMC78110.1 - 1.7e-40 137.3 1.7 3.4e-40 136.3 1.2 1.4 1 0 0 1 1 1 1 CLIP, MHC2 interacting MHCassoc_trimer PF08831.5 EMC78110.1 - 3.1e-36 123.0 8.4 5.3e-36 122.3 5.8 1.4 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain Thyroglobulin_1 PF00086.13 EMC78110.1 - 4.6e-14 51.5 5.9 8.2e-14 50.7 4.1 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Sulfatase PF00884.18 EMC78112.1 - 2.3e-70 237.2 0.1 3.1e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMC78112.1 - 0.0037 17.5 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Pkinase PF00069.20 EMC78113.1 - 1.6e-74 250.3 0.0 4.4e-74 248.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain CaMKII_AD PF08332.5 EMC78113.1 - 4.8e-64 213.9 0.0 8.5e-64 213.2 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Pkinase_Tyr PF07714.12 EMC78113.1 - 1.5e-32 112.7 0.0 2.3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4440 PF14534.1 EMC78113.1 - 1.2e-09 38.2 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EMC78113.1 - 2.2e-09 37.4 0.0 4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.18 EMC78113.1 - 0.0025 17.6 0.2 1.5 8.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC78113.1 - 0.023 13.7 0.1 0.046 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rsd_AlgQ PF04353.8 EMC78113.1 - 0.095 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ SNF PF00209.13 EMC78115.1 - 7.7e-223 740.6 35.9 1.1e-222 740.2 24.9 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caudal_act PF04731.7 EMC78116.1 - 1.2e-46 158.4 16.3 2.1e-46 157.6 11.3 1.4 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 EMC78116.1 - 1.9e-21 75.4 2.2 3.1e-21 74.7 1.5 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC78116.1 - 0.044 13.4 0.4 0.095 12.4 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain Pkinase_Tyr PF07714.12 EMC78117.1 - 9.3e-108 359.1 0.0 1.4e-107 358.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC78117.1 - 4.5e-48 163.6 0.0 5.5e-29 101.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 EMC78117.1 - 1.3e-27 95.4 3.7 1.7e-10 40.5 0.1 4.8 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78117.1 - 5.6e-22 77.6 9.8 1.9e-11 43.9 0.1 5.8 5 2 0 5 5 5 4 Immunoglobulin domain ig PF00047.20 EMC78117.1 - 6.4e-17 61.4 5.8 8.2e-07 29.0 0.0 6.1 5 0 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 EMC78117.1 - 1.4e-13 51.0 15.3 7.5e-05 23.1 0.3 5.8 6 1 0 6 6 6 4 Immunoglobulin domain V-set PF07686.12 EMC78117.1 - 2.9e-09 36.8 3.1 6.6e-06 25.9 0.1 4.4 4 1 0 4 4 4 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC78117.1 - 4.3e-05 23.3 7.8 0.19 11.6 0.0 4.5 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Herpes_gI PF01688.12 EMC78117.1 - 0.025 13.6 0.0 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein I Pkinase_Tyr PF07714.12 EMC78118.1 - 1.6e-106 355.1 0.0 2.3e-106 354.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC78118.1 - 1.5e-44 152.1 0.0 8.7e-27 93.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 EMC78118.1 - 8.3e-24 83.2 0.1 0.00035 20.3 0.0 6.0 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78118.1 - 8.6e-22 77.0 3.0 7.4e-07 29.2 0.0 5.0 4 1 1 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 EMC78118.1 - 9.7e-19 67.6 8.2 2.9e-05 24.4 0.4 5.1 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.20 EMC78118.1 - 5.8e-11 42.3 7.2 0.00075 19.5 0.1 4.4 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 EMC78118.1 - 8.6e-08 32.0 13.2 0.0051 16.6 1.1 6.4 5 2 0 5 5 5 3 Immunoglobulin V-set domain APH PF01636.18 EMC78118.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family C2-set PF05790.10 EMC78118.1 - 0.013 15.4 1.9 5.5 7.0 0.0 3.6 5 0 0 5 5 5 0 Immunoglobulin C2-set domain HMG_box_2 PF09011.5 EMC78119.1 - 2.5e-11 43.7 0.4 5.6e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EMC78119.1 - 4.1e-11 42.9 0.4 9.8e-11 41.7 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box 7tm_1 PF00001.16 EMC78121.1 - 1.7e-57 194.4 21.2 2.1e-57 194.2 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78121.1 - 1.3e-11 44.1 19.2 1.8e-11 43.6 13.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC78121.1 - 0.00028 20.1 13.3 0.00028 20.1 9.2 2.3 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-C3HC4 PF00097.20 EMC78122.1 - 2.4e-08 33.5 7.5 2.8e-08 33.3 5.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC78122.1 - 2.9e-08 33.4 6.8 3.4e-08 33.2 4.7 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMC78122.1 - 4.7e-08 32.9 8.3 5.4e-08 32.7 5.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMC78122.1 - 8.1e-06 25.5 2.6 8.5e-06 25.4 1.8 1.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EMC78122.1 - 1.8e-05 24.4 8.5 2e-05 24.3 5.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC78122.1 - 3e-05 23.6 6.6 3.2e-05 23.5 4.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC78122.1 - 3.5e-05 23.4 3.9 4.5e-05 23.0 2.7 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC78122.1 - 0.00018 21.1 7.8 0.00021 20.9 5.4 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EMC78122.1 - 0.0019 17.6 1.2 0.0024 17.3 0.9 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SPRY PF00622.23 EMC78123.1 - 5.2e-22 78.2 0.1 6.5e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 EMC78123.1 - 2.2e-08 33.4 0.3 4.1e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 SPRY-associated domain Pkinase_Tyr PF07714.12 EMC78124.1 - 5e-105 350.2 0.0 8.2e-105 349.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC78124.1 - 9.4e-46 156.0 0.0 3.9e-32 111.4 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Ig_2 PF13895.1 EMC78124.1 - 5.7e-44 148.1 11.4 1.8e-08 34.4 0.0 7.4 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.11 EMC78124.1 - 2.1e-43 146.1 10.9 1.2e-14 53.8 0.0 7.7 6 1 2 8 8 8 4 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC78124.1 - 3.3e-32 110.7 6.1 1.9e-07 31.4 0.0 8.2 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 EMC78124.1 - 3.1e-21 75.4 8.8 6.9e-05 22.7 0.1 6.9 5 2 0 5 5 5 4 Immunoglobulin V-set domain ig PF00047.20 EMC78124.1 - 2.8e-19 68.9 14.6 8.5e-05 22.6 0.2 7.5 6 2 0 6 6 6 4 Immunoglobulin domain C1-set PF07654.10 EMC78124.1 - 1.6e-06 28.0 1.7 0.015 15.2 0.0 5.2 5 0 0 5 5 5 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC78124.1 - 1.5e-05 24.8 6.9 0.2 11.5 0.0 4.7 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC78124.1 - 0.0002 19.7 0.1 0.29 9.3 0.0 3.6 2 1 0 3 3 3 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 EMC78124.1 - 0.00037 20.3 1.5 0.22 11.4 0.0 3.7 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 zf-RING_2 PF13639.1 EMC78126.1 - 5e-13 48.6 11.7 8.5e-13 47.9 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EMC78126.1 - 3.4e-11 42.7 0.0 6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EMC78126.1 - 4.9e-08 32.9 6.1 9.6e-08 32.0 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC78126.1 - 1.8e-07 30.6 10.9 3.1e-07 29.9 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC78126.1 - 2.1e-07 30.5 10.2 3.4e-07 29.8 7.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC78126.1 - 4.6e-06 26.1 8.3 7.5e-06 25.5 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC78126.1 - 7.5e-06 25.8 11.5 1.3e-05 25.0 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC78126.1 - 0.012 15.4 5.4 0.025 14.4 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CoA_binding_3 PF13727.1 EMC78126.1 - 0.066 13.0 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 CoA-binding domain DUF2254 PF10011.4 EMC78126.1 - 0.11 10.9 0.9 0.12 10.7 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) zf-RING_UBOX PF13445.1 EMC78126.1 - 0.21 11.3 6.2 0.51 10.1 4.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger UPF0233 PF06781.7 EMC78126.1 - 0.21 11.2 1.8 2.7 7.7 0.6 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) Prok-RING_1 PF14446.1 EMC78126.1 - 1.2 8.9 10.9 0.16 11.7 2.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EMC78126.1 - 2.7 7.7 10.5 4.6 7.0 7.3 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EMC78126.1 - 4 7.5 9.5 9.3 6.3 6.6 1.6 1 0 0 1 1 1 0 RING-variant domain RabGAP-TBC PF00566.13 EMC78127.1 - 2.3e-48 164.5 0.1 2.3e-48 164.5 0.1 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.15 EMC78127.1 - 1.4e-36 123.8 0.1 2.3e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.27 EMC78127.1 - 0.0016 17.5 1.2 0.0031 16.7 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMC78127.1 - 0.008 16.3 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC78127.1 - 0.027 14.3 0.1 0.12 12.3 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 EMC78127.1 - 0.052 13.1 0.1 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair BTV_NS2 PF04514.7 EMC78128.1 - 0.013 14.4 3.0 0.018 13.9 2.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 ZZ PF00569.12 EMC78129.1 - 6.2e-12 44.8 4.3 1e-11 44.1 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.19 EMC78129.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 PB1 domain MAPEG PF01124.13 EMC78130.1 - 0.0029 17.2 12.7 0.018 14.6 0.0 2.7 2 1 1 3 3 3 2 MAPEG family Calreticulin PF00262.13 EMC78132.1 - 1.6e-162 540.3 16.7 1.6e-162 540.3 11.6 1.6 2 0 0 2 2 2 1 Calreticulin family DUF1510 PF07423.6 EMC78132.1 - 0.00034 20.0 8.4 0.00095 18.5 5.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 EMC78132.1 - 0.0072 15.3 2.4 0.0072 15.3 1.7 3.4 2 1 1 3 3 3 1 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 EMC78132.1 - 0.014 13.1 3.4 0.018 12.8 2.4 1.1 1 0 0 1 1 1 0 Ycf1 MAPEG PF01124.13 EMC78133.1 - 5.7e-17 61.5 5.4 7.2e-17 61.2 3.4 1.4 1 1 0 1 1 1 1 MAPEG family dNK PF01712.14 EMC78134.1 - 3.5e-43 146.9 2.5 5.1e-43 146.4 1.8 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 EMC78134.1 - 1.1e-06 28.9 0.1 4e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EMC78134.1 - 0.00033 20.5 0.0 0.0019 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMC78134.1 - 0.01 15.1 0.1 0.051 12.9 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.1 EMC78134.1 - 0.074 13.0 0.1 0.19 11.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain RUN PF02759.14 EMC78135.1 - 4.1e-30 104.2 0.0 4.1e-30 104.2 0.0 2.6 3 1 0 3 3 3 1 RUN domain FYVE PF01363.16 EMC78135.1 - 4.6e-20 71.2 10.3 4.6e-20 71.2 7.2 2.4 2 0 0 2 2 2 1 FYVE zinc finger DUF972 PF06156.8 EMC78135.1 - 0.0026 18.0 7.4 0.0026 18.0 5.2 5.3 1 1 3 5 5 5 2 Protein of unknown function (DUF972) zf-RING_5 PF14634.1 EMC78135.1 - 0.025 14.2 14.9 0.069 12.8 10.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Reo_sigmaC PF04582.7 EMC78135.1 - 0.036 13.2 10.6 0.24 10.5 3.0 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ADK_lid PF05191.9 EMC78135.1 - 0.19 11.4 3.8 0.73 9.5 2.6 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid Pep_M12B_propep PF01562.14 EMC78136.1 - 2.9e-27 95.0 0.0 5e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.9 EMC78136.1 - 2.5e-25 88.5 0.0 4.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 EMC78136.1 - 3.1e-22 78.4 62.1 1.2e-09 38.1 4.5 5.8 6 0 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.14 EMC78136.1 - 6.4e-20 71.6 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 EMC78136.1 - 3.7e-14 53.1 0.1 7.7e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC78136.1 - 1.2e-11 45.2 0.1 2.3e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC78136.1 - 1.2e-10 41.6 0.3 2.4e-10 40.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC78136.1 - 1.1e-08 34.9 0.1 2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC78136.1 - 0.0003 20.5 0.1 0.00075 19.2 0.1 1.7 1 0 0 1 1 1 1 Matrixin PLAC PF08686.6 EMC78136.1 - 0.0036 17.5 7.4 0.0036 17.5 5.1 3.4 3 0 0 3 3 3 1 PLAC (protease and lacunin) domain Peptidase_M7 PF02031.11 EMC78136.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DEPP PF15343.1 EMC78137.1 - 0.0073 15.9 0.2 0.022 14.3 0.0 1.9 2 0 0 2 2 2 1 Decidual protein induced by progesterone family Exo_endo_phos PF03372.18 EMC78138.1 - 5.9e-22 78.8 0.0 7.8e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EMC78138.1 - 2.6e-16 58.8 16.1 2.8e-10 39.5 1.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC78138.1 - 1.4e-13 50.3 21.7 1.7e-10 40.4 5.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMC78138.1 - 1.9e-06 27.1 22.3 0.021 14.8 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC78138.1 - 8.8e-06 25.1 13.2 0.46 10.8 0.1 5.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EMC78138.1 - 0.0026 17.6 9.9 1.3 9.3 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich repeat DUF713 PF05218.9 EMC78138.1 - 0.065 12.9 0.7 0.15 11.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF713) SIS PF01380.17 EMC78139.1 - 1.2e-63 212.5 0.0 1.4e-34 118.4 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EMC78139.1 - 5.2e-28 97.7 0.0 3.4e-21 75.3 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMC78139.1 - 3.1e-17 62.7 0.0 6.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMC78139.1 - 8.8e-15 54.5 0.0 2.7e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EMC78139.1 - 3.5e-08 32.4 0.0 5.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EMC78139.1 - 0.003 17.2 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 SIS domain Acetyltransf_6 PF13480.1 EMC78139.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EMC78140.1 - 1.3e-66 224.4 0.0 1.6e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78140.1 - 1.5e-29 102.8 0.1 2.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC78140.1 - 3.4e-06 26.2 0.2 5.6e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC78140.1 - 0.00034 20.4 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC78140.1 - 0.00035 19.9 0.2 0.00061 19.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EMC78140.1 - 0.00087 18.3 0.1 0.0037 16.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF1651 PF07864.6 EMC78140.1 - 0.055 13.5 0.2 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) Tropomyosin_1 PF12718.2 EMC78141.1 - 0.0081 16.0 10.7 0.0081 16.0 7.4 1.4 2 0 0 2 2 2 1 Tropomyosin like Laminin_II PF06009.7 EMC78141.1 - 0.041 13.6 0.3 0.068 12.9 0.2 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF4574 PF15141.1 EMC78141.1 - 0.053 13.2 0.7 0.053 13.2 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) Jnk-SapK_ap_N PF09744.4 EMC78141.1 - 0.14 12.1 7.1 0.28 11.1 4.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-Q PF13094.1 EMC78141.1 - 0.3 11.0 11.0 0.57 10.1 7.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF342 PF03961.8 EMC78141.1 - 0.44 8.9 2.2 0.44 8.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3435 PF11917.3 EMC78141.1 - 0.47 9.1 10.0 0.62 8.7 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DMPK_coil PF08826.5 EMC78141.1 - 0.58 10.1 15.8 1.4 8.8 1.8 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like DASH_Spc34 PF08657.5 EMC78141.1 - 0.76 9.3 7.0 1.2 8.7 4.9 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 OEP PF02321.13 EMC78141.1 - 1.2 8.6 12.5 1.7 8.2 8.7 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein Borrelia_P83 PF05262.6 EMC78141.1 - 1.5 7.0 7.8 3.4 5.8 4.6 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein Ax_dynein_light PF10211.4 EMC78141.1 - 2.9 7.6 12.7 8.2 6.2 8.8 1.7 1 1 0 1 1 1 0 Axonemal dynein light chain Kinetocho_Slk19 PF12709.2 EMC78141.1 - 4.7 7.3 9.9 0.67 10.0 1.9 2.2 1 1 1 2 2 2 0 Central kinetochore-associated DivIC PF04977.10 EMC78141.1 - 4.8 6.7 10.7 1 8.8 3.3 2.3 1 1 1 2 2 2 0 Septum formation initiator IncA PF04156.9 EMC78141.1 - 4.9 6.7 14.3 7.4 6.1 9.9 1.5 1 1 0 1 1 1 0 IncA protein DUF4200 PF13863.1 EMC78141.1 - 6.6 6.6 17.2 15 5.5 12.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) RasGEF PF00617.14 EMC78142.1 - 3.2e-50 170.4 0.1 6e-50 169.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC78142.1 - 6e-07 29.5 0.1 2.2e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF948 PF06103.6 EMC78142.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 EMC78143.1 - 1.5e-66 224.2 0.8 2.4e-66 223.5 0.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78143.1 - 4.6e-26 91.4 1.5 1.4e-25 89.9 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Aminotran_3 PF00202.16 EMC78144.1 - 4e-78 262.6 0.0 4.7e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMC78144.1 - 0.0013 17.7 0.1 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3301 PF11743.3 EMC78144.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) RRM_1 PF00076.17 EMC78145.1 - 2.3e-40 136.0 0.7 3.7e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78145.1 - 7.4e-31 105.9 0.1 2.8e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78145.1 - 2.1e-08 33.8 0.1 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC78145.1 - 2.4e-06 27.3 0.1 0.082 12.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EMC78145.1 - 7.1e-06 25.7 0.0 0.00045 19.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 EMC78145.1 - 0.00056 19.8 0.6 0.15 12.1 0.1 2.6 2 1 0 3 3 3 2 Nmi/IFP 35 domain (NID) NDK PF00334.14 EMC78146.1 - 2e-36 124.7 0.0 2.4e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.8 EMC78146.1 - 1.8e-17 62.4 0.4 2.8e-17 61.8 0.3 1.3 1 0 0 1 1 1 1 Dpy-30 motif wnt PF00110.14 EMC78147.1 - 1.3e-98 329.9 25.6 1.6e-98 329.6 17.7 1.0 1 0 0 1 1 1 1 wnt family Thymosin PF01290.15 EMC78148.1 - 3.4e-21 74.5 10.7 3.7e-21 74.4 7.4 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.15 EMC78148.1 - 0.0014 18.1 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 WH2 motif PKD_channel PF08016.7 EMC78149.1 - 1.4e-135 452.0 22.2 1.8e-135 451.6 15.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EMC78149.1 - 3.6e-23 81.8 31.3 3.6e-23 81.8 21.7 1.9 2 0 0 2 2 2 1 Ion transport protein Abhydrolase_9_N PF15420.1 EMC78149.1 - 7.6 6.2 8.2 1.5 8.4 0.8 2.8 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus I-set PF07679.11 EMC78150.1 - 1.1e-18 66.8 0.0 1.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78150.1 - 1.4e-07 31.5 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC78150.1 - 1e-05 25.9 0.0 0.00021 21.7 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC78150.1 - 6.6e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC78150.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain 7tm_1 PF00001.16 EMC78151.1 - 7.5e-57 192.3 23.1 9.5e-57 192.0 16.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78151.1 - 5.3e-06 25.7 22.8 2.4e-05 23.6 15.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC78151.1 - 0.0029 16.7 35.1 0.13 11.3 24.3 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SecD_SecF PF02355.11 EMC78151.1 - 5.6 6.1 11.3 1.7 7.7 4.7 2.3 3 0 0 3 3 3 0 Protein export membrane protein Kelch_1 PF01344.20 EMC78152.1 - 2.3e-76 251.1 11.7 2.8e-15 55.5 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC78152.1 - 1.5e-41 138.9 3.5 1.1e-07 31.6 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.10 EMC78152.1 - 5.2e-37 125.8 0.7 1.4e-36 124.4 0.5 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 EMC78152.1 - 3.2e-32 110.8 0.9 6.6e-32 109.7 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 EMC78152.1 - 3.8e-30 103.3 11.2 2.2e-06 27.6 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC78152.1 - 4e-28 96.0 6.4 6.4e-05 22.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EMC78152.1 - 8.4e-27 92.7 4.8 2.4e-05 24.0 0.0 6.2 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC78152.1 - 3.5e-08 33.2 13.1 0.42 10.6 0.2 5.4 5 0 0 5 5 5 4 Kelch motif Ashwin PF15323.1 EMC78152.1 - 0.016 15.1 0.6 0.031 14.2 0.4 1.4 1 0 0 1 1 1 0 Developmental protein Skp1_POZ PF03931.10 EMC78152.1 - 0.021 14.9 0.2 0.066 13.3 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain PQQ_3 PF13570.1 EMC78152.1 - 1.9 8.8 12.0 24 5.3 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain SPARC_Ca_bdg PF10591.4 EMC78153.1 - 9e-31 106.2 0.4 1.9e-30 105.1 0.3 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.13 EMC78153.1 - 1.1e-16 59.8 5.7 1.1e-16 59.8 3.9 2.6 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.10 EMC78153.1 - 3.3e-10 39.7 5.6 9.1e-10 38.3 3.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC78153.1 - 1.1e-08 34.9 5.2 5.7e-08 32.6 3.6 2.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain NOSIC PF08060.8 EMC78153.1 - 0.15 11.8 0.1 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 NOSIC (NUC001) domain MH2 PF03166.9 EMC78154.1 - 8.1e-79 263.6 0.2 1.1e-78 263.2 0.2 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 EMC78154.1 - 3e-42 142.8 0.3 6.8e-42 141.6 0.2 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 EMC78154.1 - 2.7e-07 30.3 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Fasciclin PF02469.17 EMC78155.1 - 7.1e-101 333.1 6.2 1.7e-32 112.0 0.1 4.9 4 1 0 4 4 4 4 Fasciclin domain Peptidase_M23 PF01551.17 EMC78156.1 - 1.3e-07 31.5 0.0 1.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M23 Peptidase_M23 PF01551.17 EMC78157.1 - 4.6e-12 45.8 0.0 1.2e-05 25.2 0.0 2.7 2 1 0 2 2 2 2 Peptidase family M23 zf-A20 PF01754.11 EMC78157.1 - 0.082 12.5 7.5 0.65 9.6 0.9 2.8 2 0 0 2 2 2 0 A20-like zinc finger F-box-like PF12937.2 EMC78158.1 - 2.1e-11 43.3 3.0 2.3e-11 43.2 0.9 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMC78158.1 - 1.8e-10 40.1 1.2 1.8e-10 40.1 0.9 2.3 2 0 0 2 2 2 1 F-box domain DUF4354 PF14263.1 EMC78158.1 - 0.019 14.6 0.2 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) Humanin PF15040.1 EMC78159.1 - 5.2 6.4 8.6 0.098 11.9 1.0 1.9 2 1 0 2 2 2 0 Humanin family Mito_carr PF00153.22 EMC78160.1 - 6.4e-64 211.7 3.2 1.5e-22 79.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF787 PF05619.6 EMC78160.1 - 0.0035 16.0 0.0 0.0057 15.3 0.0 1.3 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF787) Jiraiya PF15038.1 EMC78160.1 - 0.15 11.4 0.4 0.43 9.9 0.1 1.8 2 0 0 2 2 2 0 Jiraiya IL8 PF00048.15 EMC78162.1 - 1.9e-08 34.1 1.2 2.7e-08 33.6 0.8 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like KASH PF10541.4 EMC78162.1 - 0.2 11.5 1.2 0.35 10.7 0.8 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain Macro PF01661.16 EMC78163.1 - 8e-27 93.4 0.0 1.5e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Macro domain Histone PF00125.19 EMC78163.1 - 1.4e-22 79.5 0.1 4e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC78163.1 - 0.0063 16.5 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.15 EMC78163.1 - 0.025 14.4 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Clp amino terminal domain YihI PF04220.7 EMC78163.1 - 0.11 11.7 5.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) Pterin_4a PF01329.14 EMC78164.1 - 9.4e-32 108.6 0.2 1e-31 108.5 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 EMC78164.1 - 0.011 15.5 0.0 0.048 13.5 0.0 1.8 1 1 1 2 2 2 0 Translation-initiation factor 2 Ion_trans PF00520.26 EMC78164.1 - 0.15 11.3 0.1 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein Thioredoxin PF00085.15 EMC78165.1 - 2.7e-10 39.8 0.0 3.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EMC78165.1 - 0.047 12.4 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosducin Peptidase_M57 PF12388.3 EMC78166.1 - 0.65 9.2 2.7 5.8 6.1 0.7 2.6 1 1 1 3 3 3 0 Dual-action HEIGH metallo-peptidase CAML PF14963.1 EMC78167.1 - 3.4e-125 416.7 0.0 3.9e-125 416.5 0.0 1.0 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand Sec23_trunk PF04811.10 EMC78168.1 - 1.1e-86 290.1 0.1 2e-86 289.3 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC78168.1 - 1e-24 85.9 0.7 2.1e-24 84.9 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMC78168.1 - 9.9e-21 74.0 0.0 2.6e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMC78168.1 - 1.1e-15 56.9 4.6 1.1e-15 56.9 3.2 2.0 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMC78168.1 - 1e-10 41.1 0.0 2.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.5 EMC78168.1 - 0.027 14.7 0.0 0.082 13.1 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein Arf PF00025.16 EMC78169.1 - 5.6e-63 211.3 0.0 6.5e-63 211.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC78169.1 - 8.2e-10 37.9 0.1 2.9e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMC78169.1 - 1.6e-09 37.2 0.0 2.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC78169.1 - 7.1e-07 29.7 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMC78169.1 - 8.3e-07 28.5 0.0 9.2e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EMC78169.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC78169.1 - 0.00022 20.6 0.0 0.0028 17.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC78169.1 - 0.0012 18.0 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EMC78169.1 - 0.091 12.2 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-HC5HC2H_2 PF13832.1 EMC78170.1 - 2.5e-30 104.7 8.0 2.5e-30 104.7 5.5 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC78170.1 - 6.6e-23 80.6 8.0 6.6e-23 80.6 5.5 3.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 EMC78170.1 - 5.2e-16 59.2 1.1 5.2e-16 59.2 0.7 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EMC78170.1 - 1e-12 47.1 6.7 1e-12 47.1 4.6 3.8 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 EMC78170.1 - 1.8e-09 37.1 8.1 1.8e-09 37.1 5.6 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EMC78170.1 - 0.0041 16.8 4.3 0.0041 16.8 3.0 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UQ_con PF00179.21 EMC78172.1 - 1.5e-46 157.2 0.1 3.2e-46 156.2 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC78172.1 - 1.9e-05 24.3 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC78172.1 - 0.0021 17.9 0.1 0.0028 17.5 0.0 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EMC78172.1 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Metallophos PF00149.23 EMC78173.1 - 2.1e-41 141.5 0.7 2.7e-41 141.1 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1 PF01466.14 EMC78175.1 - 9.2e-41 137.7 0.8 1.6e-40 137.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EMC78175.1 - 3.2e-29 100.7 0.6 8.5e-29 99.4 0.1 1.9 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain CTNNB1_binding PF08347.6 EMC78176.1 - 3.3e-37 128.7 7.5 3.3e-37 128.7 5.2 2.3 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.14 EMC78176.1 - 3e-22 78.6 1.0 5.6e-22 77.7 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC78176.1 - 3e-08 33.9 1.1 7.3e-08 32.6 0.7 1.6 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EMC78176.1 - 0.0055 16.0 0.3 0.0088 15.3 0.2 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Porin_3 PF01459.17 EMC78177.1 - 2.1e-76 256.8 3.4 2.4e-76 256.6 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4534 PF15049.1 EMC78178.1 - 0.056 13.0 0.3 0.086 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Borrelia_REV PF03978.8 EMC78178.1 - 0.064 12.9 0.4 0.064 12.9 0.3 2.1 2 1 1 3 3 3 0 Borrelia burgdorferi REV protein I-set PF07679.11 EMC78179.1 - 9e-26 89.5 0.0 1.1e-15 57.2 0.0 3.6 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78179.1 - 4.1e-20 71.6 0.0 1e-09 38.3 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 EMC78179.1 - 2.2e-18 66.4 0.4 8.9e-12 45.3 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 EMC78179.1 - 3.9e-12 46.1 0.2 2.1e-05 24.5 0.0 3.7 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 EMC78179.1 - 8.1e-10 38.6 0.3 1.7e-05 24.7 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin V-set domain EF-hand_7 PF13499.1 EMC78179.1 - 1.6e-08 34.5 4.5 3.7e-08 33.3 3.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair Kazal_2 PF07648.10 EMC78179.1 - 4.2e-08 32.9 2.9 1.2e-07 31.5 2.0 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_5 PF13202.1 EMC78179.1 - 6.8e-08 31.5 0.1 0.0033 16.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 EMC78179.1 - 1.1e-07 30.5 0.0 0.00024 20.1 0.0 2.8 2 0 0 2 2 2 2 EF hand Kazal_1 PF00050.16 EMC78179.1 - 1.3e-07 31.4 7.9 3.6e-07 30.0 5.5 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.1 EMC78179.1 - 1.9e-06 27.2 1.0 0.011 15.5 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EMC78179.1 - 0.00037 20.5 0.2 0.0007 19.6 0.2 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 EMC78179.1 - 0.0014 18.2 0.2 0.075 12.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair C2-set_2 PF08205.7 EMC78179.1 - 0.0057 16.5 0.0 0.42 10.5 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain LVIVD PF08309.6 EMC78179.1 - 0.075 12.0 0.2 0.29 10.1 0.0 2.1 2 0 0 2 2 2 0 LVIVD repeat RasGEF PF00617.14 EMC78181.1 - 1.4e-66 223.8 0.3 2.4e-66 223.0 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC78181.1 - 1.2e-18 67.1 0.4 3.7e-18 65.5 0.3 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif cNMP_binding PF00027.24 EMC78181.1 - 2.2e-13 49.7 0.0 2.2e-09 37.0 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RA PF00788.18 EMC78181.1 - 6.9e-13 48.8 0.0 1.8e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 EMC78181.1 - 2e-11 43.9 0.0 6.2e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC78181.1 - 0.00019 21.2 0.0 0.00088 19.1 0.0 2.1 1 0 0 1 1 1 1 PDZ domain DUF1944 PF09175.5 EMC78181.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) FNIP_M PF14637.1 EMC78182.1 - 2.3e-86 289.1 0.0 4.4e-86 288.2 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 EMC78182.1 - 9.6e-71 237.1 0.1 2.6e-70 235.6 0.1 1.8 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 EMC78182.1 - 2.6e-36 124.9 0.4 2.6e-36 124.9 0.3 2.6 3 0 0 3 3 3 1 Folliculin-interacting protein N-terminus AMP-binding PF00501.23 EMC78184.1 - 4.3e-100 335.0 0.0 6.7e-100 334.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme P4Ha_N PF08336.6 EMC78185.1 - 2.6e-43 147.0 0.2 2.6e-43 147.0 0.2 2.0 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 EMC78185.1 - 4.5e-12 46.1 0.0 9.5e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMC78185.1 - 1.9e-07 31.5 0.1 5.9e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PDZ PF00595.19 EMC78186.1 - 7.7e-18 64.4 0.0 1.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 EMC78186.1 - 2.4e-14 53.1 4.4 4.2e-14 52.3 3.1 1.4 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 EMC78186.1 - 2.9e-06 27.0 0.0 5.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain BNR_2 PF13088.1 EMC78186.1 - 0.006 15.9 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain zf-SNAP50_C PF12251.3 EMC78186.1 - 0.65 9.3 2.9 5.9 6.2 0.8 2.3 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Sugar_tr PF00083.19 EMC78187.1 - 7.4e-28 97.3 25.6 9.3e-28 96.9 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC78187.1 - 6.7e-24 84.2 58.0 2.1e-21 76.0 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC78187.1 - 0.00011 20.6 3.7 0.00011 20.6 2.5 3.6 2 1 1 3 3 3 2 MFS/sugar transport protein Kazal_1 PF00050.16 EMC78188.1 - 1.8e-15 56.6 1.5 1.8e-15 56.6 1.0 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC78188.1 - 2.6e-12 46.4 2.6 2.9e-12 46.3 1.8 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain IL12p40_C PF10420.4 EMC78189.1 - 8.1e-26 89.9 2.1 6e-25 87.1 1.1 2.5 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus Ig_3 PF13927.1 EMC78189.1 - 0.00026 21.4 2.3 0.031 14.7 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.1 EMC78189.1 - 0.0003 20.8 0.9 0.0022 18.0 0.0 2.6 1 1 2 3 3 3 1 Immunoglobulin domain 7tm_1 PF00001.16 EMC78190.1 - 8e-84 280.7 8.2 1.1e-83 280.3 5.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78190.1 - 6.1e-16 58.3 4.5 1.4e-15 57.1 3.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC78190.1 - 0.00021 20.5 8.2 0.00063 18.9 5.7 1.8 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TPR_1 PF00515.23 EMC78191.1 - 1.5e-24 84.5 3.2 5.9e-07 28.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMC78191.1 - 1.5e-23 82.1 5.0 1.6e-17 62.8 0.4 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC78191.1 - 6.3e-18 63.1 3.4 3.5e-05 23.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC78191.1 - 7.2e-10 37.9 4.7 0.0012 18.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC78191.1 - 2.1e-09 37.1 1.9 0.00012 21.9 0.7 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC78191.1 - 1e-08 35.5 1.2 4.4e-06 27.2 1.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78191.1 - 3.3e-07 30.3 1.7 0.0041 17.6 0.3 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMC78191.1 - 7e-07 28.5 2.7 0.0041 16.2 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC78191.1 - 2.7e-06 27.1 3.1 6.9e-06 25.8 1.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC78191.1 - 4e-06 27.0 6.3 0.00011 22.4 1.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC78191.1 - 9.6e-06 25.0 1.3 0.039 13.7 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC78191.1 - 4.5e-05 23.3 4.6 0.0015 18.5 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC78191.1 - 0.0003 21.0 3.1 0.008 16.5 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EMC78191.1 - 0.015 14.7 1.6 0.015 14.7 1.1 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF3856 PF12968.2 EMC78191.1 - 0.027 14.3 0.8 7.3 6.4 0.0 3.1 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 EMC78191.1 - 0.031 14.1 2.1 1.3 8.9 0.1 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PaaX_C PF08223.6 EMC78191.1 - 0.04 13.6 1.0 0.064 12.9 0.7 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain A2M_N PF01835.14 EMC78191.1 - 0.079 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 MG2 domain NYD-SP12_N PF15015.1 EMC78191.1 - 0.19 9.9 0.0 0.19 9.9 0.0 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal PWWP PF00855.12 EMC78192.1 - 1.7e-12 47.3 0.1 1.7e-12 47.3 0.0 2.8 2 1 0 2 2 2 1 PWWP domain DUF1018 PF06252.7 EMC78192.1 - 0.88 10.0 10.3 4.4 7.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1018) Lipocalin_7 PF14651.1 EMC78193.1 - 8.4e-60 200.1 1.1 9.3e-60 199.9 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 EMC78193.1 - 3.8e-09 36.6 0.9 4e-09 36.5 0.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4166 PF13761.1 EMC78193.1 - 0.0067 16.3 0.0 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4166) Cyclin_C PF02984.14 EMC78194.1 - 2.5e-24 85.4 5.3 9.3e-24 83.6 1.2 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 EMC78194.1 - 1.5e-20 73.0 7.1 3e-20 72.0 1.1 2.7 1 1 2 3 3 3 1 Cyclin, N-terminal domain Methuselah_N PF06652.7 EMC78194.1 - 0.0066 16.0 1.4 0.013 15.0 1.0 1.5 1 0 0 1 1 1 1 Methuselah N-terminus C1q PF00386.16 EMC78195.1 - 4.6e-38 130.0 0.0 5.6e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC78195.1 - 1.3e-17 63.0 59.0 2.8e-09 36.3 24.4 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Securin PF04856.8 EMC78196.1 - 6.9e-11 42.3 0.4 1.3e-10 41.4 0.3 1.4 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor E1-E2_ATPase PF00122.15 EMC78197.1 - 1.2e-14 53.8 0.0 3.6e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMC78197.1 - 6.6e-14 52.8 0.0 2.2e-09 38.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC78197.1 - 7.6e-14 52.3 0.6 1.4e-12 48.1 0.4 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC78197.1 - 1.6e-08 34.3 0.0 8e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC78197.1 - 0.0078 15.8 3.2 0.009 15.6 0.2 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Neur_chan_LBD PF02931.18 EMC78198.1 - 1.6e-52 177.7 0.0 2.2e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC78198.1 - 2e-48 165.3 6.0 2.4e-42 145.4 2.7 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Cyclin_N PF00134.18 EMC78198.1 - 0.01 15.3 0.3 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Mito_fiss_reg PF05308.6 EMC78198.1 - 0.084 12.2 4.4 0.13 11.6 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4396 PF14342.1 EMC78198.1 - 0.79 9.8 8.6 4.7 7.3 6.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4396) Neur_chan_LBD PF02931.18 EMC78199.1 - 1.4e-52 177.9 0.0 1.9e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC78199.1 - 4.9e-45 154.2 5.8 1.3e-36 126.7 3.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC78200.1 - 4.8e-54 182.7 0.5 7.1e-54 182.2 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC78200.1 - 3.9e-50 170.9 3.7 8.9e-45 153.4 0.3 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Cyclin_N PF00134.18 EMC78201.1 - 1.6e-21 76.2 0.2 3.3e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Reo_sigmaC PF04582.7 EMC78202.1 - 7.5 5.6 42.0 2.5 7.2 1.0 5.1 1 1 3 5 5 5 0 Reovirus sigma C capsid protein RmlD_sub_bind PF04321.12 EMC78203.1 - 6.8e-81 271.2 0.0 8.1e-81 271.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EMC78203.1 - 7.8e-24 84.3 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMC78203.1 - 1.2e-09 37.4 0.1 9.6e-07 27.9 0.0 2.7 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EMC78203.1 - 4.1e-08 32.4 0.0 2.2e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EMC78203.1 - 2.8e-06 27.4 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMC78203.1 - 8.5e-05 21.3 0.1 0.00044 19.0 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMC78203.1 - 0.0058 16.5 0.4 0.073 12.9 0.0 2.6 2 2 1 3 3 3 1 short chain dehydrogenase Ten_N PF06484.7 EMC78204.1 - 1.2e-22 80.5 1.2 1.4e-22 80.3 0.8 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region YicC_N PF03755.8 EMC78204.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 YicC-like family, N-terminal region Ten_N PF06484.7 EMC78205.1 - 2.5e-85 286.8 29.4 4.1e-85 286.1 20.4 1.4 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.1 EMC78205.1 - 8.6e-31 105.4 0.5 1.7e-30 104.4 0.4 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin NHL PF01436.16 EMC78205.1 - 1.3e-12 46.9 2.4 0.0023 17.7 0.0 6.6 7 0 0 7 7 7 3 NHL repeat EGF_2 PF07974.8 EMC78205.1 - 5.7e-12 45.5 172.5 0.0015 18.6 9.7 10.0 10 0 0 10 10 10 8 EGF-like domain RHS_repeat PF05593.9 EMC78205.1 - 3.8e-11 42.8 35.6 0.00051 20.1 1.4 10.0 9 3 1 10 10 10 3 RHS Repeat CarboxypepD_reg PF13620.1 EMC78205.1 - 3.8e-05 23.6 0.0 0.00019 21.4 0.0 2.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain hEGF PF12661.2 EMC78205.1 - 0.29 11.2 89.4 0.087 12.9 1.6 9.7 9 0 0 9 9 9 0 Human growth factor-like EGF tRNA-synt_1d PF00750.14 EMC78206.1 - 1.5e-135 451.5 0.0 2.1e-135 451.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.11 EMC78206.1 - 5.7e-22 78.0 0.5 1.8e-21 76.4 0.1 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DALR_1 PF05746.10 EMC78206.1 - 2e-20 72.9 1.0 3.9e-20 72.0 0.1 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1e PF01406.14 EMC78206.1 - 0.019 14.1 0.3 0.09 11.8 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Microtub_assoc PF07989.6 EMC78206.1 - 0.02 14.6 0.5 0.085 12.6 0.3 2.0 1 0 0 1 1 1 0 Microtubule associated Homeobox PF00046.24 EMC78207.1 - 2.6e-22 78.1 5.1 2.9e-22 78.0 3.5 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC78207.1 - 0.00014 20.8 0.1 0.00017 20.5 0.1 1.1 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC78207.1 - 0.035 13.8 0.6 0.046 13.4 0.1 1.4 2 0 0 2 2 2 0 Homeobox KN domain Ribosomal_S7e PF01251.13 EMC78207.1 - 0.14 11.6 0.2 0.14 11.5 0.2 1.0 1 0 0 1 1 1 0 Ribosomal protein S7e I-set PF07679.11 EMC78209.1 - 1.8e-14 53.3 0.0 2.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Kazal_1 PF00050.16 EMC78209.1 - 3.8e-07 30.0 5.2 3.8e-07 30.0 3.6 2.7 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.1 EMC78209.1 - 7.1e-07 29.2 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC78209.1 - 1.7e-06 28.0 0.0 4.7e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC78209.1 - 6.5e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain IGFBP PF00219.13 EMC78209.1 - 0.0019 18.6 19.3 0.0019 18.6 13.4 2.3 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_2 PF07648.10 EMC78209.1 - 0.0026 17.6 4.3 0.0026 17.6 3.0 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Ig_3 PF13927.1 EMC78209.1 - 0.014 15.9 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Herpes_gE PF02480.11 EMC78209.1 - 0.14 10.4 4.2 0.19 9.9 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Neur_chan_LBD PF02931.18 EMC78210.1 - 4.1e-48 163.3 0.9 5.3e-48 163.0 0.0 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC78210.1 - 7.2e-27 94.8 11.3 9.2e-24 84.6 5.1 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region EF-hand_7 PF13499.1 EMC78211.1 - 8.2e-25 86.7 4.2 5.3e-15 55.2 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC78211.1 - 8.6e-19 65.3 5.9 3.4e-07 29.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC78211.1 - 1.5e-16 58.6 2.9 0.00018 21.0 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EMC78211.1 - 1.5e-15 56.5 3.5 0.00026 20.5 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC78211.1 - 7.3e-12 44.0 3.8 4.9e-05 22.4 0.0 3.5 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 EMC78211.1 - 1.5e-06 28.2 0.4 2.6e-05 24.2 0.1 2.7 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC78211.1 - 0.0014 18.3 1.8 0.056 13.1 0.1 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC78211.1 - 0.0042 16.9 0.2 6.7 6.7 0.0 3.8 3 1 0 3 3 3 1 EF-hand domain EF-hand_2 PF09068.6 EMC78211.1 - 0.0068 16.4 0.1 0.6 10.1 0.0 2.6 2 1 0 2 2 2 1 EF hand S10_plectin PF03501.10 EMC78211.1 - 0.011 15.6 0.1 0.023 14.5 0.1 1.6 1 1 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 EMC78211.1 - 0.012 15.2 0.4 3.9 7.2 0.0 3.0 3 0 0 3 3 3 0 EF hand CaKB PF03185.10 EMC78212.1 - 3.1e-82 274.8 0.3 3.6e-82 274.6 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit SH2 PF00017.19 EMC78213.1 - 8.3e-14 51.1 0.1 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SAM_2 PF07647.12 EMC78213.1 - 2.2e-11 43.4 0.0 3.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC78213.1 - 0.0028 17.7 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Daxx PF03344.10 EMC78213.1 - 0.33 9.3 6.9 0.51 8.7 4.8 1.2 1 0 0 1 1 1 0 Daxx Family Fork_head PF00250.13 EMC78214.1 - 1.4e-42 143.5 0.1 2.5e-42 142.8 0.1 1.4 1 0 0 1 1 1 1 Fork head domain DOCK-C2 PF14429.1 EMC78215.1 - 9.4e-52 175.3 0.1 3.3e-51 173.5 0.0 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EMC78215.1 - 3e-41 140.6 0.6 9.1e-41 139.0 0.0 2.2 2 0 0 2 2 2 1 Dedicator of cytokinesis SH3_9 PF14604.1 EMC78215.1 - 2.6e-06 26.9 0.0 5.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC78215.1 - 9.6e-06 24.8 0.0 1.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC78215.1 - 0.00013 21.3 0.1 0.00027 20.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain HSCB_C PF07743.8 EMC78215.1 - 6 7.4 12.3 7.1 7.1 0.1 4.5 4 1 1 5 5 5 0 HSCB C-terminal oligomerisation domain FAM196 PF15265.1 EMC78216.1 - 1.1e-176 589.0 29.9 1.2e-176 588.9 20.7 1.0 1 0 0 1 1 1 1 FAM196 family Spc7 PF08317.6 EMC78217.1 - 0.0029 16.3 22.1 0.0029 16.3 15.3 5.0 1 1 4 5 5 5 1 Spc7 kinetochore protein rve_3 PF13683.1 EMC78217.1 - 0.03 13.8 1.4 1.2 8.7 0.1 3.3 3 0 0 3 3 3 0 Integrase core domain LRR_8 PF13855.1 EMC78218.1 - 3.6e-74 244.4 62.7 2.3e-15 56.0 0.7 9.5 4 3 5 9 9 9 9 Leucine rich repeat EGF PF00008.22 EMC78218.1 - 2.2e-42 142.5 134.2 1.7e-06 27.8 3.3 12.1 11 0 0 11 11 10 9 EGF-like domain LRR_4 PF12799.2 EMC78218.1 - 1.1e-40 136.5 47.8 6.3e-07 28.8 1.2 10.5 7 3 3 11 11 11 10 Leucine Rich repeats (2 copies) Laminin_G_2 PF02210.19 EMC78218.1 - 2.4e-27 95.4 0.1 3.8e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EMC78218.1 - 3.6e-22 78.7 0.1 5.5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain LRR_1 PF00560.28 EMC78218.1 - 1.3e-18 64.1 41.8 0.35 11.0 0.0 16.6 19 0 0 19 19 19 8 Leucine Rich Repeat hEGF PF12661.2 EMC78218.1 - 7.9e-17 60.1 89.2 0.0018 18.2 1.6 12.0 10 0 0 10 10 9 8 Human growth factor-like EGF LRRNT PF01462.13 EMC78218.1 - 4.9e-15 54.5 28.9 9.1e-09 34.5 2.2 8.4 10 0 0 10 10 9 3 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 EMC78218.1 - 9.2e-09 35.0 17.0 0.0023 17.5 0.9 5.5 4 2 2 6 6 6 3 Leucine-rich repeat Laminin_G_3 PF13385.1 EMC78218.1 - 2.7e-05 24.4 0.0 4.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily LRR_6 PF13516.1 EMC78218.1 - 4e-05 23.2 37.3 1.1 9.5 0.1 13.8 11 5 2 13 13 13 2 Leucine Rich repeat Fumble PF03630.9 EMC78219.1 - 5.2e-145 482.5 0.0 6e-145 482.3 0.0 1.0 1 0 0 1 1 1 1 Fumble Imm11 PF15563.1 EMC78219.1 - 0.088 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 11 PID PF00640.18 EMC78220.1 - 6.9e-27 94.1 0.0 5.7e-24 84.6 0.0 2.3 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.21 EMC78220.1 - 3.7e-05 23.4 3.9 8.5e-05 22.3 2.7 1.7 1 0 0 1 1 1 1 WW domain PTB PF08416.8 EMC78220.1 - 7.5e-05 22.6 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SRA1 PF07304.6 EMC78221.1 - 4.9e-40 136.8 0.1 6.3e-40 136.4 0.1 1.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) RESP18 PF14948.1 EMC78221.1 - 0.06 13.3 0.1 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 RESP18 domain Se-cys_synth_N PF12390.3 EMC78221.1 - 0.21 11.7 2.9 3.2 7.9 0.1 2.6 2 1 0 2 2 2 0 Selenocysteine synthase N terminal HCO3_cotransp PF00955.16 EMC78222.1 - 2.2e-222 739.2 3.6 2.7e-222 738.9 2.5 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 EMC78222.1 - 5.7e-75 252.1 0.0 1.4e-74 250.8 0.0 1.7 1 1 0 1 1 1 1 Band 3 cytoplasmic domain EGF PF00008.22 EMC78223.1 - 1.2e-05 25.0 5.2 2.1e-05 24.3 3.6 1.4 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 EMC78223.1 - 0.00037 20.3 3.0 0.00086 19.2 2.1 1.7 1 0 0 1 1 1 1 Human growth factor-like EGF AP_endonuc_2 PF01261.19 EMC78223.1 - 0.054 12.7 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Laminin_EGF PF00053.19 EMC78223.1 - 1.8 8.5 5.3 3.8 7.5 3.7 1.6 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) Prefoldin_2 PF01920.15 EMC78224.1 - 2e-19 69.3 13.0 2.3e-19 69.1 9.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Lant_dehyd_C PF04738.8 EMC78224.1 - 0.015 13.5 0.8 0.021 13.0 0.3 1.2 1 1 0 1 1 1 0 Lantibiotic dehydratase, C terminus Mei5 PF10376.4 EMC78224.1 - 0.034 13.6 4.8 0.039 13.4 3.3 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein Sas10_Utp3 PF04000.10 EMC78224.1 - 1.1 9.5 5.6 3.9 7.7 3.3 2.0 1 1 1 2 2 2 0 Sas10/Utp3/C1D family Ax_dynein_light PF10211.4 EMC78224.1 - 2.2 8.0 11.4 2.9 7.6 2.2 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 EMC78224.1 - 2.5 8.1 9.6 3.7 7.6 0.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 EMC78224.1 - 3.7 7.4 14.9 4 7.3 3.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ING PF12998.2 EMC78224.1 - 3.7 7.8 9.1 24 5.2 6.3 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-CXXC PF02008.15 EMC78226.1 - 1.4e-07 31.1 23.5 2.3e-07 30.5 16.3 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain QueC PF06508.8 EMC78226.1 - 3.6 6.8 11.3 2.1 7.5 0.6 2.3 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC UQ_con PF00179.21 EMC78227.1 - 2.5e-47 159.8 0.1 2.8e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC78227.1 - 0.00018 21.2 0.0 0.00019 21.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC78227.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC78227.1 - 0.029 14.0 0.1 0.048 13.3 0.1 1.3 1 1 0 1 1 1 0 UEV domain TMEM173 PF15009.1 EMC78228.1 - 8.6e-68 228.3 0.3 9.9e-68 228.1 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 173 Acetyltransf_5 PF13444.1 EMC78228.1 - 0.077 13.5 0.1 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nuc_sug_transp PF04142.10 EMC78229.1 - 1.7e-41 141.9 16.2 2.1e-41 141.6 11.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EMC78229.1 - 0.017 15.1 2.1 0.017 15.1 1.5 3.1 2 2 1 3 3 3 0 EamA-like transporter family Oxidored_q1_N PF00662.15 EMC78229.1 - 2.6 7.6 7.3 5.2 6.6 1.1 3.2 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Atx10homo_assoc PF09759.4 EMC78230.1 - 0.0014 18.3 0.1 0.45 10.2 0.0 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.4 EMC78230.1 - 0.015 13.5 0.0 0.027 12.7 0.0 1.4 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit Arm PF00514.18 EMC78230.1 - 0.22 11.4 23.7 0.41 10.5 0.1 6.8 8 1 0 8 8 8 0 Armadillo/beta-catenin-like repeat RED_N PF07808.8 EMC78232.1 - 6.3e-92 307.1 15.3 6.3e-92 307.1 10.6 2.4 2 0 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.6 EMC78232.1 - 2.5e-51 172.8 7.7 2.5e-51 172.8 5.3 3.4 4 1 0 4 4 4 1 RED-like protein C-terminal region PRP38_assoc PF12871.2 EMC78232.1 - 0.0087 16.5 19.0 0.0087 16.5 13.2 3.5 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Lsm_interact PF05391.6 EMC78232.1 - 0.015 14.6 0.1 0.086 12.3 0.1 2.4 1 0 0 1 1 1 0 Lsm interaction motif DUF2749 PF10907.3 EMC78232.1 - 0.3 10.9 2.4 5.9 6.8 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) tRNA-synt_His PF13393.1 EMC78233.1 - 3.2e-43 147.9 0.0 4.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMC78233.1 - 2.1e-19 69.7 0.0 4.3e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC78233.1 - 2.7e-11 43.2 0.3 6.7e-11 41.9 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMC78233.1 - 0.0004 19.2 0.0 0.0057 15.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.15 EMC78233.1 - 0.015 14.9 0.4 0.037 13.6 0.3 1.7 1 0 0 1 1 1 0 WHEP-TRS domain tRNA-synt_2d PF01409.15 EMC78233.1 - 0.033 13.3 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_His PF13393.1 EMC78234.1 - 2.1e-28 99.2 0.0 1.5e-27 96.4 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 EMC78234.1 - 1.7e-16 59.9 0.1 3.2e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EMC78234.1 - 2.7e-11 43.3 0.0 1.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.2 EMC78234.1 - 0.00049 19.3 0.0 0.00068 18.8 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.15 EMC78234.1 - 0.061 12.0 0.0 0.84 8.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) zf-C2H2_jaz PF12171.3 EMC78235.1 - 6.4e-07 29.3 1.2 1.5e-06 28.1 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC78235.1 - 2.5e-06 27.4 1.3 4.1e-06 26.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 EMC78235.1 - 0.00013 21.4 1.0 0.00022 20.6 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF1777 PF08648.7 EMC78235.1 - 0.0031 17.2 12.1 0.0031 17.2 8.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Cgr1 PF03879.9 EMC78235.1 - 0.0058 16.7 18.0 0.0058 16.7 12.5 2.3 2 0 0 2 2 2 1 Cgr1 family CCDC84 PF14968.1 EMC78235.1 - 0.097 12.1 12.6 0.025 14.0 4.6 2.0 1 1 1 2 2 2 0 Coiled coil protein 84 CAF-1_p150 PF11600.3 EMC78235.1 - 0.89 8.8 31.8 0.019 14.3 12.7 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hex_IIIa PF02455.11 EMC78235.1 - 1.1 7.8 6.0 1.3 7.6 4.2 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF87 PF01935.12 EMC78235.1 - 2.5 7.8 6.6 3.3 7.4 4.6 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF3959 PF13105.1 EMC78235.1 - 4.1 6.6 6.3 6.8 5.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Caldesmon PF02029.10 EMC78235.1 - 8.8 4.6 26.2 0.21 9.9 11.7 1.9 2 0 0 2 2 2 0 Caldesmon Cadherin PF00028.12 EMC78236.1 - 3.8e-88 289.9 0.5 5.3e-19 68.2 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 EMC78236.1 - 7.6e-34 115.1 0.0 3.9e-30 103.2 0.0 4.4 5 0 0 5 5 5 2 Cadherin-like He_PIG PF05345.7 EMC78236.1 - 0.028 14.4 6.3 0.39 10.7 0.3 5.0 5 0 0 5 5 5 0 Putative Ig domain Cadherin PF00028.12 EMC78237.1 - 0 1341.4 9.2 5.7e-20 71.3 0.8 27.3 27 0 0 27 27 27 27 Cadherin domain Cadherin_2 PF08266.7 EMC78237.1 - 6.2e-07 28.9 0.1 12 5.5 0.0 10.2 13 0 0 13 13 13 1 Cadherin-like RRF PF01765.14 EMC78237.1 - 0.00082 18.8 0.2 22 4.4 0.0 4.3 4 0 0 4 4 4 1 Ribosome recycling factor DUF1117 PF06547.7 EMC78237.1 - 0.13 12.3 0.2 1.3e+02 2.6 0.0 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF1117) NUC153 PF08159.7 EMC78237.1 - 0.16 11.5 0.1 23 4.6 0.0 3.4 3 0 0 3 3 3 0 NUC153 domain ArsB PF02040.10 EMC78237.1 - 6.2 5.6 3.8 1.3e+02 1.3 0.0 3.7 5 0 0 5 5 5 0 Arsenical pump membrane protein Cadherin PF00028.12 EMC78241.1 - 0 1711.6 0.0 3.1e-19 69.0 0.0 34.9 34 1 0 34 34 34 34 Cadherin domain Cadherin_2 PF08266.7 EMC78241.1 - 3.2e-24 84.3 18.5 1.2e-07 31.1 0.3 17.0 24 1 0 24 24 24 4 Cadherin-like DUF3857 PF12969.2 EMC78241.1 - 0.0038 16.8 5.9 31 4.1 0.0 6.2 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3857) ChitinaseA_N PF08329.5 EMC78241.1 - 0.17 11.6 3.7 20 4.9 0.0 4.9 6 0 0 6 6 6 0 Chitinase A, N-terminal domain PapG_N PF03627.8 EMC78241.1 - 1.7 8.0 0.0 1.3e+03 -1.4 0.0 4.7 9 0 0 9 9 9 0 PapG carbohydrate binding domain Hist_deacetyl PF00850.14 EMC78242.1 - 2.5e-76 256.9 0.1 3.7e-76 256.3 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RELT PF12606.3 EMC78243.1 - 4.8e-18 64.0 0.8 4.8e-18 64.0 0.6 1.9 2 1 0 2 2 2 1 Tumour necrosis factor receptor superfamily member 19 SieB PF14163.1 EMC78243.1 - 0.033 13.7 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B CM_2 PF01817.16 EMC78243.1 - 0.093 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Chorismate mutase type II SH3_1 PF00018.23 EMC78244.1 - 4.6e-11 41.9 0.1 8.8e-11 41.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC78244.1 - 7.8e-08 31.6 0.1 1.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC78244.1 - 9.7e-07 28.2 0.1 2.2e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC78244.1 - 3.3e-05 23.9 0.1 5.9e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain hSH3 PF14603.1 EMC78244.1 - 0.0045 16.9 0.1 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Helically-extended SH3 domain 7tm_1 PF00001.16 EMC78245.1 - 6.9e-42 143.3 21.7 9.1e-42 142.9 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_I5 PF04713.7 EMC78245.1 - 0.36 10.5 6.3 0.81 9.4 4.3 1.6 1 0 0 1 1 1 0 Poxvirus protein I5 RhoGAP PF00620.22 EMC78246.1 - 7.1e-40 136.0 0.1 1.6e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EMC78246.1 - 4e-21 75.1 1.9 1.1e-05 25.6 0.1 5.5 6 0 0 6 6 6 3 PH domain ArfGap PF01412.13 EMC78246.1 - 8.9e-17 60.9 0.0 2.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAM_2 PF07647.12 EMC78246.1 - 3e-15 55.7 0.0 1.7e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC78246.1 - 2.1e-12 47.0 0.0 5.5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EMC78246.1 - 9.2e-12 45.2 0.0 2.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_3 PF14593.1 EMC78246.1 - 8e-05 22.4 0.0 0.0008 19.2 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_6 PF15406.1 EMC78246.1 - 0.00024 21.1 0.0 0.00075 19.5 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EMC78246.1 - 0.0011 19.1 1.4 4.5 7.5 0.0 4.0 5 0 0 5 5 5 2 Pleckstrin homology domain PH_8 PF15409.1 EMC78246.1 - 0.052 13.6 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain START PF01852.14 EMC78247.1 - 1.9e-23 82.8 0.0 2.5e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EMC78247.1 - 2.8e-06 27.0 0.0 1.1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Cadherin PF00028.12 EMC78248.1 - 4.6e-111 363.3 7.5 6.8e-23 80.7 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 EMC78248.1 - 4.6e-86 288.0 2.5 1.5e-85 286.3 1.7 1.9 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 EMC78248.1 - 2.4e-12 46.2 0.0 3.2e-05 23.4 0.0 5.7 6 0 0 6 6 6 2 Cadherin-like DUF1510 PF07423.6 EMC78248.1 - 0.0032 16.8 0.4 0.0063 15.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MLANA PF14991.1 EMC78248.1 - 0.032 14.2 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A EphA2_TM PF14575.1 EMC78248.1 - 0.073 13.4 0.1 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMC78248.1 - 0.075 13.1 1.1 0.11 12.7 0.0 1.7 2 0 0 2 2 1 0 Wnt and FGF inhibitory regulator Mid2 PF04478.7 EMC78248.1 - 0.081 12.3 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 EMC78248.1 - 0.12 10.6 0.0 0.2 9.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EMC78248.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain IncA PF04156.9 EMC78248.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 IncA protein Sel1 PF08238.7 EMC78249.1 - 1.9e-26 91.8 18.1 2e-08 34.6 0.1 5.2 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.1 EMC78249.1 - 0.0012 19.1 3.4 3.3 8.3 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC78249.1 - 0.043 14.5 10.8 6.4 7.5 0.0 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC78249.1 - 0.37 10.4 11.0 7.7 6.2 0.3 3.9 1 1 3 4 4 4 0 TPR repeat m04gp34like PF12216.3 EMC78250.1 - 0.13 11.5 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein P3A PF08727.6 EMC78250.1 - 0.4 10.0 3.3 7.1 6.0 0.0 2.3 1 1 1 2 2 2 0 Poliovirus 3A protein like ABC2_membrane_3 PF12698.2 EMC78251.1 - 0.0038 16.2 0.1 0.0043 16.1 0.1 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF912 PF06024.7 EMC78251.1 - 0.067 13.2 0.1 0.093 12.7 0.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 EMC78251.1 - 0.072 12.5 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Shisa PF13908.1 EMC78251.1 - 0.087 13.0 16.9 0.11 12.6 2.9 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 EMC78251.1 - 0.35 10.5 8.4 1.1 8.9 5.8 1.8 1 1 0 1 1 1 0 TMEM154 protein family Xan_ur_permease PF00860.15 EMC78252.1 - 7.8e-85 284.7 23.1 9.7e-85 284.3 16.0 1.1 1 0 0 1 1 1 1 Permease family MerE PF05052.7 EMC78252.1 - 0.23 11.4 3.0 0.21 11.5 0.1 2.5 3 0 0 3 3 3 0 MerE protein PAM2 PF07145.10 EMC78253.1 - 9.7e-08 31.0 0.8 3e-07 29.4 0.5 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RE_HindIII PF09518.5 EMC78253.1 - 0.023 13.6 1.5 0.028 13.3 1.1 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease rve_3 PF13683.1 EMC78253.1 - 0.27 10.7 1.5 1.4 8.4 0.5 2.0 1 1 1 2 2 2 0 Integrase core domain RRM_5 PF13893.1 EMC78254.1 - 5.2e-28 96.6 0.0 3.4e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78254.1 - 1.3e-19 69.8 0.0 1.4e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC78254.1 - 7.2e-09 35.1 0.0 0.0005 19.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EMC78254.1 - 0.13 12.4 7.3 0.15 12.2 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC78254.1 - 4.3 7.6 10.3 8.1 6.8 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Fes1 PF08609.5 EMC78255.1 - 0.0038 17.6 2.8 0.006 17.0 1.1 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 CDC14 PF08045.6 EMC78255.1 - 0.0049 16.0 5.3 0.074 12.1 0.2 3.0 1 1 2 3 3 3 1 Cell division control protein 14, SIN component V-ATPase_H_C PF11698.3 EMC78255.1 - 0.0063 16.4 0.6 0.15 12.0 0.0 2.8 2 1 1 3 3 3 1 V-ATPase subunit H DUF812 PF05667.6 EMC78255.1 - 0.016 13.7 4.3 0.024 13.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Rab5-bind PF09311.6 EMC78255.1 - 0.017 15.0 3.5 0.017 15.0 2.4 2.1 2 1 0 2 2 2 0 Rabaptin-like protein BMFP PF04380.8 EMC78255.1 - 0.025 14.7 3.3 0.06 13.4 2.3 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity HEAT_EZ PF13513.1 EMC78255.1 - 0.025 15.0 0.2 0.1 13.1 0.1 2.2 1 0 0 1 1 1 0 HEAT-like repeat HEAT_2 PF13646.1 EMC78255.1 - 0.037 14.2 0.2 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats Dispanin PF04505.7 EMC78256.1 - 0.17 11.4 2.3 0.29 10.7 1.6 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Vinculin PF01044.14 EMC78257.1 - 0 1038.1 37.4 3.9e-215 716.9 16.8 2.1 1 1 1 2 2 2 2 Vinculin family DivIC PF04977.10 EMC78257.1 - 6 6.4 8.5 0.77 9.2 0.5 3.5 3 0 0 3 3 3 0 Septum formation initiator LRR_8 PF13855.1 EMC78258.1 - 4.6e-45 151.1 51.9 1.5e-13 50.2 7.4 5.2 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EMC78258.1 - 1.9e-30 103.9 40.8 6.7e-07 28.7 0.8 6.8 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC78258.1 - 3.4e-22 78.5 0.4 2.4e-09 37.0 0.0 3.2 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC78258.1 - 1.9e-20 69.7 32.4 0.014 15.2 1.0 10.6 10 1 0 10 10 10 8 Leucine Rich Repeat LRR_9 PF14580.1 EMC78258.1 - 5.4e-08 32.5 5.9 0.07 12.6 0.2 4.0 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 EMC78258.1 - 2.6e-07 29.7 41.2 1 9.8 0.5 10.8 11 0 0 11 11 11 5 Leucine rich repeat LRR_6 PF13516.1 EMC78258.1 - 4.7e-07 29.2 38.0 0.48 10.6 0.9 10.0 10 1 1 11 11 11 3 Leucine Rich repeat LRRNT PF01462.13 EMC78258.1 - 0.0045 16.4 1.8 0.0045 16.4 1.3 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain eRF1_2 PF03464.10 EMC78259.1 - 1.1e-45 155.1 0.1 1.7e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMC78259.1 - 3.6e-39 133.5 0.3 7.7e-39 132.4 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EMC78259.1 - 3.2e-23 81.7 0.0 5.8e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EMC78259.1 - 0.0044 16.4 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.27 EMC78260.1 - 1.9e-57 189.1 15.7 2.2e-09 36.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 EMC78260.1 - 5.9e-28 96.1 2.3 1.1e-27 95.2 1.6 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 EMC78260.1 - 1.5e-09 37.4 0.2 3.8e-09 36.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC78260.1 - 1.4e-07 30.9 0.0 4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EMC78260.1 - 5.9e-05 21.9 3.5 0.011 14.4 0.0 3.6 1 1 3 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 EMC78260.1 - 0.03 12.4 6.9 2.3 6.2 0.1 3.8 1 1 2 4 4 4 0 Nucleoporin Nup120/160 DUF4508 PF14969.1 EMC78260.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) FGF PF00167.13 EMC78262.1 - 3.6e-29 101.0 0.0 5.1e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Nucleoplasmin PF03066.10 EMC78263.1 - 7.3e-44 148.8 28.0 5.5e-43 146.0 19.4 2.4 1 1 0 1 1 1 1 Nucleoplasmin TFIIF_alpha PF05793.7 EMC78263.1 - 2.4e-05 22.9 18.2 2.4e-05 22.8 12.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.6 EMC78263.1 - 0.0005 18.5 8.3 0.00062 18.2 5.7 1.3 1 0 0 1 1 1 1 SGT1 protein CENP-T PF15511.1 EMC78263.1 - 0.00079 18.7 9.7 0.0008 18.7 6.7 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T MalF_P2 PF14785.1 EMC78263.1 - 0.028 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Nop14 PF04147.7 EMC78263.1 - 0.064 11.1 28.4 0.092 10.6 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EMC78263.1 - 0.8 8.9 21.0 1.4 8.1 14.6 1.3 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 EMC78263.1 - 0.99 7.0 4.8 1.2 6.7 3.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EMC78263.1 - 1.4 6.8 13.0 2 6.3 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EMC78263.1 - 1.4 8.0 14.8 2.8 7.1 10.3 1.5 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EMC78263.1 - 2.5 6.4 22.9 3.5 5.9 15.8 1.2 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 EMC78263.1 - 7.2 4.5 6.5 10 4.0 4.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SUD-M PF11633.3 EMC78264.1 - 0.00015 21.0 0.2 16 4.8 0.0 4.1 4 0 0 4 4 4 3 Single-stranded poly(A) binding domain tRNA_int_end_N2 PF12928.2 EMC78264.1 - 0.0038 16.6 3.6 15 5.1 0.0 4.7 3 2 2 5 5 5 2 tRNA-splicing endonuclease subunit sen54 N-term Smac_DIABLO PF09057.5 EMC78264.1 - 0.96 8.5 12.5 5 6.1 0.9 3.3 1 1 2 3 3 3 0 Second Mitochondria-derived Activator of Caspases Defensin_beta PF00711.14 EMC78265.1 - 2.8e-07 30.3 13.5 3.6e-07 29.9 9.3 1.2 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 EMC78265.1 - 0.00063 19.6 0.4 0.00068 19.5 0.3 1.1 1 0 0 1 1 1 1 Defensin propeptide Defensin_beta PF00711.14 EMC78266.1 - 6e-10 38.8 13.5 7e-10 38.6 9.3 1.1 1 0 0 1 1 1 1 Beta defensin Ornatin PF02088.10 EMC78266.1 - 0.062 12.8 2.0 0.062 12.8 1.4 1.9 1 1 1 2 2 2 0 Ornatin Toxin_23 PF08093.6 EMC78266.1 - 0.82 9.6 5.8 0.5 10.3 0.6 2.2 2 0 0 2 2 2 0 Magi 5 toxic peptide family Defensin_beta PF00711.14 EMC78267.1 - 1.4e-07 31.2 10.2 1.7e-07 31.0 7.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.14 EMC78268.1 - 3.8e-07 29.9 11.5 4.4e-07 29.7 8.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 EMC78268.1 - 0.037 13.9 0.3 0.043 13.7 0.2 1.1 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.14 EMC78269.1 - 5.2e-07 29.4 10.9 6.2e-07 29.2 7.6 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.14 EMC78270.1 - 5.1e-07 29.5 9.5 6.1e-07 29.2 6.6 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.14 EMC78271.1 - 3.3e-11 42.9 8.1 3.9e-11 42.6 5.6 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_big PF14862.1 EMC78271.1 - 0.016 15.2 0.8 0.018 15.1 0.5 1.2 1 0 0 1 1 1 0 Big defensin Defensin_propep PF00879.13 EMC78271.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.14 EMC78272.1 - 5e-09 35.9 5.7 5.8e-09 35.7 3.9 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_1 PF00323.14 EMC78272.1 - 2.8 8.3 6.4 1.2 9.6 2.2 2.0 2 1 0 2 2 2 0 Mammalian defensin Defensin_beta PF00711.14 EMC78273.1 - 2.3e-05 24.2 25.5 6.9e-05 22.6 6.2 2.6 2 1 0 2 2 2 2 Beta defensin Inhibitor_I68 PF10468.4 EMC78273.1 - 0.073 13.2 10.2 0.092 12.9 7.1 1.1 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 Myotoxins PF00819.12 EMC78273.1 - 0.49 10.4 24.9 0.42 10.7 4.7 2.9 2 1 0 2 2 2 0 Myotoxin Defensin_beta PF00711.14 EMC78274.1 - 8.7e-06 25.5 7.4 8.7e-06 25.5 5.1 1.4 2 0 0 2 2 2 1 Beta defensin Defensin_beta_2 PF13841.1 EMC78274.1 - 0.00015 22.0 6.5 0.00022 21.5 4.5 1.2 1 0 0 1 1 1 1 Beta defensin Defensin_1 PF00323.14 EMC78274.1 - 0.12 12.7 1.5 0.12 12.7 1.1 2.0 2 0 0 2 2 2 0 Mammalian defensin Defensin_beta PF00711.14 EMC78275.1 - 4.6e-10 39.2 13.0 5.4e-10 39.0 9.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_big PF14862.1 EMC78275.1 - 5.2e-05 23.2 3.3 5.5e-05 23.1 2.3 1.1 1 0 0 1 1 1 1 Big defensin Defensin_beta_2 PF13841.1 EMC78275.1 - 0.27 11.6 13.0 0.43 10.9 9.0 1.4 1 0 0 1 1 1 0 Beta defensin Gamma-thionin PF00304.15 EMC78275.1 - 0.34 10.9 11.3 0.44 10.5 7.8 1.1 1 0 0 1 1 1 0 Gamma-thionin family Peptidase_C1 PF00112.18 EMC78276.1 - 3.2e-67 226.6 2.2 3.8e-67 226.3 1.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 EMC78276.1 - 1.6e-18 66.0 0.1 3.2e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 EMC78276.1 - 0.08 11.4 1.1 3 6.2 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family SQS_PSY PF00494.14 EMC78277.1 - 6.2e-44 150.2 0.0 8.3e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase H2TH PF06831.9 EMC78278.1 - 1.3e-13 50.4 0.0 1.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.9 EMC78278.1 - 0.0099 15.5 0.1 0.022 14.4 0.1 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-C3HC4 PF00097.20 EMC78279.1 - 2.1e-11 43.2 10.3 3e-11 42.7 7.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC78279.1 - 1.3e-09 37.7 8.5 2e-09 37.1 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC78279.1 - 7.7e-09 35.4 9.4 1.1e-08 34.9 6.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC78279.1 - 3e-07 29.9 8.5 4e-07 29.5 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC78279.1 - 3.5e-06 26.6 8.9 5.3e-06 26.0 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC78279.1 - 8.5e-06 25.5 8.4 1.4e-05 24.8 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EMC78279.1 - 8.7e-06 25.1 5.8 1.2e-05 24.7 4.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EMC78279.1 - 4.4e-05 22.9 6.7 9e-05 21.9 4.6 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EMC78279.1 - 0.00024 20.8 4.4 0.00037 20.2 3.0 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMC78279.1 - 0.0015 18.2 5.7 0.0037 16.9 4.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EMC78279.1 - 0.0022 17.4 7.4 0.0033 16.8 5.1 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EMC78279.1 - 0.014 15.4 6.0 0.042 13.9 4.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-UDP PF14569.1 EMC78279.1 - 0.029 14.1 3.2 0.048 13.4 2.2 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-C4_Topoisom PF01396.14 EMC78279.1 - 0.059 12.8 0.8 0.059 12.8 0.5 1.9 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-Apc11 PF12861.2 EMC78279.1 - 0.081 12.7 3.6 0.17 11.7 2.5 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EMC78279.1 - 0.46 10.3 7.1 7.2 6.5 4.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon DUF329 PF03884.9 EMC78279.1 - 0.73 9.4 6.8 0.91 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) DUF1272 PF06906.6 EMC78279.1 - 1 9.2 6.8 2.3 8.1 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.7 EMC78279.1 - 1.6 8.5 7.6 5.5 6.8 5.3 1.9 1 1 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.5 EMC78279.1 - 1.6 8.7 5.2 3.5 7.6 1.7 2.4 2 1 0 2 2 2 0 Zinc ribbon domain Glyco_transf_25 PF01755.12 EMC78280.1 - 1.4e-06 28.1 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-C3HC4 PF00097.20 EMC78281.1 - 3.9e-11 42.4 9.1 6e-11 41.8 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC78281.1 - 1.5e-09 37.4 9.9 2.3e-09 36.8 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC78281.1 - 3.5e-09 36.2 6.2 5.2e-09 35.6 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC78281.1 - 6.5e-09 35.6 10.3 1e-08 35.0 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC78281.1 - 3.2e-07 29.9 6.4 4.8e-07 29.3 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC78281.1 - 0.00023 21.2 8.3 0.00052 20.0 5.8 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC78281.1 - 0.0045 16.6 2.5 0.011 15.4 1.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMC78281.1 - 0.058 13.2 2.9 0.11 12.3 2.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 EMC78281.1 - 0.19 11.4 5.0 0.29 10.8 3.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EMC78281.1 - 0.38 10.6 11.0 0.64 9.9 7.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EMC78281.1 - 0.64 9.8 3.5 1.1 9.0 2.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-H2C2_2 PF13465.1 EMC78282.1 - 6.8e-253 805.8 214.5 1.2e-08 34.8 0.3 35.5 36 0 0 36 36 36 35 Zinc-finger double domain zf-C2H2 PF00096.21 EMC78282.1 - 4.8e-189 602.0 270.3 1.6e-06 28.0 0.9 35.1 35 0 0 35 35 35 35 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC78282.1 - 1.8e-86 278.3 241.0 0.0058 16.8 0.2 34.8 35 0 0 35 35 35 33 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC78282.1 - 1e-56 187.2 199.3 0.0004 20.1 0.3 35.1 35 0 0 35 35 35 24 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC78282.1 - 1.5e-32 110.9 136.6 0.00051 20.1 0.1 32.2 33 0 0 33 33 33 7 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.6 EMC78282.1 - 2.9e-16 58.8 185.1 1.1 9.0 0.5 33.3 34 0 0 34 34 34 11 LYAR-type C2HC zinc finger LIM PF00412.17 EMC78282.1 - 1e-14 54.3 174.7 0.42 10.7 1.2 27.5 7 6 19 28 28 28 7 LIM domain zf-trcl PF13451.1 EMC78282.1 - 7e-14 51.1 156.5 0.76 9.4 0.1 32.6 33 1 0 33 33 33 6 Probable zinc-binding domain Imm-NTF2-2 PF15631.1 EMC78282.1 - 1.3e-13 50.6 0.0 2.3 8.2 0.0 18.0 16 6 15 31 31 30 1 NTF2 fold immunity protein Zn-ribbon_8 PF09723.5 EMC78282.1 - 3e-13 49.4 172.9 0.18 11.7 1.4 27.6 7 4 23 30 30 30 15 Zinc ribbon domain CpXC PF14353.1 EMC78282.1 - 1.5e-09 37.9 125.7 0.84 9.6 0.7 27.8 6 4 20 29 29 29 5 CpXC protein DUF2423 PF10338.4 EMC78282.1 - 6.3e-08 32.4 10.3 21 5.1 0.0 7.7 7 0 0 7 7 7 0 Protein of unknown function (DUF2423) BHD_1 PF10403.4 EMC78282.1 - 7.1e-06 25.4 0.5 7.6 6.1 0.0 8.2 11 0 0 11 11 6 0 Rad4 beta-hairpin domain 1 YhfH PF14149.1 EMC78282.1 - 7.7e-06 25.5 111.6 4.7 7.0 0.1 28.1 28 1 2 30 30 30 1 YhfH-like protein Phage_stabilise PF11134.3 EMC78282.1 - 0.0031 16.1 4.3 34 2.8 0.0 6.8 6 3 3 9 9 9 0 Phage stabilisation protein zf-met PF12874.2 EMC78282.1 - 0.02 15.0 0.4 0.02 15.0 0.3 31.3 33 0 0 33 33 33 0 Zinc-finger of C2H2 type TFIIS_C PF01096.13 EMC78282.1 - 0.067 12.8 163.6 8.4 6.1 0.4 32.3 34 0 0 34 34 34 0 Transcription factor S-II (TFIIS) DUF1635 PF07795.6 EMC78282.1 - 0.88 8.9 24.0 43 3.3 0.0 11.3 7 4 10 18 18 18 0 Protein of unknown function (DUF1635) zf-ISL3 PF14690.1 EMC78282.1 - 3.4 7.7 147.1 10 6.2 0.3 31.2 31 3 2 33 33 33 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-AN1 PF01428.11 EMC78282.1 - 7.9 6.4 203.5 3.2 7.6 1.4 32.9 28 5 5 33 33 32 0 AN1-like Zinc finger KRAB PF01352.22 EMC78283.1 - 3.6e-19 67.9 0.1 4e-19 67.7 0.1 1.0 1 0 0 1 1 1 1 KRAB box Zds_C PF08632.5 EMC78283.1 - 0.046 13.1 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Amidohydro_1 PF01979.15 EMC78284.1 - 9.6e-15 55.0 0.0 1.5e-14 54.3 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC78284.1 - 4e-06 27.0 0.0 6.6e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC78284.1 - 0.00017 20.9 0.0 0.00024 20.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.9 EMC78284.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase DUF497 PF04365.8 EMC78284.1 - 0.041 13.7 0.1 0.27 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF497) AP_endonuc_2 PF01261.19 EMC78284.1 - 0.094 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Usp PF00582.21 EMC78284.1 - 0.15 12.2 0.5 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Universal stress protein family DUF1279 PF06916.8 EMC78285.1 - 2e-24 85.7 0.6 4.4e-24 84.6 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) LEA_4 PF02987.11 EMC78285.1 - 5.7e-06 26.0 10.2 5.7e-06 26.0 7.1 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.13 EMC78285.1 - 0.00036 20.0 0.7 0.00059 19.3 0.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EMC78285.1 - 0.0072 16.6 9.5 0.019 15.3 6.6 1.6 1 0 0 1 1 1 1 YtxH-like protein ISG65-75 PF11727.3 EMC78285.1 - 0.023 13.7 2.2 0.034 13.2 1.5 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Mit_KHE1 PF10173.4 EMC78285.1 - 0.038 13.8 0.5 0.067 13.0 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related AAA_28 PF13521.1 EMC78285.1 - 0.04 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.8 EMC78285.1 - 0.21 11.9 0.9 0.39 11.1 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Phe_tRNA-synt_N PF02912.13 EMC78285.1 - 0.51 10.1 4.2 0.98 9.1 2.5 1.7 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain CAAD PF14159.1 EMC78285.1 - 0.87 9.2 2.7 0.75 9.4 0.2 2.0 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase UBA_2 PF08587.6 EMC78285.1 - 3.3 7.9 6.2 2.5e+02 1.9 4.0 2.9 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) CD34_antigen PF06365.7 EMC78286.1 - 0.0014 18.2 1.0 0.0027 17.3 0.7 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.1 EMC78286.1 - 0.017 14.8 1.0 0.041 13.6 0.3 1.8 2 0 0 2 2 2 0 TMEM154 protein family Shisa PF13908.1 EMC78286.1 - 0.029 14.5 0.6 0.029 14.5 0.4 2.1 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator m04gp34like PF12216.3 EMC78286.1 - 0.044 13.1 0.5 0.094 12.0 0.2 1.6 2 0 0 2 2 2 0 Immune evasion protein Lig_chan PF00060.21 EMC78286.1 - 0.08 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel Rifin_STEVOR PF02009.11 EMC78286.1 - 1.4 8.4 3.5 2 7.9 2.4 1.1 1 0 0 1 1 1 0 Rifin/stevor family Motile_Sperm PF00635.21 EMC78287.1 - 3.2e-08 33.1 0.1 0.00095 18.7 0.0 4.6 4 1 0 4 4 4 2 MSP (Major sperm protein) domain MYCBPAP PF14646.1 EMC78287.1 - 7.4e-07 28.2 0.2 0.065 11.9 0.0 4.1 4 0 0 4 4 4 2 MYCBP-associated protein family WD40 PF00400.27 EMC78290.1 - 2.9e-27 93.4 27.6 2.5e-07 30.2 1.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Y_phosphatase PF00102.22 EMC78291.1 - 4.3e-76 255.3 0.1 4.3e-76 255.3 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC78291.1 - 0.0036 16.8 0.8 0.026 14.1 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC78291.1 - 0.055 13.5 3.6 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Inositol hexakisphosphate XLF PF09302.6 EMC78291.1 - 0.061 13.1 1.9 0.093 12.5 0.2 1.9 1 1 1 2 2 2 0 XLF (XRCC4-like factor) DUF1885 PF08968.5 EMC78291.1 - 0.076 12.6 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1885) PAC2 PF09754.4 EMC78292.1 - 1.4e-38 132.9 0.0 1.9e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 PAC2 family CEP76-C2 PF15627.1 EMC78293.1 - 2.6e-54 183.0 0.0 4.7e-54 182.1 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.14 EMC78293.1 - 0.0037 17.4 0.1 0.0081 16.3 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core3 PF13471.1 EMC78293.1 - 0.03 14.1 0.3 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Muted PF14942.1 EMC78294.1 - 0.041 13.7 1.9 8.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein WH2 PF02205.15 EMC78294.1 - 0.091 12.3 1.2 7.3 6.3 0.3 3.7 4 0 0 4 4 4 0 WH2 motif FYVE PF01363.16 EMC78294.1 - 0.63 9.9 14.8 1.6 8.6 10.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger Peptidase_M41 PF01434.13 EMC78295.1 - 7e-74 247.8 0.1 9.5e-74 247.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMC78295.1 - 1.5e-42 144.9 0.0 3.2e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EMC78295.1 - 4.9e-09 36.3 1.3 1e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 EMC78295.1 - 0.00015 21.9 0.1 0.0089 16.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC78295.1 - 0.0005 19.8 0.0 0.0022 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMC78295.1 - 0.00079 20.2 0.0 0.0029 18.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC78295.1 - 0.001 18.2 0.1 0.011 14.8 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 EMC78295.1 - 0.0011 18.8 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EMC78295.1 - 0.0021 17.7 1.3 0.0063 16.2 0.9 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMC78295.1 - 0.003 16.6 0.1 0.01 14.9 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMC78295.1 - 0.0032 17.3 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMC78295.1 - 0.0048 15.6 0.0 0.0087 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EMC78295.1 - 0.0089 16.0 0.5 0.13 12.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EMC78295.1 - 0.013 14.9 0.2 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EMC78295.1 - 0.031 13.7 0.5 0.071 12.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EMC78295.1 - 0.068 12.3 0.2 0.23 10.6 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EMC78295.1 - 0.082 13.2 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMC78295.1 - 0.086 12.7 0.3 0.34 10.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EMC78295.1 - 0.086 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EMC78295.1 - 0.14 11.3 0.5 0.36 10.0 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Tubulin PF00091.20 EMC78296.1 - 2.3e-54 184.4 0.0 3.8e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC78296.1 - 4.4e-49 165.7 0.1 7.9e-49 164.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC78296.1 - 0.0089 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CIDE-N PF02017.10 EMC78297.1 - 6.1e-34 115.6 0.0 1.2e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 CIDE-N domain GCV_T PF01571.16 EMC78297.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Inositol_P PF00459.20 EMC78298.1 - 2e-73 247.0 0.1 2.2e-73 246.9 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TMF_DNA_bd PF12329.3 EMC78299.1 - 1.1e-05 25.1 24.6 0.001 18.7 4.1 2.8 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EMC78299.1 - 0.00086 18.7 3.1 0.00086 18.7 2.2 3.3 2 2 2 4 4 4 1 Septum formation initiator Myosin_tail_1 PF01576.14 EMC78299.1 - 0.0028 15.4 15.3 0.0034 15.1 10.6 1.0 1 0 0 1 1 1 1 Myosin tail TMF_TATA_bd PF12325.3 EMC78299.1 - 0.0085 15.8 16.3 0.018 14.7 3.2 2.3 1 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF4047 PF13256.1 EMC78299.1 - 0.01 15.8 2.4 0.01 15.8 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Seryl_tRNA_N PF02403.17 EMC78299.1 - 0.023 14.7 14.6 0.038 13.9 2.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.4 EMC78299.1 - 0.037 13.8 16.1 0.038 13.8 3.2 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF720 PF05302.6 EMC78299.1 - 0.039 13.7 0.3 0.17 11.6 0.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF720) DUF1664 PF07889.7 EMC78299.1 - 0.11 12.3 7.0 2.2 8.0 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) CDC37_N PF03234.9 EMC78299.1 - 0.11 12.7 12.2 0.16 12.3 7.0 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF3510 PF12022.3 EMC78299.1 - 0.13 12.3 3.0 0.12 12.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Serpin PF00079.15 EMC78299.1 - 0.13 11.3 1.0 0.14 11.2 0.7 1.2 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) DUF4140 PF13600.1 EMC78299.1 - 0.14 12.6 11.4 0.12 12.8 0.5 2.5 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) SUKH-4 PF14435.1 EMC78299.1 - 0.15 11.7 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein Filament PF00038.16 EMC78299.1 - 0.19 11.1 17.4 0.031 13.7 3.2 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF1875 PF08961.5 EMC78299.1 - 0.27 10.5 7.6 0.042 13.1 2.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) Peptidase_S64 PF08192.6 EMC78299.1 - 0.27 9.5 3.0 0.3 9.3 2.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 HALZ PF02183.13 EMC78299.1 - 0.33 10.7 9.2 0.19 11.4 3.8 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF445 PF04286.7 EMC78299.1 - 0.35 10.3 6.0 0.56 9.6 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Mod_r PF07200.8 EMC78299.1 - 0.36 10.7 14.1 0.95 9.3 4.0 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2935 PF11155.3 EMC78299.1 - 0.42 10.6 7.3 3 7.9 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF904 PF06005.7 EMC78299.1 - 0.5 10.7 26.1 1.6 9.0 7.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 EMC78299.1 - 0.58 10.1 27.2 0.86 9.5 3.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF4618 PF15397.1 EMC78299.1 - 0.68 9.2 13.8 0.45 9.7 1.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Nup54 PF13874.1 EMC78299.1 - 0.83 9.3 9.9 0.82 9.3 0.6 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DASH_Duo1 PF08651.5 EMC78299.1 - 0.86 9.2 5.5 2.4 7.8 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF1798 PF08807.5 EMC78299.1 - 0.88 9.3 5.1 0.27 10.9 0.3 2.1 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) RICH PF05062.7 EMC78299.1 - 0.91 9.7 16.7 0.22 11.6 4.5 2.3 2 0 0 2 2 2 0 RICH domain Phage_GP20 PF06810.6 EMC78299.1 - 0.95 8.8 13.9 0.51 9.7 2.6 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 GAS PF13851.1 EMC78299.1 - 1.1 8.4 20.6 0.87 8.7 5.1 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EMC78299.1 - 1.1 8.9 18.7 2.1 8.0 3.6 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.6 EMC78299.1 - 1.3 8.9 12.6 5.1 7.0 3.6 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p BLOC1_2 PF10046.4 EMC78299.1 - 1.4 9.1 12.6 3.3 7.9 2.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 EMC78299.1 - 1.4 7.7 19.8 0.22 10.4 2.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2664 PF10867.3 EMC78299.1 - 1.7 9.3 5.9 1.1 9.9 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) ADIP PF11559.3 EMC78299.1 - 2 8.3 20.1 1.3 8.9 4.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EMC78299.1 - 2 8.7 16.7 0.34 11.2 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Herpes_UL6 PF01763.11 EMC78299.1 - 2.1 6.4 10.9 1.1 7.3 5.1 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like APG6 PF04111.7 EMC78299.1 - 2.1 7.3 19.9 0.24 10.3 5.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 K-box PF01486.12 EMC78299.1 - 2.1 8.1 16.2 0.15 11.9 3.5 2.6 2 1 0 2 2 2 0 K-box region ATG16 PF08614.6 EMC78299.1 - 2.2 8.0 20.1 3.4 7.4 5.2 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PsbQ PF05757.6 EMC78299.1 - 2.5 7.4 6.7 0.38 10.1 0.9 2.2 2 1 1 3 3 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Cortex-I_coil PF09304.5 EMC78299.1 - 3.1 7.9 16.0 0.37 10.8 1.6 2.5 2 1 0 2 2 2 0 Cortexillin I, coiled coil Laminin_I PF06008.9 EMC78299.1 - 3.2 6.9 14.2 6.7 5.9 9.9 1.5 1 1 0 1 1 1 0 Laminin Domain I IncA PF04156.9 EMC78299.1 - 3.3 7.2 21.4 0.77 9.3 5.3 2.1 1 1 1 2 2 2 0 IncA protein DUF3450 PF11932.3 EMC78299.1 - 3.3 6.8 9.7 1.3 8.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIVA PF05103.8 EMC78299.1 - 5.4 7.0 17.0 1.9 8.5 4.1 2.9 1 1 1 2 2 2 0 DivIVA protein Bacillus_HBL PF05791.6 EMC78299.1 - 5.7 6.2 8.8 2.1 7.6 1.3 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TSC22 PF01166.13 EMC78299.1 - 5.9 6.9 14.9 5.8 6.9 0.1 3.3 3 1 0 3 3 3 0 TSC-22/dip/bun family Med21 PF11221.3 EMC78299.1 - 6.2 6.7 16.7 4.7 7.1 1.4 3.1 2 1 1 3 3 3 0 Subunit 21 of Mediator complex IpaC_SipC PF09599.5 EMC78299.1 - 6.5 5.6 9.2 10 5.0 0.5 1.9 1 1 1 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) HAP1_N PF04849.8 EMC78299.1 - 7.1 5.4 17.5 26 3.6 12.1 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Herpes_BLRF2 PF05812.7 EMC78299.1 - 8.2 6.2 12.6 2 8.2 0.3 2.7 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Uds1 PF15456.1 EMC78299.1 - 9.7 6.2 17.6 1.8 8.5 1.7 2.9 2 1 0 2 2 2 0 Up-regulated During Septation Metallophos PF00149.23 EMC78300.1 - 7.4e-10 38.5 0.5 2.2e-08 33.7 0.3 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC78300.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Varsurf_PPLC PF03490.8 EMC78300.1 - 0.034 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C SNAP PF14938.1 EMC78301.1 - 6.2e-26 91.1 12.4 8.4e-26 90.7 8.6 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 EMC78301.1 - 0.00028 21.2 12.4 1.7 9.4 0.8 5.8 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC78301.1 - 0.0012 18.4 15.8 0.1 12.2 0.1 4.5 1 1 3 4 4 4 1 TPR repeat DUF2150 PF09920.4 EMC78301.1 - 0.029 13.9 0.5 0.32 10.5 0.0 2.5 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_12 PF13424.1 EMC78301.1 - 0.048 13.5 0.2 0.048 13.5 0.1 4.4 1 1 3 4 4 4 0 Tetratricopeptide repeat NSF PF02071.15 EMC78301.1 - 0.066 13.7 14.1 1 10.1 0.3 5.6 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat Sec5 PF15469.1 EMC78301.1 - 0.083 12.6 1.0 4.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 UPF0449 PF15136.1 EMC78301.1 - 2.8 8.2 5.9 2.7 8.2 0.1 2.8 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 TPR_6 PF13174.1 EMC78301.1 - 8.2 7.1 11.7 83 3.9 0.1 5.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Laminin_G_2 PF02210.19 EMC78302.1 - 1.8e-91 302.8 9.7 4.2e-28 97.9 0.9 4.3 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.18 EMC78302.1 - 3.9e-66 221.0 0.9 2.3e-18 66.4 0.0 4.3 4 0 0 4 4 4 4 Laminin G domain F5_F8_type_C PF00754.20 EMC78302.1 - 1.7e-28 98.9 3.1 2.7e-28 98.3 0.2 2.7 3 0 0 3 3 3 1 F5/8 type C domain Laminin_G_3 PF13385.1 EMC78302.1 - 4.4e-13 49.7 2.1 0.00041 20.6 0.0 4.8 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 EMC78302.1 - 0.0015 18.4 8.3 0.0015 18.4 5.8 3.9 4 0 0 4 4 4 2 EGF-like domain EGF_2 PF07974.8 EMC78302.1 - 0.0084 16.2 12.2 0.0084 16.2 8.5 3.6 3 0 0 3 3 3 1 EGF-like domain OppC_N PF12911.2 EMC78302.1 - 0.023 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PMP1_2 PF08114.6 EMC78302.1 - 0.027 13.9 0.5 0.055 12.9 0.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family RSN1_TM PF13967.1 EMC78302.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport EphA2_TM PF14575.1 EMC78302.1 - 0.13 12.6 0.1 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycos_transf_4 PF00953.16 EMC78303.1 - 4.9e-35 120.6 16.4 4.9e-35 120.6 11.4 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 4 Porphobil_deam PF01379.15 EMC78304.1 - 7.6e-92 306.0 0.0 9.9e-92 305.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EMC78304.1 - 6.2e-19 67.8 0.0 8.3e-18 64.2 0.0 2.4 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CUE PF02845.11 EMC78304.1 - 0.0048 16.3 0.1 0.6 9.6 0.0 2.7 2 0 0 2 2 2 1 CUE domain CagA PF03507.8 EMC78304.1 - 0.054 13.3 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 CagA exotoxin VPS11_C PF12451.3 EMC78305.1 - 8.5e-20 70.3 2.3 9.3e-20 70.2 0.1 2.3 2 0 0 2 2 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 EMC78305.1 - 3.3e-17 62.4 13.8 9.3e-15 54.4 2.5 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EMC78305.1 - 2.5e-07 30.3 9.0 7.1e-07 28.9 6.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC78305.1 - 9.4e-07 28.7 7.5 2.1e-06 27.6 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC78305.1 - 9e-06 25.7 3.1 2.3e-05 24.4 2.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC78305.1 - 0.00012 21.6 8.0 0.00027 20.5 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC78305.1 - 0.0013 18.3 5.8 0.0025 17.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC78305.1 - 0.0019 17.9 8.6 0.0046 16.6 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 EMC78305.1 - 0.0083 15.7 1.5 0.055 13.1 0.0 3.1 3 1 0 3 3 3 1 TPR repeat zf-C3HC4_4 PF15227.1 EMC78305.1 - 0.02 14.7 8.2 0.056 13.3 5.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMC78305.1 - 0.044 13.6 2.2 0.15 11.9 1.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EMC78305.1 - 0.19 11.5 1.4 0.47 10.2 1.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DivIC PF04977.10 EMC78305.1 - 0.21 11.1 4.2 0.65 9.5 2.9 1.8 1 0 0 1 1 1 0 Septum formation initiator TPR_2 PF07719.12 EMC78305.1 - 0.29 11.1 2.3 14 5.9 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 EMC78305.1 - 0.68 9.7 12.0 7.2 6.4 3.4 4.0 3 0 0 3 3 3 0 Prefoldin subunit zf-Nse PF11789.3 EMC78305.1 - 0.8 9.2 5.3 2.3 7.8 3.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 EMC78305.1 - 4.3 7.4 6.5 12 5.9 4.5 1.8 1 0 0 1 1 1 0 RING-like domain DEAD PF00270.24 EMC78306.1 - 4.7e-39 133.5 0.4 4.7e-39 133.5 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC78306.1 - 3.4e-25 87.6 0.1 8.3e-25 86.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EMC78306.1 - 0.00065 18.8 0.1 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.18 EMC78306.1 - 0.012 14.4 0.1 0.022 13.5 0.0 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain 7tm_1 PF00001.16 EMC78307.1 - 1.2e-56 191.7 20.1 1.5e-56 191.4 14.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78307.1 - 5.3e-06 25.7 17.9 6.3e-06 25.5 12.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CRPA PF05745.6 EMC78307.1 - 0.24 11.1 3.9 0.36 10.6 0.2 2.4 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Yip1 PF04893.12 EMC78307.1 - 1.3 8.5 10.7 41 3.6 7.4 2.8 1 1 0 1 1 1 0 Yip1 domain DUF1772 PF08592.6 EMC78307.1 - 1.4 8.6 10.3 0.084 12.6 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF2304 PF10066.4 EMC78307.1 - 3.4 7.5 10.3 2.3 8.0 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF996 PF06195.8 EMC78307.1 - 3.7 7.5 9.4 5.9 6.8 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) CCDC84 PF14968.1 EMC78309.1 - 6.1e-44 150.9 2.1 6.5e-44 150.8 1.4 1.0 1 0 0 1 1 1 1 Coiled coil protein 84 Ribosomal_S25 PF03297.10 EMC78310.1 - 6.7e-41 138.5 0.3 7.4e-41 138.4 0.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.14 EMC78310.1 - 0.015 15.0 0.2 0.043 13.5 0.1 1.7 1 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.14 EMC78310.1 - 0.086 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.1 EMC78310.1 - 0.16 11.3 0.6 0.37 10.2 0.1 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Adap_comp_sub PF00928.16 EMC78311.1 - 4e-24 85.1 0.0 4.8e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family IFT46_B_C PF12317.3 EMC78312.1 - 2.8e-96 321.0 0.2 3.2e-96 320.8 0.2 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Sigma70_ner PF04546.8 EMC78312.1 - 1.3 8.6 3.8 0.64 9.5 1.0 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EMC78312.1 - 7.3 6.9 8.7 17 5.7 6.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain I-set PF07679.11 EMC78313.1 - 0.13 12.0 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain SET PF00856.23 EMC78314.1 - 1.9e-23 83.5 0.7 1.9e-23 83.5 0.5 4.9 5 0 0 5 5 5 1 SET domain FYRC PF05965.9 EMC78314.1 - 4.3e-23 80.9 0.0 1.1e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 EMC78314.1 - 2.4e-16 58.9 0.2 4.8e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.1 EMC78314.1 - 9.9e-15 54.4 11.0 9.9e-15 54.4 7.6 5.6 4 1 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.24 EMC78314.1 - 2.9e-14 52.4 53.6 3.3e-08 33.1 8.4 5.7 5 1 2 7 7 7 3 PHD-finger zf-CXXC PF02008.15 EMC78314.1 - 2e-13 49.8 24.3 2e-13 49.8 16.9 5.4 5 0 0 5 5 5 1 CXXC zinc finger domain zf-HC5HC2H_2 PF13832.1 EMC78314.1 - 1.7e-08 34.4 9.9 1.7e-08 34.4 6.9 5.1 4 1 1 5 5 5 1 PHD-zinc-finger like domain PHD_2 PF13831.1 EMC78314.1 - 1.1e-05 24.5 25.8 0.0014 17.8 2.0 4.2 3 0 0 3 3 3 2 PHD-finger Ufd2P_core PF10408.4 EMC78315.1 - 2.8e-175 584.1 4.7 3.9e-175 583.6 3.3 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EMC78315.1 - 1.7e-32 111.1 1.1 4.7e-32 109.7 0.4 2.1 2 0 0 2 2 2 1 U-box domain IRK PF01007.15 EMC78316.1 - 2.3e-120 401.4 0.8 2.8e-120 401.1 0.6 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC78316.1 - 0.00062 19.4 2.0 0.00075 19.1 0.7 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 EMC78316.1 - 0.033 13.4 4.1 0.052 12.7 2.8 1.2 1 0 0 1 1 1 0 Ion transport protein Neur_chan_LBD PF02931.18 EMC78317.1 - 1e-51 175.1 1.5 1.4e-51 174.7 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC78317.1 - 3.5e-25 89.2 0.0 4.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region NNMT_PNMT_TEMT PF01234.12 EMC78319.1 - 8.9e-79 264.0 0.0 9.7e-79 263.9 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.1 EMC78319.1 - 2e-07 30.8 0.0 2.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC78319.1 - 3.9e-07 30.6 0.0 6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC78319.1 - 1.6e-06 28.5 0.0 7.2e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC78319.1 - 3.5e-05 24.0 0.0 0.00011 22.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC78319.1 - 0.0036 17.7 0.0 0.028 14.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC78319.1 - 0.0065 16.5 0.1 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC78319.1 - 0.03 13.9 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain RNase_T PF00929.19 EMC78320.1 - 2.8e-20 73.2 0.0 3.3e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease I-set PF07679.11 EMC78321.1 - 3.4e-25 87.7 0.1 7.2e-11 41.7 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78321.1 - 6e-25 87.1 0.7 1e-10 41.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC78321.1 - 5.7e-19 68.1 2.3 2e-07 30.8 0.1 4.3 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC78321.1 - 5e-17 62.1 8.9 6.5e-09 36.1 0.0 3.9 4 0 0 4 4 3 3 Immunoglobulin domain ig PF00047.20 EMC78321.1 - 8.5e-17 61.0 2.3 6.4e-05 23.0 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.7 EMC78321.1 - 3.2e-12 46.1 2.2 1.1e-10 41.2 0.0 3.2 4 0 0 4 4 3 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC78321.1 - 0.00023 19.5 0.2 0.3 9.2 0.0 3.0 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E C2-set PF05790.10 EMC78321.1 - 0.0049 16.8 0.0 28 4.7 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain OppC_N PF12911.2 EMC78321.1 - 0.033 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Syndecan PF01034.15 EMC78321.1 - 0.049 13.2 0.1 0.3 10.7 0.1 2.0 2 0 0 2 2 2 0 Syndecan domain Rubella_E2 PF05749.6 EMC78321.1 - 0.049 12.8 0.3 0.092 11.9 0.2 1.5 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DUF3439 PF11921.3 EMC78321.1 - 1.1 8.9 10.5 2.6 7.8 7.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Bud13 PF09736.4 EMC78322.1 - 1.1e-45 155.4 12.9 3.5e-45 153.8 8.9 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex zf-ZPR1 PF03367.8 EMC78323.1 - 2.9e-96 319.1 0.0 4.3e-51 172.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain PAS_4 PF08448.5 EMC78325.1 - 0.007 16.3 0.0 0.39 10.7 0.0 2.0 1 1 1 2 2 2 2 PAS fold Peptidase_S8 PF00082.17 EMC78327.1 - 9.8e-49 165.9 0.8 1.2e-48 165.7 0.6 1.1 1 0 0 1 1 1 1 Subtilase family WW PF00397.21 EMC78328.1 - 7e-07 28.9 0.2 1.1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 WW domain ATP1G1_PLM_MAT8 PF02038.11 EMC78329.1 - 1.7e-21 74.9 0.2 2.3e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family ATP1G1_PLM_MAT8 PF02038.11 EMC78331.1 - 4.9e-28 95.8 0.0 7.5e-28 95.2 0.0 1.3 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family DUF2567 PF10821.3 EMC78331.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DUF2367 PF10164.4 EMC78331.1 - 0.11 12.3 0.2 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Trypsin PF00089.21 EMC78332.1 - 4.1e-72 242.3 3.8 3.5e-71 239.2 0.5 2.0 2 0 0 2 2 2 1 Trypsin SRCR_2 PF15494.1 EMC78332.1 - 1.6e-20 73.1 4.6 3.5e-20 72.0 3.2 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 EMC78332.1 - 4.5e-08 32.7 0.4 7.7e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Hepsin-SRCR PF09272.5 EMC78332.1 - 1.5e-05 25.1 1.3 6.6e-05 23.0 0.9 2.0 1 1 0 1 1 1 1 Hepsin, SRCR DUF316 PF03761.10 EMC78332.1 - 1.7e-05 24.3 0.1 0.14 11.4 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF316) SRCR PF00530.13 EMC78332.1 - 1.9e-05 24.8 1.4 1.9e-05 24.8 1.0 2.3 2 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.13 EMC78332.1 - 0.0019 18.0 2.8 0.0071 16.2 1.9 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.1 EMC78332.1 - 0.0074 16.2 0.0 0.028 14.4 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EMC78333.1 - 9.6e-70 234.5 0.3 1.2e-69 234.3 0.2 1.1 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 EMC78333.1 - 8.6e-18 64.3 0.0 1.8e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.1 EMC78333.1 - 7.1e-07 29.2 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 EMC78333.1 - 0.00032 20.0 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Hepsin-SRCR PF09272.5 EMC78333.1 - 0.0004 20.5 1.2 0.0024 18.0 0.8 2.2 1 1 0 1 1 1 1 Hepsin, SRCR SRCR PF00530.13 EMC78333.1 - 0.0028 17.9 0.0 0.008 16.4 0.0 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain V-set PF07686.12 EMC78334.1 - 5.7e-09 35.8 0.1 1.1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC78334.1 - 5.2e-07 29.7 0.1 9.3e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC78334.1 - 5.4e-07 29.3 0.1 2.5e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC78334.1 - 1.8e-06 27.9 0.7 1.3e-05 25.2 0.5 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 EMC78334.1 - 0.00076 19.2 1.3 0.0014 18.4 0.9 1.4 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Ig_3 PF13927.1 EMC78334.1 - 0.0014 19.0 1.3 0.0044 17.4 0.9 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Tmemb_9 PF05434.6 EMC78334.1 - 0.018 14.8 0.1 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 TMEM9 Herpes_gE PF02480.11 EMC78334.1 - 0.021 13.0 1.1 0.033 12.4 0.1 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Glycophorin_A PF01102.13 EMC78334.1 - 0.024 14.3 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A V-set PF07686.12 EMC78335.1 - 3.9e-18 65.4 0.4 6e-18 64.8 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC78335.1 - 2e-06 27.8 0.4 3.2e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC78335.1 - 2.5e-06 27.2 0.0 1.1e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain DUF1191 PF06697.7 EMC78335.1 - 7.6e-05 21.6 0.0 0.0001 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) ig PF00047.20 EMC78335.1 - 0.00011 22.2 4.2 0.0011 19.0 2.9 2.3 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.1 EMC78335.1 - 0.0023 18.2 0.0 0.0042 17.4 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EMC78335.1 - 0.0041 15.4 0.4 0.4 8.9 0.2 2.2 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E Ig_3 PF13927.1 EMC78335.1 - 0.014 15.8 5.4 0.058 13.9 3.7 2.0 1 1 0 1 1 1 0 Immunoglobulin domain FAM176 PF14851.1 EMC78335.1 - 0.018 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Adeno_E3_CR2 PF02439.10 EMC78335.1 - 0.057 12.9 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CcmH PF03918.9 EMC78335.1 - 0.063 12.2 0.3 0.46 9.4 0.0 2.2 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Mid2 PF04478.7 EMC78335.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EMC78335.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family V-set PF07686.12 EMC78336.1 - 4.5e-09 36.1 0.0 8.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.11 EMC78336.1 - 0.00028 19.2 0.1 0.12 10.5 0.0 2.1 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E ig PF00047.20 EMC78336.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain V-set PF07686.12 EMC78338.1 - 5.1e-15 55.3 0.0 7.5e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC78338.1 - 0.0037 17.3 0.0 0.0081 16.2 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC78338.1 - 0.013 15.9 1.0 0.7 10.4 0.7 2.4 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 EMC78338.1 - 0.016 15.0 0.0 0.056 13.3 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.20 EMC78338.1 - 0.046 13.8 0.2 0.14 12.3 0.1 1.8 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC78339.1 - 2.3e-20 72.6 0.1 3.6e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC78339.1 - 8.4e-06 25.5 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78339.1 - 2e-05 24.6 0.1 4.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC78339.1 - 0.00012 22.0 1.0 0.00083 19.4 0.7 2.3 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.1 EMC78339.1 - 0.0052 17.1 0.2 0.0093 16.3 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EMC78339.1 - 0.012 15.3 0.8 0.014 15.0 0.1 1.5 2 0 0 2 2 2 0 TMEM154 protein family DUF1510 PF07423.6 EMC78339.1 - 0.032 13.6 0.3 0.043 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TMEM51 PF15345.1 EMC78339.1 - 0.044 13.4 0.1 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ig_3 PF13927.1 EMC78339.1 - 0.044 14.3 3.8 0.71 10.4 2.6 2.3 1 1 0 1 1 1 0 Immunoglobulin domain Protocadherin PF08374.6 EMC78339.1 - 0.049 13.2 0.6 0.089 12.4 0.4 1.4 1 0 0 1 1 1 0 Protocadherin MLANA PF14991.1 EMC78339.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DUF3481 PF11980.3 EMC78339.1 - 0.064 13.0 0.3 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) DAP10 PF07213.6 EMC78339.1 - 0.077 12.7 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein DUF3169 PF11368.3 EMC78339.1 - 0.09 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Vpu PF00558.14 EMC78339.1 - 2.3 7.8 5.8 0.18 11.3 0.6 1.7 2 0 0 2 2 2 0 Vpu protein ITAM PF02189.10 EMC78340.1 - 0.0014 18.7 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif CHB_HEX_C PF03174.8 EMC78340.1 - 0.057 13.2 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain ITAM PF02189.10 EMC78341.1 - 1.1e-05 25.3 0.2 2.4e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif Ig_2 PF13895.1 EMC78341.1 - 0.0064 16.5 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain DAP10 PF07213.6 EMC78341.1 - 0.022 14.4 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 DAP10 membrane protein PMT PF02366.13 EMC78341.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Zw10 PF06248.8 EMC78342.1 - 1.9e-209 696.7 13.1 2.4e-209 696.4 9.1 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF77 PF01910.12 EMC78342.1 - 0.11 12.1 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF77 TPX2 PF06886.6 EMC78342.1 - 0.17 11.9 1.6 0.72 9.9 1.1 2.1 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) 7tm_1 PF00001.16 EMC78343.1 - 1.6e-102 342.0 10.9 2.3e-102 341.5 7.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78343.1 - 4.4e-18 65.3 22.2 1.8e-13 50.2 10.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC78343.1 - 1.1e-05 24.7 25.3 0.0014 17.8 12.1 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Rifin_STEVOR PF02009.11 EMC78343.1 - 0.0075 15.9 0.6 0.018 14.7 0.4 1.6 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 EMC78343.1 - 0.051 13.2 3.4 0.067 12.9 0.0 2.7 4 0 0 4 4 4 0 TMEM154 protein family CcmH PF03918.9 EMC78343.1 - 0.054 12.4 0.1 1.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Ank PF00023.25 EMC78344.1 - 4e-108 348.2 9.1 8.6e-10 37.9 0.0 12.0 12 0 0 12 12 12 12 Ankyrin repeat Ank_2 PF12796.2 EMC78344.1 - 1.3e-90 297.8 10.8 1.3e-17 63.9 0.1 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMC78344.1 - 1.5e-74 238.4 13.5 4.7e-06 26.3 0.0 12.0 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 EMC78344.1 - 4.9e-71 233.9 11.0 1e-10 41.7 0.0 9.2 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC78344.1 - 6.4e-56 185.1 12.5 5.1e-09 36.0 0.0 8.3 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Pkinase PF00069.20 EMC78345.1 - 2.3e-49 167.9 0.0 3e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78345.1 - 1.1e-46 159.0 0.0 1.3e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC78345.1 - 0.0095 15.6 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family I-set PF07679.11 EMC78347.1 - 1.2e-77 255.8 5.8 4.8e-19 67.9 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78347.1 - 2.4e-50 168.5 0.6 3.6e-11 43.0 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 EMC78347.1 - 1.6e-37 127.8 7.4 1.6e-07 31.7 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 EMC78347.1 - 5.1e-36 122.6 2.4 3.4e-07 30.2 0.1 6.0 6 0 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.16 EMC78347.1 - 2.3e-25 88.5 0.3 4.7e-13 49.0 0.0 3.1 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.12 EMC78347.1 - 4.9e-23 81.1 2.8 0.0012 18.7 0.0 6.2 5 0 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC78347.1 - 4.2e-12 45.8 4.5 0.013 15.4 0.0 5.5 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC78347.1 - 1.9e-08 34.1 3.4 0.00034 20.5 0.0 4.6 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.3 EMC78347.1 - 0.0016 18.3 0.7 0.98 9.3 0.0 4.0 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 BiPBP_C PF06832.7 EMC78347.1 - 0.0031 17.4 0.0 2.3 8.2 0.0 3.3 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family PTPS PF01242.14 EMC78349.1 - 5.4e-32 110.0 0.0 6.7e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RPE65 PF03055.10 EMC78350.1 - 1.9e-132 442.2 0.0 2.4e-132 441.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein IL1 PF00340.14 EMC78351.1 - 9.2e-32 109.0 0.8 1.5e-31 108.3 0.5 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 CybS PF05328.7 EMC78352.1 - 2.4e-36 124.2 1.2 2.6e-36 124.1 0.8 1.0 1 0 0 1 1 1 1 CybS Subtilosin_A PF11420.3 EMC78352.1 - 0.058 13.4 0.4 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Bacteriocin subtilosin A CDC27 PF09507.5 EMC78353.1 - 0.41 9.8 52.5 0.52 9.4 36.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.4 EMC78353.1 - 3.8 5.6 33.4 4.6 5.3 23.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 2-oxoacid_dh PF00198.18 EMC78354.1 - 6e-82 274.3 0.1 7.8e-82 273.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMC78354.1 - 3.2e-33 113.2 0.4 1.6e-15 56.4 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.12 EMC78354.1 - 6.9e-20 70.3 0.6 2.1e-19 68.8 0.4 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EMC78354.1 - 4.1e-05 23.1 0.0 0.056 13.1 0.0 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 EMC78354.1 - 0.012 14.8 0.1 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein DUF2118 PF09891.4 EMC78354.1 - 0.063 12.9 0.0 11 5.7 0.0 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 EMC78354.1 - 0.097 11.8 0.1 2.6 7.1 0.0 2.4 2 1 1 3 3 3 0 HlyD family secretion protein QRPTase_N PF02749.11 EMC78354.1 - 0.12 12.2 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Pou PF00157.12 EMC78355.1 - 3.1e-39 132.4 0.1 6e-39 131.5 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 EMC78355.1 - 1.5e-18 66.1 3.3 3.9e-18 64.8 2.3 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC78355.1 - 0.0064 16.1 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.17 EMC78355.1 - 0.12 12.2 0.2 1.1 9.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix OAF PF14941.1 EMC78356.1 - 3.2e-112 373.5 5.3 3.6e-112 373.3 3.7 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first BRICHOS PF04089.9 EMC78356.1 - 0.027 14.3 0.2 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 BRICHOS domain zf-B_box PF00643.19 EMC78357.1 - 7.1e-11 41.8 6.1 7.1e-11 41.8 4.2 2.4 2 1 0 2 2 2 2 B-box zinc finger zf-RING_5 PF14634.1 EMC78357.1 - 0.053 13.2 2.3 0.053 13.2 1.6 2.6 3 0 0 3 3 3 0 zinc-RING finger domain IBR PF01485.16 EMC78357.1 - 3.2 7.6 13.3 1.7 8.5 1.4 2.3 2 0 0 2 2 2 0 IBR domain C2-set_2 PF08205.7 EMC78358.1 - 7.7e-19 67.3 0.5 1.4e-17 63.3 0.0 2.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 EMC78358.1 - 2.4e-16 59.6 2.0 8.1e-07 29.0 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 EMC78358.1 - 1e-15 57.5 2.1 6e-08 32.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC78358.1 - 1.6e-12 47.3 0.4 2.6e-11 43.3 0.0 2.9 4 0 0 4 4 4 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC78358.1 - 4.6e-11 43.0 7.2 0.00089 19.7 0.2 3.9 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 EMC78358.1 - 4.2e-07 29.7 0.1 0.0016 18.2 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Herpes_gE PF02480.11 EMC78358.1 - 3.4e-06 25.6 0.0 0.039 12.2 0.0 2.2 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EMC78358.1 - 0.0064 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EMC78358.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain V-set PF07686.12 EMC78359.1 - 3.8e-05 23.5 0.8 6.2e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC78359.1 - 0.00026 21.0 1.0 0.00054 20.0 0.3 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 EMC78359.1 - 0.00086 19.3 0.8 0.0012 18.9 0.5 1.2 1 0 0 1 1 1 1 Immunoglobulin domain RPA_C PF08784.6 EMC78359.1 - 0.0077 16.6 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Replication protein A C terminal NEAT PF05031.7 EMC78359.1 - 0.0078 16.2 0.1 0.018 15.0 0.0 1.5 2 0 0 2 2 2 1 Iron Transport-associated domain I-set PF07679.11 EMC78359.1 - 0.014 15.2 0.4 0.025 14.4 0.3 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain UCH PF00443.24 EMC78360.1 - 1e-77 260.8 1.6 1.3e-77 260.5 1.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC78360.1 - 5.2e-26 91.7 3.2 6.3e-26 91.4 2.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EMC78360.1 - 0.23 10.7 7.4 8.9 5.4 0.0 3.2 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CUB PF00431.15 EMC78362.1 - 2.7e-24 85.3 0.0 4.1e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 CUB domain Fz PF01392.17 EMC78362.1 - 1.4e-20 73.7 1.1 1.4e-20 73.7 0.8 1.7 2 0 0 2 2 2 1 Fz domain Ldl_recept_a PF00057.13 EMC78362.1 - 1.3e-09 37.8 8.7 1.3e-09 37.8 6.0 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Carb_bind PF10645.4 EMC78362.1 - 3 7.7 7.1 1.6 8.5 3.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding C1q PF00386.16 EMC78363.1 - 9e-36 122.6 0.0 1.1e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC78363.1 - 1.8e-10 40.2 33.2 5e-08 32.3 23.0 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Brevenin PF03032.10 EMC78363.1 - 0.027 14.3 0.6 0.041 13.7 0.4 1.3 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family zf-C3HC4_3 PF13920.1 EMC78364.1 - 4.4e-15 55.0 11.4 5.1e-15 54.8 7.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC78364.1 - 7.5e-08 32.0 12.7 9.6e-08 31.7 8.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC78364.1 - 1.3e-07 31.5 12.5 1.9e-07 31.0 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC78364.1 - 6.8e-05 22.4 13.0 9.2e-05 22.0 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC78364.1 - 0.0011 18.5 13.6 0.0027 17.3 9.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC78364.1 - 0.042 13.6 6.8 0.068 13.0 4.7 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CABIT PF12736.2 EMC78364.1 - 0.16 10.9 0.8 0.17 10.8 0.5 1.1 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, Prok-RING_4 PF14447.1 EMC78364.1 - 0.34 10.4 10.2 2.3 7.8 7.1 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EMC78364.1 - 1.1 8.7 11.9 2.3 7.7 8.2 1.6 1 1 0 1 1 1 0 P-11 zinc finger Spt4 PF06093.8 EMC78364.1 - 3.3 7.6 8.8 1 9.3 2.6 2.0 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger dCMP_cyt_deam_1 PF00383.17 EMC78364.1 - 4.3 7.0 7.3 4.6 6.9 2.0 2.1 1 1 1 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Ig_2 PF13895.1 EMC78366.1 - 5.2e-28 96.9 0.2 6.9e-09 35.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 EMC78366.1 - 2.8e-23 81.5 0.1 1e-21 76.5 0.1 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 EMC78366.1 - 9.5e-19 67.6 1.1 6.6e-05 23.3 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC78366.1 - 1.3e-16 60.4 1.9 0.00012 22.1 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 EMC78366.1 - 5.1e-16 58.3 0.1 1.6e-06 27.8 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain V-set PF07686.12 EMC78366.1 - 2.4e-06 27.3 3.9 0.031 14.1 0.0 5.0 3 3 1 4 4 4 1 Immunoglobulin V-set domain C1-set PF07654.10 EMC78366.1 - 1.1e-05 25.3 1.1 0.00025 20.9 0.1 3.1 3 1 0 3 3 3 1 Immunoglobulin C1-set domain TOBE_2 PF08402.5 EMC78366.1 - 0.09 12.7 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 TOBE domain PDZ PF00595.19 EMC78367.1 - 2.4e-38 130.1 0.0 1.8e-11 44.0 0.0 3.1 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC78367.1 - 1.3e-21 76.2 0.0 4.2e-07 29.7 0.0 3.1 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.1 EMC78367.1 - 5.8e-07 29.2 0.2 0.18 11.5 0.0 3.2 3 0 0 3 3 3 3 Tricorn protease PDZ domain ABC2_membrane PF01061.19 EMC78369.1 - 1.9e-24 86.0 25.5 2e-19 69.5 9.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMC78369.1 - 3.4e-09 37.1 0.0 5.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC78369.1 - 3.3e-06 27.2 0.0 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMC78369.1 - 3.6e-05 22.9 10.2 3.6e-05 22.9 7.1 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.14 EMC78369.1 - 0.00022 20.5 0.0 0.00032 20.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.2 EMC78369.1 - 0.16 10.8 13.1 0.019 13.8 3.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2157 PF09925.4 EMC78369.1 - 0.17 11.5 3.9 0.42 10.2 2.7 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) zf-C2H2 PF00096.21 EMC78370.1 - 3.3e-18 64.8 80.1 4.5e-05 23.5 3.9 9.3 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC78370.1 - 1.3e-17 63.1 69.0 1.7e-06 28.0 2.3 9.8 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC78370.1 - 5.7e-13 48.2 74.8 0.00034 20.7 2.7 9.5 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC78370.1 - 2.8e-05 24.0 43.7 0.0022 18.0 0.6 7.3 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC78370.1 - 3.2e-05 23.9 33.9 0.15 12.2 0.0 6.5 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC78370.1 - 0.00066 19.4 1.4 0.00066 19.4 1.0 7.8 8 0 0 8 8 8 2 C2H2-type zinc finger zf-Di19 PF05605.7 EMC78370.1 - 0.0016 18.4 6.9 0.0016 18.4 4.8 6.6 5 1 1 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EMC78370.1 - 0.006 16.7 56.3 0.07 13.3 1.2 8.0 8 0 0 8 8 8 4 C2H2-type zinc-finger domain Nudix_N_2 PF14803.1 EMC78370.1 - 0.021 14.5 8.1 0.25 11.0 0.7 4.3 3 0 0 3 3 3 0 Nudix N-terminal zf-C2HC_2 PF13913.1 EMC78370.1 - 0.022 14.4 0.8 0.022 14.4 0.6 5.8 7 0 0 7 7 6 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EMC78370.1 - 0.55 10.3 42.7 0.24 11.5 3.7 6.3 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Ank_2 PF12796.2 EMC78373.1 - 3.4e-42 142.6 13.1 3.3e-13 49.7 0.3 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC78373.1 - 2.5e-33 112.2 2.0 1.6e-07 30.7 0.1 6.9 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EMC78373.1 - 5.9e-26 89.9 3.6 1.5e-12 47.2 0.0 5.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC78373.1 - 3.4e-25 87.9 3.2 2.2e-07 31.1 0.0 5.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) PD-C2-AF1 PF09310.5 EMC78373.1 - 3.5e-24 85.3 0.3 5.5e-24 84.7 0.2 1.3 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 Ank_3 PF13606.1 EMC78373.1 - 5.2e-21 72.6 3.4 4.9e-05 23.1 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat BTG PF07742.7 EMC78374.1 - 2.4e-45 152.8 0.1 3.4e-45 152.4 0.1 1.2 1 0 0 1 1 1 1 BTG family Lectin_C PF00059.16 EMC78376.1 - 1.8e-16 60.6 0.4 5.3e-16 59.1 0.2 1.9 1 0 0 1 1 1 1 Lectin C-type domain DUF912 PF06024.7 EMC78376.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 EMC78377.1 - 1.4e-69 234.1 0.0 2.5e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78377.1 - 1.1e-35 122.9 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC78377.1 - 6.5e-08 31.8 0.0 1.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC78377.1 - 0.016 14.2 0.1 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2431 PF10354.4 EMC78378.1 - 4.8e-36 124.2 0.0 5.9e-25 88.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) FDX-ACB PF03147.9 EMC78378.1 - 4.6e-17 61.9 0.0 8.1e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Methyltransf_26 PF13659.1 EMC78378.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_2d PF01409.15 EMC78378.1 - 0.12 11.5 0.0 0.36 9.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF883 PF05957.8 EMC78378.1 - 1.4 9.3 3.3 1.6 9.1 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HSP20 PF00011.16 EMC78379.1 - 3.2e-28 97.5 0.1 3.9e-28 97.2 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 EMC78379.1 - 1.5e-26 92.3 3.3 2.5e-26 91.6 2.3 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.16 EMC78380.1 - 5.6e-20 71.1 0.0 8.8e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 EMC78380.1 - 6.9e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal DAO PF01266.19 EMC78381.1 - 5.6e-21 74.8 0.1 6.3e-21 74.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase SH3_2 PF07653.12 EMC78382.1 - 7.1e-13 47.8 0.0 9e-13 47.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC78382.1 - 1.2e-07 31.0 0.2 2.4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC78382.1 - 1.3e-07 31.0 0.1 2.1e-07 30.4 0.1 1.4 1 1 0 1 1 1 1 Variant SH3 domain Guanylate_kin PF00625.16 EMC78383.1 - 4e-40 137.2 0.0 4.5e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF258 PF03193.11 EMC78383.1 - 0.0081 15.3 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FYRN PF05964.9 EMC78384.1 - 0.013 14.8 6.5 5.3 6.5 0.2 3.8 2 1 1 3 3 3 0 F/Y-rich N-terminus DUF4087 PF13316.1 EMC78384.1 - 0.24 11.6 26.7 1.4 9.1 2.6 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF4087) Collagen PF01391.13 EMC78386.1 - 9.2e-14 50.7 32.0 1.3e-11 43.8 22.2 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) COLFI PF01410.13 EMC78387.1 - 7.6e-28 97.3 0.0 8.2e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Homeobox PF00046.24 EMC78388.1 - 1.4e-21 75.8 3.6 2.4e-21 75.0 2.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC78388.1 - 0.0041 16.7 0.1 0.0091 15.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC78388.1 - 0.011 14.8 0.2 0.023 13.7 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.1 EMC78388.1 - 0.19 11.9 0.4 1.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HisG_C PF08029.6 EMC78389.1 - 0.062 13.2 10.0 1.9e+02 2.1 0.0 6.9 1 1 13 14 14 14 0 HisG, C-terminal domain DUF3385 PF11865.3 EMC78389.1 - 0.1 12.5 27.9 30 4.5 1.0 6.9 1 1 9 10 10 10 0 Domain of unknown function (DUF3385) MOZ_SAS PF01853.13 EMC78391.1 - 2.9e-89 297.2 2.4 4.5e-89 296.7 1.7 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-C2HC PF01530.13 EMC78391.1 - 1.8e-14 53.1 4.5 1.8e-14 53.1 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C2HC type Palm_thioest PF02089.10 EMC78391.1 - 0.027 13.4 0.1 6 5.7 0.0 2.4 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Acetyltransf_7 PF13508.1 EMC78391.1 - 0.039 14.1 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-met PF12874.2 EMC78391.1 - 0.047 13.9 0.4 0.15 12.3 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Methyltransf_23 PF13489.1 EMC78392.1 - 5.9e-15 55.3 0.0 8.2e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC78392.1 - 2.3e-14 53.6 0.0 4.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC78392.1 - 1.7e-13 50.8 0.0 3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC78392.1 - 1.8e-10 41.0 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC78392.1 - 2.9e-10 39.9 0.0 4.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC78392.1 - 2.8e-09 37.5 0.0 4.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC78392.1 - 1.5e-06 27.4 0.0 6.8e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMC78392.1 - 1.4e-05 25.0 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC78392.1 - 0.0009 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 EMC78392.1 - 0.004 16.8 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase CheR PF01739.13 EMC78392.1 - 0.018 14.3 0.1 0.36 10.1 0.0 2.1 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF3419 PF11899.3 EMC78392.1 - 0.023 13.4 0.0 0.05 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 EMC78392.1 - 0.06 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 EMC78392.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Peptidase_M2 PF01401.13 EMC78393.1 - 0 2138.1 20.8 0 1077.3 4.3 2.0 2 0 0 2 2 2 2 Angiotensin-converting enzyme Ion_trans PF00520.26 EMC78394.1 - 1.9e-19 69.7 5.2 3.4e-19 68.9 3.6 1.4 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.1 EMC78394.1 - 3.8e-18 65.7 0.0 7.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.24 EMC78394.1 - 2.9e-13 49.4 0.0 5.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 EMC78394.1 - 1.1e-11 44.2 0.1 1.1e-11 44.2 0.1 2.0 3 0 0 3 3 1 1 Ion channel PAS PF00989.19 EMC78394.1 - 5.1e-08 32.6 0.0 2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 EMC78394.1 - 0.00028 20.9 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMC78394.1 - 0.00063 19.7 0.0 0.021 14.8 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 EMC78394.1 - 0.0016 18.2 0.0 0.0054 16.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain Ion_trans_N PF08412.5 EMC78394.1 - 0.0058 15.9 0.2 0.017 14.4 0.2 1.8 1 0 0 1 1 1 1 Ion transport protein N-terminal DegS PF05384.6 EMC78394.1 - 0.047 12.8 0.1 0.95 8.6 0.0 2.6 3 0 0 3 3 3 0 Sensor protein DegS PAN_3 PF08277.7 EMC78394.1 - 4.2 7.0 6.5 0.92 9.1 1.1 2.4 3 0 0 3 3 3 0 PAN-like domain WD40 PF00400.27 EMC78395.1 - 4.6e-17 61.1 8.8 6.2e-06 25.8 1.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.20 EMC78396.1 - 1.8e-67 227.2 0.0 2.5e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78396.1 - 4.6e-42 143.8 0.0 6.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 EMC78396.1 - 3.9e-12 45.6 0.1 9.2e-12 44.4 0.1 1.7 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 EMC78396.1 - 6.7e-06 25.2 0.0 0.00022 20.2 0.0 2.4 1 1 1 2 2 2 1 Kinase-like LIM PF00412.17 EMC78397.1 - 3.9e-12 46.0 10.6 5.1e-12 45.6 7.4 1.2 1 0 0 1 1 1 1 LIM domain DZR PF12773.2 EMC78397.1 - 0.045 13.5 3.9 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.1 EMC78399.1 - 2.9e-09 36.8 12.0 5.7e-09 35.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC78399.1 - 4.4e-09 35.8 9.3 8e-09 35.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EMC78399.1 - 6.2e-09 35.3 2.3 6.2e-09 35.3 1.6 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EMC78399.1 - 1.8e-07 30.8 10.5 3.2e-07 30.0 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC78399.1 - 3.6e-06 26.5 11.2 8.3e-06 25.3 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC78399.1 - 5.3e-06 26.0 12.7 1e-05 25.1 8.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC78399.1 - 0.0012 18.6 9.6 0.0012 18.6 6.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC78399.1 - 0.0019 17.8 3.8 0.006 16.2 2.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EMC78399.1 - 0.0045 16.4 5.3 0.0096 15.4 3.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 EMC78399.1 - 0.11 11.9 7.6 0.21 11.1 5.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 EMC78399.1 - 0.46 10.6 10.6 0.36 10.9 5.5 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger Pkinase PF00069.20 EMC78400.1 - 1.5e-33 116.0 0.0 2.4e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78400.1 - 2.1e-23 82.7 0.0 3.5e-22 78.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC78400.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1682 PF07946.9 EMC78401.1 - 6.5e-106 353.8 7.4 8.9e-106 353.3 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Guanylate_kin PF00625.16 EMC78402.1 - 1.2e-40 138.8 0.4 1.9e-40 138.2 0.3 1.3 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.11 EMC78402.1 - 2.6e-24 84.6 4.3 7.3e-13 47.9 0.4 2.6 2 0 0 2 2 2 2 L27 domain PDZ PF00595.19 EMC78402.1 - 1.2e-12 47.8 0.8 2.6e-12 46.7 0.5 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC78402.1 - 1.4e-05 24.9 0.1 5.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 PDZ domain SH3_1 PF00018.23 EMC78402.1 - 0.0026 17.1 0.0 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF1409 PF07197.7 EMC78402.1 - 1.9 8.6 5.2 0.33 11.0 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) Ras PF00071.17 EMC78403.1 - 9e-49 164.9 0.0 1.1e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EMC78403.1 - 2.1e-12 46.6 0.0 2.6e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMC78403.1 - 1.2e-11 45.1 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC78403.1 - 0.0007 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC78403.1 - 0.047 12.8 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DSPc PF00782.15 EMC78404.1 - 1.2e-33 115.4 0.0 1.5e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC78404.1 - 7.6e-06 25.4 0.0 8.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EMC78404.1 - 0.00074 18.5 0.0 0.00074 18.5 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 EMC78404.1 - 0.0027 17.7 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF442 PF04273.8 EMC78404.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.7 1 1 0 1 1 1 1 Putative phosphatase (DUF442) Sclerostin PF05463.6 EMC78405.1 - 2.6e-76 255.5 4.5 2.8e-76 255.4 3.1 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.10 EMC78405.1 - 4.4e-09 35.7 1.0 7.3e-09 35.0 0.7 1.3 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 EMC78405.1 - 1.3e-06 28.4 2.1 2.4e-06 27.5 1.4 1.5 1 0 0 1 1 1 1 Cystine-knot domain Homeobox PF00046.24 EMC78406.1 - 3.1e-23 81.1 7.7 5.2e-23 80.4 5.4 1.4 1 0 0 1 1 1 1 Homeobox domain PP_M1 PF03012.9 EMC78406.1 - 0.19 11.0 3.8 0.27 10.5 2.6 1.2 1 0 0 1 1 1 0 Phosphoprotein ETS_PEA3_N PF04621.8 EMC78407.1 - 3.3e-72 243.5 18.4 5.3e-71 239.6 12.7 2.2 1 1 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.17 EMC78407.1 - 6.3e-38 128.7 0.2 1e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Ets-domain CRISPR_assoc PF08798.6 EMC78407.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein OB_NTP_bind PF07717.11 EMC78408.1 - 4.7e-30 103.7 0.0 1e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC78408.1 - 2.3e-29 101.4 0.2 9.1e-29 99.4 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) S1 PF00575.18 EMC78408.1 - 1.5e-13 50.6 0.1 2.9e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 EMC78408.1 - 7.1e-12 45.0 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC78408.1 - 6.2e-07 29.0 0.4 3.2e-06 26.7 0.3 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1777 PF08648.7 EMC78408.1 - 5.6e-05 22.9 40.7 0.00016 21.4 28.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) AAA_22 PF13401.1 EMC78408.1 - 0.00015 21.9 0.3 0.00056 20.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EMC78408.1 - 0.00019 20.4 0.1 0.00046 19.1 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EMC78408.1 - 0.00056 19.6 0.0 0.0017 18.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Flavi_DEAD PF07652.9 EMC78408.1 - 0.016 14.9 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Sigma54_activ_2 PF14532.1 EMC78408.1 - 0.034 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain PhoH PF02562.11 EMC78408.1 - 0.08 12.1 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 EMC78408.1 - 0.094 13.0 1.8 0.68 10.2 0.1 3.1 3 1 1 4 4 4 0 ABC transporter DUF1356 PF07092.7 EMC78409.1 - 1e-87 293.2 0.8 1.1e-87 293.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) ADH_zinc_N_2 PF13602.1 EMC78410.1 - 1.3e-19 71.3 0.0 2.3e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMC78410.1 - 3.4e-17 62.2 0.0 7.1e-17 61.1 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NID PF07292.8 EMC78413.1 - 2.7e-39 133.0 0.1 3.7e-23 81.3 0.1 2.6 2 1 0 2 2 2 2 Nmi/IFP 35 domain (NID) Ribosomal_L27e PF01777.13 EMC78414.1 - 8.3e-39 131.6 7.7 9.7e-39 131.3 5.3 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family RUN PF02759.14 EMC78415.1 - 2.7e-32 111.3 0.1 4.8e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 RUN domain CS PF04969.11 EMC78416.1 - 6e-09 36.3 0.0 8.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 CS domain Nod_GRP PF07806.6 EMC78416.1 - 0.02 14.5 2.2 0.037 13.6 1.5 1.4 1 0 0 1 1 1 0 Nodule-specific GRP repeat APG6 PF04111.7 EMC78417.1 - 1.2e-128 428.6 12.5 1.3e-128 428.4 8.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 BH3 PF15285.1 EMC78417.1 - 1.5e-14 53.0 0.2 3.2e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting DUF342 PF03961.8 EMC78417.1 - 0.00054 18.5 7.9 0.00087 17.8 5.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF342) IFT57 PF10498.4 EMC78417.1 - 0.0094 14.7 12.0 0.014 14.1 8.3 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 AAA_27 PF13514.1 EMC78417.1 - 0.16 9.6 13.4 0.2 9.2 9.3 1.0 1 0 0 1 1 1 0 AAA domain DUF740 PF05340.7 EMC78417.1 - 0.38 9.0 4.9 0.55 8.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF972 PF06156.8 EMC78417.1 - 0.43 10.9 15.6 0.15 12.4 7.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EMC78417.1 - 0.86 7.3 8.8 1.1 6.9 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.3 EMC78417.1 - 1.2 7.6 3.9 1.8 7.1 2.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CENP-F_leu_zip PF10473.4 EMC78417.1 - 1.8 8.4 26.4 0.18 11.6 10.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Transposase_22 PF02994.9 EMC78417.1 - 2.3 6.6 14.2 3.4 6.0 9.8 1.2 1 0 0 1 1 1 0 L1 transposable element GAS PF13851.1 EMC78417.1 - 3.4 6.8 26.0 0.11 11.6 7.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 EMC78417.1 - 6.2 6.0 16.5 1.2 8.2 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2968 PF11180.3 EMC78417.1 - 8.3 5.7 16.1 7 5.9 9.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) TMPIT PF07851.8 EMC78417.1 - 9.8 5.1 11.2 16 4.4 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cyclin_N PF00134.18 EMC78418.1 - 1.2e-10 41.0 0.8 6.9e-05 22.4 0.2 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF4327 PF14217.1 EMC78418.1 - 0.065 13.0 1.3 0.59 9.9 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4327) ESCRT-II PF05871.7 EMC78419.1 - 1.8e-29 102.4 0.3 2.4e-29 102.0 0.1 1.3 2 0 0 2 2 2 1 ESCRT-II complex subunit RAMP PF04901.8 EMC78420.1 - 6.3e-41 138.7 1.5 6.9e-41 138.5 1.0 1.0 1 0 0 1 1 1 1 Receptor activity modifying family 7tm_1 PF00001.16 EMC78421.1 - 9.3e-38 129.8 2.0 1.1e-37 129.5 1.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78421.1 - 1.1e-05 24.6 0.2 1.4e-05 24.4 0.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx V1R PF03402.9 EMC78421.1 - 0.12 11.8 1.7 0.094 12.0 0.3 1.5 2 0 0 2 2 2 0 Vomeronasal organ pheromone receptor family, V1R Tubulin PF00091.20 EMC78422.1 - 4.7e-54 183.4 0.0 8.7e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC78422.1 - 4.7e-48 162.3 0.1 8.8e-48 161.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Reticulon PF02453.12 EMC78423.1 - 0.0023 17.5 0.1 0.0023 17.5 0.0 1.6 2 0 0 2 2 2 1 Reticulon DUF4131 PF13567.1 EMC78423.1 - 0.0048 16.3 0.3 0.0048 16.3 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) TBPIP PF07106.8 EMC78424.1 - 5.3e-15 55.3 2.4 7.4e-15 54.9 1.7 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3600 PF12207.3 EMC78424.1 - 0.004 16.6 0.3 0.005 16.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3600) WEMBL PF05701.6 EMC78424.1 - 0.032 12.7 0.8 0.038 12.4 0.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Fmp27_WPPW PF10359.4 EMC78424.1 - 0.036 12.4 0.1 0.036 12.4 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ax_dynein_light PF10211.4 EMC78424.1 - 0.13 12.1 2.0 0.18 11.6 1.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain FlxA PF14282.1 EMC78424.1 - 0.15 12.0 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 FlxA-like protein CCDC-167 PF15188.1 EMC78424.1 - 0.56 10.1 3.6 0.79 9.7 2.2 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 HLH PF00010.21 EMC78425.1 - 6.4e-16 57.7 0.1 2.2e-15 56.0 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RNA_pol_Rpb4 PF03874.11 EMC78425.1 - 0.17 11.8 3.7 0.62 10.0 2.6 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb4 CoaE PF01121.15 EMC78426.1 - 2.9e-47 160.3 0.0 3.7e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EMC78426.1 - 6.9e-06 26.8 0.5 5e-05 24.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC78426.1 - 1.5e-05 24.8 0.3 0.00018 21.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EMC78426.1 - 0.0001 22.2 1.5 0.00072 19.5 1.0 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 EMC78426.1 - 0.00035 20.8 4.3 0.0047 17.2 3.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC78426.1 - 0.0022 17.1 1.5 0.013 14.6 1.0 2.2 1 1 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 EMC78426.1 - 0.008 15.1 0.0 0.01 14.8 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain AAA_28 PF13521.1 EMC78426.1 - 0.0088 16.0 6.2 0.28 11.1 1.4 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EMC78426.1 - 0.047 13.4 0.8 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain Pox_A32 PF04665.7 EMC78426.1 - 0.056 12.7 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_tran PF00005.22 EMC78426.1 - 0.083 13.1 0.4 0.18 12.1 0.1 1.6 2 1 0 2 2 2 0 ABC transporter adh_short PF00106.20 EMC78427.1 - 2.5e-14 53.5 0.0 4.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC78427.1 - 3.2e-06 27.1 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMC78427.1 - 3.5e-05 23.0 0.0 4.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EMC78427.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 KR domain V_ATPase_I PF01496.14 EMC78428.1 - 0 1095.5 0.2 0 1095.4 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PTRF_SDPR PF15237.1 EMC78429.1 - 1.1e-102 342.6 36.4 6.5e-101 336.8 25.2 2.2 1 1 0 1 1 1 1 PTRF/SDPR family Reo_sigmaC PF04582.7 EMC78429.1 - 0.0095 15.1 1.3 0.016 14.3 0.9 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EMC78429.1 - 0.41 10.4 12.3 0.38 10.5 4.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EMC78429.1 - 0.59 9.9 16.1 0.77 9.5 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliD_N PF02465.13 EMC78429.1 - 0.6 10.5 13.5 1.6 9.1 2.4 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FlaC_arch PF05377.6 EMC78429.1 - 0.9 9.4 10.6 21 5.1 0.1 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YjcZ PF13990.1 EMC78429.1 - 3.6 6.6 11.7 1.8 7.6 2.5 2.3 2 0 0 2 2 2 0 YjcZ-like protein STAT_bind PF02864.10 EMC78430.1 - 3.6e-128 426.4 0.4 2.9e-127 423.5 0.2 2.2 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.15 EMC78430.1 - 1.6e-58 197.3 18.1 3e-58 196.5 12.5 1.4 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.12 EMC78430.1 - 8.1e-42 142.1 8.1 8.1e-42 142.1 5.6 2.8 2 1 2 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.19 EMC78430.1 - 9e-14 51.0 0.0 2.4e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Syntaxin-6_N PF09177.6 EMC78430.1 - 0.0037 17.6 0.9 0.0037 17.6 0.6 2.9 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 EMC78430.1 - 0.54 10.0 9.9 0.24 11.2 4.0 2.1 2 0 0 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 EMC78430.1 - 0.62 10.1 13.6 0.24 11.5 6.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family eIF3_N PF09440.5 EMC78430.1 - 0.75 9.9 11.0 4.9 7.3 1.3 3.2 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain MerR-DNA-bind PF09278.6 EMC78430.1 - 1.4 9.3 14.0 1.6 9.1 0.3 4.0 4 0 0 4 4 4 0 MerR, DNA binding DUF342 PF03961.8 EMC78430.1 - 4.5 5.5 8.0 0.41 9.0 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Ras PF00071.17 EMC78432.1 - 1.4e-61 206.5 0.5 1.7e-61 206.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC78432.1 - 7.1e-20 71.6 0.1 1.3e-19 70.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC78432.1 - 4e-12 45.7 0.1 5e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC78432.1 - 2.1e-05 23.7 0.0 2.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC78432.1 - 9.8e-05 22.2 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC78432.1 - 0.00015 21.2 0.1 0.00038 19.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMC78432.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EMC78432.1 - 0.086 12.0 0.1 0.3 10.3 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit HSP20 PF00011.16 EMC78433.1 - 1.6e-16 60.0 0.0 2.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.16 EMC78434.1 - 8.4e-15 54.4 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RIG-I_C-RD PF11648.3 EMC78435.1 - 4.4e-41 139.6 2.4 9.6e-41 138.5 1.7 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I DEAD PF00270.24 EMC78435.1 - 3.8e-19 68.7 0.1 1.5e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC78435.1 - 7.4e-18 65.0 0.1 2.6e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMC78435.1 - 3.4e-17 62.0 0.1 8.4e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMC78435.1 - 4.5e-06 25.6 0.1 7.4e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 EMC78435.1 - 1.8e-05 24.4 0.9 0.048 13.2 0.8 2.8 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC78435.1 - 0.00037 20.6 1.7 0.0013 18.8 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EMC78435.1 - 0.0072 16.0 0.2 1.8 8.3 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain Zot PF05707.7 EMC78435.1 - 0.013 14.9 0.3 0.063 12.7 0.2 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) zf-met PF12874.2 EMC78436.1 - 6.2e-08 32.5 0.5 6.2e-08 32.5 0.3 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC78436.1 - 1.2e-05 25.2 0.3 1.2e-05 25.2 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding TRAM_LAG1_CLN8 PF03798.11 EMC78437.1 - 5.5e-15 55.4 10.1 5.5e-15 55.4 7.0 2.2 2 0 0 2 2 2 1 TLC domain Homeobox PF00046.24 EMC78437.1 - 7.1e-08 31.9 0.2 1.4e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_36 PF13730.1 EMC78437.1 - 0.008 16.2 0.2 0.35 11.0 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain Homez PF11569.3 EMC78437.1 - 0.096 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Toxin_25 PF08095.6 EMC78438.1 - 0.0062 16.2 48.3 17 5.2 0.2 10.0 10 0 0 10 10 10 9 Hefutoxin family Aldedh PF00171.17 EMC78439.1 - 4.7e-188 625.2 0.0 5.3e-188 625.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC78439.1 - 0.00026 19.8 0.0 0.00055 18.7 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMC78439.1 - 0.0057 15.9 0.1 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Pkinase PF00069.20 EMC78440.1 - 4.2e-43 147.3 0.0 7.8e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78440.1 - 3.2e-37 128.0 0.0 6.8e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.2 EMC78440.1 - 3.9e-27 93.3 33.5 5.6e-06 25.8 0.7 7.8 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC78440.1 - 3.2e-26 90.8 27.2 8.2e-10 38.3 1.7 6.7 6 0 0 6 6 6 5 Leucine rich repeat Ank_2 PF12796.2 EMC78440.1 - 6e-18 64.9 0.9 2.4e-09 37.3 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) LRR_1 PF00560.28 EMC78440.1 - 1.2e-16 58.1 25.6 1.2 9.4 0.4 11.5 12 0 0 12 12 10 5 Leucine Rich Repeat Miro PF08477.8 EMC78440.1 - 6.3e-10 39.5 0.0 1.8e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein LRR_7 PF13504.1 EMC78440.1 - 2.1e-09 36.0 27.5 0.19 12.0 0.1 11.2 12 0 0 12 12 10 2 Leucine rich repeat Ank_3 PF13606.1 EMC78440.1 - 6.3e-09 35.2 1.4 0.75 10.2 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 EMC78440.1 - 1.9e-08 33.7 3.5 0.062 13.1 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC78440.1 - 6.7e-07 29.3 3.8 1.5 9.1 0.0 4.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ras PF00071.17 EMC78440.1 - 1.5e-06 27.7 0.0 2.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Ank_4 PF13637.1 EMC78440.1 - 1.9e-06 28.2 0.4 0.042 14.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Arf PF00025.16 EMC78440.1 - 7.8e-06 25.2 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_6 PF13516.1 EMC78440.1 - 0.00012 21.7 21.7 0.028 14.4 0.1 9.2 10 0 0 10 10 10 1 Leucine Rich repeat MMR_HSR1 PF01926.18 EMC78440.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase CHGN PF05679.11 EMC78441.1 - 7.8e-19 67.7 0.5 9.2e-19 67.5 0.3 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 EMC78441.1 - 2.4e-14 53.1 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EMC78441.1 - 3e-05 23.7 0.1 0.00023 20.8 0.0 1.9 1 1 0 1 1 1 1 Galactosyltransferase Glyco_transf_21 PF13506.1 EMC78441.1 - 0.001 18.3 0.1 0.0035 16.6 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMC78441.1 - 0.042 13.5 0.0 0.32 10.6 0.0 2.3 2 1 1 3 3 3 0 Glycosyl transferase family 2 Selenoprotein_S PF06936.6 EMC78442.1 - 8.4e-57 191.7 7.5 9.2e-57 191.6 5.2 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) LRR_9 PF14580.1 EMC78443.1 - 6.1e-94 312.4 0.9 7.6e-94 312.1 0.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EMC78443.1 - 1.5e-11 43.6 4.7 1.3e-05 24.6 1.0 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC78443.1 - 2.3e-09 36.8 21.8 2.7e-05 23.8 2.8 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EMC78443.1 - 0.0021 17.8 4.8 5.4 7.4 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EMC78443.1 - 0.092 12.8 6.5 2.7 8.3 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 EMC78443.1 - 0.11 12.7 4.8 20 5.9 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat Peptidase_S8 PF00082.17 EMC78444.1 - 1.3e-55 188.5 0.3 1.7e-55 188.1 0.2 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EMC78444.1 - 2.5e-33 113.6 0.1 4.3e-33 112.9 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.1 EMC78444.1 - 6.8e-14 51.6 91.9 8.3e-10 38.3 23.5 4.0 1 1 3 4 4 4 3 Growth factor receptor domain IV PLAC PF08686.6 EMC78444.1 - 2.7e-09 37.1 10.1 1.9e-08 34.4 7.0 2.7 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain VSP PF03302.8 EMC78444.1 - 0.42 9.1 57.4 0.043 12.4 7.4 3.9 1 1 3 4 4 4 0 Giardia variant-specific surface protein PH PF00169.24 EMC78445.1 - 1.9e-11 44.0 0.5 2.9e-11 43.4 0.4 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EMC78445.1 - 0.0002 21.4 0.3 0.018 15.1 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain CAP-ZIP_m PF15255.1 EMC78445.1 - 0.001 18.9 0.4 0.0016 18.3 0.3 1.5 1 1 0 1 1 1 1 WASH complex subunit CAP-Z interacting, central region PH_11 PF15413.1 EMC78445.1 - 0.0063 16.7 1.3 0.041 14.1 0.9 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EMC78445.1 - 0.0083 16.0 0.1 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Ank_4 PF13637.1 EMC78446.1 - 6.9e-26 90.1 7.0 7.1e-11 42.3 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC78446.1 - 3.7e-23 81.6 1.1 5.3e-11 42.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC78446.1 - 8.1e-19 66.4 1.6 1.7e-05 24.3 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EMC78446.1 - 3.9e-17 61.8 4.2 7.2e-07 29.2 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC78446.1 - 2.5e-15 55.0 1.1 8.7e-05 22.4 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Collagen PF01391.13 EMC78447.1 - 6.2e-41 137.7 213.1 1e-06 28.1 20.0 8.0 1 1 4 5 5 5 4 Collagen triple helix repeat (20 copies) VWA PF00092.23 EMC78447.1 - 6e-27 94.5 1.3 8.6e-27 93.9 0.9 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC78447.1 - 1.4e-10 41.5 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC78447.1 - 0.0042 16.7 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Rep_fac-A_3 PF08661.6 EMC78449.1 - 3.1e-21 75.3 0.0 3.4e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 FAM117 PF15388.1 EMC78451.1 - 6.2e-121 403.5 23.4 6.2e-121 403.5 16.2 1.9 1 1 1 2 2 2 1 Protein Family FAM117 DUF1192 PF06698.6 EMC78451.1 - 0.21 11.3 3.2 6.5 6.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Neurexophilin PF06312.7 EMC78452.1 - 1.2e-112 374.5 3.2 1.5e-112 374.1 2.2 1.1 1 0 0 1 1 1 1 Neurexophilin NigD PF12667.2 EMC78452.1 - 0.034 13.9 0.2 0.083 12.6 0.0 1.7 1 1 1 2 2 2 0 NigD-like protein Filamin PF00630.14 EMC78452.1 - 0.05 14.1 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 Filamin/ABP280 repeat Nepo_coat_C PF03688.9 EMC78452.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain B12D PF06522.6 EMC78453.1 - 6.4e-28 96.2 0.0 6.9e-28 96.1 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Keratin PF02422.11 EMC78454.1 - 7e-19 67.6 19.7 2e-18 66.1 13.6 1.6 1 1 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC78454.1 - 0.068 13.1 5.9 0.085 12.8 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 EMC78455.1 - 2e-27 95.0 15.0 2.3e-27 94.7 10.4 1.1 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC78455.1 - 0.0059 16.6 10.8 0.0075 16.2 7.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3432) Cornifin PF02389.10 EMC78455.1 - 0.0061 16.3 3.8 0.0071 16.1 2.7 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family zf-Tim10_DDP PF02953.10 EMC78455.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Keratin PF02422.11 EMC78456.1 - 3e-30 104.0 16.0 3.3e-30 103.9 11.1 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC78456.1 - 0.036 14.0 9.4 0.045 13.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) zf-Tim10_DDP PF02953.10 EMC78456.1 - 0.11 11.7 0.4 0.17 11.1 0.3 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Keratin PF02422.11 EMC78457.1 - 3.4e-27 94.2 15.1 4.1e-27 94.0 10.4 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC78457.1 - 0.016 15.2 5.3 0.021 14.8 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Pyridoxal_deC PF00282.14 EMC78458.1 - 1.6e-112 375.6 0.0 1.9e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMC78458.1 - 2.2e-06 26.6 0.0 1.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC78458.1 - 4.6e-05 22.7 0.0 5.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EMC78458.1 - 0.085 11.3 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF1749 PF08538.5 EMC78458.1 - 0.16 10.8 0.2 0.34 9.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) PSP1 PF04468.7 EMC78459.1 - 0.017 15.0 0.3 0.052 13.5 0.1 1.9 2 0 0 2 2 2 0 PSP1 C-terminal conserved region STT3 PF02516.9 EMC78460.1 - 4.1e-122 408.5 25.2 5.4e-122 408.2 17.5 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Oxysterol_BP PF01237.13 EMC78461.1 - 5.1e-72 242.3 0.2 1.3e-71 240.9 0.1 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EMC78461.1 - 2.1e-08 34.1 0.0 4.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMC78461.1 - 0.00015 21.9 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 EMC78461.1 - 0.0094 16.0 0.0 0.035 14.1 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain NAD_Gly3P_dh_N PF01210.18 EMC78462.1 - 1.1e-46 158.3 0.1 1.4e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EMC78462.1 - 0.015 15.7 0.1 0.058 13.8 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.10 EMC78462.1 - 0.087 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain MARVEL PF01284.18 EMC78463.1 - 1.3e-14 54.2 18.8 1.5e-14 54.0 13.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EMC78463.1 - 0.41 10.1 10.8 0.53 9.8 7.0 1.5 1 1 0 1 1 1 0 SUR7/PalI family NfeD PF01957.13 EMC78463.1 - 2.3 8.3 6.6 1.9 8.6 4.1 1.3 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding EmrE PF13536.1 EMC78463.1 - 5.9 7.1 14.8 12 6.0 0.1 2.2 1 1 1 2 2 2 0 Multidrug resistance efflux transporter AKAP2_C PF15304.1 EMC78464.1 - 2e-19 70.4 11.4 2e-19 70.4 7.9 3.2 2 1 1 3 3 3 1 A-kinase anchor protein 2 C-terminus Misat_Tub_SegII PF10644.4 EMC78464.1 - 0.032 14.2 0.1 0.19 11.7 0.1 2.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain RII_binding_1 PF10522.4 EMC78464.1 - 0.033 14.2 0.4 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 RII binding domain PX PF00787.19 EMC78465.1 - 4.9e-23 81.0 1.9 9.8e-23 80.1 1.3 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EMC78465.1 - 2.2e-12 46.7 0.0 7.6e-09 35.1 0.0 2.4 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.13 EMC78465.1 - 2.9e-08 33.5 1.7 3.2e-08 33.3 0.3 1.7 2 0 0 2 2 2 1 BAR domain BAR_3_WASP_bdg PF10456.4 EMC78465.1 - 0.0045 16.2 0.2 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein DUF842 PF05811.8 EMC78465.1 - 0.41 10.1 3.9 1.8 8.0 0.5 2.3 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cache_2 PF08269.6 EMC78466.1 - 0.039 13.9 0.1 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Cache domain SCP2 PF02036.12 EMC78468.1 - 2.7e-23 82.2 0.0 5.6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family adh_short PF00106.20 EMC78468.1 - 2.2e-17 63.4 0.0 3.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC78468.1 - 5.4e-09 36.1 0.0 7.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC78468.1 - 8.4e-06 25.5 0.6 1.7e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 EMC78468.1 - 0.00024 21.0 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Toprim_C_rpt PF13368.1 EMC78468.1 - 0.0034 17.8 0.0 0.0088 16.5 0.0 1.7 1 0 0 1 1 1 1 Topoisomerase C-terminal repeat DUF1942 PF09167.6 EMC78468.1 - 0.085 12.6 0.2 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) Eno-Rase_NADH_b PF12242.3 EMC78468.1 - 0.78 9.5 3.5 0.62 9.8 0.2 2.4 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_5 PF13893.1 EMC78469.1 - 2.2e-45 152.3 0.6 3.9e-14 52.2 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78469.1 - 1.1e-30 105.4 0.1 1.4e-08 34.5 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC78469.1 - 2.5e-24 84.7 0.0 3e-08 33.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EGF_CA PF07645.10 EMC78471.1 - 7.3e-17 61.0 46.3 1e-09 38.2 5.1 4.5 4 0 0 4 4 4 2 Calcium-binding EGF domain Sushi PF00084.15 EMC78471.1 - 2.2e-14 53.5 10.0 2.2e-08 34.2 0.6 5.4 5 0 0 5 5 5 2 Sushi domain (SCR repeat) EGF_3 PF12947.2 EMC78471.1 - 5.2e-13 48.7 41.4 9.8e-06 25.4 5.2 4.6 4 0 0 4 4 3 3 EGF domain cEGF PF12662.2 EMC78471.1 - 5.6e-13 48.2 24.4 2.2e-08 33.5 1.5 4.5 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.2 EMC78471.1 - 3.4e-06 26.7 27.5 0.00029 20.5 4.7 3.8 3 0 0 3 3 3 3 MSP1 EGF domain 1 FXa_inhibition PF14670.1 EMC78471.1 - 1e-05 25.5 35.6 0.0016 18.4 5.1 4.5 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site Cas_DxTHG PF09455.5 EMC78471.1 - 0.014 14.5 0.2 0.03 13.4 0.0 1.5 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family TMEM190 PF15431.1 EMC78471.1 - 0.016 15.1 0.6 0.016 15.1 0.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 190 hEGF PF12661.2 EMC78471.1 - 0.07 13.2 7.7 13 6.0 0.1 4.5 3 0 0 3 3 3 0 Human growth factor-like EGF DUF4165 PF13752.1 EMC78471.1 - 0.076 12.7 0.5 4.3 7.1 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4165) fn3 PF00041.16 EMC78471.1 - 0.086 12.9 0.0 12 6.1 0.0 3.2 3 0 0 3 3 3 0 Fibronectin type III domain G-gamma PF00631.17 EMC78472.1 - 4.2e-16 58.4 0.0 4.7e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain SurA_N_3 PF13624.1 EMC78473.1 - 0.0034 17.3 1.4 0.041 13.8 0.1 2.1 2 0 0 2 2 2 1 SurA N-terminal domain Tmemb_161AB PF10268.4 EMC78473.1 - 0.026 13.0 0.2 0.044 12.3 0.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB AsmA_1 PF13109.1 EMC78473.1 - 0.039 13.2 1.1 0.061 12.5 0.1 1.7 2 0 0 2 2 2 0 AsmA-like C-terminal region DUF3984 PF13136.1 EMC78474.1 - 0.013 14.7 0.2 0.32 10.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) DUF834 PF05754.9 EMC78474.1 - 0.18 11.6 0.8 26 4.7 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF834) Trypsin PF00089.21 EMC78475.1 - 2e-49 168.1 0.0 2.2e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC78475.1 - 6.6e-06 25.5 0.0 8.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF551 PF04448.7 EMC78475.1 - 0.0049 17.5 0.1 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF551) Trypsin_2 PF13365.1 EMC78475.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain PMSR PF01625.16 EMC78476.1 - 9.1e-49 165.3 0.8 1e-48 165.1 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cornifin PF02389.10 EMC78477.1 - 0.0011 18.7 2.2 0.0016 18.2 1.5 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family Ric8 PF10165.4 EMC78477.1 - 0.88 8.3 12.3 1.7 7.3 1.5 2.4 1 1 1 2 2 2 0 Guanine nucleotide exchange factor synembryn HNF-1_N PF04814.8 EMC78478.1 - 3e-11 43.7 2.0 3e-11 43.7 1.4 3.2 3 1 0 3 3 3 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 EMC78478.1 - 1.5e-10 40.5 0.6 1.5e-10 40.5 0.4 2.7 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 EMC78478.1 - 9e-05 22.0 0.9 0.0033 17.1 0.0 3.0 3 0 0 3 3 3 1 Homeobox KN domain HTH_37 PF13744.1 EMC78478.1 - 0.00082 19.1 0.5 0.00082 19.1 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EMC78478.1 - 0.0019 18.2 0.3 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.17 EMC78478.1 - 0.0027 17.5 0.1 0.0063 16.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix CUT PF02376.10 EMC78478.1 - 0.014 15.2 0.1 0.04 13.7 0.1 1.8 1 0 0 1 1 1 0 CUT domain HTH_24 PF13412.1 EMC78478.1 - 0.043 13.2 0.0 0.18 11.2 0.0 2.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DSBA PF01323.15 EMC78478.1 - 0.058 12.9 0.2 1 8.8 0.0 2.8 3 0 0 3 3 3 0 DSBA-like thioredoxin domain HTH_31 PF13560.1 EMC78478.1 - 0.093 12.9 4.1 0.12 12.5 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_26 PF13443.1 EMC78478.1 - 0.13 12.5 0.0 0.45 10.7 0.0 2.0 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.1 EMC78478.1 - 0.22 11.2 3.1 0.29 10.8 0.1 2.7 3 0 0 3 3 3 0 Homeodomain-like domain Pex14_N PF04695.8 EMC78478.1 - 0.35 10.9 5.8 0.2 11.6 1.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Beta-Casp PF10996.3 EMC78479.1 - 2.3e-11 43.6 0.0 4.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Glyco_transf_64 PF09258.5 EMC78481.1 - 1.5e-97 325.5 0.1 2.7e-97 324.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 EMC78481.1 - 1.1e-52 178.9 0.0 1.7e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Exostosin family ADIP PF11559.3 EMC78481.1 - 0.0079 16.1 7.7 0.014 15.3 5.3 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 EMC78481.1 - 0.042 13.8 5.1 0.084 12.8 3.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EMC78481.1 - 0.047 13.4 2.5 0.094 12.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 EMC78481.1 - 0.21 12.0 0.4 0.47 10.9 0.3 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.6 EMC78481.1 - 0.23 10.0 4.9 0.43 9.1 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Noelin-1 PF12308.3 EMC78481.1 - 0.41 10.4 1.9 1.1 9.1 1.2 1.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein HR1 PF02185.11 EMC78481.1 - 0.42 10.3 6.2 2 8.1 2.3 2.5 2 0 0 2 2 2 0 Hr1 repeat TPR_MLP1_2 PF07926.7 EMC78481.1 - 1.8 8.2 12.4 0.23 11.2 5.8 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein EF-hand_1 PF00036.27 EMC78482.1 - 3.3e-12 44.7 6.6 2.7e-05 23.1 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 EMC78482.1 - 4e-12 44.9 2.4 6.8e-05 22.4 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 EMC78482.1 - 9.3e-10 38.5 3.3 0.00031 20.8 0.2 3.5 2 1 1 3 3 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC78482.1 - 9.8e-10 37.9 5.5 7.1e-06 25.5 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC78482.1 - 6.2e-09 34.7 3.3 4.6e-06 25.7 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 EMC78482.1 - 1.6e-05 24.5 0.5 0.0097 15.6 0.1 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Peptidase_C23 PF05379.6 EMC78482.1 - 0.2 11.6 1.0 2.6 8.0 0.1 2.8 3 1 0 3 3 3 0 Carlavirus endopeptidase DUF3791 PF12668.2 EMC78483.1 - 0.015 14.8 0.0 0.017 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF2415 PF10313.4 EMC78483.1 - 0.016 14.8 0.3 0.022 14.4 0.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SPAN-X PF07458.7 EMC78483.1 - 0.092 12.9 0.0 0.092 12.9 0.0 1.0 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome DUF1977 PF09320.6 EMC78484.1 - 1e-41 141.4 0.2 1.8e-41 140.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EMC78484.1 - 2.8e-27 94.2 1.3 4.4e-27 93.5 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EMC78484.1 - 0.06 12.7 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein KH_1 PF00013.24 EMC78485.1 - 2.2e-12 46.4 0.9 3.4e-12 45.8 0.7 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC78485.1 - 3.1e-09 36.2 1.1 9e-09 34.7 0.5 1.9 2 0 0 2 2 2 1 KH domain AKAP7_NLS PF10469.4 EMC78485.1 - 0.00012 21.8 0.2 0.00018 21.3 0.1 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_2 PF07650.12 EMC78485.1 - 0.0049 16.4 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 KH domain MTS_N PF08468.6 EMC78485.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal AKAP7_NLS PF10469.4 EMC78486.1 - 4.9e-15 55.7 0.1 5.9e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain SPARC_Ca_bdg PF10591.4 EMC78487.1 - 3.9e-28 97.7 0.0 7.5e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.13 EMC78487.1 - 3.6e-16 58.2 3.7 3.6e-16 58.2 2.6 2.4 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.10 EMC78487.1 - 1.5e-09 37.6 6.9 4.6e-09 36.0 4.8 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC78487.1 - 9.5e-07 28.7 5.7 9.5e-07 28.7 3.9 2.6 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 EMC78487.1 - 8.7e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC78487.1 - 0.00038 20.0 0.0 0.45 10.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMC78487.1 - 0.00092 18.3 0.0 0.28 10.5 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EMC78487.1 - 0.03 13.6 0.0 0.27 10.6 0.0 2.6 3 0 0 3 3 3 0 EF hand EF-hand_10 PF14788.1 EMC78487.1 - 0.039 13.6 0.1 0.32 10.6 0.0 2.1 1 1 1 2 2 2 0 EF hand EF-hand_8 PF13833.1 EMC78487.1 - 0.045 13.3 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Cadherin PF00028.12 EMC78488.1 - 1.2e-49 166.4 0.0 2.1e-19 69.5 0.0 4.1 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.7 EMC78488.1 - 0.00024 20.5 0.0 0.067 12.7 0.0 3.3 3 1 0 3 3 3 1 Cadherin-like Pkinase PF00069.20 EMC78489.1 - 4.6e-65 219.3 0.0 7.8e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78489.1 - 2.5e-37 128.3 0.0 3.5e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 EMC78489.1 - 5.5e-28 96.6 0.2 9.6e-28 95.8 0.1 1.4 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 EMC78489.1 - 4.2e-17 61.6 16.2 1.1e-15 57.1 3.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC78489.1 - 7.5e-08 32.7 0.4 1.8e-07 31.5 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC78489.1 - 0.017 14.0 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C1_3 PF07649.7 EMC78489.1 - 0.08 12.9 17.3 0.031 14.3 3.9 3.0 2 0 0 2 2 2 0 C1-like domain PMP22_Claudin PF00822.15 EMC78490.1 - 7.3e-22 77.7 3.9 1.8e-21 76.5 2.7 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC78490.1 - 2.1e-19 69.8 3.1 2.9e-19 69.3 2.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 EMC78490.1 - 4.1e-05 22.9 2.7 8.1e-05 21.9 1.7 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF716 PF04819.7 EMC78490.1 - 0.043 13.2 0.5 0.083 12.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF716) SUR7 PF06687.7 EMC78490.1 - 0.89 9.0 13.0 3.9 6.9 8.3 2.3 1 1 1 2 2 2 0 SUR7/PalI family Claudin_3 PF06653.6 EMC78490.1 - 1.2 8.8 9.7 3.1 7.5 6.8 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like MFS_1 PF07690.11 EMC78490.1 - 2.7 6.6 15.1 24 3.4 10.6 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily CD20 PF04103.10 EMC78490.1 - 5.6 6.8 12.6 5.7 6.8 0.1 3.1 2 1 1 3 3 3 0 CD20-like family PMP22_Claudin PF00822.15 EMC78491.1 - 1.9e-24 86.1 0.0 3.6e-24 85.2 0.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC78491.1 - 1.9e-11 43.9 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.1 EMC78491.1 - 0.0016 17.0 0.2 0.0021 16.6 0.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2269 PF10027.4 EMC78491.1 - 0.0048 16.7 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) Polysacc_synt_3 PF13440.1 EMC78491.1 - 0.017 14.6 0.1 0.04 13.3 0.1 1.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein TMEM173 PF15009.1 EMC78491.1 - 0.034 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 DUF4225 PF13988.1 EMC78491.1 - 0.038 13.4 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DuoxA PF10204.4 EMC78491.1 - 0.093 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor Claudin_2 PF13903.1 EMC78492.1 - 1.5e-29 102.8 5.6 2.1e-29 102.4 3.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC78492.1 - 7e-16 58.3 9.9 1.3e-09 37.9 3.9 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF805 PF05656.9 EMC78492.1 - 0.00012 21.8 0.7 0.00012 21.8 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF805) EpsG PF14897.1 EMC78492.1 - 0.013 14.4 0.9 0.013 14.4 0.6 2.0 3 0 0 3 3 3 0 EpsG family DUF1049 PF06305.6 EMC78492.1 - 0.022 14.2 0.0 0.022 14.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF606 PF04657.8 EMC78492.1 - 0.029 14.4 3.0 0.85 9.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF606 Claudin_3 PF06653.6 EMC78492.1 - 0.037 13.7 7.2 0.26 11.0 2.6 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like zf-LITAF-like PF10601.4 EMC78492.1 - 0.043 13.6 2.5 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF981 PF06168.6 EMC78492.1 - 0.065 13.0 4.6 0.22 11.2 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF981) DUF3902 PF13042.1 EMC78492.1 - 0.12 11.6 6.8 0.02 14.1 2.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3902) DUF3040 PF11239.3 EMC78492.1 - 1.4 9.0 5.6 4.8 7.2 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3040) DUF983 PF06170.7 EMC78492.1 - 2.7 8.1 6.1 7.7 6.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF983) DUF1469 PF07332.6 EMC78492.1 - 3.3 7.4 9.6 7.9 6.2 0.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1469) AAA_12 PF13087.1 EMC78493.1 - 1.1e-34 119.6 1.1 1.4e-33 115.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMC78493.1 - 3.7e-29 101.9 7.4 3.5e-15 56.2 0.1 3.6 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 EMC78493.1 - 7.3e-09 35.4 0.0 1.1e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC78493.1 - 2e-08 33.8 0.0 7.9e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain zf-CCCH PF00642.19 EMC78493.1 - 7.4e-08 31.9 0.7 1.8e-07 30.6 0.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PhoH PF02562.11 EMC78493.1 - 2.2e-05 23.7 0.0 0.017 14.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 EMC78493.1 - 8.8e-05 21.9 0.0 8.8e-05 21.9 0.0 2.8 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EMC78493.1 - 0.00013 21.8 0.1 0.00091 19.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PAM2 PF07145.10 EMC78493.1 - 0.00063 19.0 1.3 0.0011 18.2 0.0 2.3 2 0 0 2 2 1 1 Ataxin-2 C-terminal region AAA_14 PF13173.1 EMC78493.1 - 0.0021 17.9 0.1 0.56 10.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain UvrD_C PF13361.1 EMC78493.1 - 0.011 15.2 0.6 0.16 11.4 0.0 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EMC78493.1 - 0.019 15.1 0.2 0.18 11.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMC78493.1 - 0.033 14.1 0.2 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Helicase_RecD PF05127.9 EMC78493.1 - 0.039 13.5 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 Helicase AAA_5 PF07728.9 EMC78493.1 - 0.13 12.0 0.2 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMC78493.1 - 0.17 11.2 0.0 0.48 9.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PCI PF01399.22 EMC78494.1 - 8.3e-23 80.7 1.8 3e-22 78.9 0.0 2.7 2 1 0 2 2 2 1 PCI domain Tubulin_C PF03953.12 EMC78494.1 - 0.043 13.8 0.1 0.21 11.6 0.0 2.2 1 1 1 2 2 2 0 Tubulin C-terminal domain Hydrophob_seed PF14547.1 EMC78494.1 - 0.064 13.1 0.1 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Hydrophobic seed protein IP_trans PF02121.13 EMC78495.1 - 9.1e-67 224.8 7.7 4.3e-66 222.6 5.3 1.8 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein Utp12 PF04003.7 EMC78496.1 - 0.0026 17.6 0.9 0.0075 16.1 0.2 2.2 2 0 0 2 2 2 1 Dip2/Utp12 Family UTP15_C PF09384.5 EMC78496.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 UTP15 C terminal DUF2309 PF10070.4 EMC78496.1 - 0.13 10.3 0.0 2.2 6.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2309) DDT PF02791.12 EMC78497.1 - 4.5e-22 77.5 0.3 9.9e-22 76.4 0.2 1.6 1 0 0 1 1 1 1 DDT domain PHD PF00628.24 EMC78497.1 - 8.2e-09 35.0 13.6 3.2e-08 33.1 9.4 2.1 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.1 EMC78497.1 - 3.3e-06 26.7 0.0 9.1e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 EMC78497.1 - 0.00049 19.9 0.3 0.0017 18.2 0.2 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Prok-RING_1 PF14446.1 EMC78497.1 - 0.055 13.2 12.2 0.024 14.3 5.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Bromodomain PF00439.20 EMC78498.1 - 7.7e-27 93.0 0.1 2.1e-26 91.6 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 EMC78498.1 - 4e-10 39.2 7.3 4e-10 39.2 5.0 1.9 2 0 0 2 2 2 1 PHD-finger Ogr_Delta PF04606.7 EMC78498.1 - 7.5 6.2 7.6 9.7 5.9 2.2 2.9 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger NTR PF01759.16 EMC78499.1 - 0.012 15.2 0.1 0.038 13.5 0.1 1.7 1 1 0 1 1 1 0 UNC-6/NTR/C345C module CEP44 PF15007.1 EMC78500.1 - 8e-44 148.5 0.7 2.2e-43 147.1 0.5 1.8 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 adh_short PF00106.20 EMC78501.1 - 3.8e-35 121.2 0.3 5.3e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC78501.1 - 1.2e-16 60.9 0.1 1.7e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC78501.1 - 5.9e-15 55.6 0.0 9.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMC78501.1 - 1.5e-08 34.3 0.1 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMC78501.1 - 1.4e-05 24.4 0.3 2.3e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMC78501.1 - 2.4e-05 23.1 0.3 3.3e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC78501.1 - 2.7e-05 24.2 0.1 4.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMC78501.1 - 0.0039 16.1 0.1 0.0059 15.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EMC78501.1 - 0.0042 16.1 0.1 0.0064 15.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_31 PF13847.1 EMC78501.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EMC78501.1 - 0.12 11.5 0.1 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMC78501.1 - 0.16 11.6 0.3 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Neur_chan_memb PF02932.11 EMC78502.1 - 1.1e-43 149.8 7.8 1.5e-37 129.7 2.5 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC78502.1 - 8.4e-43 146.0 0.4 1.3e-42 145.3 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain UPAR_LY6 PF00021.16 EMC78503.1 - 6.6e-10 39.2 16.7 8.7e-10 38.8 11.6 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 EMC78503.1 - 0.024 14.9 14.3 0.043 14.1 9.9 1.5 1 0 0 1 1 1 0 Snake toxin DUF1644 PF07800.7 EMC78503.1 - 3.8 7.3 11.0 83 2.9 7.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) UPAR_LY6 PF00021.16 EMC78504.1 - 8.4e-10 38.9 13.6 1.1e-09 38.6 9.4 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 EMC78504.1 - 0.012 15.9 12.1 0.022 15.1 8.4 1.5 1 0 0 1 1 1 0 Snake toxin UPAR_LY6 PF00021.16 EMC78505.1 - 6.4e-14 52.1 9.4 7.7e-14 51.8 6.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 EMC78505.1 - 0.014 15.7 7.8 0.023 15.0 5.4 1.4 1 1 0 1 1 1 0 Snake toxin UPAR_LY6 PF00021.16 EMC78506.1 - 8.5e-07 29.3 11.6 1.2e-06 28.7 8.1 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain IL4 PF00727.13 EMC78506.1 - 0.29 10.9 1.8 0.34 10.8 1.2 1.2 1 0 0 1 1 1 0 Interleukin 4 BAMBI PF06211.7 EMC78506.1 - 0.31 11.0 8.0 0.59 10.1 5.6 1.5 1 1 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.18 EMC78506.1 - 2.8 8.6 13.4 11 6.7 9.3 1.9 1 1 0 1 1 1 0 Activin types I and II receptor domain Toxin_1 PF00087.16 EMC78506.1 - 4 7.8 14.3 12 6.3 9.9 1.9 1 1 0 1 1 1 0 Snake toxin UPAR_LY6 PF00021.16 EMC78507.1 - 8.8e-05 22.8 11.8 0.00012 22.4 8.2 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain UPAR_LY6 PF00021.16 EMC78508.1 - 9.2e-06 26.0 15.1 1.2e-05 25.6 10.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 EMC78508.1 - 0.017 15.4 13.8 0.028 14.7 9.5 1.4 1 0 0 1 1 1 0 Snake toxin Activin_recp PF01064.18 EMC78508.1 - 0.11 13.1 16.7 0.22 12.2 11.6 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain Disintegrin PF00200.18 EMC78508.1 - 2.7 8.2 15.8 0.82 9.9 4.1 2.2 2 0 0 2 2 2 0 Disintegrin MORN PF02493.15 EMC78509.1 - 8.5e-36 119.5 45.6 1.1e-09 37.4 2.5 7.9 8 0 0 8 8 8 7 MORN repeat RicinB_lectin_2 PF14200.1 EMC78509.1 - 0.084 13.2 0.5 3 8.2 0.0 2.4 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Vmethyltransf PF01660.12 EMC78509.1 - 0.25 9.9 1.1 0.35 9.4 0.8 1.2 1 0 0 1 1 1 0 Viral methyltransferase Trypsin PF00089.21 EMC78510.1 - 4.1e-71 239.0 0.7 5.9e-71 238.5 0.5 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 EMC78510.1 - 1.2e-26 92.8 1.6 2.4e-26 91.8 1.1 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.13 EMC78510.1 - 6.8e-09 35.9 1.7 1.7e-08 34.7 0.3 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.13 EMC78510.1 - 2.4e-06 27.3 7.0 6.9e-06 25.8 4.9 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.6 EMC78510.1 - 1.1e-05 24.8 0.1 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Hepsin-SRCR PF09272.5 EMC78510.1 - 0.0005 20.2 0.6 0.0015 18.6 0.4 1.8 1 0 0 1 1 1 1 Hepsin, SRCR Trypsin_2 PF13365.1 EMC78510.1 - 0.0036 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trefoil PF00088.13 EMC78511.1 - 2.4e-30 103.8 21.9 3.3e-15 55.4 4.9 2.1 2 0 0 2 2 2 2 Trefoil (P-type) domain ABC2_membrane PF01061.19 EMC78512.1 - 2.3e-44 151.0 25.8 3.6e-44 150.4 17.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMC78512.1 - 4.8e-30 104.6 0.0 7.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC78512.1 - 9.6e-11 42.1 0.0 3.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EMC78512.1 - 1.5e-06 27.5 0.0 5.7e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMC78512.1 - 6.5e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC78512.1 - 0.002 18.9 0.0 0.0054 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC78512.1 - 0.0021 18.0 0.1 0.0051 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMC78512.1 - 0.0025 17.2 0.3 0.0058 16.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EMC78512.1 - 0.0029 16.7 20.3 0.0029 16.7 14.1 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_10 PF12846.2 EMC78512.1 - 0.0065 15.9 0.0 0.021 14.2 0.1 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EMC78512.1 - 0.014 15.5 0.1 0.049 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMC78512.1 - 0.027 14.8 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMC78512.1 - 0.027 14.4 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EMC78512.1 - 0.067 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMC78512.1 - 0.076 12.4 0.8 0.16 11.3 0.3 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMC78512.1 - 0.082 12.8 0.6 2.3 8.1 0.1 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EMC78512.1 - 0.096 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EMC78512.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 EMC78512.1 - 0.12 10.7 0.0 2.6 6.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMC78512.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EMC78512.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF1440 PF07274.7 EMC78512.1 - 1.1 9.2 4.1 8.2 6.4 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1440) BTB PF00651.26 EMC78513.1 - 5e-26 90.8 0.2 5.8e-26 90.6 0.1 1.0 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 EMC78513.1 - 7.2e-06 25.3 0.1 8.4e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB_2 PF02214.17 EMC78513.1 - 5e-05 23.4 0.0 6.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF1722 PF08349.6 EMC78513.1 - 0.0086 15.9 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1722) Stathmin PF00836.14 EMC78514.1 - 4.1e-54 182.0 11.1 4.6e-54 181.8 7.7 1.0 1 0 0 1 1 1 1 Stathmin family HTH_8 PF02954.14 EMC78514.1 - 0.046 13.2 0.6 0.046 13.2 0.4 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family CDC37_N PF03234.9 EMC78514.1 - 0.047 14.0 4.4 0.061 13.6 3.0 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding RNA_pol_Rpb1_4 PF05000.12 EMC78514.1 - 0.24 11.1 1.2 0.33 10.7 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 AAA_23 PF13476.1 EMC78514.1 - 1.6 8.9 6.3 1.8 8.8 4.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3886 PF13025.1 EMC78514.1 - 2.2 8.2 13.6 4.9 7.1 9.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) HlyIII PF03006.15 EMC78515.1 - 1.8e-42 145.2 16.0 2.6e-42 144.7 11.1 1.3 1 0 0 1 1 1 1 Haemolysin-III related Mito_fiss_reg PF05308.6 EMC78516.1 - 3.7e-84 282.0 1.6 4.4e-84 281.7 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator PID PF00640.18 EMC78518.1 - 1.5e-19 70.3 0.5 2.2e-19 69.8 0.3 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.1 EMC78518.1 - 3.4e-17 62.6 0.0 4.4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 EMC78518.1 - 2e-07 30.9 0.1 3.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Ammonium_transp PF00909.16 EMC78519.1 - 1.6e-50 171.7 26.3 3.5e-49 167.3 18.8 1.8 1 1 1 2 2 2 2 Ammonium Transporter Family GWT1 PF06423.7 EMC78519.1 - 4.1e-05 23.7 0.2 4.1e-05 23.7 0.1 2.8 3 2 1 4 4 4 1 GWT1 UPF0220 PF05255.6 EMC78520.1 - 8.6e-52 174.7 3.5 9.5e-52 174.5 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4064 PF13273.1 EMC78520.1 - 0.11 12.6 2.0 0.36 10.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SYF2 PF08231.7 EMC78522.1 - 1.8e-53 180.7 11.8 1.8e-53 180.7 8.2 1.4 2 0 0 2 2 2 1 SYF2 splicing factor FUSC-like PF12805.2 EMC78522.1 - 0.027 13.3 0.4 0.039 12.8 0.3 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS rve_3 PF13683.1 EMC78522.1 - 0.032 13.7 0.2 0.88 9.1 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain CENP-Q PF13094.1 EMC78522.1 - 0.12 12.3 9.4 0.88 9.5 5.3 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ARD PF03079.9 EMC78522.1 - 7.5 6.4 12.0 0.47 10.3 0.5 2.4 1 1 2 3 3 3 0 ARD/ARD' family Runt PF00853.14 EMC78523.1 - 6.8e-79 261.8 0.2 9.7e-79 261.3 0.2 1.2 1 0 0 1 1 1 1 Runt domain RunxI PF08504.6 EMC78523.1 - 2.8e-46 156.1 6.5 2.8e-46 156.1 4.5 1.9 2 0 0 2 2 2 1 Runx inhibition domain GST_N_3 PF13417.1 EMC78524.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC78524.1 - 4.3e-05 23.3 0.0 7.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC78524.1 - 5.1e-05 23.1 0.0 9.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC78524.1 - 0.0015 18.9 0.0 0.0038 17.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC78524.1 - 0.002 18.1 0.2 0.026 14.5 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2976 PF11190.3 EMC78525.1 - 0.0015 18.0 0.1 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2976) DUF3609 PF12259.3 EMC78525.1 - 0.005 15.5 0.1 0.0061 15.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) Rifin_STEVOR PF02009.11 EMC78525.1 - 0.0053 16.4 0.2 0.0061 16.2 0.2 1.1 1 0 0 1 1 1 1 Rifin/stevor family SKG6 PF08693.5 EMC78525.1 - 0.0068 15.6 2.3 0.011 15.0 1.6 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 EMC78525.1 - 0.012 15.1 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) m04gp34like PF12216.3 EMC78525.1 - 0.02 14.2 0.3 0.024 13.9 0.2 1.1 1 0 0 1 1 1 0 Immune evasion protein TMEM154 PF15102.1 EMC78525.1 - 0.028 14.1 0.2 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.15 EMC78525.1 - 0.031 13.9 0.7 0.047 13.3 0.5 1.2 1 0 0 1 1 1 0 Syndecan domain CbtB PF09489.5 EMC78525.1 - 0.035 13.9 0.9 0.06 13.2 0.6 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Adeno_E3_CR2 PF02439.10 EMC78525.1 - 0.036 13.6 2.5 0.053 13.0 1.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1705 PF08019.7 EMC78525.1 - 0.046 13.2 0.1 0.054 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) Shisa PF13908.1 EMC78525.1 - 0.063 13.4 0.5 0.074 13.2 0.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RseC_MucC PF04246.7 EMC78525.1 - 0.069 12.7 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Glycophorin_A PF01102.13 EMC78525.1 - 0.083 12.6 0.2 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycophorin A Herpes_gE PF02480.11 EMC78525.1 - 0.084 11.1 0.1 0.09 11.0 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.1 EMC78525.1 - 0.094 11.1 0.1 0.096 11.1 0.1 1.0 1 0 0 1 1 1 0 Amnionless S1FA PF04689.8 EMC78525.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA EphA2_TM PF14575.1 EMC78525.1 - 0.1 12.9 0.1 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PgaD PF13994.1 EMC78525.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein Calcipressin PF04847.7 EMC78526.1 - 1.9e-56 190.5 0.4 2.7e-56 190.1 0.3 1.2 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 EMC78526.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mg_trans_NIPA PF05653.9 EMC78527.1 - 3.5e-70 236.3 19.3 4.3e-70 236.0 13.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA CP2 PF04516.10 EMC78528.1 - 2.7e-80 268.8 0.1 3.9e-80 268.3 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tissue_fac PF01108.12 EMC78529.1 - 2.8e-22 78.4 0.0 4.6e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 EMC78529.1 - 7.4e-09 35.6 0.6 2.3e-08 34.0 0.2 2.0 2 1 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 EMC78529.1 - 0.0018 18.3 0.5 0.028 14.5 0.0 2.6 2 1 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC78529.1 - 0.0035 17.4 0.0 0.0084 16.2 0.0 1.7 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 EMC78530.1 - 4.1e-23 81.1 0.2 1.2e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 EMC78530.1 - 4.3e-07 29.9 0.1 1.1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III COP23 PF14218.1 EMC78530.1 - 0.018 14.5 0.2 0.046 13.2 0.1 1.6 1 0 0 1 1 1 0 Circadian oscillating protein COP23 fn3 PF00041.16 EMC78530.1 - 0.029 14.4 2.6 0.23 11.6 0.2 2.6 2 0 0 2 2 2 0 Fibronectin type III domain fn3 PF00041.16 EMC78531.1 - 1e-87 288.3 0.0 5.7e-19 68.0 0.0 6.1 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 EMC78531.1 - 2.4e-63 209.9 6.6 6.9e-18 64.2 0.2 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78531.1 - 5.6e-29 100.0 5.2 4.3e-06 26.7 0.0 7.3 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 EMC78531.1 - 5.1e-22 77.9 12.3 6.5e-06 26.0 0.1 8.9 8 2 0 8 8 8 4 Immunoglobulin V-set domain ig PF00047.20 EMC78531.1 - 1.8e-14 53.6 7.5 7.9e-05 22.6 0.0 7.0 8 0 0 8 8 8 3 Immunoglobulin domain Ig_3 PF13927.1 EMC78531.1 - 1.3e-08 35.2 0.3 0.47 10.9 0.0 5.2 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC78531.1 - 5.9e-08 32.5 0.1 0.032 14.1 0.0 4.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 EMC78531.1 - 1.3e-05 24.8 0.2 1.9 8.2 0.0 4.8 5 0 0 5 5 5 2 Tissue factor SusE PF14292.1 EMC78531.1 - 0.00058 19.6 0.0 0.59 9.9 0.0 4.8 5 1 0 5 5 5 1 SusE outer membrane protein Lipocalin_7 PF14651.1 EMC78532.1 - 2.4e-33 114.5 1.1 2.7e-33 114.4 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 EMC78532.1 - 3.3e-19 69.2 1.4 3.7e-19 69.1 1.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Toxin_58 PF15536.1 EMC78532.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 58 PNRC PF15365.1 EMC78533.1 - 1.8e-21 75.9 10.2 1.3e-20 73.0 2.1 2.3 2 0 0 2 2 2 2 Proline-rich nuclear receptor coactivator Ribosomal_S20p PF01649.13 EMC78533.1 - 0.0028 17.9 3.5 0.0048 17.2 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S20 Med25_SD1 PF11235.3 EMC78533.1 - 0.029 14.7 2.6 0.029 14.7 1.8 1.5 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 7tm_1 PF00001.16 EMC78534.1 - 2.3e-44 151.4 22.9 3.7e-44 150.8 15.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EMG1 PF03587.9 EMC78534.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase Alpha_L_fucos PF01120.12 EMC78535.1 - 4.8e-111 371.0 6.5 5.5e-111 370.8 4.5 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase HMGL-like PF00682.14 EMC78536.1 - 3.2e-73 246.2 0.1 3.7e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Terminase_2 PF03592.11 EMC78536.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Terminase small subunit Epimerase PF01370.16 EMC78537.1 - 2.3e-52 177.7 0.0 2.8e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMC78537.1 - 6e-30 102.9 0.5 1.7e-29 101.5 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EMC78537.1 - 4.3e-18 65.0 0.0 7.7e-17 60.8 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMC78537.1 - 1.4e-13 50.3 0.0 4.6e-13 48.6 0.0 1.7 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMC78537.1 - 2e-13 49.9 0.0 4.7e-11 42.1 0.0 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC78537.1 - 2.4e-11 43.9 0.0 7.4e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMC78537.1 - 2.5e-11 43.7 0.0 4.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMC78537.1 - 2.8e-10 39.5 0.0 1.2e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EMC78537.1 - 4.1e-06 26.5 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMC78537.1 - 0.0001 21.6 0.6 0.11 11.7 0.1 2.6 2 1 0 2 2 2 2 NmrA-like family Abhydrolase_2 PF02230.11 EMC78538.1 - 1.6e-77 259.7 0.0 1.8e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMC78538.1 - 1.6e-05 24.9 0.0 0.0068 16.3 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC78538.1 - 0.00096 18.9 0.3 0.0057 16.4 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC78538.1 - 0.016 14.4 0.0 0.048 12.8 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 EMC78538.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Collagen PF01391.13 EMC78539.1 - 4.2e-17 61.4 56.1 8.7e-10 38.0 19.5 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PITH PF06201.8 EMC78540.1 - 6.2e-35 120.2 0.0 7.6e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain 7tm_1 PF00001.16 EMC78541.1 - 8.5e-55 185.6 23.1 1.1e-54 185.3 16.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78541.1 - 0.0086 15.2 23.5 0.011 14.8 16.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MOZART2 PF12926.2 EMC78541.1 - 0.049 13.2 0.2 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF621 PF04789.10 EMC78541.1 - 0.24 10.3 24.2 0.46 9.4 16.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF621) HMG_box PF00505.14 EMC78542.1 - 2.9e-18 65.9 1.6 2.9e-18 65.9 1.1 2.5 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC78542.1 - 1.3e-06 28.6 0.6 1.3e-06 28.6 0.4 2.7 2 1 0 2 2 2 1 HMG-box domain Menin PF05053.8 EMC78542.1 - 7.4 4.6 20.3 12 3.8 14.1 1.2 1 0 0 1 1 1 0 Menin Filament PF00038.16 EMC78543.1 - 1.8e-107 359.4 21.7 2.2e-107 359.1 15.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC78543.1 - 0.0082 15.8 1.1 0.0082 15.8 0.8 4.1 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EMC78543.1 - 0.042 13.3 20.4 1.5 8.3 1.5 4.6 4 0 0 4 4 4 0 Septum formation initiator RasGAP_C PF03836.10 EMC78543.1 - 0.45 10.1 9.4 0.87 9.2 1.0 2.7 3 0 0 3 3 3 0 RasGAP C-terminus Prefoldin_2 PF01920.15 EMC78543.1 - 1.4 8.7 21.5 1.6 8.4 0.1 4.6 3 2 1 4 4 4 0 Prefoldin subunit FlaC_arch PF05377.6 EMC78543.1 - 1.5 8.7 4.6 7.5 6.5 0.2 3.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EMC78543.1 - 5.2 7.4 22.2 0.07 13.4 1.1 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF972) Filament PF00038.16 EMC78544.1 - 4.8e-22 78.8 17.2 6.7e-22 78.3 11.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein V_ATPase_I PF01496.14 EMC78544.1 - 0.013 13.3 4.4 0.016 13.0 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SYCE1 PF15233.1 EMC78544.1 - 0.046 13.6 13.1 0.096 12.6 9.1 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 FH2 PF02181.18 EMC78544.1 - 0.053 12.3 3.1 0.082 11.7 2.1 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain FUSC PF04632.7 EMC78544.1 - 0.058 11.8 3.2 0.067 11.6 2.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.7 EMC78544.1 - 0.058 13.1 2.2 0.36 10.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.1 EMC78544.1 - 0.19 11.1 12.5 0.29 10.5 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.7 EMC78544.1 - 0.49 10.1 10.2 0.15 11.7 3.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EMC78544.1 - 2.2 7.2 9.8 3.2 6.7 6.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EMC78544.1 - 2.4 7.6 12.4 5 6.6 8.6 1.5 1 0 0 1 1 1 0 IncA protein Filament PF00038.16 EMC78545.1 - 5.4e-106 354.5 43.2 8.8e-106 353.8 30.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 EMC78545.1 - 0.081 10.6 48.5 0.0035 15.1 7.8 3.0 1 1 2 3 3 3 0 Myosin tail WXG100 PF06013.7 EMC78545.1 - 1.8 8.6 16.4 0.28 11.2 0.5 3.9 5 0 0 5 5 5 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 EMC78545.1 - 2 8.2 27.7 0.65 9.7 4.6 4.5 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Ded_cyto PF06920.8 EMC78545.1 - 2 7.6 12.7 0.33 10.2 3.0 3.0 2 1 0 3 3 3 0 Dedicator of cytokinesis KfrA_N PF11740.3 EMC78545.1 - 3.4 8.1 23.5 0.96 9.9 6.0 3.2 1 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term YbjQ_1 PF01906.12 EMC78545.1 - 9 6.7 9.9 1.1 9.6 1.2 3.0 2 1 1 3 3 3 0 Putative heavy-metal-binding Filament PF00038.16 EMC78546.1 - 1.8e-85 287.1 35.8 2.3e-85 286.8 24.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein BRAP2 PF07576.7 EMC78546.1 - 0.1 12.1 2.9 0.11 12.0 0.1 2.4 3 0 0 3 3 3 0 BRCA1-associated protein 2 ADIP PF11559.3 EMC78546.1 - 0.16 11.9 28.2 0.74 9.7 7.4 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4296 PF14129.1 EMC78546.1 - 0.16 12.1 4.1 0.16 12.1 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4296) DUF3510 PF12022.3 EMC78546.1 - 0.32 11.0 6.0 0.12 12.4 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF4140 PF13600.1 EMC78546.1 - 2.9 8.3 17.4 3 8.3 0.9 4.5 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.4 EMC78546.1 - 3.7 7.4 32.0 0.49 10.2 4.7 4.2 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EMC78546.1 - 7.3 6.1 33.0 2.5 7.6 2.5 3.7 1 1 2 3 3 3 0 IncA protein Filament PF00038.16 EMC78547.1 - 2.9e-112 375.1 29.3 3.3e-112 375.0 20.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 EMC78547.1 - 3.8e-05 21.6 26.1 0.0022 15.8 5.5 2.4 2 0 0 2 2 2 2 Myosin tail Transposase_22 PF02994.9 EMC78547.1 - 0.002 16.6 16.2 0.0084 14.6 4.5 2.2 1 1 1 2 2 2 2 L1 transposable element Reo_sigmaC PF04582.7 EMC78547.1 - 0.0027 16.9 3.6 0.016 14.3 0.8 2.3 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF4618 PF15397.1 EMC78547.1 - 0.0041 16.5 6.9 0.0041 16.5 4.8 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 EMC78547.1 - 0.0051 16.6 9.3 3.6 7.3 2.0 3.6 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 EMC78547.1 - 0.0064 16.2 3.3 0.0064 16.2 2.3 3.4 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 EMC78547.1 - 0.011 15.6 13.5 0.33 10.8 0.1 4.5 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.1 EMC78547.1 - 0.018 13.9 11.3 0.096 11.6 2.6 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) BRE1 PF08647.6 EMC78547.1 - 0.036 14.0 0.7 0.036 14.0 0.5 4.1 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase DivIC PF04977.10 EMC78547.1 - 0.046 13.2 21.0 0.13 11.7 1.0 4.9 4 1 0 5 5 5 0 Septum formation initiator FlxA PF14282.1 EMC78547.1 - 0.048 13.6 11.7 0.63 10.0 2.2 3.2 3 1 0 3 3 3 0 FlxA-like protein CENP-F_leu_zip PF10473.4 EMC78547.1 - 0.08 12.7 31.1 0.078 12.8 1.4 4.9 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vac_Fusion PF02346.11 EMC78547.1 - 0.12 11.7 3.2 2.2 7.7 0.3 2.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF1664 PF07889.7 EMC78547.1 - 0.19 11.4 9.2 14 5.5 0.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 EMC78547.1 - 0.39 10.5 20.3 2.7 7.8 2.0 4.9 4 1 0 4 4 4 0 Prefoldin subunit Atg14 PF10186.4 EMC78547.1 - 0.53 9.1 16.2 0.14 11.1 6.7 2.7 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 EMC78547.1 - 0.69 9.0 23.1 0.39 9.8 2.8 3.1 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 EMC78547.1 - 0.83 10.0 19.7 12 6.3 0.2 5.0 4 1 1 5 5 5 0 SlyX bZIP_1 PF00170.16 EMC78547.1 - 1.1 9.2 16.4 0.47 10.4 1.3 4.7 4 0 0 4 4 4 0 bZIP transcription factor TMF_DNA_bd PF12329.3 EMC78547.1 - 1.5 8.6 20.3 8.1 6.3 0.7 4.7 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding HlyD PF00529.15 EMC78547.1 - 1.8 7.8 10.7 0.4 9.9 3.5 2.1 1 1 0 2 2 2 0 HlyD family secretion protein Fib_alpha PF08702.5 EMC78547.1 - 1.8 8.6 15.2 3 7.9 2.7 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Sipho_Gp157 PF05565.6 EMC78547.1 - 1.9 8.0 10.4 0.21 11.1 1.3 3.0 2 1 1 3 3 3 0 Siphovirus Gp157 EMP24_GP25L PF01105.19 EMC78547.1 - 2.2 7.9 7.6 3.8 7.1 0.4 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF148 PF02520.12 EMC78547.1 - 3.5 7.4 11.5 10 5.9 0.3 4.1 2 2 2 5 5 5 0 Domain of unknown function DUF148 ADIP PF11559.3 EMC78547.1 - 5.5 6.8 22.8 16 5.4 1.3 4.2 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 EMC78548.1 - 3.9e-24 85.6 6.7 4.2e-24 85.5 4.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein ParB PF08775.5 EMC78548.1 - 0.0092 16.2 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 1 ParB family Lebercilin PF15619.1 EMC78548.1 - 0.015 14.7 2.9 0.015 14.6 2.0 1.0 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.6 EMC78548.1 - 0.016 15.1 0.3 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.6 EMC78548.1 - 0.035 13.9 1.0 0.073 12.9 0.3 1.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cob_adeno_trans PF01923.13 EMC78548.1 - 0.038 13.7 0.5 0.041 13.6 0.4 1.0 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF2968 PF11180.3 EMC78548.1 - 0.065 12.6 2.8 0.067 12.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_27 PF13514.1 EMC78548.1 - 0.074 10.7 2.8 0.082 10.5 2.0 1.0 1 0 0 1 1 1 0 AAA domain DUF1019 PF06254.6 EMC78548.1 - 0.091 12.9 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) Baculo_PEP_C PF04513.7 EMC78548.1 - 0.096 12.5 0.5 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 EMC78548.1 - 0.1 12.0 0.6 0.15 11.5 0.4 1.2 1 0 0 1 1 1 0 Chordopoxvirus fusion protein cwf21 PF08312.7 EMC78548.1 - 0.64 9.9 3.1 2 8.3 2.2 1.9 1 1 0 1 1 1 0 cwf21 domain Filament PF00038.16 EMC78549.1 - 9.7e-48 163.2 23.1 1.1e-47 163.0 16.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Transposase_22 PF02994.9 EMC78549.1 - 1.9e-05 23.3 15.2 2.5e-05 22.9 10.6 1.0 1 0 0 1 1 1 1 L1 transposable element Transcrip_act PF04949.8 EMC78549.1 - 5.4e-05 22.8 6.0 0.0086 15.7 0.6 2.1 1 1 1 2 2 2 2 Transcriptional activator GAS PF13851.1 EMC78549.1 - 0.0005 19.3 20.3 0.0015 17.8 14.2 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EMC78549.1 - 0.0029 15.4 16.2 0.0048 14.6 11.2 1.4 1 0 0 1 1 1 1 Myosin tail Reo_sigmaC PF04582.7 EMC78549.1 - 0.0067 15.6 1.7 0.0085 15.3 1.2 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein WEMBL PF05701.6 EMC78549.1 - 0.0068 14.9 13.3 0.0089 14.5 9.2 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-Q PF13094.1 EMC78549.1 - 0.0075 16.3 16.7 0.0075 16.3 11.6 1.7 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Filo_VP35 PF02097.10 EMC78549.1 - 0.0085 15.3 2.5 0.0097 15.1 1.7 1.1 1 0 0 1 1 1 1 Filoviridae VP35 Baculo_PEP_C PF04513.7 EMC78549.1 - 0.0089 15.8 12.4 0.053 13.3 7.3 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EMC78549.1 - 0.01 15.6 10.9 0.091 12.6 3.5 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Ig_J_chain PF15097.1 EMC78549.1 - 0.014 15.0 0.9 0.019 14.5 0.6 1.2 1 0 0 1 1 1 0 Immunoglobulin J chain Tropomyosin_1 PF12718.2 EMC78549.1 - 0.015 15.1 18.1 0.057 13.2 10.5 2.2 1 1 1 2 2 2 0 Tropomyosin like IncA PF04156.9 EMC78549.1 - 0.02 14.4 27.6 0.027 14.0 18.1 1.7 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 EMC78549.1 - 0.024 13.2 20.5 0.02 13.5 9.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein RGCC PF15151.1 EMC78549.1 - 0.04 14.3 3.9 0.42 11.0 0.1 2.8 1 1 1 2 2 2 0 Response gene to complement 32 protein family DUF869 PF05911.6 EMC78549.1 - 0.049 11.8 12.9 0.058 11.6 8.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Atg14 PF10186.4 EMC78549.1 - 0.061 12.2 14.6 0.11 11.4 10.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nup88 PF10168.4 EMC78549.1 - 0.067 11.0 11.3 0.079 10.7 7.8 1.0 1 0 0 1 1 1 0 Nuclear pore component Phage_GP20 PF06810.6 EMC78549.1 - 0.084 12.3 14.3 0.024 14.0 7.4 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 Tho2 PF11262.3 EMC78549.1 - 0.11 11.5 9.3 0.16 10.9 5.9 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Cluap1 PF10234.4 EMC78549.1 - 0.13 11.4 13.6 0.19 10.8 9.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Fib_alpha PF08702.5 EMC78549.1 - 0.14 12.2 19.2 0.074 13.1 10.2 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 EMC78549.1 - 0.16 12.1 17.2 0.34 11.0 8.7 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lebercilin PF15619.1 EMC78549.1 - 0.16 11.3 21.1 0.22 10.9 14.6 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TACC PF05010.9 EMC78549.1 - 0.21 11.3 16.0 2.4 7.8 7.2 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Laminin_I PF06008.9 EMC78549.1 - 0.21 10.8 16.8 0.17 11.1 10.3 1.7 1 1 0 1 1 1 0 Laminin Domain I Kinetocho_Slk19 PF12709.2 EMC78549.1 - 0.26 11.3 14.7 0.95 9.5 0.6 2.9 1 1 0 2 2 2 0 Central kinetochore-associated Laminin_II PF06009.7 EMC78549.1 - 0.28 10.9 10.0 0.56 9.9 6.9 1.6 1 1 0 1 1 1 0 Laminin Domain II Orbi_VP5 PF00901.12 EMC78549.1 - 0.28 9.3 9.1 0.34 9.0 6.3 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Exonuc_VII_L PF02601.10 EMC78549.1 - 0.28 10.3 11.1 0.38 9.8 7.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF972 PF06156.8 EMC78549.1 - 0.3 11.4 18.0 0.44 10.9 0.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EMC78549.1 - 0.41 10.4 11.5 0.76 9.5 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EMC78549.1 - 0.46 8.8 14.6 1.3 7.4 10.2 1.4 1 1 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.6 EMC78549.1 - 0.54 9.5 13.1 4.6 6.5 7.5 2.7 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF603 PF04645.7 EMC78549.1 - 0.61 10.0 7.5 0.29 11.0 3.4 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF603 Phage_lysis PF03245.8 EMC78549.1 - 0.63 10.0 8.1 0.42 10.6 3.5 2.3 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein V_ATPase_I PF01496.14 EMC78549.1 - 0.68 7.7 14.0 0.43 8.3 8.3 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EMC78549.1 - 0.7 8.2 15.6 0.2 10.0 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) ADIP PF11559.3 EMC78549.1 - 0.71 9.7 22.6 0.22 11.4 11.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.5 EMC78549.1 - 0.86 9.8 23.9 3.8 7.7 5.1 3.6 1 1 2 3 3 3 0 Tup N-terminal FliD_C PF07195.7 EMC78549.1 - 0.89 8.8 10.8 1.1 8.5 6.5 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Lectin_N PF03954.9 EMC78549.1 - 0.97 8.8 7.6 2.4 7.5 3.5 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain HCMV_UL139 PF12507.3 EMC78549.1 - 1 9.5 6.3 3.9 7.6 0.4 2.4 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein DUF4140 PF13600.1 EMC78549.1 - 1.3 9.5 12.7 5.2 7.5 4.2 3.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) POX PF07526.6 EMC78549.1 - 1.5 9.0 9.7 1 9.5 5.5 1.6 1 1 0 1 1 1 0 Associated with HOX DUF3508 PF12018.3 EMC78549.1 - 1.8 7.4 13.9 0.98 8.3 8.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) NPV_P10 PF05531.7 EMC78549.1 - 1.9 8.7 10.1 5.2 7.3 6.2 2.3 1 1 2 3 3 2 0 Nucleopolyhedrovirus P10 protein V-ATPase_C PF03223.10 EMC78549.1 - 2.1 7.1 9.2 1.9 7.2 4.2 2.1 1 1 1 2 2 2 0 V-ATPase subunit C CENP-F_leu_zip PF10473.4 EMC78549.1 - 2.5 7.9 23.8 3 7.6 8.8 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T2SM PF04612.7 EMC78549.1 - 2.6 7.8 13.1 14 5.4 5.1 2.9 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M TBPIP PF07106.8 EMC78549.1 - 2.7 7.4 20.6 0.87 9.1 9.0 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EMC78549.1 - 3.4 7.4 23.4 5 6.8 4.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.6 EMC78549.1 - 3.6 7.4 14.1 14 5.5 1.5 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.3 EMC78549.1 - 4.1 6.5 16.8 4.9 6.3 11.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) WXG100 PF06013.7 EMC78549.1 - 4.3 7.3 14.1 3.5 7.6 4.5 3.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Tweety PF04906.8 EMC78549.1 - 5.2 5.3 8.0 5.2 5.3 4.8 1.6 1 1 0 1 1 1 0 Tweety DUF4200 PF13863.1 EMC78549.1 - 5.6 6.9 22.2 4.2 7.3 9.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.6 EMC78549.1 - 5.6 6.9 17.8 0.78 9.6 0.2 3.6 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF607 PF04678.8 EMC78549.1 - 5.7 6.8 7.5 36 4.2 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF607 APG6 PF04111.7 EMC78549.1 - 9.2 5.2 22.0 4.3 6.2 3.4 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 ACCA PF03255.9 EMC78549.1 - 9.2 5.8 8.4 6.4 6.3 3.4 2.3 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMPIT PF07851.8 EMC78549.1 - 9.4 5.1 15.6 8.7 5.3 2.1 1.9 1 1 1 2 2 2 0 TMPIT-like protein Uso1_p115_C PF04871.8 EMC78549.1 - 9.9 6.1 18.0 11 5.9 3.0 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 EMC78550.1 - 6.6e-74 249.1 34.5 1.3e-46 159.4 15.7 2.0 2 0 0 2 2 2 2 Intermediate filament protein Tropomyosin_1 PF12718.2 EMC78550.1 - 0.0008 19.2 22.5 0.028 14.2 9.6 3.3 2 2 0 2 2 2 2 Tropomyosin like ADIP PF11559.3 EMC78550.1 - 0.0017 18.3 13.3 0.0017 18.3 9.2 3.1 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding BAR_3_WASP_bdg PF10456.4 EMC78550.1 - 0.0024 17.1 2.4 0.079 12.2 0.1 2.3 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein Spc7 PF08317.6 EMC78550.1 - 0.0024 16.6 13.1 0.0024 16.6 9.1 2.8 2 1 1 3 3 3 1 Spc7 kinetochore protein CENP-Q PF13094.1 EMC78550.1 - 0.0028 17.7 12.8 0.0028 17.7 8.8 3.3 1 1 2 3 3 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Transposase_22 PF02994.9 EMC78550.1 - 0.0033 15.9 11.9 0.0033 15.9 8.2 1.8 2 0 0 2 2 2 1 L1 transposable element FlxA PF14282.1 EMC78550.1 - 0.0052 16.7 22.6 0.036 14.0 11.5 2.9 2 0 0 2 2 2 1 FlxA-like protein Transcrip_act PF04949.8 EMC78550.1 - 0.0095 15.5 10.2 0.091 12.3 0.3 2.7 2 1 1 3 3 3 2 Transcriptional activator IncA PF04156.9 EMC78550.1 - 0.011 15.2 34.9 0.061 12.9 16.4 3.0 2 1 1 3 3 3 0 IncA protein DUF2312 PF10073.4 EMC78550.1 - 0.022 14.1 0.1 0.022 14.1 0.1 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Lectin_N PF03954.9 EMC78550.1 - 0.079 12.3 9.1 0.62 9.4 0.7 3.1 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain Kinetocho_Slk19 PF12709.2 EMC78550.1 - 0.084 12.9 19.7 1.4 9.0 0.4 4.8 2 2 1 4 4 4 0 Central kinetochore-associated AAA_13 PF13166.1 EMC78550.1 - 0.1 11.0 17.8 0.53 8.6 12.0 2.1 1 1 0 1 1 1 0 AAA domain Laminin_II PF06009.7 EMC78550.1 - 0.1 12.3 12.4 0.073 12.8 4.5 2.5 2 1 0 2 2 2 0 Laminin Domain II APG6 PF04111.7 EMC78550.1 - 0.15 11.0 23.6 0.44 9.5 10.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4446 PF14584.1 EMC78550.1 - 0.21 11.4 17.5 0.83 9.4 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) WEMBL PF05701.6 EMC78550.1 - 0.26 9.7 20.4 0.012 14.0 9.9 1.7 2 0 0 2 2 2 0 Weak chloroplast movement under blue light HrpA_pilin PF09589.5 EMC78550.1 - 0.37 11.2 3.2 1 9.8 0.0 2.4 2 1 0 2 2 2 0 HrpA pilus formation protein DUF948 PF06103.6 EMC78550.1 - 0.73 9.7 6.4 22 5.0 0.5 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EMC78550.1 - 0.91 9.6 24.5 2 8.5 8.5 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EMC78550.1 - 1.3 8.8 30.1 15 5.3 0.0 4.3 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EMC78550.1 - 1.3 7.8 23.0 0.32 9.9 10.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EMC78550.1 - 1.6 6.5 13.6 2.3 5.9 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L29 PF00831.18 EMC78550.1 - 1.8 8.2 6.4 14 5.5 0.1 3.7 3 0 0 3 3 3 0 Ribosomal L29 protein DUF972 PF06156.8 EMC78550.1 - 2.9 8.3 27.1 9.9 6.5 0.7 4.9 2 2 3 5 5 5 0 Protein of unknown function (DUF972) XPG_I_2 PF12813.2 EMC78550.1 - 3 7.2 8.8 0.56 9.6 3.7 1.5 2 0 0 2 2 2 0 XPG domain containing TBPIP PF07106.8 EMC78550.1 - 3.3 7.2 25.2 0.076 12.5 7.5 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WXG100 PF06013.7 EMC78550.1 - 3.5 7.6 12.0 1.2 9.1 1.8 3.9 2 2 2 4 4 4 0 Proteins of 100 residues with WXG T2SM PF04612.7 EMC78550.1 - 3.6 7.3 12.7 7.7 6.2 0.0 3.2 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein M DUF1664 PF07889.7 EMC78550.1 - 4.4 7.1 12.2 1.3 8.8 2.7 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) POX PF07526.6 EMC78550.1 - 5.8 7.1 11.3 1.9 8.7 4.5 2.2 2 0 0 2 2 2 0 Associated with HOX FliD_C PF07195.7 EMC78550.1 - 6.9 5.8 12.0 47 3.1 8.3 2.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Tho2 PF11262.3 EMC78550.1 - 7 5.5 12.7 0.72 8.8 4.0 2.4 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HCMV_UL139 PF12507.3 EMC78550.1 - 7.3 6.7 11.1 8.2 6.6 1.4 2.6 2 1 1 3 3 2 0 Human Cytomegalovirus UL139 protein Phage_lysis PF03245.8 EMC78550.1 - 7.5 6.5 11.3 0.51 10.3 1.8 3.2 2 2 1 3 3 3 0 Bacteriophage Rz lysis protein DUF16 PF01519.11 EMC78550.1 - 8.3 6.6 16.3 0.51 10.5 3.7 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF4140 PF13600.1 EMC78550.1 - 8.6 6.8 18.5 8.5 6.8 1.6 4.4 2 2 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 EMC78550.1 - 9 4.5 23.0 4 5.7 5.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Orbi_VP5 PF00901.12 EMC78550.1 - 9.8 4.2 15.4 0.95 7.5 7.1 1.7 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 Filament PF00038.16 EMC78551.1 - 2.9e-100 335.7 34.8 3.3e-100 335.5 24.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC78551.1 - 6.9e-07 29.0 0.3 6.9e-07 29.0 0.2 3.7 3 1 1 4 4 4 3 TPR/MLP1/MLP2-like protein Transcrip_act PF04949.8 EMC78551.1 - 0.00021 20.9 7.7 0.042 13.4 0.9 2.7 2 1 1 3 3 3 2 Transcriptional activator WEMBL PF05701.6 EMC78551.1 - 0.00047 18.7 22.3 0.062 11.7 11.1 2.5 1 1 0 2 2 2 2 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 EMC78551.1 - 0.00061 19.6 29.6 0.0021 17.8 8.2 3.8 2 1 1 3 3 3 2 Tropomyosin like AAA_13 PF13166.1 EMC78551.1 - 0.0015 17.1 21.0 0.02 13.3 12.2 2.4 1 1 1 2 2 2 2 AAA domain Lectin_N PF03954.9 EMC78551.1 - 0.002 17.5 7.5 0.29 10.5 1.0 3.1 1 1 1 2 2 2 2 Hepatic lectin, N-terminal domain IncA PF04156.9 EMC78551.1 - 0.0025 17.4 37.8 0.0028 17.2 15.8 3.2 1 1 2 3 3 3 1 IncA protein Transposase_22 PF02994.9 EMC78551.1 - 0.0034 15.9 14.7 0.0034 15.9 10.2 2.7 1 1 2 3 3 3 1 L1 transposable element DUF2312 PF10073.4 EMC78551.1 - 0.017 14.4 1.0 0.098 12.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Laminin_II PF06009.7 EMC78551.1 - 0.017 14.8 16.2 0.038 13.7 5.0 3.2 2 1 1 3 3 3 0 Laminin Domain II V_ATPase_I PF01496.14 EMC78551.1 - 0.045 11.6 18.8 0.073 10.9 13.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 EMC78551.1 - 0.081 12.7 38.3 0.74 9.6 15.6 4.4 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 EMC78551.1 - 0.11 10.2 28.7 0.066 11.0 16.5 2.1 1 1 1 2 2 2 0 HOOK protein DUF342 PF03961.8 EMC78551.1 - 0.13 10.6 24.0 2.2 6.6 2.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DUF720 PF05302.6 EMC78551.1 - 0.23 11.2 11.2 0.049 13.3 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF720) DUF4200 PF13863.1 EMC78551.1 - 0.27 11.2 33.5 0.4 10.6 0.0 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4200) Vps5 PF09325.5 EMC78551.1 - 0.51 9.5 16.8 0.18 11.0 2.0 3.1 2 1 1 3 3 3 0 Vps5 C terminal like Filo_VP35 PF02097.10 EMC78551.1 - 0.52 9.4 3.7 1.2 8.2 1.5 2.1 2 0 0 2 2 2 0 Filoviridae VP35 Fib_alpha PF08702.5 EMC78551.1 - 0.54 10.3 26.2 1.5 8.9 10.0 3.8 2 2 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EMC78551.1 - 0.6 8.7 29.8 0.21 10.2 13.9 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein PspA_IM30 PF04012.7 EMC78551.1 - 0.89 8.8 25.0 1.6 8.0 0.6 4.3 2 1 2 4 4 4 0 PspA/IM30 family BLOC1_2 PF10046.4 EMC78551.1 - 0.96 9.6 25.9 0.45 10.6 7.1 4.8 4 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 EMC78551.1 - 1 9.2 35.2 0.22 11.4 10.4 4.4 2 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding Phage_Mu_Gam PF07352.7 EMC78551.1 - 1.1 8.7 20.4 3.3 7.2 2.4 4.3 3 1 1 4 4 4 0 Bacteriophage Mu Gam like protein FlxA PF14282.1 EMC78551.1 - 1.3 9.0 33.5 0.43 10.5 13.7 4.3 4 1 1 5 5 5 0 FlxA-like protein Kinetocho_Slk19 PF12709.2 EMC78551.1 - 1.4 9.0 28.4 0.49 10.5 2.9 5.5 5 1 1 6 6 6 0 Central kinetochore-associated DUF1664 PF07889.7 EMC78551.1 - 2.1 8.1 18.3 0.55 10.0 2.7 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EMC78551.1 - 2.2 7.1 23.6 0.12 11.2 10.1 2.6 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 EMC78551.1 - 2.5 7.2 8.3 6.1 5.9 1.9 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EMC78551.1 - 3.1 7.6 21.4 2.7 7.8 1.8 3.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4446 PF14584.1 EMC78551.1 - 3.7 7.3 21.1 2.3 8.0 3.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) DUF4407 PF14362.1 EMC78551.1 - 4.1 6.2 13.1 71 2.2 9.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.6 EMC78551.1 - 5.3 6.9 18.6 16 5.3 4.2 4.5 2 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.3 EMC78551.1 - 7.6 5.6 25.7 0.025 13.8 9.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) DASH_Dam1 PF08653.5 EMC78551.1 - 7.8 6.3 8.3 22 4.9 0.4 3.9 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF4140 PF13600.1 EMC78551.1 - 9.7 6.7 17.1 8.9 6.8 1.5 4.6 2 1 2 5 5 4 0 N-terminal domain of unknown function (DUF4140) Filament PF00038.16 EMC78552.1 - 1.1e-97 327.3 41.3 1.2e-97 327.1 28.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.1 EMC78552.1 - 0.0009 18.4 37.4 0.062 12.4 11.9 4.2 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EMC78552.1 - 0.0011 18.6 3.9 0.0011 18.6 2.7 4.0 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EMC78552.1 - 0.0023 17.8 13.3 0.0023 17.8 9.2 4.1 2 2 2 4 4 4 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EMC78552.1 - 0.003 16.2 13.0 0.003 16.2 9.0 3.5 1 1 2 4 4 4 1 Spc7 kinetochore protein CENP-Q PF13094.1 EMC78552.1 - 0.0039 17.2 13.3 0.0039 17.2 9.2 4.1 1 1 2 3 3 2 1 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EMC78552.1 - 0.009 15.6 20.9 0.009 15.6 14.5 3.4 1 1 1 3 3 3 1 IncA protein Lectin_N PF03954.9 EMC78552.1 - 0.014 14.7 11.6 0.69 9.3 0.9 3.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF4200 PF13863.1 EMC78552.1 - 0.015 15.2 0.1 0.015 15.2 0.1 4.6 3 2 1 4 4 4 0 Domain of unknown function (DUF4200) WEMBL PF05701.6 EMC78552.1 - 0.035 12.5 29.8 0.85 8.0 0.3 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Death PF00531.17 EMC78552.1 - 0.039 13.7 0.2 0.039 13.7 0.1 3.2 3 0 0 3 3 2 0 Death domain Myosin_tail_1 PF01576.14 EMC78552.1 - 0.046 11.4 37.4 0.048 11.3 7.2 2.7 1 1 1 2 2 2 0 Myosin tail Tropomyosin_1 PF12718.2 EMC78552.1 - 0.057 13.2 35.9 0.063 13.1 10.1 4.2 1 1 2 3 3 3 0 Tropomyosin like CENP-F_leu_zip PF10473.4 EMC78552.1 - 0.091 12.6 45.3 0.2 11.5 5.4 4.7 1 1 3 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dam1 PF08653.5 EMC78552.1 - 0.23 11.2 9.1 13 5.6 0.4 4.1 3 1 0 3 3 3 0 DASH complex subunit Dam1 Kinetocho_Slk19 PF12709.2 EMC78552.1 - 0.26 11.3 28.6 2.8 8.0 0.4 5.8 3 2 1 5 5 5 0 Central kinetochore-associated AAA_13 PF13166.1 EMC78552.1 - 0.29 9.5 24.0 0.97 7.8 14.5 2.4 1 1 1 2 2 2 0 AAA domain HXXSHH PF07586.6 EMC78552.1 - 0.3 9.9 4.3 0.068 12.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) FlxA PF14282.1 EMC78552.1 - 0.99 9.3 34.7 0.038 13.9 11.3 4.3 2 1 2 4 4 4 0 FlxA-like protein Transposase_22 PF02994.9 EMC78552.1 - 1.5 7.2 27.9 0.035 12.5 10.9 2.5 1 1 0 2 2 2 0 L1 transposable element WXG100 PF06013.7 EMC78552.1 - 2 8.4 11.4 1.7 8.7 2.1 4.1 2 2 2 4 4 4 0 Proteins of 100 residues with WXG Laminin_II PF06009.7 EMC78552.1 - 2.6 7.8 20.7 0.22 11.2 4.7 3.4 2 1 1 3 3 3 0 Laminin Domain II DUF641 PF04859.7 EMC78552.1 - 2.9 7.6 23.1 4.6 6.9 0.1 4.4 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) MAD PF05557.8 EMC78552.1 - 3.1 5.7 38.5 3 5.8 2.3 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Atg14 PF10186.4 EMC78552.1 - 3.7 6.4 29.2 0.39 9.6 10.4 2.9 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 XPG_I_2 PF12813.2 EMC78552.1 - 4.7 6.6 9.8 0.81 9.1 3.7 1.8 2 0 0 2 2 2 0 XPG domain containing Fib_alpha PF08702.5 EMC78552.1 - 5.1 7.2 28.5 10 6.2 0.2 3.9 2 2 0 3 3 3 0 Fibrinogen alpha/beta chain family T2SM PF04612.7 EMC78552.1 - 6.8 6.4 13.7 6.4 6.5 0.0 3.3 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein M DUF342 PF03961.8 EMC78552.1 - 6.9 4.9 29.0 1.7 6.9 0.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Filament PF00038.16 EMC78553.1 - 6e-103 344.5 26.7 6.7e-103 344.4 18.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC78553.1 - 2.3e-06 27.4 0.8 2.3e-06 27.4 0.6 3.6 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EMC78553.1 - 0.00011 22.0 32.6 0.00066 19.5 3.8 4.9 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kinetocho_Slk19 PF12709.2 EMC78553.1 - 0.00034 20.6 13.7 0.055 13.5 0.5 4.6 4 1 1 5 5 5 2 Central kinetochore-associated Nsp1_C PF05064.8 EMC78553.1 - 0.0005 19.6 6.2 0.0005 19.6 4.3 3.6 2 2 1 3 3 3 1 Nsp1-like C-terminal region TBPIP PF07106.8 EMC78553.1 - 0.0094 15.5 7.8 0.0094 15.5 5.4 3.2 2 1 0 3 3 3 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 EMC78553.1 - 0.01 15.7 0.4 0.01 15.7 0.2 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EMC78553.1 - 0.01 13.7 10.7 0.013 13.3 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 EMC78553.1 - 0.023 14.5 27.4 0.2 11.5 0.7 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 EMC78553.1 - 0.039 13.7 15.8 0.17 11.7 5.3 3.5 2 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EMC78553.1 - 0.053 13.3 22.5 0.43 10.4 7.1 3.5 3 1 0 3 3 3 0 Tropomyosin like IFT57 PF10498.4 EMC78553.1 - 0.18 10.5 19.1 0.46 9.1 6.5 2.9 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Transposase_22 PF02994.9 EMC78553.1 - 0.19 10.2 20.2 0.026 13.0 7.3 2.4 2 1 0 2 2 2 0 L1 transposable element Bacillus_HBL PF05791.6 EMC78553.1 - 0.26 10.6 8.8 0.78 9.0 2.1 3.0 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Myosin_tail_1 PF01576.14 EMC78553.1 - 0.28 8.8 26.9 0.38 8.4 2.3 2.8 2 2 0 3 3 3 0 Myosin tail DUF1664 PF07889.7 EMC78553.1 - 0.33 10.7 10.8 0.46 10.3 0.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 EMC78553.1 - 0.42 11.0 15.3 6.1 7.3 1.1 4.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) MscS_porin PF12795.2 EMC78553.1 - 0.63 9.3 21.6 0.86 8.8 10.1 3.2 3 1 0 3 3 2 0 Mechanosensitive ion channel porin domain HR1 PF02185.11 EMC78553.1 - 0.68 9.7 16.7 2 8.2 0.7 4.1 2 1 1 3 3 3 0 Hr1 repeat FlaC_arch PF05377.6 EMC78553.1 - 0.85 9.5 16.4 0.28 11.1 0.2 4.9 4 1 0 5 5 4 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EMC78553.1 - 1.3 8.5 38.2 1.5 8.4 14.8 3.4 1 1 2 3 3 3 0 IncA protein DUF745 PF05335.8 EMC78553.1 - 1.6 8.2 10.0 1.1 8.7 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Alpha_E2_glycop PF00943.14 EMC78553.1 - 1.6 7.2 9.6 0.14 10.7 2.6 1.8 1 1 1 2 2 2 0 Alphavirus E2 glycoprotein Spc7 PF08317.6 EMC78553.1 - 1.7 7.2 24.6 0.017 13.8 3.7 3.5 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF948 PF06103.6 EMC78553.1 - 2.1 8.2 8.0 5.3 6.9 0.6 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EMC78553.1 - 2.7 7.8 18.0 8.5 6.2 0.0 4.5 4 1 1 5 5 4 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EMC78553.1 - 5.3 7.0 23.9 0.93 9.4 8.2 4.0 2 2 0 3 3 3 0 FlxA-like protein Prefoldin_2 PF01920.15 EMC78553.1 - 7.9 6.3 27.3 2.5 7.9 1.6 5.1 4 1 1 5 5 4 0 Prefoldin subunit DivIC PF04977.10 EMC78553.1 - 9.4 5.8 26.1 3.6 7.1 0.2 5.3 4 1 2 6 6 6 0 Septum formation initiator Filament PF00038.16 EMC78554.1 - 1.8e-107 359.4 24.3 2.1e-107 359.2 16.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC78554.1 - 1.7e-05 24.5 23.5 2.4e-05 24.0 0.6 3.0 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EMC78554.1 - 0.00031 20.6 32.1 0.014 15.2 9.0 4.9 3 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EMC78554.1 - 0.00037 18.3 21.8 0.00095 17.0 6.4 2.2 2 1 0 2 2 2 2 Myosin tail Nsp1_C PF05064.8 EMC78554.1 - 0.0011 18.6 6.2 0.0011 18.6 4.3 3.2 2 2 1 3 3 3 1 Nsp1-like C-terminal region Kinetocho_Slk19 PF12709.2 EMC78554.1 - 0.0015 18.5 13.8 0.41 10.7 0.5 4.5 4 1 1 5 5 5 2 Central kinetochore-associated Baculo_PEP_C PF04513.7 EMC78554.1 - 0.0038 17.0 6.6 0.0075 16.0 0.3 2.8 3 0 0 3 3 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EMC78554.1 - 0.025 14.4 20.9 1.1 9.0 7.6 3.4 3 0 0 3 3 3 0 Tropomyosin like DUF234 PF03008.9 EMC78554.1 - 0.042 13.9 0.9 0.12 12.5 0.6 1.7 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Prefoldin_2 PF01920.15 EMC78554.1 - 0.044 13.5 22.8 1.7 8.4 1.5 5.0 5 1 0 5 5 4 0 Prefoldin subunit DUF4200 PF13863.1 EMC78554.1 - 0.055 13.4 0.5 0.055 13.4 0.4 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) MADF_DNA_bdg PF10545.4 EMC78554.1 - 0.099 12.8 3.4 0.54 10.4 0.1 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4140 PF13600.1 EMC78554.1 - 0.13 12.7 12.2 14 6.2 0.7 4.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Bacillus_HBL PF05791.6 EMC78554.1 - 0.25 10.7 7.9 0.55 9.5 1.4 2.8 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EMC78554.1 - 0.33 10.5 35.4 0.17 11.5 13.3 3.5 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 EMC78554.1 - 0.34 10.4 20.6 0.021 14.3 5.0 3.1 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HR1 PF02185.11 EMC78554.1 - 0.42 10.3 18.2 2.5 7.9 0.7 4.0 3 1 1 4 4 3 0 Hr1 repeat ADIP PF11559.3 EMC78554.1 - 0.46 10.3 27.7 0.38 10.6 1.3 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.12 EMC78554.1 - 0.6 9.7 11.1 3.4 7.3 0.3 3.9 2 1 0 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 EMC78554.1 - 0.77 9.9 16.2 0.41 10.8 2.0 4.3 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 EMC78554.1 - 0.87 10.0 19.8 1.6 9.1 1.9 4.4 3 1 1 4 4 4 0 SlyX TMF_DNA_bd PF12329.3 EMC78554.1 - 0.9 9.3 15.8 0.064 13.0 2.2 3.8 4 0 0 4 4 3 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EMC78554.1 - 1.7 8.6 21.5 0.36 10.8 6.9 3.9 2 2 1 3 3 3 0 FlxA-like protein MscS_porin PF12795.2 EMC78554.1 - 1.9 7.7 18.6 2.5 7.3 2.8 3.6 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain DivIC PF04977.10 EMC78554.1 - 1.9 8.0 20.2 4.4 6.8 0.2 5.0 5 0 0 5 5 5 0 Septum formation initiator BRE1 PF08647.6 EMC78554.1 - 2 8.4 10.8 1.2 9.1 0.2 3.4 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.6 EMC78554.1 - 2.4 8.1 15.0 0.87 9.5 0.0 4.7 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 EMC78554.1 - 2.8 7.8 6.4 6.7 6.6 0.6 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Phage_GPO PF05929.6 EMC78554.1 - 3.4 6.8 8.5 1.5 8.0 1.9 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cortex-I_coil PF09304.5 EMC78554.1 - 5 7.2 23.3 2 8.5 5.7 3.7 1 1 2 4 4 4 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EMC78554.1 - 5.1 4.8 12.6 8.5 4.0 8.7 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EMC78554.1 - 5.3 5.6 21.9 0.41 9.2 6.1 3.2 1 1 4 5 5 5 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 EMC78554.1 - 5.6 6.3 13.6 5 6.5 4.3 3.4 1 1 0 2 2 2 0 Phage minor structural protein GP20 Transposase_22 PF02994.9 EMC78554.1 - 6.3 5.1 17.3 2.9 6.3 7.0 2.1 2 0 0 2 2 2 0 L1 transposable element DUF1664 PF07889.7 EMC78554.1 - 8 6.2 10.6 1.6 8.5 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.16 EMC78555.1 - 1.1e-23 84.2 5.5 1.1e-23 84.1 3.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein Lipoprotein_20 PF13942.1 EMC78555.1 - 0.017 14.6 0.8 0.018 14.5 0.5 1.0 1 0 0 1 1 1 0 YfhG lipoprotein BRE1 PF08647.6 EMC78555.1 - 0.018 15.0 1.3 0.029 14.3 0.7 1.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Kinetocho_Slk19 PF12709.2 EMC78555.1 - 0.019 15.0 0.7 0.027 14.5 0.5 1.3 1 0 0 1 1 1 0 Central kinetochore-associated Cortex-I_coil PF09304.5 EMC78555.1 - 0.031 14.3 0.5 0.044 13.8 0.4 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4600 PF15372.1 EMC78555.1 - 0.04 14.1 2.3 1.2 9.3 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) Occludin_ELL PF07303.8 EMC78555.1 - 0.05 14.3 1.6 0.062 14.0 1.1 1.2 1 0 0 1 1 1 0 Occludin homology domain FlxA PF14282.1 EMC78555.1 - 0.066 13.1 2.1 0.066 13.1 0.6 1.3 1 1 0 1 1 1 0 FlxA-like protein YlqD PF11068.3 EMC78555.1 - 0.11 12.5 2.1 0.12 12.3 1.4 1.1 1 0 0 1 1 1 0 YlqD protein LemA PF04011.7 EMC78555.1 - 0.13 11.3 0.4 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 LemA family FlaC_arch PF05377.6 EMC78555.1 - 0.14 12.0 0.5 0.3 11.0 0.0 1.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EMC78555.1 - 0.31 10.8 5.2 0.94 9.3 1.6 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EMC78555.1 - 0.63 9.6 5.7 0.75 9.3 4.0 1.1 1 0 0 1 1 1 0 IncA protein HR1 PF02185.11 EMC78555.1 - 0.81 9.4 4.2 0.58 9.9 1.3 1.8 2 0 0 2 2 2 0 Hr1 repeat DUF3498 PF12004.3 EMC78555.1 - 2.6 7.0 6.0 3 6.8 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Nsp1_C PF05064.8 EMC78555.1 - 2.6 7.6 5.1 3.5 7.2 0.2 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region Sugarporin_N PF11471.3 EMC78555.1 - 3.2 7.4 9.5 7.2 6.3 0.2 2.5 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension Filament PF00038.16 EMC78556.1 - 2.5e-72 243.9 8.0 2.8e-72 243.8 5.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein MADF_DNA_bdg PF10545.4 EMC78556.1 - 0.0047 17.0 0.9 0.023 14.9 0.2 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Spc7 PF08317.6 EMC78556.1 - 0.077 11.6 10.8 0.024 13.3 3.0 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein Kinetocho_Slk19 PF12709.2 EMC78556.1 - 0.11 12.6 6.7 0.46 10.5 0.5 3.4 4 0 0 4 4 4 0 Central kinetochore-associated TPR_MLP1_2 PF07926.7 EMC78556.1 - 0.31 10.7 12.7 0.55 9.9 0.1 2.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3019 PF11456.3 EMC78556.1 - 0.67 10.2 9.3 0.062 13.6 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3019) CENP-F_leu_zip PF10473.4 EMC78556.1 - 1.1 9.1 16.7 3.4 7.5 3.2 3.6 3 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rho_Binding PF08912.6 EMC78556.1 - 2.5 8.4 8.5 7.1 7.0 2.0 3.6 3 1 0 3 3 3 0 Rho Binding Tropomyosin_1 PF12718.2 EMC78556.1 - 3.4 7.5 11.2 4.9 7.0 2.7 2.8 2 1 1 3 3 3 0 Tropomyosin like DUF4200 PF13863.1 EMC78556.1 - 4.2 7.3 13.1 5.3 6.9 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 EMC78557.1 - 1.1e-108 363.4 27.7 6.3e-108 360.9 19.2 1.9 1 1 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 EMC78557.1 - 0.0003 18.7 6.2 0.0003 18.7 4.3 2.4 2 1 0 2 2 2 2 Myosin tail DUF2773 PF10971.3 EMC78557.1 - 0.034 14.1 0.8 0.2 11.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) DUF2248 PF10005.4 EMC78557.1 - 0.046 12.6 0.4 0.079 11.8 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) DUF4618 PF15397.1 EMC78557.1 - 0.39 9.9 13.1 0.022 14.1 3.7 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) Bacillus_HBL PF05791.6 EMC78557.1 - 0.6 9.4 8.8 0.67 9.3 2.0 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4510 PF14971.1 EMC78557.1 - 0.62 10.2 8.1 0.5 10.5 1.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) HR1 PF02185.11 EMC78557.1 - 1.2 8.9 13.2 0.38 10.5 0.5 4.0 2 1 1 3 3 3 0 Hr1 repeat FlxA PF14282.1 EMC78557.1 - 2 8.4 16.8 1.6 8.7 3.9 3.5 3 1 1 4 4 4 0 FlxA-like protein Atg14 PF10186.4 EMC78557.1 - 2.5 6.9 18.5 1.8 7.4 5.2 2.9 1 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 WXG100 PF06013.7 EMC78557.1 - 3.4 7.7 9.5 2.1 8.4 0.5 3.6 2 1 2 4 4 3 0 Proteins of 100 residues with WXG ADIP PF11559.3 EMC78557.1 - 4.3 7.2 24.4 2.4 8.0 0.4 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EMC78557.1 - 5.5 6.5 24.3 0.5 9.8 0.9 4.9 6 0 0 6 6 5 0 Septum formation initiator DUF972 PF06156.8 EMC78557.1 - 8.1 6.8 24.0 8.1 6.8 0.1 5.3 2 2 3 5 5 5 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 EMC78557.1 - 8.6 6.3 12.6 10 6.1 0.0 4.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EMC78557.1 - 9.1 6.0 14.0 1.8 8.3 0.5 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) SUI1 PF01253.17 EMC78558.1 - 6.9e-30 102.6 1.3 7.9e-30 102.5 0.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mitoc_L55 PF09776.4 EMC78558.1 - 0.12 11.9 0.1 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Milton PF12448.3 EMC78559.1 - 0.00059 20.0 0.0 0.00081 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin associated protein Arm PF00514.18 EMC78560.1 - 1.7e-53 176.7 22.0 5e-10 38.8 0.0 11.6 12 0 0 12 12 12 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC78560.1 - 3.2e-16 59.3 12.7 2.7e-06 27.5 0.9 5.6 4 1 1 5 5 5 5 HEAT repeats HEAT PF02985.17 EMC78560.1 - 1.5e-11 43.3 5.2 0.034 14.2 0.0 7.0 6 0 0 6 6 6 3 HEAT repeat V-ATPase_H_N PF03224.9 EMC78560.1 - 9.5e-07 28.2 0.8 0.048 12.7 0.1 3.3 2 1 1 3 3 3 3 V-ATPase subunit H Adaptin_N PF01602.15 EMC78560.1 - 1.8e-06 26.6 6.4 0.00045 18.6 0.4 2.8 2 1 0 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 EMC78560.1 - 5.3e-05 21.6 6.3 0.0033 15.7 1.0 2.6 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit RIX1 PF08167.7 EMC78560.1 - 8.6e-05 22.2 3.4 0.24 11.0 0.1 2.9 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis Arm_2 PF04826.8 EMC78560.1 - 0.00011 21.4 2.7 0.38 9.8 0.1 4.5 3 2 2 5 5 5 1 Armadillo-like HEAT_EZ PF13513.1 EMC78560.1 - 0.0015 18.9 12.4 2.1 8.9 0.1 6.6 6 2 1 7 7 6 2 HEAT-like repeat RasGEF_N_2 PF14663.1 EMC78560.1 - 0.016 15.1 8.1 13 5.8 0.0 5.2 5 1 2 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Atx10homo_assoc PF09759.4 EMC78560.1 - 0.038 13.7 1.4 0.39 10.4 0.0 3.2 4 1 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.2 EMC78560.1 - 0.16 11.7 3.9 0.39 10.5 0.1 3.1 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 UMPH-1 PF05822.7 EMC78561.1 - 1.7e-119 397.6 0.4 2e-119 397.4 0.3 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 EMC78561.1 - 4.9e-05 23.5 0.0 7.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMC78561.1 - 0.01 15.0 0.5 0.059 12.5 0.1 2.2 2 1 0 2 2 2 0 Putative Phosphatase HAD_2 PF13419.1 EMC78561.1 - 0.016 15.4 0.0 0.039 14.1 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Kelch_1 PF01344.20 EMC78562.1 - 5.3e-72 237.1 15.9 2.2e-15 55.8 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC78562.1 - 5.8e-47 156.0 10.0 3.8e-10 39.4 0.0 6.4 2 1 4 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EMC78562.1 - 5.3e-31 105.1 2.8 5.3e-05 22.8 0.0 6.9 7 0 0 7 7 7 6 Kelch motif BACK PF07707.10 EMC78562.1 - 7.7e-31 105.9 0.3 1.4e-30 105.1 0.2 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 EMC78562.1 - 3e-29 101.2 0.2 9.7e-29 99.6 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 EMC78562.1 - 8.7e-27 92.6 9.5 6.5e-06 26.1 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC78562.1 - 1.1e-25 89.1 6.4 0.00016 21.3 0.0 5.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC78562.1 - 2e-16 59.5 13.9 0.0048 16.8 0.3 6.5 6 0 0 6 6 6 6 Kelch motif TAN PF11640.3 EMC78562.1 - 0.16 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair BCS1_N PF08740.6 EMC78562.1 - 0.2 11.2 0.7 1.3 8.5 0.0 2.5 3 0 0 3 3 3 0 BCS1 N terminal TPR_12 PF13424.1 EMC78563.1 - 1.6e-13 50.4 3.5 7.9e-07 28.9 0.7 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC78563.1 - 1.4e-09 37.4 1.9 0.0001 21.8 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 EMC78563.1 - 2.3e-09 36.3 3.5 0.011 15.4 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC78563.1 - 5.1e-08 32.1 6.5 0.28 11.0 0.1 5.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC78563.1 - 9e-08 31.4 5.8 0.13 11.9 0.2 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC78563.1 - 1.1e-07 31.1 5.1 0.047 13.6 0.0 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC78563.1 - 0.0011 18.8 0.5 0.056 13.3 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC78563.1 - 0.0013 18.8 0.6 0.49 10.5 0.0 2.6 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC78563.1 - 0.0035 17.6 9.8 3.6 8.2 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat RPN7 PF10602.4 EMC78563.1 - 0.017 14.4 0.2 0.078 12.3 0.1 1.9 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DDE_Tnp_1_3 PF13612.1 EMC78563.1 - 0.098 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Transposase DDE domain TPR_16 PF13432.1 EMC78563.1 - 0.1 13.3 6.8 0.6 10.8 0.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78563.1 - 0.19 12.4 2.6 6.1 7.7 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC78564.1 - 1.4e-51 172.0 26.2 1.5e-18 66.1 2.6 6.3 2 1 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 EMC78564.1 - 1.5e-42 141.5 28.8 1.4e-06 27.6 0.0 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMC78564.1 - 1.1e-40 134.2 21.9 4.9e-06 26.0 1.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.26 EMC78564.1 - 9.2e-25 86.1 2.6 9.2e-25 86.1 1.8 3.0 3 0 0 3 3 2 1 DnaJ domain TPR_16 PF13432.1 EMC78564.1 - 1e-19 70.6 9.0 1.3e-05 25.7 0.6 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC78564.1 - 1.9e-19 67.8 16.5 0.00063 19.3 1.6 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC78564.1 - 1.4e-16 60.5 14.4 0.0045 17.2 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMC78564.1 - 1.5e-16 59.1 13.1 6.6e-05 22.8 0.1 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC78564.1 - 7.8e-16 57.7 21.6 0.00016 21.5 0.3 6.7 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78564.1 - 3.3e-13 48.9 7.2 0.048 14.3 0.0 8.0 6 3 3 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC78564.1 - 1.3e-10 41.0 11.4 0.29 11.0 0.1 6.2 3 3 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC78564.1 - 1.4e-10 41.1 26.5 0.0001 22.3 0.2 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC78564.1 - 9.1e-08 32.0 11.8 0.22 12.0 0.5 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC78564.1 - 1.3e-07 30.8 9.8 0.45 10.4 0.3 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMC78564.1 - 0.0032 17.7 0.4 1.6 9.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EMC78564.1 - 0.0069 16.2 16.1 0.23 11.3 0.5 5.1 3 2 0 3 3 3 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EMC78564.1 - 0.049 13.5 11.1 17 5.3 0.1 5.9 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EMC78564.1 - 0.069 13.1 10.3 21 5.1 0.3 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EMC78564.1 - 0.49 10.6 11.1 7.1 6.8 0.1 4.6 4 1 1 5 5 5 0 Alkyl sulfatase dimerisation TOM20_plant PF06552.7 EMC78564.1 - 1 8.9 8.0 7.2 6.1 0.1 3.6 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.4 EMC78564.1 - 5 6.4 9.9 5.9 6.2 0.1 5.2 6 0 0 6 6 6 0 SHNi-TPR Ras PF00071.17 EMC78565.1 - 3.3e-26 91.6 0.4 3.8e-26 91.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC78565.1 - 5.3e-20 72.0 0.3 9.2e-20 71.3 0.2 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC78565.1 - 3.2e-08 32.9 0.1 4.1e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC78565.1 - 1.5e-06 27.7 0.1 5.2e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC78565.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC78565.1 - 0.00018 21.3 0.9 0.00049 19.9 0.6 1.9 1 1 0 1 1 1 1 Dynamin family G-alpha PF00503.15 EMC78565.1 - 0.0035 16.0 0.2 0.035 12.7 0.2 1.8 1 1 0 1 1 1 1 G-protein alpha subunit DUF2121 PF09894.4 EMC78565.1 - 0.0036 16.6 0.1 0.057 12.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) SpoIIP PF07454.6 EMC78565.1 - 0.051 12.7 0.1 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SRPRB PF09439.5 EMC78565.1 - 0.096 11.9 0.6 0.32 10.2 0.4 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EMC78565.1 - 0.11 13.2 0.2 0.2 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EMC78565.1 - 0.14 11.3 0.7 0.24 10.4 0.5 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region LRAT PF04970.8 EMC78567.1 - 2.5e-05 24.2 4.0 0.011 15.7 0.1 2.1 1 1 1 2 2 2 2 Lecithin retinol acyltransferase DUF830 PF05708.7 EMC78567.1 - 0.055 13.4 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) NLPC_P60 PF00877.14 EMC78567.1 - 0.096 12.5 0.1 0.27 11.0 0.0 1.8 1 1 0 1 1 1 0 NlpC/P60 family Calici_PP_N PF08405.6 EMC78567.1 - 0.12 11.2 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal zf-C4 PF00105.13 EMC78568.1 - 3.5e-28 97.6 14.1 4e-28 97.4 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC78568.1 - 1.1e-27 96.5 0.2 3.2e-27 94.9 0.2 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Peptidase_C48 PF02902.14 EMC78569.1 - 9.6e-13 48.2 0.3 5e-12 45.9 0.2 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PK_C PF02887.11 EMC78570.1 - 3.2e-30 104.0 0.0 4.1e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Biotin_lipoyl PF00364.17 EMC78571.1 - 3e-21 74.8 2.6 3.4e-21 74.6 1.8 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMC78571.1 - 9.7e-12 44.3 0.1 1.2e-06 28.0 0.0 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EMC78571.1 - 1.8e-05 25.0 0.1 0.0067 16.7 0.0 2.0 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 EMC78571.1 - 0.00064 18.9 0.0 0.0082 15.3 0.0 1.9 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 EMC78571.1 - 0.001 18.7 2.0 0.0021 17.7 1.4 1.6 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 EMC78571.1 - 0.002 17.4 0.1 0.63 9.2 0.0 2.0 1 1 1 2 2 2 2 HlyD family secretion protein PYNP_C PF07831.8 EMC78571.1 - 0.0038 16.6 0.1 2.2 7.7 0.0 2.1 1 1 0 2 2 2 2 Pyrimidine nucleoside phosphorylase C-terminal domain PASTA PF03793.14 EMC78571.1 - 0.0044 16.6 0.1 0.07 12.7 0.0 2.1 2 0 0 2 2 2 1 PASTA domain GCV_H PF01597.14 EMC78571.1 - 0.0071 16.0 0.2 0.0085 15.7 0.2 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Peptidase_M23 PF01551.17 EMC78571.1 - 0.028 14.4 0.2 0.6 10.1 0.0 2.2 1 1 0 1 1 1 0 Peptidase family M23 GTP_EFTU_D4 PF14578.1 EMC78571.1 - 0.069 12.7 0.3 0.081 12.5 0.2 1.1 1 0 0 1 1 1 0 Elongation factor Tu domain 4 NQRA PF05896.6 EMC78571.1 - 0.079 12.1 0.5 0.11 11.6 0.2 1.3 1 1 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PTS_EIIA_1 PF00358.15 EMC78571.1 - 0.12 11.9 0.1 7.6 6.1 0.0 2.2 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 AIG2 PF06094.7 EMC78572.1 - 4.9e-19 68.7 0.1 6.2e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family TPR_11 PF13414.1 EMC78573.1 - 3e-43 145.3 38.7 3e-12 46.0 0.4 5.6 1 1 6 7 7 7 7 TPR repeat TPR_1 PF00515.23 EMC78573.1 - 1.4e-34 116.2 19.1 4.6e-05 22.8 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat DUF1736 PF08409.6 EMC78573.1 - 1.6e-32 110.9 2.3 3.3e-32 109.8 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.12 EMC78573.1 - 2.5e-29 98.8 17.0 9.2e-06 25.1 0.2 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMC78573.1 - 3.6e-29 98.5 20.7 6.8e-06 25.8 0.2 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EMC78573.1 - 9.1e-28 96.0 15.5 7.1e-09 35.4 0.4 5.1 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMC78573.1 - 1.4e-25 89.2 8.8 7e-08 32.9 0.2 4.9 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMC78573.1 - 2.5e-22 76.8 12.7 5.1e-05 22.7 0.3 7.5 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78573.1 - 1.5e-19 68.7 11.7 0.00099 19.5 0.1 8.6 2 1 7 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMC78573.1 - 3.5e-14 52.9 9.7 1.3e-05 25.4 0.8 5.2 2 1 3 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMC78573.1 - 1.4e-10 40.7 23.2 0.00096 19.0 0.3 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC78573.1 - 3.4e-10 38.9 6.1 1.4 8.9 0.1 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC78573.1 - 3.2e-05 24.0 5.0 1.9 9.1 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMC78573.1 - 6.8e-05 22.9 0.3 3.4 8.3 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC78573.1 - 0.0021 18.1 8.1 0.13 12.3 0.4 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMC78573.1 - 0.0059 16.4 1.5 0.24 11.2 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EMC78573.1 - 0.0067 15.2 2.4 0.38 9.4 0.1 2.6 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 EMC78573.1 - 0.029 14.4 3.8 0.73 9.9 0.1 3.8 3 1 2 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.12 EMC78573.1 - 0.24 11.7 1.9 6.6 7.0 0.0 2.7 3 0 0 3 3 2 0 Bacterial transcriptional activator domain EGF_2 PF07974.8 EMC78575.1 - 5.8e-41 138.3 208.7 5.4e-07 29.6 11.3 10.5 8 4 1 10 10 10 9 EGF-like domain hEGF PF12661.2 EMC78575.1 - 0.012 15.6 2.4 0.012 15.6 1.6 14.6 20 0 0 20 20 20 0 Human growth factor-like EGF EGF PF00008.22 EMC78575.1 - 0.022 14.6 9.6 0.022 14.6 6.7 11.9 9 2 1 11 11 11 0 EGF-like domain G8 PF10162.4 EMC78575.1 - 0.13 12.0 0.0 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 G8 domain FGF PF00167.13 EMC78576.1 - 4.2e-16 58.8 0.1 5.6e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Ion_trans PF00520.26 EMC78577.1 - 2e-23 82.7 4.0 2e-23 82.7 2.8 1.7 2 0 0 2 2 2 1 Ion transport protein PAS_9 PF13426.1 EMC78577.1 - 3.8e-17 62.5 0.0 7.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.24 EMC78577.1 - 3.1e-14 52.5 0.0 5.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 EMC78577.1 - 3.4e-12 45.9 3.7 3.4e-12 45.9 2.5 2.2 2 0 0 2 2 2 1 Ion channel PAS PF00989.19 EMC78577.1 - 9.4e-07 28.6 0.0 2.8e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EMC78577.1 - 0.00028 20.8 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold Ion_trans_N PF08412.5 EMC78577.1 - 0.0052 16.0 0.1 0.014 14.6 0.1 1.7 1 0 0 1 1 1 1 Ion transport protein N-terminal Cupin_3 PF05899.7 EMC78577.1 - 0.0068 15.7 0.4 0.046 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) PAS_4 PF08448.5 EMC78577.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold Cupin_2 PF07883.6 EMC78577.1 - 0.017 14.6 0.1 0.046 13.2 0.1 1.7 1 0 0 1 1 1 0 Cupin domain PAS_10 PF13596.1 EMC78577.1 - 0.098 12.9 0.1 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain NST1 PF13945.1 EMC78578.1 - 3.3 7.7 10.9 3.3 7.7 7.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator BRF1 PF07741.8 EMC78578.1 - 3.7 7.8 6.0 4 7.7 4.2 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Sporozoite_P67 PF05642.6 EMC78578.1 - 9.8 3.9 12.6 9.4 3.9 8.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RD3 PF14473.1 EMC78579.1 - 1.2e-50 170.4 3.2 1.6e-50 170.0 2.2 1.2 1 0 0 1 1 1 1 RD3 protein DUF2309 PF10070.4 EMC78579.1 - 0.02 12.9 0.6 0.026 12.6 0.4 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Utp12 PF04003.7 EMC78579.1 - 0.06 13.2 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Dip2/Utp12 Family RB_B PF01857.15 EMC78579.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Acyltransferase PF01553.16 EMC78581.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase DUF4517 PF15006.1 EMC78582.1 - 2e-51 174.0 0.0 2.4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) MlrC_C PF07171.7 EMC78582.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 MlrC C-terminus Ig_2 PF13895.1 EMC78583.1 - 1.2e-47 159.8 1.9 3.3e-13 49.5 0.0 5.3 4 1 1 5 5 5 5 Immunoglobulin domain I-set PF07679.11 EMC78583.1 - 6.8e-40 134.8 0.4 1.4e-08 34.4 0.0 7.3 5 3 1 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC78583.1 - 4.7e-30 103.8 4.2 2.8e-05 24.5 0.0 6.0 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 EMC78583.1 - 1.6e-26 92.2 4.5 0.00022 21.2 0.0 6.8 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 EMC78583.1 - 2.4e-24 85.4 0.1 0.022 14.6 0.1 8.1 3 2 1 5 5 5 5 Immunoglobulin V-set domain C1-set PF07654.10 EMC78583.1 - 9.8e-07 28.6 0.0 0.47 10.4 0.0 4.7 4 1 0 4 4 4 2 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC78583.1 - 1.6e-05 24.6 4.4 1.5 8.8 0.0 5.3 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 EMC78583.1 - 0.00012 21.9 0.0 1.4 8.9 0.0 5.2 7 0 0 7 7 7 1 Immunoglobulin C2-set domain BiPBP_C PF06832.7 EMC78583.1 - 0.0007 19.4 0.0 0.38 10.6 0.0 3.3 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Herpes_gE PF02480.11 EMC78583.1 - 0.0021 16.3 0.0 0.071 11.3 0.0 3.4 2 1 2 4 4 4 1 Alphaherpesvirus glycoprotein E DUF11 PF01345.13 EMC78583.1 - 0.094 12.7 2.5 23 5.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF11 Ig_2 PF13895.1 EMC78584.1 - 1e-13 51.1 0.1 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC78584.1 - 2.2e-10 40.8 0.2 4.6e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 EMC78584.1 - 8.7e-08 31.9 0.0 5.7e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 EMC78584.1 - 2.9e-06 27.1 0.0 0.00027 20.8 0.0 2.0 1 1 1 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 EMC78584.1 - 0.00055 19.9 0.1 0.0011 19.0 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Homeobox PF00046.24 EMC78585.1 - 2.5e-13 49.4 2.2 3e-13 49.1 1.5 1.1 1 0 0 1 1 1 1 Homeobox domain HTH_AsnC-type PF13404.1 EMC78585.1 - 0.034 13.6 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain CENP-B_N PF04218.8 EMC78585.1 - 0.13 11.7 0.4 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain ATP-synt_ab PF00006.20 EMC78587.1 - 9.9e-57 191.8 0.0 1.3e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC78587.1 - 9.2e-17 61.5 0.0 1.8e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC78587.1 - 7.1e-08 32.5 0.2 1.3e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RNA_capsid PF03035.9 EMC78588.1 - 0.046 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein IncA PF04156.9 EMC78588.1 - 0.77 9.3 19.5 0.63 9.6 2.5 2.3 2 0 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 EMC78588.1 - 0.94 9.3 16.7 1.1 9.1 3.7 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cut12 PF11500.3 EMC78588.1 - 2.4 7.8 5.4 2.4 7.8 0.3 2.4 2 0 0 2 2 2 0 Spindle pole body formation-associated protein TPR_MLP1_2 PF07926.7 EMC78588.1 - 3.5 7.3 10.8 0.4 10.4 2.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PAM2 PF07145.10 EMC78589.1 - 8.5e-07 28.0 0.1 8.5e-07 28.0 0.1 1.9 2 0 0 2 2 2 1 Ataxin-2 C-terminal region HAD_2 PF13419.1 EMC78589.1 - 0.087 13.0 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PT PF04886.7 EMC78590.1 - 2.7e-16 58.5 105.6 1.5e+04 -50.0 73.2 4.1 1 1 0 1 1 1 0 PT repeat C2 PF00168.25 EMC78591.1 - 7.2e-71 234.0 0.4 7.2e-18 64.2 0.0 7.3 8 0 0 8 8 8 6 C2 domain FerB PF08150.7 EMC78591.1 - 7.5e-38 128.4 0.0 1.7e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.7 EMC78591.1 - 3.6e-30 103.7 0.0 9.8e-30 102.3 0.0 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain FerA PF08165.6 EMC78591.1 - 4e-15 55.2 0.3 1e-14 53.9 0.2 1.7 1 0 0 1 1 1 1 FerA (NUC095) domain Pex24p PF06398.6 EMC78591.1 - 7.7e-06 24.9 5.5 7.7e-06 24.9 3.8 3.8 3 1 1 4 4 4 2 Integral peroxisomal membrane peroxin PTEN_C2 PF10409.4 EMC78591.1 - 0.00092 18.9 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Synaptobrevin PF00957.16 EMC78591.1 - 2.2 7.9 3.5 4.9 6.8 2.4 1.5 1 0 0 1 1 1 0 Synaptobrevin Ycf1 PF05758.7 EMC78593.1 - 0.00019 19.3 27.7 0.00026 18.8 19.2 1.3 1 0 0 1 1 1 1 Ycf1 MIP-T3 PF10243.4 EMC78593.1 - 0.00027 19.5 71.6 0.00034 19.2 49.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SAPS PF04499.10 EMC78593.1 - 0.017 13.7 22.7 0.02 13.5 15.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.4 EMC78593.1 - 0.018 13.7 32.3 0.02 13.5 22.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIF_alpha PF05793.7 EMC78593.1 - 0.27 9.5 61.1 0.36 9.1 42.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pilt PF15453.1 EMC78593.1 - 0.56 9.8 23.7 0.66 9.6 16.4 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions CDC45 PF02724.9 EMC78593.1 - 0.85 7.5 40.7 1.1 7.2 28.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF262 PF03235.9 EMC78593.1 - 1.3 8.9 19.5 1.7 8.5 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Parvo_coat PF00740.13 EMC78593.1 - 2.4 7.0 13.0 2.9 6.7 9.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PLRV_ORF5 PF01690.12 EMC78593.1 - 2.4 7.2 26.8 2.8 6.9 18.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SID-1_RNA_chan PF13965.1 EMC78593.1 - 3.7 5.6 11.0 4.6 5.3 7.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4551 PF15087.1 EMC78593.1 - 3.9 5.7 19.4 4.5 5.5 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nop14 PF04147.7 EMC78593.1 - 4.1 5.1 48.3 5.4 4.8 33.5 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 EMC78593.1 - 5.2 4.6 26.2 6.1 4.3 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2151 PF10221.4 EMC78593.1 - 8.8 4.3 27.0 9.9 4.1 18.7 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator BTB PF00651.26 EMC78594.1 - 5.5e-27 93.9 2.3 8.2e-13 48.3 0.0 3.6 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.17 EMC78594.1 - 6.1e-23 80.9 0.0 1.2e-22 79.9 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC78594.1 - 4e-12 46.6 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein zf-RING_4 PF14570.1 EMC78594.1 - 0.25 10.9 3.5 0.71 9.4 2.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SR-25 PF10500.4 EMC78594.1 - 6.4 6.1 12.0 13 5.1 8.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EMC78594.1 - 7 6.7 13.2 17 5.5 9.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Death PF00531.17 EMC78595.1 - 1e-17 63.6 0.1 1.5e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.13 EMC78595.1 - 9.2e-05 22.4 20.2 0.00015 21.7 10.4 3.9 4 0 0 4 4 4 2 TNFR/NGFR cysteine-rich region Tweety PF04906.8 EMC78595.1 - 0.39 9.0 4.1 0.21 9.9 1.4 1.5 2 0 0 2 2 2 0 Tweety Snf7 PF03357.16 EMC78596.1 - 2.3e-24 85.6 4.7 2.3e-24 85.6 3.3 2.0 2 0 0 2 2 2 1 Snf7 PspA_IM30 PF04012.7 EMC78596.1 - 9.2e-06 25.1 0.5 9.2e-06 25.1 0.3 2.0 2 0 0 2 2 2 1 PspA/IM30 family Snapin_Pallidin PF14712.1 EMC78596.1 - 0.0078 16.5 7.5 0.12 12.6 1.6 3.4 3 1 0 3 3 3 1 Snapin/Pallidin DUF342 PF03961.8 EMC78596.1 - 0.12 10.7 3.6 0.17 10.3 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF2951 PF11166.3 EMC78596.1 - 4.6 7.1 7.0 8.7 6.2 0.1 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF2951) 7tm_1 PF00001.16 EMC78597.1 - 1.8e-80 269.7 11.2 2.1e-80 269.5 7.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78597.1 - 7.6e-10 38.3 11.5 2.5e-09 36.6 8.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC78597.1 - 1.5e-08 34.1 4.6 2.3e-08 33.5 3.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC78597.1 - 1.3e-07 30.9 7.1 1.3e-07 30.9 4.9 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx DUF3390 PF11870.3 EMC78597.1 - 0.0056 16.5 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3390) CAAD PF14159.1 EMC78597.1 - 0.049 13.2 0.2 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2721 PF11026.3 EMC78597.1 - 0.14 11.8 4.6 3.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) R3H PF01424.17 EMC78598.1 - 7.9e-13 47.9 0.2 1.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 R3H domain DUF2414 PF10309.4 EMC78598.1 - 0.0067 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EMC78598.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain SRCR PF00530.13 EMC78599.1 - 7.5e-86 282.8 32.0 9.7e-30 102.8 3.3 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC78599.1 - 4.1e-23 81.4 13.6 1.1e-05 25.5 0.2 4.5 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 EMC78599.1 - 1.7e-06 28.2 5.0 0.14 12.3 0.2 4.2 4 0 0 4 4 4 2 Hepsin, SRCR GDA1_CD39 PF01150.12 EMC78601.1 - 4.9e-09 35.1 0.0 5.9e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Mito_carr PF00153.22 EMC78602.1 - 1.5e-13 50.2 0.0 2e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein Homeobox PF00046.24 EMC78603.1 - 2.5e-21 75.0 6.7 3.7e-21 74.4 4.6 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC78603.1 - 0.072 12.8 0.4 0.15 11.7 0.2 1.6 1 1 1 2 2 2 0 Homeobox KN domain Homeobox PF00046.24 EMC78604.1 - 2.9e-22 78.0 5.6 4e-22 77.5 3.9 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC78604.1 - 0.0096 14.9 0.3 0.013 14.5 0.2 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC78604.1 - 0.022 14.4 0.1 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Stanniocalcin PF03298.8 EMC78605.1 - 1.8e-102 340.7 5.4 2e-102 340.5 3.8 1.0 1 0 0 1 1 1 1 Stanniocalcin family CD45 PF12567.3 EMC78605.1 - 0.15 11.9 4.4 9.2 6.2 0.0 3.4 3 1 0 3 3 3 0 Leukocyte receptor CD45 Reprolysin PF01421.14 EMC78606.1 - 2.2e-32 112.2 3.0 2.2e-32 112.2 2.1 2.0 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC78606.1 - 8.3e-26 90.3 9.8 8.3e-26 90.3 6.8 4.0 4 1 0 4 4 3 1 ADAM cysteine-rich Disintegrin PF00200.18 EMC78606.1 - 1.4e-23 82.8 32.5 1.4e-23 82.8 22.5 4.5 4 2 0 4 4 2 1 Disintegrin Reprolysin_2 PF13574.1 EMC78606.1 - 7.6e-11 42.3 0.7 7.6e-11 42.3 0.5 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC78606.1 - 3.6e-09 36.4 0.4 3.6e-09 36.4 0.3 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMC78606.1 - 4e-09 37.0 0.2 8.9e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC78606.1 - 8.5e-08 32.3 0.8 8.5e-08 32.3 0.5 2.8 3 0 0 3 3 2 1 Metallo-peptidase family M12 Astacin PF01400.19 EMC78606.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 EMC78606.1 - 0.0031 17.2 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 EMC78606.1 - 0.022 14.3 0.1 0.052 13.1 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF3810 PF12725.2 EMC78606.1 - 0.054 12.3 0.1 0.074 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_M54 PF07998.6 EMC78606.1 - 0.066 12.9 0.3 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M54 DUF1025 PF06262.6 EMC78606.1 - 0.07 12.9 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M66 PF10462.4 EMC78606.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Collagen PF01391.13 EMC78608.1 - 4.5e-09 35.7 1.5 3.7e-07 29.5 1.0 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Filament PF00038.16 EMC78609.1 - 3.1e-83 279.8 37.3 1.1e-63 215.6 14.8 3.2 2 2 1 3 3 3 2 Intermediate filament protein Filament_head PF04732.9 EMC78609.1 - 4.9e-06 27.1 7.2 0.00049 20.7 0.2 2.6 2 0 0 2 2 2 2 Intermediate filament head (DNA binding) region Bacillus_HBL PF05791.6 EMC78609.1 - 0.00037 19.9 4.6 0.00037 19.9 3.2 2.4 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 EMC78609.1 - 0.0044 16.8 1.7 0.0044 16.8 1.2 3.7 2 1 3 5 5 5 1 Protein of unknown function (DUF1664) Rab5-bind PF09311.6 EMC78609.1 - 0.0064 16.4 19.8 0.0064 16.4 13.7 3.4 2 1 1 3 3 3 1 Rabaptin-like protein Vps23_core PF09454.5 EMC78609.1 - 0.031 13.8 2.2 0.042 13.4 0.3 2.2 2 0 0 2 2 2 0 Vps23 core domain Ly49 PF08391.5 EMC78609.1 - 6.8 6.8 7.5 2.4 8.3 1.1 2.7 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Baculo_PEP_C PF04513.7 EMC78609.1 - 7.1 6.4 13.9 8.3 6.2 2.9 3.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACCA PF03255.9 EMC78609.1 - 8.2 5.9 13.5 2.5 7.6 1.3 3.3 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DOCK-C2 PF14429.1 EMC78610.1 - 1.3e-57 194.4 0.4 3.5e-57 193.0 0.1 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EMC78610.1 - 1.6e-28 99.2 0.8 3.9e-28 97.9 0.2 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis SH3_9 PF14604.1 EMC78610.1 - 2.1e-09 36.8 0.0 4.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC78610.1 - 6.3e-09 35.0 0.0 1.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC78610.1 - 2.4e-06 26.9 0.0 5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GnRH PF00446.12 EMC78611.1 - 0.0022 17.9 5.3 0.0022 17.9 3.7 1.6 2 0 0 2 2 2 1 Gonadotropin-releasing hormone Gastrin PF00918.12 EMC78611.1 - 0.12 13.1 0.0 0.14 13.0 0.0 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Pentapeptide PF00805.17 EMC78612.1 - 4.8e-39 131.0 33.7 4.1e-13 48.2 1.0 4.8 2 2 3 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EMC78612.1 - 7.7e-22 76.8 1.8 1.7e-11 43.7 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 EMC78612.1 - 3.1e-20 72.1 0.0 5.2e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.1 EMC78612.1 - 6.6e-15 54.7 0.0 1.4e-05 24.8 0.0 4.6 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) DUF3354 PF11834.3 EMC78612.1 - 2.1e-10 40.0 0.0 3.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3354) BTB PF00651.26 EMC78612.1 - 1.4e-05 24.9 0.0 4.3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain PP1_bind PF15276.1 EMC78613.1 - 9.4e-20 70.4 0.3 1.2e-19 70.0 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 binding TIG PF01833.19 EMC78614.1 - 5.7e-13 48.6 0.1 1.8e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain WD40 PF00400.27 EMC78615.1 - 8.2e-15 54.0 1.8 0.83 9.6 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 EMC78615.1 - 0.04 13.2 0.5 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Tyrosine phosphatase family BNIP3 PF06553.7 EMC78616.1 - 4.2e-79 264.5 2.3 4.7e-79 264.3 1.6 1.0 1 0 0 1 1 1 1 BNIP3 Amidohydro_1 PF01979.15 EMC78617.1 - 5.6e-45 154.4 0.0 6.9e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC78617.1 - 2.5e-12 47.4 0.0 3.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMC78617.1 - 1.9e-09 37.2 2.7 2.4e-09 36.9 0.4 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC78617.1 - 1e-05 24.9 0.8 0.00018 20.8 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family 7tm_1 PF00001.16 EMC78618.1 - 9.1e-84 280.6 5.9 1.2e-83 280.1 4.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78618.1 - 2.1e-18 66.4 3.9 2.9e-18 65.9 2.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC78618.1 - 4.3e-07 29.3 0.2 7.1e-07 28.6 0.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC78618.1 - 3.3e-06 26.4 7.9 6.2e-06 25.5 5.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx RVT_1 PF00078.22 EMC78619.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.1 EMC78620.1 - 1.1e-54 181.9 43.6 5.7e-14 51.6 1.4 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EMC78620.1 - 2.1e-29 100.6 36.4 6.2e-07 28.8 3.3 6.4 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC78620.1 - 3.3e-21 72.0 34.9 0.01 15.7 0.3 11.2 11 0 0 11 11 11 9 Leucine Rich Repeat LRR_5 PF13306.1 EMC78620.1 - 6.1e-20 71.2 0.6 2e-09 37.2 0.0 2.5 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC78620.1 - 3.1e-10 38.5 34.7 0.37 11.1 0.2 9.9 10 0 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 EMC78620.1 - 3.4e-08 32.7 32.3 0.47 10.6 0.4 9.2 9 1 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 EMC78620.1 - 1.4e-07 31.2 0.8 0.0043 16.6 0.2 2.8 1 1 1 2 2 2 2 Leucine-rich repeat DUF3481 PF11980.3 EMC78620.1 - 0.0051 16.6 0.6 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3481) LRRNT PF01462.13 EMC78620.1 - 0.024 14.0 3.4 0.051 13.0 1.3 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Viral_env_E26 PF11050.3 EMC78620.1 - 0.095 11.8 1.2 0.46 9.6 0.6 2.2 2 0 0 2 2 2 0 Virus envelope protein E26 EGF PF00008.22 EMC78621.1 - 0.00067 19.5 4.4 0.0012 18.7 3.1 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.8 EMC78621.1 - 0.0012 18.9 7.6 0.0023 18.0 5.2 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 EMC78621.1 - 0.028 14.4 1.7 0.028 14.4 1.2 2.0 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.19 EMC78621.1 - 0.058 13.3 4.2 0.08 12.8 2.9 1.3 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) DUF3844 PF12955.2 EMC78621.1 - 0.092 12.8 1.0 0.12 12.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) DUF1180 PF06679.7 EMC78621.1 - 1.1 9.1 3.8 1.7 8.5 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF842 PF05811.8 EMC78622.1 - 4.1e-36 123.3 8.0 4.5e-36 123.1 5.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Vicilin_N PF04702.7 EMC78622.1 - 0.099 12.2 7.8 0.12 11.9 5.4 1.2 1 1 0 1 1 1 0 Vicilin N terminal region zf-Tim10_DDP PF02953.10 EMC78622.1 - 0.74 9.1 10.2 0.82 8.9 0.1 2.4 1 1 1 2 2 2 0 Tim10/DDP family zinc finger LSM PF01423.17 EMC78623.1 - 2.8e-18 65.2 0.2 3.1e-18 65.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain Prenylcys_lyase PF07156.9 EMC78624.1 - 3.6e-121 404.5 0.0 4.1e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase RRM_1 PF00076.17 EMC78625.1 - 1.2e-65 217.0 0.0 3.1e-23 81.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78625.1 - 5.3e-35 119.2 0.0 1.2e-14 54.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78625.1 - 5e-31 106.3 0.3 8.6e-10 38.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EMC78625.1 - 8.9e-07 28.6 0.0 0.0015 18.1 0.0 3.0 3 0 0 3 3 3 2 Calcipressin Nup35_RRM_2 PF14605.1 EMC78625.1 - 7.1e-06 25.6 0.9 0.0088 15.7 0.0 3.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMC78625.1 - 8.2e-05 22.4 0.0 0.33 10.8 0.0 3.1 2 1 1 3 3 3 2 RNA binding motif Nup35_RRM PF05172.8 EMC78625.1 - 0.0026 17.4 0.3 0.15 11.8 0.1 3.1 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 EMC78625.1 - 0.047 13.6 0.1 6.5 6.8 0.0 2.8 2 0 0 2 2 2 0 RNA binding domain DbpA PF03880.10 EMC78625.1 - 0.085 12.5 0.0 7.6 6.2 0.0 3.0 3 0 0 3 3 3 0 DbpA RNA binding domain HATPase_c PF02518.21 EMC78625.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HCaRG PF07258.9 EMC78627.1 - 1.1e-16 60.9 0.0 1.3e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 HCaRG protein Arm PF00514.18 EMC78628.1 - 1.4e-36 123.0 20.1 2.3e-07 30.3 0.0 9.2 8 1 1 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EMC78628.1 - 3e-17 61.0 9.1 0.058 13.4 0.1 7.6 7 1 1 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 EMC78628.1 - 2.3e-16 59.8 9.7 4.4e-05 23.6 0.7 5.2 2 2 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 EMC78628.1 - 7e-14 51.8 10.2 0.00025 21.4 0.4 5.9 4 1 3 7 7 5 3 HEAT-like repeat Adaptin_N PF01602.15 EMC78628.1 - 1.4e-09 36.8 3.7 0.0077 14.6 0.3 3.7 2 1 0 3 3 3 3 Adaptin N terminal region Proteasom_PSMB PF10508.4 EMC78628.1 - 2.7e-07 29.2 0.9 0.00014 20.2 0.1 2.5 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EMC78628.1 - 1.5e-05 24.9 0.5 1 9.1 0.1 4.6 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.6 EMC78628.1 - 8.7e-05 22.1 0.0 1.2 8.5 0.0 3.4 2 1 0 3 3 3 2 DNA alkylation repair enzyme RICTOR_V PF14668.1 EMC78628.1 - 0.00049 19.9 2.7 0.36 10.8 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EMC78628.1 - 0.0028 17.9 6.0 0.21 12.1 0.2 4.6 5 0 0 5 5 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EMC78628.1 - 0.0049 16.2 0.1 26 4.0 0.0 3.6 1 1 0 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.4 EMC78628.1 - 0.018 14.7 0.2 4 7.2 0.0 3.2 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF3731 PF12531.3 EMC78628.1 - 0.029 13.9 1.0 6.6 6.1 0.1 2.5 2 1 0 2 2 2 0 DNA-K related protein V-ATPase_H_C PF11698.3 EMC78628.1 - 0.06 13.2 0.4 4.6 7.1 0.1 3.3 4 0 0 4 4 4 0 V-ATPase subunit H MMS19_C PF12460.3 EMC78628.1 - 0.083 11.5 2.6 9.2 4.8 0.0 3.6 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal DUF2336 PF10098.4 EMC78628.1 - 0.11 11.6 2.9 0.1 11.8 0.3 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2336) PIP5K PF01504.13 EMC78629.1 - 5.8e-73 245.0 0.1 7.2e-73 244.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Arm PF00514.18 EMC78630.1 - 6.9e-49 162.0 25.1 7.7e-08 31.8 0.0 11.8 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC78630.1 - 8.4e-33 112.5 16.6 7.8e-07 29.2 2.7 6.4 1 1 4 6 6 6 6 HEAT repeats EDR1 PF14381.1 EMC78630.1 - 6e-28 97.8 0.2 1.6e-22 80.1 0.0 3.3 4 0 0 4 4 4 2 Ethylene-responsive protein kinase Le-CTR1 HEAT PF02985.17 EMC78630.1 - 5.2e-24 82.1 18.9 0.00026 20.7 0.0 10.0 11 0 0 11 11 10 5 HEAT repeat Adaptin_N PF01602.15 EMC78630.1 - 6e-13 47.9 8.3 1.7e-08 33.3 3.3 3.3 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EMC78630.1 - 1e-11 44.9 17.0 0.0059 17.0 0.0 8.9 9 0 0 9 9 9 2 HEAT-like repeat V-ATPase_H_C PF11698.3 EMC78630.1 - 6.8e-09 35.6 4.8 0.083 12.8 0.0 5.8 2 2 6 8 8 8 2 V-ATPase subunit H V-ATPase_H_N PF03224.9 EMC78630.1 - 2.7e-06 26.7 1.1 0.019 14.0 0.0 3.5 1 1 1 2 2 2 2 V-ATPase subunit H Cnd1 PF12717.2 EMC78630.1 - 4.2e-06 26.7 1.4 0.85 9.4 0.1 5.6 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 EMC78630.1 - 1.5e-05 24.2 12.4 1 8.4 1.1 5.8 1 1 3 4 4 4 4 Armadillo-like Proteasom_PSMB PF10508.4 EMC78630.1 - 0.0084 14.4 14.3 0.81 7.8 5.2 4.2 2 1 2 4 4 4 1 Proteasome non-ATPase 26S subunit PDCD2_C PF04194.8 EMC78630.1 - 0.032 13.8 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain DRIM PF07539.7 EMC78630.1 - 0.078 12.3 2.2 32 3.9 0.0 4.4 4 0 0 4 4 4 0 Down-regulated in metastasis ALF PF03752.8 EMC78630.1 - 6.8 6.6 8.8 0.19 11.6 0.3 2.7 3 0 0 3 3 3 0 Short repeats of unknown function OTU PF02338.14 EMC78631.1 - 2.7e-21 76.3 0.0 4.1e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EMC78631.1 - 0.0039 16.5 0.1 0.1 11.9 0.1 2.3 1 1 0 2 2 2 1 Peptidase C65 Otubain RhoGAP PF00620.22 EMC78633.1 - 2.3e-50 170.1 0.0 4.4e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.1 EMC78633.1 - 2.3e-14 53.5 0.0 7.4e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMC78633.1 - 5.6e-14 52.1 1.3 2e-13 50.4 0.1 2.7 2 0 0 2 2 2 1 PH domain PDZ PF00595.19 EMC78633.1 - 1.4e-10 41.1 0.1 4.7e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC78633.1 - 5.9e-07 29.2 0.1 2.7e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PH_11 PF15413.1 EMC78633.1 - 0.011 16.0 0.1 0.053 13.7 0.1 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain Pribosyltran PF00156.22 EMC78634.1 - 8e-07 28.8 0.0 0.023 14.3 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Enkurin PF13864.1 EMC78635.1 - 5.3e-25 87.4 8.6 5.3e-25 87.4 6.0 2.5 3 1 0 3 3 3 1 Calmodulin-binding XkdW PF09636.5 EMC78635.1 - 0.18 11.6 4.2 0.084 12.7 0.6 2.1 2 1 0 2 2 2 0 XkdW protein MOSC_N PF03476.11 EMC78636.1 - 9e-30 102.8 0.0 1.6e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EMC78636.1 - 7.9e-25 86.8 0.0 1.9e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 EMC78636.1 - 2.3e-21 75.9 0.0 6.1e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V FERM_N PF09379.5 EMC78637.1 - 1.2e-19 70.1 0.0 2.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 EMC78637.1 - 2.5e-12 47.0 0.0 3.7e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 FERM central domain Trm112p PF03966.11 EMC78637.1 - 0.0062 16.8 0.0 4 7.8 0.0 2.8 2 1 1 3 3 3 2 Trm112p-like protein Y_phosphatase PF00102.22 EMC78638.1 - 2.2e-80 269.3 1.6 2.6e-80 269.1 1.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC78638.1 - 2.3e-06 27.2 0.1 3.8e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC78638.1 - 2.3e-05 24.4 0.3 3.9e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC78638.1 - 0.00031 21.0 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.9 EMC78638.1 - 0.069 11.9 0.1 0.13 11.0 0.0 1.4 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.8 EMC78638.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family FERM_C PF09380.5 EMC78640.1 - 6.6e-21 74.3 0.0 1.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 EMC78640.1 - 7.8e-18 64.3 0.3 2.8e-17 62.5 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 EMC78640.1 - 1.1e-16 61.1 0.2 2.4e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 FERM central domain FA PF08736.6 EMC78640.1 - 1.9e-12 46.7 10.9 1.9e-12 46.7 7.6 1.8 2 0 0 2 2 2 1 FERM adjacent (FA) DOMON PF03351.12 EMC78641.1 - 2.3e-23 82.4 0.0 2.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 DOMON domain Ribosomal_S19e PF01090.14 EMC78643.1 - 0.0041 16.5 0.2 0.47 9.8 0.0 3.1 3 0 0 3 3 3 1 Ribosomal protein S19e zf-C4H2 PF10146.4 EMC78643.1 - 0.042 13.8 4.1 0.021 14.8 1.1 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein AMPKBI PF04739.10 EMC78644.1 - 1.1e-29 102.2 0.4 1.7e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain CBM_48 PF02922.13 EMC78644.1 - 0.056 13.4 0.1 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CNH PF00780.17 EMC78645.1 - 9.3e-60 202.3 0.0 2e-59 201.2 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 EMC78645.1 - 9.6e-55 185.5 0.0 9.6e-55 185.5 0.0 3.0 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78645.1 - 6.9e-28 97.4 0.0 2e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EMC78645.1 - 8.9e-06 25.3 9.3 2.1e-05 24.1 6.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 EMC78645.1 - 0.00018 21.6 0.0 0.00073 19.7 0.0 2.2 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.6 EMC78645.1 - 0.00044 19.1 0.0 0.0015 17.4 0.0 1.9 1 0 0 1 1 1 1 Seadornavirus VP7 V_ATPase_I PF01496.14 EMC78645.1 - 0.0012 16.7 15.1 0.0012 16.7 10.4 6.1 1 1 4 5 5 5 1 V-type ATPase 116kDa subunit family Pkinase_C PF00433.19 EMC78645.1 - 0.0015 19.0 1.0 0.0043 17.5 0.7 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EMC78645.1 - 0.0044 16.7 0.0 0.0044 16.7 0.0 4.4 5 2 0 5 5 5 1 Phosphotransferase enzyme family DUF1601 PF07671.6 EMC78646.1 - 0.023 14.3 4.5 2.9 7.6 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) bZIP_2 PF07716.10 EMC78646.1 - 0.04 13.7 1.5 0.04 13.7 1.0 8.3 5 3 3 8 8 8 0 Basic region leucine zipper bZIP_1 PF00170.16 EMC78646.1 - 1.8 8.6 41.5 0.45 10.5 1.0 6.6 5 2 2 7 7 7 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 EMC78646.1 - 5.1 6.9 74.8 3 7.6 13.0 5.3 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ras PF00071.17 EMC78647.1 - 2.6e-55 186.2 0.5 3.4e-55 185.8 0.4 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC78647.1 - 2.1e-16 60.5 0.2 4.8e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC78647.1 - 7.4e-16 57.8 0.2 1e-15 57.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC78647.1 - 1.4e-07 31.1 0.1 2.4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC78647.1 - 0.0037 16.4 0.8 0.0087 15.2 0.6 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC78647.1 - 0.0061 16.5 0.3 0.0094 15.8 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase HTH_3 PF01381.17 EMC78651.1 - 7.4e-13 48.1 0.2 1e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 EMC78651.1 - 4.4e-08 33.0 0.9 8.5e-08 32.1 0.1 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_19 PF12844.2 EMC78651.1 - 1.1e-05 25.3 0.1 1.5e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EMC78651.1 - 0.00023 21.2 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 EMC78651.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ocnus PF05005.10 EMC78652.1 - 6.7e-21 74.1 0.1 7.3e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) PPO1_DWL PF12142.3 EMC78652.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Ras PF00071.17 EMC78653.1 - 7.9e-12 44.8 0.1 1e-05 24.9 0.2 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EMC78653.1 - 3.6e-08 33.9 0.0 3.6e-08 33.9 0.0 3.3 3 1 0 3 3 3 1 Miro-like protein Arf PF00025.16 EMC78653.1 - 5.5e-06 25.7 0.1 1.8e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC78653.1 - 0.0019 18.1 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EMC78653.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Kunitz_BPTI PF00014.18 EMC78654.1 - 3.7e-36 123.0 19.4 2.5e-18 66.0 4.5 2.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lipocalin PF00061.18 EMC78654.1 - 2e-26 92.7 0.0 2.7e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SPRR2 PF14820.1 EMC78654.1 - 1 9.2 6.5 0.3 10.9 1.6 2.2 2 0 0 2 2 2 0 Small proline-rich 2 Mut7-C PF01927.11 EMC78655.1 - 9.4e-07 28.9 0.0 1.1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain TFIIS_C PF01096.13 EMC78655.1 - 5.3 6.7 7.0 2.5 7.7 2.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF3613 PF12266.3 EMC78659.1 - 0.06 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Tropomodulin PF03250.9 EMC78660.1 - 3.3e-20 72.1 0.0 7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.1 EMC78660.1 - 0.0054 16.6 2.2 0.022 14.7 0.1 2.9 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.2 EMC78660.1 - 0.11 12.1 2.1 3.4 7.3 1.4 2.6 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Tropomodulin PF03250.9 EMC78661.1 - 2e-13 50.0 1.5 2.2e-13 49.9 1.0 1.0 1 0 0 1 1 1 1 Tropomodulin Cut8_M PF14483.1 EMC78661.1 - 0.041 13.6 0.9 0.058 13.1 0.6 1.2 1 0 0 1 1 1 0 Cut8 dimerisation domain L_biotic_typeA PF04604.8 EMC78661.1 - 0.63 9.7 2.4 0.8 9.3 0.3 2.0 2 0 0 2 2 2 0 Type-A lantibiotic DUF3007 PF11460.3 EMC78661.1 - 0.75 9.8 3.2 0.86 9.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) PIP5K PF01504.13 EMC78662.1 - 1.3e-78 263.6 0.1 1.8e-78 263.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase UIM PF02809.15 EMC78663.1 - 4.5e-11 41.3 6.7 1.6e-05 24.0 0.7 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif VWA_2 PF13519.1 EMC78663.1 - 0.00041 20.4 0.7 0.022 14.8 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain DAGK_cat PF00781.19 EMC78663.1 - 0.051 13.0 0.2 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain SGT1 PF07093.6 EMC78663.1 - 0.25 9.6 6.4 0.32 9.3 4.4 1.1 1 0 0 1 1 1 0 SGT1 protein K_channel_TID PF07941.6 EMC78663.1 - 2.4 8.4 9.1 0.37 11.0 3.1 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain RFX_DNA_binding PF02257.10 EMC78664.1 - 7.6e-24 83.6 1.1 3e-23 81.7 0.7 1.8 1 1 0 1 1 1 1 RFX DNA-binding domain SBP56 PF05694.6 EMC78666.1 - 1.4e-181 604.0 0.0 1.6e-181 603.8 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EMC78666.1 - 0.003 16.6 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.6 EMC78667.1 - 2.7e-143 477.8 0.0 3e-143 477.6 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EMC78667.1 - 0.00066 18.8 0.0 0.002 17.3 0.0 1.7 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SH3_6 PF12913.2 EMC78667.1 - 0.052 12.7 0.2 0.57 9.4 0.0 2.5 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type SGL PF08450.7 EMC78667.1 - 0.13 11.6 0.0 0.83 8.9 0.0 2.1 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region SBP56 PF05694.6 EMC78668.1 - 1.4e-219 729.2 0.0 1.7e-219 729.0 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EMC78668.1 - 0.00018 20.7 0.0 0.0017 17.5 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller zf-C2H2_4 PF13894.1 EMC78669.1 - 5.6e-05 23.1 53.2 0.0036 17.5 0.4 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC78669.1 - 9.6e-05 22.5 54.5 0.13 12.6 0.5 6.8 6 1 0 6 6 6 5 Zinc finger, C2H2 type zf-Di19 PF05605.7 EMC78669.1 - 0.00062 19.8 32.3 0.16 12.1 0.3 4.7 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EMC78669.1 - 0.0022 18.0 24.6 0.16 12.1 0.4 5.6 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Rubredoxin PF00301.15 EMC78669.1 - 0.41 10.5 12.9 1.1 9.1 0.0 5.6 7 0 0 7 7 7 0 Rubredoxin DUF2757 PF10955.3 EMC78669.1 - 0.54 10.4 6.9 0.42 10.8 2.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) zinc_ribbon_4 PF13717.1 EMC78669.1 - 0.68 9.6 0.1 0.68 9.6 0.0 5.4 6 0 0 6 6 6 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMC78669.1 - 3.1 7.4 20.1 0.75 9.4 0.0 5.4 6 0 0 6 6 6 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 EMC78669.1 - 4.2 7.5 34.1 3.7 7.7 0.9 5.4 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) PT PF04886.7 EMC78670.1 - 1.1e-07 30.9 178.9 0.57 9.5 6.5 11.0 1 1 8 9 9 9 7 PT repeat KCNQC3-Ank-G_bd PF11956.3 EMC78670.1 - 0.082 12.9 17.7 3.3 7.8 0.6 3.9 1 1 2 3 3 3 0 Ankyrin-G binding motif of KCNQ2-3 ERbeta_N PF12497.3 EMC78671.1 - 0.047 13.5 1.1 0.059 13.2 0.7 1.2 1 0 0 1 1 1 0 Estrogen receptor beta Proteasome PF00227.21 EMC78672.1 - 4.6e-21 74.9 0.0 5.1e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 EMC78672.1 - 0.09 12.3 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain PCP_red PF08369.5 EMC78672.1 - 0.16 11.8 0.3 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Retinal PF15449.1 EMC78673.1 - 0 1215.2 45.9 0 1215.0 31.8 1.0 1 0 0 1 1 1 1 Retinal protein CAP_GLY PF01302.20 EMC78674.1 - 3.7e-73 241.1 4.6 6.6e-25 86.5 0.3 3.3 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.2 EMC78674.1 - 2.3e-12 47.1 0.3 6.3e-09 36.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC78674.1 - 3.2e-12 45.6 2.2 3.8e-06 26.4 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EMC78674.1 - 1.6e-07 31.6 0.3 3.9e-05 24.0 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC78674.1 - 3.4e-07 29.8 2.1 0.015 15.5 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC78674.1 - 3.7e-06 26.9 1.5 0.45 10.8 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TrkA_C PF02080.16 EMC78674.1 - 0.13 11.8 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 TrkA-C domain RRM_1 PF00076.17 EMC78677.1 - 2.1e-44 148.9 0.7 3.8e-15 55.2 0.3 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78677.1 - 7e-35 118.8 0.0 2.8e-12 46.4 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78677.1 - 3.9e-18 65.0 0.4 1.7e-05 24.6 0.1 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC78677.1 - 0.00067 19.3 1.2 0.73 9.6 0.2 3.7 2 2 1 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 EMC78677.1 - 0.0062 16.2 0.1 2.8 7.7 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EMC78677.1 - 0.035 13.6 0.2 0.47 10.0 0.1 2.4 1 1 1 2 2 2 0 Calcipressin IATP PF04568.7 EMC78678.1 - 4.1e-11 42.7 10.8 4.1e-11 42.7 7.5 2.1 2 1 1 3 3 2 1 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.10 EMC78678.1 - 0.0061 16.0 4.1 0.0074 15.7 2.6 1.4 1 1 0 1 1 1 1 Septum formation initiator Prefoldin_2 PF01920.15 EMC78678.1 - 0.01 15.5 3.9 0.011 15.5 2.7 1.1 1 0 0 1 1 1 0 Prefoldin subunit THOC7 PF05615.8 EMC78678.1 - 0.013 15.8 5.6 0.015 15.5 3.9 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 Fib_alpha PF08702.5 EMC78678.1 - 0.015 15.4 2.5 0.016 15.3 1.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 EMC78678.1 - 0.021 14.8 3.5 0.023 14.7 2.4 1.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_lysis PF03245.8 EMC78678.1 - 0.021 14.8 2.2 0.025 14.5 1.5 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Bap31 PF05529.7 EMC78678.1 - 0.034 13.6 3.4 0.036 13.5 2.4 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 EMC78678.1 - 0.035 14.5 1.0 0.041 14.3 0.7 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 EMC78678.1 - 0.045 12.6 3.8 0.047 12.6 2.6 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EMC78678.1 - 0.053 12.1 4.2 0.055 12.1 2.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4078 PF13300.1 EMC78678.1 - 0.053 13.6 4.8 0.058 13.5 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) Sipho_Gp157 PF05565.6 EMC78678.1 - 0.059 12.9 4.4 0.066 12.7 3.1 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 DUF2968 PF11180.3 EMC78678.1 - 0.081 12.3 1.2 0.09 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spectrin PF00435.16 EMC78678.1 - 0.089 13.0 5.5 0.1 12.9 3.8 1.1 1 0 0 1 1 1 0 Spectrin repeat TMF_DNA_bd PF12329.3 EMC78678.1 - 0.1 12.4 9.2 0.13 12.1 6.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EMC78678.1 - 0.14 12.0 5.1 0.16 11.8 3.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 EMC78678.1 - 0.17 11.6 2.4 0.19 11.4 1.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.1 EMC78678.1 - 0.22 10.4 1.2 0.24 10.3 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1640 PF07798.6 EMC78678.1 - 0.24 11.4 4.1 0.26 11.3 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3450 PF11932.3 EMC78678.1 - 0.26 10.5 1.9 0.29 10.3 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4349 PF14257.1 EMC78678.1 - 0.29 10.3 1.3 0.31 10.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF812 PF05667.6 EMC78678.1 - 0.29 9.5 4.5 0.32 9.4 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1192 PF06698.6 EMC78678.1 - 0.31 10.8 3.0 0.5 10.2 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Pox_A_type_inc PF04508.7 EMC78678.1 - 0.4 10.5 7.8 1.8 8.5 0.6 3.1 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Dzip-like_N PF13815.1 EMC78678.1 - 0.45 10.3 4.8 0.52 10.1 3.4 1.1 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal bZIP_1 PF00170.16 EMC78678.1 - 0.49 10.3 6.0 0.78 9.7 4.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF4200 PF13863.1 EMC78678.1 - 0.53 10.2 11.9 0.62 10.0 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4446 PF14584.1 EMC78678.1 - 0.55 10.0 2.5 0.59 9.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ABC_tran_2 PF12848.2 EMC78678.1 - 0.66 9.8 9.3 0.84 9.5 6.4 1.1 1 0 0 1 1 1 0 ABC transporter Borrelia_P83 PF05262.6 EMC78678.1 - 0.72 8.0 5.6 0.75 8.0 3.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Val_tRNA-synt_C PF10458.4 EMC78678.1 - 0.84 9.7 7.8 0.18 11.8 2.3 1.9 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF342 PF03961.8 EMC78678.1 - 1.3 7.3 4.9 1.5 7.1 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Med28 PF11594.3 EMC78678.1 - 1.5 9.1 5.0 1.8 8.8 3.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 28 IncA PF04156.9 EMC78678.1 - 1.8 8.1 5.4 2.1 7.9 3.7 1.1 1 0 0 1 1 1 0 IncA protein DUF1049 PF06305.6 EMC78678.1 - 3.6 7.1 4.9 8 6.0 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) DnaJ PF00226.26 EMC78679.1 - 1.6e-19 69.3 1.6 5.3e-19 67.7 1.1 1.9 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EMC78679.1 - 0.014 14.7 0.1 0.042 13.2 0.1 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF4320 PF14208.1 EMC78679.1 - 0.024 14.5 1.6 0.041 13.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Cytochrom_C1 PF02167.10 EMC78679.1 - 1 8.9 6.7 2.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C1 family 7tm_1 PF00001.16 EMC78680.1 - 2e-48 164.7 21.2 2.9e-48 164.2 14.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 EMC78680.1 - 0.023 14.4 0.9 0.023 14.4 0.6 3.2 1 1 1 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa DUF912 PF06024.7 EMC78680.1 - 0.54 10.3 6.7 0.22 11.5 0.2 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7TM_GPCR_Str PF10326.4 EMC78680.1 - 3.9 6.5 28.2 1.3e+03 -1.9 19.5 3.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str YTH PF04146.10 EMC78681.1 - 1.3e-48 164.1 0.1 2e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain HLH PF00010.21 EMC78682.1 - 6.3e-12 45.0 0.0 9.2e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ArfGap PF01412.13 EMC78683.1 - 3.3e-35 120.3 0.6 2.8e-34 117.3 0.0 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EMC78683.1 - 2.9e-11 43.5 0.4 9.6e-11 41.8 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH PF00169.24 EMC78683.1 - 2.2e-10 40.6 1.0 5.2e-10 39.4 0.2 2.0 2 0 0 2 2 2 1 PH domain Ank_5 PF13857.1 EMC78683.1 - 7.9e-09 35.4 1.0 3.4e-08 33.4 0.2 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EMC78683.1 - 1.2e-08 34.3 2.4 3.5e-07 29.7 0.2 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EMC78683.1 - 8.4e-08 32.5 0.6 1.5e-06 28.5 0.2 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC78683.1 - 3.5e-06 26.7 1.2 0.0038 17.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat PH_3 PF14593.1 EMC78683.1 - 0.0087 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF3007 PF11460.3 EMC78683.1 - 0.048 13.7 0.4 2.4 8.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) RCC1 PF00415.13 EMC78684.1 - 2.4e-44 149.2 10.4 2.4e-10 40.4 0.1 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC78684.1 - 7.3e-14 50.9 23.0 0.0035 16.9 1.5 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1 PF00112.18 EMC78685.1 - 1.6e-66 224.3 3.5 2e-66 224.0 2.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EMC78685.1 - 6e-10 39.2 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EMC78685.1 - 0.0017 16.9 0.2 0.056 11.9 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase_Tyr PF07714.12 EMC78686.1 - 8.4e-95 316.7 0.0 1e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC78686.1 - 2.2e-51 174.4 0.0 3e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC78686.1 - 8.7e-25 86.3 0.0 2.3e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 EMC78686.1 - 6.2e-05 22.4 0.4 0.00018 21.0 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.18 EMC78686.1 - 0.00015 21.5 0.0 0.035 13.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family SH3_2 PF07653.12 EMC78686.1 - 0.00051 19.4 0.5 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC78686.1 - 0.00054 19.2 0.4 0.0026 17.1 0.1 2.2 2 0 0 2 2 2 1 SH3 domain 7tm_1 PF00001.16 EMC78690.1 - 1.9e-38 132.0 22.3 2.3e-38 131.8 15.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MGC-24 PF05283.6 EMC78691.1 - 3.1e-19 69.4 18.2 3.7e-17 62.7 12.6 2.0 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) DUF778 PF05608.7 EMC78692.1 - 4e-43 146.6 3.0 3.9e-42 143.4 2.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF778) CTX_RstB PF07459.6 EMC78692.1 - 0.0021 17.8 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 CTX phage RstB protein WD40 PF00400.27 EMC78694.1 - 2.3e-34 116.0 3.6 7.5e-08 31.9 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat TPR_11 PF13414.1 EMC78694.1 - 7.3e-17 60.7 11.2 5.9e-14 51.4 2.9 2.5 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 EMC78694.1 - 1.5e-07 31.0 1.4 0.0058 16.7 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC78694.1 - 5.9e-07 29.7 0.7 0.0058 16.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC78694.1 - 5.1e-06 26.0 8.9 0.043 13.7 0.3 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC78694.1 - 1.3e-05 24.5 10.4 0.11 12.0 0.6 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC78694.1 - 1.8e-05 25.2 2.4 0.02 15.5 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78694.1 - 3.4e-05 24.1 0.7 0.17 12.6 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC78694.1 - 6.5e-05 22.9 4.6 0.00012 22.0 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC78694.1 - 0.00018 21.7 0.2 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC78694.1 - 0.17 11.7 2.2 0.27 11.1 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1693 PF07984.7 EMC78695.1 - 4.6e-161 535.3 2.2 5.3e-161 535.1 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) CS PF04969.11 EMC78696.1 - 3.2e-18 66.0 0.3 1e-17 64.4 0.0 2.0 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.1 EMC78696.1 - 1.6e-15 56.7 1.0 4.2e-15 55.4 0.7 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. BSMAP PF12280.3 EMC78696.1 - 8.5 6.2 9.7 1.1 9.0 0.4 2.8 2 1 1 3 3 3 0 Brain specific membrane anchored protein G-patch PF01585.18 EMC78697.1 - 6.3e-09 35.4 1.2 6.3e-09 35.4 0.8 1.6 2 0 0 2 2 2 1 G-patch domain ATP_bind_1 PF03029.12 EMC78698.1 - 7e-85 284.3 0.0 8.3e-85 284.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EMC78698.1 - 0.00014 22.6 0.1 0.00055 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EMC78698.1 - 0.0027 16.5 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 EMC78698.1 - 0.0036 17.0 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EMC78698.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 EMC78698.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMC78698.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC78698.1 - 0.032 14.5 0.4 0.43 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMC78698.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMC78698.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EMC78698.1 - 0.058 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EMC78698.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC78698.1 - 0.068 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 EMC78698.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EMC78698.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMC78698.1 - 0.15 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EMC78698.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain 14-3-3 PF00244.15 EMC78699.1 - 1.2e-106 355.1 8.2 1.3e-106 354.9 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein His_Phos_2 PF00328.17 EMC78699.1 - 0.0044 16.3 0.6 0.0051 16.1 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PMEI PF04043.10 EMC78699.1 - 0.037 13.9 1.3 1 9.2 0.2 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor TPR_12 PF13424.1 EMC78699.1 - 0.041 13.8 0.2 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Anticodon_1 PF08264.8 EMC78699.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA WXG100 PF06013.7 EMC78699.1 - 0.081 12.9 1.5 6.1 6.9 0.0 3.2 4 0 0 4 4 4 0 Proteins of 100 residues with WXG DUF837 PF05769.6 EMC78699.1 - 0.084 12.3 4.8 0.11 11.9 0.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF837) CCDC-167 PF15188.1 EMC78699.1 - 0.1 12.5 0.9 0.8 9.6 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FliM PF02154.10 EMC78699.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Flagellar motor switch protein FliM DOG1 PF14144.1 EMC78699.1 - 0.18 11.8 1.9 0.68 10.0 0.1 2.4 2 1 0 2 2 2 0 Seed dormancy control zf-DHHC PF01529.15 EMC78700.1 - 1.3e-35 122.3 10.2 1.7e-35 122.0 7.1 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Tic20 PF09685.5 EMC78700.1 - 4.9e-05 23.2 1.2 6.7e-05 22.8 0.8 1.2 1 0 0 1 1 1 1 Tic20-like protein PGG PF13962.1 EMC78700.1 - 0.017 14.7 2.0 0.027 14.0 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF998 PF06197.8 EMC78700.1 - 1.8 7.8 10.4 2.5 7.3 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Pkinase PF00069.20 EMC78702.1 - 7.5e-148 490.6 0.0 4.5e-74 248.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78702.1 - 6.8e-78 261.3 0.0 3.3e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC78702.1 - 4.8e-16 58.5 0.0 9.4e-08 31.3 0.0 3.5 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EMC78702.1 - 1.8e-10 40.2 0.0 5.6e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC78702.1 - 1.1e-05 24.8 0.0 0.0078 15.5 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.18 EMC78702.1 - 3.1e-05 23.8 0.0 0.2 11.3 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family tRNA-synt_1f PF01921.13 EMC78702.1 - 0.00057 18.6 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) RIO1 PF01163.17 EMC78702.1 - 0.01 15.1 0.0 0.4 9.9 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Pkinase_C PF00433.19 EMC78702.1 - 0.017 15.6 0.0 0.043 14.3 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Choline_kinase PF01633.15 EMC78702.1 - 0.11 12.0 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase HMG14_17 PF01101.13 EMC78703.1 - 2.1e-21 76.4 20.9 2.4e-21 76.2 14.5 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 Pap_E4 PF02711.9 EMC78703.1 - 3.5 8.5 5.2 3.4 8.5 3.3 1.3 1 1 0 1 1 1 0 E4 protein TT_ORF2 PF02957.10 EMC78703.1 - 6.6 7.4 7.9 7.8 7.2 5.5 1.3 1 0 0 1 1 1 0 TT viral ORF2 Prenyltransf PF01255.14 EMC78704.1 - 5.5e-83 277.4 0.0 8e-83 276.9 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zf-CCHC PF00098.18 EMC78705.1 - 8.3e-07 28.6 11.3 4.4e-05 23.2 2.1 2.3 2 0 0 2 2 2 2 Zinc knuckle CSD PF00313.17 EMC78705.1 - 2.5e-06 27.1 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC_4 PF14392.1 EMC78705.1 - 2.6e-05 23.7 10.2 0.024 14.2 0.8 2.5 2 0 0 2 2 2 2 Zinc knuckle Viral_NABP PF05515.6 EMC78705.1 - 0.087 13.1 1.9 0.13 12.5 1.3 1.3 1 0 0 1 1 1 0 Viral nucleic acid binding CusF_Ec PF11604.3 EMC78705.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF zf-CCHC_6 PF15288.1 EMC78705.1 - 0.3 10.8 7.5 4.2 7.1 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EMC78705.1 - 5.9 6.4 11.7 0.26 10.8 3.8 1.9 1 1 1 2 2 2 0 Zinc knuckle CSD PF00313.17 EMC78706.1 - 0.00039 20.1 0.2 0.001 18.7 0.1 1.7 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain SEP PF08059.8 EMC78707.1 - 9.4e-13 48.2 0.0 2.1e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EMC78707.1 - 1.3e-08 34.8 0.0 6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 UBX domain TMPIT PF07851.8 EMC78707.1 - 0.0065 15.5 0.6 0.0099 14.9 0.4 1.1 1 0 0 1 1 1 1 TMPIT-like protein WD40_alt PF14077.1 EMC78707.1 - 0.11 12.1 0.3 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif Nup54 PF13874.1 EMC78707.1 - 0.12 11.9 4.2 0.28 10.8 2.9 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Med4 PF10018.4 EMC78707.1 - 0.67 9.3 6.4 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIC PF04977.10 EMC78707.1 - 3.3 7.2 9.5 0.18 11.2 2.3 2.0 2 0 0 2 2 2 0 Septum formation initiator SH3BGR PF04908.10 EMC78708.1 - 2e-38 130.3 0.1 2.3e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EMC78708.1 - 3.5e-07 30.0 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Reo_sigmaC PF04582.7 EMC78709.1 - 0.15 11.1 14.8 0.13 11.4 2.4 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein ATP-synt_Eps PF04627.8 EMC78709.1 - 1.1 8.8 2.9 1.3 8.6 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain FAM110_N PF14161.1 EMC78712.1 - 6e-15 55.4 0.6 1.7e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Centrosome-associated N terminus Cation_efflux PF01545.16 EMC78713.1 - 1.1e-48 165.7 6.8 1.2e-48 165.6 4.7 1.0 1 0 0 1 1 1 1 Cation efflux family Chromate_transp PF02417.10 EMC78713.1 - 0.59 9.7 8.5 0.54 9.8 1.9 2.2 1 1 1 2 2 2 0 Chromate transporter CDV3 PF15359.1 EMC78715.1 - 2.1e-61 205.6 6.3 2.8e-61 205.2 4.4 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 BRCT PF00533.21 EMC78716.1 - 7.1e-80 263.2 0.6 7.3e-16 58.0 0.1 8.9 9 0 0 9 9 9 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMC78716.1 - 9.6e-61 201.5 9.4 6.7e-22 77.1 0.8 7.0 7 0 0 7 7 7 6 twin BRCT domain Lin-8 PF03353.10 EMC78716.1 - 1.8 7.7 6.9 3.8 6.7 4.8 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist 7tm_1 PF00001.16 EMC78717.1 - 2.2e-52 177.7 28.7 3.5e-28 98.4 8.6 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78717.1 - 3.5e-06 26.3 21.8 7.9e-05 21.9 15.1 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4239 PF14023.1 EMC78717.1 - 2.5 7.4 9.0 0.14 11.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) 7tm_1 PF00001.16 EMC78718.1 - 2.3e-57 194.0 21.8 2.7e-57 193.8 15.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78718.1 - 1.8e-08 33.8 22.4 2.3e-08 33.5 15.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC78718.1 - 0.081 12.7 16.7 0.033 13.9 8.0 2.7 1 1 1 2 2 2 0 Olfactory receptor 7tm_1 PF00001.16 EMC78719.1 - 9.7e-47 159.2 17.8 1.1e-46 159.0 12.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC78720.1 - 2.8e-48 164.2 21.6 4.5e-48 163.6 15.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78720.1 - 0.0015 17.7 21.7 0.0021 17.2 15.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MCLC PF05934.6 EMC78720.1 - 2.9 6.0 5.3 0.4 8.9 0.6 1.7 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) MIF4G PF02854.14 EMC78721.1 - 3.2e-27 95.3 1.9 3.2e-27 95.3 1.3 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EMC78721.1 - 0.0027 17.3 0.0 0.0088 15.7 0.0 1.9 1 0 0 1 1 1 1 MA3 domain CAF1-p150_C2 PF15539.1 EMC78721.1 - 1.4 7.9 4.4 9.1 5.2 0.0 2.2 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term UQ_con PF00179.21 EMC78722.1 - 3.1e-46 156.2 0.0 4.8e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC78722.1 - 0.00057 19.6 0.0 0.00087 19.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC78722.1 - 0.0019 18.1 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC78722.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Herpes_LMP2 PF07415.6 EMC78722.1 - 3.2 6.2 5.3 4.7 5.6 3.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Integrin_alpha2 PF08441.7 EMC78723.1 - 5.2e-83 279.4 2.5 1.6e-82 277.8 0.7 1.9 1 1 1 2 2 2 1 Integrin alpha FG-GAP PF01839.18 EMC78723.1 - 5.8e-18 64.0 6.9 1.8e-07 30.6 0.0 3.8 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 EMC78723.1 - 3.3e-11 43.3 6.1 5.4e-08 33.0 0.1 2.8 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 EMC78723.1 - 0.0009 18.8 0.5 0.0019 17.8 0.4 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region Spp-24 PF07448.6 EMC78724.1 - 5.8e-22 78.1 0.3 9.1e-22 77.5 0.2 1.3 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) Cathelicidins PF00666.12 EMC78724.1 - 2.9e-06 27.3 0.0 4.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Cathelicidin Cystatin PF00031.16 EMC78724.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain Arf PF00025.16 EMC78725.1 - 7.3e-62 207.6 0.0 8.2e-62 207.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC78725.1 - 1.6e-15 56.8 0.0 2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC78725.1 - 4.8e-11 42.1 0.0 7.4e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC78725.1 - 2.4e-10 40.9 0.0 3.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EMC78725.1 - 8.1e-08 31.3 0.1 1.9e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 EMC78725.1 - 9.2e-06 25.2 0.0 5.6e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC78725.1 - 1e-05 25.4 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC78725.1 - 0.00086 18.5 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.13 EMC78725.1 - 0.054 12.5 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SH3_2 PF07653.12 EMC78726.1 - 3.5e-22 77.6 0.1 1.9e-10 40.0 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.1 EMC78726.1 - 2.1e-12 46.3 0.5 5e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC78726.1 - 2e-10 39.9 0.6 1.2e-09 37.3 0.0 2.6 2 1 0 2 2 2 1 SH3 domain ZU5 PF00791.15 EMC78726.1 - 4.2e-06 26.3 0.1 1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 ZU5 domain SH3_3 PF08239.6 EMC78726.1 - 0.38 10.9 2.9 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain UDPGT PF00201.13 EMC78727.1 - 3.7e-189 629.4 0.0 4.4e-189 629.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMC78727.1 - 9.5e-07 28.6 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EMC78727.1 - 3.2e-05 23.2 0.0 0.0015 17.8 0.0 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 1 Prominin PF05478.6 EMC78727.1 - 0.00098 16.7 0.2 0.0013 16.3 0.1 1.2 1 0 0 1 1 1 1 Prominin RhoGAP PF00620.22 EMC78728.1 - 5.3e-15 55.3 3.7 3.9e-07 29.8 0.1 5.0 3 1 2 5 5 5 4 RhoGAP domain Trypan_PARP PF05887.6 EMC78729.1 - 0.0017 18.1 26.5 0.0025 17.6 18.4 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4045 PF13254.1 EMC78729.1 - 0.033 13.4 23.9 0.041 13.1 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.7 EMC78729.1 - 0.18 11.6 35.0 0.23 11.3 24.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gag_spuma PF03276.9 EMC78729.1 - 0.27 9.4 10.2 0.32 9.2 7.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF2201_N PF13203.1 EMC78729.1 - 0.29 10.2 18.5 0.43 9.7 12.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EMC78729.1 - 0.33 8.9 27.8 0.39 8.7 19.3 1.2 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 EMC78729.1 - 0.38 10.6 24.8 0.54 10.1 17.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 EMC78729.1 - 0.41 9.2 19.9 0.55 8.8 13.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pilt PF15453.1 EMC78729.1 - 0.46 10.1 21.2 0.57 9.8 14.7 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SprA-related PF12118.3 EMC78729.1 - 0.72 9.1 29.4 0.94 8.7 20.4 1.1 1 0 0 1 1 1 0 SprA-related family Paf1 PF03985.8 EMC78729.1 - 1 8.0 36.2 1.3 7.6 25.1 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 EMC78729.1 - 3 6.9 24.2 4 6.4 16.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 EMC78729.1 - 3.4 6.6 15.5 4.4 6.2 10.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpb1_5 PF04998.12 EMC78729.1 - 4 6.6 14.7 4.9 6.3 10.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CDC27 PF09507.5 EMC78729.1 - 4.3 6.4 47.2 6.2 5.9 32.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.2 EMC78729.1 - 6.3 4.3 18.1 6.8 4.2 12.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CT47 PF15623.1 EMC78729.1 - 6.9 6.3 35.5 3.6 7.2 23.0 1.7 2 0 0 2 2 2 0 Cancer/testis gene family 47 Parvo_coat PF00740.13 EMC78729.1 - 7.6 5.3 10.4 10 4.9 7.2 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FLO_LFY PF01698.11 EMC78729.1 - 7.9 5.2 29.9 12 4.6 20.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein zf-C3HC4_3 PF13920.1 EMC78730.1 - 9e-11 41.2 6.4 1.5e-10 40.5 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC78730.1 - 1.5e-09 37.3 9.2 3e-09 36.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC78730.1 - 1.6e-09 37.4 10.9 1.6e-09 37.4 7.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC78730.1 - 2.6e-08 33.7 9.8 4.9e-08 32.8 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC78730.1 - 2e-06 27.7 7.8 4.1e-06 26.8 5.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC78730.1 - 2.7e-06 27.0 8.0 5.1e-06 26.1 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC78730.1 - 0.0016 18.3 9.1 0.0042 16.9 6.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMC78730.1 - 0.0064 16.3 5.5 0.013 15.3 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EMC78730.1 - 0.0076 15.9 8.0 0.017 14.8 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 EMC78730.1 - 0.0076 15.6 0.3 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-MIZ PF02891.15 EMC78730.1 - 0.042 13.3 10.1 0.056 12.9 0.1 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EMC78730.1 - 0.05 13.1 9.6 0.29 10.7 6.9 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Sec23_Sec24 PF04810.10 EMC78730.1 - 0.11 12.1 2.8 0.28 10.7 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF4496 PF14908.1 EMC78731.1 - 4.6e-17 62.2 0.1 5.3e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) UPF0146 PF03686.8 EMC78731.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Rad17 PF03215.10 EMC78732.1 - 1.3e-172 575.1 0.1 1.5e-172 574.9 0.1 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EMC78732.1 - 1.7e-06 28.1 0.0 4.7e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EMC78732.1 - 1.2e-05 25.4 0.0 2.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC78732.1 - 2e-05 24.7 0.0 5.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC78732.1 - 0.0001 21.4 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMC78732.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMC78732.1 - 0.00024 21.4 0.0 0.00067 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC78732.1 - 0.0012 19.6 0.0 0.0031 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC78732.1 - 0.003 17.2 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EMC78732.1 - 0.0038 16.8 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EMC78732.1 - 0.0075 16.1 0.0 0.019 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMC78732.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC78732.1 - 0.017 15.3 0.1 0.091 12.9 0.0 2.3 2 1 0 2 2 2 0 RNA helicase DMA PF03474.9 EMC78732.1 - 0.03 14.1 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 DMRTA motif Zeta_toxin PF06414.7 EMC78732.1 - 0.042 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EMC78732.1 - 0.063 12.9 0.3 0.38 10.3 0.2 2.4 2 1 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EMC78732.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EMC78732.1 - 0.094 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EMC78732.1 - 0.098 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EMC78732.1 - 0.1 12.1 0.7 0.26 10.8 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMC78732.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC78733.1 - 3e-23 82.5 0.1 4.8e-23 81.8 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC78733.1 - 4.2e-12 46.9 0.1 9.4e-12 45.8 0.0 1.5 1 1 1 2 2 2 1 AAA domain SKI PF01202.17 EMC78733.1 - 2.4e-05 24.2 1.4 0.0081 16.0 0.1 2.7 2 1 1 3 3 3 2 Shikimate kinase AAA PF00004.24 EMC78733.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMC78733.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 EMC78733.1 - 0.11 12.3 0.1 0.45 10.4 0.1 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family EHN PF06441.7 EMC78734.1 - 0.044 13.7 0.8 0.044 13.7 0.6 2.2 3 0 0 3 3 3 0 Epoxide hydrolase N terminus MerR-DNA-bind PF09278.6 EMC78734.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.3 4 0 0 4 4 4 0 MerR, DNA binding Uds1 PF15456.1 EMC78734.1 - 2.8 7.9 21.4 2.1 8.3 5.8 3.4 2 1 1 3 3 3 0 Up-regulated During Septation GAS PF13851.1 EMC78734.1 - 6.9 5.8 32.0 0.057 12.6 2.2 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DMPK_coil PF08826.5 EMC78734.1 - 7.2 6.5 24.5 0.79 9.6 0.5 4.8 5 0 0 5 5 5 0 DMPK coiled coil domain like DUF3480 PF11979.3 EMC78735.1 - 1.3e-153 510.8 0.1 2.9e-153 509.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3480) FYVE PF01363.16 EMC78735.1 - 9.5e-20 70.2 15.3 2.8e-19 68.7 10.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger DUF2181 PF10223.4 EMC78736.1 - 7.5e-75 251.4 0.4 5.9e-47 160.0 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2181) Ank_2 PF12796.2 EMC78737.1 - 2.4e-31 107.9 0.9 4.7e-19 68.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC78737.1 - 3.5e-20 70.7 0.0 5.7e-08 32.1 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EMC78737.1 - 1.3e-19 70.1 0.1 2.4e-06 27.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC78737.1 - 5.1e-15 55.1 0.1 2.2e-08 34.0 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC78737.1 - 1.1e-14 53.0 0.0 2e-05 24.4 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat DHFR_1 PF00186.14 EMC78738.1 - 1e-27 96.7 0.0 1.2e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase MutS_I PF01624.15 EMC78739.1 - 1.5e-32 111.9 0.2 2.2e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMC78739.1 - 8e-12 45.3 0.3 3.2e-11 43.4 0.0 2.1 3 0 0 3 3 3 1 MutS domain II MutS_V PF00488.16 EMC78740.1 - 2.6e-76 256.1 0.1 5.6e-76 255.0 0.0 1.5 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC78740.1 - 4e-37 127.9 0.7 7.9e-37 127.0 0.3 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EMC78740.1 - 4.2e-11 43.0 0.1 2.8e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EMC78740.1 - 3.6e-07 30.2 0.1 1.5e-06 28.3 0.1 2.1 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.1 EMC78740.1 - 0.037 14.1 0.2 0.32 11.1 0.0 2.6 4 0 0 4 4 4 0 AAA domain Guanylate_cyc PF00211.15 EMC78740.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain NPV_P10 PF05531.7 EMC78740.1 - 0.32 11.2 3.7 5.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RasGEF PF00617.14 EMC78741.1 - 2.2e-51 174.2 0.1 5.9e-51 172.8 0.1 1.8 1 0 0 1 1 1 1 RasGEF domain RhoGEF PF00621.15 EMC78741.1 - 2.7e-33 115.3 2.4 2.7e-33 115.3 1.7 2.2 2 0 0 2 2 2 1 RhoGEF domain RasGEF_N PF00618.15 EMC78741.1 - 1.3e-22 79.8 0.9 4.2e-16 58.9 0.1 3.4 3 0 0 3 3 3 2 RasGEF N-terminal motif PH PF00169.24 EMC78741.1 - 1.5e-06 28.3 0.0 0.018 15.2 0.0 3.1 3 0 0 3 3 3 2 PH domain IQ PF00612.22 EMC78741.1 - 0.0058 16.1 1.7 0.014 14.9 1.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif ATP-gua_Ptrans PF00217.14 EMC78742.1 - 1.7e-102 341.8 0.0 2.1e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 EMC78742.1 - 2e-33 114.3 0.0 3.2e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain GD_AH_C PF04295.8 EMC78742.1 - 0.15 10.7 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus zf-CCHC PF00098.18 EMC78743.1 - 3.7e-17 61.3 23.8 1.9e-06 27.5 0.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EMC78743.1 - 1.9e-06 27.4 23.3 0.021 14.5 0.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EMC78743.1 - 7.9e-05 22.0 15.3 0.11 11.9 0.5 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.1 EMC78743.1 - 0.016 14.7 0.2 0.016 14.7 0.1 2.9 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 EMC78743.1 - 0.056 13.3 0.4 0.056 13.3 0.3 3.8 2 1 3 5 5 5 0 Eukaryotic translation initiation factor 3 subunit G Prim_Zn_Ribbon PF08273.7 EMC78743.1 - 0.31 11.1 11.9 2.3 8.3 0.1 3.8 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase zf-CCHC_3 PF13917.1 EMC78743.1 - 3.1 7.6 15.3 7.2 6.4 0.5 4.2 2 1 2 4 4 4 0 Zinc knuckle XPA_N PF01286.13 EMC78743.1 - 5.4 6.7 6.7 39 4.0 0.1 3.5 4 0 0 4 4 4 0 XPA protein N-terminal START PF01852.14 EMC78744.1 - 2.4e-18 66.2 0.1 2.9e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.4 EMC78744.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport 4HBT PF03061.17 EMC78745.1 - 4.5e-25 87.5 0.3 5.1e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily SSDP PF04503.8 EMC78746.1 - 1.2e-113 379.7 57.6 5.5e-111 371.0 40.0 2.0 1 1 0 1 1 1 1 Single-stranded DNA binding protein, SSDP Autophagy_act_C PF03987.10 EMC78747.1 - 1.4e-20 73.2 0.3 2.2e-20 72.5 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosom_S12_S23 PF00164.20 EMC78748.1 - 2.8e-42 142.9 1.1 3.5e-42 142.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ATP-synt_S1 PF05827.7 EMC78749.1 - 2.2e-08 33.7 0.2 2.7e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.12 EMC78749.1 - 8.7e-07 28.3 0.2 1.1e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) MtrG PF04210.8 EMC78749.1 - 6.6 6.4 5.6 26 4.5 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G VMA21 PF09446.5 EMC78750.1 - 4.2e-10 39.3 3.2 4.6e-10 39.2 2.2 1.0 1 0 0 1 1 1 1 VMA21-like domain Phage_holin_6 PF10746.4 EMC78750.1 - 0.089 12.5 0.2 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 Phage holin family 6 ABC_membrane_3 PF13748.1 EMC78750.1 - 0.093 11.7 0.1 0.098 11.6 0.1 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region PAS_11 PF14598.1 EMC78751.1 - 6.7e-26 90.4 1.9 1.1e-21 76.8 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 EMC78751.1 - 4.2e-18 65.2 0.1 5.8e-15 55.1 0.1 2.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 EMC78751.1 - 1.8e-11 43.7 0.0 3.8e-08 33.0 0.0 3.3 4 0 0 4 4 4 2 PAS fold HLH PF00010.21 EMC78751.1 - 6.2e-08 32.2 0.6 1.3e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EMC78751.1 - 9e-06 26.0 0.0 0.0002 21.6 0.0 2.9 2 1 1 3 3 3 1 PAS domain PAS_4 PF08448.5 EMC78751.1 - 0.081 12.9 0.1 0.61 10.1 0.0 2.5 3 0 0 3 3 3 0 PAS fold Rotavirus_VP1 PF12289.3 EMC78751.1 - 0.13 11.8 0.9 17 5.1 0.0 3.3 3 0 0 3 3 3 0 Rotavirus VP1 structural protein RabGAP-TBC PF00566.13 EMC78752.1 - 7.3e-46 156.3 2.4 1.3e-45 155.4 0.0 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.15 EMC78752.1 - 1.2e-29 101.5 0.7 4.6e-15 54.8 0.1 2.6 2 0 0 2 2 2 2 GRAM domain PA PF02225.17 EMC78753.1 - 4.1e-11 42.4 0.0 6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EMC78753.1 - 2.4e-06 27.5 6.1 4.7e-06 26.6 4.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMC78753.1 - 3.1e-05 23.7 11.1 3.1e-05 23.7 7.7 1.9 2 1 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EMC78753.1 - 0.0024 17.6 4.6 0.005 16.6 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SieB PF14163.1 EMC78753.1 - 0.034 13.7 0.2 0.056 13.0 0.2 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B zf-C3HC4_2 PF13923.1 EMC78753.1 - 0.042 13.8 9.3 0.13 12.2 6.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC78753.1 - 0.18 11.4 8.8 0.47 10.1 6.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC78753.1 - 0.37 10.5 9.2 0.66 9.6 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) tRNA_anti-codon PF01336.20 EMC78755.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4539 PF15072.1 EMC78755.1 - 0.085 12.5 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Pkinase PF00069.20 EMC78756.1 - 3.6e-65 219.6 0.0 7.5e-65 218.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.17 EMC78756.1 - 6.9e-54 183.1 0.0 1.2e-53 182.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 EMC78756.1 - 1.1e-45 155.7 0.0 1.8e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC78756.1 - 4.1e-05 22.6 0.0 0.00012 21.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC78756.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family TIR PF01582.15 EMC78757.1 - 3.6e-30 104.2 0.2 9e-30 102.9 0.1 1.8 2 0 0 2 2 2 1 TIR domain I-set PF07679.11 EMC78757.1 - 6.5e-21 73.9 0.0 8.3e-06 25.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78757.1 - 4.8e-17 61.8 0.0 1.4e-05 25.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC78757.1 - 1.5e-13 51.0 0.0 6.5e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC78757.1 - 2e-12 47.0 0.0 0.0003 20.8 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC78757.1 - 6.6e-12 45.3 0.0 0.0097 15.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin V-set domain TIR_2 PF13676.1 EMC78757.1 - 6.1e-05 23.1 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 TIR domain V-set_CD47 PF08204.6 EMC78757.1 - 0.00022 20.9 2.2 0.062 13.0 0.0 3.5 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain OAR PF03826.12 EMC78758.1 - 3.9e-10 38.8 1.3 6.8e-10 38.1 0.9 1.4 1 0 0 1 1 1 1 OAR domain PmbA_TldD PF01523.11 EMC78759.1 - 0.036 13.3 3.5 0.057 12.6 2.4 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Hex_IIIa PF02455.11 EMC78759.1 - 0.17 10.5 8.2 0.25 9.9 5.7 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Herpes_capsid PF06112.6 EMC78759.1 - 0.26 11.2 19.3 0.78 9.7 13.4 1.9 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SOBP PF15279.1 EMC78759.1 - 0.31 11.3 9.6 0.47 10.7 6.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 EMC78759.1 - 0.45 9.8 20.4 0.44 9.8 13.4 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 EMC78759.1 - 1.1 9.0 8.5 1.7 8.4 5.9 1.3 1 0 0 1 1 1 0 DDHD domain HCaRG PF07258.9 EMC78760.1 - 1.2e-34 119.4 0.1 1.3e-34 119.3 0.1 1.0 1 0 0 1 1 1 1 HCaRG protein DUF3789 PF12664.2 EMC78761.1 - 3.1e-10 39.2 34.5 13 5.2 0.0 13.1 1 1 13 14 14 14 13 Protein of unknown function (DUF3789) Yae1_N PF09811.4 EMC78761.1 - 0.0049 16.3 27.5 6.1 6.4 0.7 5.7 1 1 7 8 8 8 8 Essential protein Yae1, N terminal DUF2823 PF11034.3 EMC78761.1 - 0.068 13.2 20.8 8.5 6.5 1.0 4.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2823) DUF3941 PF13081.1 EMC78761.1 - 2.1 8.3 74.5 8.3 6.4 0.7 11.7 1 1 9 10 10 10 0 Domain of unknown function (DUF3941) Cyt-b5 PF00173.23 EMC78763.1 - 0.0039 16.9 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Med31 PF05669.7 EMC78764.1 - 0.047 13.4 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 SOH1 DUF4164 PF13747.1 EMC78764.1 - 0.22 11.6 2.3 0.29 11.2 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Dynein_light PF01221.13 EMC78765.1 - 1.7e-29 101.6 0.7 1.8e-29 101.5 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Viral_DNA_bi PF02236.12 EMC78765.1 - 0.014 15.5 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain UCH PF00443.24 EMC78765.1 - 0.014 14.5 0.1 0.016 14.3 0.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Omptin PF01278.15 EMC78765.1 - 0.068 12.2 0.1 0.068 12.2 0.1 1.1 1 0 0 1 1 1 0 Omptin family Sigma70_r2 PF04542.9 EMC78765.1 - 0.12 12.0 0.1 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Sigma-70 region 2 Dynein_light PF01221.13 EMC78766.1 - 1.2e-35 121.3 0.5 1.3e-35 121.2 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.24 EMC78766.1 - 0.031 13.3 0.1 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Omptin PF01278.15 EMC78766.1 - 0.052 12.6 0.1 0.054 12.5 0.1 1.1 1 0 0 1 1 1 0 Omptin family TraH PF06122.6 EMC78766.1 - 0.057 12.2 0.1 0.059 12.1 0.0 1.0 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein NMT_C PF02799.10 EMC78766.1 - 0.074 12.4 0.1 0.09 12.1 0.1 1.0 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Mito_carr PF00153.22 EMC78767.1 - 8.6e-58 192.0 0.4 5.9e-27 93.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4410 PF14366.1 EMC78768.1 - 0.46 10.2 2.7 0.81 9.4 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4410) UQ_con PF00179.21 EMC78769.1 - 5.1e-40 136.1 0.1 5.7e-40 135.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC78769.1 - 3.8e-06 26.6 0.0 4.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC78769.1 - 0.00084 19.2 0.2 0.0013 18.6 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EMC78769.1 - 0.0068 16.0 0.1 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain G-patch PF01585.18 EMC78770.1 - 3.4e-15 55.5 3.0 9.2e-15 54.1 2.1 1.8 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.20 EMC78770.1 - 9.2e-13 48.5 6.9 2.8e-05 24.5 0.1 4.4 4 0 0 4 4 4 3 Double-stranded RNA binding motif R3H PF01424.17 EMC78770.1 - 2.1e-08 33.7 0.1 5.1e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EMC78770.1 - 1.5e-05 24.7 0.8 5.3e-05 22.9 0.5 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3469 PF11952.3 EMC78770.1 - 0.015 15.0 1.2 0.24 11.1 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3469) Septin PF00735.13 EMC78771.1 - 6.6e-96 320.6 0.4 6.6e-96 320.6 0.3 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMC78771.1 - 0.00078 19.3 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC78771.1 - 0.00097 19.1 0.6 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC78771.1 - 0.0062 16.6 2.7 0.0085 16.2 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMC78771.1 - 0.017 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EMC78771.1 - 0.023 14.1 1.7 1.5 8.2 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EMC78771.1 - 0.031 13.7 1.2 0.076 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 EMC78771.1 - 0.033 14.6 2.5 0.039 14.4 0.1 2.4 2 1 0 2 2 2 0 Miro-like protein IMD PF08397.6 EMC78771.1 - 0.04 13.2 14.3 0.081 12.2 9.9 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF4478 PF14793.1 EMC78771.1 - 0.051 13.1 0.5 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4478) FtsK_SpoIIIE PF01580.13 EMC78771.1 - 0.053 12.9 2.1 0.9 8.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Fzo_mitofusin PF04799.8 EMC78771.1 - 0.18 11.1 8.3 0.26 10.6 5.1 1.7 2 0 0 2 2 2 0 fzo-like conserved region AAA_11 PF13086.1 EMC78771.1 - 0.33 10.4 5.5 0.58 9.6 3.8 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EMC78771.1 - 0.61 9.8 8.1 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 IncA PF04156.9 EMC78771.1 - 0.62 9.6 12.0 1.1 8.8 8.3 1.3 1 0 0 1 1 1 0 IncA protein ABC_tran PF00005.22 EMC78771.1 - 2.6 8.3 6.2 0.33 11.2 0.1 2.4 2 2 0 2 2 2 0 ABC transporter Ribosomal_L39 PF00832.15 EMC78772.1 - 6.6e-24 83.1 10.1 7.4e-24 82.9 7.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Smg4_UPF3 PF03467.10 EMC78773.1 - 1e-37 129.7 3.5 1e-37 129.7 2.5 3.2 2 1 0 3 3 3 1 Smg-4/UPF3 family Mg_trans_NIPA PF05653.9 EMC78775.1 - 4.9e-75 252.2 5.6 5.6e-75 252.0 3.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMC78775.1 - 2e-10 40.8 1.7 2e-10 40.8 1.2 2.1 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC78775.1 - 1.1e-08 35.1 8.3 3.4e-08 33.5 2.7 2.2 2 0 0 2 2 2 1 EamA-like transporter family AgrB PF04647.10 EMC78775.1 - 0.00056 19.0 0.6 0.00081 18.4 0.4 1.2 1 0 0 1 1 1 1 Accessory gene regulator B Nuc_sug_transp PF04142.10 EMC78775.1 - 0.043 12.9 3.0 0.12 11.4 0.4 2.0 1 1 1 2 2 2 0 Nucleotide-sugar transporter DUF4064 PF13273.1 EMC78775.1 - 0.16 12.0 2.9 0.18 11.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) YrhK PF14145.1 EMC78775.1 - 1.8 8.3 5.3 1.4 8.6 0.1 3.0 3 0 0 3 3 3 0 YrhK-like protein DUF1295 PF06966.7 EMC78775.1 - 2.4 7.4 4.2 1.6 7.9 1.2 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1295) TAFII55_N PF04658.8 EMC78776.1 - 3.5e-51 172.9 0.8 3.5e-51 172.9 0.5 1.9 2 1 0 2 2 2 1 TAFII55 protein conserved region Mo25 PF08569.6 EMC78776.1 - 0.055 12.4 6.5 0.11 11.5 4.5 1.4 1 0 0 1 1 1 0 Mo25-like DoxX_2 PF13564.1 EMC78778.1 - 2.7e-08 33.6 2.0 4.6e-08 32.9 1.4 1.3 1 1 0 1 1 1 1 DoxX-like family DUF4131 PF13567.1 EMC78778.1 - 0.0089 15.4 0.2 0.096 12.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) DUF843 PF05814.6 EMC78778.1 - 0.15 11.8 0.2 0.15 11.8 0.2 1.7 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) HCV_NS2 PF01538.13 EMC78778.1 - 0.15 11.4 1.6 0.2 11.0 1.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DUF308 PF03729.8 EMC78778.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.1 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) NS3_envE PF02723.9 EMC78778.1 - 7.7 6.5 6.3 6 6.8 0.5 2.6 2 1 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E DKCLD PF08068.7 EMC78779.1 - 7.7e-23 80.1 0.6 4.5e-22 77.7 0.0 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EMC78779.1 - 1.3e-21 77.2 5.6 4.3e-20 72.3 0.1 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EMC78779.1 - 3.5e-14 52.2 0.5 8.2e-14 51.0 0.4 1.7 1 0 0 1 1 1 1 PUA domain Guanylate_kin PF00625.16 EMC78780.1 - 3.2e-59 199.4 0.2 5.6e-59 198.6 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.19 EMC78780.1 - 2.8e-19 69.0 3.3 3.7e-19 68.6 0.7 2.1 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 EMC78780.1 - 1.3e-10 40.5 0.0 3.1e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC78780.1 - 1.4e-08 34.0 0.9 6.5e-08 31.8 0.6 2.1 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC78780.1 - 6.8e-07 28.7 0.0 1.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.1 EMC78780.1 - 1.6e-05 24.7 0.3 0.0001 22.1 0.1 2.2 2 0 0 2 2 2 1 PDZ domain DUF258 PF03193.11 EMC78780.1 - 0.00077 18.6 0.0 0.0019 17.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Tricorn_PDZ PF14685.1 EMC78780.1 - 0.0033 17.1 0.8 0.15 11.8 0.1 3.1 3 1 0 3 3 3 1 Tricorn protease PDZ domain MMR_HSR1 PF01926.18 EMC78780.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EMC78780.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein F5_F8_type_C PF00754.20 EMC78781.1 - 7.2e-56 187.5 5.7 1.2e-27 96.2 0.4 2.6 2 0 0 2 2 2 2 F5/8 type C domain Cu-oxidase_3 PF07732.10 EMC78781.1 - 1.2e-16 60.5 0.0 0.00012 21.7 0.0 4.8 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC78781.1 - 4.3e-13 48.9 6.3 2.3e-08 33.6 0.8 4.9 6 0 0 6 6 6 3 Multicopper oxidase FUN14 PF04930.10 EMC78782.1 - 5.6e-33 113.1 4.7 6.8e-33 112.9 3.2 1.1 1 0 0 1 1 1 1 FUN14 family SH3BGR PF04908.10 EMC78782.1 - 0.066 13.1 0.0 10 6.1 0.1 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF4419 PF14388.1 EMC78782.1 - 0.13 11.5 0.3 0.32 10.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4419) DUF1903 PF08991.5 EMC78783.1 - 5.6e-13 48.8 5.3 6.3e-13 48.6 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) DUF1068 PF06364.7 EMC78783.1 - 0.11 12.1 1.6 0.12 11.9 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) TCL1_MTCP1 PF01840.12 EMC78784.1 - 1.6e-20 72.8 0.0 1.7e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 TCL1/MTCP1 family JAB PF01398.16 EMC78785.1 - 2e-19 69.3 1.7 2e-19 69.3 1.2 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMC78785.1 - 0.00025 20.5 0.1 0.00051 19.5 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain bZIP_2 PF07716.10 EMC78785.1 - 0.34 10.7 9.1 0.56 10.0 6.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper SprT-like PF10263.4 EMC78786.1 - 7.3e-16 58.2 0.0 2.3e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 SprT-like family Glyco_transf_41 PF13844.1 EMC78787.1 - 5.3e-274 908.2 0.0 7e-274 907.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.23 EMC78787.1 - 7.7e-98 316.4 27.4 2.2e-10 39.6 0.2 13.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.1 EMC78787.1 - 3e-93 305.5 35.3 2.4e-16 59.1 0.4 8.8 7 2 2 9 9 8 8 TPR repeat TPR_17 PF13431.1 EMC78787.1 - 3.6e-75 242.0 27.5 5.1e-07 29.3 0.0 13.9 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_2 PF07719.12 EMC78787.1 - 9.7e-74 237.4 27.9 2.3e-08 33.3 0.3 13.2 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 EMC78787.1 - 5.5e-65 215.2 39.1 6.4e-14 51.6 0.2 7.9 1 1 9 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EMC78787.1 - 9.1e-55 182.3 19.3 3.3e-10 40.3 0.2 8.4 5 2 3 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78787.1 - 3.4e-54 176.3 16.5 1.3e-05 25.3 0.1 12.5 4 2 8 12 12 12 11 Tetratricopeptide repeat TPR_8 PF13181.1 EMC78787.1 - 1.9e-52 171.1 9.0 1.1e-05 24.8 0.1 12.3 12 0 0 12 12 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 EMC78787.1 - 1.1e-44 146.6 17.8 2.4e-05 23.7 0.0 13.2 13 1 1 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 EMC78787.1 - 2.9e-39 133.2 17.9 5.2e-06 26.7 0.3 9.5 3 3 6 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 EMC78787.1 - 6.7e-26 89.4 42.9 1.5e-05 24.7 0.2 12.3 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 EMC78787.1 - 2.3e-20 71.5 13.0 0.21 12.1 0.0 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 EMC78787.1 - 2e-15 56.3 15.9 0.015 15.1 0.0 6.7 4 2 3 7 7 7 5 Tetratricopeptide repeat NARP1 PF12569.3 EMC78787.1 - 1.7e-14 53.5 5.9 0.0014 17.4 0.0 5.8 1 1 4 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 EMC78787.1 - 4.4e-14 51.3 10.3 1.3 9.6 0.2 9.4 9 0 0 9 9 8 1 Tetratricopeptide repeat MIT PF04212.13 EMC78787.1 - 3.3e-09 36.5 21.5 0.024 14.4 0.0 8.9 7 2 3 10 10 8 3 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 EMC78787.1 - 4.4e-08 32.5 7.7 0.00032 19.8 0.5 4.6 1 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC78787.1 - 1.2e-07 31.7 23.2 0.00032 20.7 0.8 5.9 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EMC78787.1 - 3.6e-06 26.6 1.2 1.5 8.7 0.0 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat SNAP PF14938.1 EMC78787.1 - 8.8e-06 25.0 14.5 0.013 14.6 1.6 4.9 2 1 2 5 5 5 2 Soluble NSF attachment protein, SNAP EST1_DNA_bind PF10373.4 EMC78787.1 - 2.7e-05 23.5 15.3 0.15 11.2 0.3 5.2 3 1 2 5 5 5 2 Est1 DNA/RNA binding domain TPR_21 PF09976.4 EMC78787.1 - 0.00018 21.4 12.3 0.33 10.8 0.0 5.4 5 2 0 5 5 4 2 Tetratricopeptide repeat FAT PF02259.18 EMC78787.1 - 0.00035 19.6 2.6 1.5 7.7 0.1 5.1 2 2 1 3 3 3 1 FAT domain TPR_5 PF12688.2 EMC78787.1 - 0.006 16.6 5.1 1.7 8.7 0.1 4.2 3 2 2 5 5 4 2 Tetratrico peptide repeat SHNi-TPR PF10516.4 EMC78787.1 - 0.0071 15.5 3.3 27 4.1 0.0 5.4 7 0 0 7 7 7 0 SHNi-TPR DUF3366 PF11846.3 EMC78787.1 - 0.0086 15.9 17.2 0.043 13.6 0.1 4.7 4 1 1 6 6 4 2 Domain of unknown function (DUF3366) Tcf25 PF04910.9 EMC78787.1 - 0.013 14.4 0.5 0.04 12.8 0.1 2.0 2 0 0 2 2 2 0 Transcriptional repressor TCF25 RPN7 PF10602.4 EMC78787.1 - 0.02 14.2 10.1 20 4.4 0.1 6.7 5 2 5 10 10 9 0 26S proteasome subunit RPN7 DUF627 PF04781.7 EMC78787.1 - 0.023 14.3 0.8 6.3 6.4 0.0 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.1 EMC78787.1 - 0.072 12.9 0.6 1 9.3 0.0 3.3 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.7 EMC78787.1 - 0.079 12.5 0.3 33 4.0 0.0 3.6 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.1 EMC78787.1 - 0.13 12.3 13.4 1.9 8.6 0.2 6.2 4 2 2 7 7 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EMC78787.1 - 0.95 9.6 5.5 3.9 7.6 0.2 3.9 4 2 0 4 4 4 0 Alkyl sulfatase dimerisation BTAD PF03704.12 EMC78787.1 - 2 8.7 16.9 3.9 7.7 0.6 5.5 3 2 2 6 6 6 0 Bacterial transcriptional activator domain DUF3591 PF12157.3 EMC78788.1 - 9.8e-157 521.9 0.0 1.3e-155 518.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EMC78788.1 - 3.4e-45 151.8 3.3 1.3e-22 79.4 0.5 3.0 2 0 0 2 2 2 2 Bromodomain zf-CCHC_6 PF15288.1 EMC78788.1 - 2.8e-15 55.6 0.3 7.8e-15 54.2 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle TBP-binding PF09247.6 EMC78788.1 - 1.4e-05 25.2 0.2 4.5e-05 23.5 0.1 2.0 1 0 0 1 1 1 1 TATA box-binding protein binding Ras PF00071.17 EMC78789.1 - 1.6e-55 186.9 0.0 1.9e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC78789.1 - 1.4e-16 61.0 0.0 2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC78789.1 - 1.3e-09 37.5 0.0 1.9e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC78789.1 - 0.017 14.2 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3799 PF12684.2 EMC78789.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) MMR_HSR1 PF01926.18 EMC78789.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase CHORD PF04968.7 EMC78790.1 - 2.3e-54 181.5 21.5 2.3e-28 98.2 3.4 2.7 3 0 0 3 3 3 2 CHORD CS PF04969.11 EMC78790.1 - 1.4e-14 54.4 0.4 2.2e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 CS domain zf-tcix PF14952.1 EMC78790.1 - 0.067 12.5 3.6 4.3 6.7 0.5 2.7 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Connexin PF00029.14 EMC78791.1 - 7e-49 164.3 0.1 1.4e-48 163.3 0.1 1.5 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC78791.1 - 2.7e-34 116.8 1.1 6e-34 115.6 0.8 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin PF00029.14 EMC78792.1 - 9.9e-49 163.8 1.0 9.9e-49 163.8 0.7 2.4 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 EMC78792.1 - 1.1e-30 105.2 7.7 3.8e-30 103.4 5.3 2.0 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain COesterase PF00135.23 EMC78793.1 - 1.3e-184 614.8 0.0 1.5e-184 614.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC78793.1 - 2.8e-05 23.7 0.1 8.6e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Med12-LCEWAV PF12145.3 EMC78794.1 - 9.3e-205 680.6 2.0 1.3e-204 680.2 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain Med12-PQL PF12144.3 EMC78794.1 - 3.5e-80 268.2 33.6 3.5e-80 268.2 23.3 3.7 4 0 0 4 4 4 1 Eukaryotic Mediator 12 catenin-binding domain Med12 PF09497.5 EMC78794.1 - 6.1e-16 58.1 0.1 1.5e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 PA26 PF04636.8 EMC78795.1 - 2.2e-169 563.9 0.0 2.6e-169 563.7 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.15 EMC78795.1 - 0.0065 16.2 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PX PF00787.19 EMC78797.1 - 2.6e-26 91.6 0.1 3e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 PX domain WEMBL PF05701.6 EMC78798.1 - 0.0015 17.0 0.0 0.0017 16.9 0.0 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light HrpB7 PF09486.5 EMC78798.1 - 0.0025 17.7 0.4 0.0027 17.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Rootletin PF15035.1 EMC78798.1 - 0.011 15.7 0.3 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 EMC78798.1 - 0.026 14.4 2.0 0.032 14.1 1.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ufd2P_core PF10408.4 EMC78798.1 - 0.027 12.7 0.0 0.031 12.5 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core ALIX_LYPXL_bnd PF13949.1 EMC78798.1 - 0.037 12.9 0.3 0.048 12.6 0.2 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV FliJ PF02050.11 EMC78798.1 - 0.039 14.0 2.8 0.047 13.7 2.0 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein AA_permease_2 PF13520.1 EMC78799.1 - 4.9e-51 173.6 26.8 4.9e-51 173.6 18.6 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EMC78799.1 - 1.1e-35 122.9 28.0 1.1e-35 122.9 19.4 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 EMC78799.1 - 8.2e-23 80.0 7.8 8.2e-23 80.0 5.4 4.0 4 0 0 4 4 4 1 C-terminus of AA_permease RRM_1 PF00076.17 EMC78800.1 - 2.6e-18 65.4 0.0 3.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78800.1 - 9.3e-14 51.0 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78800.1 - 1.4e-13 50.5 0.0 1.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SPO22 PF08631.5 EMC78801.1 - 4e-60 203.2 10.7 3.4e-58 196.9 1.4 3.0 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EMC78801.1 - 8.6e-08 32.0 7.0 0.015 15.2 0.3 5.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC78801.1 - 1.3e-06 27.8 7.3 0.043 13.7 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC78801.1 - 5e-05 22.7 4.1 0.24 11.0 0.1 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMC78801.1 - 0.00014 21.3 9.3 0.00042 19.9 0.9 4.5 4 1 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 EMC78801.1 - 0.001 19.3 0.2 0.19 12.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC78801.1 - 0.0056 16.3 0.1 0.13 12.1 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC78801.1 - 0.07 13.8 0.8 45 5.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat GDPD PF03009.12 EMC78802.1 - 3.4e-22 79.1 0.0 1.1e-21 77.4 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Integrin_beta PF00362.13 EMC78802.1 - 6.7 5.4 9.0 0.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Integrin, beta chain 7tm_1 PF00001.16 EMC78803.1 - 5.3e-68 228.9 14.0 7.7e-68 228.4 9.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78803.1 - 7.9e-13 48.1 14.4 2.1e-12 46.7 10.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC78803.1 - 0.0013 17.8 13.2 0.0013 17.8 9.2 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Pox_P21 PF05313.7 EMC78803.1 - 0.033 13.4 0.6 0.033 13.4 0.4 2.7 3 0 0 3 3 3 0 Poxvirus P21 membrane protein RseC_MucC PF04246.7 EMC78803.1 - 0.048 13.2 0.3 0.048 13.2 0.2 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC fn3 PF00041.16 EMC78804.1 - 6.6e-05 22.9 0.2 9.9e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC78804.1 - 0.0006 19.9 0.5 0.0025 17.9 0.0 2.3 2 1 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding SusE PF14292.1 EMC78804.1 - 0.0058 16.4 0.0 0.0086 15.8 0.0 1.2 1 0 0 1 1 1 1 SusE outer membrane protein ERbeta_N PF12497.3 EMC78804.1 - 0.074 12.9 1.1 0.12 12.2 0.8 1.3 1 0 0 1 1 1 0 Estrogen receptor beta LRR_8 PF13855.1 EMC78805.1 - 1e-21 76.3 24.9 3.2e-09 36.4 1.8 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EMC78805.1 - 4.8e-16 57.9 13.2 3.1e-06 26.6 1.4 4.4 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC78805.1 - 5.6e-13 46.9 14.1 0.19 11.8 0.3 7.0 7 0 0 7 7 7 5 Leucine Rich Repeat CH PF00307.26 EMC78805.1 - 2.6e-10 40.2 0.1 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain LRR_7 PF13504.1 EMC78805.1 - 3.2e-07 29.4 11.9 2.6 8.6 0.2 6.5 6 0 0 6 6 6 2 Leucine rich repeat CAMSAP_CH PF11971.3 EMC78805.1 - 0.00092 18.8 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 EMC78805.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin LRR_6 PF13516.1 EMC78805.1 - 0.0049 16.7 8.6 20 5.6 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich repeat FYTT PF07078.6 EMC78806.1 - 0.2 10.9 5.2 0.25 10.6 3.6 1.1 1 0 0 1 1 1 0 Forty-two-three protein MPLKIP PF15502.1 EMC78806.1 - 1.6 9.4 13.2 1.9 9.1 9.1 1.1 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein CH PF00307.26 EMC78807.1 - 3.7e-82 271.4 1.2 8.1e-22 77.3 0.0 4.8 5 0 0 5 5 5 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EMC78807.1 - 2.5e-15 56.3 0.1 8.8e-15 54.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC78807.1 - 9.4e-12 43.3 3.2 1.3e-05 24.0 0.4 3.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EMC78807.1 - 1.1e-06 27.7 9.4 0.00042 19.5 0.0 4.6 4 1 1 5 5 5 2 EF hand CAMSAP_CH PF11971.3 EMC78807.1 - 1.2e-06 28.1 0.1 2.9e-05 23.6 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.1 EMC78807.1 - 3.1e-06 26.5 1.0 0.063 13.1 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EMC78807.1 - 0.0013 18.3 1.4 0.066 12.8 0.1 3.2 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC78807.1 - 0.008 16.2 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region LRR_8 PF13855.1 EMC78808.1 - 2.2e-42 142.6 49.8 8.9e-14 50.9 5.1 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EMC78808.1 - 4.6e-27 93.1 71.5 2.2e-07 30.3 5.8 6.8 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC78808.1 - 1e-20 70.5 41.1 0.0098 15.7 0.9 9.6 10 0 0 10 10 10 8 Leucine Rich Repeat LRR_5 PF13306.1 EMC78808.1 - 1.1e-13 50.9 1.4 1.9e-07 30.8 0.0 2.8 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC78808.1 - 7.8e-08 31.3 39.4 0.5 10.7 0.5 10.0 11 0 0 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 EMC78808.1 - 4.7e-05 23.0 41.6 1.5 9.1 1.7 9.6 8 1 2 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.1 EMC78808.1 - 0.00023 20.7 5.1 0.063 12.8 0.3 2.8 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.13 EMC78808.1 - 0.22 11.0 3.2 0.24 10.9 0.9 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain 7tm_1 PF00001.16 EMC78809.1 - 8.4e-66 221.7 18.1 1.1e-65 221.4 12.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78809.1 - 1.6e-09 37.3 15.5 2.1e-09 36.9 10.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC78809.1 - 4e-08 32.7 10.8 6.4e-08 32.0 7.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Flavi_NS2A PF01005.14 EMC78809.1 - 0.53 9.5 4.7 0.5 9.6 0.2 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2A DUF2668 PF10873.3 EMC78809.1 - 6.9 6.8 8.8 1.4 9.0 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) SNF PF00209.13 EMC78810.1 - 3.6e-197 655.9 41.6 4.4e-197 655.6 28.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.12 EMC78810.1 - 8.2 6.0 12.8 0.077 12.5 2.0 2.5 2 0 0 2 2 2 0 Caveolin DUF1075 PF06388.6 EMC78811.1 - 3e-39 133.9 0.4 3.6e-39 133.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) NB PF04159.8 EMC78811.1 - 0.012 15.2 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 NB glycoprotein DUF4389 PF14333.1 EMC78811.1 - 0.032 13.9 0.1 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Kelch_1 PF01344.20 EMC78812.1 - 3.3e-56 186.5 7.3 1.2e-11 44.0 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC78812.1 - 9.1e-37 123.7 2.6 9.4e-07 28.7 0.1 6.6 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 EMC78812.1 - 4.2e-27 93.9 0.0 8.9e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 EMC78812.1 - 5.4e-25 86.9 2.4 0.00011 22.2 0.0 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 EMC78812.1 - 6.6e-25 87.2 0.3 3.4e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 EMC78812.1 - 4e-24 83.3 5.3 2.9e-05 23.6 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EMC78812.1 - 7.8e-22 76.7 1.0 0.00073 19.2 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC78812.1 - 2.6e-12 46.3 13.1 0.0041 17.0 0.2 5.7 6 0 0 6 6 6 4 Kelch motif WD40 PF00400.27 EMC78813.1 - 1.2e-29 101.0 5.4 2e-07 30.5 0.1 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMC78813.1 - 0.0018 18.0 0.1 0.55 10.0 0.0 3.7 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 EMC78813.1 - 0.016 13.5 0.1 0.05 11.8 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Ded_cyto PF06920.8 EMC78814.1 - 8.1e-66 220.6 1.0 8.1e-66 220.6 0.7 3.4 4 0 0 4 4 4 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EMC78814.1 - 1.3e-56 191.1 0.2 6.9e-56 188.8 0.0 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 EMC78814.1 - 2e-32 110.9 2.1 2.2e-32 110.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PH PF00169.24 EMC78814.1 - 4.5e-10 39.6 1.4 1.3e-09 38.2 0.5 2.2 2 0 0 2 2 2 1 PH domain IL6Ra-bind PF09240.5 EMC78815.1 - 2.9e-19 69.0 0.1 7.5e-19 67.7 0.1 1.7 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 EMC78815.1 - 5.2e-08 32.8 0.1 1.8e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.12 EMC78815.1 - 0.00028 20.5 3.0 0.61 9.8 0.0 3.9 3 1 0 3 3 3 2 Tissue factor fn3 PF00041.16 EMC78815.1 - 0.00069 19.6 0.9 9 6.5 0.0 3.6 3 1 0 3 3 3 3 Fibronectin type III domain Pkinase PF00069.20 EMC78816.1 - 1.4e-71 240.7 0.0 2.3e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78816.1 - 5.4e-54 182.9 0.0 1e-53 182.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.6 EMC78816.1 - 4.2e-06 26.1 0.2 8.9e-06 25.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.1 EMC78816.1 - 0.0003 19.8 0.1 0.0022 16.9 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EMC78816.1 - 0.017 14.9 0.0 2.4 7.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4288 PF14119.1 EMC78816.1 - 0.069 13.2 1.0 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Kdo PF06293.9 EMC78816.1 - 0.092 11.7 0.1 0.57 9.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BLOC1_2 PF10046.4 EMC78816.1 - 0.13 12.4 2.8 0.76 9.9 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FERM_C PF09380.5 EMC78818.1 - 4.3e-27 94.1 0.3 8.2e-27 93.2 0.2 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 EMC78818.1 - 7.1e-15 55.2 0.2 1.3e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 FERM central domain FA PF08736.6 EMC78818.1 - 3.8e-13 48.9 1.7 3.8e-13 48.9 1.2 2.0 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.5 EMC78818.1 - 1.1e-12 47.7 3.2 1.6e-12 47.2 0.0 2.7 2 1 0 2 2 2 1 FERM N-terminal domain Ras PF00071.17 EMC78819.1 - 9.1e-56 187.7 0.3 3.8e-41 140.1 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EMC78819.1 - 3.2e-20 72.7 0.2 6.7e-20 71.7 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMC78819.1 - 2.2e-08 33.7 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMC78819.1 - 8.4e-08 31.6 0.0 1.2e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC78819.1 - 0.00042 20.2 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC78819.1 - 0.0024 17.1 0.1 0.012 14.9 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMC78819.1 - 0.075 12.2 0.0 0.58 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TPP_enzyme_M PF00205.17 EMC78819.1 - 0.08 12.6 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ArgK PF03308.11 EMC78819.1 - 0.11 11.2 0.2 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 ArgK protein zf-CCCH PF00642.19 EMC78821.1 - 1.3e-11 43.8 21.4 0.00052 19.6 0.3 4.7 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sulfotransfer_2 PF03567.9 EMC78822.1 - 1.1e-48 166.1 1.2 1.1e-48 166.1 0.8 1.6 2 0 0 2 2 2 1 Sulfotransferase family Phospholamban PF04272.9 EMC78822.1 - 0.094 12.1 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 Phospholamban Topoisom_I_N PF02919.10 EMC78822.1 - 0.15 11.3 5.2 0.28 10.4 3.6 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Sulfotransfer_2 PF03567.9 EMC78823.1 - 1.2e-18 67.7 0.2 1.3e-18 67.5 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family Glypican PF01153.14 EMC78825.1 - 1.3e-217 723.9 4.6 1.4e-217 723.7 3.2 1.0 1 0 0 1 1 1 1 Glypican Glypican PF01153.14 EMC78826.1 - 1.7e-165 551.8 2.0 1.9e-165 551.6 1.4 1.0 1 0 0 1 1 1 1 Glypican zf-HC5HC2H PF13771.1 EMC78828.1 - 5.7e-35 119.3 31.3 1.2e-18 66.9 6.3 3.5 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC78828.1 - 1.3e-12 47.6 27.9 2.2e-06 27.6 8.7 2.8 2 1 1 3 3 3 2 PHD-zinc-finger like domain zf-Apc11 PF12861.2 EMC78828.1 - 0.26 11.1 14.4 3 7.7 0.3 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pribosyltran PF00156.22 EMC78829.1 - 3.7e-14 52.5 0.1 5.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMC78829.1 - 0.026 13.7 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EMC78829.1 - 0.088 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 PRTase ComF-like PRTase_2 PF15609.1 EMC78829.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase DUF1582 PF07621.6 EMC78830.1 - 1.2 9.2 6.8 10 6.3 2.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1582) DUF1582 PF07621.6 EMC78831.1 - 0.4 10.7 5.9 9.4 6.4 3.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1582) FAM101 PF15068.1 EMC78831.1 - 1.1 8.6 6.0 0.15 11.5 0.4 2.1 2 1 0 2 2 2 0 FAM101 family DUF566 PF04484.7 EMC78831.1 - 4.6 6.6 12.4 2.9 7.3 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF566) Motile_Sperm PF00635.21 EMC78832.1 - 2.1e-17 62.7 0.2 3.3e-17 62.1 0.1 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain SPASM PF13186.1 EMC78832.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain MMgT PF10270.4 EMC78833.1 - 3.9e-15 56.1 0.0 6.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter LIM PF00412.17 EMC78834.1 - 3.3e-32 110.3 60.2 1.2e-11 44.5 3.9 5.3 4 1 1 5 5 5 5 LIM domain TNFR_c6 PF00020.13 EMC78834.1 - 0.13 12.3 0.4 0.13 12.3 0.3 7.5 6 3 1 7 7 7 0 TNFR/NGFR cysteine-rich region MAP7 PF05672.6 EMC78835.1 - 2.3e-12 46.6 13.9 2.3e-12 46.6 9.7 3.7 2 2 1 3 3 3 1 MAP7 (E-MAP-115) family DUF342 PF03961.8 EMC78835.1 - 8.7 4.6 16.0 16 3.7 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pentaxin PF00354.12 EMC78836.1 - 4.8e-12 45.7 0.5 1e-08 34.8 0.1 2.0 1 1 1 2 2 2 2 Pentaxin family Laminin_G_3 PF13385.1 EMC78836.1 - 2.7e-07 30.9 0.0 3.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily 7tm_2 PF00002.19 EMC78837.1 - 1.1e-50 172.0 23.9 1.6e-50 171.4 16.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 EMC78837.1 - 2.1e-14 53.3 3.3 3.9e-14 52.4 2.3 1.5 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain FA_desaturase PF00487.19 EMC78837.1 - 0.64 9.4 18.1 0.15 11.4 4.4 2.3 2 0 0 2 2 2 0 Fatty acid desaturase 7tm_1 PF00001.16 EMC78838.1 - 5.2e-59 199.4 14.3 8e-59 198.8 9.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78838.1 - 2e-11 43.5 14.4 3.3e-11 42.8 10.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC78838.1 - 1.1e-08 34.5 14.9 1.5e-08 34.1 10.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC78838.1 - 6e-05 22.2 12.9 9.2e-05 21.6 9.0 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.8 EMC78838.1 - 0.00036 19.5 3.7 0.00036 19.5 2.6 2.0 2 0 0 2 2 2 1 Mammalian taste receptor protein (TAS2R) DUF912 PF06024.7 EMC78838.1 - 2.8 8.0 5.2 2.7 8.1 1.3 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Vg_Tdu PF07545.9 EMC78839.1 - 7.6e-21 73.2 0.1 1.5e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family TNF PF00229.13 EMC78840.1 - 9.9e-31 105.9 0.4 1.7e-30 105.1 0.2 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 EMC78840.1 - 0.0078 16.2 1.0 0.031 14.2 0.3 2.3 2 1 0 2 2 2 1 C1q domain Feld-I_B PF09252.5 EMC78840.1 - 0.093 12.6 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Allergen Fel d I-B chain RhoGEF PF00621.15 EMC78841.1 - 4.2e-34 117.9 1.4 4.2e-34 117.9 1.0 2.9 2 1 1 3 3 3 1 RhoGEF domain SH3_9 PF14604.1 EMC78841.1 - 3.8e-17 61.5 0.2 9.1e-17 60.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC78841.1 - 1.6e-16 59.5 0.5 3.1e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC78841.1 - 7.2e-15 54.1 0.3 1.4e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EMC78841.1 - 1.2e-11 44.7 0.0 3.3e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 PH domain CH PF00307.26 EMC78841.1 - 1.3e-10 41.2 0.0 4.3e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC78841.1 - 0.00011 21.7 0.0 0.00046 19.7 0.0 2.1 1 0 0 1 1 1 1 CAMSAP CH domain MutS_III PF05192.13 EMC78841.1 - 0.095 12.4 5.0 1.2 8.8 0.2 3.0 2 1 0 2 2 2 0 MutS domain III Nsp1_C PF05064.8 EMC78841.1 - 0.41 10.3 13.2 0.034 13.7 1.2 3.7 4 1 0 4 4 4 0 Nsp1-like C-terminal region DUF972 PF06156.8 EMC78841.1 - 2 8.8 14.2 0.87 9.9 2.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 EMC78841.1 - 5.4 6.5 19.7 3.4 7.2 2.1 3.5 3 0 0 3 3 3 0 IncA protein DUF745 PF05335.8 EMC78841.1 - 6.2 6.3 6.5 2.2 7.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) RRM_1 PF00076.17 EMC78842.1 - 1e-23 82.7 0.1 1.5e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM1CTR PF08081.6 EMC78842.1 - 1e-22 79.5 18.9 1e-22 79.5 13.1 9.9 4 3 5 9 9 9 1 RBM1CTR (NUC064) family RRM_6 PF14259.1 EMC78842.1 - 2.9e-17 62.3 0.0 4.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78842.1 - 1e-11 44.4 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMP70 PF02990.11 EMC78843.1 - 3e-215 715.5 9.6 4.5e-215 715.0 6.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 zf-H2C2_2 PF13465.1 EMC78844.1 - 1.5e-23 81.8 28.2 2.3e-08 33.9 0.2 4.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC78844.1 - 3.9e-20 70.9 30.7 1.7e-06 28.0 2.0 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC78844.1 - 2.3e-15 55.6 25.5 9.8e-05 22.4 0.6 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC78844.1 - 2.7e-07 30.5 16.7 6.9e-05 22.8 0.1 4.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC78844.1 - 3.6e-06 26.9 8.3 0.00014 21.8 0.7 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC78844.1 - 0.00041 20.1 6.5 0.0013 18.5 0.2 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger IBR PF01485.16 EMC78844.1 - 1.2 9.0 6.6 12 5.8 3.5 2.5 1 1 0 1 1 1 0 IBR domain zf-BED PF02892.10 EMC78844.1 - 3.4 7.5 9.9 2.5 7.9 3.2 2.7 2 1 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 EMC78844.1 - 8.9 6.7 18.7 0.18 12.1 1.3 4.6 5 0 0 5 5 5 0 C2H2-type zinc-finger domain FGF PF00167.13 EMC78845.1 - 1.7e-44 150.5 0.3 2.7e-44 149.8 0.2 1.3 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 EMC78845.1 - 0.00083 19.4 0.1 0.0066 16.5 0.0 2.1 1 1 0 2 2 2 1 Fascin domain DUF1096 PF06493.6 EMC78845.1 - 2.5 8.0 8.1 31 4.5 5.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1096) Trypsin PF00089.21 EMC78846.1 - 1.3e-64 217.8 1.2 1.7e-64 217.3 0.8 1.2 1 0 0 1 1 1 1 Trypsin Gla PF00594.15 EMC78846.1 - 3.2e-18 65.1 5.1 5.2e-18 64.4 3.5 1.3 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.1 EMC78846.1 - 4.1e-13 49.2 21.8 1.1e-11 44.6 4.7 2.8 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 EMC78846.1 - 2.6e-08 33.6 16.3 2.4e-07 30.6 3.3 2.8 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.2 EMC78846.1 - 4.8e-06 26.0 13.5 9.8e-05 21.9 0.3 3.0 3 0 0 3 3 3 2 Complement Clr-like EGF-like Trypsin_2 PF13365.1 EMC78846.1 - 1.4e-05 25.0 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.2 EMC78846.1 - 0.024 14.7 7.7 0.39 10.8 2.5 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_CA PF07645.10 EMC78846.1 - 0.12 12.4 19.4 0.11 12.5 6.6 3.2 2 1 0 2 2 2 0 Calcium-binding EGF domain EGF_3 PF12947.2 EMC78846.1 - 0.25 11.3 22.7 2.1 8.3 4.9 2.7 2 0 0 2 2 2 0 EGF domain NUDE_C PF04880.8 EMC78847.1 - 1.4e-70 237.0 0.9 1.4e-70 237.0 0.6 2.8 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region HALZ PF02183.13 EMC78847.1 - 0.0087 15.7 2.9 0.0087 15.7 2.0 3.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper CCDC92 PF14916.1 EMC78847.1 - 0.45 10.1 8.8 0.59 9.7 0.0 3.5 2 1 1 3 3 3 0 Coiled-coil domain of unknown function ERM PF00769.14 EMC78847.1 - 0.62 9.5 31.8 0.046 13.2 8.7 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EMC78847.1 - 0.98 9.8 20.5 4.9 7.5 3.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Sigma54_AID PF00309.15 EMC78847.1 - 1.2 8.6 6.4 0.32 10.5 0.4 2.8 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) TPR_MLP1_2 PF07926.7 EMC78847.1 - 1.3 8.7 30.0 0.058 13.1 6.3 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EMC78847.1 - 1.3 8.8 31.3 0.27 11.0 16.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.4 EMC78847.1 - 1.4 8.9 15.1 0.062 13.2 2.8 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein GAS PF13851.1 EMC78847.1 - 1.6 7.8 30.0 1.7 7.7 9.9 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 EMC78847.1 - 2.4 8.1 32.1 2.1 8.3 8.4 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.7 EMC78847.1 - 3.9 7.2 9.3 13 5.6 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Striatin PF08232.7 EMC78847.1 - 4.3 7.6 22.6 8.2 6.7 5.8 3.7 2 1 1 3 3 3 0 Striatin family DUF2051 PF09738.4 EMC78847.1 - 4.5 6.4 30.5 2.8 7.1 10.5 3.1 2 1 2 4 4 4 0 Double stranded RNA binding protein (DUF2051) DUF904 PF06005.7 EMC78847.1 - 4.6 7.6 32.4 2.9 8.2 3.4 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 EMC78847.1 - 5.6 6.8 31.4 29 4.4 15.9 3.2 1 1 1 2 2 2 0 Tropomyosin like Pox_A_type_inc PF04508.7 EMC78847.1 - 7.1 6.7 0.0 7.1 6.7 0.0 5.9 6 1 0 6 6 6 0 Viral A-type inclusion protein repeat DMPK_coil PF08826.5 EMC78847.1 - 9.9 6.1 25.5 0.11 12.4 6.3 3.7 2 2 1 3 3 3 0 DMPK coiled coil domain like Myosin_head PF00063.16 EMC78848.1 - 2.1e-287 954.8 0.1 2.1e-287 954.8 0.1 4.5 3 1 1 5 5 5 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EMC78848.1 - 2.4e-204 680.6 330.9 2.3e-201 670.8 174.3 2.9 1 1 2 3 3 3 3 Myosin tail Myosin_N PF02736.14 EMC78848.1 - 8.6e-13 47.7 1.0 1.5e-12 46.9 0.1 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain ADIP PF11559.3 EMC78848.1 - 3.4e-05 23.7 20.3 3.4e-05 23.7 14.1 14.3 1 1 13 14 14 14 6 Afadin- and alpha -actinin-Binding IQ PF00612.22 EMC78848.1 - 0.0001 21.5 0.1 0.00036 19.9 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1664 PF07889.7 EMC78848.1 - 0.006 16.3 9.1 0.006 16.3 6.3 13.2 3 3 6 13 13 13 2 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EMC78848.1 - 0.31 10.1 74.0 0.15 11.2 0.7 9.1 3 2 5 9 9 9 0 Reovirus sigma C capsid protein Mab-21 PF03281.9 EMC78849.1 - 8.3e-14 51.3 0.1 8.8e-13 48.0 0.0 2.0 1 1 1 2 2 2 1 Mab-21 protein zf-TRM13_CCCH PF11722.3 EMC78849.1 - 0.092 12.1 1.5 0.4 10.1 0.2 2.3 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein Actin PF00022.14 EMC78850.1 - 1e-65 221.6 0.0 1.3e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Actin NYAP_N PF15439.1 EMC78851.1 - 1.4e-122 409.5 34.9 1.4e-122 409.5 24.2 3.3 2 1 0 2 2 2 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter NYAP_C PF15452.1 EMC78851.1 - 4.1e-13 49.0 7.6 8e-13 48.0 5.3 1.4 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Ded_cyto PF06920.8 EMC78852.1 - 1.7e-65 219.6 2.2 5.1e-65 218.0 1.5 1.9 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EMC78852.1 - 1.5e-54 184.4 1.5 2.4e-54 183.7 0.2 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 EMC78852.1 - 6.6e-31 106.0 0.8 1.7e-30 104.7 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.24 EMC78852.1 - 4.7e-11 42.8 2.3 1.7e-10 41.0 0.4 3.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EMC78852.1 - 0.0057 16.8 1.2 0.027 14.6 0.1 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Cullin PF00888.17 EMC78853.1 - 2e-202 673.9 10.4 2.4e-202 673.6 7.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMC78853.1 - 6e-30 102.8 2.0 2.5e-29 100.8 1.4 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2018 PF09442.5 EMC78853.1 - 0.052 14.1 1.1 1.3 9.6 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) FAM124 PF15067.1 EMC78854.1 - 6.4e-105 349.7 0.5 7.2e-105 349.6 0.4 1.0 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.15 EMC78855.1 - 6.7e-110 367.7 0.0 7.5e-110 367.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Granin PF01271.12 EMC78856.1 - 2.2e-148 495.5 39.2 2.5e-148 495.4 27.2 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) IF2_N PF04760.10 EMC78856.1 - 0.045 13.4 3.3 2.7 7.7 0.1 3.4 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region DUF4303 PF14136.1 EMC78856.1 - 0.25 10.9 4.0 0.42 10.2 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) ISK_Channel PF02060.10 EMC78857.1 - 9e-09 35.0 0.1 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DUF2207 PF09972.4 EMC78857.1 - 0.056 12.0 0.0 0.066 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AMP-binding PF00501.23 EMC78858.1 - 1.6e-93 313.4 0.1 2e-93 313.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC78858.1 - 6.4e-05 23.8 0.1 0.00019 22.3 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAGAT PF03982.8 EMC78859.1 - 1.1e-119 398.5 0.2 1.3e-119 398.2 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase B3_4 PF03483.12 EMC78860.1 - 7e-28 97.2 0.1 1.4e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EMC78860.1 - 6.7e-16 57.8 0.0 6.3e-15 54.7 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetase B5 domain PAP2 PF01569.16 EMC78861.1 - 5.5e-19 68.1 3.2 5.5e-19 68.1 2.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EMC78861.1 - 0.0024 17.4 0.9 0.0068 15.9 0.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily REC114-like PF15165.1 EMC78862.1 - 1.9e-82 276.6 0.2 2.2e-82 276.4 0.2 1.0 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like I-set PF07679.11 EMC78863.1 - 2.2e-29 101.1 1.6 1e-11 44.5 0.0 3.9 3 1 1 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78863.1 - 7.8e-23 80.4 2.0 4e-07 30.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC78863.1 - 9.1e-15 54.5 4.8 3.5e-09 36.6 0.0 3.9 4 1 0 4 4 4 2 Immunoglobulin domain Ig_3 PF13927.1 EMC78863.1 - 1.4e-13 51.0 7.5 1.4e-07 31.9 0.0 3.8 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC78863.1 - 2.4e-12 46.7 4.1 5.1e-05 23.1 0.0 4.2 2 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set PF05790.10 EMC78863.1 - 0.0019 18.1 0.0 0.23 11.4 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin C2-set domain Herpes_gE PF02480.11 EMC78863.1 - 0.027 12.7 0.1 1.9 6.6 0.0 2.4 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 EMC78863.1 - 0.33 10.8 3.6 50 3.9 0.0 3.7 3 2 1 4 4 4 0 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 EMC78864.1 - 5.1e-12 45.7 0.1 2.1e-05 24.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC78864.1 - 9.2e-09 35.2 0.0 4.7e-07 29.6 0.0 2.8 1 1 1 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 EMC78864.1 - 1e-08 34.9 0.0 0.0022 17.7 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC78864.1 - 3.8e-08 33.7 0.3 0.00012 22.5 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.10 EMC78864.1 - 7.5e-08 32.2 0.3 6.5e-07 29.2 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin C1-set domain ig PF00047.20 EMC78864.1 - 9.2e-08 32.1 0.4 0.071 13.2 0.1 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC78864.1 - 1.4e-07 31.3 0.1 8.4e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Marek_A PF02124.10 EMC78864.1 - 0.00023 20.7 0.3 0.00035 20.1 0.2 1.3 1 0 0 1 1 1 1 Marek's disease glycoprotein A DUF1191 PF06697.7 EMC78864.1 - 0.067 11.9 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF3995 PF13160.1 EMC78864.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Zona_pellucida PF00100.18 EMC78866.1 - 2.8e-49 167.9 0.0 3.3e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 EMC78867.1 - 5.7e-48 163.6 0.0 6.8e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3583 PF12126.3 EMC78869.1 - 1.1e-19 70.6 14.8 1.5e-19 70.2 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.19 EMC78869.1 - 7.3e-07 28.9 32.3 6.3e-05 22.7 9.9 4.0 4 2 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.1 EMC78869.1 - 3e-05 23.6 8.6 3e-05 23.6 6.0 3.6 3 0 0 3 3 3 1 zinc-RING finger domain NPBW PF15180.1 EMC78869.1 - 0.58 9.8 3.5 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Neuropeptides B and W Syntaxin-6_N PF09177.6 EMC78869.1 - 0.6 10.5 8.3 1.5 9.2 1.6 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Myb_DNA-bind_3 PF12776.2 EMC78869.1 - 0.72 10.5 4.9 1.5 9.4 1.1 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Spectrin PF00435.16 EMC78869.1 - 3.3 8.0 15.6 0.34 11.2 5.4 2.5 1 1 1 2 2 2 0 Spectrin repeat Band_7 PF01145.20 EMC78870.1 - 1.3e-17 64.3 0.0 2.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family SCP2 PF02036.12 EMC78870.1 - 2.1e-16 60.0 0.0 1.2e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EMC78870.1 - 0.028 14.3 0.0 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal DUF3583 PF12126.3 EMC78871.1 - 2.9e-22 79.1 5.8 2.9e-22 79.1 4.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3583) zf-B_box PF00643.19 EMC78871.1 - 0.00021 21.0 3.5 0.00021 21.0 2.4 4.2 4 1 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.1 EMC78871.1 - 0.00032 20.3 8.0 0.00032 20.3 5.6 4.5 4 0 0 4 4 4 2 zinc-RING finger domain Cep57_MT_bd PF06657.8 EMC78871.1 - 2.9 7.9 15.0 1.8 8.5 5.6 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 EMC78871.1 - 4 6.3 13.3 7.7 5.4 9.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 LRR_8 PF13855.1 EMC78872.1 - 4.3e-28 96.8 16.0 1.9e-11 43.5 0.2 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC78872.1 - 3.6e-13 48.8 13.1 8.3e-07 28.4 0.0 4.3 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.11 EMC78872.1 - 2.5e-12 46.4 0.0 9.8e-12 44.5 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78872.1 - 1e-09 38.3 0.6 2.8e-09 36.9 0.0 2.1 2 0 0 2 2 1 1 Immunoglobulin domain LRR_1 PF00560.28 EMC78872.1 - 1.2e-07 30.7 6.1 0.26 11.4 0.1 6.3 6 0 0 6 6 6 1 Leucine Rich Repeat Ig_3 PF13927.1 EMC78872.1 - 1.3e-07 32.0 0.0 7.1e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.1 EMC78872.1 - 7.7e-07 28.8 0.8 0.1 12.3 0.0 2.7 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) V-set PF07686.12 EMC78872.1 - 8.8e-06 25.5 0.0 3.7e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain LRR_9 PF14580.1 EMC78872.1 - 3.2e-05 23.5 1.1 0.0018 17.8 0.1 2.1 1 1 2 3 3 3 3 Leucine-rich repeat ig PF00047.20 EMC78872.1 - 4.9e-05 23.3 0.2 0.00021 21.3 0.2 2.2 1 1 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 EMC78872.1 - 0.0003 20.4 12.0 1.3 9.5 0.0 6.1 6 0 0 6 6 5 1 Leucine rich repeat LRR_6 PF13516.1 EMC78872.1 - 0.0036 17.2 14.6 2.8 8.2 0.2 5.6 5 1 0 5 5 5 1 Leucine Rich repeat fn3 PF00041.16 EMC78872.1 - 0.028 14.5 0.0 0.083 13.0 0.0 1.8 1 0 0 1 1 1 0 Fibronectin type III domain NosD PF05048.8 EMC78872.1 - 0.086 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) LRR_8 PF13855.1 EMC78873.1 - 1.2e-27 95.4 3.8 1.6e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EMC78873.1 - 3.6e-14 51.9 10.5 2.8e-06 26.8 0.0 4.3 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) I-set PF07679.11 EMC78873.1 - 6e-12 45.2 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78873.1 - 3.8e-09 36.5 0.4 8.1e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.28 EMC78873.1 - 3e-08 32.5 7.2 0.11 12.5 0.1 5.9 6 0 0 6 6 5 2 Leucine Rich Repeat Ig_3 PF13927.1 EMC78873.1 - 2.9e-06 27.6 1.3 1.3e-05 25.6 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.1 EMC78873.1 - 4.7e-06 26.2 0.2 0.00091 18.8 0.1 2.9 2 1 1 3 3 3 1 Leucine-rich repeat V-set PF07686.12 EMC78873.1 - 6.1e-06 26.1 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC78873.1 - 2.7e-05 24.1 0.1 0.00011 22.2 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 EMC78873.1 - 0.00013 21.6 13.4 0.36 11.2 0.0 6.6 7 0 0 7 7 7 2 Leucine rich repeat LRR_5 PF13306.1 EMC78873.1 - 0.00062 19.4 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC78873.1 - 0.035 14.1 15.8 0.52 10.5 0.2 6.1 6 1 1 7 7 6 0 Leucine Rich repeat RBP_receptor PF14752.1 EMC78874.1 - 2.3e-225 749.6 17.6 2.8e-225 749.3 12.2 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor BpuJI_N PF11564.3 EMC78875.1 - 0.17 10.7 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal p450 PF00067.17 EMC78876.1 - 3.4e-35 121.4 0.0 1.9e-28 99.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Sema PF01403.14 EMC78877.1 - 8.9e-70 235.3 0.0 1.2e-69 234.9 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 EMC78877.1 - 1.4e-06 28.3 4.0 1.4e-06 28.3 2.8 2.2 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.1 EMC78877.1 - 0.00012 22.1 2.5 0.00026 21.0 1.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain DUF4589 PF15252.1 EMC78878.1 - 0.69 9.6 6.6 0.62 9.8 3.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4589) PID PF00640.18 EMC78881.1 - 1.4e-34 119.0 0.3 2.1e-34 118.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 EMC78881.1 - 1.3e-12 47.7 0.2 2.3e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 EMC78881.1 - 1.1e-05 25.1 0.1 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DivIC PF04977.10 EMC78881.1 - 0.0012 18.2 4.6 0.0022 17.4 3.2 1.3 1 0 0 1 1 1 1 Septum formation initiator DUF3373 PF11853.3 EMC78881.1 - 0.0014 17.3 0.2 0.0018 16.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) bZIP_2 PF07716.10 EMC78881.1 - 0.0014 18.4 4.8 0.003 17.3 3.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Ax_dynein_light PF10211.4 EMC78881.1 - 0.0037 17.1 0.3 0.0063 16.3 0.2 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain TSC22 PF01166.13 EMC78881.1 - 0.0037 17.1 1.2 0.0098 15.8 0.8 1.7 1 0 0 1 1 1 1 TSC-22/dip/bun family Herpes_BLRF2 PF05812.7 EMC78881.1 - 0.0076 16.0 1.1 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein ATG16 PF08614.6 EMC78881.1 - 0.0077 16.0 0.8 0.012 15.4 0.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 EMC78881.1 - 0.0094 15.8 1.7 0.016 15.1 1.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor Spc24 PF08286.6 EMC78881.1 - 0.01 15.5 0.3 0.021 14.5 0.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Leu_zip PF15294.1 EMC78881.1 - 0.011 14.9 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Leucine zipper DUF4200 PF13863.1 EMC78881.1 - 0.016 15.1 1.1 0.022 14.6 0.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 EMC78881.1 - 0.02 15.2 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Herpes_UL6 PF01763.11 EMC78881.1 - 0.026 12.6 0.0 0.041 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Striatin PF08232.7 EMC78881.1 - 0.027 14.7 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Striatin family ORF6C PF10552.4 EMC78881.1 - 0.03 14.0 0.6 0.073 12.8 0.4 1.6 1 0 0 1 1 1 0 ORF6C domain IncA PF04156.9 EMC78881.1 - 0.032 13.8 0.4 0.045 13.3 0.3 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EMC78881.1 - 0.035 13.9 5.0 0.086 12.6 3.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nnf1 PF03980.9 EMC78881.1 - 0.043 13.8 3.0 0.043 13.8 2.1 1.6 2 0 0 2 2 1 0 Nnf1 Med4 PF10018.4 EMC78881.1 - 0.045 13.1 0.2 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin_2 PF01920.15 EMC78881.1 - 0.063 13.0 2.8 0.13 12.0 1.9 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF904 PF06005.7 EMC78881.1 - 0.067 13.4 3.6 0.14 12.4 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Pox_A_type_inc PF04508.7 EMC78881.1 - 0.36 10.7 2.3 0.74 9.7 0.3 2.3 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF4315 PF14193.1 EMC78881.1 - 1.6 8.7 5.4 0.54 10.2 1.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4315) M PF02370.11 EMC78881.1 - 9.2 7.0 6.7 6.9 7.4 2.5 2.5 2 1 1 3 3 2 0 M protein repeat COLFI PF01410.13 EMC78882.1 - 1.7e-26 92.9 0.0 1.9e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Collagen PF01391.13 EMC78883.1 - 5.2e-166 538.3 709.5 4.8e-09 35.6 23.2 21.9 2 2 17 19 19 19 18 Collagen triple helix repeat (20 copies) COLFI PF01410.13 EMC78883.1 - 3.1e-92 307.8 0.1 3.8e-92 307.5 0.1 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.13 EMC78883.1 - 9.9e-13 47.9 16.3 2e-12 47.0 11.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type C domain Amnionless PF14828.1 EMC78883.1 - 0.16 10.4 14.1 0.22 9.9 9.8 1.1 1 0 0 1 1 1 0 Amnionless Fibrinogen_C PF00147.13 EMC78883.1 - 0.45 10.0 0.2 0.64 9.5 0.1 1.1 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Ald_Xan_dh_C2 PF02738.13 EMC78884.1 - 5.3e-206 685.1 0.0 7.3e-206 684.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EMC78884.1 - 2.4e-54 183.3 0.0 4.1e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EMC78884.1 - 3.9e-37 126.7 1.3 6.7e-37 125.9 0.9 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EMC78884.1 - 1.6e-32 111.4 0.0 5.3e-32 109.8 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EMC78884.1 - 6.6e-28 96.4 0.1 1.9e-27 94.9 0.1 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EMC78884.1 - 0.027 14.2 8.1 0.017 14.8 2.6 2.7 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Sulfotransfer_2 PF03567.9 EMC78885.1 - 9.8e-09 35.2 0.0 5.2e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family DUF1654 PF07867.6 EMC78885.1 - 0.011 15.0 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) DUF521 PF04412.8 EMC78885.1 - 0.2 10.1 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Dynamin_N PF00350.18 EMC78886.1 - 2.8e-19 69.5 0.0 1.2e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 EMC78886.1 - 3e-19 68.6 0.2 1.6e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 EMC78886.1 - 1.1e-09 38.2 0.0 4.8e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMC78886.1 - 0.00018 21.9 0.0 0.0097 16.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMC78886.1 - 0.00083 18.8 0.2 0.034 13.5 0.3 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.27 EMC78886.1 - 0.00099 18.2 0.6 0.0033 16.6 0.1 2.2 2 0 0 2 2 1 1 EF hand FeoB_N PF02421.13 EMC78886.1 - 0.009 15.3 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 EMC78886.1 - 0.011 14.7 0.0 0.067 12.2 0.0 2.2 3 0 0 3 3 3 0 AIG1 family AAA_28 PF13521.1 EMC78886.1 - 0.012 15.5 0.0 0.091 12.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.7 EMC78886.1 - 0.013 14.6 0.1 0.23 10.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region UPF0278 PF08745.6 EMC78886.1 - 0.022 14.0 0.2 0.046 12.9 0.0 1.5 2 0 0 2 2 2 0 UPF0278 family AAA_22 PF13401.1 EMC78886.1 - 0.03 14.4 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EMC78886.1 - 0.036 13.4 0.0 6 6.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_7 PF13499.1 EMC78886.1 - 0.067 13.3 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 1 0 EF-hand domain pair MobB PF03205.9 EMC78886.1 - 0.084 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Spc7 PF08317.6 EMC78886.1 - 0.094 11.3 3.7 0.034 12.8 0.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_16 PF13191.1 EMC78886.1 - 0.12 12.3 0.2 5.5 6.9 0.0 3.1 2 1 0 3 3 3 0 AAA ATPase domain UPF0079 PF02367.12 EMC78886.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 EF-hand_8 PF13833.1 EMC78886.1 - 0.37 10.4 2.2 0.49 10.0 0.3 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 EMC78886.1 - 2.7 7.4 5.0 0.57 9.6 0.5 2.2 2 0 0 2 2 2 0 EF hand Glycos_transf_2 PF00535.21 EMC78887.1 - 9.2e-20 70.9 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC78887.1 - 2.9e-17 62.8 2.4 5.2e-17 62.0 1.7 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EMC78887.1 - 2e-07 30.3 0.0 4.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 EMC78887.1 - 2.5e-06 27.4 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMC78887.1 - 0.00078 18.6 0.0 0.0044 16.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 EMC78887.1 - 0.021 13.9 0.4 0.091 11.8 0.0 2.1 2 1 0 2 2 2 0 Glycosyltransferase (GlcNAc) Peptidase_C2 PF00648.16 EMC78888.1 - 1.7e-105 352.2 0.1 2e-105 352.0 0.1 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C47 PF05543.8 EMC78888.1 - 0.0002 20.8 0.3 0.00032 20.1 0.2 1.2 1 0 0 1 1 1 1 Staphopain peptidase C47 HSF_DNA-bind PF00447.12 EMC78889.1 - 5.4e-07 29.7 0.0 6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Acyltransferase PF01553.16 EMC78890.1 - 1.6e-21 76.0 0.0 2.6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Lbh PF15317.1 EMC78891.1 - 8e-37 125.3 2.8 1e-36 125.0 1.9 1.1 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Yippee-Mis18 PF03226.9 EMC78892.1 - 7.1e-18 64.4 0.2 8e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EMC78892.1 - 0.0046 16.9 0.1 0.072 13.1 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.10 EMC78892.1 - 0.0068 16.0 0.7 0.034 13.8 0.3 2.0 1 1 1 2 2 2 1 Recombination endonuclease VII SelR PF01641.13 EMC78892.1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 SelR domain RIG-I_C-RD PF11648.3 EMC78892.1 - 0.016 15.0 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I HECT_2 PF09814.4 EMC78892.1 - 0.042 12.5 0.8 0.09 11.4 0.0 1.7 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Mut7-C PF01927.11 EMC78892.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain Sgf11 PF08209.6 EMC78892.1 - 0.31 10.3 3.0 6 6.2 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Rpr2 PF04032.11 EMC78892.1 - 0.68 9.8 2.8 4.3 7.2 0.2 2.2 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ank_5 PF13857.1 EMC78893.1 - 2e-09 37.3 0.2 3.4e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC78893.1 - 2.3e-09 37.4 0.0 1.5e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC78893.1 - 3.6e-09 35.9 1.8 1.1e-06 28.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EMC78893.1 - 2.2e-06 27.3 0.1 0.0026 17.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC78893.1 - 2.2e-06 28.0 0.1 0.37 11.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC78893.1 - 0.016 15.0 0.6 0.049 13.4 0.4 1.8 1 0 0 1 1 1 0 SOCS box Steroid_dh PF02544.11 EMC78894.1 - 1.7e-58 196.6 1.0 1.9e-58 196.5 0.7 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EMC78894.1 - 3e-06 26.6 0.1 3.3e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ferric_reduct PF01794.14 EMC78894.1 - 0.052 13.6 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase like transmembrane component PEMT PF04191.8 EMC78894.1 - 0.16 12.1 1.6 0.2 11.7 0.3 1.9 2 1 0 2 2 2 0 Phospholipid methyltransferase Nol1_Nop2_Fmu PF01189.12 EMC78895.1 - 2.9e-36 125.3 0.1 8.7e-20 71.2 0.0 3.3 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 EMC78895.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase UQ_con PF00179.21 EMC78896.1 - 6.6e-09 35.3 0.0 7.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC78896.1 - 4.4e-05 23.2 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Med10 PF09748.4 EMC78897.1 - 1.4e-29 102.4 2.1 5.4e-29 100.6 1.5 1.7 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Synaptonemal_3 PF15191.1 EMC78897.1 - 0.17 11.6 1.1 20 5.0 0.1 2.8 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 DUF4483 PF14825.1 EMC78898.1 - 0.0037 16.9 0.3 0.0061 16.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) PNP_UDP_1 PF01048.15 EMC78899.1 - 4.9e-28 97.6 0.0 5.7e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily VWC PF00093.13 EMC78903.1 - 1.6e-10 40.8 55.3 2.8e-09 36.9 11.4 4.0 4 0 0 4 4 4 3 von Willebrand factor type C domain Pacifastin_I PF05375.8 EMC78903.1 - 8.4e-05 21.9 4.1 8.4e-05 21.9 2.9 4.0 4 0 0 4 4 4 2 Pacifastin inhibitor (LCMII) B12D PF06522.6 EMC78905.1 - 5.8e-18 64.3 0.0 6.6e-18 64.1 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PSI_8 PF00796.13 EMC78905.1 - 0.12 11.9 0.5 0.17 11.5 0.3 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Cation_efflux PF01545.16 EMC78906.1 - 4.2e-49 167.1 15.5 4e-29 101.6 8.4 2.0 2 0 0 2 2 2 2 Cation efflux family DUF3681 PF12442.3 EMC78906.1 - 0.025 14.7 0.2 0.083 13.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) DUF1282 PF06930.7 EMC78906.1 - 0.041 13.5 6.8 0.4 10.3 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) DUF3112 PF11309.3 EMC78906.1 - 4.1 7.1 8.8 17 5.1 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Snapin_Pallidin PF14712.1 EMC78907.1 - 7.1e-22 77.5 3.4 8.8e-22 77.2 2.4 1.0 1 0 0 1 1 1 1 Snapin/Pallidin Tup_N PF08581.5 EMC78907.1 - 0.14 12.3 3.1 1.6 9.0 0.3 2.1 2 0 0 2 2 2 0 Tup N-terminal Pyr_redox_2 PF07992.9 EMC78908.1 - 3.8e-09 36.7 0.0 1.9e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC78908.1 - 0.00054 20.0 0.2 3.3 7.7 0.2 3.2 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMC78908.1 - 0.025 14.3 0.0 0.73 9.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AAA_18 PF13238.1 EMC78909.1 - 3.7e-08 33.7 0.1 1.1e-07 32.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain Peptidase_A22B PF04258.8 EMC78910.1 - 5.7e-85 285.3 20.6 1e-84 284.5 14.3 1.3 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 EMC78910.1 - 3.4e-16 58.7 0.0 6e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 PA domain Presenilin PF01080.12 EMC78910.1 - 0.001 17.9 3.3 0.001 17.9 2.3 2.1 2 0 0 2 2 2 1 Presenilin Tic20 PF09685.5 EMC78910.1 - 0.058 13.3 0.2 0.058 13.3 0.1 4.1 4 1 0 4 4 4 0 Tic20-like protein V_ATPase_I PF01496.14 EMC78910.1 - 0.07 10.9 1.3 0.17 9.7 0.9 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2077 PF09850.4 EMC78910.1 - 0.22 10.9 1.7 0.41 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) MMPL PF03176.10 EMC78910.1 - 0.25 10.0 4.6 2.8 6.5 0.0 2.4 2 0 0 2 2 2 0 MMPL family Alpha_kinase PF02816.13 EMC78911.1 - 4.3e-38 130.8 0.0 1.1e-37 129.5 0.0 1.7 1 0 0 1 1 1 1 Alpha-kinase family Ion_trans PF00520.26 EMC78911.1 - 2.1e-07 30.4 18.9 3.9e-07 29.5 13.1 1.5 1 0 0 1 1 1 1 Ion transport protein UCH PF00443.24 EMC78912.1 - 3.8e-87 291.8 6.0 3.8e-87 291.8 4.2 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 EMC78912.1 - 3.3e-31 107.5 6.5 3.3e-31 107.5 4.5 2.5 2 0 0 2 2 2 1 USP8 dimerisation domain UCH_1 PF13423.1 EMC78912.1 - 6.5e-28 98.0 3.2 6.5e-28 98.0 2.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EMC78912.1 - 4.1e-10 40.0 0.0 4e-09 36.8 0.0 2.8 2 0 0 2 2 2 1 Rhodanese-like domain SAPS PF04499.10 EMC78912.1 - 0.00063 18.5 10.6 0.0011 17.7 3.7 2.4 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Metallothio_Pro PF02069.11 EMC78912.1 - 0.089 12.6 0.6 0.36 10.6 0.4 1.9 2 0 0 2 2 2 0 Prokaryotic metallothionein Ank_2 PF12796.2 EMC78913.1 - 2.9e-55 184.5 12.1 2.2e-22 79.1 0.5 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC78913.1 - 1.5e-37 125.5 0.8 1e-11 44.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EMC78913.1 - 5.9e-28 94.1 0.5 3.4e-08 32.9 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EMC78913.1 - 1.4e-27 95.0 1.1 3.6e-09 36.5 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC78913.1 - 3.4e-24 84.7 0.3 1.9e-10 40.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pyridoxal_deC PF00282.14 EMC78914.1 - 1.3e-164 547.1 0.0 1.6e-164 546.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMC78914.1 - 6.8e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMC78914.1 - 0.019 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Amidinotransf PF02274.12 EMC78915.1 - 3.7e-07 29.5 0.0 0.0037 16.4 0.0 2.2 2 0 0 2 2 2 2 Amidinotransferase PDEase_I PF00233.14 EMC78916.1 - 1.8e-64 217.7 1.0 3.3e-64 216.8 0.7 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 EMC78916.1 - 6.1e-15 55.1 0.0 1.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EMC78916.1 - 1.4e-13 51.0 0.0 4.9e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EMC78916.1 - 1.3e-12 47.4 0.3 5.6e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EMC78916.1 - 5.7e-06 26.3 0.0 2.1e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EMC78916.1 - 0.00022 21.2 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EMC78916.1 - 0.00024 20.8 0.0 0.00081 19.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain WH1 PF00568.18 EMC78917.1 - 2.8e-36 123.6 0.4 6.5e-36 122.4 0.3 1.6 1 0 0 1 1 1 1 WH1 domain CALCOCO1 PF07888.6 EMC78917.1 - 3.3e-05 22.3 27.4 3.3e-05 22.3 19.0 1.6 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.1 EMC78917.1 - 4.1e-05 22.8 40.5 0.00041 19.5 9.2 3.5 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding DMPK_coil PF08826.5 EMC78917.1 - 8.2e-05 22.4 3.7 8.2e-05 22.4 2.6 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like Macoilin PF09726.4 EMC78917.1 - 9.1e-05 20.9 23.6 0.00012 20.4 16.4 1.2 1 0 0 1 1 1 1 Transmembrane protein IncA PF04156.9 EMC78917.1 - 0.0021 17.6 21.5 0.0021 17.6 14.9 3.0 1 1 1 3 3 3 2 IncA protein DUF4201 PF13870.1 EMC78917.1 - 0.0029 17.0 6.7 0.0029 17.0 4.7 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4201) COG6 PF06419.6 EMC78917.1 - 0.0057 14.8 4.4 0.0057 14.8 3.1 2.6 2 1 1 3 3 2 1 Conserved oligomeric complex COG6 Reo_sigmaC PF04582.7 EMC78917.1 - 0.0072 15.5 12.1 0.0091 15.2 0.9 2.5 2 1 1 3 3 2 2 Reovirus sigma C capsid protein MscS_porin PF12795.2 EMC78917.1 - 0.009 15.3 19.6 0.009 15.3 13.6 2.3 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain bZIP_1 PF00170.16 EMC78917.1 - 0.009 15.9 3.4 0.009 15.9 2.3 5.7 2 1 4 6 6 5 1 bZIP transcription factor FUSC PF04632.7 EMC78917.1 - 0.065 11.6 4.1 0.1 11.0 2.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.7 EMC78917.1 - 0.073 12.8 22.5 0.056 13.1 4.4 3.0 2 1 1 3 3 3 0 Laminin Domain II Mod_r PF07200.8 EMC78917.1 - 0.12 12.2 34.8 1.6 8.6 5.2 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3584 PF12128.3 EMC78917.1 - 0.21 8.9 36.0 0.0045 14.4 19.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 EMC78917.1 - 0.22 9.2 41.6 0.44 8.2 28.7 1.4 1 1 0 1 1 1 0 Myosin tail TMEM192 PF14802.1 EMC78917.1 - 0.23 10.2 6.0 0.36 9.6 1.5 2.6 1 1 1 2 2 2 0 TMEM192 family DUF3461 PF11944.3 EMC78917.1 - 0.32 10.8 17.7 0.49 10.2 4.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) BLOC1_2 PF10046.4 EMC78917.1 - 0.33 11.0 24.0 0.051 13.7 1.3 3.5 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MAD PF05557.8 EMC78917.1 - 0.36 8.8 39.6 0.034 12.2 22.9 2.1 1 1 0 2 2 2 0 Mitotic checkpoint protein Hemerythrin PF01814.18 EMC78917.1 - 0.39 10.8 9.1 0.15 12.1 3.7 2.2 3 0 0 3 3 2 0 Hemerythrin HHE cation binding domain WEMBL PF05701.6 EMC78917.1 - 0.43 8.9 38.7 0.62 8.4 24.1 2.4 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 EMC78917.1 - 0.45 10.3 45.8 0.017 14.9 24.7 3.0 2 1 0 2 2 2 0 Tropomyosin like DUF948 PF06103.6 EMC78917.1 - 0.54 10.1 13.7 0.78 9.6 1.3 3.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.6 EMC78917.1 - 0.54 8.7 38.4 3.4 6.0 18.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) NPV_P10 PF05531.7 EMC78917.1 - 0.6 10.3 11.3 8 6.7 0.5 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 EMC78917.1 - 1 8.7 35.3 1.8 7.9 12.9 2.9 1 1 1 2 2 2 0 Intermediate filament protein Lebercilin PF15619.1 EMC78917.1 - 1.1 8.6 41.2 0.16 11.3 12.0 3.2 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.7 EMC78917.1 - 1.1 7.3 32.4 0.065 11.4 18.3 1.9 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 EMC78917.1 - 1.2 7.5 33.0 0.067 11.6 18.1 1.9 1 1 0 1 1 1 0 AAA domain DUF4600 PF15372.1 EMC78917.1 - 1.3 9.2 30.7 0.072 13.3 7.4 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4600) Cluap1 PF10234.4 EMC78917.1 - 1.3 8.1 33.6 3.6 6.7 12.6 2.4 1 1 1 2 2 2 0 Clusterin-associated protein-1 TMF_TATA_bd PF12325.3 EMC78917.1 - 1.3 8.7 39.5 3.7 7.2 13.7 3.7 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.1 EMC78917.1 - 1.4 8.9 46.6 0.54 10.2 12.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 EMC78917.1 - 1.4 9.2 35.9 0.94 9.8 7.2 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF972) DUF2353 PF09789.4 EMC78917.1 - 1.4 8.0 27.5 12 5.0 18.1 2.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.4 EMC78917.1 - 1.6 8.5 49.1 0.62 9.9 1.9 3.4 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Leu_zip PF15294.1 EMC78917.1 - 1.8 7.6 39.4 0.61 9.1 19.8 2.4 1 1 1 2 2 2 0 Leucine zipper Fez1 PF06818.10 EMC78917.1 - 2.8 7.8 34.8 2.1 8.2 18.0 2.1 1 1 1 2 2 2 0 Fez1 ING PF12998.2 EMC78917.1 - 2.9 8.1 26.1 1.7 8.9 4.7 3.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DASH_Dad2 PF08654.5 EMC78917.1 - 3.1 7.8 19.1 0.48 10.4 3.2 3.8 2 1 2 4 4 3 0 DASH complex subunit Dad2 TPR_MLP1_2 PF07926.7 EMC78917.1 - 3.9 7.2 47.2 0.21 11.3 3.9 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Dor1 PF04124.7 EMC78917.1 - 4 5.8 24.3 0.17 10.2 12.6 1.9 2 1 0 2 2 1 0 Dor1-like family Baculo_PEP_C PF04513.7 EMC78917.1 - 4.1 7.2 13.3 5.2 6.8 0.6 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 EMC78917.1 - 4.4 4.6 16.8 0.87 7.0 9.1 1.6 2 0 0 2 2 2 0 Prominin ADIP PF11559.3 EMC78917.1 - 5.5 6.8 47.0 4 7.3 10.3 4.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 EMC78917.1 - 5.9 6.0 27.2 10 5.3 8.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Sec34 PF04136.10 EMC78917.1 - 6.3 6.4 17.1 12 5.5 2.5 2.4 1 1 1 2 2 2 0 Sec34-like family Seryl_tRNA_N PF02403.17 EMC78917.1 - 7.3 6.6 36.4 0.75 9.8 8.7 4.0 2 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Tnp_P_element PF12017.3 EMC78917.1 - 7.7 5.6 16.1 1.6 7.8 2.7 2.7 1 1 1 3 3 3 0 Transposase protein MerR-DNA-bind PF09278.6 EMC78917.1 - 7.9 6.9 20.2 0.78 10.1 1.1 4.6 2 2 2 4 4 4 0 MerR, DNA binding ATG16 PF08614.6 EMC78917.1 - 8.2 6.2 44.2 12 5.6 8.6 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) KLRAQ PF10205.4 EMC78917.1 - 8.7 6.4 32.9 8.3 6.5 6.6 4.4 2 1 2 4 4 4 0 Predicted coiled-coil domain-containing protein RAM PF15320.1 EMC78918.1 - 1.6e-22 79.5 1.5 1.7e-22 79.4 1.1 1.0 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein DUF167 PF02594.11 EMC78919.1 - 6.8e-19 67.5 0.1 8.3e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 PHR PF08005.7 EMC78920.1 - 2.1e-49 167.5 0.4 3.2e-49 167.0 0.3 1.3 1 0 0 1 1 1 1 PHR domain BACK PF07707.10 EMC78920.1 - 1.9e-09 37.2 0.2 3.5e-08 33.1 0.0 2.7 1 1 1 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 EMC78920.1 - 5.8e-07 29.4 0.3 1.5e-05 24.9 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain DUF2781 PF10914.3 EMC78921.1 - 1.1e-34 119.3 4.2 1.1e-34 119.3 2.9 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2781) ApoM PF11032.3 EMC78921.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein M (ApoM) HSP20 PF00011.16 EMC78923.1 - 2.8e-08 33.5 0.1 3.6e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.6 EMC78923.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 YabP family SRRM_C PF15230.1 EMC78924.1 - 9.4e-26 89.6 30.5 9.4e-26 89.6 21.1 10.5 4 3 5 9 9 9 1 Serine/arginine repetitive matrix protein C-terminus I-set PF07679.11 EMC78925.1 - 7.6e-22 76.9 0.0 1.8e-11 43.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78925.1 - 5.7e-19 68.0 2.5 3.3e-08 33.5 0.1 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC78925.1 - 9.2e-16 57.7 0.1 7e-09 35.5 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.20 EMC78925.1 - 7.1e-13 48.4 3.2 3.1e-06 27.1 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC78925.1 - 6e-12 45.8 9.7 0.008 16.6 0.7 4.2 3 1 1 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.7 EMC78925.1 - 4.9e-08 32.7 3.5 0.0013 18.5 0.1 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain YPEB PF14620.1 EMC78926.1 - 0.0052 15.8 1.7 0.0059 15.6 1.2 1.0 1 0 0 1 1 1 1 YpeB sporulation CALCOCO1 PF07888.6 EMC78926.1 - 0.054 11.7 2.3 0.062 11.5 1.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.4 EMC78926.1 - 0.12 11.2 3.6 0.16 10.8 2.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2664 PF10867.3 EMC78926.1 - 0.31 11.6 3.9 0.45 11.1 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) OEP PF02321.13 EMC78926.1 - 0.69 9.4 10.4 0.87 9.1 7.2 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DEAD PF00270.24 EMC78927.1 - 2.9e-47 160.3 0.2 8.2e-47 158.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC78927.1 - 8e-21 73.6 0.0 1.6e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EMC78927.1 - 7.3e-20 70.5 7.2 1.8e-19 69.3 5.0 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 EMC78927.1 - 2.8e-07 30.5 1.4 1.7e-06 27.9 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit PAPS_reduct PF01507.14 EMC78927.1 - 0.0058 16.4 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ion_trans PF00520.26 EMC78928.1 - 2.4e-48 164.0 52.6 3.9e-29 101.3 16.4 2.3 2 0 0 2 2 2 2 Ion transport protein OppC_N PF12911.2 EMC78928.1 - 0.00099 18.4 7.7 0.85 9.0 1.2 4.2 3 0 0 3 3 3 3 N-terminal TM domain of oligopeptide transport permease C PALP PF00291.20 EMC78929.1 - 7.2e-49 166.6 0.2 5.4e-47 160.5 0.2 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HEAT_2 PF13646.1 EMC78929.1 - 0.074 13.3 1.3 7.8 6.8 0.2 2.9 3 0 0 3 3 3 0 HEAT repeats RRM_1 PF00076.17 EMC78930.1 - 1.2e-89 293.9 5.0 3.3e-19 68.2 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC78930.1 - 3.2e-83 273.6 1.8 7.8e-18 64.2 0.0 6.3 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78930.1 - 1.6e-42 143.1 0.9 2.3e-09 36.9 0.0 6.3 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC78930.1 - 1.4e-05 24.9 12.4 0.48 10.2 0.1 7.3 6 2 2 8 8 8 2 RNA binding motif Nup35_RRM_2 PF14605.1 EMC78930.1 - 0.00033 20.3 0.2 4.5 7.1 0.0 4.7 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EMC78930.1 - 0.0023 17.6 0.0 1.5 8.6 0.0 4.7 4 1 0 4 4 4 1 Limkain b1 DnaJ-X PF14308.1 EMC78930.1 - 0.0092 15.2 0.5 0.0092 15.2 0.4 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing T-box PF00907.17 EMC78932.1 - 7.2e-57 191.8 0.0 1.6e-50 171.1 0.0 2.1 2 0 0 2 2 2 2 T-box Sulfotransfer_2 PF03567.9 EMC78933.1 - 3.2e-31 108.9 0.1 4.2e-31 108.5 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EMC78933.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain Pkinase PF00069.20 EMC78934.1 - 4.2e-66 222.7 0.0 7e-66 222.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78934.1 - 1.4e-40 139.0 0.0 2.1e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EMC78934.1 - 1.8e-19 69.2 6.5 1.3e-14 53.6 0.6 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 EMC78934.1 - 6e-11 42.6 0.6 1.6e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC78934.1 - 3.5e-06 26.1 0.0 1.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Uds1 PF15456.1 EMC78934.1 - 0.076 13.0 1.0 0.2 11.6 0.2 1.9 1 1 1 2 2 2 0 Up-regulated During Septation TFIIB PF00382.14 EMC78935.1 - 1.4e-52 175.4 1.8 6.6e-26 89.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMC78935.1 - 1.5e-14 53.0 0.3 2.3e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EMC78935.1 - 1.3e-08 34.4 0.0 5e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC78935.1 - 0.00034 20.5 0.3 0.061 13.2 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 EMC78935.1 - 0.0079 15.4 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 DUF3733 PF12534.3 EMC78936.1 - 3.7e-43 144.6 12.5 3.9e-25 86.9 1.9 2.6 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 EMC78936.1 - 4.4e-36 122.4 52.6 8.8e-12 44.6 4.3 7.6 4 2 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EMC78936.1 - 3.2e-27 93.6 64.2 2.7e-09 36.4 0.2 9.8 5 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC78936.1 - 1.1e-08 34.8 8.4 0.00021 21.0 0.9 3.7 1 1 4 5 5 5 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC78936.1 - 3.1e-07 29.5 47.5 0.011 15.6 0.0 12.2 10 3 2 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC78936.1 - 0.0012 18.6 43.0 0.27 11.5 0.0 12.1 13 0 0 13 13 13 2 Leucine rich repeat LRR_9 PF14580.1 EMC78936.1 - 0.0025 17.4 12.1 0.19 11.3 0.2 3.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 EMC78936.1 - 0.56 10.4 0.0 0.56 10.4 0.0 10.0 11 2 1 12 12 12 0 Leucine Rich repeat DUF3733 PF12534.3 EMC78937.1 - 8.7e-55 181.9 8.6 4.6e-31 105.9 0.4 2.7 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 EMC78937.1 - 9e-35 118.2 44.5 2.8e-12 46.2 2.7 7.8 2 1 8 10 10 10 9 Leucine rich repeat LRR_4 PF12799.2 EMC78937.1 - 1.3e-28 98.0 38.2 2.4e-08 33.3 0.3 9.7 6 3 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC78937.1 - 5.5e-11 40.9 36.2 0.31 11.2 0.0 11.9 13 1 0 13 13 13 4 Leucine Rich Repeat LRR_5 PF13306.1 EMC78937.1 - 2.9e-08 33.4 9.9 0.00013 21.6 0.3 4.1 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC78937.1 - 8.1e-06 25.2 28.4 11 6.7 0.0 11.8 13 0 0 13 13 13 1 Leucine rich repeat VHL PF01847.11 EMC78937.1 - 0.08 12.4 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein DUF3733 PF12534.3 EMC78938.1 - 3.3e-50 167.2 14.3 3.6e-28 96.6 0.7 3.1 3 0 0 3 3 3 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 EMC78938.1 - 3.1e-39 132.5 34.3 5.9e-14 51.5 2.4 6.8 3 1 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EMC78938.1 - 3.7e-32 109.3 36.3 2.8e-09 36.4 0.5 8.6 8 1 1 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC78938.1 - 2.5e-15 54.1 30.6 0.018 14.9 0.1 11.6 10 1 0 10 10 10 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC78938.1 - 3.3e-11 41.4 32.3 0.097 12.9 0.4 12.0 12 1 0 12 12 12 3 Leucine rich repeat LRR_6 PF13516.1 EMC78938.1 - 0.00028 20.6 29.7 0.4 10.8 0.0 9.5 10 0 0 10 10 10 1 Leucine Rich repeat LRR_9 PF14580.1 EMC78938.1 - 0.00088 18.8 9.5 0.035 13.6 0.3 3.3 1 1 2 3 3 3 2 Leucine-rich repeat AKAP95 PF04988.7 EMC78939.1 - 2.2e-69 232.4 11.9 3.8e-69 231.6 8.3 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-Di19 PF05605.7 EMC78939.1 - 0.071 13.2 8.4 0.18 11.9 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EMC78939.1 - 0.12 12.6 7.2 0.21 11.8 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EMC78939.1 - 0.13 12.3 10.4 1.1 9.3 1.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sec63 PF02889.11 EMC78940.1 - 1.2e-61 208.7 3.1 1.8e-61 208.0 2.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EMC78940.1 - 6.5e-28 97.3 0.0 4.1e-27 94.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC78940.1 - 1.1e-11 44.4 0.0 3.8e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC78940.1 - 6.9e-10 39.0 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMC78940.1 - 0.0047 17.0 0.0 0.068 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMC78940.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 EMC78941.1 - 5.1e-46 156.9 0.0 4.8e-25 88.1 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC78941.1 - 1.2e-17 63.8 0.0 6.4e-14 51.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EMC78941.1 - 0.006 16.3 0.0 0.035 13.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC78941.1 - 0.018 13.9 0.2 7.7 5.3 0.0 2.9 3 0 0 3 3 3 0 Kinase-like Zona_pellucida PF00100.18 EMC78942.1 - 3.2e-44 151.3 0.3 6e-44 150.4 0.2 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Bromodomain PF00439.20 EMC78943.1 - 9.3e-12 44.7 0.3 2.6e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Lsr2 PF11774.3 EMC78943.1 - 0.014 15.3 0.5 0.014 15.3 0.4 2.4 2 0 0 2 2 2 0 Lsr2 Nop25 PF09805.4 EMC78943.1 - 2.4 8.2 29.9 0.082 12.9 4.2 3.3 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) Abhydrolase_6 PF12697.2 EMC78944.1 - 1.9e-35 122.8 0.0 2.5e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC78944.1 - 2.2e-22 79.7 0.0 2.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC78944.1 - 2.6e-14 53.2 0.0 4.3e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMC78944.1 - 0.0002 19.9 0.0 0.0037 15.7 0.0 2.0 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 EMC78944.1 - 0.00064 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EMC78944.1 - 0.0053 16.3 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EMC78944.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) BTB PF00651.26 EMC78945.1 - 1.9e-23 82.5 0.0 1.3e-21 76.6 0.0 2.0 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 EMC78945.1 - 0.11 12.3 0.1 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF4596 PF15363.1 EMC78946.1 - 1.6e-27 95.1 6.2 1.6e-27 95.1 4.3 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4596) DUF4580 PF15162.1 EMC78947.1 - 5.1e-45 152.7 0.3 5.8e-45 152.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) Kinetochor_Ybp2 PF08568.5 EMC78948.1 - 1.3e-89 301.2 20.7 1.6e-89 300.9 14.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-AD PF07776.10 EMC78948.1 - 0.031 14.2 0.1 0.031 14.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) RPAP2_Rtr1 PF04181.8 EMC78949.1 - 1.5e-25 89.0 4.8 1.5e-25 89.0 3.3 2.2 2 0 0 2 2 2 1 Rtr1/RPAP2 family L31 PF09784.4 EMC78949.1 - 0.068 13.2 0.2 1 9.4 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF4181 PF13789.1 EMC78949.1 - 0.11 12.4 1.2 4.3 7.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) zf-H2C2_2 PF13465.1 EMC78950.1 - 2e-31 106.7 41.7 1.7e-06 28.0 1.4 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC78950.1 - 2.2e-28 96.8 48.3 8.1e-06 25.8 0.7 6.8 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC78950.1 - 1.5e-24 84.4 32.9 0.00041 20.4 0.1 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC78950.1 - 1.1e-17 63.6 16.7 0.012 15.7 0.0 6.5 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC78950.1 - 2.2e-11 43.2 31.3 0.00021 21.0 1.0 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 EMC78950.1 - 2e-08 34.1 26.7 0.0072 16.5 0.3 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type C1_1 PF00130.17 EMC78950.1 - 0.0001 21.9 21.9 0.044 13.5 2.9 3.6 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 EMC78950.1 - 0.00041 20.0 29.1 0.011 15.4 0.4 5.9 5 1 1 6 6 6 2 BED zinc finger Prok-RING_1 PF14446.1 EMC78950.1 - 0.0014 18.3 14.0 7 6.4 0.0 6.2 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 Ta0938 PF11494.3 EMC78950.1 - 0.0024 17.9 0.7 0.39 10.8 0.0 2.6 2 1 0 2 2 2 1 Ta0938 zf-Di19 PF05605.7 EMC78950.1 - 0.0049 16.9 22.5 0.4 10.8 2.5 4.7 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EMC78950.1 - 0.062 12.9 6.7 5.4 6.6 0.0 4.2 2 2 2 4 4 4 0 GAGA factor zf-CHCC PF10276.4 EMC78950.1 - 0.082 12.7 0.2 0.082 12.7 0.1 4.5 5 0 0 5 5 4 0 Zinc-finger domain FYVE PF01363.16 EMC78950.1 - 0.2 11.5 26.9 4.9 7.1 5.9 4.2 1 1 3 4 4 4 0 FYVE zinc finger BolA PF01722.13 EMC78950.1 - 0.51 10.3 6.0 3.6 7.6 0.3 3.4 2 2 1 3 3 3 0 BolA-like protein Ribosomal_S27e PF01667.12 EMC78950.1 - 0.81 9.2 10.3 0.54 9.8 0.1 4.5 4 1 1 5 5 5 0 Ribosomal protein S27 zf-C2HC_2 PF13913.1 EMC78950.1 - 1.7 8.3 27.1 2.1 8.1 0.6 5.8 6 0 0 6 6 5 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EMC78950.1 - 1.8 8.7 24.0 24 5.1 0.3 5.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EMC78950.1 - 2.2 7.7 13.8 2.6 7.5 0.2 5.1 3 1 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 EMC78950.1 - 2.4 8.1 30.9 11 6.1 4.1 6.3 4 2 2 6 6 5 0 Zinc ribbon domain Arc_trans_TRASH PF08394.5 EMC78950.1 - 3.5 7.8 10.0 18 5.5 0.1 4.6 4 1 0 4 4 4 0 Archaeal TRASH domain Elf1 PF05129.8 EMC78950.1 - 3.6 7.3 18.6 2.4 7.9 1.9 3.7 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like HypA PF01155.14 EMC78950.1 - 4 7.1 11.4 15 5.3 0.9 3.3 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family RabGAP-TBC PF00566.13 EMC78951.1 - 4.3e-52 176.6 2.2 4.3e-52 176.6 1.5 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4224 PF13986.1 EMC78951.1 - 0.05 13.1 0.2 0.15 11.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF1129 PF06570.6 EMC78951.1 - 0.059 12.6 0.2 0.059 12.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Surfac_D-trimer PF09006.6 EMC78951.1 - 0.12 12.0 7.5 12 5.7 0.1 4.6 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation DUF2730 PF10805.3 EMC78951.1 - 3 7.6 30.6 0.14 11.8 2.1 5.2 3 1 2 5 5 5 0 Protein of unknown function (DUF2730) Ribosomal_L18p PF00861.17 EMC78952.1 - 6.9e-46 155.3 0.1 1.3e-45 154.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EMC78952.1 - 8.3e-36 122.4 8.3 1.7e-35 121.4 5.7 1.5 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF1476 PF07345.6 EMC78952.1 - 0.0031 17.7 0.4 0.0065 16.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1476) PIP49_C PF12260.3 EMC78953.1 - 1.1e-57 194.4 0.1 1.8e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 EMC78953.1 - 2.1e-33 115.2 2.3 1.1e-32 112.9 0.0 2.2 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 Mtf2_C PF14061.1 EMC78954.1 - 1.2e-29 101.9 0.1 2.5e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD PF00628.24 EMC78954.1 - 8.1e-17 60.6 28.2 9.1e-12 44.4 5.6 2.4 2 0 0 2 2 2 2 PHD-finger DUF4537 PF15057.1 EMC78954.1 - 0.0021 17.8 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EMC78954.1 - 0.0047 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Prok-RING_1 PF14446.1 EMC78954.1 - 0.0071 16.0 3.9 0.0071 16.0 2.7 3.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 EMC78954.1 - 0.012 15.2 1.3 0.012 15.2 0.9 3.0 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Chromo PF00385.19 EMC78954.1 - 0.062 12.9 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF3682 PF12446.3 EMC78954.1 - 0.074 13.3 2.6 0.14 12.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PHD_2 PF13831.1 EMC78954.1 - 3.7 6.9 22.9 0.17 11.1 4.8 3.3 2 1 0 2 2 2 0 PHD-finger EMP24_GP25L PF01105.19 EMC78955.1 - 9.7e-25 87.3 0.1 1.1e-24 87.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3110 PF11360.3 EMC78955.1 - 0.13 12.0 0.1 0.38 10.6 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3110) Reo_sigmaC PF04582.7 EMC78956.1 - 0.21 10.7 48.9 0.017 14.2 2.2 7.0 3 1 1 7 7 7 0 Reovirus sigma C capsid protein adh_short PF00106.20 EMC78957.1 - 1.7e-24 86.5 0.0 1.5e-23 83.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC78957.1 - 8.1e-09 35.3 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC78957.1 - 1.2e-05 25.2 0.0 5.6e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMC78957.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMC78957.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding DUF3015 PF11220.3 EMC78957.1 - 0.097 12.2 0.1 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) CBFD_NFYB_HMF PF00808.18 EMC78958.1 - 2.4e-23 81.9 2.4 3.6e-23 81.4 0.5 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC78958.1 - 9.4e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EMC78958.1 - 0.099 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SH2 PF00017.19 EMC78959.1 - 1.2e-15 57.0 0.0 3.1e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.14 EMC78959.1 - 8.5e-13 48.4 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Fcf2 PF08698.6 EMC78960.1 - 3.6e-34 116.7 0.2 3.6e-34 116.7 0.1 2.8 3 1 0 3 3 3 1 Fcf2 pre-rRNA processing Aldo_ket_red PF00248.16 EMC78961.1 - 6.3e-07 28.4 0.0 7.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Steroid_dh PF02544.11 EMC78962.1 - 1e-26 93.4 5.5 1.9e-26 92.5 3.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase RhoGAP PF00620.22 EMC78963.1 - 7.9e-50 168.4 0.5 7.9e-50 168.4 0.3 2.3 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.17 EMC78963.1 - 1.2e-06 28.1 9.2 2.9e-06 26.9 6.4 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ABC_membrane_2 PF06472.10 EMC78964.1 - 9.7e-102 339.8 6.8 1.3e-101 339.4 4.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMC78964.1 - 8.4e-18 64.9 0.0 1.8e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC78964.1 - 0.00014 21.9 1.5 0.0047 16.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EMC78964.1 - 0.00093 19.5 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EMC78964.1 - 0.0013 18.0 0.0 0.19 10.9 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMC78964.1 - 0.0067 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMC78964.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EMC78964.1 - 0.086 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 EMC78964.1 - 0.097 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EMC78964.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Interfer-bind PF09294.5 EMC78965.1 - 2.9e-22 78.7 1.0 2.1e-21 75.9 0.1 2.1 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 EMC78965.1 - 4.9e-20 71.2 0.2 1.1e-19 70.0 0.2 1.6 1 0 0 1 1 1 1 Tissue factor Sarcoglycan_2 PF05510.8 EMC78965.1 - 0.028 12.7 0.0 0.056 11.7 0.0 1.4 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF912 PF06024.7 EMC78965.1 - 0.03 14.3 1.4 0.057 13.4 0.9 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 EMC78965.1 - 0.13 12.6 0.9 0.43 11.0 0.7 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EMC78965.1 - 0.13 11.9 4.8 0.035 13.8 1.1 1.8 2 1 0 2 2 2 0 TMEM154 protein family IncA PF04156.9 EMC78965.1 - 0.17 11.5 0.6 0.55 9.7 0.1 1.8 2 0 0 2 2 2 0 IncA protein Choline_transpo PF04515.7 EMC78966.1 - 3.5e-88 295.5 31.2 3.5e-88 295.5 21.6 2.0 3 0 0 3 3 3 1 Plasma-membrane choline transporter DUF4131 PF13567.1 EMC78966.1 - 0.0027 17.1 8.3 0.0027 17.1 5.8 4.5 3 1 2 5 5 5 1 Domain of unknown function (DUF4131) PDR_CDR PF06422.7 EMC78966.1 - 0.24 11.1 3.1 16 5.1 0.1 3.1 2 0 0 2 2 2 0 CDR ABC transporter KdpC PF02669.10 EMC78966.1 - 0.26 10.9 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Calponin PF00402.13 EMC78968.1 - 2.5e-39 132.2 13.0 3.8e-14 51.6 0.8 3.6 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.26 EMC78968.1 - 9.2e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC78968.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.6 EMC78968.1 - 0.11 12.5 0.1 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin Alg14 PF08660.6 EMC78969.1 - 1.4e-64 217.2 0.0 1.5e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TRAM_LAG1_CLN8 PF03798.11 EMC78970.1 - 3.3e-40 137.7 16.4 3.3e-40 137.7 11.4 1.5 2 0 0 2 2 2 1 TLC domain DUF3007 PF11460.3 EMC78970.1 - 0.28 11.2 3.8 0.34 11.0 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3007) Cyto_heme_lyase PF01265.12 EMC78971.1 - 2.6e-90 302.5 4.1 3.6e-90 302.0 2.8 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Retinal PF15449.1 EMC78971.1 - 1.2 6.6 10.3 1.6 6.3 7.1 1.1 1 0 0 1 1 1 0 Retinal protein DUF1115 PF06544.7 EMC78972.1 - 1.6e-09 37.5 0.4 2e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DHO_dh PF01180.16 EMC78973.1 - 1.2e-35 122.9 0.0 1.2e-34 119.6 0.0 2.2 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.1 EMC78973.1 - 2.7e-23 81.5 12.1 2.7e-23 81.5 8.4 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_20 PF14691.1 EMC78973.1 - 2.6e-12 46.3 0.0 2.6e-12 46.3 0.0 2.5 2 1 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.1 EMC78973.1 - 3.5e-08 33.3 0.0 1.1e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC78973.1 - 1.1e-07 31.9 0.0 0.16 11.8 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.12 EMC78973.1 - 5.2e-07 28.7 0.1 9.8e-06 24.6 0.1 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.2 EMC78973.1 - 2.2e-06 27.9 10.2 2.2e-06 27.9 7.0 2.4 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMC78973.1 - 2.4e-06 27.2 10.5 2.4e-06 27.2 7.3 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.22 EMC78973.1 - 1.2e-05 24.6 20.8 0.0049 16.4 3.2 4.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 EMC78973.1 - 0.00024 21.3 13.0 0.00024 21.3 9.0 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 EMC78973.1 - 0.00028 21.2 0.1 1.5 9.2 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.2 EMC78973.1 - 0.00045 19.9 1.8 0.00045 19.9 1.2 3.3 3 1 0 3 3 2 2 4Fe-4S binding domain Pyr_redox_3 PF13738.1 EMC78973.1 - 0.0012 18.9 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.2 EMC78973.1 - 0.0047 16.7 24.4 0.0089 15.9 1.9 3.4 2 1 1 3 3 2 2 4Fe-4S binding domain Thi4 PF01946.12 EMC78973.1 - 0.021 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family PcrB PF01884.12 EMC78973.1 - 0.027 13.7 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 PcrB family Fer4_13 PF13370.1 EMC78973.1 - 0.028 14.8 13.0 0.27 11.6 2.1 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Shikimate_DH PF01488.15 EMC78973.1 - 0.029 14.4 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer4_15 PF13459.1 EMC78973.1 - 0.047 14.2 9.1 0.8 10.3 0.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain FAD_oxidored PF12831.2 EMC78973.1 - 0.085 11.9 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fer4_4 PF12800.2 EMC78973.1 - 0.91 10.0 24.1 0.13 12.6 1.5 3.6 3 1 0 3 3 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 EMC78973.1 - 0.99 9.4 23.0 0.036 14.0 3.0 3.0 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 EMC78973.1 - 1.1 9.6 16.4 0.47 10.8 0.8 3.0 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMC78973.1 - 3.7 8.0 17.7 2.2 8.7 1.8 3.4 3 0 0 3 3 3 0 4Fe-4S dicluster domain PX PF00787.19 EMC78974.1 - 2.5e-25 88.4 0.8 4.7e-25 87.5 0.5 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EMC78974.1 - 2.3e-06 27.0 4.2 0.0033 16.7 0.0 2.5 2 1 1 3 3 3 2 Vps5 C terminal like NuA4 PF09340.5 EMC78974.1 - 0.15 11.7 0.8 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 BAR PF03114.13 EMC78974.1 - 0.18 11.2 2.4 1.5 8.2 1.7 2.0 1 1 0 1 1 1 0 BAR domain P4Ha_N PF08336.6 EMC78974.1 - 0.54 10.0 2.9 2.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PAP2 PF01569.16 EMC78975.1 - 1.8e-16 60.0 2.5 2.4e-16 59.5 1.7 1.1 1 0 0 1 1 1 1 PAP2 superfamily Cyto_ox_2 PF02322.10 EMC78975.1 - 0.0017 17.5 0.4 0.0026 16.9 0.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase subunit II SLAC1 PF03595.12 EMC78975.1 - 0.01 14.5 0.3 0.016 13.8 0.2 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel Syndecan PF01034.15 EMC78975.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain YjgP_YjgQ PF03739.9 EMC78975.1 - 0.091 11.4 0.2 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1191 PF06697.7 EMC78975.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF998 PF06197.8 EMC78975.1 - 0.13 11.5 3.8 0.13 11.5 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF998) PAP2 PF01569.16 EMC78976.1 - 2.2e-14 53.2 1.2 3.5e-14 52.5 0.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PTH2 PF01981.11 EMC78976.1 - 0.19 11.4 0.9 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Peptidyl-tRNA hydrolase PTH2 Paralemmin PF03285.10 EMC78977.1 - 2.6e-23 82.8 21.9 8.4e-12 45.1 11.4 3.1 2 2 0 2 2 2 2 Paralemmin PilJ PF13675.1 EMC78977.1 - 0.0012 19.0 1.2 0.0032 17.7 0.8 1.7 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3573 PF12097.3 EMC78977.1 - 0.4 9.2 1.7 0.6 8.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med22 PF06179.7 EMC78977.1 - 2.7 8.0 13.4 0.22 11.5 1.5 3.6 2 1 1 3 3 3 0 Surfeit locus protein 5 subunit 22 of Mediator complex Nup54 PF13874.1 EMC78977.1 - 4.9 6.8 19.5 0.38 10.4 9.3 2.2 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Reeler PF02014.11 EMC78978.1 - 5.1e-33 114.1 0.0 7.6e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.12 EMC78978.1 - 9.4e-22 77.2 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EMC78978.1 - 0.00064 19.5 11.8 0.0014 18.4 8.2 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 EMC78978.1 - 0.038 13.7 5.5 0.063 13.0 3.2 1.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Nuc_sug_transp PF04142.10 EMC78979.1 - 5.8e-93 310.4 14.3 1.3e-92 309.3 9.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EMC78979.1 - 3.6e-05 23.4 1.1 3.6e-05 23.4 0.7 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EMC78979.1 - 3.8e-05 23.7 4.4 3.8e-05 23.7 3.1 2.7 2 2 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EMC78979.1 - 0.0011 19.1 2.5 0.0011 19.1 1.8 3.1 2 2 1 3 3 3 1 Multidrug resistance efflux transporter DUF4131 PF13567.1 EMC78979.1 - 5.3 6.4 7.5 18 4.6 3.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 EMC78980.1 - 1.6e-33 115.9 37.7 3.2e-32 111.6 26.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Tropomyosin_1 PF12718.2 EMC78981.1 - 0.0012 18.6 14.5 0.0012 18.6 10.0 4.8 1 1 4 5 5 5 1 Tropomyosin like Spc42p PF11544.3 EMC78981.1 - 0.015 15.2 5.1 0.015 15.2 3.5 5.5 2 2 2 5 5 5 0 Spindle pole body component Spc42p Reo_sigmaC PF04582.7 EMC78981.1 - 1.1 8.3 23.5 0.18 10.9 0.9 4.0 1 1 4 5 5 5 0 Reovirus sigma C capsid protein IncA PF04156.9 EMC78981.1 - 2.6 7.6 81.9 0.35 10.4 19.7 3.6 1 1 2 3 3 3 0 IncA protein IFT57 PF10498.4 EMC78981.1 - 2.9 6.5 64.2 0.53 8.9 17.5 3.1 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 TRM13 PF05206.9 EMC78982.1 - 8.1e-88 294.0 2.9 1.2e-87 293.4 2.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 EMC78982.1 - 3.1e-14 52.0 2.0 3.1e-14 52.0 1.4 2.9 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 EMC78982.1 - 1.2e-10 40.8 1.3 2.7e-10 39.7 0.9 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 EMC78982.1 - 0.019 14.6 0.2 0.019 14.6 0.2 2.4 2 0 0 2 2 2 0 Methyltransferase domain LRR_8 PF13855.1 EMC78983.1 - 5.7e-39 131.6 31.0 7.6e-13 48.0 1.7 4.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EMC78983.1 - 8e-37 124.2 27.7 7.8e-13 47.7 2.7 6.7 2 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC78983.1 - 1.6e-21 73.0 20.2 0.085 12.9 0.1 8.8 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_6 PF13516.1 EMC78983.1 - 9.3e-13 46.8 12.2 0.11 12.6 0.1 7.8 8 0 0 8 8 8 5 Leucine Rich repeat LRR_7 PF13504.1 EMC78983.1 - 8.7e-11 40.2 19.9 0.59 10.5 0.2 8.5 9 0 0 9 9 9 4 Leucine rich repeat LRR_9 PF14580.1 EMC78983.1 - 0.0014 18.1 6.8 0.14 11.7 0.5 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_3 PF07725.7 EMC78983.1 - 3.1 7.7 8.1 17 5.4 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat 2-oxoacid_dh PF00198.18 EMC78984.1 - 2.1e-80 269.3 0.0 3e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMC78984.1 - 2.5e-20 71.8 0.1 4.4e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EMC78984.1 - 1.1e-14 53.7 0.0 2.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EMC78984.1 - 0.006 16.2 0.1 0.19 11.4 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like PAZ_siRNAbind PF12212.3 EMC78984.1 - 0.097 12.3 0.3 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain I-set PF07679.11 EMC78985.1 - 1.2e-48 162.9 4.1 2.5e-15 56.0 0.2 5.0 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC78985.1 - 1.9e-45 152.8 5.3 2e-11 43.8 0.0 5.1 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 EMC78985.1 - 9.3e-38 128.5 13.4 7.8e-10 39.1 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 EMC78985.1 - 1e-25 89.5 5.3 3.2e-06 27.1 0.0 5.1 4 1 0 4 4 4 4 Immunoglobulin domain C2-set_2 PF08205.7 EMC78985.1 - 1.7e-16 59.8 7.5 0.0018 18.1 0.0 5.8 5 1 0 5 5 5 4 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC78985.1 - 4.8e-16 58.6 13.3 8e-06 25.7 0.2 7.6 3 3 1 4 4 4 3 Immunoglobulin V-set domain C2-set PF05790.10 EMC78985.1 - 1.8e-12 47.0 5.5 2.5e-09 36.9 0.0 4.3 5 0 0 5 5 5 2 Immunoglobulin C2-set domain C1-set PF07654.10 EMC78985.1 - 0.003 17.5 0.3 0.54 10.2 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.6 EMC78985.1 - 0.0069 16.1 0.3 3 7.6 0.0 3.6 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.3 EMC78985.1 - 0.043 13.7 0.1 7.1 6.5 0.0 3.2 3 1 0 3 3 3 0 Natural killer cell receptor 2B4 DSPn PF14671.1 EMC78986.1 - 8.3e-60 200.8 3.0 1.6e-59 199.9 1.2 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EMC78986.1 - 5e-15 55.2 0.0 1.9e-14 53.4 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC78986.1 - 3.9e-06 26.9 0.0 7.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EMC78986.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC78986.1 - 0.00036 20.8 0.0 0.00082 19.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_transf_64 PF09258.5 EMC78987.1 - 8.7e-85 283.8 0.0 1.1e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.21 EMC78987.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 TP_methylase PF00590.15 EMC78988.1 - 6e-21 75.1 0.0 1.3e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Aldo_ket_red PF00248.16 EMC78989.1 - 1.4e-60 204.5 0.0 1.8e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 7tm_1 PF00001.16 EMC78990.1 - 3.4e-44 150.9 23.3 4.4e-44 150.5 14.6 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC78990.1 - 3.3e-05 23.1 23.4 4.4e-05 22.7 16.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC78990.1 - 0.00021 20.5 25.4 0.0033 16.5 16.1 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv EVC2_like PF12297.3 EMC78990.1 - 0.13 10.8 0.5 0.21 10.1 0.4 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein OLF PF02191.11 EMC78991.1 - 1.2e-92 309.7 6.5 1.7e-92 309.2 4.5 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 EMC78991.1 - 4.9e-42 141.8 2.8 4.9e-42 141.8 2.0 2.3 2 1 1 3 3 3 1 Neurogenesis glycoprotein DUF1216 PF06746.6 EMC78991.1 - 0.014 15.2 1.5 0.029 14.1 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) CBM_5_12_2 PF14600.1 EMC78991.1 - 0.037 13.6 0.7 0.93 9.1 0.0 2.7 2 0 0 2 2 2 0 Cellulose-binding domain MitMem_reg PF13012.1 EMC78991.1 - 0.26 11.3 4.3 2.3 8.3 2.3 2.7 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function RRM_6 PF14259.1 EMC78992.1 - 5.5e-11 42.2 0.6 6.2e-07 29.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC78992.1 - 4e-10 39.1 0.3 1.2e-06 28.0 0.2 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC78992.1 - 1.8e-07 30.8 0.1 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alpha-amylase PF00128.19 EMC78993.1 - 2.3e-22 79.8 0.0 3.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EMC78993.1 - 2.4e-12 46.8 0.3 7.8e-12 45.1 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EMC78994.1 - 1.7e-23 83.5 0.0 2.4e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EMC78994.1 - 4.7e-14 52.2 0.1 1.1e-13 51.0 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Laminin_N PF00055.12 EMC78995.1 - 2.3e-30 105.3 0.8 2.3e-30 105.3 0.6 2.4 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 EMC78995.1 - 1.9e-22 78.9 64.1 1.5e-08 34.3 7.8 5.0 3 1 1 4 4 4 3 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EMC78995.1 - 0.0011 19.1 10.7 0.0011 19.1 7.4 7.6 6 2 2 8 8 8 1 EGF-like domain EGF PF00008.22 EMC78995.1 - 0.01 15.7 10.3 0.01 15.7 7.1 6.0 6 2 0 6 6 6 0 EGF-like domain hEGF PF12661.2 EMC78995.1 - 0.014 15.4 2.2 0.014 15.4 1.5 6.3 7 0 0 7 7 7 0 Human growth factor-like EGF RhoGEF PF00621.15 EMC78996.1 - 6.2e-40 136.9 8.2 1.5e-39 135.7 5.7 1.7 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.12 EMC78996.1 - 9.7e-27 92.2 0.0 1.7e-14 53.0 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 EMC78996.1 - 1.6e-19 69.1 0.1 1.4e-12 47.0 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC78996.1 - 3e-17 61.7 0.1 1.6e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.19 EMC78996.1 - 1.4e-15 56.7 0.5 7.1e-15 54.5 0.4 2.3 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.17 EMC78996.1 - 1.4e-09 37.5 4.6 2.8e-09 36.5 3.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 EMC78996.1 - 2.1e-07 31.0 0.1 5.2e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 PH domain Filamin PF00630.14 EMC78996.1 - 0.001 19.6 0.1 0.0053 17.2 0.0 2.2 1 1 0 1 1 1 1 Filamin/ABP280 repeat Prok-RING_1 PF14446.1 EMC78996.1 - 0.025 14.2 2.1 0.062 13.0 1.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CAMSAP_CH PF11971.3 EMC78996.1 - 0.047 13.3 1.2 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain C1_2 PF03107.11 EMC78996.1 - 0.095 12.8 1.9 0.3 11.2 1.3 2.0 1 0 0 1 1 1 0 C1 domain Methyltransf_23 PF13489.1 EMC78997.1 - 6.6e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC78997.1 - 0.0046 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain fn3 PF00041.16 EMC78998.1 - 1.7e-35 120.9 7.0 1.4e-06 28.3 0.1 9.5 8 2 0 8 8 8 6 Fibronectin type III domain DUF2369 PF10179.4 EMC78998.1 - 0.00014 21.0 1.7 1.6 7.7 0.0 5.1 4 1 0 5 5 5 2 Uncharacterised conserved protein (DUF2369) Y_Y_Y PF07495.8 EMC78998.1 - 0.01 15.5 0.0 0.92 9.3 0.0 3.7 5 0 0 5 5 5 0 Y_Y_Y domain Sec1 PF00995.18 EMC78999.1 - 1.5e-133 446.4 3.7 1.7e-133 446.2 2.6 1.0 1 0 0 1 1 1 1 Sec1 family DUF2621 PF11084.3 EMC78999.1 - 0.083 12.5 0.2 0.21 11.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) MazG PF03819.12 EMC78999.1 - 0.98 9.4 4.2 0.62 10.0 0.9 2.1 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain GoLoco PF02188.12 EMC79000.1 - 2.3e-40 135.0 28.7 1.6e-10 40.0 2.3 4.5 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.1 EMC79000.1 - 2e-38 130.2 30.3 1.9e-10 40.4 3.6 5.9 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMC79000.1 - 4.2e-36 121.0 29.3 8.8e-07 28.2 0.3 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 EMC79000.1 - 3.1e-29 98.4 18.9 2.1e-05 23.9 0.2 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 EMC79000.1 - 1e-21 76.3 23.4 4.2e-07 29.5 0.6 5.5 4 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 EMC79000.1 - 4.4e-21 73.0 29.2 0.0002 21.0 0.4 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 EMC79000.1 - 1.6e-15 56.4 22.9 0.04 13.8 0.3 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC79000.1 - 5.2e-15 54.0 24.6 0.0003 20.3 0.2 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC79000.1 - 2.6e-08 33.7 5.4 0.35 11.6 0.1 6.8 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMC79000.1 - 4e-08 32.9 0.1 0.54 10.8 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC79000.1 - 2.3e-06 28.1 18.9 0.0049 17.4 0.6 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC79000.1 - 5.7e-06 26.1 17.4 4.9 7.5 0.0 7.7 6 1 1 7 7 7 2 Tetratricopeptide repeat Rapsyn_N PF10579.4 EMC79000.1 - 9.9e-06 25.2 1.2 2.8 7.7 0.0 5.1 2 2 4 6 6 6 1 Rapsyn N-terminal myristoylation and linker region Apc3 PF12895.2 EMC79000.1 - 0.00051 20.1 13.7 0.16 12.1 2.4 5.2 3 1 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC79000.1 - 0.00086 19.6 5.7 5.6 7.6 0.2 6.1 7 0 0 7 7 5 1 Tetratricopeptide repeat RPN7 PF10602.4 EMC79000.1 - 0.17 11.2 1.6 0.93 8.8 0.1 2.7 2 2 0 2 2 2 0 26S proteasome subunit RPN7 UreE_C PF05194.7 EMC79000.1 - 0.49 10.5 4.9 11 6.1 0.1 3.6 3 1 1 4 4 4 0 UreE urease accessory protein, C-terminal domain MCLC PF05934.6 EMC79001.1 - 9.7e-175 582.0 7.4 1.1e-174 581.7 5.1 1.0 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) SPC25 PF06703.6 EMC79001.1 - 0.37 10.3 6.8 0.83 9.2 2.4 2.8 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PAP2 PF01569.16 EMC79001.1 - 5.7 6.6 8.7 1.3 8.7 3.3 1.8 2 0 0 2 2 2 0 PAP2 superfamily WD40 PF00400.27 EMC79002.1 - 2.1e-42 141.5 13.2 1.1e-08 34.5 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat DEAD PF00270.24 EMC79003.1 - 1.3e-41 141.9 0.9 1.3e-41 141.9 0.6 2.2 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC79003.1 - 2.2e-20 72.2 0.1 6.9e-20 70.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-HIT PF04438.11 EMC79003.1 - 2.2e-08 33.5 1.9 3.8e-08 32.8 1.3 1.4 1 0 0 1 1 1 1 HIT zinc finger SecA_DEAD PF07517.9 EMC79003.1 - 0.0026 17.1 1.1 0.15 11.2 0.0 2.6 3 0 0 3 3 3 1 SecA DEAD-like domain ResIII PF04851.10 EMC79003.1 - 0.0047 16.7 0.0 0.033 14.0 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EMC79003.1 - 0.033 13.4 0.8 1 8.6 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 EMC79003.1 - 0.048 13.8 0.5 0.23 11.6 0.2 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CMS1 PF14617.1 EMC79003.1 - 0.13 11.2 2.1 0.21 10.6 0.1 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Kinesin PF00225.18 EMC79004.1 - 1.1e-106 356.3 0.1 1.1e-106 356.3 0.1 2.2 2 0 0 2 2 2 1 Kinesin motor domain FHA PF00498.21 EMC79004.1 - 4.6e-09 36.2 0.1 1.1e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain zf-H2C2_2 PF13465.1 EMC79005.1 - 2.2e-21 75.0 20.5 2.1e-06 27.7 0.1 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79005.1 - 4.4e-12 45.5 36.2 0.0039 17.4 0.7 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79005.1 - 5.7e-08 32.5 29.7 0.014 15.6 3.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger RRN7 PF11781.3 EMC79005.1 - 0.42 10.1 3.1 31 4.1 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1595 PF12760.2 EMC79005.1 - 0.98 9.2 13.3 0.14 11.9 1.6 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.6 EMC79005.1 - 1.3 8.6 9.7 0.15 11.6 1.3 2.9 1 1 1 3 3 3 0 GAGA factor zf-C2H2_6 PF13912.1 EMC79005.1 - 8.7 6.4 24.3 0.16 11.9 0.9 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger Hormone_recep PF00104.25 EMC79006.1 - 5.7e-33 113.7 4.7 8.9e-33 113.1 3.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC79006.1 - 2.2e-32 111.0 12.0 3.7e-32 110.3 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Y_phosphatase PF00102.22 EMC79007.1 - 6.4e-79 264.6 0.9 1e-78 263.9 0.6 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC79007.1 - 0.0016 18.7 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Exonuc_VIII PF06630.6 EMC79007.1 - 0.12 11.6 1.3 0.29 10.4 0.9 1.6 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Y_phosphatase PF00102.22 EMC79008.1 - 9.3e-81 270.6 0.0 1.3e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC79008.1 - 0.0074 16.3 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 EMC79008.1 - 0.0094 15.5 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC79008.1 - 0.015 15.5 0.0 0.051 13.8 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family V-ATPase_G PF03179.10 EMC79009.1 - 1.6e-27 95.8 8.9 1.9e-27 95.5 6.2 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit VWA_N PF08399.6 EMC79009.1 - 0.012 16.1 0.4 0.015 15.9 0.3 1.1 1 0 0 1 1 1 0 VWA N-terminal DUF773 PF05600.7 EMC79009.1 - 0.026 13.3 2.6 0.029 13.1 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) FdhE PF04216.7 EMC79009.1 - 0.037 13.7 0.6 0.039 13.6 0.4 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Baculo_p24 PF05073.7 EMC79009.1 - 0.086 12.4 1.8 0.11 12.1 1.3 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF2392 PF10288.4 EMC79009.1 - 0.1 12.9 0.5 0.13 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Cor1 PF04803.7 EMC79009.1 - 0.15 11.8 6.7 0.25 11.0 4.6 1.5 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region FTO_CTD PF12934.2 EMC79009.1 - 0.17 11.4 2.0 0.35 10.4 1.4 1.6 1 1 0 1 1 1 0 FTO C-terminal domain Ribosomal_L20 PF00453.13 EMC79009.1 - 0.22 11.4 3.4 0.27 11.1 1.1 1.9 1 1 1 2 2 2 0 Ribosomal protein L20 7TMR-HDED PF07697.6 EMC79009.1 - 0.28 10.8 4.2 0.5 10.0 2.9 1.4 1 1 0 1 1 1 0 7TM-HD extracellular DUF342 PF03961.8 EMC79009.1 - 0.88 7.9 5.8 1 7.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3552 PF12072.3 EMC79009.1 - 0.9 8.7 12.0 1.8 7.7 8.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF106 PF01956.11 EMC79009.1 - 1.2 8.5 4.3 1.7 8.1 3.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Atg14 PF10186.4 EMC79009.1 - 6.6 5.5 8.6 7.5 5.3 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_B PF00430.13 EMC79009.1 - 9.5 6.0 10.6 28 4.5 7.0 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Pkinase PF00069.20 EMC79010.1 - 2.1e-67 226.9 0.0 2.6e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79010.1 - 1.9e-48 164.8 0.0 2.3e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79010.1 - 2.5e-08 33.2 0.0 3.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.3 EMC79010.1 - 0.0093 15.4 0.2 0.43 9.9 0.1 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Kdo PF06293.9 EMC79010.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RMMBL PF07521.7 EMC79010.1 - 0.018 14.8 0.1 0.88 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase LIM PF00412.17 EMC79011.1 - 1.3e-32 111.6 21.3 9.4e-17 60.8 2.4 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 EMC79011.1 - 3.4e-19 68.1 3.5 7.2e-19 67.1 2.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79011.1 - 0.00043 19.9 3.0 0.0018 17.9 2.0 2.0 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC79011.1 - 0.01 14.8 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DENN PF02141.16 EMC79012.1 - 1.3e-48 165.1 3.6 2.2e-48 164.4 2.5 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EMC79012.1 - 1.8e-18 66.3 0.1 5.5e-18 64.7 0.0 1.9 1 0 0 1 1 1 1 dDENN domain SPA PF08616.5 EMC79012.1 - 0.1 12.3 0.2 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis EGF PF00008.22 EMC79013.1 - 4.5e-94 307.7 271.8 8.9e-08 31.9 2.5 19.8 19 1 0 19 19 19 17 EGF-like domain Laminin_G_2 PF02210.19 EMC79013.1 - 1.1e-52 177.4 1.2 4e-20 72.1 0.1 3.6 4 0 0 4 4 4 3 Laminin G domain Laminin_G_1 PF00054.18 EMC79013.1 - 1.4e-39 135.1 0.1 2.2e-15 56.8 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain EGF_CA PF07645.10 EMC79013.1 - 1.8e-20 72.6 257.5 1.3e-05 25.0 3.9 19.7 16 3 4 20 20 20 12 Calcium-binding EGF domain hEGF PF12661.2 EMC79013.1 - 1.6e-16 59.1 169.5 0.0022 17.9 2.6 18.0 18 0 0 18 18 18 11 Human growth factor-like EGF EGF_2 PF07974.8 EMC79013.1 - 5e-13 48.9 299.0 0.0015 18.6 6.2 19.3 19 0 0 19 19 19 16 EGF-like domain Laminin_G_3 PF13385.1 EMC79013.1 - 5.7e-06 26.6 0.0 0.027 14.6 0.0 3.3 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily zf-H2C2_2 PF13465.1 EMC79014.1 - 1.7e-52 173.2 126.0 4.3e-07 29.9 0.5 15.3 16 0 0 16 16 16 13 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79014.1 - 4.3e-47 155.6 132.7 6.1e-05 23.1 2.3 14.7 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79014.1 - 6.1e-35 116.9 126.2 0.00097 19.3 0.6 15.1 15 0 0 15 15 15 13 C2H2-type zinc finger BTB PF00651.26 EMC79014.1 - 2.2e-21 75.9 0.7 6.4e-21 74.4 0.5 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.2 EMC79014.1 - 9.9e-10 38.2 86.5 0.00041 20.4 0.8 14.0 14 0 0 14 14 14 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC79014.1 - 4.9e-09 35.7 102.6 0.00052 19.8 0.7 13.7 14 0 0 14 14 14 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79014.1 - 5.6e-08 32.7 85.8 0.059 13.5 0.0 14.1 14 0 0 14 14 14 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EMC79014.1 - 0.012 15.2 15.7 4.1 7.0 0.1 6.4 3 2 3 6 6 6 0 GAGA factor zf-C2H2_2 PF12756.2 EMC79014.1 - 0.016 15.3 82.6 0.042 13.9 2.7 13.2 3 1 8 12 12 12 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EMC79014.1 - 0.077 12.6 0.2 0.067 12.8 1.3 12.2 14 1 0 14 14 14 0 zinc-finger of a C2HC-type Sushi PF00084.15 EMC79015.1 - 1.4e-48 163.0 63.8 5e-09 36.3 1.5 9.3 8 1 1 9 9 9 9 Sushi domain (SCR repeat) Sushi_2 PF09014.5 EMC79015.1 - 0.0014 18.3 26.5 0.006 16.3 0.7 6.5 5 3 2 7 7 7 2 Beta-2-glycoprotein-1 fifth domain cEGF PF12662.2 EMC79015.1 - 0.91 9.2 15.0 3.5 7.3 0.4 5.1 4 0 0 4 4 4 0 Complement Clr-like EGF-like Galactosyl_T PF01762.16 EMC79016.1 - 8.2e-66 221.3 0.0 1.2e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Glutaredoxin PF00462.19 EMC79017.1 - 2.8e-20 72.0 0.1 3.5e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EMC79017.1 - 5.2e-05 22.9 0.1 7.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 EMC79017.1 - 0.00068 19.8 0.0 0.00092 19.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EMC79017.1 - 0.0022 18.1 0.7 0.0031 17.7 0.5 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2117 PF09890.4 EMC79017.1 - 0.0045 16.2 0.0 0.0051 16.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2117) DSBA PF01323.15 EMC79017.1 - 0.0085 15.6 0.5 0.2 11.2 0.0 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 EMC79017.1 - 0.0091 15.9 0.1 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EMC79017.1 - 0.044 13.2 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EMC79017.1 - 0.1 12.6 1.0 8.3 6.3 0.4 2.1 1 1 0 2 2 2 0 Thioredoxin GST_N_3 PF13417.1 EMC79017.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TROVE PF05731.6 EMC79018.1 - 4.9e-105 351.4 0.2 5.9e-105 351.1 0.2 1.1 1 0 0 1 1 1 1 TROVE domain DUF2201 PF09967.4 EMC79018.1 - 2.8e-06 27.3 0.3 6.6e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 VWA-like domain (DUF2201) VWA_CoxE PF05762.9 EMC79018.1 - 0.031 13.4 1.1 0.1 11.7 0.8 1.8 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein VWA_2 PF13519.1 EMC79018.1 - 0.051 13.6 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_C12 PF01088.16 EMC79019.1 - 8.1e-63 211.4 0.0 8.1e-63 211.4 0.0 1.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Kinesin-relat_1 PF12711.2 EMC79019.1 - 1 9.8 9.1 0.52 10.7 4.0 2.1 1 1 1 2 2 2 0 Kinesin motor RGS PF00615.14 EMC79020.1 - 1.7e-39 134.5 7.8 1.7e-39 134.5 5.4 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS PF00615.14 EMC79021.1 - 1.3e-34 118.7 1.9 1.6e-34 118.5 1.3 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.6 EMC79021.1 - 0.016 14.7 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain RloB PF13707.1 EMC79021.1 - 0.02 14.5 0.5 0.022 14.4 0.3 1.1 1 0 0 1 1 1 0 RloB-like protein SpoOE-like PF09388.5 EMC79021.1 - 0.077 12.5 0.1 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein RGS PF00615.14 EMC79022.1 - 3.4e-37 127.1 3.1 5.1e-37 126.5 2.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rod-binding PF10135.4 EMC79022.1 - 0.12 12.3 0.5 3.1 7.8 0.1 2.6 3 0 0 3 3 3 0 Rod binding protein RGS PF00615.14 EMC79023.1 - 5.7e-39 132.8 2.4 6.8e-39 132.6 1.6 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 EMC79024.1 - 1.5e-38 131.5 3.5 2.1e-38 131.0 2.4 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.6 EMC79024.1 - 0.003 17.0 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RGS PF00615.14 EMC79025.1 - 2.1e-37 127.8 1.9 2.7e-37 127.4 1.3 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 EMC79026.1 - 2.2e-38 130.9 2.5 2.9e-38 130.5 1.7 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gag_p19 PF02228.11 EMC79026.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Major core protein p19 PI-PLC-X PF00388.14 EMC79027.1 - 5e-08 32.4 0.0 1.1e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Sushi PF00084.15 EMC79028.1 - 3.6e-79 261.0 87.7 9.6e-10 38.6 0.7 10.3 9 1 1 10 10 10 9 Sushi domain (SCR repeat) Lectin_C PF00059.16 EMC79028.1 - 1.5e-21 77.0 5.8 1.5e-21 77.0 4.0 4.0 6 0 0 6 6 6 1 Lectin C-type domain EGF PF00008.22 EMC79028.1 - 2.2e-07 30.7 8.5 1.4e-05 24.9 5.9 4.5 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.2 EMC79028.1 - 0.00036 20.1 3.2 0.00036 20.1 2.3 10.8 10 1 0 10 10 10 4 Complement Clr-like EGF-like EGF_2 PF07974.8 EMC79028.1 - 0.00078 19.5 14.1 0.0042 17.2 7.1 4.8 2 0 0 2 2 2 1 EGF-like domain EGF_3 PF12947.2 EMC79028.1 - 0.0096 15.8 2.0 0.0096 15.8 1.4 6.8 10 2 0 10 10 10 1 EGF domain HRM PF02793.17 EMC79028.1 - 1.4 9.0 70.8 1.7 8.7 0.7 10.0 9 1 1 10 10 10 0 Hormone receptor domain bZIP_1 PF00170.16 EMC79029.1 - 3e-10 39.9 12.7 6.1e-10 38.9 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC79029.1 - 5.2e-06 26.1 13.0 5.2e-06 26.1 9.0 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC79029.1 - 0.0022 18.2 8.5 0.0022 18.2 5.9 2.8 3 0 0 3 3 3 1 bZIP Maf transcription factor DUF972 PF06156.8 EMC79029.1 - 4.1 7.8 6.1 2.3 8.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) OLF PF02191.11 EMC79030.1 - 3.6e-91 304.8 9.8 4.9e-91 304.4 6.8 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 EMC79030.1 - 0.011 15.4 0.6 0.049 13.4 0.0 2.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein adh_short PF00106.20 EMC79031.1 - 0.0015 18.5 0.0 0.008 16.1 0.0 2.3 2 1 1 3 3 3 1 short chain dehydrogenase Pkinase_Tyr PF07714.12 EMC79032.1 - 1.3e-84 283.2 0.0 1.7e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC79032.1 - 4e-44 150.7 0.0 7.1e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Herpes_gE PF02480.11 EMC79032.1 - 0.00063 18.1 0.0 0.00093 17.5 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 EMC79032.1 - 0.015 15.5 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3827 PF12877.2 EMC79032.1 - 0.59 8.1 2.5 0.97 7.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) F5_F8_type_C PF00754.20 EMC79033.1 - 5.9e-16 58.4 0.0 7.1e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain UDPGP PF01704.13 EMC79034.1 - 3.3e-87 292.7 0.0 4.1e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase PF00069.20 EMC79035.1 - 7.6e-35 120.3 0.0 9.3e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79035.1 - 6.3e-17 61.5 0.1 8.3e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_5 PF13893.1 EMC79035.1 - 2e-08 33.9 0.0 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC79035.1 - 5.8e-08 32.2 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinase-like PF14531.1 EMC79035.1 - 5e-07 28.9 0.0 6.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RRM_6 PF14259.1 EMC79035.1 - 1.1e-06 28.4 0.0 2.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 EMC79035.1 - 0.00054 19.7 0.1 0.00092 19.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC79035.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMC79035.1 - 0.0045 16.0 0.1 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMC79035.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase S_100 PF01023.14 EMC79036.1 - 0.13 11.5 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain zf-C2H2_4 PF13894.1 EMC79036.1 - 0.77 10.2 5.3 0.25 11.7 1.6 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger PID PF00640.18 EMC79037.1 - 6.8e-27 94.1 0.8 6.8e-27 94.1 0.6 2.2 2 1 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) CECR6_TMEM121 PF14997.1 EMC79038.1 - 4.5e-60 202.6 11.7 8e-60 201.7 8.1 1.4 1 0 0 1 1 1 1 CECR6/TMEM121 family EIID-AGA PF03613.9 EMC79038.1 - 0.0054 15.6 4.4 0.036 12.9 3.1 2.0 1 1 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component DUF996 PF06195.8 EMC79038.1 - 0.49 10.3 12.9 2.5 8.0 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) EBP PF05241.7 EMC79038.1 - 5.3 6.0 9.1 0.12 11.3 1.3 2.0 3 0 0 3 3 3 0 Emopamil binding protein DUF4509 PF14970.1 EMC79039.1 - 5.1e-60 202.3 0.1 5.7e-60 202.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) LIM PF00412.17 EMC79040.1 - 8.8e-14 51.3 2.0 9.5e-14 51.2 1.4 1.1 1 0 0 1 1 1 1 LIM domain Metallothio_Pro PF02069.11 EMC79040.1 - 0.011 15.5 0.7 0.013 15.3 0.5 1.2 1 0 0 1 1 1 0 Prokaryotic metallothionein TNFR_c6 PF00020.13 EMC79040.1 - 0.094 12.7 0.8 0.094 12.7 0.6 1.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region BAH PF01426.13 EMC79041.1 - 1.6e-31 108.5 1.8 3e-30 104.4 0.5 2.5 2 1 0 2 2 2 1 BAH domain ELM2 PF01448.19 EMC79041.1 - 2.6e-11 43.9 0.1 1.4e-10 41.6 0.0 2.3 2 0 0 2 2 2 1 ELM2 domain GATA PF00320.22 EMC79041.1 - 1.1e-08 34.2 11.0 2.3e-08 33.2 7.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.26 EMC79041.1 - 0.00096 19.1 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pacs-1 PF10254.4 EMC79042.1 - 1.5e-198 659.5 3.8 1.5e-198 659.5 2.6 1.6 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein Longin PF13774.1 EMC79043.1 - 3e-25 87.5 0.1 3.4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Regulated-SNARE-like domain Lectin_C PF00059.16 EMC79045.1 - 1.4e-15 57.7 4.4 1.7e-15 57.5 3.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 EMC79045.1 - 0.0088 15.4 0.9 0.016 14.6 0.6 1.7 1 1 0 1 1 1 1 UL45 protein ATG16 PF08614.6 EMC79047.1 - 2.7e-06 27.3 33.1 3.1e-05 23.9 9.4 7.6 3 2 5 8 8 8 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EMC79047.1 - 0.0029 16.8 26.9 0.0064 15.7 1.3 4.7 4 1 1 5 5 5 3 Reovirus sigma C capsid protein AMPKBI PF04739.10 EMC79048.1 - 4.3e-30 103.5 0.2 6.6e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain FMO-like PF00743.14 EMC79049.1 - 5.3e-253 840.0 0.0 6.5e-253 839.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMC79049.1 - 1.7e-18 67.4 0.0 7e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC79049.1 - 1.7e-10 40.3 0.3 7.7e-08 31.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC79049.1 - 1.6e-07 31.2 0.4 0.0013 18.5 0.1 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMC79049.1 - 7.1e-07 29.3 0.0 3e-05 23.9 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC79049.1 - 7.7e-06 25.8 0.1 0.00019 21.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC79049.1 - 0.00067 20.0 1.9 0.014 15.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC79049.1 - 0.0013 17.8 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EMC79049.1 - 0.0041 15.6 0.4 1.1 7.7 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 EMC79049.1 - 0.14 10.9 1.2 1.2 7.8 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EMC79049.1 - 0.21 11.7 0.2 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 EMC79049.1 - 0.22 11.0 0.3 8.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMC79049.1 - 0.25 11.0 0.5 7 6.3 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EMC79049.1 - 0.44 9.3 3.4 8.4 5.1 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.19 EMC79049.1 - 0.84 8.4 6.3 9.8 4.9 0.1 3.0 2 1 0 3 3 3 0 FAD dependent oxidoreductase ESPR PF13018.1 EMC79049.1 - 2.1 8.0 5.1 20 4.9 0.1 3.2 4 0 0 4 4 4 0 Extended Signal Peptide of Type V secretion system FMO-like PF00743.14 EMC79050.1 - 3.7e-259 860.3 0.0 4.1e-259 860.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMC79050.1 - 9.9e-18 64.9 0.0 2.7e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC79050.1 - 5.2e-11 42.8 0.0 1.2e-08 35.0 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC79050.1 - 3.2e-10 39.4 0.3 2.1e-07 30.1 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC79050.1 - 1e-06 28.6 1.0 0.00037 20.3 0.1 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMC79050.1 - 6.8e-06 26.0 0.0 2.3e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC79050.1 - 0.00012 21.2 0.1 0.066 12.2 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 EMC79050.1 - 0.012 16.0 0.9 0.31 11.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMC79050.1 - 0.041 13.6 0.6 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EMC79050.1 - 0.054 11.9 1.1 0.49 8.7 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein IlvN PF07991.7 EMC79050.1 - 0.074 12.4 0.1 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 EMC79050.1 - 0.16 11.4 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAO PF01266.19 EMC79050.1 - 0.21 10.4 2.4 1.7 7.4 0.2 2.6 1 1 1 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 EMC79050.1 - 0.57 8.9 1.7 7.1 5.3 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A PAP2 PF01569.16 EMC79051.1 - 1e-21 76.9 5.4 1.7e-21 76.2 3.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EMC79051.1 - 0.0011 19.1 3.8 0.0011 19.1 2.6 2.1 1 1 1 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 EMC79051.1 - 0.0042 16.6 5.5 0.0073 15.8 3.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily RFC1 PF08519.7 EMC79052.1 - 0.006 16.3 0.1 0.0082 15.9 0.1 1.2 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AhpC-TSA PF00578.16 EMC79053.1 - 1.6e-21 76.2 0.0 2.9e-21 75.4 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EMC79053.1 - 7.7e-14 51.0 0.4 1.7e-13 49.9 0.3 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EMC79053.1 - 8.4e-07 28.6 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin SAGA-Tad1 PF12767.2 EMC79054.1 - 5.4e-42 144.1 1.1 3.8e-40 138.1 0.8 2.2 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 EMC79054.1 - 0.034 13.4 0.0 0.075 12.2 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family TNF PF00229.13 EMC79055.1 - 0.00017 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.13 EMC79056.1 - 9.2e-33 112.5 0.2 1.2e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Sad1_UNC PF07738.8 EMC79057.1 - 3.9e-39 133.5 0.0 9.4e-39 132.3 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Trehalase PF01204.13 EMC79057.1 - 0.013 14.2 2.8 0.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Trehalase DUF4658 PF15555.1 EMC79057.1 - 0.017 15.0 0.3 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Tweety PF04906.8 EMC79057.1 - 0.029 12.7 3.7 0.049 12.0 2.6 1.2 1 0 0 1 1 1 0 Tweety Methyltransf_18 PF12847.2 EMC79058.1 - 4.5e-17 62.6 0.0 2.5e-07 31.2 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EMC79058.1 - 6.8e-17 61.7 0.1 1.6e-11 44.5 0.0 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EMC79058.1 - 4e-16 58.9 0.0 4.3e-11 42.6 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EMC79058.1 - 1.7e-08 34.7 0.0 3.5e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.12 EMC79058.1 - 2.1e-08 33.3 0.2 1.1e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EMC79058.1 - 1.3e-06 28.3 0.0 6e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC79058.1 - 1.5e-06 27.9 0.0 0.0012 18.6 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC79058.1 - 2.1e-05 24.9 0.0 0.01 16.3 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMC79058.1 - 0.00016 21.0 0.0 0.26 10.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Ham1p_like PF01725.11 EMC79059.1 - 2.5e-45 154.1 0.0 2.8e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Synaptobrevin PF00957.16 EMC79060.1 - 2.8e-35 119.7 2.5 3.8e-35 119.3 1.8 1.2 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.8 EMC79060.1 - 0.026 13.9 0.9 0.039 13.3 0.6 1.2 1 0 0 1 1 1 0 fzo-like conserved region NPV_P10 PF05531.7 EMC79060.1 - 0.04 14.1 0.2 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein L31 PF09784.4 EMC79060.1 - 0.072 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 RskA PF10099.4 EMC79060.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA UPF0258 PF06789.7 EMC79060.1 - 0.19 11.7 0.9 0.32 11.0 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Rifin_STEVOR PF02009.11 EMC79060.1 - 0.78 9.3 6.8 1.1 8.8 4.7 1.4 1 1 0 1 1 1 0 Rifin/stevor family OLF PF02191.11 EMC79061.1 - 1e-87 293.5 0.0 1.2e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain FMO-like PF00743.14 EMC79062.1 - 8.7e-238 789.8 0.0 9.7e-238 789.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMC79062.1 - 5.3e-18 65.8 0.0 1e-16 61.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC79062.1 - 4.2e-09 36.5 0.0 9.7e-07 28.8 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC79062.1 - 5.8e-08 32.0 0.0 4.4e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC79062.1 - 3.2e-06 27.0 0.0 2.4e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMC79062.1 - 1.1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC79062.1 - 0.0081 16.5 0.1 1.7 9.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EMC79062.1 - 0.21 10.7 0.0 0.66 9.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EMC79062.1 - 0.25 10.7 0.3 2.2 7.6 0.0 2.6 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA FMO-like PF00743.14 EMC79063.1 - 3.5e-114 381.8 0.0 4.1e-114 381.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FMO-like PF00743.14 EMC79064.1 - 5.5e-21 74.3 0.1 5.7e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMC79064.1 - 2.7e-07 30.5 0.0 2.8e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC79064.1 - 0.00011 21.4 0.0 0.00011 21.3 0.0 1.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMC79064.1 - 0.00068 18.5 0.0 0.00068 18.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC79064.1 - 0.0013 18.8 0.0 0.0013 18.7 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC79064.1 - 0.0027 17.6 0.0 0.0027 17.5 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC79064.1 - 0.0093 14.4 0.0 0.0097 14.4 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 EMC79064.1 - 0.039 13.6 0.0 0.041 13.5 0.0 1.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EMC79064.1 - 0.048 12.5 0.0 0.051 12.4 0.0 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC79064.1 - 0.061 13.7 0.0 0.064 13.6 0.0 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMC79064.1 - 0.075 12.3 0.0 0.075 12.3 0.0 1.0 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 EMC79064.1 - 0.095 11.7 0.1 0.097 11.7 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EMC79064.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EMC79064.1 - 0.14 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase Homeobox PF00046.24 EMC79065.1 - 3.7e-23 80.8 6.1 8.4e-23 79.7 4.3 1.6 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 EMC79065.1 - 4.6e-08 32.3 0.0 8.1e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 EMC79065.1 - 0.0025 17.4 0.1 0.006 16.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Transcrip_act PF04949.8 EMC79066.1 - 0.00021 20.9 17.8 0.00057 19.5 12.4 1.7 1 1 0 1 1 1 1 Transcriptional activator YscJ_FliF_C PF08345.6 EMC79066.1 - 0.34 10.8 5.1 0.13 12.2 1.4 1.8 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal DUF2407_C PF13373.1 EMC79066.1 - 0.72 9.7 0.0 0.72 9.7 0.0 2.7 3 0 0 3 3 3 0 DUF2407 C-terminal domain Ndc1_Nup PF09531.5 EMC79066.1 - 9.3 4.5 6.9 12 4.1 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_PK PF05891.7 EMC79067.1 - 1.2e-69 233.9 0.0 1.5e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EMC79067.1 - 0.00018 22.0 0.0 0.00029 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC79067.1 - 0.00034 21.0 0.0 0.00054 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMC79067.1 - 0.0011 18.1 0.1 0.0015 17.8 0.1 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EMC79067.1 - 0.0014 19.0 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain KAP PF05804.7 EMC79068.1 - 0 1280.1 27.1 0 1271.6 18.8 2.0 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.18 EMC79068.1 - 4.9e-06 26.1 10.9 0.067 13.0 0.0 7.3 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC79068.1 - 0.00014 22.0 0.0 2 8.7 0.0 4.8 3 2 1 4 4 4 2 HEAT repeats FPL PF09758.4 EMC79068.1 - 0.01 15.5 13.8 0.038 13.7 2.0 3.8 2 1 1 3 3 3 0 Uncharacterised conserved protein HEAT PF02985.17 EMC79068.1 - 0.13 12.4 1.7 11 6.3 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Pkinase PF00069.20 EMC79069.1 - 1.5e-06 27.5 0.4 2.2e-05 23.7 0.1 2.2 2 1 1 3 3 3 1 Protein kinase domain HEAT PF02985.17 EMC79069.1 - 0.044 13.8 1.6 14 6.1 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Pkinase_Tyr PF07714.12 EMC79069.1 - 0.078 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_M16 PF00675.15 EMC79071.1 - 1.3e-41 141.8 0.1 2.3e-40 137.7 0.0 2.9 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMC79071.1 - 1.7e-35 122.3 1.4 4.5e-20 72.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Nop14 PF04147.7 EMC79071.1 - 5.4 4.7 22.3 8.8 4.1 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.17 EMC79072.1 - 3.9e-61 205.1 0.5 4.6e-61 204.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC79072.1 - 7e-19 68.4 0.0 9.9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC79072.1 - 4.3e-13 48.8 0.2 5.2e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC79072.1 - 1.6e-05 24.1 0.0 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMC79072.1 - 3.3e-05 23.1 0.0 0.00013 21.2 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMC79072.1 - 0.00014 21.3 0.1 0.00035 20.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMC79072.1 - 0.0076 15.5 0.0 3.5 6.8 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EMC79072.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EMC79072.1 - 0.012 14.2 0.1 2.3 6.8 0.0 3.0 2 1 1 3 3 3 0 G-protein alpha subunit DUF258 PF03193.11 EMC79072.1 - 0.047 12.8 0.0 8.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMC79072.1 - 0.13 12.1 0.1 0.34 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Thioredoxin_7 PF13899.1 EMC79073.1 - 1e-17 63.9 0.0 1.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 EMC79073.1 - 8.7e-08 31.7 0.0 1.3e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMC79073.1 - 1.4e-05 25.2 0.1 9.3e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 EMC79073.1 - 0.00054 19.7 0.1 0.00069 19.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.1 EMC79073.1 - 0.00068 19.7 0.0 0.0023 17.9 0.0 1.8 1 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EMC79073.1 - 0.00078 19.0 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EMC79073.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.19 EMC79073.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin NAC PF01849.13 EMC79074.1 - 1e-22 79.3 0.1 1.7e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain DUF3480 PF11979.3 EMC79075.1 - 8.7e-172 570.6 0.0 1.2e-171 570.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) SARA PF11409.3 EMC79075.1 - 8.8e-22 76.7 11.8 8.8e-22 76.7 8.2 2.2 2 0 0 2 2 2 1 Smad anchor for receptor activation (SARA) FYVE PF01363.16 EMC79075.1 - 1.4e-19 69.7 16.0 1.4e-19 69.7 11.1 2.4 2 0 0 2 2 2 1 FYVE zinc finger C2 PF00168.25 EMC79076.1 - 3.6e-05 23.5 0.0 0.00014 21.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain PRP38 PF03371.10 EMC79077.1 - 6e-68 227.8 1.2 7.5e-68 227.5 0.9 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 EMC79077.1 - 0.002 18.6 52.9 0.002 18.6 36.7 2.2 1 1 1 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PAP_assoc PF03828.14 EMC79078.1 - 4.3e-31 106.6 0.8 4.5e-16 58.5 0.1 2.9 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.18 EMC79078.1 - 2.1e-12 46.3 22.1 3.3e-05 23.5 0.8 3.8 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.18 EMC79078.1 - 6.8e-11 42.3 0.0 1.2e-06 28.6 0.0 2.7 2 0 0 2 2 2 2 Nucleotidyltransferase domain zf-CCHC_2 PF13696.1 EMC79078.1 - 1.4e-05 24.4 21.2 0.0066 15.9 0.7 4.7 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 EMC79078.1 - 1.5e-05 24.5 18.1 0.058 13.0 0.6 3.7 3 0 0 3 3 3 3 Zinc knuckle Ubiq_cyt_C_chap PF03981.7 EMC79078.1 - 0.086 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Shisa PF13908.1 EMC79079.1 - 6.9e-05 23.1 5.7 6.9e-05 23.1 4.0 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator PDR_assoc PF08370.6 EMC79079.1 - 0.0051 16.2 0.8 0.0083 15.6 0.6 1.4 1 0 0 1 1 1 1 Plant PDR ABC transporter associated EpsG PF14897.1 EMC79079.1 - 0.0064 15.4 0.1 0.0076 15.2 0.0 1.0 1 0 0 1 1 1 1 EpsG family Adeno_E3_CR2 PF02439.10 EMC79079.1 - 0.038 13.5 1.5 0.07 12.6 1.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Metallothio_Cad PF07846.6 EMC79079.1 - 0.1 12.4 2.7 0.24 11.3 1.9 1.6 1 0 0 1 1 1 0 Metallothionein family Sel1 PF08238.7 EMC79080.1 - 3.9e-17 62.2 0.0 7.8e-05 23.1 0.0 4.2 4 0 0 4 4 4 4 Sel1 repeat DUF4315 PF14193.1 EMC79080.1 - 0.017 15.0 1.1 0.03 14.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) LRR_4 PF12799.2 EMC79081.1 - 0.0019 17.7 8.0 0.0031 17.0 0.2 4.2 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC79081.1 - 0.0021 17.9 4.8 0.69 10.1 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat His_kinase PF06580.8 EMC79081.1 - 0.0094 15.8 0.5 0.033 14.1 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase LRR_8 PF13855.1 EMC79081.1 - 0.011 15.5 7.3 0.042 13.6 1.2 3.9 2 1 1 3 3 3 0 Leucine rich repeat RIX1 PF08167.7 EMC79081.1 - 0.045 13.4 7.6 0.4 10.3 0.2 3.6 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis LRR_1 PF00560.28 EMC79081.1 - 0.21 11.7 3.0 13 6.3 0.0 4.5 3 1 1 4 4 4 0 Leucine Rich Repeat ECH PF00378.15 EMC79082.1 - 2.3e-53 180.8 1.1 2.6e-53 180.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EMC79082.1 - 0.16 11.7 0.3 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 LRR_8 PF13855.1 EMC79083.1 - 1.2e-75 249.1 54.3 1e-15 57.1 2.4 8.1 7 1 0 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 EMC79083.1 - 2.2e-51 170.7 67.0 3.1e-07 29.8 1.6 11.9 6 3 7 13 13 13 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC79083.1 - 1.2e-42 137.3 47.9 0.0018 18.0 0.3 18.2 18 2 1 19 19 19 13 Leucine Rich Repeat LRR_5 PF13306.1 EMC79083.1 - 6e-23 80.9 3.6 1e-06 28.4 0.0 5.1 2 1 5 7 7 7 7 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC79083.1 - 8.1e-21 70.4 49.1 0.34 11.2 0.2 16.1 17 0 0 17 17 17 8 Leucine rich repeat LRR_6 PF13516.1 EMC79083.1 - 4.3e-16 57.1 65.0 0.069 13.2 0.1 15.4 17 1 1 18 18 18 9 Leucine Rich repeat LRR_9 PF14580.1 EMC79083.1 - 1.1e-09 38.1 17.8 0.08 12.4 0.1 6.6 1 1 6 7 7 7 6 Leucine-rich repeat FNIP PF05725.7 EMC79083.1 - 0.018 14.9 21.7 5.6 6.9 0.2 7.7 5 2 2 7 7 7 0 FNIP Repeat LRRNT PF01462.13 EMC79083.1 - 1.4 8.5 4.3 29 4.3 0.0 3.8 5 0 0 5 5 5 0 Leucine rich repeat N-terminal domain SDF PF00375.13 EMC79084.1 - 2.7e-128 428.0 28.1 3.1e-128 427.8 19.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FeoB_C PF07664.7 EMC79084.1 - 0.63 9.5 7.4 3.5 7.1 0.5 4.5 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus Carn_acyltransf PF00755.15 EMC79085.1 - 3.4e-186 619.8 0.0 3.9e-186 619.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF866 PF05907.8 EMC79086.1 - 3e-52 176.3 0.2 3.3e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Mago_nashi PF02792.9 EMC79087.1 - 1e-62 210.0 0.1 1.1e-62 209.9 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Ldl_recept_a PF00057.13 EMC79088.1 - 1.9e-76 251.6 138.3 2.6e-14 52.8 6.8 7.9 8 0 0 8 8 7 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 EMC79088.1 - 7.6e-63 208.5 8.5 3.1e-15 56.2 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 EMC79088.1 - 4.1e-16 58.7 36.8 2.5e-09 37.1 5.6 6.0 5 1 0 5 5 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC79088.1 - 3.7e-09 36.0 15.9 3.5e-06 26.5 0.5 6.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like SGL PF08450.7 EMC79088.1 - 4.4e-07 29.5 0.7 0.0058 16.0 0.0 2.6 1 1 2 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region EGF_CA PF07645.10 EMC79088.1 - 3e-06 27.1 11.3 3e-06 27.1 7.8 10.2 6 2 3 9 9 7 2 Calcium-binding EGF domain EGF PF00008.22 EMC79088.1 - 0.00012 21.9 20.3 0.00015 21.6 3.5 9.2 9 1 1 10 10 10 3 EGF-like domain NHL PF01436.16 EMC79088.1 - 0.00063 19.5 1.0 2.2 8.4 0.0 5.6 7 0 0 7 7 7 1 NHL repeat SKG6 PF08693.5 EMC79088.1 - 0.0031 16.7 0.1 0.007 15.6 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 EMC79088.1 - 0.0076 15.9 0.9 0.018 14.7 0.7 1.6 1 1 0 1 1 1 1 TMEM154 protein family Arylesterase PF01731.15 EMC79088.1 - 0.023 14.6 0.0 3.4 7.6 0.0 3.3 3 0 0 3 3 3 0 Arylesterase DUF2207 PF09972.4 EMC79088.1 - 0.14 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DM PF00751.13 EMC79089.1 - 3.4e-20 71.3 8.0 4.9e-20 70.7 5.6 1.3 1 0 0 1 1 1 1 DM DNA binding domain zf-H2C2_2 PF13465.1 EMC79090.1 - 7e-15 54.4 20.2 5.8e-06 26.3 0.5 5.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79090.1 - 3.2e-14 52.2 31.9 0.0018 18.5 0.6 6.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79090.1 - 1.2e-10 40.9 25.5 0.0028 17.8 0.1 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger DUF3558 PF12079.3 EMC79090.1 - 0.039 13.6 0.6 0.12 11.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) zf-met PF12874.2 EMC79090.1 - 0.21 11.8 6.2 1.6 9.0 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC79090.1 - 0.56 10.4 7.3 26 5.0 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.6 EMC79090.1 - 1.6 8.4 5.3 12 5.7 0.0 4.4 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger Yip1 PF04893.12 EMC79091.1 - 4.9e-20 71.7 11.4 7e-20 71.2 7.9 1.3 1 0 0 1 1 1 1 Yip1 domain ELF PF03317.8 EMC79091.1 - 0.063 12.5 1.3 0.091 12.0 0.9 1.2 1 0 0 1 1 1 0 ELF protein T4_deiodinase PF00837.12 EMC79092.1 - 7.3e-22 77.5 0.0 8.6e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Ldl_recept_a PF00057.13 EMC79094.1 - 2.8e-13 49.5 27.9 6.9e-06 25.8 4.1 3.4 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A BSMAP PF12280.3 EMC79095.1 - 2e-74 249.9 1.1 2e-74 249.9 0.8 2.2 1 1 1 2 2 2 2 Brain specific membrane anchored protein Med26 PF08711.6 EMC79096.1 - 9.1e-16 57.1 0.3 9.1e-16 57.1 0.2 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_M PF07500.9 EMC79096.1 - 4.5e-08 33.1 0.3 4.8e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Lipase_GDSL_3 PF14606.1 EMC79096.1 - 0.13 11.9 0.1 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CUB PF00431.15 EMC79098.1 - 8e-94 309.1 0.0 6e-32 109.9 0.0 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.15 EMC79098.1 - 0.00017 21.0 0.1 0.075 12.5 0.0 3.3 3 0 0 3 3 3 1 CUB-like domain NAD_binding_1 PF00175.16 EMC79099.1 - 8.2e-13 48.8 0.0 5.6e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMC79099.1 - 3e-12 46.5 0.0 5.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Oxidored-like PF09791.4 EMC79099.1 - 1.4e-11 43.6 1.4 2.2e-10 39.8 1.5 2.2 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.7 EMC79099.1 - 0.00015 21.6 0.2 0.014 15.3 0.0 2.8 2 1 0 3 3 3 1 Ferric reductase NAD binding domain TrbC_Ftype PF09673.5 EMC79099.1 - 0.004 16.7 0.0 0.5 9.9 0.0 2.4 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein PDCD9 PF07147.7 EMC79100.1 - 6e-25 87.9 0.0 1.2e-24 86.9 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Thi4 PF01946.12 EMC79100.1 - 0.049 12.7 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Thi4 family SSDP PF04503.8 EMC79101.1 - 1.5e-117 392.5 68.0 1.7e-117 392.4 47.1 1.0 1 0 0 1 1 1 1 Single-stranded DNA binding protein, SSDP START PF01852.14 EMC79102.1 - 2.1e-27 95.7 0.1 3.4e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 START domain 4HBT PF03061.17 EMC79102.1 - 1.2e-21 76.5 0.1 2.3e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF2693 PF10902.3 EMC79102.1 - 0.16 11.9 0.4 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) TPR_11 PF13414.1 EMC79103.1 - 3.7e-17 61.7 0.9 1.6e-12 46.9 0.8 2.3 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMC79103.1 - 9.4e-16 56.6 2.4 0.00029 20.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC79103.1 - 3.8e-13 48.2 1.2 0.0064 16.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC79103.1 - 4.5e-06 26.0 1.4 0.33 10.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC79103.1 - 2.3e-05 24.2 0.4 0.00036 20.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC79103.1 - 3.2e-05 24.4 0.0 0.015 15.9 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC79103.1 - 0.0058 17.1 0.0 0.75 10.6 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC79103.1 - 0.014 15.5 0.4 0.054 13.6 0.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMC79103.1 - 0.014 15.7 0.0 0.032 14.5 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMC79103.1 - 0.031 14.1 0.0 2.1 8.2 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.20 EMC79104.1 - 2.9e-39 134.3 0.0 4e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC79104.1 - 3.2e-06 27.0 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 EMC79104.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase tRNA-synt_2 PF00152.15 EMC79104.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) FAD_binding_4 PF01565.18 EMC79105.1 - 8.5e-18 64.1 0.1 1.4e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TMEM61 PF15105.1 EMC79106.1 - 2e-43 148.2 1.2 2.3e-43 148.0 0.8 1.0 1 0 0 1 1 1 1 TMEM61 protein family DUF4131 PF13567.1 EMC79106.1 - 0.044 13.1 1.2 0.055 12.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ribophorin_II PF05817.9 EMC79106.1 - 0.21 9.7 0.1 0.27 9.3 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Barttin PF15462.1 EMC79107.1 - 1.7e-32 112.8 11.8 3.2e-31 108.7 5.9 2.7 1 1 1 2 2 2 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Peptidase_S8 PF00082.17 EMC79108.1 - 1.4e-33 116.2 0.6 1.9e-33 115.8 0.4 1.1 1 0 0 1 1 1 1 Subtilase family UCH PF00443.24 EMC79109.1 - 4.2e-54 183.4 0.2 1.1e-53 182.0 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC79109.1 - 4.5e-26 91.9 0.0 9.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PAP2 PF01569.16 EMC79110.1 - 5.1e-21 74.7 1.7 5.1e-21 74.7 1.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EMC79110.1 - 1.2e-05 25.5 3.0 1.2e-05 25.5 2.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily C-terminal YhhN PF07947.9 EMC79110.1 - 0.084 12.2 4.9 0.25 10.6 3.4 1.7 1 1 0 1 1 1 0 YhhN-like protein FSH1 PF03959.8 EMC79110.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) hSH3 PF14603.1 EMC79111.1 - 4e-13 49.1 0.1 1.1e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Helically-extended SH3 domain MACPF PF01823.14 EMC79112.1 - 6.3e-48 163.2 0.5 1.3e-46 159.0 0.0 2.1 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.13 EMC79112.1 - 2.8e-10 39.9 11.7 2.8e-10 39.9 8.1 2.8 1 1 1 2 2 2 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 EMC79112.1 - 0.00045 20.2 36.8 0.0018 18.3 8.3 3.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain hEGF PF12661.2 EMC79112.1 - 6.9 6.9 16.4 0.69 10.1 3.4 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF MACPF PF01823.14 EMC79113.1 - 4.3e-44 150.7 0.5 8.3e-44 149.8 0.0 1.6 1 1 1 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.13 EMC79113.1 - 4.4e-08 32.8 11.4 1.6e-07 31.0 7.9 2.1 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 EMC79113.1 - 1.3e-06 28.4 34.0 5.5e-05 23.1 7.0 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain PID PF00640.18 EMC79114.1 - 5.7e-24 84.6 0.1 9.3e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Peptidase_M48 PF01435.13 EMC79115.1 - 2.7e-32 112.1 0.1 3.8e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 EMC79115.1 - 0.062 12.4 0.3 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SWIRM PF04433.12 EMC79116.1 - 5.6e-20 71.2 0.0 1.6e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain JAB PF01398.16 EMC79116.1 - 2.3e-13 49.9 0.0 5.7e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.26 EMC79116.1 - 3.9e-12 46.0 0.1 1.1e-11 44.6 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-JAB PF14464.1 EMC79116.1 - 1.4e-09 37.4 0.0 3.8e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.1 EMC79116.1 - 1.1e-05 25.4 0.6 3.6e-05 23.7 0.4 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0172 PF03665.8 EMC79116.1 - 0.0046 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Ank_2 PF12796.2 EMC79117.1 - 1.2e-115 378.1 40.0 4.5e-25 87.8 0.2 7.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMC79117.1 - 1.9e-105 339.7 33.0 2.8e-09 36.3 0.1 14.8 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.1 EMC79117.1 - 2.3e-76 244.0 25.9 2.6e-06 27.1 0.0 15.0 14 1 1 15 15 15 14 Ankyrin repeat Ank_5 PF13857.1 EMC79117.1 - 6.5e-76 248.6 21.4 5.8e-13 48.6 0.0 11.8 2 2 9 12 12 12 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC79117.1 - 1.4e-75 248.4 32.3 3.8e-10 39.9 0.1 11.3 4 3 9 13 13 13 12 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EMC79117.1 - 0.095 12.1 2.7 58 3.0 0.0 4.2 4 0 0 4 4 4 0 Shigella flexneri OspC protein DUF3447 PF11929.3 EMC79117.1 - 0.11 12.3 0.0 5.9 6.7 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) FGGY_C PF02782.11 EMC79118.1 - 1.3e-46 158.7 0.1 2e-46 158.1 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMC79118.1 - 8.2e-29 100.6 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EMC79118.1 - 0.007 15.6 0.0 0.15 11.3 0.0 2.6 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family zf-RING_2 PF13639.1 EMC79119.1 - 5.5e-10 38.9 9.1 9.3e-10 38.1 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC79119.1 - 7.4e-10 38.3 7.7 1.5e-09 37.3 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC79119.1 - 3e-09 36.3 4.3 5.3e-09 35.5 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC79119.1 - 4.7e-09 35.9 8.6 1.1e-08 34.7 5.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMC79119.1 - 4.9e-09 36.0 8.7 9.6e-09 35.1 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC79119.1 - 5.9e-06 25.9 1.5 5.9e-06 25.9 1.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC79119.1 - 8.6e-06 25.3 10.1 3e-05 23.6 6.1 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC79119.1 - 0.008 15.9 6.7 0.061 13.1 4.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-B_box PF00643.19 EMC79119.1 - 0.035 13.9 7.2 1.2 9.0 0.3 3.3 3 0 0 3 3 3 0 B-box zinc finger zf-rbx1 PF12678.2 EMC79119.1 - 0.07 13.2 9.7 0.17 11.9 6.7 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 EMC79119.1 - 0.16 11.8 7.1 0.32 10.9 4.8 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain zf-Nse PF11789.3 EMC79119.1 - 0.19 11.2 6.6 0.35 10.4 4.3 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EMC79119.1 - 0.26 10.9 9.3 4 7.1 5.9 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EMC79119.1 - 0.34 10.6 9.9 0.61 9.8 6.7 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Sec23_Sec24 PF04810.10 EMC79119.1 - 1.5 8.4 11.7 1.4 8.5 0.6 3.0 2 2 1 3 3 3 0 Sec23/Sec24 zinc finger zf-Di19 PF05605.7 EMC79119.1 - 3.4 7.8 8.0 77 3.5 5.3 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-MIZ PF02891.15 EMC79119.1 - 4.2 6.9 15.1 0.84 9.1 7.5 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EMC79119.1 - 5.1 6.9 8.9 27 4.6 6.2 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-met2 PF12907.2 EMC79119.1 - 5.9 6.9 8.6 15 5.6 0.5 3.0 3 0 0 3 3 3 0 Zinc-binding DZR PF12773.2 EMC79119.1 - 8.5 6.2 9.4 1.5e+02 2.3 5.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon HOOK PF05622.7 EMC79120.1 - 0 1106.6 76.6 0 1106.4 53.1 1.0 1 0 0 1 1 1 1 HOOK protein ATG16 PF08614.6 EMC79120.1 - 4.5e-09 36.4 88.0 0.00018 21.4 13.6 5.9 1 1 4 5 5 5 4 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EMC79120.1 - 0.00026 19.7 14.1 0.00026 19.7 9.8 4.9 1 1 4 5 5 5 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EMC79120.1 - 0.00084 18.6 19.5 0.0073 15.5 0.3 3.5 3 0 0 3 3 3 3 Reovirus sigma C capsid protein DUF869 PF05911.6 EMC79120.1 - 1.8 6.6 81.0 0.032 12.4 17.8 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) Vip3A_N PF12495.3 EMC79120.1 - 7.8 6.1 15.1 0.92 9.1 2.1 3.4 2 1 1 3 3 3 0 Vegetative insecticide protein 3A N terminal p450 PF00067.17 EMC79121.1 - 3.8e-135 450.9 0.1 4.4e-135 450.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC79122.1 - 1.2e-132 442.6 0.4 1.4e-132 442.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC79123.1 - 1.2e-130 436.1 0.1 1.4e-130 435.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC79124.1 - 6.6e-14 51.2 0.0 7.5e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC79126.1 - 4e-42 144.3 0.1 4.4e-42 144.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC79127.1 - 2.1e-10 39.7 0.6 2.2e-10 39.6 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Clathrin PF00637.15 EMC79128.1 - 0.0092 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Region in Clathrin and VPS TM2 PF05154.11 EMC79132.1 - 9.1e-18 64.2 5.6 1.3e-17 63.6 3.9 1.2 1 0 0 1 1 1 1 TM2 domain PDZ PF00595.19 EMC79133.1 - 1.1e-17 63.9 0.0 2e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC79133.1 - 9.3e-07 28.6 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Ank_2 PF12796.2 EMC79134.1 - 2.6e-25 88.5 5.7 1e-16 61.0 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC79134.1 - 1.7e-22 78.9 5.4 2.9e-13 49.5 0.2 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EMC79134.1 - 5.4e-22 76.4 5.5 5.9e-06 25.8 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EMC79134.1 - 3.1e-20 72.1 3.9 1.1e-08 35.3 0.0 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC79134.1 - 1.5e-17 61.8 0.3 0.00046 20.1 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat PhaP_Bmeg PF09602.5 EMC79134.1 - 0.018 14.8 0.3 0.03 14.1 0.2 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) UCH PF00443.24 EMC79136.1 - 6.4e-37 127.1 8.8 6.8e-30 104.0 4.3 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC79136.1 - 1e-16 61.2 0.0 2.5e-11 43.5 0.0 3.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Fibrinogen_C PF00147.13 EMC79137.1 - 6.8e-52 176.3 0.8 1.5e-51 175.3 0.6 1.6 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Reo_sigmaC PF04582.7 EMC79137.1 - 0.015 14.4 1.0 0.022 13.9 0.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein YscJ_FliF_C PF08345.6 EMC79137.1 - 0.16 11.9 1.6 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal NCKAP5 PF15246.1 EMC79137.1 - 0.7 9.2 7.6 1 8.6 5.3 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein RTBV_P46 PF06216.6 EMC79137.1 - 1.6 7.4 8.6 0.25 10.1 1.5 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Peptidase_C54 PF03416.14 EMC79138.1 - 3.5e-113 377.3 0.0 1.3e-112 375.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C54 Alg6_Alg8 PF03155.10 EMC79139.1 - 4.3e-149 497.3 29.2 5.2e-149 497.0 20.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family CENP-R PF06729.7 EMC79140.1 - 3.1e-61 205.1 4.8 3.6e-61 204.8 3.3 1.0 1 0 0 1 1 1 1 Kinetochore component, CENP-R EF-hand_7 PF13499.1 EMC79141.1 - 1.4e-16 60.3 0.8 1.7e-08 34.4 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC79141.1 - 2.2e-14 51.5 1.5 0.0019 17.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EMC79141.1 - 4.3e-10 39.0 5.2 8.6e-07 28.4 0.0 4.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC79141.1 - 1.3e-07 30.9 3.3 0.00085 19.0 0.1 3.7 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EMC79141.1 - 3.4e-06 26.1 1.0 0.11 11.8 0.2 3.4 3 0 0 3 3 3 2 EF hand EF_assoc_2 PF08356.7 EMC79141.1 - 0.019 14.6 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 EF hand associated EFhand_Ca_insen PF08726.5 EMC79141.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 EMC79141.1 - 0.029 14.1 0.4 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EMC79141.1 - 0.065 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) PGM_PMM_I PF02878.11 EMC79142.1 - 3.8e-34 117.1 0.1 6.3e-34 116.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EMC79142.1 - 9.4e-31 106.1 0.0 1.7e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EMC79142.1 - 4.4e-18 65.5 0.0 1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMC79142.1 - 4.5e-10 39.3 0.0 1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain VWA_N PF08399.6 EMC79143.1 - 5.6e-30 104.4 0.1 4.2e-29 101.6 0.0 2.4 2 0 0 2 2 2 1 VWA N-terminal Cache_1 PF02743.13 EMC79143.1 - 1.3e-16 59.9 0.1 6.1e-10 38.5 0.0 3.0 2 1 0 2 2 2 2 Cache domain VWA PF00092.23 EMC79143.1 - 1.2e-06 28.4 1.5 2.2e-06 27.5 1.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC79143.1 - 0.024 14.3 0.1 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain RRM_1 PF00076.17 EMC79144.1 - 1e-26 92.3 3.6 6.3e-14 51.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79144.1 - 2.6e-19 68.7 1.0 1.2e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79144.1 - 3.2e-19 68.6 0.1 1.8e-07 31.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC79144.1 - 0.13 12.0 0.0 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 ADK PF00406.17 EMC79145.1 - 1.1e-28 99.9 0.0 1.3e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMC79145.1 - 2.4e-16 59.0 0.0 5.3e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EMC79145.1 - 0.026 14.8 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PTEN_C2 PF10409.4 EMC79146.1 - 1.1e-25 89.9 0.0 2.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.26 EMC79146.1 - 5.1e-07 29.3 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase PF00102.22 EMC79146.1 - 0.00091 18.6 0.1 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Vps55 PF04133.9 EMC79147.1 - 4.1e-39 133.0 4.4 4.6e-39 132.8 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 YwiC PF14256.1 EMC79147.1 - 0.94 9.5 5.7 1.4 9.0 3.5 1.5 1 1 0 1 1 1 0 YwiC-like protein MtN3_slv PF03083.11 EMC79147.1 - 6 6.8 6.9 2.5 8.0 0.4 2.5 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange Lep_receptor_Ig PF06328.6 EMC79148.1 - 2.8e-30 104.0 0.8 1.2e-29 101.9 0.6 2.2 1 0 0 1 1 1 1 Ig-like C2-type domain fn3 PF00041.16 EMC79148.1 - 9.1e-09 35.3 10.0 0.0088 16.1 0.0 5.1 5 0 0 5 5 5 3 Fibronectin type III domain PDEase_I PF00233.14 EMC79150.1 - 1.4e-106 355.5 6.9 1.4e-106 355.5 4.8 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DFP PF04127.10 EMC79150.1 - 0.14 11.7 2.5 0.088 12.4 0.2 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Tctex-1 PF03645.8 EMC79151.1 - 1.5e-25 88.9 0.0 1.7e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF1903 PF08991.5 EMC79151.1 - 0.066 13.3 0.1 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Insulin PF00049.13 EMC79152.1 - 1.6e-07 31.9 2.7 6.8e-07 29.9 1.9 1.8 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.9 EMC79152.1 - 0.0022 17.7 7.1 0.35 10.7 0.1 2.3 2 0 0 2 2 2 2 Nematode insulin-related peptide beta type WD40 PF00400.27 EMC79153.1 - 8.3e-14 50.8 9.7 6.4e-08 32.1 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3312 PF11768.3 EMC79153.1 - 0.0056 14.9 0.1 0.009 14.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) DUF1830 PF08865.6 EMC79153.1 - 0.07 12.7 0.0 0.25 10.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) ELM2 PF01448.19 EMC79154.1 - 1.5e-12 47.9 2.0 2.2e-12 47.4 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 EMC79154.1 - 0.00012 22.0 0.1 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPT PF03151.11 EMC79155.1 - 1.4e-12 47.5 8.5 1.4e-12 47.5 5.9 1.9 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMC79155.1 - 0.00037 19.5 14.2 0.00057 18.8 9.8 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMC79155.1 - 0.0046 17.0 16.3 0.2 11.7 1.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family PglZ PF08665.7 EMC79155.1 - 0.074 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PglZ domain IL6Ra-bind PF09240.5 EMC79157.1 - 0.021 14.9 0.9 0.039 14.1 0.0 1.7 1 1 1 2 2 2 0 Interleukin-6 receptor alpha chain, binding HABP4_PAI-RBP1 PF04774.10 EMC79158.1 - 2e-36 124.6 11.3 2e-36 124.6 7.8 1.9 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family Ribosomal_L7Ae PF01248.21 EMC79159.1 - 7.8e-16 57.3 0.0 1.1e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Caenor_Her-1 PF09232.5 EMC79159.1 - 0.055 13.5 0.1 0.082 12.9 0.1 1.3 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 G-gamma PF00631.17 EMC79160.1 - 1.5e-17 63.1 0.0 1.6e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain Ras PF00071.17 EMC79161.1 - 2.1e-46 157.2 0.1 2.5e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC79161.1 - 6.4e-24 84.7 0.4 1.3e-23 83.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC79161.1 - 4.6e-07 29.2 0.0 7.1e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC79161.1 - 0.00025 20.5 0.1 0.00069 19.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMC79161.1 - 0.00085 18.1 0.2 0.18 10.5 0.1 2.2 2 0 0 2 2 2 2 ArgK protein FeoB_N PF02421.13 EMC79161.1 - 0.0012 18.1 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EMC79161.1 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC79161.1 - 0.002 17.3 1.1 0.0078 15.4 0.7 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMC79161.1 - 0.0029 17.7 0.0 0.012 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMC79161.1 - 0.023 13.9 0.6 0.06 12.5 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EMC79161.1 - 0.032 13.8 1.4 0.041 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EMC79161.1 - 0.034 12.7 0.8 0.3 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain FGF PF00167.13 EMC79161.1 - 0.037 13.7 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Fibroblast growth factor Arch_ATPase PF01637.13 EMC79161.1 - 0.058 13.0 0.1 0.088 12.4 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EMC79161.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC79161.1 - 0.092 12.3 0.0 0.51 9.9 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EMC79161.1 - 0.1 12.5 0.4 0.17 11.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF2408 PF10303.4 EMC79161.1 - 0.5 10.4 3.8 1.7 8.7 2.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) MIG-14_Wnt-bd PF06664.7 EMC79162.1 - 6.1e-92 307.6 17.9 7.6e-92 307.3 12.4 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion RPE65 PF03055.10 EMC79163.1 - 2.1e-122 409.1 0.1 2.4e-122 408.9 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DEP PF00610.16 EMC79164.1 - 1.7e-17 62.8 0.0 5.6e-17 61.2 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 EMC79164.1 - 1.7e-05 24.4 2.4 0.18 11.3 0.1 3.3 3 0 0 3 3 3 2 RhoGAP domain LRR_4 PF12799.2 EMC79165.1 - 3.2e-64 211.7 72.1 4.3e-10 38.9 2.0 11.3 4 3 9 14 14 14 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79165.1 - 1.4e-50 168.8 65.6 2.5e-12 46.3 3.6 8.7 4 2 3 10 10 10 8 Leucine rich repeat LRR_1 PF00560.28 EMC79165.1 - 2.5e-39 127.2 59.7 0.00031 20.3 0.4 18.8 19 0 0 19 19 19 12 Leucine Rich Repeat LRR_7 PF13504.1 EMC79165.1 - 1.3e-24 81.8 58.7 0.0082 16.1 0.2 16.8 17 0 0 17 17 17 9 Leucine rich repeat LRR_6 PF13516.1 EMC79165.1 - 3.1e-10 39.0 61.5 0.025 14.6 0.1 17.1 16 3 3 19 19 19 5 Leucine Rich repeat LRR_9 PF14580.1 EMC79165.1 - 8e-05 22.2 21.9 0.029 13.9 0.4 5.4 2 2 4 6 6 6 3 Leucine-rich repeat Dynactin_p22 PF07426.6 EMC79165.1 - 0.17 11.1 9.8 0.18 11.0 0.3 3.9 2 1 0 4 4 4 0 Dynactin subunit p22 Stk19 PF10494.4 EMC79165.1 - 0.47 9.7 6.3 1.1 8.5 0.1 3.0 3 1 0 3 3 3 0 Serine-threonine protein kinase 19 RRM_5 PF13893.1 EMC79166.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC79166.1 - 0.17 11.5 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 PF01254.13 EMC79166.1 - 4.3 7.6 57.9 4.2 7.7 26.4 2.3 1 1 1 2 2 2 0 Nuclear transition protein 2 DUF936 PF06075.7 EMC79166.1 - 6.1 5.6 34.8 7.4 5.3 24.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Band_3_cyto PF07565.8 EMC79166.1 - 7.7 5.9 10.4 11 5.4 7.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GPCR_chapero_1 PF11904.3 EMC79167.1 - 5.3e-72 242.5 0.2 7.5e-72 242.0 0.1 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 EMC79167.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC79167.1 - 0.028 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.25 EMC79167.1 - 0.035 13.9 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Cys_Met_Meta_PP PF01053.15 EMC79168.1 - 7.1e-148 492.0 0.0 7.9e-148 491.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMC79168.1 - 1.1e-06 27.9 0.1 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EMC79168.1 - 3.6e-06 26.1 0.1 5.2e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMC79168.1 - 5e-06 25.5 0.2 7.5e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 EMC79168.1 - 0.0015 17.3 0.1 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein 7tm_1 PF00001.16 EMC79169.1 - 1.2e-15 57.3 11.4 1.6e-15 56.9 7.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 EMC79169.1 - 1.5e-07 30.9 6.0 1.5e-07 30.9 4.1 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.4 EMC79169.1 - 0.00084 18.5 12.0 0.0011 18.1 8.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Oxidored_q2 PF00420.19 EMC79169.1 - 0.0066 16.0 0.2 0.0066 16.0 0.1 3.4 2 2 2 4 4 4 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L US22 PF02393.11 EMC79169.1 - 0.015 15.3 0.5 2.5 8.1 0.0 2.9 1 1 2 3 3 3 0 US22 like DUF4149 PF13664.1 EMC79169.1 - 0.046 13.7 0.8 0.046 13.7 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) zf-RanBP PF00641.13 EMC79170.1 - 7.2e-10 37.7 19.6 8.5e-07 27.9 6.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EMC79170.1 - 0.55 10.0 9.8 7 6.5 1.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Nop14 PF04147.7 EMC79170.1 - 0.81 7.5 25.4 0.99 7.2 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family GCC2_GCC3 PF07699.8 EMC79170.1 - 2.8 7.5 8.5 1.2 8.7 0.1 3.2 2 1 0 2 2 2 0 GCC2 and GCC3 Ebola_NP PF05505.7 EMC79170.1 - 3.1 5.7 14.5 3.8 5.4 10.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Macoilin PF09726.4 EMC79170.1 - 5 5.2 23.3 5.7 5.0 16.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Transformer PF06495.6 EMC79170.1 - 6.3 6.6 35.7 0.51 10.1 21.6 1.5 2 0 0 2 2 2 0 Fruit fly transformer protein Daxx PF03344.10 EMC79170.1 - 6.8 5.0 28.3 8.7 4.6 19.6 1.1 1 0 0 1 1 1 0 Daxx Family I-set PF07679.11 EMC79171.1 - 4.7e-34 116.1 0.2 6e-12 45.2 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC79171.1 - 1.2e-27 95.8 0.3 3.5e-11 43.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC79171.1 - 1e-26 93.1 2.0 1.5e-11 44.6 0.0 3.9 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 EMC79171.1 - 3.5e-18 65.4 2.2 3.3e-08 33.5 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC79171.1 - 1.6e-14 53.7 2.7 0.00018 21.3 0.1 4.4 2 2 1 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC79171.1 - 2.8e-05 23.9 0.0 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 EMC79171.1 - 0.0075 16.0 0.1 6.4 6.5 0.0 2.8 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 EMC79171.1 - 0.0097 14.2 0.1 0.049 11.9 0.0 2.0 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1943 PF09172.6 EMC79172.1 - 8.4 5.1 9.4 11 4.7 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) Pkinase_Tyr PF07714.12 EMC79173.1 - 9.6e-52 175.6 0.0 1.2e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC79173.1 - 7.7e-48 162.9 0.0 1.9e-47 161.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 EMC79173.1 - 0.0024 17.2 1.0 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EMC79173.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC79173.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank PF00023.25 EMC79173.1 - 0.036 13.8 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Kinase-like PF14531.1 EMC79173.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ank_2 PF12796.2 EMC79173.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4590 PF15257.1 EMC79174.1 - 2.3e-58 195.0 0.5 3.1e-58 194.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) ADH_zinc_N PF00107.21 EMC79175.1 - 1.4e-25 89.3 1.1 5.7e-25 87.3 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC79175.1 - 2.8e-14 54.1 0.0 1e-13 52.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC79175.1 - 2.9e-14 52.7 0.2 3.7e-13 49.1 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EMC79175.1 - 0.0093 15.7 2.8 0.012 15.4 0.8 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TYW3 PF02676.9 EMC79176.1 - 1e-30 106.3 0.1 1.2e-30 106.2 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 Choline_transpo PF04515.7 EMC79177.1 - 6.3e-131 436.0 31.8 6.3e-131 436.0 22.1 2.8 3 0 0 3 3 3 2 Plasma-membrane choline transporter Acyl-CoA_dh_1 PF00441.19 EMC79178.1 - 5.1e-49 166.2 5.0 7.4e-49 165.7 3.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC79178.1 - 8.5e-28 97.1 0.1 1.6e-27 96.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMC79178.1 - 1e-22 79.3 0.1 2.1e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC79178.1 - 1.6e-21 76.9 2.9 2.5e-21 76.3 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EMC79178.1 - 0.00022 20.6 0.0 0.00091 18.6 0.0 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Prenyltrans PF00432.16 EMC79179.1 - 1.2e-71 235.8 8.3 3.1e-15 55.4 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMC79179.1 - 2.1e-29 102.1 0.0 6.4e-18 65.2 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC79179.1 - 2.1e-11 43.7 0.0 2e-09 37.4 0.0 3.2 4 1 0 4 4 4 1 Prenyltransferase-like BAG PF02179.11 EMC79179.1 - 0.071 13.2 0.0 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 BAG domain Methyltransf_16 PF10294.4 EMC79180.1 - 4.7e-13 48.9 0.4 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 EMC79180.1 - 1.9e-06 27.5 0.0 0.074 12.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EMC79180.1 - 3.6e-06 27.5 0.0 6.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC79180.1 - 5.9e-06 25.7 0.0 2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMC79180.1 - 6.8e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC79180.1 - 1.5e-05 24.3 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EMC79180.1 - 0.0001 22.7 0.1 0.00047 20.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMC79180.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EMC79180.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Ocnus PF05005.10 EMC79181.1 - 6.6e-31 106.3 0.5 7.1e-31 106.2 0.3 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Sushi PF00084.15 EMC79182.1 - 1.9e-47 159.4 72.0 2e-08 34.4 2.9 7.4 7 1 1 8 8 8 6 Sushi domain (SCR repeat) Lectin_C PF00059.16 EMC79182.1 - 8.5e-19 68.1 4.7 8.5e-19 68.1 3.2 2.5 3 0 0 3 3 3 1 Lectin C-type domain EGF_2 PF07974.8 EMC79182.1 - 0.00012 22.1 9.0 0.00012 22.1 6.2 4.7 4 0 0 4 4 4 1 EGF-like domain EGF PF00008.22 EMC79182.1 - 0.00033 20.5 10.1 0.00033 20.5 7.0 4.4 7 0 0 7 7 7 1 EGF-like domain EGF_3 PF12947.2 EMC79182.1 - 0.015 15.2 5.2 0.015 15.2 3.6 6.3 7 0 0 7 7 7 0 EGF domain Hormone_recep PF00104.25 EMC79183.1 - 2.9e-41 140.8 0.0 4.2e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.3 EMC79183.1 - 1.4e-33 115.1 16.3 1.4e-33 115.1 11.3 1.6 2 0 0 2 2 2 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.13 EMC79183.1 - 4.3e-32 110.1 15.7 7.2e-32 109.4 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PBC PF03792.8 EMC79184.1 - 2.7e-71 239.2 0.0 3.9e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 EMC79184.1 - 5.9e-20 70.6 0.9 1.4e-19 69.4 0.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79184.1 - 5e-16 58.1 0.0 2.8e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.17 EMC79184.1 - 0.0077 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EMC79184.1 - 0.0082 16.1 0.1 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1319 PF07028.6 EMC79184.1 - 0.0094 16.1 0.6 0.021 15.0 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Sec15 PF04091.7 EMC79184.1 - 0.01 15.1 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Homez PF11569.3 EMC79184.1 - 0.017 14.1 0.0 0.04 12.9 0.0 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.1 EMC79184.1 - 0.025 14.8 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.8 EMC79184.1 - 0.047 13.1 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NUC130_3NT PF08158.7 EMC79184.1 - 0.27 11.5 1.0 8.1 6.8 0.0 3.2 3 1 0 3 3 3 0 NUC130/3NT domain Nuf2 PF03800.9 EMC79185.1 - 1.8e-36 125.2 0.5 1.8e-36 125.2 0.4 2.6 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 EMC79185.1 - 0.16 11.0 7.2 2.5 7.1 0.8 2.5 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EMC79185.1 - 0.95 8.3 56.6 11 4.8 20.1 4.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 A2M_recep PF07677.9 EMC79185.1 - 0.96 9.6 7.1 4.1 7.6 0.5 3.2 2 1 0 2 2 2 0 A-macroglobulin receptor LRR_8 PF13855.1 EMC79186.1 - 1.1e-16 60.3 10.4 8.8e-09 35.0 0.3 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC79186.1 - 1.2e-13 50.3 3.4 0.0022 17.5 0.0 3.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC79186.1 - 3.2e-08 32.5 10.3 0.0092 15.8 0.1 6.6 6 1 1 7 7 7 3 Leucine Rich Repeat LRRNT PF01462.13 EMC79186.1 - 2.7e-05 23.5 0.9 2.7e-05 23.5 0.6 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 EMC79186.1 - 0.00026 20.7 12.5 1.5 9.1 0.0 5.7 5 1 0 5 5 5 2 Leucine Rich repeat LRR_5 PF13306.1 EMC79186.1 - 0.0055 16.4 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC79186.1 - 0.014 15.5 15.7 4.6 7.8 0.0 6.0 8 0 0 8 8 8 0 Leucine rich repeat MAPEG PF01124.13 EMC79187.1 - 1.7e-24 85.8 0.3 2e-24 85.6 0.2 1.1 1 0 0 1 1 1 1 MAPEG family DmsC PF04976.7 EMC79187.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) Aldedh PF00171.17 EMC79188.1 - 2.4e-167 556.9 0.0 2.8e-167 556.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF106 PF01956.11 EMC79189.1 - 3e-47 160.2 1.2 3.6e-47 160.0 0.8 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 ATG19_autophagy PF12744.2 EMC79189.1 - 0.0014 17.9 0.9 0.0019 17.4 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding Vpu PF00558.14 EMC79189.1 - 0.0059 16.1 1.2 0.011 15.2 0.8 1.5 1 1 0 1 1 1 1 Vpu protein Exonuc_VII_L PF02601.10 EMC79189.1 - 0.012 14.7 0.1 0.012 14.7 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SieB PF14163.1 EMC79189.1 - 0.02 14.4 2.0 0.021 14.3 0.5 1.7 2 0 0 2 2 2 0 Superinfection exclusion protein B TRAM1 PF08390.6 EMC79189.1 - 0.028 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 TRAM1-like protein Bap31 PF05529.7 EMC79189.1 - 0.039 13.4 3.5 0.071 12.5 2.4 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pox_LP_H2 PF03356.10 EMC79189.1 - 0.043 13.5 0.7 0.058 13.0 0.5 1.3 1 0 0 1 1 1 0 Viral late protein H2 DUF4199 PF13858.1 EMC79189.1 - 0.06 13.2 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Nucleoside_tran PF01733.13 EMC79189.1 - 0.12 11.4 3.0 0.11 11.6 0.8 1.7 1 1 1 2 2 2 0 Nucleoside transporter OmpH PF03938.9 EMC79189.1 - 0.29 11.0 7.0 0.45 10.4 4.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1090 PF06476.7 EMC79189.1 - 0.9 9.2 12.6 1.4 8.5 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Atg14 PF10186.4 EMC79189.1 - 0.91 8.4 5.0 1.2 7.9 3.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EMC79189.1 - 0.98 8.9 11.4 0.23 10.9 0.8 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4337 PF14235.1 EMC79189.1 - 2.5 7.9 7.7 2.7 7.8 4.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) UPF0233 PF06781.7 EMC79189.1 - 4.3 7.0 5.4 5.1 6.7 0.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) DUF874 PF05917.6 EMC79189.1 - 6.3 5.5 11.1 8.5 5.1 7.7 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) PRK PF00485.13 EMC79190.1 - 3.7e-46 157.1 0.7 4.3e-46 156.9 0.5 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EMC79190.1 - 0.15 12.3 0.5 0.41 10.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain Cytochrom_C PF00034.16 EMC79191.1 - 1.2e-12 48.4 0.1 1.7e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EMC79191.1 - 2.5e-07 30.7 3.4 2e-06 27.8 2.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EMC79191.1 - 6.6e-05 22.3 3.5 0.00095 18.6 2.4 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain UPF0128 PF03673.8 EMC79191.1 - 0.01 15.1 0.2 0.01 15.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Cytochrom_C1 PF02167.10 EMC79191.1 - 0.14 11.8 0.3 0.16 11.5 0.2 1.4 1 1 0 1 1 1 0 Cytochrome C1 family Hexokinase_1 PF00349.16 EMC79192.1 - 0.08 12.2 0.1 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Hexokinase NPFF PF15085.1 EMC79192.1 - 0.27 11.5 2.4 2.6 8.3 1.5 2.6 1 1 0 1 1 1 0 Neuropeptide FF FARP PF01581.11 EMC79192.1 - 3.2 8.4 7.3 64 4.5 0.0 4.1 4 0 0 4 4 4 0 FMRFamide related peptide family bZIP_Maf PF03131.12 EMC79193.1 - 0.0046 17.2 5.5 0.0062 16.7 0.4 2.7 2 1 1 3 3 3 1 bZIP Maf transcription factor RRM_1 PF00076.17 EMC79194.1 - 2.6e-37 126.2 0.0 3.2e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79194.1 - 1.6e-33 114.5 0.0 8e-17 60.9 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79194.1 - 9.8e-12 44.5 0.0 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EMC79194.1 - 0.012 15.0 0.5 0.52 9.8 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain NID PF07292.8 EMC79194.1 - 0.54 10.3 0.1 0.54 10.3 0.0 2.8 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) Chromo_shadow PF01393.14 EMC79195.1 - 9.1e-41 137.5 0.0 5.6e-35 118.9 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 EMC79195.1 - 1.3e-22 79.2 0.2 3.9e-17 61.6 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EMC79195.1 - 0.012 15.5 0.2 0.031 14.1 0.1 1.7 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 PX PF00787.19 EMC79196.1 - 4.8e-24 84.3 3.0 6.5e-24 83.8 2.1 1.2 1 0 0 1 1 1 1 PX domain PH PF00169.24 EMC79197.1 - 1.1e-13 51.2 0.8 1.9e-13 50.5 0.2 1.6 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 EMC79197.1 - 1.5e-11 43.4 0.3 4.3e-11 42.0 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC79197.1 - 2.5e-11 42.9 0.2 6.3e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC79197.1 - 6.6e-11 41.5 0.1 1.5e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_9 PF15410.1 EMC79197.1 - 8.8e-06 25.8 0.2 2.3e-05 24.5 0.2 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMC79197.1 - 4.8e-05 23.1 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC79197.1 - 0.00022 21.4 2.6 0.0014 18.8 1.8 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.5 EMC79197.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Homeobox PF00046.24 EMC79198.1 - 2.2e-22 78.4 7.4 3.2e-22 77.9 5.1 1.2 1 0 0 1 1 1 1 Homeobox domain YcgR PF07317.7 EMC79198.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Flagellar regulator YcgR DUF4074 PF13293.1 EMC79199.1 - 7.3e-37 125.4 8.4 7.3e-37 125.4 5.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4074) Homeobox PF00046.24 EMC79199.1 - 9.7e-22 76.3 5.0 2.1e-21 75.3 3.5 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 EMC79200.1 - 6e-24 83.4 8.9 7.7e-24 83.0 6.1 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79200.1 - 0.012 15.2 0.7 0.012 15.2 0.5 1.5 2 0 0 2 2 2 0 Homeobox KN domain DUF2209 PF09974.4 EMC79200.1 - 0.029 14.4 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Terminase_5 PF06056.7 EMC79200.1 - 0.039 13.5 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.1 EMC79200.1 - 0.057 13.0 0.9 0.079 12.6 0.6 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 EMC79201.1 - 2e-22 78.5 8.1 4e-22 77.5 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79201.1 - 0.02 14.6 2.1 0.055 13.1 0.7 2.2 2 0 0 2 2 2 0 Homeobox KN domain Terminase_5 PF06056.7 EMC79201.1 - 0.078 12.5 0.3 0.21 11.1 0.2 1.7 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF605 PF04652.11 EMC79201.1 - 2 7.7 11.8 2.3 7.5 8.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 EMC79201.1 - 6.2 6.2 8.4 8 5.8 5.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Homeobox PF00046.24 EMC79202.1 - 7.6e-22 76.6 8.8 7.6e-22 76.6 6.1 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EMC79202.1 - 0.032 13.9 1.7 0.032 13.9 1.2 1.8 2 0 0 2 2 2 0 Homeobox KN domain Homeobox PF00046.24 EMC79203.1 - 3.9e-22 77.6 8.2 6.1e-22 77.0 5.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79203.1 - 0.021 14.5 1.1 0.041 13.5 0.8 1.5 1 0 0 1 1 1 0 Homeobox KN domain Hanta_G1 PF01567.11 EMC79203.1 - 0.12 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 Homeobox PF00046.24 EMC79204.1 - 1.4e-22 79.0 6.4 1.7e-22 78.7 4.5 1.1 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EMC79204.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain CI-B14_5a PF07347.7 EMC79204.1 - 0.068 12.9 0.2 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homeobox PF00046.24 EMC79205.1 - 9.2e-21 73.2 6.1 1.6e-20 72.4 4.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79205.1 - 0.11 12.2 0.2 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain RNA_pol_Rpc4 PF05132.9 EMC79205.1 - 0.45 10.4 2.4 0.85 9.6 1.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Homeobox PF00046.24 EMC79206.1 - 1.3e-19 69.5 7.9 1.5e-19 69.3 5.5 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79206.1 - 0.00029 20.4 2.0 0.00044 19.8 1.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC79206.1 - 0.0059 15.6 0.1 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.1 EMC79206.1 - 0.12 12.0 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 EMC79207.1 - 3.7e-21 74.5 4.6 6.1e-21 73.8 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain NAD_binding_2 PF03446.10 EMC79208.1 - 1.2e-53 181.2 0.3 1.7e-53 180.7 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC79208.1 - 7.5e-38 129.3 0.0 1.2e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EMC79208.1 - 2.6e-10 39.7 0.0 4.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMC79208.1 - 3.2e-09 37.1 0.0 8.8e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EMC79208.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMC79208.1 - 0.0012 18.8 0.0 0.0038 17.2 0.0 2.0 1 1 0 1 1 1 1 TrkA-N domain PDH PF02153.12 EMC79208.1 - 0.002 17.0 0.1 0.0026 16.7 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMC79208.1 - 0.0025 17.2 0.1 0.13 11.6 0.0 2.2 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 EMC79208.1 - 0.0029 16.9 0.1 0.0053 16.1 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EMC79208.1 - 0.037 13.7 0.0 0.083 12.6 0.0 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EMC79208.1 - 0.068 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.8 EMC79208.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family zf-C2H2_4 PF13894.1 EMC79209.1 - 0.014 15.7 5.0 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC79209.1 - 0.033 14.5 6.7 1.3 9.4 1.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC79209.1 - 2.6 8.4 15.5 1.7 9.1 1.2 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Mab-21 PF03281.9 EMC79210.1 - 7.8e-71 238.5 0.4 1.1e-70 238.1 0.3 1.2 1 0 0 1 1 1 1 Mab-21 protein CCDC50_N PF15295.1 EMC79211.1 - 1e-51 174.3 42.5 3.7e-48 162.8 17.9 2.2 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus DUF2572 PF10833.3 EMC79211.1 - 1.7 7.9 6.7 1.2 8.5 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2572) CutA1 PF03091.10 EMC79211.1 - 3.6 7.3 5.4 0.31 10.7 0.2 2.0 3 0 0 3 3 3 0 CutA1 divalent ion tolerance protein DUF3048 PF11258.3 EMC79211.1 - 4.1 6.4 8.6 0.26 10.4 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) Urotensin_II PF02083.10 EMC79212.1 - 6.5e-05 22.0 4.4 0.00012 21.2 3.1 1.4 1 0 0 1 1 1 1 Urotensin II Mei5 PF10376.4 EMC79212.1 - 0.06 12.8 4.5 0.077 12.5 3.1 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein Musclin PF11037.3 EMC79213.1 - 2.7e-65 217.9 0.1 3e-65 217.7 0.1 1.0 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle ANP PF00212.13 EMC79213.1 - 6.6e-05 22.9 0.2 0.38 10.8 0.0 2.4 2 0 0 2 2 2 2 Atrial natriuretic peptide TIR PF01582.15 EMC79214.1 - 0.00021 20.7 0.1 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 TIR domain DUF4620 PF15399.1 EMC79214.1 - 0.018 15.1 0.5 0.018 15.1 0.3 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4620) TMEM52 PF14979.1 EMC79215.1 - 0.00059 19.7 13.6 0.018 14.9 9.4 2.1 1 1 0 1 1 1 1 Transmembrane 52 Hum_adeno_E3A PF05393.6 EMC79215.1 - 0.047 13.3 3.0 0.074 12.7 2.1 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein 7tm_1 PF00001.16 EMC79215.1 - 0.089 11.9 1.8 0.1 11.7 1.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) WBP-1 PF11669.3 EMC79215.1 - 0.18 11.9 7.1 0.47 10.5 4.3 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 PMP22_Claudin PF00822.15 EMC79216.1 - 2.7e-19 69.4 7.9 3.6e-19 69.0 5.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC79216.1 - 3.8e-12 46.2 6.8 5.6e-12 45.6 4.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.6 EMC79216.1 - 1.9 8.2 7.4 3.6 7.2 5.1 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 EMC79217.1 - 9.2e-51 171.7 10.2 1.1e-50 171.5 7.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC79217.1 - 2.6e-13 50.0 9.9 3.5e-13 49.6 6.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 EMC79217.1 - 3.8e-05 23.6 2.7 0.04 13.8 0.2 2.5 2 1 1 3 3 3 2 CD20-like family Amastin PF07344.6 EMC79217.1 - 0.0096 15.5 8.4 0.015 14.9 5.8 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.7 EMC79217.1 - 0.011 15.2 2.4 0.011 15.2 1.7 1.9 1 1 1 2 2 2 0 SUR7/PalI family DUF897 PF05982.7 EMC79217.1 - 0.019 13.7 1.2 0.033 13.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF897) DoxX PF07681.7 EMC79217.1 - 0.12 12.8 4.8 0.15 12.5 0.4 2.4 2 0 0 2 2 2 0 DoxX DUF4282 PF14110.1 EMC79217.1 - 0.22 11.7 7.1 0.33 11.1 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) MIG-14_Wnt-bd PF06664.7 EMC79217.1 - 0.25 10.1 3.5 0.14 10.9 1.0 1.6 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF898 PF05987.8 EMC79217.1 - 0.47 9.2 10.3 1.1 8.0 7.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF1218 PF06749.7 EMC79217.1 - 0.54 10.7 8.1 0.47 10.9 1.9 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1218) MgtE PF01769.11 EMC79217.1 - 0.79 10.0 5.4 0.12 12.6 1.1 1.6 2 0 0 2 2 2 0 Divalent cation transporter Shisa PF13908.1 EMC79217.1 - 1.1 9.4 4.3 3.4 7.7 1.5 2.6 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator OppC_N PF12911.2 EMC79217.1 - 1.3 8.4 0.0 1.3 8.4 0.0 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Tetraspannin PF00335.15 EMC79217.1 - 1.8 7.7 15.7 1.4 8.0 1.7 2.5 1 1 1 2 2 2 0 Tetraspanin family DUF4064 PF13273.1 EMC79217.1 - 3.8 7.6 13.0 11 6.1 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ARGLU PF15346.1 EMC79218.1 - 8.2 6.1 42.0 13 5.5 13.2 2.1 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 2OG-FeII_Oxy_3 PF13640.1 EMC79219.1 - 4.7e-15 55.9 0.0 4.1e-14 52.8 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMC79219.1 - 4.3e-05 23.0 0.1 0.00018 21.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMC79219.1 - 4.9e-05 23.5 0.0 0.00015 22.0 0.0 1.9 2 0 0 2 2 1 1 2OG-Fe(II) oxygenase superfamily TPR_11 PF13414.1 EMC79219.1 - 0.00089 18.8 3.6 0.074 12.7 0.1 2.9 2 1 1 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.1 EMC79219.1 - 0.0018 18.1 1.1 0.0091 15.8 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EMC79219.1 - 0.0036 17.8 0.8 0.59 10.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC79219.1 - 0.0056 16.5 6.4 0.99 9.4 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC79219.1 - 0.0083 15.8 3.5 3.9 7.4 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC79219.1 - 0.0089 15.6 6.5 0.55 9.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat YfiO PF13525.1 EMC79219.1 - 0.011 15.2 5.7 0.29 10.5 0.1 3.1 3 0 0 3 3 3 0 Outer membrane lipoprotein Oxygenase-NA PF09859.4 EMC79219.1 - 0.011 15.1 0.0 0.23 10.7 0.0 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA TPR_9 PF13371.1 EMC79219.1 - 0.025 14.4 1.4 0.33 10.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_9 PF08021.6 EMC79219.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain TPR_12 PF13424.1 EMC79219.1 - 0.1 12.5 2.9 2.2 8.2 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat P53 PF00870.13 EMC79220.1 - 5e-108 359.0 2.2 1.5e-107 357.5 0.5 2.1 2 0 0 2 2 2 1 P53 DNA-binding domain P53_tetramer PF07710.6 EMC79220.1 - 3.4e-18 64.4 0.3 6.1e-18 63.6 0.2 1.5 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.12 EMC79220.1 - 7.5e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LIM PF00412.17 EMC79221.1 - 2e-34 117.4 28.5 2.7e-13 49.7 5.0 3.3 3 0 0 3 3 3 3 LIM domain BTB PF00651.26 EMC79222.1 - 2.5e-27 95.0 0.3 4.4e-27 94.2 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC79222.1 - 1.6e-25 88.0 54.4 1.4e-07 31.4 0.4 6.9 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79222.1 - 8.3e-18 63.5 57.9 4.1e-05 23.6 0.2 7.6 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-met PF12874.2 EMC79222.1 - 2.4e-11 43.4 32.2 0.0076 16.4 0.1 7.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMC79222.1 - 6.6e-11 41.7 59.9 0.011 15.9 0.4 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79222.1 - 7.1e-10 38.7 19.7 0.047 13.8 1.4 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC79222.1 - 0.0071 16.2 34.9 0.056 13.3 0.2 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger DUF3342 PF11822.3 EMC79222.1 - 0.008 15.3 0.5 0.008 15.3 0.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) zf-H2C2_5 PF13909.1 EMC79222.1 - 0.18 12.1 0.1 0.18 12.1 0.1 6.6 7 1 0 7 7 6 0 C2H2-type zinc-finger domain MCP_N PF05581.7 EMC79222.1 - 0.2 11.8 0.3 0.64 10.1 0.0 1.9 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus GAGA PF09237.6 EMC79222.1 - 1.1 8.9 17.2 5.9 6.5 0.0 5.1 1 1 4 5 5 5 0 GAGA factor Somatostatin PF03002.10 EMC79223.1 - 2.2e-12 46.2 8.1 3.1e-12 45.7 5.6 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family Gon7 PF08738.5 EMC79224.1 - 0.0078 16.1 0.2 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 Gon7 family YjfB_motility PF14070.1 EMC79224.1 - 0.064 13.0 0.2 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 Putative motility protein Trypsin PF00089.21 EMC79225.1 - 4e-56 190.0 0.0 5.9e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 EMC79225.1 - 2.7e-49 165.8 0.9 2.6e-28 98.2 0.1 2.5 2 0 0 2 2 2 2 CUB domain Sushi PF00084.15 EMC79225.1 - 1.8e-13 50.5 18.8 1.6e-07 31.5 0.3 4.3 4 0 0 4 4 4 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 EMC79225.1 - 8.3e-09 35.4 11.0 8.4e-08 32.2 5.8 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site CUB_2 PF02408.15 EMC79225.1 - 5.3e-06 25.9 0.2 0.013 15.0 0.0 2.9 3 0 0 3 3 3 2 CUB-like domain EGF_CA PF07645.10 EMC79225.1 - 2.3e-05 24.2 7.9 2.3e-05 24.2 5.5 2.6 3 0 0 3 3 3 1 Calcium-binding EGF domain Trypsin_2 PF13365.1 EMC79225.1 - 8.1e-05 22.5 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.2 EMC79225.1 - 0.0041 16.7 3.6 0.0041 16.7 2.5 3.1 3 0 0 3 3 3 1 Complement Clr-like EGF-like V-set PF07686.12 EMC79226.1 - 5.9e-11 42.2 0.1 8.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC79226.1 - 0.00063 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC79226.1 - 0.0019 18.2 2.3 0.041 14.0 1.6 2.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC79226.1 - 0.002 17.9 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain IncA PF04156.9 EMC79226.1 - 0.077 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 EMC79226.1 - 0.089 11.0 0.0 0.26 9.4 0.0 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Tctex-1 PF03645.8 EMC79227.1 - 4.1e-26 90.8 0.0 4.5e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family CTP_transf_2 PF01467.21 EMC79228.1 - 5.7e-23 81.6 0.5 9.2e-23 81.0 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase GldM_N PF12081.3 EMC79228.1 - 0.026 14.0 0.4 0.04 13.4 0.3 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Lipoprotein_6 PF01441.14 EMC79228.1 - 0.11 12.3 3.2 0.18 11.6 2.2 1.3 1 0 0 1 1 1 0 Lipoprotein KH_5 PF13184.1 EMC79228.1 - 0.33 10.7 3.2 0.44 10.3 1.3 1.8 2 0 0 2 2 2 0 NusA-like KH domain Solute_trans_a PF03619.11 EMC79229.1 - 2.5e-18 66.3 7.8 3.1e-18 66.0 5.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TFR_dimer PF04253.10 EMC79230.1 - 1.9e-27 95.2 0.0 3.8e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMC79230.1 - 2.6e-11 43.5 0.0 6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMC79230.1 - 0.00013 21.6 0.1 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 PA domain Pkinase_Tyr PF07714.12 EMC79231.1 - 7.4e-89 297.2 0.0 1e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC79231.1 - 4e-43 147.4 0.0 6.9e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GTPase_binding PF09027.5 EMC79231.1 - 8.7e-31 105.3 0.1 1.9e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 GTPase binding Inhibitor_Mig-6 PF11555.3 EMC79231.1 - 1.5e-28 98.9 12.5 1.5e-28 98.9 8.7 3.5 3 0 0 3 3 3 1 EGFR receptor inhibitor Mig-6 SH3_9 PF14604.1 EMC79231.1 - 3.5e-10 39.3 0.0 7.5e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UBA_4 PF14555.1 EMC79231.1 - 6e-08 32.0 0.0 0.0043 16.5 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain UBA PF00627.26 EMC79231.1 - 1.5e-07 31.0 0.0 1.6e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Kinase-like PF14531.1 EMC79231.1 - 8.2e-07 28.2 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_1 PF00018.23 EMC79231.1 - 1.1e-06 27.8 0.0 2.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC79231.1 - 0.00015 21.1 0.0 0.00039 19.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF2345 PF10106.4 EMC79232.1 - 2.3 7.8 58.1 0.33 10.5 1.9 5.4 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2345) Cornifin PF02389.10 EMC79232.1 - 7.4 6.2 17.6 2 8.1 6.0 2.1 1 1 1 2 2 2 0 Cornifin (SPRR) family UPF0016 PF01169.14 EMC79232.1 - 7.6 6.7 30.9 5.5 7.2 2.1 6.6 1 1 6 7 7 7 0 Uncharacterized protein family UPF0016 VWD PF00094.20 EMC79233.1 - 3.5e-17 63.0 0.0 7.1e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain AMOP PF03782.12 EMC79233.1 - 7.6e-06 26.0 8.2 0.00013 21.9 3.1 3.4 2 1 0 2 2 2 1 AMOP domain NIDO PF06119.9 EMC79233.1 - 0.0001 22.9 0.0 0.00035 21.2 0.0 2.0 1 0 0 1 1 1 1 Nidogen-like AMOP PF03782.12 EMC79234.1 - 0.012 15.6 1.8 0.075 13.0 1.2 1.9 1 1 0 1 1 1 0 AMOP domain NIDO PF06119.9 EMC79235.1 - 6.5e-09 36.3 1.0 7.9e-09 36.1 0.2 1.5 2 0 0 2 2 2 1 Nidogen-like FAD_binding_7 PF03441.9 EMC79236.1 - 4.5e-36 124.4 3.8 6.5e-36 123.9 1.5 2.0 2 1 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMC79236.1 - 1.4e-22 80.2 0.0 2.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF4206 PF13901.1 EMC79238.1 - 6.6e-73 244.5 14.4 6.6e-73 244.5 10.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4206) RUN PF02759.14 EMC79238.1 - 5.8e-10 39.0 0.1 1.4e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 RUN domain FYTT PF07078.6 EMC79239.1 - 4.9e-116 387.4 16.1 5.6e-116 387.2 11.2 1.0 1 0 0 1 1 1 1 Forty-two-three protein DUF1013 PF06242.6 EMC79239.1 - 0.18 11.7 0.2 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) LRR_4 PF12799.2 EMC79240.1 - 4.1e-25 86.9 17.3 1.3e-07 31.1 0.7 5.6 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79240.1 - 1.6e-22 79.0 13.1 1.1e-09 37.8 0.6 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EMC79240.1 - 2e-16 57.4 23.9 0.044 13.7 0.0 9.2 8 1 0 8 8 8 6 Leucine Rich Repeat CH PF00307.26 EMC79240.1 - 2e-10 40.6 0.0 4.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 EMC79240.1 - 1.2e-08 33.7 19.0 0.25 11.6 0.2 8.3 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 EMC79240.1 - 1.6e-05 24.5 14.8 1.2 9.4 0.4 7.6 9 0 0 9 9 9 2 Leucine Rich repeat CAMSAP_CH PF11971.3 EMC79240.1 - 0.00045 19.8 0.1 0.0015 18.1 0.0 1.9 2 0 0 2 2 2 1 CAMSAP CH domain IQ PF00612.22 EMC79241.1 - 0.00027 20.3 0.2 0.00027 20.3 0.1 2.3 3 0 0 3 3 3 1 IQ calmodulin-binding motif Baculo_PEP_C PF04513.7 EMC79241.1 - 0.011 15.6 7.3 0.032 14.0 0.8 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RuvC PF02075.12 EMC79241.1 - 0.1 12.4 1.1 0.8 9.5 0.1 2.4 1 1 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC DUF3086 PF11285.3 EMC79241.1 - 0.35 9.6 9.9 0.61 8.8 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Pox_A_type_inc PF04508.7 EMC79241.1 - 2 8.4 10.1 0.34 10.8 1.1 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Ribosomal_L35Ae PF01247.13 EMC79242.1 - 5.6e-43 144.6 0.8 6.2e-43 144.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EMC79242.1 - 0.073 12.9 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain DUF4630 PF15443.1 EMC79243.1 - 0.00029 20.6 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4630) PC_rep PF01851.17 EMC79244.1 - 2.4e-48 159.7 15.9 8.8e-09 35.1 0.0 9.0 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMC79244.1 - 2.3e-20 72.6 0.8 7.6e-13 48.5 0.0 5.4 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EMC79244.1 - 2.3e-08 33.4 0.3 0.63 10.2 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EMC79244.1 - 2.2e-07 31.1 0.1 0.011 16.1 0.0 4.6 4 1 0 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.11 EMC79244.1 - 0.0015 18.8 1.6 5.5 7.7 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Tim54 PF11711.3 EMC79244.1 - 0.15 10.6 7.0 0.24 9.9 4.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tom37_C PF11801.3 EMC79244.1 - 0.15 11.9 4.6 0.33 10.8 3.2 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain PcfK PF14058.1 EMC79244.1 - 2.6 8.1 15.2 6.1 6.9 10.5 1.6 1 0 0 1 1 1 0 PcfK-like protein NARP1 PF12569.3 EMC79244.1 - 3.4 6.3 11.1 7.1 5.2 7.7 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TBX PF12598.3 EMC79244.1 - 7.5 7.0 15.1 0.24 11.8 0.3 2.4 2 0 0 2 2 2 0 T-box transcription factor 7tm_1 PF00001.16 EMC79245.1 - 7e-69 231.8 12.8 9.9e-69 231.3 8.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC79245.1 - 2.1e-12 46.7 13.0 7e-12 45.0 9.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC79245.1 - 3.3e-05 23.1 7.8 3.3e-05 23.1 5.4 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3930 PF13067.1 EMC79245.1 - 1.8 8.4 5.3 0.33 10.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) CENP-B_dimeris PF09026.5 EMC79246.1 - 0.0091 16.2 3.5 0.0091 16.2 2.4 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FOP_dimer PF09398.5 EMC79246.1 - 0.013 15.4 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 0 FOP N terminal dimerisation domain TFIIA PF03153.8 EMC79246.1 - 0.042 13.7 0.1 0.088 12.6 0.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HEAT_2 PF13646.1 EMC79246.1 - 0.065 13.5 0.5 0.53 10.6 0.1 2.6 1 1 0 2 2 2 0 HEAT repeats Galactosyl_T PF01762.16 EMC79247.1 - 2.4e-49 167.5 0.0 3.5e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC79247.1 - 1.7e-08 34.0 0.0 5.2e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Fringe-like RRM_1 PF00076.17 EMC79248.1 - 1.5e-64 213.5 9.2 4.4e-17 61.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79248.1 - 4.6e-49 164.2 1.3 3.8e-14 52.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79248.1 - 2.1e-27 94.7 0.1 5.5e-07 29.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC79248.1 - 0.00027 20.6 3.1 0.63 9.8 0.0 4.4 3 1 1 4 4 4 1 Limkain b1 PTRF_SDPR PF15237.1 EMC79248.1 - 0.00048 19.5 0.1 0.00048 19.5 0.0 3.6 1 1 2 3 3 3 1 PTRF/SDPR family DUF4283 PF14111.1 EMC79248.1 - 0.0032 16.5 0.0 0.66 9.0 0.0 3.1 2 1 0 3 3 3 1 Domain of unknown function (DUF4283) DbpA PF03880.10 EMC79248.1 - 0.069 12.8 0.1 1.8 8.2 0.0 3.2 4 0 0 4 4 4 0 DbpA RNA binding domain Nup35_RRM_2 PF14605.1 EMC79248.1 - 0.087 12.6 0.0 7.8 6.3 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif 7tm_1 PF00001.16 EMC79249.1 - 2.5e-54 184.1 13.0 4e-54 183.4 9.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC79249.1 - 5.7e-09 35.5 14.7 1.5e-08 34.0 10.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 EMC79249.1 - 1.2e-06 27.8 19.2 9.6e-05 21.6 13.3 3.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.4 EMC79249.1 - 0.00025 20.2 13.4 0.00061 18.9 9.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx GMP_PDE_delta PF05351.6 EMC79254.1 - 3.2e-44 150.4 0.0 3.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit PQQ PF01011.16 EMC79254.1 - 0.065 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat PCI PF01399.22 EMC79255.1 - 2.7e-12 46.9 2.4 1.3e-11 44.7 0.1 2.3 2 0 0 2 2 2 1 PCI domain ATPase-cat_bd PF12156.3 EMC79255.1 - 0.068 13.7 0.4 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Band_3_cyto PF07565.8 EMC79255.1 - 0.26 10.7 7.1 0.66 9.4 4.9 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain RNB PF00773.14 EMC79256.1 - 3.1e-61 207.4 0.0 3.8e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 RNB domain Alk_phosphatase PF00245.15 EMC79257.1 - 1.2e-156 521.7 0.0 1.3e-156 521.5 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EMC79257.1 - 0.026 13.9 0.1 0.05 12.9 0.1 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Alk_phosphatase PF00245.15 EMC79258.1 - 3.8e-161 536.4 0.1 4.3e-161 536.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EMC79258.1 - 0.0056 16.0 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Peptidase_M13_N PF05649.8 EMC79259.1 - 1.6e-79 267.7 1.2 2.2e-79 267.2 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EMC79259.1 - 6.3e-65 218.2 0.1 1e-64 217.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 AA_permease PF00324.16 EMC79261.1 - 4.4e-70 236.3 24.1 4.4e-70 236.3 16.7 1.8 1 1 1 2 2 2 2 Amino acid permease Trypsin PF00089.21 EMC79262.1 - 1.5e-72 243.7 0.0 1.7e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC79262.1 - 2.5e-09 36.8 0.0 3.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC79262.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Neur_chan_LBD PF02931.18 EMC79263.1 - 1e-67 227.4 0.3 1.3e-67 227.0 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC79263.1 - 3.1e-65 220.3 0.1 4.2e-65 219.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 7tm_3 PF00003.17 EMC79263.1 - 0.00066 19.0 4.1 0.0063 15.8 1.8 2.7 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR IF4E PF01652.13 EMC79264.1 - 1.4e-61 206.8 0.1 1.9e-61 206.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E p450 PF00067.17 EMC79265.1 - 4.8e-119 397.9 0.0 5.5e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC79266.1 - 2.4e-125 418.6 0.3 2.7e-125 418.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC79267.1 - 6.8e-106 354.5 0.0 7.8e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec62 PF03839.11 EMC79268.1 - 2e-92 308.6 6.4 2e-92 308.6 4.4 2.5 2 1 1 3 3 3 1 Translocation protein Sec62 OPT PF03169.10 EMC79268.1 - 0.016 13.6 0.0 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Ycf1 PF05758.7 EMC79268.1 - 0.029 12.1 18.3 0.017 12.8 0.8 2.1 2 0 0 2 2 2 0 Ycf1 DEP PF00610.16 EMC79268.1 - 0.045 13.4 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SAPS PF04499.10 EMC79268.1 - 0.23 10.0 0.0 0.23 10.0 0.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BUD22 PF09073.5 EMC79268.1 - 0.36 9.8 53.0 0.37 9.8 9.8 2.1 2 0 0 2 2 2 0 BUD22 SAM_1 PF00536.25 EMC79269.1 - 7.5e-12 45.2 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC79269.1 - 3.8e-09 36.2 0.0 8.2e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_6 PF13516.1 EMC79270.1 - 7.4e-19 65.6 46.0 0.14 12.3 0.0 14.5 14 1 1 15 15 15 9 Leucine Rich repeat LRR_4 PF12799.2 EMC79270.1 - 7.5e-16 57.3 43.1 0.0006 19.3 0.0 9.8 3 1 10 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79270.1 - 7.4e-13 48.0 41.6 5.4e-05 22.8 1.1 8.8 4 3 5 9 9 9 7 Leucine rich repeat LRR_7 PF13504.1 EMC79270.1 - 9.7e-13 46.0 38.7 2.7 8.5 0.4 14.1 15 0 0 15 15 15 4 Leucine rich repeat LRR_1 PF00560.28 EMC79270.1 - 1.2e-12 45.9 36.6 1.9 8.8 0.0 13.4 11 2 2 13 13 13 6 Leucine Rich Repeat PYRIN PF02758.11 EMC79270.1 - 0.00049 19.7 0.5 0.11 12.1 0.0 2.9 2 0 0 2 2 2 1 PAAD/DAPIN/Pyrin domain DUF2780 PF11075.3 EMC79270.1 - 0.18 11.8 2.6 2.4 8.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) zf-H2C2_2 PF13465.1 EMC79271.1 - 4.9e-59 193.8 43.2 3.1e-09 36.6 0.1 9.4 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79271.1 - 3.3e-37 124.5 53.4 5.1e-06 26.5 0.3 8.9 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79271.1 - 3.4e-26 89.6 51.6 0.00047 20.2 1.6 9.0 9 0 0 9 9 8 8 C2H2-type zinc finger BTB PF00651.26 EMC79271.1 - 3e-24 85.1 0.2 7.1e-24 83.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 EMC79271.1 - 4.6e-14 52.0 31.2 0.026 14.6 0.0 8.5 9 0 0 9 9 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC79271.1 - 3.5e-12 45.7 36.5 0.062 13.2 0.0 8.8 8 1 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.2 EMC79271.1 - 8.8e-07 28.9 52.1 0.002 18.2 0.3 8.9 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC79271.1 - 0.00028 20.9 31.7 0.062 13.4 0.4 5.5 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 EMC79271.1 - 0.0086 15.8 0.3 0.0086 15.8 0.2 7.6 3 2 5 8 8 8 2 BED zinc finger XPA_N PF01286.13 EMC79271.1 - 0.24 11.0 25.1 23 4.7 0.0 7.7 8 0 0 8 8 8 0 XPA protein N-terminal DUF1610 PF07754.6 EMC79271.1 - 0.67 10.1 0.0 0.67 10.1 0.0 6.3 7 0 0 7 7 7 0 Domain of unknown function (DUF1610) C1_4 PF07975.7 EMC79271.1 - 0.85 9.6 30.4 2.6 8.0 4.8 6.2 1 1 6 7 7 7 0 TFIIH C1-like domain RRN7 PF11781.3 EMC79271.1 - 6.5 6.3 17.1 51 3.4 0.2 6.7 7 0 0 7 7 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 NfI_DNAbd_pre-N PF10524.4 EMC79272.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus zf-C2H2 PF00096.21 EMC79273.1 - 3.1e-50 165.5 83.2 7.9e-07 29.0 0.8 10.7 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC79273.1 - 1.7e-35 119.5 73.2 3e-09 36.7 0.9 12.1 12 0 0 12 12 12 8 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC79273.1 - 2e-29 99.7 70.6 0.00028 20.9 0.8 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC79273.1 - 1.9e-16 59.3 67.4 0.0002 21.1 0.0 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79273.1 - 9.5e-13 47.8 56.0 0.0014 18.6 0.4 10.6 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EMC79273.1 - 2.6e-05 23.8 8.2 0.0001 22.0 0.7 8.2 4 3 4 8 8 8 3 BED zinc finger GAGA PF09237.6 EMC79273.1 - 0.0063 16.0 19.2 2.1 8.0 0.1 5.7 3 1 2 5 5 5 3 GAGA factor zf-met PF12874.2 EMC79273.1 - 0.31 11.3 48.1 0.56 10.4 0.2 9.5 9 0 0 9 9 9 0 Zinc-finger of C2H2 type BolA PF01722.13 EMC79273.1 - 0.48 10.4 4.4 55 3.8 0.0 4.9 3 3 2 5 5 5 0 BolA-like protein Reo_sigmaC PF04582.7 EMC79274.1 - 0.012 14.8 0.7 0.024 13.8 0.5 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Amdo_NSP PF12475.3 EMC79274.1 - 0.017 15.0 0.6 0.12 12.2 0.4 2.6 1 0 0 1 1 1 0 Amdovirus non-structural protein DUF948 PF06103.6 EMC79274.1 - 0.22 11.4 9.1 0.52 10.2 2.3 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4525 PF15027.1 EMC79274.1 - 0.29 10.6 5.9 0.044 13.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) LRR_4 PF12799.2 EMC79275.1 - 4.1e-10 39.0 8.0 0.0005 19.6 0.1 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79275.1 - 0.00025 20.7 6.0 0.02 14.6 0.7 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 EMC79275.1 - 0.00061 19.4 0.2 0.0013 18.3 0.1 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EMC79275.1 - 0.058 13.4 11.4 26 5.3 0.1 6.2 5 2 2 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.1 EMC79275.1 - 0.29 11.3 3.0 30 5.1 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 EMC79275.1 - 4.4 7.9 11.1 45 4.8 0.0 5.3 7 0 0 7 7 7 0 Leucine rich repeat Serpin PF00079.15 EMC79276.1 - 6.4e-120 400.6 2.9 7.2e-120 400.5 2.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.9 EMC79276.1 - 0.058 12.5 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DUF1241 PF06840.6 EMC79277.1 - 4.3e-66 220.9 4.4 6.1e-66 220.4 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Med11 PF10280.4 EMC79277.1 - 0.0012 18.9 1.8 0.004 17.1 0.4 2.2 1 1 1 2 2 2 1 Mediator complex protein FH2 PF02181.18 EMC79277.1 - 0.0042 16.0 2.6 0.0042 16.0 1.8 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain BLOC1_2 PF10046.4 EMC79277.1 - 0.0061 16.6 1.3 0.016 15.3 0.3 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.6 EMC79277.1 - 0.02 12.4 1.6 0.023 12.2 1.1 1.2 1 0 0 1 1 1 0 Prominin Decorin_bind PF02352.10 EMC79277.1 - 0.048 13.6 2.4 0.5 10.3 0.3 2.4 2 0 0 2 2 2 0 Decorin binding protein Hormone_1 PF00103.15 EMC79277.1 - 0.051 12.9 0.5 0.095 12.0 0.3 1.5 1 0 0 1 1 1 0 Somatotropin hormone family Sec23_trunk PF04811.10 EMC79277.1 - 0.082 12.2 1.3 1.1 8.5 0.2 2.6 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain DUF2852 PF11014.3 EMC79277.1 - 0.2 11.5 1.9 0.37 10.7 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4358 PF14270.1 EMC79277.1 - 0.29 11.0 3.2 11 5.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) Syntaxin_2 PF14523.1 EMC79277.1 - 1.2 9.2 5.7 1.6 8.8 3.1 1.9 1 1 0 1 1 1 0 Syntaxin-like protein KLRAQ PF10205.4 EMC79278.1 - 0.00073 19.5 4.3 0.00086 19.3 2.9 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein CENP-Q PF13094.1 EMC79278.1 - 0.0012 18.8 9.9 0.0017 18.4 6.9 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF342 PF03961.8 EMC79278.1 - 0.0059 15.0 1.1 0.0059 15.0 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) CALCOCO1 PF07888.6 EMC79278.1 - 0.0061 14.9 1.2 0.0061 14.9 0.8 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2987 PF11205.3 EMC79278.1 - 0.016 14.8 0.2 0.023 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) TMCO5 PF14992.1 EMC79278.1 - 0.018 14.2 3.4 0.02 14.0 2.3 1.1 1 0 0 1 1 1 0 TMCO5 family DUF3027 PF11228.3 EMC79278.1 - 0.026 14.2 0.2 0.029 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) Herpes_UL6 PF01763.11 EMC79278.1 - 0.031 12.4 3.4 0.032 12.4 2.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like YlqD PF11068.3 EMC79278.1 - 0.035 14.1 4.9 0.04 13.9 3.4 1.2 1 0 0 1 1 1 0 YlqD protein DUF972 PF06156.8 EMC79278.1 - 0.036 14.4 3.4 0.038 14.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EMC79278.1 - 0.038 14.4 1.1 0.056 13.8 0.8 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4482 PF14818.1 EMC79278.1 - 0.043 14.4 8.1 0.051 14.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Spc24 PF08286.6 EMC79278.1 - 0.049 13.3 3.4 0.06 13.0 2.3 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2207 PF09972.4 EMC79278.1 - 0.049 12.2 1.2 0.057 12.0 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phosducin PF02114.11 EMC79278.1 - 0.091 11.4 2.6 0.09 11.4 1.8 1.1 1 0 0 1 1 1 0 Phosducin TEX13 PF15186.1 EMC79278.1 - 0.095 12.2 2.4 0.12 11.9 1.7 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Atg14 PF10186.4 EMC79278.1 - 0.095 11.6 3.1 0.091 11.6 2.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OprD PF03573.8 EMC79278.1 - 0.096 11.4 0.8 0.19 10.4 0.5 1.6 1 1 0 1 1 1 0 outer membrane porin, OprD family V_ATPase_I PF01496.14 EMC79278.1 - 0.1 10.4 1.1 0.094 10.5 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HTH_37 PF13744.1 EMC79278.1 - 0.11 12.3 1.8 0.15 11.8 1.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DivIC PF04977.10 EMC79278.1 - 0.15 11.5 2.6 0.22 11.0 1.8 1.3 1 0 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 EMC79278.1 - 0.16 11.7 6.9 0.2 11.4 4.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Herpes_BLRF2 PF05812.7 EMC79278.1 - 0.23 11.2 7.7 0.32 10.8 5.3 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein OmpH PF03938.9 EMC79278.1 - 0.32 10.9 4.3 0.34 10.8 3.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3086 PF11285.3 EMC79278.1 - 0.53 9.0 3.3 0.62 8.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) IncA PF04156.9 EMC79278.1 - 0.79 9.2 4.6 0.94 9.0 3.2 1.1 1 0 0 1 1 1 0 IncA protein DUF3847 PF12958.2 EMC79278.1 - 1.8 8.3 11.3 2.5 7.9 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DUF2681 PF10883.3 EMC79278.1 - 2.7 8.2 6.4 3.8 7.7 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Cas6 PF09559.5 EMC79280.1 - 0.013 15.2 0.1 0.015 15.0 0.1 1.0 1 0 0 1 1 1 0 Cas6 Crispr zf-C2H2 PF00096.21 EMC79281.1 - 1.7e-17 62.5 66.2 0.0067 16.7 1.3 8.8 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79281.1 - 5.3e-17 60.8 61.9 0.0031 17.7 3.5 9.2 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79281.1 - 4e-06 26.7 27.6 0.012 15.7 0.5 6.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EMC79281.1 - 0.0013 18.9 5.8 0.005 17.0 1.0 10.5 11 0 0 11 11 11 5 Zinc-finger double domain PyrI_C PF02748.10 EMC79281.1 - 1.9 8.0 21.4 1.5 8.3 0.3 6.2 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.1 EMC79281.1 - 2.4 7.9 29.8 1.4 8.6 0.3 6.6 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EMC79281.1 - 8.7 6.1 29.9 0.95 9.2 0.8 7.2 7 0 0 7 7 7 0 BED zinc finger zf-CHCC PF10276.4 EMC79281.1 - 9.3 6.1 13.6 9.3 6.1 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger domain Podoplanin PF05808.6 EMC79282.1 - 1.4e-19 70.2 3.8 1.3e-17 63.7 2.6 2.0 1 1 0 1 1 1 1 Podoplanin Epiglycanin_C PF14654.1 EMC79282.1 - 0.67 9.9 2.9 0.77 9.7 1.5 1.5 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2668 PF10873.3 EMC79282.1 - 1.9 8.6 4.8 2.9 8.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) LRR_8 PF13855.1 EMC79283.1 - 1.8e-32 110.9 24.7 5.6e-13 48.4 2.6 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC79283.1 - 1e-18 66.4 13.1 1.1e-07 31.3 0.4 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC79283.1 - 2.2e-14 51.2 15.2 0.013 15.4 0.0 7.3 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_5 PF13306.1 EMC79283.1 - 1.1e-09 38.0 2.0 1.7e-09 37.4 0.0 2.1 1 1 1 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC79283.1 - 5.6e-06 25.7 14.8 0.33 11.3 0.2 6.5 6 0 0 6 6 6 2 Leucine rich repeat DUF3557 PF12078.3 EMC79283.1 - 0.0022 17.7 0.1 0.0056 16.3 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3557) LRR_9 PF14580.1 EMC79283.1 - 0.0082 15.7 2.4 0.2 11.1 0.9 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EMC79283.1 - 0.036 14.1 21.9 0.25 11.5 0.1 6.1 6 1 1 7 7 7 0 Leucine Rich repeat LRRNT PF01462.13 EMC79283.1 - 0.05 13.0 3.6 0.19 11.2 2.5 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_3 PF07725.7 EMC79283.1 - 1.7 8.5 9.0 17 5.4 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat Abhydrolase_3 PF07859.8 EMC79284.1 - 1e-58 198.4 0.1 5e-46 156.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EMC79284.1 - 4.6e-09 35.5 0.6 2e-08 33.4 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC79284.1 - 1.8e-05 24.5 0.1 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EMC79284.1 - 0.00017 20.3 0.0 0.00026 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EMC79284.1 - 0.027 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.7 EMC79284.1 - 0.16 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EMC79285.1 - 4.5e-50 170.1 0.0 2.8e-38 131.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC79285.1 - 0.00032 20.4 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMC79285.1 - 0.012 14.3 0.0 0.031 12.9 0.0 1.6 1 1 0 1 1 1 0 Carboxylesterase family DUF2920 PF11144.3 EMC79285.1 - 0.14 11.1 0.0 6.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.8 EMC79286.1 - 1.1e-48 165.5 0.0 5.2e-37 127.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC79286.1 - 5.4e-07 29.4 0.0 7.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMC79286.1 - 5.2e-05 22.1 0.1 0.00024 19.9 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMC79286.1 - 0.0023 17.1 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EMC79286.1 - 0.0083 14.6 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EMC79286.1 - 0.018 14.9 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TNFR_c6 PF00020.13 EMC79288.1 - 5.7e-13 48.6 50.3 6e-06 26.2 5.2 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 EMC79288.1 - 0.0014 18.1 2.0 0.0014 18.1 1.4 4.6 1 1 3 4 4 4 2 GCC2 and GCC3 Fzo_mitofusin PF04799.8 EMC79290.1 - 2.9e-83 277.4 1.0 2.9e-83 277.4 0.7 2.7 3 0 0 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.18 EMC79290.1 - 6.5e-24 84.6 1.1 2e-23 83.0 0.0 2.4 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EMC79290.1 - 1e-06 28.6 0.0 4.8e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Apolipoprotein PF01442.13 EMC79290.1 - 0.026 14.0 9.6 0.2 11.1 3.1 2.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain GTP_EFTU PF00009.22 EMC79290.1 - 0.093 12.1 0.5 0.65 9.4 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EMC79290.1 - 0.11 12.1 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain 2OG-FeII_Oxy PF03171.15 EMC79291.1 - 4.6e-09 36.4 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.9 EMC79291.1 - 4.8e-06 25.9 0.1 0.087 11.9 0.0 2.4 2 0 0 2 2 2 2 Anp1 Trypsin PF00089.21 EMC79292.1 - 1.1e-68 231.0 3.5 1.3e-68 230.8 2.5 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC79292.1 - 7.2e-06 25.4 0.1 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC79292.1 - 7.1e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Guanylate_cyc PF00211.15 EMC79293.1 - 9.9e-69 230.3 0.0 1.2e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 EMC79293.1 - 0.00046 19.4 0.8 0.00073 18.8 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated DUF4377 PF14302.1 EMC79293.1 - 0.03 14.2 0.1 0.1 12.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4377) ANP PF00212.13 EMC79295.1 - 2.1e-15 56.4 6.7 3.4e-15 55.8 4.6 1.3 1 0 0 1 1 1 1 Atrial natriuretic peptide ANP PF00212.13 EMC79296.1 - 1.5e-13 50.5 9.7 2.4e-13 49.9 6.7 1.3 1 0 0 1 1 1 1 Atrial natriuretic peptide Voltage_CLC PF00654.15 EMC79297.1 - 1.1e-95 320.6 23.8 3.4e-95 319.0 12.0 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EMC79297.1 - 4.9e-15 55.0 0.2 3.4e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain AGTRAP PF06396.6 EMC79298.1 - 2.3e-57 193.2 0.1 2.7e-57 192.9 0.1 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF2238 PF09997.4 EMC79298.1 - 0.54 9.6 3.0 0.47 9.8 0.8 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2238) Draxin PF15550.1 EMC79299.1 - 1.9e-141 471.4 11.8 2.2e-141 471.2 8.2 1.0 1 0 0 1 1 1 1 Draxin HORMA PF02301.13 EMC79300.1 - 4.2e-25 88.4 0.1 5.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 HORMA domain FBA PF04300.8 EMC79301.1 - 8e-79 263.8 0.9 1e-78 263.5 0.6 1.1 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.2 EMC79301.1 - 2e-13 49.8 5.6 5.7e-13 48.3 3.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC79301.1 - 2.2e-08 33.5 4.7 4.5e-08 32.5 3.3 1.6 1 0 0 1 1 1 1 F-box domain RS4NT PF08071.7 EMC79301.1 - 0.0049 16.6 0.3 0.013 15.3 0.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain FBA PF04300.8 EMC79302.1 - 1.5e-84 282.5 0.9 1.8e-84 282.2 0.7 1.1 1 0 0 1 1 1 1 F-box associated region F-box PF00646.28 EMC79302.1 - 6.2e-10 38.4 0.9 1.2e-09 37.6 0.6 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC79302.1 - 4.5e-07 29.5 1.6 1.1e-06 28.2 1.1 1.8 1 0 0 1 1 1 1 F-box-like UbiA PF01040.13 EMC79303.1 - 6.9e-39 133.6 15.8 8.9e-39 133.2 11.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Tom22 PF04281.8 EMC79303.1 - 0.22 11.0 0.5 2.2 7.8 0.0 2.4 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Fibrinogen_C PF00147.13 EMC79304.1 - 9.1e-70 234.8 8.9 1.3e-69 234.4 6.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain GldM_N PF12081.3 EMC79304.1 - 0.003 17.1 3.3 0.34 10.4 0.0 2.1 2 0 0 2 2 2 2 GldM N-terminal domain DUF4460 PF14687.1 EMC79304.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DNA_pol_A_exo1 PF01612.15 EMC79305.1 - 3.1e-49 166.8 2.1 5.6e-49 165.9 1.5 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EMC79305.1 - 2.7e-28 98.1 0.2 5e-27 94.0 0.0 2.8 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EMC79305.1 - 7.5e-14 51.2 0.0 2e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 HRDC domain DUF4230 PF14014.1 EMC79305.1 - 1.1 9.1 9.9 0.54 10.0 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4230) AATF-Che1 PF13339.1 EMC79305.1 - 1.4 9.0 17.0 43 4.2 8.7 3.7 3 1 1 4 4 4 0 Apoptosis antagonizing transcription factor Spermine_synth PF01564.12 EMC79306.1 - 2.1e-64 216.7 0.0 3e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EMC79306.1 - 7.4e-06 25.6 0.0 8.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC79306.1 - 0.0038 17.7 0.0 0.0071 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 EMC79306.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Somatostatin PF03002.10 EMC79307.1 - 4.9e-12 45.1 7.6 7.2e-12 44.6 5.3 1.3 1 0 0 1 1 1 1 Somatostatin/Cortistatin family CUB PF00431.15 EMC79308.1 - 1.1e-18 67.3 0.1 1.7e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 CUB domain FXa_inhibition PF14670.1 EMC79308.1 - 1e-07 31.9 9.7 1e-07 31.9 6.8 1.7 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 EMC79308.1 - 1.4e-07 31.3 7.9 2.9e-07 30.3 5.5 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.2 EMC79308.1 - 0.00066 19.2 5.4 0.00066 19.2 3.7 2.8 3 1 0 3 3 3 1 Complement Clr-like EGF-like EGF PF00008.22 EMC79308.1 - 0.0051 16.7 9.3 0.015 15.2 6.4 1.9 1 1 0 1 1 1 1 EGF-like domain CUB_2 PF02408.15 EMC79308.1 - 0.011 15.3 0.1 0.02 14.4 0.0 1.5 2 0 0 2 2 2 0 CUB-like domain EGF_MSP1_1 PF12946.2 EMC79308.1 - 4.6 7.1 7.2 7.8 6.3 3.5 2.2 1 1 1 2 2 2 0 MSP1 EGF domain 1 RRM_1 PF00076.17 EMC79309.1 - 2e-29 101.0 0.2 7.9e-17 60.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79309.1 - 3.3e-22 78.2 0.1 1.6e-10 40.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79309.1 - 5.7e-08 32.4 0.8 0.00097 18.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC79309.1 - 0.0004 20.1 0.0 0.057 13.2 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMC79309.1 - 0.084 12.6 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF240 PF03086.9 EMC79310.1 - 0.099 12.2 0.3 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 MG032/MG096/MG288 family 2 Pex14_N PF04695.8 EMC79311.1 - 2.1e-23 82.8 0.3 2.1e-23 82.8 0.2 3.9 2 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Nucleo_P87 PF07267.6 EMC79311.1 - 0.011 14.4 1.4 0.014 14.1 1.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF948 PF06103.6 EMC79311.1 - 0.021 14.6 1.4 0.045 13.5 0.9 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 EMC79311.1 - 0.21 10.6 1.9 0.35 9.8 1.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein CAF-1_p150 PF11600.3 EMC79311.1 - 0.52 9.6 10.5 1.2 8.5 7.2 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AATF-Che1 PF13339.1 EMC79311.1 - 2.8 8.0 8.2 0.71 10.0 1.1 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Ribosomal_60s PF00428.14 EMC79311.1 - 3.4 8.1 6.5 1.5 9.2 2.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DFF-C PF09033.5 EMC79312.1 - 2.4e-54 183.6 17.3 3.9e-54 182.8 7.6 2.1 2 0 0 2 2 2 2 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.10 EMC79312.1 - 3.6e-18 65.0 0.8 9e-17 60.6 0.0 3.0 3 0 0 3 3 3 1 CIDE-N domain T2SF PF00482.18 EMC79312.1 - 0.12 12.2 4.3 0.11 12.4 0.6 2.4 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Macoilin PF09726.4 EMC79312.1 - 1.9 6.7 15.9 0.34 9.1 5.2 2.0 1 1 1 2 2 2 0 Transmembrane protein FUSC-like PF12805.2 EMC79312.1 - 3.6 6.4 6.0 0.33 9.8 0.9 1.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS PSK_trans_fac PF07704.6 EMC79312.1 - 4.4 8.0 7.6 34 5.1 1.9 2.8 2 1 0 2 2 2 0 Rv0623-like transcription factor CENP-S PF15630.1 EMC79313.1 - 1.5e-08 34.6 0.2 3.1e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EMC79313.1 - 0.011 15.8 1.2 0.023 14.8 0.3 1.8 1 1 1 2 2 2 0 Core histone H2A/H2B/H3/H4 BLVR PF06375.6 EMC79313.1 - 0.02 14.7 3.7 0.021 14.6 2.6 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) HasA PF06438.7 EMC79313.1 - 0.023 14.1 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Heme-binding protein A (HasA) YihI PF04220.7 EMC79313.1 - 0.063 12.6 3.8 0.076 12.3 2.6 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) 6PGD PF00393.14 EMC79314.1 - 2.4e-135 450.4 0.0 2.7e-135 450.2 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain Kinesin PF00225.18 EMC79315.1 - 2.8e-117 391.1 0.5 4.6e-117 390.4 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EMC79315.1 - 1.7e-44 150.8 0.0 3.5e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EMC79315.1 - 2.4e-14 53.4 0.1 2.6e-13 50.0 0.0 2.9 3 0 0 3 3 3 1 PH domain KIF1B PF12423.3 EMC79315.1 - 1.3e-12 47.4 9.4 2.4e-10 40.2 0.0 3.4 3 0 0 3 3 3 2 Kinesin protein 1B FHA PF00498.21 EMC79315.1 - 5.2e-08 32.8 0.2 3.3e-07 30.3 0.1 2.5 2 0 0 2 2 2 1 FHA domain Ufd2P_core PF10408.4 EMC79316.1 - 2.3e-181 604.2 9.0 3.4e-181 603.7 6.3 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EMC79316.1 - 1.5e-07 31.2 0.6 4.5e-07 29.7 0.1 2.2 2 0 0 2 2 2 1 U-box domain CTP_transf_2 PF01467.21 EMC79317.1 - 2.3e-22 79.7 0.1 3e-22 79.3 0.1 1.5 1 1 0 1 1 1 1 Cytidylyltransferase Lipocalin PF00061.18 EMC79317.1 - 1.3e-12 47.8 0.7 2.1e-12 47.2 0.5 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family ICAT PF06384.6 EMC79318.1 - 4e-38 129.0 2.4 1.1e-37 127.6 0.1 2.3 2 1 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.6 EMC79318.1 - 0.00018 21.1 0.4 0.00025 20.6 0.3 1.3 1 0 0 1 1 1 1 CAMP factor (Cfa) DUF3313 PF11769.3 EMC79318.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) DUF892 PF05974.7 EMC79318.1 - 0.0042 16.9 2.5 0.0079 16.0 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF892) GvpG PF05120.7 EMC79318.1 - 0.0052 16.5 0.1 0.0052 16.5 0.1 2.4 2 0 0 2 2 2 1 Gas vesicle protein G ISG65-75 PF11727.3 EMC79318.1 - 0.012 14.6 1.3 0.018 14.1 0.9 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DMAP_binding PF06464.6 EMC79318.1 - 0.022 15.3 0.3 0.022 15.3 0.2 2.3 2 0 0 2 2 2 0 DMAP1-binding Domain Robl_LC7 PF03259.12 EMC79318.1 - 0.028 13.9 0.2 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain CK2S PF15011.1 EMC79318.1 - 0.046 13.5 6.2 0.86 9.3 0.0 2.5 2 1 1 3 3 2 0 Casein Kinase 2 substrate V_ATPase_I PF01496.14 EMC79318.1 - 0.05 11.4 2.2 0.054 11.3 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.6 EMC79318.1 - 0.072 10.6 0.9 0.095 10.2 0.6 1.2 1 0 0 1 1 1 0 Prominin NIT PF08376.5 EMC79318.1 - 0.073 12.5 0.5 0.073 12.5 0.3 2.1 1 1 1 2 2 2 0 Nitrate and nitrite sensing FlxA PF14282.1 EMC79318.1 - 0.084 12.8 10.3 0.075 12.9 5.2 2.1 1 1 1 2 2 2 0 FlxA-like protein WXG100 PF06013.7 EMC79318.1 - 0.098 12.6 0.5 0.098 12.6 0.4 2.4 3 0 0 3 3 2 0 Proteins of 100 residues with WXG EAP30 PF04157.11 EMC79318.1 - 0.16 11.1 5.5 0.28 10.3 3.5 1.6 1 1 0 1 1 1 0 EAP30/Vps36 family DUF4254 PF14063.1 EMC79318.1 - 0.19 11.3 3.4 0.31 10.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) GrpE PF01025.14 EMC79318.1 - 0.23 11.0 3.7 0.33 10.4 2.6 1.3 1 0 0 1 1 1 0 GrpE DUF1098 PF06497.6 EMC79318.1 - 0.25 11.4 2.3 0.25 11.4 0.8 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1098) Cauli_AT PF03233.8 EMC79318.1 - 0.3 10.7 3.1 0.58 9.8 2.2 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF148 PF02520.12 EMC79318.1 - 0.49 10.2 4.5 2.6 7.8 3.1 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF148 IncA PF04156.9 EMC79318.1 - 0.55 9.8 13.6 1 8.9 9.3 1.5 1 1 0 1 1 1 0 IncA protein Allexi_40kDa PF05549.6 EMC79318.1 - 0.56 9.4 3.8 0.8 8.9 2.1 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein Baculo_p24 PF05073.7 EMC79318.1 - 0.7 9.4 4.0 10 5.6 1.7 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein APG6 PF04111.7 EMC79318.1 - 0.72 8.8 6.9 0.85 8.6 4.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 EMC79318.1 - 0.87 9.3 7.4 2.2 8.0 0.9 2.7 2 1 1 3 3 3 0 Laminin Domain II DUF883 PF05957.8 EMC79318.1 - 0.95 9.9 4.3 2.5 8.5 0.9 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) NPV_P10 PF05531.7 EMC79318.1 - 1 9.6 5.3 1.2 9.4 2.4 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 EMC79318.1 - 2.6 7.9 4.9 21 5.0 2.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.13 EMC79318.1 - 5.1 6.0 7.7 6.9 5.6 4.5 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 EMC79318.1 - 5.5 7.4 8.1 7.9 6.9 3.4 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF342 PF03961.8 EMC79318.1 - 7.2 4.8 7.8 8.5 4.6 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) MerR-DNA-bind PF09278.6 EMC79318.1 - 9.2 6.7 10.3 0.45 10.9 1.9 2.6 3 0 0 3 3 2 0 MerR, DNA binding ICAT PF06384.6 EMC79319.1 - 2.3e-33 113.7 0.1 2.6e-33 113.6 0.1 1.0 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT DUF3140 PF11338.3 EMC79319.1 - 0.058 13.5 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Cadherin PF00028.12 EMC79320.1 - 2.8e-16 59.5 0.0 4.5e-08 33.2 0.0 2.8 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.1 EMC79320.1 - 1.6e-09 38.1 0.0 2.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EMC79320.1 - 0.0063 16.5 0.0 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 Laminin G domain Glyco_hydro_16 PF00722.16 EMC79320.1 - 0.011 15.0 0.2 0.033 13.4 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 16 PI3Ka PF00613.15 EMC79321.1 - 1.4e-56 190.5 2.8 2.6e-56 189.7 1.9 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EMC79321.1 - 2.6e-56 190.7 0.2 6.8e-56 189.3 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EMC79321.1 - 7.4e-34 116.5 0.0 2.4e-33 114.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 EMC79321.1 - 2.6e-24 85.2 0.1 9.9e-24 83.3 0.0 2.1 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain TpcC PF12642.2 EMC79321.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Conjugative transposon protein TcpC PI3K_p85B PF02192.11 EMC79322.1 - 7.7e-37 124.5 0.0 9.5e-37 124.2 0.0 1.1 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF918 PF06033.6 EMC79322.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) DUF2448 PF10476.4 EMC79323.1 - 7.7e-78 260.7 0.8 1.1e-77 260.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) Ima1_N PF09779.4 EMC79323.1 - 1.1e-36 126.1 11.7 2.4e-36 125.1 8.1 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1 PF03811.8 EMC79323.1 - 0.56 9.7 11.6 1.4 8.5 0.5 3.9 3 0 0 3 3 3 0 InsA N-terminal domain Mito_carr PF00153.22 EMC79324.1 - 3.6e-65 215.6 1.6 2.1e-21 75.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 7tm_2 PF00002.19 EMC79325.1 - 7.7e-12 44.8 11.3 1.1e-11 44.3 7.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EMC79325.1 - 7.3e-08 31.6 13.5 2.8e-07 29.7 9.4 1.7 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.12 EMC79325.1 - 0.01 14.6 7.5 0.12 11.1 5.2 2.1 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Sugar_tr PF00083.19 EMC79326.1 - 3.1e-127 424.8 27.9 3.6e-127 424.6 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC79326.1 - 1.5e-20 73.2 53.3 4.4e-18 65.1 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4027 PF13219.1 EMC79326.1 - 0.007 15.7 0.2 0.03 13.7 0.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4027) DUF2109 PF09882.4 EMC79326.1 - 0.89 9.5 8.8 7.1 6.6 4.7 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2109) Carb_anhydrase PF00194.16 EMC79327.1 - 2.2e-79 266.0 0.0 2.9e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pentaxin PF00354.12 EMC79327.1 - 8.5e-39 133.0 0.0 1.2e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 EMC79327.1 - 5.5e-11 42.9 0.5 8.7e-11 42.2 0.4 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily AhpC-TSA_2 PF13911.1 EMC79327.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Enolase_C PF00113.17 EMC79328.1 - 3.4e-161 535.1 0.0 4.3e-161 534.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EMC79328.1 - 1.1e-58 196.8 0.1 1.8e-58 196.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EMC79328.1 - 7.4e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EMC79328.1 - 0.00011 21.2 0.3 0.00025 20.0 0.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Noc2 PF03715.8 EMC79329.1 - 1.6e-114 381.7 7.6 1.6e-114 381.7 5.3 1.6 2 0 0 2 2 2 1 Noc2p family Kelch_1 PF01344.20 EMC79330.1 - 1.6e-76 251.6 10.8 3.9e-17 61.5 0.1 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EMC79330.1 - 8.4e-47 155.4 5.8 6.2e-10 38.8 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BACK PF07707.10 EMC79330.1 - 2.5e-36 123.6 0.1 5.2e-36 122.5 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 EMC79330.1 - 9.8e-36 121.3 4.5 1.4e-08 34.3 0.0 6.3 4 2 2 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 EMC79330.1 - 8.8e-34 115.8 0.7 1.4e-33 115.1 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 EMC79330.1 - 7.6e-31 105.5 12.8 4.1e-08 33.1 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC79330.1 - 4.6e-25 86.3 2.3 0.00011 21.7 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMC79330.1 - 8.2e-11 41.6 4.8 0.19 11.7 0.0 5.6 5 0 0 5 5 5 4 Kelch motif BA14K PF07886.6 EMC79330.1 - 0.044 13.4 0.7 1.8 8.3 0.0 3.6 4 0 0 4 4 4 0 BA14K-like protein PQQ_3 PF13570.1 EMC79330.1 - 0.93 9.8 10.8 20 5.6 0.0 5.6 6 0 0 6 6 6 0 PQQ-like domain Hairy_orange PF07527.8 EMC79334.1 - 1.6e-19 69.3 0.1 3.1e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.21 EMC79334.1 - 5.9e-15 54.7 2.2 3.5e-14 52.2 2.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nup35_RRM_2 PF14605.1 EMC79334.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Kazal_1 PF00050.16 EMC79335.1 - 1.5e-71 236.2 133.3 4.3e-12 45.8 3.2 10.5 10 1 0 10 10 10 8 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC79335.1 - 2.5e-71 235.3 81.5 8.6e-12 44.8 1.8 10.0 9 0 0 9 9 9 8 Kazal-type serine protease inhibitor domain NtA PF03146.10 EMC79335.1 - 6.3e-56 187.4 0.0 1.3e-55 186.4 0.0 1.6 1 0 0 1 1 1 1 Agrin NtA domain Laminin_G_1 PF00054.18 EMC79335.1 - 6.6e-21 74.6 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_EGF PF00053.19 EMC79335.1 - 7.5e-19 67.3 32.4 9.2e-13 47.9 8.1 14.2 9 4 5 14 14 14 2 Laminin EGF-like (Domains III and V) SEA PF01390.15 EMC79335.1 - 1.2e-15 57.0 0.0 2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 SEA domain Laminin_G_2 PF02210.19 EMC79335.1 - 9.7e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 EMC79335.1 - 6.7e-06 25.9 7.8 6.7e-06 25.9 5.4 10.5 9 1 0 9 9 9 1 EGF-like domain Y_phosphatase PF00102.22 EMC79336.1 - 7.6e-80 267.6 1.0 1.3e-79 266.9 0.2 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase SH2 PF00017.19 EMC79336.1 - 3.7e-52 174.0 0.0 4e-25 87.4 0.0 2.8 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.15 EMC79336.1 - 1.7e-05 24.4 0.0 6.5e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC79336.1 - 0.0013 18.8 3.8 0.002 18.2 0.0 2.7 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC79336.1 - 0.014 15.6 0.1 0.064 13.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family SIN1 PF05422.7 EMC79336.1 - 0.023 13.2 0.1 0.036 12.6 0.1 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) zf-RING_5 PF14634.1 EMC79337.1 - 2.2e-09 36.8 6.5 2.2e-09 36.8 4.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC79337.1 - 1.6e-07 31.0 6.8 1.6e-07 31.0 4.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC79337.1 - 7.7e-07 28.6 4.2 7.7e-07 28.6 2.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC79337.1 - 1.1e-06 28.2 3.6 1.4e-06 27.9 1.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EMC79337.1 - 2.8e-06 26.8 7.0 2.8e-06 26.8 4.9 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC79337.1 - 2.8e-06 27.2 7.1 2.8e-06 27.2 4.9 2.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC79337.1 - 1.6e-05 24.6 7.2 7.7e-05 22.4 5.0 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 EMC79337.1 - 0.061 13.1 0.3 0.097 12.5 0.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-rbx1 PF12678.2 EMC79337.1 - 0.78 9.8 8.1 0.24 11.5 2.9 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EMC79337.1 - 1.3 8.6 12.3 0.035 13.7 3.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EMC79337.1 - 2 7.9 7.9 13 5.4 5.2 2.5 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EMC79337.1 - 2.8 7.8 5.8 1.1 9.1 1.3 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4501 PF14946.1 EMC79338.1 - 4.1e-94 313.0 4.6 4.8e-94 312.8 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) SLR1-BP PF07333.7 EMC79338.1 - 0.08 13.1 6.5 0.13 12.4 4.5 1.3 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) GCC2_GCC3 PF07699.8 EMC79338.1 - 0.27 10.8 5.4 0.54 9.8 3.8 1.5 1 0 0 1 1 1 0 GCC2 and GCC3 UPF0560 PF10577.4 EMC79339.1 - 0.022 13.0 0.1 0.027 12.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NCD3G PF07562.9 EMC79339.1 - 1.1 8.9 22.2 0.39 10.4 1.8 3.0 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.13 EMC79340.1 - 4.4e-12 45.8 43.2 2.6e-06 27.3 6.4 3.7 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region TMEM154 PF15102.1 EMC79340.1 - 0.00019 21.1 0.1 0.00066 19.4 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family GCC2_GCC3 PF07699.8 EMC79340.1 - 1.4 8.5 26.4 0.045 13.3 1.5 3.8 2 1 1 3 3 3 0 GCC2 and GCC3 EF-hand_7 PF13499.1 EMC79341.1 - 1.4e-21 76.3 11.3 3.8e-08 33.3 0.1 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EMC79341.1 - 4.3e-21 72.5 7.7 0.00074 18.6 0.0 6.3 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.1 EMC79341.1 - 1.1e-14 52.8 1.2 0.062 13.2 0.0 5.9 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 EMC79341.1 - 1.3e-12 46.3 2.0 0.0016 17.6 0.0 5.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EMC79341.1 - 3.1e-08 33.0 5.9 0.012 15.1 0.0 5.7 5 1 1 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC79341.1 - 0.003 17.5 16.8 0.2 11.6 1.3 3.6 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region DsrC PF04358.8 EMC79341.1 - 0.022 14.9 0.9 0.13 12.4 0.1 2.5 2 1 0 2 2 2 0 DsrC like protein Pex14_N PF04695.8 EMC79341.1 - 0.038 14.0 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region C1q PF00386.16 EMC79342.1 - 7.9e-07 29.1 0.1 2.5e-06 27.5 0.0 1.9 2 1 0 2 2 2 1 C1q domain Collagen PF01391.13 EMC79342.1 - 0.0036 16.7 4.5 0.0057 16.1 3.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.13 EMC79342.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family UQ_con PF00179.21 EMC79343.1 - 2.3e-27 95.1 0.0 3.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ASC PF00858.19 EMC79344.1 - 8e-107 357.6 9.7 9.4e-107 357.3 6.8 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ArfGap PF01412.13 EMC79345.1 - 5.8e-42 142.1 0.5 1.8e-41 140.5 0.3 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EMC79345.1 - 2.1e-13 50.3 0.3 5.3e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.2 EMC79345.1 - 1.1e-11 44.9 1.3 5.5e-10 39.4 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC79345.1 - 1.5e-09 38.1 0.3 0.0033 17.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_11 PF15413.1 EMC79345.1 - 8e-08 32.5 0.7 3e-05 24.2 1.2 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain Ank PF00023.25 EMC79345.1 - 8.6e-07 28.4 1.6 0.0034 17.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMC79345.1 - 0.001 19.2 0.9 0.14 12.4 0.1 3.2 1 1 2 3 3 3 1 Ankyrin repeats (many copies) BAR PF03114.13 EMC79345.1 - 0.003 17.1 7.3 0.006 16.1 5.1 1.5 1 0 0 1 1 1 1 BAR domain Ank_3 PF13606.1 EMC79345.1 - 0.021 14.9 1.6 3.3 8.2 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Hepsin-SRCR PF09272.5 EMC79345.1 - 0.043 14.0 0.2 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Hepsin, SRCR PseudoU_synth_1 PF01416.15 EMC79346.1 - 3.8e-32 110.8 0.0 6.8e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Peptidase_C31 PF05410.8 EMC79346.1 - 0.019 14.7 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha 7tm_1 PF00001.16 EMC79347.1 - 2.5e-47 161.2 27.8 3.6e-47 160.6 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC79347.1 - 3.8e-07 30.0 8.7 3.8e-07 30.0 6.0 3.0 1 1 3 4 4 4 1 Olfactory receptor DUF2852 PF11014.3 EMC79347.1 - 0.088 12.7 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Beta-Casp PF10996.3 EMC79348.1 - 4.6e-28 97.6 0.0 1.5e-27 95.9 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EMC79348.1 - 6.2e-15 54.7 0.0 1.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EMC79348.1 - 7.9e-14 51.7 0.2 2.9e-13 49.9 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC79348.1 - 8.7e-11 41.7 1.3 5.4e-09 35.8 0.1 2.8 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC79348.1 - 4e-05 23.3 0.0 0.00031 20.4 0.0 2.4 3 1 0 3 3 3 1 Beta-lactamase superfamily domain GLTP PF08718.6 EMC79349.1 - 2.5e-34 118.4 0.0 3.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) V-set PF07686.12 EMC79350.1 - 5.4e-21 74.6 0.5 4.9e-11 42.5 0.0 2.6 1 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 EMC79350.1 - 6.2e-08 32.3 0.1 0.014 15.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC79350.1 - 2.9e-07 30.5 0.2 0.0039 17.2 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC79350.1 - 1.2e-06 28.5 0.1 0.071 13.2 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 EMC79350.1 - 2.5e-05 24.6 2.5 0.12 12.8 0.1 3.8 4 0 0 4 4 4 2 Immunoglobulin domain FixQ PF05545.6 EMC79350.1 - 0.00085 18.9 1.0 0.0017 17.9 0.7 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Receptor_2B4 PF11465.3 EMC79350.1 - 0.037 13.9 0.1 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 DUF347 PF03988.7 EMC79350.1 - 0.039 13.8 0.5 0.071 13.0 0.4 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) TMEM154 PF15102.1 EMC79350.1 - 0.062 13.0 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Lamp PF01299.12 EMC79350.1 - 0.63 9.1 4.0 3.7 6.5 1.1 2.2 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF1713 PF08213.6 EMC79351.1 - 3.7e-12 45.6 20.4 3.7e-12 45.6 14.2 1.9 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) PAD_N PF08526.5 EMC79351.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain ScpA_ScpB PF02616.9 EMC79351.1 - 0.37 10.3 2.9 0.53 9.8 2.0 1.1 1 0 0 1 1 1 0 ScpA/B protein adh_short PF00106.20 EMC79352.1 - 2.1e-18 66.7 0.1 3.3e-18 66.1 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC79352.1 - 6.6e-11 42.4 0.0 8.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC79352.1 - 2.4e-07 30.5 0.2 3.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMC79352.1 - 0.01 15.5 0.4 0.64 9.8 0.1 3.0 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 EMC79352.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Cyclin_N PF00134.18 EMC79353.1 - 2.1e-13 49.9 0.9 1.2e-07 31.3 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC79353.1 - 3.4e-06 26.9 0.1 3.4e-06 26.9 0.1 2.5 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 EMC79353.1 - 6.2e-05 22.7 0.4 0.11 12.3 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat E2F_TDP PF02319.15 EMC79353.1 - 0.0076 15.7 0.2 0.023 14.2 0.0 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DUF2779 PF11074.3 EMC79353.1 - 0.068 13.2 1.4 3.3 7.7 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) Ribosomal_L20 PF00453.13 EMC79354.1 - 4.6e-34 116.5 4.2 6.3e-34 116.1 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 DUF2852 PF11014.3 EMC79355.1 - 0.58 10.1 3.3 0.33 10.9 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) VWA PF00092.23 EMC79356.1 - 5.3e-36 123.9 0.0 8.9e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.16 EMC79356.1 - 2.6e-22 78.7 1.0 2.4e-10 40.4 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain VWA_2 PF13519.1 EMC79356.1 - 3.7e-14 53.2 0.0 5.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Interfer-bind PF09294.5 EMC79356.1 - 1.3e-05 25.2 0.0 0.0091 16.0 0.0 2.3 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Big_5 PF13205.1 EMC79356.1 - 0.0024 18.4 1.6 1.1 9.9 0.0 3.4 3 1 0 3 3 3 1 Bacterial Ig-like domain DUF1410 PF07198.6 EMC79356.1 - 0.036 14.3 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) DUF2369 PF10179.4 EMC79356.1 - 0.05 12.6 0.2 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) VWA_CoxE PF05762.9 EMC79356.1 - 0.096 11.8 0.1 0.4 9.7 0.1 1.9 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DUF3523 PF12037.3 EMC79357.1 - 4.7e-80 268.5 30.5 4.7e-80 268.5 21.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.24 EMC79357.1 - 9.8e-17 61.3 0.1 3.3e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC79357.1 - 8e-07 29.9 0.4 9.9e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMC79357.1 - 0.00018 20.6 0.0 0.00058 18.9 0.0 2.0 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EMC79357.1 - 0.00049 19.3 0.2 0.0036 16.5 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMC79357.1 - 0.00087 18.7 1.5 0.0012 18.3 0.0 1.9 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EMC79357.1 - 0.0018 17.7 0.1 0.014 14.8 0.0 2.5 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.1 EMC79357.1 - 0.0022 17.8 0.0 0.0022 17.8 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMC79357.1 - 0.0039 16.9 3.2 0.032 13.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMC79357.1 - 0.0099 16.0 7.3 0.041 14.0 0.0 3.5 2 2 1 3 3 2 1 AAA domain Zot PF05707.7 EMC79357.1 - 0.01 15.3 3.2 0.3 10.5 0.0 3.1 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EMC79357.1 - 0.015 15.0 0.0 0.057 13.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EMC79357.1 - 0.021 13.9 0.0 0.021 13.9 0.0 2.0 2 1 0 2 2 2 0 KaiC Ycf1 PF05758.7 EMC79357.1 - 0.022 12.4 4.0 0.027 12.1 2.8 1.1 1 0 0 1 1 1 0 Ycf1 AAA_24 PF13479.1 EMC79357.1 - 0.024 14.2 0.1 0.024 14.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMC79357.1 - 0.027 14.6 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EMC79357.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.5 2 2 1 3 3 2 0 AAA ATPase domain AAA_28 PF13521.1 EMC79357.1 - 0.37 10.7 0.0 0.37 10.7 0.0 3.3 3 1 1 4 4 3 0 AAA domain AAA_18 PF13238.1 EMC79357.1 - 0.52 10.6 0.1 0.52 10.6 0.1 2.6 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EMC79357.1 - 2.7 7.4 0.0 2.7 7.4 0.0 3.0 2 1 0 2 2 1 0 AAA domain TMEM240 PF15207.1 EMC79358.1 - 1.1e-61 207.6 2.0 1.2e-61 207.4 1.4 1.0 1 0 0 1 1 1 1 TMEM240 family DUF724 PF05266.9 EMC79361.1 - 2.9 7.4 32.7 0.089 12.4 8.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Pkinase PF00069.20 EMC79362.1 - 1.2e-58 198.3 0.0 1.2e-58 198.3 0.0 2.2 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79362.1 - 6.2e-28 97.5 0.5 1.6e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79362.1 - 5.8e-06 25.4 3.8 5.2e-05 22.3 0.0 2.8 2 1 0 3 3 3 2 Kinase-like Herpes_UL73 PF03554.8 EMC79363.1 - 4.2 7.2 10.1 0.17 11.7 0.5 3.2 3 0 0 3 3 3 0 UL73 viral envelope glycoprotein NAD_kinase PF01513.16 EMC79364.1 - 4.6e-63 212.6 0.1 5.9e-63 212.3 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EMC79364.1 - 0.11 11.8 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain zf-TRM13_CCCH PF11722.3 EMC79364.1 - 0.55 9.6 2.1 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein TMEM52 PF14979.1 EMC79366.1 - 6.5e-36 123.5 2.5 7.1e-36 123.4 1.7 1.0 1 0 0 1 1 1 1 Transmembrane 52 Shisa PF13908.1 EMC79366.1 - 0.035 14.2 0.2 0.041 14.0 0.1 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PapD-like PF14874.1 EMC79367.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Flagellar-associated PapD-like PapD-like PF14874.1 EMC79368.1 - 0.00014 21.7 0.0 0.81 9.6 0.0 2.7 2 0 0 2 2 2 2 Flagellar-associated PapD-like Neur_chan_LBD PF02931.18 EMC79369.1 - 4.2e-51 173.1 0.1 7.4e-51 172.3 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC79369.1 - 1.8e-40 139.3 6.5 2.2e-36 125.9 1.5 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 EMC79370.1 - 1.2e-61 208.1 0.0 1.7e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79370.1 - 2e-33 115.5 0.0 3.4e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 EMC79370.1 - 2.6e-16 59.0 0.0 5.5e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.17 EMC79370.1 - 3.7e-14 52.1 6.6 7.5e-14 51.2 4.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC79370.1 - 8.7e-07 29.3 0.7 1.7e-06 28.4 0.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC79370.1 - 1.1e-05 24.5 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC79370.1 - 0.011 14.7 0.0 0.03 13.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 EMC79370.1 - 0.17 11.9 1.3 0.52 10.3 0.9 1.9 1 0 0 1 1 1 0 C1-like domain Rer1 PF03248.8 EMC79372.1 - 9.2e-79 263.1 8.0 1.1e-78 262.9 5.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 EMC79372.1 - 0.81 8.8 4.5 0.1 11.8 0.3 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pex2_Pex12 PF04757.9 EMC79373.1 - 1.2e-36 126.3 2.8 1.4e-36 126.0 1.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EMC79373.1 - 4.7e-10 39.1 15.3 1e-09 38.0 10.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC79373.1 - 1.2e-09 37.9 14.0 2.2e-09 37.1 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC79373.1 - 4.3e-09 35.8 12.8 7.2e-09 35.1 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC79373.1 - 6.3e-08 32.1 13.8 1.2e-07 31.2 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC79373.1 - 8.7e-07 28.5 12.0 1.5e-06 27.8 8.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC79373.1 - 0.00049 19.7 7.5 0.0012 18.4 5.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMC79373.1 - 0.00053 20.0 10.8 0.0012 18.9 7.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger DUF3290 PF11694.3 EMC79373.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) zf-C3HC4_4 PF15227.1 EMC79373.1 - 0.0032 17.2 12.2 0.015 15.1 8.6 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EMC79373.1 - 0.0084 15.8 4.3 0.015 15.0 3.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Methyltrans_Mon PF14314.1 EMC79373.1 - 0.026 12.3 0.2 0.038 11.8 0.1 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase DUF3605 PF12239.3 EMC79373.1 - 0.027 14.2 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) zf-RING_4 PF14570.1 EMC79373.1 - 0.035 13.6 10.5 0.064 12.8 7.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1492 PF07374.6 EMC79373.1 - 0.075 13.1 0.1 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Prok-RING_4 PF14447.1 EMC79373.1 - 0.17 11.4 11.0 0.55 9.8 7.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EMC79373.1 - 0.29 10.9 6.8 0.61 9.9 4.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lig_chan PF00060.21 EMC79374.1 - 1.7e-40 138.1 0.4 2.8e-40 137.4 0.3 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 EMC79374.1 - 1.1e-20 73.8 0.0 1.6e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 EMC79374.1 - 5e-20 71.2 0.0 1.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF1795 PF08786.6 EMC79374.1 - 0.041 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) Fumble PF03630.9 EMC79375.1 - 2.9e-137 457.1 4.0 3.6e-137 456.7 2.8 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.14 EMC79375.1 - 7.4e-57 192.7 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 HLH PF00010.21 EMC79376.1 - 9.6e-10 38.0 0.4 1.5e-09 37.3 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC79376.1 - 9.7e-09 34.8 0.1 1.4e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.21 EMC79377.1 - 2.3e-14 52.8 1.7 4.7e-14 51.8 1.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC79377.1 - 0.00026 20.6 0.2 0.00053 19.6 0.1 1.5 1 0 0 1 1 1 1 Hairy Orange RNA_pol_Rpb4 PF03874.11 EMC79377.1 - 0.068 13.1 1.7 0.096 12.7 1.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 HLH PF00010.21 EMC79378.1 - 6.5e-15 54.5 2.0 1.1e-14 53.7 1.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC79378.1 - 2.7e-08 33.3 0.9 5e-08 32.5 0.6 1.4 1 0 0 1 1 1 1 Hairy Orange Translin PF01997.11 EMC79378.1 - 0.00062 19.4 0.6 0.00077 19.1 0.4 1.1 1 0 0 1 1 1 1 Translin family TNFR_c6 PF00020.13 EMC79379.1 - 1.4e-08 34.6 23.1 7.4e-07 29.1 5.5 3.1 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 EMC79379.1 - 0.013 15.0 20.2 0.17 11.4 5.1 2.7 2 2 0 2 2 2 0 GCC2 and GCC3 zf-C2H2 PF00096.21 EMC79382.1 - 7.7e-34 114.0 81.1 9.4e-07 28.8 0.8 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC79382.1 - 1.9e-20 72.0 69.6 3.5e-09 36.4 0.9 10.2 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC79382.1 - 5.7e-18 63.8 67.7 0.00033 20.7 0.8 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC79382.1 - 1.1e-08 34.6 64.8 0.017 15.0 0.3 8.7 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79382.1 - 1.4e-06 28.2 48.3 0.038 14.1 0.1 9.3 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EMC79382.1 - 3e-05 23.7 7.9 9.4e-05 22.0 0.6 7.8 4 2 4 8 8 8 2 BED zinc finger GAGA PF09237.6 EMC79382.1 - 1.6 8.3 21.4 2.2 7.9 0.3 5.3 4 1 2 6 6 6 0 GAGA factor RhoGEF PF00621.15 EMC79383.1 - 4.1e-37 127.8 1.9 5.7e-37 127.3 1.3 1.2 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.1 EMC79383.1 - 7.4e-13 47.8 0.4 2.7e-12 46.0 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC79383.1 - 1.3e-08 34.1 0.5 3.1e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMC79383.1 - 9.6e-08 31.4 0.0 2.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC79383.1 - 2.4e-06 27.7 0.0 7.5e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 PH domain hSac2 PF12456.3 EMC79385.1 - 7.9e-33 112.2 0.0 1.2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Inositol phosphatase WD40 PF00400.27 EMC79386.1 - 3.5e-12 45.7 5.3 0.00018 21.2 0.0 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.6 EMC79386.1 - 7.6e-08 32.2 0.2 0.23 11.1 0.0 4.3 2 2 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EMC79386.1 - 0.002 16.0 2.5 0.86 7.3 0.0 3.0 2 1 0 3 3 3 2 IKI3 family GFO_IDH_MocA_C PF02894.12 EMC79387.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Reo_sigmaC PF04582.7 EMC79388.1 - 0.00079 18.6 2.5 0.001 18.3 1.7 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Fez1 PF06818.10 EMC79388.1 - 0.0074 16.3 21.0 0.0074 16.3 14.5 1.4 1 1 0 1 1 1 1 Fez1 Lebercilin PF15619.1 EMC79388.1 - 0.024 14.0 20.9 0.044 13.1 14.5 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease LMP PF04778.7 EMC79388.1 - 0.059 13.1 4.5 0.18 11.5 3.0 1.8 1 1 1 2 2 2 0 LMP repeated region DUF2922 PF11148.3 EMC79388.1 - 0.073 12.7 0.2 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) SlyX PF04102.7 EMC79388.1 - 0.15 12.4 18.3 1.5 9.2 4.9 3.1 2 1 0 2 2 2 0 SlyX Prominin PF05478.6 EMC79388.1 - 0.31 8.5 10.2 0.38 8.2 7.1 1.0 1 0 0 1 1 1 0 Prominin IncA PF04156.9 EMC79388.1 - 1 8.9 32.7 0.36 10.4 20.5 1.8 1 1 0 2 2 2 0 IncA protein SLIDE PF09111.5 EMC79388.1 - 1.1 8.9 8.3 0.46 10.2 2.7 2.2 2 1 0 2 2 2 0 SLIDE Spc7 PF08317.6 EMC79388.1 - 1.6 7.3 19.5 1.4 7.4 12.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Rootletin PF15035.1 EMC79388.1 - 2.5 8.0 26.2 4.6 7.1 7.2 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion AA_kinase PF00696.23 EMC79388.1 - 4.3 6.8 6.7 1.1 8.6 1.4 1.9 1 1 1 2 2 2 0 Amino acid kinase family Spc24 PF08286.6 EMC79388.1 - 4.4 7.0 19.5 1 9.0 3.3 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 EMC79388.1 - 4.6 7.1 27.7 0.86 9.4 3.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EMC79388.1 - 5.1 6.6 22.1 23 4.5 0.2 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CDC37_N PF03234.9 EMC79388.1 - 5.6 7.2 15.6 5.7 7.2 10.4 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding CENP-F_leu_zip PF10473.4 EMC79388.1 - 6.4 6.6 28.8 1.8 8.4 16.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lge1 PF11488.3 EMC79388.1 - 7.3 6.8 17.5 0.25 11.5 4.1 2.9 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Phage_GP20 PF06810.6 EMC79388.1 - 7.7 5.9 14.5 33 3.8 3.3 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 AAA_13 PF13166.1 EMC79388.1 - 8.8 4.6 15.3 2.9 6.2 4.9 1.8 1 1 1 2 2 2 0 AAA domain Baculo_p24 PF05073.7 EMC79388.1 - 9.9 5.6 7.5 26 4.3 5.0 1.9 1 1 0 1 1 1 0 Baculovirus P24 capsid protein B3_4 PF03483.12 EMC79389.1 - 1.9e-09 37.1 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain LRR_4 PF12799.2 EMC79389.1 - 2e-05 24.0 0.0 0.0001 21.8 0.0 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79389.1 - 0.002 17.8 0.0 0.0067 16.1 0.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EMC79389.1 - 0.023 14.6 0.0 1.1 9.5 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EMC79389.1 - 0.044 13.9 0.5 1.2 9.5 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat DFF40 PF09230.5 EMC79390.1 - 1.5e-92 309.1 0.5 1.6e-92 309.0 0.4 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa AJAP1_PANP_C PF15298.1 EMC79392.1 - 2.5e-39 135.3 0.7 2.8e-39 135.1 0.5 1.0 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Aldo_ket_red PF00248.16 EMC79393.1 - 9.2e-69 231.3 0.0 1.1e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MRF_C1 PF13887.1 EMC79393.1 - 0.057 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Ribosomal_L22e PF01776.12 EMC79394.1 - 2.9e-41 139.9 2.2 3.2e-41 139.8 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family zf-RING_5 PF14634.1 EMC79395.1 - 0.00013 21.6 15.4 0.00013 21.6 10.7 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-B_box PF00643.19 EMC79395.1 - 0.00028 20.7 11.2 0.00028 20.7 7.8 3.9 4 0 0 4 4 4 1 B-box zinc finger MAD PF05557.8 EMC79395.1 - 0.00031 18.9 0.5 0.00031 18.9 0.3 1.8 2 0 0 2 2 2 1 Mitotic checkpoint protein zf-C3HC4 PF00097.20 EMC79395.1 - 0.00052 19.6 14.8 0.00052 19.6 10.3 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) IL10 PF00726.12 EMC79395.1 - 0.0033 16.7 2.6 0.0072 15.6 0.1 2.3 2 1 0 2 2 2 1 Interleukin 10 zf-RING_2 PF13639.1 EMC79395.1 - 0.01 15.6 15.9 0.01 15.6 11.0 3.4 3 0 0 3 3 3 0 Ring finger domain DUF3400 PF11880.3 EMC79395.1 - 0.053 12.7 0.3 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) AIP3 PF03915.8 EMC79395.1 - 0.21 10.4 7.3 0.021 13.7 1.5 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 KfrA_N PF11740.3 EMC79395.1 - 1.6 9.2 6.8 11 6.5 1.3 2.6 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term ICMT PF04140.9 EMC79396.1 - 1.1e-34 118.5 0.1 1.6e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EMC79396.1 - 4.4e-10 39.6 0.5 6.3e-10 39.1 0.4 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EMC79396.1 - 0.014 14.7 0.2 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) 4HBT PF03061.17 EMC79397.1 - 1.4e-24 85.9 1.0 2.5e-16 59.5 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.20 EMC79397.1 - 5.8e-05 22.8 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CARDB PF07705.6 EMC79397.1 - 0.033 14.2 0.2 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 CARDB IMCp PF12314.3 EMC79397.1 - 1.2 9.2 5.6 1.8 8.7 0.4 2.8 2 1 1 3 3 3 0 Inner membrane complex protein Clp1 PF06807.9 EMC79398.1 - 5.9e-44 150.1 0.0 9.2e-44 149.5 0.0 1.3 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ANF_receptor PF01094.23 EMC79399.1 - 2.4e-43 148.2 0.0 3e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EMC79399.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.17 EMC79399.1 - 0.0019 17.5 1.7 0.0031 16.9 1.2 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR zf-H2C2_2 PF13465.1 EMC79400.1 - 2.3e-44 147.5 68.2 8.1e-10 38.5 1.5 10.3 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79400.1 - 4.5e-35 117.8 62.9 1.1e-05 25.5 1.3 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79400.1 - 8.9e-26 88.3 59.2 0.00022 21.3 0.8 8.7 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79400.1 - 1.4e-11 44.1 35.5 0.004 17.2 0.4 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC79400.1 - 6.3e-11 42.0 34.4 0.04 14.1 0.7 7.7 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC79400.1 - 3.6e-08 33.3 37.9 0.00077 19.5 0.8 5.4 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EMC79400.1 - 5.9e-05 22.5 25.9 0.0081 15.7 0.4 5.1 2 1 4 6 6 6 3 GAGA factor zf-C2H2_6 PF13912.1 EMC79400.1 - 0.0004 20.1 47.5 0.031 14.1 0.3 8.3 8 0 0 8 8 8 3 C2H2-type zinc finger DUF2387 PF09526.5 EMC79400.1 - 0.011 15.6 0.5 0.011 15.6 0.4 4.3 3 1 1 4 4 4 0 Probable metal-binding protein (DUF2387) zf-C2H2_2 PF12756.2 EMC79400.1 - 0.015 15.3 44.6 0.075 13.1 5.3 7.2 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EMC79400.1 - 0.023 14.9 1.1 0.023 14.9 0.7 8.3 8 1 0 8 8 8 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 EMC79400.1 - 0.13 11.9 22.5 0.21 11.2 0.4 5.6 5 0 0 5 5 5 0 zinc-finger of a C2HC-type PhnA_Zn_Ribbon PF08274.7 EMC79400.1 - 0.69 9.7 0.1 0.69 9.7 0.0 4.5 6 0 0 6 6 5 0 PhnA Zinc-Ribbon Elf1 PF05129.8 EMC79400.1 - 2 8.1 35.2 0.16 11.6 0.9 5.9 2 2 5 7 7 7 0 Transcription elongation factor Elf1 like Rpr2 PF04032.11 EMC79400.1 - 5.2 7.0 24.7 0.19 11.5 0.4 3.8 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-FCS PF06467.9 EMC79400.1 - 7.6 6.2 26.0 5.2 6.7 0.3 6.0 6 1 1 7 7 7 0 MYM-type Zinc finger with FCS sequence motif Kelch_6 PF13964.1 EMC79401.1 - 3.4e-14 52.3 0.0 9.9e-10 38.1 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 EMC79401.1 - 8.2e-13 48.1 0.1 6e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EMC79401.1 - 9.1e-13 47.5 0.3 3.7e-08 32.7 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 EMC79401.1 - 9.8e-11 40.9 0.3 5.2e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 EMC79401.1 - 4.2e-09 36.0 0.2 1.8e-05 24.4 0.0 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC79401.1 - 0.0048 16.8 0.6 0.023 14.6 0.2 2.1 2 0 0 2 2 2 1 Kelch motif PFU PF09070.6 EMC79401.1 - 0.0078 16.2 0.0 0.1 12.6 0.0 2.1 1 1 1 2 2 2 1 PFU (PLAA family ubiquitin binding) PQQ_3 PF13570.1 EMC79401.1 - 0.078 13.2 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 PQQ-like domain PHD PF00628.24 EMC79402.1 - 1.4e-08 34.2 8.2 2.4e-08 33.5 5.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMC79402.1 - 8.5e-06 24.9 4.8 1.5e-05 24.2 3.3 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EMC79402.1 - 0.017 14.8 2.1 0.017 14.8 1.5 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDA1 PF10172.4 EMC79402.1 - 0.054 13.3 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase AfaD PF05775.7 EMC79402.1 - 0.077 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein zf-CW PF07496.10 EMC79402.1 - 0.15 11.7 3.4 0.39 10.4 2.4 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Autophagy_N PF03986.8 EMC79402.1 - 0.24 11.1 2.9 0.26 11.0 1.3 1.6 1 1 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF3268 PF11672.3 EMC79402.1 - 0.99 9.5 4.6 6 7.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Prok-RING_1 PF14446.1 EMC79402.1 - 1 9.1 6.5 0.14 11.8 1.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 EMC79402.1 - 1.2 9.3 5.0 19 5.4 0.1 2.4 2 0 0 2 2 2 0 C1 domain DUF3395 PF11875.3 EMC79403.1 - 4.2e-44 149.8 0.3 8.6e-44 148.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EMC79403.1 - 2.6e-07 30.2 0.3 1.1e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain Selenoprotein_S PF06936.6 EMC79403.1 - 0.049 13.1 0.2 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Selenoprotein S (SelS) Endonuclease_5 PF04493.9 EMC79403.1 - 0.11 11.8 0.4 0.16 11.2 0.3 1.3 1 0 0 1 1 1 0 Endonuclease V CG-1 PF03859.11 EMC79404.1 - 3.2e-56 187.9 1.8 3.2e-56 187.9 1.2 2.0 2 0 0 2 2 2 1 CG-1 domain Ank_2 PF12796.2 EMC79404.1 - 6.6e-09 35.9 0.1 9.3e-05 22.7 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) TIG PF01833.19 EMC79404.1 - 6.9e-09 35.5 0.2 6.9e-09 35.5 0.1 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.1 EMC79404.1 - 2.1e-06 27.7 0.5 0.12 12.6 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC79404.1 - 4.8e-06 26.0 1.7 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EMC79404.1 - 8e-05 22.5 0.2 0.71 10.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.22 EMC79404.1 - 0.0011 18.3 19.7 0.2 11.4 0.3 5.4 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ank_4 PF13637.1 EMC79404.1 - 0.0027 18.1 0.7 0.16 12.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Synaptobrevin PF00957.16 EMC79405.1 - 9.6e-36 121.2 4.1 1.1e-35 121.1 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF247 PF03140.10 EMC79405.1 - 0.027 13.5 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function Fijivirus_P9-2 PF06837.6 EMC79405.1 - 0.048 12.7 0.1 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein ERM PF00769.14 EMC79405.1 - 0.05 13.1 0.3 0.061 12.8 0.2 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ODV-E18 PF10717.4 EMC79405.1 - 0.066 12.6 0.2 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.6 EMC79405.1 - 5 6.6 7.7 6.5 6.2 5.0 1.4 1 1 0 1 1 1 0 African swine fever virus J13L protein Urotensin_II PF02083.10 EMC79406.1 - 1.3e-06 27.4 1.1 2.2e-06 26.6 0.8 1.4 1 0 0 1 1 1 1 Urotensin II DJ-1_PfpI PF01965.19 EMC79408.1 - 8.4e-34 116.1 0.0 1.1e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EMC79408.1 - 8.8e-16 57.6 0.0 1e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EMC79408.1 - 0.0097 15.5 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Inhibitor_Mig-6 PF11555.3 EMC79409.1 - 3.6e-25 88.1 11.2 3.6e-25 88.1 7.7 4.4 4 1 1 5 5 5 1 EGFR receptor inhibitor Mig-6 GTPase_binding PF09027.5 EMC79409.1 - 5.2e-24 83.6 0.0 1.3e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 GTPase binding Senescence_reg PF04520.8 EMC79409.1 - 0.082 13.3 0.9 0.21 12.0 0.6 1.7 1 0 0 1 1 1 0 Senescence regulator MFS_2 PF13347.1 EMC79410.1 - 2.7e-12 45.8 0.6 2.7e-12 45.8 0.4 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Hormone_2 PF00123.15 EMC79411.1 - 1.7e-14 53.3 0.2 2.5e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 Peptide hormone SAYSvFN PF10260.4 EMC79411.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Pkinase_Tyr PF07714.12 EMC79412.1 - 7.3e-94 313.6 0.0 9.2e-94 313.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC79412.1 - 4.3e-50 170.2 0.0 6.2e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC79412.1 - 1.2e-28 98.6 0.2 2.5e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC79412.1 - 8.9e-21 73.0 0.4 3.8e-20 71.0 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC79412.1 - 6.9e-16 57.5 0.0 1.8e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC79412.1 - 4.4e-12 45.3 0.0 1.2e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 EMC79412.1 - 0.011 15.4 0.0 0.064 12.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH3_3 PF08239.6 EMC79412.1 - 0.028 14.6 0.1 0.081 13.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain Thymidylat_synt PF00303.14 EMC79413.1 - 6.4e-112 372.9 0.0 7.1e-112 372.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Clusterin PF01093.12 EMC79414.1 - 7.8e-137 456.6 10.4 8.9e-137 456.4 7.2 1.0 1 0 0 1 1 1 1 Clusterin DUF1870 PF08965.5 EMC79414.1 - 0.07 12.7 0.2 0.32 10.6 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) Sulfatase_C PF14707.1 EMC79414.1 - 0.4 10.9 9.5 1.4 9.2 0.1 3.5 2 2 2 4 4 4 0 C-terminal region of aryl-sulfatase DUF3482 PF11981.3 EMC79414.1 - 1.3 8.1 3.7 2.8 7.0 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ARF7EP_C PF14949.1 EMC79414.1 - 3.6 8.0 12.3 8 6.9 0.4 2.4 2 0 0 2 2 2 0 ARF7 effector protein C-terminus efThoc1 PF11957.3 EMC79415.1 - 6.2e-154 513.1 6.5 8.8e-154 512.6 4.5 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.17 EMC79415.1 - 2e-18 65.9 2.6 4.2e-18 64.8 0.4 2.6 3 0 0 3 3 3 1 Death domain UCH PF00443.24 EMC79416.1 - 1e-58 198.5 0.5 1.2e-58 198.3 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC79416.1 - 7e-18 65.0 5.1 2e-17 63.5 3.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EMC79416.1 - 0.00043 19.6 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.1 EMC79416.1 - 0.014 14.6 1.3 0.16 11.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PFEMP PF03011.10 EMC79416.1 - 2.3 8.5 7.0 6.4 7.1 0.1 2.8 3 0 0 3 3 3 0 PFEMP DBL domain Pkinase PF00069.20 EMC79417.1 - 6.6e-61 205.7 0.0 6.6e-61 205.7 0.0 3.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79417.1 - 6.3e-30 104.0 0.6 2.1e-29 102.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.6 EMC79417.1 - 4.2e-24 84.6 14.5 4.2e-24 84.6 10.1 11.6 5 2 5 11 11 11 1 Rho Binding PH PF00169.24 EMC79417.1 - 2.2e-06 27.7 0.1 2.2e-06 27.7 0.1 3.6 3 2 0 3 3 3 1 PH domain Pkinase_C PF00433.19 EMC79417.1 - 3.7e-05 24.1 2.3 0.00011 22.6 1.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_1 PF00130.17 EMC79417.1 - 0.00051 19.7 5.9 0.0011 18.6 4.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 EMC79417.1 - 0.0012 18.6 0.2 0.011 15.5 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Myosin_tail_1 PF01576.14 EMC79417.1 - 0.24 9.0 170.2 0.27 8.8 50.4 5.0 1 1 3 4 4 4 0 Myosin tail LRR_8 PF13855.1 EMC79418.1 - 9.7e-61 201.4 66.1 3.1e-16 58.8 0.9 6.3 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 EMC79418.1 - 3.5e-24 83.9 29.6 1e-06 28.2 0.0 7.2 4 1 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC79418.1 - 7e-20 71.0 0.0 9.3e-09 35.0 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC79418.1 - 4.2e-16 56.5 33.3 0.18 11.9 0.0 12.4 12 0 0 12 12 12 4 Leucine Rich Repeat LRRNT PF01462.13 EMC79418.1 - 0.0022 17.4 1.5 0.0022 17.4 1.0 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 EMC79418.1 - 0.035 13.6 11.0 0.31 10.6 0.0 3.8 2 2 2 4 4 4 0 Leucine-rich repeat SWIM PF04434.12 EMC79418.1 - 0.79 9.2 5.5 7 6.2 0.1 3.1 3 0 0 3 3 3 0 SWIM zinc finger LRR_6 PF13516.1 EMC79418.1 - 1.2 9.4 30.1 1.3 9.3 0.0 9.7 10 1 1 11 11 11 0 Leucine Rich repeat LRR_7 PF13504.1 EMC79418.1 - 1.9 9.0 40.1 1.5 9.3 0.1 9.6 11 0 0 11 11 11 0 Leucine rich repeat Gag_spuma PF03276.9 EMC79418.1 - 4.6 5.4 8.0 6.4 4.9 5.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein COesterase PF00135.23 EMC79419.1 - 2.7e-185 617.1 0.0 3.2e-185 616.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family AChE_tetra PF08674.5 EMC79419.1 - 3.6e-19 68.0 5.8 3.6e-19 68.0 4.0 1.9 2 0 0 2 2 2 1 Acetylcholinesterase tetramerisation domain Abhydrolase_3 PF07859.8 EMC79419.1 - 8.5e-09 35.2 0.0 1.5e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold RRM_5 PF13893.1 EMC79420.1 - 3.1e-19 68.5 0.0 1.7e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79420.1 - 5e-15 55.2 0.1 5.5e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC79420.1 - 3.8e-12 45.6 0.2 0.00011 21.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC79420.1 - 8.1e-09 35.1 0.0 0.00025 20.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EMC79420.1 - 0.0018 17.8 2.5 0.0038 16.8 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 EMC79420.1 - 0.0027 17.7 0.3 0.0027 17.7 0.2 1.9 2 0 0 2 2 2 1 PWI domain RRM_3 PF08777.6 EMC79420.1 - 0.018 14.8 7.2 0.61 9.9 0.0 3.7 3 1 0 3 3 3 0 RNA binding motif RGS-like PF09128.6 EMC79420.1 - 0.07 12.6 0.1 0.07 12.6 0.1 2.8 2 1 0 2 2 2 0 Regulator of G protein signalling-like domain ApoO PF09769.4 EMC79422.1 - 3.2e-27 95.1 0.1 3.2e-27 95.1 0.1 1.8 2 0 0 2 2 2 1 Apolipoprotein O C2 PF00168.25 EMC79423.1 - 2e-41 139.6 0.1 2.6e-20 72.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 EMC79423.1 - 8.3e-08 32.1 6.3 1.8e-07 31.0 4.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C3HC4_3 PF13920.1 EMC79423.1 - 0.3 10.7 7.4 0.67 9.6 5.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 EMC79423.1 - 0.57 9.7 7.2 1 8.9 5.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Tetraspannin PF00335.15 EMC79424.1 - 5.2e-30 104.3 5.3 6e-30 104.1 3.7 1.0 1 0 0 1 1 1 1 Tetraspanin family FixQ PF05545.6 EMC79424.1 - 0.023 14.3 0.3 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ FeoB_C PF07664.7 EMC79424.1 - 0.044 13.1 3.1 0.08 12.3 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF4190 PF13828.1 EMC79424.1 - 0.054 13.0 3.8 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) OppC_N PF12911.2 EMC79424.1 - 0.39 10.1 1.5 3.1 7.2 0.3 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ABC2_membrane_4 PF12730.2 EMC79424.1 - 0.56 9.3 3.8 6.1 5.9 0.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF307 PF03733.8 EMC79424.1 - 1.1 9.7 4.4 1.2 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF307) BRICHOS PF04089.9 EMC79425.1 - 8.7e-19 67.1 0.0 1.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain RVT_1 PF00078.22 EMC79426.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CNH PF00780.17 EMC79427.1 - 5.1e-68 229.4 0.3 9.3e-68 228.6 0.2 1.4 1 0 0 1 1 1 1 CNH domain Rap_GAP PF02145.10 EMC79427.1 - 2.4e-63 212.9 0.0 4.4e-63 212.0 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Sugar_tr PF00083.19 EMC79429.1 - 1.5e-96 323.7 22.9 1.8e-96 323.4 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC79429.1 - 2.5e-31 108.6 27.7 2.5e-31 108.6 19.2 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC79429.1 - 7.8e-06 24.3 3.1 1.4e-05 23.5 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EMC79429.1 - 0.0049 15.6 8.9 0.23 10.1 6.2 2.2 1 1 0 1 1 1 1 BT1 family WD40 PF00400.27 EMC79430.1 - 2.5e-20 71.5 14.8 3.5e-08 33.0 0.0 6.7 7 2 0 7 7 7 4 WD domain, G-beta repeat F-box-like PF12937.2 EMC79430.1 - 3.4e-08 33.0 5.2 7.5e-08 31.9 2.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMC79430.1 - 1.1e-05 24.9 1.3 4.5e-05 22.9 0.5 2.3 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 EMC79430.1 - 0.065 11.3 6.8 1 7.4 0.3 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Glyco_transf_92 PF01697.22 EMC79431.1 - 4.6e-40 137.7 2.0 6.1e-40 137.3 1.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EMC79431.1 - 0.021 15.1 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 RasGEF PF00617.14 EMC79432.1 - 3.3e-54 183.4 1.7 5.5e-54 182.7 1.1 1.4 1 1 0 1 1 1 1 RasGEF domain PH PF00169.24 EMC79432.1 - 3.2e-07 30.4 0.0 6.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Fibrinogen_C PF00147.13 EMC79433.1 - 1.6e-76 257.0 12.1 2.2e-76 256.5 8.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2115 PF09888.4 EMC79433.1 - 0.0062 16.6 4.5 0.014 15.5 3.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2115) Fer4_NifH PF00142.13 EMC79433.1 - 0.015 14.5 1.5 0.029 13.5 1.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family BTB PF00651.26 EMC79434.1 - 2.7e-26 91.7 0.2 4.6e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 EMC79434.1 - 4e-15 55.1 22.8 3.3e-05 23.9 1.5 4.2 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC79434.1 - 9.9e-14 50.8 16.6 5.7e-07 29.5 0.4 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC79434.1 - 1.6e-12 46.8 12.7 0.00036 20.6 0.3 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMC79434.1 - 4.5e-08 33.0 8.3 0.0053 16.9 0.1 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC79434.1 - 7.9e-07 29.0 7.0 0.028 14.5 0.3 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF3342 PF11822.3 EMC79434.1 - 1.1e-06 28.0 2.7 1.6e-05 24.1 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) zf-BED PF02892.10 EMC79434.1 - 6.2e-05 22.6 15.7 0.11 12.2 0.4 3.5 2 1 1 3 3 3 3 BED zinc finger zf-C2H2_2 PF12756.2 EMC79434.1 - 0.0032 17.5 9.5 0.12 12.5 0.0 3.9 2 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) BIR PF00653.16 EMC79434.1 - 0.18 12.2 0.3 0.18 12.2 0.2 2.0 2 0 0 2 2 1 0 Inhibitor of Apoptosis domain DUF4187 PF13821.1 EMC79434.1 - 0.19 11.3 1.6 7 6.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) zf-C2HC_2 PF13913.1 EMC79434.1 - 1 9.0 11.3 4.7 7.0 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EMC79434.1 - 1.1 9.4 9.9 2.3 8.3 2.9 3.3 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 EMC79434.1 - 2.1 7.8 7.8 6.4 6.2 0.1 3.6 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-trcl PF13451.1 EMC79434.1 - 4.3 7.0 7.7 4.1 7.1 3.0 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain C1_1 PF00130.17 EMC79434.1 - 4.5 7.0 7.7 5 6.9 0.7 2.8 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BTB PF00651.26 EMC79435.1 - 2.5e-28 98.2 0.1 9.2e-19 67.4 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC79435.1 - 1.5e-10 40.7 17.2 7.4e-07 29.1 0.4 4.2 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79435.1 - 8e-10 38.4 24.1 0.0003 20.9 1.5 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79435.1 - 3e-07 30.3 16.2 0.035 14.4 0.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79435.1 - 0.32 11.1 14.7 5.2 7.3 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC79435.1 - 0.39 10.9 13.5 2.1 8.6 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type XPA_N PF01286.13 EMC79435.1 - 0.71 9.6 0.0 0.71 9.6 0.0 2.7 3 0 0 3 3 3 0 XPA protein N-terminal DUF968 PF06147.6 EMC79435.1 - 1.1 9.1 8.0 2.1 8.1 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF968) zf-C2H2_6 PF13912.1 EMC79435.1 - 2.2 8.3 15.8 0.99 9.4 0.1 4.5 5 0 0 5 5 5 0 C2H2-type zinc finger DUF2256 PF10013.4 EMC79435.1 - 4.2 7.2 8.2 0.37 10.5 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CSL PF05207.8 EMC79435.1 - 7.2 6.2 7.1 2.8 7.5 0.2 3.1 1 1 2 3 3 3 0 CSL zinc finger Homeobox PF00046.24 EMC79437.1 - 4.5e-18 64.6 2.3 9.7e-18 63.5 1.6 1.6 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 EMC79437.1 - 6.8e-17 61.2 11.3 1.1e-16 60.6 7.8 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.6 EMC79437.1 - 8.3e-05 22.2 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Pax7 PF12360.3 EMC79437.1 - 0.1 12.8 0.7 5 7.4 0.0 2.6 2 0 0 2 2 2 0 Paired box protein 7 YlqD PF11068.3 EMC79437.1 - 0.12 12.4 4.0 0.2 11.6 2.8 1.3 1 0 0 1 1 1 0 YlqD protein TLP-20 PF06088.6 EMC79437.1 - 0.17 11.5 0.8 0.5 10.0 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PBC PF03792.8 EMC79438.1 - 2.9e-72 242.3 4.0 4.3e-48 163.5 2.4 2.2 1 1 1 2 2 2 2 PBC domain Homeobox PF00046.24 EMC79438.1 - 2.1e-19 68.8 1.2 4.5e-19 67.8 0.9 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79438.1 - 3e-15 55.6 0.1 1.5e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Auxin_canalis PF05703.6 EMC79438.1 - 0.00066 19.5 0.6 0.0011 18.8 0.4 1.4 1 0 0 1 1 1 1 Auxin canalisation Homez PF11569.3 EMC79438.1 - 0.022 13.7 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sec15 PF04091.7 EMC79438.1 - 0.023 14.0 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF1319 PF07028.6 EMC79438.1 - 0.038 14.1 0.1 0.098 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) HTH_19 PF12844.2 EMC79438.1 - 0.044 13.8 0.1 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain IMD PF08397.6 EMC79438.1 - 0.081 12.2 2.8 0.098 11.9 1.3 1.6 2 0 0 2 2 2 0 IRSp53/MIM homology domain MADF_DNA_bdg PF10545.4 EMC79438.1 - 0.44 10.7 5.2 8.4 6.6 0.0 3.2 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SIN1 PF05422.7 EMC79439.1 - 1.6e-164 548.3 1.2 2e-164 547.9 0.8 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) Plasmodium_HRP PF05403.6 EMC79440.1 - 1.1e-07 31.6 32.8 0.0049 16.4 5.5 3.0 1 1 2 3 3 3 3 Plasmodium histidine-rich protein (HRPII/III) Collagen PF01391.13 EMC79440.1 - 0.002 17.6 41.7 1.3 8.6 5.2 4.2 1 1 3 4 4 4 2 Collagen triple helix repeat (20 copies) Extensin_2 PF04554.8 EMC79440.1 - 1.2 9.0 78.4 1.5e+04 -52.2 54.4 5.2 1 1 0 1 1 1 0 Extensin-like region RasGAP PF00616.14 EMC79441.1 - 3.3e-32 111.7 0.0 8.9e-32 110.3 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.13 EMC79441.1 - 6.3e-29 100.0 0.0 1.8e-28 98.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Motilin_assoc PF04643.7 EMC79441.1 - 0.1 12.1 3.1 14 5.2 0.0 3.6 3 0 0 3 3 3 0 Motilin/ghrelin-associated peptide HSP70 PF00012.15 EMC79442.1 - 2.1e-262 871.4 10.4 2.3e-262 871.2 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC79442.1 - 2.9e-17 62.2 0.1 6.3e-17 61.1 0.1 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EMC79442.1 - 3e-05 23.2 1.2 0.0013 17.9 0.1 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 EMC79442.1 - 0.0084 14.9 1.0 0.13 11.0 0.4 2.3 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EMC79442.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Kelch_3 PF13415.1 EMC79443.1 - 4.7e-30 103.0 10.0 3.1e-09 36.7 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC79443.1 - 2.8e-25 87.8 6.5 4.7e-09 35.8 0.0 4.7 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EMC79443.1 - 1.1e-22 79.2 0.2 3e-08 33.0 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EMC79443.1 - 4e-22 77.3 1.9 1.1e-07 31.6 0.0 3.7 2 1 2 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EMC79443.1 - 1.4e-19 69.6 7.6 2.8e-06 27.1 0.1 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EMC79443.1 - 9.2e-14 50.5 3.8 3.6e-05 23.3 0.0 4.3 4 1 0 4 4 4 3 Kelch motif PQQ_3 PF13570.1 EMC79443.1 - 0.0029 17.8 3.1 0.33 11.2 0.0 3.6 4 0 0 4 4 4 1 PQQ-like domain P16-Arc PF04699.9 EMC79444.1 - 7.7e-32 110.4 0.0 8.3e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 EMC79444.1 - 0.067 13.1 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family Ribosomal_L29 PF00831.18 EMC79445.1 - 9.6e-20 70.0 2.8 9.6e-20 70.0 1.9 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein XFP_N PF09364.5 EMC79445.1 - 0.091 11.2 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 XFP N-terminal domain Ribosomal_S9 PF00380.14 EMC79445.1 - 0.1 12.8 4.2 0.14 12.3 2.9 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 OmpH PF03938.9 EMC79445.1 - 3 7.7 7.7 8.6 6.2 5.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) OLF PF02191.11 EMC79446.1 - 7.4e-54 182.6 1.3 1.1e-53 182.1 0.9 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain zf-C4 PF00105.13 EMC79447.1 - 4e-28 97.4 17.9 7.7e-28 96.5 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC79447.1 - 8e-17 61.0 3.0 1.9e-16 59.8 2.1 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor 7tm_2 PF00002.19 EMC79448.1 - 1.5e-48 165.0 24.9 2.2e-48 164.4 17.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pentaxin PF00354.12 EMC79448.1 - 2.6e-29 102.0 0.1 4.9e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 EMC79448.1 - 9.1e-15 55.2 0.1 1.6e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.16 EMC79448.1 - 6.3e-10 38.9 10.6 9.9e-10 38.3 1.4 3.2 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain Dicty_CAR PF05462.6 EMC79448.1 - 3.8e-07 29.3 5.8 7.6e-07 28.3 4.0 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Tex_N PF09371.5 EMC79448.1 - 4.9e-05 22.7 0.5 9.8e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Tex-like protein N-terminal domain DUF3497 PF12003.3 EMC79448.1 - 0.00025 20.4 1.2 0.00043 19.6 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) Laminin_G_2 PF02210.19 EMC79448.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain Pox_P21 PF05313.7 EMC79448.1 - 7.9 5.6 12.3 0.13 11.5 1.4 2.4 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Proteasome PF00227.21 EMC79449.1 - 7.2e-46 155.8 0.0 9.8e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EMC79449.1 - 5.9e-15 54.2 0.2 1.6e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Pkinase PF00069.20 EMC79450.1 - 5.2e-66 222.4 0.0 6.4e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79450.1 - 2.1e-46 158.0 0.0 2.6e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79450.1 - 1e-05 24.6 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC79450.1 - 0.0083 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LIM PF00412.17 EMC79451.1 - 1.7e-31 108.0 20.9 1.1e-15 57.3 2.3 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 EMC79451.1 - 4.4e-19 67.8 3.5 8.3e-19 66.9 2.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79451.1 - 0.00026 20.6 1.2 0.00088 18.9 0.8 1.9 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC79451.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DENN PF02141.16 EMC79452.1 - 3e-47 160.7 1.8 5.4e-47 159.9 1.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EMC79452.1 - 4.7e-17 61.8 0.2 9.8e-17 60.7 0.2 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EMC79452.1 - 8.6e-16 57.6 1.5 2.1e-15 56.4 1.0 1.6 1 0 0 1 1 1 1 uDENN domain DZF PF07528.9 EMC79453.1 - 6.4e-80 268.1 0.0 1e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.20 EMC79453.1 - 9.7e-28 96.5 0.0 2.4e-14 53.6 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EMC79453.1 - 8.3e-07 29.2 0.3 0.11 12.8 0.0 3.4 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 BTB PF00651.26 EMC79454.1 - 4.1e-18 65.3 0.4 1.2e-17 63.8 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.21 EMC79454.1 - 5.2e-18 64.2 39.4 9.6e-06 25.6 1.8 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC79454.1 - 1.2e-17 63.2 23.6 1.8e-07 31.1 0.4 5.8 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC79454.1 - 8.7e-15 53.8 33.3 0.00028 21.0 0.5 5.1 5 0 0 5 5 4 4 C2H2-type zinc finger DUF899 PF05988.7 EMC79454.1 - 0.00047 19.6 1.3 0.00074 19.0 0.1 1.8 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF899) zf-C2H2_6 PF13912.1 EMC79454.1 - 0.00074 19.3 24.5 0.68 9.9 2.5 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 EMC79454.1 - 0.0025 17.9 25.1 0.034 14.3 1.9 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC79454.1 - 0.0027 17.7 19.1 0.35 11.0 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC79454.1 - 0.013 15.5 27.0 0.32 11.1 0.7 5.3 2 1 4 6 6 5 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EMC79454.1 - 0.082 12.3 4.1 1.1 8.7 0.0 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.4 EMC79454.1 - 0.16 11.7 0.1 0.16 11.7 0.0 2.9 4 0 0 4 4 4 0 Zinc-finger domain GAGA PF09237.6 EMC79454.1 - 0.36 10.4 8.3 23 4.7 0.0 4.2 1 1 3 4 4 4 0 GAGA factor zf-BED PF02892.10 EMC79454.1 - 3.7 7.3 26.8 4.9 6.9 2.0 4.4 2 2 2 4 4 4 0 BED zinc finger zf-LYAR PF08790.6 EMC79454.1 - 7.1 6.4 9.4 29 4.4 0.1 3.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FYVE PF01363.16 EMC79454.1 - 7.4 6.5 22.3 44 4.0 9.7 3.5 1 1 1 2 2 2 0 FYVE zinc finger C1_1 PF00130.17 EMC79454.1 - 8.3 6.2 17.6 28 4.5 0.2 3.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Phosducin PF02114.11 EMC79455.1 - 3.3e-135 448.9 3.3 4.1e-135 448.6 2.3 1.1 1 0 0 1 1 1 1 Phosducin WASH_WAHD PF11945.3 EMC79455.1 - 0.0033 16.7 0.6 0.005 16.1 0.4 1.3 1 0 0 1 1 1 1 WAHD domain of WASH complex DUF2267 PF10025.4 EMC79455.1 - 0.086 12.9 1.3 0.14 12.2 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) MRC1 PF09444.5 EMC79455.1 - 8.4 6.7 16.4 30 4.9 11.3 2.0 1 1 0 1 1 1 0 MRC1-like domain An_peroxidase PF03098.10 EMC79456.1 - 5.7e-84 282.4 0.0 2.3e-81 273.7 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase EGF PF00008.22 EMC79456.1 - 0.011 15.6 10.7 0.024 14.6 7.4 1.5 1 0 0 1 1 1 0 EGF-like domain PDGLE PF13190.1 EMC79456.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain RRF PF01765.14 EMC79457.1 - 2.1e-42 144.3 4.1 3e-42 143.8 2.9 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Robl_LC7 PF03259.12 EMC79457.1 - 0.065 12.8 0.0 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain DUF951 PF06107.6 EMC79457.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DUF883 PF05957.8 EMC79457.1 - 0.6 10.5 8.4 0.19 12.1 2.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EMC79457.1 - 4.8 7.6 6.5 4 7.8 2.4 2.1 2 0 0 2 2 2 0 YtxH-like protein RRM_5 PF13893.1 EMC79458.1 - 7.5e-13 48.1 0.1 1e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC79458.1 - 7.5e-12 44.7 0.1 1.2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79458.1 - 9.1e-09 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.3 EMC79458.1 - 0.1 12.8 1.8 0.15 12.2 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Homeobox PF00046.24 EMC79459.1 - 4.4e-20 71.0 1.8 7.6e-20 70.2 1.3 1.4 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 EMC79459.1 - 2.3e-16 59.5 11.6 1.1e-10 41.4 2.0 3.4 2 1 0 2 2 2 2 LIM domain Homeobox_KN PF05920.6 EMC79459.1 - 0.00041 19.9 0.1 0.00091 18.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain MRP-L20 PF12824.2 EMC79459.1 - 0.094 12.6 0.8 0.14 12.1 0.5 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Sgf11 PF08209.6 EMC79459.1 - 0.42 9.9 8.1 0.77 9.1 1.4 3.1 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF581 PF04570.9 EMC79459.1 - 0.6 9.4 11.3 3.5 6.9 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF581) DZR PF12773.2 EMC79459.1 - 0.61 9.9 10.8 0.11 12.3 1.0 2.9 2 1 0 2 2 2 0 Double zinc ribbon C1_3 PF07649.7 EMC79459.1 - 3.5 7.7 9.1 0.45 10.6 1.0 2.7 2 0 0 2 2 2 0 C1-like domain zf-C3HC4_3 PF13920.1 EMC79459.1 - 6.9 6.4 11.4 2.2 8.0 0.7 2.6 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 EMC79460.1 - 6.2e-12 44.5 8.9 1.5e-05 24.4 0.1 4.2 4 0 0 4 4 4 3 MORN repeat CHCH PF06747.8 EMC79461.1 - 1.4e-08 34.4 1.3 1.8e-08 34.1 0.9 1.2 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.12 EMC79461.1 - 0.048 13.6 1.9 0.063 13.2 1.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EMC79461.1 - 0.064 13.0 0.8 0.085 12.6 0.6 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EMC79461.1 - 0.16 11.9 1.9 0.63 10.0 0.1 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EMC79461.1 - 0.5 10.2 2.5 2.3 8.1 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) TTL PF03133.10 EMC79463.1 - 3e-19 69.0 0.0 5.3e-19 68.2 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMC79463.1 - 0.025 13.3 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp YajC PF02699.10 EMC79464.1 - 0.07 12.8 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Ribosomal_L5_C PF00673.16 EMC79466.1 - 2e-23 81.9 0.0 2.9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMC79466.1 - 6.9e-21 73.7 0.1 2.4e-19 68.8 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein L5 Palm_thioest PF02089.10 EMC79467.1 - 1.8e-149 496.2 0.0 2e-149 496.1 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase CAP_N PF01213.14 EMC79468.1 - 5.8e-118 393.7 0.0 7.8e-118 393.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EMC79468.1 - 4.6e-68 227.5 3.2 6.4e-68 227.1 2.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EMC79468.1 - 1.3e-05 24.6 1.7 2.2e-05 23.8 0.8 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor C WH2 PF02205.15 EMC79468.1 - 0.039 13.5 0.1 0.089 12.4 0.0 1.7 1 0 0 1 1 1 0 WH2 motif MFS_2 PF13347.1 EMC79469.1 - 2.5e-92 309.5 23.4 2.8e-92 309.3 16.3 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 EMC79469.1 - 5.9e-14 51.5 20.9 4.8e-13 48.5 14.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM154 PF15102.1 EMC79469.1 - 0.0054 16.4 0.0 0.071 12.8 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family EF-hand_1 PF00036.27 EMC79470.1 - 1.9e-17 61.1 5.3 1.2e-07 30.5 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EMC79470.1 - 1.1e-15 57.4 7.6 5.3e-11 42.5 0.8 2.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC79470.1 - 7.6e-15 53.4 2.1 3e-06 26.6 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EMC79470.1 - 2.3e-13 48.7 6.6 8.4e-06 24.8 0.2 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EMC79470.1 - 8.7e-08 31.6 4.5 0.0044 16.6 0.1 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EMC79470.1 - 0.0068 16.1 1.1 2.7 7.8 0.0 3.0 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC79470.1 - 0.019 15.0 0.7 5 7.2 0.0 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Homez PF11569.3 EMC79470.1 - 0.075 12.1 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez 5-nucleotidase PF06189.7 EMC79471.1 - 3.5e-114 380.0 0.0 2.2e-113 377.4 0.0 1.8 1 1 1 2 2 2 2 5'-nucleotidase RRM_1 PF00076.17 EMC79472.1 - 2.2e-91 299.5 3.2 4.6e-24 83.8 0.3 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79472.1 - 2.8e-63 209.8 1.6 1.6e-15 56.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79472.1 - 3.6e-46 154.8 0.1 2.1e-10 40.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EMC79472.1 - 6.5e-35 118.6 0.4 3.3e-34 116.3 0.4 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EMC79472.1 - 2.2e-09 36.9 2.5 0.03 14.0 0.1 4.3 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 EMC79472.1 - 3.5e-06 26.6 0.1 2.6 7.8 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EMC79472.1 - 0.0031 17.7 0.2 4.4 7.6 0.0 4.3 5 0 0 5 5 5 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 EMC79472.1 - 0.0066 15.9 3.2 2.1 7.9 0.1 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF3421 PF11901.3 EMC79472.1 - 0.049 13.3 0.1 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) Pro_isomerase PF00160.16 EMC79473.1 - 2.3e-46 157.8 0.4 3.5e-46 157.2 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EMC79473.1 - 1.4e-19 69.5 0.0 2.7e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79473.1 - 5.8e-14 51.8 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79473.1 - 3.6e-12 45.9 0.0 7.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spectrin PF00435.16 EMC79474.1 - 8.7e-154 501.6 161.5 6.3e-18 65.0 3.0 18.1 18 0 0 18 18 18 17 Spectrin repeat GAS2 PF02187.12 EMC79474.1 - 2.9e-39 132.6 0.9 6.5e-39 131.5 0.6 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.27 EMC79474.1 - 4.1e-13 47.6 2.2 2.2e-05 23.4 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC79474.1 - 8.8e-11 40.7 1.9 0.00025 20.6 0.3 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EMC79474.1 - 2.4e-10 40.3 1.6 1.5e-09 37.8 1.1 2.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC79474.1 - 1.8e-09 36.5 4.1 1.5e-05 24.1 1.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMC79474.1 - 1.8e-09 37.0 0.3 8.6e-09 34.8 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair zf-RING_3 PF14369.1 EMC79475.1 - 0.00034 20.5 2.8 0.0014 18.5 0.2 3.0 2 0 0 2 2 2 1 zinc-finger Rad50_zn_hook PF04423.9 EMC79475.1 - 0.38 10.2 4.6 0.21 11.1 0.2 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif RNA_pol_Rpc82 PF05645.8 EMC79476.1 - 1.5e-30 106.6 0.8 2.1e-27 96.3 0.0 3.2 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EMC79476.1 - 6.5e-24 83.5 3.7 5.6e-19 67.7 0.1 4.7 5 0 0 5 5 5 3 RNA polymerase III subunit RPC82 helix-turn-helix domain Mnd1 PF03962.10 EMC79476.1 - 0.016 14.8 3.2 0.054 13.1 2.2 1.8 1 0 0 1 1 1 0 Mnd1 family TFIIE_alpha PF02002.12 EMC79476.1 - 0.018 14.5 0.0 0.6 9.6 0.0 3.0 4 0 0 4 4 4 0 TFIIE alpha subunit Prominin PF05478.6 EMC79476.1 - 0.17 9.3 1.2 0.26 8.7 0.8 1.2 1 0 0 1 1 1 0 Prominin Peptidase_C1 PF00112.18 EMC79477.1 - 9e-40 136.8 0.0 9.6e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EMC79477.1 - 0.0025 16.4 0.3 0.0032 16.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase C1-like family DUF3606 PF12244.3 EMC79477.1 - 0.14 11.8 0.5 0.25 10.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Peptidase_C1 PF00112.18 EMC79478.1 - 2.3e-61 207.4 3.8 3.8e-46 157.7 0.2 2.1 1 1 1 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.7 EMC79478.1 - 4e-13 49.4 0.2 6.4e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EMC79478.1 - 5.6e-07 28.4 1.9 0.00027 19.6 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-C4H2 PF10146.4 EMC79479.1 - 0.0053 16.7 5.8 0.0078 16.2 4.0 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein P4Ha_N PF08336.6 EMC79479.1 - 0.016 15.0 5.0 0.075 12.8 1.3 2.4 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DOG1 PF14144.1 EMC79479.1 - 0.063 13.3 1.1 5.4 7.1 0.1 2.6 2 1 0 2 2 2 0 Seed dormancy control Cupin_8 PF13621.1 EMC79479.1 - 0.066 12.6 0.4 0.096 12.1 0.3 1.2 1 0 0 1 1 1 0 Cupin-like domain HisKA PF00512.20 EMC79479.1 - 0.2 11.6 3.6 1.8 8.6 0.0 2.9 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TMF_DNA_bd PF12329.3 EMC79479.1 - 0.21 11.3 11.1 0.15 11.9 4.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3461 PF11944.3 EMC79479.1 - 0.82 9.5 5.8 1.7 8.5 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) FlgN PF05130.7 EMC79479.1 - 0.95 9.7 8.7 1.2 9.3 4.6 1.9 2 0 0 2 2 2 0 FlgN protein Peptidase_C6 PF00851.13 EMC79479.1 - 1.6 7.3 5.6 1.1 7.8 2.7 1.5 1 1 0 1 1 1 0 Helper component proteinase TMPIT PF07851.8 EMC79479.1 - 1.9 7.5 4.6 0.8 8.7 1.2 1.7 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.7 EMC79479.1 - 4.9 6.9 6.1 11 5.7 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3837 PF12939.2 EMC79479.1 - 6.8 6.7 7.8 3.8 7.5 1.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3837) APG6 PF04111.7 EMC79479.1 - 7.3 5.5 11.1 12 4.8 6.9 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 DHHA2 PF02833.9 EMC79480.1 - 1.3e-13 51.2 0.0 5.4e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EMC79480.1 - 2.9e-08 33.4 0.0 1.4e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 DHH family PBD PF00786.23 EMC79481.1 - 0.00078 19.8 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain S_100 PF01023.14 EMC79482.1 - 6.7e-09 34.9 0.0 1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 EMC79482.1 - 9.3e-06 24.5 0.6 4.1e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMC79482.1 - 3.2e-05 23.9 1.6 9.3e-05 22.4 1.1 1.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC79482.1 - 0.00029 20.4 0.8 0.00066 19.3 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 EMC79482.1 - 0.0013 18.3 0.2 0.0017 18.0 0.2 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 EMC79482.1 - 0.013 15.0 0.2 0.085 12.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair S_100 PF01023.14 EMC79483.1 - 2.4e-21 74.7 0.8 3.3e-21 74.3 0.5 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 EMC79483.1 - 0.00023 21.2 0.2 0.0004 20.4 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC79483.1 - 0.0011 18.1 0.6 0.0042 16.3 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC79483.1 - 0.068 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain pair Keratin PF02422.11 EMC79487.1 - 1.4e-26 92.3 9.6 1.6e-26 92.1 6.7 1.1 1 0 0 1 1 1 1 Keratin Cornifin PF02389.10 EMC79487.1 - 0.0051 16.6 3.9 0.0059 16.4 2.7 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.3 EMC79487.1 - 0.016 15.1 4.7 0.035 14.1 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 EMC79488.1 - 1.5e-32 111.4 17.9 3.5e-32 110.2 12.4 1.7 1 1 0 1 1 1 1 Keratin Keratin PF02422.11 EMC79489.1 - 6.4e-32 109.4 22.0 4.2e-31 106.8 15.2 1.9 1 1 0 1 1 1 1 Keratin Keratin PF02422.11 EMC79490.1 - 1.9e-32 111.1 18.1 4e-32 110.0 12.6 1.6 1 1 0 1 1 1 1 Keratin Keratin PF02422.11 EMC79491.1 - 8.1e-39 131.5 11.2 8.7e-39 131.4 7.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC79493.1 - 3.3e-43 145.6 11.2 3.6e-43 145.4 7.8 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC79494.1 - 2.2e-46 155.7 10.7 2.4e-46 155.6 7.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC79495.1 - 2.2e-46 155.7 10.7 2.4e-46 155.6 7.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC79496.1 - 2.2e-46 155.7 10.7 2.4e-46 155.6 7.4 1.0 1 0 0 1 1 1 1 Keratin zf-C3HC4_3 PF13920.1 EMC79497.1 - 6.9e-07 28.8 9.1 6.9e-07 28.8 6.3 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC79497.1 - 3.8e-06 26.4 12.1 3.8e-06 26.4 8.4 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC79497.1 - 4.3e-05 23.4 13.4 4.3e-05 23.4 9.3 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC79497.1 - 7e-05 22.5 12.6 7e-05 22.5 8.7 3.9 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EMC79497.1 - 0.00013 21.5 10.1 0.00013 21.5 7.0 4.2 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC79497.1 - 0.0094 15.6 6.3 0.039 13.6 4.4 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EMC79497.1 - 0.28 10.9 19.4 0.13 12.0 2.8 3.2 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Yae1_N PF09811.4 EMC79498.1 - 1.8e-20 72.1 65.3 1.5e+04 -25.3 45.3 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Occludin_ELL PF07303.8 EMC79499.1 - 0.15 12.8 0.0 0.52 11.0 0.0 1.8 2 0 0 2 2 2 0 Occludin homology domain Pkinase PF00069.20 EMC79500.1 - 1.9e-73 246.7 0.0 3.3e-73 246.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79500.1 - 1.8e-34 119.0 0.0 3e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79500.1 - 0.041 12.8 0.1 1.9 7.3 0.0 2.2 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 EMC79500.1 - 0.28 10.8 1.7 2.3 7.8 0.1 2.7 2 1 0 3 3 3 0 Phosphotransferase enzyme family F5_F8_type_C PF00754.20 EMC79501.1 - 3.5e-32 110.9 0.8 5e-32 110.4 0.5 1.2 1 0 0 1 1 1 1 F5/8 type C domain Metallophos PF00149.23 EMC79502.1 - 1.1e-40 139.2 0.9 1.7e-40 138.6 0.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 EMC79502.1 - 2.3e-18 64.0 0.6 4.5e-05 22.4 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EMC79502.1 - 1.8e-15 56.8 0.4 1.8e-07 31.1 1.7 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC79502.1 - 3.9e-14 51.1 0.2 0.0037 17.0 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EMC79502.1 - 2.3e-11 43.1 0.1 0.0041 16.6 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC79502.1 - 6.3e-11 41.1 0.2 0.002 17.4 0.1 3.6 3 0 0 3 3 3 3 EF hand PPP5 PF08321.7 EMC79502.1 - 2.5e-08 33.8 0.0 5.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region IQ PF00612.22 EMC79502.1 - 0.11 12.2 0.8 0.24 11.1 0.5 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif EF-hand_4 PF12763.2 EMC79502.1 - 0.15 11.7 1.0 3.7 7.3 0.1 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Glyco_hydro_15 PF00723.16 EMC79503.1 - 5e-181 602.1 0.0 6e-181 601.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 E1_dh PF00676.15 EMC79504.1 - 7.7e-123 408.9 0.0 9.2e-123 408.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EMC79504.1 - 0.00082 18.9 0.3 0.0019 17.7 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EMC79504.1 - 0.0032 16.4 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF4071 PF13281.1 EMC79505.1 - 1e-159 531.4 0.4 1e-159 531.4 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.20 EMC79505.1 - 1.4e-63 214.4 0.0 2.7e-63 213.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79505.1 - 1.5e-41 142.1 0.0 2.7e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79505.1 - 0.00019 20.4 0.0 0.00064 18.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RE_Eco29kI PF09517.5 EMC79505.1 - 0.04 13.2 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Eco29kI restriction endonuclease SH3_9 PF14604.1 EMC79506.1 - 4.3e-35 119.0 1.1 1.8e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMC79506.1 - 1.9e-28 97.6 1.0 1.5e-13 49.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC79506.1 - 1.6e-27 94.5 1.9 4.9e-13 48.2 0.1 2.4 2 0 0 2 2 2 2 SH3 domain Tmemb_cc2 PF10267.4 EMC79506.1 - 0.00063 18.4 0.5 0.00099 17.8 0.4 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein XFP PF03894.10 EMC79506.1 - 0.0029 17.2 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase COG2 PF06148.6 EMC79506.1 - 0.24 11.2 4.2 0.41 10.5 2.9 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 EMC79506.1 - 1.3 7.9 5.8 2.4 7.0 4.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PDEase_I PF00233.14 EMC79507.1 - 4.4e-66 223.0 2.5 4.4e-66 223.0 1.8 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Histone_HNS PF00816.16 EMC79507.1 - 0.11 12.9 0.6 1.1 9.8 0.1 2.5 2 0 0 2 2 2 0 H-NS histone family WD40 PF00400.27 EMC79508.1 - 8.8e-12 44.4 2.5 3e-05 23.7 0.0 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat Hydrolase_6 PF13344.1 EMC79509.1 - 1.2 9.0 5.4 2 8.3 0.5 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeobox_KN PF05920.6 EMC79510.1 - 2.4e-19 68.7 0.8 4.6e-19 67.8 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC79510.1 - 3e-08 33.1 0.2 6.1e-08 32.1 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain TILa PF12714.2 EMC79511.1 - 0.01 15.6 4.9 0.01 15.6 3.4 4.2 2 1 3 5 5 5 2 TILa domain PALP PF00291.20 EMC79512.1 - 1.1e-58 198.8 0.0 1.4e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EMC79512.1 - 1.8e-05 24.4 0.0 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 1 CBS domain Poxvirus_B22R_C PF13168.1 EMC79512.1 - 0.0013 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus B22R protein C-terminal Integrase_Zn PF02022.14 EMC79512.1 - 0.16 11.4 0.4 4.2 6.9 0.1 2.5 2 0 0 2 2 2 0 Integrase Zinc binding domain zf-CCCH PF00642.19 EMC79513.1 - 2.4e-13 49.3 16.8 8.1e-07 28.5 2.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EMC79513.1 - 1.7e-08 34.1 0.0 3.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC79513.1 - 5.5e-07 29.1 0.0 9.1e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79513.1 - 0.00052 19.9 0.1 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) KMP11 PF03037.11 EMC79513.1 - 0.031 14.8 0.3 1.1 9.9 0.2 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 CART PF06373.6 EMC79513.1 - 0.046 13.6 1.8 0.51 10.3 0.3 2.8 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) Nup35_RRM_2 PF14605.1 EMC79513.1 - 0.047 13.4 0.2 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PRP38_assoc PF12871.2 EMC79513.1 - 8.4 6.9 34.1 17 6.0 23.6 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term HSP20 PF00011.16 EMC79514.1 - 1.2e-28 98.9 0.0 1.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 EMC79514.1 - 4e-26 90.9 1.4 7.3e-26 90.1 1.0 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal CCDC144C PF14915.1 EMC79515.1 - 0.00096 18.1 4.3 0.0018 17.2 3.0 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF972 PF06156.8 EMC79515.1 - 0.0014 18.9 2.7 0.0014 18.9 1.9 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF972) VHS PF00790.14 EMC79515.1 - 0.005 16.4 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 VHS domain HEAT PF02985.17 EMC79515.1 - 0.007 16.3 0.2 0.033 14.2 0.2 2.2 1 0 0 1 1 1 1 HEAT repeat Spc7 PF08317.6 EMC79515.1 - 0.011 14.3 6.7 0.02 13.5 4.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RasGEF_N_2 PF14663.1 EMC79515.1 - 0.013 15.4 0.0 0.053 13.4 0.0 2.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3584 PF12128.3 EMC79515.1 - 0.017 12.4 4.8 0.025 11.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EMC79515.1 - 0.03 13.3 6.8 0.058 12.4 4.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF732 PF05305.9 EMC79515.1 - 0.039 14.0 0.1 0.079 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF383 PF04063.9 EMC79515.1 - 0.071 12.6 2.3 0.16 11.5 1.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF383) Lectin_N PF03954.9 EMC79515.1 - 0.091 12.1 1.6 3 7.2 0.0 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Mnd1 PF03962.10 EMC79515.1 - 0.098 12.3 5.5 0.19 11.3 3.8 1.5 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 EMC79515.1 - 0.12 11.2 7.4 1.1 8.1 3.8 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1409 PF07197.7 EMC79515.1 - 0.15 12.1 7.2 0.048 13.7 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Remorin_C PF03763.8 EMC79515.1 - 0.2 11.2 4.0 0.36 10.3 2.8 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region TPR_MLP1_2 PF07926.7 EMC79515.1 - 3.5 7.3 13.7 0.056 13.1 4.1 2.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3782 PF12644.2 EMC79515.1 - 9.8 6.0 7.6 1.2 8.9 1.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) GrpE PF01025.14 EMC79515.1 - 10 5.6 9.4 20 4.7 6.0 1.7 1 1 0 1 1 1 0 GrpE Nop52 PF05997.7 EMC79516.1 - 9.8e-65 218.0 3.8 3.3e-64 216.3 2.6 1.9 1 0 0 1 1 1 1 Nucleolar protein,Nop52 PfkB PF00294.19 EMC79517.1 - 1.8e-33 115.9 0.1 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMC79517.1 - 2.8e-19 69.2 0.0 4.6e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HpcH_HpaI PF03328.9 EMC79517.1 - 0.0034 16.2 0.0 0.0075 15.1 0.0 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SDA1 PF05285.7 EMC79518.1 - 0.049 12.9 72.3 0.088 12.0 50.1 1.4 1 0 0 1 1 1 0 SDA1 GAGA_bind PF06217.7 EMC79518.1 - 0.45 10.4 18.5 1.1 9.2 12.8 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family CENP-T PF15511.1 EMC79518.1 - 5.8 6.0 52.8 14 4.7 36.6 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 EMC79518.1 - 9.4 5.1 64.9 22 3.9 45.0 1.5 1 0 0 1 1 1 0 BUD22 Acyltransferase PF01553.16 EMC79519.1 - 7.7e-14 51.2 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TRAPPC10 PF12584.3 EMC79521.1 - 3.4e-36 123.9 0.0 9.8e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 WD40 PF00400.27 EMC79522.1 - 3.3e-43 144.0 24.8 1.6e-12 46.7 0.1 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.7 EMC79522.1 - 3.3e-29 100.9 1.2 5.2e-29 100.3 0.8 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EMC79522.1 - 1.1e-07 31.8 0.9 0.36 10.5 0.0 5.0 4 2 2 6 6 6 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EMC79522.1 - 0.00035 20.1 0.1 0.41 10.3 0.0 4.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EMC79522.1 - 0.0048 16.6 0.2 7.5 6.2 0.0 4.3 5 1 1 6 6 6 1 Transcription factor IIIC subunit delta N-term DUF1513 PF07433.6 EMC79522.1 - 0.0052 15.7 0.0 0.061 12.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) Utp13 PF08625.6 EMC79522.1 - 0.014 15.0 0.9 0.048 13.3 0.6 2.0 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Kelch_6 PF13964.1 EMC79522.1 - 2.4 8.4 4.6 43 4.5 0.0 4.4 5 0 0 5 5 5 0 Kelch motif DJ-1_PfpI PF01965.19 EMC79523.1 - 9.7e-14 51.0 0.4 1.3e-13 50.6 0.3 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family V-set PF07686.12 EMC79524.1 - 4.9e-11 42.5 1.3 7.9e-10 38.6 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC79524.1 - 2.5e-10 40.1 0.2 1.2e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 EMC79524.1 - 4.9e-09 36.5 5.9 7.2e-05 23.2 1.6 3.7 2 2 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC79524.1 - 9.7e-09 35.2 1.9 0.00084 19.4 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC79524.1 - 2.4e-08 33.7 0.1 0.0091 15.8 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain C1-set PF07654.10 EMC79524.1 - 7.7e-07 29.0 1.7 5.7e-05 23.0 0.1 3.2 3 0 0 3 3 3 1 Immunoglobulin C1-set domain ig PF00047.20 EMC79524.1 - 3.7e-06 26.9 1.2 0.023 14.8 0.1 3.7 3 1 1 4 4 4 1 Immunoglobulin domain Lep_receptor_Ig PF06328.6 EMC79524.1 - 0.0021 17.9 1.1 0.11 12.3 0.1 3.0 2 1 0 2 2 2 1 Ig-like C2-type domain MLANA PF14991.1 EMC79524.1 - 0.0037 17.2 1.0 0.0085 16.1 0.5 1.7 1 1 0 1 1 1 1 Protein melan-A DUF2987 PF11205.3 EMC79524.1 - 0.027 14.1 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) DUF4328 PF14219.1 EMC79524.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF2207 PF09972.4 EMC79524.1 - 0.092 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FUN14 PF04930.10 EMC79526.1 - 1.8e-35 121.2 3.0 2.1e-35 120.9 2.1 1.1 1 0 0 1 1 1 1 FUN14 family DUF1126 PF06565.7 EMC79527.1 - 1.4e-26 91.6 0.1 7.8e-13 47.6 0.0 2.7 2 0 0 2 2 2 2 Repeat of unknown function (DUF1126) Cys_knot PF00007.17 EMC79528.1 - 2.5e-06 27.5 13.3 3.7e-06 26.9 9.2 1.3 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 EMC79528.1 - 3.4e-05 23.2 8.4 3.9e-05 23.0 5.8 1.1 1 0 0 1 1 1 1 DAN domain Amino_oxidase PF01593.19 EMC79529.1 - 5.1e-72 243.3 0.0 6e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC79529.1 - 1e-06 28.6 0.0 2.9e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC79529.1 - 0.001 18.0 0.0 0.41 9.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMC79530.1 - 1.7e-66 225.1 0.0 2e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC79530.1 - 6.3e-10 38.9 0.0 2.2e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC79530.1 - 0.0083 15.0 0.1 0.59 8.9 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMC79530.1 - 0.2 10.6 0.1 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain PSP1 PF04468.7 EMC79531.1 - 0.019 14.9 0.3 0.053 13.5 0.1 1.8 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Pkinase PF00069.20 EMC79532.1 - 3.8e-62 209.7 0.0 6.6e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Guanylate_kin PF00625.16 EMC79532.1 - 3.1e-60 202.7 0.1 5.6e-60 201.9 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.11 EMC79532.1 - 1.9e-34 117.0 8.2 3.2e-17 61.9 0.2 3.5 3 0 0 3 3 3 2 L27 domain Pkinase_Tyr PF07714.12 EMC79532.1 - 3.4e-27 95.1 0.0 5.7e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 EMC79532.1 - 8.1e-17 61.1 0.6 2e-16 59.9 0.4 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 EMC79532.1 - 2e-12 46.3 0.0 5.1e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC79532.1 - 2e-08 33.4 0.0 6.5e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC79532.1 - 2.2e-06 27.1 0.0 9.2e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ_2 PF13180.1 EMC79532.1 - 0.00091 19.0 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain LRR_8 PF13855.1 EMC79533.1 - 1.1e-67 223.6 36.6 1.4e-16 59.9 0.6 5.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EMC79533.1 - 1e-32 111.1 25.5 2.3e-07 30.2 1.0 6.6 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC79533.1 - 2.1e-23 78.7 25.5 0.065 13.2 0.0 11.4 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_5 PF13306.1 EMC79533.1 - 8.9e-21 73.9 0.3 3.6e-08 33.1 0.0 3.3 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC79533.1 - 2.7e-08 33.5 4.4 0.059 12.9 0.0 3.6 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 EMC79533.1 - 3.2e-06 26.4 27.0 4.5 7.9 1.3 10.4 11 0 0 11 11 11 2 Leucine rich repeat LRR_6 PF13516.1 EMC79533.1 - 5.3e-06 25.9 21.9 1.1 9.5 0.1 9.0 10 0 0 10 10 10 2 Leucine Rich repeat LRRNT PF01462.13 EMC79533.1 - 5.6e-06 25.6 6.5 1.1e-05 24.6 3.4 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Ribosomal_L2_C PF03947.13 EMC79534.1 - 2.1e-41 140.7 1.5 3e-41 140.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMC79534.1 - 1.4e-18 66.6 0.1 3.8e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain UCH PF00443.24 EMC79535.1 - 2.8e-60 203.7 0.6 7.7e-60 202.2 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC79535.1 - 1.1e-24 87.4 0.0 3.3e-19 69.4 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Med14 PF08638.6 EMC79536.1 - 1.4e-51 174.5 0.4 5.5e-51 172.5 0.0 2.2 2 0 0 2 2 2 1 Mediator complex subunit MED14 RE_SinI PF09570.5 EMC79536.1 - 0.028 13.4 0.0 0.064 12.2 0.0 1.5 1 0 0 1 1 1 0 SinI restriction endonuclease Armet PF10208.4 EMC79536.1 - 0.15 11.6 0.1 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Renin_r PF07850.9 EMC79537.1 - 9.1e-45 151.0 2.1 1.4e-44 150.4 1.5 1.3 1 0 0 1 1 1 1 Renin receptor-like protein Glycophorin_A PF01102.13 EMC79537.1 - 0.045 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Spot_14 PF07084.7 EMC79539.1 - 1.3e-57 194.1 0.0 1.5e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Tetraspannin PF00335.15 EMC79540.1 - 2.5e-48 164.2 11.6 3e-48 164.0 8.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Adeno_E3_CR2 PF02439.10 EMC79540.1 - 3.2 7.3 7.1 0.54 9.8 0.5 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF4229 PF14012.1 EMC79540.1 - 5.7 6.9 6.4 9.3 6.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) OTCace PF00185.19 EMC79541.1 - 6.1e-49 165.9 0.0 9e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EMC79541.1 - 6.1e-43 145.8 0.0 1.2e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CNTF PF01110.12 EMC79541.1 - 0.028 13.7 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Ciliary neurotrophic factor RCC1 PF00415.13 EMC79542.1 - 3.5e-69 228.8 17.1 3.3e-12 46.4 0.1 8.2 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC79542.1 - 2e-38 129.1 22.7 7.4e-09 34.9 0.1 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.1 EMC79542.1 - 0.0037 16.9 7.1 2.1 8.1 0.0 4.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC79542.1 - 0.005 16.5 0.1 6.3 6.7 0.0 3.4 3 0 0 3 3 3 2 Kelch motif DUF4174 PF13778.1 EMC79543.1 - 9.1e-28 96.7 0.0 1.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.11 EMC79543.1 - 1.5e-26 92.2 0.0 2.6e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 HYR domain Sushi PF00084.15 EMC79543.1 - 2e-25 88.9 25.0 1.5e-10 41.2 2.8 3.4 2 1 1 3 3 3 3 Sushi domain (SCR repeat) C2 PF00168.25 EMC79544.1 - 5.2e-42 141.5 0.6 2.9e-20 71.8 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 EMC79544.1 - 7.1e-18 64.6 10.0 1.2e-17 63.8 7.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-B_box PF00643.19 EMC79544.1 - 6.7 6.7 13.2 5.2 7.0 2.2 3.0 3 0 0 3 3 3 0 B-box zinc finger Tctex-1 PF03645.8 EMC79545.1 - 2.8e-35 120.2 2.1 3.3e-35 120.0 1.4 1.0 1 0 0 1 1 1 1 Tctex-1 family RE_SacI PF09566.5 EMC79545.1 - 0.0067 15.4 0.1 0.0075 15.2 0.0 1.1 1 0 0 1 1 1 1 SacI restriction endonuclease NAD_binding_6 PF08030.7 EMC79546.1 - 3.5e-37 127.7 0.0 5.6e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMC79546.1 - 8.4e-21 73.8 0.0 1.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMC79546.1 - 2.4e-20 72.8 5.6 2.4e-20 72.8 3.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMC79546.1 - 1.2e-06 28.5 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMC79546.1 - 0.0019 18.7 0.0 0.022 15.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain XK-related PF09815.4 EMC79547.1 - 1.8e-54 184.9 21.6 2.3e-54 184.6 15.0 1.1 1 0 0 1 1 1 1 XK-related protein Pox_polyA_pol PF03296.8 EMC79547.1 - 0.037 13.5 0.5 0.09 12.3 0.3 1.6 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain LANC_like PF05147.8 EMC79548.1 - 3.2e-59 200.2 0.0 4e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 EMC79548.1 - 0.0047 16.2 1.1 0.73 9.0 0.1 2.3 1 1 1 2 2 2 2 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 EMC79548.1 - 0.062 11.5 0.0 0.38 8.9 0.0 1.8 1 1 1 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Gla PF00594.15 EMC79549.1 - 6.5e-15 54.5 10.0 1.1e-14 53.8 6.9 1.3 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF4448 PF14610.1 EMC79549.1 - 0.021 14.2 0.0 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) GP41 PF00517.12 EMC79549.1 - 0.024 14.1 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Shisa PF13908.1 EMC79549.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 EMC79549.1 - 0.098 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF488 PF04343.8 EMC79549.1 - 0.12 12.7 0.6 0.19 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF488 P12 PF12669.2 EMC79549.1 - 0.8 9.9 3.7 1.7 8.8 2.6 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family RCR PF12273.3 EMC79549.1 - 1.1 9.8 4.1 1.8 9.1 0.8 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Motile_Sperm PF00635.21 EMC79550.1 - 2.6e-07 30.2 0.3 0.52 9.9 0.2 5.0 6 0 0 6 6 6 3 MSP (Major sperm protein) domain Gal-bind_lectin PF00337.17 EMC79551.1 - 0.0035 16.6 0.1 0.021 14.1 0.0 2.2 2 1 0 2 2 2 1 Galactoside-binding lectin CH PF00307.26 EMC79552.1 - 3.2e-07 30.3 0.2 1e-06 28.7 0.0 1.9 2 1 1 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC79552.1 - 0.0089 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain ArfGap PF01412.13 EMC79555.1 - 8e-41 138.4 0.0 1.9e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EMC79555.1 - 3.6e-15 56.0 0.1 7.2e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC79555.1 - 8.3e-13 47.4 1.1 3e-08 33.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMC79555.1 - 3e-10 40.0 0.7 1.4e-09 37.8 0.4 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC79555.1 - 3.3e-09 37.0 0.2 5.3e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH PF00169.24 EMC79555.1 - 8.6e-08 32.3 4.0 3e-07 30.5 0.7 2.9 2 1 0 2 2 2 1 PH domain Ank_3 PF13606.1 EMC79555.1 - 9.8e-07 28.4 0.0 3.8e-05 23.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PH_6 PF15406.1 EMC79555.1 - 0.0022 18.0 0.4 0.0022 18.0 0.3 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EMC79555.1 - 0.025 14.8 4.8 1 9.6 0.0 3.1 4 0 0 4 4 4 0 Pleckstrin homology domain Pap_E4 PF02711.9 EMC79555.1 - 0.033 15.0 2.3 0.82 10.5 0.3 2.8 2 0 0 2 2 2 0 E4 protein Chibby PF14645.1 EMC79555.1 - 0.047 13.5 0.7 0.1 12.4 0.5 1.5 1 0 0 1 1 1 0 Chibby family PH_8 PF15409.1 EMC79555.1 - 0.1 12.7 0.7 2.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Homeobox PF00046.24 EMC79556.1 - 2.5e-24 84.6 6.0 4.2e-24 83.9 4.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79556.1 - 0.07 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Ank_2 PF12796.2 EMC79557.1 - 7.8e-53 176.7 6.2 2.9e-18 65.9 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC79557.1 - 1.8e-30 103.2 19.2 6.8e-08 31.9 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EMC79557.1 - 7.5e-27 93.2 11.9 5.4e-08 33.1 0.2 6.9 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC79557.1 - 8.8e-25 86.1 13.4 2.5e-07 30.7 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC79557.1 - 3.3e-21 73.2 11.2 0.00039 20.4 0.0 7.0 8 0 0 8 8 8 4 Ankyrin repeat SOCS_box PF07525.11 EMC79557.1 - 1.7e-11 43.7 6.2 1.7e-11 43.7 4.3 2.2 2 0 0 2 2 2 1 SOCS box YjeF_N PF03853.10 EMC79557.1 - 0.16 11.5 0.5 0.81 9.2 0.2 2.0 1 1 1 2 2 2 0 YjeF-related protein N-terminus AAA PF00004.24 EMC79558.1 - 5.1e-17 62.3 0.0 1.2e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.22 EMC79558.1 - 1.2e-05 24.4 0.0 3.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Tox-HNH-HHH PF15637.1 EMC79558.1 - 0.057 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF630 PF04783.7 EMC79558.1 - 0.093 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF630) 7tm_1 PF00001.16 EMC79559.1 - 1e-53 182.1 24.8 1e-53 182.1 17.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) SH PF01445.12 EMC79559.1 - 0.1 12.2 0.2 0.1 12.2 0.2 2.5 3 0 0 3 3 3 0 Viral small hydrophobic protein PCI_Csn8 PF10075.4 EMC79560.1 - 6.8e-36 123.1 0.0 9e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EMC79560.1 - 0.0028 17.2 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EMC79560.1 - 0.018 15.3 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 PCI domain Rab_eff_C PF04698.7 EMC79561.1 - 3.9e-41 140.9 16.0 7.9e-41 139.9 11.1 1.4 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus FYVE_2 PF02318.11 EMC79561.1 - 2.3e-31 108.1 22.6 6.1e-21 74.5 2.5 3.5 2 1 1 3 3 3 2 FYVE-type zinc finger AATF-Che1 PF13339.1 EMC79561.1 - 0.17 12.0 10.4 1.2 9.2 0.2 2.9 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.1 EMC79561.1 - 0.19 10.6 10.4 0.35 9.8 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 EMC79561.1 - 4.9 6.8 11.3 28 4.4 1.9 3.8 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Prolactin_RP PF15172.1 EMC79562.1 - 5.5e-24 83.1 2.4 7.6e-24 82.6 1.7 1.2 1 0 0 1 1 1 1 Prolactin-releasing peptide LEAP-2 PF07359.6 EMC79562.1 - 0.092 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Ras PF00071.17 EMC79563.1 - 1.6e-54 183.6 0.1 1.9e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC79563.1 - 1.6e-19 70.5 0.0 3.1e-19 69.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC79563.1 - 3.4e-15 55.7 0.0 4.4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC79563.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC79563.1 - 0.00059 19.0 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC79563.1 - 0.0027 17.1 0.0 0.0071 15.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CPT PF07931.7 EMC79563.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FeoB_N PF02421.13 EMC79563.1 - 0.053 12.7 0.4 1.4 8.2 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2051 PF09738.4 EMC79564.1 - 4.5e-83 278.9 53.6 2.8e-55 187.7 15.7 4.3 2 1 1 3 3 3 2 Double stranded RNA binding protein (DUF2051) Seryl_tRNA_N PF02403.17 EMC79564.1 - 0.0064 16.4 7.2 0.0064 16.4 5.0 5.4 3 2 2 5 5 5 1 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 EMC79564.1 - 0.0075 16.0 56.2 0.32 10.7 9.2 4.2 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 EMC79564.1 - 0.018 12.4 44.8 0.018 12.4 14.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 EMC79564.1 - 0.021 14.4 59.5 0.1 12.1 9.9 4.0 1 1 3 4 4 4 0 IncA protein APG6 PF04111.7 EMC79564.1 - 0.027 13.5 57.1 1 8.3 8.6 4.0 1 1 2 4 4 4 0 Autophagy protein Apg6 Fib_alpha PF08702.5 EMC79564.1 - 0.039 14.0 37.3 0.09 12.8 8.3 4.1 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Tweety PF04906.8 EMC79564.1 - 0.06 11.7 17.5 0.2 10.0 2.2 3.9 2 2 3 5 5 5 0 Tweety DUF4509 PF14970.1 EMC79564.1 - 8.9 5.9 16.8 0.11 12.1 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) RRM_1 PF00076.17 EMC79566.1 - 2.2e-10 40.0 0.0 4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC79566.1 - 5.4e-10 39.1 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79566.1 - 8.4e-06 25.5 1.2 1.2e-05 24.9 0.2 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC79566.1 - 0.084 12.7 0.5 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif RAMP PF04901.8 EMC79567.1 - 3.5e-48 162.1 0.3 4e-48 161.9 0.2 1.0 1 0 0 1 1 1 1 Receptor activity modifying family UQ_con PF00179.21 EMC79568.1 - 1.3e-29 102.4 0.0 1.4e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC79568.1 - 0.00066 19.4 0.0 0.0009 18.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B IL28A PF15177.1 EMC79569.1 - 2.2e-18 66.2 0.1 2.3e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 Interleukin-28A Methyltransf_11 PF08241.7 EMC79570.1 - 1.9e-24 85.9 0.0 4.8e-24 84.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC79570.1 - 9.7e-16 57.7 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC79570.1 - 1.4e-13 50.8 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC79570.1 - 2.7e-13 49.5 0.0 4.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMC79570.1 - 5.7e-13 49.0 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC79570.1 - 4e-11 43.2 0.0 8.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC79570.1 - 2.6e-10 40.8 0.0 4.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC79570.1 - 6.7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMC79570.1 - 2.9e-07 30.3 0.0 7.4e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.6 EMC79570.1 - 2.8e-05 23.6 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.11 EMC79570.1 - 0.00014 20.3 0.0 0.00018 20.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EMC79570.1 - 0.00033 19.8 0.0 0.00073 18.6 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EMC79570.1 - 0.00048 19.5 0.0 0.0017 17.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.13 EMC79570.1 - 0.00097 18.6 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 DNA methylase tRNA_U5-meth_tr PF05958.6 EMC79570.1 - 0.0039 15.9 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DUF938 PF06080.7 EMC79570.1 - 0.0052 16.3 0.0 0.016 14.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.8 EMC79570.1 - 0.0054 15.8 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EMC79570.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC79570.1 - 0.0099 14.9 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase DREV PF05219.7 EMC79570.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 EMC79570.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EMC79570.1 - 0.037 14.0 0.0 0.26 11.2 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.5 EMC79570.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase COG5 PF10392.4 EMC79571.1 - 0.032 14.1 0.3 0.047 13.6 0.2 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 fn3 PF00041.16 EMC79572.1 - 1.5e-264 855.0 83.8 1.3e-20 73.3 0.6 17.3 17 0 0 17 17 17 17 Fibronectin type III domain fn1 PF00039.13 EMC79572.1 - 3.2e-151 490.8 165.3 1.7e-14 53.3 2.1 12.7 12 0 0 12 12 12 12 Fibronectin type I domain fn2 PF00040.14 EMC79572.1 - 6.2e-35 118.9 19.3 1.4e-17 63.3 4.3 3.3 2 0 0 2 2 2 2 Fibronectin type II domain Interfer-bind PF09294.5 EMC79572.1 - 7.4e-17 61.3 0.5 1 9.4 0.0 12.5 14 0 0 14 14 14 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.4 EMC79572.1 - 3.8e-09 36.0 19.2 0.033 13.3 0.1 11.1 12 1 1 13 13 13 3 Uncharacterised conserved protein (DUF2369) DUF1410 PF07198.6 EMC79572.1 - 0.0016 18.7 5.5 28 5.1 0.0 7.5 9 0 0 9 9 9 0 Protein of unknown function (DUF1410) DUF2012 PF09430.5 EMC79572.1 - 0.05 13.4 0.6 13 5.6 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2012) fn3_3 PF14686.1 EMC79572.1 - 0.066 13.3 3.3 13 5.9 0.1 4.4 5 0 0 5 5 5 0 Polysaccharide lyase family 4, domain II Glyco_hydro_66 PF13199.1 EMC79572.1 - 0.12 10.7 6.4 8.2 4.6 0.0 5.3 6 0 0 6 6 6 0 Glycosyl hydrolase family 66 SusE PF14292.1 EMC79572.1 - 2.6 7.8 17.1 1.1e+02 2.6 0.0 8.5 10 0 0 10 10 10 0 SusE outer membrane protein ABC_tran PF00005.22 EMC79574.1 - 6.9e-30 104.1 0.0 9.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC79574.1 - 2.9e-13 50.4 0.5 1.7e-11 44.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EMC79574.1 - 7.6e-06 25.2 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EMC79574.1 - 0.00086 19.6 1.0 0.0012 19.1 0.7 1.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EMC79574.1 - 0.0012 18.1 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMC79574.1 - 0.0046 16.4 0.5 0.0089 15.5 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMC79574.1 - 0.027 14.3 0.0 0.3 11.0 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF1846 PF08903.6 EMC79574.1 - 0.045 12.2 0.0 0.062 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) SRP54 PF00448.17 EMC79574.1 - 0.058 12.8 0.2 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EMC79574.1 - 0.073 13.2 0.3 0.3 11.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EMC79574.1 - 0.078 11.4 0.2 2.8 6.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain VWC PF00093.13 EMC79576.1 - 4.5e-09 36.2 52.4 7.2e-06 26.0 11.9 3.2 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.8 EMC79576.1 - 0.0014 18.1 5.1 0.0014 18.1 3.5 3.9 3 0 0 3 3 3 2 Pacifastin inhibitor (LCMII) DUF2205 PF10224.4 EMC79577.1 - 0.18 11.4 8.1 1 9.0 0.0 3.5 3 1 0 4 4 4 0 Predicted coiled-coil protein (DUF2205) APG6 PF04111.7 EMC79577.1 - 0.27 10.2 5.6 0.34 9.8 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 EMC79577.1 - 3.3 7.7 8.4 1.1 9.2 0.8 3.0 3 1 1 4 4 4 0 bZIP transcription factor zf-H2C2_2 PF13465.1 EMC79578.1 - 2.4e-19 68.5 34.0 2e-08 34.0 1.9 7.5 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79578.1 - 1.6e-15 56.3 43.8 0.00014 21.9 0.9 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79578.1 - 1.7e-09 37.3 42.0 0.0015 18.7 0.6 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger GAGA PF09237.6 EMC79578.1 - 0.002 17.6 3.7 0.15 11.6 0.1 3.2 2 1 1 3 3 3 2 GAGA factor zf-C2H2_jaz PF12171.3 EMC79578.1 - 0.0034 17.4 24.7 0.68 10.1 0.3 6.8 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-MYND PF01753.13 EMC79578.1 - 0.017 14.9 7.5 0.2 11.5 0.0 3.5 3 1 0 3 3 3 0 MYND finger zf-H2C2_5 PF13909.1 EMC79578.1 - 0.054 13.7 1.0 0.054 13.7 0.7 6.0 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-met PF12874.2 EMC79578.1 - 0.13 12.5 0.2 0.13 12.5 0.1 6.5 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EMC79578.1 - 0.52 10.7 15.2 0.25 11.7 2.6 3.7 3 0 0 3 3 3 0 TRAF-type zinc finger GATA PF00320.22 EMC79578.1 - 2.5 7.5 9.5 10 5.5 0.1 4.0 4 0 0 4 4 4 0 GATA zinc finger zf-CHCC PF10276.4 EMC79578.1 - 9.4 6.1 11.3 0.48 10.3 0.3 3.3 4 0 0 4 4 4 0 Zinc-finger domain Pkinase_Tyr PF07714.12 EMC79579.1 - 1.6e-91 305.9 0.0 2.9e-91 305.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 EMC79579.1 - 9.5e-58 193.0 4.6 5e-30 103.7 0.2 2.5 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.1 EMC79579.1 - 4.5e-53 178.3 82.8 1.9e-47 160.1 20.1 3.9 2 1 1 3 3 3 3 Growth factor receptor domain IV Pkinase PF00069.20 EMC79579.1 - 1.1e-41 142.7 0.0 1.7e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 EMC79579.1 - 9e-36 122.7 88.1 8.6e-29 100.1 29.4 4.3 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.18 EMC79579.1 - 0.0047 16.6 0.1 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC79579.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Adeno_E3_CR2 PF02439.10 EMC79579.1 - 0.21 11.1 2.1 0.56 9.8 1.5 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CPSase_L_D2 PF02786.12 EMC79580.1 - 1e-113 377.8 0.7 5.6e-82 274.1 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EMC79580.1 - 2.4e-39 133.8 0.0 5.1e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EMC79580.1 - 1.6e-36 124.7 0.0 3.2e-19 69.0 0.0 3.0 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 EMC79580.1 - 5.4e-36 123.8 0.0 9.7e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ATP-grasp_4 PF13535.1 EMC79580.1 - 3.9e-30 104.9 0.6 7.7e-17 61.6 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain CPSase_sm_chain PF00988.17 EMC79580.1 - 5.5e-26 90.6 0.0 1.3e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain MGS PF02142.17 EMC79580.1 - 1e-21 76.6 0.0 1.6e-20 72.8 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.17 EMC79580.1 - 1.1e-17 63.9 0.3 1.6e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC79580.1 - 8e-16 57.6 0.0 3.7e-07 29.2 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMC79580.1 - 1.9e-12 47.0 0.7 3.3e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EMC79580.1 - 1.3e-05 25.0 0.1 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EMC79580.1 - 0.00044 19.7 0.1 0.47 9.8 0.0 2.7 2 1 0 2 2 2 2 RimK-like ATP-grasp domain DUF977 PF06163.6 EMC79580.1 - 0.11 12.1 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) LANC_like PF05147.8 EMC79581.1 - 2.1e-82 276.5 0.5 2.6e-82 276.2 0.3 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 EMC79581.1 - 0.047 12.9 0.2 0.9 8.7 0.0 2.6 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 EMC79581.1 - 0.081 11.9 0.0 11 4.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EMC79581.1 - 0.09 11.0 0.0 4.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) EF-hand_7 PF13499.1 EMC79582.1 - 1.7e-12 47.2 0.1 3.8e-07 30.1 0.0 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC79582.1 - 9.2e-12 43.7 1.1 0.00042 19.9 0.2 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EMC79582.1 - 4.4e-11 41.2 5.7 0.019 14.2 0.0 5.2 5 1 1 6 6 6 3 EF hand EF-hand_8 PF13833.1 EMC79582.1 - 2.8e-06 26.8 1.5 0.091 12.3 0.1 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 EMC79582.1 - 0.0013 18.5 0.0 1.7 8.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EMC79582.1 - 0.019 14.5 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF2267 PF10025.4 EMC79582.1 - 0.088 12.8 0.1 0.68 10.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Acyl-CoA_dh_1 PF00441.19 EMC79583.1 - 6.7e-42 143.1 0.1 1e-41 142.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC79583.1 - 3.2e-29 101.7 0.0 8e-29 100.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMC79583.1 - 8.9e-19 66.7 0.7 5.7e-18 64.1 0.1 2.4 1 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC79583.1 - 1.5e-08 34.9 0.0 2.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EMC79583.1 - 0.016 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal TctA PF01970.11 EMC79583.1 - 0.19 10.0 0.0 0.28 9.5 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family PEHE PF15275.1 EMC79584.1 - 1.1e-23 84.0 5.5 1.1e-23 84.0 3.8 3.7 4 0 0 4 4 4 1 PEHE domain Ribul_P_3_epim PF00834.14 EMC79585.1 - 3.4e-45 153.6 0.1 4e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EMC79585.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 EMC79585.1 - 0.0032 16.8 0.0 0.0063 15.9 0.0 1.3 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.12 EMC79585.1 - 0.006 15.7 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 EMC79585.1 - 0.097 11.9 0.0 0.32 10.2 0.0 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein PG_binding_3 PF09374.5 EMC79585.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Tubulin-binding PF00418.14 EMC79587.1 - 3.4e-65 215.3 23.5 5.3e-17 61.2 1.8 5.4 5 0 0 5 5 5 4 Tau and MAP protein, tubulin-binding repeat RII_binding_1 PF10522.4 EMC79587.1 - 0.0057 16.6 1.2 0.017 15.1 0.9 1.9 1 0 0 1 1 1 1 RII binding domain DUF1880 PF08976.6 EMC79587.1 - 0.86 9.7 10.2 0.042 13.9 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Nckap1 PF09735.4 EMC79588.1 - 0 1773.8 26.9 0 1773.6 18.6 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Nup35_RRM PF05172.8 EMC79589.1 - 4.7e-27 93.6 0.1 7.9e-27 92.9 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EMC79589.1 - 1.8e-14 53.2 0.0 2.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EMC79589.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EMC79590.1 - 1.5e-05 24.9 8.8 1.5e-05 24.9 6.1 3.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding BIR PF00653.16 EMC79591.1 - 3.6e-20 72.1 4.4 4.3e-20 71.9 3.0 1.1 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 EMC79591.1 - 0.00079 19.2 0.8 0.0008 19.1 0.5 1.2 1 0 0 1 1 1 1 C3HC zinc finger-like Dynein_heavy PF03028.10 EMC79592.1 - 4e-249 828.4 0.0 8.5e-249 827.3 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EMC79592.1 - 1.8e-134 448.3 3.3 1.8e-134 448.3 2.3 4.1 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EMC79592.1 - 2e-92 308.8 1.1 4.2e-92 307.8 0.1 2.2 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EMC79592.1 - 2.7e-74 249.5 1.0 7.5e-73 244.7 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EMC79592.1 - 5.3e-62 208.6 0.1 2.9e-61 206.2 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 EMC79592.1 - 3.3e-58 197.1 5.0 3.3e-58 197.1 3.5 2.4 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 EMC79592.1 - 3.1e-51 174.0 0.0 6.6e-51 172.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 EMC79592.1 - 4.2e-21 75.1 0.0 0.0002 21.1 0.0 5.8 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMC79592.1 - 3.8e-06 27.0 4.8 0.11 12.6 0.0 5.5 6 0 0 6 6 6 1 AAA domain AAA PF00004.24 EMC79592.1 - 4e-06 27.0 3.2 1.4 9.1 0.0 5.7 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC79592.1 - 0.00036 20.5 0.0 3.5 7.5 0.0 4.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EMC79592.1 - 0.00055 19.6 0.0 1.9 8.3 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 EMC79592.1 - 0.0008 20.2 0.0 1 10.1 0.0 4.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMC79592.1 - 0.0017 18.4 0.1 6.9 6.9 0.0 3.8 4 0 0 4 4 2 0 RNA helicase AAA_18 PF13238.1 EMC79592.1 - 0.0021 18.3 0.0 0.71 10.1 0.0 4.3 3 0 0 3 3 2 1 AAA domain EF-hand_1 PF00036.27 EMC79592.1 - 0.0049 16.0 1.4 0.024 13.9 0.9 2.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EMC79592.1 - 0.027 13.7 1.0 0.083 12.2 0.7 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EMC79592.1 - 0.028 14.2 1.9 0.13 12.2 1.3 2.2 1 0 0 1 1 1 0 EF-hand domain AAA_33 PF13671.1 EMC79592.1 - 0.036 13.9 0.0 1.6 8.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EMC79592.1 - 0.063 12.6 0.1 4.8 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain HrpB7 PF09486.5 EMC79592.1 - 0.29 11.0 15.6 3.5 7.5 5.3 3.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FUSC PF04632.7 EMC79592.1 - 6.8 4.9 1.7 13 4.0 1.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Zip PF02535.17 EMC79594.1 - 9.8e-97 323.7 25.9 9.8e-97 323.7 17.9 5.6 2 2 0 3 3 3 1 ZIP Zinc transporter Kazal_2 PF07648.10 EMC79595.1 - 3.2e-17 62.1 17.4 1.6e-10 40.7 3.9 4.1 5 0 0 5 5 5 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC79595.1 - 3e-14 52.7 25.8 1e-09 38.2 4.5 4.6 3 3 1 4 4 4 2 Kazal-type serine protease inhibitor domain hEGF PF12661.2 EMC79595.1 - 0.0011 18.9 3.4 0.0011 18.9 2.3 4.4 4 0 0 4 4 4 1 Human growth factor-like EGF Serglycin PF04360.7 EMC79595.1 - 0.053 13.2 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Serglycin EphA2_TM PF14575.1 EMC79595.1 - 0.068 13.5 1.7 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PTRF_SDPR PF15237.1 EMC79596.1 - 8.1e-87 290.6 13.9 8.1e-87 290.6 9.7 2.5 2 1 0 2 2 2 1 PTRF/SDPR family YlbD_coat PF14071.1 EMC79596.1 - 0.0076 16.3 2.1 0.0076 16.3 1.4 2.3 3 0 0 3 3 3 1 Putative coat protein GRA6 PF05084.8 EMC79596.1 - 3.4 7.1 11.9 0.074 12.5 2.7 2.1 2 0 0 2 2 2 0 Granule antigen protein (GRA6) tRNA_anti-codon PF01336.20 EMC79597.1 - 0.0026 17.5 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain KRTAP PF11759.3 EMC79597.1 - 3.1 8.1 8.6 0.37 11.0 2.8 1.7 2 0 0 2 2 2 0 Keratin-associated matrix Pkinase PF00069.20 EMC79598.1 - 5.1e-24 84.8 0.1 5.5e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79598.1 - 2.3e-17 62.9 0.1 2.5e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC79598.1 - 2.9e-05 23.2 0.0 3.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC79598.1 - 0.0007 18.6 0.0 0.00086 18.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC79598.1 - 0.091 12.1 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EMC79598.1 - 0.13 11.9 0.2 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EMC79599.1 - 2e-58 197.5 0.0 2.3e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79599.1 - 1.2e-33 116.3 0.0 1.4e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79599.1 - 1.6e-07 30.5 0.0 3.5e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC79599.1 - 0.00012 21.1 0.0 0.00062 18.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC79599.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Myosin_head PF00063.16 EMC79600.1 - 1.6e-254 846.1 1.6 2.5e-254 845.5 1.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EMC79600.1 - 2e-47 161.1 1.7 2e-47 161.1 1.1 2.1 2 0 0 2 2 2 1 Myosin tail IQ PF00612.22 EMC79600.1 - 0.0051 16.3 27.0 0.12 12.0 0.1 6.3 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_17 PF13207.1 EMC79600.1 - 0.012 16.4 0.4 0.16 12.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EMC79600.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EMC79600.1 - 0.033 13.4 1.0 1.1 8.5 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF2215 PF10225.4 EMC79601.1 - 3.5e-75 252.6 6.0 4.8e-75 252.2 4.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) Kringle PF00051.13 EMC79601.1 - 0.42 10.7 3.6 4.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Kringle domain MFS_1 PF07690.11 EMC79602.1 - 2.2e-32 112.1 22.0 4.4e-17 61.8 8.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC79602.1 - 5.5e-17 61.3 3.7 5.5e-17 61.3 2.6 2.9 4 0 0 4 4 4 1 MFS_1 like family MFS_2 PF13347.1 EMC79602.1 - 7.7e-12 44.3 10.7 2.6e-10 39.2 4.4 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 EMC79602.1 - 8.4e-08 31.3 7.0 8.4e-08 31.3 4.8 3.6 3 1 0 3 3 3 1 Nucleoside H+ symporter LacY_symp PF01306.14 EMC79602.1 - 9e-07 27.7 18.3 0.0011 17.5 2.6 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter ATG22 PF11700.3 EMC79602.1 - 5.1e-05 21.9 18.1 0.065 11.7 0.1 3.2 3 0 0 3 3 3 3 Vacuole effluxer Atg22 like MFS_3 PF05977.8 EMC79602.1 - 0.00014 20.1 2.0 0.00049 18.3 0.4 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3671 PF12420.3 EMC79602.1 - 0.32 10.9 2.5 0.54 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function OppC_N PF12911.2 EMC79602.1 - 0.34 10.3 11.4 1.1 8.7 0.0 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ECH_C PF13766.1 EMC79603.1 - 4.3e-45 152.6 0.1 1e-44 151.4 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EMC79603.1 - 5e-36 124.0 0.0 5.4e-34 117.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Thioredox_DsbH PF03190.10 EMC79603.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 TGFb_propeptide PF00688.13 EMC79604.1 - 2.1e-48 164.7 0.0 2.7e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC79604.1 - 7.5e-18 64.7 1.4 7e-12 45.5 0.6 2.8 1 1 1 2 2 2 2 Transforming growth factor beta like domain ORMDL PF04061.9 EMC79605.1 - 7.9e-53 177.6 3.3 8.9e-53 177.4 2.3 1.0 1 0 0 1 1 1 1 ORMDL family DUF846 PF05832.7 EMC79605.1 - 4 7.1 7.6 3.9 7.1 1.3 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) Peptidase_M22 PF00814.20 EMC79606.1 - 7e-57 192.9 1.5 8.1e-57 192.7 1.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Peptidase_S32 PF05579.8 EMC79606.1 - 0.015 14.2 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Asn_synthase PF00733.16 EMC79607.1 - 3.4e-66 223.3 0.0 5.3e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMC79607.1 - 6.7e-07 29.0 0.0 6e-06 26.0 0.0 2.5 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMC79607.1 - 0.00073 19.5 0.0 0.0033 17.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.15 EMC79607.1 - 0.0092 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EMC79607.1 - 0.085 11.7 0.3 0.4 9.5 0.1 1.9 1 1 1 2 2 2 0 NAD synthase QueC PF06508.8 EMC79607.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC FPN1 PF06963.7 EMC79608.1 - 1.5e-182 606.8 12.8 1.7e-182 606.6 8.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.11 EMC79608.1 - 2.5e-06 26.4 31.6 1.3e-05 24.0 1.7 3.7 3 1 1 4 4 4 3 Major Facilitator Superfamily DUF347 PF03988.7 EMC79608.1 - 0.035 13.9 10.1 0.12 12.3 0.1 4.1 3 1 0 3 3 3 0 Repeat of Unknown Function (DUF347) WD40 PF00400.27 EMC79609.1 - 0.0065 16.3 10.2 0.36 10.8 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat TGFb_propeptide PF00688.13 EMC79610.1 - 5.2e-42 143.7 0.0 6.3e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC79610.1 - 4.7e-34 116.8 0.1 7.8e-34 116.1 0.1 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain Ion_trans PF00520.26 EMC79611.1 - 4.9e-25 87.9 7.7 4.9e-25 87.9 5.4 1.7 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC79611.1 - 6.1e-25 87.2 0.0 1.3e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC79611.1 - 2.3e-11 43.2 4.6 2.3e-11 43.2 3.2 2.2 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC79611.1 - 0.0025 16.3 6.1 0.0099 14.3 4.2 1.9 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.2 EMC79612.1 - 4.4e-36 123.0 13.0 8.4e-15 54.8 0.9 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC79612.1 - 8.4e-25 86.6 4.5 2.5e-11 43.7 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EMC79612.1 - 2.1e-23 80.8 10.4 3.9e-05 23.2 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EMC79612.1 - 1.9e-21 75.6 9.7 5.2e-12 45.5 0.2 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC79612.1 - 2.4e-17 61.2 6.5 0.00013 21.8 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat zf-CHY PF05495.7 EMC79612.1 - 0.061 13.4 0.5 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 CHY zinc finger SDA1 PF05285.7 EMC79612.1 - 0.4 9.9 8.9 0.51 9.5 6.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EMC79612.1 - 0.46 8.4 6.3 0.59 8.1 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMC79612.1 - 0.74 7.6 11.1 0.98 7.2 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family Fibrinogen_C PF00147.13 EMC79613.1 - 1.8e-62 211.0 0.8 3.7e-62 210.0 0.6 1.5 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DivIC PF04977.10 EMC79613.1 - 0.39 10.2 6.4 0.72 9.3 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Ras PF00071.17 EMC79614.1 - 4.6e-24 84.6 0.1 4.9e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC79614.1 - 2.2e-08 34.6 0.0 2.2e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC79614.1 - 0.00035 19.8 0.0 0.00039 19.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC79614.1 - 0.00076 19.4 0.0 0.00084 19.2 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC79614.1 - 0.063 12.4 0.1 0.064 12.4 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 EMC79614.1 - 0.091 11.7 0.0 0.099 11.6 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain RINGv PF12906.2 EMC79617.1 - 6.9e-15 54.8 7.4 6.9e-15 54.8 5.2 3.1 4 0 0 4 4 4 1 RING-variant domain Vpu PF00558.14 EMC79617.1 - 0.0087 15.5 0.2 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Vpu protein zf-Apc11 PF12861.2 EMC79617.1 - 0.038 13.8 0.9 0.038 13.8 0.6 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMC79617.1 - 0.041 13.8 3.7 0.15 12.1 2.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMC79617.1 - 0.38 10.7 6.4 0.4 10.6 1.6 2.7 2 1 1 3 3 3 0 FANCL C-terminal domain zf-rbx1 PF12678.2 EMC79617.1 - 2.2 8.4 6.9 8 6.6 3.2 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EMC79617.1 - 4.1 7.3 10.5 0.94 9.3 4.4 2.2 2 0 0 2 2 2 0 Ring finger domain PRY PF13765.1 EMC79619.1 - 4e-22 77.4 0.0 6e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 EMC79619.1 - 6.5e-15 55.3 0.0 6.2e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 SPRY domain PRY PF13765.1 EMC79620.1 - 5.1e-19 67.5 0.0 1.3e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.23 EMC79620.1 - 1.4e-14 54.2 0.0 1.8e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Myelin_PLP PF01275.14 EMC79621.1 - 2.1e-74 249.9 14.8 2.4e-74 249.7 10.2 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF2701 PF10857.3 EMC79621.1 - 0.19 11.4 3.8 0.2 11.4 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2701) DUF2244 PF10003.4 EMC79621.1 - 0.64 9.3 0.0 0.64 9.3 0.0 2.8 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) DUF1003 PF06210.6 EMC79621.1 - 5.6 6.9 7.4 47 3.9 5.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) EF-hand_1 PF00036.27 EMC79622.1 - 1.2e-05 24.2 0.7 1.2e-05 24.2 0.5 2.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EMC79622.1 - 0.00013 22.0 1.4 0.00021 21.3 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC79622.1 - 0.00092 18.7 0.5 0.0023 17.4 0.2 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC79622.1 - 0.016 14.5 0.4 0.042 13.1 0.3 1.8 1 0 0 1 1 1 0 EF hand Mit_ribos_Mrp51 PF11709.3 EMC79622.1 - 0.12 11.6 0.5 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Decorin_bind PF02352.10 EMC79622.1 - 0.88 9.5 5.3 5.5 6.9 1.7 2.3 2 1 0 2 2 2 0 Decorin binding protein IRK PF01007.15 EMC79623.1 - 6.6e-89 298.0 0.0 7.5e-89 297.8 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC79623.1 - 0.00013 21.5 2.8 0.00029 20.4 2.0 1.6 1 1 0 1 1 1 1 Ion channel GYF PF02213.11 EMC79624.1 - 5.7e-20 70.6 2.0 1.5e-19 69.3 1.4 1.8 1 0 0 1 1 1 1 GYF domain RhoGEF PF00621.15 EMC79626.1 - 9.2e-38 129.9 8.2 1.7e-37 129.0 5.7 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 EMC79626.1 - 1.9e-12 46.3 0.0 5.7e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC79626.1 - 2e-11 43.2 0.0 4.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC79626.1 - 1.2e-07 31.0 0.0 2.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC79626.1 - 0.0006 19.9 0.4 0.0021 18.2 0.0 2.1 2 1 0 2 2 2 1 PH domain BNR_2 PF13088.1 EMC79627.1 - 1.2e-29 103.4 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EMC79627.1 - 0.046 13.5 5.6 0.14 12.0 0.1 3.7 4 0 0 4 4 4 0 BNR/Asp-box repeat Exo_endo_phos PF03372.18 EMC79628.1 - 2.7e-25 89.7 0.0 1.3e-24 87.5 0.0 2.1 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family SH2 PF00017.19 EMC79628.1 - 9.5e-18 63.7 0.0 3.5e-17 61.9 0.0 2.1 1 0 0 1 1 1 1 SH2 domain Imm11 PF15563.1 EMC79628.1 - 0.0022 17.1 0.1 0.0061 15.6 0.1 1.7 1 0 0 1 1 1 1 Immunity protein 11 ATG16 PF08614.6 EMC79629.1 - 3.1e-53 180.5 25.3 3.1e-53 180.5 17.5 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.27 EMC79629.1 - 2.2e-42 141.4 14.5 1.7e-09 37.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC79629.1 - 1.2e-06 28.3 0.0 0.19 11.4 0.0 3.4 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC79629.1 - 0.00013 20.3 6.8 0.94 7.5 0.0 4.6 2 1 2 5 5 5 3 Nucleoporin Nup120/160 DUF4200 PF13863.1 EMC79629.1 - 0.011 15.6 22.9 0.011 15.6 15.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 EMC79629.1 - 0.024 14.9 8.9 0.024 14.9 6.2 3.5 1 1 2 3 3 2 0 Protein of unknown function (DUF904) ERM PF00769.14 EMC79629.1 - 0.066 12.7 33.0 0.024 14.2 20.9 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HTH_6 PF01418.12 EMC79629.1 - 0.071 12.8 0.9 0.19 11.4 0.6 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family V_ATPase_I PF01496.14 EMC79629.1 - 0.091 10.6 14.0 0.12 10.1 9.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EMC79629.1 - 0.19 10.8 1.7 0.35 9.9 1.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Hira PF07569.6 EMC79629.1 - 0.67 9.1 0.0 0.67 9.1 0.0 3.3 4 1 1 5 5 5 0 TUP1-like enhancer of split DUF641 PF04859.7 EMC79629.1 - 0.95 9.2 14.0 0.1 12.3 3.7 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 EMC79629.1 - 1 9.7 22.0 0.2 12.0 5.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TBPIP PF07106.8 EMC79629.1 - 1 8.8 24.5 0.054 13.0 11.3 2.3 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EMC79629.1 - 1.3 9.3 5.1 0.61 10.3 0.5 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Synaptobrevin PF00957.16 EMC79629.1 - 1.4 8.5 6.5 2.1 7.9 3.4 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF1664 PF07889.7 EMC79629.1 - 1.5 8.6 7.2 4.4 7.1 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EMC79629.1 - 2.2 7.8 36.1 0.14 11.7 13.8 2.3 1 1 1 2 2 2 0 IncA protein Allexi_40kDa PF05549.6 EMC79629.1 - 2.3 7.4 8.4 3.3 6.9 5.0 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein BLOC1_2 PF10046.4 EMC79629.1 - 2.5 8.2 16.6 0.2 11.8 3.0 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EMC79629.1 - 8 6.4 8.0 0.26 11.2 0.7 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 EMC79629.1 - 9.2 6.7 18.0 0.24 11.8 3.1 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Arrestin_N PF00339.24 EMC79630.1 - 7.2e-38 129.7 0.4 2.2e-33 115.1 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMC79630.1 - 6.8e-25 87.7 1.7 1e-24 87.1 1.2 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Gryzun PF07919.7 EMC79630.1 - 0.011 14.1 0.3 0.014 13.7 0.2 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi Transglut_C PF00927.17 EMC79630.1 - 0.012 15.6 1.5 0.07 13.1 1.2 2.1 1 1 1 2 2 2 0 Transglutaminase family, C-terminal ig like domain DUF974 PF06159.8 EMC79630.1 - 0.021 14.3 0.2 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF974) DUF2079 PF09852.4 EMC79630.1 - 0.04 12.6 0.1 0.054 12.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF2393 PF09624.5 EMC79630.1 - 0.075 12.5 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DAGK_acc PF00609.14 EMC79631.1 - 1.1e-52 178.4 0.0 2.2e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EMC79631.1 - 1.1e-29 102.4 0.0 2.4e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EMC79631.1 - 3.8e-20 71.3 25.0 1.5e-11 43.8 3.8 2.8 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.12 EMC79631.1 - 2.9e-19 68.6 0.9 1.2e-18 66.6 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC79631.1 - 1.6e-17 63.4 2.3 1.2e-16 60.6 0.3 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.24 EMC79631.1 - 2.6e-16 59.7 0.3 6.8e-16 58.3 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC79631.1 - 6.4e-08 32.8 4.3 7.2e-07 29.4 1.3 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EMC79631.1 - 8.3e-05 22.5 0.2 0.00019 21.4 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C1_3 PF07649.7 EMC79631.1 - 0.0063 16.5 2.8 0.0063 16.5 2.0 3.0 2 1 0 2 2 2 1 C1-like domain Mcp5_PH PF12814.2 EMC79631.1 - 0.008 16.1 0.1 0.023 14.5 0.1 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology LIM PF00412.17 EMC79632.1 - 3e-61 203.3 59.8 2.5e-14 53.0 2.3 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.16 EMC79633.1 - 6.1e-54 182.8 18.6 8.5e-54 182.3 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC79633.1 - 4e-07 29.4 19.1 4.8e-07 29.2 13.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC79633.1 - 0.00036 19.7 16.8 0.00036 19.7 11.7 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.1 EMC79633.1 - 0.016 14.9 11.7 0.015 15.0 6.4 2.3 1 1 0 1 1 1 0 Olfactory receptor Srg PF02118.16 EMC79633.1 - 0.023 14.1 19.7 0.036 13.5 13.6 1.5 1 1 0 1 1 1 0 Srg family chemoreceptor Glycolytic PF00274.14 EMC79634.1 - 1.6e-07 30.0 0.1 1.8e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I p450 PF00067.17 EMC79635.1 - 9.7e-109 363.9 0.0 1.1e-108 363.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1819 PF08849.6 EMC79635.1 - 0.037 13.4 0.6 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) Syndecan PF01034.15 EMC79639.1 - 1.6e-31 107.7 0.1 3.7e-31 106.5 0.0 1.6 2 0 0 2 2 2 1 Syndecan domain Yip1 PF04893.12 EMC79639.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain Glycophorin_A PF01102.13 EMC79639.1 - 0.88 9.3 8.2 0.14 11.9 1.6 2.6 1 1 1 2 2 2 0 Glycophorin A PUF PF00806.14 EMC79640.1 - 2.9e-74 240.5 8.7 8.9e-10 37.5 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Mt_ATP-synt_B PF05405.9 EMC79640.1 - 3.4 7.1 5.9 9.8 5.6 0.1 3.0 3 1 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease_2 PF13520.1 EMC79641.1 - 4e-56 190.3 46.5 5.1e-56 190.0 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC79641.1 - 2.8e-25 88.6 42.6 4.3e-25 87.9 29.5 1.2 1 1 0 1 1 1 1 Amino acid permease Ras PF00071.17 EMC79642.1 - 1.1e-57 193.9 0.0 1.3e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC79642.1 - 2.4e-17 63.5 0.0 3.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC79642.1 - 8.4e-11 41.4 0.0 1.5e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC79642.1 - 6.9e-05 22.3 0.1 0.00016 21.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC79642.1 - 0.0056 15.8 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMC79642.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Hormone_3 PF00159.13 EMC79643.1 - 1.4e-19 69.7 2.3 2.4e-19 69.0 1.6 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide HEAT PF02985.17 EMC79644.1 - 2.6e-15 55.0 2.6 0.0076 16.2 0.0 7.2 6 1 1 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EMC79644.1 - 5e-09 36.3 0.1 0.00088 19.5 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EMC79644.1 - 0.00027 21.3 6.4 0.81 10.2 0.0 5.2 5 1 1 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.15 EMC79644.1 - 0.00053 18.4 0.3 0.0071 14.7 0.0 2.2 2 0 0 2 2 2 1 Adaptin N terminal region DUF4140 PF13600.1 EMC79644.1 - 0.03 14.7 0.6 5.1 7.6 0.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nuc_H_symport PF03825.11 EMC79644.1 - 0.087 11.5 0.1 4.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Nucleoside H+ symporter PigN PF04987.9 EMC79645.1 - 3.7e-133 444.4 46.8 4.9e-133 444.0 32.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EMC79645.1 - 2e-14 53.7 0.0 2.9e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMC79645.1 - 1.7e-05 24.3 0.0 3.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EMC79645.1 - 8.3e-05 21.9 0.0 0.00018 20.7 0.0 1.6 2 0 0 2 2 2 1 Sulfatase zf-RING_5 PF14634.1 EMC79646.1 - 9.7e-08 31.6 11.3 9.7e-08 31.6 7.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC79646.1 - 3.7e-07 29.6 12.7 7.1e-07 28.7 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC79646.1 - 7e-06 25.6 10.3 1.7e-05 24.3 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC79646.1 - 7.8e-06 25.6 13.1 7.8e-06 25.6 9.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC79646.1 - 0.00021 21.2 13.2 0.00021 21.2 9.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC79646.1 - 0.00058 19.6 11.8 0.00058 19.6 8.2 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC79646.1 - 0.0013 18.3 9.3 0.0027 17.4 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EMC79646.1 - 2 8.0 13.8 7.4 6.2 9.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Cadherin PF00028.12 EMC79647.1 - 1.3e-81 268.9 2.1 2.1e-18 66.3 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC79647.1 - 8.6e-52 175.1 1.1 1.2e-51 174.6 0.1 1.7 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC79647.1 - 3.8e-05 23.1 0.0 0.76 9.3 0.0 4.2 4 0 0 4 4 4 2 Cadherin-like O-antigen_lig PF13425.1 EMC79647.1 - 0.044 13.7 0.9 0.1 12.5 0.6 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Cadherin PF00028.12 EMC79648.1 - 3.9e-80 264.2 5.3 7.6e-20 70.9 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC79648.1 - 4.9e-56 188.9 0.6 1.3e-55 187.5 0.4 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC79648.1 - 0.0003 20.2 0.0 1.5 8.3 0.0 4.1 4 1 0 4 4 4 2 Cadherin-like ASFV_J13L PF05568.6 EMC79648.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Yae1_N PF09811.4 EMC79649.1 - 1.4e-12 46.9 42.6 0.00019 20.8 5.4 5.1 2 1 3 5 5 5 5 Essential protein Yae1, N terminal RVT_1 PF00078.22 EMC79651.1 - 0.037 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_2c PF01411.14 EMC79652.1 - 3.9e-204 679.0 0.0 2.1e-171 570.9 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EMC79652.1 - 2.1e-16 59.5 0.0 5e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EMC79652.1 - 1.5e-08 34.2 0.2 1.3e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 DHHA1 domain Med11 PF10280.4 EMC79652.1 - 0.0076 16.2 0.0 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 Mediator complex protein EntA_Immun PF08951.5 EMC79652.1 - 0.031 14.4 2.3 0.21 11.7 0.3 2.5 2 0 0 2 2 2 0 Enterocin A Immunity GTP_EFTU_D4 PF14578.1 EMC79652.1 - 0.031 13.8 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Asp-B-Hydro_N PF05279.6 EMC79652.1 - 0.069 12.9 3.2 0.14 12.0 2.2 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lipase_GDSL_3 PF14606.1 EMC79652.1 - 0.12 12.1 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.20 EMC79653.1 - 2.8e-18 66.3 0.6 5.7e-18 65.3 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC79653.1 - 6.2e-10 39.0 0.1 1.8e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMC79653.1 - 0.053 13.5 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 EMC79654.1 - 2.7e-21 76.2 0.1 4.1e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC79654.1 - 1.1e-10 41.4 0.0 1.7e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC79654.1 - 2.8e-05 24.0 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EMC79654.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family KorB PF08535.5 EMC79654.1 - 0.14 12.3 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 KorB domain zf-H2C2_2 PF13465.1 EMC79656.1 - 1.1e-54 180.1 93.1 4.3e-08 33.0 2.1 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79656.1 - 1.9e-31 106.4 104.6 0.00026 21.1 0.7 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79656.1 - 2.7e-24 83.6 91.4 0.00092 19.3 2.2 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79656.1 - 1.2e-08 34.8 64.5 0.012 15.7 0.3 11.2 9 1 2 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC79656.1 - 2.1e-05 24.4 16.0 0.00019 21.4 0.6 10.7 11 1 0 11 11 11 4 C2H2-type zinc-finger domain zf-met PF12874.2 EMC79656.1 - 0.011 15.9 1.5 0.011 15.9 1.1 10.2 11 0 0 11 11 11 0 Zinc-finger of C2H2 type GAGA PF09237.6 EMC79656.1 - 1.3 8.7 30.9 2.9 7.5 0.0 8.0 1 1 9 10 10 10 0 GAGA factor zf-C2H2_2 PF12756.2 EMC79656.1 - 2.2 8.4 61.1 2.3 8.4 4.8 7.5 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EMC79656.1 - 4.2 7.4 68.0 0.056 13.3 1.4 10.3 11 1 0 11 11 11 0 C2H2-type zinc finger TFIIF_alpha PF05793.7 EMC79656.1 - 4.6 5.5 24.7 0.057 11.7 9.1 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HEAT_2 PF13646.1 EMC79657.1 - 2.3e-10 40.6 8.5 7.4e-06 26.1 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats HR1 PF02185.11 EMC79658.1 - 0.00022 20.8 0.6 0.0017 18.0 0.0 2.3 2 0 0 2 2 2 1 Hr1 repeat Uds1 PF15456.1 EMC79658.1 - 0.00038 20.4 0.2 0.00038 20.4 0.2 1.8 2 0 0 2 2 2 1 Up-regulated During Septation Nbl1_Borealin_N PF10444.4 EMC79658.1 - 0.031 13.6 0.1 0.11 11.8 0.0 2.0 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal adh_short PF00106.20 EMC79659.1 - 1.1e-16 61.2 0.0 1.7e-16 60.5 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC79659.1 - 8.4e-07 28.8 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC79659.1 - 0.037 14.0 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 EMC79660.1 - 4e-22 78.8 0.1 5.9e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC79660.1 - 1.4e-11 44.3 0.1 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC79660.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EMC79660.1 - 0.014 14.7 0.0 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 EMC79660.1 - 0.039 13.9 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding LCAT PF02450.10 EMC79661.1 - 9.4e-124 413.3 0.8 1.1e-123 413.0 0.6 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EMC79661.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EMC79661.1 - 5.6e-05 22.3 0.0 0.00061 18.9 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.5 EMC79661.1 - 0.0006 18.7 0.0 0.00098 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PGAP1 PF07819.8 EMC79661.1 - 0.0011 18.5 0.0 0.0046 16.5 0.0 2.0 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EMC79661.1 - 0.002 17.8 0.0 0.0048 16.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family HAD_2 PF13419.1 EMC79661.1 - 0.025 14.8 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF676 PF05057.9 EMC79661.1 - 0.027 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.7 EMC79661.1 - 0.04 13.2 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 EMC79661.1 - 0.069 12.7 0.0 0.42 10.1 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1704 PF08014.6 EMC79662.1 - 8.3e-13 48.0 0.0 1.4e-12 47.3 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) DUF788 PF05620.6 EMC79663.1 - 3.1e-39 134.5 0.0 3.9e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF3361 PF11841.3 EMC79664.1 - 9.8e-56 187.9 4.8 2.3e-55 186.6 3.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 EMC79664.1 - 4.6e-49 166.2 0.2 9.9e-49 165.1 0.2 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family DUF1910 PF08928.5 EMC79664.1 - 0.0046 16.9 1.2 2.9 7.9 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1910) E2F_TDP PF02319.15 EMC79665.1 - 1.1e-14 53.7 0.1 2.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DivIC PF04977.10 EMC79665.1 - 0.11 12.0 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Sec6 PF06046.8 EMC79666.1 - 2.1e-124 415.6 1.3 3.1e-124 415.1 0.9 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Sec8_exocyst PF04048.9 EMC79666.1 - 0.031 13.8 0.4 0.031 13.8 0.3 2.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Ribosomal_S20p PF01649.13 EMC79666.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S20 RE_TdeIII PF09520.5 EMC79666.1 - 0.12 11.6 0.1 0.31 10.3 0.1 1.6 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Pkinase PF00069.20 EMC79668.1 - 1.7e-73 247.0 0.0 2.3e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79668.1 - 1.6e-35 122.4 0.0 2.2e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79668.1 - 3.6e-07 29.4 0.0 3.6e-05 22.8 0.0 2.4 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 EMC79668.1 - 6.9e-05 22.6 0.0 0.19 11.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC79668.1 - 0.006 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EMC79669.1 - 0.00023 20.9 0.1 0.0047 16.7 0.1 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat NTF2 PF02136.15 EMC79670.1 - 5e-34 117.2 0.0 5.5e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 EMC79670.1 - 0.066 13.4 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Fcf1 PF04900.7 EMC79670.1 - 0.066 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Fcf1 SnoaL_4 PF13577.1 EMC79670.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain CENP-T PF15511.1 EMC79671.1 - 4.3e-21 75.6 0.1 5.2e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EMC79671.1 - 1.8e-08 34.4 0.0 2.7e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC79671.1 - 7.5e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC79671.1 - 0.00079 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EMC79671.1 - 0.022 14.5 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EMC79671.1 - 0.04 14.0 0.1 0.054 13.6 0.1 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 IL8 PF00048.15 EMC79672.1 - 7.2e-16 57.9 0.4 8.7e-16 57.6 0.3 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 EMC79673.1 - 8.1e-17 60.9 0.0 9.3e-17 60.7 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF3627 PF12299.3 EMC79674.1 - 0.081 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) IL8 PF00048.15 EMC79675.1 - 0.012 15.5 0.8 0.015 15.2 0.6 1.2 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like MARVEL PF01284.18 EMC79676.1 - 7.7e-16 58.2 23.3 9.1e-16 57.9 16.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Claudin_3 PF06653.6 EMC79676.1 - 8.1 6.1 16.0 18 5.0 11.1 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like ARL2_Bind_BART PF11527.3 EMC79677.1 - 1.9e-31 108.3 5.4 2.3e-31 108.1 3.7 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART HIF-1 PF11413.3 EMC79677.1 - 0.094 11.9 1.6 0.25 10.5 1.1 1.7 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 DUF1269 PF06897.7 EMC79677.1 - 0.1 12.6 0.1 10 6.2 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1269) Phi-29_GP3 PF05435.6 EMC79677.1 - 0.17 11.0 2.8 0.22 10.6 2.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Nefa_Nip30_N PF10187.4 EMC79678.1 - 3.8e-35 120.1 22.2 7.9e-35 119.1 15.4 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Herpes_capsid PF06112.6 EMC79678.1 - 0.85 9.6 5.3 1.6 8.7 3.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SieB PF14163.1 EMC79678.1 - 3.1 7.3 8.1 0.4 10.2 1.6 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B Copine PF07002.11 EMC79679.1 - 8.6e-60 200.7 0.1 1.9e-59 199.6 0.0 1.6 2 0 0 2 2 2 1 Copine C2 PF00168.25 EMC79679.1 - 1.1e-28 98.9 0.1 8.7e-14 51.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EMC79679.1 - 5.1e-10 39.5 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus NACHT PF05729.7 EMC79680.1 - 1.7e-35 122.1 0.1 5e-35 120.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 EMC79680.1 - 3e-32 107.0 49.0 0.00094 19.0 0.5 17.0 17 1 1 18 18 17 8 Leucine Rich repeat LRR_4 PF12799.2 EMC79680.1 - 9.4e-14 50.6 49.0 0.0019 17.7 0.9 13.4 11 4 6 17 17 17 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79680.1 - 2.7e-13 49.4 42.9 0.095 12.4 0.2 11.5 8 2 1 11 11 11 6 Leucine rich repeat AAA PF00004.24 EMC79680.1 - 2.9e-06 27.5 0.0 7.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMC79680.1 - 0.00048 19.5 0.0 0.094 12.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain LRR_1 PF00560.28 EMC79680.1 - 0.0027 17.5 48.0 13 6.3 0.0 14.7 14 1 1 15 15 15 0 Leucine Rich Repeat AAA_22 PF13401.1 EMC79680.1 - 0.014 15.4 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMC79680.1 - 0.02 14.0 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMC79680.1 - 0.034 14.0 0.2 0.13 12.1 0.1 2.1 2 0 0 2 2 1 0 AAA domain RRM_6 PF14259.1 EMC79680.1 - 0.07 13.1 0.0 62 3.6 0.0 4.6 5 0 0 5 5 5 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_helicase PF00910.17 EMC79680.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Phage_NinH PF06322.6 EMC79680.1 - 0.16 11.6 1.0 16 5.2 0.0 3.5 3 0 0 3 3 3 0 Phage NinH protein AAA_17 PF13207.1 EMC79680.1 - 0.19 12.5 0.0 3.9 8.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain LBP_BPI_CETP_C PF02886.12 EMC79681.1 - 6.6e-29 100.8 0.6 6.6e-29 100.8 0.4 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 EMC79681.1 - 6.6e-27 93.8 0.6 3.3e-26 91.5 0.0 2.2 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain ubiquitin PF00240.18 EMC79682.1 - 6.7e-08 31.8 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EMC79682.1 - 0.00074 19.6 0.1 0.002 18.2 0.1 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain zf-C4H2 PF10146.4 EMC79682.1 - 3.5 7.6 8.0 3.8 7.4 4.6 1.5 1 1 1 2 2 2 0 Zinc finger-containing protein Pex14_N PF04695.8 EMC79682.1 - 7.4 6.6 8.9 2.9 7.9 3.2 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PB1 PF00564.19 EMC79683.1 - 1.4e-12 47.1 0.2 2.9e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ PF00595.19 EMC79683.1 - 7e-12 45.3 0.3 1.6e-11 44.1 0.2 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC79683.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 PDZ domain GFO_IDH_MocA PF01408.17 EMC79684.1 - 5.8e-15 55.8 0.0 1.6e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EMC79684.1 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.12 EMC79684.1 - 0.0014 18.4 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.15 EMC79684.1 - 0.0037 17.3 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.1 EMC79684.1 - 0.022 15.0 0.0 5.8 7.2 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain PDH PF02153.12 EMC79684.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase CIAPIN1 PF05093.8 EMC79686.1 - 2.7e-25 88.3 16.6 1.2e-22 79.8 10.2 2.7 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_31 PF13847.1 EMC79686.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC79686.1 - 3.1e-05 24.3 0.0 6.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC79686.1 - 0.00026 20.7 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC79686.1 - 0.011 16.1 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMC79686.1 - 0.013 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain COQ9 PF08511.6 EMC79687.1 - 1.2e-33 114.4 0.3 2e-33 113.7 0.2 1.4 1 0 0 1 1 1 1 COQ9 BicD PF09730.4 EMC79687.1 - 0.025 12.9 1.6 0.042 12.2 1.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Herpes_LMP2 PF07415.6 EMC79687.1 - 0.16 10.5 2.7 0.26 9.8 1.4 1.6 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein RNA_pol_A_bac PF01000.21 EMC79688.1 - 2.1e-40 137.3 0.0 3e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMC79688.1 - 3.7e-10 38.7 0.0 4.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IRS PF02174.12 EMC79689.1 - 2.9e-29 100.5 0.0 4.7e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Myosin_tail_1 PF01576.14 EMC79690.1 - 7e-13 47.2 71.1 4.8e-11 41.1 30.8 3.0 2 1 1 3 3 3 3 Myosin tail Filament PF00038.16 EMC79690.1 - 8.8e-05 22.1 58.7 0.018 14.5 0.4 3.3 2 1 1 3 3 3 3 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC79690.1 - 0.00066 19.4 48.4 0.18 11.5 1.8 4.6 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EMC79690.1 - 0.0041 16.1 20.6 0.0041 16.1 14.3 3.6 2 1 1 3 3 2 2 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 EMC79690.1 - 0.03 13.6 52.4 1.8 7.8 20.1 4.6 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EMC79690.1 - 0.033 13.3 7.1 0.31 10.1 1.2 3.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EMC79690.1 - 0.04 14.0 34.4 0.34 11.0 2.6 4.4 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EMC79690.1 - 0.067 13.0 64.4 0.23 11.2 8.5 4.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EMC79690.1 - 0.087 11.8 62.6 0.43 9.5 15.2 3.8 2 1 2 4 4 4 0 Autophagy protein Apg6 NPV_P10 PF05531.7 EMC79690.1 - 0.14 12.4 21.4 0.6 10.3 0.7 5.5 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 EMC79690.1 - 0.4 10.5 62.4 0.36 10.7 7.2 4.9 2 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Matrilin_ccoil PF10393.4 EMC79690.1 - 0.71 9.2 6.6 1.1 8.6 0.2 3.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin WEMBL PF05701.6 EMC79690.1 - 0.73 8.2 65.0 1 7.7 37.4 2.4 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Laminin_II PF06009.7 EMC79690.1 - 0.89 9.3 28.2 0.18 11.5 6.3 4.6 2 1 2 4 4 4 0 Laminin Domain II GAS PF13851.1 EMC79690.1 - 1.2 8.3 63.4 0.21 10.7 16.6 4.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EMC79690.1 - 1.7 9.0 47.2 2.5 8.5 3.8 5.6 2 1 3 5 5 5 0 Protein of unknown function (DUF972) BRE1 PF08647.6 EMC79690.1 - 9.8 6.2 53.0 0.92 9.5 0.3 4.9 2 1 3 5 5 4 0 BRE1 E3 ubiquitin ligase 7tm_2 PF00002.19 EMC79691.1 - 1.5e-31 109.3 19.0 2e-31 108.9 13.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 EMC79691.1 - 3.1e-13 49.5 3.9 7.6e-13 48.3 2.7 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Syndecan PF01034.15 EMC79691.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain 7tm_2 PF00002.19 EMC79692.1 - 4.4e-33 114.3 24.6 5.9e-33 113.9 17.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 EMC79692.1 - 1.4e-14 53.9 2.3 3.3e-14 52.6 1.6 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Transglut_core PF01841.14 EMC79693.1 - 0.00067 19.8 0.1 0.0021 18.2 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EMC79693.1 - 0.0029 16.8 0.0 0.0058 15.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like domain WD40 PF00400.27 EMC79694.1 - 8.7e-61 199.7 10.3 1.6e-13 49.9 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Katanin_con80 PF13925.1 EMC79694.1 - 4e-51 172.9 1.5 6.3e-51 172.3 1.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin Nucleoporin_N PF08801.6 EMC79694.1 - 4.5e-06 25.6 0.0 0.00017 20.4 0.0 2.7 1 1 1 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 EMC79694.1 - 0.053 11.6 0.9 8.3 4.4 0.0 3.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Kinesin PF00225.18 EMC79695.1 - 1.4e-107 359.2 0.0 1.6e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Zeta_toxin PF06414.7 EMC79695.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Enolase_C PF00113.17 EMC79695.1 - 0.075 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain CENP-F_leu_zip PF10473.4 EMC79696.1 - 0.001 18.9 17.9 0.0015 18.3 12.4 1.4 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoLp-III PF07464.6 EMC79696.1 - 0.0026 17.8 5.2 0.0031 17.5 3.6 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Atg14 PF10186.4 EMC79696.1 - 0.0031 16.4 9.1 0.0037 16.2 6.3 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Rho_Binding PF08912.6 EMC79696.1 - 0.0074 16.5 1.1 0.0074 16.5 0.8 3.2 3 1 0 3 3 3 1 Rho Binding DUF342 PF03961.8 EMC79696.1 - 0.011 14.2 6.3 0.012 14.0 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.6 EMC79696.1 - 0.036 13.9 2.2 0.29 11.0 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EMC79696.1 - 0.04 12.5 9.0 0.046 12.3 6.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EMC79696.1 - 0.06 11.1 4.6 0.065 11.0 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ring_hydroxyl_B PF00866.13 EMC79696.1 - 0.071 12.7 2.5 0.57 9.8 0.2 2.0 2 0 0 2 2 2 0 Ring hydroxylating beta subunit DUF3450 PF11932.3 EMC79696.1 - 0.095 11.9 12.3 0.38 9.9 4.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Filament PF00038.16 EMC79696.1 - 0.098 12.1 13.7 0.18 11.2 9.5 1.3 1 1 0 1 1 1 0 Intermediate filament protein Macoilin PF09726.4 EMC79696.1 - 0.19 9.9 10.9 0.2 9.9 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein AAA_13 PF13166.1 EMC79696.1 - 0.23 9.8 5.3 0.25 9.7 3.7 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EMC79696.1 - 0.26 10.2 11.4 0.34 9.8 7.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EMC79696.1 - 0.38 10.4 13.2 0.17 11.5 7.2 1.7 1 1 0 1 1 1 0 Mnd1 family GAS PF13851.1 EMC79696.1 - 0.41 9.8 12.2 0.87 8.7 2.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cauli_AT PF03233.8 EMC79696.1 - 0.46 10.1 2.5 0.58 9.8 1.7 1.1 1 0 0 1 1 1 0 Aphid transmission protein TMPIT PF07851.8 EMC79696.1 - 0.93 8.5 4.5 1.2 8.0 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein TBPIP PF07106.8 EMC79696.1 - 1.1 8.7 10.3 1 8.9 1.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG2 PF06148.6 EMC79696.1 - 1.2 9.0 8.4 1.2 9.0 3.9 2.1 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EMC79696.1 - 1.3 8.5 21.4 3 7.4 14.8 1.6 1 1 0 1 1 1 0 IncA protein Bap31 PF05529.7 EMC79696.1 - 1.7 8.0 7.5 8.4 5.8 5.2 1.9 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like FUSC PF04632.7 EMC79696.1 - 1.9 6.8 6.3 2.2 6.6 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 EMC79696.1 - 1.9 8.3 15.5 12 5.7 5.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Spc34 PF08657.5 EMC79696.1 - 2 7.9 10.0 3.2 7.3 6.9 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF2730 PF10805.3 EMC79696.1 - 2.1 8.1 7.5 7.7 6.3 3.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) ING PF12998.2 EMC79696.1 - 2.3 8.5 8.1 1.1 9.6 2.8 1.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Striatin PF08232.7 EMC79696.1 - 2.8 8.2 11.6 0.65 10.3 5.6 1.6 2 0 0 2 2 2 0 Striatin family Seryl_tRNA_N PF02403.17 EMC79696.1 - 2.9 7.9 10.4 1.1 9.2 2.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.5 EMC79696.1 - 3 7.7 17.0 0.041 13.7 4.1 2.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF724 PF05266.9 EMC79696.1 - 3.1 7.3 11.7 3.9 7.0 6.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4610 PF15384.1 EMC79696.1 - 3.5 7.0 6.2 3.8 6.9 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4610) ZapA PF05164.8 EMC79696.1 - 4.5 7.3 8.5 35 4.4 5.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapA Occludin_ELL PF07303.8 EMC79696.1 - 4.9 7.9 6.5 2 9.2 2.9 1.6 2 0 0 2 2 1 0 Occludin homology domain cNMP_binding PF00027.24 EMC79697.1 - 8.6e-15 54.3 0.0 2.9e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Borealin PF10512.4 EMC79699.1 - 0.013 15.3 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 zf-H2C2_2 PF13465.1 EMC79701.1 - 1.7e-61 201.6 145.2 8.2e-11 41.6 1.0 17.9 18 0 0 18 18 18 15 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79701.1 - 4.7e-57 187.0 154.0 3.8e-06 26.9 0.7 17.3 17 0 0 17 17 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79701.1 - 8.5e-40 132.1 132.6 0.00013 22.0 2.9 16.9 17 0 0 17 17 17 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79701.1 - 9.3e-24 82.9 84.2 0.0055 16.8 0.9 15.0 15 0 0 15 15 15 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC79701.1 - 1.4e-18 66.3 97.6 0.016 15.3 0.4 14.9 15 0 0 15 15 15 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC79701.1 - 1.1e-17 63.2 105.9 0.012 15.4 0.8 16.3 16 0 0 16 16 16 10 C2H2-type zinc finger BolA PF01722.13 EMC79701.1 - 2.3e-05 24.2 24.8 0.71 9.8 0.1 8.0 5 2 2 7 7 7 3 BolA-like protein Antimicrobial_3 PF08025.6 EMC79701.1 - 0.15 11.8 1.0 32 4.3 0.0 4.0 3 0 0 3 3 3 0 Spider antimicrobial peptide PAT1 PF09770.4 EMC79701.1 - 4.1 5.5 9.1 6.6 4.8 6.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HVSL PF09749.4 EMC79702.1 - 8.8e-45 152.5 0.0 1e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Peptidase_M10 PF00413.19 EMC79703.1 - 2e-40 138.0 0.1 2.5e-40 137.7 0.1 1.1 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC79703.1 - 1.7e-12 46.8 4.4 3.1e-07 30.0 0.3 2.8 2 0 0 2 2 2 2 Hemopexin Reprolysin_5 PF13688.1 EMC79703.1 - 0.021 14.7 0.1 0.028 14.3 0.1 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.6 EMC79703.1 - 0.024 14.3 0.0 0.063 13.0 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M54 Metallopep PF12044.3 EMC79703.1 - 0.03 12.7 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.1 EMC79703.1 - 0.06 13.4 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMC79703.1 - 0.082 13.4 0.6 0.14 12.6 0.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EMC79703.1 - 0.084 11.7 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 EMC79703.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF667 PF05018.8 EMC79704.1 - 5.2e-88 293.2 0.8 5.8e-88 293.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.20 EMC79706.1 - 2.2e-65 220.3 0.8 2.7e-65 220.1 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79706.1 - 1.9e-21 76.3 0.2 4e-21 75.2 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC79706.1 - 4.9e-10 39.5 0.0 3.3e-06 27.0 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC79706.1 - 0.0019 17.7 0.2 0.0047 16.5 0.1 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EMC79706.1 - 0.014 14.4 0.4 0.026 13.6 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.6 EMC79706.1 - 0.029 14.4 0.1 0.08 13.0 0.1 1.7 1 0 0 1 1 1 0 PAS fold YrbL-PhoP_reg PF10707.4 EMC79706.1 - 0.044 13.1 1.1 0.64 9.3 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF4201 PF13870.1 EMC79707.1 - 2.7e-33 114.8 32.6 4.1e-33 114.2 18.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Sugarporin_N PF11471.3 EMC79707.1 - 0.014 15.0 1.5 0.014 15.0 1.0 3.5 5 0 0 5 5 5 0 Maltoporin periplasmic N-terminal extension Astacin PF01400.19 EMC79707.1 - 0.033 13.5 0.1 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) PAS_10 PF13596.1 EMC79707.1 - 0.53 10.5 3.6 3.4 8.0 0.1 2.7 3 0 0 3 3 3 0 PAS domain NFRKB_winged PF14465.1 EMC79707.1 - 0.8 9.5 3.9 1.5 8.7 0.2 2.7 3 0 0 3 3 3 0 NFRKB Winged Helix-like ASL_C2 PF14698.1 EMC79707.1 - 2.3 8.3 4.6 3.3 7.8 0.4 2.9 2 1 0 2 2 2 0 Argininosuccinate lyase C-terminal DUF948 PF06103.6 EMC79707.1 - 8.9 6.2 14.4 0.79 9.6 0.9 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PEP-utilisers_N PF05524.8 EMC79707.1 - 9 6.1 9.3 0.64 9.8 0.3 2.7 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Ndr PF03096.9 EMC79708.1 - 5.7e-104 346.5 0.0 6.6e-104 346.3 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 EMC79708.1 - 6e-15 55.7 0.0 8.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC79708.1 - 0.0055 16.2 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UCR_TM PF02921.9 EMC79709.1 - 2.3e-24 85.3 3.6 3.4e-24 84.8 2.5 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EMC79709.1 - 9.7e-17 60.3 0.3 2.4e-16 59.0 0.2 1.7 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Isochorismatase PF00857.15 EMC79709.1 - 0.15 12.0 0.2 14 5.5 0.2 2.1 1 1 1 2 2 2 0 Isochorismatase family I-set PF07679.11 EMC79710.1 - 0.0037 17.0 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 EMC79710.1 - 0.0093 15.8 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain UPF0086 PF01868.11 EMC79711.1 - 1.7e-22 78.8 1.7 2.3e-21 75.2 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function UPF0086 FYVE PF01363.16 EMC79712.1 - 1.4e-18 66.5 7.3 2.7e-18 65.6 5.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EMC79712.1 - 7.2e-13 48.6 0.2 1.2e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 EMC79712.1 - 0.0028 17.5 8.7 0.0051 16.7 5.8 1.5 1 1 0 1 1 1 1 FYVE-type zinc finger PH_6 PF15406.1 EMC79712.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.1 EMC79712.1 - 0.091 13.0 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain RdgC PF04381.7 EMC79712.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC IBR PF01485.16 EMC79712.1 - 1.1 9.1 9.0 3.7 7.5 6.3 2.0 1 1 0 1 1 1 0 IBR domain OrfB_Zn_ribbon PF07282.6 EMC79712.1 - 1.5 8.5 7.0 3.2 7.4 4.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_4 PF14570.1 EMC79712.1 - 5.3 6.7 10.2 42 3.8 0.0 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2 PF00096.21 EMC79715.1 - 4.9e-06 26.5 14.3 0.45 10.9 3.4 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC79715.1 - 2.1e-05 24.5 0.0 2.1e-05 24.5 0.0 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC79715.1 - 7.5e-05 22.7 13.4 1.2 9.6 0.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger PH PF00169.24 EMC79716.1 - 1.1e-14 54.4 0.1 1.1e-14 54.4 0.1 4.3 5 1 0 5 5 5 1 PH domain PH_11 PF15413.1 EMC79716.1 - 0.0015 18.7 2.0 0.0015 18.7 1.4 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EMC79716.1 - 0.0026 17.6 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PI-PLC-X PF00388.14 EMC79717.1 - 9.3e-61 203.5 0.0 1.6e-60 202.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMC79717.1 - 9.9e-45 151.3 0.2 2e-44 150.3 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC79717.1 - 1.3e-21 76.4 1.2 1.9e-21 75.8 0.2 1.8 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EMC79717.1 - 1.3e-16 60.2 0.3 5.2e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 C2 domain NAD_binding_9 PF13454.1 EMC79720.1 - 0.099 12.4 0.7 2 8.1 0.1 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding PT PF04886.7 EMC79721.1 - 4.2e-05 22.7 5.1 0.0019 17.4 0.6 3.8 3 1 0 3 3 3 2 PT repeat DUF1777 PF08648.7 EMC79722.1 - 0.096 12.4 47.0 0.11 12.2 32.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF914 PF06027.7 EMC79723.1 - 6.8e-13 48.1 4.3 6.8e-12 44.8 1.5 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EMC79723.1 - 1.9e-10 40.8 18.7 4.7e-09 36.3 2.3 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EMC79723.1 - 1.2e-09 37.6 0.4 1.9e-09 36.9 0.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EMC79723.1 - 8.7e-08 31.9 9.9 0.00061 19.4 1.0 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EMC79723.1 - 3.7e-06 27.0 2.1 3.7e-06 27.0 1.5 2.9 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Bax1-I PF01027.15 EMC79723.1 - 5.5e-06 26.1 3.6 5.5e-06 26.1 2.5 2.2 1 1 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 UAA PF08449.6 EMC79723.1 - 9.1e-06 24.7 5.2 1.3e-05 24.2 3.6 1.1 1 0 0 1 1 1 1 UAA transporter family Mg_trans_NIPA PF05653.9 EMC79723.1 - 0.0031 16.5 1.1 0.0059 15.5 0.8 1.4 1 0 0 1 1 1 1 Magnesium transporter NIPA UPF0546 PF10639.4 EMC79723.1 - 0.29 10.9 5.5 1.7 8.4 0.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF814 PF05670.8 EMC79727.1 - 1.9e-26 91.7 0.1 2.2e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Acetyltransf_13 PF13880.1 EMC79728.1 - 8.5e-31 105.5 0.0 1.7e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EMC79728.1 - 2.3e-15 55.8 0.9 5.6e-15 54.6 0.6 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.1 EMC79728.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EMC79729.1 - 1.2e-40 139.3 0.0 1.6e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79729.1 - 7.7e-33 113.6 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMC79729.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.3 1 1 0 1 1 1 0 RIO1 family Neur_chan_memb PF02932.11 EMC79731.1 - 6e-89 298.0 5.8 5.5e-88 294.8 4.0 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC79731.1 - 5.2e-77 257.8 3.8 5.2e-77 257.8 2.6 1.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.4 EMC79731.1 - 0.0017 17.8 0.1 0.0017 17.8 0.1 1.6 2 0 0 2 2 2 1 Region of unknown function (DUF2417) BSP_II PF05432.6 EMC79731.1 - 0.021 14.0 5.8 0.031 13.5 4.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2890 PF11081.3 EMC79731.1 - 0.053 13.5 3.4 0.082 12.9 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) eIF3_subunit PF08597.5 EMC79731.1 - 0.09 12.3 5.5 0.18 11.3 3.8 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Myc_N PF01056.13 EMC79731.1 - 0.15 11.1 2.4 0.22 10.6 1.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EMC79731.1 - 1 8.8 9.1 2.3 7.7 6.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EMC79731.1 - 2.2 6.6 6.7 2.9 6.2 4.6 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 EMC79731.1 - 7.5 4.6 6.6 11 4.1 4.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein 7tm_1 PF00001.16 EMC79732.1 - 6.7e-42 143.3 22.7 6.7e-42 143.3 15.7 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC79732.1 - 6.7e-07 28.7 22.9 9.5e-07 28.2 15.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srt PF10321.4 EMC79732.1 - 0.00014 20.7 22.0 0.00017 20.4 15.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF2208 PF09973.4 EMC79732.1 - 0.005 16.1 7.1 0.03 13.5 0.6 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2208) Tmemb_18A PF09771.4 EMC79732.1 - 8 6.4 10.3 8 6.4 0.5 2.8 1 1 0 2 2 2 0 Transmembrane protein 188 Keratin_B2 PF01500.12 EMC79733.1 - 1.7 8.3 42.4 0.21 11.3 5.6 3.7 1 1 2 3 3 3 0 Keratin, high sulfur B2 protein BAH PF01426.13 EMC79734.1 - 6.8e-45 151.6 0.0 1.3e-22 79.7 0.0 2.4 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EMC79734.1 - 1.5e-39 135.0 0.0 7.6e-39 132.7 0.0 2.1 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain DNA_methylase PF00145.12 EMC79734.1 - 4e-35 121.5 0.0 5.4e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase zf-CXXC PF02008.15 EMC79734.1 - 4e-15 55.3 21.2 1.5e-14 53.5 14.7 2.1 1 0 0 1 1 1 1 CXXC zinc finger domain Laminin_G_2 PF02210.19 EMC79735.1 - 7.3e-08 32.5 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 EMC79735.1 - 0.00022 21.5 0.1 0.00077 19.7 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 EMC79735.1 - 0.05 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain OLF PF02191.11 EMC79736.1 - 1e-93 313.1 2.7 1.4e-93 312.8 1.9 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 EMC79736.1 - 2.9e-49 165.0 3.9 7e-48 160.5 0.5 3.1 3 0 0 3 3 3 1 Neurogenesis glycoprotein Lactonase PF10282.4 EMC79736.1 - 0.13 11.3 1.1 4.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Atg8 PF02991.11 EMC79737.1 - 1.6e-34 118.0 0.1 1.7e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMC79737.1 - 2.4e-05 24.4 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Lectin_C PF00059.16 EMC79738.1 - 4.9e-21 75.3 6.1 5.4e-21 75.2 4.2 1.0 1 0 0 1 1 1 1 Lectin C-type domain LIM PF00412.17 EMC79740.1 - 1.7e-30 104.8 22.7 6.1e-16 58.2 4.4 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 EMC79740.1 - 4.7e-18 64.5 2.6 1.1e-17 63.4 1.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79740.1 - 5.5e-05 22.7 0.2 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain CHCH PF06747.8 EMC79741.1 - 7.4e-07 28.9 4.4 6.9e-05 22.6 0.5 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 EMC79741.1 - 0.0002 21.0 5.8 0.48 10.2 0.1 3.0 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 EMC79741.1 - 0.0016 18.4 3.1 0.041 13.9 0.6 2.3 1 1 1 2 2 2 1 GCK domain COX17 PF05051.8 EMC79741.1 - 0.02 14.9 2.1 11 6.1 0.0 3.1 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) SRCR PF00530.13 EMC79741.1 - 0.059 13.7 2.4 0.36 11.1 1.7 2.0 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain Pet191_N PF10203.4 EMC79741.1 - 0.064 13.3 6.7 0.33 11.0 2.0 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DD_K PF12121.3 EMC79741.1 - 0.072 13.0 1.2 0.12 12.2 0.8 1.4 1 0 0 1 1 1 0 Dermaseptin DUF753 PF05444.7 EMC79741.1 - 0.099 12.5 3.1 0.18 11.6 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF753) UCR_hinge PF02320.11 EMC79741.1 - 0.17 11.8 3.3 2.5 8.1 0.1 2.9 1 1 2 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EMC79741.1 - 0.22 11.3 3.5 10 6.0 0.1 2.7 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0203) NDUF_B7 PF05676.8 EMC79741.1 - 2.2 7.7 6.7 0.78 9.2 0.5 2.3 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) E1-E2_ATPase PF00122.15 EMC79742.1 - 0.001 18.1 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase DUF2464 PF10240.4 EMC79743.1 - 1.1e-06 28.2 0.0 5.6e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2464) MIS13 PF08202.6 EMC79744.1 - 1.1e-19 70.6 3.3 8.9e-19 67.6 2.3 1.9 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Ribosomal_L39 PF00832.15 EMC79744.1 - 0.052 13.0 0.9 0.052 13.0 0.6 1.9 2 0 0 2 2 2 0 Ribosomal L39 protein Lsr2 PF11774.3 EMC79744.1 - 0.071 13.0 0.7 3.1 7.7 0.3 2.9 2 1 1 3 3 3 0 Lsr2 PBC PF03792.8 EMC79745.1 - 9.3e-88 292.9 0.1 1.3e-87 292.5 0.1 1.2 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 EMC79745.1 - 1.7e-18 65.9 0.5 3.7e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC79745.1 - 2.3e-15 55.9 0.1 1.8e-14 53.1 0.0 2.4 3 0 0 3 3 3 1 Homeobox KN domain DUF1319 PF07028.6 EMC79745.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Homez PF11569.3 EMC79745.1 - 0.016 14.2 0.0 0.042 12.8 0.0 1.7 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 EMC79745.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sec15 PF04091.7 EMC79745.1 - 0.021 14.1 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like HTH_19 PF12844.2 EMC79745.1 - 0.028 14.4 0.1 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.8 EMC79745.1 - 0.048 13.0 0.2 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain NUC130_3NT PF08158.7 EMC79745.1 - 0.14 12.4 0.4 7.8 6.8 0.0 3.2 3 1 0 3 3 3 0 NUC130/3NT domain MADF_DNA_bdg PF10545.4 EMC79745.1 - 5.3 7.3 5.8 24 5.2 0.1 3.0 1 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 7tm_1 PF00001.16 EMC79746.1 - 6.3e-35 120.5 24.2 8.4e-35 120.1 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC79746.1 - 1.3e-11 44.1 23.6 1.7e-11 43.7 16.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RhoGAP PF00620.22 EMC79747.1 - 5.2e-40 136.5 0.2 1.1e-38 132.2 0.0 2.8 2 1 0 2 2 2 1 RhoGAP domain C1_1 PF00130.17 EMC79747.1 - 6e-05 22.6 11.3 6e-05 22.6 7.9 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.18 EMC79747.1 - 0.011 15.9 0.0 0.011 15.9 0.0 3.0 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain IF-2B PF01008.12 EMC79747.1 - 0.089 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family Cortex-I_coil PF09304.5 EMC79747.1 - 3.9 7.5 16.8 0.13 12.3 3.7 3.0 2 1 1 3 3 3 0 Cortexillin I, coiled coil AMP-binding PF00501.23 EMC79748.1 - 8.9e-74 248.3 0.0 1.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC79748.1 - 2e-07 31.8 0.1 4.2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HHH_3 PF12836.2 EMC79749.1 - 7.7e-42 141.0 0.2 1.5e-20 72.9 0.1 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.18 EMC79749.1 - 1.6e-17 62.0 0.1 2.4e-06 26.9 0.0 3.9 4 0 0 4 4 4 3 Helix-hairpin-helix motif HHH_5 PF14520.1 EMC79749.1 - 4.8e-09 36.2 0.0 1.8e-06 28.0 0.0 3.6 2 1 1 3 3 3 2 Helix-hairpin-helix domain Exo_endo_phos PF03372.18 EMC79749.1 - 5.5e-09 36.3 0.1 8.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_2 PF12826.2 EMC79749.1 - 5.9e-09 35.6 0.1 0.005 16.6 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_6 PF14579.1 EMC79749.1 - 3.3e-08 33.4 0.0 0.00021 21.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SK PF03934.8 EMC79749.1 - 3.4e-08 32.9 0.0 0.0018 17.5 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K Exo_endo_phos_2 PF14529.1 EMC79749.1 - 0.00074 19.1 0.6 0.0023 17.5 0.4 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase PsbU PF06514.6 EMC79749.1 - 0.0018 18.0 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) DUF1704 PF08014.6 EMC79750.1 - 2.5e-14 53.0 0.1 3.2e-13 49.4 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF1704) GN3L_Grn1 PF08701.6 EMC79750.1 - 0.0045 16.8 7.9 0.0098 15.7 5.5 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase Anillin PF08174.6 EMC79751.1 - 2.4e-22 79.4 0.2 8.9e-22 77.6 0.2 2.1 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EMC79751.1 - 2.3e-15 56.6 0.1 9.9e-15 54.6 0.1 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC79751.1 - 0.00041 20.5 0.1 0.002 18.3 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain Lipase_GDSL PF00657.17 EMC79752.1 - 3.1e-14 53.3 0.0 4.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SapB_2 PF03489.12 EMC79752.1 - 0.00041 20.3 1.2 0.00092 19.1 0.3 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 2 Cu-binding_MopE PF11617.3 EMC79752.1 - 0.006 16.3 3.1 0.02 14.6 2.1 1.9 1 1 0 1 1 1 1 Protein metal binding site DUF3361 PF11841.3 EMC79753.1 - 2.1e-72 242.0 2.7 5.1e-72 240.8 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 EMC79753.1 - 4e-49 166.4 0.6 7.7e-49 165.4 0.4 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family FERM_N PF09379.5 EMC79753.1 - 0.03 14.3 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 FERM N-terminal domain 7tm_1 PF00001.16 EMC79754.1 - 2.3e-11 43.3 25.7 2.9e-11 43.0 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3493 PF11998.3 EMC79754.1 - 0.43 10.4 8.9 1.5 8.7 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) 7tm_1 PF00001.16 EMC79755.1 - 1e-09 37.8 24.0 2.7e-09 36.5 16.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NDK PF00334.14 EMC79756.1 - 4.8e-102 337.1 0.1 1.1e-40 138.5 0.1 3.4 2 1 1 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.15 EMC79756.1 - 5.3e-11 42.1 0.2 1.4e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EMC79756.1 - 0.00022 20.9 0.1 0.00064 19.4 0.0 1.8 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC79756.1 - 0.0019 17.7 0.1 0.0043 16.6 0.1 1.6 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EMC79756.1 - 0.023 14.8 0.0 0.24 11.5 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin-like Glutaredoxin PF00462.19 EMC79756.1 - 0.1 12.5 0.0 0.47 10.4 0.0 2.1 1 0 0 1 1 1 0 Glutaredoxin Fz PF01392.17 EMC79758.1 - 8.1e-22 77.7 2.1 5.3e-10 39.6 0.5 2.5 1 1 1 2 2 2 2 Fz domain NTR PF01759.16 EMC79758.1 - 1.4e-16 60.0 3.3 2.7e-16 59.1 0.3 2.2 1 1 1 2 2 2 1 UNC-6/NTR/C345C module MENTAL PF10457.4 EMC79759.1 - 9.9e-74 246.6 5.3 1.2e-73 246.3 3.7 1.1 1 0 0 1 1 1 1 Cholesterol-capturing domain DNA_mis_repair PF01119.14 EMC79760.1 - 6.4e-34 115.9 0.2 1.2e-33 115.1 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMC79760.1 - 9e-15 54.5 0.0 2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC79760.1 - 1.6e-11 43.8 0.0 4.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 EMC79761.1 - 2.8e-06 26.8 0.1 6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EMC79761.1 - 0.0033 17.2 0.2 0.41 10.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC79761.1 - 0.0041 17.2 0.2 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC79761.1 - 0.019 15.3 0.2 0.72 10.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC79761.1 - 0.024 14.5 0.2 0.19 11.6 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC79761.1 - 0.06 13.5 0.1 3.3 8.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2122 PF09895.4 EMC79761.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) Ank_4 PF13637.1 EMC79762.1 - 1.8e-07 31.4 0.1 0.0034 17.8 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) UvrD_C_2 PF13538.1 EMC79762.1 - 8.3e-07 29.0 0.1 0.035 14.2 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Ank_2 PF12796.2 EMC79762.1 - 9.8e-07 29.0 0.0 1.2e-05 25.5 0.0 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) UvrD-helicase PF00580.16 EMC79762.1 - 1.2e-06 28.0 0.9 1.2e-06 28.0 0.6 3.8 3 2 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EMC79762.1 - 1.3e-05 24.8 0.0 1.3e-05 24.8 0.0 5.2 4 1 0 4 4 4 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.22 EMC79762.1 - 0.038 14.2 0.7 0.15 12.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Clathrin PF00637.15 EMC79762.1 - 0.061 12.9 22.8 0.11 12.1 2.8 5.1 5 1 1 6 6 6 0 Region in Clathrin and VPS Ank PF00023.25 EMC79762.1 - 0.082 12.7 0.0 6.3 6.8 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat TPR_8 PF13181.1 EMC79762.1 - 8.7 6.3 10.9 41 4.2 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.1 EMC79763.1 - 4.8e-20 70.8 0.1 9.7e-16 57.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC79763.1 - 3e-17 61.7 0.5 4.9e-15 54.6 0.1 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EMC79763.1 - 4e-17 61.4 0.2 2.1e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EMC79763.1 - 9.2e-10 38.1 9.5 9.2e-10 38.1 6.6 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DHHC PF01529.15 EMC79763.1 - 0.0027 17.1 4.1 0.0049 16.2 2.8 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4206 PF13901.1 EMC79763.1 - 0.0034 16.9 3.3 0.0063 16.0 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) RNA_POL_M_15KD PF02150.11 EMC79763.1 - 0.1 12.3 1.3 0.21 11.2 0.9 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit C1_3 PF07649.7 EMC79763.1 - 0.37 10.8 4.7 1.7 8.7 3.3 2.2 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 EMC79763.1 - 0.44 10.2 8.1 1 9.1 5.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EMC79763.1 - 7.4 6.6 9.7 20 5.2 6.7 1.7 1 0 0 1 1 1 0 RING-like domain C1_2 PF03107.11 EMC79763.1 - 9.9 6.3 7.9 6.1 7.0 2.7 2.8 3 0 0 3 3 3 0 C1 domain R3H PF01424.17 EMC79764.1 - 2.5e-13 49.4 0.1 8.1e-13 47.8 0.0 2.0 2 0 0 2 2 2 1 R3H domain MIP-T3 PF10243.4 EMC79765.1 - 6.7 5.0 36.6 8.5 4.7 25.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 7tm_4 PF13853.1 EMC79767.1 - 1.2e-53 180.8 14.7 1.2e-53 180.8 9.7 1.4 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC79767.1 - 2e-14 53.3 14.3 1.4e-10 40.7 0.1 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 EMC79767.1 - 0.89 9.5 2.8 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) EGF_CA PF07645.10 EMC79768.1 - 1.1e-19 70.0 39.6 8.8e-11 41.6 5.3 6.1 4 2 1 5 5 5 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 EMC79768.1 - 9.8e-11 41.5 66.6 0.0004 20.4 5.9 5.6 3 2 1 5 5 5 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EMC79768.1 - 6.1e-10 38.8 22.5 3.7e-08 33.1 7.3 6.2 4 3 2 6 6 6 3 EGF domain EGF PF00008.22 EMC79768.1 - 1.5e-09 37.5 69.8 0.0039 17.1 4.3 6.2 4 2 2 6 6 6 4 EGF-like domain cEGF PF12662.2 EMC79768.1 - 3.2e-08 33.0 39.9 0.0016 18.0 0.9 6.2 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.2 EMC79768.1 - 2 8.2 51.1 0.11 12.2 2.6 5.7 5 0 0 5 5 5 0 MSP1 EGF domain 1 Thymosin PF01290.15 EMC79770.1 - 2.9e-24 84.3 7.4 3.1e-24 84.2 5.2 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.15 EMC79770.1 - 0.00023 20.6 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 WH2 motif Integrin_b_cyt PF08725.6 EMC79770.1 - 0.2 11.0 0.8 0.23 10.8 0.6 1.2 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain LRR_8 PF13855.1 EMC79771.1 - 2.6e-73 241.6 86.2 4.5e-11 42.3 3.9 15.0 9 4 6 15 15 15 15 Leucine rich repeat LRR_4 PF12799.2 EMC79771.1 - 9.8e-49 162.2 94.4 1.3e-06 27.8 1.8 16.3 8 4 8 17 17 17 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC79771.1 - 1.7e-27 91.1 85.5 0.28 11.3 0.4 23.1 23 4 3 26 26 26 12 Leucine Rich Repeat TIR PF01582.15 EMC79771.1 - 3e-20 72.0 0.4 5e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.1 EMC79771.1 - 6.1e-14 51.8 21.3 1.7e-05 24.5 0.1 6.5 5 2 0 5 5 5 3 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC79771.1 - 3.1e-12 44.5 65.5 3.3 8.3 0.2 20.4 21 0 0 21 21 21 4 Leucine rich repeat LRR_9 PF14580.1 EMC79771.1 - 9.5e-05 22.0 25.4 0.65 9.5 2.2 7.3 4 2 4 8 8 8 3 Leucine-rich repeat TIR_2 PF13676.1 EMC79771.1 - 0.00019 21.5 0.1 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 EMC79771.1 - 0.0028 17.5 85.5 2.8 8.2 0.1 19.7 17 3 4 21 21 21 4 Leucine Rich repeat LRRNT PF01462.13 EMC79771.1 - 0.003 16.9 0.1 0.003 16.9 0.1 4.6 6 0 0 6 6 6 1 Leucine rich repeat N-terminal domain Pribosyl_synth PF14572.1 EMC79772.1 - 1e-44 152.4 1.9 3.1e-37 128.1 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMC79772.1 - 2e-41 140.3 0.2 9.4e-41 138.1 0.0 2.1 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMC79772.1 - 2.6e-10 40.1 0.9 1.1e-09 38.1 0.4 2.1 1 1 1 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.1 EMC79772.1 - 0.00016 20.9 0.1 0.00027 20.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FERM_M PF00373.13 EMC79773.1 - 9.6e-22 77.4 0.1 3e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.19 EMC79773.1 - 1e-10 41.6 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) WW PF00397.21 EMC79773.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 WW domain PDZ_2 PF13180.1 EMC79773.1 - 8.6e-05 22.3 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain FERM_N PF09379.5 EMC79773.1 - 0.012 15.6 0.2 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 FERM N-terminal domain MRG PF05712.8 EMC79774.1 - 9.5e-68 226.9 0.3 1.3e-67 226.4 0.2 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EMC79774.1 - 5e-05 22.9 0.4 0.00012 21.7 0.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EMC79774.1 - 0.054 13.1 0.2 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2828 PF11443.3 EMC79774.1 - 0.098 10.8 0.9 0.13 10.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ABC_tran PF00005.22 EMC79777.1 - 1.7e-33 115.7 0.0 2.2e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMC79777.1 - 3.2e-07 29.7 0.0 6.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC79777.1 - 8.9e-05 22.5 0.0 0.28 11.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 EMC79777.1 - 0.0002 22.1 0.1 0.00024 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EMC79777.1 - 0.00048 18.8 0.2 0.0023 16.5 0.1 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.1 EMC79777.1 - 0.00065 19.8 0.3 0.0073 16.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMC79777.1 - 0.001 18.7 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMC79777.1 - 0.0011 18.9 1.3 0.0056 16.6 0.9 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EMC79777.1 - 0.0023 17.3 0.9 0.58 9.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EMC79777.1 - 0.0046 16.8 0.9 0.058 13.3 0.7 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EMC79777.1 - 0.0095 15.4 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EMC79777.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC79777.1 - 0.02 14.3 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 EMC79777.1 - 0.025 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.9 EMC79777.1 - 0.037 13.7 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EMC79777.1 - 0.04 14.1 0.0 4.2 7.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EMC79777.1 - 0.046 12.9 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3987 PF13148.1 EMC79777.1 - 0.05 12.1 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF87 PF01935.12 EMC79777.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EMC79777.1 - 0.055 12.8 0.6 2.1 7.7 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 EMC79777.1 - 0.12 12.3 0.2 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMC79777.1 - 0.17 11.7 0.3 0.23 11.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain ASC PF00858.19 EMC79778.1 - 1.1e-121 406.5 0.0 3.4e-75 253.3 0.0 2.0 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel Pkinase PF00069.20 EMC79779.1 - 1.8e-21 76.4 0.1 4e-18 65.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79779.1 - 1.9e-10 40.2 0.0 8e-09 34.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Sugar_tr PF00083.19 EMC79781.1 - 1.8e-19 69.6 19.4 4.6e-17 61.7 2.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC79781.1 - 1.4e-16 60.1 32.6 1.5e-15 56.7 22.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC79782.1 - 1.7e-28 99.4 22.5 2.2e-28 99.0 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC79782.1 - 1.8e-28 99.3 28.7 2.2e-28 99.0 19.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily eIF-5a PF01287.15 EMC79782.1 - 0.018 14.9 0.3 0.033 14.1 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RhoGEF PF00621.15 EMC79784.1 - 9.9e-47 159.1 2.4 9.9e-47 159.1 1.7 1.8 2 1 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 EMC79784.1 - 1.4e-12 46.9 0.2 3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC79784.1 - 2.2e-10 39.7 1.8 4.9e-10 38.6 1.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC79784.1 - 1.4e-09 37.2 0.1 3.5e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC79784.1 - 2.3e-06 27.7 0.2 4.9e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 PH domain CSD PF00313.17 EMC79784.1 - 0.058 13.1 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain SH3_3 PF08239.6 EMC79784.1 - 0.087 13.0 0.3 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase_Tyr PF07714.12 EMC79786.1 - 8.1e-101 336.4 0.0 1.4e-100 335.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.11 EMC79786.1 - 7.9e-55 182.7 4.1 1.8e-18 66.1 0.0 5.9 5 1 0 5 5 5 5 Immunoglobulin I-set domain Pkinase PF00069.20 EMC79786.1 - 3.1e-45 154.3 0.0 5.4e-31 107.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.1 EMC79786.1 - 5.5e-40 135.3 9.1 4.5e-09 36.3 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 EMC79786.1 - 2.9e-33 114.1 12.7 4.9e-09 36.5 0.0 6.9 5 2 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 EMC79786.1 - 1.2e-24 86.1 3.9 1.1e-05 25.4 0.0 7.2 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.12 EMC79786.1 - 5.6e-18 64.8 12.9 5.9e-05 22.9 0.6 6.5 5 3 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC79786.1 - 2.5e-07 30.5 2.5 0.015 15.1 0.0 4.3 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC79786.1 - 1e-05 24.0 0.3 0.27 9.4 0.0 3.6 2 1 0 3 3 3 2 Alphaherpesvirus glycoprotein E BiPBP_C PF06832.7 EMC79786.1 - 0.065 13.1 0.0 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Caudal_act PF04731.7 EMC79787.1 - 8.5e-52 175.1 15.7 8.5e-52 175.1 10.9 1.6 2 0 0 2 2 2 1 Caudal like protein activation region Homeobox PF00046.24 EMC79787.1 - 2.7e-20 71.7 5.8 4.3e-20 71.0 4.0 1.3 1 0 0 1 1 1 1 Homeobox domain Mito_fiss_reg PF05308.6 EMC79787.1 - 0.0044 16.4 4.0 0.0044 16.4 2.8 1.6 2 0 0 2 2 2 1 Mitochondrial fission regulator Homeobox_KN PF05920.6 EMC79787.1 - 0.084 12.5 1.3 0.17 11.6 0.9 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 EMC79787.1 - 0.094 11.7 0.1 0.21 10.6 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Caudal_act PF04731.7 EMC79788.1 - 2.3e-49 167.2 13.6 3.3e-49 166.7 9.4 1.2 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 EMC79788.1 - 8.5e-22 76.5 3.0 1.3e-21 75.9 2.1 1.3 1 0 0 1 1 1 1 Homeobox domain TFIIA PF03153.8 EMC79788.1 - 0.019 14.9 0.1 0.023 14.6 0.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Homeobox_KN PF05920.6 EMC79788.1 - 0.025 14.2 0.6 0.05 13.3 0.4 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 EMC79788.1 - 0.12 11.4 0.1 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Erf4 PF10256.4 EMC79789.1 - 6.8e-26 90.4 0.0 9.7e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Fip1 PF05182.8 EMC79790.1 - 1e-26 91.8 0.7 1.6e-26 91.3 0.5 1.3 1 0 0 1 1 1 1 Fip1 motif PDZ PF00595.19 EMC79791.1 - 7e-64 211.9 4.3 1.8e-16 60.0 0.1 4.2 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC79791.1 - 5.2e-23 80.7 0.7 0.00054 19.7 0.0 4.4 4 0 0 4 4 4 4 PDZ domain Tricorn_PDZ PF14685.1 EMC79791.1 - 6.7e-06 25.8 0.1 7.4 6.4 0.0 4.4 4 0 0 4 4 4 3 Tricorn protease PDZ domain zf-TRAF PF02176.13 EMC79791.1 - 0.012 15.9 1.2 0.031 14.6 0.8 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger SRP-alpha_N PF04086.8 EMC79791.1 - 0.057 12.8 1.3 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PPDFL PF15060.1 EMC79791.1 - 0.095 12.7 1.8 1.9 8.5 0.3 2.6 2 0 0 2 2 2 0 Differentiation and proliferation regulator Ras PF00071.17 EMC79792.1 - 5.1e-30 103.9 0.0 1.9e-29 102.1 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC79792.1 - 9e-16 58.4 0.0 1.8e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC79792.1 - 0.00066 18.9 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC79792.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC79792.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit 7tm_1 PF00001.16 EMC79793.1 - 3.1e-31 108.4 12.2 3.7e-31 108.1 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.11 EMC79794.1 - 1.6e-11 43.5 3.3 1.7e-11 43.4 2.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 EMC79795.1 - 5e-15 55.0 7.5 8.1e-15 54.3 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC79795.1 - 1.5e-09 37.8 2.6 2.8e-09 36.9 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC79795.1 - 1.6e-06 27.6 7.6 2.6e-06 26.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC79795.1 - 8.8e-06 25.2 4.2 1.3e-05 24.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC79795.1 - 1.3e-05 24.7 6.4 2.1e-05 24.1 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC79795.1 - 3.7e-05 23.4 1.4 7.9e-05 22.4 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMC79795.1 - 6.7e-05 22.8 7.5 0.00011 22.1 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMC79795.1 - 0.048 13.2 4.4 0.085 12.4 3.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EMC79795.1 - 0.054 13.0 2.2 0.1 12.1 1.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 EMC79795.1 - 1.1 9.3 7.0 1.9 8.5 4.8 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 EMC79795.1 - 1.2 9.2 7.5 2.2 8.3 5.2 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EMC79795.1 - 1.7 8.6 5.2 6.1 6.8 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain ABC_tran PF00005.22 EMC79797.1 - 2.6e-35 121.6 0.0 6.6e-35 120.3 0.0 1.7 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 EMC79797.1 - 2.8e-28 99.1 10.5 3.6e-28 98.7 7.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EMC79797.1 - 1.9e-05 24.0 0.2 0.0086 15.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC79797.1 - 2e-05 24.6 0.0 0.0029 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMC79797.1 - 0.0008 18.8 1.8 0.00083 18.8 0.1 1.9 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EMC79797.1 - 0.0012 19.5 0.0 0.004 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 EMC79797.1 - 0.0044 16.8 0.8 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EMC79797.1 - 0.016 15.3 0.5 0.12 12.5 0.1 2.5 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMC79797.1 - 0.017 15.4 0.1 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EMC79797.1 - 0.023 14.6 1.9 0.13 12.1 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 EMC79797.1 - 0.023 14.6 0.1 0.12 12.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EMC79797.1 - 0.024 14.5 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMC79797.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMC79797.1 - 0.034 13.5 0.1 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EMC79797.1 - 0.048 12.8 0.0 0.15 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EMC79797.1 - 0.081 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ATP-synt_ab PF00006.20 EMC79797.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EMC79797.1 - 0.14 11.7 0.1 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPRTase PF14681.1 EMC79798.1 - 9.9e-46 155.5 0.0 1.2e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMC79798.1 - 2.7e-05 23.8 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 14-3-3 PF00244.15 EMC79798.1 - 0.074 12.1 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein FGF PF00167.13 EMC79799.1 - 5.5e-32 110.0 0.1 6.3e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor SIR2 PF02146.12 EMC79799.1 - 0.1 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Sir2 family Helicase_C PF00271.26 EMC79800.1 - 5.3e-16 58.2 0.1 6.2e-15 54.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1689 PF07954.6 EMC79800.1 - 0.011 15.5 1.3 0.2 11.5 0.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) SNF2_N PF00176.18 EMC79801.1 - 3.3e-34 118.0 0.0 3.5e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain 7tm_1 PF00001.16 EMC79802.1 - 1.3e-59 201.4 24.6 1.7e-59 201.0 17.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC79802.1 - 1.6e-10 40.5 26.8 2.2e-10 40.1 18.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Rifin_STEVOR PF02009.11 EMC79802.1 - 0.34 10.5 0.0 0.34 10.5 0.0 2.1 3 0 0 3 3 3 0 Rifin/stevor family Hexokinase_2 PF03727.11 EMC79803.1 - 1e-206 683.0 2.1 1.7e-105 351.6 0.3 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EMC79803.1 - 2.2e-172 569.3 0.5 2.4e-87 291.5 0.1 2.3 2 0 0 2 2 2 2 Hexokinase CSD PF00313.17 EMC79803.1 - 0.01 15.5 0.0 0.41 10.4 0.0 2.7 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Sec23_helical PF04815.10 EMC79803.1 - 0.019 14.3 0.0 0.052 12.9 0.0 1.8 1 0 0 1 1 1 0 Sec23/Sec24 helical domain DUF1997 PF09366.5 EMC79803.1 - 0.041 13.6 0.0 3.5 7.3 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1997) Hexokinase_2 PF03727.11 EMC79804.1 - 1.5e-200 662.9 2.6 4.6e-103 343.6 0.3 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EMC79804.1 - 1.9e-153 507.4 0.0 1.4e-81 272.7 0.0 2.3 2 0 0 2 2 2 2 Hexokinase F420_ligase PF01996.11 EMC79804.1 - 0.03 13.3 0.1 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase Pyridoxal_deC PF00282.14 EMC79804.1 - 0.051 12.0 0.2 2.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain SUV3_C PF12513.3 EMC79805.1 - 2.9e-18 65.0 0.0 8.6e-18 63.5 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EMC79805.1 - 1.2e-12 47.4 0.0 3.9e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Vps26 PF03643.10 EMC79806.1 - 5e-133 442.0 4.5 5.8e-133 441.8 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EMC79806.1 - 0.021 14.6 1.2 1.4 8.7 0.0 3.5 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMC79806.1 - 0.079 13.0 0.1 0.27 11.3 0.1 2.1 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Serglycin PF04360.7 EMC79807.1 - 4e-21 75.3 0.1 4.3e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Serglycin GUCT PF08152.7 EMC79808.1 - 2.6e-30 104.2 0.0 7.8e-30 102.7 0.0 1.8 2 0 0 2 2 2 1 GUCT (NUC152) domain Helicase_C PF00271.26 EMC79808.1 - 4e-25 87.4 0.0 9.5e-25 86.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CPL PF08144.6 EMC79808.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 CPL (NUC119) domain FTR PF01913.13 EMC79808.1 - 0.024 14.3 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase DBC1 PF14443.1 EMC79809.1 - 1.4e-57 192.6 0.0 1.4e-57 192.6 0.0 2.4 2 0 0 2 2 2 1 DBC1 S1-like PF14444.1 EMC79809.1 - 1.1e-34 117.9 0.8 1.9e-34 117.1 0.5 1.4 1 0 0 1 1 1 1 S1-like SAP PF02037.22 EMC79809.1 - 4.1e-08 32.5 1.9 4.1e-08 32.5 1.3 2.3 2 0 0 2 2 2 1 SAP domain MIP-T3 PF10243.4 EMC79809.1 - 0.0013 17.2 41.1 0.0013 17.2 28.5 4.4 5 0 0 5 5 5 1 Microtubule-binding protein MIP-T3 Tet_JBP PF12851.2 EMC79810.1 - 1.2e-49 167.9 0.1 4e-49 166.1 0.1 1.9 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily zf-CXXC PF02008.15 EMC79810.1 - 6e-05 22.7 28.8 6e-05 22.7 20.0 2.7 2 0 0 2 2 2 1 CXXC zinc finger domain Mito_carr PF00153.22 EMC79811.1 - 1.1e-71 236.5 6.9 5.5e-24 83.7 0.8 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dna2 PF08696.6 EMC79812.1 - 7.6e-71 237.7 0.4 1.7e-70 236.5 0.3 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EMC79812.1 - 9.2e-42 142.6 3.0 9.6e-42 142.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMC79812.1 - 1.5e-38 132.7 4.3 1.3e-36 126.3 0.3 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMC79812.1 - 3.2e-13 49.7 0.0 1.6e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 EMC79812.1 - 7.5e-12 45.1 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 EMC79812.1 - 7e-08 32.1 0.1 1.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EMC79812.1 - 5.5e-05 22.8 1.1 0.094 12.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.12 EMC79812.1 - 0.00014 21.8 5.2 0.013 15.4 0.9 3.6 2 1 0 2 2 2 1 Domain of unknown function DUF83 CbiA PF01656.18 EMC79812.1 - 0.00017 21.0 0.0 0.00044 19.7 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 EMC79812.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EMC79812.1 - 0.0059 16.6 0.2 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.11 EMC79812.1 - 0.0081 15.4 1.4 0.028 13.6 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein AAA_25 PF13481.1 EMC79812.1 - 0.0081 15.5 0.1 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EMC79812.1 - 0.0084 15.8 0.1 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B UvrD-helicase PF00580.16 EMC79812.1 - 0.012 14.9 4.1 0.016 14.5 0.0 2.6 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain DUF853 PF05872.7 EMC79812.1 - 0.013 13.8 0.1 0.021 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) cobW PF02492.14 EMC79812.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EMC79812.1 - 0.017 15.3 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMC79812.1 - 0.024 14.1 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.9 EMC79812.1 - 0.046 13.3 0.0 0.17 11.4 0.0 2.0 2 1 0 2 2 2 0 Helicase AAA_17 PF13207.1 EMC79812.1 - 0.049 14.4 0.4 0.15 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain ResIII PF04851.10 EMC79812.1 - 0.089 12.6 0.4 0.4 10.4 0.2 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EMC79812.1 - 0.097 12.9 6.4 0.11 12.7 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 EMC79812.1 - 0.099 12.7 0.1 0.46 10.6 0.1 2.1 1 0 0 1 1 1 0 AAA domain RUN PF02759.14 EMC79813.1 - 2e-28 98.7 0.0 2e-28 98.7 0.0 2.3 2 1 0 2 2 2 1 RUN domain FYVE PF01363.16 EMC79813.1 - 1.5e-20 72.8 9.0 1.5e-20 72.8 6.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger DUF972 PF06156.8 EMC79813.1 - 0.002 18.4 7.6 0.002 18.4 5.3 4.7 2 1 2 4 4 4 1 Protein of unknown function (DUF972) IBR PF01485.16 EMC79813.1 - 0.21 11.5 7.9 0.63 9.9 5.5 1.9 1 0 0 1 1 1 0 IBR domain zf-RING_5 PF14634.1 EMC79813.1 - 0.29 10.8 13.6 0.57 9.9 9.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain ADK_lid PF05191.9 EMC79813.1 - 0.33 10.6 7.4 0.093 12.4 2.5 2.1 2 1 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_2 PF14445.1 EMC79813.1 - 1.5 8.8 5.4 5.2 7.1 3.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 C1_1 PF00130.17 EMC79813.1 - 2 8.2 15.4 3.7 7.3 6.9 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF869 PF05911.6 EMC79813.1 - 3.1 5.9 63.1 0.58 8.3 35.0 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DZR PF12773.2 EMC79813.1 - 4.5 7.1 14.2 5.1 7.0 3.2 2.6 1 1 2 3 3 3 0 Double zinc ribbon Baculo_IE-1 PF05290.6 EMC79813.1 - 5.8 6.6 10.3 0.46 10.2 2.9 2.5 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 EMC79814.1 - 4.9e-26 90.4 0.1 7.3e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC79814.1 - 1.8e-21 75.5 0.0 1.2e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC79814.1 - 0.00072 19.3 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PhzC-PhzF PF02567.11 EMC79815.1 - 4.4e-60 203.2 0.0 5.2e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.14 EMC79815.1 - 0.064 13.1 0.0 9.1 6.2 0.0 2.5 3 0 0 3 3 3 0 Diaminopimelate epimerase HLH PF00010.21 EMC79816.1 - 3.2e-18 65.1 0.1 4.7e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DERM PF14704.1 EMC79816.1 - 0.043 13.7 0.4 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Dermatopontin DUF1295 PF06966.7 EMC79816.1 - 0.073 12.3 0.1 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) SIR2 PF02146.12 EMC79817.1 - 3.9e-62 209.1 0.0 6.7e-62 208.3 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EMC79817.1 - 0.0037 16.8 0.2 0.0064 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EMC79817.1 - 0.026 14.2 0.0 5.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DnaJ PF00226.26 EMC79818.1 - 2e-17 62.6 0.5 3.7e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain Luteo_P1-P2 PF08467.5 EMC79818.1 - 0.012 14.4 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Vinculin PF01044.14 EMC79819.1 - 1.1e-43 149.4 2.1 1.3e-43 149.3 1.5 1.0 1 0 0 1 1 1 1 Vinculin family LRR_8 PF13855.1 EMC79820.1 - 1.3e-58 194.6 59.7 1.3e-14 53.6 1.3 5.3 1 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EMC79820.1 - 5.4e-31 105.6 35.0 1.1e-06 28.0 0.3 6.6 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC79820.1 - 3e-30 104.5 0.3 9.4e-13 47.9 0.1 3.1 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC79820.1 - 1.2e-19 67.3 37.1 0.011 15.6 0.5 11.1 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 EMC79820.1 - 2.2e-12 45.6 28.6 0.076 13.1 0.7 9.7 8 1 1 9 9 9 5 Leucine Rich repeat LRR_7 PF13504.1 EMC79820.1 - 2.7e-09 35.6 40.0 0.075 13.2 0.6 10.8 11 0 0 11 11 11 3 Leucine rich repeat LRR_9 PF14580.1 EMC79820.1 - 4.9e-07 29.4 3.1 0.011 15.2 0.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.13 EMC79820.1 - 4.4e-06 26.0 0.9 4.4e-06 26.0 0.6 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_2 PF07723.8 EMC79820.1 - 0.073 13.5 6.7 12 6.6 0.1 6.5 7 1 1 8 8 8 0 Leucine Rich Repeat EphA2_TM PF14575.1 EMC79820.1 - 0.17 12.2 0.1 0.69 10.3 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cornifin PF02389.10 EMC79822.1 - 1.4 8.6 32.5 9.1 5.9 11.9 2.1 1 1 1 2 2 2 0 Cornifin (SPRR) family Synaptobrevin PF00957.16 EMC79823.1 - 4.1e-29 100.0 0.4 4.7e-29 99.8 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin CD34_antigen PF06365.7 EMC79823.1 - 0.047 13.3 0.2 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Corona_S2 PF01601.11 EMC79823.1 - 0.13 10.3 0.1 0.15 10.1 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein UCH PF00443.24 EMC79824.1 - 3.6e-18 65.6 0.0 1e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC79824.1 - 2e-05 24.6 0.4 3.9e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC79824.1 - 0.0032 16.9 0.1 0.0044 16.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SapA PF02199.10 EMC79825.1 - 1.7e-12 46.8 7.7 2.9e-12 46.1 5.3 1.3 1 0 0 1 1 1 1 Saposin A-type domain MspA PF09203.6 EMC79825.1 - 3.6 7.0 22.4 0.49 9.8 4.2 3.3 1 1 0 3 3 3 0 MspA OMP_b-brl_2 PF13568.1 EMC79825.1 - 7.2 6.3 11.5 0.77 9.5 0.4 3.6 2 2 0 3 3 3 0 Outer membrane protein beta-barrel domain CLN5 PF15014.1 EMC79826.1 - 0.42 9.9 4.9 5.8 6.1 0.3 2.2 1 1 1 2 2 2 0 Ceroid-lipofuscinosis neuronal protein 5 Toxin_23 PF08093.6 EMC79826.1 - 4.1 7.4 12.6 5.7 6.9 0.8 3.3 3 0 0 3 3 3 0 Magi 5 toxic peptide family DUF1777 PF08648.7 EMC79827.1 - 5.2e-51 172.9 33.6 5.8e-51 172.7 23.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF2217 PF10265.4 EMC79827.1 - 2.3 6.8 6.8 2.4 6.8 4.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4614 PF15391.1 EMC79827.1 - 4.9 6.8 9.0 6 6.6 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF566 PF04484.7 EMC79827.1 - 5.7 6.3 11.1 5.6 6.3 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MIP-T3 PF10243.4 EMC79827.1 - 8.7 4.6 22.9 8.8 4.6 15.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hexokinase_2 PF03727.11 EMC79828.1 - 6.7e-211 696.7 1.1 4.7e-105 350.1 0.2 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EMC79828.1 - 8e-134 443.3 1.6 2.3e-87 291.6 0.1 2.3 2 0 0 2 2 2 2 Hexokinase Rotavirus_VP3 PF06929.6 EMC79828.1 - 0.2 9.5 0.0 1.7 6.4 0.0 1.9 2 0 0 2 2 2 0 Rotavirus VP3 protein BTB PF00651.26 EMC79829.1 - 1.2e-14 54.1 0.0 1.4e-13 50.8 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EMC79829.1 - 1.1e-07 31.6 0.4 3.1e-07 30.1 0.3 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Annexin PF00191.15 EMC79830.1 - 9.3e-95 310.5 5.8 6e-24 83.7 0.0 4.0 4 0 0 4 4 4 4 Annexin BMP2K_C PF15282.1 EMC79831.1 - 4.9e-60 203.5 12.5 4.9e-60 203.5 8.6 3.2 3 2 0 3 3 3 2 BMP-2-inducible protein kinase C-terminus RFamide_26RFa PF11109.3 EMC79832.1 - 1.3e-24 86.6 3.4 1.5e-24 86.3 2.3 1.0 1 0 0 1 1 1 1 Orexigenic neuropeptide Qrfp/P518 Fibrinogen_C PF00147.13 EMC79833.1 - 7.5e-11 42.0 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Transposase_22 PF02994.9 EMC79833.1 - 0.0059 15.1 0.1 0.0079 14.7 0.1 1.1 1 0 0 1 1 1 1 L1 transposable element CENP-F_leu_zip PF10473.4 EMC79833.1 - 0.045 13.6 2.7 0.07 12.9 1.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EMC79833.1 - 0.092 12.5 0.8 5.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 EMC79833.1 - 0.1 12.8 4.5 0.19 12.0 0.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin EF-hand_1 PF00036.27 EMC79834.1 - 0.0023 17.0 3.3 0.091 12.1 0.4 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EMC79834.1 - 0.0046 17.0 0.1 0.0074 16.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC79834.1 - 0.0051 16.5 0.0 0.068 13.0 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EMC79834.1 - 0.043 13.4 0.6 0.95 9.1 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain pair PAP2 PF01569.16 EMC79836.1 - 3.2e-16 59.1 4.1 5.2e-16 58.4 2.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EMC79836.1 - 0.097 12.9 0.5 0.097 12.9 0.3 1.7 2 0 0 2 2 2 0 PAP2 superfamily C-terminal BAT2_N PF07001.6 EMC79837.1 - 2.8e-80 269.1 9.7 2.8e-80 269.1 6.7 6.7 6 3 1 7 7 7 1 BAT2 N-terminus PMT PF02366.13 EMC79838.1 - 6.8e-88 294.1 23.9 6.8e-88 294.1 16.6 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMC79838.1 - 9e-13 48.1 0.6 1.6e-12 47.4 0.4 1.3 1 0 0 1 1 1 1 MIR domain PRK PF00485.13 EMC79839.1 - 7.7e-35 120.2 0.2 9.8e-35 119.8 0.2 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Dispanin PF04505.7 EMC79840.1 - 1.2e-18 66.4 0.1 1.5e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Yip1 PF04893.12 EMC79840.1 - 0.0083 15.6 0.3 0.0092 15.4 0.2 1.0 1 0 0 1 1 1 1 Yip1 domain DUF4190 PF13828.1 EMC79840.1 - 0.023 14.2 0.2 0.023 14.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) FtsX PF02687.16 EMC79840.1 - 0.027 14.2 1.9 0.032 13.9 1.3 1.1 1 0 0 1 1 1 0 FtsX-like permease family Choline_transpo PF04515.7 EMC79840.1 - 0.13 10.9 4.6 0.19 10.4 3.2 1.3 1 1 0 1 1 1 0 Plasma-membrane choline transporter DUF4131 PF13567.1 EMC79840.1 - 0.67 9.3 3.0 0.8 9.0 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Med27 PF11571.3 EMC79841.1 - 3.5e-26 91.1 0.1 7.8e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 NaeI PF09126.5 EMC79841.1 - 0.15 10.7 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI Laminin_N PF00055.12 EMC79842.1 - 5.2e-29 100.8 0.0 1.2e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 EMC79842.1 - 2.8e-21 75.1 68.1 3e-09 36.6 9.7 4.7 3 1 1 4 4 4 3 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EMC79842.1 - 0.0058 16.7 9.8 0.0058 16.7 6.8 6.2 6 0 0 6 6 6 1 EGF-like domain EGF PF00008.22 EMC79842.1 - 0.0062 16.4 8.7 0.0062 16.4 6.0 5.1 3 1 0 3 3 3 1 EGF-like domain BNR PF02012.15 EMC79842.1 - 0.012 15.3 1.1 0.93 9.5 0.0 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat hEGF PF12661.2 EMC79842.1 - 0.049 13.7 0.6 0.049 13.7 0.4 5.9 8 0 0 8 8 8 0 Human growth factor-like EGF AAA_11 PF13086.1 EMC79843.1 - 3e-62 210.2 1.9 3e-62 210.2 1.3 3.7 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EMC79843.1 - 7.5e-54 182.1 0.1 2e-53 180.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC79843.1 - 8.8e-10 38.1 0.0 5.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMC79843.1 - 1.6e-08 34.3 0.7 0.0081 15.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EMC79843.1 - 2e-07 30.7 0.6 0.097 12.1 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EMC79843.1 - 5.4e-05 23.3 0.2 0.00039 20.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC79843.1 - 6.5e-05 22.9 0.0 0.00021 21.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 EMC79843.1 - 0.065 13.3 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain IncA PF04156.9 EMC79843.1 - 2.3 7.7 11.8 0.51 9.8 4.6 2.6 2 0 0 2 2 2 0 IncA protein Myb_DNA-bind_6 PF13921.1 EMC79844.1 - 3.3e-18 65.5 5.7 7.3e-15 54.8 0.1 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMC79844.1 - 1.2e-11 44.4 7.4 7.4e-07 29.1 0.0 3.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain Poxvirus_B22R_N PF13169.1 EMC79844.1 - 0.018 15.2 0.7 0.098 12.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal DUF217 PF02697.9 EMC79844.1 - 0.058 13.6 4.4 15 5.9 0.0 3.9 3 1 1 4 4 4 0 Uncharacterized ACR, COG1753 CarD_CdnL_TRCF PF02559.11 EMC79844.1 - 0.17 11.9 1.4 2.1 8.4 0.2 2.8 1 1 2 3 3 3 0 CarD-like/TRCF domain DUF956 PF06115.6 EMC79844.1 - 0.47 10.0 4.5 3.5 7.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF956) Myb_DNA-bind_4 PF13837.1 EMC79844.1 - 0.97 9.6 10.8 8.8 6.5 3.7 3.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Phage_pRha PF09669.5 EMC79844.1 - 1.9 8.9 6.0 7.5 6.9 0.0 3.3 2 2 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) DUF4483 PF14825.1 EMC79845.1 - 8.9e-49 165.9 0.0 9.8e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Homeobox PF00046.24 EMC79846.1 - 6.2e-23 80.1 5.7 9.9e-23 79.5 4.0 1.3 1 0 0 1 1 1 1 Homeobox domain SAGA-Tad1 PF12767.2 EMC79846.1 - 7.4e-05 22.5 0.2 8.5e-05 22.3 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Homez PF11569.3 EMC79846.1 - 0.085 11.9 1.2 0.18 10.8 0.8 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DEAD PF00270.24 EMC79847.1 - 4.7e-41 140.0 0.0 1.2e-40 138.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC79847.1 - 1.5e-24 85.6 0.0 5.9e-24 83.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMC79847.1 - 6.3e-17 60.8 0.1 1.2e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EMC79847.1 - 0.0024 17.7 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EMC79847.1 - 0.012 15.5 0.1 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain SecA_DEAD PF07517.9 EMC79847.1 - 0.014 14.7 0.1 0.11 11.7 0.0 2.1 2 1 0 2 2 2 0 SecA DEAD-like domain FF PF01846.14 EMC79847.1 - 0.03 14.2 0.2 0.71 9.8 0.0 2.5 2 0 0 2 2 2 0 FF domain zf-TFIIIC PF12660.2 EMC79848.1 - 9.2e-23 80.0 1.6 2.6e-22 78.5 1.1 1.8 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 EMC79848.1 - 2.2e-14 53.5 0.0 5e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term ADK PF00406.17 EMC79849.1 - 0.0064 16.3 0.1 0.0067 16.3 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMC79849.1 - 0.0096 15.5 0.1 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid DUF4375 PF14300.1 EMC79849.1 - 0.075 13.0 0.8 0.1 12.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) ADK PF00406.17 EMC79850.1 - 8e-42 142.6 0.0 3.1e-24 85.5 0.0 2.4 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 EMC79850.1 - 3.8e-17 63.2 0.0 3.9e-09 37.3 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMC79850.1 - 4.4e-13 49.3 0.0 4.6e-08 33.0 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.1 EMC79850.1 - 9e-13 48.6 0.0 3.9e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EMC79850.1 - 7.2e-08 32.7 0.0 0.0019 18.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 EMC79850.1 - 6.6e-06 25.5 0.0 0.049 12.8 0.0 2.4 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_16 PF13191.1 EMC79850.1 - 1.7e-05 24.9 0.0 0.0093 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC79850.1 - 3e-05 24.1 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMC79850.1 - 0.00012 21.7 0.0 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain ABC_tran PF00005.22 EMC79850.1 - 0.0011 19.2 0.0 0.47 10.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 EMC79850.1 - 0.0012 18.9 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EMC79850.1 - 0.0037 16.6 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMC79850.1 - 0.0042 17.0 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EMC79850.1 - 0.0061 16.6 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EMC79850.1 - 0.0068 16.1 0.1 4.4 7.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SKI PF01202.17 EMC79850.1 - 0.007 16.2 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Mg_chelatase PF01078.16 EMC79850.1 - 0.0079 15.3 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMC79850.1 - 0.0085 15.1 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RIIa PF02197.12 EMC79850.1 - 0.0099 15.2 0.0 0.032 13.6 0.0 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Thymidylate_kin PF02223.12 EMC79850.1 - 0.011 15.1 0.0 8 5.7 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase NACHT PF05729.7 EMC79850.1 - 0.016 14.9 0.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain PMBR PF09373.5 EMC79850.1 - 0.02 14.8 0.0 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat MobB PF03205.9 EMC79850.1 - 0.036 13.7 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EMC79850.1 - 0.05 13.5 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dpy-30 PF05186.8 EMC79850.1 - 0.067 12.6 0.1 0.2 11.1 0.0 1.9 2 0 0 2 2 1 0 Dpy-30 motif ATP_bind_1 PF03029.12 EMC79850.1 - 0.079 12.4 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EMC79850.1 - 0.082 12.3 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EMC79850.1 - 0.12 11.8 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EMC79850.1 - 0.13 11.3 0.0 5 6.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 EMC79850.1 - 0.13 11.7 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain APS_kinase PF01583.15 EMC79850.1 - 0.14 11.7 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF4561 PF15120.1 EMC79851.1 - 3.5e-82 273.9 3.7 3.8e-82 273.8 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4561) Allexi_40kDa PF05549.6 EMC79851.1 - 0.02 14.1 0.6 0.025 13.8 0.1 1.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein zf-H2C2_2 PF13465.1 EMC79852.1 - 2.8e-28 96.7 42.6 7.1e-08 32.3 1.3 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC79852.1 - 5.6e-27 92.4 51.8 2.4e-05 24.4 1.6 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC79852.1 - 2.6e-22 77.4 38.1 0.0017 18.5 0.3 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC79852.1 - 1.3e-14 53.8 29.0 0.0077 16.3 0.0 7.0 7 0 0 7 7 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC79852.1 - 1.8e-07 31.1 38.9 0.0092 16.1 0.2 6.7 7 0 0 7 7 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC79852.1 - 2.7e-07 30.2 32.0 0.00019 21.1 1.0 6.5 5 1 1 6 6 6 2 C2H2-type zinc finger C1_1 PF00130.17 EMC79852.1 - 4.2e-06 26.3 17.3 0.16 11.7 2.8 3.7 2 1 1 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.4 EMC79852.1 - 0.00012 21.8 10.3 0.077 12.8 0.1 4.1 3 1 0 3 3 3 2 Zinc-finger domain Prok-RING_1 PF14446.1 EMC79852.1 - 0.00062 19.4 14.5 6.6 6.5 0.0 6.0 6 0 0 6 6 6 1 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.5 EMC79852.1 - 0.0011 18.8 23.3 0.066 13.1 1.1 5.2 4 2 0 4 4 4 1 Zinc ribbon domain Ta0938 PF11494.3 EMC79852.1 - 0.0087 16.1 0.2 3.2 7.9 0.0 2.5 2 0 0 2 2 2 1 Ta0938 zf-BED PF02892.10 EMC79852.1 - 0.036 13.8 2.3 0.036 13.8 1.6 5.8 4 2 2 6 6 6 0 BED zinc finger Rpr2 PF04032.11 EMC79852.1 - 0.075 12.9 0.1 0.075 12.9 0.1 3.3 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.16 EMC79852.1 - 0.11 12.4 29.1 3.3 7.6 6.0 4.2 1 1 2 3 3 3 0 FYVE zinc finger GAGA PF09237.6 EMC79852.1 - 0.13 11.8 7.0 5.7 6.6 0.1 3.6 2 2 2 4 4 4 0 GAGA factor PyrI_C PF02748.10 EMC79852.1 - 0.71 9.3 15.4 2.4 7.6 0.1 5.2 3 1 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 EMC79852.1 - 1.7 8.7 29.6 2.1 8.4 0.5 5.9 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) BolA PF01722.13 EMC79852.1 - 1.8 8.5 5.4 15 5.6 0.1 3.3 2 1 1 3 3 3 0 BolA-like protein Ribosomal_S27e PF01667.12 EMC79852.1 - 4.9 6.7 13.3 1.3 8.6 0.1 4.7 3 1 2 5 5 5 0 Ribosomal protein S27 Elf1 PF05129.8 EMC79852.1 - 5.8 6.6 21.4 0.21 11.2 1.4 3.8 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like DUF2321 PF10083.4 EMC79852.1 - 6.6 6.2 10.9 49 3.3 1.5 3.7 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) COesterase PF00135.23 EMC79853.1 - 1.2e-156 522.6 0.0 1.3e-156 522.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC79853.1 - 7.8e-07 28.8 0.0 2.2e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC79853.1 - 0.00026 20.2 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EMC79854.1 - 3.3e-26 92.1 0.2 3.6e-26 91.9 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family TraO PF10626.4 EMC79854.1 - 0.043 13.1 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TraO Tau95 PF09734.4 EMC79855.1 - 3.3e-61 207.3 0.6 4.9e-61 206.7 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit RasGEF PF00617.14 EMC79857.1 - 3e-60 203.2 0.2 4.5e-60 202.6 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RA PF00788.18 EMC79857.1 - 2.8e-14 53.3 0.0 9.5e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Acyl-CoA_ox_N PF14749.1 EMC79857.1 - 6.2e-05 23.2 0.5 0.66 10.2 0.0 2.8 2 0 0 2 2 2 2 Acyl-coenzyme A oxidase N-terminal Glyco_transf_6 PF03414.8 EMC79858.1 - 2.3e-145 483.3 0.0 2.7e-145 483.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_tranf_2_4 PF13704.1 EMC79858.1 - 0.04 14.2 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 SURF6 PF04935.7 EMC79859.1 - 1.2e-47 162.0 67.8 1.2e-47 162.0 47.0 2.1 1 1 1 2 2 2 1 Surfeit locus protein 6 Med22 PF06179.7 EMC79860.1 - 6.3e-35 119.5 4.7 8e-35 119.1 3.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UPRTase PF14681.1 EMC79860.1 - 0.036 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase SURF1 PF02104.10 EMC79861.1 - 7.5e-57 192.5 0.0 9e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family SURF2 PF05477.6 EMC79862.1 - 1.6e-95 318.8 11.6 1.9e-95 318.6 8.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) SURF4 PF02077.10 EMC79863.1 - 6.5e-128 425.7 7.6 7.3e-128 425.5 5.3 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 EMC79863.1 - 0.02 15.2 0.1 0.02 15.2 0.1 3.4 4 1 1 5 5 5 0 DoxX Pkinase PF00069.20 EMC79864.1 - 2.2e-35 122.0 0.8 2.4e-35 121.9 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79864.1 - 3.4e-27 95.1 1.7 3.7e-27 95.0 1.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC79864.1 - 3.4e-05 22.9 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC79864.1 - 0.0045 16.0 0.1 0.0061 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_T PF00929.19 EMC79866.1 - 7.1e-28 97.9 0.0 1.4e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EMC79866.1 - 7.2e-05 22.3 0.0 0.00019 20.9 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease DUF243 PF03103.12 EMC79866.1 - 0.11 12.6 6.3 0.62 10.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF243) Cg6151-P PF10233.4 EMC79867.1 - 1.4e-35 121.6 3.1 1.7e-35 121.4 2.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4191 PF13829.1 EMC79867.1 - 0.073 12.1 1.5 0.093 11.8 0.0 1.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4191) DUF3522 PF12036.3 EMC79868.1 - 9.1e-60 201.6 6.0 1.1e-59 201.3 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Oxidored_q5_N PF01059.12 EMC79868.1 - 0.08 12.8 4.9 0.21 11.4 2.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus FAM163 PF15069.1 EMC79869.1 - 1.1e-53 181.6 0.1 1.3e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 FAM163 family Herpes_LMP2 PF07415.6 EMC79869.1 - 0.0066 15.0 3.5 0.03 12.9 0.3 2.0 2 0 0 2 2 2 2 Gammaherpesvirus latent membrane protein (LMP2) protein DUF4006 PF13179.1 EMC79869.1 - 0.011 15.2 2.7 0.019 14.4 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) EphA2_TM PF14575.1 EMC79869.1 - 0.095 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HCV_NS4a PF01006.15 EMC79869.1 - 1.4 8.4 4.5 2.9 7.5 2.2 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Bromodomain PF00439.20 EMC79871.1 - 2e-42 142.9 4.1 2.5e-24 84.9 0.3 2.5 2 0 0 2 2 2 2 Bromodomain Gon7 PF08738.5 EMC79871.1 - 0.0022 17.9 5.9 0.0022 17.9 4.1 3.4 4 1 1 5 5 5 1 Gon7 family Pol_alpha_B_N PF08418.5 EMC79871.1 - 0.004 16.7 14.2 0.004 16.7 9.8 4.2 3 2 2 5 5 5 1 DNA polymerase alpha subunit B N-terminal MerR-DNA-bind PF09278.6 EMC79871.1 - 1.9 8.9 5.2 32 5.0 0.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding WD40 PF00400.27 EMC79872.1 - 1.1e-77 253.4 21.1 9.9e-13 47.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMC79872.1 - 2.1e-13 49.3 6.8 0.00058 18.1 0.5 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EMC79872.1 - 4e-12 46.2 1.1 8.1e-06 25.6 0.0 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 EMC79872.1 - 0.00078 18.7 1.8 9.5 5.3 0.0 4.4 2 1 2 5 5 5 2 TUP1-like enhancer of split Nucleoporin_N PF08801.6 EMC79872.1 - 0.0029 16.4 8.1 0.049 12.3 1.1 4.2 1 1 1 3 3 3 1 Nup133 N terminal like DUF3312 PF11768.3 EMC79872.1 - 0.007 14.6 0.0 0.099 10.8 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3312) CDtoxinA PF03498.9 EMC79872.1 - 0.032 13.5 1.2 0.21 10.9 0.1 2.5 1 1 0 2 2 2 0 Cytolethal distending toxin A/C family VID27 PF08553.5 EMC79872.1 - 0.074 11.2 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Hormone_recep PF00104.25 EMC79874.1 - 4.1e-42 143.6 0.0 5.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.3 EMC79874.1 - 3e-38 130.1 25.5 4.9e-38 129.4 17.7 1.4 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.13 EMC79874.1 - 3.7e-32 110.3 16.2 6.2e-32 109.6 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Collagen PF01391.13 EMC79876.1 - 5.9e-171 554.1 703.7 9.3e-09 34.7 14.9 22.5 3 1 13 16 16 16 11 Collagen triple helix repeat (20 copies) COLFI PF01410.13 EMC79876.1 - 4.6e-85 284.3 0.1 6.7e-85 283.8 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 EMC79876.1 - 2.3e-11 43.8 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 EMC79876.1 - 2.3e-05 24.6 0.0 4.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 EMC79876.1 - 0.048 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF781 PF05612.7 EMC79876.1 - 2.3 6.8 0.1 3.4 6.2 0.0 1.1 1 0 0 1 1 1 0 Mouse protein of unknown function (DUF781) OLF PF02191.11 EMC79877.1 - 2.7e-98 328.2 6.4 4.5e-98 327.4 4.4 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 EMC79877.1 - 3.4e-50 168.0 9.0 9.4e-50 166.5 3.5 2.7 3 0 0 3 3 3 1 Neurogenesis glycoprotein Nup54 PF13874.1 EMC79877.1 - 0.0024 17.5 8.6 0.0024 17.5 6.0 1.6 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 IncA PF04156.9 EMC79877.1 - 0.0031 17.1 13.5 0.0056 16.2 9.3 1.4 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 EMC79877.1 - 0.0045 15.9 9.6 0.0069 15.3 6.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Pox_A_type_inc PF04508.7 EMC79877.1 - 0.0081 15.8 0.6 0.032 13.9 0.4 2.0 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.7 EMC79877.1 - 0.011 15.5 2.2 0.14 11.9 1.5 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lipoprotein_7 PF01540.11 EMC79877.1 - 0.017 14.2 2.7 0.025 13.6 1.9 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Reo_sigmaC PF04582.7 EMC79877.1 - 0.033 13.3 0.2 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3926 PF13080.1 EMC79877.1 - 0.066 12.7 0.6 0.14 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) NPV_P10 PF05531.7 EMC79877.1 - 0.066 13.4 3.5 4.9 7.4 2.4 3.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FH2 PF02181.18 EMC79877.1 - 0.11 11.3 8.8 0.41 9.4 0.1 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain Prismane PF03063.15 EMC79877.1 - 0.15 10.4 0.8 0.2 9.9 0.6 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF1664 PF07889.7 EMC79877.1 - 0.15 11.8 8.6 2.7 7.8 2.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Xpo1 PF08389.7 EMC79877.1 - 0.15 11.9 2.0 0.15 11.9 0.3 1.7 1 1 0 2 2 2 0 Exportin 1-like protein V_ATPase_I PF01496.14 EMC79877.1 - 0.23 9.2 6.4 0.36 8.6 4.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.20 EMC79877.1 - 0.23 11.6 10.3 0.19 11.8 3.2 2.8 1 1 1 2 2 2 0 Syntaxin Borrelia_REV PF03978.8 EMC79877.1 - 0.8 9.4 5.3 12 5.5 0.1 2.3 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein DUF310 PF03750.8 EMC79877.1 - 1.3 9.2 7.3 36 4.5 5.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF310) Laminin_II PF06009.7 EMC79877.1 - 1.3 8.7 8.4 0.61 9.8 2.3 2.4 1 1 1 2 2 2 0 Laminin Domain II H-kinase_dim PF02895.9 EMC79877.1 - 1.5 9.2 7.7 47 4.4 5.3 2.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF2203 PF09969.4 EMC79877.1 - 1.6 8.9 9.7 1.6 8.9 0.4 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) MitMem_reg PF13012.1 EMC79877.1 - 1.7 8.7 9.6 1.3 9.1 4.3 2.5 2 1 0 2 2 1 0 Maintenance of mitochondrial structure and function DUF848 PF05852.6 EMC79877.1 - 1.9 8.3 12.2 5.9 6.7 3.2 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Cytochrom_B562 PF07361.6 EMC79877.1 - 2.2 8.7 9.5 3 8.3 4.1 2.2 1 1 1 2 2 2 0 Cytochrome b562 DUF1978 PF09321.5 EMC79877.1 - 2.2 7.6 12.8 0.45 9.9 1.9 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1978) Fib_alpha PF08702.5 EMC79877.1 - 2.8 8.0 11.0 5.5 7.0 5.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 EMC79877.1 - 5.3 7.0 16.6 1.8e+02 2.0 11.5 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin_2 PF14523.1 EMC79877.1 - 5.6 7.0 11.7 65 3.6 6.7 2.5 1 1 1 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.4 EMC79877.1 - 5.8 7.1 13.8 1.6 8.9 1.2 3.4 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.16 EMC79877.1 - 6.7 7.0 12.5 12 6.2 0.4 2.5 1 1 1 2 2 2 0 Spectrin repeat ADIP PF11559.3 EMC79877.1 - 7 6.5 15.3 5.5 6.8 6.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 EMC79877.1 - 8 4.7 11.6 1.8 6.8 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WHEP-TRS PF00458.15 EMC79878.1 - 0.034 13.8 5.2 0.46 10.1 1.7 3.4 3 0 0 3 3 3 0 WHEP-TRS domain Acyltransferase PF01553.16 EMC79879.1 - 2.6e-35 120.7 0.0 3.3e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase DUF1107 PF06526.7 EMC79879.1 - 0.062 13.1 0.3 12 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) Exo_endo_phos PF03372.18 EMC79881.1 - 5.4e-20 72.3 0.3 7.6e-20 71.8 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.16 EMC79882.1 - 1.2e-41 142.3 0.0 2.4e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMC79882.1 - 3e-40 137.4 0.0 7.3e-40 136.1 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2695 PF10905.3 EMC79882.1 - 0.044 13.5 0.1 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) ERM PF00769.14 EMC79883.1 - 2.8e-05 23.7 16.4 3.5e-05 23.4 11.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF724 PF05266.9 EMC79883.1 - 0.016 14.8 15.6 0.024 14.2 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3781 PF12636.2 EMC79883.1 - 0.061 13.2 0.4 0.14 12.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Tropomyosin PF00261.15 EMC79883.1 - 0.077 12.0 20.5 0.46 9.5 14.2 2.0 1 1 0 1 1 1 0 Tropomyosin LNP1 PF15419.1 EMC79883.1 - 0.15 12.1 6.4 0.28 11.2 4.5 1.5 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 V_ATPase_I PF01496.14 EMC79883.1 - 0.18 9.5 11.9 0.19 9.5 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2514 PF10721.4 EMC79883.1 - 0.59 9.8 12.5 2 8.0 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) GAS PF13851.1 EMC79883.1 - 0.83 8.8 24.3 0.4 9.8 5.9 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PAP_central PF04928.12 EMC79883.1 - 1.1 8.0 5.7 1.2 7.8 4.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain NYD-SP28_assoc PF14775.1 EMC79883.1 - 6.2 6.5 12.2 1.9 8.2 2.9 3.4 3 1 0 3 3 3 0 Sperm tail C-terminal domain Fib_alpha PF08702.5 EMC79883.1 - 8.4 6.5 17.3 7.1 6.7 0.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 EMC79883.1 - 8.6 6.7 21.5 1.7 9.0 6.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) zf-DNL PF05180.7 EMC79885.1 - 4.6e-27 93.5 0.1 5.6e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 DNL zinc finger TPR_12 PF13424.1 EMC79886.1 - 1.2e-51 172.5 55.1 2.1e-09 37.1 0.6 6.1 3 2 6 9 9 8 8 Tetratricopeptide repeat GoLoco PF02188.12 EMC79886.1 - 4.3e-42 140.5 23.9 9.4e-11 40.7 0.3 4.6 4 0 0 4 4 4 4 GoLoco motif TPR_1 PF00515.23 EMC79886.1 - 8e-36 120.1 29.1 1.5e-05 24.3 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 EMC79886.1 - 3.8e-29 98.1 18.1 1.4e-05 24.5 0.2 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 EMC79886.1 - 2.5e-21 75.0 25.1 1.2e-06 28.0 0.8 6.2 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 EMC79886.1 - 9.8e-21 71.9 31.2 0.0015 18.2 0.1 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EMC79886.1 - 5.6e-16 57.0 24.2 0.0014 18.3 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 EMC79886.1 - 1.8e-15 56.2 16.2 0.072 13.0 0.0 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC79886.1 - 1.1e-08 34.9 6.5 13 6.7 0.0 7.7 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC79886.1 - 1.6e-06 28.6 16.3 0.053 14.2 0.2 6.2 3 2 5 8 8 7 5 Tetratricopeptide repeat Rapsyn_N PF10579.4 EMC79886.1 - 2.3e-05 24.1 1.5 1.1 9.0 0.0 4.7 3 3 2 5 5 5 2 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.9 EMC79886.1 - 4.3e-05 23.5 4.9 14 6.4 0.0 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC79886.1 - 0.00024 21.0 16.5 3 8.2 0.0 7.2 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC79886.1 - 0.001 19.1 15.7 0.49 10.5 1.9 5.1 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 UreE_C PF05194.7 EMC79886.1 - 0.0043 17.1 1.4 1.5 8.9 0.1 3.6 3 1 1 4 4 4 1 UreE urease accessory protein, C-terminal domain FliJ PF02050.11 EMC79886.1 - 0.24 11.4 5.4 1.2 9.1 0.2 3.7 2 2 3 5 5 5 0 Flagellar FliJ protein TPR_6 PF13174.1 EMC79886.1 - 0.32 11.5 12.5 1.5e+02 3.2 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat PcfJ PF14284.1 EMC79887.1 - 0.19 11.2 3.4 0.27 10.7 2.4 1.2 1 0 0 1 1 1 0 PcfJ-like protein KxDL PF10241.4 EMC79887.1 - 0.34 10.8 6.4 0.24 11.3 3.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein Evr1_Alr PF04777.8 EMC79888.1 - 1e-26 92.6 0.3 2.6e-26 91.3 0.2 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.15 EMC79888.1 - 0.00059 19.4 0.0 0.0085 15.7 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin Sep15_SelM PF08806.6 EMC79888.1 - 0.00074 19.2 0.1 0.0032 17.1 0.0 2.1 2 0 0 2 2 2 1 Sep15/SelM redox domain Homeobox PF00046.24 EMC79889.1 - 3.4e-21 74.5 2.1 6.2e-21 73.7 1.5 1.4 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 EMC79889.1 - 5.5e-16 58.3 11.7 7.3e-14 51.5 8.1 2.3 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.6 EMC79889.1 - 0.0002 21.0 0.0 0.00047 19.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Orbi_VP3 PF01700.11 EMC79889.1 - 0.19 9.0 0.0 0.28 8.5 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Axin_b-cat_bind PF08833.5 EMC79891.1 - 0.2 11.3 6.3 1.2 8.8 0.2 3.5 5 0 0 5 5 5 0 Axin beta-catenin binding domain RunxI PF08504.6 EMC79891.1 - 2.8 8.4 7.3 3.8 8.0 0.1 2.9 1 1 0 2 2 2 0 Runx inhibition domain CAMSAP_CKK PF08683.6 EMC79893.1 - 3.8e-51 171.9 0.1 8.4e-51 170.8 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH PF00307.26 EMC79893.1 - 4.7e-33 113.4 0.3 1.5e-32 111.8 0.2 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC79893.1 - 5.5e-32 109.2 0.2 1.3e-31 108.1 0.2 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Galactosyl_T PF01762.16 EMC79894.1 - 9.2e-40 136.3 0.0 1.2e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC79894.1 - 9.1e-08 31.6 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Proteasom_PSMB PF10508.4 EMC79895.1 - 3.3e-165 550.1 0.0 3.7e-165 550.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 EMC79895.1 - 0.00023 21.3 0.1 0.22 11.8 0.1 3.6 2 2 1 3 3 3 1 HEAT repeats RICTOR_V PF14668.1 EMC79895.1 - 0.0011 18.8 0.1 15 5.5 0.0 3.6 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 RTTN_N PF14726.1 EMC79895.1 - 0.042 14.4 0.0 16 6.1 0.0 3.1 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning DUF3554 PF12074.3 EMC79895.1 - 0.06 12.7 0.3 3.5 6.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3554) Neurochondrin PF05536.6 EMC79895.1 - 0.084 11.1 0.2 1.1 7.4 0.0 2.3 1 1 1 2 2 2 0 Neurochondrin CutA1 PF03091.10 EMC79896.1 - 2.6e-29 100.8 0.0 3.1e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein PHD PF00628.24 EMC79897.1 - 4.3e-14 51.9 19.5 1.4e-08 34.2 1.7 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 EMC79897.1 - 6.9e-05 22.0 3.7 6.9e-05 22.0 2.5 3.8 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 EMC79897.1 - 0.00069 19.2 0.3 0.00069 19.2 0.2 3.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 DUF4537 PF15057.1 EMC79897.1 - 0.0032 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) C1_1 PF00130.17 EMC79897.1 - 0.03 14.0 0.7 0.03 14.0 0.5 4.0 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2M_comp PF07678.9 EMC79898.1 - 5.5e-67 225.5 0.2 8.6e-67 224.9 0.1 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 EMC79898.1 - 6.2e-28 96.2 1.2 8.1e-27 92.6 0.0 2.8 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 EMC79898.1 - 3e-24 85.3 0.1 3.5e-23 81.9 0.0 2.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region NTR PF01759.16 EMC79898.1 - 1.7e-22 79.1 0.7 4.6e-22 77.6 0.1 2.1 2 0 0 2 2 2 1 UNC-6/NTR/C345C module A2M_recep PF07677.9 EMC79898.1 - 9.8e-22 76.9 0.0 3.1e-21 75.3 0.0 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.14 EMC79898.1 - 4.4e-16 58.9 0.2 1.8e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 MG2 domain ANATO PF01821.13 EMC79898.1 - 2.7e-08 33.8 7.4 8e-08 32.2 5.1 1.9 1 0 0 1 1 1 1 Anaphylotoxin-like domain Prenyltrans_2 PF13249.1 EMC79898.1 - 1.1e-07 32.2 0.4 0.00035 20.9 0.0 2.6 1 1 0 2 2 2 2 Prenyltransferase-like Prenyltrans PF00432.16 EMC79898.1 - 0.0038 16.7 0.1 0.58 9.7 0.0 2.9 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat LRR_4 PF12799.2 EMC79899.1 - 7.6e-17 60.5 34.0 1.2e-08 34.3 1.0 7.0 4 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79899.1 - 6.9e-16 57.7 31.9 1e-09 37.9 5.7 4.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 EMC79899.1 - 3.7e-15 55.9 3.5 2.3e-14 53.3 2.4 2.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EMC79899.1 - 1.2e-08 33.8 14.9 0.25 11.5 0.2 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 EMC79899.1 - 0.0001 21.9 13.2 0.052 13.6 0.4 5.6 4 1 1 5 5 5 2 Leucine Rich repeat SlyX PF04102.7 EMC79899.1 - 0.0024 18.1 6.1 0.0024 18.1 4.2 24.5 13 7 15 29 29 29 1 SlyX LRR_7 PF13504.1 EMC79899.1 - 0.014 15.4 17.4 2.8 8.5 0.0 7.2 8 0 0 8 8 8 0 Leucine rich repeat Ras PF00071.17 EMC79900.1 - 6.4e-61 204.4 0.1 7.4e-61 204.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC79900.1 - 2.1e-19 70.1 0.0 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC79900.1 - 1.3e-12 47.2 0.0 1.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC79900.1 - 4.9e-06 26.1 0.0 0.00011 21.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC79900.1 - 6.3e-06 26.1 0.0 8.1e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC79900.1 - 0.00014 21.0 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMC79900.1 - 0.0028 17.2 0.0 0.089 12.3 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMC79900.1 - 0.023 14.8 0.1 0.053 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC79900.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EMC79900.1 - 0.044 12.9 0.0 0.095 11.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 EMC79900.1 - 0.068 13.3 0.0 0.37 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 EMC79900.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1863 PF08937.6 EMC79900.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Gelsolin PF00626.17 EMC79901.1 - 2.1e-108 354.1 0.1 4.8e-21 74.2 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat CutA1 PF03091.10 EMC79901.1 - 0.21 11.2 0.3 3.9 7.1 0.0 2.9 3 0 0 3 3 3 0 CutA1 divalent ion tolerance protein Band_7 PF01145.20 EMC79902.1 - 4.2e-37 127.7 0.9 5.1e-37 127.5 0.6 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMC79902.1 - 0.00097 18.7 0.3 0.0015 18.1 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF940 PF06082.6 EMC79902.1 - 0.34 9.3 2.3 0.4 9.1 1.6 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) 7tm_4 PF13853.1 EMC79904.1 - 6.4e-62 207.6 10.4 6.4e-62 207.6 7.2 2.1 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC79904.1 - 8e-36 123.4 14.9 1.1e-35 122.9 10.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC79905.1 - 3.6e-59 198.7 10.1 3.6e-59 198.7 7.0 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC79905.1 - 4.4e-30 104.6 18.6 5.9e-30 104.2 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC79906.1 - 3.3e-59 198.7 12.7 5.4e-59 198.1 8.8 1.3 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC79906.1 - 2.7e-17 62.7 11.5 8.1e-09 34.9 0.1 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) p450 PF00067.17 EMC79907.1 - 4.2e-12 45.3 0.4 4.3e-12 45.2 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.19 EMC79908.1 - 4.2e-14 52.6 10.0 4.2e-14 52.6 6.9 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Fun_ATP-synt_8 PF05933.8 EMC79908.1 - 0.045 13.7 0.9 0.16 12.0 0.6 1.9 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) wnt PF00110.14 EMC79909.1 - 3.7e-108 361.3 20.1 4.5e-108 361.1 13.9 1.0 1 0 0 1 1 1 1 wnt family NDUF_B8 PF05821.6 EMC79910.1 - 3.2e-72 241.9 9.8 3.5e-72 241.7 6.8 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cupin_8 PF13621.1 EMC79911.1 - 1.1e-42 146.3 0.4 1.6e-42 145.7 0.3 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMC79911.1 - 1.7e-07 30.7 0.1 3.2e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EMC79911.1 - 0.041 14.1 0.2 0.22 11.7 0.1 2.2 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 EMC79911.1 - 0.06 12.8 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Cupin domain Pax2_C PF12403.3 EMC79913.1 - 3.6e-41 139.4 21.3 3.8e-41 139.3 12.5 2.7 2 1 0 2 2 2 1 Paired-box protein 2 C terminal PAX PF00292.13 EMC79913.1 - 4.7e-31 107.1 0.1 9e-31 106.1 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 EMC79913.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox PF00046.24 EMC79913.1 - 0.0075 15.8 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_IS1 PF12759.2 EMC79913.1 - 0.047 13.1 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 InsA C-terminal domain Ribosomal_S13_N PF08069.7 EMC79913.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain CUE PF02845.11 EMC79914.1 - 0.0014 18.0 0.1 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain ANTH PF07651.11 EMC79914.1 - 0.022 13.4 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 ANTH domain UCH PF00443.24 EMC79914.1 - 0.071 12.2 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EMC79914.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF2992 PF11208.3 EMC79914.1 - 0.082 12.8 2.8 0.14 12.0 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) F-box PF00646.28 EMC79915.1 - 9.5e-06 25.1 0.7 9.5e-06 25.1 0.5 3.2 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 EMC79915.1 - 1.9e-05 24.3 6.1 0.075 12.8 0.0 5.0 3 1 3 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 EMC79915.1 - 3.4e-05 23.4 3.8 11 6.4 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.2 EMC79915.1 - 0.0001 21.8 4.3 1.1 8.9 0.0 4.9 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMC79915.1 - 0.0085 16.1 10.9 1.3 9.5 0.1 6.7 7 0 0 7 7 7 1 Leucine rich repeat F-box-like PF12937.2 EMC79915.1 - 0.01 15.5 0.2 0.01 15.5 0.1 2.6 2 1 0 2 2 2 0 F-box-like LRR_1 PF00560.28 EMC79915.1 - 0.064 13.3 10.2 3.9 7.8 0.2 6.2 6 2 1 7 7 7 0 Leucine Rich Repeat PH_9 PF15410.1 EMC79916.1 - 2.7e-37 127.5 0.0 9.1e-37 125.8 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.15 EMC79916.1 - 3.4e-35 121.4 0.0 1.1e-34 119.8 0.0 1.8 1 1 0 1 1 1 1 Sec7 domain PH PF00169.24 EMC79916.1 - 2.8e-10 40.3 0.0 6.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 PH domain RHD PF00554.17 EMC79917.1 - 9.3e-67 223.9 0.1 1.5e-66 223.3 0.1 1.3 1 0 0 1 1 1 1 Rel homology domain (RHD) Ank PF00023.25 EMC79917.1 - 9e-40 132.5 14.1 6.8e-07 28.7 0.2 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 EMC79917.1 - 2e-38 130.6 6.6 1.2e-19 70.3 0.6 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMC79917.1 - 4.3e-30 100.7 4.5 4.3e-05 23.3 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EMC79917.1 - 7.9e-30 102.6 3.1 2.8e-10 40.4 0.1 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC79917.1 - 3e-26 90.8 6.4 2.1e-08 34.1 0.1 5.1 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Death PF00531.17 EMC79917.1 - 5.8e-07 29.1 0.1 3.3e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Death domain Tim44 PF04280.10 EMC79917.1 - 0.012 15.5 0.3 0.027 14.4 0.2 1.5 1 0 0 1 1 1 0 Tim44-like domain Frag1 PF10277.4 EMC79918.1 - 9.5e-44 149.4 8.2 1.1e-43 149.1 5.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2768 PF10966.3 EMC79918.1 - 0.24 11.5 3.5 0.3 11.2 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2768) UPF0506 PF11703.3 EMC79918.1 - 5.9 6.9 7.2 0.89 9.5 0.5 2.2 1 1 1 2 2 2 0 UPF0506 Homeobox PF00046.24 EMC79919.1 - 1e-22 79.4 9.2 1.7e-22 78.7 6.4 1.3 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 EMC79919.1 - 5.1e-09 35.3 1.4 5.1e-09 35.3 0.9 2.3 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.6 EMC79919.1 - 0.0042 16.7 0.7 0.012 15.2 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain UDPGT PF00201.13 EMC79920.1 - 5.4e-107 358.4 0.0 6.2e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EMC79920.1 - 0.00093 18.4 0.0 0.1 11.7 0.0 2.4 2 1 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EMC79920.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DBB PF14545.1 EMC79921.1 - 3e-46 156.4 0.1 4.8e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, EMP70 PF02990.11 EMC79922.1 - 2.9e-171 570.4 20.3 3.6e-171 570.1 14.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_8 PF00895.15 EMC79922.1 - 0.22 11.7 7.5 3.2 8.0 0.0 3.7 3 0 0 3 3 3 0 ATP synthase protein 8 Zona_pellucida PF00100.18 EMC79923.1 - 2.3e-57 194.4 2.0 3e-57 194.0 1.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.13 EMC79923.1 - 1.2e-10 40.8 4.6 2.5e-10 39.8 3.2 1.6 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF4657 PF15552.1 EMC79924.1 - 8.5e-06 25.2 4.7 8.5e-06 25.2 3.2 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4657) HAP1_N PF04849.8 EMC79924.1 - 0.0022 16.9 1.1 0.004 16.1 0.7 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region PDZ PF00595.19 EMC79925.1 - 5.6e-12 45.6 0.3 1.9e-11 43.9 0.1 2.0 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 EMC79925.1 - 3.8e-11 42.8 5.5 6.6e-11 42.1 3.8 1.4 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 EMC79925.1 - 1.7e-05 24.5 0.0 4.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Zn-ribbon_8 PF09723.5 EMC79925.1 - 1.8 8.5 5.4 16 5.5 2.8 2.8 1 1 2 3 3 3 0 Zinc ribbon domain DZR PF12773.2 EMC79925.1 - 4 7.3 6.6 3 7.7 2.6 2.2 2 1 0 2 2 2 0 Double zinc ribbon SH3_9 PF14604.1 EMC79926.1 - 7.8e-42 140.6 0.9 7.3e-15 54.2 0.1 4.0 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 EMC79926.1 - 9.7e-40 133.7 0.6 5.1e-12 44.9 0.0 4.2 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.12 EMC79926.1 - 3.4e-32 109.7 0.3 9.2e-13 47.4 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.11 EMC79926.1 - 8.7e-23 79.4 0.6 2.2e-22 78.1 0.4 1.7 1 0 0 1 1 1 1 Sorbin homologous domain MitMem_reg PF13012.1 EMC79927.1 - 2e-21 76.1 0.1 3.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMC79927.1 - 3.5e-14 52.5 0.7 5.8e-14 51.8 0.5 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Annexin PF00191.15 EMC79928.1 - 6.6e-99 323.8 8.6 8.3e-28 96.0 0.4 4.1 4 0 0 4 4 4 4 Annexin Metallophos PF00149.23 EMC79929.1 - 3.1e-42 144.2 0.4 4.9e-42 143.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Calsarcin PF05556.6 EMC79931.1 - 6e-89 297.8 0.0 6.8e-89 297.7 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) PDZ PF00595.19 EMC79932.1 - 7.8e-11 42.0 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Calsarcin PF05556.6 EMC79932.1 - 2.6e-06 26.8 16.3 0.022 13.9 0.1 4.2 3 2 1 4 4 4 3 Calcineurin-binding protein (Calsarcin) Sec23_trunk PF04811.10 EMC79933.1 - 2.6e-90 302.0 0.1 3.7e-90 301.5 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC79933.1 - 4.5e-26 90.2 0.0 8.4e-26 89.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMC79933.1 - 2.2e-19 69.7 0.1 1.4e-18 67.1 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMC79933.1 - 1.2e-15 56.7 10.7 2.5e-15 55.7 7.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMC79933.1 - 8.3e-12 44.6 0.0 1.9e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Glyco_transf_10 PF00852.14 EMC79934.1 - 5e-71 239.0 0.0 6.1e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Hormone_3 PF00159.13 EMC79934.1 - 0.13 12.3 0.7 8 6.5 0.1 2.9 2 1 0 2 2 2 0 Pancreatic hormone peptide CHCH PF06747.8 EMC79935.1 - 2.7e-09 36.6 2.6 3.8e-09 36.2 1.8 1.2 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EMC79935.1 - 0.00066 19.7 0.4 0.00081 19.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) SRCR PF00530.13 EMC79936.1 - 8.3e-113 369.3 31.6 5.6e-33 113.2 1.2 4.5 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Trypsin PF00089.21 EMC79936.1 - 2.4e-63 213.6 0.0 3.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 EMC79936.1 - 6e-25 87.3 12.1 2.1e-05 24.6 0.4 4.6 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Kringle PF00051.13 EMC79936.1 - 6.3e-09 35.8 0.7 1.5e-08 34.5 0.5 1.7 1 0 0 1 1 1 1 Kringle domain DUF1986 PF09342.6 EMC79936.1 - 0.00025 20.4 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) SapB_2 PF03489.12 EMC79936.1 - 0.018 15.0 0.0 74 3.5 0.0 4.4 4 0 0 4 4 4 0 Saposin-like type B, region 2 Defensin_1 PF00323.14 EMC79936.1 - 0.033 14.5 1.5 1.8 8.9 0.1 3.4 2 0 0 2 2 2 0 Mammalian defensin HSNSD PF12062.3 EMC79937.1 - 8.8e-260 862.1 0.0 1.3e-259 861.5 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 EMC79937.1 - 3e-45 154.5 0.0 4.6e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC79937.1 - 0.017 16.0 1.3 0.07 14.0 0.2 2.6 2 1 0 2 2 2 0 Sulfotransferase family Pkinase PF00069.20 EMC79938.1 - 5.5e-60 202.6 0.0 2.4e-49 167.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC79938.1 - 9.4e-24 83.8 0.0 5.1e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Trypsin PF00089.21 EMC79939.1 - 3.8e-68 229.3 1.8 5e-68 228.9 1.3 1.1 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 EMC79939.1 - 3.8e-18 65.3 3.9 1e-17 63.9 2.7 1.8 1 0 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.1 EMC79939.1 - 0.00034 20.5 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 EMC79939.1 - 0.0033 17.5 6.5 0.0033 17.5 4.5 2.9 3 0 0 3 3 3 1 EGF-like domain DUF316 PF03761.10 EMC79939.1 - 0.02 14.2 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF316) DUF1986 PF09342.6 EMC79939.1 - 0.02 14.2 0.1 0.038 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Adap_comp_sub PF00928.16 EMC79940.1 - 1.3e-64 217.8 0.0 1.6e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMC79940.1 - 0.00013 21.7 0.2 0.00024 20.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 EMC79940.1 - 0.074 12.6 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain PfkB PF00294.19 EMC79941.1 - 6.8e-78 261.8 0.2 7.9e-78 261.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMC79941.1 - 0.018 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MOZ_SAS PF01853.13 EMC79942.1 - 2.5e-43 147.5 0.1 1.5e-40 138.4 0.0 2.4 1 1 1 2 2 2 2 MOZ/SAS family Acetyltransf_1 PF00583.19 EMC79942.1 - 0.18 11.8 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DSPc PF00782.15 EMC79943.1 - 2.6e-30 104.6 0.0 3.5e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC79943.1 - 0.0001 21.7 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EMC79943.1 - 0.0013 17.7 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DSPn PF14671.1 EMC79943.1 - 0.0074 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.1 EMC79943.1 - 0.028 14.4 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC79943.1 - 0.046 13.9 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.9 EMC79943.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Thiolase_C PF02803.13 EMC79943.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Thiolase, C-terminal domain DSPc PF00782.15 EMC79944.1 - 6.2e-27 93.7 0.0 7.4e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC79944.1 - 4e-05 23.0 0.0 5.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC79944.1 - 0.035 14.3 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 EMC79945.1 - 7.5e-28 96.7 0.0 8.7e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC79945.1 - 0.0011 18.3 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC79946.1 - 6.9e-27 93.6 0.0 8.2e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC79946.1 - 9e-05 21.9 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EMC79946.1 - 0.012 14.3 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Init_tRNA_PT PF04179.7 EMC79946.1 - 0.06 12.2 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase NMT PF01233.14 EMC79946.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain PAP2_C PF14360.1 EMC79947.1 - 3.6e-28 97.6 10.0 3.6e-28 97.6 6.9 2.9 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.25 EMC79947.1 - 2e-11 43.8 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC79947.1 - 3.8e-06 26.6 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mpv17_PMP22 PF04117.7 EMC79947.1 - 0.018 14.6 0.1 0.059 13.0 0.1 2.0 1 0 0 1 1 1 0 Mpv17 / PMP22 family SAM_PNT PF02198.11 EMC79947.1 - 0.023 14.4 0.2 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain PAP2 PF01569.16 EMC79947.1 - 0.078 12.6 13.8 0.25 11.0 9.4 2.1 1 1 0 1 1 1 0 PAP2 superfamily PAP2_3 PF14378.1 EMC79947.1 - 1.5 8.2 13.0 2 7.8 8.0 2.0 1 1 1 2 2 2 0 PAP2 superfamily DUF202 PF02656.10 EMC79947.1 - 8.9 6.6 10.8 44 4.3 2.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Porin_3 PF01459.17 EMC79948.1 - 2.1e-79 266.6 5.4 2.4e-79 266.4 3.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Methyltransf_3 PF01596.12 EMC79949.1 - 3.2e-78 261.4 0.0 3.7e-78 261.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMC79949.1 - 1.5e-14 54.6 0.0 2.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC79949.1 - 3.3e-08 33.2 0.1 4.9e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC79949.1 - 9.3e-07 29.4 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC79949.1 - 0.00018 21.1 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EMC79949.1 - 0.001 18.2 0.0 0.0025 16.9 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EMC79949.1 - 0.021 15.3 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMC79949.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMC79949.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain UPF0146 PF03686.8 EMC79949.1 - 0.13 12.1 0.1 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) LRR_9 PF14580.1 EMC79950.1 - 1e-05 25.1 4.2 4.6e-05 23.0 2.9 2.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EMC79950.1 - 0.063 12.9 15.6 0.17 11.5 4.2 3.7 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC79950.1 - 1.4 8.7 12.4 2.4 7.9 6.0 3.0 2 1 0 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 EMC79950.1 - 3.2 8.3 11.4 48 4.7 0.1 4.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EMC79950.1 - 3.8 7.8 12.6 1.8 8.8 0.2 3.6 4 0 0 4 4 4 0 Leucine Rich repeat BK_channel_a PF03493.13 EMC79951.1 - 1.4e-29 101.9 0.0 4e-29 100.5 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 EMC79951.1 - 1.7e-16 60.0 16.1 1.7e-16 60.0 11.2 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EMC79951.1 - 1.2e-14 53.7 2.9 3.3e-14 52.3 2.0 1.8 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.13 EMC79951.1 - 4.7e-06 26.5 0.1 6.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain PDZ PF00595.19 EMC79952.1 - 1.2e-45 153.5 9.8 2.3e-13 50.1 0.0 4.6 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC79952.1 - 8.5e-24 83.2 2.8 2.7e-06 27.1 0.0 4.8 4 0 0 4 4 4 4 PDZ domain Takusan PF04822.8 EMC79952.1 - 3.2e-16 58.8 0.1 3.2e-16 58.8 0.1 5.1 3 1 3 6 6 6 1 Takusan Guanylate_kin PF00625.16 EMC79952.1 - 5.5e-13 48.7 1.2 5.5e-13 48.7 0.8 4.0 5 2 0 6 6 6 1 Guanylate kinase SH3_1 PF00018.23 EMC79952.1 - 0.03 13.7 0.0 0.072 12.4 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.12 EMC79952.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain RNA_pol_Rpb1_5 PF04998.12 EMC79953.1 - 6.2e-103 343.8 0.1 1e-102 343.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EMC79953.1 - 5.7e-102 341.4 0.7 9.2e-102 340.7 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EMC79953.1 - 1.9e-69 232.8 0.1 3.8e-69 231.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMC79953.1 - 5.6e-42 143.1 0.0 9.8e-41 139.1 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMC79953.1 - 1.7e-32 111.3 0.0 6.7e-32 109.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_S24e PF01282.14 EMC79954.1 - 5.5e-38 128.6 0.3 8.5e-38 128.0 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e DUF4519 PF15012.1 EMC79954.1 - 0.31 10.9 6.9 0.78 9.6 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ELFV_dehydrog PF00208.16 EMC79955.1 - 4.6e-55 186.8 0.0 2.6e-52 177.8 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EMC79955.1 - 7.6e-34 116.1 0.0 1.4e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AlaDh_PNT_C PF01262.16 EMC79955.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EMC79955.1 - 0.043 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SF3b10 PF07189.6 EMC79955.1 - 0.11 12.3 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) C2 PF00168.25 EMC79956.1 - 2.7e-28 97.6 0.5 2.1e-14 53.1 0.1 2.4 2 0 0 2 2 2 2 C2 domain MP PF01107.13 EMC79956.1 - 0.0055 16.1 0.1 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Viral movement protein (MP) CEP76-C2 PF15627.1 EMC79956.1 - 0.029 13.8 0.1 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 CEP76 C2 domain NT-C2 PF10358.4 EMC79956.1 - 0.042 13.3 0.6 0.11 12.0 0.2 1.8 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins ARA70 PF12489.3 EMC79958.1 - 8.2e-73 242.6 30.8 8.5e-39 132.5 4.1 5.3 5 1 0 5 5 5 3 Nuclear coactivator Vac_Fusion PF02346.11 EMC79958.1 - 0.1 12.0 1.0 0.2 11.0 0.2 1.9 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Tim17 PF02466.14 EMC79959.1 - 7.3e-19 68.0 2.3 8.2e-19 67.9 1.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family APG6 PF04111.7 EMC79959.1 - 0.17 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PARG_cat PF05028.9 EMC79960.1 - 3.8e-106 355.1 0.0 8.7e-106 353.9 0.0 1.6 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) E1_dh PF00676.15 EMC79961.1 - 4.7e-83 278.3 0.1 8e-83 277.5 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 EMC79961.1 - 4.1e-67 225.1 0.0 6.4e-67 224.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Carn_acyltransf PF00755.15 EMC79962.1 - 6.6e-215 714.6 0.0 7.6e-215 714.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Whib PF02467.11 EMC79962.1 - 0.051 13.8 1.9 3.8 7.8 0.2 2.9 3 0 0 3 3 3 0 Transcription factor WhiB LRR_8 PF13855.1 EMC79963.1 - 3.5e-29 100.3 7.4 3e-12 46.0 0.6 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC79963.1 - 3.1e-14 52.2 14.0 4.5e-06 26.1 0.6 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.11 EMC79963.1 - 3.3e-10 39.6 0.0 5.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 EMC79963.1 - 4.5e-10 38.1 1.5 0.13 12.3 0.0 4.8 4 0 0 4 4 4 3 Leucine Rich Repeat fn3 PF00041.16 EMC79963.1 - 2.6e-07 30.6 0.0 9.1e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III domain LRR_7 PF13504.1 EMC79963.1 - 1.6e-06 27.3 7.9 0.14 12.4 0.3 4.6 4 0 0 4 4 4 3 Leucine rich repeat Ig_2 PF13895.1 EMC79963.1 - 1.5e-05 24.9 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 EMC79963.1 - 0.00066 19.4 1.3 1.4 9.2 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich repeat ig PF00047.20 EMC79963.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC79963.1 - 0.0082 16.6 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_8 PF13855.1 EMC79964.1 - 2.1e-36 123.4 12.1 4.5e-15 55.1 0.6 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC79964.1 - 1.8e-18 65.7 5.6 9.2e-09 34.7 0.2 3.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC79964.1 - 1.3e-14 51.9 2.8 0.0065 16.3 0.0 5.8 5 0 0 5 5 5 4 Leucine Rich Repeat I-set PF07679.11 EMC79964.1 - 5.2e-12 45.4 0.0 9.6e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC79964.1 - 2.1e-09 37.3 0.0 4.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC79964.1 - 9.5e-09 35.6 0.1 3.3e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 EMC79964.1 - 1.3e-07 30.6 9.5 0.079 13.2 0.1 6.1 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EMC79964.1 - 6.6e-06 25.6 3.8 0.035 14.1 0.2 4.4 4 0 0 4 4 4 1 Leucine Rich repeat V-set PF07686.12 EMC79964.1 - 0.00021 21.1 0.0 0.00089 19.1 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC79964.1 - 0.00073 19.6 0.2 0.0046 17.0 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 EMC79964.1 - 0.0032 15.8 0.0 0.0047 15.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Bax1-I PF01027.15 EMC79965.1 - 4.3e-39 134.2 15.0 4.3e-39 134.2 10.4 1.3 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 EMC79965.1 - 5.8e-14 51.9 11.5 1.1e-10 41.1 1.1 3.4 1 1 2 3 3 3 2 Bax inhibitor 1 like DUF2301 PF10063.4 EMC79965.1 - 0.087 13.0 0.4 0.26 11.5 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) Neuregulin PF02158.10 EMC79966.1 - 1.6e-10 40.3 0.8 1.6e-10 40.3 0.6 2.1 2 1 0 2 2 2 1 Neuregulin family DUF1049 PF06305.6 EMC79966.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) DUF4205 PF13898.1 EMC79967.1 - 1.9e-140 467.5 0.1 2.7e-140 466.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) UbiA PF01040.13 EMC79968.1 - 1.8e-34 119.1 12.6 2.2e-34 118.8 8.7 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyco_hydro_79n PF03662.9 EMC79969.1 - 1.9e-22 79.2 0.1 8.5e-22 77.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain DEAD PF00270.24 EMC79970.1 - 1.8e-17 63.3 1.2 4.3e-16 58.8 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC79970.1 - 1.1e-09 37.9 0.0 3.3e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EMC79970.1 - 1.2e-06 28.5 0.0 3.7e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 EMC79970.1 - 4.6e-06 26.5 0.1 1.9e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4332 PF14229.1 EMC79970.1 - 0.0044 16.9 0.3 0.012 15.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) DNA_pol_lambd_f PF10391.4 EMC79970.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Ribosomal_S18 PF01084.15 EMC79971.1 - 5.8e-22 77.3 0.0 1.6e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S18 Rubella_E1 PF05748.6 EMC79971.1 - 0.039 12.5 0.0 0.044 12.3 0.0 1.0 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 Cluap1 PF10234.4 EMC79972.1 - 0.0033 16.6 1.3 0.0033 16.6 0.9 1.7 2 0 0 2 2 2 1 Clusterin-associated protein-1 Tropomyosin PF00261.15 EMC79972.1 - 0.0049 16.0 3.5 0.0049 16.0 2.4 1.8 2 0 0 2 2 2 1 Tropomyosin DUF948 PF06103.6 EMC79972.1 - 0.037 13.9 1.5 0.13 12.1 1.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CAMP_factor PF07373.6 EMC79972.1 - 0.042 13.3 0.3 0.071 12.6 0.2 1.3 1 0 0 1 1 1 0 CAMP factor (Cfa) DASH_Dad3 PF08656.5 EMC79972.1 - 0.18 11.5 2.5 0.27 10.9 0.7 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF573 PF04504.9 EMC79972.1 - 0.54 10.5 5.5 5 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF573 IncA PF04156.9 EMC79972.1 - 1.6 8.3 12.0 0.13 11.8 3.6 2.1 2 0 0 2 2 2 0 IncA protein Acyltransferase PF01553.16 EMC79973.1 - 4.1e-11 42.4 0.0 6.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3612 PF12268.3 EMC79973.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Acyltransferase PF01553.16 EMC79974.1 - 2.9e-11 42.9 0.0 5.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3612 PF12268.3 EMC79974.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) zf-B_box PF00643.19 EMC79975.1 - 2.6e-07 30.4 13.5 2.6e-07 30.4 9.4 3.7 3 1 0 3 3 3 2 B-box zinc finger SPRY PF00622.23 EMC79976.1 - 0.0046 17.0 0.2 0.14 12.2 0.2 2.4 1 1 0 1 1 1 1 SPRY domain Macoilin PF09726.4 EMC79976.1 - 0.22 9.7 5.4 0.3 9.3 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF612 PF04747.7 EMC79976.1 - 0.31 9.8 3.1 0.46 9.3 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF612 zf-C3HC4_2 PF13923.1 EMC79977.1 - 2.7e-12 46.5 9.3 2.7e-12 46.5 6.4 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC79977.1 - 2.8e-11 43.0 11.3 2.8e-11 43.0 7.8 3.2 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC79977.1 - 1.5e-10 40.6 7.5 1.5e-10 40.6 5.2 2.9 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC79977.1 - 2.3e-10 39.9 9.6 2.3e-10 39.9 6.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 EMC79977.1 - 2.5e-09 36.8 1.3 2.5e-09 36.8 0.9 4.3 5 0 0 5 5 5 1 B-box zinc finger zf-RING_5 PF14634.1 EMC79977.1 - 4.3e-09 35.9 8.2 4.3e-09 35.9 5.7 3.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC79977.1 - 7e-09 35.2 5.5 7e-09 35.2 3.8 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC79977.1 - 7.8e-09 35.1 3.6 7.8e-09 35.1 2.5 3.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-Nse PF11789.3 EMC79977.1 - 4.6e-05 22.8 4.1 0.00014 21.3 2.9 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EMC79977.1 - 0.00048 19.9 1.5 0.00048 19.9 1.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EMC79977.1 - 0.00089 19.1 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 EMC79977.1 - 0.0012 18.8 4.9 0.0012 18.8 3.4 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EMC79977.1 - 0.0048 16.6 1.7 0.017 14.9 1.2 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein HrpJ PF07201.6 EMC79977.1 - 0.0077 16.2 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 HrpJ-like domain DUF2383 PF09537.5 EMC79977.1 - 0.0079 16.4 2.0 0.013 15.6 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF4164 PF13747.1 EMC79977.1 - 0.0092 16.0 1.7 0.015 15.4 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) CtIP_N PF10482.4 EMC79977.1 - 0.021 14.6 3.3 0.049 13.4 2.3 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF349 PF03993.7 EMC79977.1 - 0.029 14.5 3.4 0.056 13.6 2.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Racemase_4 PF13615.1 EMC79977.1 - 0.037 14.2 0.5 0.085 13.1 0.4 1.5 1 0 0 1 1 1 0 Putative alanine racemase GAGA PF09237.6 EMC79977.1 - 0.081 12.5 3.8 0.51 9.9 1.2 2.7 2 0 0 2 2 2 0 GAGA factor Gon7 PF08738.5 EMC79977.1 - 0.096 12.6 4.2 0.069 13.1 1.5 1.8 2 0 0 2 2 2 0 Gon7 family DUF948 PF06103.6 EMC79977.1 - 0.11 12.3 9.6 0.19 11.6 3.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 EMC79977.1 - 4.5 6.2 14.1 0.054 12.5 4.6 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 EMC79977.1 - 6.3 5.7 8.4 12 4.8 5.3 1.7 2 0 0 2 2 2 0 TMPIT-like protein Sulfate_transp PF00916.15 EMC79978.1 - 4.2e-79 265.4 8.5 7.3e-79 264.6 5.9 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMC79978.1 - 7.2e-32 108.9 2.4 7.2e-32 108.9 1.7 3.0 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMC79978.1 - 2.3e-28 97.9 0.0 4.2e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EMC79978.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 STAS domain Sulfate_transp PF00916.15 EMC79979.1 - 5.2e-75 252.0 7.4 9.1e-75 251.2 5.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMC79979.1 - 4.1e-27 93.6 0.6 4.1e-27 93.6 0.4 3.6 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMC79979.1 - 1.2e-24 85.9 0.0 2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF543 PF04418.7 EMC79979.1 - 0.34 10.8 2.7 0.4 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) 7tm_1 PF00001.16 EMC79980.1 - 2.2e-73 246.5 14.2 3.6e-73 245.8 9.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) F-box PF00646.28 EMC79981.1 - 9.6e-05 21.9 0.1 0.00029 20.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC79981.1 - 0.00093 18.8 0.3 0.0023 17.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like Zip PF02535.17 EMC79981.1 - 6.9 5.5 5.5 14 4.5 3.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter IRF PF00605.12 EMC79982.1 - 2.6e-46 155.9 1.2 5e-46 155.0 0.8 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IL5 PF02025.10 EMC79983.1 - 0.00083 19.3 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 Interleukin 5 AAA_23 PF13476.1 EMC79984.1 - 2.6e-18 67.0 22.5 2.6e-18 67.0 15.6 9.3 1 1 3 4 4 4 1 AAA domain Rad50_zn_hook PF04423.9 EMC79984.1 - 1.1e-15 56.7 0.0 1.1e-15 56.7 0.0 6.6 6 0 0 6 6 6 1 Rad50 zinc hook motif SbcCD_C PF13558.1 EMC79984.1 - 2.6e-12 46.4 0.0 7.7e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EMC79984.1 - 3.4e-09 37.0 17.4 3.5e-05 23.9 0.0 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EMC79984.1 - 7.8e-06 25.2 0.0 7.8e-06 25.2 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EMC79984.1 - 0.00012 20.6 142.3 0.0044 15.5 0.0 7.8 3 1 5 8 8 8 4 AAA domain AAA_29 PF13555.1 EMC79984.1 - 0.0046 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EMC79984.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2_4 PF13894.1 EMC79984.1 - 0.32 11.4 2.3 0.73 10.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger IL4 PF00727.13 EMC79985.1 - 6.2e-08 32.5 0.8 9.9e-07 28.6 0.5 2.0 1 1 0 1 1 1 1 Interleukin 4 Kinesin PF00225.18 EMC79986.1 - 1.3e-120 402.1 0.1 1.3e-120 402.1 0.0 1.8 2 1 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 EMC79986.1 - 0.0035 17.4 2.8 1.1 9.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain Cyclin_N PF00134.18 EMC79987.1 - 3.1e-09 36.4 0.1 5.9e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Septin PF00735.13 EMC79988.1 - 1.6e-96 322.6 2.3 1.6e-96 322.6 1.6 2.0 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMC79988.1 - 8.8e-06 25.6 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC79988.1 - 0.00057 19.3 4.5 2 7.8 0.3 3.3 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EMC79988.1 - 0.00064 19.7 0.8 0.0048 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EMC79988.1 - 0.00072 18.7 0.3 0.0034 16.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMC79988.1 - 0.0011 19.1 0.3 0.0052 16.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EMC79988.1 - 0.0021 17.5 1.5 0.0037 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EMC79988.1 - 0.0049 16.3 3.1 0.074 12.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.17 EMC79988.1 - 0.0054 16.1 0.9 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Ras family IMD PF08397.6 EMC79988.1 - 0.018 14.3 14.6 0.039 13.2 10.1 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain ABC_tran PF00005.22 EMC79988.1 - 0.021 15.1 0.1 0.021 15.1 0.1 2.5 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EMC79988.1 - 0.027 14.6 0.0 0.08 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EMC79988.1 - 0.036 13.6 4.9 0.065 12.8 3.4 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMC79988.1 - 0.056 12.3 0.0 0.056 12.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 EMC79988.1 - 0.098 13.1 0.1 0.098 13.1 0.1 2.6 2 2 0 2 2 2 0 Miro-like protein Exonuc_VII_L PF02601.10 EMC79988.1 - 0.12 11.5 12.4 0.22 10.6 8.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_29 PF13555.1 EMC79988.1 - 0.12 11.9 0.1 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FliT PF05400.8 EMC79988.1 - 0.31 11.4 9.2 0.81 10.1 6.3 1.7 1 0 0 1 1 1 0 Flagellar protein FliT AAA_32 PF13654.1 EMC79988.1 - 0.38 9.3 17.6 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EMC79988.1 - 0.68 9.7 0.0 0.68 9.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EMC79988.1 - 1.2 8.9 8.8 7.2 6.4 0.0 3.2 2 1 1 3 3 3 0 Dynamin family DUF3287 PF11690.3 EMC79988.1 - 2 8.5 11.7 11 6.0 8.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Fzo_mitofusin PF04799.8 EMC79988.1 - 2.7 7.3 10.0 1.3 8.3 5.2 1.8 2 0 0 2 2 2 0 fzo-like conserved region ATP_bind_1 PF03029.12 EMC79988.1 - 5.5 6.4 7.1 13 5.2 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein UcrQ PF02939.11 EMC79989.1 - 8.6e-35 118.4 0.1 9.3e-35 118.3 0.0 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EMC79989.1 - 0.00093 19.2 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2741) LEAP-2 PF07359.6 EMC79990.1 - 1.1e-24 85.7 2.8 1.2e-24 85.6 2.0 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) HSP70 PF00012.15 EMC79991.1 - 1.8e-207 690.0 17.5 1.9e-200 666.7 0.1 3.0 1 1 2 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 EMC79991.1 - 1e-09 37.4 0.0 2.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 EMC79991.1 - 0.0018 18.0 1.2 1.3 8.8 0.0 3.8 4 0 0 4 4 4 1 Cell division protein FtsA Clr5 PF14420.1 EMC79991.1 - 1.5 8.8 7.2 0.13 12.1 0.3 2.6 3 0 0 3 3 3 0 Clr5 domain DUF853 PF05872.7 EMC79991.1 - 9.5 4.4 10.3 0.9 7.8 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) RWD PF05773.17 EMC79992.1 - 2.2e-24 85.4 0.2 5.4e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 RWD domain IBR PF01485.16 EMC79992.1 - 6.8e-17 61.1 18.9 2.2e-10 40.2 2.5 4.7 3 1 1 4 4 4 2 IBR domain zf-RING_5 PF14634.1 EMC79992.1 - 0.00034 20.2 15.5 0.00034 20.2 10.7 3.6 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.1 EMC79992.1 - 0.0018 18.0 11.6 0.0018 18.0 8.0 4.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC79992.1 - 0.018 15.0 13.8 0.018 15.0 9.6 4.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RWD PF05773.17 EMC79993.1 - 3.6e-24 84.8 0.0 7e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EMC79993.1 - 5e-18 64.7 16.2 2.1e-10 40.3 2.5 4.6 3 1 1 4 4 4 2 IBR domain zf-RING_5 PF14634.1 EMC79993.1 - 0.00033 20.3 15.5 0.00033 20.3 10.7 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC79993.1 - 0.0017 18.1 11.6 0.0017 18.1 8.0 4.1 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC79993.1 - 0.018 15.0 13.8 0.018 15.0 9.6 4.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Glucosamine_iso PF01182.15 EMC79994.1 - 6.9e-19 68.3 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF4130 PF13566.1 EMC79994.1 - 0.055 13.0 0.1 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4130 DUF2370 PF10176.4 EMC79995.1 - 7.4e-46 156.3 9.0 2.7e-36 125.0 0.1 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF2370) Herpes_UL56 PF04534.7 EMC79995.1 - 0.03 14.0 0.5 0.042 13.5 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF872 PF05915.7 EMC79995.1 - 0.22 11.4 1.2 0.4 10.5 0.5 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF373 PF04123.8 EMC79995.1 - 1.1 8.2 3.0 2.4 7.1 2.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF373) TMEM52 PF14979.1 EMC79995.1 - 10 6.0 6.7 4.3 7.2 0.3 2.4 2 1 0 2 2 2 0 Transmembrane 52 Sprouty PF05210.8 EMC79996.1 - 1.3e-34 118.4 33.0 2.8e-34 117.3 21.9 2.1 2 0 0 2 2 2 1 Sprouty protein (Spry) FGF PF00167.13 EMC79997.1 - 2.4e-40 137.0 0.0 3e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 EMC79997.1 - 0.00035 20.6 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 Fascin domain GCR PF02155.10 EMC79999.1 - 4.7e-173 575.1 3.1 5.9e-173 574.8 2.2 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.25 EMC79999.1 - 2e-30 105.4 4.5 2.9e-30 104.9 3.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC79999.1 - 2.3e-28 98.1 12.9 4.3e-28 97.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Collagen PF01391.13 EMC80000.1 - 0.0028 17.1 10.4 1.1 8.8 1.2 3.8 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF4021 PF13213.1 EMC80000.1 - 0.36 10.4 1.4 99 2.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4021) Plasmodium_HRP PF05403.6 EMC80000.1 - 1.4 8.4 6.6 12 5.4 4.6 2.1 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Yip1 PF04893.12 EMC80001.1 - 3.1e-10 39.8 15.8 4.3e-10 39.3 11.0 1.3 1 0 0 1 1 1 1 Yip1 domain BTB_2 PF02214.17 EMC80002.1 - 1.2e-15 57.4 0.0 2.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DnaJ_CXXCXGXG PF00684.14 EMC80004.1 - 0.096 12.7 14.5 0.23 11.5 7.5 2.5 1 1 1 2 2 2 0 DnaJ central domain SH3_1 PF00018.23 EMC80005.1 - 3.5e-21 74.3 0.0 3e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC80005.1 - 4.9e-20 70.8 0.0 2.3e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMC80005.1 - 1.7e-18 65.7 0.0 5.9e-12 44.8 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain zf-C3HC4_2 PF13923.1 EMC80005.1 - 1.7e-10 40.7 9.4 3.6e-10 39.6 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC80005.1 - 5.3e-10 38.7 9.5 1e-09 37.8 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC80005.1 - 6.1e-09 35.4 8.9 1.3e-08 34.4 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC80005.1 - 1.5e-08 34.3 8.5 2.9e-08 33.4 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EMC80005.1 - 5.5e-08 32.4 8.2 1.1e-07 31.4 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EMC80005.1 - 5.2e-07 29.2 9.4 9.5e-07 28.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMC80005.1 - 3.8e-06 26.3 7.5 7.9e-06 25.3 5.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMC80005.1 - 0.00013 21.7 9.8 0.00025 20.8 6.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EMC80005.1 - 0.02 14.9 3.8 0.039 14.0 2.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 EMC80005.1 - 0.043 13.3 7.5 0.08 12.4 5.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMC80005.1 - 0.29 10.6 8.1 0.93 9.0 4.5 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.6 EMC80005.1 - 0.97 9.3 8.2 0.57 10.0 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 EMC80005.1 - 1.5 8.7 5.3 3 7.7 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.7 EMC80005.1 - 2.1 8.1 8.1 4.2 7.2 5.6 1.5 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.2 EMC80005.1 - 2.7 7.9 9.1 7.5 6.4 5.8 2.1 2 0 0 2 2 2 0 Double zinc ribbon tRNA-synt_1 PF00133.17 EMC80006.1 - 3.9e-38 130.8 0.0 5.4e-24 84.1 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMC80006.1 - 1.7e-20 73.0 0.1 3.6e-10 39.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMC80006.1 - 9.9e-16 57.8 0.0 2.6e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EMC80006.1 - 1.9e-06 27.2 0.0 4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EMC80006.1 - 0.025 13.2 0.0 0.058 12.0 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (K) FF PF01846.14 EMC80007.1 - 3.5e-79 260.6 45.3 1.7e-14 53.5 1.0 6.7 6 0 0 6 6 6 6 FF domain WW PF00397.21 EMC80007.1 - 3.7e-17 61.8 26.6 4.1e-07 29.7 4.0 3.9 4 0 0 4 4 4 3 WW domain NifQ PF04891.7 EMC80007.1 - 8.5 6.5 9.8 0.81 9.8 2.6 2.5 2 0 0 2 2 2 0 NifQ Pkinase PF00069.20 EMC80008.1 - 1.3e-61 208.0 0.1 1.9e-61 207.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80008.1 - 4.1e-38 130.9 0.2 5.6e-38 130.4 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC80008.1 - 1e-13 50.9 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC80008.1 - 0.0029 17.3 0.4 0.0049 16.6 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMC80008.1 - 0.027 13.3 0.1 0.061 12.1 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Amidohydro_1 PF01979.15 EMC80009.1 - 6.8e-34 118.0 0.0 9.1e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC80009.1 - 1e-12 48.6 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMC80009.1 - 1.8e-09 37.2 2.5 3.1e-09 36.5 0.4 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_2 PF04909.9 EMC80009.1 - 1.8e-05 24.4 0.1 7.9e-05 22.3 0.0 2.0 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC80009.1 - 0.00029 20.1 0.7 0.0096 15.1 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family PX PF00787.19 EMC80010.1 - 0.044 13.5 0.4 0.068 12.9 0.3 1.2 1 0 0 1 1 1 0 PX domain TB2_DP1_HVA22 PF03134.14 EMC80012.1 - 7.5e-22 76.8 9.0 1.1e-21 76.4 6.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family JmjC PF02373.17 EMC80013.1 - 1.3e-15 57.6 0.0 3.1e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EMC80013.1 - 0.078 12.4 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Cupin domain zf-UDP PF14569.1 EMC80013.1 - 0.99 9.2 6.8 1.9 8.3 1.0 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger FYVE PF01363.16 EMC80013.1 - 6.8 6.6 11.3 0.34 10.8 3.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger 2-Hacid_dh_C PF02826.14 EMC80014.1 - 1.6e-56 190.2 0.0 2.2e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC80014.1 - 1.5e-26 92.4 0.0 1.9e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC80014.1 - 6.3e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMC80014.1 - 0.04 14.3 0.0 0.68 10.4 0.0 2.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 EMC80014.1 - 0.058 13.7 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 XdhC Rossmann domain GDNF PF02351.11 EMC80015.1 - 5.7e-34 116.4 44.1 2.7e-17 63.0 5.7 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain APC8 PF04049.8 EMC80016.1 - 3.1e-29 101.5 3.2 3.1e-29 101.5 2.2 3.0 3 1 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EMC80016.1 - 1.3e-26 91.0 35.2 5.4e-06 25.7 0.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMC80016.1 - 1.1e-24 84.3 36.4 0.00044 19.9 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EMC80016.1 - 1.3e-19 69.5 31.1 5.5e-08 32.3 0.6 7.8 5 1 3 8 8 8 6 TPR repeat TPR_8 PF13181.1 EMC80016.1 - 2e-16 58.4 30.3 0.00027 20.5 0.0 10.0 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC80016.1 - 1.5e-15 56.2 15.1 0.0086 16.6 0.0 9.4 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC80016.1 - 3.8e-12 45.0 21.6 0.021 14.6 0.1 9.0 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMC80016.1 - 1.3e-11 44.2 32.5 0.0079 16.1 1.7 8.9 4 2 7 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 EMC80016.1 - 1.7e-09 38.0 18.3 0.00026 21.5 0.0 7.9 5 3 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC80016.1 - 1.4e-08 34.9 20.3 0.14 12.5 0.0 7.3 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC80016.1 - 2.3e-08 33.5 16.5 0.043 14.0 0.0 7.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMC80016.1 - 6.8e-07 29.3 30.2 1.2 9.7 0.0 10.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC80016.1 - 2.7e-05 23.9 8.1 2.7 8.0 0.0 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC80016.1 - 2.8e-05 24.1 38.3 0.02 15.0 1.0 6.6 4 2 3 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 DUF772 PF05598.6 EMC80016.1 - 0.00014 21.7 0.1 0.00038 20.2 0.1 1.7 1 0 0 1 1 1 1 Transposase domain (DUF772) TPR_9 PF13371.1 EMC80016.1 - 0.019 14.8 6.5 0.068 13.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EMC80016.1 - 0.094 12.7 0.1 11 6.2 0.0 4.0 4 0 0 4 4 4 0 PPR repeat Pox_A_type_inc PF04508.7 EMC80017.1 - 0.059 13.1 0.0 0.059 13.1 0.0 9.8 13 1 0 13 13 13 0 Viral A-type inclusion protein repeat Anth_Ig PF05587.8 EMC80018.1 - 3.9e-48 161.6 0.3 5.7e-48 161.1 0.2 1.2 1 0 0 1 1 1 1 Anthrax receptor extracellular domain Ant_C PF05586.6 EMC80018.1 - 4.7e-40 135.9 0.8 7.8e-40 135.2 0.6 1.4 1 0 0 1 1 1 1 Anthrax receptor C-terminus region VWA PF00092.23 EMC80018.1 - 1.9e-21 76.6 0.0 2.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC80018.1 - 1.2e-15 58.0 0.0 1.6e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMC80018.1 - 2.7e-06 26.6 0.0 4.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF3328 PF11807.3 EMC80018.1 - 0.14 11.8 0.2 0.37 10.4 0.0 1.5 1 1 0 2 2 2 0 Domain of unknown function (DUF3328) Mito_carr PF00153.22 EMC80020.1 - 3.5e-69 228.5 0.6 1.8e-22 78.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4042 PF13251.1 EMC80020.1 - 0.053 12.9 0.0 0.41 10.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) zf-HC5HC2H PF13771.1 EMC80021.1 - 1e-14 54.4 4.2 1e-14 54.4 2.9 3.7 4 1 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC80021.1 - 6.3e-07 29.3 9.4 6.3e-07 29.3 6.5 3.2 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-RING_2 PF13639.1 EMC80021.1 - 1.2e-06 28.2 6.2 1.2e-06 28.2 4.3 4.6 4 1 0 4 4 4 2 Ring finger domain zf-RanBP PF00641.13 EMC80021.1 - 1 8.5 0.0 1 8.5 0.0 4.7 5 0 0 5 5 5 0 Zn-finger in Ran binding protein and others SPRY PF00622.23 EMC80022.1 - 9e-19 67.7 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.11 EMC80022.1 - 2.6e-14 52.7 3.2 5e-14 51.8 2.2 1.5 1 0 0 1 1 1 1 SOCS box zf-B_box PF00643.19 EMC80023.1 - 5.3e-09 35.8 18.8 2.2e-08 33.8 2.7 5.8 6 0 0 6 6 6 3 B-box zinc finger fn3 PF00041.16 EMC80023.1 - 3.7e-08 33.3 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Cadherin PF00028.12 EMC80024.1 - 1e-15 57.7 0.2 6e-10 39.2 0.4 2.6 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.1 EMC80024.1 - 1.7e-08 34.8 0.0 3.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1510 PF07423.6 EMC80024.1 - 0.0015 17.9 6.9 0.0023 17.3 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Glyco_hydro_16 PF00722.16 EMC80024.1 - 0.0082 15.4 0.6 0.031 13.5 0.4 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chordopox_A13L PF05961.6 EMC80024.1 - 0.027 14.4 0.0 0.096 12.6 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Asparaginase_2 PF01112.13 EMC80025.1 - 1.7e-106 355.5 0.4 2e-106 355.3 0.2 1.0 1 0 0 1 1 1 1 Asparaginase zf-GRF PF06839.7 EMC80026.1 - 4e-34 116.2 12.2 3.9e-18 65.0 2.8 3.9 4 0 0 4 4 4 2 GRF zinc finger H2TH PF06831.9 EMC80026.1 - 2.5e-13 49.5 0.0 5.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EMC80026.1 - 1.4e-06 28.6 0.2 3.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-RanBP PF00641.13 EMC80026.1 - 0.00057 18.9 2.6 0.00057 18.9 1.8 2.8 2 1 1 3 3 3 1 Zn-finger in Ran binding protein and others PDGF PF00341.12 EMC80027.1 - 5e-23 81.0 7.2 5e-23 81.0 5.0 3.2 3 0 0 3 3 3 1 PDGF/VEGF domain CXCXC PF03128.9 EMC80027.1 - 8.3e-09 34.9 49.9 0.007 16.4 2.6 8.8 8 0 0 8 8 8 5 CXCXC repeat SPC22 PF04573.7 EMC80028.1 - 5.5e-53 178.7 0.0 6.6e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit AsmA_2 PF13502.1 EMC80028.1 - 0.0043 16.4 0.1 0.0058 16.0 0.1 1.1 1 0 0 1 1 1 1 AsmA-like C-terminal region Ank_2 PF12796.2 EMC80029.1 - 9e-51 170.1 9.6 3.3e-19 68.9 0.2 2.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC80029.1 - 7.9e-44 145.3 8.1 1.7e-09 37.0 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EMC80029.1 - 6.9e-31 106.0 1.9 4.9e-10 39.6 0.0 4.9 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80029.1 - 1e-30 102.7 2.2 9.3e-07 28.5 0.1 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EMC80029.1 - 1.7e-24 85.2 6.5 1.8e-07 31.1 0.0 6.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC80029.1 - 5.5e-13 48.5 8.6 1.1e-12 47.5 5.9 1.6 1 0 0 1 1 1 1 SOCS box WD40 PF00400.27 EMC80030.1 - 8.4e-61 199.8 32.4 5.1e-11 42.0 0.1 10.9 11 0 0 11 11 11 8 WD domain, G-beta repeat Nup160 PF11715.3 EMC80030.1 - 0.00073 17.7 10.7 0.084 10.9 0.0 4.6 4 2 1 6 6 6 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EMC80030.1 - 0.31 9.7 0.1 24 3.5 0.0 2.6 3 0 0 3 3 3 0 Coatomer WD associated region DUF1546 PF07571.8 EMC80031.1 - 8.1e-12 45.1 0.0 1.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) DUF3039 PF11238.3 EMC80031.1 - 0.12 11.7 0.2 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) RNase_PH PF01138.16 EMC80032.1 - 9.4e-37 126.2 0.4 8.1e-22 77.9 0.0 3.3 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMC80032.1 - 6.6e-20 70.8 1.5 1.5e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.9 EMC80032.1 - 8.7e-10 38.7 0.2 2.5e-09 37.2 0.1 1.9 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.18 EMC80032.1 - 1.7e-07 31.2 0.0 2.2e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 S1 RNA binding domain KH_1 PF00013.24 EMC80032.1 - 0.0047 16.5 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 KH domain OAF PF14941.1 EMC80032.1 - 0.016 14.3 0.1 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, Out at first ARL2_Bind_BART PF11527.3 EMC80033.1 - 9.4e-28 96.4 4.8 9.4e-28 96.4 3.3 1.4 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Ppx-GppA PF02541.11 EMC80033.1 - 0.067 12.3 0.9 0.096 11.8 0.6 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Motilin_assoc PF04643.7 EMC80033.1 - 0.35 10.4 2.2 0.61 9.6 0.3 2.4 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide HOOK PF05622.7 EMC80034.1 - 6.5e-30 103.5 63.2 6.5e-30 103.5 43.8 4.9 1 1 3 4 4 4 2 HOOK protein GAS PF13851.1 EMC80034.1 - 0.0024 17.1 65.5 0.0033 16.6 24.6 12.6 2 1 10 13 13 13 4 Growth-arrest specific micro-tubule binding tRNA_edit PF04073.10 EMC80035.1 - 7.1e-26 90.4 0.0 9e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HTH_10 PF04967.7 EMC80035.1 - 0.076 12.6 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain GTP_EFTU PF00009.22 EMC80036.1 - 4.1e-39 133.9 2.3 3.5e-38 130.9 1.6 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMC80036.1 - 1.4e-28 98.9 0.8 1.4e-28 98.9 0.6 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMC80036.1 - 5e-11 42.5 0.1 3.9e-07 30.0 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Miro PF08477.8 EMC80036.1 - 3.5e-08 33.9 1.4 1.5e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMC80036.1 - 3.2e-07 30.3 0.1 9.3e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EMC80036.1 - 6.3e-05 22.2 0.2 0.00026 20.2 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EMC80036.1 - 0.00023 20.5 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 EMC80036.1 - 0.00054 19.2 1.1 0.0059 15.8 0.2 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMC80036.1 - 0.00095 18.4 0.1 0.0039 16.4 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B IF2_N PF04760.10 EMC80036.1 - 0.0024 17.5 1.2 0.047 13.3 0.1 2.7 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D4 PF14578.1 EMC80036.1 - 0.003 17.1 2.8 1.2 8.8 0.3 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 4 Dynamin_N PF00350.18 EMC80036.1 - 0.0039 17.0 1.1 0.81 9.4 0.0 3.2 2 1 1 3 3 3 1 Dynamin family AAA_26 PF13500.1 EMC80036.1 - 0.022 14.3 0.3 0.095 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EMC80036.1 - 0.033 13.6 0.5 0.24 10.8 0.1 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ubiquitin PF00240.18 EMC80037.1 - 6.8e-35 118.2 0.3 1.3e-34 117.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EMC80037.1 - 1.6e-28 98.2 4.0 2.9e-28 97.4 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EMC80037.1 - 1.3e-19 69.6 0.3 2.5e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC80037.1 - 1.3e-06 28.5 0.3 6.1e-06 26.3 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMC80037.1 - 0.00017 21.4 0.6 0.00034 20.4 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EMC80037.1 - 0.00018 21.2 0.2 0.00034 20.3 0.0 1.5 1 1 1 2 2 2 1 Telomere stability and silencing DUF2407 PF10302.4 EMC80037.1 - 0.0031 17.6 0.4 0.0042 17.2 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 EMC80037.1 - 0.014 13.7 2.2 0.26 9.5 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2207 PF09972.4 EMC80037.1 - 0.031 12.8 0.4 0.037 12.6 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TUG-UBL1 PF11470.3 EMC80037.1 - 0.041 13.7 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DUF2870 PF11069.3 EMC80037.1 - 0.065 13.2 0.4 0.13 12.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) WD40 PF00400.27 EMC80038.1 - 1.1e-79 259.6 75.8 3.1e-05 23.6 0.2 30.2 33 0 0 33 33 33 20 WD domain, G-beta repeat HELP PF03451.9 EMC80038.1 - 3.2e-47 157.9 3.0 9.3e-17 60.3 0.0 3.6 3 0 0 3 3 3 3 HELP motif Nucleoporin_N PF08801.6 EMC80038.1 - 2.6e-06 26.4 0.1 0.046 12.4 0.0 4.4 4 0 0 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EMC80038.1 - 7.1e-06 24.5 8.6 1.2 7.3 0.0 6.3 6 1 1 7 7 7 3 Cytochrome D1 heme domain DUF3312 PF11768.3 EMC80038.1 - 0.00019 19.8 0.0 0.046 11.9 0.0 3.8 4 1 0 4 4 4 1 Protein of unknown function (DUF3312) PD40 PF07676.7 EMC80038.1 - 0.00039 19.9 0.1 38 4.1 0.0 5.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 EMC80038.1 - 0.00052 19.4 0.0 0.64 9.5 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TruB_C PF09142.6 EMC80038.1 - 0.015 14.9 0.1 19 5.0 0.0 4.1 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal ATP-grasp PF02222.17 EMC80038.1 - 0.045 13.0 0.0 7.7 5.8 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain Acylphosphatase PF00708.13 EMC80039.1 - 8e-17 61.1 0.2 2.1e-16 59.7 0.1 1.6 1 1 0 1 1 1 1 Acylphosphatase PRKCSH PF07915.8 EMC80041.1 - 7.9e-43 145.1 16.8 1.2e-22 80.5 4.9 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EMC80041.1 - 2.9e-11 43.0 1.8 0.00015 21.3 0.0 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein Ank_2 PF12796.2 EMC80042.1 - 1.9e-56 188.3 3.6 1.5e-22 79.7 0.4 4.5 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC80042.1 - 1.3e-51 169.9 1.3 2.1e-08 33.5 0.0 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 EMC80042.1 - 4.4e-37 125.8 2.4 1e-11 44.9 0.0 6.6 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80042.1 - 3e-36 119.8 1.2 2.7e-05 23.9 0.0 8.9 9 1 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EMC80042.1 - 5.6e-33 112.2 1.9 1.3e-06 28.4 0.0 9.2 1 1 8 9 9 9 7 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC80042.1 - 6.5e-12 45.1 8.4 1.5e-11 43.9 5.8 1.7 1 0 0 1 1 1 1 SOCS box MARVEL PF01284.18 EMC80043.1 - 8.2e-11 41.9 10.3 9.6e-11 41.6 7.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain SH3_1 PF00018.23 EMC80045.1 - 1.6e-13 49.7 0.1 5.6e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMC80045.1 - 2.1e-12 46.3 0.0 4.5e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC80045.1 - 2e-09 36.8 0.0 6.6e-09 35.2 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain TRAP_alpha PF03896.11 EMC80045.1 - 1.3 7.9 12.5 0.65 8.9 5.9 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 EMC80045.1 - 8.3 6.0 11.9 2.8 7.6 4.1 2.4 2 0 0 2 2 2 0 FAM176 family Mad3_BUB1_I PF08311.7 EMC80046.1 - 4.9e-36 123.3 0.0 1.2e-35 122.0 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EMC80046.1 - 3.7e-17 62.3 0.0 7.4e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80046.1 - 7e-08 31.8 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC80046.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EMC80046.1 - 4.4 6.6 4.1 1.1 8.5 0.1 2.0 3 0 0 3 3 3 0 RIO1 family Pkinase_Tyr PF07714.12 EMC80047.1 - 1.9e-91 305.7 0.0 2.6e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC80047.1 - 1e-43 149.3 0.0 1.4e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC80047.1 - 2.4e-15 56.4 0.1 3.1e-07 30.4 0.1 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.1 EMC80047.1 - 2.7e-15 56.2 0.1 1.1e-07 31.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC80047.1 - 1.2e-10 41.1 0.0 0.00067 19.4 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC80047.1 - 5.4e-10 39.6 6.5 3.5e-06 27.4 0.3 3.5 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 EMC80047.1 - 3.7e-07 30.1 0.1 0.086 12.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Kinase-like PF14531.1 EMC80047.1 - 0.0055 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like V-set PF07686.12 EMC80047.1 - 0.0057 16.5 0.1 2.1 8.2 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin V-set domain C1-set PF07654.10 EMC80047.1 - 0.036 14.0 0.1 2.6 8.1 0.1 2.8 2 0 0 2 2 2 0 Immunoglobulin C1-set domain APH PF01636.18 EMC80047.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family cEGF PF12662.2 EMC80048.1 - 1.2e-16 59.9 21.5 1.6e-12 46.8 1.0 4.8 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_CA PF07645.10 EMC80048.1 - 6.7e-15 54.8 14.8 1.6e-09 37.5 3.8 5.2 5 1 0 5 5 5 2 Calcium-binding EGF domain Sushi PF00084.15 EMC80048.1 - 3.6e-13 49.6 14.7 2.7e-11 43.6 0.7 3.7 4 0 0 4 4 4 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 EMC80048.1 - 7.7e-11 41.9 3.7 7.7e-11 41.9 2.6 5.1 5 0 0 5 5 5 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 EMC80048.1 - 3.9e-05 23.5 1.4 3.9e-05 23.5 1.0 6.3 8 0 0 8 8 8 1 EGF-like domain EGF_3 PF12947.2 EMC80048.1 - 0.0011 18.9 25.3 0.022 14.7 2.5 5.2 4 1 1 5 5 5 3 EGF domain zf-CCCH PF00642.19 EMC80049.1 - 7.1e-10 38.3 24.0 3.7e-05 23.2 0.9 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMC80049.1 - 0.15 12.1 23.5 0.15 12.1 1.1 3.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Paramecium_SA PF01508.11 EMC80049.1 - 0.25 11.5 3.4 0.59 10.3 2.4 1.6 1 0 0 1 1 1 0 Paramecium surface antigen domain SNAP PF14938.1 EMC80050.1 - 1.8e-114 381.7 22.5 2e-114 381.5 15.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EMC80050.1 - 3.7e-10 39.5 10.4 2e-05 24.4 3.5 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC80050.1 - 3.9e-05 23.1 12.7 0.028 14.1 0.0 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC80050.1 - 0.00017 21.1 23.2 0.013 15.1 2.5 4.5 2 1 3 5 5 5 4 TPR repeat Spatacsin_C PF14649.1 EMC80050.1 - 0.00058 18.8 12.2 0.044 12.6 3.4 2.5 1 1 0 2 2 2 2 Spatacsin C-terminus TPR_10 PF13374.1 EMC80050.1 - 0.0013 18.6 4.8 1.9 8.5 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC80050.1 - 0.0029 18.1 6.5 11 6.9 0.0 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC80050.1 - 0.0063 16.8 16.2 3.2 8.4 0.3 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC80050.1 - 0.025 15.2 9.2 0.2 12.3 1.0 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC80050.1 - 0.038 13.7 20.7 0.3 10.9 0.7 5.5 4 1 0 5 5 4 0 Tetratricopeptide repeat NSF PF02071.15 EMC80050.1 - 0.15 12.6 39.5 0.53 11.0 1.8 8.9 8 1 1 9 9 8 0 Aromatic-di-Alanine (AdAR) repeat AF0941-like PF14591.1 EMC80050.1 - 0.28 11.2 3.6 0.4 10.7 0.4 2.4 2 1 0 2 2 2 0 AF0941-like Foie-gras_1 PF11817.3 EMC80050.1 - 0.37 10.2 10.2 0.67 9.3 4.7 2.9 2 1 0 2 2 2 0 Foie gras liver health family 1 RPN7 PF10602.4 EMC80050.1 - 0.5 9.7 8.1 0.54 9.6 3.4 2.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_19 PF14559.1 EMC80050.1 - 0.57 10.5 12.8 0.1 12.9 2.0 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC80050.1 - 0.87 9.6 27.2 1.5 8.8 0.6 6.1 8 0 0 8 8 5 0 Tetratricopeptide repeat Sel1 PF08238.7 EMC80050.1 - 0.98 10.1 14.4 3.4 8.4 0.2 4.8 5 1 1 6 6 5 0 Sel1 repeat MIT PF04212.13 EMC80050.1 - 2.8 7.8 20.9 14 5.6 0.0 5.5 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain CBP PF12192.3 EMC80050.1 - 5.4 7.0 7.9 9.5 6.2 0.4 4.4 4 2 1 5 5 5 0 Fungal calcium binding protein zf-H2C2_2 PF13465.1 EMC80051.1 - 8.2e-57 186.8 68.5 4.9e-09 36.0 0.8 11.4 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.21 EMC80051.1 - 1.8e-35 119.1 88.5 0.00015 21.8 0.5 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80051.1 - 1.2e-28 97.2 79.6 6.5e-06 26.1 0.2 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger BTB PF00651.26 EMC80051.1 - 2.6e-22 78.8 2.6 4.7e-22 78.0 1.4 1.7 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 EMC80051.1 - 3.1e-11 43.0 56.6 0.043 13.9 0.0 10.5 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC80051.1 - 3.5e-08 33.3 64.1 0.049 13.8 0.0 10.4 11 0 0 11 11 11 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC80051.1 - 0.00025 20.8 73.8 0.031 14.1 2.2 11.0 10 1 0 10 10 10 5 C2H2-type zinc finger BolA PF01722.13 EMC80051.1 - 0.0018 18.1 11.5 0.2 11.6 0.5 4.4 3 1 2 5 5 5 2 BolA-like protein RRN7 PF11781.3 EMC80051.1 - 0.82 9.2 32.6 3.9 7.0 0.1 8.9 10 0 0 10 10 10 0 RNA polymerase I-specific transcription initiation factor Rrn7 LIM PF00412.17 EMC80051.1 - 6 7.0 53.1 4.2 7.5 1.4 7.4 3 1 3 7 7 7 0 LIM domain zf-C2HC_2 PF13913.1 EMC80051.1 - 9.8 5.9 44.5 0.89 9.2 0.4 7.9 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EMC80052.1 - 1.2e-43 145.2 72.3 9.5e-10 38.2 0.3 11.0 11 0 0 11 11 11 8 Zinc-finger double domain zf-C2H2 PF00096.21 EMC80052.1 - 1e-35 119.9 70.1 7.9e-06 25.9 0.5 10.8 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80052.1 - 3.7e-26 89.4 68.6 0.00023 21.2 0.6 10.8 11 0 0 11 11 11 9 C2H2-type zinc finger BTB PF00651.26 EMC80052.1 - 5.3e-24 84.3 2.6 1e-23 83.4 1.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 EMC80052.1 - 7.6e-16 57.7 42.9 0.022 14.8 0.0 10.3 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC80052.1 - 8.2e-15 54.4 53.5 0.0093 16.1 0.4 10.1 11 0 0 11 11 11 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC80052.1 - 1e-14 53.8 58.9 0.00097 18.9 0.5 11.3 10 1 0 10 10 10 8 C2H2-type zinc finger BolA PF01722.13 EMC80052.1 - 6.4e-05 22.8 1.5 2.6 8.0 0.0 4.8 2 2 1 4 4 4 2 BolA-like protein zf-C2HC_2 PF13913.1 EMC80052.1 - 8e-05 22.1 25.0 3 7.6 0.1 7.4 7 0 0 7 7 7 4 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EMC80052.1 - 0.5 10.3 0.1 0.5 10.3 0.1 10.6 10 2 1 11 11 11 0 Zinc ribbon domain Herpes_gE PF02480.11 EMC80054.1 - 0.0016 16.8 0.0 0.0017 16.6 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Alpha_GJ PF03229.8 EMC80054.1 - 0.15 12.4 11.1 0.31 11.3 7.7 1.6 1 1 0 1 1 1 0 Alphavirus glycoprotein J 7tm_1 PF00001.16 EMC80055.1 - 5.3e-68 228.9 13.4 7.1e-68 228.5 9.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC80055.1 - 1.7e-15 56.8 3.9 2.2e-15 56.5 2.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC80055.1 - 1.2e-07 31.1 3.9 1.8e-07 30.5 2.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 EMC80055.1 - 0.00082 18.5 5.4 0.008 15.3 0.0 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 EMC80055.1 - 0.0064 15.6 6.6 0.0046 16.1 2.7 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Herpes_US9 PF06072.6 EMC80055.1 - 0.07 12.9 0.6 0.07 12.9 0.4 2.8 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 Alg6_Alg8 PF03155.10 EMC80055.1 - 0.44 9.3 8.5 0.028 13.2 0.7 2.0 2 0 0 2 2 2 0 ALG6, ALG8 glycosyltransferase family Homeobox PF00046.24 EMC80057.1 - 2.9e-17 62.0 0.8 6.8e-17 60.8 0.6 1.6 1 0 0 1 1 1 1 Homeobox domain XRN_N PF03159.13 EMC80058.1 - 5.8e-105 349.9 0.0 1.2e-104 348.9 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Rap_GAP PF02145.10 EMC80059.1 - 7.3e-65 217.8 0.0 1.2e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Pyr_redox_2 PF07992.9 EMC80060.1 - 3.8e-05 23.6 0.0 0.00015 21.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC80060.1 - 0.00025 21.1 0.0 0.061 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HAT PF02184.11 EMC80061.1 - 7.7e-35 118.3 74.6 1.5e-09 37.4 0.2 15.2 14 2 0 14 14 14 8 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 EMC80061.1 - 8.2e-14 51.8 8.3 0.0067 17.0 0.0 7.8 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC80061.1 - 8.2e-14 50.8 15.0 1.4 9.8 0.0 11.3 7 3 6 13 13 12 3 Tetratricopeptide repeat Suf PF05843.9 EMC80061.1 - 2.7e-09 37.1 39.7 0.0003 20.6 3.1 5.5 2 1 3 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EMC80061.1 - 1.2e-07 31.9 6.9 0.026 14.8 0.0 7.2 6 1 4 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC80061.1 - 0.00013 21.8 9.7 0.012 15.7 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EMC80061.1 - 0.0013 17.7 45.4 0.022 13.6 2.3 6.2 2 2 3 5 5 5 3 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.6 EMC80061.1 - 0.0021 17.7 1.3 0.0021 17.7 0.9 7.7 6 2 3 10 10 10 1 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.1 EMC80061.1 - 0.01 15.5 8.3 2.4 8.1 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC80061.1 - 0.059 13.3 23.3 1.6 8.8 0.2 8.5 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC80061.1 - 3 7.8 26.8 3.2 7.7 0.2 7.5 9 2 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC80061.1 - 5.3 7.0 18.7 4.3 7.3 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Na_Ca_ex PF01699.19 EMC80062.1 - 2.3e-55 186.0 34.7 3.8e-31 107.5 7.8 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Herpes_LMP1 PF05297.6 EMC80062.1 - 0.0045 15.9 0.5 0.0045 15.9 0.4 3.2 3 0 0 3 3 3 1 Herpesvirus latent membrane protein 1 (LMP1) TFIIA PF03153.8 EMC80062.1 - 0.0063 16.4 4.9 0.0085 16.0 3.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 EMC80062.1 - 0.089 13.1 3.0 0.063 13.5 0.8 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EMC80062.1 - 0.41 10.8 10.3 0.88 9.8 7.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EMC80062.1 - 0.51 9.5 7.0 0.8 8.8 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 EMC80062.1 - 0.98 9.2 6.3 0.65 9.7 2.7 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EMC80062.1 - 1.5 8.2 12.1 1 8.8 6.3 1.9 2 0 0 2 2 2 0 Nucleoplasmin SPC25 PF06703.6 EMC80062.1 - 1.6 8.2 6.5 1.4 8.4 0.4 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Nop14 PF04147.7 EMC80062.1 - 2 6.2 10.0 2.8 5.7 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EMC80062.1 - 3.4 6.5 5.7 6.7 5.6 4.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.7 EMC80062.1 - 3.6 6.7 11.2 5.2 6.2 7.8 1.1 1 0 0 1 1 1 0 SDA1 AF1Q PF15017.1 EMC80062.1 - 5 7.1 11.9 11 6.0 8.3 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator CobT PF06213.7 EMC80062.1 - 5.7 5.9 10.8 8.8 5.3 7.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EMC80062.1 - 6.2 5.1 12.4 8.5 4.7 8.6 1.1 1 0 0 1 1 1 0 Daxx Family DNA_pol_phi PF04931.8 EMC80062.1 - 6.2 4.4 21.5 9 3.9 14.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF843 PF05814.6 EMC80062.1 - 6.2 6.6 8.6 0.64 9.8 1.0 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Drf_FH1 PF06346.7 EMC80063.1 - 0.027 13.9 59.7 0.044 13.2 41.4 1.4 1 1 0 1 1 1 0 Formin Homology Region 1 Cytadhesin_P30 PF07271.6 EMC80063.1 - 0.045 13.0 25.6 0.13 11.4 17.7 1.7 1 1 0 1 1 1 0 Cytadhesin P30/P32 VPS9 PF02204.13 EMC80065.1 - 6.5e-24 83.9 0.9 1.3e-23 82.9 0.1 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain SH2 PF00017.19 EMC80065.1 - 0.0017 18.0 0.0 0.0069 16.1 0.0 2.1 2 0 0 2 2 2 1 SH2 domain RelB PF04221.7 EMC80065.1 - 0.08 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 RelB antitoxin Sushi PF00084.15 EMC80067.1 - 2.5e-10 40.5 0.2 2.5e-10 40.5 0.1 3.1 2 2 0 2 2 2 1 Sushi domain (SCR repeat) Lectin_C PF00059.16 EMC80067.1 - 2.8e-07 31.1 0.8 2.8e-07 31.1 0.6 2.0 2 0 0 2 2 2 1 Lectin C-type domain Xlink PF00193.12 EMC80068.1 - 9.1e-67 221.1 3.1 3.7e-35 119.8 0.5 2.5 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 EMC80068.1 - 2.2e-14 53.3 0.4 1.2e-13 50.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain XRCC4 PF06632.7 EMC80069.1 - 9.1e-67 225.3 4.9 1e-66 225.1 3.4 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF927 PF06048.6 EMC80069.1 - 0.054 12.7 0.1 0.069 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) IncA PF04156.9 EMC80069.1 - 0.096 12.2 3.6 0.11 12.0 2.5 1.3 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 EMC80069.1 - 0.14 11.9 0.4 0.14 11.9 0.2 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Sds3 PF08598.6 EMC80069.1 - 1.6 8.2 7.1 2.8 7.4 4.8 1.5 1 1 0 1 1 1 0 Sds3-like DivIVA PF05103.8 EMC80069.1 - 4.3 7.4 8.8 5.6 7.0 0.4 2.3 1 1 1 2 2 2 0 DivIVA protein DUF1242 PF06842.7 EMC80070.1 - 1.7e-19 68.9 3.5 2.5e-19 68.4 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Pkinase PF00069.20 EMC80071.1 - 5.9e-60 202.6 0.0 1.2e-59 201.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80071.1 - 3e-33 114.9 0.0 7.9e-33 113.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EMC80071.1 - 3e-30 103.7 19.6 8.6e-16 57.4 4.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC80071.1 - 5.9e-09 36.3 0.8 1.2e-08 35.3 0.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF4206 PF13901.1 EMC80071.1 - 0.0017 17.9 11.8 0.016 14.7 1.8 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4206) zf-RING-like PF08746.6 EMC80071.1 - 0.014 15.4 17.9 0.22 11.5 4.5 2.8 2 0 0 2 2 2 0 RING-like domain DZR PF12773.2 EMC80071.1 - 0.018 14.8 13.1 0.059 13.1 1.9 2.8 2 0 0 2 2 2 0 Double zinc ribbon C1_3 PF07649.7 EMC80071.1 - 0.023 14.7 14.0 0.026 14.5 2.1 3.3 2 1 0 2 2 2 0 C1-like domain Prok-RING_1 PF14446.1 EMC80071.1 - 0.095 12.4 14.1 0.16 11.7 2.2 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EMC80071.1 - 0.1 12.3 18.0 0.18 11.5 2.4 2.6 2 0 0 2 2 2 0 PHD-finger Acetyltransf_8 PF13523.1 EMC80071.1 - 0.12 12.2 0.1 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GFA PF04828.9 EMC80071.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.6 2 2 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme PHD_2 PF13831.1 EMC80071.1 - 0.29 10.4 10.0 1.8 7.9 1.2 2.8 2 0 0 2 2 2 0 PHD-finger DUF2318 PF10080.4 EMC80071.1 - 3.7 7.3 13.1 1.2 8.8 3.3 2.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-Mss51 PF13824.1 EMC80071.1 - 5.5 6.9 9.3 0.51 10.2 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 6PF2K PF01591.13 EMC80072.1 - 1.4e-102 341.4 1.4 1.8e-102 341.1 0.5 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMC80072.1 - 3e-36 124.8 0.0 5.5e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMC80072.1 - 2.4e-09 37.2 0.0 6.7e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EMC80072.1 - 0.00018 20.7 0.2 0.00035 19.8 0.1 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EMC80072.1 - 0.00031 21.5 0.6 0.0021 18.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain Prefoldin PF02996.12 EMC80072.1 - 0.00063 19.3 1.2 0.0009 18.8 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit Zeta_toxin PF06414.7 EMC80072.1 - 0.0079 15.3 0.0 0.02 13.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin His_Phos_2 PF00328.17 EMC80072.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_18 PF13238.1 EMC80072.1 - 0.051 13.8 0.2 0.39 11.0 0.0 2.4 2 1 1 3 3 3 0 AAA domain Arf PF00025.16 EMC80072.1 - 0.12 11.6 0.0 0.28 10.3 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family HSF_DNA-bind PF00447.12 EMC80073.1 - 7.9e-21 74.1 0.2 9.4e-21 73.9 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_56 PF01630.13 EMC80074.1 - 2.4e-127 424.2 0.3 2.9e-127 424.0 0.2 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.8 EMC80074.1 - 0.19 11.9 13.1 1.3 9.2 1.8 2.5 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_56 PF01630.13 EMC80075.1 - 6.7e-137 455.6 0.2 8.1e-137 455.3 0.1 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.22 EMC80075.1 - 0.014 15.3 3.1 0.2 11.6 0.1 2.6 2 0 0 2 2 2 0 EGF-like domain HTH_20 PF12840.2 EMC80075.1 - 0.016 14.9 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain EGF_2 PF07974.8 EMC80075.1 - 0.13 12.4 13.8 2.1 8.5 0.7 2.6 2 0 0 2 2 2 0 EGF-like domain TUSC2 PF15000.1 EMC80076.1 - 3.9e-31 107.3 0.0 4.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Tumour suppressor candidate 2 DUF346 PF03984.8 EMC80076.1 - 0.066 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) RA PF00788.18 EMC80077.1 - 1.7e-16 60.4 0.4 5.2e-16 58.9 0.1 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.5 EMC80077.1 - 0.091 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain Ras_bdg_2 PF14847.1 EMC80077.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras-binding domain of Byr2 zf-MYND PF01753.13 EMC80078.1 - 6.4e-10 38.7 19.8 6.4e-10 38.7 13.7 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EMC80078.1 - 0.81 9.3 8.1 1.5 8.5 5.6 1.5 1 0 0 1 1 1 0 HIT zinc finger NPR2 PF06218.6 EMC80080.1 - 3.9e-73 246.5 5.7 3.7e-56 190.6 1.4 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 EMC80080.1 - 0.083 11.4 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cytochrom_B561 PF03188.11 EMC80081.1 - 1.2e-34 119.0 11.8 1.8e-34 118.5 8.2 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4131 PF13567.1 EMC80081.1 - 0.094 12.1 16.1 0.044 13.2 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1049 PF06305.6 EMC80083.1 - 0.022 14.2 0.1 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 EMC80083.1 - 0.022 13.0 0.0 0.025 12.8 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1469 PF07332.6 EMC80083.1 - 0.087 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) CEP19 PF14933.1 EMC80083.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 CEP19-like protein Methyltransf_26 PF13659.1 EMC80084.1 - 2.2e-19 69.6 0.0 4.1e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC80084.1 - 3.9e-16 58.8 0.0 7.6e-16 57.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC80084.1 - 4.8e-14 52.8 0.0 8.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC80084.1 - 3.8e-12 46.0 0.0 6.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC80084.1 - 3.5e-08 32.9 0.0 5.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EMC80084.1 - 6.4e-08 32.1 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 EMC80084.1 - 9.1e-07 28.6 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EMC80084.1 - 1.7e-06 28.3 0.0 3.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC80084.1 - 7.7e-06 25.0 0.0 2.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 EMC80084.1 - 1.4e-05 25.5 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC80084.1 - 0.00018 21.9 0.0 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EMC80084.1 - 0.0002 22.1 0.1 0.0005 20.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC80084.1 - 0.0029 17.3 0.0 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMC80084.1 - 0.0042 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EMC80084.1 - 0.0048 16.0 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.5 EMC80084.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 EMC80084.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 EMC80084.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 EMC80084.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.1 EMC80084.1 - 0.035 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.13 EMC80084.1 - 0.035 13.5 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 DNA methylase Methyltransf_5 PF01795.14 EMC80084.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family PCMT PF01135.14 EMC80084.1 - 0.063 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 EMC80084.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF938 PF06080.7 EMC80084.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GCD14 PF08704.5 EMC80084.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SH2 PF00017.19 EMC80085.1 - 6.8e-14 51.4 0.0 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 EMC80085.1 - 5.3e-13 48.5 1.2 1.3e-12 47.3 0.9 1.7 1 0 0 1 1 1 1 SOCS box Pkinase PF00069.20 EMC80086.1 - 2e-63 213.9 0.0 3.2e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80086.1 - 8.6e-30 103.6 0.0 1.3e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC80086.1 - 7.4e-07 28.4 0.1 1.4e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC80086.1 - 0.00043 19.3 0.0 0.00072 18.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EMC80086.1 - 0.016 14.7 0.0 0.087 12.3 0.0 2.0 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EMC80086.1 - 0.047 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2132 PF09905.4 EMC80086.1 - 0.065 13.1 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) APH PF01636.18 EMC80086.1 - 0.11 12.1 0.0 0.59 9.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ded_cyto PF06920.8 EMC80087.1 - 2.8e-55 186.3 0.5 5.4e-55 185.4 0.4 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EMC80087.1 - 3.7e-53 179.8 0.0 1.1e-52 178.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Armet PF10208.4 EMC80088.1 - 1.4e-74 248.9 2.6 1.5e-74 248.7 1.8 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding CheZ PF04344.8 EMC80088.1 - 0.0031 17.2 0.0 0.0043 16.7 0.0 1.2 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ Cauli_DNA-bind PF03310.8 EMC80088.1 - 0.027 14.2 1.4 0.047 13.5 1.0 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein HeH PF12949.2 EMC80088.1 - 0.035 13.6 0.1 0.088 12.3 0.1 1.7 1 0 0 1 1 1 0 HeH/LEM domain LisH PF08513.6 EMC80089.1 - 0.014 15.1 0.1 0.15 11.8 0.0 2.6 3 0 0 3 3 3 0 LisH FAM176 PF14851.1 EMC80089.1 - 6.5 6.4 13.1 20 4.8 9.1 1.9 1 0 0 1 1 1 0 FAM176 family Sema PF01403.14 EMC80090.1 - 2.3e-110 369.1 0.0 2.3e-65 220.8 0.0 2.1 2 0 0 2 2 2 2 Sema domain I-set PF07679.11 EMC80090.1 - 2.6e-05 23.9 0.0 4.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC80090.1 - 4.6e-05 23.4 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.20 EMC80090.1 - 0.00014 21.9 9.9 0.00036 20.6 6.9 1.7 1 0 0 1 1 1 1 Plexin repeat Ig_2 PF13895.1 EMC80090.1 - 0.0066 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC80090.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain RRM_6 PF14259.1 EMC80091.1 - 1.9e-13 50.1 0.0 7.3e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EMC80091.1 - 2.1e-05 24.1 0.7 6.5e-05 22.6 0.5 1.9 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EMC80091.1 - 0.003 17.3 0.1 0.0071 16.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC80091.1 - 0.14 11.8 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mon1 PF03164.9 EMC80092.1 - 2.2e-181 602.9 0.8 2.6e-181 602.7 0.6 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Pkinase PF00069.20 EMC80093.1 - 4.4e-45 153.8 0.0 5.5e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80093.1 - 2.6e-21 75.8 0.0 3.2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC80093.1 - 0.0016 17.4 0.1 0.026 13.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EMC80093.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Reo_sigmaC PF04582.7 EMC80094.1 - 0.0039 16.4 3.0 0.21 10.7 0.2 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Laminin_II PF06009.7 EMC80094.1 - 0.0052 16.5 6.1 0.0052 16.5 4.2 2.6 2 1 0 2 2 2 1 Laminin Domain II Cast PF10174.4 EMC80094.1 - 0.0064 14.6 2.8 0.0064 14.6 2.0 2.6 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone SlyX PF04102.7 EMC80094.1 - 0.04 14.2 2.2 0.04 14.2 1.5 3.9 1 1 2 4 4 4 0 SlyX WEMBL PF05701.6 EMC80094.1 - 0.073 11.5 34.0 0.047 12.1 8.7 2.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.6 EMC80094.1 - 0.28 9.7 33.2 0.14 10.8 10.5 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Filament PF00038.16 EMC80094.1 - 0.51 9.7 29.1 1.1 8.6 20.2 1.4 1 1 0 1 1 1 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 EMC80094.1 - 0.51 10.1 38.8 1.2 8.9 9.0 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FimP PF09766.4 EMC80094.1 - 0.59 9.1 22.2 0.032 13.2 4.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein DUF1664 PF07889.7 EMC80094.1 - 0.82 9.4 22.4 0.38 10.5 5.2 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) KSR1-SAM PF13543.1 EMC80094.1 - 0.99 9.1 13.8 0.046 13.5 1.8 2.9 1 1 1 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 Tropomyosin_1 PF12718.2 EMC80094.1 - 1 9.1 33.9 0.074 12.9 8.7 2.9 2 1 0 2 2 2 0 Tropomyosin like Uds1 PF15456.1 EMC80094.1 - 1.3 9.0 23.9 2.6 8.0 0.2 3.5 1 1 2 3 3 3 0 Up-regulated During Septation APG6 PF04111.7 EMC80094.1 - 1.4 7.8 31.5 3.4 6.6 10.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 UPF0449 PF15136.1 EMC80094.1 - 1.9 8.7 11.3 0.073 13.2 2.4 2.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 AAA_13 PF13166.1 EMC80094.1 - 2.3 6.5 24.9 10 4.4 17.3 1.8 1 1 0 1 1 1 0 AAA domain KxDL PF10241.4 EMC80094.1 - 2.4 8.1 11.8 0.15 12.0 3.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein GAS PF13851.1 EMC80094.1 - 2.8 7.0 35.6 1.9 7.6 10.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.6 EMC80094.1 - 3.5 6.9 17.0 2.1 7.6 4.2 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Phage_GP20 PF06810.6 EMC80094.1 - 3.9 6.8 30.5 0.33 10.3 6.9 3.7 2 2 2 4 4 4 0 Phage minor structural protein GP20 Na_trans_assoc PF06512.8 EMC80094.1 - 4.1 7.2 11.8 16 5.3 8.2 1.9 1 1 0 1 1 1 0 Sodium ion transport-associated Myosin_head PF00063.16 EMC80096.1 - 7.4e-267 886.9 2.5 7.4e-267 886.9 1.7 2.2 3 0 0 3 3 3 1 Myosin head (motor domain) DIL PF01843.14 EMC80096.1 - 1.1e-38 131.3 2.3 1.1e-38 131.3 1.6 3.8 4 0 0 4 4 4 1 DIL domain IQ PF00612.22 EMC80096.1 - 6.9e-25 84.2 42.9 0.00011 21.5 2.5 6.8 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 EMC80096.1 - 0.0022 18.1 0.0 0.021 14.9 0.0 2.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC80096.1 - 0.5 10.3 0.0 0.5 10.3 0.0 4.1 4 0 0 4 4 4 0 AAA ATPase domain Endosulfine PF04667.12 EMC80097.1 - 3.2e-15 55.8 1.1 3.6e-15 55.6 0.8 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4210 PF13915.1 EMC80098.1 - 4e-20 71.8 0.1 1.1e-19 70.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EMC80098.1 - 1.2e-19 69.8 0.4 2.9e-19 68.6 0.3 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis CUT PF02376.10 EMC80099.1 - 7.9e-32 108.9 0.4 1.4e-31 108.1 0.3 1.3 1 0 0 1 1 1 1 CUT domain Homeobox PF00046.24 EMC80099.1 - 2.2e-10 39.9 0.6 4.2e-10 39.1 0.4 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC80099.1 - 0.001 18.7 0.0 0.003 17.2 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain C2 PF00168.25 EMC80100.1 - 2.2e-05 24.1 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 EMC80101.1 - 3.4e-55 185.5 2.9 5.2e-55 185.0 0.5 2.6 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.12 EMC80101.1 - 1.1e-39 134.8 0.4 1.1e-39 134.8 0.3 3.3 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) C2 PF00168.25 EMC80101.1 - 3e-38 129.5 3.2 6.8e-25 86.7 0.3 3.1 2 0 0 2 2 2 2 C2 domain C1_1 PF00130.17 EMC80101.1 - 1.8e-10 40.4 6.4 3.7e-10 39.3 4.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FlaC_arch PF05377.6 EMC80101.1 - 0.047 13.5 3.7 0.07 13.0 0.9 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Med9 PF07544.8 EMC80101.1 - 0.052 13.2 2.9 0.072 12.8 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ribosomal_L24e PF01246.15 EMC80102.1 - 7.3e-13 48.1 5.7 7.3e-13 48.1 4.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DDE_Tnp_1_4 PF13701.1 EMC80102.1 - 0.022 12.9 2.1 0.024 12.8 1.5 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Ras PF00071.17 EMC80103.1 - 1.6e-57 193.4 0.0 1.9e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80103.1 - 1.7e-16 60.7 0.0 2.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC80103.1 - 8.6e-12 44.6 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC80103.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC80103.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC80103.1 - 0.019 14.0 0.0 0.35 9.9 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EMC80103.1 - 0.025 13.8 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EMC80103.1 - 0.045 13.4 0.1 5.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 EMC80103.1 - 0.088 12.9 0.0 0.25 11.4 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EMC80103.1 - 0.12 11.9 0.2 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EMC80103.1 - 0.13 11.4 0.0 0.43 9.7 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EMC80103.1 - 0.13 13.0 0.1 1.8 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3243 PF11588.3 EMC80104.1 - 0.0085 16.0 3.0 0.024 14.6 0.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3243) DUF1664 PF07889.7 EMC80104.1 - 0.0086 15.8 21.9 0.37 10.6 1.1 3.8 2 1 1 3 3 3 3 Protein of unknown function (DUF1664) FUSC PF04632.7 EMC80104.1 - 0.15 10.4 4.4 0.23 9.8 3.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family JSRP PF15312.1 EMC80104.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Junctional sarcoplasmic reticulum protein PHD PF00628.24 EMC80106.1 - 6.3e-07 28.9 5.9 1.1e-06 28.2 4.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EMC80106.1 - 0.0076 15.9 2.8 0.0076 15.9 1.9 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DUF1498 PF07385.7 EMC80106.1 - 0.17 11.0 0.4 0.27 10.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) zf-RING_2 PF13639.1 EMC80106.1 - 0.17 11.7 4.5 0.31 10.9 3.1 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 EMC80106.1 - 1.3 9.0 5.1 0.86 9.6 1.9 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain PALP PF00291.20 EMC80107.1 - 1.2e-55 188.9 0.2 1.4e-55 188.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_6 PF13740.1 EMC80107.1 - 0.00096 18.8 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain DUF4499 PF14934.1 EMC80108.1 - 1.6e-32 111.2 6.5 1.9e-32 111.0 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF663 PF04950.7 EMC80109.1 - 6.4e-89 297.8 0.0 6.4e-89 297.8 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMC80109.1 - 3.7e-28 96.8 0.0 1.3e-27 95.1 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EMC80109.1 - 1.8e-07 30.7 0.1 0.00012 21.6 0.0 3.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 EMC80109.1 - 4.6e-05 23.1 1.4 8.7e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EMC80109.1 - 0.00041 20.3 0.3 0.0023 17.8 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC80109.1 - 0.0042 17.0 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EMC80109.1 - 0.0099 16.0 0.1 0.029 14.5 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EMC80109.1 - 0.013 15.9 1.2 0.043 14.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Gly_acyl_tr_C PF08444.5 EMC80109.1 - 0.036 14.0 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region AAA_22 PF13401.1 EMC80109.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMC80109.1 - 0.041 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC80109.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ArgK PF03308.11 EMC80109.1 - 0.29 9.8 3.0 0.91 8.2 0.0 2.5 2 0 0 2 2 2 0 ArgK protein Pkinase_Tyr PF07714.12 EMC80110.1 - 1.3e-103 345.6 0.0 1.8e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC80110.1 - 1e-47 162.4 0.0 1.9e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cadherin PF00028.12 EMC80110.1 - 7.7e-19 67.7 0.3 5.5e-09 36.1 0.0 5.0 4 1 0 4 4 4 3 Cadherin domain Cadherin_2 PF08266.7 EMC80110.1 - 0.0096 15.4 0.3 2 8.0 0.0 2.9 3 0 0 3 3 3 2 Cadherin-like RIO1 PF01163.17 EMC80110.1 - 0.027 13.8 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family CHGN PF05679.11 EMC80111.1 - 2.4e-60 204.6 0.0 3.3e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 EMC80111.1 - 3.4e-09 36.0 0.2 7.4e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC80111.1 - 8.9e-07 28.2 0.0 1.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 KfrA_N PF11740.3 EMC80111.1 - 0.0042 17.5 0.2 0.0077 16.6 0.2 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term FadA PF09403.5 EMC80111.1 - 0.013 15.4 0.9 0.03 14.3 0.6 1.5 1 0 0 1 1 1 0 Adhesion protein FadA DUF4525 PF15027.1 EMC80111.1 - 0.069 12.6 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Allexi_40kDa PF05549.6 EMC80111.1 - 0.13 11.5 0.8 0.25 10.6 0.5 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Fib_alpha PF08702.5 EMC80111.1 - 0.16 12.1 4.1 0.36 10.9 2.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Striatin PF08232.7 EMC80111.1 - 0.16 12.2 4.7 0.31 11.3 3.2 1.4 1 0 0 1 1 1 0 Striatin family Prefoldin PF02996.12 EMC80111.1 - 0.35 10.5 4.9 0.29 10.8 1.9 1.9 2 0 0 2 2 2 0 Prefoldin subunit DUF342 PF03961.8 EMC80111.1 - 0.37 9.1 2.7 0.57 8.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EMC80111.1 - 4.5 6.9 8.3 0.79 9.4 2.7 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EMC80111.1 - 5.3 6.5 10.9 10 5.6 7.6 1.4 1 1 0 1 1 1 0 IncA protein RasGEF PF00617.14 EMC80112.1 - 1.5e-46 158.4 2.1 1.5e-46 158.4 1.4 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EMC80112.1 - 2e-20 72.8 0.2 9.5e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif VHS PF00790.14 EMC80112.1 - 0.071 12.7 1.7 1 8.9 0.1 2.4 1 1 1 2 2 2 0 VHS domain Taeniidae_ag PF05596.6 EMC80112.1 - 0.072 12.9 1.3 6.8 6.5 0.0 3.4 3 1 0 3 3 3 0 Taeniidae antigen DUF2605 PF10792.4 EMC80112.1 - 0.1 12.3 0.8 1 9.1 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2605) Lectin_C PF00059.16 EMC80113.1 - 5.3e-21 75.2 0.2 6.3e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.16 EMC80114.1 - 1.6e-16 60.8 0.5 2e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain S-AdoMet_synt_C PF02773.11 EMC80116.1 - 7.4e-78 258.9 0.3 1.2e-77 258.3 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EMC80116.1 - 3.4e-48 162.5 0.0 6.2e-48 161.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EMC80116.1 - 4.9e-43 145.4 0.1 1e-42 144.4 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Dpy-30 PF05186.8 EMC80117.1 - 9.9e-13 47.3 0.0 1.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Methyltrn_RNA_4 PF09936.4 EMC80117.1 - 0.13 11.7 1.6 0.2 11.1 1.1 1.2 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase DUF572 PF04502.8 EMC80117.1 - 0.16 11.1 15.7 0.17 11.0 10.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pilt PF15453.1 EMC80117.1 - 0.45 10.1 5.5 0.52 9.9 3.8 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions MIF4G_like_2 PF09090.6 EMC80117.1 - 0.52 9.4 7.6 0.58 9.3 5.2 1.1 1 0 0 1 1 1 0 MIF4G like Ycf1 PF05758.7 EMC80117.1 - 3.1 5.3 7.8 3.2 5.3 5.4 1.1 1 0 0 1 1 1 0 Ycf1 APG6 PF04111.7 EMC80117.1 - 3.7 6.5 15.8 4.6 6.1 10.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0444 PF15475.1 EMC80119.1 - 0.05 13.6 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Tetraspannin PF00335.15 EMC80120.1 - 6.1e-41 140.1 10.9 7.3e-41 139.8 7.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2367 PF10164.4 EMC80120.1 - 0.15 11.8 3.2 5.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Sensor PF13796.1 EMC80120.1 - 1.5 8.3 10.3 0.65 9.5 4.2 2.2 3 0 0 3 3 3 0 Putative sensor SH2 PF00017.19 EMC80121.1 - 2.2e-16 59.4 0.1 6.7e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain FYVE PF01363.16 EMC80122.1 - 4.9e-16 58.3 18.8 1.7e-15 56.6 13.1 2.0 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.14 EMC80122.1 - 9.6e-09 35.0 0.1 9.6e-09 35.0 0.1 4.7 4 3 0 4 4 4 1 RUN domain GOLD_2 PF13897.1 EMC80122.1 - 1.9e-05 24.9 0.0 1.9e-05 24.9 0.0 6.6 4 3 3 8 8 8 1 Golgi-dynamics membrane-trafficking Tropomyosin_1 PF12718.2 EMC80122.1 - 0.00069 19.4 32.1 0.00069 19.4 22.2 11.6 2 1 11 13 13 13 3 Tropomyosin like Myosin_tail_1 PF01576.14 EMC80122.1 - 0.045 11.4 237.9 0.0098 13.6 99.2 4.6 1 1 3 4 4 4 0 Myosin tail 7tm_1 PF00001.16 EMC80123.1 - 8.3e-44 149.6 22.1 1.2e-43 149.1 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC80123.1 - 4.5 7.0 25.8 0.02 14.6 8.3 3.1 1 1 2 3 3 3 0 Olfactory receptor PLAC8 PF04749.12 EMC80123.1 - 6.5 7.3 10.4 43 4.7 3.0 3.3 2 1 0 2 2 2 0 PLAC8 family Macoilin PF09726.4 EMC80124.1 - 0.0009 17.6 18.5 0.0018 16.6 12.8 1.5 1 1 0 1 1 1 1 Transmembrane protein Lzipper-MIP1 PF14389.1 EMC80124.1 - 3.3 7.8 18.3 1.3e+02 2.7 12.8 2.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 PEARLI-4 PF05278.7 EMC80125.1 - 0.013 14.9 5.2 1.3 8.3 0.4 2.4 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) ATG16 PF08614.6 EMC80125.1 - 0.049 13.4 27.0 0.44 10.3 3.6 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TSC22 PF01166.13 EMC80125.1 - 0.064 13.2 5.8 2.6 8.0 0.3 3.6 3 1 0 3 3 3 0 TSC-22/dip/bun family Spc7 PF08317.6 EMC80125.1 - 0.2 10.2 23.0 0.31 9.6 4.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Lebercilin PF15619.1 EMC80125.1 - 1.2 8.4 26.4 0.18 11.2 15.6 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Reo_sigmaC PF04582.7 EMC80125.1 - 1.4 8.0 8.6 2.9 6.9 2.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2422 PF10337.4 EMC80125.1 - 1.7 7.3 9.5 3 6.5 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) ADIP PF11559.3 EMC80125.1 - 1.7 8.5 27.8 1.4 8.7 6.4 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.6 EMC80125.1 - 1.8 7.8 18.5 0.14 11.5 2.0 2.7 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF3552 PF12072.3 EMC80125.1 - 6.5 5.9 14.3 1.8 7.7 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CENP-F_leu_zip PF10473.4 EMC80125.1 - 6.5 6.6 30.2 1.1 9.1 6.3 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EMC80125.1 - 7.6 6.3 9.3 21 4.9 1.8 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EMC80125.1 - 8.4 6.2 26.4 0.5 10.2 1.4 5.1 1 1 5 6 6 6 0 TATA element modulatory factor 1 DNA binding Zfx_Zfy_act PF04704.8 EMC80126.1 - 1.5e-128 428.2 36.8 5.8e-128 426.3 22.4 2.7 2 1 0 2 2 2 1 Zfx / Zfy transcription activation region zf-H2C2_2 PF13465.1 EMC80126.1 - 3.6e-40 134.2 120.7 4.9e-07 29.7 3.2 12.9 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 EMC80126.1 - 1.4e-38 128.9 117.3 5.1e-06 26.5 1.9 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80126.1 - 1e-31 106.9 101.7 0.00023 21.2 1.2 12.4 12 0 0 12 12 12 10 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC80126.1 - 8.4e-20 69.7 100.9 0.00097 19.2 3.1 12.1 12 0 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EMC80126.1 - 1e-16 60.5 76.5 9e-05 22.4 0.1 11.5 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC80126.1 - 0.099 12.8 74.7 0.13 12.4 0.1 10.8 11 0 0 11 11 11 0 Zinc-finger of C2H2 type Myotub-related PF06602.9 EMC80128.1 - 1.7e-146 487.5 0.1 2.5e-146 487.0 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 EMC80128.1 - 2.4e-12 46.2 0.0 5.5e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 EMC80128.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC80128.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC80128.1 - 0.0074 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family 3-PAP PF12578.3 EMC80128.1 - 0.014 15.2 0.7 0.039 13.7 0.3 1.8 1 1 0 1 1 1 0 Myotubularin-associated protein Myotub-related PF06602.9 EMC80129.1 - 2.3e-146 487.0 0.0 3e-146 486.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 EMC80129.1 - 6.3e-08 32.0 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 EMC80129.1 - 0.00016 21.1 0.0 0.00037 19.9 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC80129.1 - 0.00035 20.8 0.0 0.00071 19.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EMC80129.1 - 0.00059 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4441 PF14536.1 EMC80129.1 - 0.056 13.4 0.8 0.14 12.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) CD99L2 PF12301.3 EMC80130.1 - 1.6e-40 138.5 2.5 2e-40 138.2 1.7 1.1 1 0 0 1 1 1 1 CD99 antigen like protein 2 HMG_box_2 PF09011.5 EMC80131.1 - 1.6e-50 169.3 11.0 6.4e-30 103.3 5.4 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EMC80131.1 - 7.9e-44 147.7 10.2 1.4e-27 95.6 0.1 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.1 EMC80131.1 - 6.2e-05 22.7 11.0 0.018 14.8 1.9 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 CHDNT PF08073.7 EMC80131.1 - 0.062 13.0 0.0 8.1 6.2 0.0 2.6 2 0 0 2 2 2 0 CHDNT (NUC034) domain Nucleoplasmin PF03066.10 EMC80131.1 - 0.38 10.2 11.1 0.68 9.4 7.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin YABBY PF04690.8 EMC80131.1 - 1.5 9.0 5.8 0.63 10.2 0.1 2.3 2 1 1 3 3 3 0 YABBY protein EBV-NA3 PF05009.7 EMC80131.1 - 7.2 5.7 6.6 12 5.1 4.5 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribosomal_60s PF00428.14 EMC80131.1 - 8.6 6.8 25.3 0.16 12.3 12.5 1.9 2 1 0 2 2 2 0 60s Acidic ribosomal protein 7tm_1 PF00001.16 EMC80132.1 - 2.3e-43 148.2 26.8 2.9e-43 147.8 18.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC80132.1 - 2.9e-07 29.8 25.0 4.7e-07 29.1 17.3 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3980 PF13140.1 EMC80132.1 - 1.1 9.6 16.2 4.7 7.5 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Git3 PF11710.3 EMC80132.1 - 1.3 8.5 23.8 1 8.8 10.6 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 VMA21 PF09446.5 EMC80133.1 - 2.2e-09 37.0 0.5 2.7e-09 36.8 0.4 1.1 1 0 0 1 1 1 1 VMA21-like domain RVT_1 PF00078.22 EMC80134.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.12 EMC80135.1 - 1.5e-56 188.6 0.9 7.6e-20 70.9 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.7 EMC80135.1 - 5.1e-35 118.9 0.2 2.4e-32 110.3 0.1 4.3 4 1 1 5 5 5 1 Cadherin-like zinc-ribbons_6 PF07191.7 EMC80136.1 - 0.098 12.4 9.3 21 4.9 0.2 4.0 3 1 1 4 4 4 0 zinc-ribbons SERTA PF06031.8 EMC80137.1 - 8.6e-17 60.1 0.2 1.5e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 SERTA motif C2 PF00168.25 EMC80138.1 - 7.8e-19 67.3 0.0 2.1e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain Bcr-Abl_Oligo PF09036.5 EMC80138.1 - 0.061 13.2 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF1253 PF06862.7 EMC80139.1 - 1.3e-165 551.1 3.7 1.7e-165 550.7 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Glyco_hydro_14 PF01373.12 EMC80139.1 - 0.064 11.9 0.4 0.45 9.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 14 Daxx PF03344.10 EMC80139.1 - 1.1 7.6 28.5 1.5 7.1 19.8 1.1 1 0 0 1 1 1 0 Daxx Family Ribosomal_S10 PF00338.17 EMC80140.1 - 6e-24 83.7 0.2 8e-24 83.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ClpS PF02617.12 EMC80141.1 - 1.1e-20 73.0 0.3 3.2e-20 71.6 0.2 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.15 EMC80141.1 - 2e-19 69.0 7.9 2e-19 69.0 5.5 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Tetraspannin PF00335.15 EMC80142.1 - 1.9e-45 154.8 9.9 4.5e-45 153.6 6.9 1.5 1 1 0 1 1 1 1 Tetraspanin family TBCC PF07986.7 EMC80143.1 - 1.5e-26 92.1 0.1 1.7e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor C GLTSCR1 PF15249.1 EMC80144.1 - 4.3e-32 110.4 1.5 1.2e-31 109.0 1.0 1.8 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region PIP49_C PF12260.3 EMC80145.1 - 1.4e-11 44.2 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 SopE_GEF PF07487.8 EMC80145.1 - 0.088 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 SopE GEF domain RhoGAP PF00620.22 EMC80146.1 - 7.9e-48 161.9 0.0 2e-47 160.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain DUF1679 PF07914.6 EMC80146.1 - 0.084 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ras PF00071.17 EMC80147.1 - 1.6e-53 180.4 0.0 1.8e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80147.1 - 7.1e-16 58.7 0.0 1.9e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC80147.1 - 2.6e-08 33.2 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC80147.1 - 0.002 17.5 0.1 0.027 13.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC80147.1 - 0.02 14.8 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ORC3_N PF07034.6 EMC80147.1 - 0.092 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus wnt PF00110.14 EMC80148.1 - 3e-127 424.0 25.1 3.4e-127 423.9 17.4 1.0 1 0 0 1 1 1 1 wnt family MEF2_binding PF09047.5 EMC80148.1 - 0.18 11.4 1.0 0.43 10.2 0.7 1.5 1 0 0 1 1 1 0 MEF2 binding zf-H2C2_2 PF13465.1 EMC80149.1 - 1.7e-42 141.6 96.7 8.4e-08 32.1 0.3 14.4 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.21 EMC80149.1 - 3.3e-31 105.7 97.8 1.2e-05 25.2 0.4 14.5 14 0 0 14 14 14 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80149.1 - 2.6e-20 71.2 101.5 0.0031 17.7 0.3 14.5 14 0 0 14 14 14 11 C2H2-type zinc finger BTB PF00651.26 EMC80149.1 - 2.1e-19 69.5 0.2 5.9e-19 68.0 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.1 EMC80149.1 - 3.6e-10 39.3 65.8 0.16 11.8 0.1 13.5 13 0 0 13 13 13 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC80149.1 - 4e-10 39.5 57.3 0.58 10.3 0.1 13.2 14 0 0 14 14 14 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC80149.1 - 0.87 9.8 59.4 1.4 9.2 0.2 11.7 12 0 0 12 12 12 0 Zinc-finger of C2H2 type Pkinase_Tyr PF07714.12 EMC80150.1 - 6.4e-92 307.2 0.0 8.7e-92 306.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC80150.1 - 4.4e-74 248.1 0.1 6.9e-74 247.4 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC80150.1 - 4e-45 153.9 0.0 5.9e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC80150.1 - 1.1e-32 111.9 0.1 1.6e-16 60.2 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC80150.1 - 6.8e-26 90.4 0.0 1.3e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 EMC80150.1 - 2.1e-20 72.6 0.1 3.8e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC80150.1 - 2.1e-16 59.5 0.0 4.7e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC80150.1 - 0.00038 19.9 2.2 0.00038 19.9 1.5 2.4 2 0 0 2 2 2 1 GCC2 and GCC3 Interfer-bind PF09294.5 EMC80150.1 - 0.0013 18.7 0.1 0.012 15.6 0.1 2.4 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 EMC80150.1 - 0.0016 18.2 0.0 0.43 10.4 0.1 2.3 2 0 0 2 2 2 1 SusE outer membrane protein Kdo PF06293.9 EMC80150.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3300 PF11737.3 EMC80150.1 - 0.52 9.5 5.7 1.2 8.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3300) C1q PF00386.16 EMC80151.1 - 1.7e-34 118.5 0.1 2.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC80151.1 - 2.5e-12 46.1 31.6 2.2e-08 33.5 12.1 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNF PF00229.13 EMC80151.1 - 0.00072 19.1 0.5 0.02 14.4 0.4 2.1 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 EMC80152.1 - 1.2e-37 128.6 0.3 1.6e-37 128.3 0.2 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC80152.1 - 1e-14 53.7 44.0 1.1e-08 34.4 12.9 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNF PF00229.13 EMC80152.1 - 5.4e-05 22.7 1.1 0.00039 19.9 0.8 2.0 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Cytadhesin_P30 PF07271.6 EMC80152.1 - 0.39 9.9 10.2 0.51 9.5 7.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 PT PF04886.7 EMC80153.1 - 0.0011 18.2 19.3 0.13 11.5 3.1 4.1 1 1 1 2 2 2 2 PT repeat Pkinase_Tyr PF07714.12 EMC80154.1 - 3.7e-94 314.6 0.0 5.5e-94 314.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC80154.1 - 2.3e-78 262.0 0.1 3.8e-78 261.3 0.1 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC80154.1 - 4.1e-46 157.2 0.0 6.3e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC80154.1 - 1.7e-37 127.4 3.3 1.7e-17 63.2 0.6 3.3 4 0 0 4 4 4 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC80154.1 - 8.9e-29 99.7 0.0 1.6e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 EMC80154.1 - 1.1e-23 83.2 0.2 2.6e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC80154.1 - 7e-20 70.6 0.0 1.4e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC80154.1 - 3.3e-07 29.7 6.2 3.3e-07 29.7 4.3 2.8 2 2 1 3 3 3 1 GCC2 and GCC3 Interfer-bind PF09294.5 EMC80154.1 - 0.0048 16.9 0.0 0.51 10.3 0.0 3.0 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III cEGF PF12662.2 EMC80154.1 - 0.32 10.6 8.7 1.1 8.9 1.1 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like Beta-lactamase PF00144.19 EMC80155.1 - 3.7e-37 128.0 0.0 5.7e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Guanylin PF02058.10 EMC80156.1 - 1.8e-27 95.1 1.2 2e-27 95.0 0.9 1.0 1 0 0 1 1 1 1 Guanylin precursor Enterotoxin_ST PF02048.11 EMC80156.1 - 0.028 14.6 5.6 0.061 13.5 3.9 1.6 1 0 0 1 1 1 0 Heat-stable enterotoxin ST ADP_ribosyl_GH PF03747.9 EMC80157.1 - 1.4e-37 130.0 3.7 1.7e-37 129.7 2.6 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Leu_zip PF15294.1 EMC80158.1 - 3.4e-118 393.7 31.0 3.9e-118 393.6 21.5 1.0 1 0 0 1 1 1 1 Leucine zipper Filament PF00038.16 EMC80158.1 - 0.00013 21.5 8.2 0.00013 21.5 5.7 2.4 1 1 1 2 2 2 2 Intermediate filament protein IL3 PF02059.10 EMC80158.1 - 0.29 11.1 9.3 0.18 11.7 1.0 2.9 1 1 0 2 2 2 0 Interleukin-3 HisKA_3 PF07730.8 EMC80158.1 - 1.1 9.6 4.7 8 6.8 0.2 3.0 2 1 0 2 2 2 0 Histidine kinase DUF2018 PF09442.5 EMC80158.1 - 4.4 7.9 6.9 3.6 8.2 0.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF2018) DUF1843 PF08898.5 EMC80158.1 - 9.3 6.3 7.3 1.2 9.2 0.2 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) SNF PF00209.13 EMC80159.1 - 4e-63 213.6 4.6 4.4e-63 213.5 3.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Nucleoside_tran PF01733.13 EMC80159.1 - 0.58 9.2 8.0 0.044 12.9 0.6 2.3 3 0 0 3 3 3 0 Nucleoside transporter Cation_ATPase_C PF00689.16 EMC80159.1 - 1.4 8.4 6.3 0.16 11.4 1.3 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus LSM PF01423.17 EMC80160.1 - 1.1e-18 66.4 0.7 1.8e-18 65.8 0.5 1.3 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EMC80160.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) LRR_1 PF00560.28 EMC80160.1 - 0.081 13.0 0.1 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Leucine Rich Repeat SM-ATX PF14438.1 EMC80160.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 EMC80160.1 - 1.1 7.6 10.1 0.18 10.2 4.4 1.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Syja_N PF02383.13 EMC80161.1 - 6.1e-16 58.0 0.0 9.8e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Syja_N PF02383.13 EMC80162.1 - 4.1e-19 68.5 0.1 5e-19 68.2 0.1 1.0 1 0 0 1 1 1 1 SacI homology domain LIM PF00412.17 EMC80163.1 - 5.8e-31 106.3 34.5 9.5e-12 44.8 4.2 3.3 3 0 0 3 3 3 3 LIM domain tRNA-synt_1 PF00133.17 EMC80165.1 - 4.4e-50 170.3 2.6 3.5e-23 81.4 4.8 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMC80165.1 - 2.2e-32 112.1 0.0 3.5e-21 75.3 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMC80165.1 - 1.4e-11 44.3 0.3 3.2e-11 43.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 EMC80165.1 - 1.9e-10 40.3 0.0 3.3e-05 23.2 0.0 2.5 1 1 0 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EMC80165.1 - 0.00081 18.6 0.0 0.22 10.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EMC80165.1 - 0.0026 16.6 0.0 0.0096 14.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 EMC80165.1 - 0.0071 15.0 0.0 0.32 9.6 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (K) fn3 PF00041.16 EMC80166.1 - 0.01 15.9 0.6 0.033 14.3 0.4 1.7 1 1 0 1 1 1 0 Fibronectin type III domain Ribosomal_S9 PF00380.14 EMC80167.1 - 3.9e-36 123.9 0.3 4.4e-36 123.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EMC80167.1 - 0.012 13.0 0.0 0.014 12.9 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Ank PF00023.25 EMC80168.1 - 2.3e-31 105.9 1.4 8.2e-08 31.6 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EMC80168.1 - 6.5e-31 106.5 0.4 3.2e-14 53.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC80168.1 - 2.6e-29 101.0 0.9 1.1e-12 48.1 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC80168.1 - 1e-26 92.3 4.3 9.4e-12 44.7 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80168.1 - 3.1e-21 73.3 1.5 0.00038 20.4 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Yae1_N PF09811.4 EMC80170.1 - 2.7e-17 61.9 55.9 1.5e+04 -17.0 38.7 5.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ion_trans_N PF08412.5 EMC80171.1 - 7.9e-45 150.0 0.1 7.9e-45 150.0 0.1 2.1 2 0 0 2 2 2 1 Ion transport protein N-terminal cNMP_binding PF00027.24 EMC80171.1 - 5.7e-21 74.1 0.0 1.2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 EMC80171.1 - 3.3e-19 68.9 10.6 6.6e-19 67.9 7.3 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EMC80171.1 - 0.0024 17.5 0.2 0.0065 16.1 0.1 1.8 1 0 0 1 1 1 1 Ion channel Neogenin_C PF06583.7 EMC80172.1 - 5.7e-119 397.4 23.1 8.9e-119 396.7 16.0 1.3 1 0 0 1 1 1 1 Neogenin C-terminus fn3 PF00041.16 EMC80172.1 - 1.8e-84 277.9 28.0 4.5e-18 65.1 0.0 6.4 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.11 EMC80172.1 - 2.3e-55 184.4 0.0 2.4e-16 59.3 0.0 6.6 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC80172.1 - 2e-33 114.3 0.0 1.6e-07 31.3 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 EMC80172.1 - 2.8e-24 85.3 2.8 1.6e-05 25.3 0.0 7.2 7 0 0 7 7 7 4 Immunoglobulin domain ig PF00047.20 EMC80172.1 - 5.8e-17 61.5 0.5 0.00071 19.6 0.0 6.2 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 EMC80172.1 - 8.3e-17 61.1 0.1 5.9e-05 22.9 0.0 6.8 6 2 0 6 6 6 3 Immunoglobulin V-set domain Interfer-bind PF09294.5 EMC80172.1 - 7.6e-15 54.8 0.1 0.041 13.9 0.0 5.9 6 0 0 6 6 6 4 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 EMC80172.1 - 1.2e-07 31.4 1.3 0.012 15.2 0.0 5.0 4 1 1 5 5 5 2 Tissue factor C2-set_2 PF08205.7 EMC80172.1 - 1.3e-07 31.4 0.0 0.057 13.3 0.0 3.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.1 EMC80172.1 - 4.7e-05 23.6 0.8 9.9e-05 22.6 0.5 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EMC80172.1 - 0.00011 20.6 0.0 0.19 9.9 0.0 4.0 2 1 2 4 4 4 1 Alphaherpesvirus glycoprotein E Ly49 PF08391.5 EMC80172.1 - 0.049 13.7 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region TMEM154 PF15102.1 EMC80172.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.1 EMC80172.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.0 3 0 0 3 3 2 0 Wnt and FGF inhibitory regulator DUF2659 PF10858.3 EMC80172.1 - 0.52 9.6 0.3 0.91 8.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) ADP_PFK_GK PF04587.10 EMC80173.1 - 6e-116 387.2 0.0 6.9e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region TPR_11 PF13414.1 EMC80174.1 - 7.8e-47 156.8 16.7 2.3e-12 46.3 2.4 6.0 4 2 2 6 6 6 5 TPR repeat TPR_2 PF07719.12 EMC80174.1 - 1e-40 134.3 19.4 3.4e-06 26.5 0.2 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMC80174.1 - 4.3e-39 130.5 19.4 6e-06 25.6 0.2 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMC80174.1 - 1.9e-31 108.0 2.1 0.00015 22.3 0.0 6.8 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 EMC80174.1 - 2.9e-31 104.8 16.7 6.5e-05 22.4 0.0 9.0 7 1 2 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMC80174.1 - 1.7e-26 92.3 11.4 3.4e-08 33.6 0.2 6.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMC80174.1 - 2.1e-26 91.6 23.5 4.8e-08 32.8 0.5 6.9 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EMC80174.1 - 1.1e-23 81.3 16.4 3.8e-05 23.5 0.0 9.1 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC80174.1 - 5.3e-22 76.3 0.8 0.00055 20.3 0.0 7.8 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMC80174.1 - 2.1e-17 62.7 0.1 0.00029 20.6 0.0 5.8 1 1 5 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EMC80174.1 - 2.6e-17 62.7 26.0 5.5e-06 26.4 1.0 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMC80174.1 - 1.1e-14 52.9 10.6 0.0011 18.6 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC80174.1 - 3.6e-10 39.6 11.8 0.36 11.4 0.0 9.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.1 EMC80174.1 - 1.8e-08 33.7 9.2 0.0057 15.7 0.7 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 EMC80174.1 - 9.8e-08 32.0 3.2 0.005 16.9 0.0 4.6 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC80174.1 - 1.2e-07 31.4 12.8 0.64 10.0 0.1 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat NARP1 PF12569.3 EMC80174.1 - 1.7e-05 23.8 7.5 0.0058 15.4 0.1 3.8 2 2 2 4 4 4 1 NMDA receptor-regulated protein 1 ChAPs PF09295.5 EMC80174.1 - 5.4e-05 22.1 0.8 0.0033 16.2 0.1 2.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.9 EMC80174.1 - 0.00094 18.4 5.9 0.51 9.4 0.5 3.4 2 1 1 3 3 3 1 Coatomer epsilon subunit Rapsyn_N PF10579.4 EMC80174.1 - 0.02 14.6 0.3 0.41 10.4 0.0 3.2 3 0 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region MIT PF04212.13 EMC80174.1 - 0.024 14.5 9.1 2.4 8.0 0.1 5.6 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 EMC80174.1 - 0.078 12.9 7.2 4 7.3 0.1 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 EMC80174.1 - 0.14 12.4 4.0 4.3 7.6 0.0 4.0 3 2 3 6 6 4 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EMC80174.1 - 2.8 7.9 8.7 5.4 6.9 0.0 4.4 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat IBR PF01485.16 EMC80175.1 - 5.4e-18 64.6 43.5 2.1e-14 53.1 6.9 4.9 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EMC80175.1 - 1.5e-06 28.0 6.4 1.5e-06 28.0 4.5 4.8 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC80175.1 - 1.2e-05 25.0 4.2 1.2e-05 25.0 2.9 4.3 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EMC80175.1 - 0.00031 20.3 3.8 0.00031 20.3 2.6 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC80175.1 - 0.00069 19.2 5.9 0.00069 19.2 4.1 4.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC80175.1 - 0.0024 17.7 5.2 0.0024 17.7 3.6 4.6 4 1 1 5 5 5 2 zinc finger of C3HC4-type, RING POTRA_2 PF08479.6 EMC80175.1 - 0.13 11.9 0.2 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type DUF3287 PF11690.3 EMC80175.1 - 0.22 11.5 6.6 0.55 10.3 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) zf-LSD1 PF06943.7 EMC80175.1 - 1 9.0 5.2 8.4 6.1 1.0 3.4 2 0 0 2 2 2 0 LSD1 zinc finger Glyco_hydro_20 PF00728.17 EMC80176.1 - 3.8e-75 253.2 0.0 4.7e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EMC80176.1 - 9.3e-12 45.7 0.0 1.6e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EMC80176.1 - 3.8e-05 24.2 0.0 6.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RRM_1 PF00076.17 EMC80177.1 - 2.6e-43 145.5 0.1 9.9e-18 63.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC80177.1 - 8.9e-28 96.0 0.0 4.9e-11 42.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC80177.1 - 2.6e-19 68.8 0.2 4.4e-08 32.8 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EMC80177.1 - 0.0011 18.9 0.0 1.1 9.3 0.0 3.4 3 0 0 3 3 3 1 RNA binding domain PK PF00224.16 EMC80178.1 - 2.7e-164 545.8 3.9 3.3e-164 545.5 2.7 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 EMC80178.1 - 0.00019 20.4 0.4 0.00048 19.0 0.3 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family KH_1 PF00013.24 EMC80178.1 - 0.4 10.3 4.1 2.4 7.8 0.3 3.0 3 0 0 3 3 3 0 KH domain TRAPPC9-Trs120 PF08626.6 EMC80179.1 - 2.3e-202 674.4 0.0 8e-202 672.6 0.0 1.7 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_1 PF00515.23 EMC80179.1 - 0.24 11.0 0.6 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC80179.1 - 0.44 10.5 1.8 21 5.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FERM_M PF00373.13 EMC80180.1 - 0.005 17.0 0.1 2 8.5 0.0 2.2 2 0 0 2 2 2 2 FERM central domain RPAP3_C PF13877.1 EMC80180.1 - 0.023 14.6 1.8 1.4 8.9 0.1 2.3 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 Complex1_LYR PF05347.10 EMC80180.1 - 0.035 13.9 0.2 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) LIM PF00412.17 EMC80180.1 - 0.058 13.4 2.3 3 8.0 0.0 2.8 3 0 0 3 3 3 0 LIM domain DUF1956 PF09209.6 EMC80180.1 - 0.063 13.2 0.1 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1956) SeqA PF03925.8 EMC80180.1 - 0.078 12.6 0.1 7.7 6.1 0.0 2.2 1 1 1 2 2 2 0 SeqA protein Pkinase_Tyr PF07714.12 EMC80181.1 - 3.4e-93 311.4 0.0 5.2e-93 310.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.8 EMC80181.1 - 5.8e-65 217.0 3.5 1.3e-64 215.8 2.4 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.20 EMC80181.1 - 4.2e-47 160.4 0.0 1e-46 159.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EMC80181.1 - 5.7e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FERM_M PF00373.13 EMC80181.1 - 0.00012 22.2 0.0 0.00012 22.2 0.0 2.6 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.5 EMC80181.1 - 0.082 12.9 0.1 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain DUF4085 PF13315.1 EMC80181.1 - 0.2 11.0 6.8 0.86 8.9 0.1 3.0 3 1 0 4 4 4 0 Protein of unknown function (DUF4085) C1-set PF07654.10 EMC80182.1 - 0.00015 21.6 0.0 0.0012 18.7 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin C1-set domain V-set PF07686.12 EMC80183.1 - 1.2e-11 44.5 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Glyco_transf_29 PF00777.13 EMC80185.1 - 1.5e-63 214.4 0.0 1.8e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) 7tm_4 PF13853.1 EMC80186.1 - 1.3e-42 145.0 18.6 1.3e-42 145.0 12.9 2.2 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC80186.1 - 5.3e-29 101.1 25.1 5.3e-29 101.1 17.4 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) zf-C2H2_4 PF13894.1 EMC80187.1 - 0.0071 16.5 0.6 0.0071 16.5 0.4 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC80187.1 - 0.011 16.0 0.7 0.011 16.0 0.5 5.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type Evr1_Alr PF04777.8 EMC80188.1 - 5.5e-30 103.1 1.7 6.8e-30 102.8 1.2 1.0 1 0 0 1 1 1 1 Erv1 / Alr family SH3_9 PF14604.1 EMC80189.1 - 2e-17 62.4 0.2 1.4e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC80189.1 - 8e-14 50.7 0.8 8.8e-09 34.6 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EMC80189.1 - 3.2e-10 39.3 0.1 1.8e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EMC80189.1 - 2.6e-09 36.8 2.4 1.2e-08 34.6 1.2 2.2 2 0 0 2 2 2 1 PX domain p47_phox_C PF08944.6 EMC80189.1 - 1.5e-05 25.1 2.2 6.4e-05 23.0 1.5 2.3 1 1 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain SH3_3 PF08239.6 EMC80189.1 - 3e-05 24.1 1.4 0.03 14.4 0.0 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.8 EMC80189.1 - 0.074 12.6 0.6 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain WD40 PF00400.27 EMC80190.1 - 7.5e-81 263.4 31.1 7.9e-11 41.4 0.3 12.6 13 0 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 EMC80190.1 - 5.7e-49 165.3 1.6 9.3e-49 164.7 1.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EMC80190.1 - 2.8e-07 29.0 6.2 1.1 7.3 0.0 5.7 4 2 1 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC80190.1 - 0.0002 20.2 7.0 0.79 8.4 0.1 5.3 1 1 3 5 5 5 4 Nup133 N terminal like NDUFB10 PF10249.4 EMC80191.1 - 1.1e-52 177.5 9.0 1.2e-52 177.3 6.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Destabilase PF05497.7 EMC80191.1 - 0.15 12.1 1.7 0.16 12.0 1.1 1.4 1 1 0 1 1 1 0 Destabilase Ribosomal_L3 PF00297.17 EMC80192.1 - 1.2e-115 385.3 11.3 1.6e-115 385.0 7.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF2404 PF10296.4 EMC80193.1 - 3.3e-32 110.4 1.4 2.6e-30 104.3 0.0 3.0 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) SelR PF01641.13 EMC80195.1 - 5.8e-18 64.7 0.2 6.2e-18 64.6 0.1 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.1 EMC80195.1 - 0.0017 18.5 0.2 0.84 9.9 0.0 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.1 EMC80195.1 - 0.015 15.6 0.1 0.05 13.9 0.1 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar RRN7 PF11781.3 EMC80195.1 - 0.029 13.8 0.4 0.99 8.9 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EMC80195.1 - 0.04 13.2 0.1 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 EMC80195.1 - 0.063 12.7 2.8 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 EMC80195.1 - 0.068 12.8 1.5 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DZR PF12773.2 EMC80195.1 - 0.072 12.9 0.5 0.16 11.7 0.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon GFA PF04828.9 EMC80195.1 - 0.079 12.9 0.8 6.1 6.8 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1595 PF12760.2 EMC80195.1 - 0.084 12.6 0.8 1.5 8.7 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMC80195.1 - 0.085 12.5 3.7 0.82 9.4 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMC80195.1 - 0.098 12.2 4.0 0.82 9.3 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EMC80195.1 - 0.19 11.1 3.0 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 EMC80195.1 - 0.28 10.4 3.0 4.6 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EMC80195.1 - 0.29 10.9 0.1 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.5 EMC80195.1 - 0.52 9.8 3.8 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Mss51 PF13824.1 EMC80195.1 - 0.57 10.0 2.1 3.9 7.4 0.1 2.1 1 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.6 EMC80195.1 - 2.5 7.7 5.8 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DAGK_acc PF00609.14 EMC80196.1 - 1.4e-55 187.8 0.0 3.2e-55 186.6 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EMC80196.1 - 2.1e-30 104.8 0.0 3.7e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EMC80196.1 - 1e-20 73.1 34.9 2.5e-12 46.3 4.9 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.27 EMC80196.1 - 5e-12 44.1 0.4 6.8e-05 21.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC80196.1 - 5.1e-09 36.1 0.2 1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC80196.1 - 8.5e-09 34.5 0.0 0.00024 20.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EMC80196.1 - 8.5e-08 31.2 0.1 0.016 14.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMC80196.1 - 6.6e-06 25.6 0.2 0.018 14.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC80196.1 - 0.0024 17.8 1.0 0.0083 16.1 0.1 2.5 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region ETS_PEA3_N PF04621.8 EMC80197.1 - 2.3e-149 497.3 20.5 3e-149 496.9 14.2 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.17 EMC80197.1 - 7.3e-38 128.5 0.2 1.2e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Ets-domain Arf PF00025.16 EMC80198.1 - 6e-67 224.2 0.0 6.9e-67 224.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC80198.1 - 1.3e-17 63.6 0.0 1.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80198.1 - 1.3e-14 54.6 0.1 1.8e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EMC80198.1 - 1.8e-12 46.8 0.1 1.8e-12 46.8 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC80198.1 - 3.4e-08 32.5 0.7 1.3e-06 27.3 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 EMC80198.1 - 1.5e-06 27.7 0.1 1.9e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC80198.1 - 1.9e-06 27.8 0.1 2.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC80198.1 - 8.3e-06 25.1 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMC80198.1 - 0.0033 17.0 0.0 0.012 15.2 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.13 EMC80198.1 - 0.017 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 EMC80198.1 - 0.024 14.5 0.1 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ACT PF01842.20 EMC80198.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain Gelsolin PF00626.17 EMC80199.1 - 9.7e-19 66.8 0.3 5.1e-11 42.1 0.0 2.4 3 0 0 3 3 3 2 Gelsolin repeat DUF669 PF05037.8 EMC80199.1 - 0.11 12.3 0.3 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Gelsolin PF00626.17 EMC80200.1 - 1.8e-12 46.7 0.0 9.5e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat EGF_2 PF07974.8 EMC80201.1 - 7.5e-19 67.5 199.5 6.7e-05 22.9 4.3 13.5 12 1 1 13 13 13 11 EGF-like domain hEGF PF12661.2 EMC80201.1 - 1.5e-16 59.2 100.6 0.016 15.2 1.4 12.8 11 0 0 11 11 11 9 Human growth factor-like EGF EGF PF00008.22 EMC80201.1 - 4.4e-12 45.7 187.6 0.011 15.6 6.4 14.0 13 0 0 13 13 13 11 EGF-like domain VWD PF00094.20 EMC80201.1 - 2.2e-10 40.9 2.1 3.4e-09 37.0 0.1 3.0 2 1 0 2 2 2 1 von Willebrand factor type D domain DUF1356 PF07092.7 EMC80202.1 - 3.9e-118 392.8 3.5 4.6e-118 392.6 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) MHC2-interact PF09307.5 EMC80202.1 - 0.056 13.2 0.2 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 CLIP, MHC2 interacting DnaJ_CXXCXGXG PF00684.14 EMC80202.1 - 0.085 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 DnaJ central domain TSP_1 PF00090.14 EMC80203.1 - 2.1e-61 203.8 226.6 5.2e-13 48.8 1.2 24.0 26 1 0 26 26 26 18 Thrombospondin type 1 domain I-set PF07679.11 EMC80204.1 - 6.5e-201 650.9 13.9 2.7e-27 94.4 0.0 10.0 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC80204.1 - 1.6e-85 281.2 17.5 1.6e-11 44.1 0.0 9.6 9 0 0 9 9 9 9 Immunoglobulin domain Pkinase PF00069.20 EMC80204.1 - 4.3e-71 239.1 0.0 8.6e-71 238.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ig PF00047.20 EMC80204.1 - 2.2e-59 197.4 9.9 6.6e-07 29.3 0.1 10.0 9 0 0 9 9 9 9 Immunoglobulin domain Ig_3 PF13927.1 EMC80204.1 - 2.1e-45 153.0 13.6 3.2e-06 27.5 0.0 10.2 10 1 0 10 10 10 7 Immunoglobulin domain V-set PF07686.12 EMC80204.1 - 2.9e-45 152.8 13.9 4e-06 26.6 0.0 12.3 10 3 0 10 10 10 9 Immunoglobulin V-set domain Pkinase_Tyr PF07714.12 EMC80204.1 - 7.5e-36 123.5 0.0 1.3e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.7 EMC80204.1 - 3.2e-25 87.8 2.2 0.032 14.1 0.0 9.3 8 0 0 8 8 8 6 CD80-like C2-set immunoglobulin domain fn3 PF00041.16 EMC80204.1 - 1e-16 60.8 0.5 3.5e-16 59.0 0.4 2.0 1 0 0 1 1 1 1 Fibronectin type III domain BiPBP_C PF06832.7 EMC80204.1 - 7.7e-14 51.3 0.1 0.69 9.8 0.0 9.4 10 1 1 11 11 10 2 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.3 EMC80204.1 - 2.9e-08 33.5 0.1 1.3 8.9 0.0 6.9 7 0 0 7 7 7 2 Natural killer cell receptor 2B4 Kinase-like PF14531.1 EMC80204.1 - 0.0032 16.4 0.0 0.01 14.8 0.0 1.9 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC80204.1 - 0.015 14.4 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_gI PF01688.12 EMC80204.1 - 0.11 11.6 0.0 7.8 5.5 0.0 3.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein I PTPLA PF04387.9 EMC80205.1 - 1.1e-58 197.3 12.4 1.4e-58 196.9 8.6 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA 7TMR-DISM_7TM PF07695.6 EMC80206.1 - 2.5 7.7 17.5 9.2 5.8 12.1 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling Lectin_N PF03954.9 EMC80206.1 - 3.5 7.0 7.3 3.3 7.1 1.1 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Guanylate_cyc PF00211.15 EMC80207.1 - 4.3e-57 192.4 0.1 5.6e-57 192.0 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 EMC80207.1 - 3.1e-07 30.6 0.6 7.1e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1053) Longin PF13774.1 EMC80208.1 - 3.3e-22 77.8 0.7 5.9e-22 77.0 0.5 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sema PF01403.14 EMC80209.1 - 7.2e-137 456.4 0.2 2e-136 455.0 0.1 1.7 1 1 1 2 2 2 1 Sema domain TSP_1 PF00090.14 EMC80209.1 - 2.8e-40 136.2 96.2 1.8e-10 40.7 6.0 7.5 7 0 0 7 7 7 5 Thrombospondin type 1 domain 7TM_GPCR_Srz PF10325.4 EMC80209.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz MFS_1 PF07690.11 EMC80211.1 - 2.1e-06 26.7 27.1 2.1e-06 26.7 18.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AceK PF06315.6 EMC80211.1 - 0.18 10.0 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Cupin_8 PF13621.1 EMC80212.1 - 1.8e-36 125.9 0.0 3.1e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMC80212.1 - 6.6e-09 35.4 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EMC80212.1 - 0.00072 19.7 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pox_C7_F8A PF03287.9 EMC80212.1 - 0.17 11.5 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus C7/F8A protein EAF PF09816.4 EMC80213.1 - 1.2e-12 47.7 1.2 4.8e-12 45.7 0.0 2.6 2 2 0 2 2 2 1 RNA polymerase II transcription elongation factor Nha1_C PF08619.5 EMC80213.1 - 0.00089 18.6 10.7 0.0011 18.3 7.4 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF605 PF04652.11 EMC80213.1 - 0.05 13.0 17.3 0.054 12.8 12.0 1.1 1 0 0 1 1 1 0 Vta1 like PAN_3 PF08277.7 EMC80213.1 - 0.054 13.1 0.1 0.054 13.1 0.1 1.8 2 0 0 2 2 2 0 PAN-like domain Cwf_Cwc_15 PF04889.7 EMC80213.1 - 0.37 10.4 12.9 0.61 9.7 8.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_viral_N PF00242.12 EMC80213.1 - 0.78 8.6 9.0 0.9 8.5 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain IQ PF00612.22 EMC80214.1 - 6.7e-11 40.8 27.3 8.4e-07 28.0 0.5 5.1 5 0 0 5 5 5 4 IQ calmodulin-binding motif RhoGEF PF00621.15 EMC80216.1 - 1.5e-41 142.2 3.4 3.2e-41 141.1 2.3 1.6 1 0 0 1 1 1 1 RhoGEF domain hNIFK_binding PF12196.3 EMC80217.1 - 3.8e-15 54.9 0.5 6.6e-15 54.2 0.4 1.4 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK RRM_1 PF00076.17 EMC80217.1 - 1.6e-07 30.8 0.0 3.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC80217.1 - 6.2e-05 22.8 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC80217.1 - 8.3e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CLASP_N PF12348.3 EMC80218.1 - 4.3e-59 199.6 15.3 2.1e-39 135.2 0.4 4.7 4 1 1 5 5 5 3 CLASP N terminal HEAT PF02985.17 EMC80218.1 - 8e-20 69.0 9.5 9e-06 25.3 0.0 10.7 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 EMC80218.1 - 1.2e-13 51.1 7.1 0.0052 17.0 0.2 8.1 6 2 2 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 EMC80218.1 - 6.2e-11 42.4 4.5 0.058 13.9 0.0 6.7 6 0 0 6 6 5 2 HEAT-like repeat Sec7_N PF12783.2 EMC80218.1 - 1.6e-07 30.9 4.7 0.0033 16.8 0.0 4.9 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.2 EMC80218.1 - 1.8e-07 31.4 1.7 1.5 9.2 0.0 5.9 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EMC80218.1 - 1.2e-06 27.2 6.8 1.1 7.5 0.0 6.1 5 2 0 7 7 7 3 Adaptin N terminal region DUF2435 PF10363.4 EMC80218.1 - 3.2e-05 23.7 2.1 0.43 10.5 0.0 4.3 3 1 0 3 3 3 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 EMC80218.1 - 5.9e-05 22.9 6.5 0.0032 17.3 0.2 4.8 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 EMC80218.1 - 8e-05 22.5 3.6 0.41 10.6 0.1 5.4 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation ParcG PF10274.4 EMC80218.1 - 0.00019 21.4 0.5 0.0062 16.4 0.1 3.1 1 1 1 2 2 2 1 Parkin co-regulated protein TAN PF11640.3 EMC80218.1 - 0.00024 20.8 4.2 0.037 13.7 0.0 3.8 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair DUF2454 PF10521.4 EMC80218.1 - 0.0018 17.3 1.8 1.3 7.9 0.0 4.1 3 2 1 4 4 4 1 Protein of unknown function (DUF2454) TPR_20 PF14561.1 EMC80218.1 - 0.07 13.2 3.0 0.32 11.1 0.3 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat Nipped-B_C PF12830.2 EMC80218.1 - 0.13 11.9 2.5 9.9 5.7 0.0 3.8 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus CP2 PF04516.10 EMC80219.1 - 6.6e-72 241.3 0.1 1e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_PNT PF02198.11 EMC80219.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain TGF_beta PF00019.15 EMC80220.1 - 6.3e-36 122.8 0.5 7.6e-36 122.5 0.4 1.1 1 0 0 1 1 1 1 Transforming growth factor beta like domain BH4 PF02180.12 EMC80220.1 - 0.094 12.2 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 DUF411 PF04214.8 EMC80220.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF IN_DBD_C PF00552.16 EMC80221.1 - 1.1e-09 37.5 1.5 1.6e-09 37.0 1.0 1.3 1 0 0 1 1 1 1 Integrase DNA binding domain Ras PF00071.17 EMC80222.1 - 2.1e-54 183.2 0.1 2.6e-54 182.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80222.1 - 9.4e-18 64.8 0.2 1.8e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC80222.1 - 4.7e-10 38.9 0.0 5.7e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC80222.1 - 1.1e-05 25.0 0.0 3.8e-05 23.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC80222.1 - 1.6e-05 24.1 0.1 2.5e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC80222.1 - 0.00071 19.5 0.0 0.00097 19.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC80222.1 - 0.0022 17.2 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EMC80222.1 - 0.0048 16.0 0.1 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 EMC80222.1 - 0.011 14.8 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_25 PF13481.1 EMC80222.1 - 0.011 15.1 0.1 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMC80222.1 - 0.021 14.1 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B YTH PF04146.10 EMC80222.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 YT521-B-like domain Ser_hydrolase PF06821.8 EMC80222.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase AAA_24 PF13479.1 EMC80222.1 - 0.22 11.0 1.9 0.46 10.0 1.3 1.5 1 1 0 1 1 1 0 AAA domain FERM_C PF09380.5 EMC80224.1 - 1.1e-20 73.5 0.0 2.1e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 EMC80224.1 - 5.6e-20 71.1 0.7 2.7e-19 68.9 0.0 2.5 3 0 0 3 3 3 1 FERM N-terminal domain FERM_M PF00373.13 EMC80224.1 - 1.7e-19 70.2 0.1 4.2e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 FERM central domain FA PF08736.6 EMC80224.1 - 1.3e-14 53.6 10.5 3.5e-14 52.3 7.3 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_C PF09380.5 EMC80225.1 - 6.5e-25 87.1 0.4 1.6e-24 85.9 0.3 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 EMC80225.1 - 1.9e-24 86.2 1.2 3.4e-24 85.4 0.3 1.9 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.5 EMC80225.1 - 2e-22 78.9 0.1 1.8e-21 75.9 0.0 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.6 EMC80225.1 - 6.7e-16 57.8 2.0 2.1e-15 56.2 0.3 2.4 2 0 0 2 2 2 1 FERM adjacent (FA) Ras PF00071.17 EMC80227.1 - 3.5e-53 179.2 0.0 4.2e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80227.1 - 1.2e-21 77.4 0.0 2e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC80227.1 - 1e-07 31.5 0.1 2.9e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMC80227.1 - 1.8e-06 27.2 0.0 2.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC80227.1 - 1.7e-05 24.7 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EMC80227.1 - 0.015 14.8 1.0 0.052 13.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EMC80227.1 - 0.023 14.6 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 EMC80227.1 - 0.038 13.1 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 EMC80227.1 - 0.19 11.2 1.0 0.29 10.7 0.1 1.7 2 1 0 2 2 2 0 AAA domain DUF1777 PF08648.7 EMC80228.1 - 4.2 7.0 191.9 1.5e+04 -75.6 133.0 4.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) LCM PF04072.9 EMC80231.1 - 2.7e-22 79.1 0.0 4.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.1 EMC80231.1 - 1.3e-10 40.9 1.9 0.84 9.6 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EMC80231.1 - 2.8e-08 33.3 6.3 1.8 8.3 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC80231.1 - 2.5e-06 27.4 10.4 0.0022 18.1 0.1 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EMC80231.1 - 1.2e-05 25.2 4.1 0.26 11.5 0.1 4.6 2 1 2 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EMC80231.1 - 0.00017 21.2 6.7 0.081 12.7 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EMC80231.1 - 0.00094 18.6 3.2 0.03 13.8 0.0 3.6 4 0 0 4 4 4 1 Kelch motif MRP-S33 PF08293.6 EMC80232.1 - 5.8e-30 103.1 3.6 7.2e-30 102.8 2.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Herpes_UL36 PF03586.8 EMC80232.1 - 0.059 12.4 0.1 0.073 12.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Pkinase_Tyr PF07714.12 EMC80233.1 - 1.9e-64 217.2 0.0 2.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC80233.1 - 1e-60 205.1 0.0 1.4e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.10 EMC80233.1 - 2.1e-30 104.2 0.0 3.7e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.17 EMC80233.1 - 7.4e-12 44.8 6.7 1.4e-11 43.8 4.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 EMC80233.1 - 2.1e-09 36.7 0.0 3.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.6 EMC80233.1 - 0.00059 19.7 2.6 0.0014 18.5 1.8 1.6 1 0 0 1 1 1 1 RING-like domain C1_3 PF07649.7 EMC80233.1 - 0.071 13.1 5.3 0.15 12.1 3.7 1.6 1 0 0 1 1 1 0 C1-like domain Kdo PF06293.9 EMC80233.1 - 0.082 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC80233.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_1 PF14446.1 EMC80233.1 - 0.23 11.2 1.8 0.54 10.0 1.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.11 EMC80233.1 - 0.81 9.6 9.2 1.6 8.6 6.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger DENN PF02141.16 EMC80234.1 - 6.8e-57 192.1 1.2 1.4e-56 191.2 0.8 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EMC80234.1 - 1e-22 79.8 0.3 2e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EMC80234.1 - 5.9e-22 77.5 2.6 1.3e-21 76.4 1.8 1.6 1 0 0 1 1 1 1 dDENN domain zf-CCCH PF00642.19 EMC80235.1 - 2.5e-14 52.5 35.0 1.1e-05 24.9 0.1 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EMC80235.1 - 1.4e-07 31.1 5.1 7.3e-07 28.9 3.6 2.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC80235.1 - 5.6e-07 29.1 7.1 5.6e-07 29.1 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC80235.1 - 1.5e-05 24.6 6.0 1.5e-05 24.6 4.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC80235.1 - 4.1e-05 23.6 6.0 4.1e-05 23.6 4.1 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC80235.1 - 0.00013 21.9 5.9 0.00013 21.9 4.1 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC80235.1 - 0.00091 19.0 3.6 0.00091 19.0 2.5 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC80235.1 - 0.0024 17.7 4.0 0.0024 17.7 2.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC80235.1 - 0.0024 17.5 2.8 0.0054 16.4 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_2 PF14608.1 EMC80235.1 - 0.0074 16.2 30.6 0.33 11.0 0.1 5.4 4 1 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type MFS_1 PF07690.11 EMC80236.1 - 2.9e-40 138.0 27.6 6.6e-37 127.0 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily JmjC PF02373.17 EMC80237.1 - 1.4e-10 41.3 5.8 3e-10 40.3 1.4 3.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EMC80237.1 - 7.9e-09 35.3 0.1 7.9e-09 35.3 0.1 2.8 3 0 0 3 3 3 1 Cupin-like domain AA_permease_2 PF13520.1 EMC80238.1 - 9.1e-52 176.0 38.8 1.1e-51 175.8 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC80238.1 - 2e-23 82.5 38.7 4.7e-23 81.2 25.3 1.8 1 1 1 2 2 2 1 Amino acid permease PARP PF00644.15 EMC80240.1 - 7.5e-43 146.3 0.3 2.4e-42 144.7 0.2 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Capsid_NCLDV PF04451.7 EMC80240.1 - 0.093 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Aldo_ket_red PF00248.16 EMC80241.1 - 6.4e-49 166.2 0.0 7.1e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bromodomain PF00439.20 EMC80242.1 - 2.5e-21 75.4 0.1 2.5e-21 75.4 0.1 2.0 2 0 0 2 2 2 1 Bromodomain zf-B_box PF00643.19 EMC80242.1 - 4.6e-11 42.4 24.1 5.3e-09 35.8 5.5 4.7 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.24 EMC80242.1 - 5.6e-09 35.5 10.1 5.6e-09 35.5 7.0 4.4 4 0 0 4 4 4 1 PHD-finger MFS_1 PF07690.11 EMC80243.1 - 7.1e-30 103.9 43.2 5.5e-22 77.9 15.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC80243.1 - 4.4e-22 78.2 35.9 2.3e-19 69.3 8.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter V_ATPase_I PF01496.14 EMC80244.1 - 5.9e-295 980.0 8.8 6.7e-295 979.8 6.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Neurensin PF14927.1 EMC80244.1 - 0.013 14.8 0.7 0.1 12.0 0.0 2.4 2 0 0 2 2 2 0 Neurensin TMEM213 PF15192.1 EMC80245.1 - 1.4e-32 111.4 2.5 1.5e-32 111.4 1.7 1.0 1 0 0 1 1 1 1 TMEM213 family WAP PF00095.16 EMC80245.1 - 0.037 13.9 1.1 0.052 13.5 0.8 1.2 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' p450 PF00067.17 EMC80246.1 - 1.7e-100 336.7 1.1 9.3e-70 235.4 0.1 3.0 3 0 0 3 3 3 3 Cytochrome P450 PARP PF00644.15 EMC80247.1 - 5.2e-41 140.3 2.1 2.2e-40 138.3 1.4 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-CCCH PF00642.19 EMC80247.1 - 3.5e-05 23.3 2.4 3.5e-05 23.3 1.7 3.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WWE PF02825.15 EMC80247.1 - 4.6e-05 22.7 1.0 4.6e-05 22.7 0.7 2.5 2 0 0 2 2 2 1 WWE domain Ets PF00178.17 EMC80249.1 - 1.4e-24 86.0 0.8 2.2e-24 85.3 0.5 1.3 1 0 0 1 1 1 1 Ets-domain I-set PF07679.11 EMC80250.1 - 2e-96 315.9 2.4 3.2e-20 71.7 0.0 7.6 7 0 0 7 7 7 7 Immunoglobulin I-set domain fn3 PF00041.16 EMC80250.1 - 1.5e-45 153.1 1.7 4.3e-14 52.4 0.0 5.3 5 0 0 5 5 5 3 Fibronectin type III domain Ig_2 PF13895.1 EMC80250.1 - 2.6e-45 152.4 0.1 3.4e-10 39.9 0.0 7.6 5 1 1 7 7 7 7 Immunoglobulin domain ig PF00047.20 EMC80250.1 - 1.2e-24 86.1 0.3 6.1e-06 26.2 0.0 8.3 8 0 0 8 8 8 4 Immunoglobulin domain V-set PF07686.12 EMC80250.1 - 1.2e-23 83.1 2.9 0.00023 21.0 0.0 8.1 6 2 1 7 7 7 4 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC80250.1 - 2e-22 79.4 0.7 2.1e-08 34.5 0.0 6.7 7 1 0 7 7 7 4 Immunoglobulin domain C2-set_2 PF08205.7 EMC80250.1 - 5.4e-11 42.2 0.5 0.036 13.9 0.0 6.6 7 1 0 7 7 7 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC80250.1 - 2.5e-07 30.5 3.2 3.3 7.7 0.0 6.0 6 0 0 6 6 6 1 Immunoglobulin C1-set domain Herpes_gI PF01688.12 EMC80250.1 - 0.0032 16.5 0.0 3.4 6.7 0.0 4.5 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein I DUF4251 PF14059.1 EMC80250.1 - 0.0033 17.2 0.3 4.7 7.0 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4251) DUF3016 PF11454.3 EMC80250.1 - 0.073 12.6 0.0 0.64 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) V-set_CD47 PF08204.6 EMC80250.1 - 0.08 12.7 0.3 11 5.8 0.0 3.2 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain CDP-OH_P_transf PF01066.16 EMC80251.1 - 1.5e-15 57.3 1.1 1.5e-15 57.3 0.7 2.8 2 1 1 3 3 3 1 CDP-alcohol phosphatidyltransferase PHO4 PF01384.15 EMC80251.1 - 0.91 8.1 8.5 0.96 8.0 5.0 1.7 1 1 0 1 1 1 0 Phosphate transporter family Cor1 PF04803.7 EMC80252.1 - 1.2e-58 196.4 28.0 1.2e-58 196.4 19.4 1.5 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region UPF0020 PF01170.13 EMC80252.1 - 1.6 8.2 7.7 3 7.3 0.7 2.5 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Vac_Fusion PF02346.11 EMC80252.1 - 2.9 7.3 8.4 0.74 9.2 2.0 2.9 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Notch PF00066.12 EMC80253.1 - 6.8e-20 71.0 32.5 2.8e-11 43.4 9.4 2.4 2 0 0 2 2 2 2 LNR domain DMAP_binding PF06464.6 EMC80253.1 - 1.9e-10 41.2 0.2 6.5e-10 39.5 0.1 2.0 1 0 0 1 1 1 1 DMAP1-binding Domain DUF3184 PF11380.3 EMC80253.1 - 1.8e-07 29.5 4.1 0.0011 16.9 0.2 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3184) EF-hand_1 PF00036.27 EMC80253.1 - 0.023 13.9 0.0 0.065 12.5 0.0 1.9 1 0 0 1 1 1 0 EF hand Vanabin-2 PF11437.3 EMC80253.1 - 1.2 9.1 6.4 13 5.8 0.8 2.6 2 0 0 2 2 2 0 Vanadium-binding protein 2 DUF2360 PF10152.4 EMC80255.1 - 6.9e-46 156.1 0.2 8.3e-46 155.9 0.1 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) WD40 PF00400.27 EMC80256.1 - 2.2e-16 59.0 3.1 2.7e-09 36.5 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EMC80256.1 - 0.075 11.1 0.0 0.11 10.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 UvrD_C PF13361.1 EMC80257.1 - 1.6e-05 24.5 0.1 2.9e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Pro-MCH PF05824.7 EMC80258.1 - 4.1e-32 109.5 0.0 6.5e-32 108.8 0.0 1.3 1 0 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) RVT_1 PF00078.22 EMC80259.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Insulin PF00049.13 EMC80260.1 - 4e-14 53.1 8.5 4.5e-12 46.5 4.1 2.7 2 1 0 2 2 2 1 Insulin/IGF/Relaxin family Biopterin_H PF00351.16 EMC80261.1 - 3e-174 578.4 1.1 3.7e-174 578.1 0.8 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Biopterin_H PF00351.16 EMC80262.1 - 1.2e-187 622.4 0.2 2.3e-187 621.5 0.1 1.4 2 0 0 2 2 2 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EMC80262.1 - 5e-09 35.4 0.0 1.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EMC80262.1 - 0.00011 22.5 0.0 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 EMC80262.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 ACT domain 5_nucleotid PF05761.9 EMC80263.1 - 3.4e-164 546.6 6.6 3.9e-164 546.4 4.6 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 EMC80263.1 - 0.00061 20.0 2.0 0.061 13.5 0.4 3.7 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Condensin2nSMC PF12422.3 EMC80263.1 - 0.1 12.3 0.4 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Mu-transpos_C PF09299.6 EMC80263.1 - 0.12 12.2 1.0 0.78 9.6 0.1 2.8 2 0 0 2 2 2 0 Mu transposase, C-terminal HSP90 PF00183.13 EMC80264.1 - 1.9e-236 785.6 32.8 1.9e-236 785.6 22.7 1.6 2 0 0 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 EMC80264.1 - 4.6e-13 49.0 0.6 1.8e-12 47.1 0.4 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC80264.1 - 6.5e-12 45.1 0.3 1.2e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MH1 PF03165.11 EMC80264.1 - 0.12 12.3 0.6 0.96 9.4 0.0 2.8 2 0 0 2 2 2 0 MH1 domain DUF4516 PF14990.1 EMC80265.1 - 5.1e-11 41.9 0.1 6.2e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) UDG PF03167.14 EMC80266.1 - 1.1e-16 60.7 0.0 1.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GAGA_bind PF06217.7 EMC80266.1 - 0.12 12.3 3.6 0.2 11.5 2.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family UCH PF00443.24 EMC80267.1 - 2.2e-43 148.3 4.1 2.6e-43 148.1 2.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC80267.1 - 2.5e-27 96.0 4.0 3.6e-27 95.5 2.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tubulin PF00091.20 EMC80268.1 - 1.1e-69 234.5 0.0 1.5e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC80268.1 - 1.1e-50 170.8 0.0 1.8e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC80268.1 - 0.0034 16.8 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EMC80269.1 - 4.3e-69 232.6 0.0 5.6e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC80269.1 - 5.5e-50 168.6 0.0 9.3e-50 167.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC80269.1 - 0.00078 18.9 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pex26 PF07163.7 EMC80270.1 - 8.8e-81 271.1 2.1 1e-80 270.9 1.5 1.0 1 0 0 1 1 1 1 Pex26 protein CH PF00307.26 EMC80271.1 - 2.1e-18 66.3 0.0 8e-18 64.4 0.0 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC80271.1 - 3.5e-12 45.8 0.0 1.1e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.17 EMC80271.1 - 2.7e-09 36.9 10.7 5.2e-09 36.0 7.4 1.5 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.14 EMC80271.1 - 1.5e-05 24.2 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC80271.1 - 0.00056 18.9 0.1 0.0015 17.5 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMC80271.1 - 0.00061 18.3 0.0 0.0011 17.5 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMC80271.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC80271.1 - 0.00063 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMC80271.1 - 0.0018 18.6 0.1 0.0072 16.7 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC80271.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMC80271.1 - 0.0031 17.7 0.0 0.0096 16.1 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Thi4 PF01946.12 EMC80271.1 - 0.0034 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EMC80271.1 - 0.0064 16.4 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMC80271.1 - 0.021 13.7 0.0 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EMC80271.1 - 0.04 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BID PF06393.6 EMC80272.1 - 7.6e-57 191.8 0.6 8.3e-57 191.7 0.4 1.0 1 0 0 1 1 1 1 BH3 interacting domain (BID) DUF1546 PF07571.8 EMC80272.1 - 0.0099 15.9 0.1 5.4 7.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1546) RhoGAP PF00620.22 EMC80272.1 - 0.032 13.8 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 RhoGAP domain Bcl-2 PF00452.14 EMC80273.1 - 2.9e-11 43.3 0.0 5.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family DUF842 PF05811.8 EMC80273.1 - 0.054 12.9 0.1 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF883 PF05957.8 EMC80273.1 - 0.11 12.8 1.3 0.74 10.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3770 PF12603.3 EMC80273.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) DUF4549 PF15082.1 EMC80273.1 - 0.21 11.2 1.9 0.54 9.8 1.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) Mnd1 PF03962.10 EMC80273.1 - 0.26 10.9 3.4 0.81 9.3 2.2 1.7 1 1 0 1 1 1 0 Mnd1 family vATP-synt_E PF01991.13 EMC80274.1 - 1.1e-71 240.2 10.9 1.2e-71 240.0 7.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit NifW PF03206.9 EMC80274.1 - 0.028 14.5 3.1 0.038 14.0 1.6 1.6 1 1 0 1 1 1 0 Nitrogen fixation protein NifW ATP-synt_B PF00430.13 EMC80274.1 - 0.042 13.6 0.6 0.042 13.6 0.4 2.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4288 PF14119.1 EMC80274.1 - 0.043 13.9 2.6 0.91 9.6 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF4026 PF13218.1 EMC80274.1 - 0.26 10.1 3.0 0.33 9.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) A_deaminase PF00962.17 EMC80275.1 - 1.2e-59 201.9 0.0 1.8e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EMC80275.1 - 8.6e-22 76.9 0.0 1.6e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Hydrolase_like PF13242.1 EMC80276.1 - 1.5e-06 27.8 0.0 0.00026 20.6 0.0 2.5 2 0 0 2 2 2 2 HAD-hyrolase-like Prenyltrans_1 PF13243.1 EMC80276.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Prenyltransferase-like VWA_N PF08399.6 EMC80278.1 - 7.2e-42 142.8 0.3 1.4e-41 141.9 0.2 1.5 1 0 0 1 1 1 1 VWA N-terminal Cache_1 PF02743.13 EMC80278.1 - 6.5e-26 89.7 0.1 2.9e-24 84.4 0.0 2.9 3 0 0 3 3 3 1 Cache domain VWA_3 PF13768.1 EMC80278.1 - 2.8e-16 59.5 0.0 5.3e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC80278.1 - 3.9e-15 56.3 0.0 7.6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMC80278.1 - 7.8e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMC80278.1 - 0.05 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CobT_C PF11775.3 EMC80278.1 - 0.16 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain LRR_8 PF13855.1 EMC80279.1 - 6.1e-30 102.7 30.0 8.5e-12 44.6 0.4 3.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EMC80279.1 - 3.9e-13 48.6 16.3 0.00021 20.8 0.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.13 EMC80279.1 - 2e-09 36.6 3.3 9.2e-09 34.5 2.4 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 EMC80279.1 - 5e-08 32.7 0.0 9.6e-07 28.5 0.0 2.4 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC80279.1 - 1.1e-07 30.8 16.6 0.13 12.5 0.1 6.3 6 0 0 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 EMC80279.1 - 2.8e-07 29.6 26.1 0.0083 16.0 0.5 6.7 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_9 PF14580.1 EMC80279.1 - 0.0061 16.1 2.1 0.081 12.4 0.4 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EMC80279.1 - 0.56 10.4 17.1 7.3 7.0 0.3 5.4 5 0 0 5 5 5 0 Leucine Rich repeat HlyIII PF03006.15 EMC80280.1 - 8.3e-71 237.9 23.3 1.2e-70 237.4 16.1 1.2 1 0 0 1 1 1 1 Haemolysin-III related FeoB_C PF07664.7 EMC80280.1 - 3.3 7.2 7.0 6.2 6.3 0.4 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus wnt PF00110.14 EMC80281.1 - 2.2e-120 401.5 22.5 2.5e-120 401.3 15.6 1.0 1 0 0 1 1 1 1 wnt family LRR_6 PF13516.1 EMC80282.1 - 2.8e-21 73.1 41.1 0.039 14.0 0.1 11.9 12 0 0 12 12 12 9 Leucine Rich repeat LRR_4 PF12799.2 EMC80282.1 - 6e-16 57.6 19.4 0.0066 16.0 0.7 7.3 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC80282.1 - 3.3e-13 47.6 27.1 1.3 9.3 0.0 10.9 9 2 1 10 10 10 4 Leucine Rich Repeat LRR_8 PF13855.1 EMC80282.1 - 2.1e-09 37.0 29.3 0.026 14.2 3.3 6.2 2 2 3 6 6 6 6 Leucine rich repeat LRR_7 PF13504.1 EMC80282.1 - 0.0014 18.4 37.6 16 6.2 0.1 11.3 11 1 1 12 12 12 1 Leucine rich repeat Ste50p-SAM PF09235.5 EMC80282.1 - 0.0027 17.6 4.5 0.22 11.5 0.2 4.4 4 1 1 5 5 5 1 Ste50p, sterile alpha motif LRR_2 PF07723.8 EMC80282.1 - 0.0055 17.1 12.6 2.8 8.6 0.0 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat Bac_DnaA_C PF08299.6 EMC80282.1 - 0.061 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix Antiterm PF03589.8 EMC80282.1 - 0.14 12.2 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Antitermination protein Cast PF10174.4 EMC80283.1 - 6.1e-268 890.9 162.3 7e-268 890.8 112.5 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 EMC80283.1 - 0.00026 20.8 26.5 0.00073 19.4 6.2 9.6 1 1 7 8 8 8 4 Autophagy protein 16 (ATG16) DUF869 PF05911.6 EMC80283.1 - 0.0018 16.6 17.7 0.0018 16.6 12.3 5.4 1 1 4 5 5 5 2 Plant protein of unknown function (DUF869) IncA PF04156.9 EMC80283.1 - 2.2 7.8 159.2 0.02 14.4 13.3 8.4 1 1 6 7 7 7 0 IncA protein Rad52_Rad22 PF04098.10 EMC80284.1 - 9.3e-54 181.3 0.8 1.1e-53 181.1 0.0 1.5 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein Sds3 PF08598.6 EMC80284.1 - 2.4 7.6 9.6 6 6.3 6.7 1.7 1 1 0 1 1 1 0 Sds3-like Ninjurin PF04923.7 EMC80285.1 - 3.4e-32 110.2 10.0 3.9e-32 110.0 7.0 1.0 1 0 0 1 1 1 1 Ninjurin DUF1418 PF07214.7 EMC80285.1 - 0.12 12.0 2.6 0.25 10.9 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) SHP PF03579.8 EMC80285.1 - 2.6 7.4 11.1 0.045 13.1 1.9 2.1 1 1 1 2 2 2 0 Small hydrophobic protein Surp PF01805.15 EMC80286.1 - 0.017 14.7 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 Surp module PLU-1 PF08429.6 EMC80287.1 - 2.1e-99 332.6 28.0 1e-98 330.3 9.5 3.9 3 1 0 3 3 3 2 PLU-1-like protein JmjC PF02373.17 EMC80287.1 - 7.4e-46 155.0 1.4 2.3e-45 153.5 0.9 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EMC80287.1 - 2.2e-29 100.8 36.7 4.1e-12 45.5 2.3 3.8 3 0 0 3 3 3 3 PHD-finger ARID PF01388.16 EMC80287.1 - 2.9e-24 84.7 0.1 1.5e-23 82.4 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EMC80287.1 - 1.5e-17 63.3 12.4 1.5e-17 63.3 8.6 3.5 3 0 0 3 3 3 1 C5HC2 zinc finger SNF PF00209.13 EMC80288.1 - 3.9e-246 817.5 36.8 4.5e-246 817.3 25.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3671 PF12420.3 EMC80288.1 - 3.3 7.7 17.7 0.11 12.4 0.4 3.9 3 2 0 3 3 3 0 Protein of unknown function SNF PF00209.13 EMC80289.1 - 2.5e-243 808.3 36.8 2.8e-243 808.1 25.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 EMC80290.1 - 3.3e-229 761.7 40.1 3.8e-229 761.5 27.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TM231 PF10149.4 EMC80290.1 - 0.009 15.0 1.1 0.019 13.9 0.7 1.4 1 0 0 1 1 1 1 Transmembrane protein 231 Sec7 PF01369.15 EMC80291.1 - 2.6e-60 203.3 0.0 6.7e-60 202.0 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain IQ PF00612.22 EMC80291.1 - 0.059 13.0 1.3 0.19 11.4 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif zf-H2C2_2 PF13465.1 EMC80292.1 - 3.7e-87 282.6 85.2 6.5e-11 41.9 0.3 13.4 13 1 0 13 13 13 13 Zinc-finger double domain zf-C2H2 PF00096.21 EMC80292.1 - 3.7e-77 250.2 91.0 2.2e-07 30.8 1.5 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80292.1 - 2.2e-42 140.2 82.3 0.00011 22.2 0.5 12.2 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC80292.1 - 2e-35 119.5 74.0 4.8e-05 23.1 0.3 12.2 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC80292.1 - 8.6e-28 95.7 46.6 0.0031 17.5 0.0 12.2 12 0 0 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC80292.1 - 1.3e-11 44.2 74.8 0.099 12.8 0.2 11.9 12 0 0 12 12 12 8 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.2 EMC80292.1 - 4.1e-07 29.7 62.3 0.22 11.3 1.6 8.7 7 2 0 8 8 8 6 Transposase zinc-ribbon domain Prok-RING_1 PF14446.1 EMC80292.1 - 1.5e-06 27.7 37.4 8.2 6.2 0.0 11.6 11 1 1 12 12 12 0 Prokaryotic RING finger family 1 XPA_N PF01286.13 EMC80292.1 - 2.7e-06 26.9 55.5 1.1 8.9 0.9 11.8 12 0 0 12 12 12 4 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EMC80292.1 - 8.7e-05 22.3 77.9 0.86 9.6 3.9 11.0 5 5 3 8 8 8 5 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 EMC80292.1 - 0.0011 18.3 49.5 2.5 7.6 0.1 11.8 12 0 0 12 12 12 1 DNA directed RNA polymerase, 7 kDa subunit LIM PF00412.17 EMC80292.1 - 0.02 14.9 54.3 0.15 12.1 0.4 8.6 4 3 5 9 9 9 0 LIM domain Raffinose_syn PF05691.7 EMC80292.1 - 0.026 12.0 0.7 4.2 4.7 0.0 3.6 3 1 0 4 4 4 0 Raffinose synthase or seed imbibition protein Sip1 BolA PF01722.13 EMC80292.1 - 0.056 13.4 11.4 9.1 6.3 0.0 5.3 3 1 0 3 3 3 0 BolA-like protein Rad50_zn_hook PF04423.9 EMC80292.1 - 0.062 12.7 3.7 0.43 10.0 0.0 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif FYDLN_acid PF09538.5 EMC80292.1 - 0.79 10.3 34.3 28 5.3 0.5 9.7 2 2 6 9 9 9 0 Protein of unknown function (FYDLN_acid) C1_4 PF07975.7 EMC80292.1 - 1.3 9.0 56.8 1 9.4 4.1 9.1 2 2 10 12 12 12 0 TFIIH C1-like domain zf-Di19 PF05605.7 EMC80292.1 - 3.1 7.9 55.7 0.055 13.5 1.4 7.5 4 3 4 8 8 7 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EMC80292.1 - 3.5 7.2 29.3 7.7 6.1 0.0 7.4 3 2 5 8 8 8 0 GAGA factor zf-C2H2_2 PF12756.2 EMC80292.1 - 8.7 6.5 54.9 36 4.5 0.0 10.0 1 1 10 11 11 9 0 C2H2 type zinc-finger (2 copies) GF_recep_IV PF14843.1 EMC80292.1 - 9 5.9 42.0 0.095 12.3 5.6 4.3 1 1 2 4 4 4 0 Growth factor receptor domain IV PBP_sp32 PF07222.7 EMC80293.1 - 4e-31 108.0 0.4 4.6e-31 107.8 0.3 1.0 1 0 0 1 1 1 1 Proacrosin binding protein sp32 DUF640 PF04852.7 EMC80293.1 - 0.019 15.1 0.1 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF640) IBN_N PF03810.14 EMC80294.1 - 1.1e-21 76.5 0.3 2.6e-18 65.7 0.0 4.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 EMC80294.1 - 2.1e-09 36.4 3.9 2.1e-09 36.4 2.7 3.0 2 1 0 3 3 3 1 Cse1 DUF1539 PF07560.6 EMC80294.1 - 0.0071 16.2 1.9 0.23 11.3 0.0 3.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) PPP4R2 PF09184.6 EMC80294.1 - 0.028 13.9 0.1 0.028 13.9 0.0 3.0 3 0 0 3 3 3 0 PPP4R2 HEAT_2 PF13646.1 EMC80294.1 - 0.039 14.2 0.0 13 6.0 0.0 3.8 3 0 0 3 3 3 0 HEAT repeats Xpo1 PF08389.7 EMC80294.1 - 0.63 9.9 13.0 0.094 12.6 0.4 4.2 4 1 0 4 4 4 0 Exportin 1-like protein FAM60A PF15396.1 EMC80295.1 - 2.5e-88 295.3 11.2 2.9e-88 295.1 7.8 1.0 1 0 0 1 1 1 1 Protein Family FAM60A DUF2706 PF10913.3 EMC80295.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) PrmA PF06325.8 EMC80296.1 - 1.6e-10 40.6 0.1 2.4e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EMC80296.1 - 1.6e-09 37.4 0.0 4e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EMC80296.1 - 7.2e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC80296.1 - 0.001 19.6 0.1 0.0022 18.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMC80296.1 - 0.0025 17.4 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EMC80296.1 - 0.0046 16.3 0.0 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMC80296.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EMC80296.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 LRR_6 PF13516.1 EMC80297.1 - 1.3e-14 52.5 8.2 0.024 14.6 0.0 6.4 5 1 1 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.2 EMC80297.1 - 6.3e-06 25.6 3.0 0.0035 16.9 0.6 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC80297.1 - 0.035 14.1 8.7 26 5.3 0.0 5.4 4 3 1 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.1 EMC80297.1 - 0.11 12.3 5.8 1.2 8.9 0.4 3.8 3 2 1 4 4 4 0 Leucine rich repeat Pentapeptide_3 PF13576.1 EMC80297.1 - 0.16 11.9 1.3 7.7 6.4 0.1 3.3 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) Adeno_E4_34 PF04528.8 EMC80297.1 - 0.24 11.0 8.0 0.13 11.9 0.4 2.5 1 1 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region LRR_2 PF07723.8 EMC80297.1 - 8.3 7.0 8.5 29 5.3 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4617 PF15395.1 EMC80298.1 - 8.7e-274 911.4 109.1 8.7e-274 911.4 75.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4617) BicD PF09730.4 EMC80299.1 - 0 1114.9 67.3 0 1114.7 46.7 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF869 PF05911.6 EMC80299.1 - 4.3e-05 21.9 68.5 0.0022 16.3 7.0 4.1 2 1 2 4 4 4 3 Plant protein of unknown function (DUF869) DUF1759 PF03564.10 EMC80299.1 - 0.0011 18.8 7.1 0.0011 18.8 4.9 5.3 4 1 0 5 5 5 1 Protein of unknown function (DUF1759) ApoO PF09769.4 EMC80299.1 - 0.38 10.4 11.5 0.61 9.7 0.1 3.7 3 0 0 3 3 3 0 Apolipoprotein O RhoGEF PF00621.15 EMC80300.1 - 7.5e-48 162.7 0.7 7.5e-48 162.7 0.5 1.7 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EMC80300.1 - 8.8e-23 80.4 0.8 1e-12 48.1 0.1 3.0 2 0 0 2 2 2 2 PH domain FYVE PF01363.16 EMC80300.1 - 2e-18 66.0 11.2 5.2e-18 64.7 7.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_11 PF15413.1 EMC80300.1 - 1.4e-06 28.5 0.4 0.062 13.5 0.0 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain FYVE_2 PF02318.11 EMC80300.1 - 0.0011 18.8 12.1 0.0057 16.5 8.3 2.5 1 1 0 1 1 1 1 FYVE-type zinc finger PH_6 PF15406.1 EMC80300.1 - 0.0012 18.8 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain zf-RING_5 PF14634.1 EMC80300.1 - 0.12 12.0 12.9 0.29 10.8 8.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain IBR PF01485.16 EMC80300.1 - 0.13 12.1 11.7 0.042 13.7 5.5 2.1 1 1 0 1 1 1 0 IBR domain Presenilin PF01080.12 EMC80300.1 - 0.16 10.7 2.1 0.3 9.8 1.4 1.4 1 0 0 1 1 1 0 Presenilin PH_5 PF15405.1 EMC80300.1 - 0.3 11.0 3.8 3.5 7.5 0.0 3.2 2 1 1 3 3 3 0 Pleckstrin homology domain zf-C3HC4_2 PF13923.1 EMC80300.1 - 9.6 6.3 11.7 40 4.3 8.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dynamin_M PF01031.15 EMC80301.1 - 1.3e-100 336.0 0.1 3.1e-100 334.7 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EMC80301.1 - 2.6e-50 170.5 0.6 1e-49 168.6 0.1 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EMC80301.1 - 1.4e-32 111.4 2.8 4.9e-32 109.6 1.9 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF3544 PF12064.3 EMC80301.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) tRNA-synt_1b PF00579.20 EMC80302.1 - 4.4e-31 108.0 0.0 5.4e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EMC80302.1 - 0.0091 15.4 0.1 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain PDZ PF00595.19 EMC80303.1 - 5.2e-84 276.4 24.9 9.5e-16 57.7 0.2 7.2 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC80303.1 - 1.7e-29 101.5 16.6 1.4e-06 28.0 0.5 6.8 6 1 1 7 7 7 6 PDZ domain PDZ_1 PF12812.2 EMC80303.1 - 0.053 13.4 0.1 21 5.1 0.0 3.2 3 0 0 3 3 3 0 PDZ-like domain LURAP PF14854.1 EMC80304.1 - 1.1e-40 138.1 1.5 1.4e-40 137.8 1.0 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein Tyrosinase PF00264.15 EMC80305.1 - 4.5e-33 115.2 0.1 6.3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase TMEM154 PF15102.1 EMC80305.1 - 0.072 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Laminin_EGF PF00053.19 EMC80305.1 - 0.52 10.2 13.3 1 9.3 7.0 2.7 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EMC80305.1 - 1.1 9.4 15.6 0.12 12.4 3.1 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Yae1_N PF09811.4 EMC80306.1 - 1.5e-09 37.2 34.0 0.087 12.3 17.6 4.3 2 2 0 2 2 2 2 Essential protein Yae1, N terminal PSP1 PF04468.7 EMC80307.1 - 0.012 15.5 0.4 0.035 14.0 0.1 1.8 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Y_phosphatase PF00102.22 EMC80308.1 - 4.5e-172 569.4 0.4 5e-86 287.8 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 EMC80308.1 - 6.5e-112 365.9 28.7 1.2e-16 60.5 0.2 10.3 10 1 0 10 10 9 8 Fibronectin type III domain I-set PF07679.11 EMC80308.1 - 2.6e-22 78.4 0.0 2.8e-12 46.3 0.0 3.5 4 0 0 4 4 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC80308.1 - 1e-15 57.9 3.5 2.5e-05 24.6 0.0 5.8 6 0 0 6 6 5 2 Immunoglobulin domain Ig_2 PF13895.1 EMC80308.1 - 2.5e-15 56.3 0.1 3e-08 33.6 0.0 3.5 3 0 0 3 3 2 2 Immunoglobulin domain Interfer-bind PF09294.5 EMC80308.1 - 4.8e-11 42.6 0.4 0.3 11.1 0.0 7.4 7 0 0 7 7 7 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.15 EMC80308.1 - 2.6e-08 33.5 0.0 0.0038 16.8 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC80308.1 - 1.3e-06 28.7 0.0 0.068 13.4 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC80308.1 - 1.7e-06 28.1 0.1 0.0022 18.0 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate V-set PF07686.12 EMC80308.1 - 0.0021 17.9 0.0 0.63 9.9 0.0 3.5 2 1 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC80308.1 - 0.0081 16.0 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.4 EMC80308.1 - 0.0091 15.1 0.3 28 3.6 0.0 4.7 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) LBR_tudor PF09465.5 EMC80309.1 - 0.00029 20.3 0.1 0.00056 19.4 0.1 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain CopK PF11525.3 EMC80309.1 - 0.012 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein K JmjC PF02373.17 EMC80310.1 - 8.4e-41 138.7 0.1 1.9e-40 137.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SAD_SRA PF02182.12 EMC80311.1 - 2.2e-53 179.7 0.0 4.6e-53 178.6 0.0 1.6 1 0 0 1 1 1 1 SAD/SRA domain DUF3590 PF12148.3 EMC80311.1 - 3e-37 126.0 1.2 1e-32 111.5 0.3 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3590) PHD PF00628.24 EMC80311.1 - 7.2e-10 38.4 10.7 7.2e-10 38.4 7.4 3.5 2 2 1 3 3 3 1 PHD-finger zf-C3HC4_2 PF13923.1 EMC80311.1 - 0.00026 20.9 13.3 0.00026 20.9 9.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC80311.1 - 0.00042 19.9 13.3 0.00042 19.9 9.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EMC80311.1 - 0.0013 17.9 2.6 0.0013 17.9 1.8 3.5 3 0 0 3 3 3 1 PHD-finger zf-RING_5 PF14634.1 EMC80311.1 - 0.0022 17.6 12.9 0.0022 17.6 8.9 3.5 2 1 0 2 2 2 1 zinc-RING finger domain ubiquitin PF00240.18 EMC80311.1 - 0.05 13.0 0.3 0.23 10.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family GUCT PF08152.7 EMC80312.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 GUCT (NUC152) domain MLANA PF14991.1 EMC80315.1 - 1.7e-44 150.6 0.0 1.9e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein melan-A DUF4131 PF13567.1 EMC80315.1 - 0.011 15.1 1.2 0.014 14.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 EMC80316.1 - 1.6e-34 119.1 42.1 1.8e-26 92.7 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC80316.1 - 1.4e-06 26.9 2.8 1.4e-06 26.9 1.9 3.0 1 1 2 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 EMC80316.1 - 7.3e-05 21.4 9.1 7.3e-05 21.4 6.3 2.5 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like DUF1290 PF06947.7 EMC80316.1 - 2.5 8.0 8.4 5.2 7.0 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1290) RIC1 PF07064.8 EMC80318.1 - 9.3e-91 303.8 0.7 1.5e-90 303.1 0.5 1.3 1 0 0 1 1 1 1 RIC1 Ig_2 PF13895.1 EMC80319.1 - 1.5e-10 41.0 0.1 0.00029 20.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC80319.1 - 3.4e-08 33.3 0.1 4.1e-07 29.8 0.0 2.1 1 1 1 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC80319.1 - 8.5e-08 32.5 1.9 0.00039 20.8 0.1 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC80319.1 - 1.3e-07 31.6 0.2 0.00023 21.1 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC80319.1 - 4.2e-06 26.5 0.2 0.056 13.3 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain C1-set PF07654.10 EMC80319.1 - 0.00024 21.0 0.2 0.00076 19.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC80319.1 - 0.0033 17.2 0.1 0.026 14.4 0.0 2.3 1 1 1 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC80320.1 - 5.7e-13 48.7 0.3 4.1e-12 45.9 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 EMC80320.1 - 4.9e-12 45.5 0.3 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC80320.1 - 7e-12 45.3 0.4 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC80320.1 - 2.6e-10 40.6 1.3 0.00066 20.1 0.3 3.0 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC80320.1 - 1.8e-06 27.7 0.2 8.8e-05 22.3 0.2 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC80320.1 - 2.5e-06 27.5 1.1 0.023 14.8 0.0 3.5 2 2 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.10 EMC80320.1 - 0.00016 21.6 1.4 0.0044 16.9 0.5 2.5 3 0 0 3 3 3 1 Immunoglobulin C1-set domain DUF2368 PF10166.4 EMC80321.1 - 3.4e-43 146.3 0.0 3.9e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Insulin PF00049.13 EMC80322.1 - 0.013 16.2 0.1 0.014 16.1 0.1 1.3 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family Ins_beta PF03488.9 EMC80322.1 - 0.044 13.5 0.8 0.067 13.0 0.6 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Pkinase_Tyr PF07714.12 EMC80323.1 - 5.6e-147 487.7 0.0 7.5e-87 290.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EMC80323.1 - 6.1e-75 251.7 0.0 9.5e-50 169.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 EMC80323.1 - 6.8e-06 25.2 0.0 0.00036 19.5 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC80323.1 - 8.6e-05 21.6 0.3 0.078 12.0 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC80323.1 - 0.001 18.4 1.3 0.19 11.0 0.1 2.5 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 EMC80323.1 - 0.056 13.1 0.0 2.8 7.5 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RTC PF01137.16 EMC80324.1 - 6.1e-58 195.2 0.0 7.4e-58 195.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EMC80324.1 - 1.3e-32 111.8 0.0 1.9e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Flavokinase PF01687.12 EMC80325.1 - 7.1e-14 51.7 0.3 8.2e-14 51.5 0.2 1.1 1 0 0 1 1 1 1 Riboflavin kinase Peptidase_S8 PF00082.17 EMC80326.1 - 2.3e-57 194.3 2.7 3.7e-57 193.6 1.9 1.4 1 0 0 1 1 1 1 Subtilase family GF_recep_IV PF14843.1 EMC80326.1 - 2.1e-35 121.2 386.4 5.6e-09 35.7 28.6 13.9 3 2 11 14 14 14 10 Growth factor receptor domain IV P_proprotein PF01483.15 EMC80326.1 - 1.9e-31 107.6 0.0 3.6e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain VSP PF03302.8 EMC80326.1 - 6.1e-22 77.8 335.5 0.00029 19.6 16.7 18.1 3 2 11 15 15 15 12 Giardia variant-specific surface protein Furin-like PF00757.15 EMC80326.1 - 2.2e-06 27.4 377.7 0.00031 20.4 23.1 14.3 1 1 10 12 12 12 6 Furin-like cysteine rich region UPF0104 PF03706.8 EMC80326.1 - 1.2 8.3 0.0 1.7 7.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) BatD PF13584.1 EMC80326.1 - 1.4 7.4 0.0 2.1 6.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Ank_2 PF12796.2 EMC80327.1 - 9.7e-35 118.7 9.6 2.5e-18 66.1 0.3 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC80327.1 - 1.5e-23 82.2 3.7 6.6e-11 42.0 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC80327.1 - 5.4e-19 66.9 1.2 8.4e-08 31.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat SH3_1 PF00018.23 EMC80327.1 - 6.6e-17 60.6 0.0 1.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_4 PF13637.1 EMC80327.1 - 7.2e-17 61.4 0.8 1.1e-08 35.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_9 PF14604.1 EMC80327.1 - 3.3e-15 55.3 0.1 5.6e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.1 EMC80327.1 - 7.9e-15 53.4 0.3 0.0019 18.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat SH3_2 PF07653.12 EMC80327.1 - 3.3e-13 48.9 0.0 6.8e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_18 PF13238.1 EMC80328.1 - 1.3e-14 54.5 0.0 5.5e-14 52.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC80328.1 - 2.1e-06 28.5 0.1 7.3e-06 26.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMC80328.1 - 0.07 13.0 0.2 0.57 10.1 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase N2227 PF07942.7 EMC80329.1 - 4e-112 373.6 0.2 5e-112 373.3 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein RhoGAP PF00620.22 EMC80329.1 - 0.02 14.5 0.5 0.75 9.3 0.2 2.3 1 1 1 2 2 2 0 RhoGAP domain Methyltransf_23 PF13489.1 EMC80329.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMC80329.1 - 0.024 15.1 0.0 0.08 13.4 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.1 EMC80329.1 - 0.057 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMC80329.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Alpha_kinase PF02816.13 EMC80330.1 - 2.1e-44 151.4 0.2 6e-44 149.9 0.0 2.0 2 0 0 2 2 2 1 Alpha-kinase family Ion_trans PF00520.26 EMC80330.1 - 2.4e-07 30.2 11.9 7.1e-07 28.6 8.2 1.9 1 0 0 1 1 1 1 Ion transport protein zf-C4 PF00105.13 EMC80331.1 - 2.1e-33 114.3 12.3 4.9e-33 113.1 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC80331.1 - 2.6e-29 101.8 1.9 2.6e-29 101.8 1.3 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Ras PF00071.17 EMC80332.1 - 3.2e-42 143.6 0.0 3.8e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80332.1 - 8e-18 65.0 0.0 1.2e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC80332.1 - 8.3e-10 38.1 0.0 8.9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC80332.1 - 1.8e-07 30.5 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC80332.1 - 0.0015 17.9 0.1 0.042 13.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMC80332.1 - 0.0057 16.7 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMC80332.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EMC80332.1 - 0.041 13.3 0.0 0.48 9.9 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EMC80332.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_C1 PF00112.18 EMC80333.1 - 6.7e-62 209.2 0.2 9.4e-62 208.7 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.6 EMC80333.1 - 9.7e-39 132.1 0.3 1.7e-38 131.3 0.2 1.3 1 0 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EMC80333.1 - 0.0004 19.0 0.6 0.0031 16.0 0.0 2.4 2 1 1 3 3 3 1 Peptidase C1-like family Propeptide_C1 PF08127.8 EMC80333.1 - 0.013 15.0 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide 7tm_3 PF00003.17 EMC80334.1 - 9.7e-74 247.6 25.0 1.4e-73 247.1 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 EMC80334.1 - 1.1e-46 159.2 0.0 1.8e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region GluR_Homer-bdg PF10606.4 EMC80334.1 - 1.3e-24 85.8 12.1 4.7e-24 84.0 8.4 2.1 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.9 EMC80334.1 - 1.7e-18 66.0 12.7 3.3e-18 65.1 8.8 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 EMC80334.1 - 0.0016 17.8 0.0 0.005 16.2 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein ANF_receptor PF01094.23 EMC80335.1 - 1e-18 67.2 0.0 1.2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NAD_binding_6 PF08030.7 EMC80336.1 - 9.8e-22 77.5 0.0 2.6e-20 72.9 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC80336.1 - 8.5e-19 67.8 4.2 8.5e-19 67.8 2.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMC80336.1 - 2e-15 56.5 0.0 4.3e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMC80336.1 - 0.0088 16.5 0.0 0.063 13.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cytochrom_B_N PF00033.14 EMC80336.1 - 0.036 13.4 1.5 0.56 9.5 0.0 2.5 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB FAD_binding_6 PF00970.19 EMC80336.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ni_hydr_CYTB PF01292.15 EMC80336.1 - 2 7.7 8.5 2.2 7.6 0.1 2.4 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 TFR_dimer PF04253.10 EMC80338.1 - 1.7e-40 137.4 0.1 3.7e-40 136.3 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMC80338.1 - 3e-15 56.4 0.0 6.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMC80338.1 - 6.5e-13 48.2 0.0 1.7e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 PA domain TFR_dimer PF04253.10 EMC80339.1 - 9e-42 141.5 0.0 2.7e-41 140.0 0.0 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMC80339.1 - 5.2e-16 58.8 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMC80339.1 - 3.3e-11 42.7 0.1 7.9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 PA domain IQ-like PF15157.1 EMC80339.1 - 0.0018 18.4 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 IQ-like Nicastrin PF05450.10 EMC80339.1 - 0.17 11.1 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Nicastrin CHORD PF04968.7 EMC80340.1 - 4.4e-57 190.2 17.1 2.8e-28 97.9 4.2 2.6 2 0 0 2 2 2 2 CHORD CS PF04969.11 EMC80340.1 - 5.2e-14 52.5 0.4 1.7e-13 50.8 0.3 2.0 1 1 0 1 1 1 1 CS domain DUF2733 PF10813.3 EMC80340.1 - 0.048 13.2 5.9 2 8.0 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) RhoGAP PF00620.22 EMC80341.1 - 8.5e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1072 PF06380.6 EMC80341.1 - 0.027 14.1 0.3 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Cadherin PF00028.12 EMC80343.1 - 0 1590.4 79.3 1e-22 80.1 0.0 34.7 34 0 0 34 34 34 34 Cadherin domain Laminin_G_2 PF02210.19 EMC80343.1 - 7.2e-23 81.0 1.1 7.7e-22 77.6 0.1 3.0 3 0 0 3 3 3 1 Laminin G domain Cadherin_2 PF08266.7 EMC80343.1 - 3.7e-22 77.6 0.0 1.2 8.7 0.0 16.8 19 0 0 19 19 19 4 Cadherin-like Laminin_G_1 PF00054.18 EMC80343.1 - 3.3e-17 62.7 0.0 1.3e-16 60.8 0.0 2.2 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 EMC80343.1 - 3.5e-10 39.6 60.6 0.0013 18.6 7.5 4.5 4 0 0 4 4 4 4 EGF-like domain EGF_CA PF07645.10 EMC80343.1 - 4e-05 23.4 10.6 4e-05 23.4 7.4 4.3 3 1 1 4 4 4 1 Calcium-binding EGF domain MLANA PF14991.1 EMC80343.1 - 0.0024 17.8 0.0 0.0086 16.0 0.0 1.9 1 0 0 1 1 1 1 Protein melan-A 7tm_1 PF00001.16 EMC80344.1 - 6.3e-51 172.9 25.8 7.4e-51 172.7 17.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC80344.1 - 2e-09 36.9 24.7 3e-09 36.3 17.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 EMC80344.1 - 2e-08 33.7 21.4 2.5e-08 33.3 14.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Aa_trans PF01490.13 EMC80345.1 - 6e-11 41.4 1.6 7.6e-11 41.1 1.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pex14_N PF04695.8 EMC80345.1 - 0.096 12.7 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aa_trans PF01490.13 EMC80346.1 - 3.9e-65 219.9 11.8 4.7e-65 219.6 8.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EMC80346.1 - 0.0013 17.4 13.3 0.0013 17.4 4.2 2.4 2 1 0 2 2 2 2 Spore germination protein RhoGAP PF00620.22 EMC80347.1 - 2.6e-20 72.5 0.0 1.2e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain NYD-SP12_N PF15015.1 EMC80348.1 - 9.9e-178 591.9 0.1 1.2e-177 591.6 0.0 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_11 PF13414.1 EMC80348.1 - 0.04 13.5 0.3 0.094 12.3 0.2 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 EMC80348.1 - 0.057 13.0 0.1 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGEF PF00621.15 EMC80349.1 - 1.1e-44 152.4 0.6 3.3e-44 150.9 0.4 1.8 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.2 EMC80349.1 - 7.9e-23 80.0 0.2 4.8e-17 61.5 0.1 2.6 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.21 EMC80349.1 - 3.1e-15 56.0 0.1 2.2e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Abhydrolase_3 PF07859.8 EMC80350.1 - 5.7e-54 182.8 0.1 9e-39 133.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EMC80350.1 - 3.4e-07 29.2 0.0 5.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EMC80350.1 - 2e-06 26.8 0.1 0.00018 20.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EMC80350.1 - 3.9e-05 23.4 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC80350.1 - 0.00019 20.7 0.0 0.00066 18.9 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EMC80350.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PuR_N PF09182.5 EMC80350.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal AXE1 PF05448.7 EMC80350.1 - 0.065 11.7 0.0 0.098 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TNF PF00229.13 EMC80351.1 - 2.5e-35 120.8 0.1 3.8e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 EMC80351.1 - 0.12 12.4 0.3 0.72 9.8 0.2 2.1 1 1 0 1 1 1 0 C1q domain 7tm_1 PF00001.16 EMC80352.1 - 2.5e-52 177.5 17.0 3.1e-52 177.2 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC80352.1 - 3e-09 36.4 19.3 6.1e-09 35.4 13.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 EMC80352.1 - 0.00038 19.7 19.1 0.0007 18.8 13.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-LITAF-like PF10601.4 EMC80352.1 - 0.039 13.7 5.1 15 5.5 0.2 3.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain CD34_antigen PF06365.7 EMC80352.1 - 0.14 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 CD34/Podocalyxin family 7TM_GPCR_Srx PF10328.4 EMC80352.1 - 0.53 9.3 21.6 0.064 12.3 10.5 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx FA_desaturase PF00487.19 EMC80352.1 - 3.1 7.1 5.6 2.1 7.7 0.5 2.2 1 1 1 2 2 2 0 Fatty acid desaturase fn3 PF00041.16 EMC80353.1 - 2.3e-98 322.4 0.4 8.8e-11 41.7 0.0 9.9 9 1 0 9 9 9 9 Fibronectin type III domain Interfer-bind PF09294.5 EMC80353.1 - 5e-13 49.0 8.7 0.92 9.5 0.0 8.1 8 0 0 8 8 8 5 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 EMC80353.1 - 1.1e-06 28.4 0.1 4.4 7.1 0.0 6.4 8 0 0 8 8 8 3 SusE outer membrane protein PX PF00787.19 EMC80354.1 - 3.3e-21 75.1 3.5 1e-20 73.6 2.4 1.9 1 0 0 1 1 1 1 PX domain PLDc PF00614.17 EMC80354.1 - 5.5e-16 57.7 1.8 2.3e-08 33.5 0.1 3.3 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EMC80354.1 - 2.6e-13 49.8 0.3 1.3e-08 34.6 0.1 3.0 2 1 0 2 2 2 2 PLD-like domain PH PF00169.24 EMC80354.1 - 1.1e-06 28.7 0.0 3.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF3785 PF12653.2 EMC80354.1 - 0.018 14.9 0.3 0.046 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Pkinase PF00069.20 EMC80355.1 - 5.3e-67 225.7 0.0 5.3e-67 225.7 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain CNH PF00780.17 EMC80355.1 - 1.3e-59 201.8 0.0 2e-59 201.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 EMC80355.1 - 1.1e-48 165.5 0.0 2.1e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC80355.1 - 1.6e-05 24.0 0.0 4.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Sugar_tr PF00083.19 EMC80356.1 - 9.3e-153 509.0 20.9 1.2e-152 508.6 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC80356.1 - 7.1e-20 71.0 37.2 1e-16 60.6 17.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC80356.1 - 1.1e-10 40.5 26.5 6.2e-08 31.4 5.3 3.3 1 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EMC80356.1 - 0.03 14.0 5.8 1.1 9.0 0.1 3.1 2 0 0 2 2 2 0 MFS_1 like family TM231 PF10149.4 EMC80356.1 - 6.9 5.5 6.8 0.26 10.2 0.5 1.7 2 0 0 2 2 2 0 Transmembrane protein 231 eIF-5a PF01287.15 EMC80357.1 - 6.8e-26 90.0 0.1 9.4e-26 89.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EMC80357.1 - 0.0017 18.0 0.2 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EMC80357.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Ribosomal_L22e PF01776.12 EMC80358.1 - 3.5e-51 171.9 3.8 4.2e-51 171.6 2.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AA_permease_2 PF13520.1 EMC80359.1 - 2.6e-45 154.7 57.1 1.8e-44 151.9 26.3 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 EMC80359.1 - 1.3e-37 129.3 38.8 1.3e-37 129.3 26.9 2.4 2 1 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.1 EMC80359.1 - 2.4e-20 72.1 9.8 2.4e-20 72.1 6.8 4.7 5 0 0 5 5 5 1 C-terminus of AA_permease DUF1469 PF07332.6 EMC80359.1 - 0.026 14.2 1.1 0.026 14.2 0.8 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1469) PMP22_Claudin PF00822.15 EMC80360.1 - 8.9e-20 70.9 10.6 1.2e-19 70.5 7.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC80360.1 - 3.6e-08 33.2 6.0 3.6e-08 33.2 4.1 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EMC80360.1 - 1.6 7.9 5.2 1 8.5 0.4 2.2 2 0 0 2 2 2 0 Clc-like DUF4233 PF14017.1 EMC80360.1 - 3.8 7.4 7.9 0.22 11.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) DUF4131 PF13567.1 EMC80360.1 - 6.2 6.1 5.7 2 7.7 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) c-SKI_SMAD_bind PF08782.5 EMC80361.1 - 4.6e-44 148.4 3.2 4.6e-44 148.4 2.2 2.3 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Ski_Sno PF02437.12 EMC80361.1 - 1.2e-43 147.2 1.1 2.9e-43 146.0 0.7 1.6 1 0 0 1 1 1 1 SKI/SNO/DAC family DUF489 PF04356.7 EMC80361.1 - 0.46 10.0 10.0 0.4 10.2 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Pkinase PF00069.20 EMC80362.1 - 2.3e-64 217.0 0.0 3e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80362.1 - 2.2e-34 118.7 0.0 3.3e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EMC80362.1 - 4.3e-14 51.9 9.9 8.4e-14 51.0 6.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.19 EMC80362.1 - 1.4e-10 40.6 0.0 4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.19 EMC80362.1 - 8.4e-07 29.4 1.1 1.8e-06 28.3 0.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC80362.1 - 3.1e-06 26.3 0.0 4.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC80362.1 - 0.01 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC80362.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_3 PF07649.7 EMC80362.1 - 0.057 13.4 1.5 0.18 11.8 1.1 1.8 1 0 0 1 1 1 0 C1-like domain SAM_1 PF00536.25 EMC80363.1 - 2.4e-15 56.4 0.0 4.1e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC80363.1 - 1.2e-09 37.8 0.0 2.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-FCS PF06467.9 EMC80363.1 - 0.0019 17.7 3.3 0.0055 16.3 2.3 1.8 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif SAM_PNT PF02198.11 EMC80363.1 - 0.0049 16.6 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain LRR_8 PF13855.1 EMC80365.1 - 8.5e-73 240.0 29.7 6.1e-16 57.9 0.2 4.5 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EMC80365.1 - 1.6e-29 100.9 24.7 1.5e-07 30.8 0.1 5.9 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC80365.1 - 1.6e-19 66.9 8.4 0.047 13.7 0.0 9.2 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 EMC80365.1 - 7.9e-12 43.3 21.6 0.37 11.1 0.1 9.2 9 0 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 EMC80365.1 - 3.5e-08 32.6 9.5 8.1 6.8 0.0 8.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_5 PF13306.1 EMC80365.1 - 2.2e-05 24.1 0.0 0.037 13.7 0.0 2.3 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC80365.1 - 9.7e-05 21.9 2.1 0.016 14.7 0.3 3.0 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.13 EMC80365.1 - 0.00072 18.9 1.5 0.0018 17.7 1.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 EMC80366.1 - 1.8e-77 255.0 92.7 5.7e-14 51.6 2.8 8.3 1 1 8 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 EMC80366.1 - 6.5e-34 114.9 62.5 8.3e-07 28.4 2.1 9.2 3 1 8 12 12 12 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC80366.1 - 1.2e-30 105.8 0.1 2.1e-09 37.1 0.0 3.7 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC80366.1 - 2.9e-22 75.2 62.4 0.029 14.3 0.2 14.9 15 1 0 15 15 15 11 Leucine Rich Repeat LRR_9 PF14580.1 EMC80366.1 - 8.7e-11 41.6 19.9 0.00037 20.1 1.1 5.3 1 1 5 6 6 6 4 Leucine-rich repeat LRR_7 PF13504.1 EMC80366.1 - 0.0032 17.4 60.4 4.2 7.9 0.1 14.5 15 0 0 15 15 15 3 Leucine rich repeat DNA_ligase_IV PF11411.3 EMC80366.1 - 0.084 12.6 0.1 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 DNA ligase IV LRR_6 PF13516.1 EMC80366.1 - 0.16 12.1 31.8 6.5 7.1 0.0 10.1 10 0 0 10 10 10 0 Leucine Rich repeat CECR6_TMEM121 PF14997.1 EMC80367.1 - 1.3e-61 207.6 12.2 2.3e-61 206.8 8.4 1.4 1 0 0 1 1 1 1 CECR6/TMEM121 family EIID-AGA PF03613.9 EMC80367.1 - 0.00023 20.2 2.5 0.00036 19.5 1.7 1.3 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component Kelch_6 PF13964.1 EMC80368.1 - 1.1e-46 155.1 10.9 1.9e-10 40.4 0.1 6.2 5 1 1 6 6 6 5 Kelch motif DUF947 PF06102.7 EMC80368.1 - 4e-43 147.1 29.7 8e-43 146.1 20.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF947) Kelch_2 PF07646.10 EMC80368.1 - 4.4e-41 137.1 10.6 4.8e-07 29.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EMC80368.1 - 4.2e-38 128.6 7.4 1.1e-06 28.0 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EMC80368.1 - 4.3e-36 122.2 10.3 1.5e-08 34.5 0.2 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC80368.1 - 7.4e-36 121.6 19.3 5.4e-08 32.4 0.3 7.6 6 3 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC80368.1 - 1.7e-34 117.2 10.8 6.2e-07 29.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Rax2 PF12768.2 EMC80368.1 - 0.053 12.7 0.0 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Cortical protein marker for cell polarity B56 PF01603.15 EMC80369.1 - 1.7e-170 567.1 7.8 1.9e-170 566.9 5.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.20 EMC80370.1 - 2.5e-06 26.8 0.1 0.014 14.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Abhydrolase_5 PF12695.2 EMC80371.1 - 9e-19 67.6 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC80371.1 - 3e-17 63.2 0.1 9.2e-17 61.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC80371.1 - 3e-09 36.8 0.2 3.3e-06 26.8 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMC80371.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMC80371.1 - 0.00025 20.8 0.3 0.00047 19.9 0.2 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EMC80371.1 - 0.002 17.3 0.0 0.0059 15.8 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMC80371.1 - 0.008 15.6 0.0 0.036 13.4 0.0 2.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EMC80371.1 - 0.0091 16.2 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.13 EMC80371.1 - 0.031 13.6 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 EMC80371.1 - 0.05 12.8 0.1 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase DUF2424 PF10340.4 EMC80371.1 - 0.11 11.0 0.0 0.24 10.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Phosphorylase PF00343.15 EMC80372.1 - 0 1200.0 0.0 0 1199.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase GDA1_CD39 PF01150.12 EMC80373.1 - 2.9e-73 246.8 0.0 5e-72 242.7 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EMC80373.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Homeobox PF00046.24 EMC80374.1 - 3.4e-24 84.2 2.8 6.3e-24 83.3 1.9 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC80374.1 - 0.0024 17.5 0.5 0.0075 15.9 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain AAA PF00004.24 EMC80375.1 - 5.6e-62 207.7 0.0 6.3e-45 152.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMC80375.1 - 1.2e-07 31.3 0.1 0.0016 18.1 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EMC80375.1 - 1.2e-07 31.8 0.3 0.0067 16.5 0.1 3.7 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 EMC80375.1 - 3.3e-07 30.4 6.8 0.0073 16.3 0.2 3.5 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EMC80375.1 - 1.5e-06 27.9 0.2 0.0057 16.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMC80375.1 - 1.7e-05 25.6 0.0 0.035 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EMC80375.1 - 3.4e-05 23.0 3.5 0.012 14.7 0.1 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMC80375.1 - 0.00012 21.9 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EMC80375.1 - 0.00031 20.7 0.0 0.51 10.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMC80375.1 - 0.00077 18.9 0.4 0.0063 15.9 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EMC80375.1 - 0.00081 19.5 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 EMC80375.1 - 0.00098 18.2 0.0 0.006 15.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMC80375.1 - 0.0011 18.9 0.0 0.07 13.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EMC80375.1 - 0.0042 16.5 0.0 2.5 7.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.8 EMC80375.1 - 0.0048 15.6 0.2 0.042 12.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EMC80375.1 - 0.0049 16.2 2.0 0.12 11.7 0.2 2.9 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.8 EMC80375.1 - 0.0074 15.2 0.0 0.31 9.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 EMC80375.1 - 0.0086 15.7 0.3 1.6 8.4 0.1 3.1 3 0 0 3 3 3 1 NACHT domain T2SE PF00437.15 EMC80375.1 - 0.0096 14.8 0.0 3.5 6.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 EMC80375.1 - 0.018 15.3 0.1 0.86 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EMC80375.1 - 0.02 14.5 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMC80375.1 - 0.022 14.2 1.2 1.3 8.6 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EMC80375.1 - 0.034 13.7 0.2 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EMC80375.1 - 0.035 13.6 0.9 0.1 12.1 0.7 1.7 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.5 EMC80375.1 - 0.045 13.6 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 EMC80375.1 - 0.051 12.4 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EMC80375.1 - 0.06 12.9 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EMC80375.1 - 0.063 12.4 0.4 0.27 10.4 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 EMC80375.1 - 0.079 12.9 0.2 0.26 11.2 0.0 1.9 3 0 0 3 3 1 0 AAA domain NTPase_1 PF03266.10 EMC80375.1 - 0.08 12.6 0.2 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 EMC80375.1 - 0.082 11.9 0.0 7 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EMC80375.1 - 0.11 11.9 0.1 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EMC80375.1 - 0.12 12.2 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMC80375.1 - 0.15 10.8 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 EMC80375.1 - 0.18 11.2 0.1 13 5.0 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EMC80375.1 - 0.19 12.0 0.0 19 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Methyltransf_18 PF12847.2 EMC80376.1 - 8.3e-10 39.2 0.0 1.4e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC80376.1 - 2.9e-09 36.6 0.0 4.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC80376.1 - 1.8e-07 31.5 0.0 3.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC80376.1 - 2.9e-07 30.3 0.0 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC80376.1 - 2.4e-06 27.9 0.0 4.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC80376.1 - 6.7e-05 23.1 0.0 0.00017 21.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF3456 PF11938.3 EMC80377.1 - 9.6e-43 145.7 2.8 9.6e-43 145.7 2.0 1.8 2 0 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP Frigida PF07899.6 EMC80377.1 - 0.013 14.3 1.8 0.015 14.0 0.8 1.4 2 0 0 2 2 2 0 Frigida-like protein BRF1 PF07741.8 EMC80377.1 - 0.014 15.5 1.2 0.026 14.7 0.8 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PTCRA PF15028.1 EMC80378.1 - 7.9e-17 61.2 0.4 8.7e-17 61.1 0.3 1.0 1 0 0 1 1 1 1 Pre-T-cell antigen receptor C1-set PF07654.10 EMC80378.1 - 0.0099 15.8 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Protein_K PF12283.3 EMC80378.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage protein K RNA_pol_Rpb2_6 PF00562.23 EMC80379.1 - 3.7e-103 345.2 0.0 5.7e-103 344.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.11 EMC80379.1 - 6.1e-24 83.5 0.0 1.5e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.10 EMC80379.1 - 2.7e-19 68.9 0.1 3.9e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EMC80379.1 - 5.6e-19 68.1 0.0 1.2e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 EMC80379.1 - 6.2e-19 67.7 0.0 1.4e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EMC80379.1 - 2.4e-11 43.4 0.0 3.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Sugar_tr PF00083.19 EMC80380.1 - 1.1e-33 116.5 20.0 1.4e-33 116.1 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC80380.1 - 6.6e-31 107.3 22.5 8.5e-31 106.9 15.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMC80380.1 - 0.19 9.8 9.9 0.023 12.8 3.5 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Ig_2 PF13895.1 EMC80381.1 - 4.8e-15 55.4 0.5 2.7e-06 27.4 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC80381.1 - 2.7e-09 37.3 0.4 0.0022 18.4 0.3 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC80381.1 - 6.3e-06 25.9 0.1 0.015 15.0 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain ICAM_N PF03921.9 EMC80381.1 - 1.7e-05 24.2 0.4 0.00027 20.3 0.0 2.1 2 0 0 2 2 2 1 Intercellular adhesion molecule (ICAM), N-terminal domain ig PF00047.20 EMC80381.1 - 0.00011 22.2 3.5 0.075 13.1 0.7 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC80381.1 - 0.00024 20.9 3.0 0.12 12.3 0.0 3.4 2 2 1 3 3 3 2 Immunoglobulin V-set domain MBT PF02820.13 EMC80382.1 - 1.4e-95 313.3 3.3 4.8e-32 109.6 0.0 3.4 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.13 EMC80382.1 - 6.6e-18 64.1 20.3 3.4e-14 52.2 6.3 2.7 1 1 1 2 2 2 2 Zinc finger, C2HC type SAM_1 PF00536.25 EMC80382.1 - 2.4e-12 46.8 0.0 4.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF329 PF03884.9 EMC80382.1 - 0.0088 15.5 0.5 0.031 13.8 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF329) Ste50p-SAM PF09235.5 EMC80382.1 - 0.07 13.1 0.1 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif 4_1_CTD PF05902.8 EMC80384.1 - 7e-44 148.5 3.7 7e-44 148.5 2.6 3.0 2 1 1 3 3 3 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 EMC80384.1 - 4.9e-19 67.7 1.6 4.9e-19 67.7 1.1 2.4 2 0 0 2 2 2 1 SAB domain AAR2 PF05282.6 EMC80385.1 - 5e-49 167.1 0.2 6e-49 166.8 0.1 1.0 1 0 0 1 1 1 1 AAR2 protein Alginate_lyase PF05426.7 EMC80385.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Alginate lyase GKAP PF03359.8 EMC80386.1 - 2.1e-117 392.7 15.5 2.1e-117 392.7 10.7 3.5 4 0 0 4 4 4 1 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.6 EMC80387.1 - 0.0021 17.7 2.7 0.0033 17.0 1.9 1.3 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_1 PF00036.27 EMC80388.1 - 1.5e-16 58.3 9.7 5e-08 31.6 1.1 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EMC80388.1 - 3.1e-13 49.6 8.9 2.6e-09 37.1 1.3 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC80388.1 - 1.5e-12 46.2 8.0 6.3e-08 31.8 0.6 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EMC80388.1 - 1.3e-10 40.7 8.7 1.3e-05 24.6 0.1 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC80388.1 - 4.5e-06 25.7 3.0 1.4e-05 24.2 0.9 2.5 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 EMC80388.1 - 0.00035 20.1 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 EMC80388.1 - 0.0043 16.9 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EMC80388.1 - 0.096 12.7 0.7 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1880 PF08976.6 EMC80388.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) Rab5ip PF07019.7 EMC80389.1 - 7.5e-28 96.4 9.1 8.5e-28 96.3 6.3 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF441 PF04284.8 EMC80389.1 - 0.084 12.7 1.9 0.13 12.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF441) Clc-like PF07062.7 EMC80389.1 - 0.089 12.0 3.5 0.11 11.7 2.4 1.0 1 0 0 1 1 1 0 Clc-like DUF2244 PF10003.4 EMC80389.1 - 0.23 10.8 4.5 0.17 11.2 0.5 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Yip1 PF04893.12 EMC80389.1 - 0.56 9.6 9.8 3.5 7.0 6.8 1.9 1 1 0 1 1 1 0 Yip1 domain Nucleic_acid_bd PF13820.1 EMC80390.1 - 1.1e-45 154.9 0.0 2.5e-45 153.7 0.0 1.7 1 0 0 1 1 1 1 Putative nucleic acid-binding region MSP1_C PF07462.6 EMC80390.1 - 2.2 6.5 9.8 5.3 5.3 6.8 1.6 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DOR PF14839.1 EMC80392.1 - 4.8e-33 114.7 1.6 6.6e-31 107.7 1.1 2.3 1 1 0 1 1 1 1 DOR family PIG-U PF06728.8 EMC80393.1 - 1.2e-105 353.5 48.3 1.3e-105 353.3 33.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U TLD PF07534.11 EMC80394.1 - 1e-35 122.7 0.0 1.2e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 TLD RB_A PF01858.12 EMC80395.1 - 1.1e-80 269.9 0.2 1.1e-80 269.9 0.1 1.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.15 EMC80395.1 - 1.8e-58 195.8 0.2 1.8e-58 195.8 0.1 2.0 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.3 EMC80395.1 - 5.3e-45 152.1 0.1 1.5e-44 150.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) Rb_C PF08934.5 EMC80395.1 - 6.1e-07 29.2 0.4 1.8e-06 27.6 0.3 1.8 1 0 0 1 1 1 1 Rb C-terminal domain eIF-3c_N PF05470.7 EMC80395.1 - 0.95 7.4 8.2 2.2 6.2 4.2 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SNF2_N PF00176.18 EMC80396.1 - 1.8e-68 230.5 1.4 2.7e-68 229.9 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EMC80396.1 - 3.4e-25 87.4 3.6 4.3e-13 48.7 0.7 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EMC80396.1 - 7.9e-13 48.0 0.0 2.3e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRK PF07533.11 EMC80396.1 - 7.7e-09 34.8 0.1 1.2e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 BRK domain ResIII PF04851.10 EMC80396.1 - 2.1e-06 27.7 0.0 9.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC80396.1 - 7.8e-05 22.2 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 EMC80396.1 - 0.019 14.7 3.7 17 5.0 0.0 4.0 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain Collagen PF01391.13 EMC80397.1 - 2.8e-17 62.0 32.0 9.7e-09 34.6 10.5 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PID PF00640.18 EMC80398.1 - 6.3e-48 162.3 0.0 1.1e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 EMC80398.1 - 2.6e-17 62.4 0.0 8.5e-17 60.7 0.0 1.9 2 0 0 2 2 2 1 SH2 domain PTB PF08416.8 EMC80398.1 - 0.041 13.7 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotyrosine-binding domain 7tm_1 PF00001.16 EMC80399.1 - 5.5e-40 137.1 24.6 7e-40 136.7 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC80399.1 - 9e-10 38.1 24.7 1.1e-09 37.8 17.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ODV-E18 PF10717.4 EMC80399.1 - 0.73 9.3 3.8 1.3 8.5 2.1 1.8 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Thioredoxin_8 PF13905.1 EMC80400.1 - 7.6e-29 99.6 0.0 1.1e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 EMC80400.1 - 5.6e-08 32.4 0.1 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 EMC80400.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 EMC80400.1 - 4.6e-06 26.7 0.0 6.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EMC80400.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family NADH_4Fe-4S PF10589.4 EMC80400.1 - 0.052 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Thioredoxin_9 PF14595.1 EMC80400.1 - 0.066 12.7 0.0 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin TrbC_Ftype PF09673.5 EMC80400.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Spin-Ssty PF02513.12 EMC80401.1 - 2.2e-77 254.4 6.7 1.3e-27 95.0 0.1 3.2 3 0 0 3 3 3 3 Spin/Ssty Family MFS_1 PF07690.11 EMC80402.1 - 2.2e-34 118.7 38.6 1.4e-33 116.0 25.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Myosin_tail_1 PF01576.14 EMC80403.1 - 3.8e-289 961.2 185.3 4.3e-289 961.0 128.4 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.16 EMC80403.1 - 3.7e-07 29.9 154.9 0.0023 17.4 41.3 5.8 1 1 3 4 4 4 3 Intermediate filament protein Reo_sigmaC PF04582.7 EMC80403.1 - 1.2e-06 28.0 50.2 0.00085 18.6 2.3 7.0 1 1 8 9 9 9 7 Reovirus sigma C capsid protein WEMBL PF05701.6 EMC80403.1 - 0.00016 20.3 70.6 0.00016 20.3 48.9 5.0 1 1 3 4 4 3 1 Weak chloroplast movement under blue light DUF869 PF05911.6 EMC80403.1 - 0.00096 17.5 9.8 0.00096 17.5 6.8 6.3 1 1 4 5 5 5 2 Plant protein of unknown function (DUF869) DUF1664 PF07889.7 EMC80403.1 - 0.009 15.8 4.4 0.009 15.8 3.0 9.2 3 1 7 10 10 10 5 Protein of unknown function (DUF1664) IncA PF04156.9 EMC80403.1 - 0.12 11.9 167.9 0.52 9.8 11.4 9.0 1 1 6 7 7 7 0 IncA protein AAA_13 PF13166.1 EMC80403.1 - 0.13 10.7 128.7 0.016 13.6 20.5 5.1 1 1 4 5 5 5 0 AAA domain Bacillus_HBL PF05791.6 EMC80403.1 - 0.14 11.5 102.1 0.026 13.8 6.8 9.7 2 2 6 9 9 9 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.7 EMC80403.1 - 0.21 11.3 169.3 0.82 9.4 12.3 8.9 3 2 4 7 7 7 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 EMC80403.1 - 1.2 9.2 109.0 0.054 13.6 7.2 8.2 2 2 6 9 9 9 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EMC80403.1 - 4.4 7.0 104.4 0.039 13.6 3.8 9.3 1 1 8 9 9 8 0 Laminin Domain II CALCOCO1 PF07888.6 EMC80403.1 - 7.2 4.7 139.7 0.092 11.0 15.3 5.2 1 1 3 4 4 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like PDZ PF00595.19 EMC80404.1 - 6.9e-08 32.5 0.7 1e-07 32.0 0.4 1.3 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2562 PF10814.3 EMC80404.1 - 0.066 13.1 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) PDZ PF00595.19 EMC80405.1 - 3.2e-18 65.6 0.5 4.7e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC80405.1 - 0.00032 20.5 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GPP34 PF05719.6 EMC80406.1 - 1.3e-52 178.9 0.6 1.5e-52 178.6 0.4 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.8 EMC80406.1 - 0.02 14.3 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Myotub-related PF06602.9 EMC80407.1 - 2.6e-54 184.3 6.6 2.2e-51 174.7 3.1 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.3 EMC80407.1 - 2.9e-29 101.7 0.0 5.7e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein PC4 PF02229.11 EMC80408.1 - 1.2e-23 82.0 0.3 2.3e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.6 EMC80408.1 - 0.016 14.6 0.2 0.023 14.0 0.2 1.3 1 0 0 1 1 1 0 QLQ SR-25 PF10500.4 EMC80408.1 - 0.086 12.2 11.1 0.12 11.7 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.7 EMC80408.1 - 0.81 9.5 4.5 0.98 9.2 3.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4557 PF15101.1 EMC80408.1 - 1.2 8.9 5.2 3.4 7.4 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) ANF_receptor PF01094.23 EMC80409.1 - 1.9e-39 135.4 0.7 2.4e-39 135.1 0.5 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EMC80409.1 - 0.0073 15.6 0.0 0.024 13.9 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein DUF2555 PF10742.4 EMC80409.1 - 0.06 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) tRNA-synt_2b PF00587.20 EMC80410.1 - 1.9e-46 157.7 1.3 2.4e-46 157.4 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC80410.1 - 2.8e-20 72.0 0.1 6.4e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EMC80410.1 - 1.5e-18 66.3 0.1 1.5e-17 63.1 0.0 2.3 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 EMC80410.1 - 1.8e-12 46.9 0.1 4.2e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain START PF01852.14 EMC80412.1 - 2.3e-41 141.4 0.3 3.9e-41 140.6 0.2 1.3 1 0 0 1 1 1 1 START domain RhoGAP PF00620.22 EMC80412.1 - 1.4e-36 125.4 0.7 2.7e-36 124.4 0.5 1.5 1 0 0 1 1 1 1 RhoGAP domain SAM_2 PF07647.12 EMC80412.1 - 0.0027 17.5 1.0 0.0092 15.8 0.0 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Glyco_hydro_1 PF00232.13 EMC80413.1 - 6.6e-165 548.7 15.3 2.8e-76 256.5 3.9 4.0 2 2 1 3 3 3 3 Glycosyl hydrolase family 1 HEAT_2 PF13646.1 EMC80415.1 - 8.6e-06 25.9 3.0 2 8.7 0.0 5.8 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.17 EMC80415.1 - 0.00013 21.7 4.2 15 6.0 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 EMC80415.1 - 0.97 9.2 19.0 0.28 11.0 0.6 5.7 4 2 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EMC80415.1 - 1.6 9.3 4.2 2e+02 2.6 0.0 5.3 7 0 0 7 7 7 0 HEAT-like repeat AAA_33 PF13671.1 EMC80416.1 - 9.2e-16 58.0 0.0 1.7e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC80416.1 - 2.7e-07 29.9 0.0 6.4e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EMC80416.1 - 1.9e-05 25.4 0.0 5.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC80416.1 - 8.7e-05 22.8 0.5 0.00082 19.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EMC80416.1 - 0.00021 20.5 0.5 0.00075 18.7 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 EMC80416.1 - 0.0045 17.2 0.3 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EMC80416.1 - 0.05 13.7 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMC80416.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain EIIBC-GUT_N PF03612.9 EMC80417.1 - 0.18 11.3 2.1 0.22 11.1 0.1 1.8 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus AAA_33 PF13671.1 EMC80418.1 - 6.3e-10 39.0 0.2 9.2e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain BRCA-2_helical PF09169.5 EMC80419.1 - 1.5e-97 324.8 0.2 7.6e-97 322.5 0.0 2.4 2 0 0 2 2 2 1 BRCA2, helical BRCA-2_OB3 PF09104.5 EMC80419.1 - 2.8e-63 212.0 0.2 2.8e-63 212.0 0.1 2.2 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 PF00634.13 EMC80419.1 - 4.6e-47 156.8 26.3 2.5e-11 42.5 0.7 7.1 6 0 0 6 6 6 6 BRCA2 repeat BRCA-2_OB1 PF09103.5 EMC80419.1 - 4.3e-42 142.5 0.0 1.1e-41 141.2 0.0 1.8 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tower PF09121.5 EMC80419.1 - 1.1e-22 79.6 4.3 2.7e-22 78.4 3.0 1.7 1 0 0 1 1 1 1 Tower zf-3CxxC PF13695.1 EMC80420.1 - 1.1e-17 64.0 18.8 2.2e-17 63.0 13.1 1.5 1 0 0 1 1 1 1 Zinc-binding domain MOR2-PAG1_N PF14222.1 EMC80421.1 - 1.6e-170 568.4 4.2 2.8e-170 567.6 2.9 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EMC80421.1 - 1.3e-74 251.3 13.8 2.5e-74 250.3 7.8 2.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EMC80421.1 - 5.6e-29 100.4 5.0 1.5e-09 36.1 0.0 5.8 6 0 0 6 6 6 5 Cell morphogenesis central region MAPEG PF01124.13 EMC80422.1 - 1e-08 34.8 0.3 1.3e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 MAPEG family Ndr PF03096.9 EMC80422.1 - 0.04 12.3 0.0 0.051 12.0 0.0 1.1 1 0 0 1 1 1 0 Ndr family DUF4650 PF15509.1 EMC80423.1 - 4.2e-143 478.0 26.2 9.2e-126 420.7 17.7 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4650) Peptidase_C98 PF15499.1 EMC80423.1 - 1.3e-136 454.3 10.3 2.9e-136 453.2 7.1 1.6 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase HMG_box_2 PF09011.5 EMC80424.1 - 4.7e-41 138.9 12.9 1.6e-26 92.4 5.5 2.7 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.14 EMC80424.1 - 2.5e-40 136.5 12.2 1.7e-25 89.0 0.2 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.1 EMC80424.1 - 4.3 7.1 22.3 0.12 12.2 2.4 2.7 2 1 0 2 2 2 0 HMG (high mobility group) box 5 Sof1 PF04158.9 EMC80424.1 - 4.6 7.3 21.3 0.14 12.1 8.5 2.5 2 1 0 2 2 2 0 Sof1-like domain AAA PF00004.24 EMC80425.1 - 4.1e-40 137.0 0.0 1e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMC80425.1 - 2e-08 33.9 0.2 1.1e-07 31.6 0.0 2.3 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 EMC80425.1 - 5.6e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC80425.1 - 1.4e-05 24.2 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMC80425.1 - 2.4e-05 24.3 0.0 4.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMC80425.1 - 0.00025 20.7 0.5 0.0014 18.3 0.2 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMC80425.1 - 0.00026 21.8 0.0 0.0017 19.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EMC80425.1 - 0.00027 19.7 0.0 0.00044 19.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EMC80425.1 - 0.00046 20.3 0.4 0.0046 17.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMC80425.1 - 0.0006 19.0 0.2 0.0013 17.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EMC80425.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EMC80425.1 - 0.0022 18.0 0.1 0.027 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMC80425.1 - 0.0025 17.7 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC80425.1 - 0.0036 17.0 0.1 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EMC80425.1 - 0.0043 16.1 0.0 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EMC80425.1 - 0.012 15.0 0.3 0.23 10.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EMC80425.1 - 0.013 15.1 0.1 0.068 12.8 0.1 2.0 1 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EMC80425.1 - 0.019 14.9 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMC80425.1 - 0.026 13.6 0.2 2.1 7.4 0.1 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EMC80425.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.16 EMC80425.1 - 0.046 13.1 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase TPR_8 PF13181.1 EMC80425.1 - 0.047 13.4 4.6 0.11 12.3 0.2 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat RNA_helicase PF00910.17 EMC80425.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EMC80425.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC80425.1 - 0.1 12.9 4.4 0.29 11.4 1.2 3.0 2 1 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EMC80425.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EMC80425.1 - 0.19 11.2 0.5 0.37 10.3 0.1 1.7 2 0 0 2 2 1 0 AAA domain Rad60-SLD_2 PF13881.1 EMC80426.1 - 1.4e-31 108.6 0.0 1.6e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMC80426.1 - 0.00031 20.0 0.0 0.00054 19.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Met_gamma_lyase PF06838.6 EMC80426.1 - 0.057 11.6 0.0 0.074 11.3 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase DUF2407 PF10302.4 EMC80426.1 - 0.081 13.1 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AA_permease_2 PF13520.1 EMC80427.1 - 2.8e-54 184.2 26.8 2.8e-54 184.2 18.5 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 EMC80427.1 - 1.9e-43 148.5 26.2 1.9e-43 148.5 18.1 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 EMC80427.1 - 3.5e-25 87.6 9.8 3.5e-25 87.6 6.8 3.9 5 0 0 5 5 5 1 C-terminus of AA_permease NPV_P10 PF05531.7 EMC80428.1 - 1.7 8.9 22.0 0.61 10.3 2.4 4.8 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 EMC80429.1 - 1.2e-15 57.1 28.7 1.2e-15 57.1 19.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3 PF05106.7 EMC80429.1 - 0.004 17.1 0.9 0.019 14.9 0.6 2.2 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) UMP1 PF05348.6 EMC80430.1 - 1.2e-43 148.1 0.1 1.5e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase_Tyr PF07714.12 EMC80431.1 - 4.1e-103 343.9 0.0 6.5e-103 343.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.11 EMC80431.1 - 5.4e-54 180.0 7.1 1.6e-16 59.9 0.0 7.1 6 1 0 6 6 6 6 Immunoglobulin I-set domain Pkinase PF00069.20 EMC80431.1 - 1.3e-45 155.5 0.0 1.6e-31 109.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.1 EMC80431.1 - 3e-45 152.2 5.2 8.2e-10 38.6 0.0 7.6 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 EMC80431.1 - 8.1e-28 96.7 6.0 4.2e-07 30.3 0.0 8.5 8 2 0 8 8 8 5 Immunoglobulin domain ig PF00047.20 EMC80431.1 - 8.2e-19 67.5 6.8 0.00031 20.8 0.0 8.5 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 EMC80431.1 - 8.9e-18 64.2 14.3 0.0016 18.3 0.0 7.8 6 3 0 6 6 6 5 Immunoglobulin V-set domain C1-set PF07654.10 EMC80431.1 - 2.5e-06 27.3 5.5 0.44 10.5 0.0 4.9 5 0 0 5 5 5 3 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC80431.1 - 7.2e-05 22.6 1.1 2.9 7.8 0.0 4.7 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Pkinase PF00069.20 EMC80432.1 - 0.0016 17.6 0.0 0.0043 16.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80433.1 - 2.7e-102 341.2 0.0 3.8e-102 340.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC80433.1 - 6e-48 163.2 0.0 2.7e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.1 EMC80433.1 - 0.00031 20.8 9.0 0.0034 17.4 0.0 4.6 4 1 0 4 4 4 1 Immunoglobulin domain APH PF01636.18 EMC80433.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Homeobox PF00046.24 EMC80434.1 - 1.3e-22 79.1 6.1 2.1e-22 78.4 4.3 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 EMC80435.1 - 1.3e-22 79.0 4.5 1.9e-22 78.5 3.1 1.2 1 0 0 1 1 1 1 Homeobox domain Terminase_5 PF06056.7 EMC80435.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) Phage_terminase PF10668.4 EMC80435.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Phage terminase small subunit HTH_23 PF13384.1 EMC80435.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox_KN PF05920.6 EMC80435.1 - 0.11 12.1 0.2 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF3489 PF11994.3 EMC80436.1 - 0.07 13.0 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) IF3_N PF05198.11 EMC80437.1 - 1.4e-17 63.3 0.0 3.5e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.17 EMC80437.1 - 9.8e-14 50.8 0.7 2.9e-13 49.3 0.5 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain DM4_12 PF07841.8 EMC80437.1 - 0.038 14.3 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 DM4/DM12 family HTH_33 PF13592.1 EMC80437.1 - 0.059 12.9 0.1 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DUF3993 PF13158.1 EMC80437.1 - 0.061 13.1 0.4 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) HTH_32 PF13565.1 EMC80437.1 - 0.21 12.4 1.2 4.8 8.0 0.8 2.6 1 1 0 1 1 1 0 Homeodomain-like domain zf-C2H2 PF00096.21 EMC80438.1 - 3.3e-31 105.7 54.8 1.6e-05 24.9 1.8 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80438.1 - 2e-19 68.3 46.0 0.0022 18.2 0.6 8.3 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC80438.1 - 3.3e-19 68.1 63.3 1.7e-05 24.8 0.4 9.2 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC80438.1 - 1.6e-06 28.0 25.5 0.53 10.4 1.2 7.1 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC80438.1 - 0.00026 21.0 42.8 0.023 14.9 0.1 7.4 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-Di19 PF05605.7 EMC80438.1 - 0.0021 18.1 20.6 0.13 12.4 2.1 5.0 2 2 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding CHORD PF04968.7 EMC80438.1 - 0.025 14.7 39.7 0.56 10.4 2.1 7.0 3 3 5 8 8 8 0 CHORD zf-met PF12874.2 EMC80438.1 - 0.031 14.4 22.2 6.9 7.0 1.0 7.0 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-met2 PF12907.2 EMC80438.1 - 7.6 6.5 16.4 1.1 9.3 1.1 4.1 4 0 0 4 4 4 0 Zinc-binding Ras PF00071.17 EMC80439.1 - 2.7e-31 108.1 0.0 3.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80439.1 - 2e-17 63.7 0.0 3.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC80439.1 - 1.8e-06 27.8 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMC80439.1 - 0.0012 17.9 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AlkA_N PF06029.6 EMC80439.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 AlkA N-terminal domain GTP_EFTU PF00009.22 EMC80439.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMC80439.1 - 0.14 11.9 0.1 5.1 6.8 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Ribosomal_L21e PF01157.13 EMC80440.1 - 1e-44 150.3 6.3 1e-44 150.3 4.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e CLP_protease PF00574.18 EMC80440.1 - 0.11 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Clp protease UCH PF00443.24 EMC80441.1 - 1.1e-70 237.8 3.3 1.2e-70 237.6 2.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC80441.1 - 5.4e-39 134.3 1.4 6.4e-39 134.1 1.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EMC80441.1 - 0.78 8.9 9.9 2.3 7.4 5.1 2.7 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase RVT_1 PF00078.22 EMC80442.1 - 0.095 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.16 EMC80443.1 - 1e-38 132.9 21.3 1.3e-38 132.6 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC80443.1 - 9.5e-06 24.9 11.6 9.5e-06 24.9 8.0 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC80443.1 - 0.18 10.9 20.0 0.011 14.8 9.1 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Pkinase PF00069.20 EMC80444.1 - 1.8e-52 178.0 0.1 2.4e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80444.1 - 3.6e-20 72.1 0.0 5.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC80444.1 - 0.0097 15.6 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC80444.1 - 0.018 14.1 0.1 0.068 12.2 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EMC80444.1 - 0.028 13.2 0.1 0.72 8.5 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-RING_2 PF13639.1 EMC80445.1 - 1.3e-13 50.5 7.6 2.1e-13 49.8 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC80445.1 - 2.4e-09 37.1 4.4 4.7e-09 36.2 3.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC80445.1 - 2.1e-07 30.4 7.8 3.5e-07 29.7 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC80445.1 - 8.6e-07 28.5 4.5 1.3e-06 27.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC80445.1 - 5.8e-06 26.2 8.0 9.4e-06 25.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC80445.1 - 9.7e-06 25.3 1.7 2.1e-05 24.2 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMC80445.1 - 1.2e-05 24.9 6.4 1.9e-05 24.3 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EMC80445.1 - 0.012 15.2 4.2 0.019 14.5 2.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EMC80445.1 - 0.12 11.9 2.9 0.25 10.9 2.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.2 EMC80445.1 - 1.3 9.0 5.7 3 7.9 3.9 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EMC80445.1 - 1.4 8.8 7.0 6.5 6.7 4.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EMC80445.1 - 7.1 6.7 6.7 14 5.8 4.7 1.5 1 0 0 1 1 1 0 RING-like domain E1-E2_ATPase PF00122.15 EMC80446.1 - 1.6e-22 79.6 0.1 2.9e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMC80446.1 - 1.4e-16 61.2 0.0 2.6e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC80446.1 - 2.2e-13 49.9 0.0 1.1e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EMC80446.1 - 9.1e-10 39.3 0.0 8.6e-09 36.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Colicin_im PF03857.8 EMC80446.1 - 0.0021 17.8 0.2 0.0021 17.8 0.1 2.7 2 0 0 2 2 2 1 Colicin immunity protein Hydrolase_3 PF08282.7 EMC80446.1 - 0.0091 15.6 0.6 0.029 13.9 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 EMC80446.1 - 0.027 13.2 0.3 0.046 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Shisa PF13908.1 EMC80447.1 - 2.5e-07 31.0 2.4 2.5e-07 31.0 1.7 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator IncA PF04156.9 EMC80447.1 - 0.017 14.7 0.3 0.021 14.4 0.2 1.1 1 0 0 1 1 1 0 IncA protein FAM163 PF15069.1 EMC80447.1 - 0.049 14.2 2.2 0.068 13.7 1.4 1.3 1 1 0 1 1 1 0 FAM163 family DUF342 PF03961.8 EMC80448.1 - 0.0094 14.4 6.1 0.053 11.9 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF342) Tox-ODYAM1 PF15642.1 EMC80448.1 - 0.027 13.1 6.3 0.037 12.6 4.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF1664 PF07889.7 EMC80448.1 - 0.48 10.2 8.4 4.3 7.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 EMC80448.1 - 0.58 10.0 7.6 1.3 8.8 0.7 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.10 EMC80448.1 - 1.1 8.4 11.2 1.6 7.8 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.5 EMC80448.1 - 9.4 6.3 14.5 6.6 6.8 2.7 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Myotub-related PF06602.9 EMC80449.1 - 4.8e-141 469.6 0.2 6.8e-141 469.1 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 EMC80449.1 - 0.0038 16.8 0.3 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC80449.1 - 0.0042 17.3 0.1 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EMC80449.1 - 0.0045 16.3 0.0 0.012 14.9 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2353 PF09789.4 EMC80449.1 - 0.023 13.9 0.2 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) WTX PF09422.5 EMC80450.1 - 3.9e-96 322.8 16.0 5.7e-96 322.3 11.1 1.2 1 0 0 1 1 1 1 WTX protein RhoGEF PF00621.15 EMC80451.1 - 2.5e-48 164.3 5.8 2.5e-48 164.3 4.0 1.7 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 EMC80451.1 - 4.4e-13 48.5 0.2 8.8e-13 47.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC80451.1 - 1.9e-10 39.9 2.1 4.7e-10 38.6 1.5 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EMC80451.1 - 3e-10 40.2 0.6 6e-10 39.2 0.4 1.5 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 EMC80451.1 - 5.9e-08 32.0 0.0 1.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.1 EMC80451.1 - 0.0017 18.2 0.6 0.022 14.7 0.1 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain C1q PF00386.16 EMC80452.1 - 1.8e-40 137.8 0.0 2.3e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC80452.1 - 7.8e-30 102.2 82.6 6.9e-11 41.5 17.7 3.7 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Roughex PF06020.6 EMC80452.1 - 0.18 10.4 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Peptidase_M3 PF01432.15 EMC80453.1 - 7.7e-145 483.4 0.0 1.1e-144 482.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 TNFR_c6 PF00020.13 EMC80454.1 - 3.6e-05 23.7 15.5 8.5e-05 22.5 1.2 6.0 4 2 1 6 6 6 2 TNFR/NGFR cysteine-rich region Sarcoglycan_1 PF04790.8 EMC80455.1 - 8.4e-108 359.5 0.0 9.7e-108 359.3 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 EMC80455.1 - 0.021 14.4 0.1 0.13 11.8 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) FGF PF00167.13 EMC80456.1 - 5.6e-46 155.2 0.2 6.7e-46 155.0 0.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_8 PF13833.1 EMC80457.1 - 4.5e-12 45.4 12.9 3.7e-08 32.8 0.0 5.3 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_7 PF13499.1 EMC80457.1 - 6.8e-10 38.9 6.0 0.0001 22.3 3.2 4.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC80457.1 - 4.1e-08 31.9 14.0 0.0011 18.0 0.1 5.4 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.1 EMC80457.1 - 1.6e-06 27.4 9.3 0.0085 15.9 0.2 4.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_4 PF12763.2 EMC80457.1 - 0.021 14.5 1.6 0.064 12.9 0.1 2.6 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand MHC_I PF00129.13 EMC80457.1 - 0.049 12.9 0.5 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 EF-hand_5 PF13202.1 EMC80457.1 - 0.25 10.7 7.6 8 6.0 0.7 3.9 3 0 0 3 3 3 0 EF hand zf-DHHC PF01529.15 EMC80458.1 - 2e-43 147.7 12.1 2e-43 147.7 8.4 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase HemY_N PF07219.8 EMC80458.1 - 0.65 9.5 0.0 0.65 9.5 0.0 2.5 2 1 1 3 3 3 0 HemY protein N-terminus Spt4 PF06093.8 EMC80458.1 - 1.3 9.0 6.3 2.5 8.0 4.4 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Pex24p PF06398.6 EMC80458.1 - 8.6 5.0 8.9 31 3.2 6.3 1.7 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin MRP-63 PF14978.1 EMC80459.1 - 9.6e-39 131.7 3.6 1.1e-38 131.5 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 CCDC92 PF14916.1 EMC80460.1 - 0.069 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Gemini_C4 PF01492.12 EMC80460.1 - 0.13 11.9 1.5 0.33 10.6 0.0 2.3 3 0 0 3 3 3 0 Geminivirus C4 protein SAP18 PF06487.7 EMC80461.1 - 4.1e-25 87.9 0.0 4.6e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF2312 PF10073.4 EMC80461.1 - 0.082 12.2 0.0 4.6 6.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Pkinase PF00069.20 EMC80463.1 - 8.7e-58 195.4 0.1 2.7e-37 128.3 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80463.1 - 6.3e-29 100.8 0.1 1.7e-20 73.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.19 EMC80463.1 - 2.1e-05 24.9 1.9 6.1e-05 23.4 1.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain UBA PF00627.26 EMC80463.1 - 5.8e-05 22.7 0.4 0.00018 21.1 0.3 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Kinase-like PF14531.1 EMC80463.1 - 0.0037 16.2 0.1 0.0096 14.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC80463.1 - 0.007 16.1 0.2 0.062 13.0 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC80463.1 - 0.037 13.1 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRM1_C PF08767.6 EMC80465.1 - 1.5e-05 24.1 1.2 1.5e-05 24.1 0.9 2.5 2 1 0 2 2 2 1 CRM1 C terminal N6-adenineMlase PF10237.4 EMC80467.1 - 1.3e-64 216.7 0.0 1.5e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 EMC80467.1 - 0.00061 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EMC80467.1 - 0.0024 17.4 0.0 0.0055 16.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC80467.1 - 0.04 13.9 0.0 0.053 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain IL17 PF06083.6 EMC80468.1 - 1.4e-28 98.7 0.4 2.3e-28 98.0 0.3 1.3 1 0 0 1 1 1 1 Interleukin-17 TPR_2 PF07719.12 EMC80469.1 - 5.3e-37 122.7 17.9 0.00012 21.6 0.1 11.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 EMC80469.1 - 7.2e-35 118.4 29.4 1.1e-12 47.4 1.5 7.3 4 2 3 8 8 8 6 TPR repeat TPR_1 PF00515.23 EMC80469.1 - 9.6e-35 116.7 30.0 9.4e-07 28.1 0.0 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 EMC80469.1 - 4.5e-29 100.1 28.2 1.1e-07 31.7 1.0 8.6 4 3 5 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.1 EMC80469.1 - 5.8e-24 81.9 9.2 0.00029 20.4 0.0 10.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC80469.1 - 1.2e-22 79.9 8.4 3.9e-06 27.1 0.1 7.3 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMC80469.1 - 3e-22 78.7 0.4 2.2e-06 28.1 0.1 6.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMC80469.1 - 1.6e-20 72.0 18.6 0.048 14.1 0.0 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC80469.1 - 8e-19 66.4 0.6 0.072 13.7 0.0 9.5 5 3 6 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC80469.1 - 8e-17 59.6 42.8 0.0015 18.1 0.1 11.9 11 2 2 13 13 12 5 Tetratricopeptide repeat Apc3 PF12895.2 EMC80469.1 - 1.3e-14 54.0 23.7 1.2e-06 28.5 2.1 6.3 3 3 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EMC80469.1 - 8.3e-09 35.0 15.4 0.19 11.7 0.1 8.8 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_21 PF09976.4 EMC80469.1 - 8.2e-06 25.8 11.0 0.00077 19.4 3.6 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC80469.1 - 4.1e-05 23.4 33.6 0.11 12.7 0.3 10.3 12 0 0 12 12 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC80469.1 - 8.2e-05 22.3 0.3 4.4 7.2 0.0 5.1 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EMC80469.1 - 0.00071 18.7 13.4 0.0049 15.9 0.5 4.1 2 1 1 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.7 EMC80469.1 - 0.003 18.1 15.5 3 8.6 0.0 7.2 7 0 0 7 7 6 1 Sel1 repeat BTAD PF03704.12 EMC80469.1 - 0.0048 17.2 0.0 1.4 9.1 0.0 3.9 4 0 0 4 4 4 1 Bacterial transcriptional activator domain FumaraseC_C PF10415.4 EMC80469.1 - 0.013 15.5 1.1 1.2 9.2 0.1 3.4 3 0 0 3 3 3 0 Fumarase C C-terminus TPR_20 PF14561.1 EMC80469.1 - 0.018 15.1 8.6 1.9 8.6 0.0 5.5 3 1 3 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC80469.1 - 0.076 12.9 9.4 27 4.7 0.1 6.1 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 EMC80469.1 - 0.18 11.8 8.5 58 3.9 0.0 6.5 8 0 0 8 8 6 0 PPR repeat MIT PF04212.13 EMC80469.1 - 2.3 8.1 27.7 0.69 9.8 0.5 7.1 6 2 1 7 7 6 0 MIT (microtubule interacting and transport) domain 3HCDH_N PF02737.13 EMC80470.1 - 7e-49 165.9 0.0 9.1e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMC80470.1 - 7.9e-15 55.0 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Connexin PF00029.14 EMC80471.1 - 3.9e-51 171.6 1.2 6.7e-51 170.8 0.1 1.9 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 EMC80471.1 - 1.9e-32 110.8 5.4 4e-32 109.8 3.8 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain COX6A PF02046.10 EMC80471.1 - 0.032 14.1 3.8 0.083 12.8 0.1 2.7 2 1 0 3 3 3 0 Cytochrome c oxidase subunit VIa 7tm_1 PF00001.16 EMC80471.1 - 0.039 13.0 4.0 0.25 10.4 0.3 2.3 1 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.1 EMC80471.1 - 0.059 13.7 0.6 24 5.4 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Connexin PF00029.14 EMC80472.1 - 7.3e-51 170.7 0.3 7.3e-51 170.7 0.2 1.8 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 EMC80472.1 - 9.7e-32 108.6 3.5 2.2e-31 107.4 2.5 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain COX6A PF02046.10 EMC80472.1 - 0.14 12.0 1.1 1.3 8.9 0.1 2.1 1 1 0 2 2 2 0 Cytochrome c oxidase subunit VIa DUF3816 PF12822.2 EMC80472.1 - 0.53 10.1 4.4 4 7.3 3.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) zf-FCS PF06467.9 EMC80473.1 - 1.9e-73 241.8 115.4 9.1e-12 44.4 2.3 10.5 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif DUF3504 PF12012.3 EMC80473.1 - 4e-67 225.2 0.4 4e-67 225.2 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) Arc_trans_TRASH PF08394.5 EMC80473.1 - 0.00033 20.7 5.2 0.00033 20.7 3.6 7.1 8 0 0 8 8 8 1 Archaeal TRASH domain YHS PF04945.8 EMC80473.1 - 0.084 12.7 0.1 0.084 12.7 0.1 8.4 9 0 0 9 9 9 0 YHS domain Ribosomal_L24e PF01246.15 EMC80473.1 - 0.14 12.0 30.3 0.15 11.9 0.4 7.6 6 1 1 7 7 7 0 Ribosomal protein L24e RRM_1 PF00076.17 EMC80474.1 - 6.1e-33 112.2 0.0 1e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 EMC80474.1 - 2.1e-27 95.2 3.4 2.8e-27 94.8 1.3 2.1 2 0 0 2 2 2 1 NOPS (NUC059) domain RRM_6 PF14259.1 EMC80474.1 - 7.2e-22 77.1 0.0 3.2e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC80474.1 - 3.8e-12 45.8 0.0 3.1e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3256 PF11644.3 EMC80474.1 - 0.2 11.1 0.4 0.32 10.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Aldedh PF00171.17 EMC80474.1 - 1.1 7.5 4.6 1.5 7.0 3.2 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ank_2 PF12796.2 EMC80476.1 - 3.8e-25 88.0 2.5 1.6e-13 50.7 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC80476.1 - 1.2e-20 72.1 1.9 2.6e-07 30.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMC80476.1 - 3.2e-20 71.6 0.2 6e-10 39.0 0.0 3.8 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC80476.1 - 5.1e-18 65.0 0.7 5.5e-06 26.7 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80476.1 - 2e-14 52.2 1.3 3.2e-05 23.7 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Chromo PF00385.19 EMC80476.1 - 1.8e-10 40.3 0.7 7.1e-10 38.4 0.5 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Snapin_Pallidin PF14712.1 EMC80478.1 - 0.027 14.7 1.3 0.027 14.7 0.9 2.3 3 0 0 3 3 3 0 Snapin/Pallidin Tcp10_C PF07202.8 EMC80479.1 - 1.3e-89 298.5 8.1 1.8e-89 298.0 5.6 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DUF4520 PF15016.1 EMC80479.1 - 0.0002 20.8 0.0 0.59 9.7 0.0 3.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4520) MORN_2 PF07661.8 EMC80479.1 - 0.00032 20.3 5.1 45 4.5 0.1 6.8 6 3 2 8 8 8 0 MORN repeat variant Plant_vir_prot PF01307.12 EMC80479.1 - 0.099 12.3 1.7 8.6 6.1 0.0 2.9 1 1 2 3 3 3 0 Plant viral movement protein Rib PF08428.5 EMC80479.1 - 0.49 10.1 5.3 19 5.0 0.1 4.5 3 1 1 4 4 4 0 Rib/alpha-like repeat TUDOR PF00567.19 EMC80480.1 - 6.9e-40 135.6 0.5 1.1e-20 73.6 0.0 2.8 2 1 0 2 2 2 2 Tudor domain Agenet PF05641.7 EMC80480.1 - 0.00026 21.0 0.1 0.54 10.4 0.0 2.8 2 0 0 2 2 2 2 Agenet domain TUDOR PF00567.19 EMC80481.1 - 1.4e-50 170.1 8.8 2.7e-22 78.8 0.1 5.0 4 1 0 4 4 4 3 Tudor domain STAS PF01740.16 EMC80481.1 - 0.026 13.9 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 STAS domain RhoGAP PF00620.22 EMC80483.1 - 1.2e-40 138.5 0.0 1.5e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF2183 PF09949.4 EMC80483.1 - 0.0066 16.3 0.0 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) SDA1 PF05285.7 EMC80484.1 - 0.0045 16.3 9.1 0.0055 16.0 6.3 1.0 1 0 0 1 1 1 1 SDA1 Fer2 PF00111.22 EMC80485.1 - 7.3e-08 32.0 0.2 9.8e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-CHY PF05495.7 EMC80485.1 - 0.026 14.6 0.5 0.06 13.5 0.4 1.6 1 1 0 1 1 1 0 CHY zinc finger ERM PF00769.14 EMC80486.1 - 1.6e-77 260.4 47.1 1.6e-77 260.4 32.7 2.6 2 1 1 3 3 3 1 Ezrin/radixin/moesin family FERM_C PF09380.5 EMC80486.1 - 2.4e-33 114.2 0.0 7e-33 112.7 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 EMC80486.1 - 3.6e-26 91.8 1.8 3.6e-26 91.8 1.2 3.5 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 EMC80486.1 - 2.8e-19 68.9 0.3 2.8e-19 68.9 0.2 2.9 3 0 0 3 3 3 1 FERM N-terminal domain RNase_Zc3h12a PF11977.3 EMC80487.1 - 1.6e-63 213.1 0.0 2.4e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain RNase_Zc3h12a_2 PF14626.1 EMC80487.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 PF14608.1 EMC80487.1 - 0.8 9.7 10.0 2.8 8.0 6.9 2.0 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Adeno_E1B_19K PF01691.11 EMC80489.1 - 0.083 12.1 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Mem_trans PF03547.13 EMC80490.1 - 0.00095 17.5 0.1 0.0011 17.3 0.1 1.0 1 0 0 1 1 1 1 Membrane transport protein TMEM154 PF15102.1 EMC80490.1 - 0.0011 18.7 0.1 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family 7tm_1 PF00001.16 EMC80490.1 - 0.003 16.7 0.0 0.0031 16.7 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Brr6_like_C_C PF10104.4 EMC80490.1 - 0.0037 16.7 1.6 0.0059 16.1 1.1 1.3 1 1 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CD34_antigen PF06365.7 EMC80490.1 - 0.0041 16.8 0.1 0.0051 16.4 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF1049 PF06305.6 EMC80490.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3609 PF12259.3 EMC80490.1 - 0.012 14.3 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) TMEM51 PF15345.1 EMC80490.1 - 0.012 15.3 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 RELT PF12606.3 EMC80490.1 - 0.019 14.0 0.6 0.03 13.4 0.4 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF3328 PF11807.3 EMC80490.1 - 0.021 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) 7TM_GPCR_Srv PF10323.4 EMC80490.1 - 0.021 13.9 0.6 0.027 13.5 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv SID-1_RNA_chan PF13965.1 EMC80490.1 - 0.021 13.0 0.1 0.022 12.9 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIRT PF15099.1 EMC80490.1 - 0.023 13.9 0.6 0.034 13.3 0.4 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family EphA2_TM PF14575.1 EMC80490.1 - 0.024 15.0 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OSTbeta PF15048.1 EMC80490.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Potyvirid-P3 PF13608.1 EMC80490.1 - 0.029 13.5 0.2 0.032 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein TMEM192 PF14802.1 EMC80490.1 - 0.033 13.0 0.1 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 TMEM192 family Ctr PF04145.10 EMC80490.1 - 0.046 13.7 0.1 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family SieB PF14163.1 EMC80490.1 - 0.048 13.2 0.2 0.069 12.7 0.2 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Ion_trans PF00520.26 EMC80490.1 - 0.054 12.7 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein FAM176 PF14851.1 EMC80490.1 - 0.067 12.8 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 FAM176 family MSC PF09402.5 EMC80490.1 - 0.068 11.8 0.1 0.082 11.6 0.1 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF2615 PF11027.3 EMC80490.1 - 0.069 13.0 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF3357 PF11837.3 EMC80490.1 - 0.095 12.5 0.2 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) OAD_gamma PF04277.8 EMC80490.1 - 0.099 13.0 0.1 0.21 11.9 0.0 1.6 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Chordopox_A13L PF05961.6 EMC80490.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DEAD PF00270.24 EMC80491.1 - 2.3e-44 150.8 0.1 6e-44 149.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMC80491.1 - 5.3e-22 77.1 0.4 1.1e-21 76.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMC80491.1 - 4.6e-21 74.4 0.0 1.1e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain bZIP_Maf PF03131.12 EMC80493.1 - 0.097 12.9 0.3 0.097 12.9 0.2 2.9 3 0 0 3 3 3 0 bZIP Maf transcription factor Glyco_transf_90 PF05686.7 EMC80494.1 - 5.3e-86 288.7 0.1 6.8e-86 288.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.14 EMC80494.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.1 EMC80494.1 - 0.0034 17.6 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thiolase_N PF00108.18 EMC80495.1 - 9.6e-103 342.7 1.9 1.5e-102 342.1 1.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC80495.1 - 4.3e-46 155.3 2.5 1.2e-45 153.8 1.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMC80495.1 - 3.4e-06 26.7 2.2 3.4e-06 26.7 1.5 2.4 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EMC80495.1 - 0.087 12.8 0.6 0.55 10.2 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cullin PF00888.17 EMC80496.1 - 6.2e-165 550.0 18.0 8.7e-165 549.6 12.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMC80496.1 - 2.9e-19 68.6 5.4 9.2e-19 67.0 3.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Ras PF00071.17 EMC80497.1 - 3.1e-29 101.4 0.1 3.8e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80497.1 - 0.0023 18.4 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC80497.1 - 0.021 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF914 PF06027.7 EMC80498.1 - 1.9e-135 451.0 21.3 2.1e-135 450.9 14.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EMC80498.1 - 2.2e-11 43.8 30.0 1.1e-05 25.4 10.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EMC80498.1 - 1.3e-10 40.6 24.2 1.8e-10 40.2 16.7 1.1 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EMC80498.1 - 1.3e-05 25.4 8.0 1.3e-05 25.4 5.5 2.5 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EMC80498.1 - 7.8e-05 22.3 28.8 0.0035 17.0 11.7 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family 7TMR-DISM_7TM PF07695.6 EMC80498.1 - 3.5 7.2 35.5 0.96 9.0 5.4 2.3 2 1 0 2 2 2 0 7TM diverse intracellular signalling Sarcolipin PF05366.6 EMC80499.1 - 7.5e-21 73.2 5.3 7.7e-21 73.1 3.6 1.0 1 0 0 1 1 1 1 Sarcolipin Phospholamban PF04272.9 EMC80499.1 - 0.00026 20.3 0.3 0.00028 20.2 0.2 1.1 1 0 0 1 1 1 1 Phospholamban ELMO_CED12 PF04727.8 EMC80500.1 - 6.9e-51 172.1 0.1 9.5e-51 171.7 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family 2OG-FeII_Oxy_2 PF13532.1 EMC80501.1 - 1.3e-23 83.8 0.0 2.7e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.7 EMC80501.1 - 1.5e-13 51.0 0.0 3.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 EMC80501.1 - 2.7e-09 37.1 0.0 5.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 EMC80501.1 - 3.6e-09 36.1 0.0 8.8e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 EMC80501.1 - 4.4e-07 29.7 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RRM_6 PF14259.1 EMC80501.1 - 6.1e-07 29.3 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.1 EMC80501.1 - 1.9e-06 27.5 0.0 3.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC80501.1 - 2e-06 28.0 0.1 1.4e-05 25.3 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMC80501.1 - 1.5e-05 24.7 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase RRM_5 PF13893.1 EMC80501.1 - 2.2e-05 24.2 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_12 PF08242.7 EMC80501.1 - 0.00013 22.3 0.0 0.00036 20.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF1891 PF09004.5 EMC80501.1 - 0.0014 17.9 0.4 0.0032 16.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) Methyltransf_26 PF13659.1 EMC80501.1 - 0.0031 17.5 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC80501.1 - 0.004 17.7 0.1 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC80501.1 - 0.024 13.7 0.0 0.074 12.1 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 EMC80501.1 - 0.083 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EMC80501.1 - 0.092 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CwfJ_C_1 PF04677.10 EMC80502.1 - 2.5e-38 130.4 0.7 7.3e-38 128.9 0.5 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EMC80502.1 - 3.2e-27 94.8 0.1 3.2e-27 94.8 0.1 3.4 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 VOMI PF03762.12 EMC80503.1 - 1.7e-32 112.7 0.7 2e-32 112.5 0.5 1.1 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) HNOBA PF07701.9 EMC80504.1 - 5.1e-63 212.2 3.0 2.2e-62 210.1 2.1 1.9 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.15 EMC80504.1 - 1.4e-60 203.8 0.0 2.4e-60 203.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 EMC80504.1 - 1.2e-17 63.9 0.0 2.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Heme NO binding RhoGAP PF00620.22 EMC80505.1 - 2.5e-79 264.1 3.7 9e-31 106.5 0.2 7.3 4 3 3 7 7 7 7 RhoGAP domain DUF4414 PF14377.1 EMC80505.1 - 0.00048 20.0 5.2 2.5 8.0 0.1 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) Phage_HK97_TLTM PF06120.6 EMC80505.1 - 0.059 12.7 1.3 58 2.8 0.1 3.8 4 0 0 4 4 4 0 Tail length tape measure protein Rubis-subs-bind PF09273.6 EMC80505.1 - 4.2 7.2 11.1 12 5.8 0.0 5.4 6 1 1 7 7 7 0 Rubisco LSMT substrate-binding Rsbr_N PF08678.5 EMC80505.1 - 8.1 6.3 7.3 1.2e+02 2.4 0.0 4.3 4 0 0 4 4 4 0 Rsbr N terminal ACPS PF01648.15 EMC80506.1 - 6.4e-18 64.6 0.1 5.6e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily Kelch_6 PF13964.1 EMC80507.1 - 2.6e-27 93.7 3.5 1.1e-05 25.3 0.0 6.7 2 2 4 6 6 6 5 Kelch motif BTB PF00651.26 EMC80507.1 - 2.8e-27 94.8 1.1 2.8e-27 94.8 0.7 2.2 2 0 0 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.20 EMC80507.1 - 4e-27 93.4 6.9 3.1e-07 29.8 0.0 6.2 6 1 0 6 6 6 5 Kelch motif BACK PF07707.10 EMC80507.1 - 2.4e-26 91.5 2.7 2.4e-26 91.5 1.9 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 EMC80507.1 - 6.2e-12 45.0 0.0 0.042 13.6 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC80507.1 - 1.1e-09 38.2 0.0 0.62 10.2 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC80507.1 - 1.5e-06 27.7 5.2 0.087 12.6 0.0 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 EMC80507.1 - 0.00062 19.6 0.1 2.8 8.0 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Myb_DNA-bind_5 PF13873.1 EMC80508.1 - 1.7e-22 79.1 6.7 1.7e-22 79.1 4.7 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EMC80508.1 - 0.008 16.2 2.3 0.02 15.0 1.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Flagellin_C PF00700.16 EMC80508.1 - 0.064 13.4 3.2 0.18 11.9 0.5 2.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region HALZ PF02183.13 EMC80508.1 - 0.081 12.6 39.1 0.26 11.0 1.3 6.0 3 2 3 6 6 6 0 Homeobox associated leucine zipper DUF2125 PF09898.4 EMC80508.1 - 0.089 12.0 1.6 0.53 9.5 0.9 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) Myb_DNA-binding PF00249.26 EMC80508.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain FtsL PF04999.8 EMC80508.1 - 2.6 7.7 33.0 0.67 9.7 3.0 4.3 2 2 2 4 4 4 0 Cell division protein FtsL ANF_receptor PF01094.23 EMC80509.1 - 1.2e-61 208.4 0.0 1.7e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 EMC80509.1 - 1.2e-60 203.5 0.0 2e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 EMC80509.1 - 6.1e-27 93.3 0.1 1.5e-26 92.1 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC80509.1 - 4.9e-25 88.1 0.0 9.2e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 EMC80509.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein CUB PF00431.15 EMC80510.1 - 1.5e-19 70.0 0.0 2.8e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 CUB domain PDGF PF00341.12 EMC80510.1 - 6.8e-15 54.9 6.2 1.2e-14 54.1 4.3 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain MIP-T3 PF10243.4 EMC80511.1 - 0.007 14.8 67.0 0.008 14.7 46.4 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 EMC80511.1 - 0.047 13.0 48.2 0.06 12.7 33.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF262 PF03235.9 EMC80511.1 - 0.31 10.9 18.1 0.37 10.7 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 CAF-1_p150 PF11600.3 EMC80511.1 - 0.39 10.0 75.8 0.45 9.8 52.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4045 PF13254.1 EMC80511.1 - 1.4 8.1 30.8 1.5 8.0 21.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GAGA_bind PF06217.7 EMC80511.1 - 1.4 8.8 29.9 2.1 8.2 20.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 EMC80511.1 - 1.6 6.6 37.0 1.8 6.4 25.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 EMC80511.1 - 2.2 7.5 34.8 2.7 7.2 24.1 1.1 1 0 0 1 1 1 0 SprA-related family Ycf1 PF05758.7 EMC80511.1 - 5.3 4.6 38.5 5.8 4.4 26.7 1.0 1 0 0 1 1 1 0 Ycf1 Raftlin PF15250.1 EMC80511.1 - 5.9 5.3 25.1 8.5 4.7 17.4 1.3 1 0 0 1 1 1 0 Raftlin TT_ORF1 PF02956.9 EMC80511.1 - 5.9 5.2 13.0 6.9 5.0 9.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 Gag_spuma PF03276.9 EMC80511.1 - 7.4 4.7 10.8 9 4.4 7.5 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Cullin_binding PF03556.10 EMC80512.1 - 3.5e-32 110.9 5.6 5e-32 110.4 3.9 1.2 1 0 0 1 1 1 1 Cullin binding Peptidase_M10 PF00413.19 EMC80513.1 - 3.1e-65 218.6 0.0 5.3e-65 217.8 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC80513.1 - 8.5e-41 137.4 3.2 2.1e-13 49.7 0.0 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 EMC80513.1 - 2.1e-11 43.5 0.0 4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 EMC80513.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EMC80513.1 - 0.017 14.4 0.1 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 EMC80513.1 - 0.062 13.2 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMC80513.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 EMC80513.1 - 0.18 11.2 0.0 1.9 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Reprolysin_4 PF13583.1 EMC80513.1 - 0.23 10.9 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC80514.1 - 3.2e-61 205.5 0.0 7.3e-61 204.4 0.0 1.6 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.14 EMC80514.1 - 4.6e-46 154.3 8.7 1.2e-14 53.7 0.0 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 EMC80514.1 - 4e-10 39.5 0.0 7.8e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 EMC80514.1 - 0.0054 16.1 0.1 3.6 6.9 0.1 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 EMC80514.1 - 0.0067 16.9 0.2 0.013 16.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC80514.1 - 0.04 13.8 0.3 0.072 12.9 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EMC80515.1 - 4.7e-60 201.7 0.1 8.6e-60 200.9 0.1 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC80515.1 - 7.1e-36 121.6 13.3 4.2e-09 35.9 0.4 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 EMC80515.1 - 2.1e-07 30.7 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 EMC80515.1 - 0.0002 20.7 0.2 0.24 10.7 0.3 2.6 2 1 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 EMC80515.1 - 0.0029 18.1 0.1 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC80515.1 - 0.0097 15.4 0.4 0.016 14.7 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC80515.1 - 0.015 15.2 0.2 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M64 PF09471.5 EMC80515.1 - 0.033 13.8 0.6 0.055 13.0 0.4 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Reprolysin_2 PF13574.1 EMC80515.1 - 0.066 13.2 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EMC80515.1 - 0.18 11.1 0.0 7.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EMC80516.1 - 2.3e-60 202.8 0.0 4.1e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC80516.1 - 2.4e-36 123.1 10.0 1.9e-11 43.4 0.4 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 EMC80516.1 - 5.1e-11 42.3 0.1 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 EMC80516.1 - 2.9e-06 27.8 0.0 9.5e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EMC80516.1 - 0.00025 20.5 0.1 0.4 10.0 0.0 2.4 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 EMC80516.1 - 0.0022 17.9 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMC80516.1 - 0.0049 16.4 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC80516.1 - 0.0051 16.8 0.0 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 EMC80516.1 - 0.0065 16.0 0.3 0.051 13.0 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3152) Peptidase_M54 PF07998.6 EMC80516.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin PF01421.14 EMC80516.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.19 EMC80517.1 - 3.8e-61 205.3 0.0 6.4e-61 204.6 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC80517.1 - 2.4e-40 136.0 6.4 1.6e-12 46.9 0.0 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 EMC80517.1 - 4.7e-13 48.8 0.1 3.6e-12 46.0 0.1 2.2 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 EMC80517.1 - 0.00041 20.8 0.1 0.00097 19.6 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EMC80517.1 - 0.0014 18.0 0.2 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 EMC80517.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMC80517.1 - 0.014 15.4 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC80517.1 - 0.02 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 EMC80517.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.3 EMC80517.1 - 0.11 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.19 EMC80518.1 - 4.2e-63 211.6 0.0 5.8e-63 211.2 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 EMC80518.1 - 1.9e-09 37.3 0.0 3.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 EMC80518.1 - 0.012 14.9 0.4 3.7 6.8 0.2 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 EMC80518.1 - 0.028 14.9 1.0 0.042 14.3 0.7 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC80518.1 - 0.064 12.7 0.2 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC80518.1 - 0.069 13.0 0.6 0.1 12.4 0.4 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M43 PF05572.8 EMC80518.1 - 0.073 12.6 0.2 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A MGC-24 PF05283.6 EMC80519.1 - 2.6e-07 30.6 14.7 3e-07 30.4 10.2 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) ATP-synt_S1 PF05827.7 EMC80519.1 - 0.023 14.0 0.3 0.026 13.8 0.2 1.1 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) gpUL132 PF11359.3 EMC80519.1 - 0.13 11.6 7.8 0.16 11.3 5.4 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 SoxE PF06525.6 EMC80519.1 - 0.73 9.0 6.1 0.79 8.9 4.2 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) MLANA PF14991.1 EMC80519.1 - 2.4 8.2 4.5 1.2 9.1 0.3 2.1 1 1 1 2 2 2 0 Protein melan-A BIR PF00653.16 EMC80520.1 - 8.7e-68 224.6 14.7 2.1e-23 82.5 0.4 3.8 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain CARD PF00619.16 EMC80520.1 - 7.3e-22 77.0 0.2 1.6e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Caspase recruitment domain zf-C3HC4_3 PF13920.1 EMC80520.1 - 7.9e-15 54.2 8.5 7.9e-15 54.2 5.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC80520.1 - 5.1e-06 26.4 12.1 5.1e-06 26.4 8.4 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EMC80520.1 - 0.0051 16.3 3.7 0.0051 16.3 2.5 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF2039 PF10217.4 EMC80520.1 - 0.27 11.2 4.5 0.82 9.7 3.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNA_pol_N PF01194.12 EMC80520.1 - 4.3 7.4 8.8 11 6.0 0.1 3.4 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit WW PF00397.21 EMC80521.1 - 1.7e-21 75.6 2.6 4.9e-10 39.0 0.1 2.6 2 0 0 2 2 2 2 WW domain MbtH PF03621.8 EMC80521.1 - 0.031 13.6 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 MbtH-like protein DUF4498 PF14926.1 EMC80522.1 - 1.6e-96 322.2 1.0 1.9e-96 322.0 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) CarbpepA_inh PF02977.10 EMC80522.1 - 1.4 8.6 4.7 0.73 9.4 0.2 2.5 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor K1377 PF15352.1 EMC80523.1 - 5.4e-259 862.1 49.1 6.3e-259 861.9 34.0 1.0 1 0 0 1 1 1 1 Susceptibility to monomelic amyotrophy Fibrinogen_C PF00147.13 EMC80524.1 - 3.8e-59 200.1 1.5 5e-59 199.7 1.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Phage_Gp23 PF10669.4 EMC80524.1 - 0.29 11.2 1.9 0.89 9.6 1.3 1.8 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MIP-T3 PF10243.4 EMC80525.1 - 0.00058 18.4 79.1 0.00063 18.3 54.8 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 EMC80525.1 - 0.19 9.7 42.2 0.2 9.6 29.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.1 EMC80525.1 - 0.37 8.8 12.0 0.43 8.6 8.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ycf1 PF05758.7 EMC80525.1 - 0.93 7.1 44.7 1.1 6.9 31.0 1.1 1 0 0 1 1 1 0 Ycf1 Mitofilin PF09731.4 EMC80525.1 - 2.5 6.6 42.6 2.5 6.6 29.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ion_trans PF00520.26 EMC80526.1 - 4.8e-37 127.1 17.7 4.8e-37 127.1 12.3 1.7 2 0 0 2 2 2 1 Ion transport protein TRP_2 PF08344.6 EMC80526.1 - 1.1e-30 105.3 1.4 2.2e-30 104.3 1.0 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 EMC80526.1 - 3.4e-13 49.7 1.5 3.5e-09 36.8 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PKD_channel PF08016.7 EMC80526.1 - 4.3e-13 48.4 13.2 7.4e-13 47.6 9.2 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ank PF00023.25 EMC80526.1 - 7.8e-09 34.9 4.3 0.065 13.0 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EMC80526.1 - 1.5e-08 34.9 0.5 3.5e-06 27.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC80526.1 - 8.4e-07 29.0 2.1 0.043 14.0 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80526.1 - 8.2e-06 25.5 4.9 8.3 6.9 0.1 5.0 4 0 0 4 4 4 1 Ankyrin repeat ING PF12998.2 EMC80526.1 - 0.3 11.3 6.5 0.46 10.7 2.7 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-DHHC PF01529.15 EMC80526.1 - 0.5 9.7 3.7 8.7 5.7 3.1 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase zf-C4 PF00105.13 EMC80527.1 - 9e-27 93.1 15.6 9e-27 93.1 10.8 1.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC80527.1 - 3.5e-26 91.5 7.3 5.1e-26 91.0 5.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Prog_receptor PF02161.10 EMC80527.1 - 0.00039 19.3 1.3 0.00048 19.0 0.9 1.1 1 0 0 1 1 1 1 Progesterone receptor DUF1676 PF07898.8 EMC80527.1 - 0.12 12.6 0.2 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) I-set PF07679.11 EMC80528.1 - 2.7e-75 248.2 0.0 3.6e-15 55.6 0.0 6.8 5 1 1 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC80528.1 - 4.7e-55 183.6 0.0 1.5e-08 34.6 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 EMC80528.1 - 3.3e-39 132.9 3.6 2.5e-12 46.7 0.1 4.6 4 0 0 4 4 4 4 Fibronectin type III domain Ig_3 PF13927.1 EMC80528.1 - 5.6e-38 129.2 2.7 5.1e-08 33.2 0.0 8.0 8 0 0 8 8 8 5 Immunoglobulin domain ig PF00047.20 EMC80528.1 - 7.9e-32 109.1 0.0 5.6e-06 26.3 0.0 7.2 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.12 EMC80528.1 - 7.8e-30 103.0 0.2 4e-05 23.4 0.0 7.8 6 2 0 6 6 6 6 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC80528.1 - 1.4e-08 34.4 4.4 0.46 10.4 0.0 5.7 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 EMC80528.1 - 6.3e-05 22.8 0.0 0.2 11.6 0.0 4.1 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Herpes_gE PF02480.11 EMC80528.1 - 0.011 13.9 0.0 18 3.4 0.0 4.0 4 1 1 5 5 5 0 Alphaherpesvirus glycoprotein E Interfer-bind PF09294.5 EMC80528.1 - 0.022 14.7 0.0 1.6 8.8 0.0 3.2 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III 7tm_2 PF00002.19 EMC80529.1 - 3.9e-31 107.9 20.3 5.4e-31 107.5 14.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 EMC80529.1 - 4.5e-07 29.8 3.8 8.5e-07 28.9 2.6 1.5 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain SH3_9 PF14604.1 EMC80530.1 - 2.8e-46 154.8 5.0 3.6e-16 58.4 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 EMC80530.1 - 4.4e-41 138.0 7.3 2.3e-13 49.3 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 EMC80530.1 - 7.8e-37 124.5 4.8 6e-13 48.0 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain Death PF00531.17 EMC80531.1 - 2.5e-14 52.7 0.1 5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Death domain GCC2_GCC3 PF07699.8 EMC80531.1 - 1.5e-06 27.6 27.0 0.00013 21.4 4.0 4.4 2 2 2 4 4 4 3 GCC2 and GCC3 TNFR_c6 PF00020.13 EMC80531.1 - 2.4e-06 27.4 29.8 0.0011 18.9 4.6 4.6 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region CARD PF00619.16 EMC80531.1 - 0.0071 16.1 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Caspase recruitment domain 7tm_2 PF00002.19 EMC80532.1 - 7.4e-37 126.7 22.3 1.4e-36 125.8 15.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 EMC80532.1 - 1.2e-13 50.9 2.1 1.2e-13 50.9 1.5 2.7 2 1 0 2 2 2 1 Latrophilin/CL-1-like GPS domain I-set PF07679.11 EMC80532.1 - 3.3e-13 49.2 2.9 1.3e-07 31.3 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain SEA PF01390.15 EMC80532.1 - 3e-12 46.1 0.1 1.1e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 SEA domain Ig_2 PF13895.1 EMC80532.1 - 1.8e-11 44.0 20.9 1.3e-07 31.5 0.1 4.8 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.20 EMC80532.1 - 4.3e-08 33.1 9.3 7.6e-07 29.1 0.1 3.8 2 1 0 2 2 2 1 Immunoglobulin domain DUF3497 PF12003.3 EMC80532.1 - 2.4e-07 30.3 4.3 4.6e-07 29.4 3.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) Ig_3 PF13927.1 EMC80532.1 - 9.9e-06 25.9 21.2 0.00097 19.6 0.3 4.4 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 EMC80532.1 - 2.3e-05 24.2 0.7 2.3e-05 24.2 0.5 3.7 4 1 0 4 4 4 1 Immunoglobulin V-set domain Astacin PF01400.19 EMC80533.1 - 4.8e-66 221.8 0.0 7.3e-66 221.2 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.18 EMC80533.1 - 4.1e-37 127.4 0.2 6.3e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 MAM domain MATH PF00917.21 EMC80533.1 - 3.4e-26 91.8 0.7 1.2e-25 90.0 0.1 2.1 2 0 0 2 2 2 1 MATH domain EGF PF00008.22 EMC80533.1 - 4.2e-09 36.1 4.9 1.3e-08 34.6 3.4 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.8 EMC80533.1 - 0.029 14.5 8.7 0.1 12.7 6.1 2.0 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.10 EMC80533.1 - 2.3 8.2 11.8 0.2 11.7 4.7 1.9 2 0 0 2 2 2 0 Calcium-binding EGF domain Astacin PF01400.19 EMC80534.1 - 3.5e-13 49.3 0.0 4.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TAS2R PF05296.8 EMC80535.1 - 1.2e-63 214.8 29.1 1.4e-63 214.6 20.2 1.0 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) Ni_hydr_CYTB PF01292.15 EMC80535.1 - 1.8 7.8 10.8 0.33 10.3 4.5 2.0 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 60KD_IMP PF02096.15 EMC80535.1 - 2 8.0 7.9 0.24 11.0 2.2 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein Ank_2 PF12796.2 EMC80536.1 - 2.5e-19 69.4 0.0 6.2e-18 64.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC80536.1 - 1.3e-15 57.3 0.2 1.3e-09 38.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC80536.1 - 1.6e-15 56.0 2.1 5.8e-08 32.1 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EMC80536.1 - 1.9e-13 49.1 0.6 2.4e-05 24.1 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMC80536.1 - 5.6e-13 48.6 1.4 9.3e-08 32.0 0.1 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Mito_carr PF00153.22 EMC80538.1 - 2.9e-69 228.8 0.6 2.4e-22 78.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 EMC80539.1 - 7.5e-58 196.1 0.2 1.3e-57 195.3 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 Calcipressin PF04847.7 EMC80540.1 - 2.3e-60 203.3 0.3 2.8e-60 203.0 0.2 1.1 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 EMC80540.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC80540.1 - 0.012 15.1 0.3 0.022 14.3 0.2 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phosphodiest PF01663.17 EMC80541.1 - 6.1e-66 223.2 2.1 7.2e-66 222.9 1.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC80541.1 - 7.3e-05 22.0 0.1 0.003 16.7 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EMC80541.1 - 0.0018 17.7 0.0 0.0065 15.8 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF131 PF01998.12 EMC80541.1 - 0.012 14.9 1.7 0.021 14.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF131 Phosphodiest PF01663.17 EMC80542.1 - 5.4e-80 269.4 0.5 6.4e-80 269.1 0.4 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC80542.1 - 4.9e-07 29.2 0.0 0.00027 20.2 0.0 2.3 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 EMC80542.1 - 0.00016 21.1 0.0 0.00032 20.1 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily TFIID-18kDa PF02269.11 EMC80543.1 - 2.5e-29 100.9 0.1 9.2e-29 99.1 0.2 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit 7tm_1 PF00001.16 EMC80544.1 - 8.6e-13 48.0 0.4 1.2e-12 47.5 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TNF PF00229.13 EMC80546.1 - 3e-36 123.7 0.1 4.9e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Voltage_CLC PF00654.15 EMC80548.1 - 1.4e-102 343.3 20.8 1.4e-102 343.3 14.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EMC80548.1 - 1.6e-16 59.8 1.9 2.2e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain RhoGAP PF00620.22 EMC80549.1 - 4.1e-32 110.9 0.0 6e-31 107.1 0.0 2.7 2 1 0 2 2 2 1 RhoGAP domain DUF464 PF04327.7 EMC80550.1 - 2.1 8.6 5.1 26 5.1 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF464) 7tm_1 PF00001.16 EMC80551.1 - 1.8e-38 132.1 14.7 2.4e-38 131.7 10.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4223 PF13978.1 EMC80551.1 - 0.63 9.8 0.1 0.63 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4223) Mito_carr PF00153.22 EMC80552.1 - 4.2e-29 100.0 0.1 5.1e-16 58.1 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Ras PF00071.17 EMC80553.1 - 3.5e-50 169.5 0.0 4e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80553.1 - 6.5e-22 78.2 0.0 1.3e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC80553.1 - 2.8e-15 56.0 0.0 3.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC80553.1 - 4.6e-09 35.7 0.0 6.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC80553.1 - 7.2e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC80553.1 - 1.8e-06 27.5 0.5 2.5e-05 23.7 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC80553.1 - 9.2e-06 24.9 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC80553.1 - 0.00045 19.0 0.4 0.0027 16.4 0.2 2.2 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 EMC80553.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S4e PF00900.15 EMC80554.1 - 1.3e-33 114.4 0.8 1.2e-32 111.4 0.4 2.1 2 0 0 2 2 2 1 Ribosomal family S4e KOW PF00467.24 EMC80554.1 - 7.9e-06 25.3 0.6 4.5e-05 22.9 0.1 2.6 2 1 0 2 2 2 1 KOW motif S4 PF01479.20 EMC80554.1 - 1.6e-05 24.2 0.0 3.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain RS4NT PF08071.7 EMC80554.1 - 0.0052 16.5 0.6 0.016 15.0 0.4 1.9 1 0 0 1 1 1 1 RS4NT (NUC023) domain Glyco_hydro_15 PF00723.16 EMC80555.1 - 1.5e-175 584.1 0.0 1.9e-175 583.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Flu_NP PF00506.13 EMC80555.1 - 0.22 9.9 0.0 0.34 9.3 0.0 1.2 1 0 0 1 1 1 0 Influenza virus nucleoprotein Cyclin_N PF00134.18 EMC80557.1 - 3.9e-07 29.6 0.1 6.2e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Gal_Lectin PF02140.13 EMC80558.1 - 6.2e-36 122.5 4.0 9e-18 64.3 0.2 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.1 EMC80558.1 - 5.1e-10 39.2 0.0 8.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 FAM176 family DUF3395 PF11875.3 EMC80558.1 - 0.16 11.5 0.1 15 5.2 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3395) Dickkopf_N PF04706.7 EMC80558.1 - 1.1 9.4 5.1 4.3 7.5 0.4 2.6 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region GST_N_3 PF13417.1 EMC80559.1 - 3.9e-07 30.2 0.0 7.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC80559.1 - 3.4e-06 26.8 0.0 6.4e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC80559.1 - 4.2e-06 26.6 0.0 7.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EMC80559.1 - 0.0012 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF1533 PF07550.6 EMC80559.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) GST_C_3 PF14497.1 EMC80559.1 - 0.033 14.6 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC80559.1 - 0.051 13.5 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FerB PF08150.7 EMC80561.1 - 5.7e-16 58.3 0.0 6e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 FerB (NUC096) domain C2 PF00168.25 EMC80562.1 - 4.6e-22 77.6 0.0 8.8e-14 51.1 0.0 3.6 3 1 0 4 4 4 3 C2 domain PTEN_C2 PF10409.4 EMC80562.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Lectin_leg-like PF03388.8 EMC80563.1 - 1.7e-62 210.5 0.0 5e-62 209.0 0.0 1.6 1 1 0 1 1 1 1 Legume-like lectin family PMP1_2 PF08114.6 EMC80563.1 - 0.0099 15.3 0.2 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 ATPase proteolipid family Col_cuticle_N PF01484.12 EMC80563.1 - 0.11 12.1 1.5 0.18 11.5 1.0 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Vpu PF00558.14 EMC80563.1 - 0.19 11.2 0.6 0.36 10.4 0.4 1.4 1 0 0 1 1 1 0 Vpu protein SRC-1 PF08832.5 EMC80564.1 - 0.096 13.4 0.1 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Steroid receptor coactivator FAM178 PF14816.1 EMC80565.1 - 2.3e-41 141.7 0.5 2.2e-38 131.9 0.3 3.0 1 1 0 1 1 1 1 Family of unknown function, FAM178 START PF01852.14 EMC80566.1 - 8.9e-08 31.6 0.2 1.1e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EMC80566.1 - 0.041 13.5 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) IL1 PF00340.14 EMC80567.1 - 2e-15 56.2 0.0 4e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Interleukin-1 / 18 PH_9 PF15410.1 EMC80567.1 - 1.4e-06 28.4 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.15 EMC80567.1 - 0.0048 16.5 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Bactofilin PF04519.8 EMC80567.1 - 0.041 13.8 0.0 47 4.0 0.0 3.8 2 1 1 3 3 3 0 Polymer-forming cytoskeletal Dehydratase_SU PF02287.10 EMC80567.1 - 0.18 11.5 0.2 67 3.2 0.0 4.0 4 1 0 4 4 4 0 Dehydratase small subunit DUF3245 PF11595.3 EMC80567.1 - 0.95 9.7 2.8 1.8 8.8 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) CDC45 PF02724.9 EMC80567.1 - 5.1 5.0 8.1 7.4 4.4 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein EMP24_GP25L PF01105.19 EMC80568.1 - 1.5e-46 158.4 0.0 1.6e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0128 PF03673.8 EMC80568.1 - 0.059 12.6 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Plectin PF00681.15 EMC80569.1 - 4.2e-52 173.4 0.0 6.5e-20 70.3 0.0 5.8 5 1 1 6 6 6 5 Plectin repeat tRNA_NucTran2_2 PF13735.1 EMC80569.1 - 0.031 14.0 0.2 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative TfuA PF07812.7 EMC80569.1 - 0.075 12.4 0.1 1 8.8 0.0 2.5 3 0 0 3 3 3 0 TfuA-like protein An_peroxidase PF03098.10 EMC80570.1 - 3.1e-98 329.4 0.0 2.6e-82 276.9 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.22 EMC80570.1 - 0.00084 19.2 13.2 0.0017 18.2 9.1 1.6 1 0 0 1 1 1 1 EGF-like domain PLA2_B PF01735.13 EMC80572.1 - 1.7e-155 517.9 0.0 2.1e-155 517.6 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.25 EMC80572.1 - 8.5e-14 51.1 0.1 2e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 C2 domain FANCAA PF15146.1 EMC80572.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fanconi anemia-associated EGF_CA PF07645.10 EMC80573.1 - 3.1e-12 46.2 8.0 3.1e-12 46.2 5.6 1.9 1 1 1 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 EMC80573.1 - 0.052 13.5 4.1 0.052 13.5 2.9 1.9 2 0 0 2 2 2 0 EGF domain DUF3844 PF12955.2 EMC80573.1 - 0.058 13.5 2.2 0.079 13.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) TILa PF12714.2 EMC80573.1 - 7.1 6.4 8.3 1.2 8.9 1.2 2.2 1 1 1 2 2 2 0 TILa domain T-box PF00907.17 EMC80575.1 - 2.4e-88 294.4 0.4 3.4e-88 293.9 0.3 1.2 1 0 0 1 1 1 1 T-box TBX PF12598.3 EMC80575.1 - 8.2e-06 26.1 0.1 2.1e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 T-box transcription factor Helicase_C_2 PF13307.1 EMC80576.1 - 1.9e-53 180.8 0.0 3.9e-53 179.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EMC80576.1 - 5.6e-47 159.3 0.1 5.6e-47 159.3 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 EMC80576.1 - 6.8e-05 22.4 0.0 0.15 11.5 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EMC80576.1 - 0.0072 16.1 0.6 1.1 9.0 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Bap31 PF05529.7 EMC80576.1 - 0.15 11.4 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Med13_N PF11597.3 EMC80577.1 - 5.9e-130 433.5 1.0 5.9e-130 433.5 0.7 2.4 3 0 0 3 3 3 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.7 EMC80577.1 - 7.1e-129 430.0 0.0 7.1e-129 430.0 0.0 2.7 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal zf-RING_2 PF13639.1 EMC80578.1 - 2.1e-11 43.4 9.8 5.1e-11 42.2 6.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC80578.1 - 1e-10 41.0 6.6 1.8e-10 40.3 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC80578.1 - 5.3e-10 39.1 10.9 1.1e-09 38.1 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC80578.1 - 1.1e-08 34.5 11.3 2.2e-08 33.6 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC80578.1 - 5.7e-08 32.3 9.2 1.2e-07 31.3 6.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC80578.1 - 1.8e-06 27.9 10.3 5.5e-06 26.3 7.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC80578.1 - 2.1e-06 27.3 5.4 3.1e-06 26.7 3.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC80578.1 - 1.4e-05 24.8 11.1 2.9e-05 23.8 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EMC80578.1 - 0.00059 19.5 2.2 0.0026 17.4 1.9 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EMC80578.1 - 0.014 15.1 7.3 0.38 10.6 5.1 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EMC80578.1 - 0.062 12.8 6.4 0.12 11.8 4.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 EMC80578.1 - 0.4 10.2 7.2 0.77 9.3 5.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAGA PF09237.6 EMC80578.1 - 0.55 9.8 3.3 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 GAGA factor UPF0547 PF10571.4 EMC80578.1 - 0.66 9.7 0.1 0.66 9.7 0.0 3.2 3 2 0 3 3 2 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.1 EMC80578.1 - 3.4 7.3 9.6 0.29 10.7 2.3 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EMC80578.1 - 6.7 6.6 8.6 16 5.3 5.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.20 EMC80579.1 - 9.6e-72 241.2 0.0 1.4e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80579.1 - 7.6e-37 126.7 0.0 9.8e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMC80579.1 - 9.1e-09 35.7 2.9 2.2e-08 34.4 2.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC80579.1 - 5.2e-08 32.2 0.0 1.2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FliT PF05400.8 EMC80579.1 - 0.068 13.5 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Kdo PF06293.9 EMC80579.1 - 0.076 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC80579.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family PTH2 PF01981.11 EMC80580.1 - 2.2e-50 169.2 0.0 2.4e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2000 PF09391.5 EMC80580.1 - 0.005 16.4 0.2 0.096 12.3 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2000) Clathrin PF00637.15 EMC80581.1 - 3.8e-212 694.4 39.6 2.3e-33 114.7 1.0 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EMC80581.1 - 4.5e-45 148.8 1.5 3.7e-06 26.8 0.0 7.7 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 EMC80581.1 - 3.4e-33 113.3 0.4 1.5e-32 111.2 0.3 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 EMC80581.1 - 1.1e-14 53.1 0.7 3.4e-14 51.4 0.5 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 EMC80581.1 - 3.6e-08 32.6 4.5 1.4e-05 24.1 0.2 4.3 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.1 EMC80581.1 - 1.2e-05 24.6 11.8 0.57 10.1 0.1 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC80581.1 - 5.1e-05 23.5 16.9 9.3 7.2 0.0 10.0 10 2 2 12 12 12 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC80581.1 - 0.0045 16.8 8.8 3.9 7.6 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC80581.1 - 0.0065 16.7 10.5 5.9 7.3 0.1 6.5 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC80581.1 - 0.079 12.5 13.9 0.19 11.4 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat OB_NTP_bind PF07717.11 EMC80582.1 - 5.5e-19 68.0 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC80582.1 - 8e-16 57.9 0.0 2.2e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC80582.1 - 7.7e-14 51.3 0.0 1.7e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC80582.1 - 0.0019 17.7 0.0 0.0064 16.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Yippee-Mis18 PF03226.9 EMC80583.1 - 4.9e-18 64.9 0.5 6.2e-18 64.6 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 EMC80583.1 - 0.009 16.1 5.5 0.031 14.4 3.8 1.8 1 1 0 1 1 1 1 CHY zinc finger NinE PF05322.6 EMC80583.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 NINE Protein AlcCBM31 PF11606.3 EMC80583.1 - 0.12 12.3 0.1 1.8 8.5 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein zf-FCS PF06467.9 EMC80583.1 - 0.2 11.3 2.2 9.7 5.9 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Evr1_Alr PF04777.8 EMC80583.1 - 0.37 10.7 3.9 0.8 9.6 0.6 2.1 1 1 1 2 2 2 0 Erv1 / Alr family GDPD PF03009.12 EMC80584.1 - 1.7e-24 86.7 0.0 7.5e-17 61.6 0.0 2.0 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EMC80584.1 - 1e-05 25.5 0.1 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2146 PF10220.4 EMC80585.1 - 2.7e-302 1005.1 0.0 3.4e-302 1004.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) DUF2450 PF10475.4 EMC80586.1 - 0.034 13.0 0.8 0.037 12.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 EMC80586.1 - 0.25 10.9 2.6 0.27 10.8 1.8 1.0 1 0 0 1 1 1 0 IncA protein zf-B_box PF00643.19 EMC80587.1 - 8.6e-10 38.3 8.9 8.6e-10 38.3 6.2 2.9 3 0 0 3 3 3 1 B-box zinc finger MATH PF00917.21 EMC80587.1 - 8.8e-07 29.1 0.0 2.8e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.1 EMC80587.1 - 4.3e-05 23.4 18.0 4.3e-05 23.4 12.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC80587.1 - 0.0006 19.4 14.8 0.0006 19.4 10.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF148 PF02520.12 EMC80587.1 - 0.015 15.0 4.3 0.37 10.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.7 EMC80587.1 - 0.055 13.2 5.1 0.9 9.3 1.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 EMC80587.1 - 0.081 11.3 1.3 0.15 10.4 0.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 EMC80587.1 - 0.92 9.7 13.3 1.3 9.1 3.0 3.3 3 0 0 3 3 3 0 Syntaxin MitMem_reg PF13012.1 EMC80587.1 - 8.7 6.4 11.9 4.1 7.5 1.7 3.4 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function PP2C PF00481.16 EMC80588.1 - 2.4e-64 217.2 0.2 3e-64 216.8 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMC80588.1 - 0.0003 20.2 0.1 0.0009 18.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMC80588.1 - 0.011 15.4 0.8 0.75 9.4 0.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Rad51 PF08423.6 EMC80589.1 - 8e-33 113.4 0.1 1.2e-30 106.2 0.1 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMC80589.1 - 2.4e-08 33.6 0.1 5.8e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EMC80589.1 - 0.00017 20.8 0.3 0.00041 19.5 0.1 1.7 1 1 1 2 2 2 1 KaiC RecA PF00154.16 EMC80589.1 - 0.00028 20.0 0.3 0.00074 18.6 0.1 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 EMC80589.1 - 0.0084 16.2 0.1 0.061 13.4 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EMC80589.1 - 0.011 16.5 0.1 0.092 13.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC80589.1 - 0.052 13.8 0.1 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EMC80589.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.4 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain AAA PF00004.24 EMC80589.1 - 0.073 13.2 0.1 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMC80589.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMC80589.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EMC80589.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.6 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EMC80589.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EMC80589.1 - 0.14 11.8 0.1 0.31 10.7 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EMC80589.1 - 1.3 8.7 3.7 12 5.7 0.1 2.8 3 0 0 3 3 3 0 Part of AAA domain 7tm_1 PF00001.16 EMC80590.1 - 3.4e-53 180.4 12.2 4.2e-53 180.1 8.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC80590.1 - 2.6e-10 39.8 10.4 3.6e-10 39.4 7.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 EMC80590.1 - 3.4e-07 29.6 3.2 3.4e-07 29.6 2.3 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 EMC80590.1 - 1.5e-06 27.5 12.3 4.8e-06 25.9 8.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.8 EMC80590.1 - 0.0058 15.5 13.1 0.0067 15.3 1.8 2.1 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) Cytochrom_B_N_2 PF13631.1 EMC80590.1 - 0.0079 16.0 1.4 0.013 15.2 0.5 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB 7TM_GPCR_Srh PF10318.4 EMC80590.1 - 0.24 10.1 13.3 0.012 14.5 5.3 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh C2 PF00168.25 EMC80591.1 - 1.5e-43 146.5 0.1 8.6e-24 83.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 EMC80591.1 - 8.8e-37 125.6 5.1 1.7e-36 124.6 3.5 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Cript PF10235.4 EMC80591.1 - 0.0034 17.7 1.0 0.013 15.8 0.6 2.1 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zf-piccolo PF05715.8 EMC80591.1 - 0.045 13.7 6.4 0.095 12.7 4.5 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger PHD PF00628.24 EMC80591.1 - 0.28 10.9 8.5 0.68 9.6 5.9 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EMC80591.1 - 1 9.1 11.3 0.4 10.4 4.0 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.19 EMC80591.1 - 3.9 7.4 11.6 0.4 10.6 4.5 2.0 1 1 1 2 2 2 0 B-box zinc finger Vps53_N PF04100.7 EMC80593.1 - 1.3e-135 452.1 2.0 3.3e-105 352.0 1.0 2.3 2 0 0 2 2 2 2 Vps53-like, N-terminal DUF2450 PF10475.4 EMC80593.1 - 7.8e-07 28.2 1.8 7.8e-07 28.2 1.2 2.1 2 1 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 EMC80593.1 - 0.00039 19.1 3.9 0.00074 18.2 2.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4413 PF14372.1 EMC80593.1 - 0.0073 16.2 1.5 0.031 14.2 0.0 3.0 4 1 0 4 4 2 1 Domain of unknown function (DUF4413) ING PF12998.2 EMC80593.1 - 0.014 15.6 3.7 0.055 13.7 2.5 2.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.7 EMC80593.1 - 0.017 14.8 5.4 0.31 10.8 1.7 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EMC80593.1 - 0.019 14.7 5.4 0.036 13.8 2.8 2.1 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin PF00261.15 EMC80593.1 - 0.027 13.5 3.3 0.021 13.9 0.8 1.9 2 0 0 2 2 2 0 Tropomyosin TBPIP PF07106.8 EMC80593.1 - 0.027 13.9 2.7 0.064 12.8 1.9 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nairo_nucleo PF02477.10 EMC80593.1 - 0.042 12.5 0.5 0.072 11.7 0.3 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein Tropomyosin_1 PF12718.2 EMC80593.1 - 0.063 13.1 5.0 0.023 14.5 0.9 2.1 2 0 0 2 2 2 0 Tropomyosin like GrpE PF01025.14 EMC80593.1 - 0.073 12.6 1.8 0.2 11.1 1.2 1.8 1 0 0 1 1 1 0 GrpE Vps51 PF08700.6 EMC80593.1 - 0.084 12.7 0.1 0.084 12.7 0.0 3.3 4 0 0 4 4 3 0 Vps51/Vps67 COG2 PF06148.6 EMC80593.1 - 0.12 12.2 6.4 0.65 9.8 1.8 3.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FhuF PF06276.7 EMC80593.1 - 0.13 12.2 1.9 2.4 8.1 0.0 3.1 2 1 1 3 3 2 0 Ferric iron reductase FhuF-like transporter Bac_luciferase PF00296.15 EMC80593.1 - 0.18 10.8 0.1 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase FUSC PF04632.7 EMC80593.1 - 0.18 10.1 0.2 0.27 9.6 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.1 EMC80593.1 - 0.23 9.8 9.6 0.022 13.2 3.3 1.7 2 1 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.17 EMC80593.1 - 0.61 10.1 6.4 0.55 10.2 1.9 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Snf7 PF03357.16 EMC80593.1 - 1.1 8.5 10.1 0.32 10.3 3.9 2.4 2 0 0 2 2 2 0 Snf7 TRAM_LAG1_CLN8 PF03798.11 EMC80594.1 - 5.1e-47 160.0 13.9 5.7e-47 159.8 9.6 1.0 1 0 0 1 1 1 1 TLC domain SpoU_methylase PF00588.14 EMC80596.1 - 2.8e-23 82.3 0.0 5.8e-21 74.8 0.0 2.3 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EMC80596.1 - 1.1e-08 35.1 0.0 2.9e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Thioredoxin_8 PF13905.1 EMC80597.1 - 4.5e-34 116.4 0.0 1.5e-30 105.1 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC80597.1 - 1.5e-14 54.1 0.0 6.3e-12 45.6 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EMC80597.1 - 1.5e-10 40.8 0.0 3.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.1 EMC80597.1 - 1.4e-08 34.7 0.1 1.4e-07 31.5 0.0 2.4 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.15 EMC80597.1 - 1.8e-08 33.9 0.1 2.3e-05 24.0 0.0 3.3 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_7 PF13899.1 EMC80597.1 - 6.2e-08 32.5 0.0 2.3e-06 27.5 0.0 3.2 3 1 0 3 3 2 1 Thioredoxin-like Redoxin PF08534.5 EMC80597.1 - 1.2e-07 31.3 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 EMC80597.1 - 0.00015 21.7 0.1 0.0013 18.6 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin SCO1-SenC PF02630.9 EMC80597.1 - 0.0042 16.7 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 SCO1/SenC HyaE PF07449.6 EMC80597.1 - 0.0072 16.2 0.3 31 4.5 0.0 3.7 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EMC80597.1 - 0.0079 15.7 0.0 1.3 8.6 0.0 3.2 2 1 0 2 2 2 1 Thioredoxin NADH_4Fe-4S PF10589.4 EMC80597.1 - 0.012 14.7 0.0 0.034 13.2 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region TrbC_Ftype PF09673.5 EMC80597.1 - 0.073 12.6 0.0 7 6.3 0.0 2.6 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein MatE PF01554.13 EMC80599.1 - 1.7e-51 174.0 28.9 7.8e-26 90.6 7.8 2.3 2 0 0 2 2 2 2 MatE Dispanin PF04505.7 EMC80599.1 - 0.12 11.9 3.4 0.4 10.2 0.3 2.8 2 0 0 2 2 2 0 Interferon-induced transmembrane protein WW PF00397.21 EMC80600.1 - 6.2e-07 29.1 0.2 1.2e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 WW domain C2 PF00168.25 EMC80600.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 C2 domain PMP22_Claudin PF00822.15 EMC80601.1 - 5.2e-24 84.7 0.9 6.6e-24 84.4 0.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC80601.1 - 7.3e-08 32.2 0.9 1.4e-07 31.3 0.3 1.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EMC80601.1 - 0.037 13.2 0.2 0.07 12.3 0.2 1.4 1 0 0 1 1 1 0 Clc-like IncA PF04156.9 EMC80601.1 - 0.076 12.6 0.2 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 IncA protein Spore_YabQ PF09578.5 EMC80601.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) DUF4131 PF13567.1 EMC80601.1 - 4.4 6.6 5.2 34 3.8 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3469 PF11952.3 EMC80602.1 - 2.8e-24 84.6 0.1 1.7e-20 72.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3469) Ish1 PF10281.4 EMC80602.1 - 0.028 14.4 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein ING PF12998.2 EMC80603.1 - 2.2e-13 50.4 4.0 2.2e-13 50.4 2.8 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMC80603.1 - 3e-10 39.6 7.9 3e-10 39.6 5.5 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EMC80603.1 - 0.009 15.3 3.4 0.024 13.9 2.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 EMC80603.1 - 0.012 15.6 6.7 0.32 11.0 3.9 2.6 2 0 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.1 EMC80603.1 - 0.26 11.4 6.8 0.051 13.7 1.7 2.1 2 1 0 2 2 2 0 PHD-like zinc-binding domain RR_TM4-6 PF06459.7 EMC80603.1 - 2.8 7.7 8.9 3.9 7.3 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EMC80603.1 - 3.9 7.2 7.0 5.6 6.6 4.8 1.2 1 0 0 1 1 1 0 DDHD domain Gryzun PF07919.7 EMC80604.1 - 9.6e-115 383.9 0.2 1.2e-114 383.6 0.1 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EMC80604.1 - 5.3e-75 252.0 0.8 1e-74 251.1 0.6 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 EMC80604.1 - 1.7e-24 85.3 0.1 8.5e-24 83.1 0.0 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Prefoldin PF02996.12 EMC80604.1 - 0.052 13.1 0.1 0.25 10.9 0.1 2.2 1 0 0 1 1 1 0 Prefoldin subunit TPR_11 PF13414.1 EMC80604.1 - 1.4 8.6 6.4 2.2 8.0 0.2 3.3 3 0 0 3 3 3 0 TPR repeat Phosphodiest PF01663.17 EMC80605.1 - 1.5e-69 235.0 0.2 1.7e-69 234.8 0.2 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC80605.1 - 0.0068 15.6 0.1 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.7 EMC80605.1 - 0.0089 15.7 0.3 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 PglZ domain DUF229 PF02995.12 EMC80605.1 - 0.099 11.0 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.7 EMC80605.1 - 0.2 10.4 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) IRF PF00605.12 EMC80606.1 - 3.8e-47 158.6 1.4 6.8e-47 157.8 1.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Heme_oxygenase PF01126.15 EMC80606.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Heme oxygenase Peptidase_C14 PF00656.17 EMC80607.1 - 1.5e-46 159.0 0.0 1.8e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Tachystatin_B PF11478.3 EMC80607.1 - 0.09 12.5 1.1 0.28 10.9 0.2 2.2 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B CENP-U PF13097.1 EMC80608.1 - 7.2e-42 143.2 6.1 7.2e-42 143.2 4.2 1.7 2 0 0 2 2 2 1 CENP-A nucleosome associated complex (NAC) subunit Spc7 PF08317.6 EMC80608.1 - 0.0012 17.5 6.3 0.0018 17.0 4.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4201 PF13870.1 EMC80608.1 - 0.0049 16.3 8.6 0.013 15.0 6.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) eIF3_N PF09440.5 EMC80608.1 - 0.02 15.0 2.3 0.05 13.7 1.6 1.6 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain IncA PF04156.9 EMC80608.1 - 0.18 11.3 11.6 0.5 9.9 8.1 1.7 1 1 0 1 1 1 0 IncA protein Sec8_exocyst PF04048.9 EMC80608.1 - 0.61 9.7 5.6 1.5 8.4 3.8 1.8 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF3735 PF12537.3 EMC80608.1 - 0.72 9.9 2.8 0.66 10.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) DUF4449 PF14613.1 EMC80608.1 - 0.72 9.7 8.4 0.46 10.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4449) I_LWEQ PF01608.12 EMC80608.1 - 0.74 9.7 7.6 0.26 11.2 1.9 2.2 2 0 0 2 2 2 0 I/LWEQ domain CorA PF01544.13 EMC80608.1 - 1.3 7.9 6.2 4.5 6.2 4.2 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 EMC80608.1 - 2.1 6.1 8.9 1.8 6.2 4.7 1.7 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EMC80608.1 - 3.3 8.0 5.8 16 5.8 1.8 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EMC80608.1 - 4 6.5 20.0 0.017 14.3 6.3 2.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 EMC80608.1 - 6.5 6.6 15.6 0.67 9.8 6.9 2.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 EMC80608.1 - 7.1 6.2 12.3 5.1 6.7 6.1 2.3 2 1 0 2 2 2 0 Mnd1 family AMP-binding PF00501.23 EMC80609.1 - 1.9e-92 309.8 0.0 2.4e-92 309.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC80609.1 - 0.018 15.9 0.0 0.056 14.4 0.0 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain GSG-1 PF07803.6 EMC80609.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 GSG1-like protein NVEALA PF14055.1 EMC80609.1 - 0.11 12.1 0.0 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 NVEALA protein HLH PF00010.21 EMC80610.1 - 8.6e-13 47.7 0.0 2.4e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC80610.1 - 2.1e-09 36.9 0.4 1.3e-08 34.4 0.1 2.4 2 1 1 3 3 3 1 Hairy Orange Mito_carr PF00153.22 EMC80611.1 - 5.7e-59 195.8 3.4 4.2e-23 80.8 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.7 EMC80612.1 - 2e-30 104.5 23.8 1e-06 29.1 0.0 6.3 7 0 0 7 7 7 5 Sel1 repeat TPR_6 PF13174.1 EMC80612.1 - 1.4e-05 25.2 5.1 3.7 8.2 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMC80612.1 - 0.0054 16.3 13.0 0.99 9.1 0.6 4.4 2 2 3 5 5 5 4 TPR repeat TPR_14 PF13428.1 EMC80612.1 - 0.011 16.3 9.4 20 6.1 0.0 5.3 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC80612.1 - 1.8 8.2 11.6 2.3 7.9 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 EMC80613.1 - 6.1e-09 36.0 0.0 8.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC80613.1 - 8.4e-09 35.4 2.2 3e-07 30.4 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC80613.1 - 1.5e-07 30.8 0.9 0.022 14.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC80613.1 - 3.3e-06 27.4 0.3 0.0099 16.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Peptidase_C78 PF07910.8 EMC80614.1 - 1.9e-54 184.0 0.1 2.3e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 Toxin_57 PF15535.1 EMC80614.1 - 3.3 7.8 6.6 2.4 8.2 0.4 2.9 3 0 0 3 3 3 0 Putative toxin 57 DUF4586 PF15239.1 EMC80615.1 - 6.5e-111 370.7 3.4 7.5e-111 370.4 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) PDZ PF00595.19 EMC80616.1 - 1.5e-15 57.1 0.0 3.9e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 EMC80616.1 - 1.2e-13 50.9 3.2 2.1e-13 50.1 2.2 1.4 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 EMC80616.1 - 0.00041 20.1 0.0 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 PDZ domain SH3_1 PF00018.23 EMC80617.1 - 3.9e-43 144.5 0.3 1.7e-14 52.9 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 EMC80617.1 - 4.4e-42 141.4 1.9 2.2e-14 52.7 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EMC80617.1 - 6.5e-31 105.5 0.7 3e-14 52.2 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.11 EMC80617.1 - 6.7e-29 99.0 7.6 8.4e-29 98.6 1.0 2.6 2 0 0 2 2 2 1 Sorbin homologous domain LRR_8 PF13855.1 EMC80618.1 - 2.2e-99 325.2 198.3 2.3e-13 49.6 4.4 11.0 3 3 13 16 16 16 16 Leucine rich repeat LRR_4 PF12799.2 EMC80618.1 - 4.8e-44 147.3 100.4 1.8e-05 24.2 3.9 13.1 8 3 4 13 13 13 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC80618.1 - 2.5e-26 91.8 26.4 2.6e-10 40.0 1.7 5.9 2 1 3 6 6 6 5 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC80618.1 - 1.5e-20 70.0 99.6 0.098 12.7 0.4 22.4 20 3 3 23 23 23 9 Leucine Rich Repeat TIR PF01582.15 EMC80618.1 - 1e-19 70.3 3.8 1.7e-19 69.6 2.6 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.1 EMC80618.1 - 1.8e-06 27.6 27.6 0.016 14.7 1.4 5.8 1 1 4 6 6 6 4 Leucine-rich repeat TIR_2 PF13676.1 EMC80618.1 - 2.4e-05 24.3 0.2 5.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.13 EMC80618.1 - 0.0071 15.8 1.6 0.014 14.8 0.0 2.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 EMC80618.1 - 0.065 13.3 113.4 0.068 13.2 0.3 20.1 17 4 4 21 21 21 0 Leucine Rich repeat DUF3719 PF12516.3 EMC80619.1 - 5.9e-22 77.0 0.1 2.6e-21 74.9 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) p450 PF00067.17 EMC80620.1 - 3.7e-94 315.8 0.0 4.2e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peripla_BP_1 PF00532.16 EMC80620.1 - 0.047 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family DUF3647 PF12363.3 EMC80620.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Phage protein Trypsin PF00089.21 EMC80621.1 - 1.7e-72 243.5 0.0 2.6e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 EMC80621.1 - 5.5e-30 102.9 33.4 8.3e-09 35.0 0.9 4.9 5 0 0 5 5 5 4 PAN domain PAN_4 PF14295.1 EMC80621.1 - 8.6e-19 66.9 22.6 1e-06 28.3 0.7 5.7 5 1 1 6 6 6 4 PAN domain DUF1986 PF09342.6 EMC80621.1 - 0.00013 21.4 1.0 0.0002 20.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC80621.1 - 0.022 14.7 0.0 0.061 13.3 0.0 1.8 1 0 0 1 1 1 0 Trypsin-like peptidase domain PAN_2 PF08276.6 EMC80621.1 - 3.2 7.6 20.9 0.056 13.2 0.8 4.3 4 0 0 4 4 4 0 PAN-like domain Cadherin PF00028.12 EMC80622.1 - 0 1688.1 100.5 9.7e-24 83.4 0.3 34.3 34 0 0 34 34 34 34 Cadherin domain Laminin_G_2 PF02210.19 EMC80622.1 - 1.9e-25 89.3 0.4 7.5e-25 87.4 0.3 2.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EMC80622.1 - 1.1e-18 67.4 0.0 5.4e-18 65.2 0.0 2.3 1 0 0 1 1 1 1 Laminin G domain Cadherin_2 PF08266.7 EMC80622.1 - 4.2e-18 64.6 0.8 6.5 6.4 0.0 17.0 21 0 0 21 21 21 2 Cadherin-like EGF PF00008.22 EMC80622.1 - 2.5e-16 59.2 76.0 3.8e-06 26.7 3.8 5.8 6 0 0 6 6 6 4 EGF-like domain EGF_CA PF07645.10 EMC80622.1 - 8.2e-06 25.7 10.7 8.2e-06 25.7 7.4 5.5 4 1 1 5 5 5 1 Calcium-binding EGF domain Laminin_G_3 PF13385.1 EMC80622.1 - 9.8e-06 25.8 0.1 3.7e-05 24.0 0.1 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily NfeD PF01957.13 EMC80622.1 - 0.5 10.5 0.1 1.1 9.3 0.0 1.5 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding MRP-S27 PF10037.4 EMC80623.1 - 1.7e-118 396.2 2.7 2.1e-118 395.9 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.1 EMC80623.1 - 3.5e-06 26.8 0.4 0.0073 16.2 0.0 2.0 1 1 1 2 2 2 2 PPR repeat family PPR_1 PF12854.2 EMC80623.1 - 0.00037 19.9 0.1 0.0013 18.1 0.0 1.9 2 0 0 2 2 2 1 PPR repeat Cas_DxTHG PF09455.5 EMC80623.1 - 0.0011 18.1 0.6 0.0031 16.7 0.1 1.8 1 1 0 2 2 2 1 CRISPR-associated (Cas) DxTHG family PPR PF01535.15 EMC80623.1 - 0.0017 18.1 0.1 0.0068 16.3 0.0 2.1 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 EMC80623.1 - 0.0021 18.2 0.0 0.031 14.5 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_19 PF14559.1 EMC80623.1 - 0.029 14.7 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SbmA_BacA PF05992.7 EMC80623.1 - 0.34 10.0 2.9 0.25 10.4 0.1 1.9 2 0 0 2 2 2 0 SbmA/BacA-like family zf-C2H2 PF00096.21 EMC80624.1 - 5e-46 152.3 93.5 0.00014 22.0 1.2 11.6 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC80624.1 - 1.8e-38 128.9 77.1 1.1e-05 25.4 0.4 12.3 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC80624.1 - 1.4e-34 115.9 82.4 0.0008 19.5 0.2 11.8 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC80624.1 - 3.6e-12 46.0 55.0 0.0017 18.4 0.8 11.3 10 1 1 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC80624.1 - 5.4e-07 29.2 46.5 0.0068 16.2 0.7 10.2 10 0 0 10 10 10 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC80624.1 - 0.00071 19.6 65.0 1.5 8.9 0.3 9.8 1 1 9 10 10 10 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC80624.1 - 0.0018 18.4 62.0 0.056 13.6 1.0 10.2 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-CHY PF05495.7 EMC80624.1 - 0.0026 17.8 47.7 0.71 10.0 6.3 5.2 1 1 4 5 5 5 3 CHY zinc finger zf-Sec23_Sec24 PF04810.10 EMC80624.1 - 0.19 11.2 0.0 0.19 11.2 0.0 6.0 8 0 0 8 8 8 0 Sec23/Sec24 zinc finger Rad50_zn_hook PF04423.9 EMC80624.1 - 0.27 10.7 9.2 14 5.2 0.1 4.8 4 1 1 5 5 5 0 Rad50 zinc hook motif HEAT PF02985.17 EMC80625.1 - 1.1e-34 115.3 12.4 0.0025 17.7 0.0 12.4 13 0 0 13 13 12 7 HEAT repeat HEAT_EZ PF13513.1 EMC80625.1 - 3.6e-30 103.6 0.9 2.3e-10 40.6 0.0 10.8 9 1 2 11 11 11 6 HEAT-like repeat HEAT_2 PF13646.1 EMC80625.1 - 5e-27 94.0 0.0 6.4e-06 26.3 0.0 7.5 4 3 7 11 11 11 8 HEAT repeats Arm PF00514.18 EMC80625.1 - 1.5e-17 62.7 5.1 0.011 15.5 0.0 8.7 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EMC80625.1 - 2.8e-15 56.4 1.8 0.00089 19.6 0.1 7.1 6 2 3 9 9 8 5 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EMC80625.1 - 9.2e-15 54.3 0.6 7e-14 51.5 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EMC80625.1 - 2.6e-14 53.4 3.9 0.00052 19.9 0.1 5.4 3 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EMC80625.1 - 3.9e-10 38.6 4.8 0.0039 15.5 0.4 5.2 3 2 1 4 4 4 4 Adaptin N terminal region UNC45-central PF11701.3 EMC80625.1 - 2.4e-05 24.0 4.5 0.053 13.1 0.3 4.0 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EMC80625.1 - 8.9e-05 21.9 1.4 0.2 10.9 0.0 4.6 4 1 1 5 5 5 1 CLASP N terminal Dopey_N PF04118.9 EMC80625.1 - 0.00024 20.0 0.1 0.00085 18.1 0.1 1.9 1 0 0 1 1 1 1 Dopey, N-terminal MMS19_C PF12460.3 EMC80625.1 - 0.0021 16.8 1.2 2.2 6.8 0.0 4.2 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal Proteasom_PSMB PF10508.4 EMC80625.1 - 0.0064 14.8 0.3 1.6 6.8 0.0 3.7 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit muHD PF10291.4 EMC80626.1 - 1.2e-67 227.8 0.8 3.9e-67 226.1 0.6 1.8 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EMC80626.1 - 9.7e-18 64.1 8.8 2.1e-17 63.0 0.0 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Prominin PF05478.6 EMC80626.1 - 0.038 11.5 6.7 0.07 10.6 4.6 1.4 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 EMC80626.1 - 0.14 11.9 8.9 1.9 8.3 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF445 PF04286.7 EMC80626.1 - 2.7 7.4 9.7 4.1 6.8 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Sec8_exocyst PF04048.9 EMC80626.1 - 4.6 6.8 12.3 2.3 7.8 2.3 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TMEM171 PF15471.1 EMC80627.1 - 1.6e-159 529.8 1.9 1.9e-159 529.6 1.3 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 PRA1 PF03208.14 EMC80627.1 - 3.9 6.8 9.0 0.16 11.3 0.4 2.5 2 1 1 3 3 3 0 PRA1 family protein DUF2371 PF10177.4 EMC80627.1 - 7.3 6.4 9.2 0.47 10.3 1.4 2.5 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF4526 PF15029.1 EMC80628.1 - 1.9e-112 374.4 0.2 2.1e-112 374.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4526) PIRT PF15099.1 EMC80628.1 - 0.022 13.9 0.4 0.034 13.3 0.3 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Tmemb_185A PF10269.4 EMC80628.1 - 0.063 12.8 0.1 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Lactamase_B PF00753.22 EMC80628.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF2371 PF10177.4 EMC80628.1 - 1.6 8.5 6.2 1.5 8.7 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) NAC PF01849.13 EMC80629.1 - 5.1e-24 83.5 0.3 8.6e-24 82.8 0.2 1.4 1 0 0 1 1 1 1 NAC domain LolA PF03548.10 EMC80629.1 - 0.072 12.7 0.6 0.091 12.3 0.4 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Ank_2 PF12796.2 EMC80630.1 - 6.2e-32 109.7 0.1 1.7e-21 76.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC80630.1 - 2.3e-29 99.7 0.1 5e-10 38.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EMC80630.1 - 1.2e-27 95.7 0.4 3.9e-09 36.7 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC80630.1 - 3.6e-24 84.2 1.0 2.8e-09 36.9 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80630.1 - 1.4e-22 77.5 0.0 3.4e-07 29.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat UTP15_C PF09384.5 EMC80631.1 - 2.6e-48 163.4 0.1 3.9e-48 162.8 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EMC80631.1 - 9.8e-29 98.1 5.0 1.1e-07 31.3 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMC80631.1 - 2.5e-05 24.0 0.0 0.052 13.3 0.0 3.3 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Ank_4 PF13637.1 EMC80632.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.25 EMC80632.1 - 0.092 12.5 0.1 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat TPR_9 PF13371.1 EMC80632.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.2 EMC80632.1 - 0.15 12.4 0.0 0.49 10.7 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Kelch_1 PF01344.20 EMC80633.1 - 1.2e-49 165.6 3.5 1.5e-11 43.6 0.0 5.6 5 0 0 5 5 5 5 Kelch motif BACK PF07707.10 EMC80633.1 - 7.3e-30 102.8 1.1 2.5e-29 101.1 0.5 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 EMC80633.1 - 3.4e-29 101.0 0.2 6.5e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 EMC80633.1 - 4e-29 99.5 4.3 4.5e-05 23.4 0.2 6.1 2 2 4 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EMC80633.1 - 3e-23 81.3 1.2 3.6e-08 33.0 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC80633.1 - 9.5e-23 79.7 0.6 3.8e-06 26.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC80633.1 - 3e-21 74.2 2.6 0.00014 21.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EMC80633.1 - 7.1e-18 64.1 1.2 8.5e-09 35.1 0.0 5.8 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 EMC80633.1 - 4.1e-05 22.8 0.2 8.7e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) PFU PF09070.6 EMC80633.1 - 0.13 12.2 0.1 0.66 9.9 0.0 2.2 3 0 0 3 3 3 0 PFU (PLAA family ubiquitin binding) Glyco_hydro_20 PF00728.17 EMC80634.1 - 4.1e-83 279.4 0.0 5.4e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EMC80634.1 - 1.6e-13 51.4 0.0 2.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EMC80634.1 - 0.043 14.3 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 GTP_EFTU PF00009.22 EMC80635.1 - 7.2e-63 211.4 0.0 1.1e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EMC80635.1 - 2.6e-28 97.6 0.0 1.2e-27 95.5 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 EMC80635.1 - 6.9e-24 83.5 0.0 1.7e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 EMC80635.1 - 7.2e-13 48.1 0.3 2.2e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EMC80635.1 - 1.6e-08 34.5 0.0 3.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC80635.1 - 0.0013 18.7 0.0 0.0036 17.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC80635.1 - 0.0045 17.4 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EMC80635.1 - 0.015 14.6 0.0 0.097 11.9 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.11 EMC80635.1 - 0.044 12.8 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Ribosomal_S8e PF01201.17 EMC80636.1 - 1.6e-30 105.9 13.2 5.9e-30 104.1 9.2 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e DUF4496 PF14908.1 EMC80638.1 - 0.0001 22.2 0.2 0.00098 19.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4496) BAH PF01426.13 EMC80639.1 - 2.1e-15 56.5 0.0 3.6e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 BAH domain DUF2090 PF09863.4 EMC80639.1 - 0.0018 17.2 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2090) Fascin PF06268.8 EMC80641.1 - 8.2e-15 54.8 0.1 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Fascin domain FANCAA PF15146.1 EMC80642.1 - 4e-161 536.7 0.7 6.5e-161 536.0 0.5 1.3 1 0 0 1 1 1 1 Fanconi anemia-associated NPL4 PF05021.10 EMC80643.1 - 2.8e-85 286.1 0.0 6.5e-85 284.9 0.0 1.6 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EMC80643.1 - 1.3e-59 200.0 0.4 2.1e-59 199.3 0.3 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EMC80643.1 - 2.5e-32 110.9 0.1 4.6e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PDE6_gamma PF04868.7 EMC80644.1 - 1.8e-51 171.9 1.1 2e-51 171.7 0.8 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit 7tm_3 PF00003.17 EMC80645.1 - 4.5e-40 137.4 14.7 5.8e-40 137.1 10.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_1 PF00001.16 EMC80646.1 - 7.9e-25 87.4 21.5 9.3e-25 87.2 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC80646.1 - 1.2e-06 27.9 2.5 1.2e-06 27.9 1.7 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF1472 PF07339.7 EMC80646.1 - 0.012 15.9 1.9 3 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1472) YWFCY PF14293.1 EMC80646.1 - 0.022 14.6 1.2 38 4.2 0.1 3.9 3 0 0 3 3 3 0 YWFCY protein DUF2116 PF09889.4 EMC80646.1 - 0.06 13.1 5.0 0.47 10.3 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) 7TM_GPCR_Srbc PF10316.4 EMC80646.1 - 0.84 8.8 18.3 0.016 14.4 4.9 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.4 EMC80646.1 - 0.89 8.5 20.3 0.012 14.7 7.2 2.4 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx WD40 PF00400.27 EMC80647.1 - 0.0079 16.0 1.2 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Ribosomal_L38e PF01781.13 EMC80648.1 - 2.4e-32 110.4 4.3 2.6e-32 110.3 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Pox_A3L PF05288.6 EMC80648.1 - 0.065 12.9 0.4 3.6 7.4 0.0 2.2 1 1 1 2 2 2 0 Poxvirus A3L Protein WRW PF10206.4 EMC80649.1 - 2.2e-21 75.8 0.0 2.6e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f FAM104 PF15434.1 EMC80651.1 - 1e-44 151.2 7.9 1.3e-44 150.9 5.5 1.1 1 0 0 1 1 1 1 Family 104 SR-25 PF10500.4 EMC80651.1 - 0.37 10.2 14.1 0.49 9.8 9.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 EMC80651.1 - 5.1 5.2 7.4 5.2 5.2 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein TGF_beta_GS PF08515.7 EMC80652.1 - 0.086 12.1 0.8 0.086 12.1 0.6 1.8 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif 7tm_1 PF00001.16 EMC80653.1 - 7.3e-68 228.4 20.5 1.1e-67 227.9 14.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC80653.1 - 2.2e-16 59.8 21.3 3e-16 59.3 14.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC80653.1 - 1.9e-11 43.6 8.4 1.9e-11 43.6 5.8 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC80653.1 - 7.7e-08 31.7 19.3 7.7e-08 31.7 13.4 2.2 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Herpes_US9 PF06072.6 EMC80653.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.9 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Zip PF02535.17 EMC80654.1 - 1.3e-27 96.6 0.3 2.8e-27 95.5 0.2 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Sox_N PF12444.3 EMC80655.1 - 9.1e-28 97.2 0.6 9.1e-28 97.2 0.4 2.4 2 1 0 2 2 2 1 Sox developmental protein N terminal HMG_box PF00505.14 EMC80655.1 - 2.5e-25 88.5 1.3 2.5e-25 88.5 0.9 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC80655.1 - 3e-11 43.5 1.0 5.3e-11 42.7 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EMC80655.1 - 0.075 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 IRK PF01007.15 EMC80656.1 - 1e-171 570.2 2.2 1.3e-171 569.9 1.5 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.5 EMC80656.1 - 1.7e-29 101.4 1.1 3.1e-29 100.5 0.8 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.11 EMC80656.1 - 0.00044 19.9 5.9 0.00097 18.8 4.1 1.6 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 EMC80656.1 - 0.34 10.1 7.6 0.52 9.5 5.3 1.2 1 0 0 1 1 1 0 Ion transport protein zf-DHHC PF01529.15 EMC80656.1 - 0.75 9.1 6.9 1.4 8.2 4.8 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase IRK PF01007.15 EMC80657.1 - 3.7e-141 469.8 2.1 4.7e-141 469.4 1.4 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC80657.1 - 0.00022 20.8 2.7 0.00052 19.6 1.9 1.7 1 0 0 1 1 1 1 Ion channel Pkinase PF00069.20 EMC80659.1 - 1.9e-06 27.2 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80659.1 - 0.00036 19.6 0.0 0.00043 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ABC_tran PF00005.22 EMC80660.1 - 1.3e-54 184.2 0.0 9.9e-29 100.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EMC80660.1 - 1.4e-26 93.3 47.8 1.5e-22 80.1 7.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EMC80660.1 - 2.9e-20 73.4 4.7 3.7e-06 27.1 0.0 5.3 4 1 0 5 5 5 4 AAA domain DUF258 PF03193.11 EMC80660.1 - 6.2e-10 38.5 1.3 0.00034 19.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC80660.1 - 1.2e-06 27.8 3.0 0.014 14.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMC80660.1 - 0.0001 21.6 0.7 0.2 10.8 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMC80660.1 - 0.00018 21.9 5.1 0.13 12.5 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMC80660.1 - 0.00082 19.4 0.8 0.076 12.9 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EMC80660.1 - 0.0022 17.9 0.5 3.2 7.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EMC80660.1 - 0.01 15.2 1.6 0.36 10.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMC80660.1 - 0.025 14.0 4.0 5.2 6.4 0.4 3.2 3 0 0 3 3 3 0 AAA-like domain DUF4162 PF13732.1 EMC80660.1 - 0.029 14.8 0.0 0.52 10.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_15 PF13175.1 EMC80660.1 - 0.035 13.1 2.4 0.095 11.7 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain SbcCD_C PF13558.1 EMC80660.1 - 0.037 13.9 0.0 7 6.6 0.0 3.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EMC80660.1 - 0.047 13.8 2.0 1.5 8.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.1 EMC80660.1 - 0.05 14.4 0.5 2.9 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMC80660.1 - 0.071 12.9 2.5 3.7 7.4 0.2 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EMC80660.1 - 0.09 12.2 1.7 0.88 8.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EMC80660.1 - 0.11 12.3 0.3 8 6.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EMC80660.1 - 0.16 11.9 0.1 24 4.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DLIC PF05783.6 EMC80660.1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) UPF0079 PF02367.12 EMC80660.1 - 0.2 11.3 2.4 10 5.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EMC80660.1 - 0.57 9.8 4.6 3.9 7.1 0.2 3.7 4 0 0 4 4 4 0 NACHT domain NB-ARC PF00931.17 EMC80660.1 - 0.69 8.7 3.4 12 4.6 0.4 2.4 2 0 0 2 2 2 0 NB-ARC domain NTPase_P4 PF11602.3 EMC80660.1 - 0.73 8.7 1.7 3.8 6.4 0.1 2.1 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 AAA_30 PF13604.1 EMC80660.1 - 0.77 9.3 2.8 25 4.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 EMC80660.1 - 1.3 7.7 2.2 1.2 7.8 0.2 1.7 2 0 0 2 2 2 0 ArgK protein DUF1129 PF06570.6 EMC80660.1 - 7 5.8 9.8 4.5 6.5 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) cNMP_binding PF00027.24 EMC80661.1 - 1.7e-43 146.3 0.0 9.1e-21 73.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EMC80661.1 - 4.6e-14 51.5 0.1 9.6e-14 50.5 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.6 EMC80661.1 - 0.013 14.9 2.1 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Cupin domain GXGXG PF01493.14 EMC80661.1 - 0.13 11.2 0.1 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 GXGXG motif WD40 PF00400.27 EMC80662.1 - 6.1e-05 22.7 0.5 0.1 12.5 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat BCAS3 PF12490.3 EMC80662.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Sulfatase_C PF14707.1 EMC80663.1 - 1.9e-21 76.6 0.0 2.6e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase MFS_1 PF07690.11 EMC80665.1 - 2e-33 115.6 19.6 1.7e-31 109.2 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC80665.1 - 2.3e-06 26.2 34.7 5.8e-06 24.9 7.5 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 EMC80665.1 - 0.00032 19.4 29.9 0.00032 19.3 5.8 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EMC80665.1 - 0.13 12.0 10.7 0.2 11.4 0.8 3.5 3 0 0 3 3 3 0 MFS_1 like family RGS PF00615.14 EMC80666.1 - 1.5e-31 108.8 0.0 2.8e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EMC80666.1 - 2.2e-12 46.5 0.1 6.9e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 EMC80666.1 - 3.5e-09 36.2 0.0 9.5e-09 34.8 0.0 1.8 2 0 0 2 2 2 1 GGL domain DUF4485 PF14846.1 EMC80667.1 - 3.1e-27 94.0 0.0 3.1e-27 94.0 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF4485) DUF148 PF02520.12 EMC80667.1 - 0.00088 19.0 12.5 0.00088 19.0 8.7 8.2 1 1 7 8 8 8 1 Domain of unknown function DUF148 Tup_N PF08581.5 EMC80667.1 - 0.0039 17.3 8.8 0.0039 17.3 6.1 10.6 4 3 6 10 10 10 2 Tup N-terminal zf-nanos PF05741.8 EMC80667.1 - 0.092 12.7 0.2 11 6.1 0.0 2.9 2 1 0 2 2 2 0 Nanos RNA binding domain Sushi PF00084.15 EMC80668.1 - 3.2e-40 136.2 27.7 3e-11 43.5 0.9 5.1 5 0 0 5 5 5 4 Sushi domain (SCR repeat) Sushi_2 PF09014.5 EMC80668.1 - 1e-25 89.2 1.5 1e-25 89.2 1.1 2.5 3 1 1 4 4 4 1 Beta-2-glycoprotein-1 fifth domain Meleagrin PF08189.6 EMC80668.1 - 0.28 10.7 9.8 3.1 7.3 0.4 4.5 5 0 0 5 5 5 0 Meleagrin/Cygnin family cEGF PF12662.2 EMC80668.1 - 1.7 8.3 6.8 6.9 6.4 0.2 3.7 3 0 0 3 3 3 0 Complement Clr-like EGF-like TFIID-31kDa PF02291.10 EMC80671.1 - 4.6e-60 201.0 0.1 6.6e-60 200.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EMC80671.1 - 3.8e-07 30.2 0.1 6.9e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EMC80671.1 - 2.1e-06 27.3 0.0 3.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EMC80671.1 - 0.00023 21.2 0.1 0.0004 20.4 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.8 EMC80671.1 - 0.037 13.8 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit 7tm_1 PF00001.16 EMC80672.1 - 5e-51 173.3 23.8 6.7e-51 172.8 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC80672.1 - 5.5e-09 35.5 24.1 5.5e-09 35.5 16.7 1.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 EMC80672.1 - 6.5e-06 25.4 20.9 8.9e-06 25.0 14.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.8 EMC80672.1 - 1.1e-05 24.4 20.6 1.6e-05 23.9 14.3 1.1 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) 7TM_GPCR_Srw PF10324.4 EMC80672.1 - 6.4e-05 22.2 23.1 0.00025 20.2 16.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.1 EMC80672.1 - 0.00045 20.0 8.7 0.00045 20.0 6.0 3.6 1 1 2 3 3 3 1 Olfactory receptor DUF4083 PF13314.1 EMC80672.1 - 0.67 9.8 5.8 0.21 11.4 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4083) 7tm_1 PF00001.16 EMC80673.1 - 2.8e-09 36.4 14.1 3.6e-09 36.1 9.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC80674.1 - 1.6e-54 184.7 22.8 1.6e-54 184.7 15.8 1.4 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC80674.1 - 4.7e-08 32.5 26.2 6.6e-08 32.0 18.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.10 EMC80674.1 - 0.077 12.7 16.9 0.022 14.5 1.5 2.7 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.4 EMC80674.1 - 0.29 10.1 33.8 1.5 7.8 23.4 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.16 EMC80675.1 - 2.4e-29 102.2 14.5 3.3e-29 101.7 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NdhL PF10716.4 EMC80675.1 - 2.1 8.1 8.3 0.58 9.9 2.0 2.6 1 1 1 2 2 2 0 NADH dehydrogenase transmembrane subunit 7tm_1 PF00001.16 EMC80676.1 - 4.9e-05 22.6 10.2 5.9e-05 22.3 7.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC80676.1 - 0.042 12.9 8.5 0.049 12.7 5.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.16 EMC80677.1 - 1.7e-45 155.2 22.0 3.2e-45 154.2 15.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC80678.1 - 2.3e-44 151.4 20.6 2.7e-44 151.2 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC80678.1 - 0.00011 21.4 19.2 0.00014 21.1 1.4 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF2975 PF11188.3 EMC80678.1 - 1.4 8.6 15.0 0.15 11.7 5.8 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2975) BRICHOS PF04089.9 EMC80679.1 - 4.7e-28 96.9 0.0 9.6e-28 95.9 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain Snf7 PF03357.16 EMC80680.1 - 3.1e-26 91.7 18.7 3.1e-26 91.7 13.0 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 EMC80680.1 - 2.6e-05 23.6 6.1 3.9e-05 23.1 4.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway MAP65_ASE1 PF03999.7 EMC80680.1 - 0.0044 15.6 5.1 0.0049 15.5 3.5 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Mu-like_Pro PF10123.4 EMC80680.1 - 0.005 16.3 7.9 0.0063 16.0 5.5 1.3 1 0 0 1 1 1 1 Mu-like prophage I protein DUF948 PF06103.6 EMC80680.1 - 0.24 11.2 6.5 0.29 11.0 3.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GrpE PF01025.14 EMC80680.1 - 0.32 10.5 10.8 0.14 11.6 5.8 1.7 2 1 0 2 2 2 0 GrpE DUF939_C PF11728.3 EMC80680.1 - 0.51 10.1 9.9 1 9.1 1.6 2.2 1 1 1 2 2 2 0 DUF939 C-terminal domain Fib_alpha PF08702.5 EMC80680.1 - 0.63 10.1 7.3 0.59 10.2 0.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1693 PF07984.7 EMC80681.1 - 1e-169 563.7 3.5 1.2e-169 563.5 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) NTF2 PF02136.15 EMC80683.1 - 9e-29 100.2 0.4 1e-28 100.0 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EMC80683.1 - 0.00071 19.3 0.1 0.00085 19.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SnoaL_2 PF12680.2 EMC80683.1 - 0.015 15.7 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.1 EMC80683.1 - 0.024 14.5 0.1 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain OST3_OST6 PF04756.8 EMC80684.1 - 2.1e-50 170.3 0.0 3.3e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EMC80684.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.1 EMC80684.1 - 0.061 12.7 4.4 0.089 12.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Yip1 PF04893.12 EMC80684.1 - 0.58 9.6 5.3 1.8 8.0 3.7 1.8 1 1 0 1 1 1 0 Yip1 domain COX7B PF05392.6 EMC80685.1 - 8.6e-27 92.5 0.0 9.2e-27 92.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB HMA PF00403.21 EMC80686.1 - 5.9e-81 266.5 13.6 1.4e-13 50.7 0.0 7.6 7 0 0 7 7 7 7 Heavy-metal-associated domain Hydrolase PF00702.21 EMC80686.1 - 1e-73 248.3 0.8 2.4e-73 247.1 0.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC80686.1 - 1.5e-39 135.4 0.4 1.5e-39 135.4 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EMC80686.1 - 3.9e-13 50.0 0.1 1.9e-12 47.7 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC80686.1 - 6.2e-05 22.6 5.9 0.00068 19.2 1.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMC80686.1 - 0.0051 16.6 0.1 0.036 13.9 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AHS1 PF02682.11 EMC80686.1 - 0.011 15.1 0.4 5.4 6.4 0.0 3.2 4 0 0 4 4 4 0 Allophanate hydrolase subunit 1 DUF1980 PF09323.5 EMC80686.1 - 0.058 13.1 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RRM_3 PF08777.6 EMC80686.1 - 0.089 12.6 0.0 53 3.7 0.0 4.3 5 0 0 5 5 5 0 RNA binding motif DUF2997 PF11211.3 EMC80686.1 - 2.1 7.7 10.4 20 4.6 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2997) PGK PF00162.14 EMC80687.1 - 5e-143 476.3 1.0 5.6e-143 476.1 0.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Ion_trans PF00520.26 EMC80688.1 - 4.3e-33 114.2 11.8 7.2e-33 113.5 8.2 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.6 EMC80688.1 - 1.4e-30 104.9 1.0 3.3e-30 103.8 0.7 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 EMC80688.1 - 7.9e-13 48.5 1.1 2.2e-07 31.1 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC80688.1 - 1.1e-09 38.5 0.0 0.00043 20.7 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC80688.1 - 1.3e-08 34.2 2.1 0.00064 19.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EMC80688.1 - 4.5e-06 26.4 5.2 0.043 14.0 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EMC80688.1 - 8.5e-06 25.8 0.0 0.14 12.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.7 EMC80688.1 - 0.00034 19.1 15.7 0.067 11.6 2.7 2.9 2 1 0 2 2 2 2 Polycystin cation channel DCX PF03607.12 EMC80690.1 - 1.1e-46 156.2 0.2 7.7e-24 83.0 0.0 2.3 2 0 0 2 2 2 2 Doublecortin Peptidase_C2 PF00648.16 EMC80691.1 - 9.5e-109 362.9 0.9 1.3e-108 362.4 0.6 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMC80691.1 - 2.2e-37 127.9 0.1 3.6e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.25 EMC80691.1 - 3.9e-14 52.2 0.1 9.8e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 EMC80693.1 - 1.7e-72 243.6 0.0 3.1e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80693.1 - 1.9e-45 155.0 0.0 2.9e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMC80693.1 - 1.1e-22 80.1 0.0 3.3e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EMC80693.1 - 2.9e-08 33.0 0.0 8.9e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMC80693.1 - 0.0011 18.7 0.0 0.012 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.7 EMC80693.1 - 0.0033 16.7 0.0 0.0074 15.5 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Kdo PF06293.9 EMC80693.1 - 0.14 11.2 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_60s PF00428.14 EMC80693.1 - 3.6 8.0 12.1 0.19 12.1 1.2 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein VWC PF00093.13 EMC80694.1 - 2.3e-27 94.8 59.4 8.8e-10 38.5 7.1 3.8 4 0 0 4 4 4 3 von Willebrand factor type C domain DUF1496 PF07383.7 EMC80694.1 - 0.00025 20.2 0.2 0.31 10.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1496) AMMECR1 PF01871.12 EMC80695.1 - 2.8e-44 150.2 0.0 3.4e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 AMP-binding PF00501.23 EMC80696.1 - 2.9e-99 332.3 0.0 3.5e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC80696.1 - 6.8e-05 23.7 0.0 0.00089 20.1 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase_Tyr PF07714.12 EMC80697.1 - 7e-93 310.4 0.0 9.6e-93 309.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC80697.1 - 2.6e-48 164.4 0.0 3.7e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC80697.1 - 1.6e-21 75.9 0.1 3.8e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain BTK PF00779.14 EMC80697.1 - 2.4e-15 55.8 2.1 5.5e-15 54.6 1.4 1.7 1 0 0 1 1 1 1 BTK motif SH3_1 PF00018.23 EMC80697.1 - 3.9e-15 54.9 0.1 9.3e-15 53.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EMC80697.1 - 4.6e-14 52.4 0.5 2e-11 43.9 0.1 2.5 2 0 0 2 2 2 2 PH domain SH3_9 PF14604.1 EMC80697.1 - 2.2e-10 39.9 0.1 5.8e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC80697.1 - 3.5e-07 29.5 0.0 9.3e-07 28.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 EMC80697.1 - 0.0001 21.3 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_3 PF08239.6 EMC80697.1 - 0.00015 21.8 0.0 0.00035 20.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain APH PF01636.18 EMC80697.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L44 PF00935.14 EMC80698.1 - 2.8e-32 110.5 9.5 2.8e-32 110.5 6.6 1.7 1 1 1 2 2 2 1 Ribosomal protein L44 Melibiase PF02065.13 EMC80699.1 - 2.8e-12 46.0 0.0 9.2e-12 44.3 0.0 1.7 1 1 1 2 2 2 1 Melibiase Neur_chan_LBD PF02931.18 EMC80700.1 - 1.8e-55 187.4 0.1 2.6e-55 186.9 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC80700.1 - 7.5e-45 153.6 1.0 1.3e-38 133.2 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Myelin_PLP PF01275.14 EMC80701.1 - 8.9e-125 414.8 16.0 1.2e-124 414.3 11.1 1.2 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Ras PF00071.17 EMC80702.1 - 1e-56 190.7 0.0 1.4e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC80702.1 - 2.7e-19 69.7 0.0 4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC80702.1 - 4e-10 39.1 0.0 4.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC80702.1 - 1e-06 28.0 0.0 1.9e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC80702.1 - 3.1e-06 27.1 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC80702.1 - 8.3e-06 25.3 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMC80702.1 - 0.0028 16.8 0.1 0.0086 15.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMC80702.1 - 0.0098 15.8 0.0 0.069 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC80702.1 - 0.077 13.1 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMC80702.1 - 0.11 11.8 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EMC80702.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase G-alpha PF00503.15 EMC80702.1 - 0.22 10.1 1.0 9.3 4.8 0.0 2.6 1 1 1 2 2 2 0 G-protein alpha subunit Thymosin PF01290.15 EMC80703.1 - 2.1e-20 72.0 9.6 2.3e-20 71.9 6.7 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family DUF4522 PF15022.1 EMC80703.1 - 0.055 13.1 0.2 0.058 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) WH2 PF02205.15 EMC80703.1 - 0.076 12.6 0.7 0.098 12.2 0.5 1.2 1 0 0 1 1 1 0 WH2 motif FERM_N PF09379.5 EMC80704.1 - 4.1e-07 29.9 0.1 5.3e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 FERM N-terminal domain PIH1 PF08190.7 EMC80705.1 - 1e-09 38.3 0.2 1.2e-09 38.1 0.2 1.0 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 RhoGAP PF00620.22 EMC80706.1 - 3.1e-51 172.9 1.7 1.3e-32 112.5 0.4 2.4 2 0 0 2 2 2 2 RhoGAP domain AAA_19 PF13245.1 EMC80706.1 - 0.00026 20.6 0.2 1.5 8.6 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain UvrD-helicase PF00580.16 EMC80706.1 - 0.00029 20.2 0.1 0.67 9.1 0.0 2.3 2 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain Cas_NE0113 PF09623.5 EMC80706.1 - 0.018 14.4 0.8 5.3 6.4 0.1 2.3 2 0 0 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) Spt20 PF12090.3 EMC80707.1 - 9.8e-40 135.8 0.7 1.9e-39 134.8 0.5 1.4 1 0 0 1 1 1 1 Spt20 family PAT1 PF09770.4 EMC80707.1 - 0.3 9.2 17.2 0.49 8.5 12.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNase_PH PF01138.16 EMC80708.1 - 4.2e-24 85.3 0.2 7.8e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMC80708.1 - 2.4e-11 43.3 0.0 4.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glycos_transf_2 PF00535.21 EMC80709.1 - 4.1e-23 81.9 0.0 5.1e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMC80709.1 - 1.8e-09 37.7 0.0 3.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMC80709.1 - 1e-05 24.7 0.0 1.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MH2 PF03166.9 EMC80710.1 - 1.2e-77 259.8 0.3 1.6e-77 259.4 0.2 1.1 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 EMC80710.1 - 1.3e-42 144.0 1.2 2.9e-42 142.8 0.8 1.7 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 EMC80710.1 - 2.3e-06 27.3 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.1 EMC80710.1 - 0.1 12.2 0.6 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) RFXA_RFXANK_bdg PF15289.1 EMC80711.1 - 7.6e-31 106.8 6.9 8.2e-31 106.7 4.8 1.0 1 0 0 1 1 1 1 Regulatory factor X-associated C-terminal binding domain DnaI_N PF07319.6 EMC80711.1 - 0.042 14.0 0.1 0.051 13.8 0.1 1.2 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus DUF1517 PF07466.6 EMC80711.1 - 0.11 11.5 0.2 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) MTP18 PF10558.4 EMC80712.1 - 0.048 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Cyclin_N PF00134.18 EMC80713.1 - 1.1e-47 160.7 0.1 2.3e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC80713.1 - 5.7e-31 106.9 0.5 1.9e-30 105.1 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain DCX PF03607.12 EMC80714.1 - 5.9e-40 134.6 0.2 1.4e-24 85.4 0.0 2.3 2 0 0 2 2 2 2 Doublecortin Pkinase PF00069.20 EMC80715.1 - 5.9e-74 248.4 0.0 8.3e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80715.1 - 5.7e-34 117.3 0.0 7.2e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC80715.1 - 0.00029 19.9 0.0 0.00063 18.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC80715.1 - 0.00086 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC80715.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMC80715.1 - 0.12 11.7 0.2 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Macoilin PF09726.4 EMC80715.1 - 6.7 4.8 7.2 10 4.2 5.0 1.2 1 0 0 1 1 1 0 Transmembrane protein CAP_GLY PF01302.20 EMC80716.1 - 4.7e-24 83.8 2.2 5.7e-24 83.5 1.5 1.1 1 0 0 1 1 1 1 CAP-Gly domain Dynactin PF12455.3 EMC80717.1 - 3e-40 137.8 1.8 3e-40 137.8 1.2 4.6 2 1 1 4 4 4 2 Dynein associated protein GAS PF13851.1 EMC80717.1 - 0.0078 15.4 18.1 0.0078 15.4 12.5 4.7 1 1 3 4 4 4 1 Growth-arrest specific micro-tubule binding Filament PF00038.16 EMC80717.1 - 0.03 13.8 82.9 0.41 10.0 18.2 2.7 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EMC80717.1 - 0.037 13.2 15.6 0.3 10.2 2.3 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 EMC80717.1 - 0.1 11.8 69.4 0.013 14.7 17.6 3.3 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain WEMBL PF05701.6 EMC80717.1 - 4 5.7 93.2 0.043 12.2 22.7 3.6 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Seryl_tRNA_N PF02403.17 EMC80717.1 - 6.7 6.7 77.8 0.52 10.3 13.5 5.4 1 1 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 EMC80717.1 - 7 6.9 34.0 0.64 10.3 0.4 6.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Papilloma_E5 PF03025.9 EMC80718.1 - 0.074 13.0 14.4 0.28 11.1 0.1 4.3 3 2 1 4 4 4 0 Papillomavirus E5 Collagen PF01391.13 EMC80719.1 - 7.9e-09 34.9 6.9 0.0041 16.6 0.0 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Lantibiotic_a PF14867.1 EMC80719.1 - 0.22 10.8 0.7 0.4 9.9 0.5 1.4 1 0 0 1 1 1 0 Lantibiotic alpha Drf_FH1 PF06346.7 EMC80719.1 - 0.22 11.0 21.0 0.28 10.6 14.6 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 TRC8_N PF13705.1 EMC80720.1 - 1.5e-68 231.6 12.6 1.7e-68 231.4 8.7 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain PLAC8 PF04749.12 EMC80720.1 - 1.5 9.3 5.5 2.8 8.5 3.8 1.6 1 1 0 1 1 1 0 PLAC8 family Ninjurin PF04923.7 EMC80720.1 - 5.4 6.7 6.1 1.2 8.8 0.8 2.1 1 1 1 2 2 2 0 Ninjurin Gastrin PF00918.12 EMC80721.1 - 7.3e-36 123.5 0.0 9.1e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Gastrin/cholecystokinin family RE_SinI PF09570.5 EMC80721.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 SinI restriction endonuclease DUF4245 PF14030.1 EMC80721.1 - 0.15 11.8 0.0 3.2 7.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) SUI1 PF01253.17 EMC80722.1 - 3.1e-30 103.8 2.0 3.9e-30 103.4 1.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mitoc_L55 PF09776.4 EMC80722.1 - 0.14 11.7 0.1 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Prolactin_RP PF15172.1 EMC80723.1 - 2.8e-23 80.8 5.6 4.8e-23 80.1 3.9 1.3 1 0 0 1 1 1 1 Prolactin-releasing peptide Rab_eff_C PF04698.7 EMC80724.1 - 1.5e-78 264.7 3.9 1.6e-78 264.5 2.7 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus FYVE_2 PF02318.11 EMC80725.1 - 1.7e-24 86.0 20.8 1.8e-24 85.9 14.4 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.16 EMC80725.1 - 0.21 11.5 23.8 0.29 11.0 15.2 2.1 1 1 1 2 2 2 0 FYVE zinc finger Siva PF05458.7 EMC80725.1 - 0.7 9.4 12.4 0.78 9.2 8.6 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-UDP PF14569.1 EMC80725.1 - 0.72 9.6 11.6 1 9.1 8.0 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger TMC PF07810.8 EMC80726.1 - 4.2e-20 72.2 0.8 7.8e-20 71.3 0.6 1.5 1 0 0 1 1 1 1 TMC domain Ribosomal_S2 PF00318.15 EMC80727.1 - 3.7e-43 147.1 0.0 1.1e-39 135.8 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 TAT_signal PF10518.4 EMC80727.1 - 1.3 9.2 6.7 0.71 10.0 1.6 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Mito_carr PF00153.22 EMC80728.1 - 3.3e-62 206.2 8.3 2.1e-20 72.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TRAPP PF04051.11 EMC80728.1 - 0.14 11.6 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component 7tm_1 PF00001.16 EMC80729.1 - 3.3e-54 183.7 21.7 4.3e-54 183.3 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC80729.1 - 0.00012 21.3 14.8 0.00012 21.3 10.3 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 EMC80729.1 - 0.00038 19.7 21.1 0.00053 19.2 14.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 EMC80730.1 - 2.3e-58 197.3 25.4 3e-58 196.9 17.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC80730.1 - 9.9e-10 37.9 27.0 1.4e-09 37.4 18.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 60KD_IMP PF02096.15 EMC80730.1 - 0.19 11.3 11.9 0.75 9.4 8.2 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein Metallophos PF00149.23 EMC80731.1 - 1.2e-13 50.9 0.1 3.4e-13 49.4 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC80731.1 - 1.4e-08 34.7 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.26 EMC80733.1 - 4.4e-29 100.6 3.7 6e-28 97.0 0.7 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 EMC80733.1 - 2.1e-28 98.1 3.3 2.1e-28 98.1 2.3 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Skp1_POZ PF03931.10 EMC80733.1 - 0.01 15.9 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Kelch_6 PF13964.1 EMC80733.1 - 0.093 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Kelch motif CENP-B_dimeris PF09026.5 EMC80734.1 - 0.028 14.6 6.5 0.08 13.1 4.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FKBP_C PF00254.23 EMC80735.1 - 2.8e-58 193.9 0.0 3.1e-27 94.3 0.0 4.0 4 0 0 4 4 4 2 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.27 EMC80735.1 - 4.2e-10 38.1 0.8 0.00021 20.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC80735.1 - 2.1e-08 34.1 3.7 5e-06 26.5 0.5 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC80735.1 - 1.4e-05 24.5 0.4 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC80735.1 - 3e-05 23.5 0.2 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC80735.1 - 4.2e-05 22.6 0.3 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 EF hand UMPH-1 PF05822.7 EMC80736.1 - 8.6e-120 398.5 5.4 1.1e-119 398.2 3.8 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 EMC80736.1 - 8e-05 22.8 0.2 0.00014 22.1 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_7 PF13840.1 EMC80736.1 - 0.0025 17.3 0.3 4.7 6.8 0.0 3.2 3 0 0 3 3 3 2 ACT domain NIF PF03031.13 EMC80736.1 - 0.017 14.7 1.5 0.97 9.0 0.0 2.8 3 1 1 4 4 4 0 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EMC80736.1 - 0.032 14.4 0.0 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase C_GCAxxG_C_C PF09719.5 EMC80736.1 - 0.055 13.2 0.5 0.095 12.5 0.4 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) cNMP_binding PF00027.24 EMC80737.1 - 4e-11 42.5 0.2 6.6e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EphA2_TM PF14575.1 EMC80737.1 - 0.051 13.9 0.1 0.082 13.3 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.14 EMC80737.1 - 0.44 10.1 3.1 1.9 8.1 0.1 2.5 3 0 0 3 3 3 0 Vpu protein DAP10 PF07213.6 EMC80737.1 - 0.73 9.6 4.2 1 9.1 0.1 2.7 3 0 0 3 3 3 0 DAP10 membrane protein SKG6 PF08693.5 EMC80737.1 - 9.4 5.6 8.7 18 4.7 6.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MRP-L27 PF09809.4 EMC80738.1 - 2e-37 127.2 0.0 2.2e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 WD40 PF00400.27 EMC80739.1 - 2.6e-10 39.7 6.6 4.8e-05 23.0 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF3312 PF11768.3 EMC80739.1 - 0.21 9.7 0.1 0.53 8.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) HNH_3 PF13392.1 EMC80740.1 - 3.2e-08 32.8 0.3 6.1e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease zf-MYND PF01753.13 EMC80740.1 - 5e-08 32.6 15.5 9e-08 31.8 10.7 1.5 1 0 0 1 1 1 1 MYND finger SHIPPO-rpt PF07004.7 EMC80741.1 - 0.0025 18.6 0.0 0.0057 17.4 0.0 1.7 1 0 0 1 1 1 1 Sperm-tail PG-rich repeat Ribosomal_L11 PF00298.14 EMC80742.1 - 4.3e-12 45.9 0.1 6e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EMC80742.1 - 8.2e-07 28.3 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain FKBP_C PF00254.23 EMC80743.1 - 5.7e-25 87.1 0.0 1.3e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.18 EMC80743.1 - 6.6e-05 22.6 0.3 0.00016 21.3 0.2 1.6 1 0 0 1 1 1 1 WH1 domain NPV_P10 PF05531.7 EMC80743.1 - 0.48 10.7 24.6 0.68 10.2 0.3 5.6 2 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EMC80743.1 - 3.3 6.0 55.0 1.6 7.0 19.2 2.1 1 1 1 2 2 2 0 AAA domain Ctr PF04145.10 EMC80744.1 - 3.8e-48 163.2 4.4 4.7e-48 162.8 3.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family WD40 PF00400.27 EMC80745.1 - 9.1e-58 190.2 19.8 7.8e-11 41.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EMC80745.1 - 3.2e-15 55.0 0.8 9e-15 53.6 0.5 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 EMC80745.1 - 0.014 13.6 0.5 1.9 6.5 0.0 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF1431 PF07248.7 EMC80745.1 - 0.083 12.8 0.7 0.19 11.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1431) WD40 PF00400.27 EMC80746.1 - 1.7e-40 135.4 15.7 7.1e-09 35.2 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMC80746.1 - 4.5e-06 25.0 1.5 0.039 12.0 0.0 3.7 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC80746.1 - 0.16 10.6 0.0 0.59 8.8 0.0 1.7 1 1 1 2 2 2 0 Nup133 N terminal like Ricin_B_lectin PF00652.17 EMC80746.1 - 0.18 11.8 2.4 1.3 9.0 0.3 2.8 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain Clathrin_propel PF01394.15 EMC80747.1 - 0.0081 16.3 3.0 3.6e+02 1.8 0.0 5.9 7 0 0 7 7 7 0 Clathrin propeller repeat Cornifin PF02389.10 EMC80747.1 - 0.65 9.7 45.6 1.7 8.3 31.6 1.6 1 1 0 1 1 1 0 Cornifin (SPRR) family Toxin_12 PF07740.7 EMC80747.1 - 3.7 8.1 50.1 1.2 9.6 1.1 7.2 7 0 0 7 7 7 0 Ion channel inhibitory toxin PRY PF13765.1 EMC80748.1 - 3.8e-11 42.3 0.0 9.5e-11 41.0 0.0 1.7 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 EMC80748.1 - 2e-10 40.7 0.0 3.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain HAD_2 PF13419.1 EMC80749.1 - 2.1e-24 86.6 0.0 2.6e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC80749.1 - 1.8e-10 41.6 0.0 2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMC80749.1 - 2.7e-09 36.5 0.0 4.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMC80749.1 - 0.047 13.5 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ALAD PF00490.16 EMC80750.1 - 1.4e-81 273.9 0.0 1.7e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CBFD_NFYB_HMF PF00808.18 EMC80751.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC80751.1 - 0.0069 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SpoU_methylase PF00588.14 EMC80751.1 - 0.009 15.8 0.1 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF1510 PF07423.6 EMC80751.1 - 0.013 14.8 10.1 0.012 14.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EMC80751.1 - 0.043 12.8 14.0 0.044 12.8 9.7 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 EMC80751.1 - 0.061 12.8 11.0 0.068 12.6 7.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 EMC80751.1 - 0.07 11.6 13.1 0.064 11.7 9.1 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EMC80751.1 - 0.16 10.0 11.4 0.16 10.0 7.9 1.0 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 EMC80751.1 - 0.28 10.6 12.3 0.31 10.5 8.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FLO_LFY PF01698.11 EMC80751.1 - 0.43 9.3 7.1 0.46 9.2 4.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2956 PF11169.3 EMC80751.1 - 0.53 10.2 8.5 0.79 9.7 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TraH_2 PF06871.6 EMC80751.1 - 0.54 9.6 5.0 0.64 9.4 3.5 1.1 1 0 0 1 1 1 0 TraH_2 Peptidase_S49_N PF08496.5 EMC80751.1 - 0.56 9.9 3.7 0.66 9.7 2.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Vfa1 PF08432.5 EMC80751.1 - 0.7 9.8 14.3 0.82 9.6 9.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 EMC80751.1 - 0.72 9.7 5.7 0.77 9.6 4.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CobT PF06213.7 EMC80751.1 - 1.5 7.9 16.1 1.6 7.8 11.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.12 EMC80751.1 - 1.5 8.5 5.4 1.4 8.6 3.7 1.1 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EMC80751.1 - 1.7 6.2 6.4 1.6 6.3 4.4 1.0 1 0 0 1 1 1 0 Ycf1 PBP_sp32 PF07222.7 EMC80751.1 - 3 6.9 8.7 3.2 6.8 6.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Myc_N PF01056.13 EMC80751.1 - 3.1 6.8 10.3 4 6.5 7.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4337 PF14235.1 EMC80751.1 - 7.7 6.3 6.0 9.3 6.0 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cytomega_UL84 PF06284.6 EMC80751.1 - 8.2 4.7 7.6 10 4.4 5.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RGS PF00615.14 EMC80752.1 - 3.9e-38 130.1 4.3 5.1e-38 129.8 3.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain zf-C2H2_6 PF13912.1 EMC80753.1 - 8e-11 41.4 26.3 2.8e-07 30.2 0.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMC80753.1 - 2.2e-07 30.7 24.1 0.0046 17.1 1.7 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC80753.1 - 1.1e-06 28.5 28.6 0.24 11.8 2.0 5.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.9 EMC80753.1 - 2.2e-05 23.9 0.1 5.7e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EMC80753.1 - 0.00062 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-H2C2_2 PF13465.1 EMC80753.1 - 0.028 14.7 23.2 0.92 9.9 1.3 5.6 5 0 0 5 5 5 0 Zinc-finger double domain DBD_Tnp_Hermes PF10683.4 EMC80753.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain zf-met PF12874.2 EMC80753.1 - 0.067 13.4 0.5 0.067 13.4 0.3 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EMC80753.1 - 0.18 11.6 23.6 1.2 8.9 2.2 4.8 5 0 0 5 5 5 0 BED zinc finger Lig_chan PF00060.21 EMC80754.1 - 2.2e-37 128.0 0.2 3.6e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 EMC80754.1 - 8.3e-30 103.7 0.0 8.7e-29 100.3 0.0 2.5 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.15 EMC80754.1 - 2.7e-21 75.8 0.0 6.5e-21 74.6 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 EMC80754.1 - 1.5e-19 69.7 0.0 3.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site CaM_bdg_C0 PF10562.4 EMC80754.1 - 4.3e-16 58.4 3.6 8e-16 57.5 2.5 1.5 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.1 EMC80754.1 - 0.00017 21.0 0.0 0.00044 19.7 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein Ion_trans_2 PF07885.11 EMC80754.1 - 0.026 14.2 0.6 0.064 12.9 0.4 1.7 1 0 0 1 1 1 0 Ion channel LRR_8 PF13855.1 EMC80755.1 - 7.3e-24 83.3 10.0 8.7e-14 51.0 1.7 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EMC80755.1 - 2e-12 46.4 8.1 3.4e-06 26.5 2.6 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.13 EMC80755.1 - 7.2e-10 38.0 3.2 2e-09 36.6 2.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.28 EMC80755.1 - 3.6e-07 29.2 12.0 0.0063 16.3 0.1 5.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC80755.1 - 6.8e-06 25.4 8.1 0.029 14.4 0.1 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EMC80755.1 - 7.1e-05 22.4 3.9 1.1 9.5 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich repeat zf-RING_2 PF13639.1 EMC80756.1 - 0.00095 18.9 12.5 0.00095 18.9 8.6 2.2 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EMC80756.1 - 0.0048 16.5 17.3 0.0049 16.5 10.0 2.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC80756.1 - 0.0052 16.7 17.5 0.022 14.8 10.0 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC80756.1 - 0.026 14.1 14.3 0.026 14.1 9.9 2.2 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) DUF329 PF03884.9 EMC80756.1 - 0.091 12.3 2.5 8.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-RING_UBOX PF13445.1 EMC80756.1 - 0.17 11.6 10.9 0.43 10.3 6.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger GcpE PF04551.9 EMC80756.1 - 0.42 9.3 3.8 1.5 7.5 2.6 1.7 1 1 0 1 1 1 0 GcpE protein FYVE PF01363.16 EMC80756.1 - 0.62 9.9 10.8 1.8 8.5 7.5 1.9 1 1 0 1 1 1 0 FYVE zinc finger ADK_lid PF05191.9 EMC80756.1 - 0.65 9.7 9.3 0.25 11.0 2.4 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid FYVE_2 PF02318.11 EMC80756.1 - 0.94 9.3 4.9 1.5 8.7 3.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger PhnA_Zn_Ribbon PF08274.7 EMC80756.1 - 3.2 7.6 10.3 23 4.9 0.0 3.8 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zf-RING_4 PF14570.1 EMC80756.1 - 6.4 6.4 12.8 23 4.6 8.3 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.2 EMC80756.1 - 6.5 6.6 12.1 9.9 6.0 1.6 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-C3HC4_4 PF15227.1 EMC80756.1 - 6.8 6.6 15.6 14 5.6 10.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC80759.1 - 4.2e-11 42.5 5.9 5.9e-11 42.0 4.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC80759.1 - 5.7e-10 38.7 5.3 8.5e-10 38.2 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC80759.1 - 2.1e-09 36.8 5.7 3.5e-09 36.1 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC80759.1 - 1.1e-08 34.5 6.4 2.6e-08 33.4 4.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC80759.1 - 6.9e-08 32.0 7.2 1.9e-07 30.6 0.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMC80759.1 - 5.1e-07 29.6 5.8 8.8e-07 28.8 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC80759.1 - 6.2e-07 29.1 3.7 1.4e-06 28.0 2.6 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC80759.1 - 1.2e-05 24.7 6.7 2.5e-05 23.7 4.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EMC80759.1 - 0.001 18.8 2.1 0.0015 18.3 1.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMC80759.1 - 0.0015 18.5 4.2 0.0015 18.5 2.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger DUF329 PF03884.9 EMC80759.1 - 0.027 14.0 2.5 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) NMD3 PF04981.8 EMC80759.1 - 0.035 13.2 2.2 0.039 13.0 1.5 1.0 1 0 0 1 1 1 0 NMD3 family zf-Sec23_Sec24 PF04810.10 EMC80759.1 - 0.076 12.5 3.2 0.43 10.1 0.9 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Prok-RING_4 PF14447.1 EMC80759.1 - 0.12 11.8 10.5 3 7.4 0.4 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF4428 PF14471.1 EMC80759.1 - 0.16 11.7 4.4 0.75 9.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-P11 PF03854.9 EMC80759.1 - 0.21 11.0 11.1 0.89 9.0 3.4 2.9 1 1 1 2 2 2 0 P-11 zinc finger Baculo_IE-1 PF05290.6 EMC80759.1 - 0.28 10.9 3.6 0.36 10.5 2.5 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-CHY PF05495.7 EMC80759.1 - 0.35 11.0 4.5 1 9.5 3.1 1.7 1 1 0 1 1 1 0 CHY zinc finger FYVE PF01363.16 EMC80759.1 - 0.51 10.2 4.2 0.95 9.4 2.5 1.7 1 1 1 2 2 2 0 FYVE zinc finger FANCL_C PF11793.3 EMC80759.1 - 1.7 8.6 6.0 7.8 6.5 4.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-MIZ PF02891.15 EMC80759.1 - 1.9 8.0 7.9 1.9 8.0 1.3 2.3 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger DZR PF12773.2 EMC80759.1 - 4.8 7.0 7.7 48 3.8 5.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.7 EMC80759.1 - 8.9 6.5 8.6 11 6.1 1.4 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Tmemb_185A PF10269.4 EMC80760.1 - 1.3e-09 38.0 15.8 1.1e-07 31.6 2.8 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein GDA1_CD39 PF01150.12 EMC80761.1 - 2.6e-104 349.1 0.0 3.4e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.12 EMC80762.1 - 8e-101 337.6 0.0 1e-100 337.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Adeno_E3_CR2 PF02439.10 EMC80762.1 - 0.21 11.1 1.4 0.4 10.2 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAM163 PF15069.1 EMC80762.1 - 2.3 8.7 8.4 0.23 12.0 1.9 2.1 2 1 0 2 2 2 0 FAM163 family GDA1_CD39 PF01150.12 EMC80763.1 - 3e-98 329.1 0.0 3.9e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SH3_1 PF00018.23 EMC80764.1 - 2.5e-16 58.7 0.0 8.7e-13 47.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC80764.1 - 1.3e-10 40.6 0.0 1.4e-08 34.1 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC80764.1 - 2.5e-09 36.4 0.0 3.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain TPR_2 PF07719.12 EMC80764.1 - 4.3e-07 29.3 0.5 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat PB1 PF00564.19 EMC80764.1 - 4.6e-07 29.4 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 EMC80764.1 - 1.5e-06 27.7 0.3 0.00043 19.8 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMC80764.1 - 1.1e-05 24.7 0.1 0.00084 18.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC80764.1 - 0.00076 19.3 2.3 0.0073 16.2 1.6 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC80764.1 - 0.02 14.7 0.5 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC80764.1 - 0.053 13.3 0.3 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC80764.1 - 0.11 13.2 1.9 0.74 10.6 0.3 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat BRO1 PF03097.13 EMC80765.1 - 3e-100 335.5 5.0 3e-100 335.5 3.5 2.6 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMC80765.1 - 1.1e-81 274.1 19.2 1.1e-81 274.1 13.3 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF592 PF04574.8 EMC80765.1 - 1.3 8.5 8.3 5.1 6.6 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF592) ALMT PF11744.3 EMC80765.1 - 4.7 5.7 9.1 1.5 7.4 4.2 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter NHL PF01436.16 EMC80766.1 - 1.5e-25 87.7 4.5 0.00022 21.0 0.1 6.9 7 0 0 7 7 7 6 NHL repeat SGL PF08450.7 EMC80766.1 - 0.011 15.1 0.0 0.1 11.9 0.0 2.6 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Kinesin PF00225.18 EMC80767.1 - 1.5e-110 369.0 0.3 2.5e-110 368.3 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EMC80767.1 - 2.5e-31 108.2 0.2 4.6e-22 78.2 0.0 3.5 2 2 0 2 2 2 2 Kinesin protein KIF1B PF12423.3 EMC80767.1 - 3.3e-16 59.0 0.0 9.9e-16 57.4 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EMC80767.1 - 5.2e-05 23.2 0.1 0.00067 19.7 0.0 2.5 2 0 0 2 2 2 1 FHA domain AAA_10 PF12846.2 EMC80767.1 - 0.046 13.1 0.8 0.5 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain KMP11 PF03037.11 EMC80767.1 - 0.23 12.1 5.7 0.24 12.0 0.7 2.9 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 DUF2203 PF09969.4 EMC80767.1 - 2.1 8.6 7.9 0.5 10.5 0.6 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SIR2 PF02146.12 EMC80768.1 - 2.3e-49 167.5 0.0 4.3e-49 166.6 0.0 1.4 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.11 EMC80768.1 - 0.004 15.9 0.1 0.036 12.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit NUC129 PF08157.6 EMC80769.1 - 4.5e-23 80.9 0.0 6.7e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 NUC129 domain CLTH PF10607.4 EMC80770.1 - 3.8e-48 162.8 0.0 5.3e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EMC80770.1 - 4.5e-26 91.3 0.9 6.8e-26 90.7 0.1 1.7 2 0 0 2 2 2 1 SPRY domain LisH PF08513.6 EMC80770.1 - 3.6e-06 26.5 0.0 7.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 LisH DUF1640 PF07798.6 EMC80771.1 - 4.2e-66 222.3 11.7 1.1e-65 221.0 8.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.13 EMC80771.1 - 0.0015 18.2 1.5 0.0015 18.2 1.0 2.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper CENP-F_N PF10481.4 EMC80771.1 - 0.021 14.2 3.4 0.027 13.8 2.4 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain Uds1 PF15456.1 EMC80771.1 - 0.039 13.9 3.8 0.056 13.4 2.7 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF972 PF06156.8 EMC80771.1 - 0.14 12.4 7.1 0.11 12.8 3.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EMC80771.1 - 0.18 11.2 10.5 0.026 13.9 3.6 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 Cullin_Nedd8 PF10557.4 EMC80771.1 - 0.43 10.4 7.0 0.19 11.5 1.5 2.7 2 1 1 3 3 3 0 Cullin protein neddylation domain FlaC_arch PF05377.6 EMC80771.1 - 1.9 8.4 5.9 1.5 8.7 0.7 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-RING_5 PF14634.1 EMC80772.1 - 7.4e-05 22.3 13.2 7.4e-05 22.3 9.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC80772.1 - 0.00055 19.7 12.1 0.00055 19.7 8.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC80772.1 - 0.0086 15.7 13.2 0.022 14.4 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phtf-FEM1B_bdg PF12129.3 EMC80772.1 - 0.042 13.2 4.2 0.065 12.5 2.9 1.2 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor FYVE PF01363.16 EMC80772.1 - 0.21 11.4 9.4 0.53 10.2 6.5 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.1 EMC80772.1 - 4.4 7.1 16.2 0.063 13.0 6.1 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Dysbindin PF04440.11 EMC80773.1 - 6.4e-48 162.2 9.7 1.3e-47 161.2 6.8 1.5 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) NPV_P10 PF05531.7 EMC80773.1 - 0.078 13.2 0.7 4.7 7.5 0.1 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.10 EMC80773.1 - 3.8 6.5 7.9 3.9 6.5 2.7 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit FERM_M PF00373.13 EMC80774.1 - 2.2e-18 66.6 3.1 9.1e-18 64.6 2.1 2.0 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.5 EMC80774.1 - 4.2e-13 49.1 0.1 1.3e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 FERM N-terminal domain zf-C3HC4_3 PF13920.1 EMC80774.1 - 5.6e-11 41.9 20.9 1.5e-10 40.5 14.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC80774.1 - 0.00018 21.4 22.5 0.00053 19.9 15.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.5 EMC80774.1 - 0.0054 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.1 EMC80774.1 - 0.021 14.3 12.6 0.048 13.2 8.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rab_eff_C PF04698.7 EMC80774.1 - 0.9 7.5 6.5 0.055 11.5 0.4 1.7 2 0 0 2 2 2 0 Rab effector MyRIP/melanophilin C-terminus IMPDH PF00478.20 EMC80775.1 - 5.7e-108 360.9 2.6 1e-104 350.2 1.8 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EMC80775.1 - 9.3e-05 21.4 1.3 0.00015 20.7 0.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 EMC80775.1 - 0.042 13.0 3.0 0.14 11.4 0.0 2.3 3 0 0 3 3 3 0 PcrB family RDD PF06271.7 EMC80776.1 - 4e-31 107.7 5.8 5.8e-31 107.2 4.0 1.2 1 0 0 1 1 1 1 RDD family DUF655 PF04919.7 EMC80776.1 - 0.11 12.1 0.2 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Nup153 PF08604.5 EMC80777.1 - 7.9e-117 391.0 20.8 7.9e-117 391.0 14.4 4.8 4 2 1 5 5 5 1 Nucleoporin Nup153-like zf-RanBP PF00641.13 EMC80777.1 - 1.3e-34 116.9 39.5 2.7e-12 45.5 2.1 4.6 5 0 0 5 5 5 4 Zn-finger in Ran binding protein and others Nucleoporin_FG PF13634.1 EMC80777.1 - 0.0022 18.2 31.4 0.0022 18.2 21.8 8.4 4 2 3 7 7 7 1 Nucleoporin FG repeat region DZR PF12773.2 EMC80777.1 - 0.45 10.3 16.8 13 5.6 6.7 3.4 2 1 0 2 2 2 0 Double zinc ribbon RRM_1 PF00076.17 EMC80778.1 - 4.3e-10 39.0 0.0 8.5e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC80778.1 - 0.00043 20.1 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BAR PF03114.13 EMC80778.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 BAR domain WD40 PF00400.27 EMC80779.1 - 5.5e-29 98.9 9.5 6.1e-08 32.2 0.4 6.2 5 2 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC80779.1 - 1.1e-05 23.8 1.1 0.0024 16.0 0.1 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMC80779.1 - 1.6e-05 24.6 0.3 0.029 14.1 0.1 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EMC80779.1 - 2.2e-05 24.2 0.3 0.16 11.6 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.8 EMC80779.1 - 0.0041 15.7 0.2 0.0077 14.8 0.1 1.5 1 1 0 1 1 1 1 Vps16, N-terminal region RNA_pol_Rpc4 PF05132.9 EMC80779.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 RNA polymerase III RPC4 Tmemb_14 PF03647.8 EMC80780.1 - 3.7e-31 107.3 8.9 4.2e-31 107.2 6.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CytB6-F_Fe-S PF08802.5 EMC80780.1 - 1 9.3 6.9 1.8 8.6 0.6 3.0 2 1 1 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Gly-zipper_OmpA PF13436.1 EMC80780.1 - 3.1 7.4 4.9 1.7 8.3 2.0 1.5 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain GFO_IDH_MocA_C PF02894.12 EMC80781.1 - 0.0015 18.2 0.1 0.0045 16.7 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain RabGAP-TBC PF00566.13 EMC80782.1 - 1.7e-06 27.6 5.5 3.6e-05 23.3 3.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RPEL PF02755.10 EMC80783.1 - 4.3e-37 124.4 26.5 4.8e-10 38.4 1.6 4.5 4 0 0 4 4 4 4 RPEL repeat Endothelin PF00322.12 EMC80784.1 - 1.3e-20 72.3 12.2 1.7e-17 62.3 1.9 3.0 3 0 0 3 3 3 2 Endothelin family zf-C2H2 PF00096.21 EMC80785.1 - 7.6e-18 63.7 45.3 0.00019 21.5 1.1 6.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC80785.1 - 2e-10 40.3 11.3 1.5e-07 31.3 0.4 6.2 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC80785.1 - 5e-09 36.0 40.0 0.007 16.4 1.0 5.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMC80785.1 - 3.5e-05 23.8 35.8 0.0034 17.6 1.4 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC80785.1 - 6.1e-05 22.7 2.3 6.1e-05 22.7 1.6 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC80785.1 - 2.6 8.4 31.0 0.049 13.8 3.0 5.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-met PF12874.2 EMC80785.1 - 6.6 7.0 42.6 1.3 9.3 0.8 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Far-17a_AIG1 PF04750.9 EMC80786.1 - 2.6e-58 196.4 16.7 3e-58 196.2 11.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein MerC PF03203.9 EMC80786.1 - 2.9 8.3 8.1 13 6.1 0.4 3.2 3 1 1 4 4 4 0 MerC mercury resistance protein DUF2306 PF10067.4 EMC80786.1 - 4.4 7.4 9.1 1.2 9.2 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) Tmemb_170 PF10190.4 EMC80787.1 - 7.3e-47 157.7 10.9 8e-47 157.6 7.6 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1691 PF07950.6 EMC80787.1 - 0.15 11.9 1.4 0.18 11.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) EpsG PF14897.1 EMC80787.1 - 0.33 9.8 4.0 0.35 9.7 2.8 1.1 1 0 0 1 1 1 0 EpsG family Sdh_cyt PF01127.17 EMC80787.1 - 1.2 9.0 9.6 0.39 10.5 4.5 1.7 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF3513 PF12026.3 EMC80788.1 - 4e-90 300.9 7.0 4.8e-90 300.7 3.8 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3513) Serine_rich PF08824.5 EMC80788.1 - 2.4e-60 202.8 2.6 2.4e-60 202.8 1.8 2.0 2 0 0 2 2 2 1 Serine rich protein interaction domain SH3_9 PF14604.1 EMC80788.1 - 5.4e-14 51.5 0.0 1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC80788.1 - 1.7e-11 43.3 0.0 3.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC80788.1 - 7.3e-11 41.3 0.0 1.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ELO PF01151.13 EMC80789.1 - 1.5e-63 214.4 22.1 1.7e-63 214.2 15.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GCM PF03615.10 EMC80790.1 - 9.8e-78 258.6 1.8 1.5e-77 258.0 1.3 1.3 1 0 0 1 1 1 1 GCM motif protein GHL12 PF14882.1 EMC80790.1 - 0.35 10.9 2.9 2.3 8.3 0.2 2.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 12 Pkinase PF00069.20 EMC80791.1 - 1.2e-73 247.4 0.0 1.6e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80791.1 - 1e-35 123.1 0.2 4.3e-35 121.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Tmemb_14 PF03647.8 EMC80792.1 - 3.7e-18 65.6 2.8 4.1e-18 65.5 1.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF308 PF03729.8 EMC80792.1 - 0.016 15.1 1.1 0.038 13.9 0.1 1.8 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF1212 PF06738.7 EMC80792.1 - 0.095 12.1 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) ETRAMP PF09716.5 EMC80792.1 - 1.8 8.5 4.1 5.5 7.0 0.1 2.7 1 1 2 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Branch PF02485.16 EMC80793.1 - 2.7e-54 183.9 0.0 4e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme TF_AP-2 PF03299.9 EMC80794.1 - 2.4e-68 229.7 0.0 2.8e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 FlhD PF05247.8 EMC80794.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) DUF4193 PF13834.1 EMC80795.1 - 1.3 9.2 4.1 0.81 9.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) DUF4653 PF15546.1 EMC80796.1 - 1.6e-23 83.2 1.2 1.9e-23 83.0 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) DNA_photolyase PF00875.13 EMC80796.1 - 0.079 12.7 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 DNA photolyase NYD-SP28 PF14772.1 EMC80796.1 - 0.11 12.6 3.0 0.18 11.8 2.1 1.3 1 0 0 1 1 1 0 Sperm tail UAA PF08449.6 EMC80797.1 - 9.7e-96 320.2 24.7 1.2e-95 319.9 17.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMC80797.1 - 0.0014 18.6 12.5 0.0014 18.6 8.6 3.1 2 1 0 3 3 3 2 EamA-like transporter family GST_C PF00043.20 EMC80798.1 - 3e-08 33.5 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC80798.1 - 3.6e-07 30.5 0.1 5.4e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC80798.1 - 7e-06 25.8 0.0 1.5e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Muted PF14942.1 EMC80799.1 - 1.4e-58 196.8 15.6 1.6e-58 196.7 10.8 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF148 PF02520.12 EMC80799.1 - 0.033 13.9 5.2 0.059 13.1 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 FliD_C PF07195.7 EMC80799.1 - 0.08 12.2 4.6 0.08 12.2 1.4 1.8 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus OmpH PF03938.9 EMC80799.1 - 0.12 12.2 8.5 0.16 11.9 5.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mitofilin PF09731.4 EMC80799.1 - 0.13 10.9 15.4 0.15 10.7 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GSH-S_N PF02951.9 EMC80799.1 - 0.13 12.0 1.7 0.2 11.4 1.2 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain AAA_11 PF13086.1 EMC80799.1 - 0.67 9.4 4.0 0.73 9.3 2.8 1.1 1 0 0 1 1 1 0 AAA domain Ax_dynein_light PF10211.4 EMC80799.1 - 1.8 8.3 14.7 2.3 8.0 10.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain UMPH-1 PF05822.7 EMC80799.1 - 3.5 6.8 6.7 5.8 6.1 4.6 1.4 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) PRP1_N PF06424.7 EMC80799.1 - 3.6 7.9 7.9 4.5 7.5 5.5 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Exonuc_VII_L PF02601.10 EMC80799.1 - 9.5 5.3 7.2 11 5.0 5.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Thioredoxin PF00085.15 EMC80800.1 - 4.8e-83 273.5 0.1 1.5e-30 104.9 0.0 3.0 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.1 EMC80800.1 - 1.2e-15 57.6 3.6 0.0015 18.6 0.0 5.3 3 3 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC80800.1 - 2e-11 43.8 1.3 0.019 15.0 0.0 4.9 3 3 3 6 6 6 3 Thioredoxin-like Thioredoxin_6 PF13848.1 EMC80800.1 - 9.4e-11 41.8 0.0 0.009 15.8 0.0 3.1 3 0 0 3 3 3 3 Thioredoxin-like domain HyaE PF07449.6 EMC80800.1 - 6.4e-06 26.0 0.0 0.029 14.2 0.0 3.2 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EMC80800.1 - 9.8e-06 25.5 1.5 0.67 10.0 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.1 EMC80800.1 - 0.0001 22.0 0.0 2.1 8.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_9 PF14595.1 EMC80800.1 - 0.00072 19.1 0.2 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.1 EMC80800.1 - 0.00077 19.0 0.0 3.7 6.9 0.0 3.5 3 1 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EMC80800.1 - 0.0016 18.4 0.3 12 5.8 0.0 4.2 3 2 2 5 5 5 0 Thioredoxin Redoxin PF08534.5 EMC80800.1 - 0.0024 17.4 0.8 1.5 8.3 0.0 2.6 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 EMC80800.1 - 0.0048 16.5 0.6 1.4 8.5 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family Mu-like_Com PF10122.4 EMC80800.1 - 2.2 7.4 6.4 29 3.7 0.4 3.3 3 0 0 3 3 3 0 Mu-like prophage protein Com TGF_beta PF00019.15 EMC80801.1 - 3.6e-44 149.3 1.7 3.6e-44 149.3 1.2 1.6 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC80801.1 - 5e-40 137.2 0.8 6.8e-40 136.8 0.0 1.5 2 0 0 2 2 2 1 TGF-beta propeptide YafO_toxin PF13957.1 EMC80801.1 - 0.023 14.5 0.3 0.18 11.6 0.0 2.4 3 0 0 3 3 3 0 Toxin YafO, type II toxin-antitoxin system RIO1 PF01163.17 EMC80802.1 - 4.8e-76 254.3 0.3 4.8e-76 254.3 0.2 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EMC80802.1 - 0.00076 19.2 0.0 0.012 15.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC80802.1 - 0.0051 15.9 0.4 0.12 11.3 0.3 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TRAP_alpha PF03896.11 EMC80803.1 - 2.2e-134 446.8 1.1 2.5e-134 446.7 0.8 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 EMC80803.1 - 5.7 6.9 8.6 11 5.9 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-H2C2_2 PF13465.1 EMC80804.1 - 2.4e-44 147.5 110.8 3.5e-08 33.3 0.9 20.0 20 0 0 20 20 20 9 Zinc-finger double domain zf-C2H2 PF00096.21 EMC80804.1 - 5.8e-44 145.8 124.6 5.4e-05 23.2 0.0 17.2 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80804.1 - 6.5e-29 98.1 121.0 4.4e-05 23.5 0.2 16.8 17 0 0 17 17 17 13 C2H2-type zinc finger zf-met PF12874.2 EMC80804.1 - 1.9e-11 43.7 75.9 0.013 15.6 0.3 13.2 13 0 0 13 13 13 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC80804.1 - 1.5e-07 31.3 65.4 0.072 13.2 1.1 13.6 15 0 0 15 15 15 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC80804.1 - 2.3e-05 24.3 3.3 0.0021 18.1 0.0 12.9 15 0 0 15 15 15 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EMC80804.1 - 0.00028 20.6 0.1 0.00028 20.6 0.1 14.1 16 0 0 16 16 16 5 C2H2-type zinc finger BolA PF01722.13 EMC80804.1 - 0.029 14.3 2.5 6.6 6.7 0.2 4.5 4 1 1 5 5 5 0 BolA-like protein E1_DerP2_DerF2 PF02221.10 EMC80806.1 - 2.4e-13 50.4 0.6 4.1e-13 49.7 0.2 1.5 1 1 1 2 2 2 1 ML domain Transglut_C PF00927.17 EMC80807.1 - 6e-38 129.1 0.4 1.1e-20 73.7 0.1 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 EMC80807.1 - 6.6e-36 122.9 0.0 1e-34 119.1 0.0 2.6 3 0 0 3 3 3 1 Transglutaminase family Transglut_core PF01841.14 EMC80807.1 - 1.4e-16 60.7 0.2 3e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF11 PF01345.13 EMC80807.1 - 0.0088 16.0 0.5 0.62 10.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF11 NRN1 PF15056.1 EMC80808.1 - 1.6e-25 88.8 0.4 1.9e-25 88.6 0.3 1.1 1 0 0 1 1 1 1 Neuritin protein family tRNA-synt_2d PF01409.15 EMC80809.1 - 4.2e-50 170.2 1.6 9.3e-31 106.8 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EMC80809.1 - 3.1e-22 78.5 0.0 1.1e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EMC80809.1 - 0.0079 15.0 0.3 2.1 7.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) ANKH PF07260.6 EMC80810.1 - 5.7e-199 660.2 5.2 5.7e-199 660.2 3.6 1.4 2 0 0 2 2 2 1 Progressive ankylosis protein (ANKH) TMCO5 PF14992.1 EMC80810.1 - 0.061 12.4 0.3 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 TMCO5 family UCR_Fe-S_N PF10399.4 EMC80810.1 - 1 8.5 0.0 1 8.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_C65 PF10275.4 EMC80811.1 - 5.3e-05 22.6 2.2 0.00045 19.6 1.4 2.0 1 1 0 1 1 1 1 Peptidase C65 Otubain Daxx PF03344.10 EMC80812.1 - 0.00017 20.2 32.0 0.00019 20.0 22.1 1.0 1 0 0 1 1 1 1 Daxx Family BUD22 PF09073.5 EMC80812.1 - 0.0044 16.1 24.4 0.0049 16.0 16.9 1.1 1 0 0 1 1 1 1 BUD22 AFT PF08731.6 EMC80812.1 - 0.049 13.8 1.6 0.057 13.6 1.1 1.3 1 0 0 1 1 1 0 Transcription factor AFT Nop14 PF04147.7 EMC80812.1 - 0.085 10.7 30.6 0.11 10.3 21.2 1.3 1 0 0 1 1 1 0 Nop14-like family Dala_Dala_lig_N PF01820.16 EMC80812.1 - 0.11 12.7 4.3 0.16 12.3 3.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Paf1 PF03985.8 EMC80812.1 - 0.12 11.1 30.9 0.14 10.8 21.4 1.1 1 0 0 1 1 1 0 Paf1 Plasmodium_Vir PF05795.6 EMC80812.1 - 0.13 11.4 5.9 0.16 11.1 4.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CENP-T PF15511.1 EMC80812.1 - 0.16 11.2 19.3 0.2 10.8 13.3 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 EMC80812.1 - 0.22 10.9 16.0 0.25 10.7 11.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FYDLN_acid PF09538.5 EMC80812.1 - 0.3 11.6 23.5 0.43 11.1 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Neur_chan_memb PF02932.11 EMC80812.1 - 0.56 10.0 4.5 0.66 9.8 3.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DARPP-32 PF05395.7 EMC80812.1 - 0.58 10.2 16.5 0.83 9.7 11.4 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF2722 PF10846.3 EMC80812.1 - 0.75 8.7 7.1 0.78 8.7 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1510 PF07423.6 EMC80812.1 - 0.96 8.7 21.7 1.4 8.2 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 EMC80812.1 - 1 8.0 11.1 1.2 7.7 7.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 EMC80812.1 - 1 9.0 8.3 1.1 8.9 5.7 1.2 1 0 0 1 1 1 0 DDHD domain GCD14 PF08704.5 EMC80812.1 - 1.2 8.5 3.9 1.5 8.2 2.7 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Zip PF02535.17 EMC80812.1 - 1.3 7.9 6.1 1.4 7.8 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cwf_Cwc_15 PF04889.7 EMC80812.1 - 1.4 8.5 22.1 1.9 8.1 15.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4246 PF14033.1 EMC80812.1 - 1.8 7.0 9.1 1.8 7.0 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF913 PF06025.7 EMC80812.1 - 2.3 6.9 3.9 2.2 6.9 2.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CobT PF06213.7 EMC80812.1 - 2.6 7.0 30.3 3.7 6.6 21.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.2 EMC80812.1 - 3.2 5.3 5.0 3.1 5.3 3.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.1 EMC80812.1 - 3.3 7.9 5.1 4.5 7.5 3.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SAPS PF04499.10 EMC80812.1 - 3.6 6.1 9.3 3.6 6.1 6.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cellulose_synt PF03552.9 EMC80812.1 - 3.7 5.7 4.4 4.3 5.5 3.1 1.0 1 0 0 1 1 1 0 Cellulose synthase eIF-3c_N PF05470.7 EMC80812.1 - 3.9 5.4 15.4 4.4 5.2 10.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sec62 PF03839.11 EMC80812.1 - 3.9 6.8 8.1 4.4 6.6 5.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DDRGK PF09756.4 EMC80812.1 - 4 6.8 31.7 5 6.4 22.0 1.1 1 0 0 1 1 1 0 DDRGK domain SpoIIIAH PF12685.2 EMC80812.1 - 5.1 6.5 12.9 6.4 6.2 8.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Adeno_terminal PF02459.10 EMC80812.1 - 5.6 4.9 18.3 6.2 4.8 12.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein NPR3 PF03666.8 EMC80812.1 - 5.8 5.3 10.0 6.9 5.0 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FGF-BP1 PF06473.7 EMC80812.1 - 7.2 6.1 8.7 8.8 5.8 6.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) IFT57 PF10498.4 EMC80812.1 - 8.4 5.0 15.5 11 4.6 10.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RRM_1 PF00076.17 EMC80813.1 - 8.9e-17 60.4 0.1 1.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC80813.1 - 3.7e-11 42.6 0.0 7.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC80813.1 - 5.3e-11 42.3 0.0 7.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_22 PF03901.12 EMC80814.1 - 2.3e-51 175.1 26.7 3.3e-51 174.6 18.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Transferrin PF00405.12 EMC80815.1 - 4.9e-225 745.4 10.6 3.1e-119 397.7 0.6 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.2 EMC80815.1 - 5.1e-16 58.7 0.0 7.5e-07 28.7 0.0 2.5 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3421 PF11901.3 EMC80815.1 - 0.0044 16.7 0.0 0.33 10.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3421) SBP_bac_3 PF00497.15 EMC80815.1 - 0.009 15.2 0.2 5 6.3 0.0 2.8 2 1 1 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 PDZ PF00595.19 EMC80816.1 - 3.3e-63 209.8 8.2 1.9e-20 72.7 0.1 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 EMC80816.1 - 1.7e-57 193.8 0.3 2.8e-57 193.1 0.2 1.4 1 0 0 1 1 1 1 Guanylate kinase MAGUK_N_PEST PF10608.4 EMC80816.1 - 1.1e-44 150.7 5.2 3.7e-44 149.0 3.6 2.0 1 0 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc PF10600.4 EMC80816.1 - 5.6e-31 106.6 5.2 2.7e-30 104.4 3.6 2.3 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.1 EMC80816.1 - 2.4e-18 65.7 3.5 2.1e-05 24.3 0.1 4.0 4 0 0 4 4 4 3 PDZ domain SH3_1 PF00018.23 EMC80816.1 - 2.5e-08 33.1 0.1 6.9e-08 31.7 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC80816.1 - 2.9e-08 33.0 0.0 7.8e-08 31.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC80816.1 - 0.00047 19.6 0.2 0.0028 17.2 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain L27_1 PF09058.5 EMC80816.1 - 0.0006 19.6 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 L27_1 adh_short PF00106.20 EMC80817.1 - 6.2e-25 88.0 0.0 8e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC80817.1 - 1.3e-07 31.4 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC80817.1 - 2.2e-07 30.8 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMC80817.1 - 9.8e-07 28.1 0.0 5.4e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMC80817.1 - 0.0063 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMC80817.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMC80818.1 - 8.2e-20 71.3 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC80818.1 - 1.1e-06 28.5 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC80818.1 - 0.0031 17.1 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Lipocalin_2 PF08212.7 EMC80819.1 - 2e-24 86.0 0.0 2.8e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 EMC80819.1 - 5.9e-23 81.4 0.1 6.7e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 EMC80819.1 - 9.6e-05 22.0 0.3 0.0003 20.4 0.2 1.8 1 1 0 1 1 1 1 Triabin VDE PF07137.6 EMC80819.1 - 0.033 14.0 0.0 0.046 13.5 0.0 1.4 1 1 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) HeH PF12949.2 EMC80819.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 HeH/LEM domain IPP-2 PF04979.9 EMC80820.1 - 1.4e-52 177.3 14.2 1.5e-52 177.3 9.5 1.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3435 PF11917.3 EMC80820.1 - 0.13 10.9 5.8 0.15 10.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) CDC27 PF09507.5 EMC80820.1 - 1.1 8.3 20.0 1.4 8.0 13.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM60A PF15396.1 EMC80820.1 - 2.8 7.6 5.4 3.5 7.3 3.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Rrp15p PF07890.7 EMC80820.1 - 8.4 6.4 12.7 17 5.4 8.8 1.6 1 1 0 1 1 1 0 Rrp15p ArfGap PF01412.13 EMC80821.1 - 2.3e-41 140.2 0.1 2.3e-41 140.2 0.1 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EMC80821.1 - 3.1e-20 72.2 1.0 2.2e-13 50.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC80821.1 - 9.2e-14 50.4 0.6 2e-05 24.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 EMC80821.1 - 2.8e-13 49.9 0.6 7e-13 48.6 0.4 1.7 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.1 EMC80821.1 - 4.6e-11 42.5 0.3 4.1e-07 30.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC80821.1 - 8.2e-10 38.9 0.3 0.0044 17.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80821.1 - 1.3e-05 24.9 0.9 0.094 13.0 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat PH_11 PF15413.1 EMC80821.1 - 2.8e-05 24.3 8.1 6.4e-05 23.1 1.6 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PID_2 PF14719.1 EMC80822.1 - 1.2e-63 214.0 0.9 1.5e-63 213.7 0.6 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.18 EMC80822.1 - 7.3e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MMR_HSR1 PF01926.18 EMC80823.1 - 6.5e-16 58.3 0.1 4.3e-13 49.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC80823.1 - 5e-06 25.8 0.1 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EMC80823.1 - 0.00044 19.4 0.1 0.0014 17.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMC80823.1 - 0.00069 18.7 0.0 0.0019 17.3 0.0 1.8 1 0 0 1 1 1 1 AIG1 family cobW PF02492.14 EMC80823.1 - 0.055 12.9 0.3 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EMC80823.1 - 0.093 13.2 0.0 0.42 11.1 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein Ctr PF04145.10 EMC80823.1 - 0.27 11.2 1.1 9.8 6.2 0.1 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Dynamin_N PF00350.18 EMC80823.1 - 6.2 6.6 9.4 3.3 7.5 0.2 3.5 3 1 1 4 4 4 0 Dynamin family E1-E2_ATPase PF00122.15 EMC80824.1 - 2.1e-32 111.9 1.0 3.9e-32 111.1 0.7 1.4 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 EMC80824.1 - 5.4e-24 84.3 0.4 1.2e-23 83.2 0.1 1.8 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 EMC80824.1 - 2.4e-17 63.7 0.0 6.5e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC80824.1 - 4e-15 56.8 0.4 1.3e-12 48.5 0.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC80824.1 - 6.7e-07 29.1 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMC80824.1 - 1.5e-06 27.5 0.0 3.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF342 PF03961.8 EMC80824.1 - 0.018 13.5 0.0 0.027 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ets PF00178.17 EMC80825.1 - 1.5e-31 108.3 4.4 8.6e-31 105.9 0.7 2.4 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 EMC80825.1 - 5.8e-25 86.8 3.3 8.3e-25 86.3 1.7 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Luteo_Vpg PF01659.11 EMC80825.1 - 0.0054 16.4 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Luteovirus putative VPg genome linked protein Acetyltransf_2 PF00797.12 EMC80825.1 - 0.056 13.0 0.1 0.25 10.8 0.1 2.0 1 1 0 1 1 1 0 N-acetyltransferase Aldolase_II PF00596.16 EMC80826.1 - 3.3e-44 150.6 0.0 3.9e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-oxoacid_dh PF00198.18 EMC80827.1 - 3.9e-78 261.8 0.4 5.2e-78 261.4 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMC80827.1 - 3.9e-21 74.4 0.2 1e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EMC80827.1 - 1.4e-11 43.7 0.0 3.7e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EMC80827.1 - 8.4e-05 22.1 0.0 0.035 13.7 0.0 3.1 1 1 1 2 2 2 2 Biotin-lipoyl like QRPTase_N PF02749.11 EMC80827.1 - 0.043 13.6 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD PF00529.15 EMC80827.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 EMC80827.1 - 0.089 11.9 0.0 0.37 9.8 0.0 1.8 1 1 1 2 2 2 0 HlyD family secretion protein Xlink PF00193.12 EMC80828.1 - 5.1e-23 80.9 0.7 8.8e-23 80.2 0.1 1.7 2 0 0 2 2 2 1 Extracellular link domain PBP-Tp47_a PF14889.1 EMC80828.1 - 0.027 13.8 0.1 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a SDF PF00375.13 EMC80829.1 - 5.6e-136 453.3 27.9 6.6e-136 453.1 19.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Trypsin PF00089.21 EMC80830.1 - 1.3e-35 122.9 0.0 1.8e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 EMC80830.1 - 6.9e-24 84.0 0.0 1.7e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 CUB domain Sushi PF00084.15 EMC80830.1 - 9.2e-15 54.7 2.3 8.1e-09 35.7 0.2 3.6 4 0 0 4 4 4 2 Sushi domain (SCR repeat) EGF PF00008.22 EMC80830.1 - 3.1e-07 30.2 3.3 3.1e-07 30.2 2.3 3.7 5 0 0 5 5 5 1 EGF-like domain DUF1986 PF09342.6 EMC80830.1 - 0.00024 20.5 0.2 0.00024 20.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) EGF_2 PF07974.8 EMC80830.1 - 0.0016 18.5 5.8 0.0016 18.5 4.0 4.6 5 0 0 5 5 5 1 EGF-like domain hEGF PF12661.2 EMC80830.1 - 0.03 14.3 1.3 0.03 14.3 0.9 4.8 4 0 0 4 4 4 0 Human growth factor-like EGF cEGF PF12662.2 EMC80830.1 - 9 6.0 22.3 0.033 13.8 2.1 5.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like HCaRG PF07258.9 EMC80832.1 - 5.1e-30 104.3 0.1 6.6e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 HCaRG protein HbrB PF08539.6 EMC80833.1 - 1.3e-28 99.7 0.8 8.3e-27 93.9 0.5 2.3 1 1 0 1 1 1 1 HbrB-like zf-TRAF PF02176.13 EMC80834.1 - 1.2e-28 99.2 27.8 2.3e-18 66.3 2.3 3.9 2 1 1 3 3 3 3 TRAF-type zinc finger MATH PF00917.21 EMC80834.1 - 4e-24 85.1 0.0 9e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.1 EMC80834.1 - 2.4e-10 40.2 5.7 2.4e-10 40.2 4.0 3.9 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC80834.1 - 7.5e-09 35.2 4.2 7.5e-09 35.2 2.9 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EMC80834.1 - 1.6e-08 34.0 4.9 1.6e-08 34.0 3.4 4.2 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC80834.1 - 1.2e-06 28.0 4.3 1.2e-06 28.0 3.0 4.1 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC80834.1 - 2.7e-06 27.1 4.5 2.7e-06 27.1 3.1 3.9 2 1 2 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMC80834.1 - 4e-05 23.2 4.2 4e-05 23.2 2.9 4.2 2 1 2 4 4 2 1 zinc-RING finger domain SlyX PF04102.7 EMC80834.1 - 0.00041 20.6 2.9 0.00041 20.6 2.0 2.1 2 0 0 2 2 2 1 SlyX PspA_IM30 PF04012.7 EMC80834.1 - 0.00064 19.1 0.9 0.0018 17.7 0.6 1.8 1 0 0 1 1 1 1 PspA/IM30 family Med21 PF11221.3 EMC80834.1 - 0.002 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Sina PF03145.11 EMC80834.1 - 0.0022 17.6 20.3 0.017 14.7 4.0 3.4 1 1 2 3 3 3 2 Seven in absentia protein family Spc7 PF08317.6 EMC80834.1 - 0.0056 15.3 0.1 0.0091 14.6 0.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-RING_UBOX PF13445.1 EMC80834.1 - 0.012 15.2 6.1 0.012 15.2 4.2 2.4 2 0 0 2 2 1 0 RING-type zinc-finger CENP-F_leu_zip PF10473.4 EMC80834.1 - 0.018 14.8 0.9 0.052 13.4 0.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EMC80834.1 - 0.019 14.7 0.4 0.033 13.9 0.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EMC80834.1 - 0.02 12.6 1.6 0.03 12.0 1.1 1.2 1 0 0 1 1 1 0 Myosin tail Tropomyosin_1 PF12718.2 EMC80834.1 - 0.027 14.3 1.5 0.048 13.5 1.1 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF4455 PF14643.1 EMC80834.1 - 0.029 13.0 0.6 0.044 12.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Synaphin PF05835.7 EMC80834.1 - 0.03 14.4 0.6 0.063 13.4 0.4 1.5 1 0 0 1 1 1 0 Synaphin protein TMF_DNA_bd PF12329.3 EMC80834.1 - 0.05 13.4 2.9 0.095 12.5 2.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding U-box PF04564.10 EMC80834.1 - 0.051 13.5 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 1 0 U-box domain TSC22 PF01166.13 EMC80834.1 - 0.074 13.0 1.1 5.5 7.0 0.1 3.1 1 1 1 2 2 2 0 TSC-22/dip/bun family AAA_13 PF13166.1 EMC80834.1 - 0.1 11.0 0.5 0.16 10.4 0.3 1.2 1 0 0 1 1 1 0 AAA domain DM PF00751.13 EMC80834.1 - 0.13 11.7 18.5 0.31 10.6 2.3 3.9 1 1 2 3 3 3 0 DM DNA binding domain DUF1664 PF07889.7 EMC80834.1 - 0.22 11.3 1.4 0.59 9.9 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RAG1 PF12940.2 EMC80835.1 - 1.5e-236 784.8 0.1 2.3e-236 784.2 0.1 1.3 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) zf-RAG1 PF10426.4 EMC80835.1 - 1.2e-16 60.3 2.9 1.2e-16 60.3 2.0 3.5 3 0 0 3 3 3 1 Recombination-activating protein 1 zinc-finger domain zf-C3HC4 PF00097.20 EMC80835.1 - 5.2e-07 29.2 14.6 5.2e-07 29.2 10.1 3.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC80835.1 - 8.7e-06 25.6 15.0 8.7e-06 25.6 10.4 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMC80835.1 - 9e-05 22.1 8.6 9e-05 22.1 6.0 2.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EMC80835.1 - 0.0038 17.0 13.6 0.0038 17.0 9.5 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC80835.1 - 0.026 14.2 8.8 0.093 12.4 6.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger RAG2 PF03089.9 EMC80836.1 - 3e-176 585.1 0.0 3.8e-176 584.7 0.0 1.1 1 0 0 1 1 1 1 Recombination activating protein 2 RAG2_PHD PF13341.1 EMC80836.1 - 1.3e-44 150.0 2.3 2.8e-44 148.9 1.6 1.6 1 0 0 1 1 1 1 RAG2 PHD domain Kelch_3 PF13415.1 EMC80836.1 - 4.2e-10 39.5 0.0 2.2e-05 24.4 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC80836.1 - 4.3e-06 26.5 0.3 0.24 11.3 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 EMC80836.1 - 3.8e-05 23.3 0.4 9.1 6.1 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain PHD PF00628.24 EMC80836.1 - 0.0034 17.0 1.6 0.0073 15.9 0.1 2.3 2 0 0 2 2 2 1 PHD-finger TRAPPC-Trs85 PF12739.2 EMC80837.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TLV_coat PF00429.14 EMC80838.1 - 2.1e-109 366.5 0.7 2.6e-109 366.2 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Lipoprotein_20 PF13942.1 EMC80838.1 - 0.04 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 YfhG lipoprotein BLOC1_2 PF10046.4 EMC80838.1 - 0.099 12.7 0.9 0.53 10.4 0.0 2.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EMC80838.1 - 0.16 11.5 3.3 0.61 9.6 0.1 2.1 2 0 0 2 2 2 0 IncA protein LRR_8 PF13855.1 EMC80839.1 - 8.5e-44 147.1 23.9 3.4e-12 45.9 0.2 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EMC80839.1 - 3.6e-24 83.9 28.3 5.5e-08 32.2 0.7 5.7 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC80839.1 - 4.7e-22 78.0 0.0 2.9e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC80839.1 - 8.1e-18 61.7 31.4 0.024 14.6 0.0 10.3 10 0 0 10 10 10 6 Leucine Rich Repeat I-set PF07679.11 EMC80839.1 - 5.1e-14 51.8 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 EMC80839.1 - 8.6e-08 32.0 0.1 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC80839.1 - 1.2e-07 31.7 0.2 1.2e-07 31.7 0.1 1.8 2 0 0 2 2 1 1 Immunoglobulin domain LRR_7 PF13504.1 EMC80839.1 - 1.7e-06 27.2 30.0 1.5 9.3 0.0 9.2 9 0 0 9 9 9 4 Leucine rich repeat ig PF00047.20 EMC80839.1 - 1.5e-05 25.0 0.1 1.5e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.1 EMC80839.1 - 0.00015 21.3 5.1 0.0049 16.4 0.3 2.8 1 1 2 3 3 3 1 Leucine-rich repeat Ig_3 PF13927.1 EMC80839.1 - 0.00018 21.9 6.7 0.00046 20.6 0.3 3.7 2 2 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.11 EMC80839.1 - 0.0026 16.1 3.5 0.029 12.6 0.4 2.3 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E gpUL132 PF11359.3 EMC80839.1 - 0.0031 16.9 1.2 0.0052 16.1 0.4 1.6 1 1 0 1 1 1 1 Glycoprotein UL132 LRR_6 PF13516.1 EMC80839.1 - 0.026 14.5 24.0 11 6.4 0.2 7.6 6 2 2 8 8 8 0 Leucine Rich repeat Syndecan PF01034.15 EMC80839.1 - 0.21 11.2 0.4 0.42 10.3 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain API5 PF05918.6 EMC80840.1 - 3.8e-120 402.0 15.1 1.8e-119 399.7 10.4 2.0 1 1 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 EMC80840.1 - 3.5e-05 23.9 0.3 0.00026 21.2 0.2 2.3 1 1 0 2 2 2 1 HEAT repeats MMS19_N PF14500.1 EMC80840.1 - 0.012 14.9 3.0 0.065 12.4 2.1 2.1 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF2435 PF10363.4 EMC80840.1 - 0.013 15.4 0.2 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Dak2 PF02734.12 EMC80840.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 DAK2 domain InvH PF04741.7 EMC80840.1 - 0.07 12.9 0.8 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 InvH outer membrane lipoprotein adh_short PF00106.20 EMC80841.1 - 4.6e-18 65.6 0.0 8.4e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMC80841.1 - 1e-06 28.5 0.0 0.0014 18.3 0.0 2.1 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EMC80841.1 - 9.8e-06 25.6 0.1 1.8e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC80841.1 - 0.025 14.0 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMC80841.1 - 0.046 13.4 0.5 7.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Wax2_C PF12076.3 EMC80841.1 - 0.061 13.0 0.1 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain Saccharop_dh PF03435.13 EMC80841.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Adenylsucc_synt PF00709.16 EMC80841.1 - 0.13 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase 2OG-FeII_Oxy_2 PF13532.1 EMC80842.1 - 2.1e-33 115.8 0.1 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMC80842.1 - 4.2e-05 23.7 0.0 6.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.16 EMC80843.1 - 3.1e-59 200.7 0.0 5.8e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMC80843.1 - 0.00076 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2405 PF10293.4 EMC80843.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Glyco_transf_64 PF09258.5 EMC80844.1 - 1.4e-95 319.1 0.2 2e-95 318.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 EMC80844.1 - 2.8e-57 194.0 0.0 3.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Exostosin family DUF2387 PF09526.5 EMC80844.1 - 0.071 13.0 0.2 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Fumble PF03630.9 EMC80844.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fumble Tetraspannin PF00335.15 EMC80845.1 - 1.1e-45 155.6 13.7 2.4e-45 154.4 9.5 1.5 1 1 0 1 1 1 1 Tetraspanin family GATase_5 PF13507.1 EMC80845.1 - 0.0054 15.6 0.0 0.0073 15.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Claudin_2 PF13903.1 EMC80845.1 - 9.3 5.9 8.8 9.3 5.8 4.2 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 EMC80846.1 - 1.7e-49 168.0 16.7 8.1e-49 165.8 11.5 1.8 1 1 0 1 1 1 1 Tetraspanin family SUR7 PF06687.7 EMC80846.1 - 2.8 7.4 17.4 0.059 12.9 4.6 2.6 3 0 0 3 3 3 0 SUR7/PalI family DUF872 PF05915.7 EMC80846.1 - 9.7 6.0 11.1 7 6.5 0.5 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) p53-inducible11 PF14936.1 EMC80847.1 - 2.2e-98 327.4 1.3 2.5e-98 327.2 0.9 1.0 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF3483 PF11982.3 EMC80847.1 - 0.011 15.0 0.3 0.017 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) SET PF00856.23 EMC80848.1 - 0.00086 19.6 1.0 0.0065 16.7 0.0 2.7 2 1 0 2 2 2 1 SET domain TRM PF02005.11 EMC80848.1 - 0.015 14.2 0.5 0.023 13.6 0.3 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase C2 PF00168.25 EMC80851.1 - 7e-22 77.0 0.0 7.6e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 EMC80851.1 - 0.0001 22.1 0.1 0.036 13.8 0.0 2.9 2 1 1 3 3 3 2 Phosphoinositide 3-kinase C2 LRR_8 PF13855.1 EMC80853.1 - 5.7e-54 179.7 58.3 1.6e-11 43.8 0.3 6.8 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 EMC80853.1 - 6.1e-22 76.7 35.7 0.00075 19.0 0.0 8.8 3 2 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC80853.1 - 1.6e-16 57.7 29.1 0.38 10.9 0.0 12.9 13 0 0 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC80853.1 - 0.016 15.2 34.5 3.1 8.3 0.1 11.3 12 0 0 12 12 12 0 Leucine rich repeat LRR_9 PF14580.1 EMC80853.1 - 0.38 10.2 11.4 0.66 9.5 1.1 3.5 2 2 2 4 4 4 0 Leucine-rich repeat LRRNT PF01462.13 EMC80853.1 - 0.85 9.1 17.6 0.025 14.0 2.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Actin PF00022.14 EMC80854.1 - 2e-79 266.8 0.0 2.5e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Actin Chorein_N PF12624.2 EMC80855.1 - 2e-12 46.7 0.0 2.5e-11 43.1 0.0 2.6 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ank_2 PF12796.2 EMC80856.1 - 2.9e-66 219.8 12.8 3.5e-18 65.7 0.2 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMC80856.1 - 7.8e-45 148.5 6.3 5.8e-07 29.0 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EMC80856.1 - 7.9e-43 143.5 7.0 2.9e-09 36.8 0.1 6.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80856.1 - 7.7e-38 124.7 3.2 9.3e-07 28.5 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EMC80856.1 - 8.9e-36 121.6 4.6 8.2e-09 35.7 0.1 5.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) SAM_1 PF00536.25 EMC80856.1 - 1.6e-26 92.2 0.0 3.3e-15 56.0 0.0 2.9 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC80856.1 - 2.8e-23 81.5 0.2 3.2e-15 55.7 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) pRN1_helical PF13010.1 EMC80856.1 - 0.13 11.8 0.1 1.1 8.9 0.0 2.4 3 0 0 3 3 3 0 Primase helical domain WD40 PF00400.27 EMC80857.1 - 4.9e-84 273.5 41.9 2.8e-10 39.6 0.1 13.9 14 0 0 14 14 14 11 WD domain, G-beta repeat NB-ARC PF00931.17 EMC80857.1 - 4.8e-64 215.9 0.1 7.9e-64 215.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain CARD PF00619.16 EMC80857.1 - 4.2e-17 61.7 1.4 4.2e-17 61.7 1.0 2.1 2 0 0 2 2 2 1 Caspase recruitment domain Nup160 PF11715.3 EMC80857.1 - 8.9e-07 27.4 14.1 0.039 12.0 0.5 6.0 3 2 1 5 5 5 3 Nucleoporin Nup120/160 AAA_16 PF13191.1 EMC80857.1 - 0.0036 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC80857.1 - 0.0055 16.8 0.0 0.025 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF2415 PF10313.4 EMC80857.1 - 0.0082 15.8 0.1 0.12 12.0 0.0 3.1 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) Apc4_WD40 PF12894.2 EMC80857.1 - 0.017 14.6 0.1 1.9 8.0 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.4 EMC80857.1 - 0.19 11.0 0.3 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature IncA PF04156.9 EMC80858.1 - 0.0018 17.9 2.4 0.0018 17.9 1.6 3.1 1 1 1 3 3 3 1 IncA protein MHC2-interact PF09307.5 EMC80858.1 - 0.0026 17.5 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 CLIP, MHC2 interacting Sec8_exocyst PF04048.9 EMC80858.1 - 0.0036 16.9 1.1 0.0036 16.9 0.8 3.1 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain DUF4200 PF13863.1 EMC80858.1 - 0.013 15.4 16.6 0.036 13.9 0.3 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) DUF4446 PF14584.1 EMC80858.1 - 0.028 14.2 13.5 1.5 8.6 0.2 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF4446) COG5 PF10392.4 EMC80858.1 - 0.045 13.6 14.8 0.9 9.5 1.6 4.0 1 1 4 5 5 5 0 Golgi transport complex subunit 5 NPV_P10 PF05531.7 EMC80858.1 - 0.083 13.1 18.0 0.61 10.3 0.8 4.7 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EMC80858.1 - 0.1 11.7 14.8 0.31 10.1 2.5 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2400 PF09674.5 EMC80858.1 - 1.8 8.2 8.9 0.2 11.3 2.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) V_ATPase_I PF01496.14 EMC80858.1 - 3.8 5.2 17.7 1.6 6.5 2.6 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 EMC80858.1 - 3.9 6.9 12.6 0.6 9.5 0.4 3.0 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like DASH_Dam1 PF08653.5 EMC80858.1 - 4.7 7.0 7.3 25 4.7 0.0 4.1 5 0 0 5 5 5 0 DASH complex subunit Dam1 DUF972 PF06156.8 EMC80858.1 - 6.3 7.1 19.5 2.3 8.6 1.2 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF972) MCPsignal PF00015.16 EMC80858.1 - 7.4 6.0 15.6 14 5.1 5.7 3.1 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mito_carr PF00153.22 EMC80859.1 - 2.9e-47 158.3 7.4 1.9e-19 69.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PTR2 PF00854.16 EMC80859.1 - 0.037 12.8 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 POT family LEM PF03020.10 EMC80860.1 - 3.9e-21 74.2 0.7 8.7e-21 73.1 0.5 1.6 1 0 0 1 1 1 1 LEM domain DUF912 PF06024.7 EMC80860.1 - 0.14 12.2 0.6 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FlaC_arch PF05377.6 EMC80862.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) End3 PF12761.2 EMC80862.1 - 0.13 11.8 1.0 0.19 11.3 0.7 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Mod_r PF07200.8 EMC80862.1 - 0.32 10.9 4.3 0.63 9.9 3.0 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4486 PF14858.1 EMC80863.1 - 4.2e-251 833.9 8.3 5e-251 833.6 5.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) Pkinase PF00069.20 EMC80864.1 - 3.9e-74 249.0 0.0 7.9e-74 248.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80864.1 - 5.6e-35 120.6 0.0 1.2e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC80864.1 - 3.7e-07 29.3 0.0 6.3e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC80864.1 - 0.0007 18.7 0.1 0.002 17.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC80864.1 - 0.039 13.2 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 EMC80864.1 - 0.046 12.5 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMC80864.1 - 0.049 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ets PF00178.17 EMC80865.1 - 5.1e-38 129.0 3.2 7.8e-38 128.4 2.2 1.3 1 0 0 1 1 1 1 Ets-domain Lyase_aromatic PF00221.14 EMC80866.1 - 2.9e-188 626.1 0.0 3.4e-188 625.9 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase DUF3534 PF12053.3 EMC80866.1 - 0.00037 20.3 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3534) Amidohydro_4 PF13147.1 EMC80867.1 - 3.6e-23 82.9 2.3 2.3e-22 80.3 1.6 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC80867.1 - 4.2e-15 55.8 0.2 4.9e-11 42.4 0.0 2.9 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 EMC80867.1 - 1.9e-14 54.0 0.8 1.6e-09 37.8 0.1 2.3 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMC80867.1 - 3.6e-12 45.9 0.0 9.7e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EMC80867.1 - 0.017 14.0 0.1 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase LSM PF01423.17 EMC80868.1 - 0.00029 20.3 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain UCH PF00443.24 EMC80869.1 - 6.2e-62 209.1 1.5 1.2e-61 208.1 1.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC80869.1 - 6.4e-20 71.0 8.8 6.4e-20 71.0 6.1 3.3 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC80869.1 - 1.1e-17 64.4 4.4 4.3e-13 49.3 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ArfGap PF01412.13 EMC80869.1 - 0.084 12.6 5.7 0.14 11.9 2.6 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Peptidase_M24 PF00557.19 EMC80870.1 - 6.5e-49 166.3 0.0 8.6e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PT PF04886.7 EMC80873.1 - 0.0001 21.5 0.3 0.014 14.7 0.0 3.2 2 1 1 3 3 3 3 PT repeat 7tm_1 PF00001.16 EMC80874.1 - 1e-25 90.3 3.5 1.2e-25 90.1 2.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC80874.1 - 1.7e-06 27.3 0.9 2.1e-06 27.1 0.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cornichon PF03311.9 EMC80875.1 - 1.8e-34 118.5 7.4 1.2e-26 93.3 2.1 2.1 2 0 0 2 2 2 2 Cornichon protein Cofilin_ADF PF00241.15 EMC80876.1 - 7.2e-24 84.0 0.1 2.1e-23 82.5 0.1 1.6 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNA_pol_Rpb2_4 PF04566.8 EMC80876.1 - 0.085 12.6 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 GTP_cyclohydroI PF01227.17 EMC80877.1 - 1.9e-63 212.9 0.4 2.3e-63 212.7 0.3 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EMC80877.1 - 0.00029 20.7 0.0 0.00052 19.8 0.0 1.5 1 1 0 1 1 1 1 QueF-like protein MAPKK1_Int PF08923.5 EMC80877.1 - 0.043 13.4 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting HMG_box PF00505.14 EMC80878.1 - 1.8e-08 34.5 0.9 4e-08 33.4 0.1 2.0 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC80878.1 - 0.00095 19.4 0.2 0.00095 19.4 0.2 2.7 2 1 1 3 3 3 1 HMG-box domain DUF3534 PF12053.3 EMC80878.1 - 0.025 14.4 0.1 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) TUG-UBL1 PF11470.3 EMC80878.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG SspP PF08179.7 EMC80878.1 - 0.3 11.3 5.8 8.8 6.6 0.1 2.7 2 0 0 2 2 2 0 Small acid-soluble spore protein P family WD40 PF00400.27 EMC80879.1 - 3.4e-27 93.2 7.3 4.6e-10 38.9 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3639 PF12341.3 EMC80879.1 - 1.9e-11 43.7 0.0 4.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EMC80879.1 - 3.9e-07 29.9 0.0 5.4e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC80879.1 - 0.034 12.3 0.1 0.16 10.1 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SOCS PF12610.3 EMC80880.1 - 1e-18 67.3 3.7 1e-18 67.3 2.5 2.3 2 0 0 2 2 2 1 Suppressor of cytokine signalling SOCS_box PF07525.11 EMC80880.1 - 1.1e-12 47.6 0.1 2e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 EMC80880.1 - 3.4e-08 33.1 0.0 9.1e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Gal-bind_lectin PF00337.17 EMC80882.1 - 4e-37 126.5 0.0 5.1e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin F-box-like PF12937.2 EMC80883.1 - 0.00078 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC80883.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 F-box domain Pkinase_Tyr PF07714.12 EMC80884.1 - 7.7e-64 215.2 0.0 1.3e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC80884.1 - 3.4e-59 200.0 0.0 7.2e-59 199.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.25 EMC80884.1 - 2.4e-10 40.4 4.7 8e-10 38.7 0.3 3.3 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC80884.1 - 2.5e-09 36.8 0.2 7.1e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC80884.1 - 0.0057 16.3 0.2 0.019 14.7 0.1 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sugarporin_N PF11471.3 EMC80884.1 - 2.9 7.6 7.9 5.7 6.6 5.5 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension RasGEF PF00617.14 EMC80885.1 - 2e-69 233.1 2.9 3.7e-69 232.2 2.0 1.5 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.24 EMC80885.1 - 3.4e-28 97.2 0.0 1.9e-17 62.8 0.0 3.4 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DEP PF00610.16 EMC80885.1 - 1.2e-22 79.3 1.9 2.5e-22 78.3 0.5 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.15 EMC80885.1 - 6.8e-13 48.6 0.1 2.9e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif RA PF00788.18 EMC80885.1 - 3.8e-05 24.0 0.0 0.00012 22.5 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF2360 PF10152.4 EMC80886.1 - 0.071 13.3 4.0 0.11 12.7 2.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 EMC80886.1 - 0.3 10.4 10.4 0.31 10.4 7.2 1.1 1 0 0 1 1 1 0 Vta1 like RhoGEF PF00621.15 EMC80888.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain DUF4655 PF15548.1 EMC80888.1 - 0.061 12.2 0.1 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) Peptidase_M14 PF00246.19 EMC80889.1 - 1.2e-84 284.1 0.3 2.6e-84 283.1 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMC80889.1 - 3.7e-14 52.1 0.2 9.4e-14 50.8 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide PDDEXK_3 PF13366.1 EMC80889.1 - 0.15 12.1 0.1 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Sulfotransfer_1 PF00685.22 EMC80891.1 - 5.5e-86 288.1 0.0 6.3e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC80891.1 - 1.4e-05 26.1 0.0 2.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 EMC80891.1 - 0.0013 18.2 0.1 1.9 7.9 0.0 2.5 3 0 0 3 3 3 2 Stf0 sulphotransferase UDPGT PF00201.13 EMC80892.1 - 7.6e-220 730.6 0.0 8.9e-220 730.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMC80892.1 - 4.8e-06 26.3 0.0 8.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EMC80892.1 - 0.00015 21.0 0.2 0.0016 17.6 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 1 Glyco_trans_4_4 PF13579.1 EMC80892.1 - 0.0091 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_28 PF03033.15 EMC80892.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Prominin PF05478.6 EMC80892.1 - 0.14 9.6 3.2 0.2 9.1 2.3 1.2 1 0 0 1 1 1 0 Prominin YTH PF04146.10 EMC80893.1 - 5.1e-42 142.7 0.0 8.2e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Trypsin PF00089.21 EMC80894.1 - 9.9e-72 241.0 0.4 1.1e-71 240.9 0.3 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC80894.1 - 8.4e-09 35.1 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC80894.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 EMC80894.1 - 0.0094 15.3 0.0 0.04 13.2 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF316) Trypsin PF00089.21 EMC80895.1 - 6.5e-51 173.0 0.0 7.5e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin ThiF PF00899.16 EMC80896.1 - 2e-48 163.6 0.0 1.5e-31 109.0 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EMC80896.1 - 3e-32 110.0 0.6 8.4e-26 89.3 0.1 2.9 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EMC80896.1 - 1.4e-28 99.6 0.0 2.9e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EMC80896.1 - 1.7e-23 81.6 2.0 1.3e-20 72.5 0.5 2.7 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Latrophilin PF02354.11 EMC80897.1 - 5.8e-131 436.5 23.1 8e-104 347.2 5.6 2.2 1 1 1 2 2 2 2 Latrophilin Cytoplasmic C-terminal region OLF PF02191.11 EMC80897.1 - 2.2e-95 318.6 1.6 9.9e-95 316.5 1.8 1.6 2 0 0 2 2 2 1 Olfactomedin-like domain DUF3497 PF12003.3 EMC80897.1 - 4.1e-83 278.0 7.0 6e-83 277.4 4.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) 7tm_2 PF00002.19 EMC80897.1 - 1.1e-70 237.5 22.1 1.7e-70 236.8 15.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 EMC80897.1 - 1.5e-15 57.0 9.0 3.2e-15 55.9 6.2 1.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 EMC80897.1 - 1.3e-06 28.3 0.5 3.2e-06 27.0 0.3 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 EMC80897.1 - 0.0097 14.8 17.7 0.017 14.0 12.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pax2_C PF12403.3 EMC80898.1 - 4.8e-17 61.6 3.8 1.1e-16 60.5 2.7 1.6 1 0 0 1 1 1 1 Paired-box protein 2 C terminal Pkinase PF00069.20 EMC80899.1 - 1.6e-75 253.5 0.0 3.4e-75 252.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80899.1 - 4.7e-40 137.2 0.0 9.5e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EMC80899.1 - 2.8e-15 55.4 0.1 6.1e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EMC80899.1 - 1.7e-07 30.4 0.0 4.3e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC80899.1 - 1.6e-05 24.1 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC80899.1 - 0.00014 21.7 0.0 0.017 14.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC80899.1 - 0.01 15.3 0.0 0.032 13.8 0.0 1.9 1 0 0 1 1 1 0 Choline/ethanolamine kinase TLE_N PF03920.10 EMC80900.1 - 3.6e-68 227.5 7.9 6.1e-68 226.8 5.5 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 EMC80900.1 - 2.7e-25 87.2 22.7 7.1e-09 35.2 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat HALZ PF02183.13 EMC80900.1 - 0.0046 16.6 0.8 0.0092 15.6 0.5 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper G-alpha PF00503.15 EMC80901.1 - 3.5e-117 391.3 2.0 3.9e-117 391.2 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC80901.1 - 3.8e-12 45.7 0.2 2.2e-11 43.3 0.2 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMC80901.1 - 0.11 13.0 0.1 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Trypsin PF00089.21 EMC80902.1 - 6.1e-38 130.6 0.2 6.8e-38 130.4 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC80902.1 - 0.02 14.1 0.1 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) 7tm_1 PF00001.16 EMC80903.1 - 5.1e-38 130.6 18.9 5.1e-38 130.6 13.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC80903.1 - 1.7e-06 27.4 7.3 1.7e-06 27.4 5.1 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 EMC80903.1 - 0.0002 20.5 15.5 0.0003 20.0 10.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC80903.1 - 0.0058 15.7 13.7 0.011 14.8 9.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TctB PF07331.6 EMC80903.1 - 0.042 13.5 18.9 0.43 10.2 0.9 3.4 1 1 2 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF3671 PF12420.3 EMC80903.1 - 5.7 6.9 11.5 0.2 11.6 1.9 2.8 3 1 0 3 3 3 0 Protein of unknown function Peptidase_M28 PF04389.12 EMC80904.1 - 5e-12 45.9 0.0 8.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 EMC80904.1 - 4.9e-06 25.9 0.0 8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Nicastrin RRM_1 PF00076.17 EMC80905.1 - 1.1e-37 127.4 0.0 3.7e-17 61.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC80905.1 - 1.4e-25 89.0 0.2 1.8e-11 43.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC80905.1 - 2.6e-24 84.8 0.0 4.9e-10 39.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EMC80905.1 - 0.0036 17.2 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 1 RNA binding domain Nup35_RRM_2 PF14605.1 EMC80905.1 - 0.066 13.0 0.0 1.4 8.7 0.0 2.9 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif adh_short PF00106.20 EMC80906.1 - 1.4e-27 96.6 0.1 1.7e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC80906.1 - 3.3e-15 56.5 0.0 4.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC80906.1 - 1.6e-08 34.4 0.1 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMC80906.1 - 0.0013 17.9 0.1 0.0015 17.7 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Med25_SD1 PF11235.3 EMC80907.1 - 0.076 13.3 0.1 0.089 13.1 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 RRM_1 PF00076.17 EMC80908.1 - 1.5e-13 50.1 0.0 3.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC80908.1 - 1.5e-13 50.4 0.0 3.7e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC80908.1 - 5.1e-11 42.2 0.0 9.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.22 EMC80908.1 - 2.7e-10 39.4 0.9 7.5e-10 38.0 0.6 1.8 1 0 0 1 1 1 1 SAP domain RRM_1 PF00076.17 EMC80909.1 - 1.2e-14 53.6 0.0 2.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC80909.1 - 1.2e-14 54.0 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC80909.1 - 1.7e-10 40.5 0.0 3.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 EMC80910.1 - 1.9e-32 111.4 5.1 8.5e-19 67.6 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC80910.1 - 3e-21 74.0 1.2 6e-07 28.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMC80910.1 - 9.5e-20 70.1 3.2 4.4e-10 39.4 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC80910.1 - 3.3e-17 62.4 0.5 5e-12 46.0 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC80910.1 - 1.1e-13 49.9 0.9 0.0032 17.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat DUF724 PF05266.9 EMC80910.1 - 0.013 15.0 12.7 0.024 14.2 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ATG16 PF08614.6 EMC80910.1 - 0.039 13.7 19.2 0.039 13.7 9.9 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Nnf1 PF03980.9 EMC80910.1 - 0.086 12.8 8.3 0.18 11.7 0.1 3.1 3 1 0 3 3 3 0 Nnf1 DUF4618 PF15397.1 EMC80910.1 - 0.12 11.7 10.1 1.3 8.3 3.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) HOOK PF05622.7 EMC80910.1 - 0.19 9.4 15.3 0.31 8.7 10.6 1.2 1 0 0 1 1 1 0 HOOK protein ERM PF00769.14 EMC80910.1 - 0.2 11.1 18.1 0.41 10.1 12.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Snapin_Pallidin PF14712.1 EMC80910.1 - 0.25 11.6 6.3 0.54 10.5 1.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Filament PF00038.16 EMC80910.1 - 0.27 10.6 15.6 1.3 8.4 10.7 2.0 1 1 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.1 EMC80910.1 - 0.35 9.2 6.0 0.5 8.7 4.2 1.2 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EMC80910.1 - 0.56 9.2 17.9 0.032 13.2 8.7 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 FUSC PF04632.7 EMC80910.1 - 0.57 8.5 3.9 0.87 7.9 2.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.4 EMC80910.1 - 0.85 9.4 21.8 5.1 6.9 14.9 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EMC80910.1 - 0.96 9.8 13.6 0.36 11.1 2.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 EMC80910.1 - 1.2 8.2 14.4 3.8 6.6 10.0 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EMC80910.1 - 1.3 8.8 4.2 0.78 9.5 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EMC80910.1 - 1.4 6.6 7.5 2 6.1 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMC80910.1 - 1.6 8.2 25.6 22 4.5 17.8 2.3 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 EMC80910.1 - 2.8 6.4 15.5 0.27 9.8 5.7 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.7 EMC80910.1 - 4.4 7.7 15.3 0.31 11.4 1.6 3.5 2 1 1 3 3 3 0 SlyX CENP-Q PF13094.1 EMC80910.1 - 4.9 7.1 19.7 19 5.2 13.7 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Macoilin PF09726.4 EMC80910.1 - 5.1 5.2 12.0 6.9 4.8 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Laminin_II PF06009.7 EMC80910.1 - 6.2 6.5 10.3 5.9 6.6 3.8 2.8 2 1 1 3 3 3 0 Laminin Domain II DUF607 PF04678.8 EMC80910.1 - 7.3 6.4 7.2 22 4.9 2.0 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF607 SIR2 PF02146.12 EMC80911.1 - 3.3e-25 88.8 0.0 1.8e-17 63.6 0.0 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 EMC80911.1 - 0.0013 18.5 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_1 PF00170.16 EMC80912.1 - 1.9e-12 46.9 16.8 2.7e-12 46.4 10.5 2.0 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EMC80912.1 - 1.9e-10 40.4 16.8 3.2e-10 39.6 7.4 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 EMC80912.1 - 3.2e-05 24.1 11.8 3.2e-05 24.1 8.2 1.5 1 1 0 1 1 1 1 bZIP Maf transcription factor ADIP PF11559.3 EMC80912.1 - 0.0023 17.8 11.5 0.0036 17.2 8.0 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EMC80912.1 - 0.025 14.3 2.0 0.032 14.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RNA_polI_A14 PF08203.6 EMC80912.1 - 0.055 13.7 2.1 0.089 13.0 1.5 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Atg14 PF10186.4 EMC80912.1 - 0.097 11.6 10.5 0.1 11.5 7.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EMC80912.1 - 0.1 11.6 8.7 0.13 11.2 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMC80912.1 - 0.13 10.1 6.1 0.13 10.0 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC37_N PF03234.9 EMC80912.1 - 0.27 11.5 4.6 0.4 11.0 3.2 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding IncA PF04156.9 EMC80912.1 - 0.77 9.3 12.9 0.36 10.4 7.4 1.5 1 1 1 2 2 2 0 IncA protein OS-D PF03392.8 EMC80912.1 - 0.93 9.5 4.8 0.47 10.4 1.9 1.5 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D BRE1 PF08647.6 EMC80912.1 - 0.97 9.4 11.7 0.51 10.3 6.5 1.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.9 EMC80912.1 - 1.2 8.7 8.0 1.5 8.4 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3552 PF12072.3 EMC80912.1 - 1.5 7.9 13.3 2.4 7.3 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DIRP PF06584.8 EMC80912.1 - 2 8.3 5.6 1.9 8.4 1.9 2.1 1 1 2 3 3 3 0 DIRP Uds1 PF15456.1 EMC80912.1 - 2.6 8.0 11.3 3.2 7.7 7.8 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Herpes_BLRF2 PF05812.7 EMC80912.1 - 3.2 7.5 14.1 0.41 10.4 2.1 2.5 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 EMC80912.1 - 7.5 6.9 12.1 0.79 10.0 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Pkinase PF00069.20 EMC80913.1 - 3e-60 203.5 0.0 3.7e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80913.1 - 3.1e-34 118.2 0.0 3.2e-33 114.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC80913.1 - 0.00052 19.0 0.0 0.001 18.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EMC80913.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMC80913.1 - 0.024 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BTB PF00651.26 EMC80914.1 - 1.2e-33 115.3 0.1 2e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC80914.1 - 1.7e-25 87.9 19.5 3.9e-08 33.1 0.4 4.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC80914.1 - 4.4e-16 58.1 24.0 2e-05 24.6 1.0 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC80914.1 - 4.5e-14 51.6 19.6 0.00053 20.1 0.6 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC80914.1 - 0.00049 20.1 13.7 0.25 11.5 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC80914.1 - 0.01 15.6 14.3 0.011 15.5 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EMC80914.1 - 0.095 12.9 0.5 0.095 12.9 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type GAGA PF09237.6 EMC80914.1 - 0.14 11.7 8.0 0.27 10.8 0.1 3.7 1 1 3 4 4 4 0 GAGA factor DUF2321 PF10083.4 EMC80914.1 - 0.19 11.1 4.5 1.2 8.6 0.4 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) PRP21_like_P PF12230.3 EMC80914.1 - 0.37 10.2 6.8 0.17 11.3 0.1 2.6 2 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_2 PF12756.2 EMC80914.1 - 1 9.5 14.8 2.4 8.2 1.0 4.3 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Baculo_IE-1 PF05290.6 EMC80914.1 - 2 8.1 7.9 10 5.8 1.1 2.9 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) Zn_Tnp_IS1595 PF12760.2 EMC80914.1 - 4 7.3 14.6 1.2 8.9 1.5 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-C2H2_7 PF15269.1 EMC80914.1 - 7.3 6.5 11.1 4.6 7.1 0.2 3.3 2 1 1 3 3 3 0 Zinc-finger Nrf1_activ_bdg PF10492.4 EMC80915.1 - 7.3e-05 23.1 35.4 20 5.6 0.1 9.8 1 1 7 8 8 8 7 Nrf1 activator activation site binding domain Cornifin PF02389.10 EMC80915.1 - 0.0053 16.5 50.8 57 3.3 35.2 3.3 1 1 0 1 1 1 1 Cornifin (SPRR) family GTP_EFTU PF00009.22 EMC80916.1 - 7.9e-61 204.7 0.0 1.1e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMC80916.1 - 1.4e-39 134.3 0.1 3.8e-39 132.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EMC80916.1 - 1.6e-22 79.1 0.0 3.9e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EMC80916.1 - 2.3e-13 49.7 0.0 5.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EMC80916.1 - 1.5e-12 47.4 0.3 1e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC80916.1 - 1.5e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.20 EMC80917.1 - 6.6e-73 245.0 0.4 1.5e-72 243.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80917.1 - 9.8e-37 126.4 0.0 2.6e-36 125.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EMC80917.1 - 5.6e-06 25.5 0.5 3.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_trans_3N PF02885.12 EMC80917.1 - 0.051 13.1 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Bap31 PF05529.7 EMC80917.1 - 0.079 12.4 7.4 0.17 11.2 5.1 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Adeno_PIX PF03955.9 EMC80917.1 - 0.11 13.0 1.4 0.26 11.8 0.1 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Fib_alpha PF08702.5 EMC80917.1 - 0.14 12.3 10.8 0.11 12.5 3.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.4 EMC80917.1 - 0.15 12.0 11.5 0.37 10.7 8.0 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein OmpH PF03938.9 EMC80917.1 - 0.17 11.8 12.8 0.34 10.8 8.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APH PF01636.18 EMC80917.1 - 0.18 11.4 0.4 0.76 9.4 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family TPR_MLP1_2 PF07926.7 EMC80917.1 - 0.25 11.1 19.2 0.63 9.7 13.3 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cache_2 PF08269.6 EMC80917.1 - 0.29 11.1 2.8 20 5.2 0.0 3.0 2 0 0 2 2 2 0 Cache domain BLOC1_2 PF10046.4 EMC80917.1 - 0.38 10.9 9.5 1.4 9.1 2.6 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 EMC80917.1 - 0.61 10.1 12.0 2 8.4 8.3 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.6 EMC80917.1 - 1.1 6.7 5.5 2 5.8 3.8 1.4 1 0 0 1 1 1 0 Prominin YrbL-PhoP_reg PF10707.4 EMC80917.1 - 1.2 8.4 7.6 0.48 9.7 0.0 3.2 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF3323 PF11796.3 EMC80917.1 - 1.2 8.3 7.4 17 4.6 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) TMPIT PF07851.8 EMC80917.1 - 2.4 7.1 8.9 4 6.4 6.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 EMC80917.1 - 7.7 6.0 20.7 12 5.3 13.8 1.7 1 1 0 1 1 1 0 IncA protein AAA_18 PF13238.1 EMC80918.1 - 2.3e-11 44.0 0.0 4.3e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC80918.1 - 1.9e-05 25.4 0.0 3.9e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EMC80918.1 - 0.0024 17.4 0.2 0.022 14.3 0.2 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EMC80918.1 - 0.0048 16.8 0.0 0.021 14.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EMC80918.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMC80918.1 - 0.045 13.4 0.1 0.47 10.1 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EMC80918.1 - 0.12 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein BNIP2 PF12496.3 EMC80919.1 - 1.3e-40 138.4 0.2 1.8e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 EMC80919.1 - 1.8e-30 105.8 0.1 2.5e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EMC80919.1 - 6.7e-08 32.1 0.2 9.8e-08 31.6 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Glyco_transf_10 PF00852.14 EMC80920.1 - 1.8e-127 424.7 3.4 2.1e-127 424.4 2.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Glyco_trans_1_2 PF13524.1 EMC80920.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 EspB PF05802.6 EMC80922.1 - 0.023 13.6 5.1 0.025 13.5 3.5 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF883 PF05957.8 EMC80922.1 - 0.027 14.8 4.0 0.077 13.4 2.8 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AAA_32 PF13654.1 EMC80922.1 - 0.086 11.4 0.1 0.092 11.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain Flagellin_N PF00669.15 EMC80922.1 - 0.094 12.5 4.6 0.11 12.3 3.2 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Holin_LLH PF09682.5 EMC80922.1 - 0.1 12.6 3.1 0.12 12.5 2.2 1.2 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) FIVAR PF07554.8 EMC80922.1 - 0.12 12.6 10.4 0.78 10.0 4.9 2.1 1 1 1 2 2 2 0 Uncharacterised Sugar-binding Domain CBFD_NFYB_HMF PF00808.18 EMC80922.1 - 0.13 12.3 1.1 0.34 11.0 0.3 1.8 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3774 PF12609.3 EMC80922.1 - 0.19 12.6 2.6 0.22 12.3 1.8 1.1 1 0 0 1 1 1 0 Wound-induced protein Tape_meas_lam_C PF09718.5 EMC80922.1 - 0.24 11.3 7.2 3.4 7.6 5.2 2.0 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ATP-synt_B PF00430.13 EMC80922.1 - 0.33 10.7 6.5 0.42 10.4 4.5 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) YtxH PF12732.2 EMC80922.1 - 0.78 10.1 4.5 1.5 9.2 3.1 1.6 1 1 0 1 1 1 0 YtxH-like protein HK97-gp10_like PF04883.7 EMC80922.1 - 1.1 10.2 4.8 28 5.7 3.3 2.0 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component FliE PF02049.13 EMC80922.1 - 1.3 9.1 5.9 1.5 8.9 4.1 1.1 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE YbaB_DNA_bd PF02575.11 EMC80922.1 - 1.6 8.6 7.6 2.2 8.2 1.6 2.2 1 1 1 2 2 2 0 YbaB/EbfC DNA-binding family MT0933_antitox PF14013.1 EMC80922.1 - 3.2 7.9 12.6 38 4.4 8.7 2.4 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF2564 PF10819.3 EMC80922.1 - 3.5 7.7 9.3 11 6.2 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) Synuclein PF01387.12 EMC80923.1 - 1.6e-52 176.8 24.6 1.7e-52 176.7 17.1 1.0 1 0 0 1 1 1 1 Synuclein Apolipoprotein PF01442.13 EMC80923.1 - 0.03 13.8 0.3 0.035 13.6 0.2 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MoaF PF10703.4 EMC80923.1 - 0.054 12.5 1.2 0.055 12.5 0.8 1.1 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F DSRB PF10781.4 EMC80923.1 - 0.086 12.3 0.4 0.51 9.8 0.1 2.3 1 1 1 2 2 2 0 Dextransucrase DSRB Mononeg_mRNAcap PF14318.1 EMC80923.1 - 0.12 11.4 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V EndoU_bacteria PF14436.1 EMC80923.1 - 0.15 11.8 1.3 0.19 11.5 0.9 1.1 1 0 0 1 1 1 0 Bacterial EndoU nuclease YtxH PF12732.2 EMC80923.1 - 3.8 7.9 6.6 19 5.6 4.6 2.0 1 1 0 1 1 1 0 YtxH-like protein C1q PF00386.16 EMC80924.1 - 1.7e-17 63.6 0.2 5.8e-17 61.8 0.2 2.0 1 0 0 1 1 1 1 C1q domain MbeD_MobD PF04899.7 EMC80924.1 - 1.1 9.2 12.6 0.34 10.8 0.4 4.1 5 0 0 5 5 5 0 MbeD/MobD like Pkinase PF00069.20 EMC80925.1 - 7.9e-56 189.0 0.0 1.2e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80925.1 - 2.2e-38 131.7 0.0 3.1e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 EMC80925.1 - 2.3e-15 55.5 0.5 4.9e-15 54.5 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 EMC80925.1 - 3.1e-13 50.1 10.8 3.1e-13 50.1 7.5 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 EMC80925.1 - 0.2 11.3 0.0 0.61 9.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family TIR PF01582.15 EMC80926.1 - 2.5e-26 91.8 0.0 4.5e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.1 EMC80926.1 - 5.1e-07 30.0 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC80926.1 - 2.2e-06 27.4 0.0 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC80926.1 - 3.1e-05 24.0 0.0 8.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain TIR_2 PF13676.1 EMC80926.1 - 9.7e-05 22.4 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 EMC80926.1 - 0.00016 21.7 0.0 0.00042 20.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC80926.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.1 2 1 0 2 2 2 0 Immunoglobulin V-set domain I-set PF07679.11 EMC80928.1 - 0.00016 21.4 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 EMC80928.1 - 0.00048 20.0 0.1 0.00052 19.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC80928.1 - 0.0018 18.3 0.1 0.0019 18.3 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 EMC80928.1 - 0.012 15.3 0.2 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Ig_3 PF13927.1 EMC80928.1 - 0.013 16.0 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Sp38 PF07354.7 EMC80928.1 - 0.079 11.5 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) I-set PF07679.11 EMC80929.1 - 0.01 15.6 0.0 0.05 13.4 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC80929.1 - 0.051 13.6 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC80929.1 - 0.073 12.9 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain Glycos_transf_2 PF00535.21 EMC80930.1 - 1.4e-26 93.2 0.0 2.3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC80930.1 - 1.1e-17 64.1 0.1 1.8e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC80930.1 - 7.2e-07 29.2 0.0 0.00038 20.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMC80930.1 - 5.5e-05 22.3 0.0 8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC80930.1 - 0.00078 18.8 0.0 0.0023 17.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 EMC80930.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like GTF2I PF02946.9 EMC80931.1 - 2.4e-181 588.0 17.6 1.5e-31 108.0 0.0 6.2 6 0 0 6 6 6 6 GTF2I-like repeat Herpes_IE68 PF02479.11 EMC80931.1 - 0.0022 17.1 0.4 3.5 6.8 0.0 4.4 5 0 0 5 5 5 2 Herpesvirus immediate early protein SH3_1 PF00018.23 EMC80932.1 - 6e-31 105.5 0.6 1.1e-14 53.5 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EMC80932.1 - 4.4e-25 86.9 0.3 1.8e-11 43.4 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EMC80932.1 - 1.3e-22 79.0 0.0 7.9e-12 44.4 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EMC80932.1 - 9.2e-13 47.9 0.3 1.6e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 PX domain SH3_3 PF08239.6 EMC80932.1 - 0.0013 18.8 1.0 0.67 10.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain DUF239 PF03080.10 EMC80932.1 - 0.0061 15.6 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF239) Cylicin_N PF15241.1 EMC80933.1 - 0.1 12.4 1.9 0.13 12.0 1.3 1.1 1 0 0 1 1 1 0 Cylicin N-terminus G-patch PF01585.18 EMC80934.1 - 1.8e-17 62.8 0.8 3.4e-17 61.9 0.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC80934.1 - 1e-08 34.8 0.1 1e-08 34.8 0.1 2.6 3 0 0 3 3 3 1 DExH-box splicing factor binding site IQ PF00612.22 EMC80935.1 - 6.8e-13 47.0 22.4 3.8e-05 22.9 0.8 4.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif Radical_SAM_N PF08497.5 EMC80935.1 - 0.062 12.2 1.7 0.087 11.7 1.2 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal Pfg27 PF09216.5 EMC80935.1 - 1.2 8.7 10.4 0.7 9.4 5.8 1.6 2 0 0 2 2 2 0 Pfg27 Rrp15p PF07890.7 EMC80937.1 - 2.2e-40 137.7 14.8 3.8e-40 136.9 10.3 1.4 1 0 0 1 1 1 1 Rrp15p TGFb_propeptide PF00688.13 EMC80938.1 - 1.1e-36 126.3 0.1 1.7e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC80938.1 - 5.9e-31 106.8 2.1 1.6e-30 105.4 1.4 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain Abhydrolase_2 PF02230.11 EMC80939.1 - 9.2e-38 129.8 0.0 1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMC80939.1 - 7.6e-11 41.9 0.0 8.2e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMC80939.1 - 2.7e-07 30.3 0.1 0.00031 20.3 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC80939.1 - 6.4e-06 25.5 1.5 0.00089 18.5 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMC80939.1 - 3e-05 24.0 0.0 7.1e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMC80939.1 - 6.6e-05 22.3 0.0 8.3e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 EMC80939.1 - 0.0029 17.0 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 EMC80939.1 - 0.0029 17.2 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EMC80939.1 - 0.0037 16.8 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EMC80939.1 - 0.13 11.6 0.2 0.31 10.4 0.1 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Cation_efflux PF01545.16 EMC80940.1 - 3.2e-68 229.8 0.1 3.7e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Cation efflux family DUF2721 PF11026.3 EMC80940.1 - 3.2 7.3 7.2 23 4.5 3.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF1673 PF07895.6 EMC80940.1 - 6.2 6.2 10.9 0.09 12.2 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) Inositol_P PF00459.20 EMC80941.1 - 2.4e-57 194.2 0.4 3.3e-57 193.8 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family tRNA-synt_1 PF00133.17 EMC80942.1 - 2.5e-168 560.8 0.2 3.4e-168 560.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMC80942.1 - 1e-28 100.1 3.0 8.7e-19 67.4 0.0 3.6 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMC80942.1 - 2e-27 95.8 0.0 4.9e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 EMC80942.1 - 0.00012 21.4 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EMC80942.1 - 0.00026 20.2 0.0 0.064 12.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 EMC80942.1 - 0.001 18.6 3.3 0.001 18.6 2.3 2.9 3 0 0 3 3 3 1 Zinc finger found in FPG and IleRS RAB3GAP2_C PF14656.1 EMC80943.1 - 1.7e-233 776.1 18.1 2.3e-233 775.6 12.5 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.1 EMC80943.1 - 1e-156 522.1 0.0 1.5e-156 521.5 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SRP54_N PF02881.14 EMC80943.1 - 0.035 14.2 0.4 0.84 9.7 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain Pkinase PF00069.20 EMC80944.1 - 2.1e-77 259.7 0.0 3.1e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC80944.1 - 4.9e-44 150.3 0.0 7.3e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EMC80944.1 - 8.2e-19 66.7 0.1 1.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EMC80944.1 - 3e-07 29.7 0.0 6e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EMC80944.1 - 0.00016 21.1 0.3 0.00031 20.1 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA PF00627.26 EMC80944.1 - 0.00023 20.8 0.0 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.9 EMC80944.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.6 EMC80944.1 - 0.062 13.5 0.1 0.2 11.8 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) APH PF01636.18 EMC80944.1 - 0.15 11.7 0.1 0.53 9.9 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Profilin PF00235.14 EMC80945.1 - 1.5e-22 79.9 0.0 1.6e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Profilin MOSC PF03473.12 EMC80946.1 - 5.4e-29 100.3 0.0 8.5e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EMC80946.1 - 1.4e-21 76.3 0.0 4.1e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Homeobox PF00046.24 EMC80947.1 - 4.4e-20 71.0 0.5 4.7e-20 70.9 0.4 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC80947.1 - 0.0066 16.1 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC80947.1 - 0.021 13.8 0.1 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MIP-T3 PF10243.4 EMC80948.1 - 3.6e-07 29.0 42.1 3.6e-07 29.0 29.2 4.1 2 1 2 4 4 4 1 Microtubule-binding protein MIP-T3 Patatin PF01734.17 EMC80949.1 - 6.6e-21 75.1 1.3 3.1e-19 69.7 0.9 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.24 EMC80949.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain IQ PF00612.22 EMC80950.1 - 0.072 12.7 0.1 0.072 12.7 0.1 3.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif Phostensin PF13914.1 EMC80951.1 - 1.3e-39 135.3 9.1 3.1e-39 134.1 0.4 2.7 3 0 0 3 3 3 2 Phostensin PP1-binding and SH3-binding region Torsin PF06309.6 EMC80952.1 - 2.5e-14 53.2 0.1 7.4e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 Torsin AAA_22 PF13401.1 EMC80952.1 - 0.0048 17.0 0.1 0.47 10.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC80952.1 - 0.0065 16.7 0.0 0.023 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMC80952.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EMC80952.1 - 0.075 12.0 0.0 0.13 11.2 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.1 EMC80952.1 - 0.081 13.7 0.0 0.24 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMC80952.1 - 0.087 12.2 0.0 0.19 11.1 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EMC80952.1 - 0.14 12.1 0.0 0.61 10.0 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain Pkinase_Tyr PF07714.12 EMC80953.1 - 1.3e-84 283.3 0.0 1.7e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC80953.1 - 1.2e-44 152.4 0.0 2e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.20 EMC80953.1 - 1e-21 77.0 0.0 4.6e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain TMEM154 PF15102.1 EMC80953.1 - 0.0019 17.9 0.5 0.0034 17.0 0.4 1.3 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 EMC80953.1 - 0.02 14.5 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Kinase-like PF14531.1 EMC80953.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EssA PF10661.4 EMC80953.1 - 0.17 11.5 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF2475 PF10629.4 EMC80954.1 - 6.1e-16 58.4 0.5 6.4e-16 58.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) DUF2475 PF10629.4 EMC80955.1 - 2.1e-07 31.0 1.4 0.002 18.3 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2475) GDA1_CD39 PF01150.12 EMC80956.1 - 2.2e-36 125.2 0.0 2.7e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family COX7a PF02238.10 EMC80957.1 - 1e-26 92.3 0.0 1.3e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa BAH PF01426.13 EMC80958.1 - 8.4e-29 99.7 0.4 3.4e-28 97.7 0.3 2.0 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.19 EMC80958.1 - 2e-12 47.5 2.2 3.8e-12 46.6 0.0 2.6 2 1 0 2 2 2 1 ELM2 domain GATA PF00320.22 EMC80958.1 - 1.8e-08 33.5 9.0 3.5e-08 32.6 6.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.26 EMC80958.1 - 0.00013 21.9 0.0 0.00038 20.4 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Herpes_US12 PF05363.7 EMC80958.1 - 0.033 14.6 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 Herpesvirus US12 family 3-HAO PF06052.7 EMC80959.1 - 3.2e-77 257.0 0.0 1.9e-73 244.8 0.1 2.0 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EMC80959.1 - 1.2e-11 43.9 0.0 4.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EMC80959.1 - 0.0051 16.4 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 EMC80959.1 - 0.0053 16.1 0.0 0.82 9.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EMC80959.1 - 0.021 14.2 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Cupin DUF2428 PF10350.4 EMC80961.1 - 5.7e-77 258.1 0.4 1.9e-76 256.4 0.3 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) PH PF00169.24 EMC80962.1 - 1.7e-23 82.8 1.3 4.5e-17 62.1 0.0 3.3 3 0 0 3 3 3 2 PH domain MyTH4 PF00784.12 EMC80962.1 - 5.8e-20 71.3 0.4 2.7e-19 69.1 0.3 2.3 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.13 EMC80962.1 - 4.9e-12 46.1 0.0 4.9e-12 46.1 0.0 2.8 2 1 0 2 2 2 1 FERM central domain PH_11 PF15413.1 EMC80962.1 - 3e-08 33.8 1.4 3e-08 33.8 1.0 5.3 4 2 0 4 4 4 1 Pleckstrin homology domain DLIC PF05783.6 EMC80963.1 - 6.4e-10 38.3 0.0 1.8e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.7 EMC80963.1 - 9.2e-05 21.6 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC80963.1 - 0.0026 18.2 0.0 0.017 15.6 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein DnaJ PF00226.26 EMC80964.1 - 4.8e-18 64.6 1.4 1.3e-17 63.2 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.26 EMC80964.1 - 4.2e-12 45.9 1.0 9.8e-08 31.9 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC80964.1 - 1.3e-07 31.5 0.1 0.02 14.9 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4234 PF14018.1 EMC80964.1 - 0.059 13.1 0.2 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) zf-HC5HC2H_2 PF13832.1 EMC80965.1 - 3.9e-31 107.2 20.5 4.7e-31 107.0 7.9 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC80965.1 - 1.4e-20 73.2 10.5 1.4e-20 73.2 7.3 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EMC80965.1 - 6.4e-13 47.7 4.4 6.4e-13 47.7 3.0 2.8 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 EMC80965.1 - 4.7e-07 29.3 9.9 4.7e-07 29.3 6.9 2.9 2 0 0 2 2 2 2 PHD-finger LIM PF00412.17 EMC80966.1 - 8.6e-09 35.3 7.1 1.1e-08 35.0 4.9 1.1 1 0 0 1 1 1 1 LIM domain Nebulin PF00880.13 EMC80966.1 - 0.0053 16.3 1.3 0.0083 15.6 0.1 1.9 2 0 0 2 2 2 1 Nebulin repeat Nebulin PF00880.13 EMC80967.1 - 1.3e-143 460.5 90.4 6.3e-10 38.1 0.0 22.3 22 0 0 22 22 22 22 Nebulin repeat SH3_9 PF14604.1 EMC80967.1 - 1.4e-15 56.5 0.0 2.6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC80967.1 - 8.5e-13 47.4 0.5 1.7e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMC80967.1 - 3e-05 23.4 0.0 6.8e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PSI PF01437.20 EMC80968.1 - 9.7e-08 32.0 11.5 1.7e-07 31.2 7.9 1.4 1 0 0 1 1 1 1 Plexin repeat EGF PF00008.22 EMC80969.1 - 0.0023 17.8 5.8 0.0037 17.2 4.0 1.4 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.8 EMC80969.1 - 0.075 13.2 8.3 0.13 12.4 5.7 1.4 1 0 0 1 1 1 0 EGF-like domain MAM PF00629.18 EMC80970.1 - 6.1e-23 81.3 1.5 7e-23 81.1 1.1 1.0 1 0 0 1 1 1 1 MAM domain MAM PF00629.18 EMC80971.1 - 6.5e-45 152.7 0.0 7.2e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 MAM domain zf-TRM13_CCCH PF11722.3 EMC80971.1 - 0.092 12.1 0.8 0.17 11.2 0.5 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein Ski_Sno PF02437.12 EMC80971.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 SKI/SNO/DAC family MAM PF00629.18 EMC80972.1 - 2.3e-70 235.5 0.2 5.4e-38 130.2 0.1 2.0 2 0 0 2 2 2 2 MAM domain Ldl_recept_a PF00057.13 EMC80972.1 - 1.5e-10 40.7 9.4 4.7e-10 39.2 6.5 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A MAM PF00629.18 EMC80973.1 - 3.6e-25 88.5 0.7 4.1e-25 88.4 0.5 1.0 1 0 0 1 1 1 1 MAM domain Arf PF00025.16 EMC80974.1 - 2.8e-65 218.8 0.1 3.1e-65 218.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC80974.1 - 2.5e-14 53.0 0.0 2.6e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC80974.1 - 3.8e-13 49.0 0.1 4.5e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC80974.1 - 1.4e-11 44.9 0.1 1.8e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EMC80974.1 - 8.8e-09 34.5 0.5 2.8e-06 26.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMC80974.1 - 5.1e-08 32.3 0.2 5.8e-08 32.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC80974.1 - 7.4e-08 32.3 0.1 1e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC80974.1 - 0.00035 20.0 0.1 0.0066 15.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EMC80974.1 - 0.0028 17.5 0.2 0.01 15.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EMC80974.1 - 0.1 11.9 0.7 0.44 9.8 0.2 1.9 1 1 1 2 2 2 0 Ferrous iron transport protein B KaiC PF06745.8 EMC80974.1 - 0.1 11.7 0.2 0.25 10.4 0.1 1.7 1 1 0 1 1 1 0 KaiC Nol1_Nop2_Fmu PF01189.12 EMC80975.1 - 3.5e-38 131.5 0.0 1.1e-37 129.9 0.0 1.7 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EMC80975.1 - 2.2e-09 37.0 0.0 5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC80975.1 - 1.6e-08 34.7 0.0 3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EMC80975.1 - 4.1e-08 33.2 0.0 7.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC80975.1 - 8.2e-08 32.8 0.0 1.7e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.15 EMC80975.1 - 0.00023 20.8 0.1 0.00048 19.7 0.1 1.6 1 0 0 1 1 1 1 PUA domain Methyltransf_15 PF09445.5 EMC80975.1 - 0.00093 18.7 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 EMC80975.1 - 0.0033 17.7 0.0 0.0092 16.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 EMC80975.1 - 0.0033 16.9 0.0 0.0073 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EMC80975.1 - 0.0036 17.7 0.1 0.031 14.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC80975.1 - 0.0038 16.6 0.0 0.044 13.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMC80975.1 - 0.0097 15.0 0.0 0.041 13.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.10 EMC80975.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 EMC80975.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.4 EMC80975.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Guanylate_kin PF00625.16 EMC80976.1 - 1.4e-49 167.9 1.1 2.1e-49 167.4 0.1 1.8 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.3 EMC80976.1 - 6.1e-24 83.6 7.8 6.1e-24 83.6 5.4 2.7 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.23 EMC80976.1 - 9.7e-05 21.6 0.1 0.00034 19.9 0.1 2.0 2 0 0 2 2 2 1 SH3 domain ImpA-rel_N PF06812.7 EMC80976.1 - 0.043 13.5 0.1 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 ImpA-related N-terminal SH3_9 PF14604.1 EMC80976.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Zip PF02535.17 EMC80977.1 - 2.4e-65 220.6 11.6 3.7e-65 220.0 8.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4366 PF14283.1 EMC80978.1 - 0.0055 16.1 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Lectin_C PF00059.16 EMC80978.1 - 0.0088 16.6 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain 7tm_3 PF00003.17 EMC80979.1 - 1.4e-85 286.4 15.8 1.8e-85 286.0 10.9 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 EMC80979.1 - 2e-43 148.5 0.0 2.6e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.9 EMC80979.1 - 2.4e-14 52.7 10.9 4.7e-14 51.8 7.6 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR POT1 PF02765.12 EMC80980.1 - 1.3e-30 106.2 0.2 1.5e-29 102.8 0.0 2.6 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EMC80980.1 - 0.00069 19.4 0.2 9.5 6.1 0.0 4.4 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain SAF_2 PF13144.1 EMC80980.1 - 0.087 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 SAF-like Keratin PF02422.11 EMC80981.1 - 9.6e-41 137.7 16.7 1e-40 137.5 11.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80983.1 - 2.6e-41 139.5 11.8 3.1e-41 139.2 8.2 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80984.1 - 1.5e-41 140.3 11.5 1.7e-41 140.1 8.0 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80985.1 - 7.5e-42 141.2 16.4 8.2e-42 141.1 11.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80986.1 - 1.1e-34 118.2 10.7 1.2e-34 118.1 7.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80987.1 - 3.8e-40 135.8 16.6 4.1e-40 135.6 11.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80989.1 - 6.7e-41 138.2 16.3 7.4e-41 138.0 11.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80990.1 - 9.5e-42 140.9 13.3 1.1e-41 140.7 9.2 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80991.1 - 3.2e-37 126.4 22.2 3.5e-37 126.2 15.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80992.1 - 3.4e-40 135.9 22.8 3.8e-40 135.8 15.8 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80994.1 - 1.8e-36 124.0 20.6 2e-36 123.8 14.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80995.1 - 2.5e-35 120.3 20.3 2.8e-35 120.2 14.1 1.0 1 0 0 1 1 1 1 Keratin Stanniocalcin PF03298.8 EMC80995.1 - 0.0019 17.2 2.7 0.0025 16.8 1.9 1.1 1 0 0 1 1 1 1 Stanniocalcin family Keratin PF02422.11 EMC80996.1 - 5.5e-45 151.3 19.6 6.2e-45 151.1 13.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80997.1 - 5.8e-45 151.2 19.4 6.6e-45 151.0 13.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80998.1 - 9.1e-41 137.7 15.8 1e-40 137.6 10.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC80999.1 - 3.1e-43 145.6 18.6 3.6e-43 145.4 12.9 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81000.1 - 2e-43 146.3 18.7 2.2e-43 146.1 13.0 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81001.1 - 2.2e-44 149.4 19.6 2.5e-44 149.2 13.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81002.1 - 9.8e-45 150.5 20.1 1.1e-44 150.3 14.0 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81003.1 - 8.1e-41 137.9 19.7 9e-41 137.8 13.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81004.1 - 3.1e-44 148.9 20.1 3.6e-44 148.7 13.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81005.1 - 1.7e-44 149.7 19.1 1.9e-44 149.5 13.2 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81006.1 - 1.5e-44 149.9 19.7 1.7e-44 149.7 13.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC81007.1 - 1e-40 137.6 9.0 1.1e-40 137.5 6.2 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC81007.1 - 0.069 13.1 2.9 0.1 12.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 EMC81008.1 - 2.2e-45 152.6 19.6 2.5e-45 152.4 13.6 1.0 1 0 0 1 1 1 1 Keratin Choline_kinase PF01633.15 EMC81009.1 - 1.4e-59 201.1 0.1 2e-59 200.6 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EMC81009.1 - 1e-13 51.6 0.0 2.2e-13 50.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMC81009.1 - 4e-05 22.9 0.3 8e-05 21.9 0.2 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Caps_assemb_Wzi PF14052.1 EMC81009.1 - 0.028 13.2 1.7 0.038 12.8 1.2 1.1 1 0 0 1 1 1 0 Capsule assembly protein Wzi Cast PF10174.4 EMC81010.1 - 8.3e-23 80.3 7.9 9.3e-23 80.2 5.5 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone SGT1 PF07093.6 EMC81010.1 - 0.069 11.5 0.7 0.069 11.5 0.5 1.0 1 0 0 1 1 1 0 SGT1 protein DUF2458 PF10454.4 EMC81010.1 - 0.084 12.7 1.7 0.099 12.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) SecD-TM1 PF13721.1 EMC81010.1 - 0.12 12.6 0.9 0.14 12.4 0.6 1.1 1 0 0 1 1 1 0 SecD export protein N-terminal TM region FlaC_arch PF05377.6 EMC81010.1 - 0.74 9.7 6.4 0.6 10.0 0.6 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.10 EMC81010.1 - 2.5 8.3 5.5 3.5 7.8 1.9 2.0 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF641 PF04859.7 EMC81010.1 - 4.5 7.0 6.2 7.9 6.2 0.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Glyco_hydro_47 PF01532.15 EMC81011.1 - 2.7e-118 395.5 0.0 3.1e-118 395.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Arf PF00025.16 EMC81013.1 - 1.3e-39 135.2 0.1 1.5e-39 134.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC81013.1 - 3e-16 59.2 0.0 3.4e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81013.1 - 8.2e-07 29.5 0.0 3.1e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EMC81013.1 - 1.1e-06 28.0 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC81013.1 - 1.3e-05 24.0 0.1 1.8e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 EMC81013.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC81013.1 - 0.0011 18.1 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HLH PF00010.21 EMC81014.1 - 3.8e-12 45.7 0.8 8.6e-12 44.5 0.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC81014.1 - 3e-08 33.2 0.3 7.2e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 Hairy Orange Oscp1 PF10188.4 EMC81014.1 - 0.015 15.1 0.4 0.023 14.4 0.3 1.2 1 0 0 1 1 1 0 Organic solute transport protein 1 FGE-sulfatase PF03781.11 EMC81015.1 - 6.6e-89 297.7 7.2 7.4e-89 297.5 5.0 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 SET PF00856.23 EMC81016.1 - 1.7e-25 90.2 0.0 4.7e-25 88.7 0.0 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EMC81016.1 - 1.5e-07 31.6 12.7 1.5e-07 31.6 8.8 2.1 2 0 0 2 2 2 1 Pre-SET motif LRR_8 PF13855.1 EMC81017.1 - 1.4e-49 165.6 66.1 3.3e-12 45.9 3.8 6.6 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 EMC81017.1 - 1.3e-30 104.4 44.8 3.9e-09 35.9 1.0 7.9 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC81017.1 - 5.1e-24 84.4 0.8 2.1e-11 43.6 2.0 3.7 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) I-set PF07679.11 EMC81017.1 - 9.7e-16 57.4 0.2 5.9e-15 54.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_1 PF00560.28 EMC81017.1 - 9.9e-12 43.1 37.6 0.027 14.4 0.1 12.3 13 0 0 13 13 13 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC81017.1 - 2.3e-11 41.9 19.9 1.7 9.2 0.0 11.3 12 0 0 12 12 11 4 Leucine rich repeat V-set PF07686.12 EMC81017.1 - 6.8e-09 35.6 0.0 2.1e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.1 EMC81017.1 - 9.9e-09 34.3 35.5 0.12 12.4 0.2 11.2 10 1 1 11 11 11 4 Leucine Rich repeat Ig_3 PF13927.1 EMC81017.1 - 4.7e-08 33.4 0.7 1.6e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 EMC81017.1 - 1.2e-07 31.7 0.0 3.8e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 EMC81017.1 - 1.9e-07 30.7 18.9 0.015 14.8 0.8 4.3 1 1 3 4 4 4 3 Leucine-rich repeat ig PF00047.20 EMC81017.1 - 6.7e-05 22.9 0.9 0.00097 19.2 0.1 3.3 3 1 0 3 3 3 1 Immunoglobulin domain LRRNT PF01462.13 EMC81017.1 - 0.00014 21.2 1.0 0.00014 21.2 0.7 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain fn3 PF00041.16 EMC81017.1 - 0.001 19.1 1.5 0.0023 18.0 1.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 EMC81017.1 - 0.0015 18.6 0.1 0.0045 17.1 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LON PF02190.11 EMC81018.1 - 4.5e-22 78.7 0.0 6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Yippee-Mis18 PF03226.9 EMC81018.1 - 0.097 12.7 5.5 0.12 12.4 2.5 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3786 PF12654.2 EMC81018.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Basic PF01586.11 EMC81019.1 - 2.5e-27 95.3 0.1 4.1e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Myogenic Basic domain HLH PF00010.21 EMC81019.1 - 1e-13 50.7 5.8 1.7e-13 50.0 4.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Basic PF01586.11 EMC81020.1 - 5.4e-28 97.5 3.0 5.4e-28 97.5 2.1 1.6 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.21 EMC81020.1 - 2.3e-15 56.0 4.5 3.3e-15 55.5 3.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myf5 PF12232.3 EMC81020.1 - 1e-06 29.2 2.6 1e-06 29.2 1.8 2.0 2 0 0 2 2 2 1 Myogenic determination factor 5 DUF1364 PF07102.7 EMC81020.1 - 0.019 14.8 1.9 0.03 14.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) DUF866 PF05907.8 EMC81020.1 - 0.15 11.5 0.9 0.18 11.2 0.6 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) PDZ PF00595.19 EMC81021.1 - 4e-21 74.9 0.4 7.2e-21 74.1 0.3 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 EMC81021.1 - 1.7e-17 62.8 0.1 3.4e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 L27 domain PDZ_2 PF13180.1 EMC81021.1 - 6.7e-05 22.7 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain ECH PF00378.15 EMC81021.1 - 0.44 9.6 5.3 1.4 7.9 1.4 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Viral_P18 PF04521.8 EMC81021.1 - 1 8.8 5.0 0.51 9.7 2.0 1.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ins_P5_2-kin PF06090.7 EMC81022.1 - 0.047 12.7 0.5 0.054 12.5 0.4 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase AraC_N PF06719.8 EMC81022.1 - 0.061 12.6 0.2 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus AKNA PF12443.3 EMC81022.1 - 0.091 12.7 1.8 0.12 12.4 1.2 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor PMC2NT PF08066.7 EMC81022.1 - 0.13 12.6 0.8 0.21 11.8 0.2 1.6 1 1 0 1 1 1 0 PMC2NT (NUC016) domain DUF3967 PF13152.1 EMC81022.1 - 0.4 10.3 2.8 0.28 10.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) tRNA-synt_2b PF00587.20 EMC81023.1 - 1.9e-71 239.1 0.0 3.4e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC81023.1 - 2.9e-23 81.6 0.2 1.6e-22 79.2 0.0 2.3 2 1 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.15 EMC81023.1 - 1.5e-10 40.5 3.9 5.4e-10 38.7 2.7 2.0 1 0 0 1 1 1 1 WHEP-TRS domain OS-D PF03392.8 EMC81023.1 - 0.0045 16.9 0.7 0.016 15.1 0.1 2.2 2 0 0 2 2 2 1 Insect pheromone-binding family, A10/OS-D zf-C2H2 PF00096.21 EMC81024.1 - 1.1e-69 226.6 112.5 1.1e-07 31.6 1.0 13.1 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC81024.1 - 1.8e-60 198.4 106.1 1.3e-09 37.8 0.7 15.0 14 1 0 14 14 14 14 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC81024.1 - 1e-37 125.6 100.0 0.00011 22.2 0.7 13.1 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC81024.1 - 9.7e-14 51.0 40.0 0.27 11.4 0.0 11.4 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC81024.1 - 1e-10 41.0 91.7 0.013 15.4 0.6 13.4 14 0 0 14 14 14 9 C2H2-type zinc finger zf-met PF12874.2 EMC81024.1 - 0.0002 21.4 55.6 1.3 9.3 0.1 10.8 10 0 0 10 10 10 5 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EMC81024.1 - 0.0025 17.7 76.0 0.062 13.2 4.1 11.9 7 3 4 11 11 11 2 Zinc ribbon domain LIM PF00412.17 EMC81024.1 - 0.0055 16.7 2.9 0.023 14.7 0.4 10.2 4 2 7 11 11 10 3 LIM domain C1_4 PF07975.7 EMC81024.1 - 0.026 14.5 3.6 0.026 14.5 2.5 8.2 2 2 7 9 9 9 0 TFIIH C1-like domain BolA PF01722.13 EMC81024.1 - 0.13 12.2 16.8 3.8 7.5 0.1 6.3 4 1 3 7 7 7 0 BolA-like protein GAGA PF09237.6 EMC81024.1 - 0.24 11.0 26.8 1.4 8.5 0.6 7.1 5 1 3 8 8 8 0 GAGA factor Chordopox_RPO7 PF05864.7 EMC81024.1 - 0.42 10.7 0.0 0.42 10.7 0.0 6.1 9 1 1 10 10 9 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) 7tm_2 PF00002.19 EMC81025.1 - 6.6e-74 248.0 26.2 9.5e-72 240.9 12.5 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC81025.1 - 0.039 13.9 0.2 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 Hormone receptor domain DUF2976 PF11190.3 EMC81025.1 - 2 7.9 6.3 21 4.7 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) TLV_coat PF00429.14 EMC81026.1 - 8.8e-08 31.0 0.7 1e-07 30.8 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC81026.1 - 0.00038 20.0 0.6 0.00051 19.6 0.4 1.2 1 0 0 1 1 1 1 Retroviral envelope protein CorA PF01544.13 EMC81026.1 - 0.015 14.3 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IBN_N PF03810.14 EMC81028.1 - 1.1e-20 73.2 0.8 8.1e-20 70.5 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EMC81028.1 - 0.0014 18.9 0.0 0.03 14.5 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats Xpo1 PF08389.7 EMC81028.1 - 0.036 13.9 0.0 0.036 13.9 0.0 5.1 6 0 0 6 6 6 0 Exportin 1-like protein HEAT_EZ PF13513.1 EMC81028.1 - 0.19 12.2 0.9 4.8 7.8 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat RrnaAD PF00398.15 EMC81029.1 - 3.1e-59 200.1 0.0 3.7e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMC81029.1 - 4.5e-10 39.5 0.0 7.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC81029.1 - 2.5e-07 31.2 0.0 7.5e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC81029.1 - 8.5e-06 25.4 0.0 7.2e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC81029.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMC81029.1 - 0.00017 21.2 0.1 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EMC81029.1 - 0.00072 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC81029.1 - 0.0025 18.2 0.0 0.0059 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMC81029.1 - 0.0046 16.5 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EMC81029.1 - 0.0053 16.3 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.7 EMC81029.1 - 0.0053 17.2 0.0 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC81029.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 EMC81029.1 - 0.017 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.13 EMC81029.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 EMC81029.1 - 0.029 13.9 0.0 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.6 EMC81029.1 - 0.099 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CMAS PF02353.15 EMC81029.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Kinesin PF00225.18 EMC81030.1 - 2.7e-94 315.6 0.1 6.7e-94 314.3 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain UPF0542 PF15086.1 EMC81031.1 - 2.6e-39 132.7 3.3 2.9e-39 132.6 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 7tm_1 PF00001.16 EMC81031.1 - 0.046 12.8 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SieB PF14163.1 EMC81031.1 - 0.079 12.5 0.2 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B OAD_gamma PF04277.8 EMC81031.1 - 0.12 12.7 0.5 0.15 12.4 0.3 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NDUFA12 PF05071.11 EMC81032.1 - 2e-05 24.9 2.4 2.2e-05 24.8 0.9 1.6 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF947 PF06102.7 EMC81032.1 - 0.021 14.6 1.5 0.028 14.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF947) WD40 PF00400.27 EMC81033.1 - 1.6e-34 116.5 9.2 3.5e-10 39.3 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC81033.1 - 0.001 17.3 4.3 0.088 10.9 0.2 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMC81033.1 - 0.058 11.6 0.3 0.52 8.5 0.2 2.3 1 1 0 1 1 1 0 Cytochrome D1 heme domain ELO PF01151.13 EMC81034.1 - 2.2e-62 210.6 25.8 2.6e-62 210.3 17.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DEP PF00610.16 EMC81035.1 - 5e-16 58.2 0.7 3.4e-15 55.5 0.0 2.5 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF148 PF02520.12 EMC81035.1 - 0.034 13.9 0.6 0.099 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 TniB PF05621.6 EMC81035.1 - 0.044 12.5 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RhoGAP PF00620.22 EMC81035.1 - 0.052 13.1 0.1 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain Ras PF00071.17 EMC81037.1 - 2.5e-61 205.8 2.2 3e-61 205.5 1.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81037.1 - 9.6e-20 71.2 0.1 1.5e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81037.1 - 3.3e-14 52.5 0.3 4.4e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC81037.1 - 4.8e-07 29.1 0.7 0.00017 20.8 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMC81037.1 - 6.6e-06 25.4 0.6 8.8e-06 25.0 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC81037.1 - 6.9e-05 22.3 0.1 0.00015 21.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMC81037.1 - 0.0024 17.1 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EMC81037.1 - 0.003 17.5 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ORC3_N PF07034.6 EMC81037.1 - 0.0037 16.2 0.2 0.0048 15.9 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Septin PF00735.13 EMC81037.1 - 0.017 14.1 0.2 0.63 9.0 0.0 2.2 2 0 0 2 2 2 0 Septin G-alpha PF00503.15 EMC81037.1 - 0.019 13.6 1.8 3.8 6.0 0.0 3.4 2 2 2 4 4 4 0 G-protein alpha subunit AAA_14 PF13173.1 EMC81037.1 - 0.063 13.1 0.2 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EMC81038.1 - 5.7e-72 241.9 0.0 9.5e-72 241.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81038.1 - 3.2e-39 134.5 0.0 5.7e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EMC81038.1 - 6.4e-38 128.5 1.6 1.2e-18 66.8 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EMC81038.1 - 9.2e-07 28.1 0.0 2e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC81038.1 - 0.02 14.6 1.2 0.84 9.3 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tcp10_C PF07202.8 EMC81038.1 - 0.047 13.2 0.1 0.51 9.8 0.1 2.1 1 1 0 1 1 1 0 T-complex protein 10 C-terminus ELM2 PF01448.19 EMC81039.1 - 1.8e-15 57.2 0.1 7.1e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 EMC81039.1 - 2.6e-05 24.1 0.2 5.4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SET PF00856.23 EMC81040.1 - 2.3e-05 24.7 1.1 8.7e-05 22.8 0.1 2.3 2 1 0 2 2 2 1 SET domain DUF4189 PF13827.1 EMC81041.1 - 0.1 12.8 2.7 1.8 8.8 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4189) DUF1880 PF08976.6 EMC81041.1 - 0.98 9.5 16.1 2.8 8.0 1.8 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF1880) CTD PF12815.2 EMC81041.1 - 2.3 8.6 12.9 4.1 7.8 8.9 1.5 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Guanylate_cyc PF00211.15 EMC81042.1 - 1.7e-37 128.5 0.0 1.5e-35 122.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 EMC81042.1 - 1.1e-05 24.7 0.8 1.7e-05 24.1 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.12 EMC81042.1 - 0.00095 18.3 0.0 0.0019 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase dsDNA_bind PF01984.15 EMC81042.1 - 0.029 14.3 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Cnd1 PF12717.2 EMC81042.1 - 0.091 12.6 1.3 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CARD PF00619.16 EMC81042.1 - 0.14 12.0 1.7 0.21 11.4 0.4 1.8 2 0 0 2 2 2 0 Caspase recruitment domain DUF2356 PF10189.4 EMC81043.1 - 1.9e-76 256.1 2.7 2.8e-76 255.5 0.3 2.0 2 0 0 2 2 2 1 Conserved protein (DUF2356) Ras PF00071.17 EMC81044.1 - 4.8e-40 136.5 0.0 7.5e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81044.1 - 5.1e-16 59.2 0.0 1.2e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81044.1 - 4.2e-08 32.6 0.0 5.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC81044.1 - 7.8e-05 22.1 0.0 0.00022 20.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC81044.1 - 0.00066 19.6 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC81044.1 - 0.0046 16.1 0.1 0.0061 15.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EMC81044.1 - 0.018 14.7 0.1 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 EMC81044.1 - 0.024 13.8 0.0 0.068 12.3 0.0 1.7 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMC81044.1 - 0.069 13.3 0.0 3.9 7.6 0.0 2.7 3 1 1 4 4 4 0 AAA domain AAA_14 PF13173.1 EMC81044.1 - 0.069 13.0 0.1 0.44 10.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain AICARFT_IMPCHas PF01808.13 EMC81044.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Globin PF00042.17 EMC81045.1 - 1.7e-24 86.2 0.1 3.2e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Globin DUF294_C PF10335.4 EMC81045.1 - 0.079 12.6 0.4 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain DUF4020 PF13212.1 EMC81045.1 - 0.11 12.0 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) Fox-1_C PF12414.3 EMC81046.1 - 4.8e-39 132.6 29.4 4e-38 129.7 18.9 3.1 2 1 0 2 2 2 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 EMC81046.1 - 7.5e-19 67.1 0.1 1.6e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC81046.1 - 2.2e-15 56.3 0.1 3.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC81046.1 - 7.2e-11 41.7 0.1 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECM1 PF05782.6 EMC81046.1 - 0.12 11.0 0.5 0.19 10.4 0.3 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) RRM_3 PF08777.6 EMC81046.1 - 0.16 11.8 1.1 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 RNA binding motif Thioredoxin PF00085.15 EMC81047.1 - 6.4e-29 99.6 0.1 7.7e-29 99.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMC81047.1 - 7e-09 35.8 0.0 4.2e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC81047.1 - 1.2e-06 28.3 0.1 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EMC81047.1 - 5e-05 23.3 0.0 0.0027 17.7 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 EMC81047.1 - 0.00021 21.0 0.1 0.0003 20.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 EMC81047.1 - 0.0026 17.4 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DSBA PF01323.15 EMC81047.1 - 0.012 15.1 0.0 0.29 10.6 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 EMC81047.1 - 0.018 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.9 EMC81047.1 - 0.051 13.8 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Redoxin PF08534.5 EMC81047.1 - 0.075 12.5 1.0 0.33 10.4 0.1 2.0 1 1 1 2 2 2 0 Redoxin Pyr_redox_3 PF13738.1 EMC81048.1 - 1.5e-38 132.8 0.0 2.7e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC81048.1 - 2.6e-08 33.9 0.0 7.6e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC81048.1 - 2.6e-08 33.1 0.0 1.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMC81048.1 - 1.5e-06 28.1 0.0 4.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMC81048.1 - 3.4e-06 25.8 0.0 0.0015 17.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 EMC81048.1 - 3.6e-06 26.1 0.0 0.00012 21.1 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FMO-like PF00743.14 EMC81048.1 - 1.2e-05 23.7 0.0 4.8e-05 21.7 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.19 EMC81048.1 - 0.00013 20.9 0.0 0.00035 19.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMC81048.1 - 0.00017 20.7 0.0 0.00035 19.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EMC81048.1 - 0.0002 20.5 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMC81048.1 - 0.00093 18.9 0.1 0.0022 17.7 0.1 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMC81048.1 - 0.0027 18.0 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C71 PF12386.3 EMC81048.1 - 0.044 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Amino_oxidase PF01593.19 EMC81048.1 - 0.048 12.7 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EMC81048.1 - 0.073 11.9 0.0 0.68 8.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EMC81048.1 - 0.12 12.6 0.0 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF313 PF03754.8 EMC81048.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF313) CYTH PF01928.16 EMC81048.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 CYTH domain PMP22_Claudin PF00822.15 EMC81049.1 - 8.1e-58 194.7 1.8 1.1e-57 194.3 1.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC81049.1 - 2.4e-21 76.1 0.9 4e-21 75.4 0.6 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 EMC81049.1 - 0.0049 16.1 0.0 0.0081 15.4 0.0 1.5 1 0 0 1 1 1 1 Tetraspanin family Ras PF00071.17 EMC81050.1 - 2.1e-35 121.5 0.0 2.4e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81050.1 - 4.8e-15 56.1 0.0 7.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81050.1 - 4.4e-05 22.7 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC81050.1 - 0.00011 21.7 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC81050.1 - 0.00024 21.0 0.0 0.00047 20.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Met_synt_B12 PF02965.12 EMC81050.1 - 0.048 12.8 0.0 3.2 6.8 0.0 2.1 1 1 1 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain EF-hand_1 PF00036.27 EMC81051.1 - 4.1e-10 38.2 3.9 1.8e-06 26.8 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC81051.1 - 8.7e-10 37.6 3.4 4.5e-07 29.2 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EMC81051.1 - 2.6e-08 32.8 3.6 9e-05 21.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC81051.1 - 4.2e-08 33.2 0.5 6e-08 32.7 0.4 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC81051.1 - 8.4e-08 31.7 2.1 0.00017 21.1 0.5 2.8 1 1 1 2 2 2 2 EF-hand domain pair EFhand_Ca_insen PF08726.5 EMC81051.1 - 0.078 12.9 0.8 0.23 11.4 0.0 2.0 2 1 1 3 3 3 0 Ca2+ insensitive EF hand PSP1 PF04468.7 EMC81052.1 - 0.019 14.9 0.3 0.053 13.5 0.1 1.8 2 0 0 2 2 2 0 PSP1 C-terminal conserved region PX PF00787.19 EMC81053.1 - 8.1e-18 64.2 0.0 1.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EMC81053.1 - 1.8e-16 59.5 2.3 6.2e-16 57.8 0.7 2.2 2 0 0 2 2 2 1 PB1 domain SH3_1 PF00018.23 EMC81053.1 - 2.3e-12 46.0 0.1 5.6e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC81053.1 - 2.8e-11 42.8 0.2 7.3e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC81053.1 - 1.7e-09 37.0 0.0 1.1e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain fn3 PF00041.16 EMC81054.1 - 5.3e-16 58.5 3.6 8.6e-09 35.4 0.0 4.8 4 2 1 5 5 5 3 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC81054.1 - 1.4e-12 47.6 5.4 4.7e-07 29.8 0.1 2.6 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding IL4Ra_N PF09238.5 EMC81054.1 - 7.8e-06 25.9 5.4 0.19 11.8 0.2 3.5 3 1 1 4 4 4 3 Interleukin-4 receptor alpha chain, N-terminal Tissue_fac PF01108.12 EMC81054.1 - 2.9e-05 23.7 6.5 0.00045 19.9 0.0 3.3 2 1 1 3 3 3 1 Tissue factor EpoR_lig-bind PF09067.5 EMC81054.1 - 4.5e-05 23.3 5.3 0.0016 18.3 0.0 2.8 3 0 0 3 3 3 2 Erythropoietin receptor, ligand binding IL12p40_C PF10420.4 EMC81054.1 - 0.14 12.2 2.2 4.9 7.3 0.1 2.8 2 1 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus Sugar_tr PF00083.19 EMC81055.1 - 1.1e-34 119.8 16.0 1.4e-34 119.4 11.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC81055.1 - 2.8e-31 108.5 44.4 5.4e-27 94.4 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TB2_DP1_HVA22 PF03134.14 EMC81056.1 - 1.1e-31 108.3 9.6 1.9e-31 107.6 6.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.4 EMC81056.1 - 0.049 13.7 0.2 0.088 12.9 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) PLAC9 PF15205.1 EMC81058.1 - 1.6e-15 57.0 0.1 1.7e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 Placenta-specific protein 9 LpxC PF03331.8 EMC81058.1 - 0.044 12.7 0.3 0.045 12.7 0.2 1.0 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase TRL PF13146.1 EMC81058.1 - 0.088 12.8 0.2 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 TRL-like protein family DUF1241 PF06840.6 EMC81058.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Rabaptin PF03528.10 EMC81058.1 - 0.12 12.2 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Rabaptin Annexin PF00191.15 EMC81059.1 - 8.9e-101 329.8 12.1 5.9e-26 90.1 0.2 4.1 4 0 0 4 4 4 4 Annexin PSP1 PF04468.7 EMC81061.1 - 0.019 14.9 0.3 0.053 13.5 0.1 1.8 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Cadherin PF00028.12 EMC81062.1 - 1.5e-92 303.9 1.8 2.7e-23 82.0 0.1 6.0 6 0 0 6 6 6 5 Cadherin domain Cadherin_C PF01049.12 EMC81062.1 - 7.5e-55 185.0 1.5 1.4e-54 184.1 1.0 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 EMC81062.1 - 6.3e-29 99.5 0.2 2.7e-28 97.5 0.1 2.1 2 0 0 2 2 2 1 Cadherin prodomain like He_PIG PF05345.7 EMC81062.1 - 0.00058 19.8 11.6 0.7 9.9 0.3 6.1 6 1 1 7 7 7 2 Putative Ig domain Cadherin_2 PF08266.7 EMC81062.1 - 0.0058 16.1 0.0 4.9 6.7 0.0 3.3 3 0 0 3 3 3 1 Cadherin-like DUF2207 PF09972.4 EMC81062.1 - 0.046 12.3 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Prok-E2_A PF14457.1 EMC81062.1 - 0.049 13.0 0.2 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family A SIT PF15330.1 EMC81062.1 - 0.17 12.0 0.1 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Big_3_4 PF13754.1 EMC81062.1 - 0.47 10.8 14.0 0.5 10.7 0.3 5.0 5 1 1 6 6 6 0 Bacterial Ig-like domain (group 3) Rifin_STEVOR PF02009.11 EMC81062.1 - 0.7 9.4 2.3 1.1 8.8 1.6 1.2 1 0 0 1 1 1 0 Rifin/stevor family Sulfotransfer_2 PF03567.9 EMC81064.1 - 2.3e-62 210.9 1.0 3.2e-62 210.4 0.7 1.2 1 0 0 1 1 1 1 Sulfotransferase family MIP PF00230.15 EMC81065.1 - 3.1e-72 242.7 14.4 3.8e-72 242.4 10.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein BTB_2 PF02214.17 EMC81066.1 - 2.2e-17 63.0 0.0 3.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.9 EMC81067.1 - 9.5e-59 198.8 9.0 1.5e-58 198.1 6.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.9 EMC81067.1 - 6.5e-37 125.0 3.2 2.8e-36 123.0 2.2 2.2 1 0 0 1 1 1 1 NHR1 homology to TAF zf-C2H2 PF00096.21 EMC81069.1 - 6.4e-52 170.8 224.5 0.00069 19.8 3.1 30.7 31 0 0 31 31 31 25 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81069.1 - 1.6e-49 162.6 203.8 0.0022 18.1 0.5 30.2 31 0 0 31 31 31 24 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC81069.1 - 2.6e-35 118.9 185.5 3.9e-06 26.8 0.6 30.2 33 0 0 33 33 33 19 Zinc-finger double domain zf-Di19 PF05605.7 EMC81069.1 - 1.9e-25 88.7 167.7 8e-05 22.6 2.3 19.7 16 3 4 20 20 20 12 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMC81069.1 - 1.7e-21 75.3 163.5 3.7e-05 23.4 0.3 25.2 27 1 1 28 28 28 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC81069.1 - 2.8e-16 59.1 155.3 0.00091 19.3 0.4 24.5 25 1 1 26 26 26 12 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC81069.1 - 6.8e-06 26.1 168.7 0.082 13.0 0.4 24.5 8 6 14 23 23 23 13 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC81069.1 - 0.00053 20.0 6.4 0.0074 16.4 0.8 22.5 25 0 0 25 25 25 9 Zinc-finger of C2H2 type 7tm_1 PF00001.16 EMC81071.1 - 1.1e-64 218.1 9.4 1.2e-64 217.9 6.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81071.1 - 4.6e-07 29.2 14.0 0.0018 17.5 5.8 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC81071.1 - 1.4e-05 24.3 9.5 1.4e-05 24.3 6.6 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.16 EMC81072.1 - 5.9e-63 212.3 11.7 6.9e-63 212.1 8.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81072.1 - 1.7e-07 30.6 14.0 0.00074 18.7 6.2 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC81072.1 - 3e-05 23.2 10.2 3e-05 23.2 7.1 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0029 PF01205.14 EMC81073.1 - 4.1e-33 113.3 0.0 6.4e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EMC81073.1 - 8.1e-18 64.3 0.3 1.8e-17 63.2 0.2 1.6 1 0 0 1 1 1 1 RWD domain Oxysterol_BP PF01237.13 EMC81074.1 - 4.6e-146 485.8 0.5 6.6e-146 485.3 0.3 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.25 EMC81074.1 - 7.3e-31 104.4 4.3 6.2e-11 41.5 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMC81074.1 - 7.5e-31 105.4 3.3 7.8e-14 51.3 0.2 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC81074.1 - 8.2e-29 99.7 3.0 8.8e-17 61.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC81074.1 - 1e-24 86.3 1.7 5.3e-06 26.7 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81074.1 - 6.8e-23 78.4 1.9 1.3e-06 28.0 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 EMC81074.1 - 0.0019 18.3 0.8 0.042 14.0 0.1 2.9 2 1 1 3 3 3 1 PH domain SHS2_FTSA PF02491.15 EMC81074.1 - 0.013 15.3 0.3 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA PH_11 PF15413.1 EMC81074.1 - 0.1 12.8 0.2 0.1 12.8 0.1 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain RIIa PF02197.12 EMC81075.1 - 1.9e-05 23.9 0.3 1.9e-05 23.9 0.2 2.2 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit DUF3808 PF10300.4 EMC81077.1 - 7.1e-131 436.9 7.1 8.4e-131 436.7 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Cohesin_load PF10345.4 EMC81077.1 - 2.2e-07 29.5 1.3 2.2e-07 29.5 0.9 2.0 2 1 0 2 2 2 1 Cohesin loading factor TPR_2 PF07719.12 EMC81077.1 - 7.2e-06 25.5 1.6 0.32 11.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC81077.1 - 0.00016 21.1 0.7 0.34 10.6 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC81077.1 - 0.00021 21.1 0.2 2.9 7.9 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC81077.1 - 0.0066 16.8 0.3 50 4.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC81077.1 - 0.016 14.9 0.5 0.35 10.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2724 PF10893.3 EMC81077.1 - 0.066 13.0 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) adh_short_C2 PF13561.1 EMC81078.1 - 9e-21 74.7 0.0 1e-20 74.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC81078.1 - 3.4e-12 46.6 0.1 4.3e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Pkinase PF00069.20 EMC81079.1 - 5.5e-65 219.0 0.0 7.2e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81079.1 - 3.6e-40 137.6 0.0 5.3e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 EMC81079.1 - 1.6e-12 46.8 0.2 3.4e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 EMC81079.1 - 5.6e-05 22.2 0.0 0.0016 17.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC81079.1 - 0.024 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMC81079.1 - 0.04 12.7 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Helicase_C_3 PF13625.1 EMC81080.1 - 2.5e-31 108.1 0.0 1.3e-30 105.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC81080.1 - 7.3e-15 55.2 0.0 2.8e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMC81080.1 - 3.9e-10 39.4 0.0 9.1e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC81080.1 - 2.2e-06 27.2 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EMC81080.1 - 9.5e-06 24.6 0.0 1.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain TUSC2 PF15000.1 EMC81080.1 - 0.025 14.6 0.5 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 Tumour suppressor candidate 2 DUF3890 PF13029.1 EMC81080.1 - 0.063 13.3 0.3 0.19 11.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) AAA_22 PF13401.1 EMC81080.1 - 0.083 13.0 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 EMC81081.1 - 3.3e-101 339.0 0.0 3.7e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.13 EMC81082.1 - 4.7e-53 180.0 12.3 6.2e-53 179.6 8.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EMC81082.1 - 9.9e-12 44.2 0.1 3.7e-11 42.4 0.1 1.9 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC81082.1 - 3.6e-07 29.4 0.2 9.8e-07 28.0 0.1 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC81082.1 - 2.8e-06 26.7 0.0 6.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IFT57 PF10498.4 EMC81082.1 - 0.00089 18.0 5.2 0.013 14.3 0.6 2.3 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 FliS PF02561.9 EMC81082.1 - 0.12 12.2 3.2 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliS HD_3 PF13023.1 EMC81082.1 - 0.16 11.6 5.1 1.6 8.4 0.2 2.3 2 0 0 2 2 2 0 HD domain V-SNARE PF05008.10 EMC81082.1 - 0.28 11.3 5.3 1.2 9.3 0.1 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.7 EMC81082.1 - 0.44 10.3 2.1 14 5.4 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mit_KHE1 PF10173.4 EMC81082.1 - 0.6 9.9 3.8 0.9 9.3 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related IncA PF04156.9 EMC81082.1 - 2.3 7.7 6.6 13 5.3 0.1 2.3 2 0 0 2 2 2 0 IncA protein Laminin_II PF06009.7 EMC81082.1 - 2.9 7.6 6.6 3.7 7.3 0.8 2.5 2 1 0 2 2 2 0 Laminin Domain II PTS_IIA PF02255.11 EMC81082.1 - 3.3 7.6 6.8 11 5.9 0.9 2.7 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit KxDL PF10241.4 EMC81082.1 - 5 7.1 10.1 1.7 8.6 1.8 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein BLOC1_2 PF10046.4 EMC81082.1 - 5.4 7.2 9.4 0.44 10.7 1.8 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Protocadherin PF08374.6 EMC81083.1 - 0.0032 17.1 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Protocadherin Syndecan PF01034.15 EMC81083.1 - 0.0032 17.0 0.1 0.0043 16.6 0.1 1.2 1 0 0 1 1 1 1 Syndecan domain Spore_SspJ PF09575.5 EMC81083.1 - 0.0033 17.5 0.3 0.0045 17.1 0.2 1.2 1 0 0 1 1 1 1 Small spore protein J (Spore_SspJ) EphA2_TM PF14575.1 EMC81083.1 - 0.0058 16.9 0.0 0.0069 16.7 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMC81083.1 - 0.012 15.8 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRR19-TM PF15176.1 EMC81083.1 - 0.027 14.1 0.0 0.028 14.1 0.0 1.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain OAD_gamma PF04277.8 EMC81083.1 - 0.039 14.3 0.1 0.059 13.7 0.1 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Baculo_11_kDa PF06143.6 EMC81083.1 - 0.041 13.2 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Chordopox_A13L PF05961.6 EMC81083.1 - 0.056 13.3 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein MFS_2 PF13347.1 EMC81083.1 - 0.075 11.4 0.0 0.088 11.1 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein ODV-E18 PF10717.4 EMC81083.1 - 0.089 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Herpes_gE PF02480.11 EMC81083.1 - 0.096 10.9 0.0 0.096 10.9 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E m04gp34like PF12216.3 EMC81083.1 - 0.097 12.0 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein Adeno_E3_CR2 PF02439.10 EMC81083.1 - 0.49 9.9 6.8 0.76 9.3 4.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2970 PF11174.3 EMC81083.1 - 5.8 6.5 7.4 8.5 6.0 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) 7tm_4 PF13853.1 EMC81084.1 - 5.7e-54 181.8 13.2 5.7e-54 181.8 9.1 2.0 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC81084.1 - 2e-22 79.5 17.7 2.7e-22 79.1 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MHYT PF03707.11 EMC81084.1 - 0.14 12.3 0.2 0.14 12.3 0.2 3.7 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat adh_short_C2 PF13561.1 EMC81085.1 - 7e-16 58.7 0.0 8e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cu_amine_oxid PF01179.15 EMC81086.1 - 3.2e-115 385.1 0.0 4e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain zf-H2C2_2 PF13465.1 EMC81087.1 - 1.2e-84 274.7 76.3 5e-10 39.1 0.3 11.0 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.21 EMC81087.1 - 1.8e-69 226.0 85.0 3.9e-07 30.0 0.2 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81087.1 - 3.1e-43 142.9 73.1 1.1e-05 25.4 0.4 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC81087.1 - 1e-26 91.9 69.2 0.00012 21.8 0.0 10.8 10 1 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC81087.1 - 4e-25 87.2 37.3 1.5e-05 24.9 0.1 10.1 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC81087.1 - 2e-14 53.2 63.2 0.0014 18.7 0.2 10.1 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC81087.1 - 1.2e-11 44.5 48.9 0.00033 20.7 1.2 7.2 3 2 0 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-IS66 PF13005.2 EMC81087.1 - 2.5e-07 30.5 25.8 5 7.1 0.1 9.8 10 0 0 10 10 10 0 zinc-finger binding domain of transposase IS66 FYDLN_acid PF09538.5 EMC81087.1 - 2.7e-07 31.1 24.6 5.5 7.6 0.1 9.2 2 2 7 9 9 9 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.17 EMC81087.1 - 3.9e-07 29.6 32.4 0.13 11.9 1.4 6.9 1 1 8 9 9 9 5 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EMC81087.1 - 8.1e-07 28.8 54.1 0.076 12.9 3.2 9.2 3 3 7 10 10 10 4 Zinc ribbon domain Prok-RING_1 PF14446.1 EMC81087.1 - 2.7e-06 26.9 24.7 16 5.2 0.0 9.7 10 0 0 10 10 10 0 Prokaryotic RING finger family 1 Elf1 PF05129.8 EMC81087.1 - 3.6e-06 26.5 38.3 0.11 12.2 0.3 6.8 1 1 5 6 6 6 4 Transcription elongation factor Elf1 like zf-ISL3 PF14690.1 EMC81087.1 - 3.2e-05 23.8 53.2 1.2 9.1 0.7 10.1 10 0 0 10 10 10 3 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-AN1 PF01428.11 EMC81087.1 - 5.5e-05 22.9 54.3 1.2 9.1 2.5 10.1 8 1 2 10 10 10 2 AN1-like Zinc finger LIM PF00412.17 EMC81087.1 - 6.7e-05 22.8 47.1 0.4 10.7 6.1 8.4 3 3 4 7 7 7 3 LIM domain zf-trcl PF13451.1 EMC81087.1 - 0.0014 18.1 38.3 0.78 9.4 0.1 9.1 10 0 0 10 10 10 2 Probable zinc-binding domain zf-LYAR PF08790.6 EMC81087.1 - 0.0015 18.2 50.7 0.2 11.4 1.7 9.5 10 0 0 10 10 10 3 LYAR-type C2HC zinc finger zf-RING_3 PF14369.1 EMC81087.1 - 0.0025 17.7 47.7 4.5 7.3 0.2 9.7 9 1 1 10 10 10 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 EMC81087.1 - 0.0045 16.7 57.8 0.48 10.2 3.1 6.8 3 3 4 7 7 7 3 Transposase zinc-ribbon domain CpXC PF14353.1 EMC81087.1 - 0.006 16.5 39.4 4.1 7.3 1.0 9.2 4 4 3 7 7 7 1 CpXC protein HypA PF01155.14 EMC81087.1 - 0.047 13.3 33.9 0.96 9.1 0.5 5.9 1 1 5 6 6 6 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 EMC81087.1 - 0.1 12.5 38.1 6 6.9 0.8 6.8 1 1 7 8 8 8 0 TFIIH C1-like domain Siva PF05458.7 EMC81087.1 - 0.17 11.4 10.7 1.5 8.3 0.2 3.4 1 1 2 3 3 3 0 Cd27 binding protein (Siva) YhfH PF14149.1 EMC81087.1 - 0.26 11.1 36.1 7.5 6.4 0.2 8.4 9 0 0 9 9 9 0 YhfH-like protein DUF164 PF02591.10 EMC81087.1 - 0.97 9.3 29.3 14 5.6 0.0 8.7 10 0 0 10 10 10 0 Putative zinc ribbon domain RRN7 PF11781.3 EMC81087.1 - 1.1 8.8 30.6 2.4 7.7 0.0 8.3 10 0 0 10 10 10 0 RNA polymerase I-specific transcription initiation factor Rrn7 GAGA PF09237.6 EMC81087.1 - 1.3 8.6 28.3 1 8.9 0.0 6.8 1 1 6 8 8 8 0 GAGA factor zinc_ribbon_5 PF13719.1 EMC81087.1 - 1.5 8.4 45.6 10 5.8 2.9 9.5 9 1 0 9 9 9 0 zinc-ribbon domain DUF2321 PF10083.4 EMC81087.1 - 1.6 8.2 25.2 9.5 5.6 1.7 5.2 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2321) DNA_RNApol_7kD PF03604.8 EMC81087.1 - 3.1 7.3 33.3 1.5 8.3 0.6 8.5 10 0 0 10 10 9 0 DNA directed RNA polymerase, 7 kDa subunit Scramblase PF03803.10 EMC81087.1 - 3.2 6.7 6.7 33 3.4 0.1 3.5 1 1 2 4 4 4 0 Scramblase zf-C4_ClpX PF06689.8 EMC81087.1 - 3.6 7.1 25.5 12 5.4 0.2 7.0 7 1 0 7 7 7 0 ClpX C4-type zinc finger Sgf11 PF08209.6 EMC81087.1 - 3.8 6.9 38.7 5.5 6.4 0.0 9.6 10 0 0 10 10 10 0 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.1 EMC81087.1 - 9.8 5.5 51.4 4.1 6.7 0.3 9.9 10 0 0 10 10 10 0 zinc-ribbon domain VWD PF00094.20 EMC81088.1 - 5.6e-10 39.6 0.0 6.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type D domain VWD PF00094.20 EMC81089.1 - 1.2e-05 25.5 0.3 1.9e-05 24.9 0.1 1.4 2 0 0 2 2 2 1 von Willebrand factor type D domain VWD PF00094.20 EMC81090.1 - 1.3e-27 96.9 0.0 2.2e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 EMC81090.1 - 4.2e-19 68.5 12.1 4.2e-19 68.5 8.4 2.7 4 0 0 4 4 4 1 C8 domain Pacifastin_I PF05375.8 EMC81090.1 - 0.01 15.3 8.8 0.01 15.3 6.1 3.0 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) 7tm_4 PF13853.1 EMC81092.1 - 2.1e-52 176.7 13.8 2.1e-52 176.7 9.6 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC81092.1 - 6.9e-25 87.6 23.9 1.1e-24 87.0 16.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC81093.1 - 4.5e-12 45.6 1.7 4.5e-12 45.6 1.2 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC81094.1 - 3.3e-05 23.1 0.2 5e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AA_permease_2 PF13520.1 EMC81096.1 - 1.9e-26 92.5 0.6 2.2e-26 92.3 0.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC81096.1 - 4.2e-18 64.9 0.2 5.1e-18 64.6 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease 7tm_1 PF00001.16 EMC81097.1 - 2.2e-08 33.5 0.1 3.1e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC81099.1 - 6.1e-06 25.5 0.4 9.5e-05 21.6 0.1 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC81099.1 - 0.059 13.1 0.3 0.059 13.1 0.2 1.9 2 1 1 3 3 3 0 Olfactory receptor 7tm_4 PF13853.1 EMC81100.1 - 1.3e-40 138.5 15.9 1.3e-40 138.5 11.0 2.2 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC81100.1 - 3.3e-23 82.1 23.7 4.6e-23 81.6 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC81101.1 - 3.5e-24 85.2 6.0 4.1e-24 85.0 4.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC81101.1 - 0.0025 16.9 1.8 0.003 16.7 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Integrase_Zn PF02022.14 EMC81102.1 - 1.3e-10 40.5 0.5 1.3e-10 40.5 0.4 2.0 2 0 0 2 2 2 1 Integrase Zinc binding domain RNase_H PF00075.19 EMC81102.1 - 0.00085 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 RNase H DUF2313 PF10076.4 EMC81102.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) DUF4620 PF15399.1 EMC81102.1 - 0.34 11.0 3.4 0.61 10.2 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4620) Sad1_UNC PF07738.8 EMC81103.1 - 1.2e-33 115.7 0.0 1.6e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CHGN PF05679.11 EMC81104.1 - 3.2e-144 481.3 0.0 7.1e-142 473.6 0.0 2.1 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 EMC81104.1 - 2e-10 40.3 0.0 3.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Fringe-like Homeobox PF00046.24 EMC81106.1 - 1.7e-25 88.3 6.0 1.9e-25 88.2 4.2 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC81106.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 EMC81106.1 - 0.14 11.2 0.4 0.16 11.0 0.3 1.4 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez ArfGap PF01412.13 EMC81107.1 - 1.4e-38 131.2 0.0 2.6e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Miro PF08477.8 EMC81107.1 - 3.3e-23 82.4 0.0 6.3e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMC81107.1 - 9.7e-18 64.0 0.0 3.2e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Ras family PH PF00169.24 EMC81107.1 - 3.3e-10 40.0 0.1 3.5e-09 36.7 0.0 2.7 2 1 0 2 2 2 1 PH domain Ank_4 PF13637.1 EMC81107.1 - 2.1e-05 24.9 0.0 5.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PH_6 PF15406.1 EMC81107.1 - 0.0022 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EMC81107.1 - 0.0049 17.0 0.0 0.45 10.7 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain DUF1830 PF08865.6 EMC81107.1 - 0.099 12.2 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Guanylate_kin PF00625.16 EMC81109.1 - 2.2e-68 229.2 0.0 2.6e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EMC81109.1 - 1.6e-06 28.4 0.0 3.3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC81109.1 - 6e-06 26.3 0.1 1.3e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC81109.1 - 1.3e-05 25.2 0.2 0.00012 22.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC81109.1 - 1.8e-05 25.5 0.1 4.2e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC81109.1 - 3.6e-05 23.6 0.0 0.00012 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMC81109.1 - 4.1e-05 23.8 0.0 6.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 EMC81109.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EMC81109.1 - 0.00013 21.8 0.1 0.00034 20.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EMC81109.1 - 0.00017 20.8 0.1 0.00023 20.4 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMC81109.1 - 0.0012 18.0 0.1 0.0031 16.6 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EMC81109.1 - 0.0015 18.0 0.4 0.0068 15.8 0.3 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EMC81109.1 - 0.0025 17.3 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EMC81109.1 - 0.0026 17.4 0.6 0.0088 15.7 0.4 1.8 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EMC81109.1 - 0.0032 17.1 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 EMC81109.1 - 0.0051 16.2 0.1 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EMC81109.1 - 0.0052 16.5 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.17 EMC81109.1 - 0.0055 16.8 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Miro PF08477.8 EMC81109.1 - 0.0062 17.0 0.1 0.0092 16.4 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein KAP_NTPase PF07693.9 EMC81109.1 - 0.011 14.8 0.0 0.013 14.4 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA PF00004.24 EMC81109.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EMC81109.1 - 0.012 14.6 0.1 0.4 9.6 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EMC81109.1 - 0.016 15.1 0.1 0.024 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EMC81109.1 - 0.028 14.3 1.1 0.15 11.9 0.7 1.9 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMC81109.1 - 0.033 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EMC81109.1 - 0.041 13.4 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4297 PF14130.1 EMC81109.1 - 0.045 13.6 0.2 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4297) Dynamin_N PF00350.18 EMC81109.1 - 0.05 13.4 0.2 0.063 13.0 0.1 1.6 1 1 0 1 1 1 0 Dynamin family AAA_19 PF13245.1 EMC81109.1 - 0.051 13.3 0.2 0.12 12.1 0.0 1.7 2 0 0 2 2 1 0 Part of AAA domain AAA_5 PF07728.9 EMC81109.1 - 0.052 13.2 0.3 0.27 10.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EMC81109.1 - 0.06 12.8 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EMC81109.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EMC81109.1 - 0.075 13.3 3.9 0.72 10.1 2.7 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMC81109.1 - 0.076 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mitoc_L55 PF09776.4 EMC81110.1 - 1.4e-30 105.1 0.1 1.6e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 TFIIF_alpha PF05793.7 EMC81111.1 - 0.028 12.7 24.0 0.028 12.8 16.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 EMC81111.1 - 0.17 11.7 15.6 0.18 11.7 10.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 EMC81111.1 - 0.18 11.4 32.8 0.22 11.1 22.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Herpes_DNAp_acc PF04929.7 EMC81111.1 - 0.31 9.9 15.5 0.32 9.9 10.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.7 EMC81111.1 - 0.48 10.2 20.2 0.56 10.0 14.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.6 EMC81111.1 - 0.95 8.9 17.1 1 8.8 11.9 1.1 1 0 0 1 1 1 0 PPP4R2 MIP-T3 PF10243.4 EMC81111.1 - 1.1 7.6 31.7 1.2 7.5 22.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 EMC81111.1 - 1.1 8.9 11.8 1.2 8.8 8.2 1.2 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 EMC81111.1 - 1.5 7.9 20.0 1.7 7.7 13.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) FGF-BP1 PF06473.7 EMC81111.1 - 2 7.9 16.1 2.8 7.4 11.2 1.4 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) YqfQ PF14181.1 EMC81111.1 - 2.7 8.0 19.9 3.6 7.5 13.8 1.3 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 EMC81111.1 - 2.8 7.2 23.8 3.4 6.9 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 EMC81111.1 - 3 6.5 15.8 3.2 6.5 11.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PDCD2_C PF04194.8 EMC81111.1 - 3.3 7.2 9.4 5.1 6.6 6.5 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Paramyxo_ncap PF00973.14 EMC81111.1 - 3.6 6.1 10.9 3.8 6.0 7.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2413 PF10310.4 EMC81111.1 - 4.6 5.9 19.6 4.9 5.8 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) BTV_NS2 PF04514.7 EMC81111.1 - 7 5.4 16.0 7.5 5.3 11.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF3807 PF12720.2 EMC81111.1 - 9.5 6.3 22.6 13 5.9 15.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Arf PF00025.16 EMC81113.1 - 5.2e-30 103.9 0.0 5.6e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC81113.1 - 0.00076 18.7 0.0 0.00085 18.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit wnt PF00110.14 EMC81114.1 - 1.8e-98 329.5 21.1 2e-98 329.4 14.6 1.0 1 0 0 1 1 1 1 wnt family Yae1_N PF09811.4 EMC81115.1 - 2.5e-11 42.8 40.0 1.5e+04 -4.9 27.7 3.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal wnt PF00110.14 EMC81116.1 - 1.2e-99 333.4 25.8 1.4e-99 333.2 17.9 1.0 1 0 0 1 1 1 1 wnt family Clr5 PF14420.1 EMC81116.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain SNARE PF05739.14 EMC81117.1 - 3e-08 33.2 7.6 5.2e-08 32.4 2.2 2.4 2 0 0 2 2 2 1 SNARE domain GRAM PF02893.15 EMC81117.1 - 0.035 13.6 0.0 0.079 12.4 0.0 1.7 1 0 0 1 1 1 0 GRAM domain DUF1664 PF07889.7 EMC81117.1 - 0.54 10.0 3.7 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cupin_8 PF13621.1 EMC81118.1 - 2.9e-24 85.9 2.0 4.5e-24 85.3 1.4 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EMC81118.1 - 5.6e-20 71.6 0.1 1.3e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EMC81118.1 - 0.042 13.0 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein MORN PF02493.15 EMC81119.1 - 1.6e-21 74.6 38.1 9.9e-07 28.1 3.3 9.0 8 1 0 8 8 8 7 MORN repeat VPS9 PF02204.13 EMC81119.1 - 8e-16 57.9 0.1 1.9e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Shisa PF13908.1 EMC81120.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EMC81120.1 - 0.015 13.6 0.0 0.015 13.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WBP-1 PF11669.3 EMC81120.1 - 0.02 14.9 0.2 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 FAM163 PF15069.1 EMC81120.1 - 0.085 13.4 0.0 0.095 13.2 0.0 1.2 1 0 0 1 1 1 0 FAM163 family Trp_oprn_chp PF09534.5 EMC81120.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UPF0239 PF06783.6 EMC81120.1 - 3.5 7.6 5.2 68 3.4 3.6 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) EF-hand_6 PF13405.1 EMC81121.1 - 5.3e-10 38.3 0.0 0.0085 15.9 0.0 4.5 5 1 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 EMC81121.1 - 1.3e-07 30.3 1.9 0.02 14.1 0.0 4.9 5 1 1 6 6 6 3 EF hand EF-hand_7 PF13499.1 EMC81121.1 - 2.7e-07 30.6 0.3 3.1e-06 27.2 0.2 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC81121.1 - 0.0032 17.0 0.8 1 9.0 0.0 3.0 1 1 1 2 2 2 2 EF-hand domain pair DUF2267 PF10025.4 EMC81121.1 - 0.011 15.7 0.4 0.055 13.5 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) 7tm_2 PF00002.19 EMC81122.1 - 6.6e-87 290.6 15.4 8.4e-87 290.2 10.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC81122.1 - 8.6e-19 67.3 2.2 1.6e-18 66.4 1.5 1.5 1 0 0 1 1 1 1 Hormone receptor domain cwf18 PF08315.7 EMC81123.1 - 6.4e-37 126.9 14.9 7.4e-37 126.6 10.3 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Arg_tRNA_synt_N PF03485.11 EMC81123.1 - 0.002 18.6 1.0 0.0036 17.8 0.7 1.3 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF1819 PF08849.6 EMC81123.1 - 0.05 12.9 0.2 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) HEAT_2 PF13646.1 EMC81123.1 - 0.061 13.6 0.5 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 HEAT repeats Cathelicidins PF00666.12 EMC81124.1 - 2.7e-13 49.8 0.1 3.9e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Cathelicidin Cathelicidins PF00666.12 EMC81125.1 - 1.2e-13 50.9 0.3 2.1e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Cathelicidin Cathelicidins PF00666.12 EMC81126.1 - 0.24 11.5 2.7 11 6.1 0.1 2.3 1 1 1 2 2 2 0 Cathelicidin FAST_1 PF06743.10 EMC81127.1 - 9.3e-27 92.5 3.6 1.4e-20 72.7 0.1 4.0 4 0 0 4 4 4 2 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 EMC81127.1 - 3.8e-21 75.2 0.0 1e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 NAC PF01849.13 EMC81128.1 - 5.4e-21 73.8 0.1 6.6e-20 70.3 0.0 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EMC81128.1 - 0.00095 18.9 0.2 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Ufm1 PF03671.9 EMC81128.1 - 0.056 13.1 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein RNA_pol_Rpo13 PF12136.3 EMC81128.1 - 0.082 12.6 5.7 0.14 11.8 3.9 1.4 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Creb_binding PF09030.5 EMC81129.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Creb binding DUF2348 PF09807.4 EMC81130.1 - 3e-100 334.4 0.6 3.4e-100 334.2 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) SWIRM PF04433.12 EMC81131.1 - 6.3e-34 115.9 2.3 9.6e-34 115.3 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EMC81131.1 - 2.8e-09 36.8 0.9 6e-09 35.8 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC81131.1 - 5.8e-08 32.7 0.0 1.8e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRCT PF00533.21 EMC81131.1 - 0.0094 16.0 0.0 0.71 10.0 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF2618 PF10940.3 EMC81131.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) Tubulin-binding PF00418.14 EMC81132.1 - 1.6e-45 152.4 24.1 1.3e-17 63.1 3.9 3.1 3 0 0 3 3 3 3 Tau and MAP protein, tubulin-binding repeat UK PF02512.9 EMC81132.1 - 0.17 12.3 1.4 1 9.8 0.1 2.3 1 1 2 3 3 3 0 Virulence determinant SPRY PF00622.23 EMC81134.1 - 1.3e-23 83.3 0.0 1.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 EMC81134.1 - 9.6e-21 73.0 0.1 1.7e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain Collagen PF01391.13 EMC81135.1 - 4.2e-19 67.8 34.9 2.2e-10 39.9 9.8 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Galanin PF01296.13 EMC81135.1 - 0.1 12.4 4.8 39 4.1 0.1 4.0 1 1 5 6 6 6 0 Galanin V-set PF07686.12 EMC81136.1 - 1e-10 41.4 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC81136.1 - 0.054 13.6 0.1 0.072 13.2 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC81137.1 - 2.4e-17 62.8 0.0 2.7e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC81137.1 - 0.01 15.9 1.2 0.062 13.4 0.8 2.1 1 1 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.1 EMC81137.1 - 0.031 14.7 0.2 0.11 13.0 0.1 1.8 1 1 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.1 EMC81137.1 - 0.049 13.7 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC81138.1 - 2.8e-18 65.8 0.0 3.2e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC81138.1 - 0.00023 21.6 0.3 0.0014 19.1 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC81138.1 - 0.00064 19.7 0.8 0.0054 16.8 0.5 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC81138.1 - 0.0021 18.1 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain BNR PF02012.15 EMC81138.1 - 4.9 7.3 5.1 19 5.5 0.1 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat Elong-fact-P_C PF09285.6 EMC81139.1 - 0.013 14.7 3.2 5.3 6.4 0.2 3.2 1 1 2 3 3 3 0 Elongation factor P, C-terminal PAS_10 PF13596.1 EMC81139.1 - 0.12 12.6 0.6 3.1 8.1 0.1 2.4 1 1 1 2 2 2 0 PAS domain Thyroglobulin_1 PF00086.13 EMC81139.1 - 0.76 9.1 8.2 60 3.0 5.7 3.1 1 1 0 1 1 1 0 Thyroglobulin type-1 repeat PMG PF05287.7 EMC81139.1 - 1.9 8.3 21.1 11 5.7 14.5 2.0 1 1 0 1 1 1 0 PMG protein C1-set PF07654.10 EMC81140.1 - 2.3e-42 142.8 0.1 5.2e-17 61.6 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC81140.1 - 1.6e-14 53.5 1.2 0.0019 18.0 0.0 4.8 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 EMC81140.1 - 2.6e-13 49.8 2.0 0.009 16.1 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 EMC81140.1 - 3e-10 40.0 8.3 0.00068 19.7 0.2 4.2 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 EMC81140.1 - 9.5e-09 35.6 11.6 0.039 14.4 0.2 4.5 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.11 EMC81140.1 - 1.1e-08 34.7 0.1 0.32 10.8 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain C1-set PF07654.10 EMC81141.1 - 1.7e-51 172.1 0.0 1.2e-18 66.8 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC81141.1 - 7.7e-13 48.1 0.3 0.027 14.3 0.1 4.3 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 EMC81141.1 - 2.3e-08 34.4 8.4 0.3 11.6 0.0 5.5 3 2 3 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.1 EMC81141.1 - 5e-07 29.7 0.4 0.97 9.5 0.0 4.3 3 1 1 4 4 4 3 Immunoglobulin domain ig PF00047.20 EMC81141.1 - 6e-05 23.0 4.4 1.1 9.4 0.0 4.8 5 1 0 5 5 5 2 Immunoglobulin domain I-set PF07679.11 EMC81141.1 - 0.00016 21.4 0.0 2.6 7.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain C1-set PF07654.10 EMC81142.1 - 1.7e-19 69.5 0.0 2e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 EMC81142.1 - 0.00017 21.6 0.0 0.00021 21.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC81142.1 - 0.00021 21.7 0.2 0.00044 20.6 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC81142.1 - 0.00052 19.8 0.0 0.00072 19.4 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC81142.1 - 0.00064 19.7 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain PT PF04886.7 EMC81143.1 - 6.7e-34 114.9 99.6 1.4e-09 37.1 9.7 8.2 2 2 3 5 5 5 5 PT repeat DUF1387 PF07139.6 EMC81144.1 - 6.8e-104 347.6 15.6 6.8e-104 347.6 10.8 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1387) CUE PF02845.11 EMC81144.1 - 0.066 12.7 0.1 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 CUE domain TMPIT PF07851.8 EMC81144.1 - 6.8 5.6 6.3 1 8.3 0.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein Mtr2 PF10429.4 EMC81145.1 - 0.0068 16.1 0.1 0.0079 15.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Shugoshin_C PF07557.6 EMC81146.1 - 1.2e-07 31.0 0.6 1.2e-07 31.0 0.4 1.6 2 0 0 2 2 2 1 Shugoshin C terminus RCSD PF05177.7 EMC81146.1 - 0.094 13.2 5.2 0.15 12.5 3.6 1.3 1 0 0 1 1 1 0 RCSD region Ald_Xan_dh_C2 PF02738.13 EMC81147.1 - 4.1e-196 652.5 0.0 5.6e-196 652.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EMC81147.1 - 1.4e-44 151.5 0.0 2.9e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EMC81147.1 - 6.9e-33 113.0 2.3 6.9e-33 113.0 1.6 1.8 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EMC81147.1 - 1.2e-28 98.8 0.8 3e-28 97.5 0.5 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 EMC81147.1 - 1.5e-25 89.1 0.0 2.1e-24 85.4 0.0 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 EMC81147.1 - 8.9e-09 34.9 0.1 8.9e-09 34.9 0.0 3.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain W2 PF02020.13 EMC81148.1 - 6.8e-23 80.4 11.9 2e-22 78.9 2.1 3.4 3 0 0 3 3 3 2 eIF4-gamma/eIF5/eIF2-epsilon Pkinase PF00069.20 EMC81149.1 - 2.2e-08 33.5 0.1 2.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pro_isomerase PF00160.16 EMC81150.1 - 5.8e-52 176.0 0.1 6.5e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NIF3 PF01784.13 EMC81151.1 - 4.4e-34 118.1 0.0 5.1e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4503 PF14951.1 EMC81151.1 - 0.014 13.5 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) ORC2 PF04084.9 EMC81152.1 - 8.2e-109 363.3 1.1 1.2e-108 362.8 0.8 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Hyccin PF09790.4 EMC81153.1 - 1.4e-131 437.9 0.0 1.8e-131 437.6 0.0 1.1 1 0 0 1 1 1 1 Hyccin NDUF_B12 PF08122.7 EMC81154.1 - 2.2e-21 75.3 0.2 3e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DED PF01335.16 EMC81155.1 - 2.2e-39 133.4 16.2 2.3e-23 82.0 0.5 3.6 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.17 EMC81155.1 - 5.1e-15 55.8 0.0 7.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EMC81156.1 - 7.4e-32 110.9 0.0 5.8e-31 108.0 0.0 2.1 1 1 0 1 1 1 1 Caspase domain DED PF01335.16 EMC81156.1 - 4.4e-31 106.8 20.1 2.5e-16 59.5 2.7 3.1 3 0 0 3 3 3 2 Death effector domain NOB1_Zn_bind PF08772.6 EMC81156.1 - 0.031 14.0 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Lact-deh-memb PF09330.6 EMC81156.1 - 0.041 13.2 0.3 0.068 12.5 0.2 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding DED PF01335.16 EMC81157.1 - 1.4e-40 137.2 15.5 2.3e-21 75.6 1.1 3.2 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.17 EMC81157.1 - 1.6e-33 116.4 0.1 3.8e-33 115.2 0.0 1.6 2 0 0 2 2 2 1 Caspase domain bcl-2I13 PF12201.3 EMC81157.1 - 0.14 11.6 0.5 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Bcl2-interacting killer, BH3-domain containing Peptidase_C14 PF00656.17 EMC81158.1 - 2.4e-41 142.0 0.0 3.5e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DED PF01335.16 EMC81158.1 - 1.4e-40 137.3 18.7 5.6e-22 77.6 3.1 2.6 3 0 0 3 3 3 2 Death effector domain L27 PF02828.11 EMC81158.1 - 0.057 13.1 0.9 0.52 10.0 0.3 2.4 2 0 0 2 2 2 0 L27 domain YihI PF04220.7 EMC81158.1 - 0.11 11.7 0.8 0.2 10.9 0.6 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) PYRIN PF02758.11 EMC81158.1 - 2.3 7.9 7.4 0.99 9.1 1.0 2.7 2 1 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Pkinase PF00069.20 EMC81159.1 - 3.4e-35 121.4 0.0 6e-35 120.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81159.1 - 1.1e-28 99.9 0.0 1.2e-24 86.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC81159.1 - 0.005 15.8 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EBP PF05241.7 EMC81159.1 - 0.059 12.3 0.3 0.091 11.7 0.2 1.2 1 0 0 1 1 1 0 Emopamil binding protein TMEM237 PF15383.1 EMC81160.1 - 4.9e-95 317.4 0.0 6.3e-95 317.1 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 237 RCC1 PF00415.13 EMC81161.1 - 2e-43 146.3 15.8 1.6e-12 47.3 0.1 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC81161.1 - 4.7e-28 96.1 31.4 9.5e-10 37.8 1.6 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.15 EMC81161.1 - 4e-25 85.9 30.3 2e-05 24.0 0.3 9.4 8 1 0 8 8 8 7 MORN repeat VPS9 PF02204.13 EMC81161.1 - 7.2e-23 80.6 0.1 4.3e-22 78.0 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RhoGEF PF00621.15 EMC81161.1 - 2.2e-05 24.4 1.4 5.5e-05 23.1 1.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EMC81161.1 - 0.0052 16.9 0.1 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 PH domain YoaP PF14268.1 EMC81161.1 - 0.15 11.3 0.1 0.37 10.0 0.0 1.6 1 0 0 1 1 1 0 YoaP-like Rad60-SLD PF11976.3 EMC81162.1 - 5e-23 80.5 0.2 6.1e-23 80.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMC81162.1 - 2.2e-17 62.2 0.6 2.6e-17 61.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Nop PF01798.13 EMC81163.1 - 8.4e-60 200.4 0.4 1.8e-59 199.3 0.3 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMC81163.1 - 1.5e-28 98.3 0.0 3.1e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMC81163.1 - 1.7e-24 85.7 2.2 4.5e-24 84.3 1.6 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain HD_3 PF13023.1 EMC81163.1 - 0.084 12.6 3.1 0.065 12.9 0.4 2.1 2 0 0 2 2 2 0 HD domain tRNA-synt_His PF13393.1 EMC81163.1 - 0.14 11.2 1.7 0.65 8.9 0.9 2.1 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Pkinase PF00069.20 EMC81164.1 - 2.3e-47 161.3 0.0 3.8e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81164.1 - 5e-30 104.4 0.0 1e-29 103.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 EMC81164.1 - 2.7e-12 47.1 8.4 2.7e-12 47.1 5.9 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 EMC81164.1 - 0.00039 20.2 0.0 0.0013 18.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FAM117 PF15388.1 EMC81165.1 - 8e-121 403.1 15.8 1.1e-120 402.6 10.9 1.2 1 0 0 1 1 1 1 Protein Family FAM117 CagY_I PF14585.1 EMC81165.1 - 0.31 11.0 3.9 1.1 9.1 1.1 2.7 2 0 0 2 2 2 0 CagY type 1 repeat Homeobox PF00046.24 EMC81167.1 - 5.2e-14 51.5 0.5 7.9e-14 51.0 0.4 1.2 1 0 0 1 1 1 1 Homeobox domain Ank PF00023.25 EMC81169.1 - 1.1e-12 47.0 0.1 1.7e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMC81169.1 - 5.8e-12 45.7 0.0 7.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC81169.1 - 5.7e-09 35.9 0.0 6.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC81169.1 - 1.2e-08 35.2 0.0 0.00016 22.0 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81169.1 - 4.3e-08 32.6 0.1 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat START PF01852.14 EMC81170.1 - 7.1e-12 45.0 0.0 6e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 START domain DUF4098 PF13345.1 EMC81170.1 - 2.6e-05 24.0 5.5 0.04 13.8 0.7 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4098) Fez1 PF06818.10 EMC81170.1 - 0.0018 18.3 0.0 0.2 11.6 0.0 2.2 1 1 1 2 2 2 1 Fez1 DUF3540 PF12059.3 EMC81170.1 - 0.0067 16.0 0.5 15 5.1 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3540) TPR_8 PF13181.1 EMC81170.1 - 0.017 14.8 0.1 66 3.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC81170.1 - 0.3 11.3 1.0 39 4.7 0.1 4.0 3 2 0 3 3 3 0 Tetratricopeptide repeat SapB_2 PF03489.12 EMC81174.1 - 3 7.9 27.3 1.9 8.5 0.6 5.6 6 0 0 6 6 6 0 Saposin-like type B, region 2 RhoGAP PF00620.22 EMC81175.1 - 9.4e-38 129.2 0.0 1.8e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain ArfGap PF01412.13 EMC81175.1 - 1.4e-29 102.2 0.0 5.3e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EMC81175.1 - 4.3e-25 87.9 0.1 1e-08 35.2 0.1 5.1 4 1 0 4 4 4 3 PH domain PH_11 PF15413.1 EMC81175.1 - 1.4e-10 41.3 1.5 0.021 15.0 0.0 4.9 4 1 0 4 4 4 3 Pleckstrin homology domain RA PF00788.18 EMC81175.1 - 1.3e-08 35.1 0.2 3.2e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_3 PF14593.1 EMC81175.1 - 2.4e-08 33.7 0.3 0.00055 19.7 0.1 3.5 3 0 0 3 3 3 2 PH domain PH_6 PF15406.1 EMC81175.1 - 1.1e-07 31.8 0.0 0.00024 21.1 0.0 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 EMC81175.1 - 2.6e-07 30.6 1.3 0.024 14.7 0.3 3.8 4 0 0 4 4 4 2 Pleckstrin homology domain PH_9 PF15410.1 EMC81175.1 - 0.0069 16.5 0.7 5.1 7.2 0.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EMC81175.1 - 0.027 14.3 0.0 5.3 6.9 0.0 2.7 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Thioredoxin_6 PF13848.1 EMC81175.1 - 0.037 13.8 0.1 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain PH_4 PF15404.1 EMC81175.1 - 0.044 13.3 0.4 3.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4266 PF14086.1 EMC81175.1 - 0.86 10.1 6.8 6.5 7.3 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) FEZ PF07763.8 EMC81176.1 - 1.7e-10 41.0 13.7 5.5e-10 39.3 9.5 2.0 1 1 0 1 1 1 1 FEZ-like protein Nop14 PF04147.7 EMC81176.1 - 6.8 4.4 10.9 7.4 4.3 7.6 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EMC81178.1 - 1.1e-66 224.6 0.0 1.8e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81178.1 - 8.6e-30 103.6 0.0 1.3e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC81178.1 - 1.1e-06 27.9 0.0 2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC81178.1 - 0.00051 19.8 0.2 0.45 10.2 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC81178.1 - 0.099 11.5 0.0 0.22 10.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Mob1_phocein PF03637.12 EMC81179.1 - 1.5e-75 252.6 0.8 1.8e-75 252.4 0.5 1.0 1 0 0 1 1 1 1 Mob1/phocein family APG6 PF04111.7 EMC81180.1 - 0.0016 17.5 1.6 0.0037 16.3 1.1 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 EF-hand_7 PF13499.1 EMC81180.1 - 0.0027 17.8 0.1 5 7.3 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC81180.1 - 0.0034 17.1 0.8 1.4 8.9 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain FlaC_arch PF05377.6 EMC81180.1 - 0.0063 16.3 7.5 0.0095 15.8 0.6 3.9 2 1 1 4 4 4 1 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EMC81180.1 - 0.016 15.2 2.9 0.016 15.2 2.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.9 EMC81180.1 - 0.017 14.5 0.8 0.017 14.5 0.6 3.0 1 1 1 2 2 1 0 Hepatic lectin, N-terminal domain DUF342 PF03961.8 EMC81180.1 - 0.043 12.2 2.1 0.07 11.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EF-hand_1 PF00036.27 EMC81180.1 - 0.06 12.6 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 EF hand DUF730 PF05325.6 EMC81180.1 - 0.064 13.0 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) DUF4047 PF13256.1 EMC81180.1 - 0.075 12.9 1.9 0.18 11.7 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) EF-hand_5 PF13202.1 EMC81180.1 - 0.13 11.6 0.4 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 EF hand Reo_sigmaC PF04582.7 EMC81180.1 - 0.45 9.6 7.3 0.03 13.5 0.5 2.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EMC81180.1 - 0.99 9.5 13.2 0.073 13.2 4.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HsbA PF12296.3 EMC81180.1 - 1.2 8.9 6.1 6.5 6.6 0.2 3.0 3 0 0 3 3 3 0 Hydrophobic surface binding protein A SlyX PF04102.7 EMC81180.1 - 2.7 8.4 9.8 37 4.8 0.0 4.3 3 2 1 4 4 4 0 SlyX Tropomyosin_1 PF12718.2 EMC81180.1 - 3.7 7.3 13.1 0.039 13.7 1.5 2.5 3 0 0 3 3 2 0 Tropomyosin like IncA PF04156.9 EMC81180.1 - 3.9 7.0 16.0 0.052 13.1 4.0 2.9 2 2 0 2 2 2 0 IncA protein Fer4_5 PF12801.2 EMC81181.1 - 0.1 12.3 1.4 0.14 11.9 0.9 1.2 1 0 0 1 1 1 0 4Fe-4S binding domain HLH PF00010.21 EMC81182.1 - 1.8e-12 46.7 0.7 3.3e-12 45.8 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain STIL_N PF15253.1 EMC81183.1 - 2.8e-185 615.8 0.0 6.7e-185 614.6 0.0 1.7 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus ADK PF00406.17 EMC81184.1 - 1.5e-44 151.4 0.0 2e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EMC81184.1 - 4e-09 37.3 0.0 5.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC81184.1 - 7.2e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMC81184.1 - 3.8e-07 29.6 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EMC81184.1 - 3.9e-07 30.0 0.0 6.8e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC81184.1 - 0.00014 21.0 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin FeoC PF09012.5 EMC81184.1 - 0.046 13.4 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator AAA_19 PF13245.1 EMC81184.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Fork_head PF00250.13 EMC81185.1 - 1.2e-19 70.0 0.0 1.8e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Fork head domain TraB PF01963.12 EMC81186.1 - 6e-11 42.2 0.0 6.2e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 TraB family Stap_Strp_tox_C PF02876.12 EMC81186.1 - 0.053 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain TraB PF01963.12 EMC81187.1 - 4.5e-08 32.8 0.0 3.6e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 TraB family SSF PF00474.12 EMC81188.1 - 2.9e-148 493.8 20.9 4.1e-148 493.3 14.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Peptidase_M14 PF00246.19 EMC81190.1 - 4.2e-28 98.7 0.0 5.8e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase BEN PF10523.4 EMC81191.1 - 3.6e-12 46.1 0.1 9.3e-12 44.8 0.1 1.8 1 1 0 1 1 1 1 BEN domain Peptidase_M4_C PF02868.10 EMC81191.1 - 0.0065 16.2 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Drf_FH1 PF06346.7 EMC81193.1 - 0.11 12.0 106.0 12 5.3 41.2 2.8 1 1 1 2 2 2 0 Formin Homology Region 1 NpwBP PF12622.2 EMC81194.1 - 0.00098 19.5 17.4 20 5.7 0.9 6.4 1 1 4 5 5 5 5 mRNA biogenesis factor MRP-L20 PF12824.2 EMC81194.1 - 2.5 8.0 14.0 1.2e+02 2.6 0.2 5.3 1 1 5 6 6 6 0 Mitochondrial ribosomal protein subunit L20 UBX PF00789.15 EMC81195.1 - 1.3e-20 73.2 0.1 3.7e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EMC81195.1 - 5.5e-08 32.2 0.2 1.3e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.18 EMC81195.1 - 0.0058 15.9 0.0 3.8 6.9 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin family AAA_11 PF13086.1 EMC81195.1 - 0.017 14.6 0.9 0.031 13.8 0.6 1.4 1 0 0 1 1 1 0 AAA domain Ubiquitin_2 PF14560.1 EMC81195.1 - 0.021 15.0 0.0 2.8 8.2 0.0 3.0 2 0 0 2 2 2 0 Ubiquitin-like domain BPL_N PF09825.4 EMC81195.1 - 0.16 10.7 1.3 0.24 10.1 0.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Borrelia_P83 PF05262.6 EMC81195.1 - 0.31 9.2 6.4 0.44 8.7 4.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.1 EMC81195.1 - 2 8.7 8.0 3.7 7.8 5.6 1.4 1 0 0 1 1 1 0 AAA domain Ank_5 PF13857.1 EMC81196.1 - 5e-27 93.3 9.9 1.2e-12 47.6 0.4 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC81196.1 - 1.3e-24 86.3 0.6 1.2e-16 60.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81196.1 - 1.8e-20 71.6 3.4 3.1e-06 26.7 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMC81196.1 - 2.4e-19 69.2 0.3 5.1e-09 36.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81196.1 - 2e-12 46.0 0.1 0.0015 18.5 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat DUF1843 PF08898.5 EMC81196.1 - 0.033 14.2 0.2 0.088 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) zf-RING_2 PF13639.1 EMC81197.1 - 5e-14 51.8 5.7 6.9e-14 51.4 4.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC81197.1 - 7.1e-09 35.5 6.2 1e-08 35.0 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC81197.1 - 1.2e-07 31.2 2.6 1.7e-07 30.7 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC81197.1 - 3e-06 26.7 3.5 4.7e-06 26.1 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC81197.1 - 3.6e-06 26.9 5.8 9.3e-06 25.6 4.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC81197.1 - 3.7e-06 26.5 1.9 5.3e-06 26.0 1.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC81197.1 - 0.017 14.8 1.4 0.031 14.0 0.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EMC81197.1 - 0.027 14.2 1.1 0.041 13.6 0.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EMC81197.1 - 0.068 13.0 3.9 0.13 12.1 2.7 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EMC81197.1 - 0.079 13.0 2.9 0.34 10.9 2.0 1.9 1 1 0 1 1 1 0 RING-variant domain BCDHK_Adom3 PF10436.4 EMC81197.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase FANCL_C PF11793.3 EMC81197.1 - 0.16 11.9 8.2 3.7 7.5 5.7 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 EMC81197.1 - 0.3 10.9 6.9 3.4 7.5 5.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EMC81197.1 - 0.39 10.4 3.6 0.43 10.3 0.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 EMC81197.1 - 0.49 9.9 2.9 0.78 9.3 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 EMC81197.1 - 0.6 9.8 4.1 1.4 8.6 2.8 1.7 1 1 0 1 1 1 0 PHD-finger DUF3808 PF10300.4 EMC81198.1 - 1.2e-161 538.4 2.4 1.8e-161 537.8 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 EMC81198.1 - 8.3e-10 39.0 3.1 0.00011 22.7 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC81198.1 - 1.2e-08 34.7 3.2 6.8e-07 29.1 0.9 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC81198.1 - 4.3e-06 26.8 0.2 0.026 15.1 0.1 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC81198.1 - 2.7e-05 24.3 1.4 0.37 11.3 0.7 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC81198.1 - 0.002 18.4 8.3 0.1 12.9 0.6 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC81198.1 - 0.0028 17.4 11.9 0.063 13.2 0.9 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC81198.1 - 0.042 13.4 7.1 1.4 8.6 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC81198.1 - 0.042 13.8 4.6 0.053 13.4 0.5 3.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC81198.1 - 0.051 13.3 4.2 1 9.3 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC81198.1 - 0.058 13.1 8.2 8.5 6.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMC81198.1 - 0.071 13.5 0.2 5.8 7.6 0.1 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC81198.1 - 2.5 7.8 16.7 1.6 8.4 1.1 4.6 4 1 2 6 6 6 0 TPR repeat EF-hand_4 PF12763.2 EMC81199.1 - 3.4e-41 139.2 0.2 1.9e-23 82.1 0.0 3.8 4 0 0 4 4 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EMC81199.1 - 2.2e-10 39.0 6.0 0.0041 16.3 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EMC81199.1 - 5.9e-09 35.9 0.5 0.57 10.3 0.0 4.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EMC81199.1 - 6.6e-06 25.6 5.5 0.041 13.5 0.4 3.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC81199.1 - 8e-06 25.3 4.6 1.6 8.8 0.0 4.7 4 1 1 5 5 5 2 EF-hand domain EF-hand_5 PF13202.1 EMC81199.1 - 0.00024 20.3 4.1 0.6 9.5 0.1 3.8 3 0 0 3 3 3 2 EF hand TMF_DNA_bd PF12329.3 EMC81199.1 - 0.00084 19.0 21.1 0.00084 19.0 14.7 4.8 2 1 3 5 5 4 2 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EMC81199.1 - 0.0025 17.0 16.8 0.021 14.0 4.2 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 EMC81199.1 - 0.0056 16.3 49.7 0.009 15.6 16.3 3.0 2 1 1 3 3 3 2 IncA protein LXG PF04740.7 EMC81199.1 - 0.028 14.2 23.9 0.5 10.1 0.8 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily Atg14 PF10186.4 EMC81199.1 - 0.042 12.7 31.2 0.22 10.4 11.3 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_C98 PF15499.1 EMC81199.1 - 0.2 10.9 4.8 0.31 10.2 3.3 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Laminin_II PF06009.7 EMC81199.1 - 1.7 8.4 20.2 6.4 6.5 1.9 2.8 1 1 1 2 2 2 0 Laminin Domain II IMD PF08397.6 EMC81199.1 - 2.4 7.4 21.9 20 4.4 0.9 2.4 1 1 1 2 2 2 0 IRSp53/MIM homology domain AAA_13 PF13166.1 EMC81199.1 - 2.4 6.4 36.7 0.075 11.4 19.5 2.5 2 1 0 2 2 2 0 AAA domain COG2 PF06148.6 EMC81199.1 - 5.2 6.9 23.0 2 8.3 7.1 3.1 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EMC81199.1 - 7.4 5.1 45.5 0.1 11.2 9.4 2.5 2 1 1 3 3 2 0 Spc7 kinetochore protein RTBV_P46 PF06216.6 EMC81199.1 - 9.6 4.9 11.3 0.28 9.9 0.5 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Yae1_N PF09811.4 EMC81201.1 - 4.6e-17 61.2 53.6 1.5e+04 -14.5 37.1 4.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MIP-T3 PF10243.4 EMC81202.1 - 0.00018 20.1 116.3 0.00033 19.2 80.6 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 EMC81202.1 - 3.2 5.7 88.7 3.9 5.5 61.5 1.0 1 0 0 1 1 1 0 Utp14 protein Ras PF00071.17 EMC81204.1 - 1.5e-50 170.7 0.0 1.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81204.1 - 1.1e-17 64.5 0.0 1.8e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81204.1 - 3.8e-10 39.2 0.0 5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EMC81204.1 - 0.00052 19.6 0.3 0.0075 15.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EMC81204.1 - 0.00054 19.4 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EMC81204.1 - 0.035 12.7 0.0 0.16 10.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit NADH_Oxid_Nqo15 PF11497.3 EMC81204.1 - 0.098 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 MMR_HSR1 PF01926.18 EMC81204.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase C2 PF00168.25 EMC81205.1 - 1.6e-46 156.0 0.1 2.1e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain PTEN_C2 PF10409.4 EMC81205.1 - 0.0076 15.9 0.1 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein CEP76-C2 PF15627.1 EMC81205.1 - 0.072 12.5 0.1 7.3 6.0 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain BRE1 PF08647.6 EMC81205.1 - 0.57 10.1 4.8 0.21 11.5 1.3 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AT_hook PF02178.14 EMC81206.1 - 0.99 9.3 38.1 0.089 12.5 1.1 5.2 4 0 0 4 4 4 0 AT hook motif UT PF03253.9 EMC81207.1 - 2.5e-230 762.1 67.0 7.5e-116 386.2 19.3 2.0 2 0 0 2 2 2 2 Urea transporter UCH PF00443.24 EMC81208.1 - 0.016 14.3 0.1 0.038 13.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Gp58 PF07902.6 EMC81208.1 - 5.1 5.1 1.3 9.7 4.2 0.9 1.3 1 0 0 1 1 1 0 gp58-like protein zf-C4H2 PF10146.4 EMC81210.1 - 0.86 9.5 13.0 0.14 12.1 6.4 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein RNF111_N PF15303.1 EMC81212.1 - 3.5e-81 272.6 30.3 5.9e-81 271.9 21.0 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus PLAT PF01477.18 EMC81215.1 - 5.4e-262 851.4 44.5 1.1e-23 83.7 0.2 15.0 15 0 0 15 15 15 14 PLAT/LH2 domain ATS3 PF06232.6 EMC81215.1 - 2.8e-29 101.2 0.5 0.0048 16.4 0.0 12.1 12 1 0 13 13 13 7 Embryo-specific protein 3, (ATS3) RNA_polI_A34 PF08208.6 EMC81215.1 - 0.0021 17.7 4.4 0.023 14.3 2.3 2.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_transf_29 PF00777.13 EMC81216.1 - 8.8e-78 261.1 0.0 1.1e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) CST-I PF06002.7 EMC81216.1 - 6.9e-05 22.2 0.1 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 Alpha-2,3-sialyltransferase (CST-I) RVT_1 PF00078.22 EMC81217.1 - 0.097 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PINIT PF14324.1 EMC81218.1 - 5.4e-41 140.0 0.0 9.4e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EMC81218.1 - 2.9e-21 74.7 5.2 5.8e-21 73.7 3.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMC81218.1 - 9.9e-05 21.7 1.8 0.0003 20.2 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EMC81218.1 - 0.0017 17.7 0.0 0.0045 16.4 0.0 1.7 1 0 0 1 1 1 1 SAP domain PHD PF00628.24 EMC81218.1 - 0.15 11.7 2.2 0.31 10.7 1.5 1.5 1 0 0 1 1 1 0 PHD-finger AAA PF00004.24 EMC81219.1 - 5e-38 130.2 0.0 1e-37 129.2 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC81219.1 - 4.8e-05 23.5 0.1 0.00014 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC81219.1 - 5.5e-05 22.3 0.0 9.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMC81219.1 - 0.00023 21.9 0.0 0.00052 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMC81219.1 - 0.00047 18.9 0.0 0.00074 18.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EMC81219.1 - 0.00048 20.1 0.0 0.0023 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EMC81219.1 - 0.00049 19.7 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EMC81219.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EMC81219.1 - 0.0021 17.6 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMC81219.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EMC81219.1 - 0.0023 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC81219.1 - 0.0044 16.4 0.5 0.1 12.0 0.3 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMC81219.1 - 0.0048 16.0 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMC81219.1 - 0.0051 16.9 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.1 EMC81219.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC81219.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EMC81219.1 - 0.048 12.5 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EMC81219.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EMC81219.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMC81219.1 - 0.073 12.5 0.0 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EMC81219.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Hydrolase_like PF13242.1 EMC81220.1 - 3.5e-18 65.0 0.1 1.1e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMC81220.1 - 4.1e-15 55.5 0.0 9.6e-15 54.3 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC81220.1 - 4.3e-08 33.5 0.0 6e-07 29.8 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC81220.1 - 6.5e-05 23.4 0.1 0.0014 19.1 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4032 PF13224.1 EMC81220.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) Ski_Sno PF02437.12 EMC81221.1 - 8.2e-40 134.9 0.2 1.1e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.5 EMC81221.1 - 2.8e-31 107.4 3.8 2.8e-31 107.4 2.7 1.8 2 0 0 2 2 2 1 c-SKI Smad4 binding domain MH2 PF03166.9 EMC81222.1 - 1.1e-77 260.0 0.0 1.5e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 EMC81222.1 - 1.6e-43 146.9 2.0 2.9e-43 146.0 1.4 1.4 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 EMC81222.1 - 1.3e-06 28.1 0.1 8.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Interferon-regulatory factor 3 BTB PF00651.26 EMC81223.1 - 1.7e-33 114.8 1.5 1.2e-32 112.2 0.4 2.2 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC81223.1 - 5.1e-22 77.0 30.9 8.3e-08 32.1 0.7 5.2 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC81223.1 - 2.7e-12 46.0 23.4 0.001 19.2 2.5 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC81223.1 - 6.4e-12 45.0 35.8 0.0001 22.3 0.9 5.3 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMC81223.1 - 0.0032 17.5 23.3 0.036 14.2 1.1 5.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC81223.1 - 0.0074 16.4 20.1 0.12 12.6 0.2 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 EMC81223.1 - 0.015 15.2 1.2 1.4 9.0 0.0 3.6 3 0 0 3 3 3 0 zinc-finger CDC45 PF02724.9 EMC81223.1 - 0.023 12.7 4.4 0.028 12.4 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 EMC81223.1 - 0.066 13.0 6.2 0.13 12.0 4.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal zf-Di19 PF05605.7 EMC81223.1 - 0.079 13.1 14.3 2.1 8.5 4.6 3.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Mpp10 PF04006.7 EMC81223.1 - 0.096 11.0 17.8 0.15 10.4 12.3 1.2 1 0 0 1 1 1 0 Mpp10 protein Daxx PF03344.10 EMC81223.1 - 0.11 10.9 18.2 0.15 10.4 12.6 1.1 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 EMC81223.1 - 0.15 10.8 7.2 0.27 10.0 5.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 EMC81223.1 - 0.18 10.5 16.3 0.36 9.4 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EMC81223.1 - 0.18 11.4 11.1 0.31 10.6 7.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region GAGA PF09237.6 EMC81223.1 - 0.23 11.0 6.5 0.45 10.1 0.1 3.5 1 1 3 4 4 4 0 GAGA factor CobT PF06213.7 EMC81223.1 - 0.25 10.4 16.1 0.36 9.9 11.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VID27 PF08553.5 EMC81223.1 - 0.38 8.9 7.0 0.51 8.4 4.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAM176 PF14851.1 EMC81223.1 - 0.46 10.1 8.2 0.93 9.1 5.7 1.5 1 0 0 1 1 1 0 FAM176 family zf-C2H2_2 PF12756.2 EMC81223.1 - 1.1 9.3 19.0 5.2 7.2 0.7 4.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Sporozoite_P67 PF05642.6 EMC81223.1 - 2.3 5.9 6.9 3.1 5.5 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.11 EMC81223.1 - 2.4 7.0 10.5 4.2 6.2 7.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.6 EMC81223.1 - 2.8 7.1 18.8 4.7 6.4 13.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Zn_Tnp_IS1595 PF12760.2 EMC81223.1 - 2.8 7.7 10.3 3.9 7.3 1.8 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Nop14 PF04147.7 EMC81223.1 - 3.1 5.6 19.4 4.6 5.0 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 EMC81223.1 - 4.6 6.5 11.2 6.8 5.9 7.7 1.2 1 0 0 1 1 1 0 Vta1 like DUF2722 PF10846.3 EMC81223.1 - 4.8 6.1 7.8 7.1 5.5 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Myc_N PF01056.13 EMC81223.1 - 5.3 6.1 12.3 10 5.1 8.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Fmp27 PF10344.4 EMC81224.1 - 0.13 9.8 1.4 0.2 9.3 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Pox_A32 PF04665.7 EMC81224.1 - 0.15 11.3 0.3 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein SRP-alpha_N PF04086.8 EMC81224.1 - 2.3 7.5 28.2 3 7.1 19.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal VIT1 PF01988.14 EMC81224.1 - 6.1 6.2 7.8 9.2 5.6 5.4 1.3 1 0 0 1 1 1 0 VIT family OATP PF03137.15 EMC81225.1 - 1.4e-75 254.3 10.7 2e-75 253.9 7.4 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.10 EMC81225.1 - 9.1e-07 28.7 3.5 3.5e-06 26.8 2.5 2.1 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain MFS_1 PF07690.11 EMC81225.1 - 2.1e-06 26.6 14.4 0.0034 16.1 5.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_1 PF00050.16 EMC81225.1 - 0.0014 18.6 5.6 0.0026 17.7 3.3 1.9 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain EMP70 PF02990.11 EMC81225.1 - 0.15 10.5 3.0 3 6.2 2.7 2.1 2 0 0 2 2 2 0 Endomembrane protein 70 DUF1443 PF07280.6 EMC81226.1 - 0.022 14.3 0.3 0.022 14.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1443) PGM_PMM_I PF02878.11 EMC81227.1 - 9.9e-29 99.5 0.0 2.6e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMC81227.1 - 2e-25 89.1 0.1 1.8e-24 86.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EMC81227.1 - 2.8e-13 49.8 0.3 6.4e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EMC81227.1 - 4.1e-08 33.1 0.0 2.6e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NARG2_C PF10505.4 EMC81229.1 - 3e-64 216.2 0.1 6e-64 215.2 0.1 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Annexin PF00191.15 EMC81230.1 - 2.1e-86 283.7 8.8 2.9e-27 94.3 0.4 4.1 4 0 0 4 4 4 4 Annexin Fork_head PF00250.13 EMC81231.1 - 3.3e-43 145.6 0.1 4.6e-43 145.1 0.1 1.2 1 0 0 1 1 1 1 Fork head domain HNF_C PF09354.5 EMC81231.1 - 1.8 9.7 5.1 0.37 11.9 0.4 2.3 2 1 0 2 2 2 0 HNF3 C-terminal domain BNIP2 PF12496.3 EMC81232.1 - 6.2e-40 136.3 1.9 9.1e-40 135.7 1.3 1.2 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 EMC81232.1 - 4.9e-29 101.1 0.1 7.2e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EMC81232.1 - 1e-08 34.8 0.1 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2810 PF10928.3 EMC81232.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) TFIIA_gamma_N PF02268.11 EMC81233.1 - 2.1e-24 84.8 0.5 2.9e-24 84.3 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EMC81233.1 - 5.7e-24 83.6 2.6 8.1e-24 83.1 1.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Branch PF02485.16 EMC81234.1 - 1.7e-60 204.2 0.0 2e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme OTU PF02338.14 EMC81235.1 - 8.6e-29 100.5 0.0 2.6e-28 99.0 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.1 EMC81235.1 - 4.2e-05 22.9 0.0 7.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain zf-A20 PF01754.11 EMC81235.1 - 0.00015 21.2 8.3 0.00027 20.4 5.8 1.5 1 0 0 1 1 1 1 A20-like zinc finger zf-H2C2_2 PF13465.1 EMC81236.1 - 4.4e-15 55.1 28.5 5.6e-08 32.6 0.7 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC81236.1 - 2.8e-14 52.5 20.5 0.00014 22.0 0.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81236.1 - 1.7e-12 46.6 17.8 0.00023 21.2 0.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMC81236.1 - 0.0018 18.3 9.8 0.46 10.7 0.3 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.10 EMC81236.1 - 0.029 14.1 11.9 0.11 12.3 2.2 2.9 2 1 1 3 3 3 0 BED zinc finger zf-TRAF PF02176.13 EMC81236.1 - 0.049 14.0 2.7 0.049 14.0 1.9 2.8 2 1 1 3 3 3 0 TRAF-type zinc finger RPAP2_Rtr1 PF04181.8 EMC81236.1 - 0.39 10.8 4.5 21 5.3 3.1 2.5 1 1 0 1 1 1 0 Rtr1/RPAP2 family IBR PF01485.16 EMC81236.1 - 0.83 9.5 5.8 5.9 6.8 4.0 2.1 1 1 0 1 1 1 0 IBR domain zf-Di19 PF05605.7 EMC81236.1 - 2.1 8.5 12.0 0.25 11.4 1.5 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ion_trans PF00520.26 EMC81237.1 - 6.3e-10 38.6 14.5 6.3e-10 38.6 10.1 2.4 2 1 0 2 2 2 1 Ion transport protein Myotub-related PF06602.9 EMC81238.1 - 7.6e-90 301.2 3.5 7.8e-67 225.5 1.8 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.3 EMC81238.1 - 1.2e-37 128.9 0.1 2e-37 128.2 0.1 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein Rbsn PF11464.3 EMC81238.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Rabenosyn Rab binding domain VRR_NUC PF08774.6 EMC81239.1 - 2.1e-21 75.7 0.0 4.4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Mpp10 PF04006.7 EMC81240.1 - 4.3e-158 527.3 86.7 5.7e-158 526.9 60.1 1.1 1 0 0 1 1 1 1 Mpp10 protein Glyoxalase_4 PF13669.1 EMC81241.1 - 2.1e-23 82.3 0.0 2.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMC81241.1 - 3.8e-12 46.7 0.0 4.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EMC81241.1 - 7.2e-12 45.3 0.0 8.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMC81241.1 - 2.9e-09 37.0 0.0 3.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain PID PF00640.18 EMC81242.1 - 2.5e-50 170.0 2.5 2.5e-50 170.0 1.7 2.4 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 EMC81242.1 - 8.5e-33 112.3 6.5 2.7e-16 59.5 0.7 2.8 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC81242.1 - 3.3e-06 26.8 0.0 0.00053 19.8 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Phage_CP76 PF06892.6 EMC81242.1 - 0.044 13.1 0.9 0.41 9.9 0.1 2.7 2 1 0 2 2 2 0 Phage regulatory protein CII (CP76) Tricorn_PDZ PF14685.1 EMC81242.1 - 0.092 12.5 0.3 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain CD20 PF04103.10 EMC81243.1 - 2.1e-07 30.9 10.8 4.1e-07 30.0 7.5 1.5 1 0 0 1 1 1 1 CD20-like family PDZ PF00595.19 EMC81244.1 - 8.9e-50 166.7 7.2 4.6e-16 58.7 0.1 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) ZU5 PF00791.15 EMC81244.1 - 9.4e-36 121.6 0.0 2.5e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 ZU5 domain PDZ_2 PF13180.1 EMC81244.1 - 6.3e-18 64.4 4.0 7.9e-06 25.6 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 EMC81244.1 - 1.6e-11 44.0 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 EMC81244.1 - 3.6e-11 42.3 0.1 9.8e-11 40.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC81244.1 - 0.0016 17.8 0.1 0.014 14.7 0.0 2.6 2 0 0 2 2 2 1 SH3 domain DUF104 PF01954.11 EMC81244.1 - 0.12 12.4 2.1 2.2 8.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF104 tRNA-synt_2b PF00587.20 EMC81245.1 - 6.9e-45 152.7 0.2 1.2e-44 151.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMC81245.1 - 7.2e-21 73.9 0.1 1.8e-20 72.6 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EMC81245.1 - 9e-14 51.0 0.0 2.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EMC81245.1 - 6.7e-13 48.2 0.0 1.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain TM2 PF05154.11 EMC81246.1 - 1.8e-14 53.6 8.3 2.6e-14 53.1 5.8 1.3 1 0 0 1 1 1 1 TM2 domain A_deaminase PF00962.17 EMC81247.1 - 6e-45 153.5 0.0 6.9e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase La PF05383.12 EMC81248.1 - 2.1e-22 78.6 0.2 4.4e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 La domain SUZ-C PF12901.2 EMC81248.1 - 4.2e-09 35.8 0.3 8.8e-09 34.7 0.2 1.5 1 0 0 1 1 1 1 SUZ-C motif LRR_4 PF12799.2 EMC81249.1 - 4.6e-27 93.1 34.6 6.1e-09 35.2 3.6 5.7 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EMC81249.1 - 2.6e-18 66.1 11.9 3.8e-11 42.8 1.3 4.0 2 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.1 EMC81249.1 - 6.2e-15 54.7 43.2 1.9e-07 30.6 7.1 6.1 3 1 4 8 8 8 5 Leucine rich repeat LRR_1 PF00560.28 EMC81249.1 - 4.8e-06 25.8 39.2 0.32 11.1 0.2 8.4 6 1 1 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.1 EMC81249.1 - 0.00029 20.5 26.8 1.4 9.1 0.4 8.1 4 1 4 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 EMC81249.1 - 0.06 13.5 24.6 2.4 8.7 0.1 8.4 5 2 1 6 6 6 0 Leucine rich repeat DUF2322 PF10084.4 EMC81249.1 - 0.26 11.0 3.3 2.3 8.0 0.1 3.4 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) Neur_chan_LBD PF02931.18 EMC81250.1 - 4e-71 238.6 1.0 5.3e-71 238.2 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC81250.1 - 1.3e-62 211.7 0.0 1.6e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region AHS1 PF02682.11 EMC81251.1 - 0.28 10.6 5.9 3.9 6.8 1.4 2.6 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 Baculo_PEP_C PF04513.7 EMC81251.1 - 1.3 8.8 21.3 1.2 8.9 0.4 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_C_2 PF01322.15 EMC81251.1 - 3.6 8.1 8.7 9.4 6.8 4.3 2.6 2 1 0 2 2 2 0 Cytochrome C' Myosin_head PF00063.16 EMC81252.1 - 2.1e-239 796.1 3.2 3.7e-239 795.3 2.2 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EMC81252.1 - 1.3e-63 213.9 0.7 2.3e-63 213.1 0.5 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EMC81252.1 - 2.9e-17 61.7 0.3 1.1e-16 59.9 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC81252.1 - 2.4e-16 59.0 0.1 6.1e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC81252.1 - 5.9e-12 44.8 0.0 1.6e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EMC81252.1 - 0.0016 18.5 0.0 0.0085 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 EMC81252.1 - 0.0087 15.6 3.1 0.023 14.2 2.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_18 PF13238.1 EMC81252.1 - 0.012 15.9 0.6 0.22 11.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMC81252.1 - 0.054 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EMC81252.1 - 0.087 13.1 0.1 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EMC81252.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EMC81252.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Cyclin_N PF00134.18 EMC81253.1 - 5.7e-41 139.0 0.8 1.3e-40 137.8 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC81253.1 - 1.4e-31 108.8 1.5 3.3e-31 107.6 1.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain RNF111_N PF15303.1 EMC81254.1 - 1.2e-109 365.9 22.8 1.2e-109 365.9 15.8 2.6 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus zf-RING_2 PF13639.1 EMC81254.1 - 7.3e-15 54.5 6.2 7.2e-15 54.5 4.3 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC81254.1 - 5.3e-08 32.4 3.9 5.3e-08 32.4 2.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC81254.1 - 2e-07 30.8 6.7 2e-07 30.8 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC81254.1 - 6.8e-07 29.3 5.2 6.8e-07 29.3 3.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC81254.1 - 1.5e-06 27.7 5.9 1.5e-06 27.7 4.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC81254.1 - 4.9e-06 26.1 3.9 4.9e-06 26.1 2.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC81254.1 - 0.055 13.3 5.8 0.11 12.2 2.7 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.17 EMC81255.1 - 1.2e-11 44.0 0.0 2.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC81255.1 - 6.2e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC81255.1 - 1.8e-05 24.4 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF544 PF04424.8 EMC81256.1 - 3.1e-45 152.8 1.4 3.5e-45 152.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF544) Rad33 PF08730.5 EMC81256.1 - 0.13 11.7 1.9 0.13 11.7 0.3 1.7 2 0 0 2 2 2 0 Rad33 CCDC50_N PF15295.1 EMC81256.1 - 0.81 9.6 13.0 2.1 8.2 9.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Ribosomal_60s PF00428.14 EMC81256.1 - 4.8 7.6 5.8 11 6.4 4.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Lipase PF00151.14 EMC81257.1 - 1.9e-109 365.8 0.0 2.4e-109 365.5 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 EMC81257.1 - 9.5e-21 74.2 1.2 2.2e-20 73.1 0.8 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 EMC81257.1 - 1.4e-05 25.1 0.1 1.7e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MIP PF00230.15 EMC81258.1 - 7.2e-51 172.8 13.5 8.8e-51 172.5 9.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4401 PF14351.1 EMC81258.1 - 0.018 14.0 11.4 0.079 11.9 7.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) LtrA PF06772.6 EMC81258.1 - 0.049 12.5 0.7 0.23 10.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) Aldedh PF00171.17 EMC81259.1 - 6.3e-183 608.3 0.0 7e-183 608.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC81259.1 - 0.0073 15.0 0.1 0.11 11.1 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMC81259.1 - 0.011 14.9 0.1 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ldh_2 PF02615.9 EMC81259.1 - 0.11 11.2 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase GCOM2 PF15328.1 EMC81260.1 - 3.9e-72 242.6 41.9 3.9e-72 242.6 29.0 2.0 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 SlyX PF04102.7 EMC81260.1 - 0.022 15.1 3.0 0.022 15.1 2.1 6.5 3 2 3 7 7 7 0 SlyX Reo_sigmaC PF04582.7 EMC81260.1 - 0.19 10.8 15.1 0.48 9.5 4.0 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein HMA PF00403.21 EMC81260.1 - 0.25 11.5 0.0 0.25 11.5 0.0 3.4 4 0 0 4 4 4 0 Heavy-metal-associated domain DUF869 PF05911.6 EMC81260.1 - 0.43 8.7 57.0 0.57 8.3 14.1 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Myosin_tail_1 PF01576.14 EMC81261.1 - 1.1e-44 152.5 190.1 4.7e-29 100.7 32.2 4.0 1 1 2 3 3 3 3 Myosin tail ERM PF00769.14 EMC81261.1 - 0.0033 16.9 40.5 0.0033 16.9 28.0 6.8 3 2 3 6 6 6 2 Ezrin/radixin/moesin family Filament PF00038.16 EMC81261.1 - 0.037 13.4 163.1 0.26 10.7 38.5 6.4 1 1 3 5 5 5 0 Intermediate filament protein Reo_sigmaC PF04582.7 EMC81261.1 - 0.16 11.1 49.9 0.052 12.7 2.2 6.4 1 1 5 6 6 6 0 Reovirus sigma C capsid protein HLH PF00010.21 EMC81262.1 - 3.2e-11 42.7 0.9 3.6e-10 39.3 0.9 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.9 EMC81262.1 - 1.5 6.7 7.9 2 6.3 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EMC81263.1 - 0.0078 14.5 25.9 0.0096 14.2 17.9 1.1 1 0 0 1 1 1 1 Transmembrane protein CCDC155 PF14662.1 EMC81263.1 - 0.27 10.7 33.7 0.51 9.9 17.5 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 GAS PF13851.1 EMC81263.1 - 0.65 9.1 37.6 0.068 12.3 14.2 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FUSC PF04632.7 EMC81263.1 - 1.3 7.3 3.7 1.6 7.0 2.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.3 EMC81263.1 - 1.4 6.1 28.3 2.2 5.5 19.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS-augmin3 PF14932.1 EMC81263.1 - 2 7.5 30.9 12 4.9 11.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 THOC7 PF05615.8 EMC81263.1 - 2.1 8.6 27.7 1.2 9.4 11.6 2.6 1 1 2 3 3 3 0 Tho complex subunit 7 PLRV_ORF5 PF01690.12 EMC81263.1 - 2.4 7.1 10.9 2.7 7.0 7.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Peptidase_C10 PF01640.12 EMC81263.1 - 2.5 7.8 5.5 4 7.1 3.8 1.3 1 0 0 1 1 1 0 Peptidase C10 family CheY-binding PF09078.6 EMC81263.1 - 2.6 8.0 8.2 18 5.4 0.2 3.3 3 0 0 3 3 3 0 CheY binding HAUS6_N PF14661.1 EMC81263.1 - 4.5 6.5 24.6 4.1 6.6 7.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_2 PF07716.10 EMC81263.1 - 7.2 6.5 29.2 0.25 11.1 2.2 4.6 4 1 0 4 4 4 0 Basic region leucine zipper Mnd1 PF03962.10 EMC81263.1 - 8.8 5.9 31.4 2.8 7.5 14.0 2.3 1 1 1 2 2 2 0 Mnd1 family HECT PF00632.20 EMC81265.1 - 5.3e-95 318.2 0.1 7.5e-95 317.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMC81265.1 - 3e-44 148.4 27.0 3e-13 49.3 0.4 5.3 5 0 0 5 5 5 4 WW domain C2 PF00168.25 EMC81265.1 - 1.1e-21 76.4 0.1 2.5e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 C2 domain fn3 PF00041.16 EMC81266.1 - 1.6e-62 207.5 4.0 1.4e-11 44.3 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 EMC81266.1 - 1e-56 188.7 0.0 2e-15 56.3 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC81266.1 - 7.7e-35 118.8 0.1 1.9e-08 34.3 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 EMC81266.1 - 3.1e-30 104.4 0.3 9.6e-08 32.4 0.0 5.9 6 0 0 6 6 5 4 Immunoglobulin domain ig PF00047.20 EMC81266.1 - 4e-24 84.5 0.0 0.00028 20.9 0.0 5.4 5 1 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 EMC81266.1 - 5.1e-18 65.0 0.1 0.0025 17.6 0.0 6.1 4 3 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC81266.1 - 1.2e-10 41.1 0.5 0.028 14.3 0.0 4.6 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC81266.1 - 1.9e-07 29.7 0.1 0.016 13.4 0.0 3.5 2 1 1 3 3 3 3 Alphaherpesvirus glycoprotein E C1-set PF07654.10 EMC81266.1 - 0.00085 19.2 0.7 0.46 10.5 0.0 4.6 5 1 0 5 5 5 1 Immunoglobulin C1-set domain Adeno_E3_CR2 PF02439.10 EMC81266.1 - 0.013 15.0 3.9 0.028 13.9 2.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 EMC81266.1 - 0.048 13.3 0.2 0.33 10.6 0.3 2.2 2 0 0 2 2 2 0 Syndecan domain STE2 PF02116.10 EMC81266.1 - 0.16 10.9 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR RasGAP PF00616.14 EMC81267.1 - 1.6e-50 171.5 0.0 1.6e-50 171.5 0.0 2.5 2 1 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EMC81267.1 - 2.7e-42 143.8 15.7 4.7e-41 139.7 9.6 3.9 4 0 0 4 4 4 2 RasGAP C-terminus IQ PF00612.22 EMC81267.1 - 8.5e-19 65.3 20.1 1.1e-05 24.6 0.4 5.2 5 0 0 5 5 5 4 IQ calmodulin-binding motif CH PF00307.26 EMC81267.1 - 1.1e-14 54.3 0.0 6.4e-14 51.8 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain WW PF00397.21 EMC81267.1 - 0.077 12.8 4.9 0.15 11.9 3.4 1.5 1 0 0 1 1 1 0 WW domain Spc97_Spc98 PF04130.8 EMC81268.1 - 8.4e-108 361.0 10.0 1.1e-107 360.6 6.9 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family 53-BP1_Tudor PF09038.5 EMC81269.1 - 2.9e-76 253.0 0.2 5.5e-76 252.2 0.1 1.5 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor BRCT PF00533.21 EMC81269.1 - 0.001 19.1 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.1 EMC81269.1 - 0.0021 17.8 0.2 0.01 15.6 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4537) His_Phos_2 PF00328.17 EMC81270.1 - 4.3e-103 345.2 0.0 6.4e-103 344.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EMC81270.1 - 0.0042 17.1 0.1 0.016 15.2 0.0 2.1 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) RimK PF08443.6 EMC81270.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-gua_Ptrans PF00217.14 EMC81271.1 - 4.1e-86 288.2 0.0 5e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 EMC81271.1 - 4.5e-35 119.6 0.0 6.9e-35 119.0 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Thioredoxin PF00085.15 EMC81272.1 - 7.1e-46 154.1 0.0 3.8e-32 110.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EMC81272.1 - 1.8e-41 141.9 0.5 2.3e-36 125.3 0.6 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EMC81272.1 - 3.5e-10 40.0 0.2 2.1e-06 27.8 0.1 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC81272.1 - 6e-06 26.2 0.2 0.00092 19.2 0.0 3.6 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EMC81272.1 - 7.6e-05 22.6 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Calsequestrin PF01216.12 EMC81272.1 - 0.00042 19.1 0.2 0.0022 16.8 0.0 2.0 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_4 PF13462.1 EMC81272.1 - 0.0019 18.2 0.1 0.16 11.9 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin AhpC-TSA PF00578.16 EMC81272.1 - 0.028 14.1 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Ras PF00071.17 EMC81273.1 - 5.1e-21 74.7 0.1 5.5e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81273.1 - 7.2e-10 39.4 0.0 7.8e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC81273.1 - 0.00027 20.8 0.0 0.00029 20.7 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EMC81273.1 - 0.00036 19.8 0.0 0.00038 19.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC81273.1 - 0.00055 19.1 0.0 0.0006 19.0 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EMC81273.1 - 0.0041 16.5 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain VirE PF05272.6 EMC81273.1 - 0.011 15.2 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E AAA_16 PF13191.1 EMC81273.1 - 0.012 15.6 0.4 0.039 13.9 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 EMC81273.1 - 0.013 14.4 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) eIF-5a PF01287.15 EMC81273.1 - 0.029 14.2 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold AAA_14 PF13173.1 EMC81273.1 - 0.06 13.2 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EMC81273.1 - 0.066 13.0 0.0 0.092 12.5 0.0 1.3 1 1 0 1 1 1 0 Dynamin family DUF258 PF03193.11 EMC81273.1 - 0.068 12.3 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 EMC81273.1 - 0.075 12.0 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 EMC81273.1 - 0.082 13.0 0.0 0.088 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMC81273.1 - 0.085 12.1 0.0 0.097 11.9 0.0 1.0 1 0 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 EMC81273.1 - 0.089 12.4 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 EMC81273.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EMC81273.1 - 0.11 12.1 0.1 0.11 12.1 0.0 1.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Serinc PF03348.10 EMC81274.1 - 2.1e-92 310.1 15.5 2e-89 300.3 7.4 2.0 2 0 0 2 2 2 2 Serine incorporator (Serinc) Prp19_bind PF06991.6 EMC81276.1 - 2.1e-129 430.7 37.6 2.1e-129 430.7 26.1 2.2 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Peptidase_S8 PF00082.17 EMC81277.1 - 2.9e-60 203.8 6.0 4.6e-60 203.1 4.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EMC81277.1 - 8.9e-30 102.3 0.0 1.7e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain VSP PF03302.8 EMC81277.1 - 0.017 13.7 10.4 0.28 9.7 0.5 2.4 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF357 PF04010.8 EMC81277.1 - 0.061 13.0 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) GF_recep_IV PF14843.1 EMC81277.1 - 0.6 9.7 21.7 0.17 11.5 10.8 2.6 2 1 0 2 2 2 0 Growth factor receptor domain IV RCC1 PF00415.13 EMC81278.1 - 1.7e-08 34.5 0.0 1.9e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat Sec1 PF00995.18 EMC81279.1 - 1.3e-95 321.1 0.0 1.7e-95 320.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family TTL PF03133.10 EMC81280.1 - 5.2e-87 291.4 0.2 9.6e-87 290.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMC81280.1 - 8.4e-07 28.0 0.1 0.00018 20.4 0.0 3.2 2 2 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 EMC81280.1 - 0.0018 18.1 0.0 0.0091 15.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EMC81280.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMC81280.1 - 0.087 12.2 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus EF-hand_1 PF00036.27 EMC81281.1 - 3.7e-12 44.5 8.3 3e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EMC81281.1 - 1.5e-11 43.1 4.8 6.7e-05 22.4 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 EMC81281.1 - 5.8e-11 42.3 8.5 1.4e-10 41.1 1.9 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC81281.1 - 2.3e-10 39.3 3.6 9.8e-06 24.6 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMC81281.1 - 5.9e-08 32.2 10.0 0.0005 19.6 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC81281.1 - 3.8e-06 26.9 0.4 5.2e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC81281.1 - 0.0014 18.3 4.5 0.077 12.7 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC81281.1 - 0.034 14.0 0.5 0.6 10.0 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain Gal4_dimer PF03902.8 EMC81281.1 - 0.054 13.4 2.8 0.068 13.1 0.3 2.1 1 1 1 2 2 2 0 Gal4-like dimerisation domain EF-hand_10 PF14788.1 EMC81281.1 - 0.56 9.9 3.3 4.8 6.9 0.3 2.7 2 1 0 2 2 2 0 EF hand Iso_dh PF00180.15 EMC81282.1 - 1.1e-72 244.8 0.0 2.6e-72 243.6 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Clat_adaptor_s PF01217.15 EMC81283.1 - 9.6e-41 138.8 3.2 1.2e-40 138.5 2.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M1 PF01433.15 EMC81284.1 - 1.2e-59 202.3 0.2 1.6e-59 201.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 EMP24_GP25L PF01105.19 EMC81285.1 - 3.2e-29 101.9 0.4 3.5e-29 101.8 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GOLD_2 PF13897.1 EMC81285.1 - 0.0051 17.0 0.2 0.0089 16.2 0.2 1.4 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Ank_2 PF12796.2 EMC81286.1 - 1.3e-37 127.9 5.5 4.7e-19 68.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81286.1 - 2.1e-19 68.2 1.5 9.1e-07 28.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EMC81286.1 - 4.7e-17 61.9 0.5 4.5e-06 27.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81286.1 - 1e-14 53.1 0.4 0.00013 21.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC81286.1 - 2.3e-13 49.9 2.3 7.2e-08 32.4 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) FMN_dh PF01070.13 EMC81286.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NAD_binding_10 PF13460.1 EMC81286.1 - 0.093 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Peptidase_C1 PF00112.18 EMC81287.1 - 2.2e-78 263.1 0.2 2.5e-78 262.9 0.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EMC81287.1 - 8.7e-05 21.2 0.3 0.017 13.7 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.7 EMC81287.1 - 0.13 12.5 0.4 0.72 10.1 0.1 2.1 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) WD40 PF00400.27 EMC81288.1 - 3.3e-08 33.1 1.3 2.5e-05 23.9 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat gpW PF02831.10 EMC81288.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 gpW NIF PF03031.13 EMC81290.1 - 1.7e-54 183.7 2.2 2e-54 183.5 0.8 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF59 PF01883.14 EMC81291.1 - 2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 MRG PF05712.8 EMC81292.1 - 4.8e-43 146.3 0.1 7.9e-43 145.6 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EMC81292.1 - 6.3e-15 54.6 0.4 1.8e-14 53.1 0.3 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pol_alpha_B_N PF08418.5 EMC81292.1 - 0.072 12.6 1.5 0.09 12.3 1.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ank_2 PF12796.2 EMC81293.1 - 4.2e-43 145.5 9.6 3.4e-15 56.1 0.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81293.1 - 2.3e-33 112.3 7.5 4e-07 29.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EMC81293.1 - 1.9e-32 111.0 2.8 7.7e-10 39.0 0.3 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC81293.1 - 8e-30 102.1 7.6 1e-07 31.9 0.0 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81293.1 - 6e-23 78.6 1.1 0.0015 18.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Myosin_tail_1 PF01576.14 EMC81293.1 - 0.00019 19.3 22.7 0.00019 19.3 15.7 6.0 2 1 3 5 5 4 2 Myosin tail Seryl_tRNA_N PF02403.17 EMC81293.1 - 0.0027 17.7 9.3 0.0027 17.7 6.5 13.9 2 2 14 16 16 15 1 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.1 EMC81293.1 - 0.0031 17.4 13.5 0.0031 17.4 9.4 13.4 4 2 10 16 16 14 2 FlxA-like protein Reo_sigmaC PF04582.7 EMC81293.1 - 0.027 13.6 57.1 0.11 11.6 0.2 8.5 3 2 4 9 9 9 0 Reovirus sigma C capsid protein Filament PF00038.16 EMC81293.1 - 0.23 10.9 170.9 0.21 11.0 14.3 7.8 2 1 4 6 6 6 0 Intermediate filament protein AAA_13 PF13166.1 EMC81293.1 - 0.69 8.2 155.1 0.081 11.3 12.9 7.4 2 1 6 8 8 8 0 AAA domain IncA PF04156.9 EMC81293.1 - 1.5 8.3 203.0 0.013 15.1 4.5 11.2 2 1 8 11 11 11 0 IncA protein TLE_N PF03920.10 EMC81294.1 - 1.2e-35 122.2 8.3 1.7e-35 121.7 5.7 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 EMC81294.1 - 2.9e-25 87.1 16.5 1.5e-08 34.2 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMC81294.1 - 0.053 11.8 0.0 1.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribosomal_S18 PF01084.15 EMC81294.1 - 0.24 11.2 0.5 0.41 10.5 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S18 DUF4557 PF15101.1 EMC81294.1 - 4.7 6.9 6.8 4.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) HlyIII PF03006.15 EMC81296.1 - 1.6e-32 112.7 14.3 2.3e-32 112.2 9.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related Kinesin PF00225.18 EMC81297.1 - 1e-100 336.7 0.8 2.7e-100 335.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain ADIP PF11559.3 EMC81297.1 - 0.00052 19.9 11.0 0.00052 19.9 7.6 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EMC81297.1 - 0.0022 17.7 16.8 0.0064 16.2 11.6 1.9 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EMC81297.1 - 0.026 14.4 9.4 0.075 12.9 6.5 1.8 1 0 0 1 1 1 0 FlxA-like protein HrpB7 PF09486.5 EMC81297.1 - 0.074 12.9 6.6 0.61 10.0 0.1 2.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) XhlA PF10779.4 EMC81297.1 - 0.12 12.2 7.3 0.25 11.2 4.6 1.9 1 1 0 1 1 1 0 Haemolysin XhlA ORF6C PF10552.4 EMC81297.1 - 0.17 11.5 7.6 0.11 12.1 3.4 2.1 2 0 0 2 2 2 0 ORF6C domain IncA PF04156.9 EMC81297.1 - 6.6 6.2 18.2 17 4.9 12.6 1.7 1 1 0 1 1 1 0 IncA protein C5-epim_C PF06662.8 EMC81298.1 - 2.4e-77 258.4 0.1 3.9e-77 257.8 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus EspG PF06872.6 EMC81298.1 - 0.044 12.1 0.0 0.19 10.0 0.0 1.8 2 0 0 2 2 2 0 EspG protein NAD_binding_6 PF08030.7 EMC81299.1 - 2e-29 102.5 0.0 3.7e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMC81299.1 - 4.1e-21 74.8 0.0 7.9e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain EF-hand_6 PF13405.1 EMC81299.1 - 1e-19 68.5 0.1 3.8e-06 26.3 0.1 5.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 EMC81299.1 - 4.6e-19 66.1 0.4 2.9e-06 26.1 0.0 5.4 5 0 0 5 5 5 3 EF hand Ferric_reduct PF01794.14 EMC81299.1 - 1.4e-16 60.7 4.3 1.4e-16 60.7 3.0 2.1 2 1 0 2 2 1 1 Ferric reductase like transmembrane component EF-hand_5 PF13202.1 EMC81299.1 - 6.7e-14 50.5 7.4 3.3e-05 23.0 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EMC81299.1 - 9.5e-14 51.2 0.2 3.6e-05 23.8 0.0 3.1 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC81299.1 - 1.5e-09 37.2 0.6 0.0011 18.5 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain pair FAD_binding_6 PF00970.19 EMC81299.1 - 0.00077 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMC81299.1 - 0.0037 17.8 0.1 0.29 11.7 0.0 2.6 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain IBR PF01485.16 EMC81299.1 - 0.017 14.9 1.3 0.064 13.1 0.9 2.0 1 1 0 1 1 1 0 IBR domain LRR_4 PF12799.2 EMC81301.1 - 1.8e-13 49.7 18.7 3e-09 36.3 4.3 3.1 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC81301.1 - 5.2e-13 48.5 15.2 1.3e-08 34.4 3.2 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 EMC81301.1 - 3.4e-12 46.2 0.3 4.7e-12 45.8 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EMC81301.1 - 1.2e-07 31.0 12.9 6.4e-05 22.6 0.2 4.2 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.28 EMC81301.1 - 7.1e-07 28.4 6.6 0.018 14.9 0.1 4.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC81301.1 - 1.4e-06 27.5 10.7 0.16 12.2 0.1 4.9 5 0 0 5 5 5 3 Leucine rich repeat WD40 PF00400.27 EMC81302.1 - 2.3e-25 87.4 2.8 2.2e-08 33.6 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 EMC81302.1 - 4.1e-09 35.9 0.1 7.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Integrin_alpha2 PF08441.7 EMC81304.1 - 5.1e-75 253.0 0.1 7.1e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 EMC81304.1 - 2.3e-08 33.4 1.5 0.00014 21.4 0.0 2.5 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 EMC81304.1 - 0.0022 18.2 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 EMC81304.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 FG-GAP repeat Ank PF00023.25 EMC81305.1 - 5.7e-49 161.5 15.6 1.3e-09 37.3 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.2 EMC81305.1 - 1e-46 157.2 10.5 1.4e-19 70.1 1.5 5.5 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC81305.1 - 1.1e-35 121.3 7.6 4.3e-13 49.3 0.1 6.7 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81305.1 - 2.2e-32 107.8 14.6 1.4e-07 31.0 0.0 8.9 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EMC81305.1 - 1.6e-31 107.6 15.1 4e-08 33.2 0.2 8.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) CLN6 PF15156.1 EMC81306.1 - 1.8e-151 503.0 19.3 2.1e-151 502.8 13.4 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 Zn_dep_PLPC PF00882.13 EMC81306.1 - 0.0089 15.6 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C DUF3397 PF11877.3 EMC81306.1 - 0.041 13.8 0.1 0.041 13.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) Herpes_LMP1 PF05297.6 EMC81306.1 - 0.97 8.2 7.7 0.21 10.4 3.0 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) EF-hand_6 PF13405.1 EMC81307.1 - 1.7e-06 27.3 0.0 3.8e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EMC81307.1 - 3.1e-05 24.0 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC81307.1 - 3.8e-05 22.6 0.1 5.2e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.1 EMC81307.1 - 0.0021 17.9 0.0 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain PINIT PF14324.1 EMC81308.1 - 3.6e-36 124.4 0.1 1e-35 122.9 0.1 1.8 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EMC81308.1 - 2.8e-20 71.5 5.6 5.6e-20 70.5 3.9 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMC81308.1 - 0.00055 19.4 2.0 0.0015 18.0 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EMC81308.1 - 0.98 9.1 5.3 3.8 7.2 3.7 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMC81308.1 - 4.7 6.9 8.6 0.26 10.9 1.7 2.1 2 0 0 2 2 2 0 PHD-finger c-SKI_SMAD_bind PF08782.5 EMC81309.1 - 1e-37 128.1 1.2 1e-37 128.1 0.8 1.7 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Ski_Sno PF02437.12 EMC81309.1 - 8.5e-27 92.9 0.2 1.4e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 SKI/SNO/DAC family Pkinase PF00069.20 EMC81310.1 - 1.5e-58 197.9 0.0 1.9e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81310.1 - 9.9e-39 132.9 0.0 1.3e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC81310.1 - 2.3e-06 26.7 0.0 7.7e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EMC81310.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMC81310.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adaptin_binding PF10199.4 EMC81312.1 - 1.4e-23 83.6 2.6 2.1e-23 83.1 1.8 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.17 EMC81312.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Hrs_helical PF12210.3 EMC81312.1 - 0.11 12.7 0.5 0.25 11.6 0.2 1.6 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MH2 PF03166.9 EMC81313.1 - 3.1e-58 196.5 0.0 3.7e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.4 EMC81313.1 - 0.056 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 Glyco_hydro_1 PF00232.13 EMC81314.1 - 1.8e-162 540.6 6.7 2e-162 540.4 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3377 PF11857.3 EMC81314.1 - 0.06 12.9 0.2 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Glyco_hydro_10 PF00331.15 EMC81314.1 - 0.12 11.3 1.7 5.9 5.8 0.0 2.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 10 DUF2352 PF09817.4 EMC81315.1 - 2.8e-142 474.8 3.1 3.2e-142 474.7 2.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2352) Ribosomal_L4 PF00573.17 EMC81316.1 - 5e-45 153.2 0.1 5e-45 153.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EMC81316.1 - 5.3e-31 106.3 8.4 5.3e-31 106.3 5.9 2.0 1 1 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain SNAPc19 PF15497.1 EMC81317.1 - 1.2e-13 51.0 7.4 1.3e-13 50.8 5.1 1.0 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Pkinase PF00069.20 EMC81318.1 - 1.3e-61 208.0 0.0 1.6e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81318.1 - 1.6e-34 119.1 0.0 7e-33 113.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC81318.1 - 0.0055 15.7 0.0 0.016 14.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMC81318.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4089 PF13318.1 EMC81318.1 - 0.13 12.5 0.8 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Swi3 PF07962.7 EMC81319.1 - 2.3e-36 123.2 0.2 3.6e-36 122.6 0.2 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RNB PF00773.14 EMC81320.1 - 2.6e-85 286.5 0.1 5e-85 285.6 0.1 1.5 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 EMC81320.1 - 0.038 13.4 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain zf-H2C2_2 PF13465.1 EMC81321.1 - 0 976.9 267.0 5.7e-09 35.8 0.2 39.1 39 0 0 39 39 39 39 Zinc-finger double domain zf-C2H2 PF00096.21 EMC81321.1 - 1.5e-189 603.6 349.1 1.8e-06 27.9 1.3 38.9 39 0 0 39 39 39 38 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81321.1 - 1.6e-80 259.6 300.5 0.0061 16.8 0.8 38.2 38 0 0 38 38 38 35 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC81321.1 - 1.7e-67 221.4 267.8 0.0011 18.8 0.7 38.2 38 0 0 38 38 38 34 C2H2-type zinc finger zf-trcl PF13451.1 EMC81321.1 - 5.2e-24 83.6 178.4 0.87 9.2 2.9 35.2 34 3 1 35 35 35 17 Probable zinc-binding domain zf-C2H2_jaz PF12171.3 EMC81321.1 - 5.8e-24 83.5 160.3 0.048 13.8 0.4 33.1 34 0 0 34 34 34 14 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EMC81321.1 - 1.5e-18 66.4 204.0 0.038 13.9 2.6 30.0 12 10 16 29 29 29 18 Zinc ribbon domain KRAB PF01352.22 EMC81321.1 - 2.3e-18 65.3 0.1 4.1e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 KRAB box LIM PF00412.17 EMC81321.1 - 1.1e-09 38.1 211.3 1.9 8.6 2.1 30.5 3 3 34 37 37 37 14 LIM domain zf-LYAR PF08790.6 EMC81321.1 - 1e-08 34.7 218.9 0.019 14.6 0.2 36.4 38 0 0 38 38 38 12 LYAR-type C2HC zinc finger BHD_1 PF10403.4 EMC81321.1 - 9.2e-06 25.0 22.4 8.5 5.9 0.0 13.9 15 3 2 17 17 17 1 Rad4 beta-hairpin domain 1 FokI_N PF02981.10 EMC81321.1 - 0.00036 20.1 0.0 5.6 6.5 0.0 5.6 7 1 0 7 7 7 1 Restriction endonuclease FokI, recognition domain GVQW PF13900.1 EMC81321.1 - 0.7 9.9 15.4 0.32 11.0 0.2 6.1 5 1 1 6 6 6 0 Putative binding domain YhfH PF14149.1 EMC81321.1 - 0.95 9.3 149.6 13 5.6 0.1 32.4 34 0 0 34 34 34 0 YhfH-like protein RNase_T PF00929.19 EMC81322.1 - 3.1e-26 92.6 0.0 9.4e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Exonuclease SAP PF02037.22 EMC81322.1 - 1.5e-07 30.7 0.7 2.7e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 SAP domain DSPc PF00782.15 EMC81323.1 - 7.7e-45 151.7 0.2 9.7e-45 151.4 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC81323.1 - 1.2e-07 31.3 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC81323.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 EMC81323.1 - 0.046 13.1 0.2 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3678 PF12435.3 EMC81323.1 - 1.1 8.9 7.4 0.13 11.8 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Kazal_1 PF00050.16 EMC81324.1 - 2.1e-13 50.0 5.6 2.2e-13 49.9 3.9 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC81324.1 - 9.9e-11 41.3 3.9 1.3e-10 41.0 2.7 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Rtf2 PF04641.7 EMC81325.1 - 0.00041 19.6 0.0 0.00056 19.1 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Homeobox PF00046.24 EMC81326.1 - 4.3e-10 39.0 0.1 5.1e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Homeobox domain Colicin_Pyocin PF01320.13 EMC81326.1 - 0.0045 16.8 0.0 0.0055 16.5 0.0 1.1 1 0 0 1 1 1 1 Colicin immunity protein / pyocin immunity protein Homez PF11569.3 EMC81326.1 - 0.053 12.5 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Arf PF00025.16 EMC81327.1 - 5.6e-37 126.6 0.0 6.3e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC81327.1 - 4.2e-10 39.1 0.0 5.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC81327.1 - 9.1e-09 35.8 0.0 1.4e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMC81327.1 - 7e-08 32.0 0.0 8.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC81327.1 - 6.2e-07 28.7 0.0 8.2e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC81327.1 - 0.0085 14.8 0.0 0.054 12.1 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit AAA PF00004.24 EMC81327.1 - 0.0094 16.1 0.1 0.086 13.0 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EMC81327.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC81327.1 - 0.016 15.1 0.7 0.053 13.4 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EMC81327.1 - 0.054 13.6 0.2 0.3 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC81327.1 - 0.14 12.4 0.1 1 9.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter SRP72 PF08492.7 EMC81328.1 - 2.9e-20 72.4 7.0 2.9e-20 72.4 4.8 2.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.12 EMC81328.1 - 7.7e-15 53.5 14.8 0.0045 16.7 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC81328.1 - 2.2e-14 53.5 19.7 0.0044 17.3 0.0 7.1 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC81328.1 - 8.3e-14 50.8 6.2 0.17 12.5 0.0 8.1 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC81328.1 - 7.4e-11 41.8 17.4 2.4e-07 30.5 0.5 6.4 5 3 1 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC81328.1 - 1.7e-10 40.0 10.7 0.022 14.3 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC81328.1 - 2.7e-10 40.6 7.8 0.16 12.7 0.0 7.1 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC81328.1 - 3e-09 36.3 20.9 0.00051 19.6 0.7 7.8 6 1 3 9 9 8 3 TPR repeat Apc3 PF12895.2 EMC81328.1 - 1.1e-08 35.0 17.1 0.00016 21.7 1.2 6.1 3 3 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC81328.1 - 5.1e-08 32.8 18.0 0.25 11.8 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat BTAD PF03704.12 EMC81328.1 - 5.4e-06 26.7 5.6 0.092 13.0 0.1 4.5 4 1 0 4 4 4 2 Bacterial transcriptional activator domain TPR_8 PF13181.1 EMC81328.1 - 3.5e-05 23.2 10.7 0.46 10.3 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC81328.1 - 0.00092 19.0 6.5 0.93 9.3 0.0 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.15 EMC81328.1 - 0.0015 18.3 0.1 28 4.9 0.0 5.3 5 0 0 5 5 5 0 PPR repeat TPR_7 PF13176.1 EMC81328.1 - 0.0031 17.1 9.6 10 6.1 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC81328.1 - 0.005 16.9 1.0 13 6.2 0.0 5.1 5 0 0 5 5 3 0 Tetratricopeptide repeat RE_Eco47II PF09553.5 EMC81328.1 - 0.0071 15.4 0.2 0.018 14.1 0.1 1.6 1 0 0 1 1 1 1 Eco47II restriction endonuclease ACT_6 PF13740.1 EMC81328.1 - 0.033 13.8 0.1 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 ACT domain Dishevelled PF02377.10 EMC81328.1 - 0.04 14.1 0.1 0.21 11.8 0.1 2.2 2 0 0 2 2 1 0 Dishevelled specific domain PPR_2 PF13041.1 EMC81328.1 - 0.046 13.7 0.1 33 4.5 0.0 4.4 5 0 0 5 5 5 0 PPR repeat family TPR_10 PF13374.1 EMC81328.1 - 0.41 10.6 3.1 19 5.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CorA PF01544.13 EMC81328.1 - 0.93 8.4 4.3 0.24 10.4 0.4 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Vps55 PF04133.9 EMC81329.1 - 8.4e-41 138.4 5.1 9.4e-41 138.3 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 YwiC PF14256.1 EMC81329.1 - 0.0078 16.3 5.1 0.011 15.7 3.6 1.3 1 0 0 1 1 1 1 YwiC-like protein ABC2_membrane PF01061.19 EMC81329.1 - 6.5 5.8 12.4 3.4 6.7 2.4 2.1 2 0 0 2 2 2 0 ABC-2 type transporter DUF1183 PF06682.7 EMC81330.1 - 9.1e-73 245.6 0.1 1e-72 245.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) zf-H2C2_2 PF13465.1 EMC81331.1 - 1.1e-31 107.5 64.1 7.3e-09 35.4 0.8 11.3 11 1 0 11 11 11 7 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMC81331.1 - 6e-21 73.3 74.0 8.8e-05 22.5 1.3 9.5 9 0 0 9 9 9 7 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EMC81331.1 - 1.1e-14 53.8 79.1 0.001 19.3 2.8 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81331.1 - 9.7e-10 38.0 75.1 0.015 15.5 1.8 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC81331.1 - 0.0072 16.4 0.8 0.0072 16.4 0.6 7.5 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC81331.1 - 1.2 9.2 42.6 0.39 10.8 5.0 6.0 2 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) MMR_HSR1 PF01926.18 EMC81332.1 - 9.8e-11 41.6 0.0 2.7e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC81332.1 - 0.00046 20.0 0.1 0.002 17.9 0.1 2.0 1 1 0 1 1 1 1 Dynamin family AAA_29 PF13555.1 EMC81332.1 - 0.0027 17.2 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 EMC81332.1 - 0.025 13.8 0.1 0.057 12.6 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.11 EMC81332.1 - 0.049 12.7 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.22 EMC81332.1 - 0.06 13.6 0.1 0.36 11.1 0.0 2.0 1 1 0 2 2 2 0 ABC transporter SRPRB PF09439.5 EMC81332.1 - 0.16 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_pol_Rpb2_6 PF00562.23 EMC81333.1 - 7.2e-127 423.3 0.3 1.3e-126 422.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMC81333.1 - 8.9e-67 223.9 0.0 1.4e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMC81333.1 - 2.4e-56 190.1 0.0 7.4e-56 188.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMC81333.1 - 4.2e-31 107.0 0.1 1.3e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EMC81333.1 - 9.2e-29 99.0 0.9 1.9e-28 98.0 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EMC81333.1 - 4.9e-22 77.4 0.0 1.1e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EMC81333.1 - 3.7e-20 71.6 0.7 7.4e-20 70.6 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 EMC81333.1 - 0.045 13.5 0.5 0.13 12.1 0.4 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Amidoligase_2 PF12224.3 EMC81333.1 - 0.054 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme I-set PF07679.11 EMC81334.1 - 7.5e-12 44.9 0.1 6e-11 42.0 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC81334.1 - 7e-07 29.2 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC81334.1 - 0.00017 22.0 0.1 0.0023 18.3 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC81334.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 EMC81334.1 - 0.037 13.9 0.0 0.063 13.1 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin V-set domain RCC1 PF00415.13 EMC81335.1 - 3.9e-51 171.0 11.3 7.7e-16 58.0 0.2 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC81335.1 - 1.5e-20 72.2 16.5 5.2e-08 32.3 1.4 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EMC81336.1 - 3.7e-85 279.9 29.5 1.1e-14 54.3 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 EMC81336.1 - 1.5e-83 280.6 0.6 2.1e-83 280.0 0.4 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.1 EMC81336.1 - 1.7e-47 158.0 43.9 2.1e-09 36.7 0.1 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RhoGAP PF00620.22 EMC81337.1 - 2.5e-22 79.1 0.0 3.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain GRIN_C PF15235.1 EMC81338.1 - 7.1e-47 158.9 3.9 7.1e-47 158.9 2.7 2.5 2 0 0 2 2 2 1 G protein-regulated inducer of neurite outgrowth C-terminus PepSY_2 PF13670.1 EMC81338.1 - 0.87 9.5 4.1 0.63 9.9 0.1 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain CENP-C_C PF11699.3 EMC81339.1 - 5.1e-28 96.8 0.3 1.1e-27 95.7 0.2 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EMC81339.1 - 9e-05 21.9 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMC81339.1 - 0.033 13.5 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CLASP_N PF12348.3 EMC81340.1 - 3.8e-12 46.0 0.3 4.2e-12 45.8 0.2 1.0 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 EMC81340.1 - 0.012 15.5 0.4 21 5.5 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 EMC81340.1 - 0.021 15.1 0.1 0.043 14.0 0.1 1.6 1 1 0 1 1 1 0 HEAT repeats DNA_alkylation PF08713.6 EMC81340.1 - 0.088 12.2 0.0 0.24 10.9 0.0 1.6 1 1 1 2 2 2 0 DNA alkylation repair enzyme Pkinase_Tyr PF07714.12 EMC81341.1 - 1e-96 322.9 0.0 1.5e-96 322.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC81341.1 - 2.7e-77 258.5 0.0 4.5e-77 257.8 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC81341.1 - 9.1e-50 169.2 0.0 1.4e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC81341.1 - 2.3e-31 107.7 0.6 2.1e-14 53.3 0.0 3.0 4 0 0 4 4 4 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC81341.1 - 8e-21 74.2 10.3 3.5e-19 68.9 7.1 2.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 EMC81341.1 - 2.3e-09 37.2 0.0 4.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC81341.1 - 6.7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC81341.1 - 4.8e-06 26.0 5.7 4.8e-06 26.0 4.0 2.8 2 2 1 3 3 3 1 GCC2 and GCC3 Interfer-bind PF09294.5 EMC81341.1 - 0.0044 17.0 0.0 0.95 9.5 0.0 3.5 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III Kdo PF06293.9 EMC81341.1 - 0.089 11.8 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.18 EMC81343.1 - 1.4e-71 241.3 0.5 1.6e-71 241.1 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC81343.1 - 1e-13 51.6 0.3 2.8e-13 50.1 0.2 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 EMC81343.1 - 4.7e-10 38.8 0.9 7.5e-10 38.2 0.6 1.3 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.1 EMC81343.1 - 0.0049 17.3 0.0 0.0094 16.4 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease SRCR PF00530.13 EMC81345.1 - 5.2e-45 151.8 19.5 6.3e-27 93.8 5.2 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC81345.1 - 3e-07 30.6 8.0 0.004 17.3 0.1 2.7 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain BRI3BP PF14965.1 EMC81346.1 - 4.9e-29 100.9 3.5 5.5e-29 100.7 2.4 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 DUF2781 PF10914.3 EMC81346.1 - 0.031 14.0 2.4 0.54 10.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2781) YniB PF14002.1 EMC81346.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 YniB-like protein WD40 PF00400.27 EMC81347.1 - 5.8e-43 143.2 12.0 2.7e-11 42.8 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.6 EMC81347.1 - 1.5e-32 111.0 1.9 1.5e-32 111.0 1.3 1.8 2 0 0 2 2 2 1 Prp19/Pso4-like U-box PF04564.10 EMC81347.1 - 1.7e-06 27.9 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain Nup160 PF11715.3 EMC81347.1 - 9.1e-05 20.7 0.9 0.0049 15.0 0.1 2.8 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMC81347.1 - 0.00015 20.2 0.0 0.25 9.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EMC81347.1 - 0.00075 19.2 0.0 0.93 9.1 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-Nse PF11789.3 EMC81347.1 - 0.022 14.2 0.2 0.067 12.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF1830 PF08865.6 EMC81347.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) BAAT_C PF08840.6 EMC81348.1 - 1.1e-51 175.5 0.0 1.2e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EMC81348.1 - 2.7e-07 30.1 0.0 1.6e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC81348.1 - 7.5e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC81348.1 - 2.4e-05 24.3 0.1 6e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMC81348.1 - 0.00025 20.5 0.0 0.00068 19.1 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Bile_Hydr_Trans PF04775.9 EMC81349.1 - 8.9e-35 119.1 0.0 1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region CD20 PF04103.10 EMC81350.1 - 1e-30 106.6 16.0 1.3e-30 106.2 11.1 1.1 1 0 0 1 1 1 1 CD20-like family DUF3413 PF11893.3 EMC81350.1 - 0.0012 17.7 3.3 0.0019 17.1 2.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3413) Pox_A14 PF05767.7 EMC81350.1 - 5 7.1 8.3 2.1 8.3 2.0 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Phage_holin_1 PF04531.8 EMC81350.1 - 7.3 6.7 6.1 1 9.4 0.1 2.4 2 1 1 3 3 3 0 Bacteriophage holin Zona_pellucida PF00100.18 EMC81351.1 - 5.8e-14 52.1 0.0 6.8e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Cobalamin_bind PF01122.14 EMC81352.1 - 9.4e-20 70.4 0.0 1.2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.1 EMC81352.1 - 4.4e-13 49.0 0.0 6.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Ribosomal_L16 PF00252.13 EMC81353.1 - 3.2e-21 75.4 0.1 5.4e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CybS PF05328.7 EMC81353.1 - 0.066 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 CybS Syntaxin PF00804.20 EMC81354.1 - 1.4e-32 111.8 8.9 1.4e-32 111.8 6.2 2.8 3 1 0 3 3 3 1 Syntaxin SNARE PF05739.14 EMC81354.1 - 4e-23 80.8 10.9 4.8e-23 80.6 0.9 3.3 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 EMC81354.1 - 3.2e-05 23.8 8.7 3.2e-05 23.8 6.0 2.7 2 1 1 3 3 3 2 Syntaxin-like protein AAA_13 PF13166.1 EMC81354.1 - 0.018 13.5 15.6 0.024 13.1 10.8 1.1 1 0 0 1 1 1 0 AAA domain MCPsignal PF00015.16 EMC81354.1 - 0.058 12.9 11.6 0.8 9.2 0.5 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Gp_dh_N PF00044.19 EMC81354.1 - 0.058 13.3 0.2 0.19 11.7 0.1 1.9 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SF3b1 PF08920.5 EMC81354.1 - 0.059 13.4 1.7 0.1 12.6 1.2 1.5 1 1 0 1 1 1 0 Splicing factor 3B subunit 1 Baculo_PEP_C PF04513.7 EMC81354.1 - 0.062 13.1 2.7 0.57 10.0 0.4 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 EMC81354.1 - 0.076 12.4 2.9 0.88 9.0 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF872 PF05915.7 EMC81354.1 - 0.09 12.6 0.5 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Syntaxin-6_N PF09177.6 EMC81354.1 - 0.26 11.7 10.5 0.15 12.5 2.2 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal RP-C_C PF11800.3 EMC81354.1 - 0.33 10.6 11.7 0.31 10.7 3.5 2.5 2 1 0 2 2 2 0 Replication protein C C-terminal region DUF2935 PF11155.3 EMC81354.1 - 0.35 10.9 3.2 1.2 9.1 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Phage_GPO PF05929.6 EMC81354.1 - 0.47 9.6 10.3 0.29 10.3 3.9 2.4 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.7 EMC81354.1 - 0.66 9.7 11.2 2.7 7.8 2.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 EMC81354.1 - 0.7 9.9 6.7 12 5.9 0.1 3.5 4 1 0 3 3 3 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 EMC81354.1 - 1.4 8.8 15.4 0.68 9.8 0.6 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DASH_Duo1 PF08651.5 EMC81354.1 - 3.8 7.1 6.9 5.9 6.5 0.1 3.2 3 1 0 3 3 3 0 DASH complex subunit Duo1 Mod_r PF07200.8 EMC81354.1 - 3.9 7.3 15.7 0.46 10.3 3.5 3.0 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.9 EMC81354.1 - 6 6.7 14.7 11 5.9 5.6 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PAT1 PF09770.4 EMC81355.1 - 3.9e-58 197.4 7.0 1.4e-30 106.3 6.0 2.2 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 EF-hand_1 PF00036.27 EMC81356.1 - 4.9e-29 97.3 9.5 9.1e-09 34.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EMC81356.1 - 1.6e-22 78.8 11.1 5.5e-11 41.9 0.7 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EMC81356.1 - 3.2e-22 78.4 4.3 1.4e-12 47.5 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC81356.1 - 3.9e-21 72.9 5.6 9.6e-08 31.3 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EMC81356.1 - 1.4e-20 71.6 10.6 7.9e-07 28.1 0.0 4.9 4 1 1 5 5 5 3 EF hand EF-hand_4 PF12763.2 EMC81356.1 - 1.9e-05 24.3 2.8 0.0017 18.0 0.1 3.0 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC81356.1 - 0.00027 20.7 0.1 0.064 13.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EMC81356.1 - 0.00033 20.6 0.0 0.017 15.1 0.0 2.3 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EMC81356.1 - 0.002 17.8 0.2 0.28 10.9 0.0 2.6 2 1 0 2 2 2 1 Tellurite resistance protein TerB Dockerin_1 PF00404.13 EMC81356.1 - 0.32 10.7 6.4 1.8 8.3 0.1 3.1 3 0 0 3 3 3 0 Dockerin type I repeat DUF1510 PF07423.6 EMC81357.1 - 0.0011 18.4 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF1645 PF07816.6 EMC81357.1 - 0.0096 16.4 0.6 0.012 16.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) U79_P34 PF03064.11 EMC81357.1 - 0.023 14.2 3.8 0.028 13.9 2.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM176 PF14851.1 EMC81357.1 - 0.37 10.4 4.2 0.59 9.8 2.9 1.4 1 0 0 1 1 1 0 FAM176 family Spore_coat_CotO PF14153.1 EMC81357.1 - 0.86 9.0 7.2 1.1 8.7 5.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 EMC81357.1 - 1.2 7.5 10.1 1.3 7.3 7.0 1.0 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EMC81357.1 - 1.5 8.3 11.5 2.1 7.8 8.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin BTV_NS2 PF04514.7 EMC81357.1 - 1.6 7.5 6.4 1.9 7.2 4.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2890 PF11081.3 EMC81357.1 - 2.2 8.3 12.2 2.9 7.9 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Atrophin-1 PF03154.10 EMC81357.1 - 2.8 5.9 7.5 3.3 5.7 5.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family YqfQ PF14181.1 EMC81357.1 - 3.4 7.6 5.1 4.7 7.2 3.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein Nop14 PF04147.7 EMC81357.1 - 4.8 4.9 11.3 5.8 4.7 7.9 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 EMC81357.1 - 6 5.4 11.4 7.2 5.2 7.9 1.0 1 0 0 1 1 1 0 Paf1 Metallophos PF00149.23 EMC81358.1 - 2.2e-44 151.2 0.3 2.7e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PRF PF06875.6 EMC81359.1 - 1.7e-07 30.6 0.0 2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Plethodontid receptivity factor PRF CNTF PF01110.12 EMC81359.1 - 0.00019 20.8 0.0 0.00041 19.6 0.0 1.4 1 1 0 1 1 1 1 Ciliary neurotrophic factor Gly_acyl_tr_N PF06021.6 EMC81360.1 - 7.7e-26 90.7 0.0 3e-17 62.7 0.0 2.1 2 0 0 2 2 2 2 Aralkyl acyl-CoA:amino acid N-acyltransferase Gly_acyl_tr_C PF08444.5 EMC81360.1 - 1.7e-05 24.7 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Autoind_bind PF03472.10 EMC81360.1 - 0.021 14.1 0.1 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain DSPc PF00782.15 EMC81361.1 - 1.2e-29 102.6 0.0 1.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 EMC81361.1 - 4.1e-15 55.3 0.2 6.3e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.22 EMC81361.1 - 0.018 14.3 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pkinase PF00069.20 EMC81362.1 - 9.5e-67 224.8 0.0 2.2e-66 223.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81362.1 - 5e-27 94.6 0.0 7.6e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EMC81362.1 - 2.5e-18 66.2 4.0 4.2e-18 65.5 2.8 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.24 EMC81362.1 - 7.9e-06 26.0 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EMC81362.1 - 0.0037 16.2 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EMC81362.1 - 0.014 15.5 0.3 0.049 13.8 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain zf-CXXC PF02008.15 EMC81363.1 - 1.1e-12 47.5 21.5 1.1e-12 47.5 14.9 2.8 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.28 EMC81363.1 - 6.3e-09 35.2 3.9 6.3e-09 35.2 2.7 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC81363.1 - 3.1e-08 33.2 6.7 6.8e-08 32.1 4.6 1.6 1 0 0 1 1 1 1 F-box-like JmjC PF02373.17 EMC81363.1 - 3.3e-05 24.1 3.9 0.00023 21.3 0.4 3.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase LRR_1 PF00560.28 EMC81363.1 - 0.00046 19.8 5.3 19 5.7 0.1 6.6 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 EMC81363.1 - 0.00082 19.1 9.4 3.8 7.8 0.1 6.2 7 0 0 7 7 6 2 Leucine Rich repeat Cupin_8 PF13621.1 EMC81363.1 - 0.05 13.0 0.2 0.34 10.3 0.2 2.0 1 1 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.17 EMC81363.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin RXT2_N PF08595.6 EMC81363.1 - 0.12 12.1 2.7 6 6.6 0.0 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal LRR_8 PF13855.1 EMC81363.1 - 0.84 9.4 12.1 4.3 7.1 0.0 4.3 3 2 1 5 5 5 0 Leucine rich repeat Myc_N PF01056.13 EMC81363.1 - 1.7 7.7 7.8 1.3 8.0 1.3 2.4 2 0 0 2 2 2 0 Myc amino-terminal region LRR_4 PF12799.2 EMC81363.1 - 1.8 8.3 13.5 12 5.6 0.1 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMC81363.1 - 2 8.9 10.9 76 4.2 0.2 6.1 7 0 0 7 7 6 0 Leucine rich repeat Nucleoplasmin PF03066.10 EMC81363.1 - 4.2 6.8 12.6 0.84 9.1 0.1 2.7 3 0 0 3 3 3 0 Nucleoplasmin Ras PF00071.17 EMC81364.1 - 5.6e-38 129.8 0.0 7.5e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81364.1 - 2.2e-10 41.0 0.0 3.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81364.1 - 0.00041 19.6 0.0 0.00048 19.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family 7tm_1 PF00001.16 EMC81365.1 - 4.9e-17 61.9 33.0 1.4e-16 60.4 22.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC81365.1 - 1.4 8.0 34.6 0.011 14.9 14.1 2.6 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.16 EMC81366.1 - 1.5e-13 50.4 34.6 3.9e-13 49.1 24.0 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC81367.1 - 1.3e-11 44.1 18.7 4.2e-11 42.4 12.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Mtc PF03820.12 EMC81367.1 - 0.098 11.2 0.3 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier 7TM_GPCR_Srbc PF10316.4 EMC81367.1 - 2.7 7.1 21.6 0.013 14.8 5.1 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.16 EMC81368.1 - 3.6e-08 32.8 32.2 1.4e-07 30.9 8.5 3.0 1 1 2 3 3 3 3 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC81369.1 - 5.1e-16 58.5 27.5 5.2e-14 52.0 19.0 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC81369.1 - 3.8e-05 22.9 22.2 3.8e-05 22.9 15.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2953 PF11167.3 EMC81369.1 - 0.0059 16.4 1.5 0.018 14.9 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2953) DUF2830 PF11125.3 EMC81369.1 - 0.018 14.7 0.1 0.081 12.6 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) Sigma_reg_N PF13800.1 EMC81369.1 - 0.56 10.2 6.3 2.6 8.1 1.7 3.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal 7tm_1 PF00001.16 EMC81370.1 - 1.7e-18 66.6 26.1 1.4e-17 63.7 18.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC81370.1 - 1e-06 28.0 23.7 1.6e-06 27.4 15.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2953 PF11167.3 EMC81370.1 - 0.021 14.7 0.4 0.021 14.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) 7TM_GPCR_Srbc PF10316.4 EMC81370.1 - 0.044 13.0 22.4 0.011 15.0 10.7 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc Serpentine_r_xa PF03383.10 EMC81370.1 - 0.072 12.8 11.8 0.28 10.9 7.3 2.3 2 1 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_1 PF00001.16 EMC81371.1 - 2e-15 56.6 25.7 8.6e-14 51.2 17.8 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC81371.1 - 1e-05 24.7 17.2 1e-05 24.7 11.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.4 EMC81371.1 - 3.3e-05 23.2 8.8 3.3e-05 23.2 6.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2953 PF11167.3 EMC81371.1 - 0.047 13.6 0.2 0.047 13.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) 7tm_1 PF00001.16 EMC81372.1 - 9.3e-18 64.2 23.6 2.3e-17 63.0 16.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 EMC81372.1 - 0.054 12.7 19.8 0.19 10.9 13.0 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_4 PF13853.1 EMC81373.1 - 1.3e-27 96.4 16.0 1.3e-27 96.4 11.1 3.8 2 2 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC81373.1 - 1.3e-24 86.7 24.4 3.4e-23 82.0 16.9 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81373.1 - 0.00093 18.4 18.6 0.0023 17.1 12.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC81374.1 - 4.4e-35 120.5 17.2 4.4e-35 120.5 11.9 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC81374.1 - 2e-31 109.0 28.9 2.9e-31 108.5 20.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81374.1 - 0.00054 19.2 26.0 0.0013 17.9 18.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC81375.1 - 4e-42 143.4 9.6 4e-42 143.4 6.7 2.0 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC81375.1 - 5.5e-32 110.9 18.1 7e-32 110.5 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC81376.1 - 7.2e-42 142.5 16.5 7.2e-42 142.5 11.4 2.7 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC81376.1 - 1.4e-32 112.8 27.8 2.3e-32 112.1 19.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81376.1 - 0.00018 20.7 26.8 0.0009 18.4 18.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pex2_Pex12 PF04757.9 EMC81376.1 - 2.8 7.2 5.8 12 5.2 0.0 3.0 2 1 1 3 3 3 0 Pex2 / Pex12 amino terminal region FixQ PF05545.6 EMC81376.1 - 3.7 7.2 0.0 3.7 7.2 0.0 3.8 4 1 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ DUF4133 PF13571.1 EMC81376.1 - 7.8 6.8 19.1 5.8 7.2 2.3 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4133) 7tm_4 PF13853.1 EMC81377.1 - 6.9e-48 162.1 15.9 6.9e-48 162.1 11.0 2.0 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC81377.1 - 1.9e-30 105.8 16.4 2.9e-30 105.2 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ferritin PF00210.19 EMC81378.1 - 1.4e-45 154.5 5.8 1.6e-45 154.3 4.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 EMC81378.1 - 0.0047 17.2 0.5 0.0068 16.7 0.4 1.4 1 0 0 1 1 1 1 Rubrerythrin DUF1215 PF06744.7 EMC81378.1 - 0.095 12.3 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) Bestrophin PF01062.16 EMC81379.1 - 1.2e-89 300.1 0.4 1.4e-89 299.9 0.3 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel G-7-MTase PF12803.2 EMC81379.1 - 0.029 13.5 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Sec2p PF06428.6 EMC81380.1 - 1.8e-26 91.8 5.7 3.9e-26 90.8 4.0 1.5 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 EMC81380.1 - 0.0048 14.6 12.4 0.0066 14.2 8.6 1.1 1 0 0 1 1 1 1 Myosin tail Atg14 PF10186.4 EMC81380.1 - 0.082 11.8 5.4 0.12 11.2 3.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 EMC81380.1 - 0.14 11.1 3.3 0.19 10.6 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IATP PF04568.7 EMC81380.1 - 0.15 12.1 7.7 0.23 11.5 4.6 1.9 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP APG6 PF04111.7 EMC81380.1 - 0.23 10.4 12.7 0.33 9.9 8.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EMC81380.1 - 0.31 10.8 17.6 0.64 9.8 12.2 1.4 1 1 0 1 1 1 0 Tropomyosin like Mnd1 PF03962.10 EMC81380.1 - 0.44 10.1 9.7 0.75 9.4 6.7 1.4 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EMC81380.1 - 0.58 9.7 10.9 0.97 8.9 7.6 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EMC81380.1 - 0.59 8.7 10.7 0.93 8.0 7.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.13 EMC81380.1 - 0.68 9.6 3.8 2.1 8.1 2.6 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF4200 PF13863.1 EMC81380.1 - 0.78 9.6 15.3 1.4 8.8 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HSP70 PF00012.15 EMC81380.1 - 1.1 7.1 6.1 1.5 6.6 4.2 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF342 PF03961.8 EMC81380.1 - 2.5 6.4 6.0 3.4 5.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 EMC81380.1 - 7.5 7.0 11.7 11 6.5 2.1 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FA_desaturase PF00487.19 EMC81381.1 - 3e-30 105.5 23.7 7.1e-30 104.2 13.9 2.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMC81381.1 - 2.9e-22 78.2 0.0 6.2e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CHDNT PF08073.7 EMC81381.1 - 0.012 15.2 0.0 0.045 13.4 0.0 2.0 1 0 0 1 1 1 0 CHDNT (NUC034) domain EpuA PF11772.3 EMC81381.1 - 0.021 14.2 0.1 0.092 12.2 0.1 2.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta FA_desaturase PF00487.19 EMC81382.1 - 2.5e-36 125.4 29.1 2.5e-36 125.4 20.2 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMC81382.1 - 3.3e-18 65.2 0.0 7.4e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EMC81383.1 - 4.1e-40 137.8 19.8 4.1e-40 137.8 13.7 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMC81383.1 - 1.6e-24 85.4 0.1 3.2e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1109 PF06532.6 EMC81383.1 - 0.16 11.3 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) DUF2207 PF09972.4 EMC81383.1 - 1.3 7.4 5.3 0.3 9.5 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 EMC81384.1 - 1e-35 123.4 21.7 1e-35 123.4 15.1 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMC81384.1 - 6.8e-20 70.6 0.0 1.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Catalase PF00199.14 EMC81385.1 - 7.7e-192 637.0 0.0 1.1e-191 636.5 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMC81385.1 - 1.8e-19 69.3 1.9 4.7e-19 68.0 0.3 2.4 3 0 0 3 3 3 1 Catalase-related immune-responsive Ank_2 PF12796.2 EMC81386.1 - 1.3e-33 115.1 5.2 7.5e-18 64.6 0.1 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81386.1 - 2.1e-24 84.0 5.1 2.3e-08 33.4 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat BTB PF00651.26 EMC81386.1 - 3e-24 85.1 0.8 9.2e-24 83.5 0.4 1.9 1 1 1 2 2 2 1 BTB/POZ domain Ank_4 PF13637.1 EMC81386.1 - 8.1e-18 64.4 0.4 1.6e-05 25.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81386.1 - 1.1e-17 62.3 1.2 9e-05 22.3 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EMC81386.1 - 2.4e-13 49.8 3.8 0.00037 20.6 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.10 EMC81386.1 - 0.00062 19.5 0.0 0.0034 17.1 0.0 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch LIM PF00412.17 EMC81388.1 - 1.5e-28 98.6 21.0 1.6e-15 56.9 6.3 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 EMC81388.1 - 0.012 15.5 5.7 0.012 15.5 4.0 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain Vps39_2 PF10367.4 EMC81388.1 - 0.044 13.9 0.7 0.044 13.9 0.5 3.2 1 1 3 4 4 4 0 Vacuolar sorting protein 39 domain 2 Churchill PF06573.6 EMC81388.1 - 0.41 10.6 9.9 0.18 11.7 1.6 2.2 1 1 1 2 2 2 0 Churchill protein DiS_P_DiS PF06750.8 EMC81388.1 - 1.2 9.0 5.7 11 5.9 2.5 2.8 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF525 PF04379.9 EMC81389.1 - 9.1e-28 96.0 0.3 3.9e-27 94.0 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF525) SMI1_KNR4 PF09346.5 EMC81389.1 - 2e-06 27.8 0.0 5.3e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Elongin_A PF06881.6 EMC81389.1 - 0.087 13.2 1.8 0.17 12.2 1.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A UPAR_LY6 PF00021.16 EMC81390.1 - 1.1e-05 25.7 15.9 2.1e-05 24.8 11.0 1.4 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Activin_recp PF01064.18 EMC81390.1 - 0.61 10.7 16.4 1.1 9.9 11.4 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain Actin PF00022.14 EMC81391.1 - 9.7e-162 537.8 0.0 1.1e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Actin RVT_1 PF00078.22 EMC81392.1 - 0.00026 20.4 0.0 0.00029 20.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HS1_rep PF02218.10 EMC81393.1 - 4.2e-107 349.7 62.6 5.9e-22 77.2 5.5 7.6 7 0 0 7 7 7 7 Repeat in HS1/Cortactin SH3_9 PF14604.1 EMC81393.1 - 1.1e-17 63.3 0.2 2.1e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC81393.1 - 1.4e-16 59.6 0.2 3.2e-16 58.4 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC81393.1 - 4.2e-10 38.9 0.0 9.2e-10 37.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.1 EMC81393.1 - 3.2e-05 24.0 0.4 17 5.5 0.0 5.4 3 2 2 6 6 6 2 TMEM210 family AMP-binding_C_2 PF14535.1 EMC81393.1 - 0.021 14.8 0.7 0.21 11.6 0.3 2.6 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain PV-1 PF06637.6 EMC81393.1 - 0.97 7.9 7.3 1.5 7.3 5.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Death PF00531.17 EMC81394.1 - 1.1e-18 66.7 1.7 8.8e-18 63.8 0.1 2.1 2 0 0 2 2 2 1 Death domain DED PF01335.16 EMC81394.1 - 1.3e-16 60.4 3.4 1.3e-16 60.4 2.4 1.6 2 0 0 2 2 2 1 Death effector domain Anoctamin PF04547.7 EMC81395.1 - 1.1e-127 426.4 11.3 1.7e-127 425.7 7.8 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel PspC PF04024.7 EMC81395.1 - 0.18 11.2 0.0 0.18 11.2 0.0 3.8 3 0 0 3 3 3 0 PspC domain FGF PF00167.13 EMC81396.1 - 1.1e-47 160.8 0.3 1.4e-47 160.4 0.2 1.1 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.13 EMC81397.1 - 4.7e-32 110.3 0.1 1.2e-31 108.9 0.0 1.6 2 0 0 2 2 2 1 Fibroblast growth factor FGF PF00167.13 EMC81398.1 - 1.3e-18 66.9 0.0 1.5e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Yae1_N PF09811.4 EMC81399.1 - 1.8e-11 43.3 5.0 3.2e-11 42.5 3.5 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cyclin_N PF00134.18 EMC81400.1 - 1.3e-37 128.1 2.4 1.3e-37 128.1 1.6 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC81400.1 - 2.5e-22 79.0 1.8 1.5e-21 76.5 0.2 2.5 2 1 1 3 3 3 1 Cyclin, C-terminal domain Ion_trans PF00520.26 EMC81401.1 - 4.2e-37 127.3 51.0 3.2e-19 68.9 11.6 3.1 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.7 EMC81401.1 - 8.8 4.6 42.9 2.7 6.3 10.0 4.9 3 2 0 3 3 3 0 Polycystin cation channel NAD_synthase PF02540.12 EMC81402.1 - 2.7e-26 91.9 0.0 6.9e-26 90.6 0.0 1.7 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EMC81402.1 - 3.1e-24 85.3 0.0 5.8e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 EMC81402.1 - 0.0035 16.8 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase ERG4_ERG24 PF01222.12 EMC81403.1 - 8.7e-95 317.7 27.3 1.1e-94 317.4 18.9 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EMC81403.1 - 0.00055 19.3 0.3 0.00055 19.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EMC81403.1 - 0.011 15.9 1.3 0.03 14.5 0.0 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF912 PF06024.7 EMC81403.1 - 0.04 13.9 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ank_2 PF12796.2 EMC81404.1 - 4.5e-40 135.8 0.2 2.6e-14 53.3 0.0 4.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81404.1 - 4.8e-38 127.0 0.3 1.4e-07 30.9 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EMC81404.1 - 5.6e-37 125.4 7.8 1.2e-09 38.3 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC81404.1 - 2.5e-33 113.3 2.3 5.3e-10 39.2 0.3 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 EMC81404.1 - 1.2e-27 96.4 10.6 1.2e-27 96.4 7.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.1 EMC81404.1 - 2.5e-25 85.9 0.2 4.8e-05 23.2 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat zf-RanBP PF00641.13 EMC81404.1 - 0.25 10.5 2.5 0.85 8.7 1.8 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others LIM PF00412.17 EMC81405.1 - 1.1e-29 102.2 25.4 7.9e-17 61.0 3.1 2.1 2 0 0 2 2 2 2 LIM domain Zn_ribbon_2 PF12674.2 EMC81405.1 - 0.16 12.3 14.0 1.3 9.4 2.3 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-TFIIB PF13453.1 EMC81405.1 - 0.27 10.4 9.2 1.2 8.4 0.0 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.1 EMC81405.1 - 0.44 9.8 0.1 0.44 9.8 0.0 4.2 4 2 0 4 4 4 0 zinc-ribbon domain PHF5 PF03660.9 EMC81405.1 - 0.44 10.6 14.3 1.2 9.2 3.4 2.3 2 0 0 2 2 2 0 PHF5-like protein zinc_ribbon_2 PF13240.1 EMC81405.1 - 0.97 9.0 0.0 0.97 9.0 0.0 4.4 5 1 0 5 5 5 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 EMC81405.1 - 1.1 9.0 14.1 1.4 8.6 0.1 4.0 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-C3HC4_2 PF13923.1 EMC81405.1 - 6.7 6.8 20.1 1.8 8.6 0.2 4.3 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) E6 PF00518.12 EMC81405.1 - 8.7 6.7 12.5 1.2 9.4 0.2 2.9 2 2 0 2 2 2 0 Early Protein (E6) E2F_TDP PF02319.15 EMC81406.1 - 4e-43 144.8 0.6 3.6e-21 74.5 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EMC81406.1 - 0.00016 21.3 0.1 0.00063 19.3 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 EMC81406.1 - 0.02 14.7 0.2 7.2 6.5 0.0 2.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Homeobox PF00046.24 EMC81407.1 - 3.4e-21 74.5 4.6 3.8e-21 74.4 2.4 1.7 2 0 0 2 2 2 1 Homeobox domain DUF2986 PF11661.3 EMC81407.1 - 0.0036 17.5 1.1 0.0036 17.5 0.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homez PF11569.3 EMC81407.1 - 0.0094 14.9 0.2 0.02 13.9 0.2 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez PrmA PF06325.8 EMC81408.1 - 1.9e-11 43.6 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EMC81408.1 - 1.7e-10 40.7 0.0 4.4e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC81408.1 - 1.8e-09 38.1 0.2 6.8e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMC81408.1 - 2.8e-09 36.1 0.0 3.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 EMC81408.1 - 2.6e-08 34.2 0.0 6.8e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC81408.1 - 3.3e-08 33.5 0.0 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMC81408.1 - 1.5e-06 27.6 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMC81408.1 - 2.3e-06 27.4 0.0 5.9e-06 26.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.11 EMC81408.1 - 1.1e-05 24.5 0.1 2.4e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 EMC81408.1 - 1.5e-05 25.2 0.1 6.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EMC81408.1 - 0.00025 21.0 0.2 0.0012 18.8 0.1 1.9 1 1 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.11 EMC81408.1 - 0.00028 20.5 0.4 0.00059 19.4 0.1 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_12 PF08242.7 EMC81408.1 - 0.00047 20.5 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC81408.1 - 0.00048 19.2 0.0 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase zf-C2H2_2 PF12756.2 EMC81408.1 - 0.0011 19.0 0.8 0.0033 17.5 0.5 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) TehB PF03848.9 EMC81408.1 - 0.0024 17.0 0.1 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB ATP-synt_B PF00430.13 EMC81408.1 - 0.0066 16.2 0.3 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) PCMT PF01135.14 EMC81408.1 - 0.0071 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EMC81408.1 - 0.02 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EMC81408.1 - 0.034 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1707 PF08044.6 EMC81408.1 - 0.051 13.3 1.7 0.1 12.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Cons_hypoth95 PF03602.10 EMC81408.1 - 0.075 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 EMC81408.1 - 0.11 13.2 0.0 0.72 10.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain zf-C2H2 PF00096.21 EMC81408.1 - 0.2 12.0 1.6 1.4 9.4 1.7 2.1 2 0 0 2 2 1 0 Zinc finger, C2H2 type SNF PF00209.13 EMC81409.1 - 7.7e-216 717.5 42.4 2.2e-215 716.0 29.4 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family EGF_CA PF07645.10 EMC81410.1 - 2.5e-26 91.3 54.6 6.3e-11 42.0 3.7 11.1 10 2 2 12 12 6 4 Calcium-binding EGF domain VWC PF00093.13 EMC81410.1 - 4.1e-20 71.6 78.1 1.4e-10 41.0 10.7 9.9 6 1 2 8 8 7 5 von Willebrand factor type C domain EGF_3 PF12947.2 EMC81410.1 - 3e-12 46.2 37.6 2e-09 37.2 10.2 10.9 10 0 0 10 10 8 4 EGF domain cEGF PF12662.2 EMC81410.1 - 1.4e-09 37.4 10.9 9.8e-08 31.5 1.7 11.0 11 0 0 11 11 11 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.19 EMC81410.1 - 1.5e-09 37.9 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 EMC81410.1 - 6.5e-07 29.1 38.7 0.00013 21.8 2.4 11.1 12 1 0 12 12 10 5 EGF-like domain Laminin_G_3 PF13385.1 EMC81410.1 - 6.6e-07 29.6 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 EMC81410.1 - 4.4e-05 23.5 0.0 0.00011 22.1 0.0 1.6 1 1 0 1 1 1 1 Laminin G domain TILa PF12714.2 EMC81410.1 - 0.00027 20.6 11.0 0.00027 20.6 7.6 11.2 5 3 6 11 11 8 3 TILa domain hEGF PF12661.2 EMC81410.1 - 0.00034 20.4 3.0 0.00034 20.4 2.1 12.2 12 0 0 12 12 10 2 Human growth factor-like EGF EGF_2 PF07974.8 EMC81410.1 - 0.002 18.2 14.2 0.002 18.2 9.8 13.1 10 3 2 12 12 11 2 EGF-like domain FXa_inhibition PF14670.1 EMC81410.1 - 0.0089 16.1 7.7 0.0089 16.1 5.3 10.9 8 2 3 11 11 7 3 Coagulation Factor Xa inhibitory site RhoGAP PF00620.22 EMC81412.1 - 4.2e-30 104.3 0.1 6.4e-30 103.7 0.1 1.3 1 1 0 1 1 1 1 RhoGAP domain Steroid_dh PF02544.11 EMC81413.1 - 3.3e-20 72.3 5.9 3.3e-20 72.3 4.1 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1513 PF07433.6 EMC81415.1 - 5.1 5.9 4.7 3.8 6.3 0.3 2.8 1 1 2 4 4 4 0 Protein of unknown function (DUF1513) AT_hook PF02178.14 EMC81417.1 - 0.00021 20.6 23.0 0.0018 17.7 2.3 3.1 3 1 0 3 3 3 2 AT hook motif mono-CXXC PF15626.1 EMC81417.1 - 4.9 7.1 5.4 2.2 8.3 2.4 1.5 1 1 1 2 2 2 0 single CXXC unit RFX5_DNA_bdg PF14621.1 EMC81417.1 - 7.3 6.1 10.8 0.5 9.9 3.2 1.7 1 1 1 2 2 2 0 RFX5 DNA-binding domain SelR PF01641.13 EMC81418.1 - 7.6e-52 174.2 0.1 9.7e-52 173.8 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EMC81418.1 - 0.022 14.5 0.6 0.19 11.6 0.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF2961 PF11175.3 EMC81418.1 - 0.031 13.6 0.1 0.043 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Yippee-Mis18 PF03226.9 EMC81418.1 - 0.041 13.9 0.3 0.18 11.8 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_2 PF13240.1 EMC81418.1 - 0.048 13.1 0.6 2 7.9 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EMC81418.1 - 0.076 12.9 1.7 1.5 8.7 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.1 EMC81418.1 - 0.14 12.0 4.0 0.54 10.1 0.1 2.8 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HYPF PF07503.7 EMC81418.1 - 0.31 10.4 1.8 1.7 8.1 0.1 2.8 3 0 0 3 3 3 0 HypF finger zf-HIT PF04438.11 EMC81418.1 - 0.37 10.4 3.3 6 6.6 0.0 2.8 2 1 0 2 2 2 0 HIT zinc finger Auto_anti-p27 PF06677.7 EMC81418.1 - 0.4 10.4 4.5 1.3 8.8 0.1 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-tcix PF14952.1 EMC81418.1 - 2.1 7.7 6.6 14 5.1 0.1 3.3 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding RabGAP-TBC PF00566.13 EMC81419.1 - 1.5e-39 135.6 0.1 3.2e-39 134.6 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 60KD_IMP PF02096.15 EMC81419.1 - 0.67 9.5 4.8 0.14 11.8 0.5 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein NYD-SP28 PF14772.1 EMC81420.1 - 0.12 12.4 0.8 0.2 11.7 0.6 1.5 1 1 0 1 1 1 0 Sperm tail DUF733 PF05306.6 EMC81420.1 - 0.28 11.5 2.0 0.36 11.1 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF733) RA PF00788.18 EMC81421.1 - 1.7e-23 82.9 0.2 1.9e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 EMC81421.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 EF-hand_like PF09279.6 EMC81421.1 - 0.095 12.7 1.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Pepsin-I3 PF06394.8 EMC81421.1 - 0.3 10.7 2.2 0.74 9.5 0.1 2.4 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain Pkinase PF00069.20 EMC81422.1 - 1.1e-48 165.6 0.0 2.1e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81422.1 - 7.5e-26 90.7 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC81422.1 - 9e-05 21.5 0.0 0.0012 17.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like ubiquitin PF00240.18 EMC81422.1 - 0.0038 16.5 0.2 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family NPV_P10 PF05531.7 EMC81422.1 - 0.013 15.7 0.9 2 8.6 0.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APH PF01636.18 EMC81422.1 - 0.072 12.8 0.0 1.6 8.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family IncA PF04156.9 EMC81422.1 - 2.6 7.6 7.2 0.46 10.0 0.3 2.6 2 1 0 2 2 2 0 IncA protein Ribosomal_L18ae PF01775.12 EMC81423.1 - 1.1e-57 193.2 0.1 1.5e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF2003 PF09404.5 EMC81425.1 - 1.1e-270 897.5 5.0 1.2e-270 897.4 3.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) RhoGAP PF00620.22 EMC81426.1 - 2.5e-46 157.0 0.3 2.6e-45 153.7 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EMC81426.1 - 5e-19 68.2 6.1 2.5e-18 66.0 4.2 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMC81426.1 - 8e-11 41.3 0.0 1.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC81426.1 - 2.3e-10 39.6 0.0 4.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC81426.1 - 4.7e-09 35.5 0.0 9.9e-09 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 EMC81426.1 - 0.01 15.7 0.8 0.063 13.1 0.6 2.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2827 PF10933.3 EMC81427.1 - 0.0027 16.2 0.0 0.004 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2827) Exostosin PF03016.10 EMC81427.1 - 0.0037 16.3 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Flg_bbr_C PF06429.8 EMC81427.1 - 0.015 15.2 0.2 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal 7tm_1 PF00001.16 EMC81428.1 - 6.6e-24 84.4 0.2 7.6e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1856 PF08983.5 EMC81428.1 - 1.2e-11 44.5 7.8 2e-11 43.7 5.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1856) 7TM_GPCR_Srsx PF10320.4 EMC81428.1 - 0.018 14.2 0.7 0.021 13.9 0.5 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Srg PF02118.16 EMC81428.1 - 0.026 13.9 0.3 0.033 13.6 0.2 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor Orai-1 PF07856.7 EMC81428.1 - 0.047 13.2 0.5 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Mediator of CRAC channel activity Amastin PF07344.6 EMC81428.1 - 0.056 13.0 0.4 0.092 12.3 0.3 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein 7TM_GPCR_Srv PF10323.4 EMC81428.1 - 0.098 11.7 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC81428.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PP2C PF00481.16 EMC81429.1 - 2.5e-28 99.1 0.0 4.2e-12 45.9 0.0 3.1 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.7 EMC81429.1 - 2.2e-05 24.2 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EMC81429.1 - 0.00017 21.0 0.0 0.0031 16.9 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_hydro_38C PF07748.8 EMC81430.1 - 4.6e-83 279.5 4.8 5.8e-83 279.2 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 EMC81430.1 - 1.2e-73 247.8 3.3 1.8e-73 247.1 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EMC81430.1 - 4.8e-16 58.7 0.0 1.3e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain S_100 PF01023.14 EMC81431.1 - 1.5e-17 62.5 0.1 5.8e-17 60.7 0.0 2.0 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_6 PF13405.1 EMC81431.1 - 1.2e-07 30.9 0.4 0.00089 18.9 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EMC81431.1 - 3.1e-07 30.4 0.2 4.4e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC81431.1 - 2.2e-06 26.5 0.9 2.4e-05 23.3 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC81431.1 - 0.00031 20.3 0.2 0.00044 19.8 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 EMC81431.1 - 0.0088 15.7 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EMC81431.1 - 0.024 13.9 2.7 0.38 10.1 0.8 2.5 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 EMC81431.1 - 0.077 13.0 0.5 0.15 12.1 0.4 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EMC81431.1 - 0.14 11.8 1.7 1.4 8.6 0.0 2.8 3 1 0 3 3 3 0 EF hand KID PF02524.9 EMC81431.1 - 0.16 12.1 1.5 0.67 10.3 0.2 2.5 2 0 0 2 2 2 0 KID repeat RabGAP-TBC PF00566.13 EMC81432.1 - 1.2e-47 162.1 0.0 2.6e-47 161.0 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SWIRM PF04433.12 EMC81433.1 - 8.5e-05 22.6 0.3 0.00031 20.8 0.0 2.2 2 1 0 2 2 2 1 SWIRM domain Pertussis_S1 PF02917.9 EMC81433.1 - 0.047 13.2 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 GrpE PF01025.14 EMC81434.1 - 3.3e-46 156.8 4.5 4e-46 156.5 3.1 1.1 1 0 0 1 1 1 1 GrpE Laminin_I PF06008.9 EMC81434.1 - 0.0064 15.8 7.6 0.0081 15.5 5.3 1.1 1 0 0 1 1 1 1 Laminin Domain I Cpn60_TCP1 PF00118.19 EMC81434.1 - 0.03 12.9 2.1 0.037 12.6 1.4 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Terpene_synth PF01397.16 EMC81434.1 - 0.048 13.0 3.5 0.067 12.5 2.4 1.2 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain LRAT PF04970.8 EMC81434.1 - 0.11 12.4 0.8 0.17 11.8 0.6 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF1993 PF09351.5 EMC81434.1 - 0.12 12.2 3.2 3.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Atg14 PF10186.4 EMC81434.1 - 0.15 10.9 5.2 0.18 10.6 3.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bac_GDH PF05088.7 EMC81434.1 - 0.3 8.4 3.9 0.36 8.1 2.7 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase eIF3_subunit PF08597.5 EMC81434.1 - 0.4 10.2 11.0 0.55 9.7 7.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2205 PF10224.4 EMC81434.1 - 0.62 9.6 7.6 0.51 9.9 3.9 1.8 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF3391 PF11871.3 EMC81434.1 - 0.63 10.2 5.3 2.1 8.5 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF1115 PF06544.7 EMC81434.1 - 5.5 6.6 6.4 22 4.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1115) DUF972 PF06156.8 EMC81434.1 - 7.2 7.0 10.6 0.39 11.0 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EMC81434.1 - 9.8 5.7 15.2 17 4.9 10.5 1.5 1 1 0 1 1 1 0 IncA protein PKD PF00801.15 EMC81435.1 - 7.6e-08 31.9 0.0 2.8e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 PKD domain BNR PF02012.15 EMC81435.1 - 4e-05 22.8 4.9 1.4 9.0 0.2 5.1 4 0 0 4 4 4 2 BNR/Asp-box repeat PH PF00169.24 EMC81436.1 - 2.2e-26 92.0 4.7 6.8e-14 51.9 1.3 3.0 3 0 0 3 3 3 2 PH domain ERM PF00769.14 EMC81436.1 - 1.3e-05 24.8 7.6 1.3e-05 24.8 5.3 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family PH_9 PF15410.1 EMC81436.1 - 0.0002 21.5 1.3 0.9 9.7 0.3 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EMC81436.1 - 0.0046 17.1 5.9 0.33 11.2 0.2 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain APG6 PF04111.7 EMC81436.1 - 0.48 9.4 12.3 1.1 8.2 8.5 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMC81436.1 - 2.8 5.7 4.1 4.3 5.0 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 EMC81436.1 - 3.5 7.4 19.3 0.62 9.8 3.1 3.0 3 0 0 3 3 3 0 Prefoldin subunit LIM PF00412.17 EMC81437.1 - 2.5e-39 133.1 45.1 1.6e-14 53.6 2.7 4.3 4 0 0 4 4 4 4 LIM domain VHP PF02209.14 EMC81437.1 - 5.1e-17 61.2 2.3 8.7e-17 60.5 1.6 1.4 1 0 0 1 1 1 1 Villin headpiece domain TPR_12 PF13424.1 EMC81438.1 - 5.5e-19 67.8 48.6 4.8e-05 23.2 0.2 8.4 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMC81438.1 - 7.8e-05 22.3 45.7 0.31 11.0 0.3 11.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMC81438.1 - 0.00023 20.6 36.3 0.22 11.2 0.0 10.0 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMC81438.1 - 0.00033 20.2 43.8 0.042 13.4 1.8 8.6 7 2 2 9 9 9 3 TPR repeat SH3_1 PF00018.23 EMC81438.1 - 0.00063 19.0 0.5 0.0015 17.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain TPR_8 PF13181.1 EMC81438.1 - 0.0011 18.5 39.3 0.0059 16.3 0.1 11.4 11 1 1 12 12 12 1 Tetratricopeptide repeat SH3_2 PF07653.12 EMC81438.1 - 0.0016 17.8 0.0 0.0041 16.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TPR_14 PF13428.1 EMC81438.1 - 0.01 16.3 12.3 36 5.3 0.0 7.5 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC81438.1 - 0.026 14.4 13.1 22 5.1 0.2 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC81438.1 - 0.056 14.1 24.2 0.88 10.3 0.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat SH3_9 PF14604.1 EMC81438.1 - 0.073 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain TPR_21 PF09976.4 EMC81438.1 - 0.084 12.8 1.8 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC81438.1 - 1.4 8.9 24.1 0.27 11.1 0.1 8.2 9 1 1 10 10 10 0 Tetratricopeptide repeat Trypsin_2 PF13365.1 EMC81439.1 - 1.6e-19 70.0 0.5 5.3e-19 68.3 0.2 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 EMC81439.1 - 4.6e-15 55.8 0.0 7.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EMC81439.1 - 1.8e-10 40.5 0.1 7.2e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 EMC81439.1 - 2.9e-09 36.9 0.0 9.1e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Kazal_2 PF07648.10 EMC81439.1 - 1.3e-06 28.2 1.5 2.8e-06 27.1 1.1 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC81439.1 - 4.5e-06 26.5 1.7 4.5e-06 26.5 1.2 2.5 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Peptidase_S46 PF10459.4 EMC81439.1 - 5.7e-05 21.7 2.0 0.067 11.6 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.8 EMC81439.1 - 0.001 18.1 0.3 0.47 9.3 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 IGFBP PF00219.13 EMC81439.1 - 0.0012 19.2 22.6 0.0012 19.2 15.7 1.8 2 0 0 2 2 1 1 Insulin-like growth factor binding protein Tricorn_PDZ PF14685.1 EMC81439.1 - 0.0034 17.1 0.1 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 Tricorn protease PDZ domain DUF31 PF01732.11 EMC81439.1 - 0.13 11.5 0.9 11 5.2 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) ACOX PF01756.14 EMC81440.1 - 2.3e-47 160.7 0.0 3.7e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EMC81440.1 - 9.5e-13 47.4 0.2 1.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMC81440.1 - 6.4e-08 32.8 0.1 6.5e-07 29.5 0.1 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EMC81440.1 - 2.5e-06 27.8 0.0 5.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal AdoMet_MTase PF07757.8 EMC81441.1 - 6.5e-41 138.9 0.1 1.4e-40 137.9 0.1 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EMC81441.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC81441.1 - 0.01 15.4 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 EMC81441.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 EMC81441.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EMC81441.1 - 0.061 12.9 0.3 0.2 11.3 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain 7tm_1 PF00001.16 EMC81442.1 - 4.1e-38 130.9 19.4 4.9e-38 130.7 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PGG PF13962.1 EMC81442.1 - 0.027 14.0 1.0 0.027 14.0 0.7 2.2 3 0 0 3 3 3 0 Domain of unknown function gpUL132 PF11359.3 EMC81442.1 - 1.4 8.1 7.0 0.41 9.9 1.7 2.1 2 0 0 2 2 2 0 Glycoprotein UL132 Peptidase_M14 PF00246.19 EMC81443.1 - 1.9e-78 263.9 0.0 2.4e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Fz PF01392.17 EMC81443.1 - 5.8e-20 71.7 3.7 1.4e-19 70.5 2.6 1.7 1 0 0 1 1 1 1 Fz domain CarboxypepD_reg PF13620.1 EMC81443.1 - 4.5e-15 55.4 0.0 8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMC81443.1 - 7.8e-08 32.2 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Glypican PF01153.14 EMC81443.1 - 0.0072 14.9 1.6 0.011 14.3 1.1 1.1 1 0 0 1 1 1 1 Glypican AstE_AspA PF04952.9 EMC81443.1 - 0.046 12.5 0.1 1.9 7.2 0.1 2.6 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family 7tm_1 PF00001.16 EMC81444.1 - 9.7e-80 267.4 5.6 1.5e-79 266.8 3.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81444.1 - 9e-11 41.4 15.7 4.7e-08 32.5 3.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC81444.1 - 3.6e-06 26.3 17.1 1e-05 24.8 5.0 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx IL8 PF00048.15 EMC81445.1 - 1e-19 70.2 0.7 1.4e-19 69.8 0.5 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Alpha-2-MRAP_C PF06401.6 EMC81446.1 - 8.6e-101 336.2 29.0 8.6e-101 336.2 20.1 1.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.6 EMC81446.1 - 4.1e-30 103.9 22.4 9.3e-30 102.7 2.1 3.5 3 1 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain Med30 PF11315.3 EMC81446.1 - 0.0053 16.9 4.2 0.0053 16.9 2.9 2.1 1 1 1 2 2 2 1 Mediator complex subunit 30 Spectrin PF00435.16 EMC81446.1 - 0.015 15.5 15.2 0.16 12.2 4.1 2.8 2 1 0 2 2 2 0 Spectrin repeat PriCT_2 PF08707.6 EMC81446.1 - 0.03 14.1 0.7 0.36 10.7 0.1 2.4 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Mod_r PF07200.8 EMC81446.1 - 0.55 10.1 18.0 0.075 12.9 2.8 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Trypsin PF00089.21 EMC81447.1 - 1.9e-73 246.6 0.3 2.1e-73 246.5 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC81447.1 - 3.8e-06 26.4 0.1 6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) fn2 PF00040.14 EMC81448.1 - 2.5e-14 52.9 6.3 5.1e-14 51.9 4.4 1.6 1 0 0 1 1 1 1 Fibronectin type II domain IN_DBD_C PF00552.16 EMC81448.1 - 0.15 11.5 0.3 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Integrase DNA binding domain RBD PF02196.10 EMC81449.1 - 4.5e-36 122.4 0.3 7.6e-20 70.4 0.0 2.8 3 0 0 3 3 3 2 Raf-like Ras-binding domain RGS PF00615.14 EMC81449.1 - 1.8e-28 99.0 3.6 3.2e-28 98.1 2.5 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PDZ PF00595.19 EMC81449.1 - 9.7e-14 51.3 0.1 1.1e-12 47.9 0.0 2.8 2 1 1 3 3 3 1 PDZ domain (Also known as DHR or GLGF) GoLoco PF02188.12 EMC81449.1 - 1.8e-09 36.6 0.2 1.8e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 GoLoco motif PID PF00640.18 EMC81449.1 - 6.9e-05 22.8 0.1 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ_2 PF13180.1 EMC81449.1 - 0.00078 19.2 0.1 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain TUG-UBL1 PF11470.3 EMC81449.1 - 0.0012 18.6 0.0 0.092 12.6 0.0 2.8 2 0 0 2 2 2 1 GLUT4 regulating protein TUG Myb_DNA-bind_4 PF13837.1 EMC81450.1 - 1.3e-11 44.4 1.3 1.3e-11 44.4 0.9 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain GPI PF06560.6 EMC81450.1 - 0.084 11.8 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MADF_DNA_bdg PF10545.4 EMC81450.1 - 0.13 12.4 0.2 0.13 12.4 0.1 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TipAS PF07739.8 EMC81450.1 - 2.4 8.5 6.5 0.49 10.7 0.3 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Vac14_Fab1_bd PF12755.2 EMC81451.1 - 0.0079 16.5 0.1 0.0085 16.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region Spatacsin_C PF14649.1 EMC81451.1 - 0.017 14.0 0.4 0.018 13.9 0.3 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus VPS9 PF02204.13 EMC81451.1 - 0.02 14.9 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain HEAT PF02985.17 EMC81451.1 - 0.025 14.6 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat Pkinase PF00069.20 EMC81452.1 - 1.5e-59 201.2 0.0 1.9e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81452.1 - 8.7e-34 116.7 0.0 1.2e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EMC81452.1 - 2.5e-21 75.9 0.1 5.3e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.1 EMC81452.1 - 0.00027 19.9 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Nop14 PF04147.7 EMC81453.1 - 3e-256 852.5 36.4 3.7e-256 852.2 25.3 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2810 PF10928.3 EMC81453.1 - 0.00041 20.0 0.4 0.097 12.4 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2810) PAP_central PF04928.12 EMC81453.1 - 0.6 8.8 4.0 2.2 7.0 2.8 1.9 1 0 0 1 1 1 0 Poly(A) polymerase central domain MFS_1 PF07690.11 EMC81454.1 - 1.8e-34 119.0 48.0 3.2e-29 101.7 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC81454.1 - 3.7e-11 42.2 11.5 3.7e-11 42.2 8.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMC81454.1 - 1.3e-05 23.6 3.9 1.3e-05 23.6 2.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NTS_2 PF15448.1 EMC81454.1 - 0.16 12.2 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein Papilloma_E5 PF03025.9 EMC81454.1 - 4.8 7.1 12.2 3.2 7.7 0.5 3.7 4 0 0 4 4 4 0 Papillomavirus E5 Aldolase_II PF00596.16 EMC81455.1 - 3.4e-44 150.6 0.1 5e-44 150.1 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PH PF00169.24 EMC81456.1 - 1e-14 54.5 0.2 2.1e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 PH domain SH2 PF00017.19 EMC81456.1 - 3.2e-06 26.8 0.0 7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PH_6 PF15406.1 EMC81456.1 - 0.0043 17.0 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain TMEM171 PF15471.1 EMC81456.1 - 0.065 12.0 2.7 0.15 10.7 1.9 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 EABR PF12180.3 EMC81457.1 - 1.7e-18 65.6 3.8 1.7e-18 65.6 2.6 2.5 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 FlxA PF14282.1 EMC81457.1 - 0.0008 19.3 7.2 0.0008 19.3 5.0 5.9 1 1 4 5 5 5 1 FlxA-like protein Cons_hypoth95 PF03602.10 EMC81457.1 - 0.039 13.3 0.5 0.13 11.6 0.3 1.9 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF1192 PF06698.6 EMC81457.1 - 0.058 13.2 0.5 0.058 13.2 0.3 4.9 5 1 1 6 6 6 0 Protein of unknown function (DUF1192) GvpK PF05121.7 EMC81457.1 - 0.77 9.6 17.0 3.2 7.6 1.5 4.5 3 1 1 4 4 4 0 Gas vesicle protein K Octopine_DH PF02317.12 EMC81457.1 - 1.5 8.4 6.2 0.59 9.7 0.3 2.4 2 1 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Tropomyosin_1 PF12718.2 EMC81457.1 - 2.4 8.0 57.9 0.19 11.5 11.6 4.2 1 1 2 4 4 4 0 Tropomyosin like ATG16 PF08614.6 EMC81457.1 - 3 7.6 54.5 2.6 7.8 16.2 4.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EMC81457.1 - 7.5 5.5 55.5 6.5 5.7 11.5 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 Spc7 PF08317.6 EMC81457.1 - 8.1 5.0 49.9 0.73 8.4 11.3 3.4 1 1 2 4 4 4 0 Spc7 kinetochore protein zf-RING_2 PF13639.1 EMC81459.1 - 4.5e-14 51.9 8.0 8e-14 51.1 4.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC81459.1 - 3.1e-10 39.8 7.2 6.7e-10 38.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC81459.1 - 8.4e-10 38.1 6.4 1.6e-09 37.2 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC81459.1 - 1.2e-09 37.6 5.8 2.2e-09 36.7 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC81459.1 - 5e-09 35.7 6.6 9.8e-09 34.8 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EMC81459.1 - 3.4e-06 26.5 3.7 9.1e-06 25.1 2.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EMC81459.1 - 4.6e-06 26.6 0.8 1e-05 25.5 0.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC81459.1 - 3.7e-05 23.3 2.6 0.00022 20.9 1.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC81459.1 - 0.00064 19.5 9.9 0.015 15.1 6.9 2.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EMC81459.1 - 0.0013 18.2 4.2 0.0025 17.3 0.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.1 EMC81459.1 - 0.011 15.4 6.0 0.014 15.1 1.5 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger Rtf2 PF04641.7 EMC81459.1 - 0.013 14.7 6.3 0.031 13.4 4.4 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_6 PF14835.1 EMC81459.1 - 0.014 15.1 5.2 0.088 12.6 3.6 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.6 EMC81459.1 - 0.13 12.1 5.8 0.32 10.8 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-P11 PF03854.9 EMC81459.1 - 0.16 11.4 7.3 0.049 13.1 2.3 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-Apc11 PF12861.2 EMC81459.1 - 0.21 11.4 3.6 0.42 10.4 2.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EMC81459.1 - 0.22 11.5 5.5 5.2 7.1 3.8 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.2 EMC81459.1 - 0.32 10.8 7.3 0.099 12.4 1.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Nse PF11789.3 EMC81459.1 - 0.89 9.1 7.1 1.8 8.1 3.8 2.4 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.7 EMC81459.1 - 1.4 8.8 7.1 5.7 6.8 5.0 2.0 1 1 0 1 1 1 0 zinc-ribbons DUF329 PF03884.9 EMC81459.1 - 4 7.0 7.4 3.9 7.1 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF329) Zn-ribbon_8 PF09723.5 EMC81459.1 - 5.6 6.9 7.3 4 7.4 2.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.16 EMC81459.1 - 6.1 6.8 12.8 3 7.7 4.8 2.7 2 1 1 3 3 3 0 FYVE zinc finger IBR PF01485.16 EMC81459.1 - 7.5 6.5 9.3 45 4.0 6.4 2.5 1 1 1 2 2 2 0 IBR domain FYVE PF01363.16 EMC81460.1 - 1.4e-19 69.7 12.1 1.4e-19 69.7 8.4 3.1 3 1 0 3 3 3 1 FYVE zinc finger HLH PF00010.21 EMC81461.1 - 1.8e-10 40.3 3.2 6.3e-10 38.6 1.8 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Anthrax_toxA PF03497.11 EMC81461.1 - 0.0014 18.4 6.0 0.21 11.3 0.7 2.1 1 1 1 2 2 2 2 Anthrax toxin LF subunit ATP-synt_ab_C PF00306.22 EMC81461.1 - 0.097 13.1 1.7 0.15 12.5 1.2 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain HAUS-augmin3 PF14932.1 EMC81462.1 - 7.3e-61 205.5 27.4 7.3e-61 205.5 19.0 4.2 2 1 2 4 4 4 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 EMC81462.1 - 0.0077 16.0 31.2 0.077 12.8 3.9 4.7 4 1 0 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus WD40_alt PF14077.1 EMC81462.1 - 0.058 13.0 4.2 4.7 6.9 0.0 4.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif Acetyltransf_11 PF13720.1 EMC81462.1 - 7.8 6.8 13.5 6.4 7.0 0.6 4.8 3 1 2 5 5 5 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DNA_pol_A PF00476.15 EMC81463.1 - 2.2e-80 270.1 2.4 3e-80 269.6 1.6 1.2 1 0 0 1 1 1 1 DNA polymerase family A Acetyltransf_1 PF00583.19 EMC81464.1 - 6.8e-16 58.0 0.1 9.4e-16 57.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC81464.1 - 3e-11 43.3 0.0 4.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC81464.1 - 1.3e-08 34.9 0.2 2.2e-08 34.2 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMC81464.1 - 5.9e-08 32.7 0.1 1.7e-07 31.2 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMC81464.1 - 5.3e-07 29.4 0.0 1.7e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EMC81464.1 - 1.1e-05 25.5 0.1 1.5e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC81464.1 - 9.5e-05 22.3 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC81464.1 - 0.00059 19.6 0.2 0.0096 15.7 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC81464.1 - 0.00075 19.2 1.2 0.0019 17.9 0.1 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_5 PF13444.1 EMC81464.1 - 0.11 13.0 0.1 0.35 11.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Neuropep_like PF15161.1 EMC81465.1 - 1.1e-28 98.5 0.2 1.6e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 Neuropeptide-like PAT1 PF09770.4 EMC81466.1 - 1.7 6.7 16.3 2 6.5 11.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LETM1 PF07766.8 EMC81467.1 - 4.7e-95 317.6 11.2 4.7e-95 317.6 7.7 3.7 3 2 0 3 3 3 1 LETM1-like protein EF-hand_7 PF13499.1 EMC81467.1 - 0.0054 16.8 0.9 0.039 14.0 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair Acetyltransf_11 PF13720.1 EMC81467.1 - 0.0097 16.1 0.7 0.086 13.0 0.1 3.0 2 0 0 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_1 PF00036.27 EMC81467.1 - 0.018 14.3 0.3 0.18 11.2 0.1 2.6 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.1 EMC81467.1 - 0.035 13.4 0.2 0.16 11.3 0.2 2.2 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EMC81467.1 - 0.074 12.9 0.2 1.7 8.7 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain DUF3573 PF12097.3 EMC81467.1 - 7.9 4.9 7.6 54 2.2 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3573) Pkinase_Tyr PF07714.12 EMC81468.1 - 5.3e-104 346.8 0.0 7.3e-104 346.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC81468.1 - 2.1e-48 164.7 0.0 2.9e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 EMC81468.1 - 5.3e-38 128.7 0.0 4.5e-14 52.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC81468.1 - 1.5e-29 101.9 0.4 2.3e-09 37.2 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 EMC81468.1 - 2e-21 75.8 7.3 1.5e-06 28.2 0.0 4.4 4 1 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 EMC81468.1 - 2.9e-21 75.7 2.7 7.1e-08 32.8 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC81468.1 - 1.5e-15 57.0 6.8 0.00015 21.5 0.1 5.8 4 3 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC81468.1 - 0.00025 20.8 0.2 0.027 14.3 0.0 3.3 2 1 2 4 4 4 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 EMC81468.1 - 0.0066 16.2 0.1 0.82 9.4 0.0 3.2 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Shisa PF13908.1 EMC81468.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.6 EMC81468.1 - 0.095 12.4 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Tex_N PF09371.5 EMC81469.1 - 2.9e-47 160.5 0.3 4.9e-47 159.7 0.2 1.3 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HTH_44 PF14641.1 EMC81469.1 - 0.0079 16.1 0.9 0.02 14.8 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 UPF0081 PF03652.10 EMC81469.1 - 0.0089 16.1 0.0 0.03 14.4 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0081) DUF885 PF05960.6 EMC81469.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) C2 PF00168.25 EMC81470.1 - 4.1e-12 45.7 0.0 5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain DUF4114 PF13448.1 EMC81470.1 - 0.12 13.1 0.2 0.16 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) Pkinase PF00069.20 EMC81471.1 - 3.2e-67 226.4 0.0 5.5e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81471.1 - 2e-37 128.7 0.0 3.3e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EMC81471.1 - 2.8e-31 106.9 24.0 6.7e-16 57.7 3.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC81471.1 - 4.1e-10 40.0 0.2 8.6e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC81471.1 - 0.0017 17.3 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC81471.1 - 0.0023 17.0 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC81471.1 - 0.072 12.8 0.0 0.27 10.9 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FYVE_2 PF02318.11 EMC81471.1 - 3.4 7.6 15.8 3.2 7.6 2.9 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 EMC81471.1 - 6.1 6.7 14.8 0.11 12.3 2.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon PAS_11 PF14598.1 EMC81472.1 - 4.5e-27 94.2 0.2 8.2e-23 80.4 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EMC81472.1 - 2.3e-25 88.5 0.0 1.6e-19 69.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold HIF-1a_CTAD PF08778.5 EMC81472.1 - 8.7e-21 73.1 0.4 2.2e-20 71.8 0.3 1.8 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.3 EMC81472.1 - 6.8e-19 66.7 0.7 8.6e-18 63.2 0.5 2.5 2 0 0 2 2 2 1 Hypoxia-inducible factor-1 PAS PF00989.19 EMC81472.1 - 3.5e-14 52.5 0.0 2.5e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EMC81472.1 - 5.7e-11 42.7 0.0 1.3e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMC81472.1 - 3.8e-07 30.1 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 EMC81472.1 - 0.091 12.4 0.3 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Ras PF00071.17 EMC81473.1 - 5.7e-27 94.0 0.0 6.6e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81473.1 - 4.3e-06 27.2 0.0 7.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PIG-F PF06699.6 EMC81474.1 - 1.1e-50 172.2 16.5 1.3e-50 172.0 11.5 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F SH PF01445.12 EMC81474.1 - 9.8 5.9 7.1 9.4 5.9 0.9 2.8 1 1 1 2 2 2 0 Viral small hydrophobic protein Cript PF10235.4 EMC81475.1 - 5.8e-33 113.1 6.3 6.6e-33 112.9 4.4 1.0 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.4 EMC81475.1 - 0.041 13.9 5.7 0.057 13.4 4.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Cas_CXXC_CXXC PF09706.5 EMC81475.1 - 0.064 13.4 8.3 0.69 10.1 0.1 2.7 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-ribbon_3 PF13248.1 EMC81475.1 - 0.12 11.6 4.9 3.4 6.9 1.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMC81475.1 - 0.54 9.8 6.6 3 7.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Gin PF10764.4 EMC81475.1 - 0.93 9.2 5.9 3.1 7.6 4.1 1.9 1 1 0 1 1 1 0 Inhibitor of sigma-G Gin zf-BED PF02892.10 EMC81475.1 - 4 7.2 8.7 1.3 8.8 0.3 2.4 1 1 1 2 2 2 0 BED zinc finger Sar8_2 PF03058.9 EMC81475.1 - 4.1 7.7 7.3 7 7.0 5.1 1.5 1 1 0 1 1 1 0 Sar8.2 family zf-H2C2_2 PF13465.1 EMC81476.1 - 1.1e-17 63.3 22.3 8.9e-09 35.2 1.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain DUF3446 PF11928.3 EMC81476.1 - 1.4e-15 57.2 3.6 2.6e-15 56.3 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) zf-C2H2 PF00096.21 EMC81476.1 - 3.4e-15 55.3 17.4 2.9e-05 24.1 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81476.1 - 1.2e-12 47.2 15.7 0.0013 18.9 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC81476.1 - 0.00022 20.8 9.7 0.087 12.5 0.7 3.5 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-BED PF02892.10 EMC81476.1 - 0.0042 16.8 9.5 1.5 8.6 6.7 3.0 1 1 1 2 2 2 1 BED zinc finger zf-C2H2_jaz PF12171.3 EMC81476.1 - 0.032 14.3 5.6 15 5.8 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC81476.1 - 0.069 13.3 6.0 4.3 7.6 0.5 3.6 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC81476.1 - 0.13 12.2 9.8 0.39 10.7 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger RRN7 PF11781.3 EMC81476.1 - 0.39 10.2 6.2 0.44 10.0 0.2 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_2 PF12756.2 EMC81476.1 - 6.7 6.8 7.6 74 3.5 5.2 2.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PDZ PF00595.19 EMC81477.1 - 3.4e-15 55.9 0.1 5.4e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC81477.1 - 1.7e-05 24.6 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain LIM PF00412.17 EMC81477.1 - 2.3e-05 24.3 2.3 3.5e-05 23.7 1.6 1.3 1 0 0 1 1 1 1 LIM domain SH3_1 PF00018.23 EMC81478.1 - 2.5e-16 58.7 0.0 2.4e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC81478.1 - 1.7e-15 56.3 0.1 8.4e-14 50.8 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMC81478.1 - 3.7e-15 55.1 0.1 7.7e-15 54.1 0.0 1.5 2 0 0 2 2 2 1 Variant SH3 domain Metallophos PF00149.23 EMC81479.1 - 1.7e-36 125.4 0.1 3e-36 124.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zip PF02535.17 EMC81481.1 - 1.8e-37 129.0 0.7 2.1e-37 128.8 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.9 EMC81482.1 - 9.1e-36 122.7 4.3 1.1e-35 122.5 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 fn3 PF00041.16 EMC81483.1 - 3.8e-05 23.7 0.1 0.00023 21.2 0.0 2.2 2 1 0 2 2 2 1 Fibronectin type III domain EPTP PF03736.12 EMC81484.1 - 1.2e-80 265.0 16.4 2.9e-13 49.3 0.1 7.7 7 1 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 EMC81484.1 - 1.1e-19 69.9 7.9 1.5e-10 40.6 2.8 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EMC81484.1 - 1.4e-07 30.9 9.9 0.0017 17.9 2.0 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC81484.1 - 1.9e-07 30.8 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC81484.1 - 4.7e-07 28.9 8.0 0.017 15.0 0.4 4.7 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_9 PF14580.1 EMC81484.1 - 0.0011 18.5 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EMC81484.1 - 0.025 14.6 10.6 0.51 10.7 0.6 4.7 4 0 0 4 4 4 0 Leucine rich repeat Pectate_lyase_2 PF06917.7 EMC81484.1 - 0.067 11.4 0.1 0.14 10.3 0.0 1.5 2 0 0 2 2 2 0 Periplasmic pectate lyase DBP10CT PF08147.7 EMC81484.1 - 0.1 12.4 0.5 9.6 6.1 0.1 3.1 3 0 0 3 3 3 0 DBP10CT (NUC160) domain RAI16-like PF10257.4 EMC81485.1 - 1.4e-89 300.4 0.0 1.9e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein PH PF00169.24 EMC81487.1 - 9.6e-06 25.7 0.0 1e-05 25.6 0.0 1.0 1 0 0 1 1 1 1 PH domain FGF PF00167.13 EMC81489.1 - 1.2e-36 125.0 0.8 1.8e-36 124.5 0.5 1.1 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.14 EMC81489.1 - 0.028 13.8 0.0 0.065 12.6 0.0 1.5 1 1 0 1 1 1 0 Interleukin-1 / 18 Fascin PF06268.8 EMC81489.1 - 0.073 13.1 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Polysacc_synt_4 PF04669.8 EMC81490.1 - 1.2e-25 89.9 0.6 1.3e-24 86.6 0.4 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis CRM1_C PF08767.6 EMC81491.1 - 7.1e-05 21.8 0.5 0.00012 21.0 0.4 1.6 1 1 0 1 1 1 1 CRM1 C terminal XPC-binding PF09280.6 EMC81491.1 - 0.25 10.8 4.3 1.7 8.1 0.2 3.5 5 0 0 5 5 5 0 XPC-binding domain IRS PF02174.12 EMC81492.1 - 3.6e-31 106.7 0.1 6.9e-31 105.8 0.1 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) GDNF PF02351.11 EMC81494.1 - 9.4e-15 54.8 0.5 9.4e-15 54.8 0.3 1.5 2 0 0 2 2 2 1 GDNF/GAS1 domain Fez1 PF06818.10 EMC81495.1 - 6.3e-69 232.0 32.2 6.3e-69 232.0 22.3 2.4 2 0 0 2 2 2 1 Fez1 CENP-F_leu_zip PF10473.4 EMC81495.1 - 0.014 15.2 74.5 0.048 13.5 11.3 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EMC81495.1 - 0.019 12.7 57.5 0.0061 14.3 30.5 2.4 1 1 1 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 EMC81495.1 - 0.041 13.0 7.6 0.037 13.2 1.3 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EMC81495.1 - 1 8.2 60.0 1.2 8.0 13.1 3.9 1 1 3 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EMC81495.1 - 1.3 7.5 58.7 0.53 8.8 11.7 4.2 1 1 2 4 4 4 0 Spc7 kinetochore protein ATP-synt_ab PF00006.20 EMC81496.1 - 7.3e-62 208.6 0.0 9.7e-62 208.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC81496.1 - 8.6e-17 61.6 0.0 1.7e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC81496.1 - 3.5e-12 46.3 0.3 8.7e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMC81496.1 - 0.01 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain MFS_1 PF07690.11 EMC81497.1 - 5.1e-40 137.2 49.0 1.2e-32 112.9 26.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 EMC81497.1 - 0.41 9.1 15.8 0.39 9.2 2.6 2.3 2 0 0 2 2 2 0 LacY proton/sugar symporter zf-RING_2 PF13639.1 EMC81498.1 - 1.9e-12 46.7 9.0 4.4e-12 45.6 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC81498.1 - 5.4e-08 32.3 7.8 1.4e-07 31.0 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC81498.1 - 5.8e-08 32.7 8.4 1.4e-07 31.5 5.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC81498.1 - 3.9e-07 29.6 7.5 8.4e-07 28.5 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC81498.1 - 7e-07 29.1 9.2 1.6e-06 28.0 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC81498.1 - 4.8e-06 26.2 7.6 8.7e-06 25.3 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC81498.1 - 0.00026 20.6 1.9 0.00026 20.6 1.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMC81498.1 - 0.00036 20.3 6.3 0.0009 19.0 4.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Endonuclease_7 PF02945.10 EMC81498.1 - 0.095 12.4 1.3 0.13 11.9 0.9 1.2 1 0 0 1 1 1 0 Recombination endonuclease VII Prok-RING_1 PF14446.1 EMC81498.1 - 0.16 11.6 8.9 1.2 8.8 6.2 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EMC81498.1 - 0.32 10.9 9.5 13 5.8 6.6 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EMC81498.1 - 0.52 9.8 4.7 1.1 8.8 3.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Vps39_2 PF10367.4 EMC81498.1 - 1.5 9.0 4.4 1.3 9.1 0.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 ZU5 PF00791.15 EMC81499.1 - 4.1e-27 93.8 0.0 7.6e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 ZU5 domain I-set PF07679.11 EMC81499.1 - 2.2e-12 46.6 0.0 1.5e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC81499.1 - 9.8e-12 44.8 0.0 5.8e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.14 EMC81499.1 - 1.6e-11 44.0 24.5 6.3e-07 29.4 6.6 3.2 2 0 0 2 2 2 2 Thrombospondin type 1 domain Death PF00531.17 EMC81499.1 - 3.1e-11 42.8 0.0 6.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Death domain Ig_3 PF13927.1 EMC81499.1 - 1.6e-05 25.3 0.0 6.3e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC81499.1 - 5.6e-05 23.1 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC81499.1 - 0.0089 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain DUF4573 PF15140.1 EMC81500.1 - 3.1e-07 30.1 14.2 4.6e-06 26.3 9.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) zf-C2H2 PF00096.21 EMC81501.1 - 0.045 14.1 0.3 0.045 14.1 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81501.1 - 0.071 13.4 0.3 0.071 13.4 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Band_7 PF01145.20 EMC81502.1 - 4.9e-14 52.6 1.6 9e-14 51.7 0.2 1.9 1 1 0 2 2 2 1 SPFH domain / Band 7 family DUF4346 PF14251.1 EMC81502.1 - 0.049 13.3 1.3 0.1 12.3 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) RBD-FIP PF09457.5 EMC81503.1 - 1.4e-21 76.0 3.2 1.4e-21 76.0 2.2 2.0 2 0 0 2 2 2 1 FIP domain 7tm_1 PF00001.16 EMC81504.1 - 2.1e-80 269.5 7.5 2.7e-80 269.2 5.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81504.1 - 2.6e-13 49.7 9.7 1.8e-08 33.8 2.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC81504.1 - 2.1e-05 23.8 4.1 2.1e-05 23.8 2.8 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Choline_transpo PF04515.7 EMC81504.1 - 0.034 12.9 10.2 0.32 9.6 1.3 2.5 2 1 0 2 2 2 0 Plasma-membrane choline transporter 7tm_4 PF13853.1 EMC81504.1 - 8.5 6.1 16.2 0.1 12.3 0.7 3.4 4 1 0 4 4 4 0 Olfactory receptor eIF_4EBP PF05456.6 EMC81505.1 - 1.6e-22 79.3 0.1 1.8e-22 79.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TGF_beta PF00019.15 EMC81506.1 - 3.9e-29 101.0 0.9 8.2e-29 99.9 0.6 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC81506.1 - 2.1e-13 50.1 0.0 4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 TGF-beta propeptide SPRY PF00622.23 EMC81507.1 - 2.9e-14 53.2 0.6 8.4e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 SPRY domain START PF01852.14 EMC81508.1 - 9.5e-44 149.1 0.0 1.1e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.15 EMC81508.1 - 0.0073 16.2 0.0 0.021 14.8 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EMC81508.1 - 0.045 13.9 0.1 0.38 10.9 0.0 2.4 2 2 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport AsnA PF03590.10 EMC81508.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Aspartate-ammonia ligase Pigment_DH PF06324.6 EMC81509.1 - 1.6 8.0 3.6 1.8e+02 1.5 0.0 3.8 4 0 0 4 4 4 0 Pigment-dispersing hormone (PDH) Pkinase PF00069.20 EMC81510.1 - 7e-60 202.3 0.0 1.2e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81510.1 - 5.1e-35 120.8 0.0 6.9e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EMC81510.1 - 2.4e-18 66.3 0.0 5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.1 EMC81510.1 - 0.00055 18.9 0.0 0.0009 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC81510.1 - 0.14 11.8 0.1 1 9.0 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family LSM PF01423.17 EMC81511.1 - 0.0014 18.1 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 LSM domain DDHD PF02862.12 EMC81512.1 - 3.5e-51 174.1 0.0 5.3e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 DDHD domain SAM_1 PF00536.25 EMC81512.1 - 6.3e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.15 EMC81512.1 - 2.6e-06 26.7 1.1 0.0075 15.6 0.3 3.0 2 1 1 3 3 3 2 WWE domain SAM_2 PF07647.12 EMC81512.1 - 0.00067 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EMC81512.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 IGR protein motif PAP2 PF01569.16 EMC81513.1 - 6e-14 51.8 0.8 5.1e-13 48.8 0.1 2.0 2 0 0 2 2 2 1 PAP2 superfamily PWWP PF00855.12 EMC81514.1 - 6.1e-38 128.9 16.3 1.1e-22 79.9 1.4 3.4 3 0 0 3 3 3 2 PWWP domain SET PF00856.23 EMC81514.1 - 1.3e-24 87.3 0.4 1.3e-24 87.3 0.3 4.7 2 2 0 2 2 2 1 SET domain PHD PF00628.24 EMC81514.1 - 8.5e-14 50.9 70.6 1.5e-06 27.8 6.1 6.5 4 2 2 6 6 6 4 PHD-finger zf-HC5HC2H PF13771.1 EMC81514.1 - 0.0028 17.7 11.9 0.0028 17.7 8.3 6.1 3 2 2 5 5 5 3 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC81514.1 - 0.0081 16.1 5.1 0.0081 16.1 3.5 6.1 3 2 1 5 5 5 3 PHD-zinc-finger like domain PH PF00169.24 EMC81517.1 - 8.7e-26 90.1 0.1 3.1e-12 46.6 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC81517.1 - 1.4e-14 54.3 0.2 1.3e-05 25.4 0.3 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EMC81517.1 - 1.1e-09 38.2 0.9 0.0014 18.6 0.1 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EMC81517.1 - 6.6e-09 35.9 0.2 0.0051 16.9 0.0 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EMC81517.1 - 8e-05 22.5 0.0 0.0077 16.1 0.0 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Reprolysin PF01421.14 EMC81518.1 - 4.9e-66 222.1 0.0 8.8e-66 221.3 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC81518.1 - 1.9e-38 131.0 5.5 1.9e-38 131.0 3.8 3.5 3 0 0 3 3 1 1 ADAM cysteine-rich Disintegrin PF00200.18 EMC81518.1 - 2.7e-22 78.7 27.7 2.7e-22 78.7 19.2 4.2 4 1 1 5 5 4 1 Disintegrin Reprolysin_5 PF13688.1 EMC81518.1 - 1e-21 77.7 0.2 2.6e-21 76.4 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC81518.1 - 1.5e-19 70.7 0.1 2.6e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 EMC81518.1 - 1.1e-18 67.3 0.8 9.7e-18 64.2 0.6 2.3 1 1 0 1 1 1 1 Reprolysin family propeptide Reprolysin_2 PF13574.1 EMC81518.1 - 1.1e-13 51.6 0.7 2.1e-13 50.6 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC81518.1 - 3.7e-13 49.4 0.1 6.3e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 EMC81518.1 - 0.0024 18.0 12.9 0.0024 18.0 8.9 6.1 5 1 1 6 6 4 1 EGF-like domain Peptidase_M10 PF00413.19 EMC81518.1 - 0.0094 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EMC81518.1 - 0.02 13.7 0.5 0.033 13.0 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.3 EMC81518.1 - 0.037 13.3 1.2 0.065 12.5 0.8 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.8 EMC81518.1 - 0.049 13.2 0.1 0.049 13.2 0.1 2.0 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Reprolysin PF01421.14 EMC81519.1 - 7.5e-52 175.8 0.1 1.7e-51 174.6 0.0 1.6 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC81519.1 - 4.8e-28 97.5 0.5 4.8e-28 97.5 0.4 3.6 3 1 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 EMC81519.1 - 2.4e-27 95.2 0.1 4e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 EMC81519.1 - 1e-16 60.9 22.3 1e-16 60.9 15.5 3.2 3 1 0 3 3 3 1 Disintegrin Reprolysin_5 PF13688.1 EMC81519.1 - 3.4e-07 30.3 0.0 8.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC81519.1 - 3.9e-05 24.1 0.0 6.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EB PF01683.13 EMC81519.1 - 0.00018 21.5 8.9 0.00018 21.5 6.2 5.6 4 1 1 5 5 5 1 EB module EGF_2 PF07974.8 EMC81519.1 - 0.012 15.7 13.9 0.012 15.7 9.7 4.9 5 1 0 5 5 5 0 EGF-like domain ADAM_CR PF08516.7 EMC81520.1 - 2.6e-13 50.0 0.1 2.6e-13 50.0 0.1 2.9 2 1 0 2 2 2 1 ADAM cysteine-rich EGF_2 PF07974.8 EMC81520.1 - 0.00014 21.9 13.2 0.00014 21.9 9.2 2.8 2 1 1 3 3 3 1 EGF-like domain EB PF01683.13 EMC81520.1 - 0.007 16.4 17.7 0.007 16.4 12.3 2.2 2 0 0 2 2 2 1 EB module S_locus_glycop PF00954.15 EMC81520.1 - 0.29 11.4 9.0 0.47 10.7 6.3 1.4 1 1 0 1 1 1 0 S-locus glycoprotein family EGF PF00008.22 EMC81520.1 - 0.31 11.0 20.8 0.058 13.3 8.8 2.7 2 0 0 2 2 2 0 EGF-like domain IDO PF01231.13 EMC81522.1 - 2e-40 138.5 0.0 2.4e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Nif11 PF07862.6 EMC81522.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function TC1 PF15063.1 EMC81523.1 - 2e-39 132.9 0.2 2.4e-39 132.7 0.1 1.1 1 0 0 1 1 1 1 Thyroid cancer protein 1 Toprim_4 PF13662.1 EMC81523.1 - 0.035 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Toprim domain Spore_III_AB PF09548.5 EMC81523.1 - 0.045 13.5 0.4 0.057 13.1 0.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) MgtE_N PF03448.12 EMC81523.1 - 0.085 13.1 1.2 0.65 10.3 0.8 1.9 1 1 0 1 1 1 0 MgtE intracellular N domain zf-met PF12874.2 EMC81524.1 - 4.1e-28 96.6 25.1 8.4e-08 32.1 1.5 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC81524.1 - 7.6e-24 83.2 18.8 1.4e-07 31.4 0.4 4.2 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC81524.1 - 1.4e-07 31.5 12.2 0.021 14.9 2.8 4.0 3 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EMC81524.1 - 2.8e-06 26.7 17.4 0.0027 17.2 0.2 4.2 4 0 0 4 4 4 2 U1 zinc finger zf-C2H2_4 PF13894.1 EMC81524.1 - 4.7e-05 23.4 17.6 0.55 10.6 0.3 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger DUF3449 PF11931.3 EMC81524.1 - 0.13 11.7 8.3 0.27 10.7 0.7 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3449) zf-H2C2_2 PF13465.1 EMC81524.1 - 2.2 8.7 8.8 20 5.7 0.5 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-DBF PF07535.7 EMC81524.1 - 5 6.8 12.3 11 5.8 0.0 3.8 4 0 0 4 4 4 0 DBF zinc finger Fz PF01392.17 EMC81525.1 - 6.8e-32 110.2 3.0 6.8e-32 110.2 2.1 1.7 1 1 1 2 2 2 1 Fz domain NTR PF01759.16 EMC81525.1 - 4.8e-18 64.7 0.4 7.5e-18 64.1 0.2 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module NinG PF05766.7 EMC81525.1 - 0.047 13.4 0.2 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF555 PF04475.7 EMC81525.1 - 0.059 13.3 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Erf4 PF10256.4 EMC81526.1 - 1.4e-21 76.5 0.0 1.5e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3920 PF13058.1 EMC81526.1 - 0.071 12.9 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Acyltransferase PF01553.16 EMC81528.1 - 1.4e-18 66.6 0.1 2.6e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase FTCD_N PF07837.7 EMC81528.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Formiminotransferase domain, N-terminal subdomain Homeobox PF00046.24 EMC81529.1 - 4.8e-22 77.3 1.0 7.3e-22 76.7 0.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC81529.1 - 0.11 11.5 0.1 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Trypsin PF00089.21 EMC81530.1 - 1.2e-66 224.4 0.0 1.9e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 EMC81530.1 - 8.1e-45 150.8 28.3 2.1e-23 82.2 3.1 3.1 3 0 0 3 3 3 2 Kringle domain EGF PF00008.22 EMC81530.1 - 0.0014 18.4 6.2 0.0014 18.4 4.3 4.6 5 1 0 5 5 5 1 EGF-like domain DUF316 PF03761.10 EMC81530.1 - 0.006 15.9 0.1 1.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF316) hEGF PF12661.2 EMC81530.1 - 0.008 16.1 6.3 0.037 14.1 1.4 3.5 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_alliinase PF04863.8 EMC81530.1 - 5.8 6.9 19.2 0.75 9.8 1.1 4.3 4 0 0 4 4 4 0 Alliinase EGF-like domain Pkinase PF00069.20 EMC81531.1 - 3.8e-41 140.9 0.0 8e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81531.1 - 8.7e-27 93.8 0.0 2.2e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.3 EMC81531.1 - 5.8e-19 67.6 5.9 5.8e-19 67.6 4.1 2.6 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain ubiquitin PF00240.18 EMC81531.1 - 7.2e-05 22.1 0.2 0.00021 20.5 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Kdo PF06293.9 EMC81531.1 - 9.6e-05 21.5 0.0 0.00022 20.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC81531.1 - 0.00069 19.4 0.7 0.0031 17.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC81531.1 - 0.0019 17.5 0.1 0.0053 16.1 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL NPV_P10 PF05531.7 EMC81531.1 - 1.5 9.1 5.3 8.6 6.6 0.6 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Porin_3 PF01459.17 EMC81532.1 - 9.8e-74 248.0 7.2 1.1e-73 247.9 5.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DNA_pol_B_palm PF14792.1 EMC81533.1 - 4.1e-41 139.5 0.1 8.2e-41 138.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EMC81533.1 - 1e-21 76.2 0.1 5.6e-21 73.8 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EMC81533.1 - 5e-18 64.5 0.0 9.8e-18 63.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EMC81533.1 - 2.7e-16 59.5 1.2 1e-14 54.4 0.5 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EMC81533.1 - 1.3e-09 38.0 0.2 1.3e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 EMC81533.1 - 0.001 18.6 0.2 1 9.2 0.2 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.2 EMC81533.1 - 0.0025 17.6 0.0 0.72 9.7 0.0 2.7 1 1 1 2 2 2 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.18 EMC81533.1 - 0.0099 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.3 EMC81533.1 - 0.012 15.5 0.0 0.057 13.3 0.0 2.1 1 1 0 1 1 1 0 Pathogenicity locus HHH_3 PF12836.2 EMC81533.1 - 0.046 13.6 0.7 6.5 6.7 0.0 3.3 4 1 0 4 4 4 0 Helix-hairpin-helix motif DUF3701 PF12482.3 EMC81533.1 - 0.11 12.2 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Phage integrase protein Sec7 PF01369.15 EMC81534.1 - 1.1e-38 132.8 0.1 1.6e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.2 EMC81534.1 - 1e-07 31.5 0.6 2.7e-07 30.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC81534.1 - 0.0041 16.7 1.3 0.0076 15.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EMC81534.1 - 0.024 14.6 0.1 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 PRANC domain HLH PF00010.21 EMC81535.1 - 1e-18 66.7 0.6 1e-18 66.7 0.4 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SCRG1 PF15224.1 EMC81537.1 - 1.8e-44 149.3 3.7 2.1e-44 149.1 2.6 1.0 1 0 0 1 1 1 1 Scrapie-responsive protein 1 SAP30_Sin3_bdg PF13867.1 EMC81538.1 - 2.7e-24 84.7 0.0 3.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.1 EMC81538.1 - 3.2e-10 39.5 0.3 5.8e-10 38.6 0.1 1.5 2 0 0 2 2 2 1 SAP30 zinc-finger HMG_box_2 PF09011.5 EMC81539.1 - 7.8e-44 147.9 14.9 3e-27 94.7 4.7 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EMC81539.1 - 1.4e-38 131.0 12.9 8.8e-26 89.9 1.1 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.1 EMC81539.1 - 0.00011 21.8 11.0 0.032 14.0 1.8 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Nucleoplasmin PF03066.10 EMC81539.1 - 0.34 10.4 9.5 0.57 9.6 6.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 EMC81539.1 - 7.8 6.9 25.8 10 6.6 16.9 1.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein Glycos_transf_2 PF00535.21 EMC81540.1 - 1.5e-22 80.0 0.0 2.6e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC81540.1 - 1.9e-21 76.3 1.1 4e-21 75.3 0.8 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC81540.1 - 3.6e-07 30.2 0.0 1.8e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC81540.1 - 4.9e-07 29.1 0.1 1.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC81540.1 - 1.7e-06 27.3 0.0 2.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HCV_NS5a_1b PF08301.8 EMC81540.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b Ricin_B_lectin PF00652.17 EMC81541.1 - 4.3e-23 81.6 0.3 5.9e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.21 EMC81541.1 - 7.1e-16 58.3 0.0 1.5e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 EMC81541.1 - 2.5e-08 33.2 0.2 6.2e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC81541.1 - 0.0003 19.9 0.0 0.0033 16.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 EMC81541.1 - 0.04 14.2 0.0 3 8.2 0.0 2.5 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_3 PF13641.1 EMC81541.1 - 0.046 13.5 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMC81542.1 - 3.8e-08 33.2 0.1 7.3e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sad1_UNC PF07738.8 EMC81544.1 - 1.2e-35 122.2 0.0 1.2e-33 115.7 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Glycos_transf_2 PF00535.21 EMC81545.1 - 8.8e-28 97.0 0.0 1.5e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC81545.1 - 2e-21 76.2 1.7 3.5e-21 75.4 1.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC81545.1 - 7.2e-10 39.0 0.0 2.8e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC81545.1 - 3e-07 29.8 0.1 7.7e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC81545.1 - 6.4e-07 28.7 0.0 1.9e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 EMC81545.1 - 6e-05 23.3 0.0 0.0014 18.9 0.0 2.4 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CBS PF00571.23 EMC81546.1 - 2.8e-37 126.2 2.7 1.8e-10 40.4 0.3 4.2 4 0 0 4 4 4 4 CBS domain Ras PF00071.17 EMC81547.1 - 4.7e-43 146.3 0.4 5.5e-43 146.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81547.1 - 3.4e-13 50.1 0.1 6.4e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC81547.1 - 2.6e-05 23.7 0.1 3.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMC81547.1 - 2.7e-05 23.4 0.1 2.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC81547.1 - 0.0064 16.4 0.1 0.0093 15.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC81547.1 - 0.052 12.7 0.1 0.093 11.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Crystall PF00030.14 EMC81548.1 - 1.1e-57 191.8 3.3 1e-30 105.4 0.3 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EMC81548.1 - 2.7e-06 26.9 0.6 0.17 11.5 0.2 3.8 3 1 1 4 4 4 3 Beta/Gamma crystallin WIYLD PF10440.4 EMC81548.1 - 0.096 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain WD40 PF00400.27 EMC81549.1 - 1.7e-45 151.2 3.0 1.4e-09 37.4 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EMC81549.1 - 8.8e-10 37.3 3.8 0.00024 19.3 0.0 4.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMC81549.1 - 5.4e-06 26.1 0.3 0.77 9.5 0.0 4.0 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EMC81549.1 - 6.6e-05 22.4 0.0 0.41 10.0 0.0 3.6 2 1 2 4 4 4 2 PQQ-like domain PQQ_3 PF13570.1 EMC81549.1 - 0.00061 19.9 0.0 17 5.8 0.0 4.3 3 1 1 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 EMC81549.1 - 0.0019 17.0 3.8 0.19 10.4 0.1 3.6 1 1 3 4 4 4 1 Nup133 N terminal like UBA PF00627.26 EMC81550.1 - 1.4e-23 82.0 0.1 2.1e-07 30.6 0.0 3.8 3 0 0 3 3 3 3 UBA/TS-N domain UBA_4 PF14555.1 EMC81550.1 - 3.3e-05 23.3 0.0 0.18 11.3 0.1 3.4 3 0 0 3 3 3 1 UBA-like domain Rap1_C PF11626.3 EMC81550.1 - 0.00089 19.0 0.1 9.6 6.1 0.0 4.0 4 0 0 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain ubiquitin PF00240.18 EMC81550.1 - 0.0024 17.2 0.7 0.011 15.1 0.6 2.0 2 0 0 2 2 2 1 Ubiquitin family TPR_2 PF07719.12 EMC81550.1 - 0.0073 16.1 8.2 0.76 9.8 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat RuvA_C PF07499.8 EMC81550.1 - 0.015 15.4 0.1 16 5.7 0.0 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain TPR_12 PF13424.1 EMC81550.1 - 0.041 13.8 5.2 8 6.4 0.2 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat BBE PF08031.7 EMC81550.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like UBA_3 PF09288.5 EMC81550.1 - 0.17 11.5 3.7 2.8 7.5 0.0 3.9 5 0 0 5 5 5 0 Fungal ubiquitin-associated domain TPR_1 PF00515.23 EMC81550.1 - 2.8 7.6 6.7 5.6 6.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4641 PF15483.1 EMC81551.1 - 0.023 13.4 2.4 0.033 12.9 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) FGGY_N PF00370.16 EMC81552.1 - 1.2e-20 73.9 0.0 4.5e-15 55.6 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EMC81552.1 - 1.2e-11 44.6 0.0 3.3e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.20 EMC81554.1 - 5.4e-56 189.6 0.0 7.4e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81554.1 - 3.3e-26 91.9 0.0 5.3e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 EMC81554.1 - 2e-11 44.3 13.6 2e-11 44.3 9.4 2.1 2 0 0 2 2 2 1 Activin types I and II receptor domain Endonuclease_NS PF01223.18 EMC81555.1 - 5.4e-53 179.7 0.0 6.6e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Ion_trans PF00520.26 EMC81556.1 - 1e-218 720.2 108.6 4.2e-73 244.8 9.2 5.2 6 0 0 6 6 6 4 Ion transport protein Na_trans_assoc PF06512.8 EMC81556.1 - 1.7e-68 231.1 6.0 1.7e-68 231.1 4.2 2.4 2 0 0 2 2 2 1 Sodium ion transport-associated DUF3451 PF11933.3 EMC81556.1 - 2.4e-40 138.7 4.7 2.4e-40 138.7 3.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3451) PKD_channel PF08016.7 EMC81556.1 - 6.7e-12 44.5 83.6 4.1e-08 32.0 0.3 9.8 6 4 2 9 9 9 8 Polycystin cation channel IQ PF00612.22 EMC81556.1 - 0.0049 16.3 0.9 0.0049 16.3 0.6 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif Ion_trans PF00520.26 EMC81557.1 - 3e-113 375.9 34.3 9e-71 237.2 9.0 3.5 4 0 0 4 4 4 2 Ion transport protein Na_trans_assoc PF06512.8 EMC81557.1 - 7.5e-15 55.5 1.3 7.5e-15 55.5 0.9 2.3 2 0 0 2 2 2 1 Sodium ion transport-associated DUF3451 PF11933.3 EMC81557.1 - 1.5e-08 34.7 9.0 1.5e-08 34.7 6.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3451) PKD_channel PF08016.7 EMC81557.1 - 0.00019 20.0 9.9 0.00019 20.0 6.8 5.5 3 2 1 4 4 4 3 Polycystin cation channel DUF3337 PF11816.3 EMC81558.1 - 3.8e-70 236.9 0.1 5.3e-70 236.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EMC81558.1 - 4.9e-44 146.6 6.3 3.1e-08 33.1 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC81558.1 - 0.0056 15.4 1.5 2.9 6.5 0.2 3.9 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EMC81558.1 - 0.028 12.5 6.2 2.7 5.9 1.0 4.0 1 1 2 4 4 4 0 Nucleoporin Nup120/160 GRASP55_65 PF04495.9 EMC81559.1 - 2.1e-78 261.0 0.1 4.4e-61 204.8 0.0 2.6 2 1 1 3 3 3 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EMC81559.1 - 1.1e-06 28.3 0.0 0.00056 19.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 EMC81559.1 - 0.0012 18.6 0.1 0.094 12.5 0.0 2.8 3 0 0 3 3 3 1 Tricorn protease PDZ domain PAZ_siRNAbind PF12212.3 EMC81559.1 - 0.1 12.2 0.6 0.21 11.2 0.4 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain LIM PF00412.17 EMC81562.1 - 9.2e-09 35.2 11.3 1.1e-08 35.0 7.8 1.1 1 0 0 1 1 1 1 LIM domain Rieske PF00355.21 EMC81562.1 - 0.27 10.8 5.7 0.32 10.5 4.0 1.2 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Dynactin_p62 PF05502.8 EMC81562.1 - 0.41 9.3 4.8 0.45 9.2 3.3 1.0 1 0 0 1 1 1 0 Dynactin p62 family Rad50_zn_hook PF04423.9 EMC81562.1 - 1.8 8.0 5.8 2.8 7.4 4.0 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif OTT_1508_deam PF14441.1 EMC81562.1 - 2.4 7.9 5.6 2.2 8.0 3.9 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase Sugar_tr PF00083.19 EMC81563.1 - 1.7e-31 109.3 10.1 2.2e-31 108.9 7.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC81563.1 - 4.2e-22 78.3 20.8 4.2e-22 78.3 14.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMC81563.1 - 0.00062 18.2 3.0 0.00062 18.2 2.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TPR_10 PF13374.1 EMC81563.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EMC81564.1 - 2.1e-44 151.6 0.0 2.6e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81564.1 - 1.9e-29 102.5 0.0 3.1e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.3 EMC81564.1 - 1e-12 47.4 0.0 1.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C terminal Kinase-like PF14531.1 EMC81564.1 - 0.00025 20.0 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAT1 PF09770.4 EMC81564.1 - 2.2 6.4 8.5 2.6 6.1 5.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 7tm_1 PF00001.16 EMC81565.1 - 1.2e-20 73.7 0.8 1.6e-20 73.3 0.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81565.1 - 0.0048 16.1 1.4 0.0048 16.1 1.0 1.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2975 PF11188.3 EMC81565.1 - 0.0052 16.5 0.8 0.0062 16.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) Clat_adaptor_s PF01217.15 EMC81566.1 - 1.4e-60 203.1 2.2 1.6e-60 202.9 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCCH PF00642.19 EMC81567.1 - 1.9e-12 46.5 12.6 6.3e-07 28.9 2.6 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EMC81567.1 - 3.1e-06 26.9 0.4 9.6e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC81567.1 - 0.0002 20.8 0.0 0.00047 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC81567.1 - 0.00073 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 EMC81567.1 - 0.02 14.8 0.1 0.14 12.1 0.0 2.4 2 1 1 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3430 PF11912.3 EMC81567.1 - 0.092 12.5 0.6 0.14 12.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) DUF1191 PF06697.7 EMC81568.1 - 7e-06 25.0 0.0 8e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4381 PF14316.1 EMC81568.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CcmH PF03918.9 EMC81568.1 - 0.019 13.9 0.0 0.047 12.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3816 PF12822.2 EMC81568.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF2140 PF09911.4 EMC81568.1 - 0.036 13.2 0.3 0.36 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) TMEM171 PF15471.1 EMC81568.1 - 0.043 12.5 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 EphA2_TM PF14575.1 EMC81568.1 - 0.045 14.1 0.5 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.3 EMC81568.1 - 0.06 13.2 0.1 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) INSIG PF07281.7 EMC81568.1 - 0.073 12.4 0.2 0.29 10.4 0.1 1.9 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) DUF4307 PF14155.1 EMC81568.1 - 0.089 12.5 0.2 0.86 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) LRR19-TM PF15176.1 EMC81568.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TMEM154 PF15102.1 EMC81568.1 - 0.32 10.6 3.1 0.12 12.0 0.5 1.6 2 1 0 2 2 2 0 TMEM154 protein family Peptidase_M2 PF01401.13 EMC81569.1 - 6.1e-183 609.2 8.1 5e-182 606.2 5.6 1.9 1 1 0 1 1 1 1 Angiotensin-converting enzyme PDGF PF00341.12 EMC81570.1 - 2.3e-22 78.9 10.0 2.3e-22 78.9 6.9 2.4 2 1 0 2 2 2 1 PDGF/VEGF domain Baculo_p48 PF04878.8 EMC81570.1 - 0.084 11.7 0.5 0.13 11.1 0.4 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein Ank_2 PF12796.2 EMC81572.1 - 4.8e-64 212.7 20.8 4.5e-21 74.9 0.6 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81572.1 - 2.7e-41 137.3 12.9 1.8e-06 27.4 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EMC81572.1 - 1.2e-28 98.9 4.0 1.5e-08 34.9 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81572.1 - 3.5e-28 94.8 8.2 0.00056 19.8 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EMC81572.1 - 4.4e-23 80.7 10.0 1.4e-06 28.3 0.2 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC81572.1 - 2.5e-11 43.2 5.0 4.5e-11 42.4 3.4 1.5 1 0 0 1 1 1 1 SOCS box GCFC PF07842.7 EMC81572.1 - 0.08 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein CRAL_TRIO PF00650.15 EMC81573.1 - 2.7e-29 101.7 0.3 4.4e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.21 EMC81573.1 - 6.1e-21 74.1 0.0 1.6e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.1 EMC81573.1 - 8.1e-08 32.2 0.1 1.8e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Neur_chan_LBD PF02931.18 EMC81575.1 - 5.2e-55 185.9 0.0 6.7e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC81575.1 - 8e-46 156.8 4.2 3e-38 132.0 1.3 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RDD PF06271.7 EMC81575.1 - 0.36 10.7 3.9 0.15 11.9 0.5 1.9 2 0 0 2 2 2 0 RDD family LRR_8 PF13855.1 EMC81577.1 - 6.7e-31 105.8 31.0 2.7e-12 46.2 2.0 5.2 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EMC81577.1 - 6.3e-21 73.5 42.5 4.8e-08 32.4 1.7 7.0 2 2 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC81577.1 - 1.5e-13 48.7 35.5 0.059 13.4 0.3 11.3 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_5 PF13306.1 EMC81577.1 - 1.3e-07 31.3 0.0 0.00034 20.3 0.0 3.7 1 1 3 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC81577.1 - 8.2e-06 25.4 8.7 0.012 15.1 1.8 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRRNT PF01462.13 EMC81577.1 - 0.0013 18.1 3.9 0.0042 16.5 1.8 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EMC81577.1 - 0.002 18.0 35.9 6.2 7.4 0.1 10.8 12 0 0 12 12 12 2 Leucine rich repeat fn3 PF00041.16 EMC81577.1 - 0.0039 17.2 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 EMC81577.1 - 0.017 15.3 0.0 0.056 13.7 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Herpes_gE PF02480.11 EMC81577.1 - 0.053 11.7 0.0 0.078 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Methyltransf_11 PF08241.7 EMC81578.1 - 6.9e-21 74.5 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC81578.1 - 6.7e-15 55.1 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC81578.1 - 4.2e-13 49.1 0.0 6.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC81578.1 - 7e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC81578.1 - 1.5e-11 44.6 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC81578.1 - 3.7e-09 36.0 0.0 6.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EMC81578.1 - 6.1e-06 24.8 0.0 8.3e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 EMC81578.1 - 3.5e-05 24.3 0.0 7.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC81578.1 - 0.00018 20.9 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EMC81578.1 - 0.00081 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EMC81578.1 - 0.002 18.1 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 EMC81578.1 - 0.011 14.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme NodS PF05401.6 EMC81578.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 EMC81578.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_PK PF05891.7 EMC81578.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Keratin_B2_2 PF13885.1 EMC81579.1 - 0.014 15.0 98.7 1.4 8.7 18.7 4.1 1 1 2 3 3 3 0 Keratin, high sulfur B2 protein NUC153 PF08159.7 EMC81580.1 - 6.3e-10 38.4 1.3 6.3e-10 38.4 0.9 3.8 4 0 0 4 4 4 2 NUC153 domain Aminotran_1_2 PF00155.16 EMC81581.1 - 1.9e-55 188.2 0.0 2.5e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMC81581.1 - 8.3e-06 25.1 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMC81581.1 - 0.0032 16.2 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V PHR PF08005.7 EMC81582.1 - 5.2e-45 153.3 0.6 8.8e-45 152.5 0.4 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 EMC81582.1 - 5.3e-24 84.3 0.0 4.1e-23 81.4 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EMC81582.1 - 3.6e-07 29.9 3.2 4.4e-07 29.6 0.8 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch SR-25 PF10500.4 EMC81582.1 - 0.0027 17.1 0.6 0.0041 16.6 0.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein EGF PF00008.22 EMC81583.1 - 2.7e-79 260.5 280.6 1.4e-09 37.7 5.6 19.8 19 1 0 19 19 19 14 EGF-like domain MNNL PF07657.8 EMC81583.1 - 1.7e-30 104.7 2.6 1.7e-30 104.7 1.8 6.5 7 0 0 7 7 7 1 N terminus of Notch ligand DSL PF01414.14 EMC81583.1 - 1.6e-27 95.2 8.3 1.6e-27 95.2 5.7 15.6 14 3 3 17 17 17 2 Delta serrate ligand EGF_2 PF07974.8 EMC81583.1 - 2.1e-25 88.5 326.4 0.00034 20.7 7.4 19.9 19 0 0 19 19 19 15 EGF-like domain hEGF PF12661.2 EMC81583.1 - 2.5e-21 74.2 182.8 0.012 15.5 2.5 19.6 18 0 0 18 18 18 14 Human growth factor-like EGF EGF_CA PF07645.10 EMC81583.1 - 6.6e-07 29.2 25.0 4.5e-05 23.3 6.0 19.5 11 4 11 22 22 22 11 Calcium-binding EGF domain DUF2920 PF11144.3 EMC81583.1 - 0.038 12.9 0.3 0.059 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Cpn60_TCP1 PF00118.19 EMC81584.1 - 1.4e-80 271.2 0.0 1.9e-80 270.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNARE PF05739.14 EMC81585.1 - 5.2e-23 80.5 20.4 7.5e-19 67.1 4.0 2.8 3 0 0 3 3 3 2 SNARE domain SNAP-25 PF00835.14 EMC81585.1 - 8.5e-18 64.8 1.1 1.7e-17 63.9 0.1 2.0 2 0 0 2 2 2 1 SNAP-25 family IncA PF04156.9 EMC81585.1 - 0.052 13.1 4.3 0.19 11.3 1.1 2.1 2 0 0 2 2 2 0 IncA protein MCPsignal PF00015.16 EMC81585.1 - 0.058 12.9 5.1 1.4 8.3 0.2 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec20 PF03908.8 EMC81585.1 - 0.28 10.8 3.6 0.21 11.2 0.4 2.1 2 0 0 2 2 2 0 Sec20 Sec34 PF04136.10 EMC81585.1 - 0.29 10.8 5.2 0.2 11.3 0.5 2.3 2 1 0 2 2 2 0 Sec34-like family V-SNARE_C PF12352.3 EMC81585.1 - 0.37 10.9 11.1 0.065 13.3 0.9 3.7 3 2 1 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus Exonuc_VII_L PF02601.10 EMC81585.1 - 0.39 9.8 6.6 0.99 8.5 4.6 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.6 EMC81585.1 - 0.43 8.0 3.0 5.1 4.4 0.1 2.1 2 0 0 2 2 2 0 Prominin LXG PF04740.7 EMC81585.1 - 0.72 9.6 4.9 0.81 9.4 0.3 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF3450 PF11932.3 EMC81585.1 - 1.4 8.1 11.1 3 7.0 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 EMC81585.1 - 1.5 8.5 7.9 4.8 6.9 0.6 2.7 2 1 0 2 2 2 0 Laminin Domain II HisKA_3 PF07730.8 EMC81585.1 - 1.6 9.1 10.1 2.5 8.5 1.1 3.7 3 1 1 4 4 4 0 Histidine kinase Cytochrom_B562 PF07361.6 EMC81585.1 - 3.2 8.1 9.5 1.7 9.0 2.6 2.6 2 2 0 2 2 2 0 Cytochrome b562 Spore_III_AB PF09548.5 EMC81585.1 - 3.7 7.2 5.5 27 4.4 0.2 2.7 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2120 PF09893.4 EMC81585.1 - 5.1 7.0 6.9 1.5 8.7 0.4 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3359 PF11839.3 EMC81585.1 - 5.4 7.4 7.2 14 6.0 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3359) Phage_Mu_Gam PF07352.7 EMC81585.1 - 5.6 6.4 7.8 0.48 9.9 0.3 2.6 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Ank_2 PF12796.2 EMC81586.1 - 1.6e-66 220.6 6.4 2.1e-20 72.8 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81586.1 - 1.2e-58 192.1 9.7 2.4e-09 36.5 0.0 10.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 EMC81586.1 - 3.5e-50 166.8 9.7 1.5e-11 44.1 0.1 8.9 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81586.1 - 1.8e-45 148.3 7.2 3.8e-07 29.7 0.0 11.1 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.1 EMC81586.1 - 1.9e-44 149.2 8.2 5.1e-15 55.5 0.0 7.3 5 1 3 8 8 8 7 Ankyrin repeats (many copies) adh_short PF00106.20 EMC81587.1 - 4.1e-10 39.8 0.0 9.4e-10 38.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 EMC81587.1 - 5.7e-06 25.6 0.0 6.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 EMC81587.1 - 5.7e-05 22.9 0.0 6.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HMG_box PF00505.14 EMC81587.1 - 0.002 18.3 0.9 0.0038 17.4 0.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box Borrelia_P83 PF05262.6 EMC81591.1 - 1.3 7.1 42.1 2.1 6.5 29.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4581 PF15167.1 EMC81592.1 - 7.2e-54 181.0 1.0 7.9e-54 180.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) Toxin_27 PF08099.6 EMC81592.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Scorpion calcine family EAF PF09816.4 EMC81593.1 - 3.8e-20 71.8 0.0 1.1e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor TFIIIC_delta PF12657.2 EMC81593.1 - 0.014 15.1 1.4 0.022 14.4 0.0 1.9 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term DUF1117 PF06547.7 EMC81593.1 - 0.071 13.2 0.3 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Macoilin PF09726.4 EMC81593.1 - 0.59 8.3 6.7 0.68 8.1 4.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_12 PF08242.7 EMC81594.1 - 3.4e-16 59.5 0.1 2.5e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC81594.1 - 6.7e-14 51.9 0.1 1.2e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC81594.1 - 7.7e-12 45.7 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC81594.1 - 4e-11 42.7 0.1 5.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC81594.1 - 8.8e-10 38.9 0.2 3.6e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC81594.1 - 6.2e-08 32.9 0.1 1.7e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC81594.1 - 7.7e-08 32.3 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EMC81594.1 - 2.9e-05 23.5 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EMC81594.1 - 0.00032 20.1 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EMC81594.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 EMC81594.1 - 0.011 15.0 0.6 2.4 7.4 0.0 2.5 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain TrkA_N PF02254.13 EMC81594.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain FtsL PF04999.8 EMC81594.1 - 0.59 9.8 2.3 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Cell division protein FtsL SH3BP5 PF05276.9 EMC81595.1 - 2.9e-111 370.5 20.0 4.4e-111 369.9 13.9 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF2321 PF10083.4 EMC81595.1 - 6.3 6.2 6.2 8.5 5.8 0.7 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Calpain_III PF01067.17 EMC81596.1 - 3.1e-24 85.2 0.2 3.2e-16 59.2 0.0 2.5 2 1 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 EMC81597.1 - 1.8e-24 86.2 0.1 2.1e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.13 EMC81597.1 - 9.6e-17 60.6 5.9 3.1e-14 52.6 1.6 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EMC81597.1 - 0.068 12.8 0.4 0.068 12.8 0.3 2.0 2 0 0 2 2 2 0 TPR repeat LPP PF04728.8 EMC81597.1 - 0.081 12.7 2.0 0.18 11.6 0.0 2.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper T2SF PF00482.18 EMC81597.1 - 0.16 11.8 1.8 0.22 11.4 0.2 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Asp-B-Hydro_N PF05279.6 EMC81597.1 - 0.38 10.5 5.4 0.54 10.0 3.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TPR_2 PF07719.12 EMC81597.1 - 0.49 10.4 2.5 0.49 10.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PRCC PF10253.4 EMC81597.1 - 2.8 8.5 9.4 7.1 7.2 6.6 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ISG65-75 PF11727.3 EMC81597.1 - 3 6.7 9.6 0.2 10.6 1.0 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein VSG_B PF13206.1 EMC81597.1 - 3.3 6.7 9.9 7 5.6 6.9 1.4 1 1 0 1 1 1 0 Trypanosomal VSG domain CUB PF00431.15 EMC81598.1 - 2.3e-05 24.4 0.0 2.7 8.1 0.0 4.3 4 0 0 4 4 4 2 CUB domain Shisa PF13908.1 EMC81598.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 EMC81598.1 - 0.28 11.3 4.4 9.1 6.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Lectin_C PF00059.16 EMC81599.1 - 5.4e-17 62.3 0.1 8e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain DUF333 PF03891.10 EMC81599.1 - 0.00047 19.9 0.7 0.095 12.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF333) Chordopox_A33R PF05966.7 EMC81599.1 - 0.0033 16.2 0.1 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 Chordopoxvirus A33R protein DUF167 PF02594.11 EMC81599.1 - 0.13 12.2 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 RNase_PH PF01138.16 EMC81600.1 - 7.6e-24 84.5 0.0 1.2e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMC81600.1 - 4.9e-09 36.0 0.1 1.2e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-DHHC PF01529.15 EMC81601.1 - 7.5e-40 136.1 10.0 7.5e-40 136.1 6.9 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_N PF00868.15 EMC81602.1 - 8e-31 106.5 0.0 2.5e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.17 EMC81602.1 - 1.2e-19 70.2 0.2 2e-13 50.2 0.0 2.7 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 EMC81602.1 - 7.6e-16 58.3 0.1 1.6e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4604 PF15377.1 EMC81603.1 - 1.5e-38 132.4 15.7 1.7e-38 132.2 10.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Asp-B-Hydro_N PF05279.6 EMC81603.1 - 0.065 13.0 8.4 0.081 12.7 5.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Arm PF00514.18 EMC81606.1 - 6.6e-49 162.1 19.1 2.2e-08 33.5 0.1 12.4 13 0 0 13 13 13 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC81606.1 - 6.6e-14 51.9 7.4 7.2e-06 26.1 0.2 4.7 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EMC81606.1 - 1.5e-06 27.7 2.5 3.2 8.0 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.15 EMC81606.1 - 8.1e-06 24.4 3.0 0.0034 15.7 0.7 3.2 3 0 0 3 3 3 2 Adaptin N terminal region KAP PF05804.7 EMC81606.1 - 0.00032 18.7 0.4 0.027 12.3 0.0 3.2 3 1 1 4 4 4 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EMC81606.1 - 0.00097 18.3 2.2 0.19 10.8 0.0 3.7 3 1 0 3 3 3 1 Armadillo-like Cnd1 PF12717.2 EMC81606.1 - 0.0062 16.4 0.5 0.2 11.4 0.1 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EMC81606.1 - 0.036 14.5 12.6 1.9 9.0 0.1 6.0 6 2 2 8 8 8 0 HEAT-like repeat RasGEF_N_2 PF14663.1 EMC81606.1 - 0.041 13.8 4.8 6.1 6.8 0.1 3.9 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ric8 PF10165.4 EMC81607.1 - 0.13 11.0 5.9 0.26 10.0 2.6 2.0 1 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn TAN PF11640.3 EMC81607.1 - 0.14 11.9 2.3 18 5.0 0.4 3.1 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair SAPS PF04499.10 EMC81607.1 - 0.27 9.8 4.3 0.34 9.5 0.1 2.1 1 1 1 2 2 2 0 SIT4 phosphatase-associated protein HEAT_2 PF13646.1 EMC81608.1 - 2.9e-05 24.2 0.2 0.023 14.9 0.0 3.5 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EMC81608.1 - 0.0016 18.3 0.4 20 5.6 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat DUF3385 PF11865.3 EMC81608.1 - 0.076 12.9 4.5 0.29 11.0 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) RICTOR_V PF14668.1 EMC81608.1 - 0.14 12.1 2.0 6.9 6.6 0.1 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HAP1_N PF04849.8 EMC81609.1 - 5.7e-143 475.4 35.6 8.3e-143 474.9 24.7 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.3 EMC81609.1 - 5.6e-68 228.2 24.7 6.2e-43 146.8 4.6 3.4 4 0 0 4 4 4 2 Kinesin associated protein DUF1664 PF07889.7 EMC81609.1 - 0.057 13.2 16.6 0.046 13.5 1.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 EMC81609.1 - 0.081 12.4 9.1 4 6.9 3.8 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mod_r PF07200.8 EMC81609.1 - 0.61 9.9 31.9 0.11 12.3 6.7 3.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EMC81609.1 - 2.6 7.6 43.4 9.4 5.7 14.1 3.3 1 1 2 3 3 3 0 IncA protein DUF4226 PF10774.4 EMC81609.1 - 3.1 7.8 9.3 0.23 11.4 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) Atg14 PF10186.4 EMC81609.1 - 5.3 5.8 31.4 3.2 6.6 2.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EMC81609.1 - 5.6 7.3 32.2 19 5.6 2.6 4.5 1 1 2 4 4 4 0 Protein of unknown function (DUF972) TUDOR PF00567.19 EMC81610.1 - 2.7e-20 72.4 0.3 8.7e-20 70.7 0.2 2.0 1 0 0 1 1 1 1 Tudor domain Pkinase PF00069.20 EMC81610.1 - 3.7e-19 68.8 0.0 1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81610.1 - 1.4e-12 47.2 0.0 2.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SMN PF06003.7 EMC81610.1 - 0.0025 16.9 0.0 0.0067 15.5 0.0 1.7 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) SNase PF00565.12 EMC81610.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF4463 PF14703.1 EMC81610.1 - 0.078 13.5 0.1 0.078 13.5 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4463) DUF4525 PF15027.1 EMC81611.1 - 7e-74 245.9 0.3 7.8e-74 245.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF2897 PF11446.3 EMC81611.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RRM_1 PF00076.17 EMC81612.1 - 3.9e-20 71.2 0.0 5.5e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC81612.1 - 1.2e-15 57.2 0.0 1.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC81612.1 - 1.1e-09 37.9 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EMC81612.1 - 0.64 9.7 56.1 0.1 12.3 25.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Zip PF02535.17 EMC81612.1 - 3 6.7 9.2 3.8 6.4 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter KH_1 PF00013.24 EMC81613.1 - 5.7e-56 186.0 12.7 2.5e-14 52.6 0.1 4.7 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 EMC81613.1 - 5.7e-38 127.9 12.6 4.9e-09 35.6 0.0 4.8 4 0 0 4 4 4 4 KH domain RRM_1 PF00076.17 EMC81613.1 - 8.3e-17 60.5 0.0 9.3e-09 34.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.12 EMC81613.1 - 4.7e-16 58.1 6.4 0.0018 17.8 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 EMC81613.1 - 1.1e-14 53.7 0.5 0.0012 18.4 0.0 4.7 4 0 0 4 4 4 4 KH domain RRM_6 PF14259.1 EMC81613.1 - 2.9e-14 52.7 0.0 1.1e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC81613.1 - 4.6e-10 39.1 0.1 7.1e-07 28.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.1 EMC81613.1 - 3.4e-08 33.1 2.6 0.24 11.2 0.1 4.5 4 0 0 4 4 4 3 NusA-like KH domain SLS PF14611.1 EMC81613.1 - 0.035 13.5 7.7 2.7 7.3 0.0 3.5 3 1 1 4 4 4 0 Mitochondrial inner-membrane-bound regulator DUF4041 PF13250.1 EMC81613.1 - 0.12 11.9 1.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Evr1_Alr PF04777.8 EMC81613.1 - 0.16 11.8 0.1 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Erv1 / Alr family LcrG PF07216.7 EMC81613.1 - 0.18 11.8 3.0 1.9 8.5 0.8 2.6 2 0 0 2 2 2 0 LcrG protein Oligomerisation PF02410.10 EMC81614.1 - 2.7e-19 69.0 0.2 3.8e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 Oligomerisation domain Mlo PF03094.10 EMC81614.1 - 0.012 13.8 0.2 0.014 13.5 0.1 1.0 1 0 0 1 1 1 0 Mlo family Herpes_glycop_D PF01537.12 EMC81615.1 - 0.059 13.3 0.3 0.089 12.7 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain Kelch_1 PF01344.20 EMC81618.1 - 1.4e-44 149.4 12.7 8.8e-14 50.7 0.3 5.7 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 EMC81618.1 - 4.2e-34 116.4 1.0 4.9e-33 113.0 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 EMC81618.1 - 1.1e-30 104.5 8.9 1.1e-09 38.0 0.0 6.4 1 1 5 6 6 6 4 Kelch motif BTB PF00651.26 EMC81618.1 - 5.2e-29 100.4 1.2 5.2e-29 100.4 0.8 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 EMC81618.1 - 6.2e-26 89.9 0.9 5e-08 32.5 0.0 6.3 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC81618.1 - 1e-21 75.7 6.1 1.2e-06 27.9 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 EMC81618.1 - 5.8e-18 64.5 1.1 1.4e-05 25.1 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC81618.1 - 6.6e-11 41.9 2.6 0.0026 17.6 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.6 EMC81618.1 - 0.0017 17.4 1.7 0.0045 16.0 0.1 2.3 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus UvrD-helicase PF00580.16 EMC81618.1 - 0.086 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Hyccin PF09790.4 EMC81619.1 - 2.3e-137 456.9 1.2 3.5e-137 456.3 0.8 1.3 1 0 0 1 1 1 1 Hyccin IL6 PF00489.12 EMC81620.1 - 1.9e-43 147.7 0.5 2.1e-43 147.5 0.4 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family SAM_decarbox PF01536.11 EMC81620.1 - 0.0094 14.6 0.1 0.01 14.5 0.1 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Tropomodulin PF03250.9 EMC81620.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 Tropomodulin RasGEF PF00617.14 EMC81621.1 - 2.2e-63 213.4 2.3 4.9e-63 212.2 1.6 1.6 1 0 0 1 1 1 1 RasGEF domain DEP PF00610.16 EMC81621.1 - 1.8e-15 56.4 0.1 4.7e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.15 EMC81621.1 - 4.3e-12 46.0 1.4 4.3e-12 46.0 1.0 2.4 3 0 0 3 3 3 1 RasGEF N-terminal motif RA PF00788.18 EMC81621.1 - 0.0005 20.5 0.1 0.0016 18.8 0.1 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Gp58 PF07902.6 EMC81621.1 - 0.038 12.2 0.0 0.064 11.4 0.0 1.2 1 0 0 1 1 1 0 gp58-like protein zf-4CXXC_R1 PF10497.4 EMC81622.1 - 1.2e-39 134.6 10.7 2.2e-39 133.7 7.4 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 CTC1 PF15489.1 EMC81622.1 - 0.087 10.1 2.5 0.13 9.5 1.7 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 AAA_9 PF12781.2 EMC81623.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region D5 AAA_7 PF12775.2 EMC81624.1 - 9.8e-18 64.1 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_25 PF13481.1 EMC81624.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.2 EMC81625.1 - 4.4e-15 55.8 0.2 4.8e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 zf-H2C2_2 PF13465.1 EMC81626.1 - 1.9e-14 53.1 8.7 1.3e-08 34.7 2.0 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC81626.1 - 5.3e-11 42.1 30.7 1.3e-05 25.2 0.7 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81626.1 - 5.9e-10 38.7 18.9 0.00064 19.8 1.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC81626.1 - 0.02 14.8 10.3 0.62 10.0 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC81626.1 - 0.053 13.6 6.3 4.3 7.5 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RRF PF01765.14 EMC81626.1 - 2.8 7.4 6.4 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 Ribosome recycling factor Zn_Tnp_IS1 PF03811.8 EMC81626.1 - 3.8 7.0 8.5 6.2 6.4 1.5 2.8 2 0 0 2 2 2 0 InsA N-terminal domain ABC_membrane PF00664.18 EMC81627.1 - 8.1e-123 409.2 38.4 5.7e-69 232.5 12.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC81627.1 - 7e-73 243.3 4.9 1.8e-37 128.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EMC81627.1 - 6.8e-18 64.7 0.0 2.2e-07 30.3 0.0 3.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC81627.1 - 6.2e-10 39.3 2.9 0.00071 19.6 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EMC81627.1 - 6.7e-10 38.1 3.5 4.4e-05 22.2 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 EMC81627.1 - 2.9e-09 37.3 0.7 0.16 11.8 0.0 4.7 3 2 1 4 4 3 3 AAA domain AAA_22 PF13401.1 EMC81627.1 - 2.7e-08 34.0 2.1 0.0081 16.3 0.1 3.3 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMC81627.1 - 1e-06 28.0 0.0 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC81627.1 - 5.7e-06 27.1 0.1 0.012 16.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EMC81627.1 - 8.2e-06 25.2 1.8 0.064 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMC81627.1 - 1.5e-05 24.7 2.4 0.22 11.4 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EMC81627.1 - 2e-05 24.6 0.4 0.14 12.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.10 EMC81627.1 - 4.1e-05 22.4 0.0 0.2 10.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EMC81627.1 - 0.0001 22.0 0.1 0.48 10.1 0.0 3.7 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.24 EMC81627.1 - 0.00022 21.4 5.3 0.36 11.0 0.6 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMC81627.1 - 0.00043 20.1 0.1 0.84 9.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 EMC81627.1 - 0.0023 17.4 1.6 17 4.7 0.0 4.0 4 0 0 4 4 4 0 AAA-like domain AAA_25 PF13481.1 EMC81627.1 - 0.0026 17.1 2.0 1.1 8.5 0.4 3.2 3 1 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EMC81627.1 - 0.0031 17.0 0.1 3 7.2 0.0 2.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EMC81627.1 - 0.0036 17.5 3.3 0.73 10.1 0.0 3.8 4 1 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 EMC81627.1 - 0.011 15.8 0.0 3.5 7.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase PRK PF00485.13 EMC81627.1 - 0.012 15.1 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 EMC81627.1 - 0.027 13.6 0.0 2.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EMC81627.1 - 0.032 13.7 0.0 9.5 5.6 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EMC81627.1 - 0.037 13.9 0.4 5.9 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EMC81627.1 - 0.038 13.0 3.4 1.1 8.2 0.0 3.6 4 0 0 4 4 4 0 Zeta toxin Miro PF08477.8 EMC81627.1 - 0.069 13.6 0.0 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EMC81627.1 - 0.08 12.6 0.2 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.15 EMC81627.1 - 0.14 10.8 10.1 0.19 10.4 0.0 3.0 3 0 0 3 3 2 0 G-protein alpha subunit DUF87 PF01935.12 EMC81627.1 - 0.67 9.7 6.1 1.5 8.6 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 Integrin_beta PF00362.13 EMC81628.1 - 1.9e-146 488.3 0.2 1.9e-146 488.3 0.2 1.9 2 0 0 2 2 2 1 Integrin, beta chain EGF_2 PF07974.8 EMC81628.1 - 7.1e-07 29.2 55.1 0.00013 22.0 9.1 5.5 5 0 0 5 5 5 3 EGF-like domain Death PF00531.17 EMC81629.1 - 8.3e-06 25.4 1.6 0.13 12.0 0.0 3.0 1 1 2 3 3 3 2 Death domain SH3_2 PF07653.12 EMC81629.1 - 0.00013 21.3 0.1 0.00025 20.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain ZU5 PF00791.15 EMC81629.1 - 0.0016 18.0 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain DUF1446 PF07287.6 EMC81629.1 - 0.095 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) Chs3p PF12271.3 EMC81630.1 - 0.0049 15.8 0.9 0.0072 15.3 0.6 1.3 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ABC_membrane_3 PF13748.1 EMC81630.1 - 0.098 11.6 0.6 0.21 10.5 0.4 1.6 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF3815 PF12821.2 EMC81630.1 - 0.11 12.4 3.0 0.17 11.8 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3815) DUF4131 PF13567.1 EMC81630.1 - 4.2 6.7 7.2 0.6 9.5 2.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SHS2_Rpb7-N PF03876.12 EMC81631.1 - 1.6e-10 40.9 0.0 3.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMC81631.1 - 0.068 13.2 0.0 0.2 11.7 0.0 1.9 1 1 0 1 1 1 0 S1 RNA binding domain HLH PF00010.21 EMC81632.1 - 3.4e-17 61.8 0.7 3.4e-17 61.8 0.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Dor1 PF04124.7 EMC81632.1 - 0.08 11.3 0.4 0.11 11.0 0.3 1.1 1 0 0 1 1 1 0 Dor1-like family Hist_deacetyl PF00850.14 EMC81633.1 - 6.3e-90 301.6 0.0 6.3e-90 301.6 0.0 2.1 3 0 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.3 EMC81633.1 - 5.2e-38 128.9 47.0 5.2e-38 128.9 32.6 4.2 5 0 0 5 5 5 1 Glutamine rich N terminal domain of histone deacetylase 4 PXA PF02194.10 EMC81634.1 - 6.1e-58 195.4 0.7 1.2e-57 194.4 0.1 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EMC81634.1 - 2.4e-27 95.2 0.5 4.9e-21 74.9 0.0 4.3 3 1 1 4 4 4 2 Sorting nexin C terminal PX PF00787.19 EMC81634.1 - 3.8e-23 81.4 0.3 3.8e-23 81.4 0.2 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EMC81634.1 - 5.5e-21 74.8 4.2 1.6e-19 70.1 0.1 3.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain COX5A PF02284.11 EMC81634.1 - 0.025 14.5 0.2 0.69 9.8 0.0 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va BLOC1_2 PF10046.4 EMC81634.1 - 0.065 13.3 1.7 0.21 11.7 0.2 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAS_3 PF08447.6 EMC81635.1 - 1.6e-17 63.3 0.1 1.4e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 EMC81635.1 - 9.5e-14 51.2 3.1 7e-10 38.8 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 EMC81635.1 - 1.1e-12 47.7 2.9 1.1e-11 44.4 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 EMC81635.1 - 1.5e-06 28.4 0.1 0.063 13.6 0.0 2.9 3 0 0 3 3 3 2 PAS domain HLH PF00010.21 EMC81635.1 - 2.2e-05 24.0 0.2 4.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.5 EMC81635.1 - 0.0093 15.9 2.3 0.075 13.0 0.0 2.7 3 0 0 3 3 3 1 PAS fold Thioredoxin_7 PF13899.1 EMC81636.1 - 2.2e-26 91.6 0.3 4.2e-26 90.7 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredox_DsbH PF03190.10 EMC81636.1 - 2.1e-06 27.5 0.1 3.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 EMC81636.1 - 2.4e-05 24.4 0.4 6.7e-05 23.0 0.3 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC81637.1 - 3.1e-25 88.0 0.0 5.6e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC81637.1 - 0.091 12.9 0.1 0.44 10.7 0.0 2.1 2 1 0 2 2 2 0 Thioredoxin-like domain Tetraspannin PF00335.15 EMC81638.1 - 3.9e-21 75.3 13.3 5e-21 74.9 9.2 1.1 1 0 0 1 1 1 1 Tetraspanin family MIG-14_Wnt-bd PF06664.7 EMC81638.1 - 0.048 12.4 2.5 0.077 11.8 1.7 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion CcoS PF03597.10 EMC81638.1 - 0.051 13.0 1.6 0.051 13.0 1.1 3.3 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type GAPT PF11770.3 EMC81638.1 - 0.64 9.6 4.1 0.24 11.0 0.9 1.7 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) DUF843 PF05814.6 EMC81638.1 - 2.8 7.7 8.6 8.3 6.2 5.9 1.7 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) W2 PF02020.13 EMC81639.1 - 2.1e-23 82.0 4.0 2.1e-23 82.0 2.7 3.0 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DIL PF01843.14 EMC81639.1 - 0.0056 16.5 5.2 7.5 6.4 0.1 4.4 4 1 1 5 5 5 2 DIL domain Ank_2 PF12796.2 EMC81640.1 - 4.9e-17 62.0 1.1 9.1e-16 57.9 0.2 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81640.1 - 1.3e-16 59.4 1.3 3.2e-09 36.1 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMC81640.1 - 5.2e-15 55.1 0.5 4.7e-09 36.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC81640.1 - 1.6e-14 53.9 0.5 6.3e-08 32.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81640.1 - 3.2e-13 48.4 1.8 1.6e-08 33.9 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat zf-MYND PF01753.13 EMC81640.1 - 1.6e-09 37.4 13.3 1.6e-09 37.4 9.2 2.3 2 0 0 2 2 2 1 MYND finger CMV_1a PF12467.3 EMC81640.1 - 0.4 11.0 5.8 0.67 10.3 4.0 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family TraV PF09676.5 EMC81640.1 - 0.43 11.2 4.0 0.79 10.4 2.8 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) zf-Mss51 PF13824.1 EMC81640.1 - 0.5 10.2 6.3 1.5 8.7 4.4 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ATP-synt_E PF05680.7 EMC81640.1 - 2.1 8.3 6.7 3.7 7.5 4.7 1.5 1 0 0 1 1 1 0 ATP synthase E chain LRR_4 PF12799.2 EMC81641.1 - 1.7e-14 53.0 11.0 1.1e-05 24.9 0.4 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EMC81641.1 - 1.7e-13 50.5 3.4 1.5e-11 44.1 0.7 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 EMC81641.1 - 3.2e-08 33.2 11.1 3.9e-06 26.5 4.0 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMC81641.1 - 4.6e-06 25.9 11.3 0.096 12.7 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC81641.1 - 0.00012 21.7 11.6 0.13 12.5 0.3 5.3 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EMC81641.1 - 0.056 13.5 8.3 0.88 9.8 1.0 3.9 3 1 0 3 3 3 0 Leucine Rich repeat Sclerostin PF05463.6 EMC81642.1 - 6.3e-101 335.8 5.9 7.1e-101 335.7 4.1 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) Cys_knot PF00007.17 EMC81642.1 - 3.5e-05 23.8 7.6 0.00018 21.5 5.3 1.9 1 1 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 EMC81642.1 - 5.4e-05 22.6 1.6 9.6e-05 21.7 1.1 1.4 1 0 0 1 1 1 1 DAN domain DUF977 PF06163.6 EMC81642.1 - 0.053 13.2 0.4 0.095 12.4 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DUF3362 PF11842.3 EMC81644.1 - 0.046 13.6 0.6 0.055 13.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) MutS_V PF00488.16 EMC81646.1 - 1e-84 283.6 0.2 1.8e-84 282.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC81646.1 - 2.3e-32 112.4 2.4 2.7e-32 112.2 0.3 2.1 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.12 EMC81646.1 - 1.4e-19 70.5 0.2 3.3e-19 69.3 0.2 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EMC81646.1 - 1.9e-16 60.0 0.0 4.2e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 EMC81646.1 - 4.5e-05 23.3 1.0 0.001 18.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC81646.1 - 0.006 15.9 0.0 0.41 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC81646.1 - 0.0073 16.4 0.7 0.062 13.4 0.0 2.9 3 1 1 4 4 4 1 AAA domain AAA_30 PF13604.1 EMC81646.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC81646.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EMC81646.1 - 0.13 11.9 3.3 0.46 10.1 0.3 2.9 2 1 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EMC81646.1 - 0.24 11.7 3.4 0.14 12.4 0.5 2.1 2 1 0 2 2 2 0 AAA domain Glyco_transf_8 PF01501.15 EMC81647.1 - 7.7e-38 130.2 0.0 1.2e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EMC81647.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 EMC81647.1 - 0.016 14.9 0.1 0.036 13.8 0.1 1.6 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase SNF2_N PF00176.18 EMC81648.1 - 6.6e-83 277.9 0.0 8.8e-83 277.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EMC81648.1 - 1.5e-17 63.4 0.0 2.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EMC81648.1 - 5.6e-12 45.3 0.0 1.6e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EMC81648.1 - 1.6e-08 34.2 11.5 4.7e-08 32.7 8.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC81648.1 - 6.9e-08 32.0 10.1 2e-07 30.5 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC81648.1 - 1.2e-07 31.6 13.3 3.6e-07 30.1 9.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC81648.1 - 1.3e-07 31.1 12.0 3.4e-07 29.8 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC81648.1 - 1.9e-05 24.2 11.3 1.9e-05 24.2 7.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC81648.1 - 4e-05 23.3 1.5 0.00011 21.9 1.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMC81648.1 - 5e-05 23.3 3.5 0.00015 21.8 2.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC81648.1 - 0.00013 21.7 12.9 0.00031 20.5 9.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC81648.1 - 0.0035 17.0 8.9 0.0088 15.7 6.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger HDA2-3 PF11496.3 EMC81648.1 - 0.033 12.9 0.0 0.64 8.7 0.0 2.7 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_6 PF14835.1 EMC81648.1 - 0.19 11.5 5.2 0.57 10.0 3.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Tubulin PF00091.20 EMC81649.1 - 1.3e-69 234.3 0.0 1.7e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC81649.1 - 8.5e-52 174.4 0.0 1.3e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC81649.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Cu-oxidase_3 PF07732.10 EMC81650.1 - 1.2e-29 102.4 1.1 9.5e-10 38.2 0.0 5.9 5 0 0 5 5 5 5 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC81650.1 - 7.7e-29 99.9 12.0 9.7e-16 57.5 2.1 6.0 6 0 0 6 6 6 4 Multicopper oxidase Cu-oxidase PF00394.17 EMC81650.1 - 9.9e-13 48.2 0.2 1.3e-06 28.4 0.0 2.8 2 0 0 2 2 2 2 Multicopper oxidase DUF4585 PF15232.1 EMC81651.1 - 3.9e-19 68.2 0.1 0.55 10.1 0.0 7.9 1 1 9 10 10 10 10 Domain of unknown function (DUF4585) Oest_recep PF02159.10 EMC81651.1 - 1.8 8.6 63.7 20 5.2 2.4 7.6 1 1 5 6 6 6 0 Oestrogen receptor L6_membrane PF05805.7 EMC81652.1 - 1e-55 188.3 17.7 1.2e-55 188.1 12.3 1.0 1 0 0 1 1 1 1 L6 membrane protein DUF1616 PF07760.6 EMC81652.1 - 4 6.4 6.3 0.37 9.8 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) L6_membrane PF05805.7 EMC81653.1 - 1e-72 243.8 14.5 1.1e-72 243.6 10.0 1.0 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.12 EMC81653.1 - 0.0077 15.7 1.5 0.0077 15.7 1.0 2.2 2 0 0 2 2 2 1 Yip1 domain ABC2_membrane_4 PF12730.2 EMC81653.1 - 0.53 9.3 7.0 0.79 8.8 0.0 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein Cation_efflux PF01545.16 EMC81653.1 - 0.79 8.7 4.3 0.14 11.2 0.4 1.6 2 0 0 2 2 2 0 Cation efflux family DUF1418 PF07214.7 EMC81653.1 - 1.9 8.1 4.8 27 4.4 3.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1418) DUF2975 PF11188.3 EMC81653.1 - 3 7.5 7.5 1.1 8.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) L6_membrane PF05805.7 EMC81654.1 - 5.6e-75 251.1 18.9 7.6e-75 250.7 13.1 1.2 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.12 EMC81654.1 - 2 7.8 7.9 8.6 5.8 5.4 2.2 1 1 0 1 1 1 0 Yip1 domain Tic20 PF09685.5 EMC81654.1 - 6.3 6.8 8.8 2.3 8.2 2.4 2.6 2 1 0 2 2 2 0 Tic20-like protein HCaRG PF07258.9 EMC81659.1 - 2.6e-29 102.0 1.7 3e-29 101.8 1.2 1.0 1 0 0 1 1 1 1 HCaRG protein HTH_1 PF00126.22 EMC81659.1 - 0.0012 18.5 0.5 0.039 13.6 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family SOCS PF12610.3 EMC81659.1 - 0.063 13.6 0.4 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Suppressor of cytokine signalling Fzo_mitofusin PF04799.8 EMC81659.1 - 0.15 11.4 0.8 0.24 10.7 0.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region zf-RING_2 PF13639.1 EMC81660.1 - 1.7e-15 56.5 7.7 2.8e-15 55.8 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EMC81660.1 - 5.1e-13 48.5 0.1 1.5e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 PA domain zf-C3HC4 PF00097.20 EMC81660.1 - 1.5e-08 34.1 8.4 2.6e-08 33.3 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC81660.1 - 7.2e-08 32.4 6.6 1.4e-07 31.5 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC81660.1 - 6.3e-07 29.3 8.6 1.1e-06 28.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC81660.1 - 9e-07 28.5 7.1 1.5e-06 27.8 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC81660.1 - 1e-06 28.2 5.7 1.7e-06 27.5 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC81660.1 - 0.0013 18.5 6.2 0.0033 17.2 4.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EMC81660.1 - 0.097 12.3 8.6 0.18 11.5 5.9 1.5 1 0 0 1 1 1 0 PHD-finger Baculo_11_kDa PF06143.6 EMC81660.1 - 0.12 11.7 1.4 1.9 7.9 0.2 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family RINGv PF12906.2 EMC81660.1 - 0.18 11.8 7.7 0.4 10.7 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EMC81660.1 - 0.49 10.0 8.6 1.1 8.9 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2976 PF11190.3 EMC81660.1 - 0.8 9.2 3.3 2 7.9 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) FANCL_C PF11793.3 EMC81660.1 - 5.5 7.0 8.8 44 4.1 6.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EMC81660.1 - 9.1 6.0 10.4 9.3 6.0 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Profilin PF00235.14 EMC81661.1 - 9.4e-12 45.1 0.0 1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Pox_MCEL PF03291.11 EMC81662.1 - 2e-107 358.8 0.5 2.3e-107 358.7 0.3 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 EMC81662.1 - 1.4e-12 47.4 0.1 2.8e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC81662.1 - 3.2e-09 36.7 0.0 5.1e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC81662.1 - 8.9e-09 35.7 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC81662.1 - 1.7e-07 31.8 0.0 2.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC81662.1 - 2.7e-06 27.6 0.1 5.1e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC81662.1 - 4.1e-06 27.1 0.0 7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMC81662.1 - 0.0027 17.3 0.1 0.0051 16.4 0.1 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EMC81662.1 - 0.0049 16.5 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMC81662.1 - 0.012 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.9 EMC81662.1 - 0.012 14.9 0.0 0.048 13.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EMC81662.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EMC81662.1 - 0.032 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_20 PF12147.3 EMC81662.1 - 0.078 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase 7tm_1 PF00001.16 EMC81663.1 - 4.1e-41 140.8 38.8 5.3e-39 133.9 26.9 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81663.1 - 7.5e-10 38.4 37.7 1.6e-09 37.3 26.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 EMC81664.1 - 6.9e-38 130.2 26.0 6.7e-36 123.7 18.0 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81664.1 - 5.7e-10 38.7 17.9 1.5e-07 30.8 12.4 2.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC81664.1 - 0.0026 16.9 25.1 11 5.0 17.4 3.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3278 PF11683.3 EMC81664.1 - 0.016 15.2 3.6 0.016 15.2 2.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) Nucleoplasmin PF03066.10 EMC81665.1 - 0.038 13.4 0.6 0.043 13.3 0.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 EMC81665.1 - 0.15 12.5 3.9 0.2 12.0 2.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EMC81665.1 - 2.5 8.4 6.3 3.7 7.9 4.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CKS PF01111.14 EMC81666.1 - 1.2e-30 105.1 1.2 1.3e-30 105.0 0.8 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SH3_4 PF06347.8 EMC81666.1 - 0.11 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial SH3 domain Ribosomal_L7Ae PF01248.21 EMC81667.1 - 2.7e-21 74.8 0.2 5.9e-21 73.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PhoU_div PF01865.11 EMC81667.1 - 0.051 12.7 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF47 Sema PF01403.14 EMC81669.1 - 1e-143 479.0 0.1 1.3e-143 478.6 0.1 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 EMC81669.1 - 2.6e-09 37.0 0.3 8.4e-09 35.4 0.2 1.9 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.11 EMC81669.1 - 7.2e-05 22.5 0.1 0.0014 18.4 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC81669.1 - 0.00019 21.4 0.0 0.00057 19.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC81669.1 - 0.0018 18.3 0.0 0.017 15.2 0.0 2.7 4 0 0 4 4 4 1 Immunoglobulin domain V-set PF07686.12 EMC81669.1 - 0.011 15.6 1.5 0.092 12.6 0.1 2.6 2 1 0 2 2 2 0 Immunoglobulin V-set domain 7tm_4 PF13853.1 EMC81670.1 - 2.1e-61 205.9 7.2 4.1e-61 204.9 5.0 1.5 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC81670.1 - 1.2e-22 80.3 6.7 1.4e-15 57.1 2.5 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 EMC81670.1 - 0.038 13.2 0.3 0.038 13.2 0.2 2.0 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc GpcrRhopsn4 PF10192.4 EMC81670.1 - 0.83 8.7 7.8 0.22 10.6 0.4 2.4 2 1 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain DUF791 PF05631.9 EMC81671.1 - 3.2e-57 193.8 4.3 1.9e-35 122.2 1.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 EMC81671.1 - 6.5e-10 38.2 10.5 8.6e-09 34.5 0.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EMC81671.1 - 0.00057 19.4 1.2 0.0007 19.1 0.2 1.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EMC81671.1 - 0.00066 18.3 1.2 0.00066 18.3 0.8 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter PDZ PF00595.19 EMC81673.1 - 9.4e-67 221.1 5.0 1.4e-14 54.0 0.1 5.4 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC81673.1 - 2e-32 110.9 0.1 6.5e-06 25.9 0.0 5.6 6 0 0 6 6 6 5 PDZ domain WW PF00397.21 EMC81673.1 - 3e-16 58.9 3.4 2.5e-09 36.7 0.3 2.7 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.16 EMC81673.1 - 9e-10 38.2 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.1 EMC81673.1 - 6.1e-09 35.5 4.3 0.062 13.1 0.0 5.1 5 0 0 5 5 5 3 Tricorn protease PDZ domain Serglycin PF04360.7 EMC81673.1 - 0.013 15.2 2.2 0.03 14.0 1.5 1.5 1 0 0 1 1 1 0 Serglycin OB_RNB PF08206.6 EMC81673.1 - 7.3 6.1 7.8 28 4.3 0.0 4.5 5 0 0 5 5 5 0 Ribonuclease B OB domain GON PF08685.6 EMC81674.1 - 1.1e-84 283.3 1.2 4.1e-84 281.4 0.9 2.1 1 0 0 1 1 1 1 GON domain TSP_1 PF00090.14 EMC81674.1 - 5.3e-60 199.3 212.1 1.4e-07 31.5 4.8 17.1 17 0 0 17 17 17 14 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 EMC81674.1 - 2.2e-32 111.2 0.1 3.8e-32 110.5 0.1 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 EMC81674.1 - 5.9e-29 101.0 0.3 1.1e-28 100.2 0.2 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 EMC81674.1 - 2.4e-15 56.9 1.8 2.4e-15 56.9 1.3 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC81674.1 - 1.2e-11 45.1 0.2 3.5e-11 43.6 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC81674.1 - 5.7e-10 39.5 1.2 1.3e-09 38.3 0.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC81674.1 - 6.7e-10 38.8 0.8 1.2e-09 37.9 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF955 PF06114.8 EMC81674.1 - 0.038 13.7 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) RPN7 PF10602.4 EMC81675.1 - 7.8e-63 211.0 2.2 1.1e-62 210.5 1.6 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EMC81675.1 - 2.7e-18 66.2 0.2 7.4e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 PCI domain DUF1732 PF08340.6 EMC81675.1 - 0.045 13.5 1.3 4.9 7.0 0.4 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF1732) SCA7 PF08313.7 EMC81676.1 - 1e-27 95.4 3.1 1e-27 95.4 2.1 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF3505 PF12013.3 EMC81676.1 - 0.22 11.7 0.1 0.22 11.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) THOC7 PF05615.8 EMC81677.1 - 9.3e-41 139.3 2.0 9.3e-41 139.3 1.4 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 UPF0193 PF05250.6 EMC81677.1 - 0.00054 19.6 5.5 0.00054 19.6 3.8 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) DUF641 PF04859.7 EMC81677.1 - 0.01 15.5 11.0 0.2 11.3 2.7 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) NRN1 PF15056.1 EMC81677.1 - 0.063 13.2 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Neuritin protein family Spc7 PF08317.6 EMC81677.1 - 0.086 11.4 17.1 0.02 13.5 3.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF607 PF04678.8 EMC81677.1 - 0.3 11.0 8.8 0.068 13.0 3.7 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF479 PF04336.7 EMC81677.1 - 0.3 11.2 3.1 0.31 11.1 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF479 DUF1319 PF07028.6 EMC81677.1 - 0.57 10.3 13.4 3.8 7.7 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) NPV_P10 PF05531.7 EMC81677.1 - 0.62 10.3 3.3 6.9 7.0 1.8 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EMC81677.1 - 1.2 8.8 9.6 6.3 6.6 2.3 2.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EMC81677.1 - 1.4 6.6 11.2 1.7 6.3 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AATF-Che1 PF13339.1 EMC81677.1 - 2.5 8.2 14.3 5.9 7.0 4.4 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor COG2 PF06148.6 EMC81677.1 - 2.8 7.8 12.6 0.3 10.9 0.9 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4168 PF13767.1 EMC81677.1 - 3.1 8.5 9.7 15 6.2 6.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) S_100 PF01023.14 EMC81678.1 - 0.0015 17.7 0.0 0.0072 15.6 0.0 2.1 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain LMP PF04778.7 EMC81678.1 - 0.025 14.3 0.3 0.054 13.2 0.2 1.6 1 0 0 1 1 1 0 LMP repeated region MARVEL PF01284.18 EMC81679.1 - 1.5e-43 148.0 6.5 1.9e-43 147.7 4.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Frizzled PF01534.12 EMC81679.1 - 0.00075 18.3 1.9 0.0032 16.3 1.4 1.8 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF588 PF04535.7 EMC81679.1 - 0.0021 17.6 1.7 0.0021 17.6 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF588) DUF1129 PF06570.6 EMC81679.1 - 0.23 10.7 1.8 0.16 11.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Collagen PF01391.13 EMC81682.1 - 0.026 14.0 2.0 0.073 12.6 1.4 1.8 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) HSNSD PF12062.3 EMC81683.1 - 2.7e-261 867.0 0.3 3.9e-261 866.5 0.2 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 EMC81683.1 - 7.8e-43 146.6 0.0 1.3e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC81683.1 - 0.0038 18.1 0.0 0.014 16.3 0.0 2.0 1 0 0 1 1 1 1 Sulfotransferase family SRCR PF00530.13 EMC81684.1 - 4.7e-119 389.3 32.4 6e-33 113.1 3.8 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Trypsin PF00089.21 EMC81684.1 - 5.2e-66 222.3 0.1 8.8e-66 221.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 EMC81684.1 - 3.1e-23 81.8 17.3 4.4e-06 26.8 1.1 4.8 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 EMC81684.1 - 2.2e-05 23.9 0.0 4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) HMG_CoA_synt_N PF01154.12 EMC81684.1 - 0.27 10.7 1.5 9.1 5.7 0.0 2.6 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal MT-A70 PF05063.9 EMC81685.1 - 4.7e-63 211.9 0.0 6.6e-63 211.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Sec23_trunk PF04811.10 EMC81686.1 - 1e-84 283.7 0.1 1.6e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC81686.1 - 3.3e-23 81.0 0.2 6.5e-23 80.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMC81686.1 - 1.1e-17 64.3 0.0 2.6e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMC81686.1 - 1.1e-14 53.7 9.7 2.3e-14 52.6 6.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMC81686.1 - 5.5e-07 29.1 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat PDZ PF00595.19 EMC81687.1 - 2.6e-05 24.2 0.0 5.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Calsarcin PF05556.6 EMC81687.1 - 3.9e-05 23.0 13.0 0.83 8.8 0.0 3.9 3 1 0 3 3 3 3 Calcineurin-binding protein (Calsarcin) PDZ_2 PF13180.1 EMC81687.1 - 0.00024 20.9 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Calsarcin PF05556.6 EMC81688.1 - 2.6e-90 302.3 0.5 3e-90 302.1 0.4 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) UCH PF00443.24 EMC81689.1 - 9.2e-20 70.8 0.9 1.5e-19 70.1 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Lipocalin PF00061.18 EMC81690.1 - 8.3e-16 58.2 1.2 9.7e-16 58.0 0.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 EMC81690.1 - 2.6e-12 46.5 1.1 3e-12 46.3 0.7 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.1 EMC81690.1 - 0.0099 16.4 2.4 0.021 15.4 1.7 1.5 1 1 0 1 1 1 1 Lipocalin-like domain DUF3994 PF13159.1 EMC81690.1 - 0.029 14.6 0.8 0.049 13.9 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3994) PDEase_I PF00233.14 EMC81691.1 - 5.6e-70 235.7 1.0 5.6e-70 235.7 0.7 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 EMC81691.1 - 3.4e-42 144.1 0.0 1.9e-21 76.8 0.0 2.8 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EMC81691.1 - 1.5e-14 54.1 0.0 6.6e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 EMC81691.1 - 5.5e-14 52.8 0.0 9.1e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 GAF domain Ribosomal_L30_N PF08079.7 EMC81692.1 - 1.2e-16 60.5 7.8 1.2e-16 60.5 5.4 1.9 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EMC81692.1 - 1.8e-13 49.8 1.4 1.8e-13 49.8 1.0 2.4 2 1 1 3 3 3 1 Ribosomal protein L30p/L7e HORMA PF02301.13 EMC81693.1 - 8.2e-44 149.5 0.2 9.4e-44 149.3 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EMC81693.1 - 0.035 13.5 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 PAC2 PF09754.4 EMC81693.1 - 0.09 12.6 0.1 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 PAC2 family zf-H2C2_2 PF13465.1 EMC81694.1 - 4e-80 260.4 117.2 1.7e-10 40.6 0.4 16.8 17 0 0 17 17 17 14 Zinc-finger double domain zf-C2H2 PF00096.21 EMC81694.1 - 3.9e-69 224.9 116.3 2.3e-06 27.6 0.4 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81694.1 - 9.9e-57 185.1 102.1 0.00039 20.5 0.2 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC81694.1 - 2.4e-36 123.0 96.2 5.6e-06 26.3 0.7 16.2 16 0 0 16 16 16 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC81694.1 - 4.6e-30 102.8 93.2 3.2e-05 23.9 1.6 15.7 16 0 0 16 16 16 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC81694.1 - 6.5e-24 83.0 87.0 0.0021 17.9 1.1 16.6 16 0 0 16 16 16 13 C2H2-type zinc finger zf-Di19 PF05605.7 EMC81694.1 - 1.1e-08 35.0 81.8 0.0067 16.5 1.5 9.9 5 2 2 9 9 9 6 Drought induced 19 protein (Di19), zinc-binding Trm112p PF03966.11 EMC81694.1 - 0.00037 20.7 11.2 0.067 13.5 0.1 5.5 3 2 1 4 4 4 1 Trm112p-like protein zf-C2H2_2 PF12756.2 EMC81694.1 - 0.0019 18.2 92.2 0.46 10.6 1.8 13.5 1 1 9 12 12 12 4 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EMC81694.1 - 0.01 15.9 4.7 0.075 13.2 0.3 15.4 16 1 0 16 16 16 0 C2H2-type zinc-finger domain zf-RING_3 PF14369.1 EMC81694.1 - 0.066 13.2 46.1 3.4 7.7 0.0 11.4 12 1 0 12 12 12 0 zinc-finger zf-CHCC PF10276.4 EMC81694.1 - 0.11 12.3 0.3 0.11 12.3 0.2 8.7 12 0 0 12 12 11 0 Zinc-finger domain zf-C2HC_2 PF13913.1 EMC81694.1 - 0.21 11.3 64.6 0.17 11.5 1.7 12.8 14 0 0 14 14 14 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 EMC81694.1 - 0.48 10.6 89.2 0.14 12.3 3.7 8.3 2 2 6 8 8 7 0 CHY zinc finger BolA PF01722.13 EMC81694.1 - 1.7 8.6 18.2 10 6.1 0.0 6.6 4 3 2 7 7 7 0 BolA-like protein DUF2369 PF10179.4 EMC81695.1 - 3.3e-104 348.1 8.6 4e-95 318.3 4.6 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.16 EMC81695.1 - 1.9e-09 37.5 1.4 0.0023 17.9 0.0 4.1 3 1 0 3 3 3 3 Fibronectin type III domain KxDL PF10241.4 EMC81696.1 - 0.0041 16.9 3.8 0.0041 16.9 2.7 3.7 2 1 1 3 3 3 2 Uncharacterized conserved protein DUF4407 PF14362.1 EMC81696.1 - 0.15 10.9 13.2 9.1 5.1 9.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_S8 PF00410.14 EMC81696.1 - 0.18 11.6 2.6 0.37 10.6 1.8 1.5 1 0 0 1 1 1 0 Ribosomal protein S8 Filament PF00038.16 EMC81696.1 - 0.46 9.9 32.3 0.57 9.6 6.1 2.8 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.1 EMC81696.1 - 6.2 5.9 37.1 2.4 7.3 5.5 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EMC81696.1 - 7.1 7.0 31.9 4.4 7.6 5.4 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 EMC81696.1 - 9.5 5.8 29.9 2.9 7.5 6.1 2.8 1 1 2 3 3 3 0 Mnd1 family 7tm_1 PF00001.16 EMC81697.1 - 1.8e-38 132.1 21.4 4.9e-24 84.8 8.2 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81697.1 - 0.00014 21.1 2.9 0.00014 21.1 2.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx ABC2_membrane_5 PF13346.1 EMC81697.1 - 0.0028 16.9 2.2 0.0028 16.9 1.5 3.4 3 0 0 3 3 3 2 ABC-2 family transporter protein 7TM_GPCR_Srw PF10324.4 EMC81697.1 - 0.0087 15.2 17.8 0.14 11.2 1.5 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF4131 PF13567.1 EMC81697.1 - 0.087 12.2 0.1 0.087 12.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Annexin PF00191.15 EMC81698.1 - 2.3e-97 318.9 9.5 4.8e-25 87.2 0.1 4.0 4 0 0 4 4 4 4 Annexin HTH_AraC PF00165.18 EMC81698.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family RNase_PH PF01138.16 EMC81699.1 - 4.9e-15 55.9 0.0 1.1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMC81699.1 - 1.3e-09 37.8 0.0 3.5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HGTP_anticodon2 PF12745.2 EMC81699.1 - 0.31 10.1 6.8 0.56 9.2 4.7 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Cyclin_N PF00134.18 EMC81700.1 - 1.1e-49 167.1 0.2 2.2e-49 166.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC81700.1 - 1.2e-28 99.4 0.9 4.8e-28 97.4 0.3 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain BBS2_C PF14782.1 EMC81701.1 - 0.00064 18.3 0.5 0.0016 17.0 0.3 1.6 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.1 EMC81701.1 - 0.002 17.8 0.0 0.0065 16.2 0.0 2.0 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region Mcm10 PF09332.6 EMC81701.1 - 0.14 11.4 0.5 0.22 10.8 0.3 1.2 1 0 0 1 1 1 0 Mcm10 replication factor GAS PF13851.1 EMC81701.1 - 0.22 10.6 9.0 0.16 11.1 1.2 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FG-GAP PF01839.18 EMC81701.1 - 0.36 10.5 1.8 8.8 6.1 0.4 2.6 2 0 0 2 2 2 0 FG-GAP repeat Ion_trans PF00520.26 EMC81702.1 - 3.5e-36 124.3 14.6 3.5e-36 124.3 10.1 1.6 2 0 0 2 2 2 1 Ion transport protein TRP_2 PF08344.6 EMC81702.1 - 1e-30 105.4 1.5 1e-30 105.4 1.0 2.2 2 0 0 2 2 2 1 Transient receptor ion channel II PKD_channel PF08016.7 EMC81702.1 - 7e-14 51.0 8.5 1.2e-13 50.3 5.9 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.2 EMC81702.1 - 1.2e-13 51.1 0.2 9.9e-10 38.6 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC81702.1 - 2.5e-11 43.7 0.0 3.8e-07 30.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EMC81702.1 - 8.5e-09 34.7 0.9 0.019 14.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC81702.1 - 1e-08 35.1 0.2 0.1 12.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81702.1 - 9e-08 31.6 1.1 0.86 10.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat A_deamin PF02137.13 EMC81703.1 - 2.7e-72 243.9 0.6 7.9e-72 242.4 0.4 1.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 EMC81703.1 - 2.2e-12 47.3 0.4 2.8e-11 43.8 0.0 2.8 4 0 0 4 4 4 1 Double-stranded RNA binding motif IL15 PF02372.10 EMC81704.1 - 1.5e-31 108.9 7.4 2.7e-30 104.9 5.1 2.0 1 1 0 1 1 1 1 Interleukin 15 IL15 PF02372.10 EMC81705.1 - 1e-13 51.2 3.0 1.4e-13 50.8 2.1 1.1 1 0 0 1 1 1 1 Interleukin 15 EF-hand_1 PF00036.27 EMC81706.1 - 3.6e-35 116.5 17.4 4.1e-09 35.0 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC81706.1 - 2e-30 104.6 9.4 2.8e-16 59.4 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC81706.1 - 1.1e-27 95.4 17.1 1.1e-12 47.3 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMC81706.1 - 1.7e-27 92.7 11.2 4e-09 35.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC81706.1 - 6.4e-21 72.7 18.7 2.9e-06 26.3 0.3 4.6 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 EMC81706.1 - 7.6e-15 54.5 0.1 2.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC81706.1 - 4.5e-06 26.3 7.8 0.23 11.1 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 EMC81706.1 - 0.00072 18.0 0.3 0.6 8.3 0.1 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) UPF0154 PF03672.8 EMC81706.1 - 0.0083 15.7 0.2 12 5.5 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 EMC81706.1 - 0.01 15.8 0.5 2.4 8.2 0.2 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EMC81706.1 - 0.011 15.4 2.7 0.31 10.7 0.1 2.6 1 1 1 3 3 3 0 Tellurite resistance protein TerB DUF3349 PF11829.3 EMC81706.1 - 0.021 15.2 1.1 4.9 7.6 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF4601 PF15373.1 EMC81706.1 - 0.022 13.6 0.1 0.044 12.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) PB1 PF00564.19 EMC81706.1 - 0.031 13.9 0.6 4.8 6.9 0.1 2.6 2 0 0 2 2 2 0 PB1 domain TBPIP PF07106.8 EMC81706.1 - 0.067 12.7 3.9 2.6 7.5 0.7 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PMBR PF09373.5 EMC81706.1 - 0.069 13.1 0.5 58 3.8 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF21 PF01595.15 EMC81706.1 - 0.07 12.4 1.4 0.73 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 Toprim_2 PF13155.1 EMC81706.1 - 0.13 12.5 1.7 8.4 6.8 0.0 2.3 1 1 1 2 2 2 0 Toprim-like SRI PF08236.6 EMC81706.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.5 3 1 0 3 3 2 0 SRI (Set2 Rpb1 interacting) domain FlgD PF03963.9 EMC81706.1 - 0.23 11.5 1.4 0.73 9.9 0.2 2.1 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF1542 PF07564.6 EMC81706.1 - 1.7 8.6 5.0 26 4.9 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) BCNT PF07572.7 EMC81706.1 - 2.3 8.2 5.1 12 5.9 0.1 2.7 3 0 0 3 3 3 0 Bucentaur or craniofacial development Cpn60_TCP1 PF00118.19 EMC81707.1 - 4.4e-23 81.6 0.0 1.3e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family FGF PF00167.13 EMC81708.1 - 3.8e-26 91.2 0.0 4.3e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.14 EMC81708.1 - 0.0013 18.1 0.2 0.0026 17.2 0.2 1.4 1 1 0 1 1 1 1 Interleukin-1 / 18 NUDIX PF00293.23 EMC81709.1 - 2.1e-20 72.7 0.0 2.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 EMC81710.1 - 1.7e-71 238.6 0.0 2.9e-43 147.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMC81710.1 - 5.2e-15 55.1 0.0 3.5e-08 32.7 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMC81710.1 - 9e-12 44.9 0.0 5.4e-05 22.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC81710.1 - 5.4e-11 42.8 0.0 2.1e-05 24.6 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 EMC81710.1 - 4.4e-10 38.8 0.4 7.3e-05 21.6 0.0 2.7 3 0 0 3 3 3 2 TIP49 C-terminus AAA_22 PF13401.1 EMC81710.1 - 3e-09 37.1 0.6 0.0015 18.7 0.0 4.3 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EMC81710.1 - 5.5e-08 32.4 0.0 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 EMC81710.1 - 7.4e-08 32.4 0.0 0.00062 19.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EMC81710.1 - 9.8e-08 31.9 0.0 0.0035 17.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMC81710.1 - 1e-07 31.5 0.4 0.024 14.0 0.1 3.4 2 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMC81710.1 - 1.1e-07 32.7 0.0 0.00066 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EMC81710.1 - 2.2e-07 30.2 0.8 0.0046 16.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EMC81710.1 - 3.6e-07 29.4 0.0 0.0073 15.4 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin Sigma54_activ_2 PF14532.1 EMC81710.1 - 9.1e-07 29.0 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EMC81710.1 - 9.6e-07 28.4 0.6 0.002 17.8 0.5 2.8 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EMC81710.1 - 1.2e-06 28.6 0.0 0.006 16.7 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EMC81710.1 - 5.6e-06 26.3 0.0 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EMC81710.1 - 7.7e-06 24.9 0.1 0.0061 15.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EMC81710.1 - 8.9e-06 25.6 0.0 0.0058 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EMC81710.1 - 5.1e-05 22.8 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMC81710.1 - 0.00015 21.5 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.1 EMC81710.1 - 0.00024 21.3 0.0 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMC81710.1 - 0.00032 20.4 0.4 0.099 12.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 EMC81710.1 - 0.00034 20.1 0.0 0.28 10.6 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Rad17 PF03215.10 EMC81710.1 - 0.00062 18.5 0.0 0.072 11.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EMC81710.1 - 0.00071 19.8 0.1 0.78 10.0 0.0 2.9 2 1 1 3 3 3 1 ABC transporter AAA_24 PF13479.1 EMC81710.1 - 0.00075 19.1 0.7 0.12 11.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EMC81710.1 - 0.0015 18.1 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 EMC81710.1 - 0.0021 17.0 0.0 0.31 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KaiC PF06745.8 EMC81710.1 - 0.0026 16.9 0.1 0.56 9.2 0.0 2.4 2 0 0 2 2 2 1 KaiC CDC48_2 PF02933.12 EMC81710.1 - 0.0049 16.4 0.1 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATP-synt_ab PF00006.20 EMC81710.1 - 0.0099 15.3 0.0 4.5 6.7 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EMC81710.1 - 0.014 15.0 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EMC81710.1 - 0.019 14.8 0.0 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.11 EMC81710.1 - 0.021 14.0 0.1 0.52 9.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EMC81710.1 - 0.029 13.9 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMC81710.1 - 0.032 14.5 0.0 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 EMC81710.1 - 0.034 13.3 0.1 0.88 8.6 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.17 EMC81710.1 - 0.035 12.9 0.1 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EMC81710.1 - 0.059 13.0 0.0 1.5 8.4 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase Cytidylate_kin2 PF13189.1 EMC81710.1 - 0.06 13.2 0.0 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family T2SE PF00437.15 EMC81710.1 - 0.13 11.0 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Guanylate_kin PF00625.16 EMC81710.1 - 0.21 11.0 0.2 14 5.0 0.0 3.2 2 2 2 4 4 4 0 Guanylate kinase AFG1_ATPase PF03969.11 EMC81710.1 - 0.21 10.3 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.4 EMC81710.1 - 0.26 10.2 0.0 0.69 8.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sprouty PF05210.8 EMC81712.1 - 1.1e-33 115.5 32.8 1.6e-33 114.9 22.7 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) XPA_C PF05181.7 EMC81713.1 - 3.6e-29 100.0 1.0 4e-29 99.9 0.7 1.0 1 0 0 1 1 1 1 XPA protein C-terminus MIF4G_like_2 PF09090.6 EMC81714.1 - 4.5e-74 248.8 3.2 8.3e-74 248.0 1.5 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 EMC81714.1 - 2.3e-57 193.5 3.3 3.3e-54 183.2 1.5 3.7 3 1 0 3 3 3 1 MIF4G like MIF4G PF02854.14 EMC81714.1 - 9.2e-25 87.2 0.0 9.2e-25 87.2 0.0 2.9 4 0 0 4 4 4 1 MIF4G domain Mnd1 PF03962.10 EMC81714.1 - 0.0086 15.7 0.8 0.02 14.5 0.5 1.6 1 0 0 1 1 1 1 Mnd1 family DUF4611 PF15387.1 EMC81714.1 - 0.022 14.8 0.7 0.022 14.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Voldacs PF03517.8 EMC81714.1 - 0.023 14.5 0.3 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Vfa1 PF08432.5 EMC81714.1 - 0.31 11.0 5.1 0.6 10.1 3.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 EMC81714.1 - 1.3 9.3 12.9 0.036 14.3 4.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FlxA PF14282.1 EMC81714.1 - 3.9 7.4 6.8 1.7 8.5 2.7 1.9 2 0 0 2 2 2 0 FlxA-like protein Rhodanese PF00581.15 EMC81715.1 - 6.7e-10 39.3 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Tropomodulin PF03250.9 EMC81716.1 - 2.1e-67 225.1 5.0 4.7e-67 224.0 3.5 1.6 1 0 0 1 1 1 1 Tropomodulin DAGK_acc PF00609.14 EMC81717.1 - 7.5e-50 169.2 0.0 2.6e-49 167.4 0.0 1.9 2 1 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EMC81717.1 - 1.4e-26 92.4 0.0 3.2e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.18 EMC81717.1 - 7.1e-19 68.0 1.3 3e-11 43.6 0.1 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.17 EMC81717.1 - 1.2e-16 60.1 39.5 6.1e-12 45.0 4.4 3.6 3 1 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EMC81717.1 - 0.0047 16.9 4.9 0.0047 16.9 3.4 4.1 4 1 0 4 4 4 2 C1-like domain zf-met PF12874.2 EMC81717.1 - 3.8 7.8 11.5 2.7 8.3 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Gag_p30 PF02093.11 EMC81718.1 - 3.6e-21 75.3 0.0 4e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Aconitase PF00330.15 EMC81719.1 - 1.5e-137 458.8 0.0 1.9e-137 458.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMC81719.1 - 1.5e-44 151.2 0.0 3.2e-43 146.9 0.0 2.3 2 0 0 2 2 2 1 Aconitase C-terminal domain PNP_UDP_1 PF01048.15 EMC81720.1 - 1e-48 165.3 0.0 1.1e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NLPC_P60 PF00877.14 EMC81720.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 NlpC/P60 family TFIIE_beta PF02186.10 EMC81720.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 TFIIE beta subunit core domain 4F5 PF04419.9 EMC81723.1 - 1.9e-07 31.6 6.7 1.9e-07 31.6 4.7 2.1 2 0 0 2 2 2 1 4F5 protein family YtxC PF08812.6 EMC81723.1 - 0.38 10.2 2.2 0.42 10.0 1.5 1.0 1 0 0 1 1 1 0 YtxC-like family Toxin_39 PF15500.1 EMC81723.1 - 0.7 10.0 4.6 1.3 9.2 3.2 1.4 1 1 0 1 1 1 0 Putative RNase-like toxin OmpH PF03938.9 EMC81723.1 - 8.6 6.2 13.8 9.3 6.1 9.6 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BIR PF00653.16 EMC81724.1 - 2.5e-56 187.9 14.2 7.2e-23 80.8 0.3 3.7 3 0 0 3 3 3 3 Inhibitor of Apoptosis domain NACHT PF05729.7 EMC81724.1 - 6.8e-25 87.6 0.0 1.9e-24 86.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain LRR_4 PF12799.2 EMC81724.1 - 0.00084 18.9 7.4 4.4 7.0 0.0 5.8 4 3 3 7 7 7 1 Leucine Rich repeats (2 copies) Latarcin PF10279.4 EMC81724.1 - 0.0011 19.0 2.1 4.9 7.4 0.0 4.4 4 1 0 4 4 4 2 Latarcin precursor AAA_22 PF13401.1 EMC81724.1 - 0.003 17.7 0.5 0.098 12.8 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.1 EMC81724.1 - 0.04 13.6 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EMC81724.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMC81724.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-C3HC PF07967.8 EMC81724.1 - 1.6 8.5 12.6 29 4.4 0.1 4.6 4 0 0 4 4 4 0 C3HC zinc finger-like Ssl1 PF04056.9 EMC81725.1 - 6.4e-93 309.7 0.1 8.7e-93 309.2 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EMC81725.1 - 2.8e-16 60.0 0.0 4.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 EMC81725.1 - 1.6e-14 53.6 27.1 2.1e-14 53.2 13.5 2.5 2 0 0 2 2 2 1 TFIIH C1-like domain VWA PF00092.23 EMC81725.1 - 9.9e-06 25.3 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC81725.1 - 0.0044 16.7 0.0 0.0099 15.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.16 EMC81725.1 - 1.2 9.1 17.6 0.2 11.5 5.9 3.0 3 0 0 3 3 3 0 IBR domain DZR PF12773.2 EMC81725.1 - 1.9 8.3 23.0 1.6 8.6 0.7 3.4 2 1 1 3 3 3 0 Double zinc ribbon Occludin_ELL PF07303.8 EMC81727.1 - 9.8e-31 106.5 10.1 2.1e-30 105.4 7.0 1.6 1 0 0 1 1 1 1 Occludin homology domain MARVEL PF01284.18 EMC81727.1 - 6.5e-17 61.7 8.4 8.4e-17 61.3 5.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Shisa PF13908.1 EMC81727.1 - 0.057 13.5 0.1 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tex_N PF09371.5 EMC81727.1 - 0.067 12.5 2.0 0.12 11.7 1.4 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF429 PF04250.8 EMC81727.1 - 0.2 10.8 0.7 0.32 10.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Med9 PF07544.8 EMC81727.1 - 0.31 10.8 1.9 1.4 8.7 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF202 PF02656.10 EMC81727.1 - 0.52 10.5 2.8 6 7.1 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Yae1_N PF09811.4 EMC81728.1 - 2.8e-08 33.1 38.4 3.4 7.2 20.6 4.6 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Cadherin PF00028.12 EMC81729.1 - 2.8e-33 114.0 1.1 4.3e-13 49.3 0.0 3.4 3 0 0 3 3 3 3 Cadherin domain Cadherin_C PF01049.12 EMC81729.1 - 1.2e-18 67.6 0.2 2.4e-17 63.3 0.2 2.5 1 1 0 1 1 1 1 Cadherin cytoplasmic region Herpes_gE PF02480.11 EMC81729.1 - 0.0059 14.9 0.9 1.5 7.0 0.1 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.6 EMC81729.1 - 0.12 12.1 0.5 0.31 10.7 0.3 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MRAP PF15183.1 EMC81729.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family zf-C2H2_6 PF13912.1 EMC81730.1 - 1.6e-30 103.9 48.0 7.1e-08 32.0 0.9 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC81730.1 - 4.1e-10 39.5 43.2 0.049 13.8 0.3 8.2 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC81730.1 - 9.4e-08 32.0 53.4 0.0045 17.1 0.4 8.8 8 1 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EMC81730.1 - 1.3e-05 25.2 64.8 0.082 13.2 0.3 8.8 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81730.1 - 0.028 14.7 53.1 0.043 14.1 0.2 8.9 9 0 0 9 9 9 0 C2H2-type zinc finger TLD PF07534.11 EMC81731.1 - 2.8e-40 137.5 0.2 5.7e-40 136.5 0.1 1.5 1 0 0 1 1 1 1 TLD LysM PF01476.15 EMC81731.1 - 6.1e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain GRAM PF02893.15 EMC81731.1 - 0.0058 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain MOSC PF03473.12 EMC81731.1 - 0.091 12.2 1.3 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 MOSC domain Costars PF14705.1 EMC81732.1 - 3.2e-34 116.7 0.0 4.1e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Costars SARS_lipid_bind PF09399.5 EMC81733.1 - 0.007 16.3 3.3 44 4.1 0.0 5.2 4 2 3 7 7 7 2 SARS lipid binding protein BAF PF02961.9 EMC81734.1 - 1.4e-16 60.5 0.1 1.5e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor 7tm_1 PF00001.16 EMC81735.1 - 1.6e-11 43.8 5.1 1.8e-11 43.7 3.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) C2-set_2 PF08205.7 EMC81736.1 - 9.1e-28 96.0 4.2 4.1e-19 68.2 0.0 4.5 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 EMC81736.1 - 5e-26 90.6 8.0 1.3e-06 28.4 0.1 5.6 5 1 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 EMC81736.1 - 1.1e-17 64.2 12.8 3e-05 24.4 0.0 6.3 5 3 0 5 5 5 4 Immunoglobulin domain I-set PF07679.11 EMC81736.1 - 4.2e-16 58.5 13.2 0.0011 18.7 0.1 7.7 5 2 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.12 EMC81736.1 - 2.5e-13 49.9 11.0 7.9e-05 22.5 0.0 7.4 5 4 1 6 6 6 3 Immunoglobulin V-set domain ig PF00047.20 EMC81736.1 - 3e-12 46.4 12.7 0.0017 18.3 0.1 7.3 6 3 0 6 6 6 4 Immunoglobulin domain C1-set PF07654.10 EMC81736.1 - 1.4e-09 37.7 8.5 3.5e-05 23.7 0.0 4.4 5 1 0 5 5 5 2 Immunoglobulin C1-set domain DUF4366 PF14283.1 EMC81736.1 - 0.0019 17.6 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF1661 PF07877.6 EMC81737.1 - 0.011 15.1 0.2 0.011 15.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) DUF3832 PF12909.2 EMC81737.1 - 0.054 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) DUF2028 PF09667.5 EMC81738.1 - 4.4e-38 130.7 9.0 4.4e-38 130.7 6.3 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF2028) HMG_box PF00505.14 EMC81738.1 - 2.7e-17 62.7 0.9 7.9e-17 61.2 0.6 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC81738.1 - 4.3e-10 39.7 1.0 4.3e-10 39.7 0.7 2.4 3 0 0 3 3 3 1 HMG-box domain Caldesmon PF02029.10 EMC81739.1 - 3.4e-188 626.0 207.6 9.4e-142 472.8 57.8 3.3 1 1 1 2 2 2 2 Caldesmon Ras PF00071.17 EMC81740.1 - 1.6e-30 105.6 0.0 2.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81740.1 - 1e-10 42.1 0.0 1.6e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81740.1 - 0.0003 20.0 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Y_phosphatase PF00102.22 EMC81741.1 - 4.7e-84 281.3 2.8 4.7e-84 281.3 2.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase fn3 PF00041.16 EMC81741.1 - 2.8e-27 94.6 20.5 4.3e-09 36.3 0.5 6.2 6 0 0 6 6 6 5 Fibronectin type III domain DSPc PF00782.15 EMC81741.1 - 5.5e-05 22.7 0.1 0.00019 21.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC81741.1 - 0.00011 22.2 0.3 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC81741.1 - 0.00037 20.7 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTB PF08416.8 EMC81742.1 - 8.2e-52 174.5 1.4 1.6e-51 173.6 1.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.23 EMC81742.1 - 8.1e-11 41.1 0.0 1.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC81742.1 - 3.1e-06 26.6 0.0 6.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.18 EMC81742.1 - 1.5e-05 24.9 0.7 4.4e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.12 EMC81742.1 - 5.3e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC81742.1 - 0.001 19.2 0.0 0.003 17.7 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SAM_PNT PF02198.11 EMC81742.1 - 0.085 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PSP1 PF04468.7 EMC81743.1 - 0.018 15.0 0.3 0.053 13.5 0.1 1.9 2 0 0 2 2 2 0 PSP1 C-terminal conserved region WD40 PF00400.27 EMC81744.1 - 4.3e-41 137.3 0.7 3.9e-11 42.3 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EMC81744.1 - 0.00089 18.7 0.0 0.0046 16.4 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain Me-amine-dh_H PF06433.6 EMC81744.1 - 0.052 12.1 0.1 1.8 7.1 0.0 2.6 3 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DUF3312 PF11768.3 EMC81744.1 - 0.095 10.9 0.0 10 4.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) DeoC PF01791.4 EMC81745.1 - 4.4e-37 127.6 0.0 5.1e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase PTR2 PF00854.16 EMC81746.1 - 7.9e-26 90.7 16.1 1e-17 64.0 2.0 2.7 2 1 1 3 3 3 2 POT family TPR_1 PF00515.23 EMC81746.1 - 0.046 13.3 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MAPEG PF01124.13 EMC81747.1 - 1.9e-21 76.0 0.1 2.2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 MAPEG family LIM PF00412.17 EMC81748.1 - 1.1e-30 105.4 22.3 2.4e-15 56.3 5.8 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 EMC81748.1 - 3.8 7.5 22.7 0.35 10.9 4.9 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain PrmA PF06325.8 EMC81749.1 - 1.2e-09 37.7 0.0 5.5e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_11 PF13414.1 EMC81749.1 - 1.4e-07 31.0 0.1 3.1e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 TPR repeat Methyltransf_18 PF12847.2 EMC81749.1 - 2.4e-07 31.3 0.0 6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPR_2 PF07719.12 EMC81749.1 - 5.6e-07 28.9 3.7 0.0022 17.7 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC81749.1 - 4.3e-05 22.9 0.9 0.22 11.2 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat Methyltransf_26 PF13659.1 EMC81749.1 - 0.00012 22.0 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMC81749.1 - 0.00022 20.7 0.0 0.00053 19.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EMC81749.1 - 0.00028 20.3 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TPR_14 PF13428.1 EMC81749.1 - 0.00047 20.5 1.0 0.045 14.4 0.0 3.3 3 1 1 4 4 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC81749.1 - 0.003 18.1 0.9 0.039 14.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_31 PF13847.1 EMC81749.1 - 0.0073 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC81749.1 - 0.0076 16.7 0.0 0.035 14.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 EMC81749.1 - 0.0098 15.0 0.1 0.027 13.5 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EMC81749.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMC81749.1 - 0.032 14.6 0.0 0.084 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TPR_17 PF13431.1 EMC81749.1 - 0.044 13.9 0.7 1.5 9.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RrnaAD PF00398.15 EMC81749.1 - 0.078 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 EMC81749.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Pox_J1 PF03338.10 EMC81749.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus J1 protein TPR_12 PF13424.1 EMC81749.1 - 0.24 11.3 2.0 1.6 8.7 0.0 2.8 2 1 2 4 4 3 0 Tetratricopeptide repeat Solute_trans_a PF03619.11 EMC81750.1 - 5.2e-100 334.2 18.0 6.2e-100 334.0 12.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha 7tm_1 PF00001.16 EMC81751.1 - 1.1e-38 132.8 10.4 1.1e-38 132.8 7.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81751.1 - 0.004 16.3 15.8 0.061 12.4 9.2 3.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TPR_12 PF13424.1 EMC81752.1 - 1.1e-17 63.7 11.2 2.9e-08 33.5 0.5 4.4 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMC81752.1 - 7.8e-11 41.4 16.4 4.3e-05 23.0 0.7 4.6 3 1 3 6 6 6 4 TPR repeat TPR_1 PF00515.23 EMC81752.1 - 7.3e-08 31.7 10.1 0.0043 16.5 0.3 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC81752.1 - 4.4e-07 29.9 10.0 7.5e-06 26.0 0.1 4.0 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMC81752.1 - 1.4e-06 27.6 11.6 0.43 10.4 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC81752.1 - 2.6e-06 26.8 17.0 0.47 10.5 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC81752.1 - 3e-06 27.4 3.8 0.27 11.6 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC81752.1 - 3.4e-06 27.1 8.2 0.17 12.5 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC81752.1 - 1.4e-05 24.8 6.1 1.7 9.0 0.1 5.8 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC81752.1 - 3.5e-05 23.2 2.7 7.9 6.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC81752.1 - 8.5e-05 22.3 2.6 0.048 13.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC81752.1 - 0.0024 18.4 6.8 0.63 10.7 0.0 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMC81752.1 - 0.0074 15.5 0.1 3.4 6.9 0.0 2.7 2 0 0 2 2 2 1 SHNi-TPR TPR_20 PF14561.1 EMC81752.1 - 0.017 15.1 6.3 6.1 7.0 0.2 4.5 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMC81752.1 - 0.1 13.0 3.5 23 5.8 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC81752.1 - 0.31 11.6 9.4 86 3.9 0.1 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 EMC81752.1 - 0.34 10.2 8.2 0.95 8.8 0.1 2.8 2 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF4137 PF13593.1 EMC81753.1 - 2.2e-74 250.3 22.0 2.5e-74 250.2 15.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EMC81753.1 - 3.3e-15 55.9 13.4 3.3e-15 55.9 9.3 2.4 2 1 0 2 2 2 1 Sodium Bile acid symporter family MRAP PF15183.1 EMC81753.1 - 5.4 6.7 6.2 0.35 10.4 0.2 2.0 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Reeler PF02014.11 EMC81754.1 - 2.9e-33 114.9 0.0 3.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Reeler domain LSM PF01423.17 EMC81755.1 - 5.4e-18 64.2 0.1 6.2e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMC81755.1 - 2.5e-05 24.1 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain ArgK PF03308.11 EMC81756.1 - 9.4e-94 313.1 0.2 1.3e-93 312.6 0.2 1.2 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 EMC81756.1 - 1.8e-06 27.5 0.0 7.7e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EMC81756.1 - 1.9e-05 24.8 1.6 0.0022 18.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 EMC81756.1 - 0.0002 21.0 0.0 0.00044 19.8 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EMC81756.1 - 0.0003 20.6 1.6 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 EMC81756.1 - 0.00088 19.2 0.1 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EMC81756.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 EMC81756.1 - 0.002 18.4 0.2 0.0068 16.7 0.0 1.9 2 1 0 2 2 1 1 ABC transporter AAA_10 PF12846.2 EMC81756.1 - 0.0022 17.4 0.3 0.0031 17.0 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EMC81756.1 - 0.0033 17.1 0.4 0.015 15.0 0.0 2.2 3 0 0 3 3 2 1 Part of AAA domain MobB PF03205.9 EMC81756.1 - 0.0034 17.0 0.1 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EMC81756.1 - 0.0064 16.4 1.6 0.023 14.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 EMC81756.1 - 0.0067 15.8 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 EMC81756.1 - 0.011 15.9 0.1 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMC81756.1 - 0.013 16.3 0.1 0.034 14.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMC81756.1 - 0.014 15.7 0.1 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMC81756.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EMC81756.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Mg_chelatase PF01078.16 EMC81756.1 - 0.021 13.9 0.1 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 EMC81756.1 - 0.021 14.7 0.0 0.064 13.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 EMC81756.1 - 0.022 14.1 0.0 0.094 12.1 0.0 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EMC81756.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 EMC81756.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HD_assoc PF13286.1 EMC81756.1 - 0.039 14.2 0.6 0.31 11.3 0.1 2.5 2 1 1 3 3 2 0 Phosphohydrolase-associated domain KTI12 PF08433.5 EMC81756.1 - 0.057 12.6 0.1 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EMC81756.1 - 0.058 13.5 0.1 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EMC81756.1 - 0.085 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) OTU PF02338.14 EMC81757.1 - 1.6e-06 28.6 0.0 4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease SMN PF06003.7 EMC81757.1 - 0.013 14.6 0.0 0.013 14.6 0.0 3.4 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) ABC_tran PF00005.22 EMC81758.1 - 6.2e-38 130.2 0.0 1.2e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EMC81758.1 - 8.5e-15 54.0 7.3 2.6e-14 52.4 5.1 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EMC81758.1 - 4.7e-12 46.4 3.5 0.041 13.8 0.1 4.9 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EMC81758.1 - 1.4e-10 40.7 3.3 0.0019 17.5 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EMC81758.1 - 1e-08 34.6 0.2 0.21 10.6 0.0 4.2 4 0 0 4 4 4 3 AAA ATPase domain AAA_16 PF13191.1 EMC81758.1 - 2.6e-08 34.0 0.0 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.22 EMC81758.1 - 1e-07 31.2 1.6 1e-07 31.2 1.1 3.7 5 0 0 5 5 4 1 4Fe-4S binding domain AAA_22 PF13401.1 EMC81758.1 - 2.7e-06 27.5 0.1 0.0022 18.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMC81758.1 - 1.3e-05 24.6 0.1 0.061 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EMC81758.1 - 2.2e-05 24.6 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EMC81758.1 - 4.1e-05 22.8 2.6 0.083 12.0 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4_6 PF12837.2 EMC81758.1 - 4.8e-05 23.0 0.8 4.8e-05 23.0 0.6 3.5 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_17 PF13207.1 EMC81758.1 - 7.4e-05 23.5 0.3 0.59 10.9 0.1 3.0 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 EMC81758.1 - 0.00013 22.4 0.6 0.62 10.5 0.0 3.5 3 1 0 3 3 3 1 Miro-like protein NACHT PF05729.7 EMC81758.1 - 0.00013 21.6 0.5 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EMC81758.1 - 0.00052 19.9 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC81758.1 - 0.00054 20.2 0.0 0.45 10.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMC81758.1 - 0.0012 18.2 0.0 0.54 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMC81758.1 - 0.0018 17.9 0.4 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_7 PF12838.2 EMC81758.1 - 0.002 18.4 1.2 0.002 18.4 0.8 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 EMC81758.1 - 0.002 18.2 0.0 1.8 8.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_23 PF13476.1 EMC81758.1 - 0.002 18.4 0.1 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 EMC81758.1 - 0.0026 17.5 2.0 0.0026 17.5 1.4 3.2 3 0 0 3 3 2 1 4Fe-4S binding domain SRP54 PF00448.17 EMC81758.1 - 0.0029 17.0 1.9 0.28 10.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain VirE PF05272.6 EMC81758.1 - 0.0043 16.5 0.0 0.96 8.8 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E UPF0079 PF02367.12 EMC81758.1 - 0.0062 16.1 0.2 0.089 12.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_16 PF13484.1 EMC81758.1 - 0.0082 16.8 0.5 0.0082 16.8 0.3 3.0 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EMC81758.1 - 0.0086 16.3 1.7 0.0086 16.3 1.2 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 EMC81758.1 - 0.013 16.0 4.2 0.013 16.0 2.9 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_10 PF13237.1 EMC81758.1 - 0.014 15.1 2.0 0.014 15.1 1.4 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EMC81758.1 - 0.017 14.6 0.5 0.33 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMC81758.1 - 0.018 14.9 0.1 3.4 7.6 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EMC81758.1 - 0.021 14.7 0.4 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EMC81758.1 - 0.05 12.2 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EMC81758.1 - 0.058 12.2 0.1 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 EMC81758.1 - 0.062 12.0 0.2 6.3 5.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 EMC81758.1 - 0.068 12.8 1.1 0.95 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EMC81758.1 - 0.093 12.2 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMC81758.1 - 0.13 12.2 0.0 18 5.2 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.1 EMC81758.1 - 0.2 11.7 10.4 0.1 12.6 0.9 2.3 2 1 1 3 3 2 0 4Fe-4S dicluster domain FtsK_SpoIIIE PF01580.13 EMC81758.1 - 0.2 11.0 0.3 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Fer4_21 PF14697.1 EMC81758.1 - 0.22 11.3 18.7 0.02 14.7 8.8 2.3 2 1 1 3 3 2 0 4Fe-4S dicluster domain AAA_10 PF12846.2 EMC81758.1 - 1.7 8.0 4.9 11 5.3 0.1 2.8 3 1 0 3 3 3 0 AAA-like domain APC10 PF03256.11 EMC81759.1 - 3.1e-79 265.0 0.1 3.6e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) CHB_HEX_C_1 PF13290.1 EMC81759.1 - 0.0057 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain PITH PF06201.8 EMC81759.1 - 0.018 14.7 0.1 0.075 12.8 0.1 1.8 1 1 0 1 1 1 0 PITH domain PH PF00169.24 EMC81760.1 - 6.3e-16 58.4 1.8 1e-15 57.7 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EMC81760.1 - 3e-07 30.6 0.4 1.4e-06 28.5 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMC81760.1 - 0.051 13.4 0.3 0.14 12.0 0.2 1.7 1 1 0 1 1 1 0 PH domain IL15 PF02372.10 EMC81763.1 - 7.2e-46 155.3 11.4 1e-45 154.8 7.9 1.2 1 0 0 1 1 1 1 Interleukin 15 RhoGEF PF00621.15 EMC81763.1 - 0.0034 17.2 2.0 0.0035 17.2 1.4 1.2 1 0 0 1 1 1 1 RhoGEF domain CTD_bind PF04818.8 EMC81763.1 - 0.59 10.4 2.5 31 4.9 0.1 3.1 2 1 1 3 3 3 0 RNA polymerase II-binding domain. NOA36 PF06524.7 EMC81764.1 - 1.8e-153 510.3 38.8 2.1e-153 510.1 26.9 1.0 1 0 0 1 1 1 1 NOA36 protein zf-RING_2 PF13639.1 EMC81765.1 - 1e-13 50.8 6.4 2.1e-13 49.8 4.4 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EMC81765.1 - 3.3e-09 36.3 0.0 6.3e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EMC81765.1 - 3.9e-08 33.2 2.1 8.6e-08 32.1 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC81765.1 - 7.5e-08 31.9 3.6 1.4e-07 31.0 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC81765.1 - 1.6e-07 30.8 4.7 3.3e-07 29.8 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC81765.1 - 3.1e-07 30.0 4.0 6.2e-07 29.0 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC81765.1 - 1.4e-06 28.2 6.8 1.4e-06 28.2 4.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) UPF0233 PF06781.7 EMC81765.1 - 0.0052 16.3 0.5 0.012 15.2 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) zf-Apc11 PF12861.2 EMC81765.1 - 0.0093 15.7 2.3 0.018 14.8 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ninjurin PF04923.7 EMC81765.1 - 0.02 14.6 0.6 0.047 13.4 0.4 1.6 1 0 0 1 1 1 0 Ninjurin PspB PF06667.7 EMC81765.1 - 0.036 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B PgaD PF13994.1 EMC81765.1 - 0.065 12.7 0.4 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 PgaD-like protein BatD PF13584.1 EMC81765.1 - 0.086 11.4 0.2 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance PHD PF00628.24 EMC81765.1 - 0.45 10.2 8.1 0.68 9.6 2.9 2.5 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.2 EMC81765.1 - 1.1 9.4 7.4 0.37 10.8 2.9 1.9 2 0 0 2 2 2 0 RING-variant domain RabGAP-TBC PF00566.13 EMC81766.1 - 1.8e-47 161.5 0.1 1.2e-46 158.8 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 EMC81766.1 - 3e-37 125.9 0.2 3.3e-18 64.9 0.0 2.5 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.27 EMC81766.1 - 0.00066 18.8 0.1 0.044 13.0 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EMC81766.1 - 0.0076 16.0 0.1 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EMC81766.1 - 0.055 13.6 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair ELMO_CED12 PF04727.8 EMC81767.1 - 3.2e-50 169.9 0.1 5.4e-50 169.2 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Glyco_transf_54 PF04666.8 EMC81768.1 - 5e-119 396.4 0.7 6.1e-119 396.2 0.5 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Calreticulin PF00262.13 EMC81769.1 - 4.2e-157 522.5 16.1 4.9e-157 522.2 11.1 1.0 1 0 0 1 1 1 1 Calreticulin family NAF PF03822.9 EMC81769.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 NAF domain DUF2205 PF10224.4 EMC81770.1 - 8.8e-34 114.9 6.9 1.1e-33 114.5 4.8 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Nse5 PF08691.5 EMC81770.1 - 0.0022 16.5 0.3 0.0022 16.5 0.2 1.1 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 IncA PF04156.9 EMC81770.1 - 0.0036 16.9 4.8 0.0037 16.8 3.3 1.1 1 0 0 1 1 1 1 IncA protein DUF972 PF06156.8 EMC81770.1 - 0.0036 17.6 4.4 0.0046 17.2 2.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EMC81770.1 - 0.0079 16.1 1.0 0.0079 16.1 0.7 2.0 1 1 1 2 2 2 1 bZIP transcription factor DUF2683 PF10884.3 EMC81770.1 - 0.0091 15.9 0.6 0.012 15.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2683) HALZ PF02183.13 EMC81770.1 - 0.011 15.4 6.7 0.054 13.2 0.5 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF3355 PF11835.3 EMC81770.1 - 0.036 13.8 1.0 0.043 13.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) RINT1_TIP1 PF04437.8 EMC81770.1 - 0.049 12.1 2.3 0.051 12.1 1.6 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Seadorna_VP6 PF07407.6 EMC81770.1 - 0.091 11.5 0.5 0.095 11.4 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Syntaxin-6_N PF09177.6 EMC81770.1 - 0.11 12.9 2.0 0.13 12.6 1.4 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal APG6 PF04111.7 EMC81770.1 - 0.14 11.1 6.6 0.16 10.9 4.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EMC81770.1 - 0.16 11.4 6.6 0.072 12.5 1.0 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF3450 PF11932.3 EMC81770.1 - 0.16 11.1 4.5 0.19 10.9 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spectrin PF00435.16 EMC81770.1 - 0.21 11.9 3.9 0.27 11.5 2.7 1.2 1 0 0 1 1 1 0 Spectrin repeat Sas10_Utp3 PF04000.10 EMC81770.1 - 0.31 11.2 2.5 0.23 11.6 0.8 1.6 1 1 1 2 2 2 0 Sas10/Utp3/C1D family DUF904 PF06005.7 EMC81770.1 - 0.48 10.7 8.2 0.77 10.0 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 EMC81770.1 - 0.49 9.9 5.9 0.56 9.8 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EMC81770.1 - 1 7.1 5.5 0.96 7.2 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 EMC81770.1 - 1.4 9.1 7.4 0.23 11.6 1.1 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.10 EMC81770.1 - 3.6 7.4 8.2 0.98 9.2 0.4 2.7 1 1 1 2 2 2 0 Basic region leucine zipper MAPEG PF01124.13 EMC81772.1 - 1.8e-05 24.3 2.4 2.1e-05 24.1 1.7 1.1 1 0 0 1 1 1 1 MAPEG family MORN PF02493.15 EMC81773.1 - 3.2e-14 51.6 21.9 0.00079 19.0 0.6 6.8 7 0 0 7 7 7 4 MORN repeat MORN_2 PF07661.8 EMC81773.1 - 0.00014 21.4 6.6 0.064 13.2 0.0 5.1 5 1 0 6 6 6 2 MORN repeat variant CD20 PF04103.10 EMC81774.1 - 1.1e-15 57.8 9.8 1.4e-15 57.5 6.8 1.1 1 0 0 1 1 1 1 CD20-like family Caps_synth_CapC PF14102.1 EMC81774.1 - 0.011 15.8 4.8 0.011 15.8 3.3 1.6 1 1 0 1 1 1 0 Capsule biosynthesis CapC 7TMR-DISM_7TM PF07695.6 EMC81774.1 - 0.11 12.2 5.0 0.17 11.5 3.5 1.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling PMP22_Claudin PF00822.15 EMC81774.1 - 0.16 11.6 6.9 0.077 12.6 2.9 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF2919 PF11143.3 EMC81774.1 - 0.19 11.5 1.8 0.28 11.0 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2919) DUF3671 PF12420.3 EMC81774.1 - 0.3 11.0 1.8 0.53 10.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF1772 PF08592.6 EMC81774.1 - 0.5 10.1 5.6 0.23 11.1 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) SUR7 PF06687.7 EMC81774.1 - 1.6 8.2 8.2 2 7.9 2.0 2.2 1 1 1 2 2 2 0 SUR7/PalI family NfeD PF01957.13 EMC81774.1 - 5.4 7.1 8.6 0.52 10.4 1.6 2.2 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Ras PF00071.17 EMC81775.1 - 1.8e-30 105.4 0.0 2e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81775.1 - 1.5e-11 44.8 0.0 3.6e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC81775.1 - 6.1e-09 35.3 0.0 6.6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC81775.1 - 8.5e-05 21.8 0.0 9.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC81775.1 - 0.00016 20.5 0.3 0.00094 17.9 0.2 2.0 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 EMC81775.1 - 0.00049 19.5 0.0 0.00058 19.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC81775.1 - 0.077 12.2 0.0 0.086 12.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC81775.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase NARP1 PF12569.3 EMC81776.1 - 2.6e-216 719.3 23.1 2.6e-216 719.3 16.0 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EMC81776.1 - 7.5e-16 57.2 3.9 0.012 16.1 0.0 8.3 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC81776.1 - 1.8e-15 55.4 23.0 0.00033 20.3 0.1 8.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC81776.1 - 6.7e-15 55.1 16.9 0.0051 17.1 0.3 6.3 3 2 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMC81776.1 - 4.4e-11 42.2 31.3 2.1e-05 24.0 0.3 8.0 6 2 0 7 7 7 3 TPR repeat TPR_16 PF13432.1 EMC81776.1 - 5e-11 42.9 17.9 0.0028 18.2 0.2 6.0 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC81776.1 - 2.4e-09 36.4 23.6 0.002 17.6 0.1 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC81776.1 - 1.5e-08 34.4 18.3 0.024 14.5 0.3 6.9 6 1 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC81776.1 - 2.7e-07 30.6 33.7 0.015 15.4 1.5 7.9 5 3 5 10 10 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMC81776.1 - 8.2e-07 28.3 32.4 0.0022 17.6 0.1 8.7 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMC81776.1 - 8.5e-06 25.5 7.8 0.18 11.6 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMC81776.1 - 0.00032 20.8 0.1 11 6.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC81776.1 - 0.00057 19.4 16.7 0.31 10.9 0.1 7.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC81776.1 - 0.0022 18.3 12.5 11 6.7 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMC81776.1 - 0.013 15.4 0.2 0.013 15.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMC81776.1 - 0.02 13.9 15.5 0.13 11.2 3.1 4.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMC81776.1 - 0.034 13.9 2.6 9 6.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC81776.1 - 0.047 13.9 10.7 16 6.0 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC81776.1 - 0.061 13.2 7.3 20 5.1 0.1 5.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF1674 PF07896.7 EMC81776.1 - 2 8.6 4.8 5.5 7.2 3.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) U79_P34 PF03064.11 EMC81776.1 - 3.2 7.1 12.0 5.4 6.4 8.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ets PF00178.17 EMC81778.1 - 4.3e-35 119.7 2.6 6.8e-35 119.0 1.8 1.3 1 0 0 1 1 1 1 Ets-domain Elf-1_N PF12310.3 EMC81778.1 - 2.1e-33 114.5 2.9 2.1e-33 114.5 2.0 2.7 3 0 0 3 3 3 1 Transcription factor protein N terminal Exo_endo_phos PF03372.18 EMC81779.1 - 2.9e-25 89.6 0.0 3.7e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMC81779.1 - 7.8e-05 22.2 0.0 0.00027 20.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase AA_permease_2 PF13520.1 EMC81780.1 - 2.6e-61 207.4 40.1 3.1e-61 207.2 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC81780.1 - 6.9e-32 110.4 37.9 1.1e-31 109.7 26.3 1.3 1 1 0 1 1 1 1 Amino acid permease PSI_PsaF PF02507.10 EMC81780.1 - 0.11 11.9 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Cadherin PF00028.12 EMC81781.1 - 1.6e-82 271.8 3.1 6.9e-17 61.4 0.0 6.4 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 EMC81781.1 - 4.8e-14 51.6 0.4 1.4e-12 46.9 0.1 3.3 3 0 0 3 3 3 1 Cadherin-like Syndecan PF01034.15 EMC81781.1 - 0.051 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Syndecan domain zf-H2C2_2 PF13465.1 EMC81782.1 - 8.3e-14 51.0 9.0 2.3e-08 33.9 2.0 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC81782.1 - 9.6e-14 50.8 26.4 1.6e-05 24.9 1.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81782.1 - 8.3e-11 41.4 18.2 0.00028 20.9 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EMC81782.1 - 0.0038 17.3 1.6 0.0038 17.3 1.1 2.6 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EMC81782.1 - 0.023 14.8 7.1 1 9.5 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC81782.1 - 1.5 8.8 16.7 1.8 8.5 0.8 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger DC_STAMP PF07782.8 EMC81783.1 - 1.1 8.8 8.0 0.067 12.7 1.9 1.6 2 0 0 2 2 2 0 DC-STAMP-like protein MHC_II_beta PF00969.14 EMC81784.1 - 1.1e-36 124.6 0.1 1.7e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain C1-set PF07654.10 EMC81784.1 - 1.7e-29 101.6 1.0 2.4e-29 101.1 0.7 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC81784.1 - 0.00011 21.9 0.3 0.00019 21.2 0.2 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC81784.1 - 0.0014 18.7 1.1 0.0032 17.5 0.8 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC81784.1 - 0.0024 17.9 0.2 0.0039 17.2 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC81784.1 - 0.0083 15.9 0.1 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain DUF4448 PF14610.1 EMC81784.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) MHC_I PF00129.13 EMC81784.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_3 PF13927.1 EMC81784.1 - 0.13 12.7 1.0 0.31 11.5 0.7 1.6 1 1 0 1 1 1 0 Immunoglobulin domain 7tm_4 PF13853.1 EMC81785.1 - 1.5e-46 157.7 6.4 1.5e-46 157.7 4.5 1.8 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC81785.1 - 5e-17 61.8 7.3 6.3e-17 61.5 5.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) F-box-like PF12937.2 EMC81787.1 - 2.4e-09 36.7 5.7 5.2e-09 35.6 4.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC81787.1 - 2.6e-08 33.2 2.7 6e-08 32.1 1.8 1.6 1 0 0 1 1 1 1 F-box domain Radical_SAM PF04055.16 EMC81788.1 - 1.6e-19 70.6 0.7 1.9e-18 67.1 0.1 2.6 3 1 1 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EMC81788.1 - 5.5e-11 42.3 0.0 1.9e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMC81788.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.20 EMC81789.1 - 2.3e-50 171.1 0.0 1.1e-49 168.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81789.1 - 1.3e-35 122.7 0.2 1.4e-26 93.1 0.0 2.6 1 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EMC81789.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-NADH-PPase PF09297.6 EMC81789.1 - 0.0019 17.6 2.2 0.7 9.4 0.0 2.6 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain YrbL-PhoP_reg PF10707.4 EMC81789.1 - 0.0049 16.2 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL ABC1 PF03109.11 EMC81789.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC1 family APH PF01636.18 EMC81789.1 - 0.078 12.6 0.3 0.63 9.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EMC81789.1 - 0.084 12.2 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Opiods_neuropep PF01160.13 EMC81790.1 - 1e-12 47.6 2.2 1.6e-12 46.9 1.5 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide DUF1272 PF06906.6 EMC81790.1 - 0.012 15.4 1.6 0.019 14.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) HTH_18 PF12833.2 EMC81790.1 - 0.086 12.9 0.3 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PAS_11 PF14598.1 EMC81791.1 - 3.2e-27 94.6 0.0 3.7e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 PAS domain DUF1518 PF07469.7 EMC81792.1 - 4.4e-36 122.8 40.6 6.5e-21 74.2 14.1 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF1518) CENP-O PF09496.5 EMC81793.1 - 6.8e-19 67.9 0.2 6.8e-19 67.9 0.1 2.0 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DASH_Spc19 PF08287.6 EMC81793.1 - 0.024 14.2 2.7 0.044 13.4 1.8 1.4 1 0 0 1 1 1 0 Spc19 Mnd1 PF03962.10 EMC81793.1 - 0.036 13.7 5.7 0.056 13.1 4.0 1.2 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EMC81793.1 - 0.052 13.0 10.0 0.11 11.9 7.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF848 PF05852.6 EMC81793.1 - 0.068 13.0 3.5 0.12 12.2 2.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) FUSC PF04632.7 EMC81793.1 - 0.08 11.3 2.2 8.2 4.7 2.7 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3373 PF11853.3 EMC81793.1 - 0.14 10.6 3.0 0.22 10.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) V_ATPase_I PF01496.14 EMC81793.1 - 0.19 9.5 0.4 0.22 9.3 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EMC81793.1 - 0.32 9.8 4.6 0.62 8.9 3.2 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 EMC81793.1 - 1.6 7.6 6.6 2.4 7.0 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.1 EMC81793.1 - 2 8.2 8.4 3.4 7.5 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) KfrA_N PF11740.3 EMC81793.1 - 2 8.8 20.5 0.21 12.0 10.6 2.0 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term OmpH PF03938.9 EMC81793.1 - 3.9 7.3 11.6 6.7 6.6 8.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ras PF00071.17 EMC81794.1 - 2.2e-42 144.2 0.1 2.8e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81794.1 - 2.4e-16 60.3 0.0 3.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81794.1 - 9.3e-16 57.5 0.0 1.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.26 EMC81794.1 - 2.2e-12 46.5 0.0 3.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain GTP_EFTU PF00009.22 EMC81794.1 - 4.8e-06 26.1 0.0 1.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC81794.1 - 9e-05 21.7 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC81794.1 - 0.00018 21.4 0.0 0.0011 18.9 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC81794.1 - 0.025 13.8 0.0 0.16 11.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B CBF PF03914.12 EMC81796.1 - 0.031 13.7 4.8 1.7 8.0 0.1 3.5 2 2 0 3 3 3 0 CBF/Mak21 family ACTH_domain PF00976.13 EMC81797.1 - 6.2e-25 86.7 4.4 6.2e-25 86.7 3.1 4.1 4 0 0 4 4 4 3 Corticotropin ACTH domain Op_neuropeptide PF08035.6 EMC81797.1 - 3.3e-15 55.3 0.1 6.9e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 Opioids neuropeptide NPP PF08384.5 EMC81797.1 - 2.9e-07 30.0 0.1 2.9e-07 30.0 0.1 1.7 2 0 0 2 2 2 1 Pro-opiomelanocortin, N-terminal region Fibrinogen_C PF00147.13 EMC81798.1 - 3.9e-44 150.9 0.5 4.4e-44 150.8 0.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Stathmin PF00836.14 EMC81799.1 - 4e-76 253.3 22.0 4.7e-76 253.1 15.2 1.0 1 0 0 1 1 1 1 Stathmin family CDC37_N PF03234.9 EMC81799.1 - 0.18 12.0 14.7 0.24 11.7 10.2 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Phage_GPO PF05929.6 EMC81799.1 - 4.5 6.4 9.8 6.3 5.9 6.8 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Asp-B-Hydro_N PF05279.6 EMC81799.1 - 5.2 6.8 14.5 6.1 6.6 10.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Atg14 PF10186.4 EMC81799.1 - 7 5.4 19.2 8.6 5.2 13.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATC_hydrolase PF14196.1 EMC81799.1 - 8.7 6.7 7.8 13 6.1 5.4 1.3 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase PRY PF13765.1 EMC81800.1 - 1.1e-14 53.7 0.0 2.2e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 SPRY-associated domain zf-C3HC4_2 PF13923.1 EMC81800.1 - 4.4e-09 36.2 15.6 4.4e-09 36.2 10.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.23 EMC81800.1 - 7.4e-09 35.7 0.2 1.8e-08 34.5 0.1 1.9 1 1 0 1 1 1 1 SPRY domain zf-B_box PF00643.19 EMC81800.1 - 2.1e-08 33.9 3.4 2.1e-08 33.9 2.4 2.8 2 0 0 2 2 2 1 B-box zinc finger zf-RING_2 PF13639.1 EMC81800.1 - 9.5e-08 31.7 15.6 9.5e-08 31.7 10.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC81800.1 - 1.5e-07 30.9 11.7 1.5e-07 30.9 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC81800.1 - 2.2e-07 30.6 12.9 2.2e-07 30.6 9.0 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EMC81800.1 - 5.4e-07 29.3 3.8 1.1e-06 28.3 2.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EMC81800.1 - 7e-07 28.8 13.8 7e-07 28.8 9.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC81800.1 - 2.2e-05 24.0 14.1 2.2e-05 24.0 9.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC81800.1 - 0.00032 20.3 5.3 0.00032 20.3 3.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EMC81800.1 - 0.00039 20.1 5.0 0.00072 19.2 3.4 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-CHC2 PF01807.15 EMC81800.1 - 0.0058 16.1 1.4 0.0062 16.0 0.1 1.6 1 1 0 1 1 1 1 CHC2 zinc finger U-box PF04564.10 EMC81800.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.1 EMC81800.1 - 1.6 8.4 17.9 0.069 12.7 7.8 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain NYD-SP28 PF14772.1 EMC81801.1 - 4.5e-29 100.6 15.3 4.5e-29 100.6 10.6 5.1 3 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.1 EMC81801.1 - 2.1e-19 68.9 0.5 2.1e-19 68.9 0.4 3.8 3 1 2 5 5 5 2 Sperm tail C-terminal domain Baculo_PEP_C PF04513.7 EMC81801.1 - 4.8 7.0 18.7 1.9 8.3 1.6 3.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hormone_recep PF00104.25 EMC81802.1 - 7.1e-07 28.5 0.1 7.5e-07 28.4 0.1 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Pro_isomerase PF00160.16 EMC81803.1 - 1e-45 155.7 0.3 1.1e-45 155.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CTX_RstB PF07459.6 EMC81804.1 - 0.08 12.8 4.3 24 4.8 0.1 3.2 2 1 1 3 3 3 0 CTX phage RstB protein zf-UDP PF14569.1 EMC81804.1 - 5.6 6.7 6.7 3.3 7.5 0.2 3.1 3 1 1 4 4 4 0 Zinc-binding RING-finger RhoGEF PF00621.15 EMC81805.1 - 3.1e-31 108.6 1.7 3.1e-31 108.6 1.2 2.8 3 0 0 3 3 3 1 RhoGEF domain SH3_2 PF07653.12 EMC81805.1 - 2.7e-18 65.1 0.3 6.6e-18 63.9 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC81805.1 - 1.5e-17 62.8 0.1 3.1e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC81805.1 - 8.3e-17 60.3 0.1 1.5e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EMC81805.1 - 5.4e-10 39.3 0.2 1.6e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 PH domain GlutR_dimer PF00745.15 EMC81805.1 - 0.1 12.5 4.1 0.32 10.9 2.8 1.8 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ank_2 PF12796.2 EMC81806.1 - 7.9e-27 93.4 0.4 2.4e-17 63.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC81806.1 - 6.1e-19 66.8 2.5 1.5e-06 27.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMC81806.1 - 8.8e-17 60.7 1.0 1.5e-08 34.5 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC81806.1 - 2.6e-16 59.6 0.2 9.6e-08 32.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81806.1 - 3.5e-11 42.1 0.2 7.2e-05 22.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat ING PF12998.2 EMC81807.1 - 2.1e-33 114.7 5.8 2.1e-33 114.7 4.0 2.3 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMC81807.1 - 1.6e-10 40.4 8.7 3.8e-10 39.2 6.1 1.7 1 0 0 1 1 1 1 PHD-finger SRP-alpha_N PF04086.8 EMC81807.1 - 0.019 14.3 15.0 0.032 13.6 10.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PHD_2 PF13831.1 EMC81807.1 - 0.028 13.7 3.8 0.052 12.8 2.6 1.4 1 0 0 1 1 1 0 PHD-finger FadA PF09403.5 EMC81807.1 - 0.052 13.5 0.7 0.052 13.5 0.5 2.8 1 1 1 3 3 2 0 Adhesion protein FadA ApoB100_C PF12491.3 EMC81807.1 - 0.069 12.8 0.6 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal DUF4661 PF15576.1 EMC81807.1 - 0.079 12.5 3.4 0.12 12.0 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-HC5HC2H PF13771.1 EMC81807.1 - 0.1 12.7 2.6 0.42 10.7 1.7 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain Hid1 PF12722.2 EMC81807.1 - 0.75 7.4 11.4 0.92 7.1 7.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING-like PF08746.6 EMC81807.1 - 0.92 9.5 6.7 2.1 8.4 4.6 1.7 1 0 0 1 1 1 0 RING-like domain RR_TM4-6 PF06459.7 EMC81807.1 - 6.1 6.6 11.7 9.3 6.0 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_8 PF13855.1 EMC81808.1 - 6.7e-16 57.7 0.0 2.1e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EMC81808.1 - 3.9e-09 35.9 0.0 3.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMC81808.1 - 3.4e-08 32.3 0.2 0.033 14.3 0.0 4.0 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EMC81808.1 - 6.4e-08 31.5 0.1 0.029 14.3 0.0 3.6 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 EMC81808.1 - 1.1e-05 24.9 0.0 1.2 9.4 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_3 PF07725.7 EMC81808.1 - 0.15 11.8 0.6 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat Trypsin PF00089.21 EMC81809.1 - 1.7e-61 207.6 0.1 1.9e-61 207.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMC81809.1 - 0.00053 19.9 0.0 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 EMC81809.1 - 0.0056 16.0 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.21 EMC81811.1 - 2.3e-72 243.1 0.3 2.8e-72 242.8 0.2 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC81811.1 - 4.1e-06 26.2 0.0 0.012 14.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Tim17 PF02466.14 EMC81812.1 - 9.3e-08 32.1 0.1 2.7e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4010 PF13194.1 EMC81812.1 - 0.065 12.5 0.9 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Frizzled PF01534.12 EMC81813.1 - 2.4e-135 450.5 24.3 6.1e-133 442.6 16.8 2.0 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 EMC81813.1 - 8.1e-18 64.8 2.7 1.6e-17 63.9 1.9 1.5 1 0 0 1 1 1 1 Fz domain TctB PF07331.6 EMC81813.1 - 0.016 14.8 0.3 0.016 14.8 0.2 3.4 2 2 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Ndc1_Nup PF09531.5 EMC81813.1 - 7.5 4.8 12.6 0.021 13.2 1.7 1.7 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Trypsin PF00089.21 EMC81814.1 - 5.1e-11 42.5 0.1 3.5e-10 39.8 0.1 2.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMC81814.1 - 2.4e-07 30.7 0.0 4.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain FB_lectin PF07367.6 EMC81814.1 - 0.024 14.2 0.3 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Fungal fruit body lectin Malic_M PF03949.10 EMC81815.1 - 1.1e-94 316.8 0.2 1.3e-94 316.5 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMC81815.1 - 3.6e-80 267.8 0.0 5.3e-80 267.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Peptidase_S28 PF05577.7 EMC81816.1 - 4.6e-98 328.6 0.0 5.4e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EMC81816.1 - 2.8e-05 24.1 0.1 5.2e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 EMC81816.1 - 0.0011 17.5 0.0 0.002 16.6 0.0 1.4 2 0 0 2 2 2 1 PS-10 peptidase S37 Rep_fac-A_C PF08646.5 EMC81817.1 - 1.9e-10 40.5 0.1 3.4e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain FYVE PF01363.16 EMC81817.1 - 0.55 10.1 5.3 1.3 9.0 3.7 1.8 1 1 0 1 1 1 0 FYVE zinc finger Ras PF00071.17 EMC81819.1 - 1.6e-58 196.6 0.0 1.9e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81819.1 - 1.5e-20 73.8 0.0 2.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81819.1 - 3.1e-15 55.8 0.0 4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC81819.1 - 6.2e-10 38.6 0.0 7.5e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC81819.1 - 5.6e-06 25.9 0.0 8e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC81819.1 - 2.4e-05 24.2 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EMC81819.1 - 3.1e-05 23.6 0.8 0.0065 16.0 0.1 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA PF00004.24 EMC81819.1 - 0.00022 21.4 0.0 0.0012 19.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EMC81819.1 - 0.00053 19.3 0.5 0.0044 16.3 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EMC81819.1 - 0.00075 18.7 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EMC81819.1 - 0.0026 17.4 0.1 0.0068 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EMC81819.1 - 0.0027 17.2 0.2 0.016 14.7 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EMC81819.1 - 0.0027 17.8 0.2 0.0068 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EMC81819.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EMC81819.1 - 0.022 14.7 0.2 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EMC81819.1 - 0.049 13.0 0.3 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EMC81819.1 - 0.051 13.2 0.7 0.16 11.5 0.0 2.0 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EMC81819.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EMC81819.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EMC81819.1 - 0.096 11.8 0.0 0.25 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EMC81819.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMC81819.1 - 0.16 11.9 0.7 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain CTD_bind PF04818.8 EMC81820.1 - 7.3e-06 26.1 0.1 2.5e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SHOCT PF09851.4 EMC81820.1 - 0.0032 16.8 1.0 0.01 15.2 0.1 2.2 2 0 0 2 2 2 1 Short C-terminal domain Ank_2 PF12796.2 EMC81821.1 - 1.4e-52 175.9 11.8 1.2e-17 64.0 0.5 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC81821.1 - 3.1e-43 145.3 21.0 1e-09 38.6 0.0 6.9 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 EMC81821.1 - 6.3e-39 129.8 15.4 3.5e-07 29.7 0.1 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EMC81821.1 - 4.5e-35 118.8 17.3 8.5e-11 41.7 0.0 7.5 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC81821.1 - 1.1e-22 77.8 9.0 0.00022 21.1 0.1 8.2 8 0 0 8 8 8 6 Ankyrin repeat DUF4129 PF13559.1 EMC81821.1 - 0.0023 17.8 0.9 0.18 11.8 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4129) AAA_23 PF13476.1 EMC81821.1 - 0.039 14.2 4.4 0.067 13.5 3.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.5 EMC81821.1 - 3.4 7.7 10.5 17 5.5 1.8 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) APG6 PF04111.7 EMC81821.1 - 6.1 5.7 14.1 9.8 5.1 9.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1640 PF07798.6 EMC81822.1 - 7.5e-69 231.2 11.7 8.9e-69 231.0 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Vac_Fusion PF02346.11 EMC81822.1 - 0.014 14.8 2.2 0.046 13.1 0.1 2.7 2 2 0 2 2 2 0 Chordopoxvirus fusion protein DUF3509 PF12021.3 EMC81822.1 - 0.031 13.9 3.2 0.14 11.9 2.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3509) MHC_I_2 PF14586.1 EMC81822.1 - 0.046 13.2 0.2 0.06 12.9 0.1 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 HALZ PF02183.13 EMC81822.1 - 0.049 13.3 1.5 0.076 12.7 0.3 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper RNA_pol_Rpb1_5 PF04998.12 EMC81822.1 - 0.64 9.2 2.9 0.92 8.7 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FlaC_arch PF05377.6 EMC81822.1 - 3.2 7.7 6.2 1.9 8.4 0.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EMC81822.1 - 3.5 8.0 11.3 1.5 9.1 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CemA PF03040.9 EMC81822.1 - 3.7 7.0 10.2 6.2 6.3 0.0 2.9 1 1 2 3 3 3 0 CemA family DUF2175 PF09943.4 EMC81822.1 - 8.7 6.4 9.6 2.8 8.0 2.1 2.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) PDZ PF00595.19 EMC81823.1 - 1.2e-21 76.6 0.6 1.5e-21 76.3 0.4 1.1 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_assoc PF10600.4 EMC81823.1 - 3.1e-19 69.0 0.7 4.2e-19 68.5 0.5 1.2 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.1 EMC81823.1 - 3.7e-06 26.7 0.1 5.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EMC81824.1 - 7.3e-45 151.0 2.1 1.3e-21 76.5 0.2 2.0 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC81824.1 - 1.8e-12 46.9 1.2 6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_assoc PF10600.4 EMC81824.1 - 8.7e-05 22.7 0.9 0.00014 22.0 0.7 1.4 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors L27_1 PF09058.5 EMC81825.1 - 1.1e-13 50.8 0.1 1.5e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 L27_1 DUF1370 PF07114.6 EMC81826.1 - 4e-68 228.3 0.2 4.8e-68 228.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1370) DsbB PF02600.11 EMC81826.1 - 0.1 12.3 4.4 0.44 10.3 0.0 2.7 2 1 1 3 3 3 0 Disulfide bond formation protein DsbB ANTH PF07651.11 EMC81827.1 - 8.8e-81 270.6 0.8 1.2e-80 270.2 0.6 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EMC81827.1 - 2.2e-12 46.9 0.1 4.5e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 ENTH domain DUF3824 PF12868.2 EMC81827.1 - 0.16 12.8 0.2 0.16 12.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) T2SM PF04612.7 EMC81827.1 - 0.31 10.8 2.5 0.58 9.9 1.7 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M EF-1_beta_acid PF10587.4 EMC81827.1 - 0.77 9.9 5.4 1.6 8.9 3.8 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_60s PF00428.14 EMC81827.1 - 7.7 6.9 7.6 15 6.0 0.7 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.27 EMC81828.1 - 1.3e-14 53.4 6.7 3.8e-06 26.5 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EMC81828.1 - 0.0062 14.7 0.0 0.0099 14.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Lipoprotein_3 PF00938.12 EMC81828.1 - 0.07 12.8 1.1 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein DUF775 PF05603.7 EMC81829.1 - 1.1e-54 185.0 0.6 1.4e-54 184.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ANTH PF07651.11 EMC81829.1 - 0.071 11.8 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 ANTH domain MRAP PF15183.1 EMC81830.1 - 7.9e-34 115.1 0.1 1.2e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family CCDC92 PF14916.1 EMC81831.1 - 0.0027 17.2 5.4 0.0027 17.2 3.8 7.9 7 1 0 7 7 7 2 Coiled-coil domain of unknown function T-box PF00907.17 EMC81832.1 - 7.4e-86 286.3 0.0 1.2e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 T-box 5_nucleotid_C PF02872.13 EMC81833.1 - 9.7e-38 129.5 0.0 1.8e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EMC81833.1 - 7.7e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PXA PF02194.10 EMC81834.1 - 8.6e-43 146.0 1.0 1.4e-42 145.3 0.1 1.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EMC81834.1 - 1.6e-25 89.3 0.1 8.3e-25 87.0 0.0 2.3 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EMC81834.1 - 2.3e-20 72.4 1.1 2.3e-20 72.4 0.7 2.8 3 0 0 3 3 3 1 PX domain RGS PF00615.14 EMC81834.1 - 2.5e-12 46.9 4.9 5e-12 45.9 1.2 2.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain 7tm_1 PF00001.16 EMC81835.1 - 1e-79 267.2 12.6 1.4e-79 266.9 8.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81835.1 - 5.2e-07 29.0 14.0 1.3e-06 27.7 9.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC81835.1 - 1.4e-06 27.6 14.0 2.7e-06 26.7 9.7 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CytochromB561_N PF09786.4 EMC81835.1 - 0.21 10.0 4.5 5.5 5.3 1.6 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal Hormone_6 PF00236.13 EMC81836.1 - 1.5e-54 181.7 8.9 1.8e-54 181.5 6.2 1.0 1 0 0 1 1 1 1 Glycoprotein hormone PDGF PF00341.12 EMC81836.1 - 0.065 13.3 9.6 0.12 12.4 6.6 1.5 1 1 0 1 1 1 0 PDGF/VEGF domain Connexin PF00029.14 EMC81837.1 - 2e-45 153.2 0.9 3.6e-45 152.4 0.6 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC81837.1 - 2.2e-28 97.8 6.1 7e-28 96.2 4.2 1.9 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF3816 PF12822.2 EMC81837.1 - 0.68 9.7 6.5 17 5.2 4.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Nuc_sug_transp PF04142.10 EMC81839.1 - 5.2e-95 317.1 15.5 6e-95 316.9 10.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EMC81839.1 - 1.9e-09 36.8 16.3 2.5e-09 36.4 11.3 1.1 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EMC81839.1 - 4.1e-05 23.7 0.7 4.1e-05 23.7 0.5 2.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC81839.1 - 9.4e-05 22.4 21.9 0.00032 20.7 1.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EMC81839.1 - 0.00012 21.7 22.0 0.023 14.3 0.8 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF3963 PF13124.1 EMC81839.1 - 0.099 12.4 1.6 0.33 10.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) DUF2839 PF10999.3 EMC81839.1 - 5.6 7.0 7.7 0.62 10.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) tRNA-synt_1d PF00750.14 EMC81840.1 - 9.9e-73 244.9 1.8 1.5e-72 244.4 1.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EMC81840.1 - 3e-20 72.3 0.6 3e-20 72.3 0.4 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1g PF09334.6 EMC81840.1 - 0.03 12.9 0.8 0.65 8.5 0.1 2.3 1 1 1 2 2 2 0 tRNA synthetases class I (M) Arg_tRNA_synt_N PF03485.11 EMC81840.1 - 0.039 14.5 0.4 1.1 9.7 0.0 3.1 3 1 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain NPHI_C PF08469.5 EMC81840.1 - 0.21 11.4 2.6 8 6.3 0.0 2.7 1 1 1 2 2 2 0 Nucleoside triphosphatase I C-terminal ORC3_N PF07034.6 EMC81841.1 - 8e-127 422.7 9.4 8e-127 422.7 6.5 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus TAFH PF07531.9 EMC81841.1 - 0.012 15.2 4.1 2 8.1 0.1 3.9 3 0 0 3 3 3 0 NHR1 homology to TAF DUF3156 PF11354.3 EMC81841.1 - 0.037 13.3 0.0 0.094 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) DUF885 PF05960.6 EMC81842.1 - 0.018 14.1 0.1 0.019 14.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Nnf1 PF03980.9 EMC81842.1 - 0.032 14.2 0.6 5.3 7.0 0.1 2.2 2 0 0 2 2 2 0 Nnf1 HMG_box PF00505.14 EMC81842.1 - 0.16 12.2 2.1 0.19 12.0 0.0 2.0 2 1 0 2 2 2 0 HMG (high mobility group) box DUF930 PF06059.7 EMC81843.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) DUF21 PF01595.15 EMC81843.1 - 0.047 12.9 0.5 0.051 12.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF21 CENP-C_C PF11699.3 EMC81843.1 - 0.13 12.3 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like 7tm_1 PF00001.16 EMC81844.1 - 1.3e-50 171.9 17.6 1.9e-50 171.4 12.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81844.1 - 1.6e-12 47.1 16.9 2.4e-12 46.5 11.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC81844.1 - 2.4e-05 23.5 11.0 2.4e-05 23.5 7.6 2.0 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Flavi_NS4B PF01349.12 EMC81844.1 - 0.0026 16.7 0.1 0.0049 15.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus non-structural protein NS4B mRNA_cap_C PF03919.10 EMC81845.1 - 3.2e-22 78.8 0.4 4.2e-22 78.4 0.3 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain V-set PF07686.12 EMC81846.1 - 3.3e-09 36.6 0.0 4.7e-09 36.1 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC81846.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain UCH PF00443.24 EMC81847.1 - 1.4e-19 70.2 1.2 2.7e-19 69.3 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC81847.1 - 1.5e-06 27.8 2.9 1.5e-06 27.8 2.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Sad1_UNC PF07738.8 EMC81848.1 - 2.1e-36 124.6 0.0 2.9e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal 7tm_4 PF13853.1 EMC81849.1 - 4.8e-43 146.4 4.2 5.8e-43 146.1 2.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC81849.1 - 0.00015 21.0 2.6 0.0002 20.6 1.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NhaB PF06450.7 EMC81849.1 - 0.006 15.2 0.5 0.0071 15.0 0.3 1.1 1 0 0 1 1 1 1 Bacterial Na+/H+ antiporter B (NhaB) BCD PF15461.1 EMC81849.1 - 0.079 12.3 2.9 0.1 11.9 2.0 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase TMEMspv1-c74-12 PF11044.3 EMC81849.1 - 0.089 12.3 3.6 0.2 11.2 1.4 2.0 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4519 PF15012.1 EMC81849.1 - 0.092 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) VWD PF00094.20 EMC81850.1 - 1.3e-10 41.7 3.1 2.2e-10 40.9 2.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain TILa PF12714.2 EMC81850.1 - 7.3e-10 38.4 13.6 7.3e-10 38.4 9.4 1.8 1 1 1 2 2 2 1 TILa domain VWC PF00093.13 EMC81850.1 - 5.3e-05 23.2 10.8 5.3e-05 23.2 7.5 1.7 2 0 0 2 2 2 1 von Willebrand factor type C domain MLANA PF14991.1 EMC81851.1 - 0.0013 18.7 0.0 0.0016 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein melan-A Adeno_E3_CR2 PF02439.10 EMC81851.1 - 0.015 14.8 1.1 0.024 14.1 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IncA PF04156.9 EMC81851.1 - 0.05 13.1 1.0 0.15 11.6 0.6 1.7 1 1 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 EMC81851.1 - 0.092 13.1 0.4 0.12 12.7 0.2 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMC81851.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator V-set PF07686.12 EMC81852.1 - 4e-06 26.6 0.0 4.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 EMC81852.1 - 0.00068 19.4 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC81852.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC81852.1 - 0.0018 18.3 0.0 0.021 14.9 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 EMC81852.1 - 0.0087 16.1 0.1 0.58 10.3 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain Herpes_gE PF02480.11 EMC81852.1 - 0.13 10.4 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ets PF00178.17 EMC81855.1 - 6.4e-39 131.9 3.1 7.6e-39 131.7 2.1 1.1 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 EMC81855.1 - 0.0079 16.3 0.8 0.01 15.9 0.6 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding WRW PF10206.4 EMC81855.1 - 0.055 13.5 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f DUF2172 PF09940.4 EMC81855.1 - 0.12 10.7 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) RhoGEF PF00621.15 EMC81856.1 - 1.7e-41 142.0 5.3 3e-41 141.2 3.7 1.4 1 0 0 1 1 1 1 RhoGEF domain Toxin_52 PF15605.1 EMC81858.1 - 0.24 11.2 3.4 2.3 8.1 0.1 3.2 1 1 3 4 4 4 0 Putative toxin 52 PT PF04886.7 EMC81859.1 - 7.4e-07 28.3 20.4 0.021 14.1 0.7 5.2 1 1 2 3 3 3 3 PT repeat GST_C_3 PF14497.1 EMC81860.1 - 2.1e-19 69.8 0.0 4.8e-19 68.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC81860.1 - 5.7e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EMC81860.1 - 0.002 18.3 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.1 EMC81860.1 - 0.006 16.7 0.0 0.15 12.3 0.0 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.1 EMC81861.1 - 9.1e-22 77.4 0.0 1.3e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC81861.1 - 5.7e-18 65.2 0.0 1.3e-17 64.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC81861.1 - 1.4e-15 57.2 0.0 1.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC81861.1 - 3.1e-14 53.2 0.0 5.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC81861.1 - 9.1e-12 45.5 0.0 1.4e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMC81861.1 - 1.4e-07 30.8 0.0 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EMC81861.1 - 1.2e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC81861.1 - 6.1e-06 25.5 0.0 8.5e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMC81861.1 - 4e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMC81861.1 - 4.7e-05 22.6 0.0 8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EMC81861.1 - 6.5e-05 22.4 0.0 9.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EMC81861.1 - 7e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMC81861.1 - 0.00065 18.4 0.0 0.00097 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 EMC81861.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.7 EMC81861.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase UCH PF00443.24 EMC81863.1 - 3.9e-49 167.1 1.3 6.5e-49 166.4 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC81863.1 - 5.3e-18 64.8 6.0 5.3e-18 64.8 4.1 2.7 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC81863.1 - 2.2e-14 53.5 7.4 7.6e-12 45.2 5.1 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase THOC7 PF05615.8 EMC81863.1 - 0.0048 17.1 0.4 0.014 15.6 0.3 1.7 1 0 0 1 1 1 1 Tho complex subunit 7 Cyclin_N PF00134.18 EMC81864.1 - 9.6e-15 54.2 2.9 1e-12 47.7 0.5 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC81864.1 - 0.00093 19.1 1.0 0.028 14.3 0.0 2.8 1 1 1 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 EMC81864.1 - 0.01 15.6 0.2 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat 7tm_1 PF00001.16 EMC81865.1 - 4.2e-48 163.7 21.2 5.2e-48 163.4 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4212 PF13937.1 EMC81865.1 - 2.6 8.1 7.8 15 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) SIM_C PF06621.7 EMC81866.1 - 8.1e-123 409.6 18.0 1.2e-122 409.1 12.5 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.6 EMC81866.1 - 6.5e-24 83.8 1.9 1.7e-17 63.2 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EMC81866.1 - 1.8e-21 76.1 1.0 1e-15 57.6 0.1 2.9 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 EMC81866.1 - 2.5e-18 65.9 0.0 5.8e-12 45.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 EMC81866.1 - 2.1e-06 27.3 0.7 3.8e-05 23.2 0.5 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EMC81866.1 - 4.5e-05 23.7 0.0 0.21 11.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMC81866.1 - 0.00043 20.2 0.0 0.025 14.6 0.0 2.7 3 0 0 3 3 3 1 PAS fold SRCR PF00530.13 EMC81867.1 - 6.9e-56 186.7 15.9 2e-33 114.6 5.2 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC81867.1 - 1.7e-10 41.0 3.2 1.8e-05 24.8 0.2 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 EMC81867.1 - 0.056 13.6 0.3 5.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Hepsin, SRCR DUF3027 PF11228.3 EMC81867.1 - 0.32 10.6 4.0 2.7 7.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) PXA PF02194.10 EMC81868.1 - 8.4e-31 106.9 0.0 3.6e-30 104.9 0.0 2.2 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EMC81868.1 - 3.3e-24 85.1 0.8 1.7e-23 82.8 0.3 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EMC81868.1 - 5e-19 68.1 0.2 1.2e-18 66.9 0.1 1.6 1 0 0 1 1 1 1 PX domain DUF2448 PF10476.4 EMC81868.1 - 0.029 13.8 0.2 0.075 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) ADAM_spacer1 PF05986.9 EMC81869.1 - 2.8e-23 81.9 0.0 6.1e-23 80.8 0.0 1.6 1 1 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 EMC81869.1 - 5e-21 75.2 0.0 5e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 EMC81869.1 - 7.1e-13 48.9 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC81869.1 - 2.2e-09 37.8 0.0 4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.14 EMC81869.1 - 7e-09 35.6 33.8 6.7e-07 29.3 2.3 5.6 4 1 0 4 4 4 2 Thrombospondin type 1 domain Reprolysin_2 PF13574.1 EMC81869.1 - 3.3e-06 27.2 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC81869.1 - 4.5e-06 26.3 0.0 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.9 EMC81870.1 - 7.7e-23 80.5 0.0 1.1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 EMC81870.1 - 2.8e-19 69.4 0.0 5.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 EMC81870.1 - 1.3e-11 45.0 0.0 1.3e-11 45.0 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC81870.1 - 9.5e-10 38.7 0.1 1.7e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.14 EMC81870.1 - 2e-08 34.2 16.7 2.3e-06 27.6 0.8 5.2 5 0 0 5 5 5 2 Thrombospondin type 1 domain Reprolysin_4 PF13583.1 EMC81870.1 - 4.2e-08 32.9 0.0 7.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC81870.1 - 2.5e-07 30.9 0.0 4.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC81870.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin BTB PF00651.26 EMC81871.1 - 1.9e-29 101.8 0.7 3.3e-29 101.0 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 EMC81871.1 - 4.1e-18 64.5 24.1 0.00016 21.8 0.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81871.1 - 2.4e-16 58.7 19.3 0.00021 21.3 0.6 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC81871.1 - 8.6e-14 51.0 23.3 2.5e-06 27.4 0.2 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMC81871.1 - 8.8e-11 41.3 14.6 0.0045 16.8 0.1 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EMC81871.1 - 4e-10 39.5 19.9 0.023 14.8 0.2 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC81871.1 - 4.4e-09 36.2 10.1 0.043 13.9 0.0 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC81871.1 - 9.5e-05 22.4 13.0 0.31 11.1 1.8 4.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Glyco_transf_10 PF00852.14 EMC81871.1 - 0.0051 15.4 1.0 0.059 11.9 0.2 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) DUF3342 PF11822.3 EMC81871.1 - 0.17 10.9 6.7 0.39 9.8 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) Zn_Tnp_IS1595 PF12760.2 EMC81871.1 - 0.18 11.6 19.8 0.074 12.8 2.6 3.4 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMC81871.1 - 0.38 10.7 17.0 0.54 10.2 2.0 4.6 3 1 1 4 4 4 0 Zinc ribbon domain zf-TFIIB PF13453.1 EMC81871.1 - 0.88 8.8 8.5 0.22 10.7 0.7 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger DUF678 PF05077.7 EMC81871.1 - 0.95 9.4 6.8 0.33 10.9 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF678) CpXC PF14353.1 EMC81871.1 - 2.7 7.9 9.7 68 3.4 0.3 3.7 1 1 1 2 2 2 0 CpXC protein LIM PF00412.17 EMC81871.1 - 3.2 7.8 12.5 0.56 10.3 3.8 3.2 3 1 0 3 3 3 0 LIM domain C1_1 PF00130.17 EMC81871.1 - 4.6 7.0 10.0 0.94 9.2 2.4 2.9 2 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_4 PF13717.1 EMC81871.1 - 5.8 6.7 12.8 16 5.2 0.1 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Trypsin PF00089.21 EMC81872.1 - 1.3e-66 224.3 0.3 2.4e-66 223.4 0.2 1.5 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 EMC81872.1 - 2.8e-37 126.3 75.0 3e-10 39.8 10.9 4.6 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A CUB PF00431.15 EMC81872.1 - 2.9e-36 123.8 0.2 1.3e-19 70.3 0.1 2.6 2 0 0 2 2 2 2 CUB domain SEA PF01390.15 EMC81872.1 - 2.1e-18 65.9 0.4 5.8e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 SEA domain DUF1986 PF09342.6 EMC81872.1 - 1.1e-06 28.1 0.0 2.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB_2 PF02408.15 EMC81872.1 - 0.00013 21.4 1.7 0.0017 17.8 0.2 2.5 2 0 0 2 2 2 1 CUB-like domain PepSY_TM PF03929.11 EMC81872.1 - 0.076 13.4 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 PepSY-associated TM helix NFRKB_winged PF14465.1 EMC81873.1 - 9e-35 118.5 0.6 8.2e-34 115.4 1.0 2.3 2 0 0 2 2 2 1 NFRKB Winged Helix-like ATP-synt_E PF05680.7 EMC81873.1 - 0.87 9.5 6.9 1.4 8.9 1.8 2.7 2 0 0 2 2 2 0 ATP synthase E chain zf-C2H2 PF00096.21 EMC81874.1 - 1.3e-30 103.8 79.8 0.0004 20.5 1.9 10.9 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC81874.1 - 1.4e-24 84.5 66.0 0.0089 16.2 2.9 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC81874.1 - 8.6e-17 60.5 67.7 0.0016 18.6 1.0 11.8 11 1 0 11 11 11 8 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC81874.1 - 2.5e-15 56.1 55.7 0.00071 19.6 0.0 10.1 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC81874.1 - 4.4e-10 39.1 45.7 0.012 15.4 0.4 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC81874.1 - 1.5e-08 34.6 46.6 0.22 11.6 0.2 9.5 5 2 4 9 9 9 6 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC81874.1 - 7.7e-06 25.9 2.5 0.0022 18.1 0.0 9.2 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC81874.1 - 7.9e-05 22.7 41.7 0.051 13.7 1.5 7.7 7 1 1 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 EMC81874.1 - 0.34 9.3 37.7 0.21 10.0 0.7 6.8 5 2 2 7 7 7 0 Protein of unknown function (DUF629) APP_E2 PF12925.2 EMC81875.1 - 9e-73 243.9 18.7 2.2e-72 242.7 12.9 1.7 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.11 EMC81875.1 - 1.1e-41 140.9 0.8 1.1e-41 140.9 0.5 2.7 3 0 0 3 3 3 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.4 EMC81875.1 - 2.1e-30 104.6 0.8 6.6e-30 103.1 0.2 2.3 2 0 0 2 2 2 1 beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.2 EMC81875.1 - 1.5e-27 95.8 6.4 1.5e-27 95.8 4.5 2.8 3 0 0 3 3 3 1 Copper-binding of amyloid precursor, CuBD Kunitz_BPTI PF00014.18 EMC81875.1 - 1.5e-19 69.9 5.4 1.5e-19 69.9 3.8 2.0 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF716 PF04819.7 EMC81876.1 - 5.2e-34 116.6 1.4 5.2e-34 116.6 0.9 2.0 2 1 0 2 2 2 1 Family of unknown function (DUF716) DUF716 PF04819.7 EMC81877.1 - 1.2e-40 138.0 9.9 2e-40 137.3 6.9 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF716) Homeobox PF00046.24 EMC81878.1 - 4.6e-21 74.1 3.3 4.6e-21 74.1 2.3 1.8 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 EMC81878.1 - 0.032 13.2 0.9 0.061 12.3 0.6 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MDFI PF15316.1 EMC81879.1 - 2.4e-57 193.7 56.0 2.8e-57 193.5 38.8 1.0 1 0 0 1 1 1 1 MyoD family inhibitor HLH PF00010.21 EMC81880.1 - 5e-16 58.1 0.6 8.9e-16 57.3 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3371 PF11851.3 EMC81880.1 - 4.2e-08 33.9 0.6 1.9e-07 31.8 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3371) DUF3735 PF12537.3 EMC81880.1 - 0.03 14.3 0.7 2.3 8.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) 5-FTHF_cyc-lig PF01812.15 EMC81880.1 - 0.12 12.1 1.5 0.15 11.7 1.0 1.2 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family DDRGK PF09756.4 EMC81880.1 - 1.6 8.1 7.6 4.1 6.7 5.2 1.6 1 1 0 1 1 1 0 DDRGK domain Asp PF00026.18 EMC81881.1 - 4.7e-45 154.1 0.4 5.2e-45 154.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC81881.1 - 6.2e-07 29.5 0.9 1.2e-06 28.6 0.6 1.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC81881.1 - 7.3e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease LIM PF00412.17 EMC81882.1 - 6.3e-21 74.1 27.9 6.2e-12 45.4 2.5 3.7 3 1 0 3 3 3 2 LIM domain PET PF06297.9 EMC81882.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 PET Domain UCH PF00443.24 EMC81883.1 - 5.7e-63 212.5 1.2 1.1e-62 211.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC81883.1 - 5e-21 74.5 6.9 5e-21 74.5 4.8 2.7 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC81883.1 - 2.1e-19 70.0 7.9 2.5e-15 56.7 0.2 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase APH PF01636.18 EMC81883.1 - 0.1 12.3 1.8 0.19 11.4 1.3 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3069 PF11269.3 EMC81883.1 - 0.12 12.4 1.8 0.39 10.7 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) DUF2955 PF11168.3 EMC81883.1 - 0.26 10.9 0.0 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) ArfGap PF01412.13 EMC81883.1 - 0.74 9.6 6.7 0.23 11.2 1.8 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Med20 PF08612.6 EMC81884.1 - 1.2e-35 122.6 0.0 1.5e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Bromo_TP PF07524.8 EMC81885.1 - 1.9e-30 104.4 0.7 5e-30 103.0 0.2 1.8 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.4 EMC81885.1 - 7.9e-25 86.6 1.6 1.8e-24 85.5 1.1 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term CENP-S PF15630.1 EMC81885.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EMC81885.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3090 PF11290.3 EMC81885.1 - 0.028 13.8 0.3 0.088 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) CBFD_NFYB_HMF PF00808.18 EMC81885.1 - 0.037 14.0 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EMC81885.1 - 0.093 12.6 0.3 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) BTG PF07742.7 EMC81886.1 - 4.1e-44 148.9 0.0 4.8e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 BTG family LRR_8 PF13855.1 EMC81887.1 - 2.4e-33 113.6 22.1 1.6e-10 40.5 1.2 6.0 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EMC81887.1 - 6.5e-26 89.4 26.0 1.2e-06 27.9 0.1 7.4 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC81887.1 - 1.4e-25 85.4 23.2 0.0085 15.9 0.1 11.3 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 EMC81887.1 - 8.9e-16 56.1 22.4 0.24 11.5 0.3 10.8 9 1 2 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 EMC81887.1 - 5.8e-15 52.7 22.8 0.5 10.7 0.3 10.8 10 1 1 11 11 11 4 Leucine rich repeat LRR_9 PF14580.1 EMC81887.1 - 6.8e-08 32.2 0.4 0.042 13.4 0.1 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.1 EMC81887.1 - 4.2e-07 29.7 3.0 1.5e-05 24.7 0.0 2.6 2 2 0 2 2 2 1 Leucine rich repeats (6 copies) LRRNT PF01462.13 EMC81887.1 - 1.7e-06 27.3 2.2 1.7e-06 27.3 1.5 3.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain FNIP PF05725.7 EMC81887.1 - 5.4e-06 26.2 1.1 0.097 12.6 0.0 4.6 2 2 1 3 3 3 2 FNIP Repeat LRR_4 PF12799.2 EMC81888.1 - 1e-12 47.3 10.7 6e-06 25.7 1.6 3.6 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC81888.1 - 5.3e-10 38.8 11.6 5.2e-05 22.9 5.3 3.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EMC81888.1 - 8.2e-08 31.2 13.2 0.11 12.5 0.6 4.7 4 1 0 4 4 4 4 Leucine Rich Repeat LRR_6 PF13516.1 EMC81888.1 - 1.3e-07 30.9 6.9 0.2 11.7 0.0 4.5 4 1 0 4 4 4 3 Leucine Rich repeat LRR_7 PF13504.1 EMC81888.1 - 1.5e-06 27.4 9.9 0.65 10.4 0.4 4.6 4 1 0 4 4 4 3 Leucine rich repeat DUF3311 PF11755.3 EMC81890.1 - 0.013 15.0 0.1 0.016 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Choline_kinase PF01633.15 EMC81893.1 - 5.4e-57 192.7 0.0 7.8e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EMC81893.1 - 6.8e-16 58.7 0.1 8.6e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMC81893.1 - 0.00024 20.3 1.7 0.00074 18.7 1.2 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Caps_assemb_Wzi PF14052.1 EMC81893.1 - 0.005 15.7 0.3 0.0063 15.4 0.2 1.1 1 0 0 1 1 1 1 Capsule assembly protein Wzi Asp PF00026.18 EMC81894.1 - 8.9e-16 58.0 0.1 1e-15 57.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease A1_Propeptide PF07966.7 EMC81894.1 - 2.1e-06 27.2 0.2 3.9e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 A1 Propeptide TAXi_N PF14543.1 EMC81894.1 - 3.8e-05 23.7 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Got1 PF04178.7 EMC81895.1 - 3.6e-18 65.7 17.7 4e-18 65.6 12.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family PP1c_bdg PF10488.4 EMC81896.1 - 3.6e-67 226.7 22.2 2.6e-66 223.9 15.4 1.9 1 1 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region VEFS-Box PF09733.4 EMC81896.1 - 4.3 6.9 11.0 8.7 5.9 1.3 2.2 2 0 0 2 2 2 0 VEFS-Box of polycomb protein PI3_PI4_kinase PF00454.22 EMC81897.1 - 9.5e-56 188.8 0.5 1.4e-55 188.3 0.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PX PF00787.19 EMC81897.1 - 2.2e-17 62.8 0.0 4.6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 PX domain C2 PF00168.25 EMC81897.1 - 2.7e-15 55.9 0.0 4.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF4135 PF13575.1 EMC81897.1 - 0.023 13.6 0.0 0.054 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) zf-C3HC4_3 PF13920.1 EMC81898.1 - 7e-09 35.2 6.1 7e-09 35.2 4.2 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 EMC81898.1 - 7.9e-06 24.8 8.1 7.9e-06 24.8 5.6 3.0 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 EMC81898.1 - 0.00017 21.5 7.4 0.00017 21.5 5.1 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF596 PF04591.7 EMC81898.1 - 0.028 14.3 0.0 31 4.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF596 DZR PF12773.2 EMC81898.1 - 0.54 10.1 17.1 0.81 9.5 1.4 2.8 2 1 1 3 3 3 0 Double zinc ribbon LRR_8 PF13855.1 EMC81899.1 - 1.3e-50 168.9 36.1 2.6e-13 49.5 1.2 6.5 3 1 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EMC81899.1 - 2.9e-27 93.7 45.7 5.1e-06 25.9 0.3 8.3 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC81899.1 - 7.1e-23 80.7 0.0 1.2e-08 34.7 0.0 2.8 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) I-set PF07679.11 EMC81899.1 - 4e-15 55.4 0.0 6.9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 EMC81899.1 - 3.9e-12 44.4 38.7 0.048 13.6 0.1 12.5 13 0 0 13 13 13 4 Leucine Rich Repeat Ig_2 PF13895.1 EMC81899.1 - 2.8e-09 36.9 0.0 6.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 EMC81899.1 - 6.4e-09 35.5 11.1 0.0081 15.7 0.5 4.7 1 1 4 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.1 EMC81899.1 - 2.8e-08 33.0 26.4 0.41 10.8 0.1 11.2 9 3 3 12 12 12 3 Leucine Rich repeat V-set PF07686.12 EMC81899.1 - 5e-07 29.6 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC81899.1 - 2.4e-06 27.9 0.0 8.3e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 EMC81899.1 - 3.1e-06 26.4 32.8 1 9.8 0.1 11.8 11 1 1 12 12 12 1 Leucine rich repeat ig PF00047.20 EMC81899.1 - 0.0008 19.4 0.1 0.0042 17.1 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.16 EMC81899.1 - 0.11 12.6 0.4 0.22 11.6 0.3 1.4 1 0 0 1 1 1 0 Fibronectin type III domain FAD_binding_7 PF03441.9 EMC81901.1 - 4.3e-101 337.7 0.6 5.7e-101 337.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMC81901.1 - 4.3e-38 130.6 0.0 1.6e-37 128.7 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase UQ_con PF00179.21 EMC81902.1 - 1.3e-35 121.8 0.0 1.7e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC81902.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC81902.1 - 0.0031 17.3 0.3 0.0061 16.4 0.2 1.5 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC81902.1 - 0.02 14.6 0.3 0.038 13.6 0.2 1.5 1 1 0 1 1 1 0 UEV domain Tetraspannin PF00335.15 EMC81903.1 - 6.5e-15 55.0 8.6 7.1e-15 54.8 6.0 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF3098 PF11297.3 EMC81903.1 - 0.044 13.5 0.7 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Sensor PF13796.1 EMC81903.1 - 0.054 13.0 7.8 0.073 12.6 5.4 1.2 1 0 0 1 1 1 0 Putative sensor DUF3681 PF12442.3 EMC81903.1 - 0.056 13.6 2.0 0.069 13.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) DUF1469 PF07332.6 EMC81903.1 - 0.41 10.3 8.6 0.53 10.0 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF872 PF05915.7 EMC81903.1 - 3 7.7 7.5 8.2 6.3 0.4 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) YiaAB PF05360.9 EMC81903.1 - 3 7.4 10.5 0.9 9.1 1.0 2.4 2 0 0 2 2 2 0 yiaA/B two helix domain HlyIII PF03006.15 EMC81904.1 - 6.3e-69 231.7 21.5 7.7e-69 231.4 14.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4405 PF14358.1 EMC81904.1 - 0.0076 16.3 2.2 0.0076 16.3 1.5 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF4405) NfeD PF01957.13 EMC81904.1 - 0.06 13.4 0.1 0.06 13.4 0.1 3.0 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF962 PF06127.6 EMC81904.1 - 2 8.3 9.0 0.066 13.1 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF4131 PF13567.1 EMC81904.1 - 7.8 5.8 20.1 0.73 9.2 3.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Tim17 PF02466.14 EMC81905.1 - 5.5e-35 120.2 4.0 6.5e-35 119.9 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tropomodulin PF03250.9 EMC81906.1 - 2.9e-05 23.6 15.6 2.9e-05 23.6 10.8 2.1 2 1 0 2 2 2 1 Tropomodulin LRR_6 PF13516.1 EMC81906.1 - 0.1 12.7 1.3 0.38 10.9 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeat Borrelia_P83 PF05262.6 EMC81906.1 - 0.2 9.8 30.3 0.26 9.5 21.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 EMC81906.1 - 0.53 8.6 45.4 0.72 8.2 31.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 EMC81906.1 - 0.79 7.8 43.7 1.4 7.0 30.3 1.3 1 0 0 1 1 1 0 Utp14 protein LMBR1 PF04791.11 EMC81906.1 - 6.9 5.1 6.3 14 4.0 4.3 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Shisa PF13908.1 EMC81907.1 - 2.8e-11 43.9 28.8 2.8e-11 43.9 20.0 2.8 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator 7tm_1 PF00001.16 EMC81908.1 - 3.7e-52 177.0 9.9 4.4e-52 176.7 6.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC81908.1 - 0.021 13.9 2.8 0.09 11.8 1.9 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 EMC81908.1 - 0.028 13.5 8.2 0.42 9.7 5.7 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1151 PF06625.6 EMC81909.1 - 1.2e-13 50.8 0.3 6.5e-13 48.4 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1151) Cadherin PF00028.12 EMC81910.1 - 8e-130 423.4 10.2 8.7e-23 80.3 0.0 6.1 6 0 0 6 6 6 6 Cadherin domain Cadherin_pro PF08758.6 EMC81910.1 - 0.00013 21.6 0.0 1.1 9.1 0.0 3.9 3 1 0 3 3 3 2 Cadherin prodomain like Cadherin_2 PF08266.7 EMC81910.1 - 0.008 15.7 0.0 30 4.2 0.0 4.7 5 0 0 5 5 5 1 Cadherin-like Pro_isomerase PF00160.16 EMC81911.1 - 2.3e-47 161.0 0.0 2.6e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.15 EMC81912.1 - 2.7e-127 424.6 2.5 3e-127 424.5 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC81912.1 - 2.6e-14 52.8 0.4 5.3e-13 48.5 0.0 2.7 2 1 1 3 3 3 1 ADP-ribosylation factor family Miro PF08477.8 EMC81912.1 - 0.0012 19.3 0.7 1 9.8 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein G-alpha PF00503.15 EMC81913.1 - 8.9e-132 439.4 0.7 1e-131 439.2 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC81913.1 - 1.9e-16 59.8 1.9 3.9e-11 42.5 0.2 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC81913.1 - 0.00049 19.3 0.2 0.17 10.9 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF2951 PF11166.3 EMC81913.1 - 0.0088 15.8 0.5 0.047 13.5 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2951) AAA_29 PF13555.1 EMC81913.1 - 0.038 13.5 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 EMC81913.1 - 0.041 12.8 0.6 0.072 12.0 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 A_deaminase PF00962.17 EMC81914.1 - 5.2e-120 400.3 1.7 7.7e-120 399.7 1.2 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase PTB PF08416.8 EMC81915.1 - 6.1e-14 52.0 0.1 9.4e-14 51.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain CSF-1 PF05337.6 EMC81916.1 - 0.001 18.5 0.5 0.0028 17.0 0.0 1.9 3 0 0 3 3 3 1 Macrophage colony stimulating factor-1 (CSF-1) YolD PF08863.5 EMC81916.1 - 0.18 11.6 1.8 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 YolD-like protein AdoHcyase PF05221.12 EMC81917.1 - 4.3e-115 383.2 0.0 1.4e-70 237.3 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EMC81917.1 - 1.2e-81 272.2 2.3 1.9e-81 271.6 1.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMC81917.1 - 1.8e-09 36.9 0.0 3.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EMC81917.1 - 4.4e-05 22.9 0.1 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain THF_DHG_CYH_C PF02882.14 EMC81917.1 - 0.00018 20.6 1.3 0.00067 18.7 0.9 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EMC81917.1 - 0.0007 19.8 0.6 0.0031 17.7 0.5 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EMC81917.1 - 0.00082 19.4 0.5 0.0029 17.7 0.3 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMC81917.1 - 0.0023 17.9 0.3 0.0081 16.1 0.2 2.0 1 1 0 1 1 1 1 TrkA-N domain Malic_M PF03949.10 EMC81917.1 - 0.003 17.1 0.9 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.16 EMC81917.1 - 0.0096 15.5 3.1 0.08 12.5 0.3 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EMC81917.1 - 0.02 14.4 2.8 0.91 9.0 1.9 2.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 EMC81917.1 - 0.063 13.2 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Homeobox PF00046.24 EMC81918.1 - 4.4e-25 87.0 6.4 5.3e-25 86.7 4.4 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC81918.1 - 0.0002 20.9 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain Staygreen PF12638.2 EMC81918.1 - 0.012 15.1 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 Staygreen protein PRA-CH PF01502.13 EMC81918.1 - 0.1 12.2 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase HA PF03457.9 EMC81918.1 - 2.1 8.5 5.7 1.7 8.7 3.0 1.7 1 1 1 2 2 2 0 Helicase associated domain SNF PF00209.13 EMC81919.1 - 5.2e-221 734.6 32.8 6.5e-221 734.3 22.7 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ion_trans PF00520.26 EMC81920.1 - 1.1e-32 112.9 8.5 1.9e-32 112.1 5.9 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EMC81920.1 - 3e-10 39.6 4.1 3e-10 39.6 2.8 2.5 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC81920.1 - 6.4 5.0 9.6 0.44 8.8 2.4 1.9 1 1 1 2 2 2 0 Polycystin cation channel SPOC PF07744.8 EMC81921.1 - 1.4e-21 77.2 0.0 2.4e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.17 EMC81921.1 - 2.7e-19 68.5 0.0 1.9e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC81921.1 - 2.6e-17 62.5 0.0 4.6e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC81921.1 - 1.1e-10 41.2 0.0 3.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC81921.1 - 2.6e-07 30.2 0.0 0.00047 19.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMC81921.1 - 7e-05 22.6 0.0 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif K_channel_TID PF07941.6 EMC81921.1 - 4.5 7.5 9.4 0.17 12.1 1.1 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MFS_1 PF07690.11 EMC81922.1 - 5e-25 87.9 28.8 1.6e-13 50.1 1.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Prokineticin PF06607.6 EMC81924.1 - 4.7e-14 52.2 5.0 1.4e-11 44.3 1.5 2.0 1 1 1 2 2 2 2 Prokineticin Viral_cys_rich PF08008.7 EMC81924.1 - 0.05 13.1 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Viral cysteine rich PGPGW PF09656.5 EMC81924.1 - 1.6 8.1 5.0 2 7.7 3.4 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Ion_trans PF00520.26 EMC81925.1 - 2.4e-33 115.0 11.0 4.4e-33 114.2 6.5 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC81925.1 - 1.5e-27 95.6 0.0 3.2e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC81925.1 - 7.6e-13 47.9 6.0 7.6e-13 47.9 4.1 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 EMC81925.1 - 4.2e-05 22.1 0.7 4.2e-05 22.1 0.5 2.1 1 1 0 2 2 2 1 Polycystin cation channel DUF423 PF04241.10 EMC81925.1 - 0.22 11.4 1.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF202 PF02656.10 EMC81925.1 - 1.3 9.2 4.4 49 4.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Ion_trans PF00520.26 EMC81926.1 - 3.1e-35 121.2 5.1 3.1e-35 121.2 3.6 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC81926.1 - 5.8e-29 100.1 0.1 9.2e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC81926.1 - 2.4e-14 52.7 4.8 2.4e-14 52.7 3.3 2.5 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC81926.1 - 0.00079 17.9 0.8 0.00079 17.9 0.6 1.5 2 0 0 2 2 2 1 Polycystin cation channel DUF202 PF02656.10 EMC81926.1 - 3.9 7.7 5.7 89 3.4 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ion_trans PF00520.26 EMC81927.1 - 5.8e-34 117.1 8.1 1.2e-33 116.0 4.6 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EMC81927.1 - 1.3e-13 50.4 6.0 1.3e-13 50.4 4.2 2.5 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC81927.1 - 5.4e-05 21.7 0.6 9.9e-05 20.9 0.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Patatin PF01734.17 EMC81928.1 - 1.3e-08 35.0 1.3 1.2e-06 28.6 0.9 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Ets PF00178.17 EMC81930.1 - 4.6e-32 109.9 2.3 4.6e-32 109.9 1.6 1.8 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 EMC81930.1 - 2.1e-25 88.3 0.0 5.6e-25 86.9 0.0 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain FbpA PF05833.6 EMC81930.1 - 0.015 13.8 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HSF_DNA-bind PF00447.12 EMC81930.1 - 0.031 14.4 0.1 0.071 13.2 0.1 1.7 1 0 0 1 1 1 0 HSF-type DNA-binding BTB_2 PF02214.17 EMC81931.1 - 7e-06 26.1 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 EMC81932.1 - 6.8e-58 195.8 0.4 6.8e-58 195.8 0.3 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81932.1 - 4.6e-29 101.2 2.5 9.2e-26 90.4 1.7 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMC81932.1 - 1.2e-06 28.9 0.5 2.7e-06 27.7 0.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC81932.1 - 3e-06 26.4 0.4 3.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC81932.1 - 0.0019 17.2 0.6 0.0033 16.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC81932.1 - 0.003 17.3 0.1 0.028 14.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Alpha-2-MRAP_N PF06400.6 EMC81932.1 - 0.025 14.2 1.5 0.055 13.1 1.1 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain VRP3 PF03536.10 EMC81932.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein Seadorna_VP7 PF07387.6 EMC81932.1 - 0.074 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RRM_1 PF00076.17 EMC81933.1 - 7.3e-18 63.9 0.0 1.1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC81933.1 - 3.6e-11 42.8 0.0 5.2e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC81933.1 - 3.3e-10 39.6 0.0 4.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDI PF02234.14 EMC81934.1 - 8.7e-22 76.6 2.4 1.1e-21 76.3 1.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor DUF2481 PF10654.4 EMC81934.1 - 0.0035 17.0 0.0 0.0035 17.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2481) Ras PF00071.17 EMC81935.1 - 2.3e-49 166.8 0.0 2.7e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81935.1 - 2.3e-19 70.0 0.0 4.9e-19 68.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC81935.1 - 2.8e-15 55.9 0.0 3.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC81935.1 - 2.7e-06 26.7 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMC81935.1 - 9.2e-06 24.9 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC81935.1 - 1.2e-05 24.8 0.0 0.00044 19.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC81935.1 - 9.2e-05 22.3 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase CAP PF00188.21 EMC81937.1 - 2.9e-16 60.0 1.0 3.8e-16 59.6 0.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mito_carr PF00153.22 EMC81938.1 - 7.1e-16 57.7 0.2 4.3e-10 39.1 0.0 3.0 3 1 0 3 3 3 2 Mitochondrial carrier protein Pkinase PF00069.20 EMC81939.1 - 8.2e-47 159.5 0.0 1.6e-46 158.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81939.1 - 7.2e-13 48.1 0.0 1.2e-12 47.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC81939.1 - 4.5e-09 35.6 0.0 5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC81939.1 - 6.6e-06 25.3 0.0 9.5e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC81939.1 - 0.019 14.6 0.2 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC81939.1 - 0.046 13.2 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EMC81939.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EMC81939.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.13 EMC81940.1 - 7.3e-51 172.6 2.9 1e-50 172.2 2.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NGF PF00243.13 EMC81941.1 - 2e-52 175.8 0.6 2.7e-52 175.4 0.4 1.2 1 0 0 1 1 1 1 Nerve growth factor family Tetraspannin PF00335.15 EMC81942.1 - 4.1e-34 117.8 11.3 5.1e-34 117.4 7.9 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 EMC81942.1 - 0.18 11.7 7.2 0.38 10.6 5.0 1.7 1 1 0 1 1 1 0 CD20-like family Cys_knot PF00007.17 EMC81943.1 - 2.3e-31 107.9 15.5 2.8e-31 107.6 10.8 1.1 1 0 0 1 1 1 1 Cystine-knot domain zf-C4 PF00105.13 EMC81944.1 - 5.1e-29 100.3 14.4 5.1e-29 100.3 10.0 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC81944.1 - 1.3e-18 66.8 0.0 2.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF837 PF05769.6 EMC81945.1 - 9.9e-38 129.4 7.5 1.1e-37 129.3 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF837) Herpes_BLRF2 PF05812.7 EMC81945.1 - 0.01 15.6 0.8 0.017 14.9 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Stathmin PF00836.14 EMC81945.1 - 0.21 11.1 4.2 0.32 10.6 2.9 1.3 1 1 0 1 1 1 0 Stathmin family DUF972 PF06156.8 EMC81945.1 - 2 8.8 5.2 1 9.7 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ras PF00071.17 EMC81946.1 - 1e-42 145.3 0.1 1.1e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81946.1 - 2.6e-11 44.0 0.0 3.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC81946.1 - 2e-07 30.6 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMC81946.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EMC81946.1 - 0.0052 16.0 0.0 0.01 15.1 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B A_deaminase PF00962.17 EMC81947.1 - 2.8e-121 404.4 0.4 4.3e-121 403.8 0.3 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DENN PF02141.16 EMC81948.1 - 1.3e-60 204.3 1.4 2.2e-60 203.5 0.9 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EMC81948.1 - 8e-21 73.8 3.2 1.7e-20 72.8 2.3 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EMC81948.1 - 9.5e-21 73.5 1.3 1.9e-20 72.5 0.9 1.5 1 0 0 1 1 1 1 uDENN domain Bromodomain PF00439.20 EMC81949.1 - 9.7e-23 79.8 0.3 2.7e-22 78.4 0.2 1.8 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.19 EMC81949.1 - 8.2e-12 44.8 19.4 7.3e-09 35.3 5.1 4.7 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.24 EMC81949.1 - 1.7e-08 33.9 9.6 1.7e-08 33.9 6.7 4.0 3 0 0 3 3 3 1 PHD-finger SpoIISB_antitox PF14185.1 EMC81949.1 - 0.052 13.2 1.7 0.14 11.9 0.7 2.1 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system YgbB PF02542.11 EMC81949.1 - 0.18 11.6 2.4 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 YgbB family C2 PF00168.25 EMC81950.1 - 3.7e-56 186.9 0.1 2.6e-26 91.2 0.0 3.2 3 0 0 3 3 3 3 C2 domain CEP76-C2 PF15627.1 EMC81950.1 - 0.00016 21.2 0.1 0.019 14.4 0.0 2.9 3 0 0 3 3 3 1 CEP76 C2 domain T2SM PF04612.7 EMC81950.1 - 0.044 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M OLF PF02191.11 EMC81951.1 - 1.3e-83 280.1 0.0 1.6e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Sugarporin_N PF11471.3 EMC81951.1 - 0.023 14.3 1.1 0.075 12.6 0.7 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension IncA PF04156.9 EMC81951.1 - 0.48 10.0 3.2 0.74 9.3 2.2 1.3 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EMC81951.1 - 0.52 10.1 8.9 3 7.7 2.0 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Tropomyosin_1 PF12718.2 EMC81951.1 - 3.2 7.5 10.0 15 5.4 7.0 2.0 1 1 0 1 1 1 0 Tropomyosin like Pkinase PF00069.20 EMC81953.1 - 4.7e-53 179.9 0.0 7.6e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81953.1 - 2.8e-24 85.5 0.0 4.6e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC81953.1 - 2.4e-05 23.5 0.0 6.8e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC81953.1 - 0.005 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMC81953.1 - 0.01 14.6 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 EMC81953.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DRMBL PF07522.9 EMC81954.1 - 4.7e-16 58.7 0.0 9.9e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EMC81954.1 - 6.7e-11 42.0 0.2 2.1e-10 40.4 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC81954.1 - 0.0028 17.3 2.0 0.0045 16.6 0.5 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EMC81954.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Y_phosphatase PF00102.22 EMC81955.1 - 2.1e-81 272.7 0.1 2.5e-81 272.4 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC81955.1 - 0.00014 22.1 0.0 0.0004 20.6 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EMC81955.1 - 0.00085 18.9 0.1 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC81955.1 - 0.05 13.6 0.1 0.23 11.4 0.0 2.1 2 1 0 2 2 2 0 Inositol hexakisphosphate Phtf-FEM1B_bdg PF12129.3 EMC81957.1 - 8.6e-70 233.1 2.9 1.9e-69 232.0 2.0 1.6 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor MFS_1 PF07690.11 EMC81960.1 - 5.9e-25 87.7 21.7 6.7e-20 71.0 14.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC81960.1 - 0.015 15.0 5.1 0.061 13.1 2.6 2.7 2 1 1 3 3 3 0 MFS_1 like family DUF2140 PF09911.4 EMC81960.1 - 0.024 13.7 0.0 2 7.5 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) TAFA PF12020.3 EMC81961.1 - 9.1e-58 192.3 10.9 1.3e-57 191.8 7.6 1.2 1 0 0 1 1 1 1 TAFA family PP2C PF00481.16 EMC81962.1 - 1.2e-26 93.6 0.0 2.3e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EMC81962.1 - 5.5e-06 26.2 0.0 0.0046 16.6 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF424 PF04242.8 EMC81962.1 - 0.15 12.0 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Ras PF00071.17 EMC81963.1 - 3.9e-58 195.4 0.0 4.5e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC81963.1 - 1.4e-16 61.0 0.0 1.9e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC81963.1 - 2e-10 40.1 0.0 3.4e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC81963.1 - 3.3e-05 23.3 0.0 8.7e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC81963.1 - 0.014 14.5 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMC81963.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_12 PF13087.1 EMC81964.1 - 9e-49 165.5 0.0 1.3e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMC81964.1 - 7.8e-33 114.0 0.0 2.1e-15 56.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EMC81964.1 - 8.2e-10 38.3 0.0 1.6e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMC81964.1 - 3.1e-09 36.7 0.0 2.8e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EMC81964.1 - 0.00034 20.4 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.9 EMC81964.1 - 0.013 14.4 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.1 EMC81964.1 - 0.016 15.3 0.0 0.048 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMC81964.1 - 0.019 15.1 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EMC81964.1 - 0.035 14.2 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EMC81964.1 - 0.037 13.3 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EMC81964.1 - 0.05 13.0 0.2 9.9 5.5 0.0 2.8 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_24 PF13479.1 EMC81964.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC81964.1 - 0.16 11.5 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain HOOK PF05622.7 EMC81964.1 - 0.16 9.7 0.0 0.26 9.0 0.0 1.2 1 0 0 1 1 1 0 HOOK protein F-actin_cap_A PF01267.12 EMC81966.1 - 1e-102 342.8 0.5 1.2e-102 342.6 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ST7 PF04184.7 EMC81967.1 - 3.2e-302 1002.5 2.4 3.6e-302 1002.4 1.7 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.1 EMC81967.1 - 0.0006 20.0 0.5 0.0026 18.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC81967.1 - 0.024 14.5 4.4 1.5 8.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC81967.1 - 0.031 13.8 4.4 9.1 6.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.15 EMC81967.1 - 0.033 13.8 0.2 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_16 PF13432.1 EMC81967.1 - 0.15 12.7 5.5 0.92 10.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC81967.1 - 1.1 8.9 8.9 16 5.2 0.0 4.1 3 1 2 5 5 5 0 TPR repeat TPR_19 PF14559.1 EMC81967.1 - 1.2 9.5 7.3 0.66 10.3 0.1 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC81967.1 - 7.1 7.5 10.4 47 5.0 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat wnt PF00110.14 EMC81969.1 - 1.1e-93 313.8 6.9 1.2e-93 313.6 4.8 1.0 1 0 0 1 1 1 1 wnt family SUI1 PF01253.17 EMC81970.1 - 2.7e-15 55.9 0.4 4.9e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 EMC81970.1 - 0.00012 21.7 0.4 0.00038 20.1 0.1 1.9 2 0 0 2 2 2 1 PUA domain SWIB PF02201.13 EMC81970.1 - 0.0056 16.3 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.20 EMC81971.1 - 4.9e-61 206.1 0.0 7.5e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81971.1 - 1.1e-21 77.0 0.1 2.5e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC81971.1 - 4.2e-05 23.3 0.0 0.0027 17.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC81971.1 - 0.00036 19.9 2.6 0.021 14.1 0.0 2.5 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EMC81971.1 - 0.00074 19.1 0.2 0.0021 17.6 0.1 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMC81971.1 - 0.0037 16.6 1.9 0.0051 16.1 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EMC81971.1 - 0.036 13.1 0.2 0.064 12.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EMC81972.1 - 1.1e-58 198.4 0.0 1.4e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81972.1 - 6e-27 94.3 0.0 8.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC81972.1 - 2.6e-06 26.6 0.0 3.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC81972.1 - 1.4e-05 24.2 0.0 2.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMC81972.1 - 0.034 13.7 0.4 0.095 12.2 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase IL10 PF00726.12 EMC81973.1 - 2.2e-50 170.3 2.0 2.6e-50 170.0 1.4 1.0 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.1 EMC81973.1 - 2.5e-08 34.0 0.8 3.3e-08 33.6 0.6 1.1 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor TFIID-18kDa PF02269.11 EMC81973.1 - 0.015 15.1 0.2 0.032 14.0 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF2164 PF09932.4 EMC81973.1 - 0.1 12.4 1.8 0.63 9.8 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) IL10 PF00726.12 EMC81974.1 - 1.9e-06 27.3 0.1 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.1 EMC81974.1 - 6.1e-06 26.3 0.2 8.8e-06 25.8 0.2 1.1 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor V-set PF07686.12 EMC81975.1 - 2.7e-54 181.9 13.3 6.2e-15 55.0 0.3 5.4 4 1 1 5 5 5 5 Immunoglobulin V-set domain ig PF00047.20 EMC81975.1 - 1.9e-11 43.8 17.4 0.022 14.8 0.3 6.6 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.11 EMC81975.1 - 3.6e-11 42.7 3.0 0.58 10.0 0.2 6.1 5 2 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC81975.1 - 3.6e-10 39.8 11.9 0.0043 17.1 0.1 5.7 5 1 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 EMC81975.1 - 0.006 17.0 21.5 6 7.4 0.1 6.8 6 2 0 6 6 6 1 Immunoglobulin domain IL2 PF00715.12 EMC81975.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Interleukin 2 OTU PF02338.14 EMC81976.1 - 1.2e-11 45.2 0.0 2.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 EMC81976.1 - 0.028 14.5 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) E6 PF00518.12 EMC81976.1 - 0.093 13.0 0.4 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Early Protein (E6) zf-met PF12874.2 EMC81976.1 - 2 8.7 4.7 2.5 8.4 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type 6PF2K PF01591.13 EMC81977.1 - 4.5e-102 339.8 0.9 6.7e-102 339.2 0.6 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMC81977.1 - 1.3e-35 122.8 0.0 2e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMC81977.1 - 1.8e-09 37.6 0.0 3.3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMC81977.1 - 9.7e-06 24.9 0.1 1.9e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EMC81977.1 - 3.5e-05 24.5 0.3 0.00011 22.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC81977.1 - 0.036 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF421 PF04239.7 EMC81977.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF421) APS_kinase PF01583.15 EMC81977.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 EMC81977.1 - 0.1 12.8 0.0 2.1 8.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain His_Phos_2 PF00328.17 EMC81977.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Sushi PF00084.15 EMC81978.1 - 1e-50 169.8 33.6 2.5e-12 46.9 1.6 6.4 5 2 1 6 6 6 6 Sushi domain (SCR repeat) DUF281 PF03436.8 EMC81978.1 - 0.007 16.3 6.8 1.4 9.0 0.1 4.7 3 1 1 4 4 4 2 Domain of unknown function (DUF281) CD34_antigen PF06365.7 EMC81979.1 - 1.8e-20 73.4 0.0 2e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4064 PF13273.1 EMC81979.1 - 0.089 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Pkinase PF00069.20 EMC81980.1 - 1.4e-76 257.0 0.0 2e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC81980.1 - 3e-35 121.5 0.0 4.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC81980.1 - 5.9e-09 35.3 0.0 4.3e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EMC81980.1 - 0.0004 19.5 0.0 0.00069 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC81980.1 - 0.00061 19.6 0.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EMC81980.1 - 0.0009 18.6 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EMC81980.1 - 0.0091 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Streptin-Immun PF11083.3 EMC81981.1 - 0.0045 16.9 0.6 0.064 13.2 0.0 2.6 2 0 0 2 2 2 1 Lantibiotic streptin immunity protein Tropomyosin_1 PF12718.2 EMC81981.1 - 0.011 15.5 11.4 0.14 12.0 0.2 3.4 3 0 0 3 3 3 0 Tropomyosin like Acid_phosphat_B PF03767.9 EMC81981.1 - 0.032 13.6 0.1 0.079 12.3 0.1 1.6 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Erp_C PF06780.6 EMC81981.1 - 0.056 13.2 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Erp protein C-terminus DUF948 PF06103.6 EMC81981.1 - 0.079 12.8 6.7 0.18 11.6 0.1 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1843 PF08898.5 EMC81981.1 - 0.11 12.6 3.6 0.6 10.1 0.4 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF1843) TBPIP PF07106.8 EMC81981.1 - 0.13 11.7 6.6 1.3 8.5 0.2 2.8 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Paramyxo_C PF01692.13 EMC81981.1 - 0.26 10.8 4.3 2.6 7.6 0.0 2.6 3 0 0 3 3 3 0 Paramyxovirus non-structural protein c Laminin_II PF06009.7 EMC81981.1 - 0.73 9.5 12.9 1.5 8.5 0.5 3.5 3 1 0 3 3 3 0 Laminin Domain II Bacillus_HBL PF05791.6 EMC81981.1 - 1.7 7.9 8.2 4.2 6.7 0.7 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.7 EMC81981.1 - 2.3 8.5 7.6 14 5.9 0.0 4.4 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein ISG65-75 PF11727.3 EMC81981.1 - 2.8 6.9 8.0 0.52 9.3 0.1 2.7 2 1 1 3 3 3 0 Invariant surface glycoprotein COG2 PF06148.6 EMC81981.1 - 3.1 7.6 9.8 0.29 10.9 0.4 3.4 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoO PF09769.4 EMC81981.1 - 3.2 7.4 6.8 8.1 6.1 0.1 3.7 5 0 0 5 5 5 0 Apolipoprotein O TPR_MLP1_2 PF07926.7 EMC81981.1 - 7.7 6.2 14.6 0.99 9.1 0.5 3.5 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Laminin_EGF PF00053.19 EMC81982.1 - 8.6e-39 131.2 67.5 6e-12 45.3 7.5 4.1 4 0 0 4 4 4 4 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EMC81982.1 - 0.029 14.5 3.5 0.029 14.5 2.5 7.3 7 1 0 7 7 7 0 EGF-like domain adh_short PF00106.20 EMC81983.1 - 1.4e-27 96.6 0.8 1.8e-27 96.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC81983.1 - 4e-10 39.8 0.1 5.4e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC81983.1 - 4e-08 33.1 2.0 3e-07 30.2 1.4 1.9 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMC81983.1 - 0.00045 19.4 0.0 0.0026 16.9 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 EMC81983.1 - 0.00058 19.9 0.5 0.00092 19.3 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EMC81983.1 - 0.003 16.6 0.2 0.0091 15.0 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EMC81983.1 - 0.0067 16.4 0.1 0.013 15.4 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding FMO-like PF00743.14 EMC81983.1 - 0.0098 14.1 0.0 0.016 13.4 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NmrA PF05368.8 EMC81983.1 - 0.01 15.1 0.4 0.016 14.4 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.10 EMC81983.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Eno-Rase_NADH_b PF12242.3 EMC81983.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMC81983.1 - 0.018 14.4 0.1 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMC81983.1 - 0.07 12.7 0.5 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMC81983.1 - 0.087 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EMC81984.1 - 6.1e-25 88.0 0.0 7.5e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC81984.1 - 2.4e-08 33.8 1.1 1.9e-07 30.9 0.8 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC81984.1 - 5.3e-07 29.6 0.1 6.8e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMC81984.1 - 8.4e-07 28.4 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMC81984.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EMC81984.1 - 0.037 14.1 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EMC81984.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EMC81984.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EF-hand_7 PF13499.1 EMC81985.1 - 1.4e-30 105.2 5.5 9.3e-14 51.3 0.0 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EMC81985.1 - 1.1e-22 77.4 11.1 1.4e-06 27.1 0.1 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EMC81985.1 - 8.8e-19 65.6 6.6 0.0001 21.8 0.4 4.9 4 2 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 EMC81985.1 - 4e-17 61.5 1.6 1.3e-08 34.3 0.0 3.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC81985.1 - 4.1e-16 57.5 9.2 1.6e-05 24.0 0.1 4.4 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 EMC81985.1 - 5e-07 29.7 0.4 0.024 14.6 0.0 3.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC81985.1 - 0.012 15.3 1.9 2.8 7.7 0.1 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand AXE1 PF05448.7 EMC81985.1 - 0.044 12.2 0.0 0.058 11.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3408 PF11888.3 EMC81985.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EF-hand_7 PF13499.1 EMC81986.1 - 5.7e-26 90.4 13.1 6.2e-13 48.6 0.2 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EMC81986.1 - 4.7e-22 75.5 11.4 8.4e-07 27.8 0.2 4.9 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.1 EMC81986.1 - 1.9e-19 69.0 3.6 4.8e-09 35.6 0.4 2.7 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC81986.1 - 5.2e-19 66.3 6.1 6e-05 22.6 0.0 4.9 4 2 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EMC81986.1 - 2.1e-14 52.0 12.2 2.2e-05 23.5 0.5 4.9 5 1 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 EMC81986.1 - 4.7e-08 33.0 0.5 8e-05 22.6 0.0 2.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC81986.1 - 1.4e-05 24.7 2.8 0.25 11.0 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand VCBS PF13517.1 EMC81986.1 - 0.15 12.4 2.1 11 6.4 0.0 3.2 2 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WD40 PF00400.27 EMC81988.1 - 9.9e-14 50.6 15.4 0.00015 21.5 0.3 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_S24 PF00717.18 EMC81988.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like NinE PF05322.6 EMC81988.1 - 0.067 12.9 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 NINE Protein Mt_ATP-synt_B PF05405.9 EMC81989.1 - 1.9e-50 170.5 8.3 2.2e-50 170.3 5.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TraQ PF09679.5 EMC81989.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) 7tm_1 PF00001.16 EMC81990.1 - 2.4e-56 190.7 23.8 2.9e-56 190.4 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC81990.1 - 9.2e-13 47.9 24.3 1.1e-12 47.6 16.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0182 PF03699.8 EMC81990.1 - 4.6 5.0 9.4 5.7 4.7 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Se-cys_synth_N PF12390.3 EMC81991.1 - 2.1 8.5 16.9 5.8 7.0 0.1 5.4 5 0 0 5 5 5 0 Selenocysteine synthase N terminal Collagen PF01391.13 EMC81992.1 - 0.0017 17.8 7.0 0.012 15.1 3.5 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Myosin_head PF00063.16 EMC81993.1 - 0.0082 14.2 0.0 0.011 13.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) 7tm_2 PF00002.19 EMC81994.1 - 3e-65 219.6 17.3 4.1e-65 219.2 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TSP_1 PF00090.14 EMC81994.1 - 2.9e-48 161.7 82.7 2e-13 50.2 4.9 6.0 6 0 0 6 6 6 5 Thrombospondin type 1 domain DUF3497 PF12003.3 EMC81994.1 - 7.2e-36 123.5 0.2 1.8e-34 119.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3497) GPS PF01825.16 EMC81994.1 - 5.7e-12 45.5 0.6 5.7e-12 45.5 0.4 2.8 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain NDUF_B12 PF08122.7 EMC81994.1 - 0.028 14.1 0.2 0.08 12.6 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF3422 PF11902.3 EMC81994.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Retrotrans_gag PF03732.12 EMC81995.1 - 0.00067 19.6 2.2 0.0012 18.8 0.3 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Apolipoprotein PF01442.13 EMC81995.1 - 0.0052 16.3 2.0 0.012 15.0 0.5 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain HCR PF07111.7 EMC81995.1 - 0.033 12.1 0.3 0.046 11.7 0.2 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF842 PF05811.8 EMC81995.1 - 0.053 12.9 0.3 0.22 11.0 0.2 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF327 PF03885.8 EMC81995.1 - 0.068 12.9 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF327) SYCE1 PF15233.1 EMC81995.1 - 0.14 12.0 3.0 0.23 11.3 0.1 2.4 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 THRAP3_BCLAF1 PF15440.1 EMC81996.1 - 0.024 13.3 85.9 0.027 13.1 59.5 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Mab-21 PF03281.9 EMC81997.1 - 6.5e-15 55.0 0.7 1.7e-13 50.4 0.7 2.1 2 0 0 2 2 2 1 Mab-21 protein TFIIE-A_C-term PF11521.3 EMC81997.1 - 0.011 15.6 1.4 0.024 14.5 1.0 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha FERM_M PF00373.13 EMC81998.1 - 8.4e-48 161.7 1.1 1.4e-47 161.0 0.1 1.9 2 0 0 2 2 2 1 FERM central domain PH PF00169.24 EMC81998.1 - 8.1e-09 35.6 0.1 2.2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 PH domain FERM_N PF09379.5 EMC81998.1 - 3.5e-07 30.1 0.0 1.3e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 FERM N-terminal domain Tenui_NCP PF04876.7 EMC81998.1 - 0.025 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein TGFb_propeptide PF00688.13 EMC81999.1 - 4.5e-78 261.8 4.5 7.4e-78 261.1 3.1 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC81999.1 - 7e-41 138.7 0.8 1.2e-40 138.0 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain CDKN3 PF05706.7 EMC82000.1 - 3e-71 238.2 1.8 3.4e-71 238.0 1.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.15 EMC82000.1 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC82000.1 - 8.1e-05 22.0 0.0 9.1e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ANF_receptor PF01094.23 EMC82000.1 - 0.034 12.9 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Connexin PF00029.14 EMC82001.1 - 1.2e-51 173.2 0.3 2.9e-51 172.0 0.2 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC82001.1 - 4.6e-31 106.4 10.7 1.1e-30 105.1 7.4 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain GCV_T_C PF08669.6 EMC82003.1 - 2.4e-08 33.8 0.0 3.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.16 EMC82003.1 - 0.14 11.5 0.0 0.33 10.2 0.0 1.6 1 1 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF4582 PF15189.1 EMC82004.1 - 1.7e-79 264.9 1.7 2.1e-79 264.7 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4582) DUF1510 PF07423.6 EMC82005.1 - 0.15 11.4 13.2 0.19 11.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 EMC82005.1 - 0.38 9.1 29.5 0.44 8.9 20.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 EMC82005.1 - 0.46 9.8 41.8 0.63 9.3 29.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNA_polI_A34 PF08208.6 EMC82005.1 - 0.62 9.7 21.0 0.79 9.3 14.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Rtf2 PF04641.7 EMC82005.1 - 0.68 9.0 13.3 0.89 8.7 9.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 EMC82005.1 - 1.5 8.6 12.4 1.7 8.4 8.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EMC82005.1 - 1.5 8.6 10.7 1.8 8.2 7.4 1.2 1 0 0 1 1 1 0 DDHD domain DUF2413 PF10310.4 EMC82005.1 - 2.5 6.8 13.4 3.3 6.4 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Hid1 PF12722.2 EMC82005.1 - 2.8 5.5 4.5 3 5.4 3.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EMC82005.1 - 8.3 4.3 19.4 10 4.0 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.17 EMC82006.1 - 1.5e-45 155.6 0.1 4.7e-45 153.9 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 HIG_1_N PF04588.8 EMC82007.1 - 4.1e-23 80.8 0.8 6.8e-23 80.1 0.6 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF998 PF06197.8 EMC82007.1 - 0.0081 15.4 0.1 0.0096 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) LPP PF04728.8 EMC82008.1 - 0.019 14.7 5.7 0.44 10.3 0.1 4.3 5 0 0 5 5 5 0 Lipoprotein leucine-zipper MBOAT PF03062.14 EMC82009.1 - 1e-13 51.1 12.7 1e-13 51.1 8.8 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Kelch_1 PF01344.20 EMC82010.1 - 2.1e-36 123.2 0.0 2.1e-10 39.9 0.0 5.6 5 0 0 5 5 5 5 Kelch motif BTB PF00651.26 EMC82010.1 - 2.5e-35 120.8 1.9 5.2e-35 119.7 0.5 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.1 EMC82010.1 - 1.7e-30 103.9 0.0 2.5e-07 30.5 0.0 5.4 2 1 3 5 5 5 5 Kelch motif BACK PF07707.10 EMC82010.1 - 1.5e-28 98.6 0.7 7.9e-28 96.3 0.2 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 EMC82010.1 - 5.5e-21 74.0 0.0 8.9e-07 28.5 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC82010.1 - 8.2e-17 60.8 0.1 0.00016 21.7 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC82010.1 - 1.7e-14 53.3 0.3 0.0073 16.2 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EMC82010.1 - 4.3e-14 51.6 2.0 0.0085 15.8 0.0 5.5 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.3 EMC82010.1 - 0.0088 15.2 4.6 0.02 14.0 0.3 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) Pro_isomerase PF00160.16 EMC82012.1 - 8.8e-46 155.9 0.3 2.3e-45 154.5 0.2 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 EMC82012.1 - 5.5e-05 22.7 25.2 5.5e-05 22.7 17.4 9.8 4 3 5 9 9 9 1 Nuclear RNA-splicing-associated protein Longin PF13774.1 EMC82013.1 - 5e-15 54.8 0.0 8.6e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain 7tm_2 PF00002.19 EMC82014.1 - 1e-89 299.8 23.9 1.3e-89 299.5 16.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC82014.1 - 1.7e-22 79.2 3.4 3.3e-22 78.2 2.4 1.5 1 0 0 1 1 1 1 Hormone receptor domain DUF19 PF01579.13 EMC82014.1 - 0.039 13.9 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF19) MIP-T3 PF10243.4 EMC82015.1 - 1.3 7.3 94.2 1.7 7.0 65.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 EMC82015.1 - 1.8 6.1 29.5 1.7 6.2 20.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein 7tm_2 PF00002.19 EMC82016.1 - 2.8e-78 262.3 19.4 3.4e-78 262.0 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC82016.1 - 1.7e-20 72.7 1.8 1.7e-20 72.7 1.2 1.8 2 0 0 2 2 2 1 Hormone receptor domain TIP41 PF04176.8 EMC82016.1 - 0.051 12.8 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 TIP41-like family DUF843 PF05814.6 EMC82016.1 - 0.86 9.4 4.5 0.84 9.4 0.0 2.9 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) 7tm_2 PF00002.19 EMC82017.1 - 1.7e-89 299.0 15.8 4.4e-89 297.7 11.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC82017.1 - 3.4e-26 91.0 2.4 3.4e-26 91.0 1.6 2.5 2 0 0 2 2 2 1 Hormone receptor domain 7tm_2 PF00002.19 EMC82018.1 - 2.7e-77 259.1 19.5 3.3e-77 258.8 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC82018.1 - 1e-21 76.7 0.9 2.5e-21 75.4 0.7 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 EMC82018.1 - 4.6e-05 22.4 16.3 6.7e-05 21.9 11.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor MIP PF00230.15 EMC82019.1 - 3.2e-79 265.5 9.9 3.7e-79 265.3 6.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ank_2 PF12796.2 EMC82020.1 - 5.8e-48 161.1 3.5 1.4e-19 70.2 0.1 3.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC82020.1 - 1.1e-43 144.8 14.4 5.4e-08 32.2 0.0 7.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EMC82020.1 - 8.7e-37 124.8 3.3 4.9e-11 42.8 0.0 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC82020.1 - 1.1e-34 114.9 1.0 4.5e-06 26.3 0.0 8.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 EMC82020.1 - 1.1e-31 108.0 7.7 2.3e-08 34.0 0.1 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) SAM_1 PF00536.25 EMC82020.1 - 2.1e-09 37.4 0.2 5.8e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC82020.1 - 1.1e-07 31.5 0.1 2.8e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SOG2 PF10428.4 EMC82020.1 - 0.34 9.5 13.8 0.59 8.7 9.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CAP_N PF01213.14 EMC82020.1 - 2.4 7.3 8.4 0.73 9.0 2.5 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Glycos_transf_2 PF00535.21 EMC82021.1 - 9.9e-34 116.4 0.0 1.4e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMC82021.1 - 1.7e-10 41.0 0.0 2.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMC82021.1 - 4.4e-08 32.5 0.0 7.4e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC82021.1 - 2.9e-07 29.8 0.1 6.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase 7tm_3 PF00003.17 EMC82023.1 - 2.3e-43 148.2 12.9 3.1e-43 147.8 8.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 EMC82023.1 - 1e-30 106.7 0.1 1.7e-30 106.0 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EMC82023.1 - 3.6e-08 33.1 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF869 PF05911.6 EMC82023.1 - 0.02 13.1 1.7 0.03 12.5 1.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) PgaD PF13994.1 EMC82023.1 - 0.045 13.2 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 PgaD-like protein Cation_ATPase_C PF00689.16 EMC82023.1 - 5.1 6.5 14.2 1 8.8 2.7 3.0 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus WD40 PF00400.27 EMC82024.1 - 3e-63 207.5 35.3 1e-07 31.5 1.1 12.8 13 0 0 13 13 13 11 WD domain, G-beta repeat PD40 PF07676.7 EMC82024.1 - 0.045 13.4 1.5 1.3e+02 2.4 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Vinculin PF01044.14 EMC82025.1 - 3.6e-53 180.8 20.2 6.7e-33 113.8 3.6 3.5 3 1 0 3 3 3 3 Vinculin family COG5 PF10392.4 EMC82025.1 - 0.33 10.8 9.4 0.16 11.9 1.7 3.7 3 2 1 4 4 4 0 Golgi transport complex subunit 5 WXG100 PF06013.7 EMC82025.1 - 1.8 8.6 10.1 0.056 13.4 0.9 3.2 4 0 0 4 4 4 0 Proteins of 100 residues with WXG GCV_H PF01597.14 EMC82026.1 - 4.2e-08 32.9 0.1 8e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Glycine cleavage H-protein Zip PF02535.17 EMC82027.1 - 7.1e-101 337.3 14.6 7.1e-101 337.3 10.1 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter Patched PF02460.13 EMC82028.1 - 4.9e-90 302.6 18.3 6.9e-90 302.0 12.7 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EMC82028.1 - 3.7e-25 88.1 3.5 3.7e-25 88.1 2.4 3.0 4 0 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation SET PF00856.23 EMC82029.1 - 0.00013 22.3 0.1 0.00016 21.9 0.1 1.1 1 0 0 1 1 1 1 SET domain SEFIR PF08357.6 EMC82030.1 - 1e-55 187.8 0.3 2.1e-55 186.8 0.2 1.5 1 0 0 1 1 1 1 SEFIR domain fn3 PF00041.16 EMC82030.1 - 0.018 15.1 0.0 3.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Fibronectin type III domain DUF2141 PF09912.4 EMC82030.1 - 0.029 14.0 0.0 0.098 12.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF1863 PF08937.6 EMC82030.1 - 0.04 13.9 0.1 0.1 12.6 0.1 1.7 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) TIR_2 PF13676.1 EMC82030.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 TIR domain Homeobox PF00046.24 EMC82031.1 - 1.3e-23 82.3 2.3 1.8e-23 81.8 0.7 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EMC82031.1 - 0.0049 16.5 0.2 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Dynein_heavy PF03028.10 EMC82032.1 - 1.1e-246 820.3 0.0 2.7e-246 819.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EMC82032.1 - 7.8e-127 423.1 17.1 2.7e-126 421.4 11.8 2.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EMC82032.1 - 3.6e-94 314.6 0.9 1.3e-93 312.7 0.2 2.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EMC82032.1 - 9.6e-70 234.5 0.1 7.4e-69 231.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EMC82032.1 - 3e-60 202.9 0.7 2.5e-59 199.8 0.4 2.6 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 EMC82032.1 - 3.1e-54 183.9 0.1 7.3e-54 182.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 EMC82032.1 - 2.8e-48 164.4 13.6 2.8e-48 164.4 9.4 1.7 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EMC82032.1 - 1.7e-18 66.7 0.0 5.3e-07 29.4 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC82032.1 - 1.5e-08 34.8 1.2 0.14 12.0 0.0 5.7 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.24 EMC82032.1 - 1.9e-08 34.5 3.2 0.026 14.7 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC82032.1 - 6e-07 30.3 0.1 0.02 15.7 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 EMC82032.1 - 4.7e-05 23.5 0.2 6.5 6.9 0.0 5.2 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EMC82032.1 - 0.0001 22.4 0.2 6.2 7.0 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.1 EMC82032.1 - 0.00035 20.8 0.3 4 7.7 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.1 EMC82032.1 - 0.0007 19.3 0.1 1.3 8.8 0.1 3.7 4 0 0 4 4 3 1 Part of AAA domain ABC_tran PF00005.22 EMC82032.1 - 0.0062 16.8 0.1 8.8 6.6 0.0 3.7 3 0 0 3 3 2 0 ABC transporter NAAA-beta PF15508.1 EMC82032.1 - 0.0081 16.4 0.4 1.4 9.2 0.1 5.0 4 0 0 4 4 3 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAA_30 PF13604.1 EMC82032.1 - 0.0087 15.6 0.2 4.4 6.8 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EMC82032.1 - 0.02 14.3 0.1 2.6 7.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EMC82032.1 - 0.064 13.1 0.0 44 3.9 0.0 4.0 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.1 EMC82032.1 - 0.13 11.8 6.0 4.6 6.8 0.0 3.4 4 0 0 4 4 4 0 P-loop containing region of AAA domain Arf PF00025.16 EMC82033.1 - 5.9e-73 243.8 0.2 6.5e-73 243.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC82033.1 - 1.3e-14 53.8 0.0 1.6e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMC82033.1 - 1.6e-14 53.5 0.0 1.7e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC82033.1 - 3.7e-11 42.5 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC82033.1 - 7.5e-11 41.3 0.6 1e-09 37.6 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 EMC82033.1 - 2e-08 34.7 0.0 2.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC82033.1 - 5.6e-06 26.3 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMC82033.1 - 0.017 14.1 0.1 0.026 13.6 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EMC82033.1 - 0.021 14.2 0.2 0.079 12.3 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EMC82033.1 - 0.14 12.0 0.2 0.29 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain SPA PF08616.5 EMC82034.1 - 4e-16 58.7 0.2 2.7e-14 52.8 0.0 2.5 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 EMC82034.1 - 2.4e-07 30.6 3.3 2.4e-07 30.6 2.3 2.2 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 EMC82034.1 - 0.0021 16.6 0.0 0.004 15.6 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.1 EMC82034.1 - 0.14 12.4 0.2 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein FHA PF00498.21 EMC82035.1 - 1.7e-16 60.0 0.0 4.5e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain MscS_porin PF12795.2 EMC82035.1 - 0.00039 19.8 21.7 0.00039 19.8 15.0 5.6 2 2 3 5 5 5 3 Mechanosensitive ion channel porin domain Prefoldin_2 PF01920.15 EMC82035.1 - 0.0028 17.4 10.9 0.0028 17.4 7.5 9.8 3 3 5 9 9 9 3 Prefoldin subunit CENP-F_leu_zip PF10473.4 EMC82035.1 - 0.0072 16.1 23.1 0.0072 16.1 16.0 7.0 2 2 5 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.5 EMC82035.1 - 0.01 15.8 0.5 0.01 15.8 0.4 6.8 3 1 3 6 6 6 0 Bacterial type III secretion protein (HrpB7) HALZ PF02183.13 EMC82035.1 - 0.019 14.6 1.9 0.019 14.6 1.3 9.6 9 3 1 10 10 10 0 Homeobox associated leucine zipper Filamin PF00630.14 EMC82036.1 - 0 1266.9 52.6 4e-20 72.2 0.0 24.1 24 0 0 24 24 24 24 Filamin/ABP280 repeat Big_1 PF02369.11 EMC82036.1 - 3.8e-20 71.6 1.5 0.21 11.5 0.0 13.4 15 0 0 15 15 15 4 Bacterial Ig-like domain (group 1) CH PF00307.26 EMC82036.1 - 9.2e-18 64.2 0.0 1.9e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Y_Y_Y PF07495.8 EMC82036.1 - 2.3e-15 56.0 24.6 0.51 10.1 0.0 14.4 16 0 0 16 16 16 4 Y_Y_Y domain Big_3_4 PF13754.1 EMC82036.1 - 1e-07 32.1 41.2 0.38 11.1 0.1 15.0 17 1 1 18 18 18 2 Bacterial Ig-like domain (group 3) YtkA PF13115.1 EMC82036.1 - 0.00012 22.3 15.8 4.1 7.8 0.1 11.0 14 0 0 14 14 14 1 YtkA-like EMP24_GP25L PF01105.19 EMC82036.1 - 0.00027 20.6 1.0 47 3.6 0.0 7.7 9 1 1 10 10 10 0 emp24/gp25L/p24 family/GOLD PapC_N PF13954.1 EMC82036.1 - 0.00045 19.8 0.0 2.3 7.7 0.0 5.7 6 0 0 6 6 6 1 PapC N-terminal domain BatD PF13584.1 EMC82036.1 - 0.0012 17.4 3.7 0.44 9.0 0.0 4.2 5 0 0 5 5 5 2 Oxygen tolerance DUF2141 PF09912.4 EMC82036.1 - 0.006 16.2 6.6 20 4.9 0.0 7.4 9 1 1 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2141) Exo_endo_phos PF03372.18 EMC82037.1 - 8.6e-17 61.8 0.0 1e-16 61.6 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMC82037.1 - 3.7e-06 26.5 0.0 5.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Peptidase_M16 PF00675.15 EMC82038.1 - 2.2e-52 176.7 0.1 3.5e-52 176.1 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMC82038.1 - 5.5e-39 133.7 0.0 4.4e-38 130.8 0.0 2.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain PvlArgDC PF01862.11 EMC82038.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Kunitz_BPTI PF00014.18 EMC82039.1 - 7.2e-22 77.3 5.7 7.8e-22 77.2 3.9 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Adaptin_N PF01602.15 EMC82040.1 - 4.2e-127 424.6 11.6 5.3e-127 424.3 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EMC82040.1 - 1.1e-58 197.4 0.5 2.8e-58 196.0 0.3 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EMC82040.1 - 2.8e-15 56.3 1.3 0.0042 17.3 0.1 6.4 2 2 5 7 7 7 6 HEAT repeats HEAT PF02985.17 EMC82040.1 - 1.5e-07 30.8 5.5 3.5 7.9 0.0 7.2 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EMC82040.1 - 4.3e-06 27.0 2.3 0.011 16.1 0.0 3.6 3 1 1 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.11 EMC82040.1 - 0.055 13.9 1.3 24 5.7 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat ISG65-75 PF11727.3 EMC82040.1 - 0.15 11.0 0.5 13 4.7 0.0 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF159 PF02586.9 EMC82041.1 - 3.4e-44 150.8 0.1 7.6e-44 149.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 Histone PF00125.19 EMC82042.1 - 1.7e-26 92.0 0.0 2.2e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC82042.1 - 6.7e-05 22.8 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Linker_histone PF00538.14 EMC82043.1 - 2.1e-14 53.3 0.3 2.1e-14 53.3 0.2 1.7 1 1 1 2 2 2 1 linker histone H1 and H5 family DUF2572 PF10833.3 EMC82043.1 - 0.0038 16.6 0.3 0.005 16.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2572) EGF_CA PF07645.10 EMC82044.1 - 1.6e-14 53.5 31.8 3.2e-11 43.0 7.7 7.2 4 2 3 7 7 7 2 Calcium-binding EGF domain DUF3456 PF11938.3 EMC82044.1 - 4.8e-11 42.8 6.1 1.9e-06 27.9 2.0 3.2 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP VSP PF03302.8 EMC82044.1 - 0.00017 20.3 61.6 0.025 13.2 16.1 3.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein cEGF PF12662.2 EMC82044.1 - 0.00087 18.8 10.1 0.0018 17.8 1.2 6.2 6 1 0 6 6 6 2 Complement Clr-like EGF-like EGF PF00008.22 EMC82044.1 - 0.0037 17.1 1.0 0.0037 17.1 0.7 6.3 6 2 1 8 8 8 3 EGF-like domain EGF_3 PF12947.2 EMC82044.1 - 0.013 15.4 4.4 0.013 15.4 3.1 5.8 5 2 1 6 6 6 0 EGF domain EGF_MSP1_1 PF12946.2 EMC82044.1 - 0.021 14.6 4.6 0.021 14.6 3.2 5.0 4 1 1 5 5 5 0 MSP1 EGF domain 1 PmrD PF11183.3 EMC82044.1 - 0.028 14.2 0.3 0.07 12.9 0.2 1.7 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD hEGF PF12661.2 EMC82044.1 - 2.8 8.2 19.5 0.41 10.8 0.9 5.9 6 1 0 6 6 6 0 Human growth factor-like EGF IL17_R_N PF15037.1 EMC82046.1 - 2.3e-55 188.2 8.8 3.7e-55 187.5 6.1 1.4 1 1 0 1 1 1 1 Interleukin-17 receptor extracellular region Innexin PF00876.13 EMC82048.1 - 7.9e-08 31.7 5.6 8e-08 31.7 1.1 2.3 1 1 1 2 2 2 1 Innexin Tetraspannin PF00335.15 EMC82049.1 - 0.00079 18.7 4.7 0.00083 18.6 3.3 1.0 1 0 0 1 1 1 1 Tetraspanin family TMEM238 PF15125.1 EMC82049.1 - 0.0091 15.8 2.5 0.01 15.7 1.7 1.1 1 0 0 1 1 1 1 TMEM238 protein family DUF975 PF06161.6 EMC82049.1 - 0.69 9.5 5.1 0.66 9.6 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF975) TraB PF01963.12 EMC82050.1 - 4.1e-46 157.5 0.0 5.7e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 TraB family RRM_3 PF08777.6 EMC82050.1 - 0.036 13.9 0.1 0.54 10.1 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Glyco_tran_WecB PF03808.8 EMC82050.1 - 0.11 11.9 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Spc97_Spc98 PF04130.8 EMC82051.1 - 2.3e-10 39.4 0.6 4.3e-10 38.5 0.1 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family Hist_deacetyl PF00850.14 EMC82052.1 - 3.4e-55 187.5 0.3 4.1e-55 187.2 0.2 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF3313 PF11769.3 EMC82053.1 - 0.00018 20.9 6.0 23 4.2 0.0 6.2 3 1 5 8 8 8 6 Protein of unknown function (DUF3313) Gly_rich_SFCGS PF14272.1 EMC82053.1 - 0.0013 18.6 5.2 19 5.1 0.0 5.5 3 1 3 6 6 6 4 Glycine-rich SFCGS Fz PF01392.17 EMC82054.1 - 5.1e-29 100.9 6.9 5.1e-29 100.9 4.8 2.0 3 0 0 3 3 3 1 Fz domain NTR PF01759.16 EMC82054.1 - 0.02 14.4 0.2 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Pkinase PF00069.20 EMC82055.1 - 3.1e-67 226.4 0.1 4.4e-67 225.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82055.1 - 1.7e-27 96.1 0.1 2.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMC82055.1 - 0.00014 21.2 0.0 0.0003 20.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMC82055.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC82055.1 - 0.00082 18.4 0.0 0.0014 17.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC82055.1 - 0.0014 17.7 0.0 0.003 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Bcl-2 PF00452.14 EMC82056.1 - 0.00098 19.2 0.1 0.0041 17.2 0.0 2.1 1 1 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BID PF06393.6 EMC82056.1 - 0.1 11.9 0.0 0.6 9.4 0.0 2.0 2 0 0 2 2 2 0 BH3 interacting domain (BID) Ldl_recept_b PF00058.12 EMC82057.1 - 2.5e-158 514.1 48.4 1.1e-13 51.2 0.2 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 EMC82057.1 - 5.5e-39 131.9 68.3 3.7e-11 42.9 5.8 5.8 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.13 EMC82057.1 - 4.2e-32 109.7 48.1 1e-11 44.4 6.2 3.7 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A SGL PF08450.7 EMC82057.1 - 4.5e-17 62.2 15.9 0.096 12.0 0.0 11.8 7 3 3 12 12 12 5 SMP-30/Gluconolaconase/LRE-like region EGF PF00008.22 EMC82057.1 - 1.4e-05 24.9 55.2 0.011 15.6 2.3 6.3 5 1 0 5 5 5 4 EGF-like domain NHL PF01436.16 EMC82057.1 - 2.2e-05 24.1 0.0 4.8 7.3 0.0 6.4 6 0 0 6 6 6 1 NHL repeat cEGF PF12662.2 EMC82057.1 - 0.019 14.6 0.3 0.019 14.6 0.2 5.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like Plasmid_Txe PF06769.8 EMC82057.1 - 0.19 11.5 2.7 34 4.3 0.1 4.2 4 0 0 4 4 4 0 Plasmid encoded toxin Txe MANEC PF07502.9 EMC82058.1 - 9.2e-23 80.0 1.4 1.7e-22 79.2 1.0 1.4 1 0 0 1 1 1 1 MANEC domain LOH1CR12 PF10158.4 EMC82059.1 - 8.9e-57 190.5 1.3 1e-56 190.3 0.9 1.0 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.7 EMC82059.1 - 0.0068 16.2 0.8 0.0084 15.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ING PF12998.2 EMC82059.1 - 0.0076 16.5 2.1 0.01 16.1 1.2 1.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding BLOC1_2 PF10046.4 EMC82059.1 - 0.012 15.7 0.8 0.023 14.7 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.14 EMC82059.1 - 0.025 14.1 1.8 0.026 14.0 1.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MRL1 PF13003.2 EMC82059.1 - 0.027 14.2 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L1 DUF3445 PF11927.3 EMC82059.1 - 0.071 12.4 0.5 0.079 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) DUF3810 PF12725.2 EMC82059.1 - 0.11 11.3 1.3 0.14 11.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FH2 PF02181.18 EMC82059.1 - 0.28 10.0 3.3 0.29 9.9 1.5 1.5 1 1 1 2 2 2 0 Formin Homology 2 Domain DSPc PF00782.15 EMC82060.1 - 2e-42 143.9 0.0 3.7e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EMC82060.1 - 1.4e-12 47.9 0.0 1.2e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 EMC82060.1 - 1.9e-05 24.1 0.0 4.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC82060.1 - 0.056 13.4 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate bZIP_2 PF07716.10 EMC82061.1 - 5e-08 32.6 7.3 7.8e-08 32.0 5.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC82061.1 - 3.3e-07 30.1 5.9 5.4e-07 29.4 4.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor 7tm_1 PF00001.16 EMC82062.1 - 1.6e-46 158.5 18.2 2.1e-46 158.1 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82062.1 - 4.2e-08 32.6 20.7 5.9e-08 32.1 14.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CDI PF02234.14 EMC82063.1 - 2.8e-16 59.0 0.9 3e-16 58.9 0.6 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor CDI PF02234.14 EMC82064.1 - 6.6e-22 77.0 6.4 7.6e-22 76.8 2.1 2.3 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor Ion_trans PF00520.26 EMC82066.1 - 8e-25 87.2 7.1 8e-25 87.2 4.9 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EMC82066.1 - 1e-11 44.3 7.0 1e-11 44.3 4.8 2.6 3 1 1 4 4 4 1 Ion channel Dispanin PF04505.7 EMC82066.1 - 0.075 12.5 1.5 0.17 11.4 0.0 2.4 2 1 0 2 2 2 0 Interferon-induced transmembrane protein MRP-S28 PF10213.4 EMC82067.1 - 3.1e-33 114.5 0.2 6e-33 113.6 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein MANEC PF07502.9 EMC82068.1 - 8.3e-08 32.1 2.8 8.3e-08 32.1 1.9 1.8 2 0 0 2 2 2 1 MANEC domain Macoilin PF09726.4 EMC82068.1 - 7.6 4.6 13.2 10 4.2 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Kelch_1 PF01344.20 EMC82069.1 - 1e-31 108.1 7.4 1.2e-09 37.4 0.0 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EMC82069.1 - 1.2e-26 91.7 5.7 1e-08 34.9 0.0 5.8 4 2 1 5 5 5 5 Kelch motif Kelch_2 PF07646.10 EMC82069.1 - 2e-11 43.1 0.7 0.0073 16.0 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EMC82069.1 - 5.7e-11 42.1 0.3 0.00011 22.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EMC82069.1 - 3.2e-10 39.9 0.6 0.091 12.9 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC82069.1 - 2.8e-08 33.3 3.3 0.077 12.7 0.0 5.2 6 0 0 6 6 6 3 Galactose oxidase, central domain BTB PF00651.26 EMC82069.1 - 5.9e-05 23.0 0.0 0.0011 18.9 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EMC82069.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Parathyroid PF01279.12 EMC82070.1 - 1.7e-37 128.0 0.6 1.7e-37 128.0 0.4 1.5 2 0 0 2 2 2 1 Parathyroid hormone family Herpes_DNAp_acc PF04929.7 EMC82070.1 - 0.39 9.6 4.5 0.46 9.3 3.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-H2C2_2 PF13465.1 EMC82072.1 - 8.9e-33 110.9 33.4 1.6e-09 37.5 0.4 5.2 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC82072.1 - 2.1e-25 87.4 34.6 5.1e-07 29.6 0.3 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC82072.1 - 2.3e-13 49.5 26.8 0.00073 19.3 0.2 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC82072.1 - 2.6e-13 49.6 12.3 0.0061 16.6 0.0 4.6 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMC82072.1 - 1.1e-12 47.3 27.3 0.0035 17.5 0.2 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EMC82072.1 - 3.2e-06 27.1 20.3 0.13 12.5 0.6 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type Prok-RING_1 PF14446.1 EMC82072.1 - 0.0011 18.6 15.0 8.4 6.2 0.0 5.1 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 XPA_N PF01286.13 EMC82072.1 - 0.0048 16.5 19.0 1.1 8.9 0.0 5.0 5 0 0 5 5 5 1 XPA protein N-terminal TFIIS_C PF01096.13 EMC82072.1 - 0.0073 15.9 24.3 1.4 8.5 0.2 5.2 4 1 1 5 5 5 2 Transcription factor S-II (TFIIS) zf-BED PF02892.10 EMC82072.1 - 0.0094 15.6 27.8 0.23 11.2 1.8 4.9 1 1 4 5 5 5 3 BED zinc finger DNA_RNApol_7kD PF03604.8 EMC82072.1 - 0.02 14.3 18.3 0.92 9.0 0.5 4.9 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 EMC82072.1 - 0.041 13.8 29.0 1.9 8.4 0.2 4.9 3 2 0 3 3 3 0 Zinc ribbon domain C1_4 PF07975.7 EMC82072.1 - 0.053 13.5 25.3 0.55 10.2 2.6 4.5 1 1 4 5 5 5 0 TFIIH C1-like domain AMPKBI PF04739.10 EMC82072.1 - 0.077 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain LIM PF00412.17 EMC82072.1 - 0.13 12.3 21.2 0.13 12.3 1.1 3.7 2 1 1 3 3 3 0 LIM domain zf-trcl PF13451.1 EMC82072.1 - 0.18 11.4 21.3 13 5.5 4.4 4.5 4 1 0 4 4 4 0 Probable zinc-binding domain Zn_Tnp_IS1595 PF12760.2 EMC82072.1 - 0.22 11.3 24.1 0.47 10.2 3.5 4.7 4 1 0 4 4 4 0 Transposase zinc-ribbon domain zf-LYAR PF08790.6 EMC82072.1 - 0.24 11.1 15.9 1.1 8.9 0.0 4.9 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger BolA PF01722.13 EMC82072.1 - 1.1 9.3 4.0 15 5.6 0.1 2.3 2 0 0 2 2 2 0 BolA-like protein DZR PF12773.2 EMC82072.1 - 1.3 8.9 20.7 1.5e+04 -6.6 14.4 3.6 1 1 0 1 1 0 0 Double zinc ribbon COX5B PF01215.14 EMC82072.1 - 1.5 8.4 18.4 2.3 7.9 1.3 4.1 1 1 4 5 5 5 0 Cytochrome c oxidase subunit Vb CpXC PF14353.1 EMC82072.1 - 1.7 8.6 17.5 6.7 6.6 0.0 4.8 2 1 0 4 4 4 0 CpXC protein zf-RING_3 PF14369.1 EMC82072.1 - 2.1 8.4 13.6 11 6.0 0.0 4.9 5 0 0 5 5 5 0 zinc-finger Evr1_Alr PF04777.8 EMC82072.1 - 2.3 8.1 20.8 6.8 6.6 1.0 4.7 1 1 3 4 4 4 0 Erv1 / Alr family Fer4_10 PF13237.1 EMC82072.1 - 2.4 8.0 16.3 40 4.1 0.0 4.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain HNH PF01844.18 EMC82072.1 - 3.5 7.5 18.4 0.87 9.5 0.4 4.9 5 0 0 5 5 5 0 HNH endonuclease HypA PF01155.14 EMC82072.1 - 4.1 7.1 19.0 1.5e+04 -6.2 13.2 3.5 1 1 0 1 1 0 0 Hydrogenase expression/synthesis hypA family Yippee-Mis18 PF03226.9 EMC82072.1 - 8.2 6.5 17.7 22 5.1 5.5 4.0 2 2 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L37ae PF01780.14 EMC82072.1 - 8.7 6.2 15.3 23 4.9 3.3 3.9 1 1 2 3 3 3 0 Ribosomal L37ae protein family Baculo_PEP_C PF04513.7 EMC82073.1 - 0.037 13.8 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HCV_core PF01542.13 EMC82073.1 - 0.11 12.8 4.7 5.3 7.4 0.2 3.1 2 2 1 3 3 3 0 Hepatitis C virus core protein DASH_Dad3 PF08656.5 EMC82073.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad3 DUF1269 PF06897.7 EMC82073.1 - 0.18 11.8 3.1 0.9 9.6 1.3 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1269) RhoGEF PF00621.15 EMC82074.1 - 1.3e-37 129.3 3.2 1.3e-37 129.3 2.2 1.7 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.23 EMC82074.1 - 5.1e-11 41.7 0.1 1.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC82074.1 - 8.3e-11 41.2 0.0 1.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC82074.1 - 2.5e-08 33.2 0.0 4.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Homeobox PF00046.24 EMC82075.1 - 5.2e-23 80.4 2.2 1.4e-22 79.0 1.2 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EMC82075.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Tetraspannin PF00335.15 EMC82076.1 - 1.5e-41 142.1 12.1 1.7e-41 141.9 8.4 1.0 1 0 0 1 1 1 1 Tetraspanin family IncA PF04156.9 EMC82076.1 - 0.055 13.0 1.1 0.055 13.0 0.8 2.7 3 0 0 3 3 3 0 IncA protein PrgI PF12666.2 EMC82076.1 - 0.16 12.1 4.9 0.11 12.6 0.5 2.3 2 0 0 2 2 2 0 PrgI family protein Claudin_2 PF13903.1 EMC82076.1 - 0.92 9.1 9.4 0.17 11.5 2.7 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Cytochrom_B561 PF03188.11 EMC82076.1 - 1.2 8.9 9.7 0.13 12.1 3.0 1.9 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Tic20 PF09685.5 EMC82076.1 - 1.5 8.8 9.9 1.8 8.5 3.3 2.1 2 0 0 2 2 2 0 Tic20-like protein Oxidored_q3 PF00499.15 EMC82076.1 - 2 8.1 10.6 5.1 6.8 6.9 2.0 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 IBV_3C PF03620.8 EMC82076.1 - 4.1 7.3 6.3 10 6.1 3.2 2.6 1 1 1 2 2 2 0 IBV 3C protein DUF2207 PF09972.4 EMC82076.1 - 4.1 5.8 5.5 0.36 9.3 0.3 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) C8 PF08742.6 EMC82077.1 - 9.7e-20 70.6 5.4 9.7e-20 70.6 3.7 2.0 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 EMC82077.1 - 9.3e-08 32.0 11.8 9.3e-08 32.0 8.2 2.8 1 1 2 3 3 3 1 Trypsin Inhibitor like cysteine rich domain VWA PF00092.23 EMC82078.1 - 4.3e-35 121.0 0.2 1.5e-34 119.2 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWD PF00094.20 EMC82078.1 - 3.6e-26 92.2 0.7 8.8e-26 90.9 0.5 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.13 EMC82078.1 - 6.2e-08 32.6 43.5 5.2e-06 26.4 9.7 12.1 7 2 4 11 11 11 3 von Willebrand factor type C domain VWA_2 PF13519.1 EMC82078.1 - 2.9e-07 30.7 0.0 4.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Anoctamin PF04547.7 EMC82079.1 - 1.1e-145 485.7 12.2 1.4e-145 485.4 8.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2207 PF09972.4 EMC82079.1 - 0.00066 18.3 0.1 0.032 12.8 0.1 2.4 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) NGF PF00243.13 EMC82080.1 - 1e-60 202.5 4.8 1.6e-60 201.9 3.3 1.3 1 0 0 1 1 1 1 Nerve growth factor family ELO PF01151.13 EMC82081.1 - 3.1e-64 216.6 25.9 3.7e-64 216.4 17.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family YWFCY PF14293.1 EMC82081.1 - 8.7 6.2 10.1 1.6 8.5 0.3 3.4 3 0 0 3 3 3 0 YWFCY protein Ion_trans PF00520.26 EMC82082.1 - 2.8e-35 121.3 5.8 2.8e-35 121.3 4.0 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC82082.1 - 5.8e-29 100.1 0.6 1.1e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC82082.1 - 1.1e-13 50.7 5.3 1.1e-13 50.7 3.7 2.7 2 1 2 4 4 4 1 Ion channel PKD_channel PF08016.7 EMC82082.1 - 0.00075 18.0 1.0 0.0016 16.9 0.7 1.5 1 0 0 1 1 1 1 Polycystin cation channel Methyltransf_18 PF12847.2 EMC82084.1 - 2e-08 34.7 0.0 3.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC82084.1 - 3.4e-07 29.9 0.0 5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC82084.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC82084.1 - 0.00018 20.9 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMC82084.1 - 0.00024 20.3 0.3 0.0004 19.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EMC82084.1 - 0.00025 21.4 0.2 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC82084.1 - 0.00055 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC82084.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMC82084.1 - 0.058 12.4 0.1 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EMC82084.1 - 0.062 12.8 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GTP_EFTU PF00009.22 EMC82085.1 - 3.5e-27 95.0 0.0 5.4e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC82085.1 - 3.7e-18 65.5 0.7 8.9e-18 64.2 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC82085.1 - 3e-07 30.4 0.3 1.8e-06 27.9 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EMC82085.1 - 0.00023 20.6 0.0 1 8.8 0.0 3.6 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EMC82085.1 - 0.0017 18.2 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC82085.1 - 0.0042 17.5 0.1 0.045 14.2 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EMC82085.1 - 0.082 12.7 0.3 0.65 9.7 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Arf PF00025.16 EMC82085.1 - 0.14 11.3 0.1 12 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Sad1_UNC PF07738.8 EMC82086.1 - 7.6e-45 152.0 0.0 1.2e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spc7 PF08317.6 EMC82086.1 - 0.007 15.0 1.9 0.013 14.2 1.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Leu_zip PF15294.1 EMC82086.1 - 0.012 14.7 4.6 0.023 13.7 3.2 1.4 1 0 0 1 1 1 0 Leucine zipper Filament PF00038.16 EMC82086.1 - 0.07 12.5 7.5 0.019 14.4 2.2 2.0 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.10 EMC82086.1 - 2.3 7.7 8.5 12 5.4 0.1 4.0 3 1 1 4 4 4 0 Septum formation initiator HALZ PF02183.13 EMC82086.1 - 3 7.6 12.2 8.3 6.2 0.0 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF4618 PF15397.1 EMC82086.1 - 3.5 6.9 4.8 1.5 8.1 1.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) OmpH PF03938.9 EMC82086.1 - 4.1 7.3 10.0 19 5.1 7.0 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.1 EMC82086.1 - 7.3 6.6 8.5 17 5.4 0.1 3.5 3 1 0 4 4 4 0 FlxA-like protein DUF1193 PF06702.7 EMC82087.1 - 9.4e-106 352.1 0.0 1.2e-105 351.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 EMC82087.1 - 0.034 12.8 0.0 0.059 12.0 0.0 1.4 1 0 0 1 1 1 0 FAM198 protein Dynein_light PF01221.13 EMC82088.1 - 1.1e-28 99.0 0.3 1.2e-28 98.8 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.3 EMC82088.1 - 0.029 13.8 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) GARS_A PF01071.14 EMC82088.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pentaxin PF00354.12 EMC82089.1 - 2.7e-10 40.0 0.0 3.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 EMC82089.1 - 0.00032 20.9 0.0 0.00041 20.6 0.0 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Chromo PF00385.19 EMC82091.1 - 4.2e-11 42.3 1.0 4.2e-11 42.3 0.7 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PDGF PF00341.12 EMC82092.1 - 2.2e-23 82.1 12.4 3.6e-23 81.4 8.6 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.8 EMC82092.1 - 1.7e-19 70.1 2.7 3.2e-19 69.2 0.2 2.3 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Ribosomal_L3 PF00297.17 EMC82093.1 - 3.7e-123 410.0 9.9 4.5e-123 409.7 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3903 PF13043.1 EMC82093.1 - 0.034 13.6 0.9 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) PP2C PF00481.16 EMC82094.1 - 5.8e-38 130.7 0.0 1.1e-37 129.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C MARVEL PF01284.18 EMC82094.1 - 2.5e-21 76.0 2.4 4e-21 75.3 1.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain Glyco_transf_17 PF04724.8 EMC82096.1 - 6.8e-131 436.4 0.0 8.9e-131 436.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 hEGF PF12661.2 EMC82096.1 - 0.0064 16.4 3.7 0.022 14.8 2.5 2.0 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 EMC82096.1 - 0.14 12.3 1.0 0.34 11.1 0.7 1.6 1 0 0 1 1 1 0 EGF-like domain Mab-21 PF03281.9 EMC82097.1 - 2.9e-33 115.2 0.0 6e-31 107.6 0.0 2.1 1 1 0 1 1 1 1 Mab-21 protein bZIP_1 PF00170.16 EMC82098.1 - 3e-14 52.6 16.0 3.3e-14 52.5 9.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EMC82098.1 - 4.6e-08 32.7 12.2 9.9e-08 31.6 8.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper IncA PF04156.9 EMC82098.1 - 0.0015 18.1 3.5 0.0023 17.5 2.4 1.2 1 0 0 1 1 1 1 IncA protein Phage_GPO PF05929.6 EMC82098.1 - 0.076 12.2 3.6 1.1 8.4 3.9 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase BLOC1_2 PF10046.4 EMC82098.1 - 0.17 12.0 4.3 0.35 11.0 3.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EMC82098.1 - 0.23 11.2 5.6 0.39 10.4 3.9 1.2 1 0 0 1 1 1 0 Laminin Domain II bZIP_Maf PF03131.12 EMC82098.1 - 0.25 11.6 8.8 0.45 10.8 6.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 EMC82098.1 - 2.3 7.2 9.8 3.3 6.6 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMC82098.1 - 8.5 4.0 6.7 12 3.6 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 EMC82098.1 - 9.6 5.7 11.3 17 4.9 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SH3_1 PF00018.23 EMC82100.1 - 1.6e-32 110.6 0.2 1.6e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC82100.1 - 5.9e-32 109.0 0.1 2.7e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.19 EMC82100.1 - 1.1e-21 76.3 0.7 1.8e-21 75.7 0.5 1.3 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.12 EMC82100.1 - 1.5e-21 75.6 0.0 3.3e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2_2 PF14633.1 EMC82100.1 - 0.017 14.1 0.2 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 SH2 domain DUF1669 PF07894.7 EMC82101.1 - 3e-106 354.7 0.0 4.5e-106 354.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 EMC82101.1 - 4e-07 29.8 0.0 7.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain Ago_hook PF10427.4 EMC82102.1 - 1.4e-12 47.9 30.7 1.4e-12 47.9 21.3 10.6 4 2 6 10 10 10 1 Argonaute hook RRM_5 PF13893.1 EMC82102.1 - 4.8e-05 23.1 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC82102.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82102.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.13 EMC82103.1 - 4.2e-48 163.6 1.4 6.2e-48 163.1 0.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.14 EMC82103.1 - 3.3e-30 104.5 0.2 7.6e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.23 EMC82103.1 - 2.7e-12 45.8 0.1 7.4e-12 44.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC82103.1 - 9.5e-11 41.1 0.0 2.8e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC82103.1 - 5.3e-10 38.6 0.0 1.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RPEL PF02755.10 EMC82104.1 - 8.3e-20 69.4 2.5 6.1e-09 34.9 0.0 2.7 2 0 0 2 2 2 2 RPEL repeat SAP PF02037.22 EMC82104.1 - 4.9e-12 45.0 0.5 1.1e-11 43.9 0.4 1.6 1 0 0 1 1 1 1 SAP domain Mito_carr PF00153.22 EMC82105.1 - 1.7e-53 178.3 0.3 4.3e-23 80.8 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 EMC82106.1 - 7.1e-25 86.4 2.2 4.5e-14 51.8 0.1 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EMC82106.1 - 2.5e-13 48.9 1.3 2e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC82106.1 - 3.4e-12 45.2 8.9 0.0038 17.0 0.9 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC82106.1 - 4.2e-10 40.0 3.4 1.5e-06 28.7 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC82106.1 - 6.5e-07 29.0 0.1 0.0017 18.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC82106.1 - 1.8e-06 27.6 2.3 2.5e-06 27.2 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC82106.1 - 7e-06 26.2 3.9 0.054 14.1 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC82106.1 - 0.00028 20.7 4.4 0.0089 15.9 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC82106.1 - 0.0011 19.3 1.1 0.039 14.2 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC82106.1 - 0.0072 16.7 0.1 33 5.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC82106.1 - 0.027 14.2 0.3 15 5.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC82106.1 - 0.37 10.7 3.3 31 4.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4175 PF13779.1 EMC82106.1 - 2.4 5.7 15.4 0.011 13.5 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) NYD-SP12_N PF15015.1 EMC82106.1 - 4.7 5.3 12.3 0.2 9.8 0.1 2.4 1 1 2 3 3 3 0 Spermatogenesis-associated, N-terminal DUF3216 PF11505.3 EMC82106.1 - 5.1 6.9 7.9 10 5.9 2.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3216) DUF2203 PF09969.4 EMC82106.1 - 7.1 6.8 9.1 0.56 10.4 2.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_M24 PF00557.19 EMC82108.1 - 1.4e-55 188.1 0.0 1.8e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMC82108.1 - 4.5e-37 126.4 0.0 1e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain zf-rbx1 PF12678.2 EMC82109.1 - 3.1e-33 113.6 14.5 3.6e-33 113.5 10.0 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC82109.1 - 4.2e-16 58.5 10.6 5e-16 58.3 7.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMC82109.1 - 7.1e-08 32.1 12.8 5.7e-07 29.2 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC82109.1 - 0.00033 20.2 12.2 0.0072 15.9 8.5 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC82109.1 - 0.00058 19.4 10.4 0.0028 17.2 3.2 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC82109.1 - 0.0087 16.0 12.7 0.37 10.8 8.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMC82109.1 - 0.11 12.4 9.3 0.74 9.8 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EMC82109.1 - 0.22 11.2 12.9 2.5 7.9 8.9 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC82109.1 - 0.25 11.0 7.2 0.4 10.4 1.7 2.2 1 1 1 2 2 2 0 RING-type zinc-finger DUF4001 PF13165.1 EMC82109.1 - 0.42 10.3 5.0 0.61 9.7 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) zf-HC5HC2H_2 PF13832.1 EMC82109.1 - 2 8.4 11.5 5.7 6.9 7.9 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC82109.1 - 4.2 7.5 12.4 2.4e+02 1.9 8.6 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 EMC82109.1 - 9 6.2 9.9 0.51 10.2 0.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING TrwC PF08751.6 EMC82110.1 - 0.034 13.5 0.3 0.044 13.2 0.2 1.1 1 0 0 1 1 1 0 TrwC relaxase DUF411 PF04214.8 EMC82110.1 - 0.3 10.5 1.6 20 4.7 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF 7tm_4 PF13853.1 EMC82112.1 - 7.6e-32 110.0 8.3 8.8e-32 109.8 5.7 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC82112.1 - 2.7e-13 49.6 2.1 3.2e-13 49.3 1.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.17 EMC82114.1 - 3.1e-06 26.7 0.0 3.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82114.1 - 0.055 13.4 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) I-set PF07679.11 EMC82115.1 - 3.2e-27 94.2 0.0 4.1e-15 55.4 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82115.1 - 2.1e-20 72.6 0.1 9e-10 38.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC82115.1 - 2.2e-14 53.6 0.1 4.1e-09 36.8 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC82115.1 - 5e-12 45.7 0.0 7.9e-05 22.7 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC82115.1 - 7.9e-09 35.4 0.5 5.7e-05 22.9 0.0 3.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain Kazal_2 PF07648.10 EMC82115.1 - 1.2e-08 34.6 5.0 3.6e-08 33.2 3.4 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC82115.1 - 6.2e-06 26.1 11.2 1.6e-05 24.8 7.8 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.27 EMC82115.1 - 3.8e-05 22.6 0.5 0.00012 21.1 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EMC82115.1 - 7.7e-05 22.2 0.6 0.0012 18.5 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EMC82115.1 - 0.0011 19.0 6.1 0.0015 18.6 2.9 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC82115.1 - 0.0036 16.8 1.8 0.0044 16.5 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC82115.1 - 0.0039 17.1 1.0 0.01 15.8 0.7 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1-set PF07654.10 EMC82116.1 - 2.4e-30 104.3 1.0 2.5e-30 104.2 0.7 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC82116.1 - 2.3e-05 24.1 0.3 3e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC82116.1 - 0.00019 21.5 1.2 0.0003 20.8 0.8 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC82116.1 - 0.0013 18.5 0.1 0.0016 18.2 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82116.1 - 0.0016 18.5 0.2 0.0018 18.3 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Marek_A PF02124.10 EMC82116.1 - 0.017 14.5 0.0 0.02 14.3 0.0 1.0 1 0 0 1 1 1 0 Marek's disease glycoprotein A Ig_3 PF13927.1 EMC82116.1 - 0.04 14.4 0.8 0.093 13.2 0.5 1.6 1 1 0 1 1 1 0 Immunoglobulin domain DUF4448 PF14610.1 EMC82116.1 - 0.071 12.5 0.0 0.078 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Collagen PF01391.13 EMC82117.1 - 8.8e-10 37.9 5.1 1.7e-05 24.2 3.5 2.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M30 PF10460.4 EMC82118.1 - 1.7 7.4 8.6 0.45 9.3 0.9 2.2 2 0 0 2 2 2 0 Peptidase M30 Ank_2 PF12796.2 EMC82119.1 - 2.9e-91 299.9 17.7 3.3e-17 62.6 0.4 8.2 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMC82119.1 - 6.2e-85 275.0 20.8 2.7e-09 36.3 0.0 15.0 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.1 EMC82119.1 - 9.5e-69 220.4 19.2 6.8e-06 25.8 0.0 16.2 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 EMC82119.1 - 8.9e-65 214.0 18.1 7.7e-10 39.0 0.1 10.3 6 3 7 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC82119.1 - 2.1e-63 208.9 14.5 4.6e-08 33.0 0.0 13.4 3 3 10 13 13 13 13 Ankyrin repeats (many copies) Ion_trans PF00520.26 EMC82119.1 - 1.2e-08 34.4 24.5 2.5e-08 33.4 17.0 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 EMC82119.1 - 6.8e-06 24.7 17.9 0.0052 15.2 8.2 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF1843 PF08898.5 EMC82119.1 - 0.19 11.7 1.0 10 6.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) BTB_2 PF02214.17 EMC82120.1 - 3.8e-34 116.7 0.0 7.1e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kv2channel PF03521.9 EMC82121.1 - 2e-117 391.8 10.8 2e-117 391.8 7.5 1.7 2 0 0 2 2 2 1 Kv2 voltage-gated K+ channel Ion_trans PF00520.26 EMC82121.1 - 5e-36 123.8 8.3 7.8e-36 123.2 5.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EMC82121.1 - 1.5e-11 43.8 4.7 1.5e-11 43.8 3.2 1.8 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC82121.1 - 0.061 11.7 3.2 0.1 11.0 2.3 1.3 1 0 0 1 1 1 0 Polycystin cation channel TRF PF08558.5 EMC82123.1 - 6e-28 97.7 0.8 9.3e-28 97.1 0.5 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EMC82123.1 - 1.8e-09 37.5 0.3 4.6e-09 36.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC82123.1 - 7.3e-05 22.7 0.7 0.00026 21.0 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPR_7 PF13176.1 EMC82123.1 - 0.013 15.2 0.0 0.039 13.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC82123.1 - 0.047 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TSP_1 PF00090.14 EMC82124.1 - 0.0017 18.4 2.2 0.0017 18.4 1.5 2.5 2 1 0 2 2 2 1 Thrombospondin type 1 domain Ribosomal_L30_N PF08079.7 EMC82125.1 - 1.5e-25 88.9 17.6 2.7e-25 88.1 12.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EMC82125.1 - 6.1e-22 76.9 0.9 1.6e-21 75.5 0.6 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e adh_short PF00106.20 EMC82127.1 - 0.0008 19.3 0.0 0.00099 19.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Ion_trans_2 PF07885.11 EMC82130.1 - 1.5e-39 133.5 29.0 2.1e-19 69.0 1.5 4.0 3 1 1 4 4 4 3 Ion channel bZIP_Maf PF03131.12 EMC82130.1 - 0.005 17.1 0.6 0.0093 16.2 0.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4079 PF13301.1 EMC82130.1 - 0.012 15.6 2.0 0.015 15.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) fn3 PF00041.16 EMC82131.1 - 2.2e-239 774.4 92.0 1.7e-12 47.3 0.5 36.8 36 1 0 36 36 36 34 Fibronectin type III domain Laminin_EGF PF00053.19 EMC82131.1 - 2.5e-77 254.6 190.9 5.8e-09 35.7 11.6 10.9 10 0 0 10 10 10 10 Laminin EGF-like (Domains III and V) Laminin_G_2 PF02210.19 EMC82131.1 - 8.7e-46 155.1 0.5 1.1e-20 73.9 0.0 3.8 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 EMC82131.1 - 1.8e-35 121.8 0.1 9.7e-17 61.2 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.1 EMC82131.1 - 1.9e-18 67.2 0.1 6e-11 42.8 0.0 4.0 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily ChitinaseA_N PF08329.5 EMC82131.1 - 1.1e-12 47.8 7.7 4 7.2 0.1 13.8 14 1 1 15 15 15 3 Chitinase A, N-terminal domain PhoD PF09423.5 EMC82131.1 - 0.78 8.2 1.2 27 3.1 0.0 4.0 4 1 0 4 4 4 0 PhoD-like phosphatase DUF1469 PF07332.6 EMC82131.1 - 5.6 6.7 0.1 9.8 5.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Hormone_recep PF00104.25 EMC82132.1 - 3.3e-36 124.3 0.3 4.7e-36 123.8 0.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC82132.1 - 5.5e-31 106.6 12.3 1.1e-30 105.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GAT PF03127.9 EMC82132.1 - 0.1 12.5 1.1 6.4 6.8 0.1 2.4 2 0 0 2 2 2 0 GAT domain I-set PF07679.11 EMC82133.1 - 2.3e-61 203.6 0.3 9.2e-12 44.6 0.0 8.3 7 1 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82133.1 - 1.2e-51 172.7 0.0 2.4e-09 37.1 0.0 6.5 5 1 1 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 EMC82133.1 - 2.2e-45 152.6 10.0 8.1e-17 61.1 0.6 4.9 4 0 0 4 4 4 4 Fibronectin type III domain Ig_3 PF13927.1 EMC82133.1 - 2.5e-38 130.3 0.0 1e-06 29.1 0.0 7.5 8 0 0 8 8 7 6 Immunoglobulin domain V-set PF07686.12 EMC82133.1 - 1.4e-33 115.1 2.1 1.3e-06 28.2 0.0 8.7 7 3 2 9 9 8 5 Immunoglobulin V-set domain ig PF00047.20 EMC82133.1 - 1.5e-29 101.8 0.0 6e-05 23.0 0.0 6.9 6 1 0 6 6 6 6 Immunoglobulin domain Interfer-bind PF09294.5 EMC82133.1 - 5.6e-06 26.3 0.0 0.0018 18.2 0.1 3.5 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III C2-set_2 PF08205.7 EMC82133.1 - 0.00011 21.9 0.0 2 8.3 0.0 3.9 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Sp38 PF07354.7 EMC82133.1 - 0.003 16.2 0.0 2.6 6.6 0.0 3.3 4 0 0 4 4 4 2 Zona-pellucida-binding protein (Sp38) Tissue_fac PF01108.12 EMC82133.1 - 0.0064 16.2 4.4 0.82 9.4 0.0 4.6 3 2 1 4 4 4 1 Tissue factor Big_3_4 PF13754.1 EMC82133.1 - 0.024 14.9 0.4 1 9.7 0.0 3.6 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) PDZ PF00595.19 EMC82134.1 - 2.3e-20 72.5 0.2 1.5e-15 57.0 0.0 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC82134.1 - 7e-08 32.2 0.0 2.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 EMC82134.1 - 0.0038 16.9 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Glyco_transf_8 PF01501.15 EMC82135.1 - 2.3e-11 43.4 0.5 4.1e-11 42.6 0.3 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 RRM_1 PF00076.17 EMC82136.1 - 2.3e-22 78.4 0.2 3.8e-22 77.7 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82136.1 - 4.8e-19 68.1 0.1 8.3e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82136.1 - 4.4e-14 52.0 0.2 7.3e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EMC82136.1 - 0.0001 22.0 1.6 0.00018 21.2 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Limkain-b1 PF11608.3 EMC82136.1 - 0.018 14.7 0.3 0.084 12.6 0.2 2.1 1 1 0 1 1 1 0 Limkain b1 zf-CCHC_3 PF13917.1 EMC82136.1 - 0.021 14.5 0.9 0.041 13.6 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle SET_assoc PF11767.3 EMC82136.1 - 0.072 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF4661 PF15576.1 EMC82136.1 - 0.25 10.9 1.5 0.39 10.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) FAM176 PF14851.1 EMC82136.1 - 0.8 9.3 3.9 1.2 8.7 2.7 1.4 1 0 0 1 1 1 0 FAM176 family Lge1 PF11488.3 EMC82137.1 - 1.9e-16 60.0 0.4 4.3e-16 58.8 0.3 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 DUF3614 PF12267.3 EMC82137.1 - 0.24 11.6 6.4 0.39 10.9 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) PET PF06297.9 EMC82138.1 - 4.4e-44 148.4 0.1 9.7e-44 147.3 0.1 1.6 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 EMC82138.1 - 2.7e-25 88.1 40.0 9.9e-10 38.3 2.1 3.6 3 0 0 3 3 3 3 LIM domain Vasculin PF15337.1 EMC82138.1 - 0.0033 17.8 2.2 0.0069 16.8 0.0 2.5 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 TruD PF01142.13 EMC82139.1 - 6.6e-58 196.1 0.0 9.5e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) R3H PF01424.17 EMC82139.1 - 0.0011 18.6 0.3 0.033 13.8 0.0 3.0 3 1 0 3 3 3 1 R3H domain TMEM117 PF15113.1 EMC82140.1 - 1.7e-244 810.9 26.4 1.9e-244 810.7 18.3 1.0 1 0 0 1 1 1 1 TMEM117 protein family DUF202 PF02656.10 EMC82140.1 - 2.1 8.6 5.8 4.1 7.7 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) 7tm_1 PF00001.16 EMC82141.1 - 6.6e-35 120.4 23.0 6.6e-35 120.4 16.0 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Sigma_reg_N PF13800.1 EMC82141.1 - 3.2 7.8 0.0 3.2 7.8 0.0 4.1 4 1 1 5 5 5 0 Sigma factor regulator N-terminal EGF_CA PF07645.10 EMC82142.1 - 5.1e-29 99.9 65.3 1.4e-11 44.1 4.8 10.9 9 2 1 10 10 8 5 Calcium-binding EGF domain VWC PF00093.13 EMC82142.1 - 3.8e-18 65.3 64.8 2.5e-10 40.3 11.0 10.3 6 1 1 7 7 5 5 von Willebrand factor type C domain EGF_3 PF12947.2 EMC82142.1 - 5.1e-15 55.1 36.4 6e-09 35.7 9.8 10.9 11 1 0 11 11 10 4 EGF domain cEGF PF12662.2 EMC82142.1 - 1.3e-09 37.5 12.6 2.1e-08 33.6 2.4 11.2 10 0 0 10 10 10 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.19 EMC82142.1 - 4.1e-08 33.3 0.1 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 EMC82142.1 - 7.1e-06 25.8 38.1 0.00055 19.8 7.3 11.5 14 0 0 14 14 12 6 EGF-like domain Laminin_G_3 PF13385.1 EMC82142.1 - 1.3e-05 25.4 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 EMC82142.1 - 0.00022 21.2 0.0 0.00054 19.9 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain EGF_MSP1_1 PF12946.2 EMC82142.1 - 0.0003 20.5 8.4 0.0003 20.5 5.8 8.7 9 0 0 9 9 8 3 MSP1 EGF domain 1 FXa_inhibition PF14670.1 EMC82142.1 - 0.012 15.6 7.0 0.012 15.6 4.9 10.8 8 2 3 11 11 9 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 EMC82142.1 - 0.02 14.9 0.8 0.02 14.9 0.6 11.8 11 0 0 11 11 10 0 Human growth factor-like EGF Hormone_1 PF00103.15 EMC82143.1 - 2.6e-29 102.1 8.3 6.1e-15 55.1 0.4 2.4 1 1 1 2 2 2 2 Somatotropin hormone family DUF4600 PF15372.1 EMC82143.1 - 0.096 12.9 0.4 0.69 10.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Homeobox PF00046.24 EMC82144.1 - 1.4e-21 75.8 5.3 2.8e-21 74.8 3.7 1.5 1 0 0 1 1 1 1 Homeobox domain DUF2986 PF11661.3 EMC82144.1 - 0.0016 18.7 0.5 0.0016 18.7 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homez PF11569.3 EMC82144.1 - 0.068 12.2 0.7 0.15 11.1 0.2 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC82144.1 - 0.12 12.1 0.4 0.34 10.6 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain Anoctamin PF04547.7 EMC82145.1 - 1.9e-147 491.5 21.1 2.4e-147 491.2 14.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Halogen_Hydrol PF10112.4 EMC82145.1 - 0.023 14.1 0.7 0.023 14.1 0.5 3.0 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ctr PF04145.10 EMC82145.1 - 0.032 14.2 2.8 8.6 6.4 0.2 3.3 3 0 0 3 3 3 0 Ctr copper transporter family Glycophorin_A PF01102.13 EMC82145.1 - 0.19 11.4 0.2 22 4.8 0.0 2.6 2 0 0 2 2 2 0 Glycophorin A SPT6_acidic PF14632.1 EMC82145.1 - 0.48 10.6 5.4 8.7 6.5 0.6 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Aa_trans PF01490.13 EMC82147.1 - 4.2e-78 262.6 39.7 4.9e-78 262.4 27.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4234 PF14018.1 EMC82147.1 - 0.068 12.9 2.4 0.45 10.2 1.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Herpes_US9 PF06072.6 EMC82147.1 - 0.66 9.8 0.0 0.66 9.8 0.0 3.2 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Aa_trans PF01490.13 EMC82149.1 - 1.3e-72 244.5 34.4 3e-46 157.7 9.1 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4234 PF14018.1 EMC82149.1 - 2.9 7.6 9.2 0.41 10.4 1.6 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) LRR_8 PF13855.1 EMC82151.1 - 6.7e-23 80.2 13.0 6.3e-14 51.4 4.0 4.1 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EMC82151.1 - 1.5e-17 62.8 14.8 4.2e-09 35.8 1.0 4.1 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC82151.1 - 1.5e-10 39.5 22.4 0.071 13.1 0.2 7.9 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 EMC82151.1 - 9.2e-08 31.0 13.7 0.05 13.8 0.3 7.0 6 0 0 6 6 6 1 Leucine rich repeat LRR_5 PF13306.1 EMC82151.1 - 3e-07 30.2 0.9 6.8e-07 29.0 0.6 1.5 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC82151.1 - 4.1e-07 29.3 12.5 1.3 9.3 0.1 6.8 6 0 0 6 6 6 2 Leucine Rich repeat V-set PF07686.12 EMC82151.1 - 1.9e-06 27.7 0.0 4.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 EMC82151.1 - 5.5e-05 22.8 0.4 0.036 13.6 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat I-set PF07679.11 EMC82151.1 - 0.00018 21.3 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82151.1 - 0.0012 18.8 0.0 0.0042 17.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 EMC82151.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRRNT PF01462.13 EMC82151.1 - 0.0033 16.8 2.5 0.0033 16.8 1.7 3.2 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Ig_3 PF13927.1 EMC82151.1 - 0.01 16.3 0.2 0.1 13.1 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin domain DUF261 PF03196.8 EMC82151.1 - 0.06 13.3 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF261 TPR_11 PF13414.1 EMC82152.1 - 3.1e-48 161.2 37.0 7.9e-18 63.8 0.2 4.4 2 2 4 6 6 6 6 TPR repeat TPR_1 PF00515.23 EMC82152.1 - 5.2e-36 120.7 26.0 3.6e-06 26.3 0.2 7.0 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMC82152.1 - 1.9e-28 96.0 25.7 5.7e-05 22.7 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat RPAP3_C PF13877.1 EMC82152.1 - 7.4e-28 96.3 1.3 2.2e-27 94.8 0.9 1.8 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_7 PF13176.1 EMC82152.1 - 2.7e-15 54.8 8.3 6.2e-05 22.4 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC82152.1 - 3.1e-15 56.3 14.5 0.0053 17.3 0.2 5.6 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMC82152.1 - 7.7e-13 48.1 5.7 0.00045 20.0 0.2 4.9 4 2 2 6 6 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC82152.1 - 3.3e-12 45.2 19.2 0.029 14.1 0.3 7.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC82152.1 - 1.6e-11 43.7 4.3 0.063 13.9 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC82152.1 - 2.8e-09 36.7 18.8 0.044 13.7 1.9 5.0 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC82152.1 - 4.1e-08 33.4 12.0 0.0092 16.2 1.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC82152.1 - 5e-06 26.3 22.8 0.053 13.7 0.2 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC82152.1 - 0.00072 19.8 12.3 6.7 7.3 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.13 EMC82152.1 - 0.00082 19.2 5.3 0.14 12.0 0.2 3.9 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 EMC82152.1 - 0.0014 18.7 9.0 0.044 13.9 0.4 3.6 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EMC82152.1 - 0.033 14.1 3.2 11 6.2 0.1 4.5 5 0 0 5 5 4 0 PPR repeat Fis1_TPR_C PF14853.1 EMC82152.1 - 0.089 12.6 20.5 0.12 12.2 0.0 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Reprolysin_5 PF13688.1 EMC82152.1 - 0.094 12.6 0.1 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12 RPN7 PF10602.4 EMC82152.1 - 0.13 11.6 0.0 0.13 11.6 0.0 3.9 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 EMC82152.1 - 6 6.9 10.1 84 3.2 0.2 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat MutS_IV PF05190.13 EMC82152.1 - 8.5 6.6 15.3 0.072 13.2 1.7 3.5 4 0 0 4 4 3 0 MutS family domain IV Peptidase_M76 PF09768.4 EMC82153.1 - 3.4e-63 212.2 7.9 4e-63 211.9 5.5 1.0 1 0 0 1 1 1 1 Peptidase M76 family Ribosomal_60s PF00428.14 EMC82153.1 - 1.4 9.4 8.7 0.23 11.8 3.5 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein ECH PF00378.15 EMC82154.1 - 9.3e-52 175.5 0.1 1e-51 175.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SARG PF15385.1 EMC82155.1 - 2.4e-73 248.1 43.4 3.1e-71 241.2 30.1 3.1 1 1 0 1 1 1 1 Specifically androgen-regulated gene protein MIF4G PF02854.14 EMC82156.1 - 1.6e-78 262.9 10.5 5.6e-41 140.2 0.0 3.7 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EMC82156.1 - 7.6e-46 155.9 20.2 7.6e-46 155.9 14.0 5.7 4 2 1 5 5 5 1 Up-frameshift suppressor 2 Transket_pyr PF02779.19 EMC82157.1 - 1e-62 210.7 0.0 1.7e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EMC82157.1 - 5.8e-44 150.0 0.0 1e-43 149.1 0.0 1.4 1 1 0 1 1 1 1 Dehydrogenase E1 component SecY PF00344.15 EMC82158.1 - 2.6e-93 312.7 13.8 3.5e-93 312.2 9.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMC82158.1 - 1.3e-19 69.3 0.3 4.3e-19 67.7 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p YlaH PF14036.1 EMC82158.1 - 0.17 12.0 5.5 1.3 9.1 0.1 3.2 3 0 0 3 3 3 0 YlaH-like protein NUDIX PF00293.23 EMC82159.1 - 1.2e-17 63.7 0.6 2e-17 63.0 0.1 1.6 2 0 0 2 2 2 1 NUDIX domain D123 PF07065.9 EMC82160.1 - 4.5e-114 380.5 0.0 5.1e-114 380.3 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EMC82160.1 - 4e-05 23.4 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) DUF466 PF04328.8 EMC82160.1 - 0.084 12.7 0.3 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF466) ATPgrasp_YheCD PF14398.1 EMC82160.1 - 0.098 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Pkinase PF00069.20 EMC82161.1 - 3e-56 190.4 0.0 4.2e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82161.1 - 2.7e-21 75.8 0.0 3.6e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC82161.1 - 1.6e-07 30.5 0.0 2.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC82161.1 - 0.00075 18.6 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC82161.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EMC82161.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EMC82161.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YscO PF07321.7 EMC82163.1 - 9.7e-07 28.7 9.5 1.4e-06 28.2 6.6 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO Myosin_tail_1 PF01576.14 EMC82163.1 - 5.5e-05 21.1 4.8 6.3e-05 20.9 3.3 1.0 1 0 0 1 1 1 1 Myosin tail bZIP_1 PF00170.16 EMC82163.1 - 0.00086 19.2 3.4 0.00086 19.2 2.4 1.9 1 1 1 2 2 2 1 bZIP transcription factor BLOC1_2 PF10046.4 EMC82163.1 - 0.00095 19.2 1.1 0.0016 18.5 0.8 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EMC82163.1 - 0.0014 18.4 3.1 0.0018 18.0 2.1 1.1 1 0 0 1 1 1 1 Laminin Domain II Fib_alpha PF08702.5 EMC82163.1 - 0.0015 18.6 3.1 0.0029 17.7 2.2 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family KLRAQ PF10205.4 EMC82163.1 - 0.0018 18.2 8.1 0.0025 17.8 5.6 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.2 EMC82163.1 - 0.002 17.9 8.8 0.0027 17.5 6.1 1.1 1 0 0 1 1 1 1 Tropomyosin like AAA_13 PF13166.1 EMC82163.1 - 0.0025 16.3 1.9 0.0035 15.8 1.3 1.1 1 0 0 1 1 1 1 AAA domain Cluap1 PF10234.4 EMC82163.1 - 0.0029 16.8 4.8 0.0032 16.7 3.4 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Herpes_UL6 PF01763.11 EMC82163.1 - 0.0029 15.8 3.0 0.003 15.8 2.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like Mnd1 PF03962.10 EMC82163.1 - 0.0032 17.1 2.9 0.0032 17.1 2.0 1.1 1 0 0 1 1 1 1 Mnd1 family DUF1664 PF07889.7 EMC82163.1 - 0.0041 16.9 3.3 0.0056 16.4 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EMC82163.1 - 0.0041 16.9 0.9 0.0041 16.9 0.6 1.6 2 0 0 2 2 1 1 Flagella accessory protein C (FlaC) Atg14 PF10186.4 EMC82163.1 - 0.0043 16.0 6.4 0.0046 15.9 4.5 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EMC82163.1 - 0.0046 16.5 5.9 0.0058 16.2 4.1 1.1 1 0 0 1 1 1 1 IncA protein DUF489 PF04356.7 EMC82163.1 - 0.0066 16.0 1.7 0.0084 15.7 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) RRF_GI PF12614.3 EMC82163.1 - 0.0088 15.8 2.6 0.015 15.1 1.7 1.5 1 1 0 1 1 1 1 Ribosome recycling factor Laminin_I PF06008.9 EMC82163.1 - 0.0097 15.2 5.9 0.012 14.9 4.1 1.1 1 0 0 1 1 1 1 Laminin Domain I Striatin PF08232.7 EMC82163.1 - 0.011 15.9 4.3 0.015 15.6 3.0 1.3 1 0 0 1 1 1 0 Striatin family Spc7 PF08317.6 EMC82163.1 - 0.012 14.2 5.1 0.013 14.1 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.14 EMC82163.1 - 0.013 15.0 2.4 0.017 14.6 1.7 1.2 1 0 0 1 1 1 0 GrpE TMF_DNA_bd PF12329.3 EMC82163.1 - 0.015 15.0 9.3 0.022 14.5 6.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rabaptin PF03528.10 EMC82163.1 - 0.017 14.9 4.4 0.022 14.6 3.1 1.3 1 0 0 1 1 1 0 Rabaptin EMP24_GP25L PF01105.19 EMC82163.1 - 0.018 14.7 3.9 0.022 14.4 2.7 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF972 PF06156.8 EMC82163.1 - 0.019 15.2 4.6 0.029 14.7 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) EzrA PF06160.7 EMC82163.1 - 0.02 13.1 3.8 0.024 12.8 2.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Rootletin PF15035.1 EMC82163.1 - 0.02 14.8 7.6 0.024 14.6 5.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Snapin_Pallidin PF14712.1 EMC82163.1 - 0.023 15.0 3.3 0.036 14.3 2.3 1.4 1 0 0 1 1 1 0 Snapin/Pallidin DUF3450 PF11932.3 EMC82163.1 - 0.032 13.4 2.4 0.035 13.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 EMC82163.1 - 0.034 13.1 4.3 0.039 12.9 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 P4Ha_N PF08336.6 EMC82163.1 - 0.035 13.9 3.7 0.055 13.2 2.6 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PRKCSH-like PF12999.2 EMC82163.1 - 0.035 13.6 1.3 0.044 13.3 0.9 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Prominin PF05478.6 EMC82163.1 - 0.038 11.5 2.5 0.047 11.2 1.7 1.1 1 0 0 1 1 1 0 Prominin SpoVIF PF14069.1 EMC82163.1 - 0.039 13.6 2.9 0.083 12.6 2.0 1.6 1 1 0 1 1 1 0 Stage VI sporulation protein F NPV_P10 PF05531.7 EMC82163.1 - 0.041 14.1 2.2 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Herpes_U30 PF04523.8 EMC82163.1 - 0.042 11.3 1.2 0.061 10.7 0.8 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF3552 PF12072.3 EMC82163.1 - 0.044 12.9 8.6 0.054 12.7 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4570 PF15134.1 EMC82163.1 - 0.05 13.4 4.2 0.069 12.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) V_ATPase_I PF01496.14 EMC82163.1 - 0.05 11.4 4.6 0.057 11.2 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EMC82163.1 - 0.051 13.8 9.4 0.074 13.3 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Cauli_AT PF03233.8 EMC82163.1 - 0.056 13.1 2.4 0.076 12.7 1.7 1.4 1 0 0 1 1 1 0 Aphid transmission protein DivIC PF04977.10 EMC82163.1 - 0.057 12.9 7.9 0.094 12.2 5.3 1.5 1 1 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 EMC82163.1 - 0.072 12.9 8.7 0.094 12.5 6.1 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain HemX PF04375.9 EMC82163.1 - 0.079 11.5 4.3 0.091 11.3 3.0 1.2 1 0 0 1 1 1 0 HemX DegS PF05384.6 EMC82163.1 - 0.086 12.0 7.4 0.085 12.0 3.7 1.5 1 1 0 1 1 1 0 Sensor protein DegS TMPIT PF07851.8 EMC82163.1 - 0.094 11.7 3.7 0.12 11.3 2.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.6 EMC82163.1 - 0.12 11.0 4.3 0.15 10.7 3.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) ADIP PF11559.3 EMC82163.1 - 0.13 12.2 11.5 0.18 11.7 7.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Med4 PF10018.4 EMC82163.1 - 0.14 11.5 4.8 0.2 11.0 3.4 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2951 PF11166.3 EMC82163.1 - 0.14 11.9 7.7 0.56 10.0 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) COG2 PF06148.6 EMC82163.1 - 0.17 11.7 4.7 0.27 11.1 3.3 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Rab5-bind PF09311.6 EMC82163.1 - 0.18 11.6 10.4 0.24 11.2 7.2 1.1 1 0 0 1 1 1 0 Rabaptin-like protein SlyX PF04102.7 EMC82163.1 - 0.2 12.0 6.0 0.71 10.2 4.1 1.9 1 1 0 1 1 1 0 SlyX DUF2681 PF10883.3 EMC82163.1 - 0.22 11.7 6.9 0.34 11.1 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Prefoldin_2 PF01920.15 EMC82163.1 - 0.23 11.2 8.1 0.14 11.9 4.2 1.6 1 1 0 1 1 1 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 EMC82163.1 - 0.24 11.4 7.2 0.34 10.9 5.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Nnf1 PF03980.9 EMC82163.1 - 0.3 11.0 5.4 0.27 11.2 0.8 2.1 1 1 1 2 2 2 0 Nnf1 DUF342 PF03961.8 EMC82163.1 - 0.33 9.2 3.3 0.37 9.1 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3251 PF11622.3 EMC82163.1 - 0.45 9.9 3.5 0.6 9.4 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) Fzo_mitofusin PF04799.8 EMC82163.1 - 0.52 9.6 5.1 0.64 9.3 3.2 1.4 1 1 0 1 1 1 0 fzo-like conserved region DUF3373 PF11853.3 EMC82163.1 - 0.7 8.3 3.1 0.85 8.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Cep57_CLD_2 PF14197.1 EMC82163.1 - 0.98 9.4 9.4 1.7 8.6 6.5 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4446 PF14584.1 EMC82163.1 - 1.1 9.1 6.2 2.8 7.7 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Viral_P18 PF04521.8 EMC82163.1 - 1.1 8.7 6.2 1.6 8.1 4.3 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein XhlA PF10779.4 EMC82163.1 - 1.4 8.8 5.5 2.6 8.0 3.8 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Synaptobrevin PF00957.16 EMC82163.1 - 2 8.0 5.3 3.6 7.2 3.7 1.5 1 1 0 1 1 1 0 Synaptobrevin DUF724 PF05266.9 EMC82163.1 - 2.7 7.5 10.0 2.6 7.6 6.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FUSC-like PF12805.2 EMC82163.1 - 2.8 6.7 5.6 4 6.2 3.9 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS NEMO PF11577.3 EMC82164.1 - 1.8e-28 98.0 11.4 1.8e-28 98.0 7.9 5.5 6 1 0 6 6 6 2 NF-kappa-B essential modulator NEMO HALZ PF02183.13 EMC82164.1 - 0.0095 15.6 2.3 0.0095 15.6 1.6 7.3 8 0 0 8 8 8 2 Homeobox associated leucine zipper PMT_C PF11647.3 EMC82164.1 - 0.019 14.5 0.2 0.019 14.5 0.1 3.8 3 1 2 5 5 5 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Glyco_trans_1_2 PF13524.1 EMC82164.1 - 0.41 10.9 7.7 0.32 11.2 0.8 3.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 DUF4248 PF14053.1 EMC82164.1 - 1.7 8.2 5.0 2.7 7.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) Mcm10 PF09332.6 EMC82165.1 - 5.4e-133 443.6 9.3 5.4e-133 443.6 6.4 2.7 2 1 0 2 2 2 1 Mcm10 replication factor zf-primase PF09329.6 EMC82165.1 - 9e-18 63.6 2.2 2.7e-17 62.0 1.5 1.9 1 0 0 1 1 1 1 Primase zinc finger Allexi_40kDa PF05549.6 EMC82165.1 - 6.8 5.8 7.8 1.3 8.2 1.5 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein PhyH PF05721.8 EMC82166.1 - 1.8e-42 145.7 0.0 2.2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AIRS_C PF02769.17 EMC82168.1 - 2.2e-27 95.9 0.1 3.4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EMC82168.1 - 1.2e-11 44.6 0.1 2.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF2431 PF10354.4 EMC82168.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) BEN PF10523.4 EMC82169.1 - 2.1e-12 46.9 0.1 5.7e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 BEN domain Prp18 PF02840.10 EMC82170.1 - 9.7e-59 197.3 0.1 1.5e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 EMC82170.1 - 1e-13 50.2 3.9 1e-13 50.2 2.7 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Phage_int_SAM_4 PF13495.1 EMC82170.1 - 0.051 13.9 0.2 4.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain EB1 PF03271.12 EMC82170.1 - 0.12 12.4 0.2 0.43 10.6 0.1 1.9 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF3338 PF11819.3 EMC82171.1 - 1.5e-60 202.6 5.0 1.5e-60 202.6 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_M PF00373.13 EMC82171.1 - 5.6e-20 71.7 0.0 5.6e-20 71.7 0.0 3.1 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 EMC82171.1 - 2.2e-12 46.8 0.2 8.9e-12 44.9 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.5 EMC82171.1 - 7.8e-06 26.0 0.0 9.1e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 FERM C-terminal PH-like domain Myosin_tail_1 PF01576.14 EMC82172.1 - 1.2e-86 291.2 127.9 1e-80 271.6 41.8 3.8 1 1 2 3 3 3 3 Myosin tail Reo_sigmaC PF04582.7 EMC82172.1 - 1.2e-07 31.2 35.4 0.0057 15.8 2.3 4.7 1 1 5 6 6 6 6 Reovirus sigma C capsid protein IQ PF00612.22 EMC82172.1 - 7e-06 25.2 1.2 0.00016 21.0 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif IncA PF04156.9 EMC82172.1 - 0.001 18.7 120.0 0.026 14.0 19.2 5.9 1 1 6 7 7 7 6 IncA protein Filament PF00038.16 EMC82172.1 - 0.0013 18.2 105.5 0.0014 18.1 38.8 5.3 1 1 2 3 3 3 1 Intermediate filament protein GAS PF13851.1 EMC82172.1 - 0.0015 17.7 120.4 0.27 10.4 17.9 6.3 1 1 5 6 6 6 6 Growth-arrest specific micro-tubule binding DUF869 PF05911.6 EMC82172.1 - 0.0036 15.6 3.9 0.0036 15.6 2.7 4.4 1 1 3 4 4 4 2 Plant protein of unknown function (DUF869) Tektin PF03148.9 EMC82172.1 - 0.0061 15.1 12.1 0.0061 15.1 8.4 5.9 1 1 5 6 6 6 2 Tektin family TPR_MLP1_2 PF07926.7 EMC82172.1 - 0.0091 15.7 9.4 0.0091 15.7 6.5 6.1 2 1 4 6 6 6 2 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.1 EMC82172.1 - 0.021 14.9 6.2 0.021 14.9 4.3 9.5 4 3 4 8 8 7 0 Leucine-zipper of ternary complex factor MIP1 APG6 PF04111.7 EMC82172.1 - 0.79 8.7 115.5 0.47 9.4 17.2 5.2 1 1 4 5 5 5 0 Autophagy protein Apg6 AAA_13 PF13166.1 EMC82172.1 - 1.8 6.8 92.6 0.12 10.7 24.2 3.9 1 1 3 4 4 4 0 AAA domain Fib_alpha PF08702.5 EMC82172.1 - 2.1 8.4 75.3 0.05 13.7 8.8 5.3 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 EMC82172.1 - 3.2 7.6 108.3 0.08 12.8 13.9 6.7 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EMC82172.1 - 4.4 7.0 108.3 0.83 9.4 14.0 6.7 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) CCDC155 PF14662.1 EMC82172.1 - 5.4 6.5 116.2 2.7 7.5 21.2 4.5 1 1 2 4 4 3 0 Coiled-coil region of CCDC155 Myosin_head PF00063.16 EMC82173.1 - 3.6e-176 587.1 3.6 2.3e-125 419.2 1.5 2.0 1 1 1 2 2 2 2 Myosin head (motor domain) Myosin_N PF02736.14 EMC82173.1 - 1.1e-15 57.0 0.4 1.1e-15 57.0 0.3 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EMC82173.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMC82173.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EMC82173.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Cupin_3 PF05899.7 EMC82173.1 - 0.024 13.9 0.1 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AAA_29 PF13555.1 EMC82173.1 - 0.073 12.6 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EMC82173.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Myosin_N PF02736.14 EMC82174.1 - 7.2e-13 47.9 0.3 1.1e-12 47.4 0.2 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.14 EMC82175.1 - 0 1049.3 278.5 0 1033.0 146.7 3.3 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 EMC82175.1 - 9.4e-272 903.1 1.1 9.4e-272 903.1 0.8 3.9 4 2 1 5 5 5 1 Myosin head (motor domain) Myosin_N PF02736.14 EMC82175.1 - 1.5e-15 56.5 1.2 4.6e-15 55.0 0.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 EMC82175.1 - 0.00016 21.0 76.1 0.0035 16.5 2.1 9.3 1 1 6 10 10 10 7 Reovirus sigma C capsid protein Filament PF00038.16 EMC82175.1 - 0.0063 16.0 232.3 0.0043 16.5 39.5 7.9 1 1 5 7 7 7 3 Intermediate filament protein IQ PF00612.22 EMC82175.1 - 0.012 15.1 2.8 0.048 13.3 0.4 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.1 EMC82175.1 - 0.2 11.7 0.0 0.2 11.7 0.0 5.5 4 1 0 4 4 4 0 AAA domain Myosin_tail_1 PF01576.14 EMC82176.1 - 7e-289 960.3 264.2 3.2e-288 958.1 143.5 2.7 1 1 1 3 3 3 3 Myosin tail Myosin_head PF00063.16 EMC82176.1 - 1e-264 879.8 1.2 1e-264 879.8 0.8 4.7 2 1 3 6 6 6 1 Myosin head (motor domain) Myosin_N PF02736.14 EMC82176.1 - 4.7e-10 38.9 3.3 1.5e-09 37.3 2.3 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.22 EMC82176.1 - 0.0042 16.5 1.2 0.096 12.3 0.0 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 EMC82176.1 - 1.4 8.0 71.0 0.28 10.3 1.0 9.3 1 1 8 10 10 10 0 Reovirus sigma C capsid protein SCO1-SenC PF02630.9 EMC82177.1 - 2.7e-37 128.0 0.0 3.1e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EMC82177.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EMC82177.1 - 0.00033 20.7 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Metallophos PF00149.23 EMC82178.1 - 0.0022 17.4 0.2 0.0027 17.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ELYS PF13934.1 EMC82180.1 - 4.1e-06 26.7 0.0 9.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore complex assembly DTW PF03942.10 EMC82182.1 - 7.4e-51 172.2 0.0 9.7e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 DTW domain FGF PF00167.13 EMC82183.1 - 1.8e-45 153.6 2.0 2.4e-45 153.2 1.4 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Ribosomal_L7Ae PF01248.21 EMC82185.1 - 4.7e-22 77.2 0.0 1.7e-21 75.5 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RrnaAD PF00398.15 EMC82185.1 - 0.0049 15.9 0.0 0.0089 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PID PF00640.18 EMC82186.1 - 1.2e-44 151.6 0.0 2.6e-44 150.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 EMC82186.1 - 5.6e-16 58.1 0.0 2.1e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 SH2 domain Myosin_tail_1 PF01576.14 EMC82187.1 - 4.2e-06 24.8 43.4 4.2e-06 24.8 30.1 2.4 2 0 0 2 2 2 1 Myosin tail TMF_DNA_bd PF12329.3 EMC82187.1 - 0.0032 17.2 13.7 0.0032 17.2 9.5 8.7 5 1 4 9 9 9 4 TATA element modulatory factor 1 DNA binding COX7a PF02238.10 EMC82187.1 - 0.062 13.0 1.0 3.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa ThiC-associated PF13667.1 EMC82188.1 - 0.067 12.7 0.0 21 4.7 0.0 3.4 3 0 0 3 3 3 0 ThiC-associated domain DUF3077 PF11275.3 EMC82188.1 - 0.13 12.2 0.6 0.33 10.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) EGF_CA PF07645.10 EMC82189.1 - 0 1062.3 724.8 2.1e-11 43.5 5.2 48.7 48 1 1 49 49 49 44 Calcium-binding EGF domain cEGF PF12662.2 EMC82189.1 - 1.7e-195 631.7 424.9 1e-08 34.6 0.6 49.8 50 0 0 50 50 50 44 Complement Clr-like EGF-like EGF PF00008.22 EMC82189.1 - 5e-132 429.0 664.1 1.1e-05 25.2 3.9 50.6 49 1 2 51 51 51 45 EGF-like domain TB PF00683.12 EMC82189.1 - 3e-121 394.7 137.1 4.5e-15 54.9 4.3 12.1 10 0 0 10 10 10 9 TB domain FXa_inhibition PF14670.1 EMC82189.1 - 5e-114 372.0 721.1 3.4e-10 39.8 6.4 49.3 44 4 6 50 50 50 44 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EMC82189.1 - 3e-57 190.2 623.5 1.4e-10 40.9 8.6 48.9 50 0 0 50 50 50 39 EGF domain Plasmod_Pvs28 PF06247.6 EMC82189.1 - 0.00014 21.4 19.2 0.00014 21.4 13.3 25.2 8 6 20 28 28 28 11 Plasmodium ookinete surface protein Pvs28 dUTPase PF00692.14 EMC82190.1 - 7.7e-48 161.1 0.0 9.1e-48 160.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase AA_permease PF00324.16 EMC82191.1 - 1.1e-148 495.5 38.4 1.3e-148 495.2 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.5 EMC82191.1 - 5.8e-25 86.4 0.0 1.5e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Amino acid permease N-terminal AA_permease_2 PF13520.1 EMC82191.1 - 1.9e-22 79.4 42.4 2.9e-22 78.8 29.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1682 PF07946.9 EMC82191.1 - 0.0054 15.6 0.4 0.01 14.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Cortexin PF11057.3 EMC82192.1 - 2.5e-40 135.9 0.1 2.7e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Cortexin of kidney RRM_1 PF00076.17 EMC82193.1 - 1.5e-57 191.1 0.8 3.7e-20 71.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82193.1 - 6.6e-37 125.3 0.5 1.3e-12 47.4 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82193.1 - 1e-21 76.5 0.5 8.6e-07 28.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC82193.1 - 5.1e-08 32.7 0.4 0.0012 18.6 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 EMC82193.1 - 2.9e-07 30.1 0.1 0.0032 17.1 0.0 2.8 2 1 0 2 2 2 2 Limkain b1 DUF3932 PF13068.1 EMC82193.1 - 0.019 15.0 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Na_Ca_ex PF01699.19 EMC82194.1 - 1.3e-48 164.1 30.9 1.1e-24 86.6 8.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SPC25 PF06703.6 EMC82194.1 - 8.6 5.9 9.0 4.3 6.9 0.9 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sema PF01403.14 EMC82195.1 - 1e-117 393.3 0.0 2.3e-117 392.1 0.0 1.5 1 1 0 1 1 1 1 Sema domain PSI PF01437.20 EMC82195.1 - 3.3e-07 30.3 2.1 7.8e-07 29.1 1.4 1.6 1 0 0 1 1 1 1 Plexin repeat PP1_bind PF15276.1 EMC82195.1 - 0.22 11.5 5.6 2.4 8.2 0.2 3.0 2 0 0 2 2 2 0 Protein phosphatase 1 binding OLF PF02191.11 EMC82196.1 - 2.2e-63 213.8 1.8 2.6e-63 213.6 1.3 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.13 EMC82196.1 - 6.3e-16 57.6 65.6 4.3e-10 38.9 19.0 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF758 PF05527.6 EMC82197.1 - 8.7e-98 325.3 5.7 9.6e-98 325.2 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Seadorna_VP6 PF07407.6 EMC82197.1 - 0.021 13.6 0.5 0.021 13.6 0.3 1.5 1 1 1 2 2 2 0 Seadornavirus VP6 protein DUF2408 PF10303.4 EMC82197.1 - 0.041 13.9 2.7 0.073 13.1 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) PFO_beta_C PF12367.3 EMC82197.1 - 0.064 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DALR_1 PF05746.10 EMC82197.1 - 0.12 12.3 2.0 0.18 11.7 1.1 1.5 1 1 0 1 1 1 0 DALR anticodon binding domain Adaptin_N PF01602.15 EMC82198.1 - 4.1e-86 289.4 5.4 5e-86 289.1 3.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.1 EMC82198.1 - 2.2e-36 124.2 0.0 6.8e-36 122.6 0.0 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.1 EMC82198.1 - 0.00052 20.2 0.0 1.1 9.6 0.0 4.1 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EMC82198.1 - 0.013 15.9 0.1 2.1 8.9 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat B2-adapt-app_C PF09066.5 EMC82198.1 - 0.04 13.7 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain DUF3227 PF11537.3 EMC82198.1 - 0.053 13.6 0.0 0.26 11.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3227) HEAT PF02985.17 EMC82198.1 - 0.057 13.5 0.0 10 6.4 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Coatomer_b_Cpla PF14806.1 EMC82198.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Cnd1 PF12717.2 EMC82198.1 - 0.13 12.1 2.6 5 6.9 0.0 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 SGIII PF15467.1 EMC82199.1 - 5.4e-219 727.8 32.2 6e-219 727.7 22.3 1.0 1 0 0 1 1 1 1 Secretogranin-3 DUF2680 PF10925.3 EMC82199.1 - 2.2e-07 30.6 5.2 0.26 11.1 0.1 4.5 3 1 1 4 4 4 3 Protein of unknown function (DUF2680) Phage_XkdX PF09693.5 EMC82199.1 - 0.032 13.7 0.2 8.1 6.0 0.1 3.4 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) DUF2201_N PF13203.1 EMC82199.1 - 0.11 11.6 7.3 0.026 13.6 2.4 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF1227 PF06777.6 EMC82199.1 - 0.22 11.1 7.1 0.96 9.1 0.1 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1227) Plasmid_stabil PF05016.9 EMC82199.1 - 0.58 10.5 3.1 1.8 9.0 0.1 3.0 3 1 1 4 4 4 0 Plasmid stabilisation system protein Hormone_2 PF00123.15 EMC82200.1 - 0.81 9.5 0.1 0.81 9.5 0.1 2.5 3 0 0 3 3 3 0 Peptide hormone Tropomodulin PF03250.9 EMC82201.1 - 1.6e-68 228.8 3.6 1.6e-68 228.8 2.5 1.7 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.1 EMC82201.1 - 0.063 13.3 2.5 0.5 10.6 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeat Ost4 PF10215.4 EMC82201.1 - 0.17 11.3 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase OmdA PF13376.1 EMC82201.1 - 0.33 10.6 1.7 14 5.4 0.0 3.3 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Tropomodulin PF03250.9 EMC82202.1 - 6.7e-67 223.5 4.2 1.5e-66 222.4 2.9 1.6 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.1 EMC82202.1 - 0.032 14.2 0.9 0.33 11.1 0.1 2.9 2 0 0 2 2 2 0 Leucine Rich repeat PARP_reg PF02877.9 EMC82202.1 - 0.076 12.6 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Leo1 PF04004.8 EMC82203.1 - 6.7e-56 188.6 0.0 6.7e-56 188.6 0.0 3.7 2 1 0 2 2 2 1 Leo1-like protein Ion_trans PF00520.26 EMC82204.1 - 1.6e-05 24.2 0.5 1.7e-05 24.2 0.4 1.0 1 0 0 1 1 1 1 Ion transport protein DUF423 PF04241.10 EMC82204.1 - 0.0043 16.9 0.4 0.0048 16.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DctQ PF04290.7 EMC82204.1 - 0.04 13.6 1.3 0.042 13.6 0.9 1.0 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component PKD_channel PF08016.7 EMC82204.1 - 0.1 11.0 0.5 0.099 11.0 0.3 1.0 1 0 0 1 1 1 0 Polycystin cation channel YueH PF14166.1 EMC82204.1 - 0.14 11.9 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 YueH-like protein Peptidase_C2 PF00648.16 EMC82205.1 - 9e-22 77.4 0.1 1e-21 77.2 0.1 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease 7tm_1 PF00001.16 EMC82207.1 - 2.8e-25 88.9 2.7 3.7e-25 88.5 1.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC82208.1 - 4.9e-62 207.9 10.5 4.9e-62 207.9 7.3 1.8 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC82208.1 - 6.3e-30 104.1 17.0 8e-30 103.8 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Nucleos_tra2_C PF07662.8 EMC82211.1 - 1.4e-71 240.3 4.7 3.5e-71 239.0 3.3 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EMC82211.1 - 9.2e-20 70.7 2.7 9.2e-20 70.7 1.8 3.1 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EMC82211.1 - 6.7e-06 25.9 8.5 6.7e-06 25.9 5.9 3.9 3 2 1 4 4 4 1 Nucleoside recognition DUF2265 PF10023.4 EMC82211.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) MIP-T3 PF10243.4 EMC82212.1 - 0.79 8.1 115.5 1.4 7.3 80.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1767 PF08585.7 EMC82213.1 - 1.2e-25 89.5 0.4 3.5e-25 88.0 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) KH_1 PF00013.24 EMC82214.1 - 1.1e-39 133.8 12.8 7.1e-16 57.6 0.7 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMC82214.1 - 5.6e-33 112.0 11.0 9.5e-12 44.2 2.5 3.7 3 0 0 3 3 3 3 KH domain ROKNT PF08067.6 EMC82214.1 - 4.9e-23 80.6 9.8 9e-23 79.8 6.8 1.5 1 0 0 1 1 1 1 ROKNT (NUC014) domain KH_2 PF07650.12 EMC82214.1 - 5.4e-13 48.2 8.8 0.0005 19.5 0.0 3.9 3 1 1 4 4 4 3 KH domain KH_4 PF13083.1 EMC82214.1 - 5.5e-07 29.1 4.9 6.2e-06 25.7 0.0 3.2 3 0 0 3 3 3 1 KH domain KH_5 PF13184.1 EMC82214.1 - 0.0092 15.7 5.4 2.5 7.9 0.1 3.8 3 1 1 4 4 4 2 NusA-like KH domain Phi-29_GP3 PF05435.6 EMC82214.1 - 0.021 14.0 0.0 0.045 12.9 0.0 1.5 2 0 0 2 2 2 0 Phi-29 DNA terminal protein GP3 Kinesin PF00225.18 EMC82215.1 - 4.1e-109 364.3 1.6 4.1e-109 364.3 1.1 3.2 4 0 0 4 4 4 1 Kinesin motor domain SKI PF01202.17 EMC82217.1 - 6.1e-08 32.6 0.0 1.6e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase FERM_M PF00373.13 EMC82218.1 - 5.4e-18 65.3 0.2 1.3e-17 64.1 0.0 1.7 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.5 EMC82218.1 - 2.9e-17 62.6 0.4 6e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 EMC82218.1 - 6.1e-17 61.4 0.1 1.8e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.6 EMC82218.1 - 1.4e-16 60.0 3.6 2.6e-16 59.1 2.5 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) Ras PF00071.17 EMC82219.1 - 1.6e-50 170.6 0.1 1.6e-50 170.6 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EMC82219.1 - 1.8e-20 73.6 0.8 4.6e-20 72.2 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC82219.1 - 6.8e-16 57.9 0.0 6.8e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC82219.1 - 2.8e-07 30.4 1.2 6.8e-07 29.2 0.0 2.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC82219.1 - 3.6e-05 23.2 2.2 4e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF3227 PF11537.3 EMC82219.1 - 0.016 15.3 1.9 0.24 11.5 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) Myosin_tail_1 PF01576.14 EMC82219.1 - 0.02 12.6 33.6 0.029 12.1 23.3 1.1 1 0 0 1 1 1 0 Myosin tail AAA_25 PF13481.1 EMC82219.1 - 0.11 11.8 0.2 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMC82219.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.9 3 2 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 EMC82219.1 - 0.39 9.8 3.3 0.46 9.5 1.5 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EMC82219.1 - 3 7.6 36.8 6 6.6 9.3 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 EMC82219.1 - 4.8 7.1 35.5 3.3 7.7 4.6 3.5 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EMC82219.1 - 6.1 6.7 34.9 7.3 6.4 9.3 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LRR_8 PF13855.1 EMC82220.1 - 8.2e-67 220.8 49.8 8.9e-15 54.1 0.7 7.9 3 1 4 7 7 7 7 Leucine rich repeat I-set PF07679.11 EMC82220.1 - 5.1e-49 164.0 0.0 2.2e-19 69.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain LRR_4 PF12799.2 EMC82220.1 - 3.1e-41 138.3 54.0 7.3e-08 31.8 0.6 9.4 4 2 6 10 10 10 10 Leucine Rich repeats (2 copies) Ig_2 PF13895.1 EMC82220.1 - 5.6e-33 112.9 0.0 3.1e-10 40.0 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.1 EMC82220.1 - 6.4e-26 90.5 7.2 7.7e-11 41.8 0.0 4.5 2 1 3 5 5 5 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC82220.1 - 4.4e-24 80.8 39.0 0.039 13.9 0.6 16.3 16 0 0 16 16 16 7 Leucine Rich Repeat Ig_3 PF13927.1 EMC82220.1 - 4.8e-21 75.0 0.0 1e-05 25.9 0.0 4.6 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC82220.1 - 1.6e-17 63.3 0.0 1.2e-06 28.5 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC82220.1 - 1.6e-12 47.3 0.1 0.0096 15.8 0.0 4.1 3 2 0 3 3 3 3 Immunoglobulin V-set domain LRR_9 PF14580.1 EMC82220.1 - 6.9e-11 42.0 14.4 0.0031 17.0 0.2 5.4 1 1 5 6 6 6 3 Leucine-rich repeat C2-set_2 PF08205.7 EMC82220.1 - 1.6e-08 34.3 0.2 0.013 15.4 0.0 4.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain LRR_7 PF13504.1 EMC82220.1 - 3e-07 29.5 39.2 1.8 9.0 0.2 14.2 14 0 0 14 14 14 1 Leucine rich repeat LRR_6 PF13516.1 EMC82220.1 - 4.2e-06 26.2 56.3 0.07 13.2 0.8 14.2 13 3 2 15 15 15 3 Leucine Rich repeat Ribosomal_S27e PF01667.12 EMC82221.1 - 3e-22 77.9 4.5 3.2e-22 77.8 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 Ras PF00071.17 EMC82222.1 - 9.7e-18 64.0 0.1 1e-17 63.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC82222.1 - 2.2e-05 24.9 0.0 2.3e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC82222.1 - 0.0087 15.3 0.0 0.0092 15.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EMC82222.1 - 0.03 14.4 0.0 0.03 14.4 0.0 1.0 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMC82222.1 - 0.035 13.6 0.0 0.035 13.6 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EMC82222.1 - 0.062 12.4 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EMC82222.1 - 0.076 12.2 0.0 0.081 12.1 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit JTB PF05439.7 EMC82223.1 - 3.1e-25 88.1 2.3 3.4e-25 88.0 1.6 1.0 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) bZIP_1 PF00170.16 EMC82224.1 - 5.9e-07 29.3 5.7 5.9e-07 29.3 4.0 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EMC82224.1 - 6.7e-05 22.6 5.1 6.7e-05 22.6 3.5 1.9 1 1 1 2 2 2 2 Basic region leucine zipper Syntaxin_2 PF14523.1 EMC82224.1 - 0.004 17.1 0.3 0.0056 16.6 0.2 1.2 1 0 0 1 1 1 1 Syntaxin-like protein IncA PF04156.9 EMC82224.1 - 0.0053 16.3 1.1 0.0057 16.2 0.7 1.1 1 0 0 1 1 1 1 IncA protein TPR_MLP1_2 PF07926.7 EMC82224.1 - 0.0085 15.8 0.2 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein FlgN PF05130.7 EMC82224.1 - 0.0087 16.3 0.6 0.01 16.0 0.4 1.1 1 0 0 1 1 1 1 FlgN protein GldM_N PF12081.3 EMC82224.1 - 0.035 13.6 0.5 0.045 13.2 0.3 1.0 1 0 0 1 1 1 0 GldM N-terminal domain DUF4570 PF15134.1 EMC82224.1 - 0.037 13.8 3.6 0.049 13.4 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DMPK_coil PF08826.5 EMC82224.1 - 0.05 13.5 2.6 0.069 13.0 1.8 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like APG6 PF04111.7 EMC82224.1 - 0.057 12.4 0.4 0.069 12.1 0.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS5 PF14817.1 EMC82224.1 - 0.058 11.9 1.3 0.065 11.7 0.9 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 FlaC_arch PF05377.6 EMC82224.1 - 0.072 12.9 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EMC82224.1 - 0.08 13.2 0.4 0.1 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Hormone_1 PF00103.15 EMC82224.1 - 0.087 12.1 0.1 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Somatotropin hormone family Filament PF00038.16 EMC82224.1 - 0.087 12.2 2.1 0.11 12.0 1.4 1.0 1 0 0 1 1 1 0 Intermediate filament protein DUF3287 PF11690.3 EMC82224.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF677 PF05055.7 EMC82224.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) HAUS6_N PF14661.1 EMC82224.1 - 0.17 11.1 2.1 0.22 10.8 1.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_Maf PF03131.12 EMC82224.1 - 0.19 12.0 4.2 0.27 11.5 2.9 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor MerR-DNA-bind PF09278.6 EMC82224.1 - 0.2 12.0 2.6 0.35 11.2 1.8 1.5 1 1 0 1 1 1 0 MerR, DNA binding TPX2 PF06886.6 EMC82224.1 - 0.22 11.5 1.8 0.29 11.2 1.2 1.2 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) M PF02370.11 EMC82224.1 - 0.8 10.2 5.0 0.64 10.5 2.0 2.0 1 1 1 2 2 2 0 M protein repeat GAS2 PF02187.12 EMC82227.1 - 5.9e-28 96.4 0.0 1.1e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 EMC82227.1 - 2.5e-06 27.5 0.1 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Hormone_recep PF00104.25 EMC82228.1 - 7.5e-34 116.6 1.0 1.4e-33 115.7 0.7 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC82228.1 - 7.4e-29 99.7 14.7 7.4e-29 99.7 10.2 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) MFS_1 PF07690.11 EMC82229.1 - 8.1e-28 97.1 29.1 1e-15 57.3 0.5 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.20 EMC82230.1 - 1.7e-25 89.6 0.0 3.3e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82230.1 - 7.1e-15 54.7 0.0 4.1e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Strep_67kDa_ant PF06100.6 EMC82230.1 - 0.018 13.4 2.4 0.026 12.8 1.7 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Ank PF00023.25 EMC82231.1 - 6.7e-28 95.0 1.7 3.9e-07 29.5 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EMC82231.1 - 7.1e-28 96.7 0.4 1.2e-22 80.0 0.2 2.9 3 0 0 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC82231.1 - 1.3e-21 76.4 1.1 4.7e-09 36.5 0.1 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC82231.1 - 4.9e-17 60.3 1.0 0.00017 21.4 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC82231.1 - 6.1e-16 58.0 1.4 3.9e-06 26.9 0.2 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Transposase_22 PF02994.9 EMC82231.1 - 0.0064 15.0 1.5 0.0095 14.4 1.1 1.1 1 0 0 1 1 1 1 L1 transposable element Prefoldin_2 PF01920.15 EMC82231.1 - 0.062 13.0 14.7 0.11 12.2 10.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit UPF0565 PF10561.4 EMC82231.1 - 0.83 8.4 1.4 1.6 7.5 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 CENP-F_leu_zip PF10473.4 EMC82231.1 - 0.94 9.3 23.5 0.16 11.7 7.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spectrin PF00435.16 EMC82231.1 - 1.2 9.4 18.9 0.28 11.4 2.2 3.1 1 1 2 3 3 3 0 Spectrin repeat IncA PF04156.9 EMC82231.1 - 2.8 7.5 24.3 7.5 6.0 16.9 1.7 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EMC82231.1 - 2.9 7.8 21.1 6.1 6.8 14.6 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prominin PF05478.6 EMC82231.1 - 8.6 3.7 8.9 13 3.1 6.1 1.2 1 0 0 1 1 1 0 Prominin Xan_ur_permease PF00860.15 EMC82232.1 - 8.3e-90 301.0 25.8 1.1e-89 300.6 17.9 1.1 1 0 0 1 1 1 1 Permease family zf-RING_4 PF14570.1 EMC82233.1 - 6.4e-20 70.4 12.0 1.2e-19 69.6 8.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EMC82233.1 - 4.1e-06 26.5 0.0 8.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC82233.1 - 8.6e-06 25.3 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EMC82233.1 - 1.3e-05 24.7 6.9 2.5e-05 23.8 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EMC82233.1 - 5e-05 23.1 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 EMC82233.1 - 0.028 14.1 5.1 0.074 12.8 3.5 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 EMC82233.1 - 0.029 14.0 9.9 0.062 12.9 6.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC82233.1 - 0.036 14.0 11.3 0.08 12.9 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC82233.1 - 0.25 11.1 8.8 0.48 10.1 6.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF3414 PF11894.3 EMC82234.1 - 0 1668.1 11.3 0 1667.9 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Arf PF00025.16 EMC82235.1 - 1e-75 252.8 0.1 1.1e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC82235.1 - 1.7e-13 50.3 0.0 1.9e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC82235.1 - 1.4e-11 43.9 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC82235.1 - 2.6e-11 42.8 1.1 1.1e-07 30.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMC82235.1 - 3.4e-11 42.7 0.0 4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC82235.1 - 4.9e-09 36.7 0.0 6.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC82235.1 - 7.5e-06 25.8 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC82235.1 - 0.00019 20.9 0.3 0.0022 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMC82235.1 - 0.00076 18.3 0.6 0.035 12.8 0.1 2.6 2 1 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 EMC82235.1 - 0.014 15.7 0.3 0.079 13.2 0.2 1.9 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 EMC82235.1 - 0.023 14.0 0.9 0.17 11.1 0.6 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EMC82235.1 - 0.045 13.2 0.3 1.7 8.1 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EMC82235.1 - 0.051 13.0 0.2 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMC82235.1 - 0.14 12.0 0.1 0.7 9.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain DRIM PF07539.7 EMC82236.1 - 1.1e-48 164.1 0.6 6.2e-48 161.8 0.4 2.4 1 0 0 1 1 1 1 Down-regulated in metastasis Arm PF00514.18 EMC82236.1 - 0.13 12.1 2.3 15 5.5 0.1 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Anoctamin PF04547.7 EMC82237.1 - 2.3e-159 530.8 12.0 2.9e-159 530.5 8.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Syja_N PF02383.13 EMC82238.1 - 1.9e-64 217.4 0.0 2.9e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain WH2 PF02205.15 EMC82239.1 - 1.3e-07 30.9 0.1 2.4e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 WH2 motif WD40 PF00400.27 EMC82240.1 - 5.6e-46 152.8 16.0 6.6e-09 35.3 0.0 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EMC82240.1 - 0.04 12.0 0.4 3.9 5.5 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Methyltransf_22 PF13383.1 EMC82241.1 - 4.6e-15 55.8 0.1 5.5e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EMC82241.1 - 1.5e-05 24.9 0.1 2.6e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain DAO PF01266.19 EMC82242.1 - 3.3e-20 72.3 0.1 3.7e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC82242.1 - 0.0052 17.1 0.3 0.71 10.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMC82242.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 EMC82242.1 - 0.078 11.8 0.0 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EMC82242.1 - 0.091 12.8 0.0 0.31 11.1 0.0 2.0 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EMC82242.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.19 EMC82243.1 - 5.3e-24 84.6 23.4 1.1e-23 83.5 16.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC82243.1 - 1.9e-20 72.9 25.5 1.9e-20 72.9 17.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 EMC82244.1 - 2.4e-52 177.6 0.0 4.1e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82244.1 - 1.1e-20 73.7 0.0 1.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC82244.1 - 0.0035 16.4 0.1 0.012 14.6 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC82244.1 - 0.036 13.7 0.1 0.036 13.7 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF605 PF04652.11 EMC82244.1 - 0.65 9.3 22.6 0.83 8.9 15.6 1.2 1 0 0 1 1 1 0 Vta1 like Stm1_N PF09598.5 EMC82244.1 - 2.3 8.9 11.9 0.53 11.0 5.2 2.1 2 0 0 2 2 2 0 Stm1 DUF4175 PF13779.1 EMC82244.1 - 9.4 3.7 15.7 16 3.0 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAM_decarbox PF01536.11 EMC82245.1 - 2.7e-110 368.1 2.3 3.1e-110 367.9 1.6 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TFIIIC_sub6 PF10419.4 EMC82246.1 - 1.7e-13 49.7 0.0 3.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit Brix PF04427.13 EMC82247.1 - 4e-43 147.3 0.4 6.2e-43 146.6 0.3 1.3 1 0 0 1 1 1 1 Brix domain MFS_1 PF07690.11 EMC82248.1 - 7.3e-34 117.0 42.9 8.9e-20 70.6 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Plasmodium_Vir PF05795.6 EMC82249.1 - 0.0058 15.8 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 1 Plasmodium vivax Vir protein SEFIR PF08357.6 EMC82250.1 - 3.4e-33 114.8 0.2 4.5e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.1 EMC82250.1 - 0.00075 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain Pkinase_Tyr PF07714.12 EMC82252.1 - 3.8e-94 314.5 0.0 4.9e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC82252.1 - 4.6e-51 173.4 0.0 6.4e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC82252.1 - 1.7e-29 101.4 0.2 4.2e-29 100.1 0.2 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC82252.1 - 1.8e-21 75.2 0.4 1e-20 72.8 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC82252.1 - 2.6e-14 52.5 0.4 5.5e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC82252.1 - 8.8e-13 47.5 0.0 3e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.18 EMC82252.1 - 0.0083 15.8 0.0 0.055 13.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family SH3_3 PF08239.6 EMC82252.1 - 0.083 13.0 0.1 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain YcaO PF02624.11 EMC82252.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 YcaO-like family IGFBP PF00219.13 EMC82253.1 - 1.7e-12 47.6 21.9 1.7e-12 47.6 15.2 4.3 4 2 1 5 5 5 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 EMC82253.1 - 6.4e-07 29.3 5.6 6.4e-07 29.3 3.9 3.0 3 0 0 3 3 3 1 Thrombospondin type 1 domain Cys_knot PF00007.17 EMC82253.1 - 2.7e-05 24.1 10.2 2.7e-05 24.1 7.1 3.4 2 1 1 3 3 3 1 Cystine-knot domain VWC PF00093.13 EMC82253.1 - 7.7e-05 22.7 0.3 7.7e-05 22.7 0.2 4.9 4 2 0 4 4 4 1 von Willebrand factor type C domain Laminin_G_2 PF02210.19 EMC82254.1 - 1.2e-105 348.6 0.5 4.7e-25 88.0 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.18 EMC82254.1 - 3.1e-78 260.1 0.0 2e-21 76.3 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_II PF06009.7 EMC82254.1 - 3.8e-33 114.1 3.8 3.8e-33 114.1 2.6 5.5 2 1 3 5 5 5 1 Laminin Domain II Laminin_I PF06008.9 EMC82254.1 - 8.7e-32 110.4 49.3 2.4e-31 109.0 21.4 3.8 2 2 2 4 4 4 2 Laminin Domain I Laminin_EGF PF00053.19 EMC82254.1 - 6.3e-22 77.2 67.9 5.6e-11 42.1 7.2 4.8 4 1 1 5 5 5 3 Laminin EGF-like (Domains III and V) Laminin_G_3 PF13385.1 EMC82254.1 - 7.8e-20 71.6 0.1 1.6e-05 25.2 0.0 5.2 4 1 1 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.2 EMC82254.1 - 0.79 9.9 19.8 2.8 8.2 0.7 5.7 5 0 0 5 5 5 0 Human growth factor-like EGF Sec34 PF04136.10 EMC82254.1 - 3.1 7.4 13.1 0.85 9.3 4.4 3.1 1 1 3 4 4 4 0 Sec34-like family Hist_deacetyl PF00850.14 EMC82256.1 - 1.6e-81 274.0 0.1 2.4e-81 273.4 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Sulfotransfer_1 PF00685.22 EMC82257.1 - 4.6e-35 121.1 0.2 5.9e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 EMC82257.1 - 0.0034 17.1 0.2 0.0053 16.4 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family TPPII PF12580.3 EMC82258.1 - 1.3e-91 305.2 0.0 2.4e-91 304.3 0.0 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.17 EMC82258.1 - 1.2e-73 247.7 0.9 1.7e-73 247.2 0.7 1.2 1 0 0 1 1 1 1 Subtilase family TPPII_N PF12583.3 EMC82258.1 - 0.00058 20.0 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal DUF4399 PF14347.1 EMC82258.1 - 0.063 13.3 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Methyltransf_16 PF10294.4 EMC82259.1 - 2e-32 112.0 0.0 2.7e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMC82259.1 - 3.7e-12 46.2 0.0 5.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC82259.1 - 2.1e-07 31.5 0.0 3.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC82259.1 - 1.3e-06 27.7 0.0 1.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EMC82259.1 - 3.2e-06 27.5 0.0 6.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC82259.1 - 2.9e-05 24.4 0.0 4.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC82259.1 - 0.00059 19.4 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC82259.1 - 0.001 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EMC82259.1 - 0.004 16.5 0.0 0.008 15.5 0.0 1.5 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase Methyltransf_26 PF13659.1 EMC82259.1 - 0.019 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EMC82259.1 - 0.022 13.8 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 EMC82259.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Med31 PF05669.7 EMC82259.1 - 0.04 13.6 0.3 1.8 8.3 0.1 2.9 3 0 0 3 3 3 0 SOH1 TehB PF03848.9 EMC82259.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB Abhydrolase_5 PF12695.2 EMC82260.1 - 3.5e-21 75.4 0.0 4.3e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC82260.1 - 4.8e-08 33.1 0.1 0.001 18.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EMC82260.1 - 0.00039 19.7 0.0 0.0014 17.9 0.0 1.9 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.8 EMC82260.1 - 0.0031 16.9 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF900 PF05990.7 EMC82260.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) XPG_N PF00752.12 EMC82261.1 - 7.3e-32 109.6 0.0 2e-31 108.2 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMC82261.1 - 1.4e-23 82.7 0.0 6.1e-23 80.6 0.0 2.2 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EMC82261.1 - 0.019 15.1 1.8 0.07 13.3 0.0 3.0 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Methyltransf_16 PF10294.4 EMC82262.1 - 2.2e-34 118.3 0.0 2.9e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMC82262.1 - 8.2e-07 28.8 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC82262.1 - 8.2e-05 23.1 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC82262.1 - 0.00092 18.4 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) SBF PF01758.11 EMC82263.1 - 1.8e-48 164.4 18.7 1.8e-48 164.4 13.0 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF2208 PF09973.4 EMC82263.1 - 0.098 11.8 4.9 0.61 9.2 1.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF3278 PF11683.3 EMC82263.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3278) Mem_trans PF03547.13 EMC82263.1 - 5 5.3 20.7 0.041 12.1 5.3 2.9 2 1 0 3 3 3 0 Membrane transport protein Biopterin_H PF00351.16 EMC82265.1 - 3.3e-182 604.6 0.2 4.1e-182 604.3 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EMC82265.1 - 6.2e-05 22.3 0.1 0.00017 20.9 0.0 1.8 2 0 0 2 2 2 1 ACT domain Peptidase_M1 PF01433.15 EMC82266.1 - 6.4e-108 361.3 0.1 8.5e-108 360.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMC82266.1 - 2.7e-44 151.7 1.1 1.4e-43 149.3 0.4 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMC82266.1 - 2.5e-15 56.6 0.1 2.5e-15 56.6 0.1 2.0 3 0 0 3 3 3 1 Peptidase MA superfamily DUF1570 PF07607.6 EMC82266.1 - 0.45 10.5 3.1 2.5 8.0 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1570) EF-hand_7 PF13499.1 EMC82267.1 - 3.8e-08 33.3 0.2 2.9e-06 27.3 0.1 3.4 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC82267.1 - 1.4e-06 27.7 4.2 0.029 14.2 0.2 4.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EMC82267.1 - 0.027 13.8 0.8 0.17 11.2 0.3 2.6 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.27 EMC82267.1 - 0.044 13.0 8.2 0.2 11.0 0.1 4.6 6 0 0 6 6 6 0 EF hand CAP PF00188.21 EMC82268.1 - 5.7e-13 49.4 2.3 1.1e-12 48.5 1.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 EMC82269.1 - 2.1e-19 70.2 3.2 2.9e-19 69.7 2.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 EMC82270.1 - 6.1e-21 75.1 0.8 1.1e-20 74.3 0.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KH_1 PF00013.24 EMC82271.1 - 7.5e-06 25.4 0.2 0.00062 19.3 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EMC82271.1 - 0.00041 19.9 0.0 0.00084 18.9 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EMC82271.1 - 0.0084 15.7 0.0 0.029 14.0 0.0 1.9 1 0 0 1 1 1 1 KH domain RabGAP-TBC PF00566.13 EMC82271.1 - 1.4 8.3 4.7 4.7 6.6 2.1 2.3 2 0 0 2 2 2 0 Rab-GTPase-TBC domain PIN_4 PF13638.1 EMC82272.1 - 0.16 12.0 0.8 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 PIN domain NAP PF00956.13 EMC82273.1 - 4.1e-95 317.5 6.9 4.1e-95 317.5 4.8 1.8 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) Cpn60_TCP1 PF00118.19 EMC82274.1 - 9.8e-09 34.3 0.0 0.00068 18.3 0.0 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Oxysterol_BP PF01237.13 EMC82275.1 - 1.9e-91 306.2 0.2 3e-91 305.5 0.2 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 EMC82275.1 - 7.2e-10 38.9 0.5 3e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 EMC82276.1 - 1.3e-41 140.8 0.6 2.6e-15 56.5 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC82276.1 - 2.4e-39 131.1 2.4 6.8e-10 38.2 0.3 6.5 7 0 0 7 7 7 5 Ankyrin repeat zf-DHHC PF01529.15 EMC82276.1 - 6e-38 129.9 15.2 6e-38 129.9 10.5 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 EMC82276.1 - 9.9e-33 111.9 0.6 3.9e-10 39.9 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC82276.1 - 1.3e-32 108.5 1.4 1.1e-05 25.1 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EMC82276.1 - 1.6e-29 101.2 3.9 6.1e-08 32.6 0.2 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) LIM PF00412.17 EMC82277.1 - 3.2e-30 103.9 28.1 2.9e-17 62.4 4.0 2.1 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.1 EMC82277.1 - 0.024 14.3 9.5 0.055 13.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC4_2 PF13923.1 EMC82277.1 - 0.095 12.7 0.7 0.095 12.7 0.5 4.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) E2F_TDP PF02319.15 EMC82278.1 - 5.2e-45 150.8 1.1 1.8e-21 75.5 0.3 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EMC82278.1 - 0.00017 21.1 0.8 0.0011 18.6 0.0 2.4 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 EMC82278.1 - 0.00046 19.9 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC Cdc6_C PF09079.6 EMC82278.1 - 0.16 11.6 0.1 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 CDC6, C terminal GLTT PF01744.15 EMC82279.1 - 5.9e-06 25.5 15.5 9.8e-05 21.6 2.0 5.9 4 3 2 6 6 6 3 GLTT repeat (6 copies) MrpF_PhaF PF04066.8 EMC82279.1 - 2.1 8.6 7.7 53 4.1 1.8 3.8 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) NACHT PF05729.7 EMC82280.1 - 1.1e-33 116.2 0.0 2.7e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PYRIN PF02758.11 EMC82280.1 - 1.1e-16 60.2 0.0 4.4e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain FISNA PF14484.1 EMC82280.1 - 0.00014 21.7 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 Fish-specific NACHT associated domain AAA_16 PF13191.1 EMC82280.1 - 0.00078 19.4 0.0 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC82280.1 - 0.0083 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMC82280.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMC82280.1 - 0.015 14.3 0.1 0.033 13.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin IBV_3A PF03617.8 EMC82280.1 - 0.025 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 IBV 3A protein AAA_19 PF13245.1 EMC82280.1 - 0.034 13.8 0.1 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 EMC82280.1 - 0.077 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Cyto_ox_2 PF02322.10 EMC82281.1 - 0.088 11.9 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II Alpha_GJ PF03229.8 EMC82281.1 - 0.61 10.4 6.8 0.15 12.4 2.2 1.7 1 1 1 2 2 2 0 Alphavirus glycoprotein J RR_TM4-6 PF06459.7 EMC82281.1 - 1.3 8.8 4.8 1.5 8.6 3.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neisseria_TspB PF05616.8 EMC82281.1 - 6.4 5.0 9.0 9.1 4.5 6.3 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DJ-1_PfpI PF01965.19 EMC82282.1 - 5.1e-09 35.7 0.0 6.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family PTB PF08416.8 EMC82283.1 - 1e-46 158.0 3.4 2e-46 157.1 2.3 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.23 EMC82283.1 - 1.8e-10 40.0 0.1 4.8e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC82283.1 - 7.1e-09 35.1 0.0 1.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.18 EMC82283.1 - 3.3e-06 27.1 2.1 6.5e-06 26.1 0.3 2.2 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.12 EMC82283.1 - 7.8e-06 25.2 0.0 1.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC82283.1 - 0.037 14.2 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Transmemb_17 PF09799.4 EMC82284.1 - 1.3e-28 99.4 9.3 1.5e-28 99.2 6.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein SAND PF01342.16 EMC82285.1 - 5.1e-26 90.1 0.1 1.4e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.13 EMC82285.1 - 1.3e-10 40.9 15.8 1.3e-10 40.9 10.9 2.0 2 0 0 2 2 2 1 MYND finger 7tm_1 PF00001.16 EMC82286.1 - 2.2e-71 240.0 5.0 2.5e-71 239.8 3.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82286.1 - 1.2e-11 44.3 8.1 3e-05 23.3 3.9 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC82286.1 - 0.0078 15.3 10.4 0.014 14.4 4.0 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Hormone_2 PF00123.15 EMC82287.1 - 5.7e-21 74.0 0.1 2.5e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 Peptide hormone PP1_inhibitor PF05361.7 EMC82287.1 - 0.012 15.2 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Cadherin PF00028.12 EMC82288.1 - 2.6e-21 75.6 6.5 8.3e-10 38.7 0.1 4.7 4 1 0 4 4 4 3 Cadherin domain DUF3298 PF11738.3 EMC82288.1 - 0.097 13.1 0.6 0.41 11.1 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3298) Mad3_BUB1_I PF08311.7 EMC82289.1 - 1e-47 161.0 0.3 1e-47 161.0 0.2 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 MerR-DNA-bind PF09278.6 EMC82289.1 - 0.00077 19.8 3.6 0.0042 17.4 2.5 2.3 1 0 0 1 1 1 1 MerR, DNA binding Pkinase PF00069.20 EMC82289.1 - 0.0025 16.9 0.0 0.0025 16.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain TPR_14 PF13428.1 EMC82289.1 - 0.094 13.3 0.4 0.59 10.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Matrilin_ccoil PF10393.4 EMC82289.1 - 0.12 11.7 6.3 0.38 10.1 4.4 1.9 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Pkinase PF00069.20 EMC82290.1 - 1.3e-67 227.7 0.0 1.7e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82290.1 - 7.3e-45 153.0 0.0 1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMC82290.1 - 1.2e-13 51.2 1.0 3.2e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EMC82290.1 - 1.1e-06 27.7 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC82290.1 - 0.11 12.1 0.3 6.7 6.3 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family PI-PLC-X PF00388.14 EMC82291.1 - 1.2e-66 222.5 0.2 6.1e-66 220.3 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PLC-beta_C PF08703.5 EMC82291.1 - 9.2e-46 155.9 31.6 9.2e-46 155.9 21.9 2.4 2 0 0 2 2 2 1 PLC-beta C terminal PI-PLC-Y PF00387.14 EMC82291.1 - 1.3e-43 147.7 2.1 1.3e-43 147.7 1.5 2.3 2 1 1 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC82291.1 - 3.1e-22 78.3 0.0 1.1e-21 76.5 0.0 2.1 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EMC82291.1 - 1.2e-06 28.1 0.0 3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF1154 PF06631.6 EMC82291.1 - 0.0022 17.6 6.6 0.0022 17.6 4.6 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1154) DUF4594 PF15266.1 EMC82293.1 - 0.00016 21.8 0.1 0.00016 21.8 0.1 3.1 2 1 2 4 4 4 1 Domain of unknown function (DUF4594) Patched PF02460.13 EMC82294.1 - 1.4e-05 23.2 25.5 2.2e-05 22.6 3.3 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EMC82294.1 - 3.6 7.0 28.2 0.059 12.8 9.8 2.8 2 1 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation TPR_MLP1_2 PF07926.7 EMC82296.1 - 0.016 14.9 2.2 0.016 14.9 1.5 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EMC82296.1 - 0.72 9.6 15.5 0.25 11.0 0.6 4.0 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF745 PF05335.8 EMC82296.1 - 1.3 8.5 13.7 1.2 8.6 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF745) TnpV PF14198.1 EMC82296.1 - 3.3 7.6 13.8 1.4 8.8 3.9 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Spc7 PF08317.6 EMC82296.1 - 4.2 5.9 20.2 6.3 5.3 14.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EMC82296.1 - 7.4 7.0 10.5 10 6.6 0.4 2.6 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Acyl-CoA_dh_1 PF00441.19 EMC82297.1 - 7.8e-39 133.1 0.1 1.2e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC82297.1 - 3.3e-32 111.3 0.0 5.7e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMC82297.1 - 1.8e-18 65.7 0.0 3.2e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMC82297.1 - 1.4e-10 41.5 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EMC82297.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal BAH PF01426.13 EMC82298.1 - 1.5e-14 53.7 0.1 4.3e-14 52.2 0.1 1.7 1 1 0 1 1 1 1 BAH domain DUF4437 PF14499.1 EMC82298.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Sulfotransfer_2 PF03567.9 EMC82299.1 - 0.032 13.9 0.0 0.034 13.8 0.0 1.0 1 0 0 1 1 1 0 Sulfotransferase family Intron_maturas2 PF01348.16 EMC82299.1 - 0.055 13.4 0.1 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Type II intron maturase 7tm_1 PF00001.16 EMC82300.1 - 2.1e-48 164.6 24.9 2.5e-48 164.4 17.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82300.1 - 2.5e-13 49.8 23.7 2.9e-13 49.5 16.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CCDC32 PF14989.1 EMC82301.1 - 1e-34 119.4 0.0 1.2e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing 32 PCMT PF01135.14 EMC82302.1 - 5.3e-34 117.5 0.0 5.3e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EMC82302.1 - 3.9e-06 26.5 0.0 5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC82302.1 - 0.0001 22.8 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EMC82302.1 - 0.0012 18.4 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.1 EMC82302.1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMC82302.1 - 0.017 15.6 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMC82302.1 - 0.02 14.2 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EMC82302.1 - 0.022 13.8 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EMC82302.1 - 0.029 13.4 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EMC82302.1 - 0.029 14.0 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EMC82302.1 - 0.049 13.6 0.0 0.098 12.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EMC82302.1 - 0.076 12.0 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EMC82302.1 - 0.077 12.0 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 EMC82302.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_3 PF01596.12 EMC82302.1 - 0.096 11.7 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase TSLP PF15216.1 EMC82303.1 - 0.099 12.3 0.5 0.42 10.3 0.1 2.2 2 0 0 2 2 2 0 Thymic stromal lymphopoietin Rad51 PF08423.6 EMC82304.1 - 2.4e-142 472.3 0.1 2.9e-142 472.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMC82304.1 - 2.5e-14 53.1 0.0 3.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EMC82304.1 - 1.1e-12 47.9 2.1 1.3e-12 47.6 0.5 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 EMC82304.1 - 2.6e-08 33.3 0.1 3.9e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EMC82304.1 - 5.9e-06 25.5 0.7 2.8e-05 23.3 0.5 2.1 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 EMC82304.1 - 0.00067 19.8 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH PF00633.18 EMC82304.1 - 0.0065 16.1 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 EMC82304.1 - 0.018 15.3 0.0 0.1 12.8 0.0 2.1 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein TPR_11 PF13414.1 EMC82305.1 - 5.8e-05 22.6 0.6 0.44 10.2 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 EMC82305.1 - 0.00031 20.6 1.3 0.0056 16.7 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC82305.1 - 0.0048 17.5 7.5 1 10.0 0.0 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC82305.1 - 0.095 12.5 1.2 1.7 8.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC82305.1 - 9.2 6.4 8.2 74 3.6 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat GFRP PF06399.8 EMC82306.1 - 1.9e-38 129.9 0.0 2.1e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) BORG_CEP PF14957.1 EMC82307.1 - 1.8e-08 35.2 0.1 4.1e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Cdc42 effector Viral_P18 PF04521.8 EMC82308.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DHODB_Fe-S_bind PF10418.4 EMC82308.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ribosomal_L21p PF00829.16 EMC82309.1 - 4.1e-23 81.3 0.2 8.1e-23 80.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein C2 PF00168.25 EMC82310.1 - 8.4e-24 83.2 0.0 2.3e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain Anoctamin PF04547.7 EMC82312.1 - 9.2e-73 245.4 1.5 8.6e-54 182.8 0.4 2.1 2 0 0 2 2 2 2 Calcium-activated chloride channel TIR PF01582.15 EMC82313.1 - 9.8e-17 60.7 0.0 1.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.1 EMC82313.1 - 1.3e-09 38.0 0.0 2.9e-08 33.7 0.0 2.3 1 1 1 2 2 2 1 TIR domain Ig_2 PF13895.1 EMC82313.1 - 0.0008 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Arm PF00514.18 EMC82314.1 - 1.8e-20 71.9 0.2 2.9e-06 26.8 0.0 5.6 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC82314.1 - 0.0004 20.6 0.1 0.0032 17.7 0.0 2.5 2 1 0 2 2 2 1 HEAT repeats Proteasom_PSMB PF10508.4 EMC82314.1 - 0.024 12.9 0.1 0.052 11.8 0.0 1.5 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT PF02985.17 EMC82314.1 - 0.044 13.8 0.0 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat DUF383 PF04063.9 EMC82314.1 - 0.11 12.0 0.1 15 5.0 0.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF383) Adaptin_N PF01602.15 EMC82314.1 - 0.18 10.0 0.1 0.44 8.8 0.0 1.6 2 0 0 2 2 2 0 Adaptin N terminal region Dispanin PF04505.7 EMC82315.1 - 3.3e-06 26.5 0.0 5.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein YwiC PF14256.1 EMC82315.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.4 2 0 0 2 2 2 0 YwiC-like protein Glyco_hydro_65m PF03632.10 EMC82317.1 - 5e-85 285.3 0.0 1.3e-83 280.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain COX8 PF02285.10 EMC82318.1 - 8.8e-11 41.1 0.4 9.6e-11 41.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIII Ric8 PF10165.4 EMC82319.1 - 7.5e-152 506.2 6.2 2.6e-122 408.8 0.9 2.7 2 1 1 3 3 3 2 Guanine nucleotide exchange factor synembryn Occludin_ELL PF07303.8 EMC82319.1 - 0.003 18.2 1.6 0.22 12.2 0.1 3.2 3 0 0 3 3 3 1 Occludin homology domain AnfG_VnfG PF03139.10 EMC82320.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Uteroglobin PF01099.12 EMC82321.1 - 1.5e-06 27.8 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Uteroglobin family CesT PF05932.8 EMC82321.1 - 0.1 12.4 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family HEAT_EZ PF13513.1 EMC82321.1 - 1.8 9.1 4.2 3.1 8.4 0.1 2.4 2 1 1 3 3 3 0 HEAT-like repeat SieB PF14163.1 EMC82322.1 - 0.0098 15.4 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Superinfection exclusion protein B LRRCT PF01463.19 EMC82322.1 - 0.01 16.0 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain 7tm_1 PF00001.16 EMC82323.1 - 4.1e-54 183.4 13.9 2.5e-34 118.5 4.3 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC82323.1 - 0.016 14.3 0.8 0.032 13.3 0.5 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 EMC82323.1 - 0.019 14.0 1.1 0.019 14.0 0.8 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv FA_desaturase PF00487.19 EMC82323.1 - 1.2 8.5 23.6 0.2 11.0 5.9 2.8 1 1 2 3 3 3 0 Fatty acid desaturase Tankyrase_bdg_C PF15327.1 EMC82324.1 - 2.2e-33 115.9 6.7 2.9e-33 115.5 4.6 1.2 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain SSrecog PF03531.9 EMC82325.1 - 4.4e-103 343.3 0.0 7.1e-103 342.7 0.0 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EMC82325.1 - 1.8e-29 101.5 0.1 1.2e-27 95.7 0.1 2.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box PF00505.14 EMC82325.1 - 4.8e-24 84.4 5.0 4.8e-24 84.4 3.5 2.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC82325.1 - 1.7e-13 50.7 5.1 1.7e-13 50.7 3.5 2.6 2 0 0 2 2 2 1 HMG-box domain KTSC PF13619.1 EMC82325.1 - 0.0088 15.6 0.2 3.7 7.2 0.0 2.7 2 0 0 2 2 2 2 KTSC domain P2X_receptor PF00864.14 EMC82326.1 - 2e-68 230.8 0.1 5.3e-51 173.4 0.0 2.0 2 0 0 2 2 2 2 ATP P2X receptor MFS_1 PF07690.11 EMC82327.1 - 0.0011 17.7 36.0 0.002 16.9 12.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.1 EMC82328.1 - 2.3e-36 123.3 12.5 2.4e-15 56.0 0.1 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC82328.1 - 3.9e-19 67.8 9.3 3.4e-05 23.3 0.1 4.1 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC82328.1 - 4.4e-14 50.3 10.8 0.26 11.4 0.0 6.5 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC82328.1 - 9e-09 34.1 14.6 0.85 10.0 0.1 7.1 7 0 0 7 7 7 3 Leucine rich repeat LRR_9 PF14580.1 EMC82328.1 - 4.8e-08 32.7 0.5 0.00043 19.9 0.1 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.1 EMC82328.1 - 4.3e-06 26.4 0.0 5.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC82328.1 - 0.0002 21.0 4.9 14 6.1 0.0 5.7 5 1 1 6 6 6 2 Leucine Rich repeat zf-Tim10_DDP PF02953.10 EMC82329.1 - 2.6e-19 68.2 0.5 3.9e-19 67.7 0.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger UQ_con PF00179.21 EMC82330.1 - 1.4e-22 79.6 0.0 1.6e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC82330.1 - 0.0017 18.0 0.1 0.0024 17.6 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-DHHC PF01529.15 EMC82332.1 - 4.7e-16 58.6 5.8 1.8e-13 50.2 2.7 2.9 2 1 1 3 3 3 2 DHHC palmitoyltransferase Thioredoxin PF00085.15 EMC82333.1 - 3.1e-11 42.8 0.0 5.6e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC82333.1 - 0.05 13.7 0.1 0.18 11.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Viral_P18 PF04521.8 EMC82334.1 - 0.4 10.1 6.6 0.53 9.7 4.6 1.4 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein APG6 PF04111.7 EMC82334.1 - 1 8.3 15.3 1.1 8.2 10.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.7 EMC82334.1 - 1.2 8.9 5.7 1.3 8.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0449 PF15136.1 EMC82334.1 - 1.4 9.1 13.8 0.72 10.0 6.3 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Syntaxin PF00804.20 EMC82334.1 - 1.9 8.7 11.0 2.4 8.3 7.6 1.1 1 0 0 1 1 1 0 Syntaxin ARGLU PF15346.1 EMC82334.1 - 2.4 7.8 22.9 2.8 7.7 15.8 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 MHC_II_beta PF00969.14 EMC82334.1 - 3.3 7.7 5.1 5.4 7.0 0.1 2.4 1 1 1 2 2 2 0 Class II histocompatibility antigen, beta domain Cgr1 PF03879.9 EMC82334.1 - 5 7.3 16.5 6.5 6.9 10.6 1.7 1 1 1 2 2 2 0 Cgr1 family DUF3552 PF12072.3 EMC82334.1 - 8 5.6 18.8 20 4.2 13.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) SRCR PF00530.13 EMC82335.1 - 2.6e-26 91.8 4.9 3.7e-26 91.3 3.4 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC82335.1 - 0.00019 21.5 2.0 0.00029 21.0 1.4 1.4 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF3357 PF11837.3 EMC82335.1 - 0.022 14.5 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) UbiA PF01040.13 EMC82335.1 - 0.041 13.0 0.4 0.054 12.7 0.3 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family CTP_synth_N PF06418.9 EMC82336.1 - 4.8e-104 347.3 0.1 8.3e-104 346.5 0.1 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EMC82336.1 - 9.1e-55 185.0 0.0 1.4e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMC82336.1 - 8.4e-11 41.7 0.0 1.9e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EMC82336.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain EF-hand_1 PF00036.27 EMC82337.1 - 2.5e-07 29.5 0.6 2.5e-07 29.5 0.4 2.1 2 0 0 2 2 2 1 EF hand S_100 PF01023.14 EMC82337.1 - 1.4e-06 27.4 0.7 2.6e-06 26.6 0.5 1.5 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 EMC82337.1 - 1.1e-05 25.5 0.7 2.3e-05 24.4 0.2 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC82337.1 - 2.6e-05 23.7 0.2 8.3e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC82337.1 - 7.9e-05 22.2 1.1 0.00017 21.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EMC82337.1 - 0.00012 21.2 0.4 0.00012 21.2 0.2 1.8 2 0 0 2 2 2 1 EF hand Toprim_2 PF13155.1 EMC82337.1 - 0.00022 21.5 0.1 0.00071 19.8 0.0 1.8 2 1 0 2 2 2 1 Toprim-like EF-hand_4 PF12763.2 EMC82337.1 - 0.0048 16.6 0.1 0.0084 15.8 0.1 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3381 PF11861.3 EMC82337.1 - 0.04 13.4 0.1 0.09 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Taxilin PF09728.4 EMC82338.1 - 5.7e-116 386.9 73.0 5.7e-116 386.9 50.6 2.4 3 0 0 3 3 3 1 Myosin-like coiled-coil protein WD40 PF00400.27 EMC82339.1 - 1.1e-37 126.5 12.4 6.2e-09 35.4 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMC82339.1 - 5.4e-30 103.1 0.5 1.5e-29 101.6 0.4 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EMC82339.1 - 2.9e-05 23.8 0.2 0.016 14.9 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.7 EMC82339.1 - 0.043 12.8 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein BEN PF10523.4 EMC82340.1 - 9.9e-28 96.0 0.2 1.9e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 BEN domain DUF1647 PF07801.6 EMC82340.1 - 0.076 12.5 0.0 7.3 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) TPR_7 PF13176.1 EMC82342.1 - 0.045 13.5 0.0 50 4.0 0.0 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat Collagen PF01391.13 EMC82343.1 - 5.1e-16 57.9 59.9 2.8e-09 36.3 17.5 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TIG PF01833.19 EMC82345.1 - 4e-13 49.1 4.4 5.6e-13 48.6 0.1 2.5 2 0 0 2 2 2 1 IPT/TIG domain Lactamase_B PF00753.22 EMC82346.1 - 8.9e-17 61.3 8.6 2.2e-16 60.1 5.9 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC82346.1 - 0.00061 19.3 0.2 0.0023 17.5 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TNFR_c6 PF00020.13 EMC82348.1 - 3.2e-08 33.5 40.0 3.4e-05 23.8 7.7 4.8 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region UPF0118 PF01594.11 EMC82348.1 - 0.0034 16.4 0.1 0.0043 16.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF20 Tetraspannin PF00335.15 EMC82348.1 - 0.019 14.2 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 0 Tetraspanin family Claudin_2 PF13903.1 EMC82348.1 - 0.021 14.5 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TMEM154 PF15102.1 EMC82348.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF948 PF06103.6 EMC82348.1 - 0.088 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4366 PF14283.1 EMC82348.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CcoS PF03597.10 EMC82348.1 - 1.3 8.5 4.2 1.8 8.0 2.9 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type SecE PF00584.15 EMC82348.1 - 4.3 6.9 6.3 22 4.7 0.0 2.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex LRR_8 PF13855.1 EMC82350.1 - 8.6e-37 124.7 53.0 1.1e-06 28.2 0.2 9.5 4 2 6 11 11 11 11 Leucine rich repeat LRR_4 PF12799.2 EMC82350.1 - 1.3e-35 120.4 50.9 6.8e-05 22.3 1.6 12.2 4 4 8 14 14 14 13 Leucine Rich repeats (2 copies) PP2C PF00481.16 EMC82350.1 - 5.5e-34 117.7 0.0 9.1e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EMC82350.1 - 3.4e-25 84.1 56.0 0.15 12.2 0.4 20.0 18 1 2 20 20 20 12 Leucine Rich Repeat LRR_7 PF13504.1 EMC82350.1 - 2.3e-07 29.8 59.1 1.4 9.4 0.3 17.5 20 0 0 20 20 20 3 Leucine rich repeat LRR_6 PF13516.1 EMC82350.1 - 2.3e-05 24.0 37.8 0.08 13.0 1.2 14.2 15 2 1 16 16 16 3 Leucine Rich repeat MARVEL PF01284.18 EMC82351.1 - 0.12 12.1 2.8 0.19 11.5 1.9 1.4 1 0 0 1 1 1 0 Membrane-associating domain adh_short PF00106.20 EMC82352.1 - 3.1e-30 105.3 0.0 4e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC82352.1 - 2e-13 50.4 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC82352.1 - 1.3e-11 44.7 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMC82352.1 - 0.0076 16.2 0.0 0.11 12.4 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMC82352.1 - 0.052 12.6 0.0 0.097 11.7 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMC82352.1 - 0.088 12.2 0.2 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AAA PF00004.24 EMC82353.1 - 4e-42 143.5 0.0 9.8e-42 142.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMC82353.1 - 9.3e-30 102.3 0.1 3.9e-29 100.3 0.1 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EMC82353.1 - 1.5e-22 79.2 6.6 4.1e-22 77.8 4.2 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EMC82353.1 - 1.6e-06 28.3 0.1 0.01 15.9 0.0 2.9 2 1 1 3 3 2 2 AAA domain AAA_17 PF13207.1 EMC82353.1 - 7.8e-06 26.7 0.0 2.6e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMC82353.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EMC82353.1 - 1.5e-05 23.8 0.0 2.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EMC82353.1 - 1.6e-05 24.3 0.2 0.15 11.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EMC82353.1 - 2.7e-05 23.3 0.0 5.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMC82353.1 - 2.8e-05 24.0 0.0 7.5e-05 22.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMC82353.1 - 4e-05 23.3 0.0 0.00012 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC82353.1 - 0.00018 21.5 0.0 0.0035 17.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EMC82353.1 - 0.00038 20.4 0.0 0.0024 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EMC82353.1 - 0.00044 20.1 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMC82353.1 - 0.00052 19.0 0.0 0.0011 17.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 EMC82353.1 - 0.0016 18.7 0.0 0.0063 16.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EMC82353.1 - 0.0023 18.0 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 1 RNA helicase PhoH PF02562.11 EMC82353.1 - 0.0035 16.5 0.0 0.011 15.0 0.0 1.8 1 1 0 1 1 1 1 PhoH-like protein KaiC PF06745.8 EMC82353.1 - 0.005 15.9 0.1 0.8 8.7 0.0 2.3 1 1 1 2 2 2 1 KaiC ResIII PF04851.10 EMC82353.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EMC82353.1 - 0.012 15.2 0.0 0.28 10.8 0.0 2.4 2 1 1 3 3 2 0 NACHT domain Mg_chelatase PF01078.16 EMC82353.1 - 0.026 13.6 0.0 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EMC82353.1 - 0.029 13.4 0.0 0.19 10.8 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EMC82353.1 - 0.037 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EMC82353.1 - 0.045 13.4 0.4 1.1 8.8 0.0 2.4 2 1 1 3 3 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EMC82353.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EMC82353.1 - 0.059 12.8 0.0 0.26 10.7 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EMC82353.1 - 0.092 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EMC82353.1 - 0.097 12.1 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase MCM PF00493.18 EMC82353.1 - 0.1 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_24 PF13479.1 EMC82353.1 - 0.11 12.0 0.1 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMC82353.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_21 PF13304.1 EMC82353.1 - 0.3 11.0 2.3 9.1 6.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain AATF-Che1 PF13339.1 EMC82353.1 - 0.31 11.1 3.6 0.22 11.6 1.1 1.9 2 0 0 2 2 1 0 Apoptosis antagonizing transcription factor USP8_dimer PF08969.6 EMC82353.1 - 0.88 9.5 4.8 2 8.4 3.3 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain EF-1_beta_acid PF10587.4 EMC82353.1 - 3.2 7.9 13.4 4.4 7.5 0.3 3.6 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Serpin PF00079.15 EMC82354.1 - 7e-102 341.3 7.2 7.8e-102 341.1 5.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC82355.1 - 1.4e-124 415.9 1.5 1.7e-124 415.7 1.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PC_rep PF01851.17 EMC82355.1 - 0.097 12.9 0.0 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Serpin PF00079.15 EMC82356.1 - 2.4e-127 425.1 0.1 2.7e-127 424.9 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC82357.1 - 4.2e-125 417.7 0.6 4.8e-125 417.5 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC82358.1 - 1.4e-125 419.3 1.9 1.6e-125 419.1 1.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2847 PF11009.3 EMC82358.1 - 0.014 14.9 0.3 0.065 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Acetyltransf_8 PF13523.1 EMC82358.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Serpin PF00079.15 EMC82359.1 - 3.2e-119 398.3 0.7 3.6e-119 398.2 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RRF PF01765.14 EMC82359.1 - 0.013 15.0 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 Ribosome recycling factor Serpin PF00079.15 EMC82360.1 - 3e-135 451.1 1.9 3.4e-135 450.9 1.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC82361.1 - 5.5e-127 423.9 3.3 6.2e-127 423.7 2.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC82362.1 - 5.9e-130 433.6 5.1 6.8e-130 433.5 3.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC82363.1 - 1.3e-135 452.2 0.8 1.5e-135 452.1 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FbpA PF05833.6 EMC82363.1 - 0.0023 16.5 1.1 0.0034 15.9 0.8 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Serpin PF00079.15 EMC82364.1 - 9.4e-27 94.1 0.0 1.1e-26 93.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC82365.1 - 5.5e-29 101.4 0.1 5.8e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Med25 PF11232.3 EMC82365.1 - 0.078 12.6 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 7tm_1 PF00001.16 EMC82366.1 - 2.8e-27 95.4 3.3 4.3e-27 94.8 2.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC82366.1 - 2.4e-12 46.8 4.6 2.4e-12 46.8 3.2 2.2 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 EMC82366.1 - 7.7e-06 25.2 6.4 1e-05 24.8 4.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Antimicrobial10 PF08105.6 EMC82366.1 - 0.055 13.0 0.3 0.15 11.7 0.1 1.8 1 1 0 1 1 1 0 Metchnikowin family 7TM_GPCR_Srx PF10328.4 EMC82366.1 - 0.067 12.2 6.6 0.089 11.8 4.6 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Ndc80_HEC PF03801.8 EMC82367.1 - 1e-49 168.0 0.0 3e-49 166.5 0.0 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family LPP PF04728.8 EMC82367.1 - 0.011 15.4 0.0 0.054 13.2 0.0 2.3 1 1 0 1 1 1 0 Lipoprotein leucine-zipper PRAP PF15314.1 EMC82367.1 - 0.02 15.1 0.9 0.071 13.4 0.6 1.9 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine Cluap1 PF10234.4 EMC82367.1 - 0.23 10.6 0.0 0.23 10.6 0.0 4.5 3 1 1 4 4 4 0 Clusterin-associated protein-1 Reo_sigmaC PF04582.7 EMC82367.1 - 0.44 9.6 6.6 0.11 11.6 0.2 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF4407 PF14362.1 EMC82367.1 - 1.5 7.7 23.7 0.025 13.5 3.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) HrpB7 PF09486.5 EMC82367.1 - 3.2 7.6 20.3 0.47 10.3 0.4 4.0 2 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.7 EMC82367.1 - 9.9 5.9 45.6 0.53 10.0 7.3 4.7 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein HATPase_c_3 PF13589.1 EMC82368.1 - 6.5e-15 54.9 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC82368.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EMI PF07546.8 EMC82369.1 - 3.7e-21 75.3 8.8 3.7e-21 75.3 6.1 2.5 3 0 0 3 3 1 1 EMI domain C1q PF00386.16 EMC82369.1 - 7.1e-16 58.3 0.8 3.1e-15 56.2 0.1 2.4 2 1 0 2 2 2 1 C1q domain Reo_sigmaC PF04582.7 EMC82369.1 - 3.5e-06 26.4 8.1 0.012 14.8 0.4 4.2 2 2 2 4 4 4 2 Reovirus sigma C capsid protein DUF1664 PF07889.7 EMC82369.1 - 5.1e-06 26.2 24.0 0.028 14.2 0.0 6.5 4 2 3 7 7 6 4 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EMC82369.1 - 2.2e-05 24.5 13.7 0.0047 17.1 0.0 6.5 6 1 0 6 6 5 1 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.13 EMC82369.1 - 4.2e-05 23.1 5.1 1.4 8.3 0.0 5.0 3 2 0 3 3 3 2 Apolipoprotein A1/A4/E domain Sec34 PF04136.10 EMC82369.1 - 0.032 13.9 0.1 0.032 13.9 0.0 4.1 3 2 2 5 5 5 0 Sec34-like family Spc7 PF08317.6 EMC82369.1 - 0.035 12.7 27.1 0.055 12.1 0.1 4.7 3 1 3 6 6 6 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 EMC82369.1 - 0.063 13.4 23.2 1.4 9.0 0.0 5.9 5 2 1 6 6 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 EMC82369.1 - 0.072 12.6 0.3 0.31 10.5 0.1 2.2 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec8_exocyst PF04048.9 EMC82369.1 - 0.1 12.1 0.1 0.1 12.1 0.1 5.0 5 2 2 7 7 7 0 Sec8 exocyst complex component specific domain IncA PF04156.9 EMC82369.1 - 0.11 12.0 0.0 0.11 12.0 0.0 5.3 2 2 1 4 4 4 0 IncA protein WEMBL PF05701.6 EMC82369.1 - 0.69 8.3 22.6 1.9 6.8 4.2 4.1 3 1 1 4 4 4 0 Weak chloroplast movement under blue light HrpB7 PF09486.5 EMC82369.1 - 0.8 9.6 5.0 4.4 7.2 0.0 3.7 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF948 PF06103.6 EMC82369.1 - 1.6 8.6 12.3 1.9 8.3 0.0 5.4 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF948) Collagen PF01391.13 EMC82369.1 - 6 6.5 5.4 4.5 6.8 1.9 2.0 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Spectrin PF00435.16 EMC82369.1 - 9.7 6.5 16.9 6.8 7.0 0.7 5.5 2 2 4 6 6 6 0 Spectrin repeat LNS2 PF08235.8 EMC82370.1 - 2.3e-69 231.9 0.0 3.4e-69 231.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EMC82370.1 - 9.2e-51 170.1 0.1 2.2e-50 168.9 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 EMC82370.1 - 7.9e-05 22.4 0.3 7.9e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Tash_PEST PF07708.6 EMC82370.1 - 0.027 14.3 2.9 0.14 12.1 2.0 2.4 1 0 0 1 1 1 0 Tash protein PEST motif Hydrolase_3 PF08282.7 EMC82370.1 - 1.4 8.4 0.0 1.4 8.4 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase fn3 PF00041.16 EMC82371.1 - 2.1e-78 258.5 0.1 1.2e-15 57.4 0.0 5.9 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 EMC82371.1 - 3.6e-74 244.6 13.4 1.7e-21 75.8 0.0 7.8 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82371.1 - 2.4e-39 133.2 1.8 2.6e-09 37.0 0.1 7.1 8 0 0 8 8 8 5 Immunoglobulin domain Ig_3 PF13927.1 EMC82371.1 - 5e-21 74.9 6.3 0.00028 21.3 0.1 7.1 6 1 0 6 6 6 4 Immunoglobulin domain V-set PF07686.12 EMC82371.1 - 1e-18 67.3 17.7 0.00022 21.1 0.4 9.0 7 4 0 7 7 7 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC82371.1 - 2.3e-12 46.6 0.9 0.00046 20.0 0.0 4.6 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC82371.1 - 2.5e-11 43.5 13.6 0.05 13.7 0.0 7.2 7 1 0 7 7 7 4 Immunoglobulin domain Herpes_gE PF02480.11 EMC82371.1 - 0.0023 16.2 1.5 0.078 11.2 0.0 3.6 4 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E Tissue_fac PF01108.12 EMC82371.1 - 0.0023 17.6 0.0 1.5 8.6 0.0 4.0 4 0 0 4 4 4 1 Tissue factor Herpes_gI PF01688.12 EMC82371.1 - 0.0055 15.8 0.1 7 5.7 0.0 3.7 4 0 0 4 4 4 1 Alphaherpesvirus glycoprotein I DDA1 PF10172.4 EMC82371.1 - 0.29 10.9 2.1 0.45 10.3 0.3 2.1 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase EF-hand_1 PF00036.27 EMC82372.1 - 3.9e-14 50.7 12.9 5.2e-08 31.6 1.1 4.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 EMC82372.1 - 2.8e-12 46.5 8.0 5e-07 29.7 0.6 3.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EMC82372.1 - 8.1e-12 43.9 7.4 6.6e-08 31.8 0.6 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EMC82372.1 - 1.5e-11 43.7 8.0 4.3e-05 23.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC82372.1 - 4.3e-06 25.8 2.9 1.4e-05 24.1 0.9 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 EMC82372.1 - 0.00054 19.5 0.0 0.88 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 EMC82372.1 - 0.0033 17.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF1880 PF08976.6 EMC82372.1 - 0.041 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF2267 PF10025.4 EMC82372.1 - 0.075 13.0 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SPARC_Ca_bdg PF10591.4 EMC82372.1 - 0.078 13.0 0.8 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 EMC82373.1 - 3.9e-14 50.7 12.9 5.2e-08 31.6 1.1 4.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 EMC82373.1 - 2.5e-12 46.7 7.8 4.7e-07 29.8 0.6 3.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EMC82373.1 - 8e-12 43.9 7.4 6.6e-08 31.8 0.6 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EMC82373.1 - 1.5e-11 43.7 8.0 4.3e-05 23.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC82373.1 - 4.2e-06 25.8 2.9 1.4e-05 24.1 0.9 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 EMC82373.1 - 0.00051 19.6 0.0 0.88 9.2 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 EMC82373.1 - 0.0034 17.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF1880 PF08976.6 EMC82373.1 - 0.042 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF2267 PF10025.4 EMC82373.1 - 0.08 13.0 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SPARC_Ca_bdg PF10591.4 EMC82373.1 - 0.087 12.8 1.1 0.16 12.0 0.3 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Homeobox_KN PF05920.6 EMC82374.1 - 6.8e-16 57.6 1.0 1.2e-15 56.8 0.7 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC82374.1 - 1.2e-07 31.2 1.2 2e-07 30.5 0.8 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC82374.1 - 0.1 11.6 0.2 0.22 10.6 0.2 1.5 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Myc_N PF01056.13 EMC82375.1 - 1.9e-46 158.7 7.5 2.7e-46 158.2 5.2 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Myc-LZ PF02344.10 EMC82375.1 - 8.4e-21 73.2 11.8 8.4e-21 73.2 8.2 2.3 2 0 0 2 2 2 1 Myc leucine zipper domain HLH PF00010.21 EMC82375.1 - 4.3e-16 58.3 10.1 2.4e-15 55.9 0.6 2.3 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DUF1394 PF07159.7 EMC82376.1 - 6.9e-176 583.6 0.1 8e-176 583.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.1 EMC82376.1 - 0.0074 14.5 0.1 0.031 12.4 0.0 1.8 1 1 1 2 2 2 1 WASH complex subunit 7, N-terminal V-ATPase_H_N PF03224.9 EMC82376.1 - 0.0091 15.1 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H NUDIX_4 PF14815.1 EMC82376.1 - 0.048 13.0 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain ArfGap PF01412.13 EMC82377.1 - 3.8e-36 123.3 0.0 1e-35 122.0 0.0 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EMC82377.1 - 8.5e-12 45.2 0.1 6e-11 42.5 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) SH3_9 PF14604.1 EMC82377.1 - 2.5e-10 39.7 0.1 4.8e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC82377.1 - 7.3e-10 38.9 0.5 1.9e-09 37.6 0.4 1.8 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EMC82377.1 - 1e-09 37.6 0.3 2.1e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 SH3 domain Ank PF00023.25 EMC82377.1 - 1.2e-09 37.4 0.5 0.0028 17.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMC82377.1 - 2.6e-07 30.9 0.4 0.0004 20.8 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC82377.1 - 5.9e-07 29.5 0.4 2.3e-05 24.4 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SH3_2 PF07653.12 EMC82377.1 - 8.9e-07 28.3 0.2 2.3e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.1 EMC82377.1 - 6.1e-06 25.9 0.6 0.22 11.8 0.0 3.6 4 0 0 4 4 2 2 Ankyrin repeat PH_3 PF14593.1 EMC82377.1 - 0.015 15.1 0.1 0.061 13.2 0.1 2.1 2 0 0 2 2 2 0 PH domain PH_9 PF15410.1 EMC82377.1 - 0.16 12.1 2.3 4.4 7.4 0.2 3.1 3 1 0 3 3 2 0 Pleckstrin homology domain DUF4404 PF14357.1 EMC82377.1 - 0.33 11.4 9.0 0.31 11.4 3.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) A2L_zn_ribbon PF08792.5 EMC82377.1 - 1.6 8.3 4.9 10 5.7 3.4 2.3 1 1 0 1 1 1 0 A2L zinc ribbon domain Guanylate_cyc PF00211.15 EMC82379.1 - 1.7e-87 291.5 0.0 2.5e-57 193.2 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 EMC82379.1 - 3.4e-25 88.3 0.1 1.1e-24 86.6 0.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Vma12 PF11712.3 EMC82379.1 - 1.1 8.9 4.6 7.2 6.3 0.1 3.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP-synt_ab PF00006.20 EMC82381.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sec20 PF03908.8 EMC82381.1 - 0.041 13.5 0.3 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 Sec20 TMEM71 PF15121.1 EMC82382.1 - 1.7e-53 180.4 1.7 2.3e-53 179.9 1.2 1.2 1 0 0 1 1 1 1 TMEM71 protein family PrgI PF12666.2 EMC82382.1 - 0.19 11.8 1.1 0.28 11.3 0.8 1.3 1 0 0 1 1 1 0 PrgI family protein COesterase PF00135.23 EMC82383.1 - 5.3e-123 411.5 0.0 7.5e-123 411.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Thyroglobulin_1 PF00086.13 EMC82383.1 - 1e-83 274.6 79.3 4.4e-15 54.7 1.9 11.2 11 0 0 11 11 11 10 Thyroglobulin type-1 repeat GCC2_GCC3 PF07699.8 EMC82383.1 - 3.3e-11 42.6 6.5 3.3e-11 42.6 4.5 3.0 2 1 1 3 3 3 1 GCC2 and GCC3 Abhydrolase_3 PF07859.8 EMC82383.1 - 0.00029 20.4 0.1 0.00058 19.5 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold SH2 PF00017.19 EMC82384.1 - 1.5e-21 76.0 0.4 6.4e-21 73.9 0.1 2.0 2 0 0 2 2 2 1 SH2 domain SH3_9 PF14604.1 EMC82384.1 - 1.5e-08 34.0 0.1 2.7e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC82384.1 - 3.4e-07 29.5 0.0 6.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC82384.1 - 0.0024 17.3 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DTW PF03942.10 EMC82384.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 DTW domain IGFBP PF00219.13 EMC82385.1 - 1.7e-14 54.0 22.0 1.7e-14 54.0 15.3 5.0 4 3 1 5 5 5 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 EMC82385.1 - 1.7e-09 37.6 4.7 1.7e-09 37.6 3.2 3.4 4 0 0 4 4 4 1 Thrombospondin type 1 domain Cys_knot PF00007.17 EMC82385.1 - 2e-09 37.4 8.1 2e-09 37.4 5.6 3.7 4 1 0 4 4 4 1 Cystine-knot domain VWC PF00093.13 EMC82385.1 - 2e-08 34.2 12.0 2e-08 34.2 8.3 5.2 4 3 0 4 4 4 1 von Willebrand factor type C domain Ndr PF03096.9 EMC82386.1 - 1.1e-124 414.5 0.0 1.3e-124 414.3 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 EMC82386.1 - 1.6e-15 57.6 0.0 2.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC82386.1 - 2.3e-05 24.0 0.0 0.00019 21.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_29 PF00777.13 EMC82387.1 - 1.5e-89 299.6 0.3 2e-89 299.2 0.0 1.3 2 0 0 2 2 2 1 Glycosyltransferase family 29 (sialyltransferase) PAXNEB PF05625.6 EMC82387.1 - 0.096 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein zf-H2C2_2 PF13465.1 EMC82389.1 - 8.6e-46 152.0 138.4 1.3e-07 31.5 0.1 21.3 22 1 0 22 22 22 14 Zinc-finger double domain zf-C2H2 PF00096.21 EMC82389.1 - 8.9e-39 129.5 157.8 0.00017 21.7 2.3 19.4 19 0 0 19 19 19 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC82389.1 - 5.7e-37 123.3 140.3 0.0014 18.8 0.3 19.4 19 0 0 19 19 19 18 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC82389.1 - 2.4e-21 74.6 125.0 0.00062 19.8 0.8 16.4 16 1 0 16 16 16 10 C2H2-type zinc-finger domain zf-Di19 PF05605.7 EMC82389.1 - 1.5e-12 47.4 99.1 0.0051 16.8 0.2 12.7 9 4 3 13 13 13 9 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMC82389.1 - 7.8e-05 22.7 5.3 7.8e-05 22.7 3.6 14.9 4 2 12 16 16 16 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC82389.1 - 0.00031 20.8 103.6 0.013 15.7 0.2 15.3 16 0 0 16 16 16 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC82389.1 - 0.045 13.9 0.4 0.045 13.9 0.3 16.0 19 0 0 19 19 19 0 Zinc-finger double-stranded RNA-binding MNHE PF01899.11 EMC82389.1 - 0.23 11.1 0.2 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Rad50_zn_hook PF04423.9 EMC82389.1 - 1.2 8.6 16.0 0.21 11.0 0.1 4.7 6 0 0 6 6 6 0 Rad50 zinc hook motif KH_1 PF00013.24 EMC82390.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC82390.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF676 PF05057.9 EMC82391.1 - 1.1e-57 194.8 0.0 1.8e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 EMC82391.1 - 1.2e-25 89.3 10.5 6.4e-17 61.3 0.8 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3657) PGAP1 PF07819.8 EMC82391.1 - 6.3e-06 25.9 0.1 3.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.10 EMC82391.1 - 0.00056 19.0 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase LRR_4 PF12799.2 EMC82392.1 - 3.3e-31 106.3 42.6 4.6e-09 35.6 0.8 4.6 1 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC82392.1 - 1.2e-22 79.4 38.9 4e-10 39.2 4.0 4.1 1 1 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EMC82392.1 - 1.1e-15 55.2 24.6 0.032 14.2 0.1 7.4 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC82392.1 - 5.9e-13 46.7 28.1 0.15 12.3 0.7 7.0 6 0 0 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EMC82392.1 - 2e-06 27.2 22.5 0.11 12.6 0.0 6.7 5 1 2 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.1 EMC82392.1 - 0.016 14.7 5.7 0.033 13.7 0.7 2.7 1 1 1 2 2 2 0 Leucine-rich repeat Ion_trans_2 PF07885.11 EMC82394.1 - 3e-35 119.7 20.6 2.2e-18 65.7 2.8 2.9 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.26 EMC82394.1 - 4.2e-06 26.1 7.0 0.0043 16.3 0.0 2.4 1 1 1 2 2 2 2 Ion transport protein CytochromB561_N PF09786.4 EMC82394.1 - 0.0047 15.4 0.1 0.0071 14.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal IRK PF01007.15 EMC82394.1 - 0.13 11.0 1.6 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel TRAPPC9-Trs120 PF08626.6 EMC82395.1 - 2.8e-08 31.6 0.0 3.1e-08 31.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC9-Trs120 PF08626.6 EMC82396.1 - 0.007 13.7 0.0 0.0073 13.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Homeobox PF00046.24 EMC82398.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain PRP21_like_P PF12230.3 EMC82398.1 - 0.0087 15.5 0.5 1 8.8 0.0 2.7 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_4 PF13894.1 EMC82398.1 - 0.27 11.6 44.7 0.76 10.2 0.1 7.9 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC82398.1 - 8.9 6.4 45.6 1.1 9.3 1.2 7.1 4 2 1 6 6 6 0 C2H2 type zinc-finger (2 copies) RBFA PF02033.13 EMC82399.1 - 4.1e-07 29.9 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Ribosome-binding factor A 2-Hacid_dh_C PF02826.14 EMC82400.1 - 2.2e-61 206.1 0.1 2.8e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC82400.1 - 1.1e-17 63.7 0.0 1.3e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC82400.1 - 3.5e-10 39.9 0.2 6.2e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EMC82400.1 - 0.005 17.3 0.0 0.0087 16.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EMC82400.1 - 0.006 16.5 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain IlvN PF07991.7 EMC82400.1 - 0.034 13.5 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 EMC82400.1 - 0.035 13.6 0.2 0.14 11.7 0.1 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 EMC82400.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EMC82400.1 - 0.085 12.6 0.0 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMC82401.1 - 7.8e-60 201.0 0.1 1.4e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC82401.1 - 1.5e-22 79.5 0.1 1.8e-22 79.2 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC82401.1 - 8.5e-12 45.2 0.6 1.9e-11 44.1 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EMC82401.1 - 0.00019 21.9 0.1 0.00092 19.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EMC82401.1 - 0.00029 21.1 0.0 0.00079 19.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_N PF05222.10 EMC82401.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AdoHcyase_NAD PF00670.16 EMC82401.1 - 0.0029 17.4 0.5 0.67 9.7 0.0 2.4 2 1 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 EMC82401.1 - 0.0055 16.2 0.4 0.044 13.3 0.1 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMC82401.1 - 0.008 16.1 2.1 0.14 12.2 0.0 3.4 4 0 0 4 4 4 1 TrkA-N domain IlvN PF07991.7 EMC82401.1 - 0.019 14.3 0.1 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 EMC82401.1 - 0.11 12.8 0.0 0.73 10.1 0.0 2.3 2 1 0 2 2 2 0 XdhC Rossmann domain HSBP1 PF06825.7 EMC82402.1 - 7.4e-11 41.4 2.9 1.8e-10 40.1 2.0 1.6 1 1 0 1 1 1 1 Heat shock factor binding protein 1 YvrJ PF12841.2 EMC82402.1 - 0.03 13.6 1.0 5.5 6.3 0.1 2.1 2 0 0 2 2 2 0 YvrJ protein family DUF1974 PF09317.6 EMC82402.1 - 0.034 13.5 0.0 0.039 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF4279 PF14106.1 EMC82402.1 - 0.037 13.8 0.2 0.042 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) UCH_1 PF13423.1 EMC82402.1 - 0.13 11.6 0.2 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase GvpK PF05121.7 EMC82402.1 - 0.14 11.9 2.2 0.29 10.9 0.2 1.9 1 1 1 2 2 2 0 Gas vesicle protein K Erythro-docking PF09277.6 EMC82402.1 - 0.15 11.7 0.3 0.27 10.9 0.2 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking PQ-loop PF04193.9 EMC82403.1 - 2.8e-30 103.6 8.7 1.6e-19 69.2 0.1 3.7 3 1 1 4 4 4 2 PQ loop repeat MtN3_slv PF03083.11 EMC82403.1 - 0.012 15.4 10.1 0.015 15.1 1.4 2.9 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 EMC82403.1 - 0.071 13.6 8.6 0.23 11.9 0.3 3.1 3 1 1 4 4 4 0 ER lumen protein retaining receptor DUF2678 PF10856.3 EMC82403.1 - 0.099 12.3 2.6 0.095 12.4 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) BTB_2 PF02214.17 EMC82404.1 - 4.3e-28 97.3 0.0 9.5e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 EMC82404.1 - 6e-28 97.4 3.9 6e-28 97.4 2.7 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EMC82404.1 - 5.9e-14 51.5 4.8 1.3e-13 50.4 1.6 2.4 2 0 0 2 2 2 1 Ion channel RHD PF00554.17 EMC82405.1 - 7.6e-26 90.8 0.1 2.7e-25 89.0 0.0 2.0 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 EMC82405.1 - 3.8e-06 26.8 0.0 1.5e-05 24.8 0.0 2.2 1 0 0 1 1 1 1 IPT/TIG domain E1-E2_ATPase PF00122.15 EMC82406.1 - 8.4e-25 87.1 0.0 1.7e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMC82406.1 - 9e-16 58.9 0.0 2.4e-15 57.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC82406.1 - 3e-14 53.6 0.0 2.9e-13 50.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC82406.1 - 2.9e-06 27.1 0.0 1.4e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC82406.1 - 0.00038 20.1 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF443 PF04276.7 EMC82406.1 - 0.022 14.2 0.3 0.022 14.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF443) DUF4174 PF13778.1 EMC82406.1 - 0.071 13.2 0.2 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) zf-H2C2_2 PF13465.1 EMC82407.1 - 9e-30 101.4 40.5 3.8e-08 33.2 0.7 9.3 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC82407.1 - 8.5e-25 85.5 58.7 0.00011 22.3 0.1 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC82407.1 - 3.9e-21 73.7 51.5 0.00011 22.3 0.4 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC82407.1 - 3.3e-17 62.1 34.6 0.0012 18.9 0.9 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC82407.1 - 1.2e-14 53.9 44.0 0.0022 18.1 0.3 7.9 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC82407.1 - 0.01 15.9 32.1 0.42 10.7 1.3 7.2 3 3 4 7 7 7 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 EMC82407.1 - 0.019 14.6 18.6 1 9.0 0.2 4.6 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 EMC82407.1 - 0.029 14.2 45.9 0.056 13.3 0.3 7.7 8 0 0 8 8 8 0 C2H2-type zinc finger BolA PF01722.13 EMC82407.1 - 0.14 12.0 2.4 31 4.6 0.1 3.7 3 0 0 3 3 3 0 BolA-like protein DUF2225 PF09986.4 EMC82407.1 - 0.28 10.5 2.4 0.32 10.4 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.7 EMC82407.1 - 0.35 11.0 23.8 0.049 13.7 1.2 4.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Drf_FH1 PF06346.7 EMC82410.1 - 6.5e-17 61.4 39.6 1.7e-08 34.1 12.7 2.5 1 1 1 2 2 2 2 Formin Homology Region 1 zf-CCHC_6 PF15288.1 EMC82410.1 - 1.8e-06 27.4 25.5 66 3.2 0.0 10.8 1 1 20 21 21 21 11 Zinc knuckle AKAP95 PF04988.7 EMC82411.1 - 1.8e-69 232.7 6.2 2.9e-69 232.0 4.3 1.3 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 EMC82411.1 - 5.8e-05 23.1 5.0 0.03 14.4 0.1 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 EMC82411.1 - 0.13 12.4 3.2 3 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) zf-Di19 PF05605.7 EMC82411.1 - 0.18 11.9 0.2 0.18 11.9 0.2 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CDC45 PF02724.9 EMC82411.1 - 0.83 7.6 15.3 1.2 7.0 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_4 PF13894.1 EMC82411.1 - 0.92 9.9 5.7 0.86 10.0 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC82411.1 - 0.98 9.7 8.2 0.14 12.4 1.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MSA-2c PF12238.3 EMC82411.1 - 2.6 7.6 8.5 0.81 9.3 0.1 2.9 2 1 1 3 3 3 0 Merozoite surface antigen 2c AKAP95 PF04988.7 EMC82412.1 - 1.1e-73 246.4 6.6 2.2e-73 245.4 4.6 1.5 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) DUF3505 PF12013.3 EMC82412.1 - 0.051 13.8 3.4 0.65 10.2 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 EMC82412.1 - 0.16 12.1 5.7 2 8.5 0.4 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC82412.1 - 4 7.7 5.3 0.66 10.2 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type IGFBP PF00219.13 EMC82414.1 - 7.7e-07 29.5 42.3 0.63 10.6 2.1 5.8 1 1 3 4 4 4 3 Insulin-like growth factor binding protein p450 PF00067.17 EMC82417.1 - 1.9e-77 260.7 0.0 2.2e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPRR2 PF14820.1 EMC82418.1 - 0.52 10.2 143.5 20 5.1 8.6 9.8 1 1 3 4 4 4 0 Small proline-rich 2 Retinal PF15449.1 EMC82419.1 - 1.2e-06 26.5 21.4 3.5e+02 -1.5 14.8 3.6 1 1 0 1 1 1 0 Retinal protein Cadherin PF00028.12 EMC82420.1 - 3.3e-76 251.6 10.3 4.7e-19 68.4 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC82420.1 - 3.6e-58 195.8 1.1 8.9e-58 194.5 0.8 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC82420.1 - 0.00034 20.1 0.0 2.6 7.6 0.0 3.7 3 1 0 3 3 3 2 Cadherin-like ASFV_J13L PF05568.6 EMC82420.1 - 0.005 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein 7TM_GPCR_Srw PF10324.4 EMC82420.1 - 0.11 11.6 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Lyase_1 PF00206.15 EMC82421.1 - 2.5e-122 407.9 0.1 3.2e-122 407.6 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EMC82421.1 - 2.1e-28 98.1 0.1 1.7e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 Fumarase C C-terminus FAD_binding_2 PF00890.19 EMC82422.1 - 2e-127 425.5 2.4 2.5e-127 425.2 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMC82422.1 - 1e-43 148.2 0.0 1.7e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EMC82422.1 - 4.6e-08 33.1 0.0 0.0055 16.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC82422.1 - 4.2e-06 26.0 0.3 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EMC82422.1 - 0.00013 21.0 3.9 0.055 12.3 1.5 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 EMC82422.1 - 0.00022 20.2 0.1 0.0038 16.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMC82422.1 - 0.0049 15.9 0.2 0.0077 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMC82422.1 - 0.19 10.1 1.8 0.73 8.2 0.2 2.5 3 0 0 3 3 3 0 HI0933-like protein PTS_IIA PF02255.11 EMC82423.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit PIN_3 PF13470.1 EMC82423.1 - 0.4 11.3 4.2 2.4 8.8 2.9 2.3 1 1 0 1 1 1 0 PIN domain Exonuc_VII_L PF02601.10 EMC82423.1 - 1.2 8.2 7.9 1.6 7.8 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EMC82423.1 - 3 7.7 12.1 1e+02 2.7 8.4 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SNF PF00209.13 EMC82424.1 - 4.8e-177 589.5 32.0 5.8e-177 589.3 22.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2614 PF11023.3 EMC82424.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) CLPTM1 PF05602.7 EMC82425.1 - 2.4e-131 438.4 3.0 3e-131 438.1 2.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Acyltransferase PF01553.16 EMC82426.1 - 6.2e-17 61.2 0.0 1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_6 PF13405.1 EMC82426.1 - 1.7e-12 46.0 0.0 0.015 15.1 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EMC82426.1 - 6.5e-12 44.8 0.1 1.5e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC82426.1 - 7.9e-11 40.4 0.3 0.0038 16.4 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EMC82426.1 - 2.7e-10 40.2 0.2 1e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC82426.1 - 6.9e-05 22.0 0.7 0.64 9.4 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EMC82426.1 - 0.0072 16.0 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand zf-CHCC PF10276.4 EMC82428.1 - 2.5e-19 68.8 0.5 3.4e-19 68.4 0.4 1.2 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 EMC82428.1 - 0.084 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Thiolase_C PF02803.13 EMC82428.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Thiolase, C-terminal domain Homeobox_KN PF05920.6 EMC82431.1 - 8.7e-15 54.1 0.3 2.3e-14 52.7 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC82431.1 - 2e-07 30.5 0.4 3.8e-07 29.6 0.3 1.4 1 0 0 1 1 1 1 Homeobox domain Dicty_REP PF05086.7 EMC82431.1 - 0.029 12.1 1.2 0.038 11.7 0.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Homez PF11569.3 EMC82431.1 - 0.05 12.6 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Astro_capsid PF03115.9 EMC82431.1 - 0.68 8.1 5.2 0.91 7.6 3.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF3729 PF12526.3 EMC82431.1 - 2.5 9.4 15.0 1.4 10.3 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Nop14 PF04147.7 EMC82431.1 - 5.3 4.8 15.3 7.5 4.3 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EMC82432.1 - 3.3e-55 185.9 0.2 3.6e-55 185.8 0.1 1.0 1 0 0 1 1 1 1 FAM176 family Myc_target_1 PF15179.1 EMC82432.1 - 0.037 13.6 0.1 0.044 13.3 0.1 1.0 1 0 0 1 1 1 0 Myc target protein 1 TFIIE-A_C-term PF11521.3 EMC82432.1 - 0.19 11.7 1.7 0.26 11.2 1.2 1.3 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF755 PF05501.6 EMC82432.1 - 0.96 9.5 7.5 1.4 8.9 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CDC45 PF02724.9 EMC82432.1 - 5.3 4.9 6.5 6 4.7 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Gal_Lectin PF02140.13 EMC82433.1 - 6.6e-37 125.6 5.2 9.8e-19 67.4 0.6 2.2 2 0 0 2 2 2 2 Galactose binding lectin domain Zn_Tnp_IS91 PF14319.1 EMC82433.1 - 3.8 7.0 6.7 0.83 9.1 0.3 2.6 3 0 0 3 3 3 0 Transposase zinc-binding domain Ribosomal_L19 PF01245.15 EMC82434.1 - 3.8e-19 68.5 0.0 5.9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 GCFC PF07842.7 EMC82435.1 - 9.9e-28 97.2 3.6 3.3e-27 95.5 2.5 1.9 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein NTR2 PF15458.1 EMC82435.1 - 0.00066 18.9 4.5 0.00066 18.9 3.1 2.7 3 0 0 3 3 3 1 Nineteen complex-related protein 2 DUF309 PF03745.9 EMC82435.1 - 0.09 12.2 0.2 0.47 9.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF309) DUF1436 PF07262.6 EMC82435.1 - 0.15 11.5 2.7 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) SH3_9 PF14604.1 EMC82436.1 - 2e-68 225.8 6.4 2.2e-15 55.9 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.23 EMC82436.1 - 1.8e-66 219.3 9.3 4.3e-16 58.0 0.1 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 EMC82436.1 - 1.3e-59 197.5 0.7 2.2e-13 49.4 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.15 EMC82436.1 - 9.8e-44 149.3 0.1 9.8e-44 149.3 0.1 3.2 2 1 0 2 2 1 1 RhoGEF domain EF-hand_4 PF12763.2 EMC82436.1 - 6.2e-26 90.1 0.0 1.8e-13 50.1 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 EMC82436.1 - 3e-20 71.8 0.0 6.9e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 EMC82436.1 - 1.7e-09 36.2 0.2 0.0046 16.1 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EMC82436.1 - 5.6e-09 36.0 0.0 3.3e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC82436.1 - 1.5e-06 27.5 0.4 2.2 8.3 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain PH PF00169.24 EMC82436.1 - 2.7e-05 24.3 0.2 0.00015 21.9 0.1 2.4 1 0 0 1 1 1 1 PH domain EF-hand_8 PF13833.1 EMC82436.1 - 0.0013 18.3 0.0 0.16 11.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC82436.1 - 0.042 13.2 1.1 7.3 6.1 0.1 3.1 3 0 0 3 3 3 0 EF hand DUF3104 PF11302.3 EMC82436.1 - 0.14 11.5 6.2 15 5.0 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3104) ADH_zinc_N PF00107.21 EMC82438.1 - 2.1e-23 82.2 0.1 4.2e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC82438.1 - 1e-15 58.7 0.0 3.9e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC82438.1 - 5.2e-11 42.2 0.1 3.6e-09 36.3 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain RRM_1 PF00076.17 EMC82439.1 - 3.3e-16 58.6 0.2 2.4e-15 55.9 0.0 2.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82439.1 - 2.7e-11 43.2 0.0 6.1e-11 42.1 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82439.1 - 7.9e-09 35.2 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.2 EMC82439.1 - 0.045 13.3 0.2 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) FKBP_C PF00254.23 EMC82440.1 - 1.4e-30 105.1 0.0 1.6e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4613 PF15390.1 EMC82441.1 - 0 1053.7 0.0 0 1053.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) DUF4613 PF15390.1 EMC82442.1 - 0 1035.6 0.5 0 1035.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) MFS_2 PF13347.1 EMC82443.1 - 9.9e-90 300.9 18.7 1.1e-89 300.7 13.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 EMC82443.1 - 1.1e-09 37.4 26.4 2.8e-09 36.1 14.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily SEP PF08059.8 EMC82444.1 - 8.8e-27 93.2 0.4 2e-26 92.0 0.3 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EMC82444.1 - 8.3e-15 54.6 0.1 2.8e-14 52.9 0.1 1.9 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 EMC82444.1 - 0.0012 18.2 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 Spt20 family AAA PF00004.24 EMC82445.1 - 1.1e-47 161.4 0.0 7.7e-41 139.3 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 EMC82445.1 - 6e-18 64.5 0.1 1.5e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.1 EMC82445.1 - 3.7e-08 33.5 0.7 1.6e-05 24.9 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMC82445.1 - 4.5e-06 26.8 0.1 0.0033 17.5 0.1 3.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMC82445.1 - 8.5e-06 25.3 0.0 6.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EMC82445.1 - 7.1e-05 22.7 0.0 0.00026 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 EMC82445.1 - 0.00024 21.1 0.0 0.57 10.2 0.0 3.4 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.1 EMC82445.1 - 0.00043 19.9 0.0 0.031 14.0 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EMC82445.1 - 0.0028 17.9 0.8 0.036 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC82445.1 - 0.0039 18.0 1.4 0.014 16.1 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMC82445.1 - 0.0039 16.9 0.1 0.046 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EMC82445.1 - 0.011 15.8 0.0 0.048 13.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 EMC82445.1 - 0.012 14.8 0.0 0.2 10.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EMC82445.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMC82445.1 - 0.02 14.2 0.0 0.055 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EMC82445.1 - 0.03 13.3 0.0 0.091 11.7 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMC82445.1 - 0.041 12.5 0.0 0.15 10.7 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus AAA_33 PF13671.1 EMC82445.1 - 0.053 13.3 0.6 0.2 11.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 EMC82445.1 - 0.06 13.0 0.0 0.38 10.3 0.0 2.4 2 1 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EMC82445.1 - 0.061 12.7 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EMC82445.1 - 0.16 11.5 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain Rnk_N PF14760.1 EMC82446.1 - 0.026 14.6 0.7 4.7 7.3 0.0 2.6 1 1 1 2 2 2 0 Rnk N-terminus Kelch_6 PF13964.1 EMC82447.1 - 1e-46 155.2 9.2 2.7e-10 39.9 0.0 6.3 2 1 4 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EMC82447.1 - 2.1e-46 155.2 12.4 2.4e-12 46.1 0.0 7.1 7 1 0 7 7 7 5 Kelch motif BACK PF07707.10 EMC82447.1 - 3.9e-31 106.9 0.3 8.8e-31 105.8 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 EMC82447.1 - 7.3e-27 92.8 3.4 5.7e-08 32.4 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 EMC82447.1 - 4e-24 84.7 0.9 9.5e-24 83.5 0.6 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 EMC82447.1 - 1.9e-22 78.0 1.5 6.1e-05 22.6 0.0 6.9 7 1 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 EMC82447.1 - 3.2e-17 62.1 5.2 1.7e-05 24.8 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC82447.1 - 4e-16 58.5 12.8 0.00062 19.6 0.1 7.0 7 0 0 7 7 7 4 Kelch motif DUF3342 PF11822.3 EMC82447.1 - 0.02 14.0 0.5 0.041 13.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DUF1668 PF07893.8 EMC82447.1 - 0.022 13.9 0.0 0.48 9.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1668) PQQ_3 PF13570.1 EMC82447.1 - 0.11 12.8 3.8 27 5.1 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain DUF2305 PF10230.4 EMC82449.1 - 5.1e-85 285.1 0.0 6.3e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EMC82449.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC82449.1 - 0.00011 22.0 0.0 0.00021 21.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EMC82449.1 - 0.0014 18.2 0.0 0.0069 16.0 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 EMC82449.1 - 0.056 12.7 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EMC82449.1 - 0.13 11.2 0.1 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TGF_beta PF00019.15 EMC82450.1 - 5.8e-38 129.3 0.3 8.2e-38 128.8 0.2 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC82450.1 - 3e-17 62.7 0.0 4.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide PX PF00787.19 EMC82451.1 - 1.6e-12 47.1 1.3 3.9e-12 45.9 0.1 2.1 2 0 0 2 2 2 1 PX domain Myc_N PF01056.13 EMC82451.1 - 9.4 5.2 11.9 41 3.1 7.3 2.2 1 1 1 2 2 2 0 Myc amino-terminal region CAF1A PF12253.3 EMC82452.1 - 0.045 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A WD40 PF00400.27 EMC82453.1 - 2e-49 163.7 10.6 5.2e-09 35.6 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC82453.1 - 1.6e-05 24.7 3.0 0.086 12.5 0.5 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Collagen PF01391.13 EMC82453.1 - 0.0001 21.7 26.5 0.0001 21.7 18.4 9.4 5 1 3 8 8 8 2 Collagen triple helix repeat (20 copies) RNA_pol_Rpb4 PF03874.11 EMC82454.1 - 9e-29 99.8 5.2 1e-28 99.7 3.6 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rop PF01815.11 EMC82454.1 - 0.00034 19.9 0.8 0.00087 18.6 0.6 1.6 1 0 0 1 1 1 1 Rop protein Birna_VP5 PF03042.9 EMC82454.1 - 0.049 13.1 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP5 protein Maelstrom PF13017.1 EMC82454.1 - 0.049 13.1 0.4 0.055 12.9 0.3 1.0 1 0 0 1 1 1 0 piRNA pathway germ-plasm component AMMECR1 PF01871.12 EMC82455.1 - 4.6e-45 152.8 0.0 6.3e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DNA_pol3_delta PF06144.8 EMC82456.1 - 0.13 11.8 1.5 0.2 11.1 1.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit OB_RNB PF08206.6 EMC82457.1 - 0.14 11.6 0.1 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain UDP-g_GGTase PF06427.6 EMC82458.1 - 6.2e-78 260.9 0.1 5.6e-76 254.5 0.0 3.4 4 0 0 4 4 4 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EMC82458.1 - 1.2e-06 28.1 0.6 1.2e-06 28.1 0.4 3.1 4 0 0 4 4 4 1 Glycosyl transferase family 8 Sulfotransfer_2 PF03567.9 EMC82459.1 - 1.4e-48 165.8 0.5 1.9e-48 165.3 0.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family Spore_III_AB PF09548.5 EMC82459.1 - 0.052 13.2 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PH PF00169.24 EMC82460.1 - 1.6e-09 37.9 0.1 2.1e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 PH domain YppG PF14179.1 EMC82460.1 - 0.022 15.3 1.4 0.033 14.7 1.0 1.2 1 0 0 1 1 1 0 YppG-like protein TCRP1 PF14944.1 EMC82461.1 - 1.1e-108 361.6 53.2 1.2e-108 361.4 36.9 1.0 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 RhoGEF PF00621.15 EMC82462.1 - 6.7e-50 169.4 6.8 6.7e-50 169.4 4.7 1.6 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 EMC82462.1 - 1.4e-12 46.9 0.2 2.7e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC82462.1 - 1.9e-10 40.8 0.7 3.9e-10 39.8 0.5 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EMC82462.1 - 3.2e-10 39.2 1.9 5.9e-10 38.3 1.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC82462.1 - 6.2e-08 32.0 0.0 1.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.1 EMC82462.1 - 0.029 14.2 0.2 0.27 11.1 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain GETHR PF05671.6 EMC82464.1 - 0.043 12.9 0.1 2.5 7.3 0.0 3.2 1 1 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) G-alpha PF00503.15 EMC82465.1 - 1.3e-98 330.2 2.8 1.6e-98 329.9 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC82465.1 - 6e-12 45.1 0.2 2.2e-11 43.3 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC82466.1 - 3.3e-119 398.0 3.9 3.7e-119 397.8 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC82466.1 - 9.6e-13 47.7 3.1 4.5e-11 42.2 0.1 2.7 3 1 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC82466.1 - 0.0056 16.6 0.1 0.79 9.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SPT16 PF08644.6 EMC82466.1 - 0.036 13.9 0.4 0.061 13.1 0.2 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Miro PF08477.8 EMC82466.1 - 0.11 13.0 1.8 15 6.1 0.7 2.9 2 1 0 2 2 2 0 Miro-like protein LMSTEN PF07988.7 EMC82466.1 - 0.11 11.8 1.8 0.12 11.6 0.2 1.9 2 0 0 2 2 2 0 LMSTEN motif Collagen PF01391.13 EMC82468.1 - 1.7e-42 142.8 211.8 1e-05 24.9 7.4 12.5 1 1 14 15 15 15 14 Collagen triple helix repeat (20 copies) Carb_anhydrase PF00194.16 EMC82469.1 - 1.9e-43 148.2 0.0 5e-42 143.6 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF4570 PF15134.1 EMC82470.1 - 3.6e-28 97.5 3.3 8.3e-20 70.6 1.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4570) SPG48 PF14764.1 EMC82470.1 - 0.029 12.8 0.3 0.038 12.5 0.2 1.1 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking zf-H2C2_2 PF13465.1 EMC82471.1 - 1.1e-30 104.3 39.3 1.5e-06 28.2 0.1 6.1 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC82471.1 - 2.7e-20 71.3 52.4 1.2e-06 28.4 1.3 6.7 6 1 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC82471.1 - 1.9e-10 40.2 43.5 0.00077 19.6 0.7 6.2 6 1 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC82471.1 - 1.8e-05 24.7 34.6 0.45 10.7 0.2 6.3 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.7 EMC82471.1 - 0.0096 16.0 21.4 0.41 10.8 5.8 3.0 1 1 2 3 3 3 3 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 EMC82471.1 - 0.016 15.0 3.1 0.016 15.0 2.2 3.5 3 1 0 3 3 3 0 Transposase zinc-ribbon domain C1_1 PF00130.17 EMC82471.1 - 0.029 14.1 4.1 0.029 14.1 2.8 4.2 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.13 EMC82471.1 - 0.033 14.1 1.5 6.9 6.7 0.0 2.6 3 0 0 3 3 3 0 BolA-like protein zf-RING_3 PF14369.1 EMC82471.1 - 0.039 13.9 13.0 1.7 8.6 0.3 5.0 5 0 0 5 5 5 0 zinc-finger zf-Sec23_Sec24 PF04810.10 EMC82471.1 - 0.047 13.2 17.3 0.31 10.6 1.4 4.9 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger DUF2489 PF10675.4 EMC82471.1 - 0.067 12.8 0.2 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) zf-C2H2_6 PF13912.1 EMC82471.1 - 0.086 12.7 0.6 0.086 12.7 0.4 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger DUF2180 PF09947.4 EMC82471.1 - 0.13 12.0 15.2 0.19 11.4 0.1 4.1 2 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Zn-ribbon_8 PF09723.5 EMC82471.1 - 0.15 12.0 20.8 8.7 6.3 1.5 4.9 2 2 1 3 3 3 0 Zinc ribbon domain XPA_N PF01286.13 EMC82471.1 - 0.33 10.6 15.5 4 7.1 0.0 5.1 5 0 0 5 5 5 0 XPA protein N-terminal zf-met PF12874.2 EMC82471.1 - 0.57 10.4 31.2 1.8 8.8 0.2 6.3 6 1 1 7 7 7 0 Zinc-finger of C2H2 type C1_3 PF07649.7 EMC82471.1 - 0.77 9.8 0.1 0.77 9.8 0.0 5.2 5 0 0 5 5 5 0 C1-like domain Rep_fac-A_C PF08646.5 EMC82471.1 - 0.82 9.3 12.6 2.9 7.5 2.1 2.4 1 1 1 2 2 2 0 Replication factor-A C terminal domain FYDLN_acid PF09538.5 EMC82471.1 - 1.6 9.3 8.2 37 4.9 0.6 3.7 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.2 EMC82471.1 - 1.7 8.7 26.3 7.1 6.7 4.4 4.4 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DZR PF12773.2 EMC82471.1 - 4.1 7.3 20.0 27 4.6 6.5 3.5 1 1 1 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.11 EMC82471.1 - 4.8 7.1 28.8 0.82 9.5 1.4 5.1 4 1 1 5 5 5 0 AN1-like Zinc finger GAGA PF09237.6 EMC82471.1 - 5.8 6.5 10.7 7.7 6.1 0.1 3.5 2 2 2 4 4 4 0 GAGA factor Glyco_transf_54 PF04666.8 EMC82472.1 - 9.3e-109 362.7 1.3 1.3e-108 362.3 0.9 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.12 EMC82472.1 - 0.0066 16.1 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Pro-NT_NN PF07421.6 EMC82473.1 - 1.6e-79 265.2 1.3 1.8e-79 265.1 0.9 1.0 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor Homeobox PF00046.24 EMC82474.1 - 4.7e-24 83.7 6.2 1.2e-23 82.4 4.3 1.7 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 EMC82474.1 - 6.2e-10 38.2 0.6 1.6e-09 36.9 0.4 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 EMC82474.1 - 0.00037 20.1 0.1 0.00098 18.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Staygreen PF12638.2 EMC82474.1 - 0.044 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Staygreen protein IQ PF00612.22 EMC82475.1 - 8.1e-06 25.0 0.1 1.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif ERbeta_N PF12497.3 EMC82475.1 - 0.00017 21.4 1.7 0.00029 20.6 1.2 1.3 1 0 0 1 1 1 1 Estrogen receptor beta LRR_4 PF12799.2 EMC82476.1 - 7e-27 92.5 49.1 1.1e-07 31.3 0.8 7.8 5 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC82476.1 - 1.6e-19 69.4 45.1 1.6e-07 31.0 4.5 6.5 2 2 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EMC82476.1 - 3.2e-10 38.5 48.4 1.5 9.1 0.3 11.8 10 2 2 12 12 12 8 Leucine Rich Repeat LRR_7 PF13504.1 EMC82476.1 - 9.8e-05 21.9 48.5 2 8.9 0.1 12.2 13 1 0 13 13 13 3 Leucine rich repeat LRR_6 PF13516.1 EMC82476.1 - 0.0005 19.8 47.2 0.45 10.7 0.2 11.4 9 2 3 12 12 12 4 Leucine Rich repeat LRR_9 PF14580.1 EMC82476.1 - 0.0038 16.8 10.3 0.036 13.6 0.1 3.9 2 2 2 4 4 4 3 Leucine-rich repeat SNF PF00209.13 EMC82477.1 - 4.7e-225 747.9 31.0 5.7e-225 747.7 21.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Peptidase_M50 PF02163.17 EMC82477.1 - 0.031 13.2 0.0 0.32 9.9 0.0 2.4 1 1 0 1 1 1 0 Peptidase family M50 DUF1077 PF06417.7 EMC82477.1 - 0.11 11.8 1.4 1.4 8.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1077) RVT_1 PF00078.22 EMC82478.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PSP1 PF04468.7 EMC82479.1 - 0.019 14.8 0.3 0.053 13.5 0.1 1.8 2 0 0 2 2 2 0 PSP1 C-terminal conserved region 7tm_1 PF00001.16 EMC82480.1 - 5.1e-39 133.9 34.1 2.1e-37 128.6 23.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82480.1 - 1.9e-10 40.3 33.2 3.8e-10 39.3 23.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TILa PF12714.2 EMC82481.1 - 2 8.2 6.4 0.42 10.4 1.9 1.8 1 1 0 2 2 2 0 TILa domain Yae1_N PF09811.4 EMC82482.1 - 0.41 10.2 48.5 0.11 12.0 4.8 5.2 1 1 2 3 3 3 0 Essential protein Yae1, N terminal Cadherin PF00028.12 EMC82483.1 - 6e-84 276.4 7.0 3.4e-19 68.8 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC82483.1 - 4.4e-56 189.0 1.4 9.5e-56 187.9 1.0 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC82483.1 - 1.5e-05 24.5 0.0 0.067 12.7 0.0 3.8 4 0 0 4 4 4 2 Cadherin-like Sigma_1s PF02454.11 EMC82483.1 - 0.045 13.5 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Sigma 1s protein ASFV_J13L PF05568.6 EMC82483.1 - 0.047 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF443 PF04276.7 EMC82483.1 - 0.055 12.8 0.3 0.088 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF912 PF06024.7 EMC82483.1 - 0.069 13.2 0.5 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EMC82483.1 - 0.096 12.3 0.2 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 EMC82483.1 - 0.18 11.4 0.3 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 Rifin/stevor family IncA PF04156.9 EMC82483.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 IncA protein Yae1_N PF09811.4 EMC82485.1 - 1.3e-13 50.2 44.1 1.5e+04 -5.4 30.6 4.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Arfaptin PF06456.8 EMC82487.1 - 2.4e-46 157.9 1.9 2.8e-46 157.7 1.3 1.0 1 0 0 1 1 1 1 Arfaptin-like domain Sad1_UNC PF07738.8 EMC82488.1 - 1.7e-19 69.9 0.0 2.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal 7tm_1 PF00001.16 EMC82489.1 - 1.1e-25 90.3 6.0 1.4e-25 89.9 4.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC82489.1 - 7.1e-07 29.1 1.1 7.1e-07 29.1 0.7 2.4 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srv PF10323.4 EMC82489.1 - 0.00016 20.9 6.6 0.00022 20.4 4.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC82489.1 - 0.00029 20.0 4.8 0.00037 19.6 3.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2189 PF09955.4 EMC82489.1 - 0.68 9.8 8.7 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) RhoGAP PF00620.22 EMC82491.1 - 2.6e-27 95.2 0.1 5.3e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Guanylate_cyc PF00211.15 EMC82492.1 - 5.5e-62 208.4 0.0 9e-62 207.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 EMC82492.1 - 2.6e-61 206.6 2.9 2e-60 203.7 2.0 2.1 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.10 EMC82492.1 - 4.6e-07 29.5 0.0 7.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding HNOBA PF07701.9 EMC82493.1 - 1.4e-72 243.4 0.1 3.4e-72 242.2 0.0 1.7 2 0 0 2 2 2 1 Heme NO binding associated Guanylate_cyc PF00211.15 EMC82493.1 - 2.9e-65 219.0 0.0 4.3e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 EMC82493.1 - 9e-52 175.0 0.1 1.5e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding ASC PF00858.19 EMC82494.1 - 1.5e-88 297.3 7.0 1.9e-88 297.0 4.9 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Trp_dioxygenase PF03301.8 EMC82495.1 - 7e-165 548.2 5.1 8.2e-165 548.0 3.5 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Peptidase_C1 PF00112.18 EMC82496.1 - 1.3e-58 198.5 3.5 1.5e-58 198.2 2.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EMC82496.1 - 4.9e-07 28.6 0.1 0.0011 17.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.1 EMC82496.1 - 0.054 13.8 0.5 0.24 11.7 0.4 1.9 1 1 0 1 1 1 0 Peptidase_C39 like family Inhibitor_I29 PF08246.7 EMC82496.1 - 0.069 13.4 0.2 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) CTDII PF01556.13 EMC82499.1 - 9.2e-19 67.1 0.1 2e-14 53.2 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMC82499.1 - 4.8e-13 48.9 17.1 9.1e-13 48.0 11.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EMC82499.1 - 0.00054 19.6 8.2 0.023 14.3 0.3 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EMC82499.1 - 0.078 13.3 4.2 0.18 12.1 2.9 1.6 1 0 0 1 1 1 0 Cytochrome c3 A2L_zn_ribbon PF08792.5 EMC82499.1 - 4.3 6.9 11.7 11 5.6 1.2 3.7 2 2 1 3 3 3 0 A2L zinc ribbon domain Filament PF00038.16 EMC82500.1 - 3.1e-36 125.4 37.0 3.8e-36 125.1 25.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein bZIP_2 PF07716.10 EMC82500.1 - 0.099 12.4 0.3 0.099 12.4 0.2 5.4 5 0 0 5 5 5 0 Basic region leucine zipper Phage_T7_Capsid PF05396.6 EMC82500.1 - 0.12 12.5 1.0 0.79 9.8 0.2 2.3 1 1 1 2 2 2 0 Phage T7 capsid assembly protein Myosin_tail_1 PF01576.14 EMC82500.1 - 0.16 9.6 40.1 0.28 8.8 5.2 2.1 1 1 1 2 2 2 0 Myosin tail Peptidase_C58 PF03543.9 EMC82500.1 - 1 8.8 14.8 0.23 10.9 1.1 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF3584 PF12128.3 EMC82500.1 - 1.6 5.9 33.9 2.7 5.2 23.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.1 EMC82500.1 - 2 7.5 37.9 0.012 14.8 9.5 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EMC82500.1 - 2.6 6.9 36.2 4.5 6.1 11.2 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DOR PF14839.1 EMC82500.1 - 4.6 6.9 19.7 1.4 8.6 4.7 2.3 2 0 0 2 2 2 0 DOR family DUF972 PF06156.8 EMC82500.1 - 6.1 7.2 33.9 2.9 8.3 3.5 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF972) PT PF04886.7 EMC82501.1 - 0.39 10.0 14.3 25 4.3 0.1 3.8 2 2 0 2 2 2 0 PT repeat Xlink PF00193.12 EMC82502.1 - 8.5e-50 166.8 11.4 2.9e-37 126.6 1.2 4.4 4 1 1 5 5 5 3 Extracellular link domain Lectin_C PF00059.16 EMC82502.1 - 1.4e-07 32.0 0.5 9.2e-05 23.0 0.0 3.1 3 0 0 3 3 3 1 Lectin C-type domain EGF PF00008.22 EMC82502.1 - 6.4e-07 29.2 10.0 6.4e-07 29.2 6.9 3.4 3 0 0 3 3 3 1 EGF-like domain V-set PF07686.12 EMC82502.1 - 2.3e-05 24.2 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Chordopox_A33R PF05966.7 EMC82502.1 - 0.027 13.2 0.6 0.28 9.9 0.1 2.6 3 0 0 3 3 3 0 Chordopoxvirus A33R protein I-set PF07679.11 EMC82502.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Cauli_VI PF01693.11 EMC82502.1 - 0.16 12.0 0.1 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Caulimovirus viroplasmin Myc_N PF01056.13 EMC82502.1 - 0.64 9.1 4.4 0.96 8.5 3.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Xlink PF00193.12 EMC82503.1 - 1.1e-55 185.6 1.2 4.9e-27 93.8 0.1 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 EMC82503.1 - 7.2e-15 54.8 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC82503.1 - 2.2e-08 33.8 0.0 4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82503.1 - 5.3e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC82503.1 - 0.00018 21.5 0.0 0.0079 16.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 EMC82503.1 - 0.0007 20.0 0.1 0.013 16.0 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Ammonium_transp PF00909.16 EMC82504.1 - 5.8e-27 94.1 12.6 1.1e-26 93.2 8.7 1.5 1 1 0 1 1 1 1 Ammonium Transporter Family DUF4083 PF13314.1 EMC82504.1 - 0.021 14.6 1.2 5.3 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF1003 PF06210.6 EMC82504.1 - 0.22 11.4 2.7 1.7 8.6 1.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) Daxx PF03344.10 EMC82505.1 - 0.0025 16.4 42.6 0.0036 15.8 29.5 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EMC82505.1 - 0.056 11.3 43.6 0.077 10.9 30.2 1.0 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 EMC82505.1 - 0.36 9.2 37.7 0.56 8.6 26.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 EMC82505.1 - 0.64 8.3 39.4 0.97 7.7 27.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.12 EMC82505.1 - 0.73 9.5 13.6 1.2 8.8 9.5 1.2 1 0 0 1 1 1 0 DDHD domain Caldesmon PF02029.10 EMC82505.1 - 0.74 8.1 38.5 1 7.6 26.7 1.1 1 0 0 1 1 1 0 Caldesmon Tim54 PF11711.3 EMC82505.1 - 0.94 7.9 22.7 1.4 7.4 15.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.7 EMC82505.1 - 1.7 7.8 42.0 2.4 7.3 29.1 1.1 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.5 EMC82505.1 - 2.1 7.4 29.0 3.7 6.6 20.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Na_trans_assoc PF06512.8 EMC82505.1 - 3.8 7.4 25.0 6 6.7 17.3 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF1510 PF07423.6 EMC82505.1 - 4.9 6.4 39.3 7.5 5.8 27.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 EMC82505.1 - 5.3 6.4 35.5 8.3 5.8 24.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 EMC82505.1 - 7 5.5 34.3 11 5.0 23.8 1.1 1 0 0 1 1 1 0 BUD22 GAGA_bind PF06217.7 EMC82505.1 - 9.8 6.0 10.6 19 5.1 7.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3315 PF11776.3 EMC82507.1 - 0.38 10.3 8.4 17 5.0 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF3315) Hyd_WA PF06462.7 EMC82507.1 - 1.3 8.7 16.0 15 5.3 0.1 5.1 4 1 1 5 5 5 0 Propeller 7tm_1 PF00001.16 EMC82509.1 - 5.1e-29 101.1 6.5 6.7e-29 100.8 4.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC82509.1 - 3.6e-23 81.9 3.9 3.6e-23 81.9 2.7 2.2 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 EMC82509.1 - 0.0017 17.5 5.7 0.002 17.3 3.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC82509.1 - 0.0042 16.2 6.5 0.0058 15.7 4.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Laminin_G_2 PF02210.19 EMC82510.1 - 3.3e-25 88.5 0.2 1.5e-18 67.0 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 EMC82510.1 - 6.9e-16 58.4 0.0 2.5e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain Lipase_GDSL_2 PF13472.1 EMC82511.1 - 0.00035 20.7 0.0 0.00055 20.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Laminin_G_2 PF02210.19 EMC82512.1 - 2.2e-49 166.7 0.0 8.8e-24 83.9 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 EMC82512.1 - 1.4e-28 99.5 0.0 2.4e-14 53.4 0.0 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.1 EMC82512.1 - 9.8e-06 25.8 0.0 0.0012 19.1 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Syndecan PF01034.15 EMC82512.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SET PF00856.23 EMC82513.1 - 1.3e-22 80.7 0.6 1.3e-22 80.7 0.4 2.9 2 2 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.3 EMC82513.1 - 5.9e-19 67.6 4.3 1.3e-18 66.4 3.0 1.6 1 0 0 1 1 1 1 WD repeat binding protein EZH2 Thioredoxin PF00085.15 EMC82514.1 - 1.8e-54 181.8 0.2 2e-32 110.9 0.0 2.0 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 EMC82514.1 - 4e-14 52.4 0.0 5.8e-06 26.3 0.0 3.1 2 1 1 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC82514.1 - 2.7e-13 50.1 0.1 4.6e-07 30.0 0.1 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC82514.1 - 1.2e-08 34.7 0.0 0.001 19.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EMC82514.1 - 4.2e-08 32.9 0.1 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EMC82514.1 - 3.8e-06 26.5 0.1 0.021 14.4 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 EMC82514.1 - 8.1e-05 22.6 0.7 0.67 9.9 0.1 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_9 PF14595.1 EMC82514.1 - 0.00059 19.3 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin DSBA PF01323.15 EMC82514.1 - 0.011 15.3 0.3 6.8 6.1 0.1 3.0 2 1 1 3 3 3 0 DSBA-like thioredoxin domain DUF4259 PF14078.1 EMC82514.1 - 0.11 12.9 0.1 7 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Mu-like_Com PF10122.4 EMC82514.1 - 0.27 10.3 1.4 3.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com RAMP PF04901.8 EMC82515.1 - 1.6e-44 150.2 3.3 1.8e-44 150.1 2.3 1.0 1 0 0 1 1 1 1 Receptor activity modifying family DUF1770 PF08589.5 EMC82516.1 - 0.38 11.3 5.9 0.37 11.4 2.4 2.0 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1770) Thyroglobulin_1 PF00086.13 EMC82517.1 - 7.9e-21 73.1 2.9 1.6e-20 72.2 2.0 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat C1_1 PF00130.17 EMC82519.1 - 0.0004 20.0 1.1 0.00063 19.4 0.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Phospholip_B PF04916.8 EMC82519.1 - 0.061 11.4 0.0 0.062 11.4 0.0 1.0 1 0 0 1 1 1 0 Phospholipase B Kazal_2 PF07648.10 EMC82520.1 - 5.7e-13 48.5 40.5 4.3e-06 26.5 1.6 5.7 5 0 0 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC82520.1 - 1.8e-08 34.2 45.0 0.00011 22.1 3.0 6.3 5 1 1 6 6 6 3 Kazal-type serine protease inhibitor domain Ldl_recept_a PF00057.13 EMC82520.1 - 0.0089 15.9 4.1 0.0089 15.9 2.8 6.9 5 1 1 6 6 6 2 Low-density lipoprotein receptor domain class A VWC PF00093.13 EMC82520.1 - 0.0093 16.0 4.8 0.0093 16.0 3.3 9.6 7 3 4 11 11 11 2 von Willebrand factor type C domain DNA_pol_E_B PF04042.11 EMC82520.1 - 0.018 14.2 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.20 EMC82521.1 - 1.7e-54 184.7 0.0 2.7e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82521.1 - 2.8e-35 121.6 0.0 3.8e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 EMC82521.1 - 2.8e-17 61.7 0.6 5.5e-17 60.7 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 EMC82521.1 - 9.7e-13 48.5 6.4 2.7e-12 47.1 4.4 1.8 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.18 EMC82521.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family AAA PF00004.24 EMC82522.1 - 3.1e-32 111.5 0.0 4.9e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC82522.1 - 8.3e-09 35.6 0.0 6.9e-08 32.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMC82522.1 - 9.3e-08 32.9 0.1 4.6e-07 30.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC82522.1 - 2.3e-07 31.1 0.5 4.8e-06 26.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMC82522.1 - 4e-07 30.2 0.0 7.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EMC82522.1 - 6.8e-06 25.6 0.5 0.0072 15.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.1 EMC82522.1 - 1.5e-05 24.8 0.0 6.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMC82522.1 - 3.7e-05 22.8 0.1 0.036 13.0 0.0 2.3 1 1 1 2 2 2 2 KAP family P-loop domain AAA_33 PF13671.1 EMC82522.1 - 4.3e-05 23.4 0.0 8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC82522.1 - 6e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EMC82522.1 - 8.5e-05 22.3 0.7 0.19 11.4 0.3 2.5 1 1 1 2 2 2 2 Archaeal ATPase AAA_24 PF13479.1 EMC82522.1 - 0.00016 21.3 0.0 0.00033 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMC82522.1 - 0.00021 20.7 0.0 0.00049 19.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein UPF0079 PF02367.12 EMC82522.1 - 0.00065 19.3 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EMC82522.1 - 0.0009 18.9 0.2 0.003 17.2 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 EMC82522.1 - 0.0011 18.6 0.1 0.0027 17.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EMC82522.1 - 0.0012 19.0 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.7 EMC82522.1 - 0.002 17.2 0.0 0.0047 15.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EMC82522.1 - 0.0022 17.5 0.0 0.005 16.3 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EMC82522.1 - 0.0026 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMC82522.1 - 0.0026 16.7 0.1 0.011 14.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EMC82522.1 - 0.0039 16.7 0.0 0.0076 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMC82522.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.8 2 0 0 2 2 1 1 ABC transporter PduV-EutP PF10662.4 EMC82522.1 - 0.0064 15.9 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EMC82522.1 - 0.0067 16.0 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC82522.1 - 0.0086 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 EMC82522.1 - 0.0088 15.0 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EMC82522.1 - 0.0099 15.0 0.2 0.5 9.4 0.0 2.4 1 1 1 2 2 2 1 KaiC TIP49 PF06068.8 EMC82522.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 EMC82522.1 - 0.014 14.6 0.0 0.063 12.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EMC82522.1 - 0.019 14.1 0.0 0.086 11.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zot PF05707.7 EMC82522.1 - 0.03 13.8 0.1 0.081 12.3 0.1 1.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_2 PF07724.9 EMC82522.1 - 0.033 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MMR_HSR1 PF01926.18 EMC82522.1 - 0.047 13.6 0.0 1.2 9.1 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase FMN_red PF03358.10 EMC82522.1 - 0.06 12.8 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 NADPH-dependent FMN reductase AAA_3 PF07726.6 EMC82522.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EMC82522.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EMC82522.1 - 0.073 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Miro PF08477.8 EMC82522.1 - 0.087 13.3 0.0 0.29 11.6 0.0 2.0 2 1 0 2 2 1 0 Miro-like protein CPT PF07931.7 EMC82522.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EMC82522.1 - 0.42 10.3 2.3 0.56 9.8 0.0 2.3 3 1 0 3 3 2 0 NTPase DUF3512 PF12024.3 EMC82523.1 - 3.2e-87 291.9 0.9 3.2e-87 291.9 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.20 EMC82523.1 - 3.7e-23 81.2 0.5 3.6e-22 78.0 0.1 2.6 3 0 0 3 3 3 1 Bromodomain NARP1 PF12569.3 EMC82523.1 - 1.7 7.2 15.6 3.3 6.3 10.8 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 EMC82523.1 - 2.4 7.4 16.5 0.83 8.9 9.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) p25-alpha PF05517.7 EMC82524.1 - 2.5e-57 193.4 4.3 3.1e-57 193.1 3.0 1.1 1 0 0 1 1 1 1 p25-alpha Rep_3 PF01051.16 EMC82524.1 - 0.026 14.1 0.3 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 Initiator Replication protein Drf_FH3 PF06367.11 EMC82524.1 - 0.058 12.7 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain Na_H_Exchanger PF00999.16 EMC82525.1 - 3.3e-70 236.5 46.8 1.5e-68 231.0 32.4 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DALR_1 PF05746.10 EMC82525.1 - 0.1 12.5 0.3 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 DALR anticodon binding domain LRR_8 PF13855.1 EMC82526.1 - 0.00036 20.2 3.0 0.00036 20.2 2.1 4.0 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 EMC82526.1 - 0.0009 18.8 8.9 0.25 11.0 0.3 4.1 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC82526.1 - 0.0042 16.9 8.3 5.8 7.3 0.0 5.2 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EMC82526.1 - 0.033 14.2 5.6 11 6.4 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 EMC82526.1 - 2.3 8.7 8.9 11 6.7 0.1 5.2 5 0 0 5 5 5 0 Leucine rich repeat AA_permease PF00324.16 EMC82528.1 - 1.6e-61 208.1 30.7 7.7e-37 126.7 4.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EMC82528.1 - 6.9e-20 70.9 36.3 2.6e-18 65.8 25.2 2.1 1 1 0 1 1 1 1 Amino acid permease R3H PF01424.17 EMC82529.1 - 1.2e-16 60.0 0.1 2.2e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EMC82529.1 - 2.7e-12 46.3 194.9 1.4e-05 24.8 8.0 13.7 12 3 2 14 14 14 7 NF-X1 type zinc finger Lectin_C PF00059.16 EMC82532.1 - 2.1e-13 50.7 6.5 2.1e-13 50.7 4.5 1.8 2 0 0 2 2 2 1 Lectin C-type domain Ly49 PF08391.5 EMC82532.1 - 0.0062 16.6 0.3 0.013 15.5 0.1 1.7 2 1 0 2 2 2 1 Ly49-like protein, N-terminal region Histone PF00125.19 EMC82533.1 - 3.6e-15 55.8 0.4 6e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC82533.1 - 4.9e-05 23.3 0.1 4.9e-05 23.3 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone A2M_comp PF07678.9 EMC82534.1 - 2e-80 269.5 1.0 3.1e-80 268.9 0.7 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 EMC82534.1 - 7.6e-30 103.4 0.1 1.9e-28 98.9 0.0 2.8 2 0 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 EMC82534.1 - 5.1e-28 96.4 0.1 1.3e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 EMC82534.1 - 1.4e-25 89.2 1.5 3.7e-25 87.9 1.1 1.8 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.14 EMC82534.1 - 2.2e-22 79.1 0.1 2.3e-21 75.8 0.0 2.8 3 0 0 3 3 3 1 MG2 domain Thiol-ester_cl PF10569.4 EMC82534.1 - 2e-17 62.0 1.0 4.8e-17 60.8 0.7 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 EMC82534.1 - 2e-10 41.0 1.2 9.2e-07 29.2 0.2 3.6 1 1 1 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC82534.1 - 0.0002 21.3 0.1 0.93 9.5 0.0 2.4 2 0 0 2 2 2 2 Prenyltransferase-like SVA PF05326.6 EMC82534.1 - 0.0063 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) Prenyltrans PF00432.16 EMC82534.1 - 0.058 12.9 0.2 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat A2M_comp PF07678.9 EMC82535.1 - 3.2e-85 285.2 2.4 4.6e-85 284.7 1.7 1.2 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 EMC82535.1 - 3.3e-32 111.1 0.9 1.2e-30 106.0 0.1 3.2 3 1 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 EMC82535.1 - 9.1e-28 95.6 0.0 3.5e-27 93.7 0.0 2.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 EMC82535.1 - 2e-24 85.6 0.4 5.8e-24 84.0 0.3 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.14 EMC82535.1 - 1.1e-21 76.8 0.0 4.4e-21 74.9 0.0 2.1 1 0 0 1 1 1 1 MG2 domain Thiol-ester_cl PF10569.4 EMC82535.1 - 1.7e-16 59.0 0.5 8.9e-16 56.8 0.4 2.3 2 0 0 2 2 2 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 EMC82535.1 - 2e-12 47.5 1.1 9.9e-05 22.7 0.0 3.4 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC82535.1 - 0.0007 19.5 0.1 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 Prenyltransferase-like Prenyltrans PF00432.16 EMC82535.1 - 0.011 15.2 0.1 0.32 10.5 0.0 2.9 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Utp13 PF08625.6 EMC82535.1 - 0.062 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain A2M_comp PF07678.9 EMC82536.1 - 8e-61 205.3 0.2 1.2e-60 204.8 0.1 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 EMC82536.1 - 1.3e-32 112.3 0.1 3e-28 98.3 0.0 3.0 2 0 0 2 2 2 2 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 EMC82536.1 - 2.8e-31 106.9 0.1 9e-31 105.3 0.1 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N PF01835.14 EMC82536.1 - 1.8e-19 69.8 0.1 8.7e-19 67.6 0.1 2.3 2 0 0 2 2 2 1 MG2 domain Thiol-ester_cl PF10569.4 EMC82536.1 - 2e-16 58.8 0.9 4e-16 57.9 0.6 1.5 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 EMC82536.1 - 9.1e-06 26.0 0.1 0.00041 20.7 0.0 2.5 1 1 1 2 2 2 1 Prenyltransferase-like SVA PF05326.6 EMC82536.1 - 0.00088 19.0 0.1 0.0022 17.7 0.1 1.7 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) CarboxypepD_reg PF13620.1 EMC82536.1 - 0.018 15.1 0.1 0.086 12.9 0.0 2.2 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Lsr2 PF11774.3 EMC82536.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Lsr2 A2M_comp PF07678.9 EMC82537.1 - 1.5e-60 204.4 0.1 2.4e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 EMC82537.1 - 1.4e-30 105.8 0.1 4.3e-29 101.0 0.0 2.9 3 0 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 EMC82537.1 - 2.5e-29 100.6 0.6 6.5e-29 99.3 0.1 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N PF01835.14 EMC82537.1 - 3e-21 75.4 0.0 1.1e-20 73.7 0.0 2.0 1 0 0 1 1 1 1 MG2 domain Thiol-ester_cl PF10569.4 EMC82537.1 - 1.7e-16 59.1 0.9 4.2e-16 57.8 0.6 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 EMC82537.1 - 1e-06 29.0 0.0 4.8e-05 23.7 0.0 2.5 1 1 1 2 2 2 1 Prenyltransferase-like SVA PF05326.6 EMC82537.1 - 0.013 15.3 0.0 0.093 12.5 0.0 2.4 2 0 0 2 2 2 0 Seminal vesicle autoantigen (SVA) CarboxypepD_reg PF13620.1 EMC82537.1 - 0.022 14.7 1.2 0.37 10.8 0.0 3.1 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain Man-6-P_recep PF02157.10 EMC82538.1 - 2.2e-131 436.9 0.3 2.4e-131 436.8 0.2 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EMC82538.1 - 5.9e-05 22.4 1.0 0.00053 19.3 0.7 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EMC82538.1 - 0.00018 21.3 0.3 0.026 14.2 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat A2M_comp PF07678.9 EMC82539.1 - 7.8e-69 231.6 1.2 1.4e-68 230.8 0.2 1.9 2 0 0 2 2 2 1 A-macroglobulin complement component A2M PF00207.17 EMC82539.1 - 5.3e-24 83.6 0.0 3e-23 81.2 0.0 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 EMC82539.1 - 9.5e-22 76.9 1.6 3.8e-21 75.0 1.1 2.2 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.14 EMC82539.1 - 5.6e-20 71.4 0.1 6.1e-19 68.1 0.0 2.8 2 0 0 2 2 2 1 MG2 domain A2M_N_2 PF07703.9 EMC82539.1 - 8.9e-20 70.8 0.0 2.6e-16 59.6 0.0 3.5 2 1 0 2 2 2 2 Alpha-2-macroglobulin family N-terminal region Thiol-ester_cl PF10569.4 EMC82539.1 - 6.7e-16 57.2 2.2 8.3e-16 56.9 0.1 2.4 3 0 0 3 3 3 1 Alpha-macro-globulin thiol-ester bond-forming region SVA PF05326.6 EMC82539.1 - 2.7e-14 53.0 0.0 8.6e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) Prenyltrans_2 PF13249.1 EMC82539.1 - 3.1e-10 40.4 1.6 0.00021 21.6 0.1 3.5 3 1 1 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC82539.1 - 0.0052 16.7 0.0 2.6 8.1 0.0 2.9 2 1 1 3 3 3 1 Prenyltransferase-like RimK PF08443.6 EMC82540.1 - 6.8e-43 146.3 0.0 1.1e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 EMC82540.1 - 3.1e-12 45.9 0.0 5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 EMC82540.1 - 1e-11 44.8 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMC82540.1 - 8.3e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC82540.1 - 1.7e-05 23.7 0.0 3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Synapsin_C PF02750.9 EMC82540.1 - 5.2e-05 22.4 0.0 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain ATP-grasp PF02222.17 EMC82540.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMC82540.1 - 0.0058 16.0 0.0 0.068 12.5 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.1 EMC82540.1 - 0.014 14.4 0.1 0.68 8.9 0.0 2.4 1 1 0 2 2 2 0 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.12 EMC82540.1 - 0.032 13.4 0.0 0.16 11.1 0.0 2.0 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain MAGP PF05507.6 EMC82541.1 - 3.1e-28 98.2 9.0 3.1e-28 98.2 6.3 1.3 2 0 0 2 2 2 1 Microfibril-associated glycoprotein (MAGP) Gliadin PF13016.1 EMC82541.1 - 1 9.6 7.4 0.63 10.2 1.5 2.2 1 1 1 2 2 2 0 Cys-rich Gliadin N-terminal APOBEC_N PF08210.6 EMC82542.1 - 3.7e-48 163.6 0.2 4.3e-48 163.4 0.2 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 EMC82542.1 - 1.3e-22 78.9 0.1 2.6e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain Toxin-deaminase PF14424.1 EMC82542.1 - 0.058 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RcbX PF02341.10 EMC82542.1 - 0.11 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 RbcX protein APOBEC_N PF08210.6 EMC82543.1 - 6.5e-24 84.5 0.0 7.5e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 EMC82543.1 - 2.5e-08 33.1 3.2 2.9e-08 32.9 0.0 2.5 3 0 0 3 3 3 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.17 EMC82543.1 - 0.0025 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region OTT_1508_deam PF14441.1 EMC82543.1 - 0.093 12.5 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase APOBEC_N PF08210.6 EMC82544.1 - 8.6e-22 77.6 1.1 9.3e-22 77.5 0.8 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain dCMP_cyt_deam_1 PF00383.17 EMC82544.1 - 0.0045 16.6 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FlhC PF05280.6 EMC82544.1 - 0.016 14.6 0.1 0.02 14.3 0.1 1.1 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Toxin-deaminase PF14424.1 EMC82544.1 - 0.024 14.6 0.8 0.037 13.9 0.2 1.5 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Homeobox PF00046.24 EMC82545.1 - 7e-22 76.8 4.7 1.2e-21 76.0 3.3 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC82545.1 - 0.00013 20.9 0.6 0.00028 19.8 0.4 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC82545.1 - 0.0009 18.8 0.1 0.0034 17.0 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain Pro-kuma_activ PF09286.6 EMC82545.1 - 0.0016 18.5 0.3 0.0035 17.4 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF4562 PF15123.1 EMC82545.1 - 0.07 13.0 0.4 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) Homeobox PF00046.24 EMC82546.1 - 8.6e-22 76.5 5.7 1.3e-21 75.9 3.9 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC82546.1 - 1.7e-05 23.7 0.4 3e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Pro-kuma_activ PF09286.6 EMC82546.1 - 0.0014 18.6 0.2 0.0079 16.2 0.2 1.9 1 1 1 2 2 2 1 Pro-kumamolisin, activation domain Homeobox_KN PF05920.6 EMC82546.1 - 0.0024 17.5 0.1 0.0059 16.2 0.1 1.7 1 1 0 1 1 1 1 Homeobox KN domain Cortex-I_coil PF09304.5 EMC82546.1 - 0.24 11.4 1.5 0.34 10.9 1.0 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil Sugar_tr PF00083.19 EMC82547.1 - 4.9e-157 523.1 31.9 5.6e-157 522.9 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC82547.1 - 2.4e-22 79.1 33.6 1.2e-20 73.5 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC82547.1 - 7.7e-07 27.8 35.6 7.8e-05 21.2 6.2 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein Phage_holin_2 PF04550.7 EMC82547.1 - 2.5 8.2 8.6 0.33 11.0 2.1 2.5 2 1 1 3 3 3 0 Phage holin family 2 Fork_head PF00250.13 EMC82548.1 - 1.9e-26 91.9 0.7 5.4e-26 90.4 0.0 2.1 2 0 0 2 2 2 1 Fork head domain BAF1_ABF1 PF04684.8 EMC82548.1 - 8.2 5.1 14.4 13 4.5 10.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor 7tm_1 PF00001.16 EMC82549.1 - 4e-47 160.5 17.5 1.9e-29 102.6 4.9 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82549.1 - 1.7e-05 24.0 14.0 0.0044 16.2 5.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC82549.1 - 6.3e-05 22.2 11.2 6.3e-05 22.2 7.8 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 EMC82549.1 - 0.34 9.9 15.7 2.3 7.2 9.4 2.6 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.10 EMC82549.1 - 0.35 10.6 9.3 0.07 12.8 2.7 2.1 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 60KD_IMP PF02096.15 EMC82549.1 - 6.4 6.3 6.5 1.2e+02 2.2 4.5 2.3 1 1 0 1 1 1 0 60Kd inner membrane protein DUF1681 PF07933.9 EMC82550.1 - 7.6e-64 214.1 0.0 9.6e-64 213.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Lectin_C PF00059.16 EMC82552.1 - 3.4e-15 56.5 4.1 3.4e-15 56.5 2.8 1.8 1 1 1 2 2 2 1 Lectin C-type domain ODV-E18 PF10717.4 EMC82552.1 - 0.051 13.0 1.3 0.095 12.1 0.9 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Sex_peptide PF08138.6 EMC82552.1 - 0.09 12.6 1.6 0.21 11.4 1.1 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family Herpes_UL45 PF05473.7 EMC82552.1 - 0.14 11.6 3.3 0.23 10.8 2.3 1.7 1 1 0 1 1 1 0 UL45 protein Chordopox_A13L PF05961.6 EMC82552.1 - 0.16 11.8 0.3 0.36 10.7 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein HemY_N PF07219.8 EMC82552.1 - 1 8.9 2.7 1.9 8.0 1.9 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TLV_coat PF00429.14 EMC82553.1 - 0.0044 15.5 0.0 0.0044 15.5 0.0 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) SdpI PF13630.1 EMC82553.1 - 0.13 11.9 0.2 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family PrmA PF06325.8 EMC82554.1 - 3.7e-09 36.1 0.0 6.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EMC82554.1 - 1.5e-07 31.1 0.1 3.2e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EMC82554.1 - 9.5e-07 28.0 0.2 1.2e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EMC82554.1 - 1e-06 29.3 0.0 2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC82554.1 - 1.7e-06 28.0 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC82554.1 - 6.6e-06 26.5 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMC82554.1 - 3e-05 23.7 0.1 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 EMC82554.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC82554.1 - 0.00011 21.6 0.1 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EMC82554.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_9 PF08003.6 EMC82554.1 - 0.0034 16.1 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EMC82554.1 - 0.0065 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMC82554.1 - 0.0082 15.6 0.1 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EMC82554.1 - 0.015 14.8 0.2 0.032 13.7 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMC82554.1 - 0.03 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EMC82554.1 - 0.033 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EMC82554.1 - 0.093 13.0 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PNRC PF15365.1 EMC82554.1 - 0.45 10.5 2.7 0.95 9.5 1.9 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Ras PF00071.17 EMC82555.1 - 5.7e-51 172.1 0.2 6.3e-51 171.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC82555.1 - 3e-21 76.1 0.1 4.3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC82555.1 - 4.2e-18 65.1 0.0 4.8e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC82555.1 - 1.1e-08 35.0 0.1 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC82555.1 - 3.7e-07 29.5 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC82555.1 - 3.6e-05 23.2 0.0 0.00016 21.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC82555.1 - 4.6e-05 22.7 0.0 5.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EMC82555.1 - 0.0035 17.1 0.0 0.052 13.3 0.0 2.0 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.1 EMC82555.1 - 0.022 14.9 0.0 0.077 13.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 EMC82555.1 - 0.025 13.8 0.1 0.035 13.3 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 EMC82555.1 - 0.034 14.9 0.0 0.047 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMC82555.1 - 0.045 13.9 0.0 0.072 13.2 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EMC82555.1 - 0.045 12.4 0.6 4.6 5.8 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 EMC82555.1 - 0.049 13.5 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMC82555.1 - 0.058 12.8 0.1 1.5 8.2 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EMC82555.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 EMC82555.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin MobB PF03205.9 EMC82555.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_7 PF13499.1 EMC82556.1 - 1.9e-09 37.5 0.1 3.5e-06 27.0 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC82556.1 - 1.1e-08 33.7 0.1 0.00072 18.6 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC82556.1 - 4.7e-08 32.2 0.1 0.013 15.3 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC82556.1 - 7.8e-07 28.6 0.1 6.6e-06 25.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC82556.1 - 2.1e-06 26.8 0.1 0.029 13.7 0.0 3.4 2 0 0 2 2 2 2 EF hand Plasmod_Pvs28 PF06247.6 EMC82556.1 - 0.0098 15.4 0.4 0.0098 15.4 0.3 2.3 2 1 0 3 3 3 1 Plasmodium ookinete surface protein Pvs28 TroA PF01297.12 EMC82556.1 - 0.61 9.2 3.0 0.64 9.2 1.2 1.5 1 1 0 1 1 1 0 Periplasmic solute binding protein family C_GCAxxG_C_C PF09719.5 EMC82556.1 - 2 8.2 6.6 5.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) GAGA_bind PF06217.7 EMC82556.1 - 9.9 6.0 9.2 15 5.4 6.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PARP PF00644.15 EMC82557.1 - 2.8e-45 154.2 0.0 4.6e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 EMC82557.1 - 6.6e-08 31.8 0.1 1.4e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 WWE domain Tetraspannin PF00335.15 EMC82558.1 - 7.8e-56 188.8 19.6 8.9e-56 188.6 13.6 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 EMC82558.1 - 0.17 11.5 12.4 0.1 12.2 3.4 2.7 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction ODV-E18 PF10717.4 EMC82558.1 - 0.27 10.6 1.5 0.43 10.0 0.2 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.6 EMC82558.1 - 0.59 9.5 3.6 0.33 10.3 0.5 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3592 PF12158.3 EMC82558.1 - 7.3 6.3 8.7 16 5.2 4.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) TEA PF01285.13 EMC82559.1 - 1.3e-175 584.7 0.1 1.6e-175 584.4 0.1 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EMC82559.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Tub PF01167.13 EMC82560.1 - 4.1e-116 386.2 0.0 6.6e-116 385.5 0.0 1.3 1 0 0 1 1 1 1 Tub family DUF2890 PF11081.3 EMC82560.1 - 0.35 10.9 5.6 0.66 10.0 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RHINO PF15319.1 EMC82561.1 - 7e-69 232.2 9.1 8e-69 232.0 6.3 1.0 1 0 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein Fork_head PF00250.13 EMC82562.1 - 2.1e-27 94.9 0.2 4.4e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 Fork head domain TSA PF03249.8 EMC82562.1 - 0.15 10.5 0.2 0.22 9.9 0.2 1.1 1 0 0 1 1 1 0 Type specific antigen Tim54 PF11711.3 EMC82562.1 - 3 6.3 5.9 0.3 9.6 0.3 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Asp_protease PF09668.5 EMC82563.1 - 2.7e-09 36.6 0.0 4.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EMC82563.1 - 0.005 16.6 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DMAP_binding PF06464.6 EMC82563.1 - 0.091 13.3 0.4 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 DMAP1-binding Domain BBS2_Mid PF14783.1 EMC82565.1 - 1.3e-15 57.1 0.1 0.00051 19.7 0.0 3.8 3 1 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 EMC82565.1 - 3.1e-08 33.0 1.8 0.00096 18.7 0.1 3.8 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 EMC82565.1 - 5.8e-06 26.5 4.4 0.18 12.1 0.2 3.6 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PHTB1_N PF14727.1 EMC82565.1 - 0.016 14.2 0.0 0.67 8.8 0.0 2.6 2 1 1 3 3 3 0 PTHB1 N-terminus DUF4399 PF14347.1 EMC82565.1 - 0.098 12.6 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) BBS2_C PF14782.1 EMC82565.1 - 0.2 10.1 0.0 14 4.0 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal FKBP_C PF00254.23 EMC82566.1 - 1.3e-46 156.5 0.1 5.3e-31 106.4 0.0 2.5 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.23 EMC82566.1 - 9.3e-19 66.1 10.8 2.5e-09 36.3 1.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMC82566.1 - 1.1e-18 66.5 5.0 3.4e-14 52.2 1.7 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC82566.1 - 9.3e-15 53.2 14.4 3.4e-06 26.5 0.9 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC82566.1 - 2.3e-10 39.4 7.4 4.5e-05 22.9 0.6 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC82566.1 - 2.8e-09 37.4 0.5 0.0088 16.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC82566.1 - 7.3e-08 32.3 3.1 0.0034 17.7 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC82566.1 - 1e-07 32.1 3.5 8.3e-05 22.8 0.3 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC82566.1 - 1.4e-06 28.1 12.1 4.8e-05 23.2 1.4 3.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC82566.1 - 2.4e-06 27.6 0.2 0.0059 17.1 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC82566.1 - 0.00015 21.3 3.8 0.039 13.7 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC82566.1 - 0.00051 19.8 0.2 0.00051 19.8 0.2 3.1 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EMC82566.1 - 0.00091 19.0 0.1 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC82566.1 - 0.0033 17.4 5.4 0.037 14.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC82566.1 - 0.0096 16.0 7.3 0.028 14.5 3.8 2.3 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 EMC82566.1 - 0.011 15.5 0.5 0.024 14.4 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) OmpH PF03938.9 EMC82566.1 - 0.48 10.3 7.1 1.1 9.2 4.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lectin_C PF00059.16 EMC82567.1 - 1.5e-17 64.1 1.4 2e-17 63.7 1.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 EMC82567.1 - 0.021 14.2 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 UL45 protein Aldo_ket_red PF00248.16 EMC82568.1 - 7.3e-53 179.2 0.0 8.4e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1456 PF07308.8 EMC82568.1 - 0.08 12.9 0.0 0.53 10.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) DUF1187 PF06688.6 EMC82568.1 - 0.091 12.8 4.5 29 4.8 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1187) Retinal PF15449.1 EMC82569.1 - 0.59 7.7 9.1 0.65 7.5 6.3 1.1 1 0 0 1 1 1 0 Retinal protein His_Phos_1 PF00300.17 EMC82570.1 - 1.3e-43 148.8 0.0 1.6e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF134 PF02001.11 EMC82571.1 - 0.00042 20.1 8.1 15 5.5 0.1 5.9 1 1 1 2 2 2 1 Protein of unknown function DUF134 DUF1884 PF08967.5 EMC82571.1 - 0.17 11.9 15.3 53 3.9 0.6 6.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1884) Bacillus_HBL PF05791.6 EMC82571.1 - 1.1 8.6 13.7 16 4.8 0.6 4.8 1 1 4 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) EF-hand_1 PF00036.27 EMC82572.1 - 2.7e-14 51.2 3.0 2.1e-05 23.4 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC82572.1 - 2.9e-12 45.3 6.0 0.00012 21.7 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EMC82572.1 - 5.7e-11 42.3 4.2 3.3e-05 23.9 0.6 3.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC82572.1 - 1.2e-08 33.8 0.0 0.0026 17.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 EMC82572.1 - 4.9e-08 32.5 0.5 0.016 14.8 0.0 4.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EMC82572.1 - 0.0034 16.9 0.2 1.5 8.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC82572.1 - 0.0074 16.3 3.5 0.43 10.6 2.0 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region PDZ PF00595.19 EMC82573.1 - 8e-11 41.9 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PB1 PF00564.19 EMC82573.1 - 8.1e-10 38.2 0.0 2e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 PB1 domain PDZ_2 PF13180.1 EMC82573.1 - 0.03 14.2 0.1 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain BLOC1_2 PF10046.4 EMC82574.1 - 0.036 14.1 0.2 0.3 11.2 0.0 2.0 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.8 EMC82574.1 - 0.047 12.6 0.3 0.065 12.1 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1098 PF06497.6 EMC82574.1 - 0.064 13.3 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) Med4 PF10018.4 EMC82574.1 - 0.13 11.6 0.0 0.47 9.8 0.0 1.7 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CAP PF00188.21 EMC82575.1 - 3.8e-22 79.0 0.6 4.6e-22 78.8 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ifi-6-16 PF06140.8 EMC82576.1 - 7.1e-24 83.4 21.9 1.7e-13 50.1 3.9 2.0 1 1 1 2 2 2 2 Interferon-induced 6-16 family SMP PF04927.7 EMC82576.1 - 0.063 13.2 3.4 0.4 10.6 0.2 2.4 2 1 1 3 3 3 0 Seed maturation protein SoxE PF06525.6 EMC82576.1 - 0.18 11.0 2.6 0.25 10.5 0.4 1.9 2 0 0 2 2 2 0 Sulfocyanin (SoxE) Arabino_trans_C PF14896.1 EMC82576.1 - 0.27 9.7 1.4 0.36 9.3 0.8 1.3 1 1 0 1 1 1 0 EmbC C-terminal domain Glycos_transf_1 PF00534.15 EMC82577.1 - 2.3e-37 128.0 0.0 3.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC82577.1 - 1.8e-09 37.8 0.0 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMC82577.1 - 3.8e-06 27.0 0.0 9.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMC82577.1 - 0.0014 18.8 0.3 0.0029 17.7 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Sec61_beta PF03911.11 EMC82578.1 - 1e-21 76.4 0.0 1.3e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family zf-C4 PF00105.13 EMC82579.1 - 3.1e-31 107.3 18.2 5.5e-31 106.5 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC82579.1 - 3.7e-17 62.1 0.0 7.8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C9orf72-like PF15019.1 EMC82579.1 - 0.01 15.0 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family BAAT_C PF08840.6 EMC82580.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SNARE PF05739.14 EMC82581.1 - 1.1e-10 41.0 1.7 1.2e-10 40.9 0.1 1.8 2 0 0 2 2 2 1 SNARE domain Gly-zipper_OmpA PF13436.1 EMC82581.1 - 0.0096 15.5 3.7 0.016 14.8 2.5 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain RseC_MucC PF04246.7 EMC82581.1 - 0.017 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Vac_Fusion PF02346.11 EMC82581.1 - 0.085 12.2 0.4 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF1469 PF07332.6 EMC82581.1 - 0.13 11.9 4.6 0.17 11.5 2.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) TraT PF05818.7 EMC82581.1 - 0.43 9.9 3.1 0.69 9.2 2.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein HlyE PF06109.8 EMC82581.1 - 0.5 9.3 4.2 2.6 6.9 0.1 2.2 1 1 1 2 2 2 0 Haemolysin E (HlyE) Gly-zipper_YMGG PF13441.1 EMC82581.1 - 0.96 9.0 15.1 1.7 8.2 10.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Thioredoxin_6 PF13848.1 EMC82582.1 - 4.5e-47 160.2 0.4 3.5e-42 144.2 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 EMC82582.1 - 1.6e-21 75.8 0.0 4e-21 74.6 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.12 EMC82582.1 - 5.3e-09 35.3 0.1 6.6e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 EMC82582.1 - 9.2e-05 22.6 0.0 0.00039 20.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC82582.1 - 0.00086 19.3 0.8 0.0054 16.8 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 EMC82582.1 - 0.0012 18.7 0.0 0.0039 17.0 0.0 1.8 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EMC82582.1 - 0.0092 15.9 0.1 0.16 12.0 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like MBT PF02820.13 EMC82584.1 - 9.8e-24 83.0 0.5 2.9e-23 81.5 0.1 2.0 2 0 0 2 2 2 1 mbt repeat DUF3661 PF12400.3 EMC82585.1 - 1.5e-36 125.3 10.6 2.2e-36 124.7 7.3 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein Vpu PF00558.14 EMC82585.1 - 0.21 11.1 2.0 0.29 10.7 0.0 2.3 3 0 0 3 3 3 0 Vpu protein TB2_DP1_HVA22 PF03134.14 EMC82585.1 - 0.29 10.9 5.7 0.066 12.9 0.7 2.3 1 1 2 3 3 3 0 TB2/DP1, HVA22 family ITI_HC_C PF06668.7 EMC82586.1 - 4.2e-73 244.7 0.6 8.7e-73 243.7 0.4 1.6 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.5 EMC82586.1 - 1.3e-41 140.9 2.7 2.2e-41 140.2 0.9 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EMC82586.1 - 7e-22 77.9 0.3 1.5e-21 76.9 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC82586.1 - 6.9e-19 68.0 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC82586.1 - 3.4e-16 59.8 0.1 5.7e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMC82586.1 - 8.8e-05 21.7 0.0 0.00021 20.4 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 EMC82586.1 - 0.00028 20.7 0.3 0.00056 19.7 0.2 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2828 PF11443.3 EMC82586.1 - 0.0034 15.6 0.1 0.0052 15.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF2201 PF09967.4 EMC82586.1 - 0.0056 16.6 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 VWA-like domain (DUF2201) ATP-synt PF00231.14 EMC82587.1 - 4.8e-76 255.8 2.2 5.5e-76 255.6 1.5 1.0 1 0 0 1 1 1 1 ATP synthase ACT_4 PF13291.1 EMC82587.1 - 0.1 12.9 1.6 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 ACT domain PHD PF00628.24 EMC82588.1 - 1e-11 44.3 7.4 2.5e-11 43.0 5.2 1.7 1 0 0 1 1 1 1 PHD-finger Ycf1 PF05758.7 EMC82588.1 - 0.00046 18.0 1.1 0.00046 18.0 0.8 2.5 2 1 0 2 2 2 1 Ycf1 PHD_2 PF13831.1 EMC82588.1 - 0.0011 18.2 2.3 0.0011 18.2 1.6 2.2 2 0 0 2 2 2 1 PHD-finger GATA PF00320.22 EMC82589.1 - 4.4e-31 105.9 19.7 1.2e-15 56.4 3.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EMC82589.1 - 2e-05 23.7 7.1 0.029 13.6 0.8 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.5 EMC82589.1 - 0.043 13.7 6.3 3.7 7.5 0.7 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Prim_Zn_Ribbon PF08273.7 EMC82589.1 - 0.18 11.9 11.0 0.1 12.7 1.5 2.8 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase eIF-5_eIF-2B PF01873.12 EMC82589.1 - 0.18 11.4 5.2 4.2 7.0 0.6 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 EMC82589.1 - 0.89 9.4 12.4 12 5.8 6.4 2.9 1 1 2 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EMC82589.1 - 1.8 8.3 13.5 0.74 9.6 2.6 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EMC82589.1 - 3.5 7.3 11.7 2 8.1 0.8 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Elf1 PF05129.8 EMC82589.1 - 7.5 6.3 8.2 9.1 6.0 0.2 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Cytochrom_c3_2 PF14537.1 EMC82589.1 - 7.6 6.9 12.2 16 5.9 0.3 3.0 2 1 0 3 3 2 0 Cytochrome c3 Zn-ribbon_8 PF09723.5 EMC82589.1 - 9.9 6.2 8.9 2.1 8.3 0.1 3.3 3 1 0 4 4 3 0 Zinc ribbon domain GETHR PF05671.6 EMC82590.1 - 3.5e-05 22.8 263.8 4.3 6.5 13.9 12.4 1 1 9 10 10 10 3 GETHR pentapeptide repeat (5 copies) Lig_chan PF00060.21 EMC82591.1 - 3.7e-45 153.2 0.3 6e-45 152.5 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 EMC82591.1 - 1.7e-27 96.1 0.0 2.8e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 EMC82591.1 - 2.2e-23 82.0 0.1 5e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 EMC82591.1 - 2e-13 49.9 0.0 3.9e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region DUF1469 PF07332.6 EMC82591.1 - 0.0087 15.7 0.2 0.0087 15.7 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1469) NADH-u_ox-rdase PF10785.4 EMC82591.1 - 0.019 15.2 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ANF_receptor PF01094.23 EMC82592.1 - 7.3e-07 28.2 0.0 9.8e-07 27.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region WAPL PF07814.8 EMC82593.1 - 7e-148 492.1 7.6 1.3e-147 491.3 5.3 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin 7tm_1 PF00001.16 EMC82594.1 - 6e-59 199.2 17.5 7.8e-59 198.8 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82594.1 - 1.2e-13 50.8 17.1 1.6e-13 50.4 11.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC82594.1 - 8.6e-08 31.6 18.6 1.3e-07 31.0 12.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 EMC82594.1 - 9.4e-05 21.6 9.9 0.00015 21.0 6.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Git3 PF11710.3 EMC82594.1 - 0.034 13.7 13.2 0.071 12.6 9.1 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF2852 PF11014.3 EMC82594.1 - 1.3 8.9 4.3 16 5.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) LIM PF00412.17 EMC82595.1 - 4.1e-37 126.0 31.2 2.1e-13 50.1 2.9 3.3 3 0 0 3 3 3 3 LIM domain RWD PF05773.17 EMC82596.1 - 1.7e-24 85.9 0.0 3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EMC82596.1 - 1.4e-10 40.8 3.6 1.4e-10 40.8 2.5 3.7 2 1 1 3 3 3 1 IBR domain zf-RING_5 PF14634.1 EMC82596.1 - 0.00023 20.8 15.5 0.00023 20.8 10.7 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC82596.1 - 0.0012 18.6 11.6 0.0012 18.6 8.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC82596.1 - 0.012 15.5 13.8 0.012 15.5 9.6 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) COLFI PF01410.13 EMC82599.1 - 5.3e-15 55.4 0.0 5.9e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Ras PF00071.17 EMC82600.1 - 8.3e-49 165.0 0.1 9.2e-49 164.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC82600.1 - 5.7e-22 78.4 0.0 6.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC82600.1 - 8.8e-13 47.8 0.0 1.2e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC82600.1 - 1.9e-05 23.9 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC82600.1 - 2.2e-05 24.3 0.1 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC82600.1 - 4.6e-05 22.9 0.0 0.00053 19.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC82600.1 - 0.002 17.4 0.0 0.003 16.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMC82600.1 - 0.0058 16.7 0.1 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC82600.1 - 0.012 15.5 0.1 0.028 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EMC82600.1 - 0.014 14.5 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 KaiC Septin PF00735.13 EMC82600.1 - 0.025 13.5 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Septin Arch_ATPase PF01637.13 EMC82600.1 - 0.026 14.2 0.0 0.028 14.1 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EMC82600.1 - 0.026 14.7 0.1 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMC82600.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EMC82600.1 - 0.031 13.8 0.0 3.5 7.0 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 EMC82600.1 - 0.049 12.2 0.0 0.076 11.6 0.0 1.4 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 EMC82600.1 - 0.049 13.1 0.0 0.068 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EMC82600.1 - 0.05 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 EMC82600.1 - 0.061 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NACHT PF05729.7 EMC82600.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EMC82600.1 - 0.1 11.5 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) G-alpha PF00503.15 EMC82600.1 - 0.2 10.2 0.7 1 7.9 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Stanniocalcin PF03298.8 EMC82601.1 - 5.1e-84 280.4 12.6 6.7e-84 280.0 8.8 1.1 1 0 0 1 1 1 1 Stanniocalcin family Homeobox PF00046.24 EMC82602.1 - 9.1e-21 73.2 4.2 9.1e-21 73.2 2.9 1.7 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 EMC82602.1 - 0.087 11.8 0.3 0.19 10.8 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sec20 PF03908.8 EMC82603.1 - 5.2e-33 112.6 7.9 5.7e-33 112.4 3.1 2.1 2 0 0 2 2 2 1 Sec20 DUF2777 PF10949.3 EMC82603.1 - 0.0023 17.6 1.9 0.0031 17.2 1.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2777) WD-3 PF09765.4 EMC82603.1 - 0.06 12.6 4.3 0.08 12.2 3.0 1.1 1 0 0 1 1 1 0 WD-repeat region DUF4290 PF14123.1 EMC82603.1 - 0.092 11.9 2.1 0.1 11.7 0.3 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4290) ThiG PF05690.9 EMC82603.1 - 0.12 11.3 4.0 0.49 9.4 0.7 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG IL6 PF00489.12 EMC82603.1 - 0.19 11.3 4.4 0.75 9.3 0.2 2.2 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Sec16 PF12932.2 EMC82603.1 - 0.25 11.3 2.6 0.52 10.2 0.1 2.3 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region DUF1664 PF07889.7 EMC82603.1 - 0.35 10.6 7.3 3.5 7.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4337 PF14235.1 EMC82603.1 - 0.47 10.2 18.0 1.9 8.2 3.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) 7tm_6 PF02949.15 EMC82603.1 - 0.48 9.2 6.3 0.073 11.9 2.0 1.6 2 1 0 2 2 2 0 7tm Odorant receptor Cep57_MT_bd PF06657.8 EMC82603.1 - 0.6 10.0 9.9 0.14 12.1 1.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Mnd1 PF03962.10 EMC82603.1 - 0.61 9.7 15.8 1.1 8.9 11.0 1.4 1 1 0 1 1 1 0 Mnd1 family Tombus_P33 PF08500.5 EMC82603.1 - 0.72 9.5 3.6 0.48 10.1 0.6 1.9 1 1 0 2 2 2 0 Tombusvirus p33 His_kinase PF06580.8 EMC82603.1 - 0.76 9.7 4.0 0.28 11.1 0.5 1.9 2 0 0 2 2 2 0 Histidine kinase DUF1706 PF08020.6 EMC82603.1 - 0.93 8.9 7.5 2.7 7.4 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1706) Folliculin PF11704.3 EMC82603.1 - 1.4 8.4 11.2 0.3 10.6 1.6 2.1 1 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF972 PF06156.8 EMC82603.1 - 1.5 9.1 15.2 0.74 10.1 2.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) ACCA PF03255.9 EMC82603.1 - 1.8 8.1 8.0 0.33 10.5 1.6 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HlyD PF00529.15 EMC82603.1 - 2.2 7.5 14.0 2.7 7.2 9.7 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF572 PF04502.8 EMC82603.1 - 2.7 7.1 15.7 3.3 6.8 10.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2924 PF11149.3 EMC82603.1 - 3 7.8 10.3 34 4.4 7.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Med9 PF07544.8 EMC82603.1 - 3.2 7.5 9.4 5.5 6.8 0.1 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 YtxH PF12732.2 EMC82603.1 - 3.3 8.1 8.9 14 6.1 1.4 2.5 2 0 0 2 2 2 0 YtxH-like protein Syntaxin PF00804.20 EMC82603.1 - 4 7.6 17.2 0.25 11.5 2.3 2.3 1 1 1 2 2 2 0 Syntaxin DUF3807 PF12720.2 EMC82603.1 - 4.4 7.4 10.1 7.1 6.7 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) SPARC_Ca_bdg PF10591.4 EMC82603.1 - 4.4 7.3 7.5 1 9.4 0.8 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Syntaxin-6_N PF09177.6 EMC82603.1 - 4.5 7.7 11.5 6.1 7.3 2.0 2.3 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Muted PF14942.1 EMC82603.1 - 5.8 6.7 16.8 1.1 9.0 1.8 2.2 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Elongin_A PF06881.6 EMC82603.1 - 6.3 7.2 9.7 3.1 8.2 4.5 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A bZIP_1 PF00170.16 EMC82604.1 - 0.00057 19.7 3.4 0.00057 19.7 2.4 3.0 3 0 0 3 3 3 1 bZIP transcription factor Astro_capsid PF03115.9 EMC82604.1 - 0.0061 14.8 3.0 0.0088 14.3 2.1 1.2 1 0 0 1 1 1 1 Astrovirus capsid protein precursor bZIP_2 PF07716.10 EMC82604.1 - 0.011 15.5 1.9 0.011 15.5 1.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper TFIIA PF03153.8 EMC82604.1 - 0.17 11.7 15.8 0.36 10.6 10.9 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATP_synt_H PF05493.8 EMC82605.1 - 6.2e-08 32.5 0.2 7.3e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit H KOW PF00467.24 EMC82606.1 - 4.3e-08 32.5 5.9 1.8e-07 30.6 4.1 2.2 1 1 0 1 1 1 1 KOW motif PilP PF04351.8 EMC82606.1 - 0.16 11.9 2.1 0.26 11.1 1.5 1.6 1 1 0 1 1 1 0 Pilus assembly protein, PilP Toxin_56 PF15534.1 EMC82606.1 - 0.49 10.9 5.7 0.21 12.0 0.6 2.2 2 1 0 2 2 2 0 Putative toxin 56 COPIIcoated_ERV PF07970.7 EMC82607.1 - 9.4e-38 130.0 0.1 1.7e-37 129.1 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMC82607.1 - 1.5e-24 85.7 1.1 2.9e-24 84.8 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Neuralized PF07177.7 EMC82608.1 - 6.8e-41 137.9 0.3 1.3e-24 85.7 0.1 2.5 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.1 EMC82608.1 - 6.3e-13 48.1 13.2 1.4e-12 47.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC82608.1 - 2e-05 24.5 15.9 5.1e-05 23.2 11.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC82608.1 - 0.024 14.3 15.0 0.059 13.1 10.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain ubiquitin PF00240.18 EMC82610.1 - 3.3e-11 42.4 0.0 5.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC82610.1 - 4.8e-05 22.9 0.0 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Duffy_binding PF05424.6 EMC82610.1 - 0.095 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Duffy binding domain 7tm_1 PF00001.16 EMC82611.1 - 2.2e-81 272.7 10.9 2.9e-81 272.4 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82611.1 - 8.4e-16 57.9 14.7 1.2e-15 57.4 10.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC82611.1 - 4.1e-09 35.9 12.0 4.1e-09 35.9 8.3 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2434 PF10361.4 EMC82611.1 - 0.56 9.2 10.6 5 6.1 7.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2434) TPR_12 PF13424.1 EMC82612.1 - 1.6e-16 59.9 47.1 8e-06 25.7 5.4 8.1 5 2 2 8 8 8 5 Tetratricopeptide repeat SH3_2 PF07653.12 EMC82612.1 - 1.3e-09 37.4 0.0 0.00016 21.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain TPR_11 PF13414.1 EMC82612.1 - 5.8e-09 35.4 36.5 0.0029 17.2 3.2 7.1 5 1 1 6 6 6 5 TPR repeat SH3_9 PF14604.1 EMC82612.1 - 6.8e-09 35.1 0.1 6.9e-06 25.5 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SNAP PF14938.1 EMC82612.1 - 3.5e-06 26.3 3.6 1.7e-05 24.1 0.3 3.1 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP SH3_1 PF00018.23 EMC82612.1 - 3.3e-05 23.1 0.2 0.043 13.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain TPR_1 PF00515.23 EMC82612.1 - 4.7e-05 22.8 31.7 0.00014 21.3 0.0 8.6 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC82612.1 - 0.0029 17.2 21.8 3.2 7.7 0.0 9.1 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC82612.1 - 0.0081 15.9 0.1 0.0081 15.9 0.0 9.8 10 1 1 11 11 11 2 Tetratricopeptide repeat DUF2225 PF09986.4 EMC82612.1 - 0.031 13.7 6.2 0.55 9.6 0.4 4.0 3 2 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.1 EMC82612.1 - 1 9.3 19.8 8.1 6.5 0.1 8.0 7 1 1 9 9 9 0 Tetratricopeptide repeat PH PF00169.24 EMC82613.1 - 1.6e-16 60.3 0.0 1.5e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC82613.1 - 0.00035 20.7 0.1 0.34 11.1 0.0 2.9 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 EMC82613.1 - 0.053 13.6 0.1 15 5.7 0.0 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4300 PF14133.1 EMC82613.1 - 0.12 11.6 0.0 0.78 8.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) Sec7_N PF12783.2 EMC82613.1 - 0.56 9.6 3.7 5.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal GrpE PF01025.14 EMC82614.1 - 5.5e-43 146.3 0.0 6.5e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 GrpE Laminin_I PF06008.9 EMC82614.1 - 0.00047 19.5 0.0 0.00061 19.1 0.0 1.1 1 0 0 1 1 1 1 Laminin Domain I DUF2408 PF10303.4 EMC82614.1 - 0.0055 16.8 0.3 0.0078 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) DUF4525 PF15027.1 EMC82614.1 - 0.062 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Prenylcys_lyase PF07156.9 EMC82615.1 - 1.4e-143 478.3 0.0 1.6e-143 478.0 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase ADH_zinc_N PF00107.21 EMC82615.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IL17 PF06083.6 EMC82616.1 - 2.1e-30 104.5 1.4 3.4e-30 103.9 1.0 1.3 1 0 0 1 1 1 1 Interleukin-17 Pkinase PF00069.20 EMC82617.1 - 1.4e-36 126.0 0.0 1.7e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82617.1 - 7e-12 44.9 0.0 2.5e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMC82617.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RhoGEF PF00621.15 EMC82618.1 - 3.5e-39 134.5 0.9 3.5e-39 134.5 0.6 1.4 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EMC82618.1 - 8.3e-08 32.0 1.1 2.3e-06 27.3 0.0 2.7 2 1 1 3 3 3 1 BAR domain UvrB PF12344.3 EMC82618.1 - 0.079 12.5 0.6 0.17 11.4 0.4 1.5 1 0 0 1 1 1 0 Ultra-violet resistance protein B SH3_2 PF07653.12 EMC82619.1 - 7.3e-06 25.3 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain LAP2alpha PF11560.3 EMC82619.1 - 0.017 14.2 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha SH3_9 PF14604.1 EMC82619.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain BNIP3 PF06553.7 EMC82623.1 - 1.3e-45 155.1 0.1 1.5e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 BNIP3 PWWP PF00855.12 EMC82626.1 - 2.9e-18 65.8 0.7 7.5e-18 64.5 0.5 1.7 1 0 0 1 1 1 1 PWWP domain DUF4614 PF15391.1 EMC82626.1 - 0.071 12.8 3.1 2.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Planc_extracel PF07595.7 EMC82626.1 - 0.24 11.1 4.1 9.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Planctomycete extracellular TLE_N PF03920.10 EMC82627.1 - 4.4e-66 220.8 5.9 5.8e-66 220.4 4.1 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HALZ PF02183.13 EMC82627.1 - 0.032 13.9 0.7 0.066 12.9 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper ELM2 PF01448.19 EMC82629.1 - 7.3e-14 52.1 0.1 2.5e-13 50.4 0.1 2.0 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.26 EMC82629.1 - 3e-05 23.9 0.3 6.2e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2002 PF09400.5 EMC82629.1 - 0.087 12.5 0.2 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) MFS_1 PF07690.11 EMC82630.1 - 1.5e-22 79.8 26.2 6.4e-19 67.8 14.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC82630.1 - 0.0028 16.2 11.4 0.0094 14.5 7.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter UQ_con PF00179.21 EMC82631.1 - 5e-46 155.6 0.0 6.5e-46 155.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC82631.1 - 0.0044 16.7 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B Ig_2 PF13895.1 EMC82632.1 - 1.2e-13 50.9 1.8 1.7e-07 31.2 0.1 3.3 2 1 1 3 3 3 3 Immunoglobulin domain I-set PF07679.11 EMC82632.1 - 1.7e-13 50.2 0.3 1.1e-08 34.7 0.0 3.6 3 1 1 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.12 EMC82632.1 - 8.7e-10 38.5 0.4 2.8e-05 23.9 0.1 3.5 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC82632.1 - 8.5e-09 35.8 6.5 0.0019 18.6 0.8 3.8 4 1 0 4 4 4 2 Immunoglobulin domain ig PF00047.20 EMC82632.1 - 0.00019 21.4 4.2 0.44 10.6 0.0 3.9 3 2 1 4 4 4 2 Immunoglobulin domain Orthoreo_P10 PF07204.6 EMC82632.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Ion_trans_N PF08412.5 EMC82633.1 - 5.8e-30 102.4 0.1 1.2e-29 101.3 0.1 1.6 1 0 0 1 1 1 1 Ion transport protein N-terminal cNMP_binding PF00027.24 EMC82633.1 - 4.9e-21 74.3 0.0 8.7e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 EMC82633.1 - 1e-09 37.9 2.4 1e-09 37.9 1.7 2.7 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.11 EMC82633.1 - 0.002 17.7 0.2 0.002 17.7 0.1 2.3 3 0 0 3 3 3 1 Ion channel RNA_pol PF00940.14 EMC82634.1 - 1.3e-148 494.7 0.0 1.9e-148 494.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EMC82634.1 - 6.6e-46 157.0 0.0 2.7e-45 155.0 0.0 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 EMC82634.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 EMC82634.1 - 0.00097 19.2 0.0 0.0041 17.2 0.0 2.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.15 EMC82634.1 - 0.078 12.9 0.1 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 PPR repeat zf-RING_2 PF13639.1 EMC82635.1 - 5.3e-16 58.1 7.5 5.3e-16 58.1 5.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMC82635.1 - 3.7e-08 33.3 6.3 1e-07 31.9 4.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC82635.1 - 4.6e-08 32.9 6.5 4.6e-08 32.9 4.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC82635.1 - 6.3e-08 32.2 5.2 6.3e-08 32.2 3.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC82635.1 - 9.7e-08 31.5 2.6 9.7e-08 31.5 1.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC82635.1 - 4.5e-07 29.4 5.9 4.5e-07 29.4 4.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC82635.1 - 3.7e-05 23.4 3.7 0.0001 22.0 2.5 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 EMC82635.1 - 0.0015 18.4 0.5 0.0015 18.4 0.4 3.1 3 0 0 3 3 3 1 zinc-finger zf-RING_UBOX PF13445.1 EMC82635.1 - 0.0033 17.0 6.2 0.017 14.8 0.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EMC82635.1 - 0.018 14.5 3.4 0.041 13.3 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Opy2 PF09463.5 EMC82635.1 - 0.04 14.0 3.6 9 6.4 0.1 3.3 3 0 0 3 3 3 0 Opy2 protein Vps39_2 PF10367.4 EMC82635.1 - 0.091 12.9 1.0 15 5.7 0.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rad50_zn_hook PF04423.9 EMC82635.1 - 0.27 10.7 0.1 0.27 10.7 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 EMC82635.1 - 0.86 9.2 11.2 2.1 7.9 0.2 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EMC82635.1 - 1.3 9.1 5.1 2.6 8.1 3.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EMC82635.1 - 2.5 8.1 8.4 49 3.9 5.8 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EMC82635.1 - 3.1 7.5 10.6 3.5 7.3 4.2 2.5 2 0 0 2 2 2 0 PHD-finger TF_Zn_Ribbon PF08271.7 EMC82635.1 - 4.3 6.7 7.4 13 5.1 0.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding DUF3678 PF12435.3 EMC82635.1 - 5.3 6.6 14.9 0.25 10.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) zf-C3HC4_4 PF15227.1 EMC82635.1 - 8.3 6.3 10.7 9.6 6.1 5.0 2.8 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Kazal_2 PF07648.10 EMC82636.1 - 3.5e-17 62.0 11.9 8.8e-10 38.3 1.9 4.2 4 1 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC82636.1 - 8.9e-11 41.6 34.4 2.8e-07 30.4 2.7 4.0 3 2 1 4 4 4 2 Kazal-type serine protease inhibitor domain FOLN PF09289.5 EMC82636.1 - 0.00093 18.9 10.0 0.00093 18.9 6.9 3.5 3 0 0 3 3 3 1 Follistatin/Osteonectin-like EGF domain Trypsin PF00089.21 EMC82637.1 - 8.1e-48 162.8 0.0 9e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC82637.1 - 4.5e-05 22.8 0.0 6.1e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC82637.1 - 4.7e-05 23.3 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain AKAP2_C PF15304.1 EMC82638.1 - 9.4e-17 61.6 3.6 9.4e-17 61.6 2.5 3.1 2 1 0 3 3 3 2 A-kinase anchor protein 2 C-terminus VASP_tetra PF08776.6 EMC82639.1 - 0.06 12.6 0.2 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain RRM_5 PF13893.1 EMC82640.1 - 3.6e-48 161.2 1.8 1.2e-14 53.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82640.1 - 1e-37 127.9 0.2 6.5e-10 38.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC82640.1 - 5.5e-36 122.0 0.7 4.4e-10 39.0 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med16 PF11635.3 EMC82641.1 - 1.9e-173 578.3 0.2 2.4e-173 578.0 0.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 WD40 PF00400.27 EMC82641.1 - 6e-08 32.2 2.9 2.7e-07 30.1 1.4 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC82641.1 - 0.11 11.2 0.1 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like ARID PF01388.16 EMC82642.1 - 3.1e-28 97.4 0.0 4.9e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain WD40 PF00400.27 EMC82643.1 - 1.4e-25 88.1 6.7 5.3e-11 41.9 0.1 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EMC82643.1 - 0.013 13.6 0.9 0.1 10.7 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SBP_bac_3 PF00497.15 EMC82644.1 - 3.2e-24 85.4 0.0 5.2e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.21 EMC82644.1 - 2e-22 79.4 0.0 4.7e-22 78.2 0.0 1.6 1 1 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 EMC82644.1 - 6.3e-19 67.7 0.7 1.9e-18 66.2 0.3 1.9 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 EMC82644.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Calponin PF00402.13 EMC82645.1 - 3.3e-38 128.6 20.0 2.4e-14 52.3 0.8 4.1 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.26 EMC82645.1 - 2.3e-18 66.2 0.1 4.3e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC82645.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain RNA_pol_Rpb5_C PF01191.14 EMC82646.1 - 2.8e-35 119.7 0.4 4.2e-35 119.1 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EMC82646.1 - 3.2e-10 40.2 0.0 5.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain GSHPx PF00255.14 EMC82647.1 - 2.2e-08 33.4 0.0 2.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EMC82647.1 - 0.048 13.3 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family SH3_1 PF00018.23 EMC82647.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 SH3 domain AAA_34 PF13872.1 EMC82648.1 - 2.8e-135 449.9 0.0 3.9e-135 449.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.1 EMC82648.1 - 2.9e-116 387.7 0.0 4.3e-116 387.1 0.0 1.3 1 0 0 1 1 1 1 Helicase_C-like ResIII PF04851.10 EMC82648.1 - 1.8e-05 24.6 0.0 5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMC82648.1 - 0.0012 18.6 0.1 0.004 16.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC82648.1 - 0.016 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATP-synt_DE_N PF02823.11 EMC82649.1 - 6.3e-20 70.7 0.2 9.5e-20 70.1 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HemX PF04375.9 EMC82649.1 - 0.01 14.4 0.8 0.013 14.0 0.6 1.1 1 0 0 1 1 1 0 HemX DUF4140 PF13600.1 EMC82649.1 - 0.51 10.8 4.1 1 9.8 2.9 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ATP-synt_DE PF00401.15 EMC82649.1 - 2 8.3 10.8 6.9 6.6 7.5 1.9 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RRM_1 PF00076.17 EMC82651.1 - 2.1e-26 91.3 0.1 2.9e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82651.1 - 7e-18 64.3 0.1 9e-18 64.0 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82651.1 - 1.8e-11 43.6 0.1 2.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_IV PF11411.3 EMC82651.1 - 0.022 14.4 3.0 4.8 7.0 0.8 2.5 2 0 0 2 2 2 0 DNA ligase IV RRM_3 PF08777.6 EMC82651.1 - 0.05 13.4 0.2 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif GRP PF07172.6 EMC82651.1 - 0.095 13.1 9.8 0.14 12.6 6.8 1.3 1 0 0 1 1 1 0 Glycine rich protein family PRP38_assoc PF12871.2 EMC82651.1 - 0.41 11.2 13.6 0.044 14.3 6.6 1.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Cornifin PF02389.10 EMC82653.1 - 2.2e-15 56.9 50.3 7.5e-09 35.6 13.1 2.5 1 1 1 2 2 2 2 Cornifin (SPRR) family Pkinase PF00069.20 EMC82654.1 - 3.9e-66 222.8 0.0 4.6e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82654.1 - 3e-25 88.7 0.0 3.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC82654.1 - 0.00098 18.1 0.0 0.0017 17.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMC82654.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMC82654.1 - 0.06 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EMC82654.1 - 0.065 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PWWP PF00855.12 EMC82655.1 - 8.6e-11 41.8 0.4 2.5e-05 24.3 0.1 2.9 2 0 0 2 2 2 2 PWWP domain Oxidored_q6 PF01058.17 EMC82656.1 - 1.6e-06 27.7 0.1 2.5e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF3079 PF11278.3 EMC82656.1 - 0.3 10.6 5.2 6.4 6.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) RRM_1 PF00076.17 EMC82657.1 - 2.6e-38 129.4 0.2 3.6e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82657.1 - 7.8e-35 118.6 0.1 2.8e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82657.1 - 1.2e-18 66.6 0.1 9.3e-09 35.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC82657.1 - 0.00016 21.3 0.2 0.44 10.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CSD PF00313.17 EMC82657.1 - 0.026 14.2 1.3 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF4651 PF15513.1 EMC82657.1 - 0.037 13.4 0.2 9 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Ribosomal_S19 PF00203.16 EMC82658.1 - 3.3e-29 100.3 0.3 4.5e-29 99.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EMC82658.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH TIR_2 PF13676.1 EMC82659.1 - 3.6e-14 52.7 0.0 4.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR PF01582.15 EMC82659.1 - 1.4e-08 34.2 0.0 2.4e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 TIR domain TB2_DP1_HVA22 PF03134.14 EMC82660.1 - 4.3e-37 125.7 3.6 5.2e-37 125.4 2.5 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pkinase PF00069.20 EMC82661.1 - 1.1e-50 172.1 0.0 1.4e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82661.1 - 1.8e-27 96.0 0.0 2.5e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC82661.1 - 0.00014 21.6 0.2 0.46 10.1 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC82661.1 - 0.00053 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC82661.1 - 0.046 12.7 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC82661.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMC82661.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Peptidase_M3 PF01432.15 EMC82662.1 - 1.3e-164 548.5 0.0 1.8e-164 548.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF3740 PF12548.3 EMC82662.1 - 0.053 13.8 0.1 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Sulfatase protein TPR_1 PF00515.23 EMC82663.1 - 8.7e-28 94.7 7.2 3e-10 39.2 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMC82663.1 - 8.8e-26 89.3 6.6 2.7e-18 65.3 0.8 2.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EMC82663.1 - 8.8e-21 72.0 3.5 4.2e-06 26.2 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC82663.1 - 1e-15 56.5 3.0 3.1e-06 26.9 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC82663.1 - 4.7e-14 51.0 3.3 9.3e-06 25.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC82663.1 - 2.6e-13 50.2 2.3 1.3e-07 32.0 0.1 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC82663.1 - 1.9e-12 45.9 0.3 0.0015 18.2 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC82663.1 - 6.2e-11 42.4 0.5 2.7e-07 30.8 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC82663.1 - 6.5e-11 41.8 0.3 0.002 18.5 0.0 4.4 3 1 2 5 5 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC82663.1 - 3.5e-10 39.6 1.2 2.3e-08 33.8 0.2 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC82663.1 - 2.7e-05 23.9 0.1 0.02 14.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EMC82663.1 - 8.8e-05 22.1 0.6 0.26 10.8 0.0 3.1 3 1 0 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.1 EMC82663.1 - 0.00013 21.7 4.6 0.076 12.8 0.0 3.4 3 1 1 4 4 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EMC82663.1 - 0.00035 20.8 0.5 1.3 9.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EMC82663.1 - 0.0012 17.6 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 EMC82663.1 - 0.0017 18.4 1.6 0.021 14.9 0.7 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EMC82663.1 - 0.0025 18.1 0.2 0.54 10.5 0.0 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 EMC82663.1 - 0.032 13.2 0.0 1.6 7.6 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC82663.1 - 0.043 13.7 0.3 13 5.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.7 EMC82663.1 - 0.06 12.9 3.3 0.89 9.1 0.1 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF627) MIT PF04212.13 EMC82663.1 - 0.15 11.9 4.9 6.7 6.6 0.1 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.6 EMC82663.1 - 0.22 10.9 10.5 0.44 10.0 2.4 2.6 2 0 0 2 2 2 0 XPC-binding domain Zip PF02535.17 EMC82664.1 - 2.8e-55 187.5 6.8 3.8e-55 187.1 4.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.6 EMC82664.1 - 8.7 5.5 6.6 0.38 10.0 0.3 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Ras PF00071.17 EMC82665.1 - 5.8e-50 168.8 0.1 6.9e-50 168.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC82665.1 - 5.7e-23 81.6 0.3 9.8e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC82665.1 - 1.3e-07 31.0 0.0 1.8e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC82665.1 - 4.1e-05 23.0 0.1 7.7e-05 22.2 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC82665.1 - 0.00066 18.9 0.3 0.0013 17.9 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EMC82665.1 - 0.0013 17.5 0.3 0.21 10.3 0.1 2.2 2 0 0 2 2 2 2 ArgK protein Gtr1_RagA PF04670.7 EMC82665.1 - 0.0027 16.8 0.1 0.0034 16.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC82665.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC82665.1 - 0.014 15.5 0.1 0.21 11.7 0.0 2.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMC82665.1 - 0.018 14.3 0.3 0.071 12.3 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EMC82665.1 - 0.033 13.3 0.9 0.1 11.7 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EMC82665.1 - 0.039 13.6 0.5 0.12 12.0 0.3 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_32 PF13654.1 EMC82665.1 - 0.049 12.2 1.4 0.94 8.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 EMC82665.1 - 0.064 12.1 0.0 0.85 8.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 EMC82665.1 - 0.069 12.7 0.2 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2408 PF10303.4 EMC82665.1 - 0.09 12.8 1.9 2.2 8.4 1.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) AAA_28 PF13521.1 EMC82665.1 - 0.16 11.9 0.3 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Excalibur PF05901.6 EMC82666.1 - 1.8 8.9 16.7 47 4.4 0.1 6.0 4 2 1 5 5 5 0 Excalibur calcium-binding domain G-gamma PF00631.17 EMC82667.1 - 1.1e-18 66.7 0.0 1.2e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain Ribosomal_L7Ae PF01248.21 EMC82668.1 - 2.6e-16 58.9 0.0 1.1e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Caenor_Her-1 PF09232.5 EMC82668.1 - 0.073 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 SSF PF00474.12 EMC82670.1 - 8.3e-32 110.3 13.3 9.4e-32 110.1 9.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF1014 PF06244.7 EMC82671.1 - 7.4e-09 35.8 5.9 7.4e-09 35.8 4.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) THRAP3_BCLAF1 PF15440.1 EMC82671.1 - 3.2 6.3 20.8 4 5.9 14.4 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Asp-B-Hydro_N PF05279.6 EMC82671.1 - 3.5 7.4 25.6 4.3 7.1 17.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Adeno_VII PF03228.9 EMC82671.1 - 3.6 8.1 14.5 5 7.7 5.2 2.1 2 0 0 2 2 2 0 Adenoviral core protein VII HSP70 PF00012.15 EMC82671.1 - 7.2 4.3 17.8 8.8 4.1 12.3 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF3040 PF11239.3 EMC82671.1 - 7.3 6.7 5.8 23 5.1 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) SK_channel PF03530.9 EMC82672.1 - 2.1e-48 163.0 0.9 3.8e-48 162.2 0.1 1.9 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.11 EMC82672.1 - 6.1e-24 83.6 5.4 1.1e-23 82.8 3.8 1.4 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.11 EMC82672.1 - 1.6e-13 50.1 2.8 1.6e-13 50.1 1.9 2.2 3 0 0 3 3 3 1 Ion channel Occludin_ELL PF07303.8 EMC82673.1 - 1.4e-18 67.4 1.0 4.8e-08 33.6 1.3 2.1 1 1 1 2 2 2 2 Occludin homology domain RVT_1 PF00078.22 EMC82675.1 - 0.097 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.11 EMC82676.1 - 6.8e-16 57.9 0.0 1.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82676.1 - 2.1e-11 43.7 0.1 4.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC82676.1 - 9.8e-09 35.5 1.1 1.6e-07 31.7 0.7 2.4 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC82676.1 - 7.2e-07 29.2 0.1 2.8e-06 27.3 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC82676.1 - 2.7e-06 27.2 0.3 7.9e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain DUF4446 PF14584.1 EMC82676.1 - 0.063 13.0 0.5 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2228 PF10228.4 EMC82677.1 - 2.1e-109 364.9 0.1 2.7e-109 364.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Voltage_CLC PF00654.15 EMC82678.1 - 1.4e-101 340.1 20.1 1.9e-101 339.6 13.9 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EMC82678.1 - 1.2e-12 47.4 0.5 1.6e-06 27.7 0.1 2.4 2 0 0 2 2 2 2 CBS domain SH3_9 PF14604.1 EMC82679.1 - 4.9e-58 192.4 2.3 4e-16 58.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.23 EMC82679.1 - 7.2e-50 166.1 1.8 5e-12 45.0 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.12 EMC82679.1 - 5.1e-36 121.9 1.7 3.3e-09 36.0 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4 PF00097.20 EMC82679.1 - 3.4e-09 36.1 7.0 6.7e-09 35.2 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC82679.1 - 7.2e-09 35.5 8.2 1.6e-08 34.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC82679.1 - 3.2e-08 33.2 8.0 7.2e-08 32.1 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EMC82679.1 - 2.8e-07 30.1 5.7 6.5e-07 28.9 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC82679.1 - 3.8e-07 29.7 6.8 7.1e-07 28.8 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC82679.1 - 3.5e-06 26.5 8.7 6.4e-06 25.7 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC82679.1 - 8.1e-05 22.4 7.8 0.00015 21.5 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC82679.1 - 0.00017 21.0 4.8 0.00017 21.0 3.3 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EMC82679.1 - 0.0023 17.3 5.5 0.005 16.3 3.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMC82679.1 - 0.12 11.9 2.6 0.3 10.6 1.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Trm112p PF03966.11 EMC82679.1 - 1.4 9.2 5.9 4.4 7.7 4.1 1.9 1 0 0 1 1 1 0 Trm112p-like protein adh_short PF00106.20 EMC82680.1 - 4e-34 117.9 2.1 6.7e-34 117.2 0.9 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC82680.1 - 5.6e-29 101.6 0.2 6.8e-29 101.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC82680.1 - 8.3e-17 61.4 2.3 3.8e-16 59.2 0.7 2.0 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EMC82680.1 - 0.00078 18.9 0.2 0.0016 17.9 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC82680.1 - 0.0012 18.8 0.1 0.0022 18.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMC82680.1 - 0.045 13.8 0.2 0.43 10.6 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase I-set PF07679.11 EMC82681.1 - 2.6e-109 357.3 0.0 2.1e-22 78.7 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82681.1 - 1.9e-58 194.4 0.3 3.3e-12 46.3 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 EMC82681.1 - 5.1e-38 129.3 0.2 1.9e-06 28.2 0.0 6.3 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 EMC82681.1 - 1.1e-27 95.9 0.3 0.00015 21.8 0.0 6.3 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 EMC82681.1 - 6.3e-22 77.6 4.1 0.001 18.9 0.0 7.4 6 2 0 6 6 6 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC82681.1 - 1.2e-16 60.4 1.9 0.0079 16.0 0.0 6.2 6 0 0 6 6 6 5 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 EMC82681.1 - 0.00021 21.1 0.0 0.58 10.0 0.0 4.2 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 BiPBP_C PF06832.7 EMC82681.1 - 0.00049 19.9 0.0 5.5 6.9 0.0 4.0 4 0 0 4 4 4 2 Penicillin-Binding Protein C-terminus Family C2-set PF05790.10 EMC82681.1 - 0.017 15.0 0.4 9.1 6.3 0.1 4.3 4 0 0 4 4 4 0 Immunoglobulin C2-set domain DEAD PF00270.24 EMC82682.1 - 1e-19 70.6 0.0 3.5e-19 68.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC82682.1 - 3.6e-09 36.7 6.3 1.3e-07 31.6 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMC82682.1 - 3.6e-05 23.5 0.0 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CAP_N PF01213.14 EMC82683.1 - 0.015 14.6 0.6 0.017 14.4 0.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DXP_synthase_N PF13292.1 EMC82683.1 - 0.018 14.0 0.7 0.022 13.6 0.5 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase zf-B_box PF00643.19 EMC82683.1 - 0.019 14.8 0.7 0.019 14.8 0.5 1.8 2 0 0 2 2 2 0 B-box zinc finger Pox_Ag35 PF03286.9 EMC82683.1 - 0.061 12.8 2.4 0.072 12.6 1.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4570 PF15134.1 EMC82683.1 - 1.3 8.8 6.3 3.5 7.5 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) Annexin PF00191.15 EMC82684.1 - 5.5e-64 211.9 8.5 7.2e-21 73.8 0.1 4.0 4 0 0 4 4 4 4 Annexin BTB PF00651.26 EMC82685.1 - 5.1e-27 94.0 0.4 7.3e-27 93.5 0.3 1.2 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC82685.1 - 4.6e-09 36.1 2.4 4.6e-09 36.1 1.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC82685.1 - 6.9e-07 29.1 12.3 0.0011 19.2 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3342 PF11822.3 EMC82685.1 - 2e-06 27.1 0.1 2e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.21 EMC82685.1 - 4.1e-05 23.6 17.2 0.00026 21.1 0.7 3.3 4 0 0 4 4 3 2 Zinc finger, C2H2 type BTB_2 PF02214.17 EMC82685.1 - 0.00055 20.0 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.2 EMC82685.1 - 0.015 15.4 2.7 0.082 13.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF1722 PF08349.6 EMC82685.1 - 0.034 14.0 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Zn-ribbon_8 PF09723.5 EMC82685.1 - 0.048 13.6 0.6 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMC82685.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EMC82685.1 - 0.32 11.1 3.8 0.7 10.0 2.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EMC82685.1 - 0.48 10.6 0.1 0.48 10.6 0.0 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC82685.1 - 0.84 9.9 7.5 0.16 12.2 1.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EMC82686.1 - 0.0026 17.9 0.6 0.0026 17.9 0.4 1.8 2 0 0 2 2 2 1 Zinc-finger double domain Pkinase PF00069.20 EMC82687.1 - 7.7e-67 225.1 0.0 8.7e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82687.1 - 4.3e-35 121.0 0.0 5e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC82687.1 - 1e-05 24.6 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC82687.1 - 0.00042 19.4 0.0 0.0006 18.9 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC82687.1 - 0.0047 16.3 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Arm PF00514.18 EMC82688.1 - 3.6e-89 289.9 18.8 3.9e-14 51.8 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC82688.1 - 4.4e-27 94.1 0.0 6.8e-09 35.9 0.0 5.6 2 1 2 5 5 5 4 HEAT repeats IBB PF01749.15 EMC82688.1 - 7.9e-26 90.0 2.6 1.4e-25 89.2 1.8 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EMC82688.1 - 4.4e-22 77.9 5.5 1.1e-06 28.8 0.0 5.8 4 2 2 6 6 6 5 HEAT-like repeat HEAT PF02985.17 EMC82688.1 - 1.3e-12 46.6 14.9 0.0005 19.9 0.0 8.0 10 0 0 10 10 10 2 HEAT repeat Arm_2 PF04826.8 EMC82688.1 - 6.1e-08 32.0 0.0 0.014 14.4 0.0 2.8 1 1 2 3 3 3 2 Armadillo-like RICTOR_V PF14668.1 EMC82688.1 - 3.8e-06 26.7 4.2 0.95 9.4 0.0 5.2 5 1 1 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 EMC82688.1 - 1.5e-05 24.8 0.0 0.27 11.1 0.0 4.4 2 1 3 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 EMC82688.1 - 0.00042 20.5 0.2 7.2 7.3 0.0 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EMC82688.1 - 0.0083 14.4 0.1 0.11 10.7 0.1 2.4 1 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Taxilin PF09728.4 EMC82689.1 - 2.5e-106 355.2 70.6 2.9e-106 355.0 49.0 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF869 PF05911.6 EMC82689.1 - 0.0011 17.3 10.6 0.0011 17.3 7.3 2.3 1 1 1 2 2 2 1 Plant protein of unknown function (DUF869) FlaC_arch PF05377.6 EMC82689.1 - 0.77 9.6 16.8 0.92 9.4 0.6 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Tropomyosin PF00261.15 EMC82689.1 - 1.9 7.4 59.4 0.028 13.5 19.7 2.2 1 1 1 2 2 2 0 Tropomyosin Shugoshin_N PF07558.6 EMC82689.1 - 3.8 7.2 18.1 1.2 8.8 0.6 4.5 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region SpoVAD PF07451.6 EMC82689.1 - 3.9 5.8 7.7 6.7 5.0 0.6 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) WD40 PF00400.27 EMC82690.1 - 2.3e-28 96.9 3.4 2.1e-09 36.8 1.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 EMC82690.1 - 0.054 11.6 0.0 0.29 9.2 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ins_P5_2-kin PF06090.7 EMC82690.1 - 0.11 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Pkinase_Tyr PF07714.12 EMC82691.1 - 3.5e-62 209.8 0.0 4e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC82691.1 - 1.6e-26 93.0 0.0 1.8e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EMC82691.1 - 0.075 12.7 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 EMC82692.1 - 6.2e-82 275.3 0.1 1.1e-81 274.5 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain SDA1 PF05285.7 EMC82692.1 - 0.1 11.8 19.6 0.13 11.5 13.6 1.1 1 0 0 1 1 1 0 SDA1 MARCKS PF02063.12 EMC82693.1 - 1.9e-14 54.2 32.1 2.1e-14 54.0 22.3 1.0 1 0 0 1 1 1 1 MARCKS family Tmp39 PF10271.4 EMC82694.1 - 1e-195 650.3 19.3 1.3e-195 650.0 13.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein KH_1 PF00013.24 EMC82696.1 - 2.2e-09 36.7 0.3 5.1e-09 35.6 0.2 1.6 1 1 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC82696.1 - 9.6e-09 34.7 0.1 1.8e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_5 PF13184.1 EMC82696.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 NusA-like KH domain KH_2 PF07650.12 EMC82696.1 - 0.034 13.6 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 KH domain Y_phosphatase PF00102.22 EMC82697.1 - 6.4e-12 45.3 0.0 9.2e-09 34.9 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EMC82697.1 - 4.3e-09 36.0 0.0 6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC82697.1 - 0.056 13.6 0.2 0.14 12.4 0.1 1.6 1 1 1 2 2 2 0 Tyrosine phosphatase family HrpB1_HrpK PF09613.5 EMC82698.1 - 0.11 11.9 20.8 0.33 10.4 0.7 3.6 2 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Collagen PF01391.13 EMC82699.1 - 2.8e-22 78.0 107.9 1.6e-09 37.1 21.6 4.2 3 1 1 4 4 4 4 Collagen triple helix repeat (20 copies) EF-hand_1 PF00036.27 EMC82700.1 - 2e-20 70.4 0.1 1.2e-06 27.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EMC82700.1 - 6.2e-18 64.7 0.0 5.1e-08 32.9 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC82700.1 - 5.4e-17 60.0 0.0 7.4e-06 25.4 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EMC82700.1 - 2.2e-15 55.1 0.1 2.2e-05 23.5 0.0 3.5 3 0 0 3 3 3 3 EF hand Collagen PF01391.13 EMC82700.1 - 2.4e-12 46.2 62.0 9.5e-09 34.6 18.1 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) EF-hand_8 PF13833.1 EMC82700.1 - 1e-10 41.0 0.1 0.00012 21.5 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_2 PF09068.6 EMC82700.1 - 0.0015 18.5 0.0 12 6.0 0.0 3.2 1 1 2 3 3 3 1 EF hand EF-hand_9 PF14658.1 EMC82700.1 - 0.046 13.6 0.0 16 5.4 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain OST-HTH PF12872.2 EMC82700.1 - 0.065 13.0 0.1 0.37 10.6 0.0 2.3 1 1 1 2 2 2 0 OST-HTH/LOTUS domain Toprim_2 PF13155.1 EMC82700.1 - 0.14 12.5 0.0 9.8 6.5 0.0 2.2 1 1 1 2 2 2 0 Toprim-like KCNQ_channel PF03520.9 EMC82701.1 - 9e-85 283.0 0.1 1.1e-84 282.7 0.1 1.1 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel CBFD_NFYB_HMF PF00808.18 EMC82702.1 - 7.4e-22 77.1 2.7 3.2e-21 75.1 0.9 2.4 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC82702.1 - 4.4e-12 45.9 0.4 1.4e-11 44.3 0.2 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 C2 PF00168.25 EMC82703.1 - 3.9e-13 49.0 0.0 7.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain WG_beta_rep PF14903.1 EMC82703.1 - 0.1 12.8 0.0 0.45 10.8 0.0 2.1 1 1 0 1 1 1 0 WG containing repeat ArfGap PF01412.13 EMC82704.1 - 6e-33 113.1 0.5 1e-32 112.3 0.1 1.5 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf Collagen PF01391.13 EMC82705.1 - 3e-67 222.0 274.3 1.4e-09 37.3 19.2 10.2 3 3 7 10 10 10 10 Collagen triple helix repeat (20 copies) Connexin PF00029.14 EMC82708.1 - 2.5e-48 162.5 0.3 2.5e-48 162.5 0.2 1.8 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 EMC82708.1 - 1.6e-26 91.8 7.1 3.9e-26 90.6 4.9 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain CcmB PF03379.8 EMC82708.1 - 0.066 12.4 0.5 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 CcmB protein Connexin PF00029.14 EMC82709.1 - 3.6e-51 171.7 0.5 3.6e-51 171.7 0.3 1.7 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 EMC82709.1 - 3.6e-26 90.7 3.6 9e-26 89.4 2.5 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF443 PF04276.7 EMC82709.1 - 0.02 14.3 1.2 0.73 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF443) UCR_TM PF02921.9 EMC82709.1 - 0.04 14.1 0.4 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region 7tm_1 PF00001.16 EMC82709.1 - 0.055 12.5 5.6 0.22 10.6 0.9 2.3 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) PRA1 PF03208.14 EMC82709.1 - 0.5 9.6 4.1 0.96 8.7 0.0 2.8 2 2 0 2 2 2 0 PRA1 family protein NB PF04159.8 EMC82709.1 - 3.3 7.5 0.0 3.3 7.5 0.0 3.2 3 1 1 4 4 4 0 NB glycoprotein Connexin PF00029.14 EMC82710.1 - 3.3e-53 178.2 0.2 6.4e-53 177.3 0.1 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC82710.1 - 1.1e-32 111.6 0.8 2.9e-32 110.2 0.5 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin43 PF03508.8 EMC82710.1 - 0.00023 20.3 2.9 0.0004 19.5 2.0 1.4 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) Herpes_LMP2 PF07415.6 EMC82710.1 - 0.2 10.2 0.1 0.2 10.2 0.1 2.1 2 1 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein DoxX_2 PF13564.1 EMC82712.1 - 5.1e-08 32.8 3.8 5.8e-08 32.6 2.7 1.1 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.7 EMC82712.1 - 0.00052 20.3 1.6 0.00052 20.3 1.1 1.9 1 1 1 2 2 2 1 DoxX RRM_1 PF00076.17 EMC82713.1 - 1.7e-30 104.4 0.1 6e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82713.1 - 1e-22 79.8 0.4 2e-10 40.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 EMC82713.1 - 3.6e-21 75.3 0.2 1.4e-20 73.4 0.2 2.1 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_5 PF13893.1 EMC82713.1 - 3.1e-14 52.5 0.0 2.6e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3256 PF11644.3 EMC82713.1 - 0.15 11.5 1.3 0.24 10.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) DUF3089 PF11288.3 EMC82715.1 - 0.067 12.3 0.2 0.086 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Y_Y_Y PF07495.8 EMC82717.1 - 1.3e-13 50.4 1.6 0.0038 16.9 0.0 5.2 5 0 0 5 5 5 3 Y_Y_Y domain DUF4625 PF15418.1 EMC82717.1 - 1.1e-12 48.2 0.1 0.013 15.6 0.0 4.5 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) Big_3_4 PF13754.1 EMC82717.1 - 3.6e-10 40.0 20.3 0.00035 20.8 0.0 5.5 5 0 0 5 5 4 3 Bacterial Ig-like domain (group 3) PKD PF00801.15 EMC82717.1 - 1.1e-07 31.5 21.5 0.0048 16.6 0.1 6.2 5 2 0 5 5 5 3 PKD domain He_PIG PF05345.7 EMC82717.1 - 1.6e-05 24.7 11.4 0.15 12.1 0.0 5.6 6 0 0 6 6 5 2 Putative Ig domain DUF4399 PF14347.1 EMC82717.1 - 0.00024 21.0 0.3 8.8 6.4 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4399) Cadherin PF00028.12 EMC82717.1 - 0.00053 20.1 6.8 2.7 8.3 0.1 4.9 5 0 0 5 5 5 1 Cadherin domain fn3 PF00041.16 EMC82717.1 - 0.00059 19.9 1.3 0.14 12.3 0.0 4.0 3 1 0 3 3 3 1 Fibronectin type III domain EGF_2 PF07974.8 EMC82717.1 - 0.0013 18.8 4.4 0.0027 17.8 3.1 1.4 1 0 0 1 1 1 1 EGF-like domain Cna_B PF05738.8 EMC82717.1 - 0.019 14.6 1.8 1.6 8.5 0.1 3.7 3 0 0 3 3 3 0 Cna protein B-type domain DUF3481 PF11980.3 EMC82717.1 - 0.064 13.0 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Big_3_2 PF12245.3 EMC82717.1 - 0.072 12.6 0.2 6.7 6.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NOD PF06816.8 EMC82717.1 - 0.42 9.7 2.9 3.2 6.9 0.2 2.9 2 1 1 3 3 3 0 NOTCH protein TF_AP-2 PF03299.9 EMC82718.1 - 1.8e-95 318.4 0.0 2.3e-95 318.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 Proteasome PF00227.21 EMC82719.1 - 1.9e-35 121.9 0.0 2.2e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4653 PF15546.1 EMC82720.1 - 5.7e-42 143.6 6.7 8.3e-41 139.8 3.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4653) Piwi PF02171.12 EMC82722.1 - 3.2e-102 341.5 0.0 5e-102 340.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EMC82722.1 - 8.7e-40 135.1 2.8 1.7e-39 134.1 2.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EMC82722.1 - 1.7e-21 75.3 0.0 3.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ATP_bind_4 PF01902.12 EMC82722.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-binding region Piwi PF02171.12 EMC82723.1 - 1.6e-102 342.5 0.0 2.3e-102 342.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EMC82723.1 - 2.6e-41 140.0 2.1 4.5e-41 139.3 1.4 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EMC82723.1 - 4.1e-22 77.2 0.0 7.9e-22 76.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Tautomerase_3 PF14832.1 EMC82723.1 - 0.02 14.9 0.1 8.6 6.3 0.0 3.0 3 0 0 3 3 3 0 Putative oxalocrotonate tautomerase enzyme DUF3465 PF11948.3 EMC82723.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) DUF2344 PF10105.4 EMC82723.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Piwi PF02171.12 EMC82724.1 - 5e-110 367.2 0.0 7e-110 366.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EMC82724.1 - 2.2e-39 133.8 1.3 3.6e-39 133.1 0.9 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EMC82724.1 - 1e-21 76.0 0.0 1.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF3465 PF11948.3 EMC82724.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) DUF2678 PF10856.3 EMC82724.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF2344 PF10105.4 EMC82724.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Tektin PF03148.9 EMC82725.1 - 7.7e-118 393.3 38.1 8.7e-118 393.2 26.4 1.0 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.7 EMC82725.1 - 0.18 11.6 16.0 0.15 11.8 0.9 4.0 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EMC82725.1 - 0.41 10.5 9.9 0.77 9.6 0.2 3.9 3 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Ded_cyto PF06920.8 EMC82725.1 - 1.4 8.1 6.2 1.2 8.4 0.2 2.8 2 1 0 2 2 2 0 Dedicator of cytokinesis DUF3373 PF11853.3 EMC82725.1 - 8.3 4.8 7.1 1.2e+02 0.9 4.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) ADP_ribosyl_GH PF03747.9 EMC82726.1 - 8.8e-43 147.1 0.0 1e-42 146.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase TPR_11 PF13414.1 EMC82726.1 - 0.0037 16.8 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 EMC82726.1 - 0.12 12.6 0.9 0.94 9.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Collagen PF01391.13 EMC82727.1 - 2.3e-55 183.9 252.7 7.6e-08 31.7 14.8 9.4 1 1 5 6 6 6 4 Collagen triple helix repeat (20 copies) C1q PF00386.16 EMC82727.1 - 1.1e-38 132.1 0.1 1.3e-38 131.8 0.1 1.1 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 EMC82727.1 - 0.11 12.0 1.3 2.3 7.8 0.9 2.0 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family TRAPP PF04051.11 EMC82728.1 - 4.8e-40 136.5 0.0 5.4e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component THRAP3_BCLAF1 PF15440.1 EMC82729.1 - 1.7e-195 651.5 120.1 1.7e-195 651.5 83.3 2.6 3 0 0 3 3 3 1 THRAP3/BCLAF1 family FAM176 PF14851.1 EMC82730.1 - 9.8e-53 177.9 0.1 1.4e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 FAM176 family Nucleoplasmin PF03066.10 EMC82730.1 - 0.0087 15.5 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 EMC82730.1 - 0.8 9.9 8.3 1.3 9.2 5.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 EMC82731.1 - 2.3e-39 135.1 0.0 3.3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82731.1 - 9.8e-21 73.9 0.1 1.6e-20 73.2 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC82731.1 - 1.5e-05 24.1 0.1 3.6e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC82731.1 - 0.062 12.3 0.1 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM PF01423.17 EMC82732.1 - 1.9e-10 40.1 0.2 2.8e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain Oscp1 PF10188.4 EMC82733.1 - 4.1e-64 215.5 2.6 6.6e-64 214.8 1.8 1.3 1 0 0 1 1 1 1 Organic solute transport protein 1 Ribosomal_S15 PF00312.17 EMC82734.1 - 3.1e-21 74.9 2.1 4.4e-21 74.4 1.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S15 DUF2383 PF09537.5 EMC82734.1 - 0.054 13.7 1.0 0.072 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) ADIP PF11559.3 EMC82734.1 - 1.1 9.1 8.5 0.057 13.3 1.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FliJ PF02050.11 EMC82734.1 - 2.4 8.2 14.6 3 7.9 1.1 2.3 2 1 0 2 2 2 0 Flagellar FliJ protein ATP_bind_3 PF01171.15 EMC82734.1 - 7.5 6.0 8.0 0.34 10.3 0.6 2.1 2 1 0 2 2 2 0 PP-loop family Lep_receptor_Ig PF06328.6 EMC82735.1 - 7e-09 35.4 0.1 3.2e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Ig-like C2-type domain EpoR_lig-bind PF09067.5 EMC82735.1 - 7.2e-06 25.9 0.0 2.7e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding C2-set_2 PF08205.7 EMC82735.1 - 0.059 13.2 2.3 1 9.3 0.1 2.6 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain IL6Ra-bind PF09240.5 EMC82735.1 - 0.3 11.2 3.0 0.21 11.7 0.7 1.9 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding ANF_receptor PF01094.23 EMC82736.1 - 3.3e-63 213.5 0.0 4.5e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 EMC82736.1 - 2.1e-37 128.1 0.5 8.7e-37 126.1 0.0 2.0 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 EMC82736.1 - 3.5e-28 97.3 2.7 2.1e-27 94.8 0.1 3.3 4 0 0 4 4 4 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC82736.1 - 9.2e-22 77.3 0.0 1.6e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 EMC82736.1 - 4.9e-05 22.8 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein DUF2569 PF10754.4 EMC82736.1 - 0.0043 17.2 0.1 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) Fibrinogen_BP PF08017.6 EMC82737.1 - 0.0074 14.5 0.0 0.0094 14.2 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein DUF834 PF05754.9 EMC82737.1 - 0.01 15.6 41.3 2.5 7.9 1.1 6.4 1 1 8 9 9 9 0 Domain of unknown function (DUF834) RNase_Zc3h12a PF11977.3 EMC82738.1 - 2.6e-64 215.7 0.0 2.4e-63 212.6 0.0 2.0 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH PF00642.19 EMC82738.1 - 0.026 14.1 2.7 0.026 14.1 1.9 2.5 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMC82738.1 - 0.24 11.4 7.0 0.47 10.5 4.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type SURF2 PF05477.6 EMC82739.1 - 0.02 14.0 3.0 0.024 13.7 2.1 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Myc_N PF01056.13 EMC82739.1 - 0.16 11.0 3.5 0.19 10.8 2.5 1.0 1 0 0 1 1 1 0 Myc amino-terminal region FHA PF00498.21 EMC82740.1 - 2.8e-17 62.5 0.0 5.1e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 EMC82740.1 - 7.1 4.9 19.0 8.5 4.7 13.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ax_dynein_light PF10211.4 EMC82741.1 - 5.2e-65 218.8 19.0 6.2e-65 218.5 13.2 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain DivIC PF04977.10 EMC82741.1 - 0.012 15.0 2.9 0.012 15.0 2.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Syntaxin-6_N PF09177.6 EMC82741.1 - 0.045 14.1 6.7 0.078 13.3 4.6 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal IL31 PF15209.1 EMC82741.1 - 0.087 12.4 2.1 0.14 11.7 0.5 2.1 2 1 0 2 2 2 0 Interleukin 31 Spc24 PF08286.6 EMC82741.1 - 0.21 11.2 9.4 0.33 10.6 6.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3373 PF11853.3 EMC82741.1 - 0.35 9.3 4.7 0.42 9.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) APG6 PF04111.7 EMC82741.1 - 0.43 9.5 9.9 0.45 9.5 6.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GrpE PF01025.14 EMC82741.1 - 0.47 9.9 12.4 0.64 9.5 8.2 1.5 1 1 0 1 1 1 0 GrpE MobC PF05713.6 EMC82741.1 - 0.71 9.8 5.1 0.67 9.9 0.5 2.5 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) V_ATPase_I PF01496.14 EMC82741.1 - 1.8 6.3 6.8 1.9 6.2 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 EMC82741.1 - 2 8.6 13.5 0.57 10.3 6.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF244 PF03112.9 EMC82741.1 - 3.4 7.1 8.6 5.5 6.5 5.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF NGP1NT PF08153.7 EMC82742.1 - 3e-48 163.0 0.9 9.1e-48 161.4 0.6 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EMC82742.1 - 1.3e-17 63.8 0.3 1.3e-13 50.9 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC82742.1 - 1.7e-05 24.1 0.0 9e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMC82742.1 - 0.00074 18.7 0.1 0.0027 16.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMC82742.1 - 0.0038 16.6 0.0 0.74 9.2 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMC82742.1 - 0.0086 15.3 0.1 0.25 10.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EMC82742.1 - 0.055 13.2 8.8 0.078 12.7 0.6 4.5 3 1 0 3 3 3 0 Dynamin family TSP_1 PF00090.14 EMC82743.1 - 0.00045 20.2 4.2 0.00045 20.2 2.9 3.9 3 1 1 4 4 4 1 Thrombospondin type 1 domain Fer4_3 PF12798.2 EMC82743.1 - 0.14 12.7 12.0 1.9 9.2 0.3 5.2 5 2 0 5 5 5 0 4Fe-4S binding domain CK2S PF15011.1 EMC82744.1 - 2.3e-08 34.0 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Casein Kinase 2 substrate Inhibitor_G39P PF11417.3 EMC82744.1 - 0.048 13.6 0.0 0.061 13.3 0.0 1.1 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P Borealin PF10512.4 EMC82745.1 - 1.2e-28 99.3 0.4 1.7e-28 98.8 0.0 1.3 2 0 0 2 2 2 1 Cell division cycle-associated protein 8 Axin_b-cat_bind PF08833.5 EMC82745.1 - 0.037 13.7 4.3 0.064 12.9 0.0 2.6 2 1 0 2 2 2 0 Axin beta-catenin binding domain Sua5_yciO_yrdC PF01300.13 EMC82746.1 - 1.3e-24 86.4 0.0 1.5e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination zf-H2C2_2 PF13465.1 EMC82747.1 - 3.6e-30 102.7 46.5 1.5e-08 34.5 0.3 7.3 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC82747.1 - 2.7e-27 93.4 39.9 0.00015 21.9 1.0 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC82747.1 - 9.3e-19 66.3 35.0 0.0026 17.9 0.5 6.8 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC82747.1 - 5.5e-06 26.3 23.2 0.012 15.7 1.5 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding Marek_A PF02124.10 EMC82747.1 - 0.0014 18.1 1.9 0.77 9.1 0.1 3.1 2 1 1 3 3 3 2 Marek's disease glycoprotein A zf-met PF12874.2 EMC82747.1 - 0.077 13.2 0.5 0.077 13.2 0.4 5.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Exo_endo_phos PF03372.18 EMC82748.1 - 2.2e-32 112.9 0.0 3.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EMC82748.1 - 1e-16 60.8 0.0 2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EMC82750.1 - 4e-48 161.3 71.8 3.1e-12 46.3 4.2 5.1 5 0 0 5 5 5 5 LIM domain Ureidogly_hydro PF04115.7 EMC82750.1 - 0.034 13.5 0.0 0.62 9.3 0.0 2.6 1 1 2 3 3 3 0 Ureidoglycolate hydrolase Utp11 PF03998.8 EMC82752.1 - 2.6e-68 230.4 22.4 2.9e-68 230.3 15.5 1.0 1 0 0 1 1 1 1 Utp11 protein GvpK PF05121.7 EMC82752.1 - 0.31 10.8 2.8 4 7.3 1.0 2.4 1 1 1 2 2 2 0 Gas vesicle protein K Takusan PF04822.8 EMC82752.1 - 1.7 8.4 7.2 2.9 7.7 0.2 3.0 3 1 0 3 3 3 0 Takusan Pou PF00157.12 EMC82753.1 - 4.5e-39 131.9 0.3 9.5e-39 130.9 0.2 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 EMC82753.1 - 4.9e-19 67.6 0.1 1.2e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 EMC82753.1 - 2.9e-05 24.1 0.0 0.009 16.1 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain Homeobox_KN PF05920.6 EMC82753.1 - 0.023 14.3 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain HTH_19 PF12844.2 EMC82753.1 - 0.028 14.4 0.0 0.68 10.0 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain Cut8_N PF14482.1 EMC82753.1 - 0.1 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Gtr1_RagA PF04670.7 EMC82754.1 - 3.4e-63 212.8 2.5 4.6e-63 212.4 1.8 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EMC82754.1 - 0.019 14.2 0.1 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family TSC22 PF01166.13 EMC82755.1 - 0.016 15.1 1.1 0.017 15.0 0.8 1.1 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 EMC82755.1 - 0.028 14.6 2.8 0.029 14.6 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EMC82755.1 - 0.038 14.3 0.5 0.038 14.3 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EMC82755.1 - 0.039 13.3 0.5 0.044 13.2 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) HALZ PF02183.13 EMC82755.1 - 0.084 12.6 3.1 0.17 11.5 2.1 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4298 PF14131.1 EMC82755.1 - 0.088 12.6 0.5 0.093 12.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Herpes_BLRF2 PF05812.7 EMC82755.1 - 0.11 12.2 1.9 0.12 12.2 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Tropomyosin_1 PF12718.2 EMC82755.1 - 0.12 12.2 3.0 0.12 12.1 2.1 1.0 1 0 0 1 1 1 0 Tropomyosin like DivIC PF04977.10 EMC82755.1 - 0.15 11.5 1.5 0.15 11.5 1.0 1.0 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 EMC82755.1 - 0.2 11.4 2.4 0.23 11.3 1.7 1.1 1 0 0 1 1 1 0 Basic region leucine zipper Connexin PF00029.14 EMC82756.1 - 6e-50 167.7 0.2 1.1e-49 166.9 0.1 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC82756.1 - 8.2e-34 115.2 0.4 1.8e-33 114.1 0.3 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF4618 PF15397.1 EMC82756.1 - 0.0064 15.8 0.3 0.0089 15.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) CemA PF03040.9 EMC82756.1 - 7.3 6.1 6.6 12 5.4 0.0 2.8 2 1 1 3 3 3 0 CemA family FHA PF00498.21 EMC82757.1 - 1.8e-15 56.8 0.1 3.9e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain Syntaxin_2 PF14523.1 EMC82759.1 - 2.3e-22 78.9 15.3 3.2e-22 78.4 6.7 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EMC82759.1 - 3.9e-21 74.5 4.5 3.9e-21 74.5 3.1 2.6 3 0 0 3 3 3 1 SNARE domain Herpes_US9 PF06072.6 EMC82759.1 - 0.00038 20.2 0.1 0.00086 19.0 0.0 1.6 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 Syntaxin PF00804.20 EMC82759.1 - 0.0025 17.9 5.4 0.0025 17.9 3.8 3.0 2 1 1 3 3 3 1 Syntaxin TBPIP PF07106.8 EMC82759.1 - 0.0043 16.6 4.8 0.0043 16.6 3.3 2.1 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 EMC82759.1 - 0.022 14.5 3.8 0.022 14.5 2.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Synaptobrevin PF00957.16 EMC82759.1 - 0.4 10.2 11.2 0.28 10.8 1.7 2.9 2 1 0 2 2 2 0 Synaptobrevin DUF3782 PF12644.2 EMC82759.1 - 0.52 10.1 2.8 13 5.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Mit_KHE1 PF10173.4 EMC82759.1 - 0.98 9.2 4.6 2 8.2 3.2 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related GAS PF13851.1 EMC82759.1 - 3.9 6.6 20.0 3.9 6.6 1.7 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prominin PF05478.6 EMC82759.1 - 5.4 4.4 9.1 5.2 4.4 0.5 2.1 1 1 0 2 2 2 0 Prominin CDC37_N PF03234.9 EMC82759.1 - 5.4 7.3 17.9 0.37 11.0 0.4 2.6 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding CITED PF04487.7 EMC82760.1 - 4.7e-85 285.1 15.0 5.2e-85 285.0 10.4 1.0 1 0 0 1 1 1 1 CITED DUF39 PF01837.11 EMC82760.1 - 0.044 12.4 0.0 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF39 MBT PF02820.13 EMC82762.1 - 9.9e-60 198.3 0.0 8.2e-30 102.5 0.0 2.4 2 0 0 2 2 2 2 mbt repeat DUF3588 PF12140.3 EMC82762.1 - 1.6e-47 160.4 0.3 2.5e-47 159.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 EMC82762.1 - 1.5e-15 57.0 0.1 3.1e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC82762.1 - 3.3e-07 30.0 0.0 7.5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC82762.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Endothelin PF00322.12 EMC82763.1 - 6.5e-20 70.0 13.3 6.2e-19 66.9 3.0 2.3 2 0 0 2 2 2 2 Endothelin family Serinc PF03348.10 EMC82765.1 - 2.4e-92 309.8 17.5 2.7e-92 309.7 12.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Lipocalin PF00061.18 EMC82766.1 - 8.2e-23 80.9 0.7 9.5e-23 80.7 0.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 EMC82766.1 - 6.4e-05 22.6 0.9 8.6e-05 22.2 0.6 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.14 EMC82766.1 - 0.51 10.0 4.6 0.44 10.2 0.9 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain S1 PF00575.18 EMC82767.1 - 1.1e-11 44.6 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain zf-CCHC_3 PF13917.1 EMC82767.1 - 0.00021 20.9 1.5 0.00035 20.2 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EMC82767.1 - 0.028 13.8 0.6 0.061 12.8 0.4 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CHORD PF04968.7 EMC82767.1 - 0.047 13.9 2.0 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 CHORD zf-CCHC PF00098.18 EMC82767.1 - 0.068 13.1 6.7 0.15 12.0 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EMC82767.1 - 0.88 9.2 4.0 1.9 8.2 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Toxin_14 PF07829.6 EMC82767.1 - 5.9 6.7 7.2 17 5.2 0.5 2.6 3 0 0 3 3 3 0 Alpha-A conotoxin PIVA-like protein WD40 PF00400.27 EMC82768.1 - 3.4e-65 213.7 5.0 6.2e-11 41.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC82768.1 - 5.2e-09 36.0 0.3 0.0063 16.2 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMC82768.1 - 0.0003 19.1 0.1 0.46 8.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EMC82768.1 - 0.0045 15.1 6.0 1.1 7.2 0.0 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 EMC82768.1 - 0.068 12.8 0.0 0.53 9.9 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NKAIN PF05640.9 EMC82769.1 - 8.2e-33 113.0 2.1 8.9e-33 112.9 1.5 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein UNC-50 PF05216.8 EMC82769.1 - 0.046 12.9 0.2 0.051 12.7 0.2 1.0 1 0 0 1 1 1 0 UNC-50 family DUF4190 PF13828.1 EMC82769.1 - 0.21 11.1 2.1 0.46 10.0 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) NKAIN PF05640.9 EMC82770.1 - 3.3e-44 150.2 0.0 3.7e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein PUF PF00806.14 EMC82771.1 - 7.2e-74 239.3 8.3 4.3e-09 35.3 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 EMC82771.1 - 0.58 9.9 5.5 2.9 7.6 0.0 3.6 3 1 0 4 4 4 0 CPL (NUC119) domain Mt_ATP-synt_B PF05405.9 EMC82771.1 - 1.2 8.5 3.2 10 5.5 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mtp PF03821.11 EMC82774.1 - 1.7e-73 246.8 12.3 2.2e-73 246.5 8.5 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter VWA PF00092.23 EMC82775.1 - 9.4e-99 328.4 4.5 5.9e-51 172.7 0.3 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 EMC82775.1 - 3.1e-33 115.3 0.1 8.6e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 EMC82775.1 - 3.5e-15 56.0 0.0 2e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.4 EMC82775.1 - 1.3e-11 43.6 3.3 4.8e-11 41.8 2.3 2.1 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin FXa_inhibition PF14670.1 EMC82775.1 - 3.3e-10 39.8 8.7 6.5e-10 38.9 6.0 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC82775.1 - 3.1e-06 26.6 1.0 8.1e-06 25.3 0.7 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_CA PF07645.10 EMC82775.1 - 4.2e-06 26.6 7.3 8.8e-06 25.6 5.0 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.22 EMC82775.1 - 0.00086 19.2 4.9 0.00086 19.2 3.4 1.9 2 0 0 2 2 1 1 EGF-like domain Med25_VWA PF11265.3 EMC82775.1 - 0.018 14.0 0.0 3.8 6.4 0.0 2.6 2 1 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A DUF2242 PF10001.4 EMC82775.1 - 0.044 13.6 0.4 4.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2242) EGF_3 PF12947.2 EMC82775.1 - 2.2 8.3 15.3 0.19 11.6 7.2 1.8 2 0 0 2 2 2 0 EGF domain Methyltransf_23 PF13489.1 EMC82776.1 - 1.6 8.4 7.7 72 3.0 0.0 4.7 6 1 0 6 6 6 0 Methyltransferase domain ADH_zinc_N PF00107.21 EMC82778.1 - 5.5e-19 68.0 0.0 8.2e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC82778.1 - 4e-11 42.6 0.0 1.1e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMC82778.1 - 1.2e-06 29.3 0.0 2.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding_2 PF13380.1 EMC82778.1 - 0.023 14.8 0.1 0.057 13.5 0.0 1.8 1 1 0 1 1 1 0 CoA binding domain RRM_1 PF00076.17 EMC82779.1 - 7e-21 73.6 0.0 2.4e-14 52.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82779.1 - 2.6e-11 43.3 0.0 1.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82779.1 - 6.1e-10 38.7 0.0 0.00039 20.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC82779.1 - 7.8e-06 25.6 0.7 2.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif MBT PF02820.13 EMC82780.1 - 9.5e-95 310.6 0.5 5.6e-32 109.4 0.0 3.2 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.13 EMC82780.1 - 3.5e-13 49.0 10.0 9.1e-13 47.6 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C2HC type Glyco_hydro_2_N PF02837.13 EMC82780.1 - 0.00091 18.8 0.1 1.6 8.2 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 2, sugar binding domain Tudor-knot PF11717.3 EMC82780.1 - 0.5 10.0 7.1 0.87 9.3 0.6 3.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DuffyBP_N PF12377.3 EMC82781.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Duffy binding protein N terminal CENP-T PF15511.1 EMC82782.1 - 0.00025 20.4 35.8 0.00029 20.2 24.8 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T SDA1 PF05285.7 EMC82782.1 - 0.00053 19.3 51.6 0.00066 19.0 35.7 1.1 1 0 0 1 1 1 1 SDA1 DUF1510 PF07423.6 EMC82782.1 - 0.03 13.7 49.8 0.042 13.2 34.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 EMC82782.1 - 0.046 13.0 17.3 0.055 12.7 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BUD22 PF09073.5 EMC82782.1 - 0.096 11.7 49.9 0.12 11.4 34.6 1.1 1 0 0 1 1 1 0 BUD22 Nha1_C PF08619.5 EMC82782.1 - 0.18 11.0 36.4 0.27 10.4 25.3 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Hid1 PF12722.2 EMC82782.1 - 0.61 7.6 22.0 0.7 7.4 15.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 EMC82782.1 - 1.4 7.9 22.2 1.7 7.7 15.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2201_N PF13203.1 EMC82782.1 - 1.7 7.7 18.4 2.3 7.2 12.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.7 EMC82782.1 - 2.4 5.9 72.2 5.6 4.7 50.1 1.4 1 1 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 EMC82782.1 - 2.7 5.5 28.6 4.1 4.9 19.8 1.3 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 EMC82782.1 - 8.4 6.1 8.0 12 5.7 5.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2371 PF10177.4 EMC82783.1 - 1.7e-34 118.6 0.0 2.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) PIRT PF15099.1 EMC82783.1 - 0.15 11.3 0.4 3 7.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2065 PF09838.4 EMC82783.1 - 1.4 8.6 7.2 2.9 7.6 0.0 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) Cys_knot PF00007.17 EMC82784.1 - 6.9e-13 48.5 8.8 6.9e-13 48.5 6.1 4.0 3 1 0 4 4 4 1 Cystine-knot domain IGFBP PF00219.13 EMC82784.1 - 2.1e-12 47.3 22.8 2.1e-12 47.3 15.8 5.9 3 2 1 4 4 4 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 EMC82784.1 - 3.4e-10 39.8 7.3 3.2e-09 36.7 5.1 2.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain VWC PF00093.13 EMC82784.1 - 0.021 14.9 12.3 0.021 14.9 8.5 5.7 4 3 0 4 4 4 0 von Willebrand factor type C domain RRM_1 PF00076.17 EMC82785.1 - 5.2e-24 83.6 0.0 2.6e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82785.1 - 1.5e-13 50.4 0.0 1.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82785.1 - 4.7e-09 35.9 0.0 3e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPA_C PF08784.6 EMC82786.1 - 1.7e-23 82.9 0.3 4.5e-23 81.5 0.1 1.7 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EMC82786.1 - 0.00044 20.0 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LexA_DNA_bind PF01726.11 EMC82786.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain Baculo_VP39 PF04501.7 EMC82786.1 - 0.1 11.6 0.0 0.24 10.3 0.0 1.7 1 1 1 2 2 2 0 Baculovirus major capsid protein VP39 Metallophos PF00149.23 EMC82787.1 - 2.5e-13 49.8 0.6 3.8e-13 49.2 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase XK-related PF09815.4 EMC82788.1 - 6.6e-83 278.4 10.6 7.4e-83 278.2 7.3 1.0 1 0 0 1 1 1 1 XK-related protein TFIID_20kDa PF03847.8 EMC82789.1 - 3e-36 123.5 2.8 4.1e-36 123.0 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EMC82789.1 - 6.8e-06 26.0 0.2 1.1e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC82789.1 - 2.1e-05 24.5 0.1 3.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 EMC82789.1 - 0.00083 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF4 PF05236.9 EMC82789.1 - 0.0048 16.2 0.1 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Condensin2nSMC PF12422.3 EMC82789.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Ras PF00071.17 EMC82790.1 - 3.1e-48 163.2 0.0 3.6e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EMC82790.1 - 2.1e-11 43.3 0.0 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMC82790.1 - 2.7e-11 43.9 0.0 3.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC82790.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC82790.1 - 0.0045 16.1 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EMC82790.1 - 0.058 12.6 0.0 10 5.3 0.0 2.8 2 1 1 3 3 3 0 Ferrous iron transport protein B DUF258 PF03193.11 EMC82790.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 EMC82791.1 - 8e-42 142.3 0.0 9.5e-42 142.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC82791.1 - 3.7e-15 56.4 0.0 8.9e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC82791.1 - 1e-06 28.1 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC82791.1 - 0.00034 20.5 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC82791.1 - 0.0033 16.5 0.0 0.0068 15.5 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EMC82791.1 - 0.012 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Cytadhesin_P30 PF07271.6 EMC82792.1 - 2.4e-06 27.0 36.8 0.00049 19.4 15.3 2.0 1 1 1 2 2 2 2 Cytadhesin P30/P32 Trypan_PARP PF05887.6 EMC82792.1 - 0.051 13.3 51.7 1.5e+04 -10.2 35.8 2.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Recep_L_domain PF01030.19 EMC82794.1 - 8e-32 109.5 0.3 9.6e-32 109.2 0.2 1.1 1 0 0 1 1 1 1 Receptor L domain Pkinase_Tyr PF07714.12 EMC82797.1 - 7.5e-47 159.5 0.0 8.6e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC82797.1 - 1.9e-18 66.5 0.0 2.4e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EMC82797.1 - 0.0072 15.3 0.0 0.0093 14.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 EMC82797.1 - 0.11 10.9 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC EF-hand_6 PF13405.1 EMC82799.1 - 2.7e-11 42.3 0.5 3.1e-06 26.5 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EMC82799.1 - 6.3e-11 40.7 0.5 2.8e-05 23.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EMC82799.1 - 3.5e-06 27.0 0.0 0.028 14.5 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC82799.1 - 0.0012 18.1 1.0 0.0092 15.2 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.1 EMC82799.1 - 0.0056 16.5 0.1 0.055 13.3 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EMC82799.1 - 0.034 13.7 0.2 8.7 6.0 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain pair Caleosin PF05042.8 EMC82799.1 - 0.08 12.4 0.0 1.1 8.7 0.0 1.9 1 1 1 2 2 2 0 Caleosin related protein USP8_interact PF08941.5 EMC82800.1 - 3.6e-73 244.6 1.8 5.2e-73 244.1 1.2 1.2 1 1 0 1 1 1 1 USP8 interacting 7tm_4 PF13853.1 EMC82804.1 - 2.3e-49 166.8 6.6 2.7e-49 166.6 4.6 1.1 1 0 0 1 1 1 1 Olfactory receptor DUF2269 PF10027.4 EMC82804.1 - 0.044 13.5 2.3 1.1 8.9 1.4 2.1 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF4544 PF15077.1 EMC82805.1 - 1.8e-14 53.8 0.2 1.9e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4544) UDPGT PF00201.13 EMC82807.1 - 1.2e-78 264.9 0.0 1.4e-78 264.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 EMC82808.1 - 1.6e-39 135.7 0.0 1.8e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 EMC82809.1 - 2.2e-37 128.7 0.0 2.4e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 EMC82810.1 - 1.7e-75 254.5 0.0 2.1e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 EMC82811.1 - 7.9e-78 262.2 0.1 8.8e-78 262.0 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_2 PF13477.1 EMC82811.1 - 0.0035 17.1 0.1 2.9 7.7 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase 4-like SurE PF01975.12 EMC82811.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Survival protein SurE UDPGT PF00201.13 EMC82812.1 - 2.3e-73 247.4 0.0 2.6e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_2 PF13477.1 EMC82812.1 - 0.037 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like P22_AR_N PF10547.4 EMC82812.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 P22_AR N-terminal domain UDPGT PF00201.13 EMC82813.1 - 9.5e-211 700.6 0.1 1.1e-210 700.4 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMC82813.1 - 2.1e-06 27.5 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EMC82813.1 - 3.5e-06 26.4 0.0 0.00019 20.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 1 Prominin PF05478.6 EMC82813.1 - 0.00092 16.8 0.2 0.0013 16.3 0.1 1.2 1 0 0 1 1 1 1 Prominin Apc4_WD40 PF12894.2 EMC82813.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SurE PF01975.12 EMC82813.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Survival protein SurE UCH PF00443.24 EMC82814.1 - 1.8e-47 161.7 0.2 3.1e-41 141.2 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC82814.1 - 4.8e-25 88.6 0.1 1.3e-24 87.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YukD PF08817.5 EMC82814.1 - 0.011 16.2 0.1 1.2 9.7 0.0 3.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD Thioredoxin_7 PF13899.1 EMC82815.1 - 8.4e-25 86.6 0.0 1.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC82815.1 - 0.0097 16.0 0.0 0.026 14.7 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 EMC82815.1 - 0.038 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF4174 PF13778.1 EMC82815.1 - 0.052 13.6 0.1 0.55 10.3 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Ank_2 PF12796.2 EMC82816.1 - 1.2e-47 160.1 0.7 2.8e-21 75.6 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC82816.1 - 3.1e-29 99.2 5.5 5.6e-08 32.2 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EMC82816.1 - 4.1e-22 77.6 5.9 4.3e-08 33.1 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC82816.1 - 3.8e-20 69.9 3.1 1.4e-05 24.8 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EMC82816.1 - 3.5e-15 56.0 1.0 2.1e-09 37.6 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC82816.1 - 4.1e-11 42.5 2.8 7.4e-11 41.7 1.9 1.4 1 0 0 1 1 1 1 SOCS box HLH PF00010.21 EMC82818.1 - 3.1e-17 61.9 0.6 6.1e-17 61.0 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Toxin_trans PF07952.7 EMC82818.1 - 0.0091 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain RNA_pol_I_A49 PF06870.7 EMC82818.1 - 0.039 12.5 0.7 0.053 12.0 0.5 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Hist_deacetyl PF00850.14 EMC82819.1 - 3.3e-92 309.1 0.0 3.3e-92 309.1 0.0 2.6 3 0 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.3 EMC82819.1 - 1.5e-35 121.0 46.0 1.5e-35 121.0 31.9 3.9 2 1 1 3 3 3 1 Glutamine rich N terminal domain of histone deacetylase 4 Arb2 PF09757.4 EMC82819.1 - 0.0074 15.7 0.1 0.0074 15.7 0.1 2.0 2 0 0 2 2 2 1 Arb2 domain dNK PF01712.14 EMC82820.1 - 1.5e-22 80.0 0.1 2.3e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 EMC82820.1 - 3.5e-05 23.2 0.5 0.00016 21.1 0.4 2.2 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 EMC82820.1 - 0.00047 20.9 0.1 0.0024 18.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain SKI PF01202.17 EMC82820.1 - 0.00073 19.4 0.1 0.37 10.6 0.1 2.7 3 0 0 3 3 3 2 Shikimate kinase Cytidylate_kin2 PF13189.1 EMC82820.1 - 0.0028 17.5 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.1 EMC82820.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMC82820.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMC82820.1 - 0.044 14.0 0.5 15 5.8 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 EMC82820.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PAS_3 PF08447.6 EMC82821.1 - 5.5e-17 61.6 0.1 4.4e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 EMC82821.1 - 2.6e-11 43.4 0.0 2.8e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EMC82821.1 - 5.8e-08 32.5 0.0 1.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold HLH PF00010.21 EMC82821.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EMC82821.1 - 0.0013 19.0 0.0 1.7 9.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EMC82822.1 - 4.5e-12 45.9 0.0 8.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EMC82822.1 - 4.6e-09 36.2 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EMC82822.1 - 0.0037 17.0 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EMC82822.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain Adaptin_N PF01602.15 EMC82823.1 - 0.0098 14.2 0.0 0.011 14.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EMC82823.1 - 0.022 15.0 0.0 0.079 13.2 0.0 1.8 1 1 1 2 2 2 0 HEAT repeats DUF3037 PF11236.3 EMC82823.1 - 0.024 14.6 0.0 0.39 10.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) HEAT PF02985.17 EMC82823.1 - 0.038 14.0 2.9 1.7 8.9 0.0 3.2 4 0 0 4 4 4 0 HEAT repeat Plexin_cytopl PF08337.7 EMC82824.1 - 9.1e-261 865.8 2.7 1.1e-260 865.5 1.9 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 EMC82824.1 - 4.8e-43 145.0 3.9 2.4e-13 49.9 0.1 6.1 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 EMC82824.1 - 5.6e-23 80.8 58.0 1.3e-10 41.2 10.4 3.6 3 0 0 3 3 3 3 Plexin repeat DUF948 PF06103.6 EMC82824.1 - 0.011 15.5 0.3 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MTS PF05175.9 EMC82824.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain IncA PF04156.9 EMC82824.1 - 0.031 13.8 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 IncA protein UPF0104 PF03706.8 EMC82824.1 - 0.44 9.7 0.0 0.69 9.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Sema PF01403.14 EMC82825.1 - 2.3e-52 177.9 0.0 2.9e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Sema domain Imm31 PF15595.1 EMC82825.1 - 0.072 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 31 DUF737 PF05300.6 EMC82826.1 - 3.5e-37 128.1 21.5 3.9e-37 128.0 14.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF737) DNA_photolyase PF00875.13 EMC82826.1 - 0.011 15.4 1.5 0.011 15.4 1.0 1.1 1 0 0 1 1 1 0 DNA photolyase DUF3287 PF11690.3 EMC82826.1 - 0.061 13.3 4.9 0.071 13.1 2.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) ECH_C PF13766.1 EMC82826.1 - 0.074 13.2 1.1 0.1 12.7 0.7 1.3 1 1 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Jnk-SapK_ap_N PF09744.4 EMC82826.1 - 0.17 11.8 8.9 0.21 11.6 6.2 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2570 PF10828.3 EMC82826.1 - 0.23 11.0 7.1 0.095 12.3 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) T2SM PF04612.7 EMC82826.1 - 0.33 10.7 4.0 0.38 10.5 2.8 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M HAUS6_N PF14661.1 EMC82826.1 - 0.34 10.2 9.2 0.39 10.0 6.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Tho2 PF11262.3 EMC82826.1 - 0.42 9.6 5.2 0.46 9.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2852 PF11014.3 EMC82826.1 - 0.43 10.5 8.7 0.51 10.3 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) Arc_PepC_II PF06847.6 EMC82826.1 - 2.5 8.5 4.3 4.6 7.7 1.2 2.0 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II APG6 PF04111.7 EMC82826.1 - 3.9 6.4 13.4 4.1 6.3 9.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Ets PF00178.17 EMC82827.1 - 3.9e-33 113.4 1.6 3.9e-33 113.4 1.1 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 EMC82827.1 - 5.1e-27 93.4 0.0 8.5e-27 92.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HSF_DNA-bind PF00447.12 EMC82827.1 - 0.02 15.0 0.1 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 HSF-type DNA-binding SAM_1 PF00536.25 EMC82827.1 - 0.049 13.7 0.7 0.15 12.2 0.5 1.8 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) PARP PF00644.15 EMC82828.1 - 4.2e-41 140.6 0.6 9.2e-41 139.5 0.4 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 EMC82828.1 - 1.2e-07 30.9 4.2 3.7e-07 29.4 0.7 3.0 2 1 0 2 2 2 1 WWE domain TPR_14 PF13428.1 EMC82829.1 - 1.2e-06 28.6 0.0 0.87 10.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC82829.1 - 0.00022 21.4 0.2 5.9 7.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMC82829.1 - 0.00071 19.1 1.5 10 5.8 0.0 4.5 5 0 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 EMC82829.1 - 0.0014 18.3 5.0 6.5 6.9 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC82829.1 - 0.0037 17.1 0.2 5.4 7.0 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC82829.1 - 0.61 10.0 5.2 13 5.8 0.2 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PKD_channel PF08016.7 EMC82830.1 - 1.3e-107 359.8 11.6 1.3e-107 359.8 8.0 1.7 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.10 EMC82830.1 - 8.6e-96 320.9 1.9 1.3e-95 320.2 1.3 1.3 1 0 0 1 1 1 1 REJ domain PLAT PF01477.18 EMC82830.1 - 1.6e-19 70.3 0.4 8.1e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 PLAT/LH2 domain Ion_trans PF00520.26 EMC82830.1 - 2e-06 27.2 23.0 2e-06 27.2 15.9 3.5 3 0 0 3 3 3 1 Ion transport protein GPS PF01825.16 EMC82830.1 - 0.00096 19.2 0.3 0.00096 19.2 0.2 2.3 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain C6_DPF PF10170.4 EMC82831.1 - 1.1e-50 169.6 4.7 1.3e-50 169.3 3.3 1.1 1 0 0 1 1 1 1 Cysteine-rich domain zf-met PF12874.2 EMC82831.1 - 1.2 9.4 4.5 27 5.1 1.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYVE PF01363.16 EMC82831.1 - 7.2 6.5 9.0 7.4 6.5 4.7 2.2 2 1 0 2 2 2 0 FYVE zinc finger zf-C4 PF00105.13 EMC82832.1 - 1e-28 99.3 16.1 1.9e-28 98.4 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC82832.1 - 2.2e-26 92.2 0.1 4.1e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor wnt PF00110.14 EMC82833.1 - 2.1e-126 421.3 27.3 2.4e-126 421.1 18.9 1.0 1 0 0 1 1 1 1 wnt family Atx10homo_assoc PF09759.4 EMC82834.1 - 6.5e-40 135.0 9.3 4.5e-38 129.0 0.3 3.6 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain DUF484 PF04340.7 EMC82834.1 - 0.0036 16.8 0.4 0.0036 16.8 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF484 HEAT_2 PF13646.1 EMC82834.1 - 0.0056 16.9 1.0 0.14 12.4 0.0 3.1 4 0 0 4 4 4 1 HEAT repeats EGF_CA PF07645.10 EMC82835.1 - 2.5e-68 225.8 140.7 2.5e-11 43.3 3.6 10.7 11 1 1 12 12 12 9 Calcium-binding EGF domain cEGF PF12662.2 EMC82835.1 - 9.1e-57 188.2 71.8 5.2e-09 35.5 2.2 9.8 9 0 0 9 9 9 8 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EMC82835.1 - 1.4e-29 101.8 131.3 7.6e-07 29.1 6.3 10.9 10 1 0 10 10 10 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EMC82835.1 - 1.1e-11 44.4 113.9 0.00035 20.4 4.3 10.5 10 0 0 10 10 10 9 EGF domain ANATO PF01821.13 EMC82835.1 - 6.5e-10 38.9 18.9 1.5e-06 28.2 4.1 9.9 10 1 0 10 10 10 4 Anaphylotoxin-like domain EGF PF00008.22 EMC82835.1 - 2.3e-07 30.6 108.2 0.0028 17.5 2.7 11.5 9 1 2 11 11 11 7 EGF-like domain RIB43A PF05914.7 EMC82836.1 - 1.6e-129 431.8 58.0 1.8e-129 431.6 40.2 1.0 1 0 0 1 1 1 1 RIB43A SIR2_2 PF13289.1 EMC82837.1 - 8.7e-18 64.5 0.1 2.1e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 SIR2-like domain Uroplakin_II PF07353.7 EMC82838.1 - 0.00016 21.0 0.0 0.00028 20.3 0.0 1.5 1 0 0 1 1 1 1 Uroplakin II DUF2045 PF09741.4 EMC82839.1 - 1.1e-118 394.5 3.0 1.4e-118 394.2 2.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) NUP50 PF08911.6 EMC82840.1 - 1.5e-26 92.5 1.1 1.5e-26 92.5 0.7 2.8 3 0 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 EMC82840.1 - 1.1e-10 41.6 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Spc42p PF11544.3 EMC82841.1 - 0.024 14.5 0.3 0.034 14.0 0.2 1.2 1 0 0 1 1 1 0 Spindle pole body component Spc42p PHD PF00628.24 EMC82842.1 - 2.4e-07 30.3 7.0 5.1e-07 29.2 4.9 1.6 1 0 0 1 1 1 1 PHD-finger RAI1 PF08652.6 EMC82842.1 - 0.1 12.4 1.4 0.38 10.5 0.8 2.1 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Prok-RING_1 PF14446.1 EMC82842.1 - 0.33 10.7 8.0 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CRAL_TRIO_2 PF13716.1 EMC82843.1 - 4.2e-38 130.5 3.6 7.3e-38 129.8 2.5 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EMC82843.1 - 3.6e-29 101.3 0.0 5.2e-28 97.5 0.0 2.5 1 1 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EMC82843.1 - 3.8e-13 49.2 0.5 7.8e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain RRM_1 PF00076.17 EMC82847.1 - 4.5e-12 45.4 0.0 9.1e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82847.1 - 1.6e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82847.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.21 EMC82848.1 - 2e-25 88.8 0.8 3.4e-25 88.0 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC82848.1 - 1.5e-24 85.8 0.1 3.2e-24 84.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF281 PF03436.8 EMC82848.1 - 0.041 13.9 0.2 0.15 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF281) ADH_zinc_N_2 PF13602.1 EMC82848.1 - 0.044 14.6 0.0 0.089 13.6 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF2249 PF10006.4 EMC82848.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) An_peroxidase PF03098.10 EMC82849.1 - 6.8e-138 460.3 0.0 9.8e-138 459.8 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.7 EMC82849.1 - 6.7e-31 107.2 0.2 3.1e-29 101.9 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMC82849.1 - 1.2e-19 70.1 0.0 3.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMC82849.1 - 1.1e-17 64.2 15.5 3.4e-17 62.6 10.7 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.27 EMC82849.1 - 2.5e-14 51.4 5.5 7.1e-07 28.0 0.4 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC82849.1 - 4.7e-10 38.4 5.2 0.00069 19.2 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EMC82849.1 - 1.1e-09 37.7 8.4 0.00011 21.7 0.2 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 EMC82849.1 - 1.8e-09 37.5 7.6 0.00013 22.0 1.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC82849.1 - 1.3e-07 30.5 2.2 0.0047 16.2 0.2 3.0 2 0 0 2 2 2 2 EF hand NAD_binding_1 PF00175.16 EMC82849.1 - 9.5e-06 26.1 0.8 0.023 15.2 0.0 3.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMC82849.1 - 0.0057 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DuoxA PF10204.4 EMC82850.1 - 1.3e-112 375.4 8.4 1.5e-112 375.2 5.8 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor DUF2371 PF10177.4 EMC82850.1 - 0.59 10.0 3.3 6.2 6.6 0.0 2.8 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DuoxA PF10204.4 EMC82851.1 - 8.9e-98 326.7 4.1 1.2e-97 326.3 2.9 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Neurensin PF14927.1 EMC82851.1 - 0.42 10.0 5.8 2.9 7.2 0.1 3.2 2 1 1 3 3 3 0 Neurensin DUF3844 PF12955.2 EMC82851.1 - 0.94 9.6 2.6 1 9.4 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3844) Peptidase_S24 PF00717.18 EMC82852.1 - 2.2e-10 40.0 0.1 3.9e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like zf-C2H2 PF00096.21 EMC82853.1 - 0.13 12.6 92.0 0.38 11.1 1.3 12.3 12 0 0 12 12 12 0 Zinc finger, C2H2 type Nucleos_tra2_C PF07662.8 EMC82855.1 - 1.1e-70 237.3 7.0 2.7e-70 236.1 4.8 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EMC82855.1 - 1.4e-19 70.1 4.6 1.4e-19 70.1 3.2 3.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EMC82855.1 - 5.6e-08 32.6 10.4 5.6e-08 32.6 7.2 3.8 3 2 0 3 3 3 1 Nucleoside recognition SH2 PF00017.19 EMC82856.1 - 2.1e-16 59.5 0.0 3.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 SH2 domain YopE_N PF09020.5 EMC82857.1 - 1.5 8.8 4.2 1.6 8.7 2.9 1.0 1 0 0 1 1 1 0 YopE, N terminal 7tm_4 PF13853.1 EMC82858.1 - 9.9e-39 132.4 9.6 9.9e-39 132.4 6.6 1.9 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC82858.1 - 3.1e-33 114.9 15.5 3.8e-33 114.7 10.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC82858.1 - 0.00061 19.0 13.3 0.002 17.3 9.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2842 PF11003.3 EMC82858.1 - 7.2 6.5 9.7 8.8 6.2 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) 7tm_4 PF13853.1 EMC82859.1 - 1.6e-37 128.4 22.2 1.6e-37 128.4 15.4 2.6 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC82859.1 - 7.1e-34 117.0 29.8 9.5e-34 116.6 20.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-RING_2 PF13639.1 EMC82860.1 - 1.6e-06 27.8 0.8 1.6e-06 27.8 0.6 1.5 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.1 EMC82860.1 - 0.12 12.1 0.4 0.24 11.1 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 NACHT PF05729.7 EMC82861.1 - 8.9e-33 113.2 0.2 3.2e-32 111.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain LRR_6 PF13516.1 EMC82861.1 - 3.3e-23 79.0 1.9 0.1 12.7 0.0 9.8 9 0 0 9 9 9 6 Leucine Rich repeat CARD PF00619.16 EMC82861.1 - 1.6e-14 53.4 1.0 3.1e-13 49.3 0.1 3.2 3 0 0 3 3 3 1 Caspase recruitment domain LRR_4 PF12799.2 EMC82861.1 - 4.1e-11 42.2 0.8 0.061 12.9 0.0 4.8 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) AAA_16 PF13191.1 EMC82861.1 - 0.0017 18.4 0.0 0.0055 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain LRR_1 PF00560.28 EMC82861.1 - 0.017 15.0 0.8 27 5.3 0.4 5.1 4 2 0 4 4 4 0 Leucine Rich Repeat SpoU_sub_bind PF08032.7 EMC82861.1 - 0.024 14.7 2.6 5.5 7.2 0.0 3.9 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding FumaraseC_C PF10415.4 EMC82861.1 - 0.056 13.5 0.5 0.5 10.4 0.1 2.7 2 1 1 3 3 3 0 Fumarase C C-terminus AIG2_2 PF13772.1 EMC82862.1 - 6.3e-30 103.1 0.0 8.2e-30 102.7 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EMC82862.1 - 4.7e-07 30.2 0.0 8.5e-07 29.4 0.0 1.4 2 0 0 2 2 2 1 AIG2-like family XG_FTase PF03254.8 EMC82862.1 - 0.098 11.1 0.0 0.28 9.6 0.0 1.6 1 1 1 2 2 2 0 Xyloglucan fucosyltransferase GDA1_CD39 PF01150.12 EMC82864.1 - 3.3e-101 338.9 0.0 4e-101 338.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ribosomal_L14e PF01929.12 EMC82865.1 - 7.6e-32 109.4 9.8 1.2e-31 108.9 6.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EMC82865.1 - 0.0064 16.1 0.1 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 KOW motif DRY_EERY PF09750.4 EMC82865.1 - 0.081 13.0 1.8 0.11 12.5 1.3 1.2 1 0 0 1 1 1 0 Alternative splicing regulator DUF563 PF04577.9 EMC82866.1 - 3.5e-22 79.3 0.1 7.9e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.20 EMC82867.1 - 2.5e-73 246.4 0.0 5e-73 245.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC82867.1 - 4.5e-42 143.9 0.0 6.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC82867.1 - 4.2e-10 39.0 0.0 2.3e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC82867.1 - 0.017 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC82867.1 - 0.07 12.4 0.0 0.78 9.0 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Anoctamin PF04547.7 EMC82868.1 - 6.2e-123 410.7 23.3 7.8e-123 410.4 16.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Abhydrolase_6 PF12697.2 EMC82869.1 - 5.7e-31 108.1 0.0 6.9e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC82869.1 - 2.8e-18 66.3 0.0 2.2e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC82869.1 - 6.3e-11 42.2 0.0 1.2e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC82869.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EMC82869.1 - 0.00081 17.9 0.0 0.0026 16.2 0.0 1.7 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.8 EMC82869.1 - 0.054 13.0 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 EMC82869.1 - 0.086 11.1 0.0 0.16 10.2 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF1071 PF06378.6 EMC82869.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) FRG1 PF06229.7 EMC82870.1 - 9.1e-82 273.1 0.9 9.1e-82 273.1 0.6 1.5 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 EMC82870.1 - 2.5e-08 33.9 0.0 1.1e-07 31.8 0.0 2.0 1 1 0 2 2 2 1 Fascin domain DUF569 PF04601.8 EMC82870.1 - 0.00015 21.1 0.2 0.0016 17.8 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF569) DUF1754 PF08555.5 EMC82870.1 - 0.046 14.3 7.7 0.046 14.3 5.3 2.8 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CBAH PF02275.13 EMC82871.1 - 5.6e-38 131.1 0.2 5.3e-36 124.6 0.1 2.1 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.1 EMC82871.1 - 1.9e-34 117.8 0.1 5e-34 116.5 0.0 1.7 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HP_OMP PF01856.12 EMC82871.1 - 0.086 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein TFIIE_alpha PF02002.12 EMC82872.1 - 7.9e-28 96.0 1.4 1.4e-27 95.2 1.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 EMC82872.1 - 3.6e-23 81.2 1.2 1.1e-22 79.7 0.8 1.9 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 EMC82872.1 - 1.4e-06 27.5 0.7 3.3e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 EMC82872.1 - 0.036 13.7 0.7 0.074 12.7 0.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PyrI_C PF02748.10 EMC82872.1 - 0.11 11.9 3.6 0.17 11.3 1.5 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Elf1 PF05129.8 EMC82872.1 - 0.13 11.9 2.1 0.42 10.3 1.4 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 EMC82872.1 - 0.34 10.9 2.5 12 5.9 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 EMC82872.1 - 0.36 10.9 1.5 23 5.1 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Fibrinogen_C PF00147.13 EMC82874.1 - 1.6e-79 266.7 11.4 2e-79 266.5 7.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FUSC PF04632.7 EMC82876.1 - 0.79 8.0 1.1 1.3 7.3 0.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family I-set PF07679.11 EMC82877.1 - 7.9e-15 54.4 0.1 9.3e-09 35.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82877.1 - 2e-12 47.0 1.3 2.2e-05 24.5 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 EMC82877.1 - 3.8e-09 36.9 1.0 0.00011 22.6 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 EMC82877.1 - 2.7e-07 30.5 0.4 0.0071 16.4 0.0 4.3 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 EMC82877.1 - 0.00037 20.3 1.9 2.2 8.1 0.0 3.9 2 2 1 3 3 3 2 Immunoglobulin V-set domain AA_permease_2 PF13520.1 EMC82878.1 - 8.3e-52 176.1 30.3 8.3e-52 176.1 21.0 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 EMC82878.1 - 4.7e-36 124.1 28.2 4.7e-36 124.1 19.5 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.1 EMC82878.1 - 1.9e-24 85.2 6.1 1.9e-24 85.2 4.2 3.6 3 0 0 3 3 3 1 C-terminus of AA_permease Myotub-related PF06602.9 EMC82879.1 - 1.2e-143 478.1 0.1 1.6e-143 477.8 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 EMC82879.1 - 0.00095 18.7 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC82879.1 - 0.002 17.5 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC82879.1 - 0.0077 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Mod_r PF07200.8 EMC82880.1 - 4.9e-47 159.5 16.4 6.2e-47 159.2 11.4 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.8 EMC82880.1 - 0.00069 19.2 0.7 0.00069 19.2 0.5 2.9 4 0 0 4 4 4 1 UEV domain UQ_con PF00179.21 EMC82880.1 - 0.14 11.6 0.9 0.4 10.0 0.6 1.7 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme DivIVA PF05103.8 EMC82880.1 - 3 7.8 9.1 4.6 7.2 5.6 1.9 1 1 0 1 1 1 0 DivIVA protein CAF1 PF04857.15 EMC82881.1 - 1.7e-70 237.3 0.1 2.6e-70 236.7 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease zf-DHHC PF01529.15 EMC82882.1 - 1.6e-41 141.5 8.0 2.7e-41 140.8 5.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Spt4 PF06093.8 EMC82882.1 - 1.1 9.1 6.8 2.2 8.2 4.7 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger EF-hand_8 PF13833.1 EMC82883.1 - 1.3e-19 69.5 11.5 2.8e-11 42.8 0.0 6.1 5 2 1 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.1 EMC82883.1 - 2.5e-10 39.3 13.3 0.00025 20.6 0.3 6.8 8 0 0 8 8 8 2 EF-hand domain EF-hand_7 PF13499.1 EMC82883.1 - 5.7e-10 39.1 9.5 0.00013 21.9 0.3 5.5 5 2 0 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC82883.1 - 9.4e-10 37.0 20.2 8e-05 21.6 0.5 7.0 8 0 0 8 8 8 2 EF hand EF-hand_4 PF12763.2 EMC82883.1 - 0.004 16.8 0.5 0.043 13.5 0.0 2.8 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EMC82883.1 - 0.9 8.9 14.8 2.1 7.8 0.1 5.7 8 0 0 8 8 8 0 EF hand FGF PF00167.13 EMC82884.1 - 1.1e-31 109.0 0.0 1.3e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor SIR2 PF02146.12 EMC82884.1 - 0.085 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Sir2 family OST3_OST6 PF04756.8 EMC82886.1 - 9e-53 178.1 0.1 1.3e-52 177.5 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EMC82886.1 - 1.1e-05 24.9 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.1 EMC82886.1 - 0.004 16.5 3.3 0.072 12.4 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4131) YhhN PF07947.9 EMC82886.1 - 0.046 13.0 2.9 0.16 11.3 2.0 1.8 1 1 0 1 1 1 0 YhhN-like protein Sarcoglycan_1 PF04790.8 EMC82887.1 - 1.3e-104 349.0 0.0 1.6e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 EMC82887.1 - 2.7e-05 23.7 0.1 0.0042 16.6 0.0 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) DUF2208 PF09973.4 EMC82887.1 - 0.057 12.6 0.1 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) SR-25 PF10500.4 EMC82887.1 - 7 6.0 7.2 14 5.0 5.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 EMC82889.1 - 6.5 5.1 88.9 7.7 4.8 61.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 START PF01852.14 EMC82890.1 - 1.8e-46 158.0 0.1 3.8e-46 157.0 0.1 1.5 1 0 0 1 1 1 1 START domain RhoGAP PF00620.22 EMC82890.1 - 1.1e-41 141.9 0.6 4.2e-41 140.0 0.6 1.9 2 0 0 2 2 2 1 RhoGAP domain SAM_2 PF07647.12 EMC82890.1 - 2.1e-06 27.4 0.0 1.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Methyltransf_11 PF08241.7 EMC82891.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC82891.1 - 1.3e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC82891.1 - 6.1e-08 32.5 0.0 1.8e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC82891.1 - 2.6e-07 31.0 0.0 1.3e-06 28.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC82891.1 - 1.1e-06 27.9 0.0 2.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMC82891.1 - 1.2e-06 28.7 0.0 3.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMC82891.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 EMC82891.1 - 0.00051 19.1 0.2 0.014 14.4 0.2 2.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EMC82891.1 - 0.0088 16.6 0.0 0.047 14.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMC82891.1 - 0.01 14.5 0.0 0.1 11.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EMC82891.1 - 0.024 14.6 0.0 0.07 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain SAICAR_synt PF01259.13 EMC82892.1 - 3.7e-83 278.4 0.1 4.7e-83 278.1 0.1 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.15 EMC82892.1 - 9.5e-36 122.3 0.0 1.7e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 AIR carboxylase Myb_DNA-bind_4 PF13837.1 EMC82893.1 - 1.9e-21 75.9 3.6 2.2e-21 75.8 2.5 1.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EMC82893.1 - 4.5e-05 23.2 4.0 0.00011 21.9 2.5 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EMC82893.1 - 0.00054 20.1 2.3 0.00068 19.7 1.6 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.2 EMC82893.1 - 0.00063 20.3 2.7 0.00074 20.1 1.9 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HALZ PF02183.13 EMC82893.1 - 0.011 15.4 0.3 0.024 14.3 0.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Myb_DNA-bind_6 PF13921.1 EMC82893.1 - 0.011 15.7 2.4 0.03 14.4 1.6 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain PriCT_1 PF08708.6 EMC82893.1 - 0.031 14.1 0.1 0.058 13.2 0.0 1.6 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) Pep_deformylase PF01327.16 EMC82893.1 - 0.096 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Polypeptide deformylase Myb_DNA-bind_4 PF13837.1 EMC82894.1 - 4.5e-23 81.1 2.6 5.2e-23 80.9 1.8 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EMC82894.1 - 1.3e-05 25.0 3.9 2.7e-05 23.9 2.7 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EMC82894.1 - 0.00084 19.9 2.2 0.00096 19.7 1.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EMC82894.1 - 0.002 18.2 0.6 0.0026 17.9 0.4 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.1 EMC82894.1 - 0.0038 17.3 1.4 0.0062 16.6 0.9 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cas_CT1975 PF09344.5 EMC82894.1 - 0.017 14.5 0.5 0.017 14.5 0.3 1.0 1 0 0 1 1 1 0 CT1975-like protein Ribosomal_L18ae PF01775.12 EMC82894.1 - 0.27 11.1 2.0 0.36 10.7 1.2 1.4 1 1 0 1 1 1 0 Ribosomal L18ae/LX protein domain Myb_DNA-bind_4 PF13837.1 EMC82895.1 - 2.4e-20 72.4 1.6 3.1e-20 72.1 1.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EMC82895.1 - 0.00033 20.4 2.9 0.00076 19.3 2.0 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EMC82895.1 - 0.0014 19.2 0.8 0.0016 19.0 0.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC82895.1 - 0.0082 16.2 1.9 0.016 15.2 1.3 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain GATase_2 PF00310.16 EMC82896.1 - 4.1e-25 88.2 0.0 2.6e-24 85.6 0.0 2.0 1 1 1 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMC82896.1 - 6.6e-17 61.7 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMC82896.1 - 2e-15 56.6 0.0 3.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EMC82896.1 - 8.2e-13 48.1 0.1 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EMC82896.1 - 1.4e-07 30.4 0.0 2.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AMP-binding PF00501.23 EMC82897.1 - 2.9e-48 164.2 0.0 4e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.1 EMC82897.1 - 7.1e-35 118.2 0.2 4e-06 26.9 0.2 9.1 9 0 0 9 9 9 6 PQQ-like domain PQQ_2 PF13360.1 EMC82897.1 - 5.3e-24 84.9 0.0 6e-08 32.4 0.0 4.7 2 1 3 5 5 5 4 PQQ-like domain PQQ PF01011.16 EMC82897.1 - 1.4e-16 59.1 6.8 0.02 14.4 0.0 8.0 8 0 0 8 8 8 7 PQQ enzyme repeat AMP-binding_C PF13193.1 EMC82897.1 - 0.00024 21.9 0.0 0.00065 20.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EMC82897.1 - 0.038 14.2 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site DUF4592 PF15262.1 EMC82898.1 - 9.6e-40 136.1 1.6 9.6e-40 136.1 1.1 7.8 6 2 3 9 9 9 1 Domain of unknown function (DUF4592) Reo_sigmaC PF04582.7 EMC82899.1 - 0.00026 20.2 74.2 0.064 12.4 6.1 8.8 3 2 6 9 9 9 5 Reovirus sigma C capsid protein CCDC155 PF14662.1 EMC82899.1 - 0.0015 18.1 7.3 0.0015 18.1 5.0 9.7 3 2 6 9 9 9 1 Coiled-coil region of CCDC155 AAA_13 PF13166.1 EMC82899.1 - 0.33 9.3 133.9 0.01 14.3 13.2 6.1 2 1 4 6 6 6 0 AAA domain CENP-F_leu_zip PF10473.4 EMC82899.1 - 3 7.7 201.1 0.19 11.6 10.9 12.6 3 2 10 13 13 13 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec3_C PF09763.4 EMC82900.1 - 3.5e-217 722.8 27.1 4.5e-217 722.5 18.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EMC82900.1 - 1.1e-28 98.9 1.6 3.5e-28 97.3 1.1 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FlaC_arch PF05377.6 EMC82900.1 - 0.13 12.1 3.2 2.1 8.3 0.7 3.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EMC82900.1 - 6.3 7.2 10.3 2 8.8 1.8 3.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TLV_coat PF00429.14 EMC82901.1 - 2.4e-05 23.0 2.3 3e-05 22.7 1.6 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC82901.1 - 0.0032 17.0 2.2 0.0038 16.8 1.5 1.0 1 0 0 1 1 1 1 Retroviral envelope protein HXXEE PF13787.1 EMC82901.1 - 0.013 15.8 0.2 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif Phlebovirus_G2 PF07245.6 EMC82901.1 - 0.015 13.6 0.6 0.014 13.6 0.4 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 DUF2976 PF11190.3 EMC82901.1 - 0.53 9.8 4.0 1 8.9 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) NMU PF02070.10 EMC82902.1 - 5.6e-11 41.7 0.9 1.5e-10 40.4 0.6 1.7 1 0 0 1 1 1 1 Neuromedin U Phosducin PF02114.11 EMC82903.1 - 6.3e-18 64.4 0.2 1.4e-17 63.3 0.1 1.5 1 1 1 2 2 2 1 Phosducin Thioredoxin PF00085.15 EMC82903.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin HLH PF00010.21 EMC82904.1 - 3.4e-10 39.4 0.8 7.5e-10 38.3 0.4 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS PF00989.19 EMC82904.1 - 2.3e-08 33.7 0.1 1.7e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EMC82904.1 - 0.00092 19.5 0.1 0.01 16.1 0.0 2.4 2 1 1 3 3 3 1 PAS domain RNA_pol_Rpb4 PF03874.11 EMC82904.1 - 0.039 13.9 1.2 0.11 12.5 0.4 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb4 PAS_11 PF14598.1 EMC82904.1 - 0.051 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 PAS domain GATase_2 PF00310.16 EMC82904.1 - 0.14 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Phage_Gp23 PF10669.4 EMC82904.1 - 0.17 12.0 2.3 0.27 11.3 1.6 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) PAS_11 PF14598.1 EMC82905.1 - 8.7e-23 80.4 0.0 8.7e-23 80.4 0.0 3.5 3 1 0 3 3 3 1 PAS domain PAS_3 PF08447.6 EMC82905.1 - 2.2e-15 56.4 0.6 8.7e-15 54.5 0.1 2.2 2 0 0 2 2 2 1 PAS fold UPF0016 PF01169.14 EMC82906.1 - 2.6e-43 146.0 20.3 3.7e-24 84.6 2.8 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Med9 PF07544.8 EMC82906.1 - 0.26 11.0 1.9 0.41 10.4 1.3 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EMC82906.1 - 0.75 9.3 0.0 0.75 9.3 0.0 2.5 3 0 0 3 3 3 0 IncA protein Steroid_dh PF02544.11 EMC82907.1 - 6.8e-24 84.3 7.0 1.2e-23 83.4 4.6 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FB_lectin PF07367.6 EMC82907.1 - 0.0034 16.9 0.1 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal fruit body lectin Pkinase_Tyr PF07714.12 EMC82908.1 - 1.2e-101 339.1 0.0 2e-101 338.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.11 EMC82908.1 - 9.2e-53 176.0 6.4 1.3e-15 56.9 0.0 7.2 6 1 0 6 6 6 6 Immunoglobulin I-set domain Pkinase PF00069.20 EMC82908.1 - 4.9e-45 153.7 0.0 2.4e-32 112.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.1 EMC82908.1 - 4.2e-43 145.3 16.5 1e-08 35.1 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 EMC82908.1 - 3.9e-32 110.5 13.7 6e-09 36.2 0.1 7.4 6 1 0 6 6 6 5 Immunoglobulin domain ig PF00047.20 EMC82908.1 - 2.9e-23 81.7 12.1 1.9e-09 37.4 0.0 7.5 6 1 0 6 6 6 4 Immunoglobulin domain V-set PF07686.12 EMC82908.1 - 7.2e-18 64.5 12.2 1.1e-05 25.2 0.0 7.7 4 3 2 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC82908.1 - 2e-08 33.9 5.2 0.00083 19.2 0.0 4.8 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.1 EMC82908.1 - 0.11 11.3 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 EMC82909.1 - 1.5e-104 348.6 0.0 2.2e-104 348.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC82909.1 - 3.9e-44 150.7 0.0 1.5e-30 106.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 EMC82909.1 - 2.6e-24 84.8 3.8 1.7e-09 37.4 0.0 5.6 5 1 1 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82909.1 - 6.5e-21 74.2 4.0 6.1e-06 26.2 0.0 5.2 4 1 1 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 EMC82909.1 - 1.6e-12 47.7 12.0 2e-05 24.9 0.1 5.1 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 EMC82909.1 - 1.9e-05 24.4 10.9 0.074 12.9 0.1 6.0 6 2 0 6 6 6 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC82909.1 - 0.00046 20.0 0.3 0.32 10.9 0.0 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC82909.1 - 0.12 12.4 0.1 0.12 12.4 0.1 4.5 5 0 0 5 5 5 0 Immunoglobulin domain APH PF01636.18 EMC82909.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_E3 PF06040.6 EMC82909.1 - 2.7 7.9 8.3 13 5.7 4.4 2.5 2 0 0 2 2 2 0 Adenovirus E3 protein Pkinase_Tyr PF07714.12 EMC82910.1 - 1.8e-104 348.4 0.0 3.1e-104 347.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC82910.1 - 7.5e-45 153.0 0.0 3.5e-29 101.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 EMC82910.1 - 1.1e-20 73.2 7.1 4.4e-08 32.8 0.3 5.0 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC82910.1 - 1.3e-19 70.0 6.7 2e-06 27.8 0.0 5.6 5 1 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 EMC82910.1 - 5.4e-14 52.4 7.4 0.0012 19.3 0.1 6.1 5 2 0 5 5 5 4 Immunoglobulin domain ig PF00047.20 EMC82910.1 - 6.1e-09 35.8 17.5 0.00047 20.2 0.0 5.7 6 1 0 6 6 6 2 Immunoglobulin domain V-set PF07686.12 EMC82910.1 - 0.00013 21.8 6.2 0.71 9.7 0.0 4.8 5 1 0 5 5 5 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 EMC82910.1 - 0.00019 19.8 4.7 3.5 5.7 0.0 4.3 3 1 1 4 4 4 3 Alphaherpesvirus glycoprotein E Gypsy PF07253.6 EMC82910.1 - 0.011 14.0 0.1 1.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Gypsy protein C2-set_2 PF08205.7 EMC82910.1 - 0.014 15.2 1.8 2.6 7.9 0.0 4.4 5 0 0 5 5 5 0 CD80-like C2-set immunoglobulin domain Homeobox PF00046.24 EMC82911.1 - 2.4e-22 78.3 4.5 5.2e-22 77.2 3.1 1.6 1 0 0 1 1 1 1 Homeobox domain Terminase_5 PF06056.7 EMC82911.1 - 0.014 14.9 0.6 0.057 12.9 0.1 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Phage_terminase PF10668.4 EMC82911.1 - 0.092 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Phage terminase small subunit Homeobox_KN PF05920.6 EMC82911.1 - 0.23 11.1 1.4 0.39 10.4 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain Erf4 PF10256.4 EMC82912.1 - 1.7e-25 89.1 0.1 2.3e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PDZ PF00595.19 EMC82913.1 - 3e-63 209.9 3.8 8.4e-17 61.1 0.0 4.4 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC82913.1 - 1.4e-19 69.7 0.0 0.00061 19.6 0.0 4.3 4 0 0 4 4 4 4 PDZ domain Tricorn_PDZ PF14685.1 EMC82913.1 - 8.2e-06 25.5 0.1 1.9 8.3 0.0 4.3 4 0 0 4 4 4 2 Tricorn protease PDZ domain zf-C3HC4 PF00097.20 EMC82913.1 - 5.8e-05 22.6 6.5 0.00016 21.2 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC82913.1 - 0.00025 20.8 7.0 0.0008 19.1 4.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EMC82913.1 - 0.00076 19.3 8.0 0.0026 17.6 5.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMC82913.1 - 0.00085 19.3 6.1 0.0029 17.5 4.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC82913.1 - 0.0037 16.9 4.8 0.0037 16.9 3.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC82913.1 - 0.011 15.7 3.4 0.054 13.6 2.3 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC82913.1 - 0.016 14.8 2.8 0.016 14.8 2.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC82913.1 - 0.43 10.3 6.3 1.6 8.5 4.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Fip1 PF05182.8 EMC82914.1 - 4.1e-26 89.9 1.0 8.9e-26 88.9 0.7 1.6 1 0 0 1 1 1 1 Fip1 motif Ras PF00071.17 EMC82915.1 - 4.8e-18 65.0 0.0 6.6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC82915.1 - 2.3e-09 37.7 0.0 4.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF2819 PF10995.3 EMC82915.1 - 0.018 13.8 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) MMR_HSR1 PF01926.18 EMC82915.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase UCH PF00443.24 EMC82916.1 - 1.5e-68 230.8 8.5 1.7e-68 230.6 5.9 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC82916.1 - 2.3e-36 125.7 8.4 2.8e-36 125.4 5.8 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sarcoglycan_1 PF04790.8 EMC82918.1 - 2.3e-75 253.1 0.4 2.8e-75 252.9 0.3 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein LRR_8 PF13855.1 EMC82919.1 - 4.1e-27 93.7 21.6 5.9e-12 45.1 0.3 4.5 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EMC82919.1 - 1.2e-16 59.8 22.2 9.3e-07 28.3 0.3 5.6 4 1 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC82919.1 - 8.5e-12 43.3 20.7 0.057 13.4 1.0 8.3 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.1 EMC82919.1 - 1.3e-09 37.1 17.9 0.18 11.9 0.1 6.9 7 1 1 8 8 8 4 Leucine Rich repeat LRR_5 PF13306.1 EMC82919.1 - 1.4e-07 31.3 0.3 4.3e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC82919.1 - 4.4e-05 23.0 13.4 8.6 7.0 0.1 7.2 8 0 0 8 8 8 1 Leucine rich repeat LRR_9 PF14580.1 EMC82919.1 - 0.0057 16.2 3.2 1.3 8.5 0.2 2.4 2 1 0 2 2 2 2 Leucine-rich repeat TAT_ubiq PF07706.7 EMC82919.1 - 0.033 14.1 0.6 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Aminotransferase ubiquitination site Phage_T7_tail PF03906.9 EMC82919.1 - 0.095 12.3 0.1 6.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Phage T7 tail fibre protein Cullin_binding PF03556.10 EMC82920.1 - 2.6e-33 114.6 1.3 4.6e-33 113.8 0.9 1.4 1 0 0 1 1 1 1 Cullin binding HCV_NS4a PF01006.15 EMC82921.1 - 0.75 9.3 5.6 0.63 9.6 0.0 2.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a OCIA PF07051.6 EMC82922.1 - 2.1e-33 114.0 0.5 2.4e-33 113.8 0.3 1.0 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) GLTT PF01744.15 EMC82922.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 GLTT repeat (6 copies) OCIA PF07051.6 EMC82923.1 - 3.9e-32 109.9 0.0 6.6e-32 109.1 0.0 1.4 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) Peptidase_C7 PF01830.13 EMC82924.1 - 0.25 10.4 4.2 16 4.5 0.0 3.7 1 1 4 5 5 5 0 Peptidase C7 family MOR2-PAG1_N PF14222.1 EMC82925.1 - 7.2e-169 563.0 3.9 1.2e-168 562.2 2.7 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EMC82925.1 - 7.5e-73 245.5 7.1 7.5e-73 245.5 4.9 2.7 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EMC82925.1 - 1.2e-39 135.8 13.8 5.8e-15 54.0 0.1 6.2 6 0 0 6 6 6 6 Cell morphogenesis central region SLAIN PF15301.1 EMC82926.1 - 4.5e-135 450.5 37.2 5.1e-135 450.3 25.8 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family Pkinase_Tyr PF07714.12 EMC82927.1 - 2e-95 318.7 0.2 2.9e-95 318.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC82927.1 - 6.1e-49 166.4 0.0 8.9e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.23 EMC82927.1 - 1.8e-16 59.2 0.4 8.2e-16 57.1 0.2 2.3 3 0 0 3 3 3 1 SH3 domain PH PF00169.24 EMC82927.1 - 1e-15 57.7 1.1 2.4e-12 46.9 0.2 2.4 2 0 0 2 2 2 2 PH domain SH2 PF00017.19 EMC82927.1 - 1.6e-15 56.6 0.1 4.5e-15 55.2 0.1 1.8 1 0 0 1 1 1 1 SH2 domain BTK PF00779.14 EMC82927.1 - 2.5e-13 49.3 1.3 5e-13 48.4 0.9 1.5 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.1 EMC82927.1 - 5.9e-11 41.7 0.1 1.5e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC82927.1 - 3e-08 33.0 0.1 6.6e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC82927.1 - 0.00024 21.2 1.1 0.0028 17.8 0.4 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Kinase-like PF14531.1 EMC82927.1 - 0.00079 18.4 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 EMC82928.1 - 2.3e-96 321.8 0.1 2.9e-96 321.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC82928.1 - 1.7e-52 178.1 0.0 2.6e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC82928.1 - 1.5e-19 69.5 0.5 3.3e-19 68.4 0.3 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC82928.1 - 1.2e-15 56.5 0.2 5.4e-15 54.5 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC82928.1 - 1.3e-07 31.1 0.1 3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC82928.1 - 0.00035 20.0 0.0 0.001 18.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 EMC82928.1 - 0.0035 16.3 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH2_2 PF14633.1 EMC82928.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 SH2 domain DUF2509 PF10713.4 EMC82928.1 - 0.047 13.4 0.9 0.092 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) APH PF01636.18 EMC82928.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mg_trans_NIPA PF05653.9 EMC82929.1 - 1.7e-129 431.0 17.9 2.2e-129 430.7 12.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMC82929.1 - 1.2e-08 35.1 1.5 1.2e-08 35.1 1.1 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC82929.1 - 2.2e-08 34.1 5.2 2.2e-08 34.1 3.6 4.4 3 1 1 4 4 4 1 EamA-like transporter family Ion_trans PF00520.26 EMC82930.1 - 7.5e-19 67.7 2.9 1.2e-18 67.0 2.0 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 EMC82930.1 - 3.7e-17 61.9 0.0 6.4e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2413 PF10310.4 EMC82930.1 - 0.0016 17.3 5.3 0.0027 16.6 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) HrpB7 PF09486.5 EMC82930.1 - 0.015 15.2 0.6 0.47 10.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ion_trans_2 PF07885.11 EMC82930.1 - 0.024 14.3 3.9 0.079 12.6 2.7 2.0 1 0 0 1 1 1 0 Ion channel Zip PF02535.17 EMC82930.1 - 0.058 12.3 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EMC82930.1 - 0.075 11.0 8.1 0.05 11.6 4.0 1.7 2 0 0 2 2 2 0 CDC45-like protein DUF3464 PF11947.3 EMC82930.1 - 0.16 11.4 6.3 0.34 10.3 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RR_TM4-6 PF06459.7 EMC82930.1 - 0.36 10.6 12.4 0.069 13.0 6.0 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 EMC82930.1 - 0.75 8.4 22.8 1.5 7.4 15.8 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 IncA PF04156.9 EMC82930.1 - 1.2 8.7 9.4 0.86 9.1 1.1 2.3 2 0 0 2 2 2 0 IncA protein zf-NF-X1 PF01422.12 EMC82931.1 - 9.7e-11 41.4 283.0 1.2e-05 25.1 9.1 18.4 18 0 0 18 18 18 12 NF-X1 type zinc finger Trypsin PF00089.21 EMC82932.1 - 8.5e-63 211.8 0.0 2.1e-62 210.6 0.0 1.7 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 EMC82932.1 - 2.9e-59 196.6 146.0 2.1e-10 40.2 8.2 9.7 9 1 0 9 9 9 7 Low-density lipoprotein receptor domain class A Fz PF01392.17 EMC82932.1 - 9.6e-52 174.2 20.0 9.2e-31 106.6 4.6 5.7 4 2 2 6 6 6 2 Fz domain Hydrolase PF00702.21 EMC82933.1 - 6.6e-16 59.3 0.0 3.1e-11 44.0 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC82933.1 - 3.4e-15 56.7 0.0 3e-14 53.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC82933.1 - 1.7e-09 37.4 0.0 5.5e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EMC82933.1 - 3.4e-09 36.0 0.2 1.9e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EMC82933.1 - 0.0026 17.3 3.7 0.0052 16.4 0.4 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC82933.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase 23S_rRNA_IVP PF05635.6 EMC82933.1 - 0.026 14.4 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein HCaRG PF07258.9 EMC82934.1 - 8.7e-30 103.5 0.9 1e-29 103.3 0.6 1.0 1 0 0 1 1 1 1 HCaRG protein FliG_C PF01706.11 EMC82934.1 - 0.2 11.6 2.0 0.39 10.7 0.3 2.1 1 1 1 2 2 2 0 FliG C-terminal domain Neur_chan_memb PF02932.11 EMC82935.1 - 1.1e-52 179.2 2.0 5.2e-52 177.1 1.4 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC82935.1 - 7.6e-40 136.3 0.0 1.3e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC82936.1 - 5.5e-53 180.2 3.1 1.1e-52 179.3 2.2 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC82936.1 - 1.5e-50 171.3 0.0 2.1e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4396 PF14342.1 EMC82936.1 - 1.2 9.2 8.4 2 8.5 1.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Neur_chan_LBD PF02931.18 EMC82937.1 - 6.1e-52 175.9 0.0 9e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC82937.1 - 3.5e-45 154.7 9.4 3.4e-36 125.3 4.8 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 EMC82938.1 - 4.2e-48 164.3 4.4 1.2e-41 143.1 0.7 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC82938.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Glucosamine_iso PF01182.15 EMC82939.1 - 4.6e-23 81.9 0.0 6.7e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GTP_EFTU PF00009.22 EMC82940.1 - 3.2e-52 176.7 0.3 4.6e-52 176.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EMC82940.1 - 1.1e-46 157.1 1.9 1.9e-46 156.3 0.7 1.9 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EMC82940.1 - 6.8e-20 70.7 0.0 2.7e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus Ras PF00071.17 EMC82940.1 - 2.8e-07 30.0 0.1 4.8e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EMC82940.1 - 1.6e-06 28.0 0.1 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EMC82940.1 - 1.8e-06 27.9 0.2 4.4e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMC82940.1 - 6.5e-06 25.9 0.0 2.6e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EMC82940.1 - 0.0015 17.8 0.0 0.0038 16.4 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 EMC82940.1 - 0.024 13.6 0.8 0.21 10.5 0.0 2.2 2 0 0 2 2 2 0 Septin BTB_2 PF02214.17 EMC82941.1 - 7.9e-16 58.0 0.0 1.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glutaredoxin PF00462.19 EMC82942.1 - 1.5e-10 40.9 0.1 3.4e-09 36.5 0.1 2.2 2 0 0 2 2 2 1 Glutaredoxin E1-E2_ATPase PF00122.15 EMC82943.1 - 1.6e-21 76.3 0.0 3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMC82943.1 - 8.5e-17 61.9 0.3 2e-16 60.7 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC82943.1 - 9.3e-13 47.9 0.0 3.4e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EMC82943.1 - 5.4e-12 46.5 0.0 4.6e-11 43.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC82943.1 - 0.0002 21.0 0.3 0.009 15.6 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3590 PF12148.3 EMC82943.1 - 0.1 12.2 0.2 0.23 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3590) Shisa PF13908.1 EMC82944.1 - 2.5e-14 53.8 1.2 3.5e-14 53.3 0.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3446 PF11928.3 EMC82944.1 - 0.023 14.8 6.5 0.043 14.0 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) BEN PF10523.4 EMC82945.1 - 7.7e-12 45.0 0.0 1.8e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 BEN domain Leu_zip PF15294.1 EMC82945.1 - 0.0027 16.8 2.7 0.011 14.9 0.1 2.1 2 0 0 2 2 2 1 Leucine zipper bZIP_1 PF00170.16 EMC82945.1 - 0.0054 16.6 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor Cep57_CLD_2 PF14197.1 EMC82945.1 - 0.02 14.8 0.5 0.089 12.7 0.1 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 NYD-SP28_assoc PF14775.1 EMC82945.1 - 0.031 13.9 1.6 0.075 12.7 1.1 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 EMC82945.1 - 0.043 13.6 3.8 0.1 12.4 2.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Uds1 PF15456.1 EMC82945.1 - 0.05 13.5 0.6 0.18 11.7 0.4 1.9 1 1 0 1 1 1 0 Up-regulated During Septation Thioredoxin_2 PF13098.1 EMC82945.1 - 0.053 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Shugoshin_N PF07558.6 EMC82945.1 - 0.096 12.4 1.5 0.2 11.3 1.0 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region zf-C4pol PF14260.1 EMC82945.1 - 2.3 8.2 6.6 0.43 10.6 0.8 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Cation_efflux PF01545.16 EMC82946.1 - 1.2e-41 142.6 1.1 1.2e-41 142.6 0.8 1.4 2 0 0 2 2 2 1 Cation efflux family DUF1319 PF07028.6 EMC82946.1 - 0.022 14.9 0.4 0.048 13.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Ion_trans_N PF08412.5 EMC82946.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal UPF0121 PF03661.8 EMC82947.1 - 2.1e-116 387.4 17.0 2.4e-116 387.2 11.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) BUD22 PF09073.5 EMC82948.1 - 6.4e-05 22.2 67.5 9.2e-05 21.6 46.8 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EMC82948.1 - 0.0043 15.0 75.8 0.0056 14.6 52.6 1.1 1 0 0 1 1 1 1 Nop14-like family Mitofilin PF09731.4 EMC82948.1 - 0.33 9.5 43.8 0.42 9.2 30.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nha1_C PF08619.5 EMC82948.1 - 0.95 8.6 60.7 1.4 8.0 42.1 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus PLRV_ORF5 PF01690.12 EMC82948.1 - 6.2 5.8 35.7 8.2 5.4 24.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Homeobox PF00046.24 EMC82949.1 - 4.7e-14 51.7 0.5 7.7e-14 51.0 0.3 1.3 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 EMC82950.1 - 2.8e-07 30.4 0.4 6.3e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 LIM domain Peptidase_C12 PF01088.16 EMC82951.1 - 1.8e-67 226.6 0.1 2e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PID PF00640.18 EMC82952.1 - 1.5e-62 209.7 0.1 6.1e-30 104.0 0.0 2.5 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.21 EMC82952.1 - 1.2e-06 28.2 2.0 2.8e-06 27.0 1.4 1.7 1 0 0 1 1 1 1 WW domain PTB PF08416.8 EMC82952.1 - 2.9e-06 27.2 0.0 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 2 Phosphotyrosine-binding domain Nol1_Nop2_Fmu PF01189.12 EMC82953.1 - 0.00082 18.8 0.1 0.0019 17.6 0.1 1.6 1 1 0 1 1 1 1 NOL1/NOP2/sun family Neur_chan_LBD PF02931.18 EMC82954.1 - 8.4e-67 224.4 2.1 1.1e-66 224.0 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC82954.1 - 1e-42 146.6 0.1 1.4e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GP41 PF00517.12 EMC82954.1 - 0.015 14.8 0.3 5.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Retroviral envelope protein L1R_F9L PF02442.12 EMC82954.1 - 0.085 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Hormone_recep PF00104.25 EMC82955.1 - 0.14 11.3 0.0 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Ras PF00071.17 EMC82956.1 - 6.9e-45 152.3 0.0 8.1e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC82956.1 - 3.1e-19 69.6 0.0 4.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC82956.1 - 8.9e-07 28.3 0.0 1.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC82956.1 - 0.0033 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EMC82956.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EMC82956.1 - 0.067 12.6 0.0 1.8 8.0 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EMC82956.1 - 0.087 12.0 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EMC82956.1 - 0.12 11.5 0.0 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EMC82956.1 - 0.14 12.1 0.0 0.48 10.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain HEAT PF02985.17 EMC82957.1 - 0.00047 20.0 3.8 43 4.5 0.0 7.2 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EMC82957.1 - 0.68 10.5 5.3 73 4.0 0.0 5.3 6 0 0 6 6 6 0 HEAT-like repeat UQ_con PF00179.21 EMC82958.1 - 9.2e-41 138.5 0.0 1.2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 EMC82958.1 - 7e-09 35.2 0.0 1.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 EMC82958.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC82958.1 - 0.0012 18.7 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UBA_3 PF09288.5 EMC82958.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF2615 PF11027.3 EMC82959.1 - 6.9e-43 144.7 0.0 7.6e-43 144.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) UDPG_MGDP_dh_N PF03721.9 EMC82960.1 - 2e-59 200.1 0.0 2.9e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EMC82960.1 - 4.2e-34 116.6 0.0 8.4e-34 115.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EMC82960.1 - 3.4e-27 94.6 0.0 4.3e-25 87.9 0.0 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.13 EMC82960.1 - 0.0015 18.1 0.0 0.098 12.3 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EMC82960.1 - 0.0074 16.1 0.1 3.2 7.5 0.0 3.8 2 2 2 4 4 4 1 lactate/malate dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMC82960.1 - 0.0079 15.9 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EMC82960.1 - 0.0084 16.3 0.0 8.5 6.6 0.0 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EMC82960.1 - 0.026 14.3 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EMC82960.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 EMC82960.1 - 0.069 13.5 0.0 3.6 8.0 0.0 3.3 4 1 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EMC82960.1 - 0.084 12.3 0.0 0.26 10.7 0.0 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Radical_SAM PF04055.16 EMC82961.1 - 7.9e-18 65.1 0.0 1.1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_L6 PF00347.18 EMC82962.1 - 6.3e-35 119.5 1.5 1.3e-16 60.8 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_1 PF00232.13 EMC82963.1 - 1.9e-211 702.1 17.1 6.5e-101 337.7 1.4 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 1 Y_phosphatase3C PF13348.1 EMC82963.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region Clathrin PF00637.15 EMC82964.1 - 8.6e-12 44.8 8.5 0.0022 17.6 0.1 5.1 3 1 1 5 5 5 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 EMC82964.1 - 1.3e-08 34.1 3.7 0.043 12.6 0.0 4.0 4 0 0 4 4 4 3 Coatomer WD associated region WD40 PF00400.27 EMC82964.1 - 4.2e-08 32.7 9.1 0.26 11.2 0.0 5.5 6 0 0 6 6 5 3 WD domain, G-beta repeat TPR_11 PF13414.1 EMC82964.1 - 3e-07 29.9 16.8 0.0056 16.3 0.9 5.6 5 1 1 6 6 6 3 TPR repeat Apc3 PF12895.2 EMC82964.1 - 1e-06 28.7 11.6 0.66 10.1 0.6 6.2 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EMC82964.1 - 0.00046 20.0 12.9 0.012 15.5 0.7 6.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC82964.1 - 0.00068 19.2 9.0 2.4 8.1 0.2 6.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC82964.1 - 0.0012 18.4 9.6 39 4.3 0.6 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat eIF2A PF08662.6 EMC82964.1 - 0.0022 17.7 0.0 0.0098 15.6 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPR_14 PF13428.1 EMC82964.1 - 0.0034 17.8 10.6 13 6.7 0.1 7.7 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC82964.1 - 0.0036 17.6 6.2 5.6 7.3 0.6 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat IKI3 PF04762.7 EMC82964.1 - 0.0039 15.0 0.3 0.31 8.7 0.0 3.0 3 0 0 3 3 3 1 IKI3 family DZR PF12773.2 EMC82964.1 - 0.0058 16.4 10.4 0.046 13.5 6.9 2.4 1 1 1 2 2 2 1 Double zinc ribbon SNAP PF14938.1 EMC82964.1 - 0.14 11.2 13.0 0.11 11.6 2.1 3.1 1 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 EMC82964.1 - 0.15 12.0 21.3 1.6 8.7 0.2 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC82964.1 - 2.2 8.0 19.9 8.7 6.1 0.6 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC82964.1 - 7.9 7.2 9.9 26 5.6 0.0 5.4 5 1 0 6 6 5 0 Tetratricopeptide repeat Kelch_1 PF01344.20 EMC82965.1 - 6.4e-82 268.9 10.0 3.4e-17 61.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC82965.1 - 1.6e-54 179.9 5.1 4.6e-11 42.3 0.0 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EMC82965.1 - 1.5e-34 116.4 6.8 1.7e-07 30.6 0.0 6.5 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 EMC82965.1 - 8.7e-34 115.4 1.1 2.6e-33 113.9 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 EMC82965.1 - 1.2e-33 114.6 9.8 2.4e-08 33.5 0.0 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 EMC82965.1 - 3.9e-30 104.0 0.2 6.7e-30 103.3 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 EMC82965.1 - 4.9e-29 99.8 12.2 1.5e-07 31.3 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC82965.1 - 7.6e-10 38.5 7.7 0.0098 15.8 0.0 6.0 7 0 0 7 7 7 2 Kelch motif Pet191_N PF10203.4 EMC82965.1 - 0.022 14.7 6.6 0.054 13.5 1.4 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PQQ_3 PF13570.1 EMC82965.1 - 0.23 11.8 8.9 13 6.2 0.0 4.6 5 0 0 5 5 5 0 PQQ-like domain HARP PF07443.8 EMC82965.1 - 1.4 8.3 12.6 22 4.5 0.0 5.5 6 0 0 6 6 6 0 HepA-related protein (HARP) TMEM156 PF15106.1 EMC82966.1 - 1.9e-73 246.4 8.0 2.3e-73 246.1 5.6 1.0 1 0 0 1 1 1 1 TMEM156 protein family DUF719 PF05334.8 EMC82967.1 - 4e-57 193.1 1.0 4e-57 193.1 0.7 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF719) DUF3402 PF11882.3 EMC82967.1 - 2.6 7.0 8.4 0.11 11.4 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) TIR PF01582.15 EMC82968.1 - 1.3e-34 118.6 0.2 2.6e-34 117.6 0.1 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.1 EMC82968.1 - 4.6e-15 55.1 9.8 1e-06 28.3 1.6 4.2 2 2 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC82968.1 - 2.3e-12 46.2 25.4 4.6e-06 26.1 0.6 6.9 5 2 3 8 8 8 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.1 EMC82968.1 - 2.8e-10 40.2 0.0 8e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.1 EMC82968.1 - 8.5e-08 31.5 12.3 0.28 11.3 0.0 7.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 EMC82968.1 - 1.4e-06 27.5 13.3 0.4 10.8 0.2 7.4 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC82968.1 - 0.00092 19.0 12.7 2.4 8.7 0.0 7.4 7 0 0 7 7 7 1 Leucine rich repeat LRRCT PF01463.19 EMC82968.1 - 0.002 18.2 0.1 0.0092 16.1 0.0 2.3 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 EMC82968.1 - 0.046 13.2 1.0 0.54 9.7 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeat TIR PF01582.15 EMC82969.1 - 1.6e-34 118.3 0.2 3.6e-34 117.2 0.1 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.1 EMC82969.1 - 1.2e-23 82.6 38.4 6e-08 32.3 5.6 6.9 3 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EMC82969.1 - 1.2e-22 79.0 42.1 4.3e-05 23.0 3.0 9.7 6 3 5 12 12 12 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC82969.1 - 5.2e-14 50.1 33.5 0.26 11.4 0.3 12.2 10 2 2 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 EMC82969.1 - 7.2e-14 50.2 28.7 0.35 11.0 0.0 11.2 8 2 2 10 10 10 5 Leucine Rich repeat TIR_2 PF13676.1 EMC82969.1 - 4.2e-10 39.6 0.0 1.1e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 TIR domain LRR_7 PF13504.1 EMC82969.1 - 1e-05 24.9 29.8 3 8.4 0.0 11.3 11 0 0 11 11 11 1 Leucine rich repeat LRRCT PF01463.19 EMC82969.1 - 0.002 18.2 0.5 0.012 15.8 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain zf-C2H2 PF00096.21 EMC82970.1 - 5.6e-14 51.5 24.9 2.6e-06 27.4 1.9 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC82970.1 - 3.4e-13 49.1 8.2 2e-09 37.2 0.8 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC82970.1 - 2.2e-09 36.9 20.2 0.0014 18.8 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMC82970.1 - 0.013 15.7 3.3 2.3 8.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC82970.1 - 0.11 12.6 3.6 3.5 7.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC82970.1 - 1.2 9.1 6.5 0.42 10.5 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RabGAP-TBC PF00566.13 EMC82971.1 - 2e-52 177.7 0.8 5.5e-52 176.3 0.6 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.3 EMC82971.1 - 8.2e-26 89.8 2.9 3.2e-25 87.8 2.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) PID PF00640.18 EMC82971.1 - 4.5e-09 36.4 0.9 1.3e-08 34.9 0.6 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) FANCI_S1-cap PF14674.1 EMC82971.1 - 0.63 10.1 4.1 9.2 6.4 0.1 2.9 2 0 0 2 2 2 0 FANCI solenoid 1 cap zf-C4H2 PF10146.4 EMC82971.1 - 2 8.4 21.7 0.67 9.9 3.3 3.4 2 1 0 3 3 3 0 Zinc finger-containing protein PGM_PMM_I PF02878.11 EMC82972.1 - 2.2e-36 124.3 0.0 4.2e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMC82972.1 - 7.1e-24 84.1 0.0 2.4e-23 82.4 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EMC82972.1 - 1e-11 44.8 0.3 6.4e-11 42.2 0.0 2.5 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EMC82972.1 - 3.4e-05 23.7 0.0 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RELT PF12606.3 EMC82973.1 - 4.4e-22 76.9 0.3 8.1e-22 76.1 0.2 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 TMEM171 PF15471.1 EMC82973.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF1811 PF08838.5 EMC82974.1 - 0.15 12.0 0.6 3.5 7.6 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1811) PQQ_2 PF13360.1 EMC82975.1 - 0.00077 18.9 0.1 0.076 12.4 0.0 2.9 2 0 0 2 2 2 2 PQQ-like domain AAA_28 PF13521.1 EMC82976.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EMC82976.1 - 0.013 15.1 0.2 0.075 12.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein STN1_2 PF09170.5 EMC82976.1 - 0.014 15.1 0.1 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 AAA PF00004.24 EMC82976.1 - 0.08 13.1 1.5 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC82976.1 - 0.15 12.8 1.3 1 10.1 0.1 2.7 2 1 1 3 3 3 0 AAA domain Death PF00531.17 EMC82977.1 - 0.00065 19.4 0.7 0.0013 18.5 0.5 1.5 1 0 0 1 1 1 1 Death domain PH PF00169.24 EMC82978.1 - 3.2e-41 139.7 18.9 9.4e-09 35.4 0.1 6.1 6 0 0 6 6 6 5 PH domain RhoGAP PF00620.22 EMC82978.1 - 6.9e-40 136.1 0.2 2.5e-39 134.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain ArfGap PF01412.13 EMC82978.1 - 2.9e-33 114.1 2.5 6.2e-33 113.0 0.1 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH_11 PF15413.1 EMC82978.1 - 6e-11 42.5 18.9 0.0005 20.2 0.2 7.3 5 3 0 5 5 5 3 Pleckstrin homology domain PH_6 PF15406.1 EMC82978.1 - 8.6e-11 41.8 0.2 3e-05 24.0 0.0 3.7 3 0 0 3 3 3 3 Pleckstrin homology domain SAM_2 PF07647.12 EMC82978.1 - 1.5e-09 37.5 0.0 6.7e-09 35.4 0.0 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC82978.1 - 1.4e-08 34.7 0.0 3.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EMC82978.1 - 7.6e-08 32.3 7.1 0.29 11.2 0.2 5.5 5 0 0 5 5 5 3 Pleckstrin homology domain PH_3 PF14593.1 EMC82978.1 - 1.1e-05 25.2 6.2 0.0096 15.7 0.1 3.9 4 0 0 4 4 4 2 PH domain RA PF00788.18 EMC82978.1 - 0.00028 21.2 0.0 0.0015 18.9 0.0 2.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Mcp5_PH PF12814.2 EMC82978.1 - 0.00048 20.0 3.1 0.33 10.8 0.0 4.1 4 0 0 4 4 4 1 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 EMC82978.1 - 0.053 13.0 5.5 2.6 7.5 0.0 4.0 4 0 0 4 4 4 0 Pleckstrin homology domain SAM_2 PF07647.12 EMC82981.1 - 3.8e-12 45.8 0.1 1e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC82981.1 - 1.9e-06 27.9 0.1 5.9e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4446 PF14584.1 EMC82981.1 - 0.33 10.7 6.2 0.05 13.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.14 EMC82981.1 - 8.7 4.0 12.0 16 3.1 8.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RabGAP-TBC PF00566.13 EMC82982.1 - 2.4e-14 53.3 8.0 1.7e-11 43.9 2.2 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain 7tm_1 PF00001.16 EMC82983.1 - 1.5e-67 227.4 17.7 2.3e-67 226.8 12.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.5 EMC82983.1 - 4.7e-24 84.0 0.1 1e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Cholecystokinin A receptor, N-terminal 7TM_GPCR_Srsx PF10320.4 EMC82983.1 - 6.1e-08 32.1 23.8 4.9e-07 29.1 16.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC82983.1 - 5.3e-05 22.4 17.7 5.3e-05 22.4 12.3 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Brr6_like_C_C PF10104.4 EMC82983.1 - 1.1 8.8 9.7 0.063 12.7 1.3 2.9 2 2 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain BTD PF09270.5 EMC82984.1 - 2.6e-65 218.9 0.0 4.2e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EMC82984.1 - 3.5e-56 189.5 0.8 6.3e-56 188.7 0.5 1.4 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 EMC82984.1 - 2.4e-08 33.8 0.9 1.4e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ig_2 PF13895.1 EMC82984.1 - 0.025 14.6 0.1 0.47 10.6 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin domain Sel1 PF08238.7 EMC82985.1 - 5.4e-17 61.8 40.1 0.00019 21.9 0.1 9.7 10 0 0 10 10 10 5 Sel1 repeat TPR_16 PF13432.1 EMC82985.1 - 0.007 17.0 3.9 0.33 11.6 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Laminin_G_2 PF02210.19 EMC82985.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Na_Pi_cotrans PF02690.10 EMC82986.1 - 3.4e-57 192.1 26.9 2.2e-30 105.2 6.4 2.7 2 1 0 2 2 2 2 Na+/Pi-cotransporter DUF2244 PF10003.4 EMC82986.1 - 0.28 10.5 5.9 1.3 8.4 4.1 2.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) zf-CCHC PF00098.18 EMC82987.1 - 0.0011 18.7 2.4 0.0011 18.7 1.7 3.1 4 0 0 4 4 4 1 Zinc knuckle zf-DHHC PF01529.15 EMC82987.1 - 0.002 17.5 5.2 0.002 17.5 3.6 2.4 1 1 1 2 2 2 2 DHHC palmitoyltransferase PI3_PI4_kinase PF00454.22 EMC82988.1 - 2.8e-59 200.4 0.0 3.7e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SLA_LP_auto_ag PF05889.8 EMC82989.1 - 6.1e-179 594.4 0.0 7.1e-179 594.2 0.0 1.0 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 EMC82989.1 - 3.8e-05 22.9 0.0 5.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 EMC82989.1 - 0.0038 15.7 0.1 0.099 11.0 0.1 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain EPTP PF03736.12 EMC82990.1 - 5.4e-94 307.7 21.5 6.3e-15 54.6 0.1 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 EMC82990.1 - 3.2e-19 68.4 5.6 3.2e-14 52.4 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EMC82990.1 - 1.6e-10 40.3 0.2 4.1e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC82990.1 - 2.8e-09 35.7 2.4 0.16 12.1 0.1 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_5 PF13306.1 EMC82990.1 - 3.6e-06 26.6 0.2 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC82990.1 - 0.00032 20.4 0.5 1.2 9.6 0.1 3.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.1 EMC82990.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.1 EMC82990.1 - 0.12 12.5 2.6 29 5.1 0.2 3.8 3 0 0 3 3 3 0 Leucine Rich repeat DUF2353 PF09789.4 EMC82991.1 - 1.2e-89 300.7 23.2 1.6e-89 300.3 16.1 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 EMC82991.1 - 0.0023 17.5 16.1 0.0023 17.5 11.2 3.8 2 2 1 3 3 2 1 IncA protein THP2 PF09432.5 EMC82991.1 - 0.0038 17.0 4.7 0.01 15.6 3.2 1.7 1 0 0 1 1 1 1 Tho complex subunit THP2 KLRAQ PF10205.4 EMC82991.1 - 0.039 13.9 18.8 0.35 10.9 5.8 3.9 2 1 2 4 4 4 0 Predicted coiled-coil domain-containing protein DivIVA PF05103.8 EMC82991.1 - 0.049 13.6 20.2 0.13 12.2 4.4 3.2 2 1 1 3 3 3 0 DivIVA protein TSC22 PF01166.13 EMC82991.1 - 0.055 13.4 21.7 0.18 11.7 0.1 4.9 5 0 0 5 5 5 0 TSC-22/dip/bun family DUF3426 PF11906.3 EMC82991.1 - 0.1 12.2 0.3 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) DUF869 PF05911.6 EMC82991.1 - 0.21 9.7 24.0 0.034 12.3 4.2 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) Mnd1 PF03962.10 EMC82991.1 - 0.23 11.1 23.7 0.22 11.1 4.2 3.1 2 1 0 3 3 3 0 Mnd1 family OEP PF02321.13 EMC82991.1 - 0.27 10.8 11.2 0.65 9.5 7.8 1.7 1 0 0 1 1 1 0 Outer membrane efflux protein DUF342 PF03961.8 EMC82991.1 - 0.28 9.5 17.3 0.63 8.3 3.6 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Prefoldin PF02996.12 EMC82991.1 - 0.29 10.7 16.2 0.48 10.0 0.7 4.2 4 0 0 4 4 4 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 EMC82991.1 - 0.44 10.5 21.4 0.8 9.7 3.7 4.1 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Ufd2P_core PF10408.4 EMC82991.1 - 0.57 8.3 8.4 0.18 9.9 3.6 1.7 1 1 1 2 2 2 0 Ubiquitin elongating factor core GAS PF13851.1 EMC82991.1 - 0.58 9.3 31.8 3.7 6.6 9.1 3.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 EMC82991.1 - 0.66 8.9 17.9 0.023 13.7 5.7 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.7 EMC82991.1 - 0.71 9.6 18.9 0.77 9.5 0.4 4.1 3 1 1 4 4 4 0 Laminin Domain II COG2 PF06148.6 EMC82991.1 - 0.75 9.6 14.8 0.44 10.4 1.0 3.3 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 THOC7 PF05615.8 EMC82991.1 - 0.9 9.7 16.2 0.26 11.5 1.6 3.8 3 0 0 3 3 3 0 Tho complex subunit 7 FliD_N PF02465.13 EMC82991.1 - 1.1 9.6 10.2 14 6.1 0.7 3.5 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4140 PF13600.1 EMC82991.1 - 1.5 9.3 27.0 3.9 7.9 2.5 5.2 5 1 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.1 EMC82991.1 - 1.7 8.8 20.9 2.2 8.4 5.2 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Lebercilin PF15619.1 EMC82991.1 - 2.6 7.4 34.2 1.2 8.4 18.9 3.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Myb_DNA-bind_5 PF13873.1 EMC82991.1 - 3.2 7.7 8.2 4.6 7.1 0.2 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DASH_Dam1 PF08653.5 EMC82991.1 - 4 7.2 5.0 11 5.8 0.0 3.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 SlyX PF04102.7 EMC82991.1 - 4.1 7.8 29.2 4.3 7.7 0.9 5.0 4 1 1 5 5 4 0 SlyX LXG PF04740.7 EMC82991.1 - 7.1 6.3 13.8 0.81 9.4 1.0 3.6 4 0 0 4 4 4 0 LXG domain of WXG superfamily Cep57_MT_bd PF06657.8 EMC82991.1 - 8.7 6.3 20.9 0.81 9.6 0.3 4.8 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Phlebovirus_NSM PF07246.6 EMC82991.1 - 9.5 5.2 13.1 6.2 5.8 1.0 2.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Sod_Cu PF00080.15 EMC82992.1 - 2.1e-32 112.1 0.0 2.5e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) OB_NTP_bind PF07717.11 EMC82993.1 - 6.7e-31 106.4 0.1 1.2e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC82993.1 - 1e-26 92.8 0.3 2.6e-26 91.5 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC82993.1 - 5.1e-12 45.4 0.0 2.2e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC82993.1 - 9e-07 28.5 0.2 2.9e-06 26.8 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC82993.1 - 9e-05 22.6 0.0 0.00041 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EMC82993.1 - 0.0019 18.0 0.0 0.99 9.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EMC82993.1 - 0.0036 16.7 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EMC82993.1 - 0.0038 16.7 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EMC82993.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EMC82993.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 EMC82993.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.1 EMC82993.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMC82993.1 - 0.068 12.0 0.0 0.17 10.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein HTH_IclR PF09339.5 EMC82993.1 - 0.08 12.5 0.1 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain RRM_1 PF00076.17 EMC82994.1 - 3.5e-07 29.7 0.0 7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC82994.1 - 4.1e-05 23.4 0.0 8.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC82994.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-ODYAM1 PF15642.1 EMC82994.1 - 0.24 10.0 1.3 0.43 9.2 0.9 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus PCAF_N PF06466.6 EMC82995.1 - 0.0029 16.9 0.8 0.0053 16.1 0.5 1.4 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain 7tm_2 PF00002.19 EMC82996.1 - 4.8e-14 52.0 5.1 8.4e-14 51.2 3.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) LRR_8 PF13855.1 EMC82996.1 - 2e-13 49.8 6.5 5.4e-12 45.2 3.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat GPS PF01825.16 EMC82996.1 - 5.3e-09 36.0 4.0 1e-08 35.1 0.0 3.2 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain I-set PF07679.11 EMC82996.1 - 1.8e-06 27.7 0.0 4.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.2 EMC82996.1 - 1.5e-05 24.5 7.1 0.00036 20.0 1.1 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) HRM PF02793.17 EMC82996.1 - 0.00025 20.9 0.8 0.00068 19.5 0.5 1.8 1 0 0 1 1 1 1 Hormone receptor domain LRR_1 PF00560.28 EMC82996.1 - 0.0018 18.0 8.0 0.58 10.3 0.2 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat PalH PF08733.5 EMC82996.1 - 0.19 10.5 9.0 0.37 9.5 6.3 1.3 1 0 0 1 1 1 0 PalH/RIM21 LRR_6 PF13516.1 EMC82996.1 - 1.6 9.0 5.0 5.8 7.3 0.3 3.1 2 0 0 2 2 2 0 Leucine Rich repeat EF-hand_7 PF13499.1 EMC82997.1 - 7.3e-23 80.4 1.4 8e-16 57.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC82997.1 - 4.3e-21 72.5 10.7 7.8e-08 31.0 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC82997.1 - 1.4e-18 65.0 5.4 4.9e-06 25.9 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EMC82997.1 - 3.2e-17 61.0 2.3 2.6e-05 23.3 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EMC82997.1 - 8.3e-14 50.9 13.7 7.6e-06 25.4 1.1 5.0 3 1 2 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC82997.1 - 3.9e-08 33.3 2.2 2e-05 24.5 0.1 3.4 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC82997.1 - 0.00019 21.1 2.2 0.01 15.5 0.1 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC82997.1 - 0.015 15.1 0.5 2.9 7.8 0.0 3.1 1 1 1 2 2 2 0 EF-hand domain S10_plectin PF03501.10 EMC82997.1 - 0.016 15.0 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 EMC82997.1 - 0.057 13.4 0.1 2.2 8.3 0.0 2.7 2 1 0 2 2 2 0 EF hand DUF3192 PF11399.3 EMC82997.1 - 0.13 12.2 0.7 2.9 7.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3192) ParcG PF10274.4 EMC82998.1 - 4.9e-46 156.9 0.0 6.4e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein HEAT_EZ PF13513.1 EMC82998.1 - 0.0019 18.6 0.5 0.014 15.8 0.1 2.2 1 1 1 2 2 2 1 HEAT-like repeat LRR_8 PF13855.1 EMC82999.1 - 1.9e-81 267.7 80.6 2.6e-13 49.5 0.0 10.2 4 4 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 EMC82999.1 - 7.6e-49 162.6 45.7 3.6e-07 29.6 0.4 10.8 9 1 1 10 10 10 10 Leucine Rich repeats (2 copies) EGF PF00008.22 EMC82999.1 - 1.6e-37 127.0 156.4 1e-08 34.9 5.4 11.7 12 0 0 12 12 10 8 EGF-like domain Laminin_G_1 PF00054.18 EMC82999.1 - 1.3e-26 93.1 0.0 2.2e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 EMC82999.1 - 1.7e-24 86.2 0.0 3.9e-24 85.1 0.0 1.6 2 0 0 2 2 2 1 Laminin G domain LRR_1 PF00560.28 EMC82999.1 - 1.7e-22 75.9 50.9 0.17 12.0 0.0 19.0 20 0 0 20 20 20 8 Leucine Rich Repeat LRRNT PF01462.13 EMC82999.1 - 5.6e-17 60.7 24.9 3.8e-08 32.6 2.2 8.7 9 0 0 9 9 8 3 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 EMC82999.1 - 1.5e-14 53.9 17.5 0.00069 19.2 0.2 5.4 4 1 1 5 5 5 5 Leucine-rich repeat LRRCT PF01463.19 EMC82999.1 - 2e-13 49.2 5.7 0.016 15.4 0.0 6.7 6 0 0 6 6 4 4 Leucine rich repeat C-terminal domain hEGF PF12661.2 EMC82999.1 - 2.9e-10 39.5 95.2 0.041 13.9 1.6 11.4 10 0 0 10 10 9 8 Human growth factor-like EGF FXa_inhibition PF14670.1 EMC82999.1 - 0.0045 17.0 4.0 0.0045 17.0 2.8 11.7 8 4 3 11 11 9 4 Coagulation Factor Xa inhibitory site LRR_6 PF13516.1 EMC82999.1 - 0.15 12.2 0.0 0.21 11.7 0.0 14.9 14 3 5 19 19 16 0 Leucine Rich repeat LRR_7 PF13504.1 EMC82999.1 - 4.9 7.7 56.5 22 5.8 0.1 15.7 17 0 0 17 17 15 0 Leucine rich repeat HTH_psq PF05225.11 EMC83000.1 - 5.1e-22 77.1 0.0 7.3e-15 54.2 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain DUF4553 PF15090.1 EMC83001.1 - 4.9e-181 602.7 28.1 4.9e-181 602.7 19.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) MRP-L51 PF10244.4 EMC83001.1 - 0.19 11.7 5.4 5.3 7.1 0.2 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit Cnd3 PF12719.2 EMC83002.1 - 2e-73 247.0 6.8 8.2e-73 244.9 2.5 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EMC83002.1 - 1.8e-12 47.3 6.8 8.7e-05 22.7 0.0 6.2 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 EMC83002.1 - 1e-06 28.3 8.7 2.9 8.2 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EMC83002.1 - 1.8e-06 28.2 7.9 0.6 10.6 0.0 6.2 6 0 0 6 6 6 3 HEAT-like repeat UVR PF02151.14 EMC83002.1 - 0.00026 20.3 0.2 0.00026 20.3 0.1 3.1 3 0 0 3 3 3 1 UvrB/uvrC motif WEMBL PF05701.6 EMC83003.1 - 9.1e-05 21.1 18.5 9.1e-05 21.1 12.9 3.0 1 1 2 3 3 3 1 Weak chloroplast movement under blue light DivIC PF04977.10 EMC83003.1 - 0.021 14.3 0.8 0.021 14.3 0.5 7.1 1 1 7 9 9 9 0 Septum formation initiator Med28 PF11594.3 EMC83004.1 - 3.5e-42 142.9 1.0 4.1e-42 142.7 0.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 28 HTH_34 PF13601.1 EMC83004.1 - 0.0023 17.9 0.1 0.0049 16.8 0.0 1.5 1 1 0 1 1 1 1 Winged helix DNA-binding domain Filament PF00038.16 EMC83004.1 - 0.012 15.0 1.3 0.013 14.9 0.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein Fzo_mitofusin PF04799.8 EMC83004.1 - 0.17 11.2 2.4 0.2 11.0 1.7 1.1 1 0 0 1 1 1 0 fzo-like conserved region Fib_alpha PF08702.5 EMC83004.1 - 0.18 11.9 3.0 0.24 11.5 2.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_M17 PF00883.16 EMC83005.1 - 6e-121 403.0 0.0 7.4e-121 402.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EMC83005.1 - 6.6e-24 84.0 0.6 1.4e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Claudin_2 PF13903.1 EMC83006.1 - 8.7e-09 35.2 4.7 1.3e-08 34.7 3.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.6 EMC83006.1 - 0.0013 18.5 10.9 0.007 16.0 7.5 2.1 1 1 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 EMC83006.1 - 0.0016 18.1 2.5 0.0023 17.6 1.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF3112 PF11309.3 EMC83006.1 - 2.3 8.0 6.4 3.8 7.2 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) LIM_bind PF01803.11 EMC83007.1 - 9.2e-69 231.1 2.6 9.2e-69 231.1 1.8 2.7 2 1 0 2 2 2 1 LIM-domain binding protein Vpu PF00558.14 EMC83007.1 - 0.43 10.1 1.6 5.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Vpu protein DUF747 PF05346.6 EMC83008.1 - 2.6e-102 342.3 17.5 3.4e-102 341.8 12.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DASH_Dad4 PF08650.5 EMC83008.1 - 0.12 12.3 3.4 0.95 9.4 1.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 FGF-BP1 PF06473.7 EMC83009.1 - 8.4e-60 202.2 0.5 1e-59 201.9 0.4 1.1 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) FGF-BP1 PF06473.7 EMC83010.1 - 3.7e-50 170.6 17.9 3.3e-49 167.5 12.4 1.9 1 1 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Protocadherin PF08374.6 EMC83010.1 - 0.093 12.3 1.9 0.11 12.0 0.7 1.4 1 1 0 1 1 1 0 Protocadherin Rib_hydrolayse PF02267.12 EMC83011.1 - 2.2e-89 298.9 0.0 2.5e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase F-box-like PF12937.2 EMC83012.1 - 2.9e-16 58.9 0.1 1.1e-15 57.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EMC83012.1 - 4.5e-12 45.2 2.5 5.4e-06 25.9 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC83012.1 - 6.3e-12 44.2 5.4 0.042 13.9 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich repeat F-box PF00646.28 EMC83012.1 - 7.5e-11 41.3 0.5 6.2e-10 38.4 0.0 2.8 3 0 0 3 3 3 1 F-box domain Hemerythrin PF01814.18 EMC83012.1 - 1.2e-08 35.1 0.2 2.5e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain LRR_1 PF00560.28 EMC83012.1 - 5.9e-08 31.6 7.9 0.099 12.7 0.0 5.9 6 0 0 6 6 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC83012.1 - 9.1e-07 28.0 2.5 0.73 10.2 0.0 5.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_8 PF13855.1 EMC83012.1 - 1.2e-06 28.1 2.4 0.0012 18.5 0.1 3.4 2 1 0 2 2 2 2 Leucine rich repeat PRANC PF09372.5 EMC83012.1 - 0.077 12.9 0.0 0.077 12.9 0.0 2.5 3 1 0 3 3 3 0 PRANC domain Racemase_4 PF13615.1 EMC83012.1 - 0.082 13.1 0.4 1.5 9.1 0.1 2.6 2 0 0 2 2 2 0 Putative alanine racemase NAAA-beta PF15508.1 EMC83012.1 - 0.13 12.6 0.4 0.46 10.8 0.3 2.0 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Orthopox_A5L PF06193.6 EMC83012.1 - 0.24 11.3 5.7 0.048 13.6 1.0 2.0 2 1 0 2 2 2 0 Orthopoxvirus A5L protein-like CC2D2AN-C2 PF15625.1 EMC83013.1 - 3.2e-41 140.6 0.0 5.9e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.25 EMC83013.1 - 0.00089 19.0 0.3 0.019 14.8 0.0 2.5 2 0 0 2 2 2 1 C2 domain DUF3987 PF13148.1 EMC83013.1 - 0.004 15.7 14.1 0.012 14.1 9.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) DUF106 PF01956.11 EMC83013.1 - 2 7.8 4.2 6.4 6.2 2.9 1.9 1 0 0 1 1 1 0 Integral membrane protein DUF106 C1q PF00386.16 EMC83014.1 - 1.2e-38 131.9 0.0 1.6e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC83014.1 - 3.7e-16 58.4 57.7 4.9e-09 35.5 17.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) RRM_1 PF00076.17 EMC83015.1 - 9.2e-13 47.6 0.0 1.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC83015.1 - 2.9e-07 30.3 0.0 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.16 EMC83015.1 - 0.052 13.4 0.0 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-U1 PF06220.7 EMC83015.1 - 0.058 12.9 0.3 0.16 11.5 0.2 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-B_box PF00643.19 EMC83015.1 - 0.069 13.0 6.2 0.17 11.8 4.3 1.6 1 0 0 1 1 1 0 B-box zinc finger DUF2890 PF11081.3 EMC83017.1 - 0.63 10.0 19.2 0.5 10.3 12.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) DUF605 PF04652.11 EMC83017.1 - 7.9 5.7 19.2 9.4 5.5 13.3 1.0 1 0 0 1 1 1 0 Vta1 like DNA_pol_phi PF04931.8 EMC83017.1 - 8.2 4.0 9.0 13 3.4 6.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Homeobox PF00046.24 EMC83018.1 - 1.1e-21 76.2 1.9 1.3e-21 75.9 1.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC83018.1 - 0.041 12.9 0.1 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC83018.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Homeobox KN domain Ras PF00071.17 EMC83019.1 - 4.8e-40 136.5 0.1 6.5e-40 136.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83019.1 - 2e-15 57.3 0.0 3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83019.1 - 1.2e-11 44.1 0.1 1.5e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC83019.1 - 0.00015 20.9 0.1 0.00021 20.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Flt3_lig PF02947.9 EMC83019.1 - 0.046 13.6 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 flt3 ligand PduV-EutP PF10662.4 EMC83019.1 - 0.075 12.5 0.1 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sulfotransfer_1 PF00685.22 EMC83020.1 - 4.8e-38 130.9 0.4 6.5e-38 130.5 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 EMC83020.1 - 0.0023 17.6 0.2 0.0053 16.4 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.1 EMC83020.1 - 0.0025 18.7 0.5 0.009 16.9 0.3 2.1 1 1 0 1 1 1 1 Sulfotransferase family Proho_convert PF12177.3 EMC83020.1 - 0.023 14.2 0.1 0.069 12.7 0.0 1.8 1 0 0 1 1 1 0 Prohormone convertase enzyme zf-H2C2_2 PF13465.1 EMC83021.1 - 2e-05 24.6 0.6 2e-05 24.6 0.4 6.0 6 0 0 6 6 6 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMC83021.1 - 5.7e-05 23.1 23.2 0.011 15.8 1.0 4.9 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EMC83021.1 - 0.02 15.2 29.7 0.83 10.1 0.1 5.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type Sugar_tr PF00083.19 EMC83022.1 - 1.4e-100 337.0 30.4 1.8e-100 336.6 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC83022.1 - 1.3e-23 83.2 40.8 3.5e-17 62.1 4.5 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Otopetrin PF03189.8 EMC83023.1 - 9.7e-40 136.8 15.8 2e-18 66.6 3.0 3.3 2 1 0 3 3 3 3 Otopetrin DUF2975 PF11188.3 EMC83023.1 - 1.1 8.9 15.2 0.22 11.2 1.5 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) zf-LYAR PF08790.6 EMC83025.1 - 5.1e-14 51.6 1.4 5.1e-14 51.6 1.0 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger IBR PF01485.16 EMC83025.1 - 0.65 9.9 12.0 1.8 8.4 8.3 1.8 1 0 0 1 1 1 0 IBR domain C1_4 PF07975.7 EMC83025.1 - 0.79 9.7 10.0 2.6 8.1 6.9 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain Mut7-C PF01927.11 EMC83025.1 - 8.7 6.3 10.7 9.7 6.1 5.7 2.4 2 1 1 3 3 3 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.1 EMC83026.1 - 2.6e-45 150.5 44.2 2e-07 30.9 1.1 8.5 7 1 1 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 EMC83026.1 - 7e-32 107.8 50.1 3.3e-06 27.1 0.8 8.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type BTB PF00651.26 EMC83026.1 - 6.6e-26 90.4 0.8 1.4e-25 89.4 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.1 EMC83026.1 - 2.8e-20 71.4 39.8 0.00023 20.9 0.3 7.8 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMC83026.1 - 3.3e-19 67.7 43.2 0.00016 21.7 0.7 7.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83026.1 - 3.3e-18 65.2 28.0 0.00058 19.9 0.5 8.2 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC83026.1 - 2.8e-10 40.0 34.7 0.0046 17.1 0.5 8.2 8 0 0 8 8 8 4 Zinc-finger of C2H2 type GAGA PF09237.6 EMC83026.1 - 0.0031 17.0 12.8 0.13 11.9 0.1 4.9 2 2 3 5 5 5 2 GAGA factor zf-BED PF02892.10 EMC83026.1 - 0.017 14.8 1.5 0.017 14.8 1.0 6.7 1 1 6 7 7 7 0 BED zinc finger Elf1 PF05129.8 EMC83026.1 - 0.1 12.2 21.6 0.074 12.7 1.6 4.4 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 EMC83026.1 - 0.45 10.2 29.3 0.68 9.6 0.3 6.3 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EMC83026.1 - 2.4 8.1 31.6 5.8 6.9 4.7 6.0 4 1 0 5 5 5 0 Zinc ribbon domain Calcyon PF06387.6 EMC83027.1 - 4.3e-96 319.6 0.2 4.8e-96 319.5 0.1 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) DUF2448 PF10476.4 EMC83027.1 - 0.013 15.0 0.1 0.029 13.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) MgsA_C PF12002.3 EMC83027.1 - 0.022 14.4 0.2 0.039 13.6 0.2 1.3 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal CPW_WPC PF09717.5 EMC83027.1 - 0.092 13.3 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Syntaxin-18_N PF10496.4 EMC83028.1 - 1.1e-09 37.9 0.3 3.4e-09 36.4 0.2 1.9 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus TipAS PF07739.8 EMC83028.1 - 0.023 15.0 3.0 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain SNARE PF05739.14 EMC83028.1 - 0.026 14.2 3.6 0.059 13.0 2.5 1.6 1 0 0 1 1 1 0 SNARE domain Mod_r PF07200.8 EMC83028.1 - 2 8.3 6.9 0.42 10.5 1.4 2.1 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Homeobox PF00046.24 EMC83030.1 - 4.2e-22 77.5 4.6 6.5e-22 76.9 3.2 1.3 1 0 0 1 1 1 1 Homeobox domain CYTL1 PF15153.1 EMC83031.1 - 5.2e-55 184.7 2.8 6.3e-55 184.4 1.9 1.0 1 0 0 1 1 1 1 Cytokine-like protein 1 Pkinase PF00069.20 EMC83032.1 - 2.6e-61 207.0 0.0 3.4e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83032.1 - 6.6e-36 123.7 0.0 9.4e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC83032.1 - 7.1e-11 41.5 0.0 9.6e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC83032.1 - 0.0024 17.6 0.5 0.0042 16.8 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF948 PF06103.6 EMC83033.1 - 0.49 10.2 13.7 0.058 13.2 0.9 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Polyoma_coat2 PF00761.15 EMC83033.1 - 0.58 9.5 3.9 0.94 8.9 1.2 2.4 2 0 0 2 2 2 0 Polyomavirus coat protein ADIP PF11559.3 EMC83035.1 - 0.0033 17.3 13.5 0.0033 17.3 9.3 9.0 5 4 5 10 10 10 6 Afadin- and alpha -actinin-Binding WD40 PF00400.27 EMC83036.1 - 2.5e-11 43.0 5.9 0.68 9.9 0.1 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat TACC PF05010.9 EMC83037.1 - 3.6e-80 268.5 40.9 3.6e-80 268.5 28.3 2.0 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) DUF1342 PF07072.6 EMC83037.1 - 2.6 7.6 15.6 0.07 12.7 2.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1342) Tmpp129 PF10272.4 EMC83038.1 - 4.4e-158 525.6 1.8 5e-158 525.4 1.3 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor C1_4 PF07975.7 EMC83038.1 - 0.0092 15.9 0.9 0.0092 15.9 0.6 2.6 1 1 1 2 2 2 1 TFIIH C1-like domain Dexa_ind PF15198.1 EMC83038.1 - 0.15 11.9 0.7 3.6 7.5 0.0 2.4 1 1 1 2 2 2 0 Dexamethasone-induced zf-RING_2 PF13639.1 EMC83038.1 - 5.3 6.9 15.8 16 5.3 11.0 1.9 1 1 0 1 1 1 0 Ring finger domain TLV_coat PF00429.14 EMC83039.1 - 1.1e-11 43.9 2.0 1.3e-11 43.7 1.4 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) SLBP_RNA_bind PF15247.1 EMC83040.1 - 6.1e-34 115.6 4.4 1.9e-33 114.0 3.1 1.8 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain FAM53 PF15242.1 EMC83041.1 - 8.2e-110 367.2 22.7 2.3e-108 362.4 15.8 2.1 1 1 0 1 1 1 1 Family of FAM53 DUF2043 PF09740.4 EMC83043.1 - 1.4e-46 157.1 1.4 3e-46 156.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) CLTH PF10607.4 EMC83044.1 - 2.6e-32 111.5 0.5 3.7e-32 111.0 0.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EMC83044.1 - 0.00067 19.3 0.6 0.024 14.3 0.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger 2-Hacid_dh_C PF02826.14 EMC83045.1 - 4.1e-57 192.1 0.0 5.9e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC83045.1 - 1.7e-28 98.7 0.0 2.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC83045.1 - 1.3e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Cellsynth_D PF03500.8 EMC83045.1 - 0.02 14.5 0.0 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 Cellulose synthase subunit D XdhC_C PF13478.1 EMC83045.1 - 0.026 14.8 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Spond_N PF06468.8 EMC83046.1 - 5.2e-88 293.8 0.3 6.4e-88 293.5 0.2 1.1 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.14 EMC83046.1 - 0.0018 18.3 3.6 0.0034 17.4 2.5 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain Neogenin_C PF06583.7 EMC83046.1 - 0.064 12.8 0.2 0.59 9.6 0.0 2.1 2 0 0 2 2 2 0 Neogenin C-terminus EMP24_GP25L PF01105.19 EMC83047.1 - 3.5e-44 150.7 0.2 3.9e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF342 PF03961.8 EMC83047.1 - 0.045 12.1 0.1 0.057 11.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3338 PF11819.3 EMC83048.1 - 0.034 13.5 0.5 0.05 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) RNA_lig_T4_1 PF09511.5 EMC83048.1 - 0.035 13.5 0.1 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA ligase Tautomerase_3 PF14832.1 EMC83048.1 - 0.037 14.0 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme I-set PF07679.11 EMC83049.1 - 5.4e-47 157.5 0.0 2.8e-17 62.3 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83049.1 - 1.1e-29 102.3 0.0 1.2e-11 44.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC83049.1 - 3.5e-22 78.2 0.0 2.9e-09 36.9 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC83049.1 - 2.7e-19 69.1 0.7 1.1e-06 28.5 0.0 4.6 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC83049.1 - 3.2e-18 65.9 0.0 1e-05 25.9 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain Herpes_gE PF02480.11 EMC83049.1 - 3e-06 25.7 0.0 0.21 9.7 0.0 3.2 1 1 1 3 3 3 3 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 EMC83049.1 - 4.7e-06 26.4 0.2 0.0027 17.5 0.0 3.1 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 EMC83049.1 - 0.00061 19.6 0.0 3.3 7.6 0.0 3.2 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 EMC83049.1 - 0.027 13.5 0.0 16 4.5 0.0 3.0 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I V-set_CD47 PF08204.6 EMC83049.1 - 0.14 11.9 0.2 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain HLH PF00010.21 EMC83050.1 - 7.3e-06 25.5 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_29 PF00777.13 EMC83051.1 - 2.7e-72 243.0 0.0 4.2e-72 242.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RNA_pol_Rpb1_5 PF04998.12 EMC83052.1 - 2e-105 351.9 0.0 4.7e-105 350.8 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 EMC83052.1 - 5.9e-25 87.1 0.4 2.1e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 HMG_box PF00505.14 EMC83052.1 - 0.039 14.2 1.5 0.086 13.1 0.2 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box RNA_pol_Rpb1_1 PF04997.7 EMC83053.1 - 4.4e-12 45.9 1.2 5e-12 45.7 0.8 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 zf-RING_4 PF14570.1 EMC83053.1 - 0.028 13.9 3.5 0.028 13.9 2.4 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Mitofilin PF09731.4 EMC83054.1 - 3.2e-176 587.4 38.9 4.3e-176 587.0 26.9 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein MRP-S23 PF10484.4 EMC83054.1 - 0.012 15.4 0.0 0.087 12.7 0.0 2.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 CAV_VP3 PF04771.7 EMC83054.1 - 0.018 14.9 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Phospholip_B PF04916.8 EMC83054.1 - 3.7 5.5 9.5 1 7.4 3.7 2.0 1 1 1 2 2 2 0 Phospholipase B Ribosomal_L35p PF01632.14 EMC83055.1 - 6.4e-23 80.4 9.3 9e-23 79.9 6.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 PMSR PF01625.16 EMC83055.1 - 0.1 12.5 0.1 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase DUF3437 PF11919.3 EMC83055.1 - 0.1 12.3 0.1 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3437) IL33 PF15095.1 EMC83055.1 - 0.35 10.2 2.8 0.4 10.0 1.9 1.1 1 0 0 1 1 1 0 Interleukin 33 TB2_DP1_HVA22 PF03134.14 EMC83056.1 - 1.8e-31 107.7 11.0 2.6e-31 107.2 7.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.4 EMC83056.1 - 0.024 14.7 0.2 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Halogen_Hydrol PF10112.4 EMC83056.1 - 0.062 12.7 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Snf7 PF03357.16 EMC83057.1 - 2.5e-40 137.6 15.7 2.5e-40 137.6 10.9 1.3 2 0 0 2 2 2 1 Snf7 zf-ZPR1 PF03367.8 EMC83057.1 - 0.0063 15.6 0.9 0.0063 15.6 0.6 1.6 2 0 0 2 2 2 1 ZPR1 zinc-finger domain DUF3915 PF13054.1 EMC83057.1 - 0.061 13.2 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Cauli_AT PF03233.8 EMC83057.1 - 0.44 10.2 4.0 0.2 11.3 0.2 2.0 1 1 1 2 2 2 0 Aphid transmission protein PSD4 PF07631.6 EMC83057.1 - 0.44 10.9 2.3 1.5 9.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) DUF3818 PF12825.2 EMC83057.1 - 0.53 8.8 5.2 0.71 8.4 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) NPV_P10 PF05531.7 EMC83057.1 - 2.3 8.5 5.2 9.5 6.5 0.3 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CLTH PF10607.4 EMC83058.1 - 7.8e-31 106.7 0.0 2.3e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EMC83058.1 - 1.8e-18 65.9 1.9 4.2e-18 64.7 0.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMC83058.1 - 9.5e-05 22.1 0.2 0.00025 20.8 0.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 EMC83058.1 - 0.0082 15.6 1.2 0.019 14.5 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SnoaL_4 PF13577.1 EMC83058.1 - 0.026 14.4 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain zf-C3HC4_2 PF13923.1 EMC83058.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC83058.1 - 0.76 9.5 4.2 0.28 10.9 0.8 1.9 2 0 0 2 2 2 0 zinc-RING finger domain V-set PF07686.12 EMC83059.1 - 1.1e-10 41.3 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC83059.1 - 0.0029 17.6 0.2 0.041 14.0 0.2 2.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC83059.1 - 0.0046 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 EMC83059.1 - 0.014 13.7 0.1 0.047 11.9 0.0 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E I-set PF07679.11 EMC83059.1 - 0.016 15.0 0.0 0.056 13.3 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain TMEM154 PF15102.1 EMC83059.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family V-set PF07686.12 EMC83060.1 - 5.2e-17 61.7 0.5 6.5e-17 61.4 0.4 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC83060.1 - 5.4e-11 42.4 0.4 9.8e-11 41.6 0.3 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC83060.1 - 0.0002 21.1 0.3 0.00038 20.2 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83060.1 - 0.1 13.1 3.5 0.25 11.8 2.4 1.7 1 1 0 1 1 1 0 Immunoglobulin domain TRIQK PF15168.1 EMC83060.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family rve PF00665.21 EMC83061.1 - 8.9e-06 25.8 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain SET PF00856.23 EMC83062.1 - 1.4e-10 41.7 0.0 3.8e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EMC83062.1 - 2.4e-09 36.9 17.5 2.4e-09 36.9 12.2 2.6 3 0 0 3 3 3 1 MYND finger TPR_12 PF13424.1 EMC83062.1 - 0.00085 19.2 0.1 0.003 17.4 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Lipocalin_7 PF14651.1 EMC83063.1 - 1.1e-31 109.1 2.4 1.3e-31 108.9 1.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 EMC83063.1 - 2.7e-17 63.0 1.9 3e-17 62.9 1.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Peptidase_C41 PF05417.6 EMC83063.1 - 0.039 13.4 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease LYTB PF02401.13 EMC83063.1 - 0.046 12.6 0.2 0.055 12.3 0.2 1.1 1 0 0 1 1 1 0 LytB protein Thr_synth_N PF14821.1 EMC83064.1 - 6e-25 87.0 0.2 3e-24 84.8 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus PALP PF00291.20 EMC83064.1 - 1.7e-14 53.7 0.0 4e-14 52.5 0.0 1.5 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Fork_head PF00250.13 EMC83065.1 - 7.8e-38 128.4 0.0 1.2e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Fork head domain HNH_2 PF13391.1 EMC83065.1 - 0.098 12.4 0.2 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease 7tm_1 PF00001.16 EMC83066.1 - 4.4e-70 235.7 27.8 5.1e-70 235.5 19.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83066.1 - 5.1e-09 35.6 32.8 5.8e-08 32.1 22.7 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC83066.1 - 0.46 9.5 30.6 0.77 8.8 20.4 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Pkinase PF00069.20 EMC83067.1 - 2.4e-50 171.0 0.0 7.7e-38 130.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83067.1 - 2.4e-31 108.7 0.0 3.2e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.1 EMC83067.1 - 5.7e-06 25.9 0.1 0.00069 19.1 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Kinase-like PF14531.1 EMC83067.1 - 5.1e-05 22.3 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PQQ PF01011.16 EMC83067.1 - 5.1e-05 22.5 0.0 0.27 10.8 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.9 EMC83067.1 - 0.015 14.4 0.2 0.035 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC83067.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.1 EMC83067.1 - 0.052 13.8 0.4 5.2 7.4 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Rib_5-P_isom_A PF06026.9 EMC83068.1 - 8.5e-65 217.2 0.0 1e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Peptidase_C93 PF06035.6 EMC83068.1 - 0.088 12.2 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP CoA_binding PF02629.14 EMC83070.1 - 1.4e-31 108.8 1.3 2.6e-30 104.7 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EMC83070.1 - 2.5e-23 82.3 0.1 4.1e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EMC83070.1 - 2e-08 33.9 0.0 3.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EMC83070.1 - 2.2e-05 24.5 0.0 5.8e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Vinculin PF01044.14 EMC83071.1 - 4.1e-208 693.7 19.6 4.6e-208 693.5 13.6 1.0 1 0 0 1 1 1 1 Vinculin family HECT PF00632.20 EMC83072.1 - 3.1e-93 312.4 0.1 1.5e-92 310.1 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.2 EMC83072.1 - 3.5e-43 145.8 1.1 1e-18 67.4 0.1 3.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC83072.1 - 4e-40 133.6 10.7 5.6e-09 35.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EMC83072.1 - 7.5e-34 115.5 5.2 1.5e-11 44.4 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC83072.1 - 1.9e-31 104.9 2.2 5.5e-07 29.2 0.0 7.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EMC83072.1 - 2e-28 97.7 9.1 1.2e-10 41.2 0.1 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) CSD PF00313.17 EMC83073.1 - 6.5e-18 64.2 0.1 1.4e-17 63.2 0.1 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.18 EMC83073.1 - 5.4e-07 29.2 14.7 0.00045 20.0 2.6 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EMC83073.1 - 0.00085 18.9 11.1 0.07 12.8 1.5 2.5 2 0 0 2 2 2 2 Zinc knuckle Popeye PF04831.8 EMC83074.1 - 1.9e-72 241.9 0.0 2.6e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.24 EMC83074.1 - 0.014 15.1 0.2 0.14 11.9 0.0 2.6 2 1 0 2 2 2 0 Cyclic nucleotide-binding domain Peptidase_S9_N PF02897.10 EMC83075.1 - 1.4e-158 527.8 0.1 1.6e-158 527.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EMC83075.1 - 1.2e-69 233.7 0.0 1.9e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EMC83075.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase zf-H2C2_2 PF13465.1 EMC83076.1 - 4.7e-28 96.0 46.9 4.5e-08 32.9 0.9 5.7 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC83076.1 - 2.4e-14 52.7 50.4 3e-05 24.0 0.3 5.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83076.1 - 4.3e-13 48.5 42.0 0.0017 18.5 1.3 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger SET PF00856.23 EMC83076.1 - 2.6e-08 34.3 0.2 1.5e-07 31.8 0.1 2.2 1 1 0 1 1 1 1 SET domain zf-C2H2_6 PF13912.1 EMC83076.1 - 2.2e-05 24.2 6.7 0.00034 20.3 1.2 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83076.1 - 0.00011 22.1 30.9 0.0028 17.7 0.3 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC83076.1 - 0.019 15.1 40.5 0.037 14.2 2.2 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EMC83076.1 - 5.4 6.8 35.4 0.24 11.1 5.2 4.8 4 1 1 5 5 5 0 BED zinc finger APG5 PF04106.7 EMC83077.1 - 7.2e-68 227.9 0.2 9.3e-68 227.5 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 MCLC PF05934.6 EMC83078.1 - 0.31 9.3 3.4 0.42 8.8 2.4 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Crystall PF00030.14 EMC83079.1 - 1.2e-126 412.8 1.8 6.6e-27 93.2 0.0 6.3 6 0 0 6 6 6 6 Beta/Gamma crystallin Ricin_B_lectin PF00652.17 EMC83079.1 - 3.5e-14 52.9 0.5 6.9e-14 51.9 0.1 1.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EMC83079.1 - 4.5e-05 23.7 0.0 0.044 14.1 0.0 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Crystall_3 PF08964.5 EMC83079.1 - 0.001 18.7 0.1 0.85 9.3 0.0 4.9 6 1 0 6 6 6 1 Beta/Gamma crystallin Amidase PF01425.16 EMC83080.1 - 1.5e-124 416.2 0.0 9.1e-124 413.6 0.0 1.8 1 1 0 1 1 1 1 Amidase RNA_pol_3_Rpc31 PF11705.3 EMC83081.1 - 0.16 11.9 7.9 0.25 11.2 5.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.1 EMC83081.1 - 0.17 11.5 1.8 0.27 10.9 1.3 1.3 1 0 0 1 1 1 0 FAM176 family BEN PF10523.4 EMC83082.1 - 8.1e-72 237.2 5.9 1.1e-18 67.0 0.1 4.6 4 0 0 4 4 4 4 BEN domain DUF1826 PF08856.6 EMC83082.1 - 0.022 14.4 0.6 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) polyprenyl_synt PF00348.12 EMC83083.1 - 2.5e-14 52.7 0.1 4.2e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase VirK PF06903.7 EMC83083.1 - 0.0097 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 VirK protein SOBP PF15279.1 EMC83084.1 - 1.2e-78 265.6 35.5 1.2e-78 265.6 24.6 3.3 3 0 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.9 EMC83084.1 - 0.00069 19.2 13.9 0.062 12.9 2.0 2.7 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif DUF3588 PF12140.3 EMC83085.1 - 1e-43 148.1 0.7 1.5e-43 147.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 EMC83085.1 - 4.5e-14 52.3 0.1 9.3e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC83085.1 - 0.00032 20.5 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC83085.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sec63 PF02889.11 EMC83086.1 - 9.2e-52 176.2 5.8 8.4e-44 150.0 0.9 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 EMC83086.1 - 3.4e-19 68.3 0.1 9.1e-19 66.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain OSTMP1 PF09777.4 EMC83087.1 - 3.4e-76 255.5 6.6 3.8e-76 255.3 4.6 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.1 EMC83087.1 - 0.00068 19.2 0.1 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family zf-C2H2_6 PF13912.1 EMC83087.1 - 0.29 11.1 1.6 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC83087.1 - 0.46 10.9 0.2 0.46 10.9 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Hormone_recep PF00104.25 EMC83088.1 - 3.2e-33 114.5 0.1 4.7e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC83088.1 - 2.6e-17 62.8 4.6 9.9e-17 60.9 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) C1_2 PF03107.11 EMC83088.1 - 0.37 10.9 2.8 0.94 9.6 1.9 1.7 1 0 0 1 1 1 0 C1 domain AFG1_ATPase PF03969.11 EMC83089.1 - 1.6e-111 372.6 1.9 4.7e-107 357.9 0.3 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EMC83089.1 - 1.2e-05 25.3 0.1 0.0032 17.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 EMC83089.1 - 0.00018 21.7 0.1 0.001 19.2 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EMC83089.1 - 0.00061 19.4 3.3 0.68 9.5 0.3 3.4 3 1 0 3 3 3 2 Bacterial dnaA protein AAA_22 PF13401.1 EMC83089.1 - 0.0023 18.0 0.1 0.017 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EMC83089.1 - 0.0025 17.1 0.1 0.035 13.4 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain NACHT PF05729.7 EMC83089.1 - 0.0045 16.6 0.0 0.026 14.2 0.0 2.2 2 1 1 3 3 3 1 NACHT domain Phostensin_N PF13916.1 EMC83089.1 - 0.054 13.4 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Arch_ATPase PF01637.13 EMC83089.1 - 0.057 13.1 0.8 0.28 10.8 0.1 2.4 2 2 0 2 2 2 0 Archaeal ATPase DUF2075 PF09848.4 EMC83089.1 - 0.072 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SI PF02501.12 EMC83091.1 - 0.11 12.4 0.4 0.17 11.8 0.1 1.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Fork_head PF00250.13 EMC83092.1 - 2.4e-06 27.4 0.2 5.3e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Fork head domain Microvir_lysis PF04517.7 EMC83093.1 - 0.094 12.4 0.9 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Arm PF00514.18 EMC83094.1 - 7.1e-11 41.5 6.0 0.03 14.1 0.0 6.8 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat KAP PF05804.7 EMC83094.1 - 9e-08 30.5 16.2 9.6e-06 23.8 1.4 3.0 3 1 0 3 3 3 2 Kinesin-associated protein (KAP) HEAT_2 PF13646.1 EMC83094.1 - 0.00076 19.7 0.1 1.6 9.0 0.0 4.8 3 3 1 4 4 4 1 HEAT repeats Arm_2 PF04826.8 EMC83094.1 - 0.22 10.5 19.7 0.08 12.0 0.6 4.3 3 2 2 5 5 5 0 Armadillo-like PA26 PF04636.8 EMC83095.1 - 9.2e-223 739.8 2.2 1e-222 739.7 1.5 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.15 EMC83095.1 - 0.0006 19.6 0.0 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cep57_CLD PF14073.1 EMC83096.1 - 3e-61 206.3 39.3 3e-61 206.3 27.3 2.5 2 1 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.8 EMC83096.1 - 3e-19 68.7 4.1 3e-19 68.7 2.8 4.5 2 1 3 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Phage_GP20 PF06810.6 EMC83096.1 - 0.0021 17.5 7.2 0.0021 17.5 5.0 4.4 3 1 2 5 5 5 1 Phage minor structural protein GP20 DUF2522 PF10747.4 EMC83096.1 - 3.1 7.8 16.4 0.3 11.0 3.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2522) MGC-24 PF05283.6 EMC83097.1 - 2.3e-31 109.0 18.8 2.9e-31 108.7 13.0 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) DUF3494 PF11999.3 EMC83097.1 - 0.0033 17.0 4.6 0.004 16.8 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) ABC2_membrane_3 PF12698.2 EMC83097.1 - 0.019 13.9 1.7 0.022 13.7 1.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Alpha_GJ PF03229.8 EMC83097.1 - 0.027 14.7 8.3 0.038 14.3 5.7 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF4366 PF14283.1 EMC83097.1 - 0.055 12.8 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Mucin PF01456.12 EMC83097.1 - 0.16 11.7 27.1 0.19 11.5 18.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pex14_N PF04695.8 EMC83097.1 - 0.79 9.7 3.7 1.4 9.0 2.6 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lamp PF01299.12 EMC83097.1 - 1.4 8.0 15.4 1.7 7.7 10.7 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) zf-H2C2_2 PF13465.1 EMC83098.1 - 2.8e-54 178.8 48.9 1.2e-09 37.9 0.7 9.5 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 EMC83098.1 - 4.4e-38 127.3 62.8 4.1e-07 29.9 0.2 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type BTB PF00651.26 EMC83098.1 - 6.1e-27 93.8 0.3 1.4e-26 92.6 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 EMC83098.1 - 1.2e-23 81.5 52.4 0.00019 21.5 0.2 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83098.1 - 2.5e-15 56.0 39.8 0.022 14.9 1.0 9.4 10 0 0 10 10 9 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC83098.1 - 1.7e-10 40.7 47.6 0.00046 20.2 0.2 8.8 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC83098.1 - 1.8e-08 34.0 45.3 0.055 13.3 0.3 9.2 9 0 0 9 9 8 4 C2H2-type zinc finger zf-Di19 PF05605.7 EMC83098.1 - 4.6e-06 26.6 26.7 0.011 15.9 0.5 5.1 2 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 EMC83098.1 - 0.00033 20.3 23.5 0.084 12.6 0.3 4.8 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 EMC83098.1 - 0.0029 17.7 34.4 0.038 14.2 0.8 7.2 6 0 0 6 6 6 2 C2H2-type zinc-finger domain DUF2180 PF09947.4 EMC83098.1 - 0.053 13.2 10.8 4.5 7.0 0.1 4.8 2 2 3 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2HC_2 PF13913.1 EMC83098.1 - 0.12 12.0 0.1 0.12 12.0 0.0 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type AT_hook PF02178.14 EMC83098.1 - 0.23 11.2 6.4 0.7 9.7 4.4 1.8 1 0 0 1 1 1 0 AT hook motif XPA_N PF01286.13 EMC83098.1 - 1 9.1 30.1 3.2 7.5 0.3 6.7 7 0 0 7 7 7 0 XPA protein N-terminal RRN7 PF11781.3 EMC83098.1 - 1.1 8.7 16.7 24 4.5 0.0 6.7 8 0 0 8 8 8 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-FCS PF06467.9 EMC83098.1 - 2.1 8.0 29.8 0.56 9.8 0.4 6.3 3 2 3 6 6 6 0 MYM-type Zinc finger with FCS sequence motif C1_4 PF07975.7 EMC83098.1 - 3.5 7.7 28.5 3.9 7.5 0.6 5.4 3 1 1 5 5 5 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 EMC83098.1 - 5.8 6.7 34.1 3.4 7.5 2.4 6.0 5 1 1 6 6 6 0 Transposase zinc-ribbon domain ADK PF00406.17 EMC83099.1 - 3.6e-18 65.8 0.0 6.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase YHS PF04945.8 EMC83099.1 - 2.6e-10 39.9 2.0 0.0067 16.2 0.0 3.5 3 0 0 3 3 3 3 YHS domain AAA_17 PF13207.1 EMC83099.1 - 2e-09 38.2 0.0 6.2e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF3508 PF12018.3 EMC83099.1 - 1.9e-05 23.7 1.1 0.0016 17.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3508) AAA_18 PF13238.1 EMC83099.1 - 0.00047 20.4 0.5 0.0057 16.9 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMC83099.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMC83099.1 - 0.0053 16.6 0.1 0.031 14.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC83099.1 - 0.039 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMC83099.1 - 0.043 13.7 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMC83099.1 - 0.049 13.3 0.1 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EMC83099.1 - 0.065 12.7 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.17 EMC83100.1 - 2.8e-11 43.4 0.1 7.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 EMC83100.1 - 4.9e-08 33.8 0.2 3.4e-07 31.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EMC83100.1 - 3.3e-06 27.4 0.5 4e-05 23.9 0.4 2.5 1 1 0 1 1 1 1 AAA domain YHS PF04945.8 EMC83100.1 - 3.6e-05 23.5 4.4 5.2e-05 22.9 1.0 2.6 3 0 0 3 3 2 1 YHS domain AAA_28 PF13521.1 EMC83100.1 - 0.00015 21.7 0.1 0.00042 20.3 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EMC83100.1 - 0.00026 21.1 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMC83100.1 - 0.00045 20.1 0.0 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC83100.1 - 0.0035 16.4 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF3508 PF12018.3 EMC83100.1 - 0.0046 15.9 2.9 0.0056 15.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3508) UPF0079 PF02367.12 EMC83100.1 - 0.0087 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EMC83100.1 - 0.011 15.4 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EMC83100.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMC83100.1 - 0.013 15.7 0.1 0.028 14.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EMC83100.1 - 0.016 14.7 0.1 0.035 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain SKI PF01202.17 EMC83100.1 - 0.017 15.0 0.7 0.036 13.9 0.0 1.9 3 0 0 3 3 3 0 Shikimate kinase NB-ARC PF00931.17 EMC83100.1 - 0.021 13.7 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EMC83100.1 - 0.032 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EMC83100.1 - 0.044 13.6 1.4 0.13 12.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EMC83100.1 - 0.05 13.5 0.3 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family RNA_helicase PF00910.17 EMC83100.1 - 0.054 13.6 0.1 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase IncA PF04156.9 EMC83100.1 - 5.5 6.5 6.3 1.3 8.5 1.5 1.8 2 0 0 2 2 2 0 IncA protein zf-ribbon_3 PF13248.1 EMC83101.1 - 0.16 11.1 4.0 0.44 9.8 1.6 2.7 2 1 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 EMC83101.1 - 0.74 9.5 15.5 0.83 9.3 8.4 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 EMC83101.1 - 1 9.0 2.9 0.86 9.3 0.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain 7tm_1 PF00001.16 EMC83102.1 - 7.5e-13 48.2 1.5 8.4e-13 48.0 1.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIF4G PF02854.14 EMC83103.1 - 1e-16 60.9 2.0 1.6e-16 60.3 1.4 1.3 1 0 0 1 1 1 1 MIF4G domain MH1 PF03165.11 EMC83104.1 - 9.5e-20 70.5 7.0 1.2e-19 70.1 4.8 1.1 1 0 0 1 1 1 1 MH1 domain Dymeclin PF09742.4 EMC83105.1 - 4.2e-189 629.9 12.2 6.3e-189 629.3 8.4 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 EMC83105.1 - 1.8e-08 32.6 14.2 4e-08 31.4 9.8 1.5 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein TLV_coat PF00429.14 EMC83106.1 - 7.4e-103 344.9 0.2 8.6e-103 344.6 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) IncA PF04156.9 EMC83106.1 - 0.022 14.3 0.2 0.022 14.3 0.1 2.0 2 0 0 2 2 2 0 IncA protein PhnA_Zn_Ribbon PF08274.7 EMC83106.1 - 0.028 14.1 0.0 0.079 12.7 0.0 1.8 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF4512 PF14975.1 EMC83107.1 - 2.6e-18 66.6 0.6 2.9e-18 66.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Ribosomal_L22 PF00237.14 EMC83108.1 - 3.9e-38 129.5 0.1 6.2e-38 128.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Lipase PF00151.14 EMC83109.1 - 9.7e-72 241.9 0.0 1.9e-71 240.9 0.0 1.5 2 0 0 2 2 2 1 Lipase PLAT PF01477.18 EMC83109.1 - 1.2e-18 67.4 1.2 2.5e-18 66.5 0.1 2.0 2 1 0 2 2 2 1 PLAT/LH2 domain Thiolase_N PF00108.18 EMC83110.1 - 4.2e-93 311.1 0.1 6.2e-93 310.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC83110.1 - 2.1e-52 175.6 0.4 4.4e-52 174.6 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMC83110.1 - 0.0025 17.3 0.4 0.046 13.1 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain zf-C4H2 PF10146.4 EMC83111.1 - 5.8e-87 291.5 22.5 6.7e-87 291.3 15.6 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein Sec20 PF03908.8 EMC83111.1 - 0.01 15.4 4.3 0.013 15.2 0.2 2.2 1 1 1 2 2 2 0 Sec20 DZR PF12773.2 EMC83111.1 - 0.011 15.4 1.6 0.024 14.4 1.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon BLOC1_2 PF10046.4 EMC83111.1 - 0.046 13.8 9.1 1.5 9.0 0.3 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lipoprotein_7 PF01540.11 EMC83111.1 - 0.048 12.7 5.1 0.075 12.0 3.5 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein zf-P11 PF03854.9 EMC83111.1 - 0.075 12.5 2.3 0.15 11.5 1.6 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.1 EMC83111.1 - 0.091 12.4 4.2 0.16 11.6 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMC83111.1 - 0.1 12.1 2.8 0.21 11.1 1.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Polysacc_synt_4 PF04669.8 EMC83111.1 - 0.24 10.7 2.5 0.4 10.0 1.8 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis Spc7 PF08317.6 EMC83111.1 - 0.49 9.0 13.5 0.63 8.6 9.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4041 PF13250.1 EMC83111.1 - 0.51 9.9 2.9 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) TMF_TATA_bd PF12325.3 EMC83111.1 - 0.72 9.5 19.9 2.4 7.9 6.9 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 EMC83111.1 - 0.88 9.3 5.5 1.8 8.4 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Tup_N PF08581.5 EMC83111.1 - 1.7 8.9 14.3 0.86 9.8 5.1 2.8 1 1 1 2 2 2 0 Tup N-terminal DUF3450 PF11932.3 EMC83111.1 - 2 7.6 17.7 0.14 11.3 2.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 EMC83111.1 - 2.4 8.5 17.0 3.6 7.9 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) WAC_Acf1_DNA_bd PF10537.4 EMC83111.1 - 2.9 8.0 5.6 5.2 7.2 0.8 2.4 1 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal HALZ PF02183.13 EMC83111.1 - 4 7.2 15.3 2.6 7.8 2.6 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper RNase_Zc3h12a PF11977.3 EMC83112.1 - 4.7e-63 211.6 0.0 7.5e-63 211.0 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 PF14608.1 EMC83112.1 - 1.3 9.0 10.0 3.7 7.6 6.9 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Pol_alpha_B_N PF08418.5 EMC83112.1 - 7.2 6.0 9.4 0.45 10.0 2.8 1.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF2890 PF11081.3 EMC83113.1 - 0.77 9.7 4.2 1.1 9.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Las1 PF04031.8 EMC83114.1 - 2.7e-35 121.3 0.0 3.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Las1-like BTB_2 PF02214.17 EMC83115.1 - 7.9e-25 86.9 0.0 1.3e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 EMC83115.1 - 2.3e-20 72.7 15.6 2.3e-20 72.7 10.8 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EMC83115.1 - 4.4e-10 39.1 8.1 4.4e-10 39.1 5.6 2.4 3 0 0 3 3 3 1 Ion channel ATP1G1_PLM_MAT8 PF02038.11 EMC83115.1 - 0.15 11.0 4.4 0.13 11.2 0.2 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family ERM PF00769.14 EMC83117.1 - 3e-73 246.3 68.1 3e-73 246.3 47.2 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.5 EMC83117.1 - 5.7e-33 112.9 0.0 1.7e-32 111.4 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 EMC83117.1 - 8.3e-26 90.6 0.4 8.3e-26 90.6 0.3 4.0 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.5 EMC83117.1 - 5.4e-19 68.0 0.2 5.4e-19 68.0 0.1 3.2 3 0 0 3 3 3 1 FERM N-terminal domain Fer2 PF00111.22 EMC83118.1 - 2.2e-08 33.7 0.2 2.9e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-set PF07686.12 EMC83120.1 - 9.2e-17 60.9 0.1 7.7e-10 38.6 0.0 3.2 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC83120.1 - 3.5e-13 49.4 0.1 6.5e-06 26.1 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC83120.1 - 1.9e-12 46.8 0.0 9.3e-05 22.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83120.1 - 1.3e-11 44.7 1.6 8.3e-06 26.2 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC83120.1 - 2.3e-10 40.4 0.2 0.00081 19.4 0.2 3.2 2 1 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.6 EMC83120.1 - 0.076 12.7 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Cu-oxidase_2 PF07731.9 EMC83121.1 - 2.6e-26 91.7 10.4 2.4e-11 43.2 1.3 6.2 5 2 0 5 5 5 5 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMC83121.1 - 2.9e-24 85.0 0.1 8.4e-08 31.9 0.0 5.6 6 0 0 6 6 6 3 Multicopper oxidase 7tm_1 PF00001.16 EMC83122.1 - 3e-51 174.0 24.0 3e-51 174.0 16.7 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83122.1 - 9.3e-10 38.0 23.6 1.3e-09 37.6 16.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 EMC83124.1 - 2.2e-59 200.7 22.7 3.1e-59 200.2 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83124.1 - 2.7e-15 56.2 20.8 3.3e-15 55.9 14.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MP PF01107.13 EMC83124.1 - 0.047 13.0 0.5 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Viral movement protein (MP) DUF2109 PF09882.4 EMC83124.1 - 2.8 7.9 10.9 0.33 10.9 1.5 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2109) Hormone_recep PF00104.25 EMC83125.1 - 1.9e-31 108.7 2.5 3.4e-31 107.9 1.7 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC83125.1 - 1.2e-27 95.9 14.4 2.2e-27 95.0 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Yip1 PF04893.12 EMC83126.1 - 4.8e-19 68.4 12.3 4.8e-19 68.4 8.5 1.7 1 1 0 1 1 1 1 Yip1 domain CobD_Cbib PF03186.8 EMC83126.1 - 0.19 10.7 2.2 0.31 10.0 1.5 1.2 1 0 0 1 1 1 0 CobD/Cbib protein START PF01852.14 EMC83127.1 - 6e-39 133.5 0.1 1.2e-38 132.5 0.1 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.22 EMC83127.1 - 1.7e-35 121.8 0.1 3.6e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Ephrin PF00812.12 EMC83129.1 - 1.3e-25 89.5 0.1 1.9e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Ephrin Spore_coat_CotO PF14153.1 EMC83130.1 - 2.3e-05 23.9 28.3 3.3e-05 23.3 19.6 1.4 1 0 0 1 1 1 1 Spore coat protein CotO Caldesmon PF02029.10 EMC83130.1 - 6e-05 21.6 34.0 7.3e-05 21.3 23.5 1.2 1 0 0 1 1 1 1 Caldesmon CDC45 PF02724.9 EMC83130.1 - 0.00047 18.3 27.0 0.0006 17.9 18.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 EMC83130.1 - 0.0011 16.9 48.6 0.0015 16.5 33.7 1.1 1 0 0 1 1 1 1 Nop14-like family MIP-T3 PF10243.4 EMC83130.1 - 0.0017 16.9 39.1 0.0021 16.6 27.1 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SDA1 PF05285.7 EMC83130.1 - 0.014 14.6 46.9 0.019 14.2 32.5 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.10 EMC83130.1 - 0.033 12.8 16.7 0.036 12.7 11.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EMC83130.1 - 0.052 11.2 25.1 0.065 10.9 17.4 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 EMC83130.1 - 0.71 9.8 31.5 1.3 9.0 21.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4045 PF13254.1 EMC83130.1 - 0.95 8.6 22.3 1.7 7.8 15.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SprA-related PF12118.3 EMC83130.1 - 1.2 8.4 28.3 2.3 7.4 19.6 1.5 1 0 0 1 1 1 0 SprA-related family DUF1510 PF07423.6 EMC83130.1 - 2.5 7.3 48.8 3.7 6.8 33.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PLRV_ORF5 PF01690.12 EMC83130.1 - 2.7 7.0 21.7 3.7 6.5 15.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NPR3 PF03666.8 EMC83130.1 - 6.7 5.1 17.3 9.8 4.5 12.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.2 EMC83130.1 - 7.1 4.1 19.2 8.8 3.8 13.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TNF PF00229.13 EMC83132.1 - 1.3e-17 63.5 0.1 1.8e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 EMC83132.1 - 1e-09 37.7 67.3 1.4e-07 30.9 23.6 2.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) LRR_8 PF13855.1 EMC83134.1 - 1.4e-61 204.1 49.4 1e-11 44.3 2.1 9.0 7 1 2 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 EMC83134.1 - 4.4e-48 160.2 54.2 2.7e-06 26.8 0.0 11.7 9 2 0 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC83134.1 - 6.3e-35 113.8 57.3 0.058 13.4 0.0 19.5 20 0 0 20 20 20 12 Leucine Rich Repeat LRR_6 PF13516.1 EMC83134.1 - 6e-16 56.6 56.9 3.8 7.8 0.0 18.7 19 1 1 20 20 20 6 Leucine Rich repeat LRR_7 PF13504.1 EMC83134.1 - 8.3e-13 46.2 72.4 1.2 9.6 0.1 19.5 19 1 1 20 20 20 4 Leucine rich repeat LRR_9 PF14580.1 EMC83134.1 - 1.6e-05 24.5 4.4 0.24 10.9 0.0 5.2 4 2 2 5 5 5 3 Leucine-rich repeat LRR_5 PF13306.1 EMC83134.1 - 0.00012 21.7 0.0 0.38 10.4 0.0 3.6 4 0 0 4 4 4 2 Leucine rich repeats (6 copies) wnt PF00110.14 EMC83135.1 - 3.5e-108 361.4 8.8 4e-108 361.2 6.1 1.0 1 0 0 1 1 1 1 wnt family TAP42 PF04177.7 EMC83136.1 - 2.1e-74 250.4 0.0 4.2e-74 249.5 0.0 1.5 1 1 0 1 1 1 1 TAP42-like family Ribosomal_60s PF00428.14 EMC83136.1 - 4.6 7.6 9.0 0.19 12.1 0.4 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein DAGAT PF03982.8 EMC83137.1 - 1.3e-116 388.4 0.0 1.6e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF2852 PF11014.3 EMC83137.1 - 7.6 6.5 9.2 11 6.0 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) 7tm_1 PF00001.16 EMC83138.1 - 1.6e-51 174.9 24.7 1.8e-51 174.7 17.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 EMC83138.1 - 0.0028 17.4 4.0 0.0028 17.4 2.8 2.3 1 1 1 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa COX7C PF02935.11 EMC83138.1 - 0.12 12.2 2.6 5.6 6.8 0.2 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc PalH PF08733.5 EMC83138.1 - 0.13 11.0 9.8 0.0084 14.9 2.9 1.7 1 1 0 1 1 1 0 PalH/RIM21 Sigma_reg_N PF13800.1 EMC83138.1 - 0.42 10.6 11.1 0.036 14.0 1.5 3.2 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Arrestin_N PF00339.24 EMC83140.1 - 4.8e-39 133.5 0.1 2.6e-34 118.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMC83140.1 - 1.4e-25 90.0 1.4 2.3e-25 89.3 0.9 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain BatD PF13584.1 EMC83140.1 - 0.0044 15.6 0.3 0.0061 15.2 0.2 1.2 1 0 0 1 1 1 1 Oxygen tolerance Glyco_hydro_66 PF13199.1 EMC83140.1 - 0.023 13.0 0.7 0.029 12.7 0.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 DUF974 PF06159.8 EMC83140.1 - 0.051 13.0 0.2 0.086 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF974) CBM49 PF09478.5 EMC83140.1 - 0.15 12.1 1.2 0.27 11.3 0.8 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 VirDNA-topo-I_N PF09266.5 EMC83140.1 - 0.41 10.5 4.7 0.52 10.2 1.8 2.2 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal Ras PF00071.17 EMC83141.1 - 4.6e-28 97.6 0.1 5e-28 97.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83141.1 - 1.1e-12 48.5 0.0 1.2e-12 48.4 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83141.1 - 5.1e-07 29.1 0.1 5.4e-07 29.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC83141.1 - 0.00024 20.3 0.0 0.00028 20.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC83141.1 - 0.0087 16.0 0.0 0.0098 15.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC83141.1 - 0.01 14.9 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC83141.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Kinesin PF00225.18 EMC83143.1 - 1.1e-114 382.5 0.0 1.1e-114 382.5 0.0 3.2 3 1 0 3 3 3 1 Kinesin motor domain Collagen PF01391.13 EMC83144.1 - 4.8e-17 61.2 33.2 3.8e-08 32.7 6.3 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) SLAIN PF15301.1 EMC83146.1 - 1.2e-144 482.0 26.1 1.4e-144 481.8 18.1 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family 7tm_1 PF00001.16 EMC83147.1 - 3.5e-42 144.3 11.3 3.5e-42 144.3 7.9 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83147.1 - 5.4e-10 38.8 11.3 1.3e-09 37.5 7.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC83147.1 - 4.3e-05 22.7 9.6 4.9e-05 22.5 4.7 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Yae1_N PF09811.4 EMC83148.1 - 1.9e-08 33.6 24.2 0.069 12.6 16.8 2.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal BRCA-2_OB3 PF09104.5 EMC83149.1 - 0.00094 19.0 0.3 0.0019 17.9 0.2 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF904 PF06005.7 EMC83149.1 - 0.0082 16.4 8.7 0.02 15.1 1.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EMC83149.1 - 0.028 14.3 12.2 0.4 10.6 1.0 2.6 2 0 0 2 2 2 0 bZIP transcription factor ERM PF00769.14 EMC83149.1 - 0.045 13.2 11.0 0.094 12.2 7.6 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PEP-utilisers_N PF05524.8 EMC83149.1 - 0.066 13.0 1.4 0.14 11.9 1.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PspA_IM30 PF04012.7 EMC83149.1 - 0.41 9.9 13.0 0.82 8.9 9.0 1.5 1 1 0 1 1 1 0 PspA/IM30 family HALZ PF02183.13 EMC83149.1 - 1 9.1 8.9 0.2 11.3 2.8 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF2205 PF10224.4 EMC83149.1 - 2.2 7.9 9.9 3 7.4 2.1 2.6 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) TSC22 PF01166.13 EMC83149.1 - 2.3 8.2 14.5 0.38 10.7 1.8 3.8 3 1 1 4 4 4 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 EMC83149.1 - 2.6 5.7 4.8 3.3 5.4 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 EMC83149.1 - 2.9 7.9 11.8 4.8 7.2 3.4 2.4 2 0 0 2 2 2 0 DivIVA protein DUF972 PF06156.8 EMC83149.1 - 3.9 7.8 13.5 2.2 8.6 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Bap31 PF05529.7 EMC83149.1 - 9 5.6 8.6 3.6 6.9 3.8 1.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like RVT_3 PF13456.1 EMC83151.1 - 0.00071 19.3 4.7 99 2.8 0.0 7.1 9 0 0 9 9 9 4 Reverse transcriptase-like SSF PF00474.12 EMC83154.1 - 4.9e-24 84.7 0.1 5e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Yeast_MT PF11403.3 EMC83154.1 - 0.05 13.7 0.5 0.064 13.4 0.4 1.1 1 0 0 1 1 1 0 Yeast metallothionein SSF PF00474.12 EMC83155.1 - 9.4e-78 261.6 12.6 1.1e-77 261.3 8.7 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Spore_permease PF03845.8 EMC83155.1 - 0.0039 15.8 13.0 0.0039 15.8 9.0 1.4 2 0 0 2 2 2 1 Spore germination protein FH2 PF02181.18 EMC83156.1 - 3.3e-58 197.3 5.9 3.7e-58 197.1 4.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DNA_pack_N PF02500.10 EMC83156.1 - 0.51 9.8 5.2 0.39 10.2 0.2 2.1 1 1 0 2 2 2 0 Probable DNA packing protein, N-terminus zf-DHHC PF01529.15 EMC83157.1 - 2.9e-31 108.2 7.4 2.9e-31 108.2 5.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-C2H2 PF00096.21 EMC83158.1 - 1.1e-39 132.4 73.3 0.0001 22.4 1.0 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC83158.1 - 4.8e-38 127.6 78.1 5.6e-08 32.6 1.1 11.0 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC83158.1 - 1.9e-33 112.2 56.9 0.00068 19.7 0.1 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83158.1 - 2.4e-23 81.6 36.3 3e-05 24.0 0.3 10.4 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC83158.1 - 6.1e-13 48.1 58.3 7.3e-07 28.8 1.7 9.9 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC83158.1 - 7.8e-06 25.4 34.9 0.24 11.1 0.2 8.4 8 0 0 8 8 8 3 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.2 EMC83158.1 - 0.00094 18.9 49.7 0.0051 16.5 1.5 7.0 5 2 1 6 6 5 4 Transposase zinc-ribbon domain zf-met PF12874.2 EMC83158.1 - 0.00097 19.2 0.5 0.00097 19.2 0.4 8.5 9 0 0 9 9 9 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EMC83158.1 - 0.0015 18.3 49.1 1 9.3 2.5 9.8 8 2 1 9 9 9 3 Zinc ribbon domain zf-C2H2_2 PF12756.2 EMC83158.1 - 0.0041 17.1 43.5 0.26 11.4 0.1 8.9 3 2 7 10 10 10 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EMC83158.1 - 0.035 14.2 38.9 0.36 11.0 0.2 7.2 4 2 1 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EMC83158.1 - 0.06 13.3 21.1 1.5 8.8 0.0 7.3 7 0 0 7 7 7 0 zinc-finger XPA_N PF01286.13 EMC83158.1 - 0.062 12.9 0.4 0.062 12.9 0.3 7.3 9 0 0 9 9 8 0 XPA protein N-terminal zf-piccolo PF05715.8 EMC83158.1 - 0.73 9.8 7.5 6.6 6.8 0.1 3.4 3 0 0 3 3 3 0 Piccolo Zn-finger C1_1 PF00130.17 EMC83158.1 - 6.6 6.5 34.3 0.79 9.5 0.1 7.3 3 2 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BRICHOS PF04089.9 EMC83159.1 - 1.4e-10 40.8 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain WD40 PF00400.27 EMC83160.1 - 3.8e-39 131.1 4.9 1.8e-08 33.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Hira PF07569.6 EMC83160.1 - 0.00044 19.5 0.1 0.14 11.3 0.0 2.7 1 1 1 2 2 2 2 TUP1-like enhancer of split Nup160 PF11715.3 EMC83160.1 - 0.00071 17.8 0.7 0.11 10.6 0.7 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EMC83160.1 - 0.0034 15.2 0.1 0.36 8.5 0.0 2.3 2 0 0 2 2 2 2 IKI3 family DUF2415 PF10313.4 EMC83160.1 - 0.085 12.5 0.1 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF3312 PF11768.3 EMC83160.1 - 0.13 10.4 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Glyco_hydro_20 PF00728.17 EMC83162.1 - 8.2e-16 58.1 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF1146 PF06612.6 EMC83162.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) ACCA PF03255.9 EMC83162.1 - 0.15 11.6 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit WD40 PF00400.27 EMC83163.1 - 1.3e-46 154.8 28.6 4.6e-11 42.1 1.0 8.3 9 0 0 9 9 8 7 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 EMC83163.1 - 3.4e-06 26.9 10.4 3.4e-06 26.9 7.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EMC83163.1 - 6.4e-06 25.9 9.9 0.0012 18.5 0.5 2.5 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.13 EMC83163.1 - 1.1e-05 25.7 6.1 1.1e-05 25.7 4.2 2.8 3 1 0 3 3 2 1 TRAF-type zinc finger zf-C3HC4 PF00097.20 EMC83163.1 - 3.8e-05 23.2 10.3 3.8e-05 23.2 7.1 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC83163.1 - 0.00012 21.8 7.5 0.00012 21.8 5.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EMC83163.1 - 0.00019 21.0 11.8 0.00093 18.8 8.1 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Nup160 PF11715.3 EMC83163.1 - 0.00061 18.0 7.2 0.0015 16.7 0.2 3.4 3 2 0 4 4 4 1 Nucleoporin Nup120/160 zf-RING_5 PF14634.1 EMC83163.1 - 0.0023 17.6 13.5 0.0023 17.6 9.4 3.0 2 0 0 2 2 2 1 zinc-RING finger domain PQQ_3 PF13570.1 EMC83163.1 - 0.014 15.6 1.7 2.1 8.7 0.0 4.5 5 1 0 5 5 5 0 PQQ-like domain DUF4164 PF13747.1 EMC83163.1 - 0.015 15.4 2.9 0.028 14.5 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Bacillus_HBL PF05791.6 EMC83163.1 - 0.016 14.6 2.0 0.029 13.7 1.4 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.16 EMC83163.1 - 0.067 12.6 3.6 0.1 12.0 2.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein CorA PF01544.13 EMC83163.1 - 0.076 12.0 0.6 0.14 11.1 0.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.7 EMC83163.1 - 0.078 12.7 2.7 0.45 10.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 EMC83163.1 - 0.086 12.6 3.2 0.14 11.9 2.2 1.3 1 0 0 1 1 1 0 Tropomyosin like PQQ_2 PF13360.1 EMC83163.1 - 0.1 12.0 0.4 0.61 9.4 0.2 2.2 1 1 0 2 2 2 0 PQQ-like domain HSBP1 PF06825.7 EMC83163.1 - 0.2 11.2 2.6 0.44 10.1 1.8 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 zf-Nse PF11789.3 EMC83163.1 - 0.38 10.2 10.7 0.22 11.0 3.8 2.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Ras PF00071.17 EMC83164.1 - 1.7e-59 199.8 0.2 2e-59 199.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83164.1 - 1.7e-18 67.2 0.0 3.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83164.1 - 2.3e-14 53.0 0.1 2.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC83164.1 - 5.5e-07 28.9 0.0 7.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC83164.1 - 5e-05 22.8 0.2 0.00011 21.6 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMC83164.1 - 0.00051 19.3 0.1 0.0032 16.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EMC83164.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC83164.1 - 0.0024 17.0 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMC83164.1 - 0.028 14.5 0.1 0.1 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EMC83164.1 - 0.029 13.3 0.1 0.085 11.8 0.1 1.7 1 1 0 1 1 1 0 Septin DUF258 PF03193.11 EMC83164.1 - 0.031 13.4 0.1 0.081 12.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EMC83164.1 - 0.038 13.4 0.0 0.064 12.7 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EMC83164.1 - 0.057 13.6 0.1 0.67 10.1 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMC83164.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EMC83164.1 - 0.087 12.8 0.2 0.13 12.2 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain Ser_hydrolase PF06821.8 EMC83164.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase AAA_24 PF13479.1 EMC83164.1 - 0.1 12.1 0.1 0.27 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain HhH-GPD PF00730.20 EMC83166.1 - 2.1e-19 69.8 0.0 3.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMC83166.1 - 2.9e-09 36.1 0.0 5.4e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EMC83166.1 - 0.14 12.4 6.0 0.22 11.7 4.2 1.3 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III EBP50_C-term PF09007.6 EMC83167.1 - 3.7e-23 81.0 1.9 6.3e-23 80.3 1.3 1.4 1 0 0 1 1 1 1 EBP50, C-terminal PDZ PF00595.19 EMC83167.1 - 8.4e-15 54.7 0.1 5.2e-14 52.1 0.0 2.3 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC83167.1 - 1.3e-06 28.1 0.1 6.9e-06 25.8 0.0 2.2 1 1 1 2 2 2 1 PDZ domain GRASP55_65 PF04495.9 EMC83167.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Peptidase_C54 PF03416.14 EMC83168.1 - 3.6e-112 374.0 0.0 4.3e-112 373.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Ank PF00023.25 EMC83169.1 - 3.9e-44 146.2 4.2 1.3e-10 40.5 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMC83169.1 - 2.8e-38 130.1 4.3 4.6e-19 68.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC83169.1 - 3.9e-38 128.6 10.2 7.1e-14 51.5 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC83169.1 - 1e-33 115.0 2.7 1.5e-13 50.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC83169.1 - 2.7e-32 107.5 2.3 1.1e-07 31.4 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat AMNp_N PF10423.4 EMC83169.1 - 0.053 13.1 0.0 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus V-set PF07686.12 EMC83170.1 - 4.6e-22 78.0 5.2 1.4e-20 73.3 0.4 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 EMC83170.1 - 8.3e-15 54.4 0.0 2.7e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83170.1 - 2.8e-14 53.3 8.6 3.1e-06 27.5 2.9 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC83170.1 - 5.3e-14 52.1 3.1 5.3e-06 26.4 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 EMC83170.1 - 1.6e-08 33.2 0.0 0.00025 19.4 0.0 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E ig PF00047.20 EMC83170.1 - 5.8e-08 32.7 6.5 1.4e-05 25.1 1.9 2.9 2 1 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.6 EMC83170.1 - 0.0055 16.4 1.8 0.0061 16.3 0.1 1.9 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Syndecan PF01034.15 EMC83170.1 - 0.0086 15.7 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Syndecan domain TraL PF07178.6 EMC83170.1 - 0.037 14.0 0.3 0.089 12.8 0.2 1.5 1 0 0 1 1 1 0 TraL protein Vpu PF00558.14 EMC83170.1 - 0.038 13.5 0.2 0.068 12.7 0.1 1.3 1 0 0 1 1 1 0 Vpu protein EphA2_TM PF14575.1 EMC83170.1 - 0.04 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMC83170.1 - 0.056 13.6 0.2 0.099 12.8 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FixQ PF05545.6 EMC83170.1 - 0.15 11.7 0.2 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ C2 PF00168.25 EMC83171.1 - 3.4e-34 116.5 1.8 3.4e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 C2 domain Ras PF00071.17 EMC83172.1 - 6.2e-22 77.7 0.0 6.7e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83172.1 - 3.5e-07 30.7 0.0 3.9e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83172.1 - 5.6e-05 22.4 0.0 5.9e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC83172.1 - 0.00087 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC83172.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Prefoldin PF02996.12 EMC83173.1 - 9.7e-37 125.2 0.2 1.5e-36 124.6 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EMC83173.1 - 0.00013 21.6 3.8 0.051 13.3 0.0 2.3 2 0 0 2 2 2 2 Prefoldin subunit MRL1 PF13003.2 EMC83173.1 - 0.0096 15.7 0.2 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L1 ANTH PF07651.11 EMC83174.1 - 1e-77 260.6 1.1 1.5e-77 260.0 0.7 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EMC83174.1 - 2e-13 50.3 0.2 5.1e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 ENTH domain GST_N_3 PF13417.1 EMC83174.1 - 0.087 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RPA_C PF08784.6 EMC83174.1 - 0.11 12.9 0.1 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 Replication protein A C terminal T2SM PF04612.7 EMC83174.1 - 1.6 8.4 6.0 2.8 7.7 3.5 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M PH PF00169.24 EMC83175.1 - 5.8e-17 61.7 0.4 2.4e-16 59.8 0.3 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EMC83175.1 - 6.8e-05 23.0 5.2 0.00052 20.2 3.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EMC83175.1 - 0.0082 16.0 0.3 0.021 14.7 0.2 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 EMC83175.1 - 0.024 14.8 0.1 0.058 13.5 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.1 EMC83175.1 - 0.39 10.6 2.8 3 7.7 2.0 2.2 1 1 0 1 1 1 0 PH domain SNF2_N PF00176.18 EMC83176.1 - 4.7e-86 288.2 0.2 7.7e-86 287.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EMC83176.1 - 3.8e-44 149.1 5.5 4.3e-44 149.0 2.2 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EMC83176.1 - 7e-27 94.0 2.0 7e-27 94.0 1.4 3.4 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 EMC83176.1 - 3.3e-18 65.3 0.0 2.1e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC83176.1 - 2.8e-08 33.8 1.7 1e-06 28.6 0.0 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC83176.1 - 5.3e-08 32.5 0.0 3.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.1 EMC83176.1 - 2.6e-05 24.3 0.1 2.6e-05 24.3 0.1 5.1 6 0 0 6 6 6 1 DNA-binding domain Myb_DNA-binding PF00249.26 EMC83176.1 - 0.00063 19.7 0.0 0.72 9.9 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain cNMP_binding PF00027.24 EMC83177.1 - 0.04 13.7 0.1 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Ten_N PF06484.7 EMC83178.1 - 9.6e-07 28.2 1.6 1.1e-06 28.0 1.1 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region Histone PF00125.19 EMC83179.1 - 7.6e-18 64.4 0.1 5.6e-17 61.6 0.1 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC83179.1 - 0.0076 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 EMC83180.1 - 1.3e-60 204.7 0.0 1.8e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83180.1 - 5.1e-39 133.8 0.0 7.2e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 EMC83180.1 - 4.7e-13 48.6 0.0 1.2e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 EMC83180.1 - 0.0004 19.4 0.0 0.0076 15.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EMC83180.1 - 0.041 12.7 0.2 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Thiolase_N PF00108.18 EMC83181.1 - 1.2e-80 270.3 1.4 1.9e-80 269.6 1.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC83181.1 - 1.4e-51 173.0 0.3 3e-51 171.9 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EMC83181.1 - 3.3e-06 27.0 0.0 1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EMC83181.1 - 0.00027 20.5 1.4 0.061 12.9 0.1 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EMC83181.1 - 0.0017 17.8 1.2 0.0047 16.4 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PapD-like PF14874.1 EMC83182.1 - 0.012 15.5 1.3 3.2 7.7 0.0 3.4 4 0 0 4 4 4 0 Flagellar-associated PapD-like MYCBPAP PF14646.1 EMC83182.1 - 0.27 9.9 1.2 6.8 5.2 0.0 2.8 3 0 0 3 3 3 0 MYCBP-associated protein family NIF PF03031.13 EMC83183.1 - 6.8e-51 172.0 0.0 9.3e-51 171.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UQ_con PF00179.21 EMC83184.1 - 4.6e-43 146.0 0.0 5e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC83184.1 - 2.9e-05 23.8 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC83184.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC83184.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.21 EMC83185.1 - 1.4e-46 157.3 0.0 2.3e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC83185.1 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC83185.1 - 0.0007 19.4 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain SR-25 PF10500.4 EMC83185.1 - 0.3 10.5 13.1 0.41 10.0 9.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4603 PF15376.1 EMC83185.1 - 7.1 3.6 10.2 8.8 3.3 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Ras PF00071.17 EMC83186.1 - 2.6e-26 91.9 0.3 2.9e-26 91.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83186.1 - 1.6e-17 64.0 0.1 2.4e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83186.1 - 5e-09 35.6 0.2 6.6e-09 35.2 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC83186.1 - 0.00048 20.0 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC83186.1 - 0.00075 18.9 1.1 0.08 12.3 0.8 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EMC83186.1 - 0.00089 19.1 0.1 0.0026 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EMC83186.1 - 0.021 14.6 0.4 0.26 11.1 0.3 2.6 1 1 0 1 1 1 0 Dynamin family FeoB_N PF02421.13 EMC83186.1 - 0.047 12.9 0.1 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 EMC83186.1 - 0.18 11.9 0.8 0.94 9.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain Ribosomal_L15e PF00827.12 EMC83187.1 - 3.1e-98 326.9 5.7 3.5e-98 326.7 4.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hormone_recep PF00104.25 EMC83188.1 - 5.5e-33 113.8 1.2 7e-33 113.4 0.0 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC83188.1 - 6.6e-31 106.3 15.9 6.6e-31 106.3 11.0 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) zf-C4 PF00105.13 EMC83189.1 - 2.5e-30 104.5 15.9 5.3e-30 103.4 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC83189.1 - 1.4e-21 76.5 0.0 2.7e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC83190.1 - 3.4e-34 116.8 16.3 4e-34 116.6 11.3 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC83191.1 - 1.5e-18 66.7 0.0 1.6e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DNA_topoisoIV PF00521.15 EMC83192.1 - 8.2e-132 440.0 0.2 1.5e-131 439.1 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DTHCT PF08070.6 EMC83192.1 - 8.8e-32 109.6 15.7 8.8e-32 109.6 10.9 5.9 3 1 3 6 6 6 1 DTHCT (NUC029) region DNA_gyraseB PF00204.20 EMC83192.1 - 4.7e-31 107.3 1.2 1.4e-30 105.7 0.8 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EMC83192.1 - 6.9e-15 54.8 0.1 3.8e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EMC83192.1 - 8.9e-10 38.2 0.0 2.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PUB PF09409.5 EMC83193.1 - 1.4e-15 56.8 0.1 3.2e-14 52.4 0.0 2.8 2 0 0 2 2 2 1 PUB domain Transglut_core PF01841.14 EMC83193.1 - 1.1e-13 51.3 2.1 1.7e-13 50.7 0.7 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.10 EMC83193.1 - 3.1e-11 42.8 1.0 5.7e-11 42.0 0.7 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain DUF750 PF04721.12 EMC83193.1 - 7.5e-07 29.0 1.0 1.7e-06 27.9 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF750) Terminase_1 PF03354.10 EMC83193.1 - 0.013 13.9 0.0 0.75 8.1 0.1 2.1 2 0 0 2 2 2 0 Phage Terminase ketoacyl-synt PF00109.21 EMC83194.1 - 3.1e-54 184.1 2.3 3.1e-54 184.1 1.6 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMC83194.1 - 3.1e-36 123.8 0.2 3.1e-36 123.8 0.2 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMC83194.1 - 2.3e-05 23.5 0.1 6.6e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain LRR_8 PF13855.1 EMC83195.1 - 3.3e-16 58.7 5.5 5.9e-11 41.9 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EMC83195.1 - 4e-11 41.3 6.9 0.0034 17.2 0.2 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.2 EMC83195.1 - 1.5e-09 37.2 10.6 5.6e-07 29.0 0.3 3.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRRNT PF01462.13 EMC83195.1 - 6.6e-09 35.0 2.8 6.6e-09 35.0 2.0 2.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 EMC83195.1 - 2.9e-06 27.0 0.1 4.6e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC83195.1 - 1.1e-05 24.8 3.9 2.3 8.7 0.0 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EMC83195.1 - 1.4e-05 24.6 1.4 0.59 10.3 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich repeat HCO3_cotransp PF00955.16 EMC83196.1 - 2.6e-245 814.9 11.8 3.3e-245 814.5 8.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 EMC83196.1 - 2.3e-103 345.1 0.0 2.4e-102 341.8 0.0 2.3 1 1 0 1 1 1 1 Band 3 cytoplasmic domain TALPID3 PF15324.1 EMC83196.1 - 0.48 7.7 6.5 0.8 6.9 4.5 1.2 1 0 0 1 1 1 0 Hedgehog signalling target T-box PF00907.17 EMC83197.1 - 8.4e-80 266.5 0.7 1.1e-79 266.1 0.5 1.2 1 0 0 1 1 1 1 T-box Cmc1 PF08583.5 EMC83198.1 - 1.5e-17 63.0 5.6 2e-17 62.7 3.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Tmemb_18A PF09771.4 EMC83198.1 - 0.017 15.1 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 Colipase PF01114.13 EMC83198.1 - 0.019 14.4 1.7 0.03 13.7 1.2 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain Ribosom_S12_S23 PF00164.20 EMC83198.1 - 0.051 13.0 0.1 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S12/S23 CHCH PF06747.8 EMC83198.1 - 0.65 9.9 8.7 3.5 7.6 0.1 2.6 3 0 0 3 3 3 0 CHCH domain NDUF_B7 PF05676.8 EMC83198.1 - 2.3 7.6 6.7 0.45 9.9 1.4 1.9 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ecTbetaR2 PF08917.5 EMC83199.1 - 8.5e-52 173.8 16.2 8.5e-52 173.8 11.3 2.0 2 0 0 2 2 2 1 Transforming growth factor beta receptor 2 ectodomain Pkinase PF00069.20 EMC83199.1 - 2.4e-49 167.8 0.0 4.7e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83199.1 - 1.4e-35 122.6 0.0 2.4e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.1 EMC83199.1 - 0.019 14.6 0.2 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 EMC83199.1 - 0.049 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) APH PF01636.18 EMC83199.1 - 0.057 13.1 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C_tripleX PF02363.14 EMC83200.1 - 0.63 10.2 33.9 16 5.7 5.1 3.3 1 1 1 2 2 2 0 Cysteine rich repeat MAM PF00629.18 EMC83201.1 - 1.3e-52 177.7 0.0 2.6e-52 176.8 0.0 1.5 1 0 0 1 1 1 1 MAM domain I-set PF07679.11 EMC83201.1 - 1.8e-37 127.0 0.0 9.9e-12 44.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83201.1 - 2e-31 107.9 0.3 3.5e-10 39.8 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 EMC83201.1 - 9.4e-27 93.3 0.6 7.6e-08 32.7 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC83201.1 - 2.2e-19 69.4 3.5 5e-05 23.1 0.0 6.2 4 3 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.20 EMC83201.1 - 6.4e-19 67.8 6.1 1.4e-06 28.2 0.0 4.7 5 1 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.7 EMC83201.1 - 7.8e-08 32.1 0.2 0.0075 16.1 0.0 3.5 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Marek_A PF02124.10 EMC83201.1 - 0.061 12.7 0.0 0.34 10.3 0.0 2.1 2 1 1 3 3 3 0 Marek's disease glycoprotein A C1-set PF07654.10 EMC83201.1 - 0.07 13.1 1.2 0.27 11.2 0.0 2.7 4 0 0 4 4 4 0 Immunoglobulin C1-set domain BiPBP_C PF06832.7 EMC83201.1 - 0.092 12.6 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Helicase_C PF00271.26 EMC83202.1 - 2e-14 53.2 0.1 3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMC83202.1 - 0.024 13.4 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 zf-C2H2_4 PF13894.1 EMC83203.1 - 2.4e-09 36.8 19.1 0.00025 21.1 0.4 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC83203.1 - 3.2e-09 36.3 13.6 5.7e-09 35.5 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC83203.1 - 0.00032 20.8 20.8 0.0085 16.3 0.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMC83203.1 - 0.0011 19.0 12.9 0.049 13.7 3.1 3.2 2 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC83203.1 - 0.014 15.5 6.2 13 6.1 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Vps39_2 PF10367.4 EMC83203.1 - 0.11 12.6 6.4 0.051 13.7 2.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF629 PF04780.7 EMC83203.1 - 0.27 9.7 6.6 3 6.2 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.3 EMC83203.1 - 0.49 10.6 15.1 0.12 12.5 1.6 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EMC83203.1 - 5.3 6.7 10.4 0.64 9.6 0.1 3.1 3 0 0 3 3 3 0 GAGA factor ANF_receptor PF01094.23 EMC83204.1 - 5.1e-17 61.6 0.0 5.8e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Collagen PF01391.13 EMC83205.1 - 0.24 10.9 6.1 1.3 8.6 0.8 2.2 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Homeobox_KN PF05920.6 EMC83207.1 - 2.2e-19 68.8 1.6 4.5e-19 67.8 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC83207.1 - 3.9e-08 32.7 0.5 9e-08 31.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain dDENN PF03455.14 EMC83207.1 - 0.028 14.4 0.1 0.72 9.9 0.0 2.4 2 0 0 2 2 2 0 dDENN domain RNA_pol_3_Rpc31 PF11705.3 EMC83207.1 - 0.037 13.9 8.7 0.067 13.1 6.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.13 EMC83207.1 - 0.068 12.3 5.9 0.17 11.0 4.1 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Nro1 PF12753.2 EMC83207.1 - 0.19 10.6 7.7 0.35 9.7 5.3 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 BSP_II PF05432.6 EMC83207.1 - 0.19 10.9 11.1 0.37 10.0 7.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Med4 PF10018.4 EMC83207.1 - 0.29 10.5 11.7 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 NOA36 PF06524.7 EMC83207.1 - 0.39 9.9 5.1 0.056 12.6 0.9 1.5 2 0 0 2 2 2 0 NOA36 protein Prothymosin PF03247.9 EMC83207.1 - 0.71 10.0 22.1 1.5 9.0 15.3 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family TFIIA PF03153.8 EMC83207.1 - 0.77 9.5 11.0 0.067 13.0 4.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 EMC83207.1 - 1 8.4 14.0 1.6 7.7 9.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EMC83207.1 - 2.2 6.1 11.3 3 5.6 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EMC83207.1 - 2.3 7.1 10.2 3.9 6.3 7.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EMC83207.1 - 2.9 6.2 13.6 4.2 5.7 9.4 1.2 1 0 0 1 1 1 0 Daxx Family DUF1053 PF06327.9 EMC83207.1 - 9 6.7 10.3 2.7 8.3 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) MFS_1 PF07690.11 EMC83208.1 - 3.9e-40 137.6 31.3 5.7e-35 120.6 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EMC83208.1 - 0.0002 19.6 1.7 0.037 12.0 0.2 2.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF3664 PF12406.3 EMC83208.1 - 1.2 9.7 3.3 1.9 9.1 2.3 1.2 1 0 0 1 1 1 0 Surface protein I-set PF07679.11 EMC83209.1 - 4.7e-14 52.0 0.0 5.4e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83209.1 - 4.1e-12 46.4 0.1 5.3e-10 39.6 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 EMC83209.1 - 1.5e-11 44.1 0.0 1.4e-06 28.2 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC83209.1 - 6.6e-11 42.1 0.0 2.4e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC83209.1 - 7.7e-08 32.3 0.0 1.9e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC83209.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF1191 PF06697.7 EMC83209.1 - 0.046 12.5 0.0 0.067 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EMC83209.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ig_2 PF13895.1 EMC83211.1 - 2.5e-12 46.7 0.2 3e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC83211.1 - 1.2e-11 44.5 0.0 4e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC83211.1 - 1.8e-11 43.7 0.0 6.7e-07 29.0 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83211.1 - 1.3e-09 38.3 0.4 1e-07 32.3 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 EMC83211.1 - 5.6e-08 32.6 0.1 0.002 17.9 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 EMC83211.1 - 0.001 17.4 0.1 0.014 13.7 0.0 2.0 1 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 EMC83211.1 - 0.0035 17.2 0.3 0.024 14.5 0.1 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Herpes_gI PF01688.12 EMC83211.1 - 0.069 12.2 0.1 1.1 8.3 0.0 2.4 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein I REJ PF02010.10 EMC83211.1 - 0.11 10.7 0.1 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 REJ domain RIIa PF02197.12 EMC83212.1 - 1.4e-13 50.0 0.2 1.5e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PseudoU_synth_1 PF01416.15 EMC83213.1 - 7.5e-34 116.3 0.0 1.8e-20 73.3 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF1192 PF06698.6 EMC83213.1 - 0.024 14.4 0.4 0.046 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Shugoshin_N PF07558.6 EMC83213.1 - 0.084 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 EMC83213.1 - 0.12 12.2 2.9 0.23 11.2 2.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Lzipper-MIP1 PF14389.1 EMC83213.1 - 0.16 12.1 2.4 0.38 10.8 1.7 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 HYLS1_C PF15311.1 EMC83214.1 - 8.7e-30 102.8 5.4 1.4e-29 102.1 3.8 1.3 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus DEAD PF00270.24 EMC83215.1 - 1.4e-30 106.0 0.3 5.3e-28 97.6 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC83215.1 - 3e-24 84.6 0.7 6.9e-24 83.5 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EMC83215.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_19 PF13245.1 EMC83215.1 - 0.05 13.3 0.5 0.2 11.4 0.1 2.3 2 1 0 2 2 2 0 Part of AAA domain P22_AR_N PF10547.4 EMC83217.1 - 0.068 12.9 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 P22_AR N-terminal domain RMF PF04957.7 EMC83218.1 - 0.83 9.3 6.0 0.49 10.1 0.5 2.4 2 0 0 2 2 2 0 Ribosome modulation factor Ribosomal_L4 PF00573.17 EMC83218.1 - 0.87 8.9 4.4 1.1 8.6 3.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family EI24 PF07264.6 EMC83219.1 - 1.6e-46 158.4 14.2 2.3e-46 157.9 9.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TRAM_LAG1_CLN8 PF03798.11 EMC83220.1 - 9.7e-19 67.6 8.7 2.3e-18 66.4 5.8 1.7 1 1 1 2 2 2 1 TLC domain ANF_receptor PF01094.23 EMC83221.1 - 0.0065 15.2 0.0 0.0082 14.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.23 EMC83222.1 - 6.3e-59 199.5 0.0 9.3e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 EMC83222.1 - 6e-47 159.0 0.1 9.9e-47 158.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 EMC83222.1 - 1.6e-26 92.0 0.1 3.8e-26 90.8 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC83222.1 - 5e-22 78.2 0.0 9.8e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 EMC83222.1 - 0.0065 15.8 0.0 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein LRR_4 PF12799.2 EMC83223.1 - 6.5e-12 44.7 22.7 7.9e-06 25.3 1.0 5.2 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC83223.1 - 7e-11 41.7 16.2 0.00034 20.3 0.1 4.0 3 1 1 4 4 4 3 Leucine rich repeat Ubiquitin_2 PF14560.1 EMC83223.1 - 1.9e-07 31.2 0.1 8.3e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain LRR_9 PF14580.1 EMC83223.1 - 1.1e-05 25.0 3.1 0.00094 18.7 0.1 3.0 1 1 2 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.1 EMC83223.1 - 0.00015 21.4 14.8 2.9 8.2 0.1 6.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 EMC83223.1 - 0.0019 17.9 17.3 1.7 8.9 0.2 6.2 7 0 0 7 7 7 3 Leucine Rich Repeat UN_NPL4 PF11543.3 EMC83223.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 LRR_7 PF13504.1 EMC83223.1 - 0.013 15.5 16.9 4.2 8.0 0.2 6.8 7 0 0 7 7 7 0 Leucine rich repeat ubiquitin PF00240.18 EMC83223.1 - 0.018 14.4 0.2 0.12 11.7 0.1 2.3 1 1 0 1 1 1 0 Ubiquitin family APG12 PF04110.8 EMC83223.1 - 0.071 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 FA_hydroxylase PF04116.8 EMC83224.1 - 1.9e-12 47.6 27.0 2.1e-12 47.4 15.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SNARE_assoc PF09335.6 EMC83224.1 - 0.06 13.5 1.9 5.6 7.1 0.1 2.3 2 0 0 2 2 2 0 SNARE associated Golgi protein Ldl_recept_a PF00057.13 EMC83225.1 - 6.9e-82 269.0 162.1 2.7e-12 46.3 9.6 9.3 8 1 1 9 9 9 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 EMC83225.1 - 3.3e-26 91.3 6.1 1.1e-08 35.2 0.1 5.6 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B BNR PF02012.15 EMC83225.1 - 2.8e-05 23.3 13.3 1.3 9.1 0.2 5.6 5 0 0 5 5 5 4 BNR/Asp-box repeat fn3 PF00041.16 EMC83226.1 - 5.6e-07 29.5 1.0 0.00031 20.8 0.2 2.2 2 0 0 2 2 2 2 Fibronectin type III domain DUF4625 PF15418.1 EMC83226.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) fn3 PF00041.16 EMC83227.1 - 3e-12 46.4 0.1 6.6e-07 29.3 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain DUF3377 PF11857.3 EMC83227.1 - 0.0032 17.0 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Interfer-bind PF09294.5 EMC83227.1 - 0.0052 16.7 0.2 2.7 8.0 0.0 2.3 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III DUF4448 PF14610.1 EMC83227.1 - 0.0074 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 EMC83227.1 - 0.038 13.6 0.0 0.068 12.8 0.0 1.4 1 1 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 EMC83227.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.5 EMC83227.1 - 0.08 12.2 0.2 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1410 PF07198.6 EMC83227.1 - 0.26 11.6 2.1 14 6.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) His_Phos_1 PF00300.17 EMC83229.1 - 1.5e-23 83.6 0.0 3.8e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.1 EMC83229.1 - 4.6e-17 61.3 0.1 1.4e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain 2_5_RNA_ligase2 PF13563.1 EMC83229.1 - 4.3e-06 26.5 0.5 1e-05 25.3 0.2 1.7 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily SH3_1 PF00018.23 EMC83229.1 - 3.9e-05 22.9 0.0 8.2e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LigT_PEase PF02834.11 EMC83229.1 - 4.8e-05 23.2 0.1 0.26 11.2 0.1 2.7 3 0 0 3 3 3 2 LigT like Phosphoesterase His_Phos_2 PF00328.17 EMC83229.1 - 0.029 13.7 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) I-set PF07679.11 EMC83230.1 - 5.7e-11 42.1 0.0 0.00018 21.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83230.1 - 2.6e-09 37.0 0.4 3.7e-05 23.7 0.0 2.8 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC83230.1 - 3.1e-07 30.2 3.3 3.7e-07 29.9 0.1 2.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC83230.1 - 6.7e-07 29.2 3.2 1.4e-06 28.1 0.1 2.8 3 1 0 3 3 3 1 Immunoglobulin V-set domain C1-set PF07654.10 EMC83230.1 - 1.3e-05 25.1 1.8 1.6e-05 24.8 0.0 2.1 2 0 0 2 2 1 1 Immunoglobulin C1-set domain ig PF00047.20 EMC83230.1 - 0.0011 19.1 4.2 0.2 11.7 0.1 3.8 3 1 0 3 3 3 2 Immunoglobulin domain UPF0104 PF03706.8 EMC83230.1 - 0.014 14.6 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) TMEM154 PF15102.1 EMC83230.1 - 0.15 11.8 8.0 0.86 9.3 5.6 2.3 1 1 0 1 1 1 0 TMEM154 protein family TMEM51 PF15345.1 EMC83230.1 - 0.22 11.1 7.6 0.37 10.4 0.0 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 Ig_3 PF13927.1 EMC83230.1 - 1.8 9.1 8.6 6.1 7.4 0.2 3.7 3 2 0 3 3 3 0 Immunoglobulin domain ODV-E18 PF10717.4 EMC83230.1 - 7.8 6.0 6.4 2.4 7.6 1.8 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 UL73_N PF12522.3 EMC83230.1 - 7.9 6.1 8.9 7.3 6.2 0.7 2.7 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Homeobox PF00046.24 EMC83231.1 - 9.8e-11 41.1 6.9 3.2e-05 23.4 0.1 2.3 1 1 1 2 2 2 2 Homeobox domain Innate_immun PF12782.2 EMC83231.1 - 3.1 6.9 8.0 4.1 6.5 5.5 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family HSP70 PF00012.15 EMC83232.1 - 9.8e-241 799.8 11.0 1.1e-240 799.6 7.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC83232.1 - 1.7e-17 63.0 0.1 2.7e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 EMC83232.1 - 0.0011 18.5 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EMC83232.1 - 0.005 15.7 0.4 0.04 12.7 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EMC83232.1 - 0.02 14.0 0.3 0.39 9.7 0.1 2.4 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase SMN PF06003.7 EMC83234.1 - 0.0022 17.1 0.9 0.0025 16.9 0.7 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TMEM51 PF15345.1 EMC83234.1 - 0.0024 17.5 2.7 0.0037 16.9 1.9 1.4 1 1 0 1 1 1 1 Transmembrane protein 51 FAM176 PF14851.1 EMC83234.1 - 0.0029 17.2 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 FAM176 family Glycophorin_A PF01102.13 EMC83234.1 - 0.0057 16.4 2.2 0.69 9.6 0.0 2.1 2 0 0 2 2 2 1 Glycophorin A SR-25 PF10500.4 EMC83234.1 - 0.013 14.9 10.9 0.016 14.6 7.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM163 PF15069.1 EMC83234.1 - 0.014 16.0 0.0 0.016 15.8 0.0 1.1 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.1 EMC83234.1 - 0.029 14.7 0.3 0.089 13.1 0.0 1.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EMC83234.1 - 0.073 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Pex16 PF08610.5 EMC83234.1 - 0.073 12.0 0.5 0.085 11.8 0.3 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Trp_oprn_chp PF09534.5 EMC83234.1 - 0.12 11.9 0.2 0.21 11.1 0.1 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2217 PF10265.4 EMC83234.1 - 0.14 10.8 0.9 0.16 10.7 0.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PDE6_gamma PF04868.7 EMC83234.1 - 0.46 10.3 1.7 0.61 9.9 0.8 1.4 1 1 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit DUF2051 PF09738.4 EMC83234.1 - 0.59 9.3 5.7 0.68 9.1 3.9 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Sox_N PF12444.3 EMC83234.1 - 1.1 10.4 6.1 28 5.8 4.2 2.1 2 0 0 2 2 2 0 Sox developmental protein N terminal DUF2215 PF10225.4 EMC83234.1 - 2.5 7.4 5.3 4.8 6.5 3.7 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) V-set PF07686.12 EMC83235.1 - 1.5e-07 31.2 0.0 1.7e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC83235.1 - 1.7e-07 30.9 0.0 2.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC83235.1 - 0.022 14.8 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.1 EMC83235.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain GRAM PF02893.15 EMC83236.1 - 1.4e-19 69.3 0.1 2.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain V-set PF07686.12 EMC83237.1 - 2e-17 63.1 0.1 2.9e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC83237.1 - 3.2e-07 30.3 0.2 6.1e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC83237.1 - 0.00011 21.9 0.3 0.00031 20.5 0.2 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83237.1 - 0.0013 19.1 1.3 0.016 15.6 0.9 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC83237.1 - 0.0025 17.8 0.5 0.0073 16.4 0.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain EII-GUT PF03608.8 EMC83237.1 - 0.0084 15.9 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 1 PTS system enzyme II sorbitol-specific factor OAD_gamma PF04277.8 EMC83237.1 - 0.039 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF843 PF05814.6 EMC83237.1 - 0.051 13.3 1.3 0.089 12.6 0.6 1.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) EBP PF05241.7 EMC83237.1 - 0.46 9.4 5.6 5.8 5.8 1.0 2.2 2 0 0 2 2 2 0 Emopamil binding protein E1-E2_ATPase PF00122.15 EMC83238.1 - 7e-61 205.1 4.4 1.5e-60 204.0 3.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC83238.1 - 8.2e-42 142.7 1.4 8.2e-42 142.7 1.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC83238.1 - 3.4e-30 106.0 0.0 8.6e-30 104.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC83238.1 - 1.8e-26 91.9 0.0 4.8e-26 90.5 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMC83238.1 - 1.6e-16 59.5 0.0 3.4e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC83238.1 - 1.9e-16 60.7 0.0 5.5e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC83238.1 - 7.5e-05 22.4 9.5 0.00044 19.9 0.8 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.11 EMC83238.1 - 0.015 14.5 0.1 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Cytidylate_kin2 PF13189.1 EMC83238.1 - 0.067 13.0 0.8 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family Asp_protease PF09668.5 EMC83238.1 - 0.074 12.6 0.5 22 4.6 0.0 3.0 3 0 0 3 3 3 0 Aspartyl protease PKD PF00801.15 EMC83239.1 - 0.14 11.8 0.2 0.29 10.8 0.1 1.5 2 0 0 2 2 2 0 PKD domain Glyco_transf_43 PF03360.11 EMC83240.1 - 2.8e-38 131.5 0.0 3.2e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Acyl-CoA_dh_1 PF00441.19 EMC83241.1 - 3e-46 157.2 4.8 4.3e-46 156.7 3.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC83241.1 - 9.6e-29 100.2 0.1 2.6e-28 98.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC83241.1 - 3.3e-23 82.4 2.0 5.1e-23 81.8 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC83241.1 - 1.3e-20 72.6 0.2 3.3e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain EVE PF01878.13 EMC83242.1 - 1.8e-51 173.9 0.1 1.8e-51 173.9 0.0 1.4 2 0 0 2 2 2 1 EVE domain Vps26 PF03643.10 EMC83243.1 - 3.3e-131 436.1 6.2 3.9e-131 435.8 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EMC83243.1 - 4e-05 23.4 2.2 0.0077 16.0 0.1 3.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Cnd1 PF12717.2 EMC83244.1 - 6.5e-66 221.5 22.7 4.1e-58 196.1 2.6 6.9 3 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMC83244.1 - 2.4e-14 52.0 9.1 0.29 11.3 0.1 8.5 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.15 EMC83244.1 - 4e-10 38.6 16.4 7.3e-05 21.2 4.6 4.5 4 2 1 5 5 5 3 Adaptin N terminal region HEAT_2 PF13646.1 EMC83244.1 - 4e-10 39.8 4.9 0.0039 17.4 0.2 6.0 5 2 0 5 5 5 2 HEAT repeats Cohesin_HEAT PF12765.2 EMC83244.1 - 3e-08 33.4 3.1 0.0062 16.4 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 EMC83244.1 - 0.0049 16.7 3.5 2.2 8.2 0.1 5.0 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) DUF4359 PF14271.1 EMC83244.1 - 0.58 10.5 4.2 6.8 7.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4359) HEAT_EZ PF13513.1 EMC83244.1 - 3 8.4 11.6 47 4.6 0.0 6.6 6 2 2 8 8 8 0 HEAT-like repeat I-set PF07679.11 EMC83245.1 - 1.5e-20 72.8 0.5 7.9e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 EMC83245.1 - 7.7e-18 64.4 2.6 2.8e-09 36.8 0.1 2.3 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC83245.1 - 1.4e-16 60.3 2.2 7.8e-09 35.5 0.3 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC83245.1 - 2.4e-11 43.6 6.1 0.00013 21.9 0.3 3.7 2 2 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC83245.1 - 6.7e-09 36.1 7.4 1.9e-06 28.2 1.5 3.1 2 2 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.10 EMC83245.1 - 1e-06 28.6 0.5 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC83245.1 - 0.0002 21.1 0.4 0.019 14.8 0.1 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.1 EMC83245.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EMC83245.1 - 0.14 11.6 4.6 0.27 10.8 3.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 I-set PF07679.11 EMC83246.1 - 8.9e-54 179.3 0.0 6.5e-15 54.7 0.0 5.7 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83246.1 - 7.3e-42 141.3 0.0 3.3e-11 43.1 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 EMC83246.1 - 1.7e-31 108.4 2.7 6.4e-09 36.1 0.0 6.6 6 1 0 6 6 6 5 Immunoglobulin domain ig PF00047.20 EMC83246.1 - 5e-28 97.0 0.0 5.2e-10 39.3 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 EMC83246.1 - 6.1e-24 84.1 0.0 1.6e-07 31.1 0.0 6.3 5 1 0 5 5 5 3 Immunoglobulin V-set domain fn3 PF00041.16 EMC83246.1 - 2.2e-14 53.3 0.0 9.9e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain C2-set_2 PF08205.7 EMC83246.1 - 0.0001 22.1 1.8 0.05 13.5 0.0 4.5 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 EMC83246.1 - 0.0019 17.9 0.1 0.13 11.9 0.1 2.7 3 0 0 3 3 3 1 Tissue factor Herpes_gE PF02480.11 EMC83246.1 - 0.0036 15.6 0.0 17 3.5 0.0 4.0 3 2 0 4 4 4 0 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 EMC83246.1 - 0.073 12.8 0.0 17 5.1 0.0 3.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain Ldr_toxin PF13940.1 EMC83246.1 - 0.21 11.3 3.1 6.1 6.7 0.3 3.2 2 1 1 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system I-set PF07679.11 EMC83247.1 - 1e-36 124.6 2.8 4.8e-15 55.1 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83247.1 - 1.9e-28 98.3 1.3 3.6e-11 43.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC83247.1 - 2e-24 85.8 4.3 5.9e-11 42.7 0.0 3.3 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC83247.1 - 1.1e-21 76.6 1.5 4.1e-10 39.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC83247.1 - 1.6e-15 56.9 6.9 0.00011 22.1 0.3 4.7 3 2 0 3 3 3 3 Immunoglobulin V-set domain V-set_CD47 PF08204.6 EMC83247.1 - 0.00012 21.8 1.0 0.29 10.9 0.1 3.1 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set_2 PF08205.7 EMC83247.1 - 0.0012 18.6 0.1 0.43 10.5 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC83247.1 - 0.004 15.5 0.7 0.031 12.5 0.2 2.3 1 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E I-set PF07679.11 EMC83248.1 - 5.6e-35 119.0 0.2 2e-13 49.9 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83248.1 - 8.7e-29 99.4 0.2 3.5e-12 46.2 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC83248.1 - 8.6e-25 87.0 2.0 4.2e-11 43.1 0.1 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 EMC83248.1 - 5.8e-23 80.7 1.5 6.2e-12 45.4 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC83248.1 - 1.7e-16 60.1 2.4 0.00018 21.3 0.1 4.7 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC83248.1 - 3.6e-06 26.7 0.2 0.031 14.1 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 EMC83248.1 - 0.0011 18.7 0.1 0.55 9.9 0.0 3.0 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 EMC83248.1 - 0.0031 15.8 0.3 0.19 9.9 0.0 2.7 2 1 0 3 3 3 1 Alphaherpesvirus glycoprotein E Phage_XkdX PF09693.5 EMC83248.1 - 0.14 11.7 0.3 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) DUF1151 PF06625.6 EMC83249.1 - 5.5e-52 174.6 21.2 6.3e-52 174.4 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) HTH_43 PF09904.4 EMC83249.1 - 0.095 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix MRP-S26 PF14943.1 EMC83249.1 - 0.098 12.2 13.2 0.11 12.0 9.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4045 PF13254.1 EMC83249.1 - 2.9 7.0 11.4 2.4 7.3 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4045) HSP70 PF00012.15 EMC83250.1 - 5.4e-107 358.1 0.1 6.1e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC83250.1 - 3.2e-11 42.4 0.0 5.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein B5 PF03484.10 EMC83250.1 - 0.026 14.3 0.1 0.94 9.3 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetase B5 domain SET PF00856.23 EMC83251.1 - 1e-27 97.3 0.2 4.1e-27 95.4 0.1 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EMC83251.1 - 2.1e-22 79.2 3.4 2.1e-22 79.2 2.3 2.4 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 EMC83251.1 - 2e-14 52.9 1.8 4.4e-14 51.8 1.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DRMBL PF07522.9 EMC83252.1 - 1e-17 64.1 0.0 2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EMC83252.1 - 3.2e-05 23.5 0.0 8.9e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC83252.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily BTV_NS2 PF04514.7 EMC83252.1 - 3.6 6.3 9.8 4.6 6.0 5.8 1.9 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Meiosis_expr PF15163.1 EMC83253.1 - 2.7e-37 126.9 10.3 3.1e-37 126.7 7.1 1.0 1 0 0 1 1 1 1 Meiosis-expressed RRP7 PF12923.2 EMC83253.1 - 0.024 14.6 0.1 0.024 14.6 0.1 1.8 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DUF2678 PF10856.3 EMC83254.1 - 1.7e-47 159.9 6.1 1.8e-47 159.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Polysacc_synt_C PF14667.1 EMC83254.1 - 4.2e-05 23.3 1.9 5.3e-05 23.0 1.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain ABC2_membrane_3 PF12698.2 EMC83254.1 - 0.11 11.5 4.5 0.13 11.2 3.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_M50 PF02163.17 EMC83254.1 - 0.13 11.1 3.2 3.2 6.6 2.1 2.0 1 1 0 1 1 1 0 Peptidase family M50 7TMR-DISM_7TM PF07695.6 EMC83254.1 - 1.5 8.4 12.6 11 5.6 8.9 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF2417 PF10329.4 EMC83254.1 - 2.8 7.3 6.5 3.9 6.8 4.5 1.3 1 1 0 1 1 1 0 Region of unknown function (DUF2417) YesK PF14150.1 EMC83254.1 - 3.9 7.6 9.8 0.21 11.6 1.7 2.0 1 1 1 2 2 2 0 YesK-like protein DUF4131 PF13567.1 EMC83254.1 - 6.6 6.0 8.8 0.59 9.5 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Myb_DNA-binding PF00249.26 EMC83255.1 - 1e-22 79.9 7.7 6.4e-14 51.7 0.3 4.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC83255.1 - 9.4e-21 73.6 8.8 1.7e-13 50.4 0.1 4.2 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EMC83255.1 - 0.032 14.3 0.5 0.032 14.3 0.3 3.6 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain TLV_coat PF00429.14 EMC83256.1 - 1.6e-08 33.4 0.8 1.9e-08 33.2 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GCC2_GCC3 PF07699.8 EMC83257.1 - 2.5e-12 46.1 75.0 1.3e-05 24.6 4.3 8.7 5 3 3 8 8 8 7 GCC2 and GCC3 ANF_receptor PF01094.23 EMC83258.1 - 1.4e-93 313.5 0.2 1.7e-93 313.1 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 EMC83258.1 - 2.7e-79 265.8 23.0 4.6e-79 265.1 15.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 EMC83258.1 - 1.7e-15 56.4 10.8 4.3e-15 55.1 7.5 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 EMC83258.1 - 3.7e-09 36.3 0.1 7.6e-09 35.3 0.0 1.6 2 1 0 2 2 2 1 Periplasmic binding protein Sema PF01403.14 EMC83259.1 - 7e-171 568.5 0.0 3.1e-170 566.3 0.0 1.8 1 1 1 2 2 2 2 Sema domain V-set PF07686.12 EMC83259.1 - 4.7e-05 23.2 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.20 EMC83259.1 - 0.00016 21.7 9.6 0.00038 20.5 6.7 1.6 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.11 EMC83259.1 - 0.00081 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83259.1 - 0.0011 19.0 0.1 0.0068 16.5 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 EMC83259.1 - 0.037 14.5 0.0 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain WD40 PF00400.27 EMC83259.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Sema PF01403.14 EMC83260.1 - 9.1e-176 584.6 0.0 1.7e-175 583.6 0.0 1.4 2 0 0 2 2 2 1 Sema domain V-set PF07686.12 EMC83260.1 - 5e-06 26.3 0.0 1.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.20 EMC83260.1 - 0.00015 21.8 6.9 0.00015 21.8 4.8 2.1 2 0 0 2 2 2 1 Plexin repeat ig PF00047.20 EMC83260.1 - 0.00031 20.7 0.0 0.00094 19.2 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 EMC83260.1 - 0.0019 18.2 0.0 0.0057 16.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC83260.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83260.1 - 0.017 15.5 0.0 1.5 9.3 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin domain Sema PF01403.14 EMC83261.1 - 1.5e-168 560.8 0.0 2.2e-168 560.3 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 EMC83261.1 - 0.00044 20.3 6.6 0.00044 20.3 4.6 1.9 2 0 0 2 2 2 1 Plexin repeat V-set PF07686.12 EMC83261.1 - 0.00048 19.9 0.0 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC83261.1 - 0.011 15.8 0.0 0.043 13.9 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain VGCC_alpha2 PF08473.6 EMC83264.1 - 3.1e-48 161.4 0.9 6.2e-48 160.4 0.7 1.5 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.6 EMC83264.1 - 1.1e-41 142.2 1.4 2.8e-41 140.9 0.3 2.2 2 0 0 2 2 2 1 VWA N-terminal Cache_1 PF02743.13 EMC83264.1 - 1.2e-28 98.4 0.1 4.8e-28 96.5 0.0 2.1 3 0 0 3 3 3 1 Cache domain VWA PF00092.23 EMC83264.1 - 1.8e-20 73.4 0.4 3.6e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC83264.1 - 3.2e-13 49.6 0.0 5.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC83264.1 - 5.2e-13 49.4 0.0 1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EMC83264.1 - 0.0016 18.3 0.3 0.0039 17.0 0.2 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus Cache_2 PF08269.6 EMC83264.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Cache domain DUF2201 PF09967.4 EMC83264.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) VWA_CoxE PF05762.9 EMC83264.1 - 0.33 10.0 0.0 0.63 9.1 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Kringle PF00051.13 EMC83265.1 - 3.8e-110 360.1 41.1 2.4e-29 101.2 4.8 4.5 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.21 EMC83265.1 - 1.5e-47 161.9 0.6 2.4e-47 161.3 0.0 1.6 2 0 0 2 2 2 1 Trypsin PAN_1 PF00024.21 EMC83265.1 - 1.9e-10 40.3 1.1 5.6e-10 38.8 0.7 1.8 1 0 0 1 1 1 1 PAN domain DUF1986 PF09342.6 EMC83265.1 - 0.00062 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Sema PF01403.14 EMC83266.1 - 3.4e-168 559.6 0.0 4.8e-168 559.1 0.0 1.2 1 0 0 1 1 1 1 Sema domain I-set PF07679.11 EMC83266.1 - 5.5e-06 26.1 0.2 1.6e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.12 EMC83266.1 - 0.00047 20.0 0.3 0.0023 17.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain PSI PF01437.20 EMC83266.1 - 0.00087 19.3 8.4 0.00087 19.3 5.8 2.4 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.1 EMC83266.1 - 0.0016 18.5 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC83266.1 - 0.01 16.3 0.0 0.039 14.4 0.0 2.0 1 0 0 1 1 1 0 Immunoglobulin domain CD36 PF01130.16 EMC83267.1 - 4.3e-144 480.3 0.0 5e-144 480.1 0.0 1.0 1 0 0 1 1 1 1 CD36 family DUF3068 PF11271.3 EMC83267.1 - 0.16 11.0 0.0 0.37 9.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) G-alpha PF00503.15 EMC83268.1 - 2.5e-132 441.2 2.4 3e-132 440.9 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC83268.1 - 1.2e-15 57.2 0.9 1.6e-11 43.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF2951 PF11166.3 EMC83268.1 - 0.019 14.7 0.2 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Gtr1_RagA PF04670.7 EMC83268.1 - 0.029 13.5 4.4 1 8.4 0.4 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC83268.1 - 0.045 14.2 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EMC83268.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMC83268.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.15 EMC83269.1 - 1.6e-125 418.8 2.2 1.8e-125 418.6 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC83269.1 - 1.1e-13 50.8 0.5 2e-10 40.1 0.2 3.2 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EMC83269.1 - 0.0082 16.6 0.4 1.5 9.3 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein PDZ PF00595.19 EMC83270.1 - 6.2e-61 202.5 10.0 3.1e-15 56.0 0.0 5.5 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC83270.1 - 4e-30 103.5 0.2 2.9e-05 23.8 0.0 5.3 5 0 0 5 5 5 5 PDZ domain WW PF00397.21 EMC83270.1 - 7.6e-16 57.6 6.7 4.7e-09 35.9 0.2 3.1 3 0 0 3 3 3 2 WW domain Guanylate_kin PF00625.16 EMC83270.1 - 6.8e-09 35.4 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.1 EMC83270.1 - 6.8e-07 29.0 2.2 1.3 8.8 0.0 5.0 5 0 0 5 5 5 3 Tricorn protease PDZ domain YodL PF14191.1 EMC83270.1 - 0.072 13.5 0.0 0.27 11.7 0.0 2.0 1 0 0 1 1 1 0 YodL-like Phtf-FEM1B_bdg PF12129.3 EMC83271.1 - 5.9e-86 285.7 0.8 5.9e-86 285.7 0.6 2.1 2 0 0 2 2 2 1 Male germ-cell putative homeodomain transcription factor Tmemb_185A PF10269.4 EMC83272.1 - 4.1e-14 52.7 29.2 6.6e-10 39.0 7.4 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF3522 PF12036.3 EMC83272.1 - 0.082 12.6 5.4 0.13 12.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) CoA_binding_3 PF13727.1 EMC83272.1 - 1.1 9.0 14.3 0.069 12.9 3.7 2.0 1 1 1 2 2 2 0 CoA-binding domain DUF1275 PF06912.6 EMC83272.1 - 1.6 7.9 6.7 0.68 9.0 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) DUF1430 PF07242.6 EMC83272.1 - 5.4 7.1 9.3 8.5 6.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) TcpE PF12648.2 EMC83272.1 - 9.9 6.3 11.6 6.3 6.9 3.4 2.1 2 0 0 2 2 2 0 TcpE family Y_phosphatase PF00102.22 EMC83273.1 - 1.4e-82 276.5 0.2 2e-82 276.0 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC83273.1 - 0.0031 17.7 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EMC83273.1 - 0.0035 16.9 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC83273.1 - 0.013 15.6 0.9 0.071 13.1 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate GSAP-16 PF14959.1 EMC83274.1 - 1.9e-43 146.8 0.2 6.3e-43 145.1 0.0 2.0 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term Reo_sigmaC PF04582.7 EMC83275.1 - 8.7 5.4 28.5 0.41 9.7 0.4 6.1 3 2 1 7 7 7 0 Reovirus sigma C capsid protein p450 PF00067.17 EMC83276.1 - 2.5e-47 161.4 0.0 2.8e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RhoGAP PF00620.22 EMC83280.1 - 1.8e-07 30.8 0.1 2.3e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain IRK PF01007.15 EMC83282.1 - 5.2e-131 436.4 2.4 4.3e-97 324.9 0.0 2.0 1 1 1 2 2 2 2 Inward rectifier potassium channel DUF3938 PF13074.1 EMC83282.1 - 1.1 9.1 3.3 0.9 9.4 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Calsequestrin PF01216.12 EMC83284.1 - 9.7e-161 534.7 51.0 6.8e-156 518.8 4.6 2.9 1 1 1 2 2 2 2 Calsequestrin Thioredoxin_6 PF13848.1 EMC83284.1 - 1.5e-18 67.2 3.4 2.1e-15 57.0 1.1 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Nop14 PF04147.7 EMC83284.1 - 1.9 6.2 20.8 2.4 5.9 14.4 1.2 1 0 0 1 1 1 0 Nop14-like family DED PF01335.16 EMC83285.1 - 8.9e-18 64.1 0.0 1.2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Death effector domain FCD PF07729.7 EMC83285.1 - 0.013 15.7 0.1 0.027 14.7 0.1 1.5 1 1 0 1 1 1 0 FCD domain Pex19 PF04614.7 EMC83286.1 - 6.1e-10 39.1 0.0 6.9e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Pex19 protein family Complex1_49kDa PF00346.14 EMC83287.1 - 1.4e-41 142.2 0.0 1.6e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ca_chan_IQ PF08763.6 EMC83289.1 - 0.04 13.1 0.3 0.071 12.3 0.2 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain IQ PF00612.22 EMC83289.1 - 0.13 11.9 0.3 0.18 11.5 0.2 1.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ribosomal_60s PF00428.14 EMC83289.1 - 3.4 8.1 12.3 2.2 8.7 7.7 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein Myelin-PO_C PF10570.4 EMC83290.1 - 6.5e-40 135.0 7.4 9e-40 134.6 5.1 1.2 1 0 0 1 1 1 1 Myelin-PO cytoplasmic C-term p65 binding region V-set PF07686.12 EMC83290.1 - 4.1e-16 58.8 0.4 6e-16 58.3 0.3 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC83290.1 - 1e-06 28.7 0.1 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC83290.1 - 0.001 19.1 0.3 0.0021 18.1 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC83290.1 - 0.0019 17.9 0.1 0.0053 16.5 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Herpes_gE PF02480.11 EMC83290.1 - 0.002 16.4 1.9 0.18 10.0 1.5 2.1 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E Ig_3 PF13927.1 EMC83290.1 - 0.023 15.2 2.7 2 8.9 1.6 3.0 1 1 0 1 1 1 0 Immunoglobulin domain Sdh_cyt PF01127.17 EMC83291.1 - 4.7e-20 71.6 2.9 1e-18 67.2 0.6 2.2 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Trichoplein PF13868.1 EMC83292.1 - 3.8e-58 196.5 129.5 3.8e-58 196.5 89.8 2.1 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin CH PF00307.26 EMC83293.1 - 3.2e-08 33.5 0.0 4.7e-08 33.0 0.0 1.3 1 1 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EMC83293.1 - 0.081 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 CDC24 Calponin Pentaxin PF00354.12 EMC83294.1 - 1.7e-74 249.5 0.0 1.9e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 EMC83294.1 - 1.8e-10 41.2 0.0 2.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily S_100 PF01023.14 EMC83295.1 - 1.8e-20 71.9 0.4 3.9e-20 70.8 0.3 1.6 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_4 PF12763.2 EMC83295.1 - 1.2e-05 24.9 0.0 1.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EMC83295.1 - 0.00037 20.5 0.2 0.00052 20.0 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC83295.1 - 0.003 16.7 0.5 0.028 13.6 0.1 2.3 2 0 0 2 2 2 1 EF hand DUF3837 PF12939.2 EMC83295.1 - 0.12 12.3 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) M PF02370.11 EMC83295.1 - 0.46 10.9 1.9 0.75 10.3 0.0 2.1 2 0 0 2 2 2 0 M protein repeat EF-hand_7 PF13499.1 EMC83296.1 - 3.3e-08 33.5 0.2 5.8e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair S_100 PF01023.14 EMC83296.1 - 1.8e-06 27.1 0.0 3.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_5 PF13202.1 EMC83296.1 - 2.6e-06 26.5 0.8 0.00017 20.7 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 EMC83296.1 - 2.6e-06 26.3 0.8 0.00092 18.3 0.1 2.6 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC83296.1 - 0.00071 19.2 0.1 0.61 10.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC83296.1 - 0.0011 18.4 1.5 0.0062 16.1 0.7 2.2 2 1 0 2 2 2 1 EF-hand domain pair S_100 PF01023.14 EMC83297.1 - 9.8e-07 28.0 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain S_100 PF01023.14 EMC83298.1 - 3.7e-21 74.1 1.6 5.6e-21 73.5 1.1 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 EMC83298.1 - 3e-07 29.2 0.4 7.9e-06 24.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMC83298.1 - 2.7e-06 27.4 0.3 4.1e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC83298.1 - 1.2e-05 24.4 2.1 0.00044 19.4 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EMC83298.1 - 0.00025 20.6 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC83298.1 - 0.0092 15.5 0.7 0.034 13.7 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 EMC83298.1 - 0.059 13.1 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Feld-I_B PF09252.5 EMC83298.1 - 0.063 13.1 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 Allergen Fel d I-B chain FoP_duplication PF13865.1 EMC83299.1 - 3.3e-21 75.5 0.5 3.3e-21 75.5 0.3 3.2 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Sbi-IV PF11621.3 EMC83299.1 - 1 9.5 10.5 6.8 6.9 0.0 3.8 2 2 2 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI DZF PF07528.9 EMC83301.1 - 5.5e-96 320.7 0.0 7.1e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 DZF domain BPL_N PF09825.4 EMC83302.1 - 0.027 13.2 0.3 0.032 13.0 0.2 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal SYS1 PF09801.4 EMC83303.1 - 5.7e-06 26.3 18.4 7.9e-06 25.9 12.7 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network MBT PF02820.13 EMC83304.1 - 1.7e-96 316.2 4.6 2.8e-33 113.6 0.0 3.4 3 0 0 3 3 3 3 mbt repeat SAM_1 PF00536.25 EMC83304.1 - 7.3e-15 54.9 0.0 1.3e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC PF01530.13 EMC83304.1 - 2.3e-07 30.4 10.3 7.2e-07 28.8 7.2 1.9 1 0 0 1 1 1 1 Zinc finger, C2HC type SAM_2 PF07647.12 EMC83304.1 - 1.8e-06 27.6 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC83305.1 - 2.5e-11 43.5 0.3 1.4e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC83305.1 - 3.5e-09 36.3 0.2 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF2371 PF10177.4 EMC83306.1 - 8.8e-57 190.9 0.0 2.9e-56 189.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) RbcS PF12338.3 EMC83306.1 - 0.0012 18.5 0.3 0.0042 16.8 0.2 1.9 1 0 0 1 1 1 1 Ribulose-1,5-bisphosphate carboxylase small subunit She9_MDM33 PF05546.6 EMC83306.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 1 1 1 2 2 2 0 She9 / Mdm33 family 4_1_CTD PF05902.8 EMC83308.1 - 1.2e-54 183.2 10.6 1.2e-54 183.2 7.3 2.8 2 1 0 2 2 2 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 EMC83308.1 - 2.3e-27 94.4 1.9 1.1e-26 92.2 1.3 2.3 1 0 0 1 1 1 1 SAB domain FERM_C PF09380.5 EMC83308.1 - 1.2e-23 83.0 0.1 3.9e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 EMC83308.1 - 8.7e-23 80.1 0.5 6e-22 77.5 0.2 2.6 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 EMC83308.1 - 4.6e-20 72.0 0.2 4.6e-20 72.0 0.1 2.9 3 1 0 3 3 3 1 FERM central domain FA PF08736.6 EMC83308.1 - 3.9e-18 64.9 2.0 1.6e-17 63.0 1.4 2.2 1 0 0 1 1 1 1 FERM adjacent (FA) AKAP7_NLS PF10469.4 EMC83309.1 - 1.8e-47 161.7 0.5 2.7e-47 161.1 0.4 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain AKAP7_RIRII_bdg PF10470.4 EMC83309.1 - 3.1e-26 90.9 3.2 6.7e-26 89.8 2.2 1.6 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein 2_5_RNA_ligase2 PF13563.1 EMC83309.1 - 1.1e-06 28.4 0.1 2.3e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.7 EMC83309.1 - 1.1e-05 24.9 0.4 9e-05 21.8 0.3 2.0 1 1 0 1 1 1 1 Coronavirus NS2A protein LigT_PEase PF02834.11 EMC83309.1 - 0.0051 16.7 0.1 2.1 8.4 0.0 2.7 3 0 0 3 3 3 2 LigT like Phosphoesterase MutS_V PF00488.16 EMC83310.1 - 1.3e-58 198.1 0.0 2.2e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC83310.1 - 7.6e-29 100.9 0.4 1.3e-28 100.1 0.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EMC83310.1 - 6.1e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 EMC83310.1 - 0.044 13.6 0.1 0.17 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain Med23 PF11573.3 EMC83311.1 - 0 1913.4 10.6 0 1913.2 7.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Phosphodiest PF01663.17 EMC83312.1 - 1.8e-78 264.4 0.2 2.3e-78 264.0 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 EMC83312.1 - 1.5e-19 69.6 36.9 1.1e-09 38.0 11.1 2.8 2 0 0 2 2 2 2 Somatomedin B domain Endonuclease_NS PF01223.18 EMC83312.1 - 2.6e-13 50.0 0.2 4e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Metalloenzyme PF01676.13 EMC83312.1 - 2.5e-05 23.8 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EMC83312.1 - 0.0043 16.2 0.1 0.24 10.5 0.1 2.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMC83313.1 - 6.5e-80 269.1 0.0 8.7e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 EMC83313.1 - 4.2e-18 65.0 44.9 9e-10 38.3 11.3 3.3 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.18 EMC83313.1 - 5.3e-09 36.0 0.1 1e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.18 EMC83313.1 - 0.001 18.3 0.0 0.038 13.1 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EMC83313.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Cys_knot PF00007.17 EMC83314.1 - 1.2e-16 60.6 10.5 1.2e-16 60.6 7.2 3.1 3 1 0 3 3 3 1 Cystine-knot domain TSP_1 PF00090.14 EMC83314.1 - 8.4e-11 41.8 6.4 8.4e-11 41.8 4.4 2.8 2 0 0 2 2 2 1 Thrombospondin type 1 domain VWC PF00093.13 EMC83314.1 - 4.6e-10 39.4 9.9 4.6e-10 39.4 6.9 3.9 2 1 0 2 2 2 1 von Willebrand factor type C domain Cu2_monooxygen PF01082.15 EMC83315.1 - 2.4e-45 153.7 1.7 2.8e-45 153.5 0.2 1.8 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.10 EMC83315.1 - 6.1e-36 123.1 0.1 4.8e-35 120.2 0.0 2.3 3 0 0 3 3 3 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.12 EMC83315.1 - 1.4e-11 44.3 0.3 2.5e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 DOMON domain Syntaxin_2 PF14523.1 EMC83317.1 - 2.3e-26 91.7 9.6 2.3e-26 91.7 6.7 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EMC83317.1 - 6.3e-20 70.6 8.0 6.3e-20 70.6 5.5 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EMC83317.1 - 2.1e-08 34.2 1.9 2.1e-08 34.2 1.3 2.5 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EMC83317.1 - 0.0028 17.2 3.1 0.0028 17.2 2.1 2.5 2 1 0 2 2 2 1 Synaptobrevin Prominin PF05478.6 EMC83317.1 - 0.017 12.6 0.3 0.017 12.6 0.2 2.0 2 0 0 2 2 2 0 Prominin Sec5 PF15469.1 EMC83317.1 - 0.027 14.2 5.4 0.3 10.8 0.2 2.4 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF2976 PF11190.3 EMC83317.1 - 0.034 13.6 0.1 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF4191 PF13829.1 EMC83317.1 - 0.037 13.1 0.3 0.072 12.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Herpes_US9 PF06072.6 EMC83317.1 - 0.038 13.8 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Peptidase_M61 PF05299.7 EMC83317.1 - 0.077 12.9 1.1 13 5.7 0.0 2.7 2 1 1 3 3 3 0 M61 glycyl aminopeptidase Reo_sigmaC PF04582.7 EMC83317.1 - 0.084 12.0 0.9 5 6.2 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein EAP30 PF04157.11 EMC83317.1 - 0.093 11.8 4.2 0.073 12.2 1.3 2.2 1 1 0 1 1 1 0 EAP30/Vps36 family Imm21 PF15569.1 EMC83317.1 - 0.11 12.2 0.8 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 21 TMEM51 PF15345.1 EMC83317.1 - 0.28 10.8 0.1 0.28 10.8 0.0 2.2 2 1 0 2 2 2 0 Transmembrane protein 51 DUF3708 PF12501.3 EMC83317.1 - 0.4 10.5 4.5 0.22 11.3 0.2 2.5 2 2 1 3 3 3 0 Phosphate ATP-binding cassette transporter MCPsignal PF00015.16 EMC83317.1 - 0.61 9.5 9.4 0.47 9.9 1.4 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2383 PF09537.5 EMC83317.1 - 0.66 10.2 6.7 10 6.4 0.3 3.5 3 2 0 3 3 3 0 Domain of unknown function (DUF2383) Mit_KHE1 PF10173.4 EMC83317.1 - 1.2 9.0 5.3 3.6 7.4 3.7 1.9 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related PilJ PF13675.1 EMC83317.1 - 2.5 8.4 9.9 1.2 9.5 2.1 2.8 2 2 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term GAS PF13851.1 EMC83317.1 - 2.6 7.1 19.1 5.5 6.1 5.4 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cob_adeno_trans PF01923.13 EMC83317.1 - 2.9 7.6 7.4 2.5 7.8 0.9 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF4044 PF13253.1 EMC83317.1 - 2.9 7.1 4.5 20 4.4 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) FliJ PF02050.11 EMC83317.1 - 4.5 7.3 25.9 0.53 10.3 3.3 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein DUF342 PF03961.8 EMC83317.1 - 6 5.1 9.9 0.49 8.7 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) CN_hydrolase PF00795.17 EMC83318.1 - 9.1e-15 54.4 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sec10 PF07393.6 EMC83318.1 - 0.052 11.7 0.0 0.069 11.3 0.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 CN_hydrolase PF00795.17 EMC83319.1 - 1.4e-14 53.8 0.0 2.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 EMC83320.1 - 4.8e-39 134.0 70.6 4.4e-24 84.8 24.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC83320.1 - 7.4e-07 27.9 11.6 7.4e-07 27.9 8.0 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.14 EMC83320.1 - 0.0014 17.2 14.9 0.07 11.6 0.1 2.4 1 1 1 2 2 2 2 LacY proton/sugar symporter Ribosomal_L7Ae PF01248.21 EMC83321.1 - 8.8e-31 105.2 1.9 1.1e-30 105.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1777 PF08648.7 EMC83322.1 - 0.22 11.2 43.1 0.25 11.0 29.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Nop14 PF04147.7 EMC83322.1 - 2.4 5.9 53.6 2.7 5.7 37.1 1.0 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 EMC83322.1 - 5.2 5.4 88.9 6.1 5.1 61.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HLH PF00010.21 EMC83324.1 - 9.7e-17 60.4 0.2 1.5e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TBP PF00352.16 EMC83325.1 - 7.9e-47 156.5 0.2 3.1e-23 80.9 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMC83325.1 - 2.5e-05 24.2 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Sugar_tr PF00083.19 EMC83326.1 - 1.1e-99 334.0 29.2 2.2e-76 257.2 10.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC83326.1 - 2.6e-28 98.7 34.1 6.2e-25 87.6 14.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EMC83327.1 - 1.8e-67 227.2 0.0 2.3e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83327.1 - 4.1e-31 107.9 0.0 8.4e-31 106.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC83327.1 - 1.4e-07 30.7 0.0 2.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EMC83327.1 - 3.5e-06 27.4 0.1 3.5e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 EMC83327.1 - 0.0017 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_fiss_reg PF05308.6 EMC83327.1 - 0.02 14.3 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PX PF00787.19 EMC83327.1 - 0.045 13.5 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 PX domain APH PF01636.18 EMC83327.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aldedh PF00171.17 EMC83328.1 - 4.2e-173 575.9 0.0 4.9e-173 575.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4487 PF14868.1 EMC83328.1 - 0.13 10.9 0.1 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) GTP_EFTU PF00009.22 EMC83329.1 - 3.4e-49 166.8 0.0 6.4e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EMC83329.1 - 4e-23 81.3 1.4 1.6e-22 79.3 1.5 1.7 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EMC83329.1 - 1.6e-19 69.8 0.9 5.5e-19 68.1 0.0 2.4 2 1 1 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC83329.1 - 4.5e-08 33.0 0.1 2.1e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC83329.1 - 4.5e-07 29.8 0.4 2.6e-06 27.3 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EMC83329.1 - 0.0005 19.6 0.0 0.0015 18.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EMC83329.1 - 0.0033 17.9 7.0 0.0058 17.1 0.1 3.5 3 1 0 3 3 3 1 Miro-like protein MobB PF03205.9 EMC83329.1 - 0.0033 17.1 0.4 0.51 10.0 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EMC83329.1 - 0.025 14.7 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMC83329.1 - 0.38 10.3 0.0 0.38 10.3 0.0 2.7 4 0 0 4 4 4 0 P-loop containing region of AAA domain Cmyb_C PF09316.5 EMC83330.1 - 3.2e-64 215.6 4.3 7.2e-64 214.4 2.7 1.9 1 1 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 EMC83330.1 - 8.2e-52 173.0 19.0 4.3e-17 61.9 1.3 4.2 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC83330.1 - 2.1e-42 143.0 19.6 3.5e-19 68.6 1.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMSTEN PF07988.7 EMC83330.1 - 3e-29 100.0 0.6 6e-29 99.0 0.4 1.6 1 0 0 1 1 1 1 LMSTEN motif Rap1_C PF11626.3 EMC83330.1 - 0.085 12.7 9.2 6.3 6.7 1.9 3.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.5 EMC83330.1 - 0.19 11.4 0.1 0.74 9.5 0.0 2.1 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) WD40 PF00400.27 EMC83331.1 - 1.1e-32 110.6 6.8 3.5e-10 39.3 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat SH3_1 PF00018.23 EMC83331.1 - 4.6e-17 61.1 0.0 1.2e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC83331.1 - 3.2e-15 55.4 0.0 7.4e-15 54.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC83331.1 - 1.5e-10 40.3 0.0 3.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4648 PF15505.1 EMC83331.1 - 0.00014 22.1 2.4 0.00041 20.5 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4648) PDEase_I PF00233.14 EMC83332.1 - 3.5e-62 210.2 0.5 4.7e-62 209.8 0.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SNARE PF05739.14 EMC83332.1 - 0.11 12.2 0.7 0.23 11.1 0.5 1.6 1 0 0 1 1 1 0 SNARE domain Mito_fiss_reg PF05308.6 EMC83333.1 - 4e-58 196.7 0.4 5.1e-58 196.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator THRAP3_BCLAF1 PF15440.1 EMC83334.1 - 3.7e-179 597.4 110.0 3.7e-179 597.4 76.2 2.5 3 0 0 3 3 3 1 THRAP3/BCLAF1 family Arm PF00514.18 EMC83335.1 - 0.0034 17.1 0.2 0.99 9.3 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Mo25 PF08569.6 EMC83335.1 - 0.028 13.4 0.9 0.032 13.2 0.6 1.1 1 0 0 1 1 1 0 Mo25-like SAPS PF04499.10 EMC83335.1 - 0.046 12.3 0.4 0.054 12.1 0.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein mRNA_stabil PF13929.1 EMC83335.1 - 0.1 11.5 0.6 1.3 7.8 0.1 2.0 1 1 1 2 2 2 0 mRNA stabilisation MAP7 PF05672.6 EMC83336.1 - 5.1e-55 185.4 78.3 5.1e-55 185.4 54.3 3.7 3 0 0 3 3 3 2 MAP7 (E-MAP-115) family WD40 PF00400.27 EMC83337.1 - 1.1e-38 129.7 11.9 3.4e-09 36.2 0.5 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC83337.1 - 9.3e-05 22.2 0.1 0.0011 18.7 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC83337.1 - 0.2 9.7 2.1 16 3.4 0.0 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TPT PF03151.11 EMC83338.1 - 3e-07 30.1 13.5 4.2e-07 29.7 9.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF4199 PF13858.1 EMC83338.1 - 0.013 15.4 0.6 0.065 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2776 PF10951.3 EMC83338.1 - 0.073 12.1 8.6 0.047 12.7 4.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2776) 7TMR-DISM_7TM PF07695.6 EMC83338.1 - 5.3 6.6 11.0 0.32 10.6 2.5 1.8 1 1 0 2 2 2 0 7TM diverse intracellular signalling Tissue_fac PF01108.12 EMC83339.1 - 7.1e-27 93.2 0.1 1.9e-26 91.8 0.1 1.8 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 EMC83339.1 - 2.3e-21 75.8 1.8 2.7e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 EMC83339.1 - 0.00028 20.9 2.7 0.18 11.9 0.1 3.4 3 1 0 3 3 3 2 Fibronectin type III domain Tissue_fac PF01108.12 EMC83340.1 - 3.5e-28 97.4 1.0 7.6e-28 96.3 0.7 1.6 1 1 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 EMC83340.1 - 2.8e-20 72.3 1.3 4e-20 71.8 0.1 1.8 2 1 1 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 EMC83340.1 - 0.41 10.8 2.8 21 5.3 0.0 3.5 4 0 0 4 4 4 0 Fibronectin type III domain Tissue_fac PF01108.12 EMC83341.1 - 1.5e-18 66.5 0.3 1.7e-18 66.3 0.2 1.1 1 0 0 1 1 1 1 Tissue factor HLH PF00010.21 EMC83342.1 - 3.2e-12 45.9 0.2 5.6e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-A20 PF01754.11 EMC83343.1 - 2.8e-45 151.4 77.0 5.5e-11 41.8 2.7 7.9 7 0 0 7 7 7 7 A20-like zinc finger OTU PF02338.14 EMC83343.1 - 6.8e-27 94.4 0.0 2.1e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease PMP22_Claudin PF00822.15 EMC83344.1 - 9.9e-09 35.0 9.5 1.3e-08 34.7 6.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 EMC83344.1 - 0.0011 19.0 7.6 0.0027 17.7 5.2 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 EMC83344.1 - 0.014 15.1 9.9 0.021 14.5 6.8 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PalH PF08733.5 EMC83344.1 - 0.027 13.3 4.3 0.039 12.8 3.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Pox_A14 PF05767.7 EMC83344.1 - 0.39 10.6 8.1 0.071 13.0 2.9 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PMP22_Claudin PF00822.15 EMC83345.1 - 4.4e-11 42.7 3.7 6.3e-11 42.2 2.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC83345.1 - 2.3e-06 27.4 8.3 3.9e-06 26.6 5.8 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 EMC83345.1 - 0.00039 20.4 6.3 0.00097 19.1 4.3 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PalH PF08733.5 EMC83345.1 - 0.065 12.0 3.7 0.087 11.6 2.6 1.1 1 0 0 1 1 1 0 PalH/RIM21 LRR19-TM PF15176.1 EMC83345.1 - 0.22 11.2 0.5 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Pox_A14 PF05767.7 EMC83345.1 - 2 8.4 9.4 1.6 8.7 4.0 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 NHS PF15273.1 EMC83346.1 - 1.8e-259 862.9 89.8 1.8e-259 862.9 62.3 3.4 4 0 0 4 4 4 1 NHS-like DUF4061 PF13270.1 EMC83347.1 - 4.9e-37 125.9 3.8 6.6e-37 125.4 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) tRNA-synt_His PF13393.1 EMC83347.1 - 0.025 13.6 0.5 0.033 13.2 0.3 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF508 PF04370.7 EMC83347.1 - 0.29 10.7 2.7 2.7 7.6 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF508) EF-hand_4 PF12763.2 EMC83348.1 - 1.3e-12 47.3 0.6 3.4e-12 45.9 0.0 2.0 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EMC83348.1 - 0.0011 18.0 0.0 0.0024 17.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EMC83348.1 - 0.0019 17.7 0.1 0.0044 16.6 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EMC83348.1 - 0.0033 17.5 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC83348.1 - 0.041 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Costars PF14705.1 EMC83349.1 - 2.4e-32 110.7 0.1 2.6e-32 110.6 0.1 1.0 1 0 0 1 1 1 1 Costars Arf PF00025.16 EMC83350.1 - 3.7e-60 202.1 0.1 4.2e-60 201.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC83350.1 - 1.2e-12 47.4 0.0 1.4e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC83350.1 - 2.8e-11 42.7 1.3 4.1e-08 32.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMC83350.1 - 7.6e-11 41.6 0.0 9.4e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC83350.1 - 1.9e-10 40.3 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC83350.1 - 5.1e-09 36.6 0.0 7.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC83350.1 - 1.6e-06 28.0 0.0 2.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMC83350.1 - 0.0031 16.6 0.6 0.0084 15.1 0.4 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EMC83350.1 - 0.024 14.4 0.1 0.051 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EMC83350.1 - 0.092 12.1 0.0 0.88 8.9 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RhoGEF PF00621.15 EMC83351.1 - 1.1e-38 132.8 0.1 2e-38 132.0 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EMC83351.1 - 0.00014 21.8 0.1 0.0011 18.8 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMC83351.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 PH domain zf-Di19 PF05605.7 EMC83351.1 - 0.053 13.6 1.3 0.22 11.6 0.2 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3715 PF12509.3 EMC83352.1 - 7.8e-59 198.2 0.7 6.8e-58 195.1 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3715) CCDC66 PF15236.1 EMC83353.1 - 1.6e-53 180.5 31.0 1.6e-53 180.5 21.5 5.1 5 0 0 5 5 5 1 Coiled-coil domain-containing protein 66 Myosin_tail_1 PF01576.14 EMC83354.1 - 8.8e-18 63.4 2.5 1.1e-17 63.1 1.7 1.0 1 0 0 1 1 1 1 Myosin tail DUF3496 PF12001.3 EMC83354.1 - 0.16 12.2 2.5 0.26 11.5 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Caveolin PF01146.12 EMC83355.1 - 2.1e-65 218.7 1.5 2.6e-65 218.5 1.0 1.0 1 0 0 1 1 1 1 Caveolin 7tm_1 PF00001.16 EMC83356.1 - 4e-42 144.1 15.7 4.4e-42 143.9 10.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83356.1 - 0.00077 18.6 11.5 0.0012 18.0 8.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SAP PF02037.22 EMC83357.1 - 2.6e-11 42.7 0.7 7e-11 41.3 0.1 2.0 2 0 0 2 2 2 1 SAP domain zf-RING_6 PF14835.1 EMC83357.1 - 3.8e-09 36.2 7.1 2.1e-08 33.7 2.5 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EMC83357.1 - 6.8e-07 28.8 15.8 9.9e-07 28.3 7.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC83357.1 - 7.7e-07 29.0 11.3 7.7e-07 29.0 7.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC83357.1 - 7.4e-06 25.6 9.5 7.4e-06 25.6 6.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EMC83357.1 - 8.5e-06 25.3 10.0 8.5e-06 25.3 6.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC83357.1 - 7.3e-05 22.3 12.0 0.00017 21.1 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Mob_synth_C PF06463.8 EMC83357.1 - 0.014 15.0 0.4 0.014 15.0 0.3 2.6 3 0 0 3 3 3 0 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 EMC83357.1 - 0.058 13.5 11.4 0.045 13.8 5.8 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC83357.1 - 0.11 12.4 15.2 0.062 13.1 8.0 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CRS1_YhbY PF01985.16 EMC83357.1 - 0.15 12.0 3.4 15 5.6 0.1 3.3 3 0 0 3 3 3 0 CRS1 / YhbY (CRM) domain zf-Apc11 PF12861.2 EMC83357.1 - 0.6 9.9 5.6 2 8.3 3.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger VHL PF01847.11 EMC83358.1 - 1.5e-41 141.5 0.2 1.7e-41 141.3 0.1 1.0 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein STAT2_C PF12188.3 EMC83358.1 - 0.12 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal Motilin_assoc PF04643.7 EMC83359.1 - 1e-22 79.3 0.2 3.5e-22 77.6 0.0 1.9 2 0 0 2 2 2 1 Motilin/ghrelin-associated peptide Motilin_ghrelin PF04644.7 EMC83359.1 - 0.0026 17.5 0.8 0.0041 16.8 0.5 1.3 1 0 0 1 1 1 1 Motilin/ghrelin WD40 PF00400.27 EMC83360.1 - 1.4e-48 161.0 22.9 3.6e-10 39.3 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EMC83360.1 - 0.095 12.4 11.7 0.26 11.0 0.6 4.3 2 2 3 5 5 5 0 Transcription factor IIIC subunit delta N-term TIP120 PF08623.5 EMC83361.1 - 1.3e-60 203.8 4.5 4.9e-59 198.6 0.2 4.9 5 1 2 7 7 7 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EMC83361.1 - 3e-26 91.5 10.9 0.0024 18.0 0.0 10.7 7 4 2 9 9 9 6 HEAT repeats HEAT PF02985.17 EMC83361.1 - 5.6e-23 78.9 17.2 0.015 15.3 0.0 12.8 13 0 0 13 13 12 6 HEAT repeat HEAT_EZ PF13513.1 EMC83361.1 - 9.8e-18 64.0 21.2 0.0075 16.7 0.1 13.9 13 5 6 19 19 17 4 HEAT-like repeat Cnd1 PF12717.2 EMC83361.1 - 9.7e-13 48.3 7.3 0.13 12.1 0.0 7.2 5 2 1 7 7 7 4 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EMC83361.1 - 2.3e-12 46.8 2.7 0.076 12.9 0.0 6.9 4 2 2 6 6 6 4 UME (NUC010) domain Adaptin_N PF01602.15 EMC83361.1 - 2.2e-10 39.4 15.9 0.0041 15.5 2.6 5.8 3 3 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 EMC83361.1 - 8.4e-07 28.5 4.3 0.075 12.3 0.0 6.8 7 3 1 8 8 8 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 EMC83361.1 - 2.7e-06 27.6 1.1 13 6.2 0.0 7.5 7 3 3 10 10 8 0 Vacuolar 14 Fab1-binding region DUF1981 PF09324.5 EMC83361.1 - 3.3e-05 23.3 0.9 0.82 9.2 0.0 5.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Cnd3 PF12719.2 EMC83361.1 - 0.00077 18.5 8.4 0.33 9.8 0.5 5.1 4 2 1 5 5 5 1 Nuclear condensing complex subunits, C-term domain RasGEF_N_2 PF14663.1 EMC83361.1 - 0.0017 18.2 3.1 2.4 8.1 0.1 5.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DRIM PF07539.7 EMC83361.1 - 0.025 13.9 0.2 0.13 11.6 0.1 2.3 2 0 0 2 2 2 0 Down-regulated in metastasis VHS PF00790.14 EMC83361.1 - 0.029 13.9 1.3 1.5 8.4 0.0 3.5 4 0 0 4 4 3 0 VHS domain DUF3385 PF11865.3 EMC83361.1 - 0.043 13.7 6.0 0.34 10.8 0.0 5.3 7 2 1 8 8 8 0 Domain of unknown function (DUF3385) Arm PF00514.18 EMC83361.1 - 0.059 13.2 10.5 10 6.1 0.0 7.1 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 EMC83361.1 - 0.13 12.2 11.4 1.7 8.6 0.0 6.6 6 3 2 8 8 8 0 Rix1 complex component involved in 60S ribosome maturation HhH-GPD PF00730.20 EMC83362.1 - 1.1e-07 32.0 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4303 PF14136.1 EMC83362.1 - 0.081 12.5 0.3 3.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) WD40 PF00400.27 EMC83363.1 - 1.6e-17 62.6 13.0 0.00086 19.0 0.1 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMC83363.1 - 6.6e-06 25.1 4.6 0.018 13.8 0.0 4.6 5 0 0 5 5 5 2 Coatomer WD associated region Clathrin PF00637.15 EMC83363.1 - 0.011 15.3 0.5 3 7.4 0.0 3.5 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_7 PF13176.1 EMC83363.1 - 0.033 13.9 0.1 0.033 13.9 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EMC83363.1 - 0.044 13.6 6.7 0.037 13.8 2.7 2.4 2 0 0 2 2 2 0 Ring finger domain TPR_2 PF07719.12 EMC83363.1 - 0.2 11.6 21.2 0.18 11.8 0.5 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC83363.1 - 2.6 8.0 11.1 0.97 9.4 0.1 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC83363.1 - 4.1 8.3 11.2 32 5.5 0.3 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EMC83363.1 - 5 6.8 16.9 0.043 13.4 1.3 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Tmemb_cc2 PF10267.4 EMC83364.1 - 2.4e-179 596.0 14.6 2.4e-179 596.0 10.1 1.4 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein TMPIT PF07851.8 EMC83364.1 - 2.3 7.1 14.5 3.9 6.4 3.3 2.6 2 0 0 2 2 2 0 TMPIT-like protein DIRP PF06584.8 EMC83364.1 - 8.4 6.3 8.2 0.34 10.7 0.2 2.5 2 1 0 2 2 2 0 DIRP TRH PF05438.7 EMC83366.1 - 5.1e-59 199.2 10.4 4.5e-56 189.5 4.0 2.0 2 0 0 2 2 2 2 Thyrotropin-releasing hormone (TRH) Med2 PF11214.3 EMC83366.1 - 0.029 14.4 0.2 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 Rbsn PF11464.3 EMC83367.1 - 1.4e-43 146.1 15.7 9.1e-22 76.3 0.4 2.6 2 0 0 2 2 2 2 Rabenosyn Rab binding domain FYVE PF01363.16 EMC83367.1 - 1.1e-18 66.8 6.3 2.7e-18 65.6 4.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.14 EMC83367.1 - 0.0024 17.5 0.4 0.0024 17.5 0.3 2.8 3 1 1 4 4 4 1 Hydrogenase expression/synthesis hypA family TerY-C PF15616.1 EMC83367.1 - 0.0097 15.8 1.6 0.059 13.3 0.1 2.4 2 0 0 2 2 2 1 TerY-C metal binding domain RNA_POL_M_15KD PF02150.11 EMC83367.1 - 0.037 13.7 6.0 0.032 13.9 0.8 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-RING_3 PF14369.1 EMC83367.1 - 0.2 11.6 3.6 0.33 10.9 0.1 2.5 2 0 0 2 2 2 0 zinc-finger HlyD_2 PF12700.2 EMC83367.1 - 8.8 5.3 11.8 0.37 9.8 3.2 2.0 2 0 0 2 2 2 0 HlyD family secretion protein Hormone_recep PF00104.25 EMC83368.1 - 3.8e-36 124.1 2.2 6.7e-36 123.3 1.5 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC83368.1 - 4.3e-32 110.1 16.3 8.5e-32 109.2 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) XS PF03468.9 EMC83368.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 XS domain DUF4573 PF15140.1 EMC83370.1 - 4.2e-13 49.2 0.0 1.8e-06 27.6 0.0 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) DUF2635 PF10948.3 EMC83370.1 - 3.5e-07 29.4 0.0 27 4.1 0.0 6.2 1 1 7 8 8 8 4 Protein of unknown function (DUF2635) SR-25 PF10500.4 EMC83370.1 - 1.2 8.5 7.7 1.3e+02 1.9 0.1 5.6 1 1 6 7 7 7 0 Nuclear RNA-splicing-associated protein MSSP PF03940.8 EMC83370.1 - 5.6 6.4 83.3 1.5e+04 -38.9 57.8 3.8 1 1 0 1 1 1 0 Male specific sperm protein Dynamitin PF04912.9 EMC83371.1 - 2.8e-128 428.0 5.2 3.1e-128 427.8 3.6 1.0 1 0 0 1 1 1 1 Dynamitin FlaC_arch PF05377.6 EMC83371.1 - 0.23 11.3 8.0 12 5.9 0.2 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF3763 PF12592.3 EMC83371.1 - 0.35 10.5 0.0 0.35 10.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3763) Baculo_PEP_C PF04513.7 EMC83371.1 - 3.9 7.3 15.7 2.8 7.7 0.7 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.8 EMC83371.1 - 4.1 8.1 10.5 15 6.3 0.4 4.1 3 1 0 4 4 4 0 Occludin homology domain GrpE PF01025.14 EMC83371.1 - 7.5 6.0 10.4 0.51 9.8 0.4 3.0 2 1 0 2 2 2 0 GrpE TipAS PF07739.8 EMC83371.1 - 9.5 6.5 7.6 7.3 6.9 0.3 3.3 3 1 1 4 4 4 0 TipAS antibiotic-recognition domain Pkinase PF00069.20 EMC83372.1 - 1.4e-44 152.2 0.0 1.7e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83372.1 - 7.6e-30 103.8 0.0 9.1e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EMC83372.1 - 0.068 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMC83372.1 - 0.091 12.4 1.1 6.1 6.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Flavodoxin_1 PF00258.20 EMC83373.1 - 1.7e-29 102.6 0.0 2.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EMC83373.1 - 6.1e-12 45.4 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_5 PF12724.2 EMC83373.1 - 2.2e-06 27.7 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain FAST_1 PF06743.10 EMC83374.1 - 5.8e-22 77.1 2.4 5.8e-22 77.1 1.7 4.3 3 1 0 4 4 4 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 EMC83374.1 - 1.1e-18 67.3 0.0 4.9e-18 65.2 0.0 2.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 RAP PF08373.5 EMC83374.1 - 2.2e-13 49.7 0.0 4.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RAP domain RNA_pol_N PF01194.12 EMC83374.1 - 0.012 15.5 0.2 0.037 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit GRAM PF02893.15 EMC83374.1 - 0.018 14.5 0.2 0.065 12.7 0.1 2.0 2 0 0 2 2 2 0 GRAM domain DUF776 PF05604.6 EMC83375.1 - 8.6e-48 162.9 8.9 4e-47 160.7 4.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF776) DUF776 PF05604.6 EMC83376.1 - 5e-56 189.7 14.4 5e-56 189.7 10.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF776) MORN PF02493.15 EMC83377.1 - 1.7e-34 115.5 69.5 7e-07 28.6 2.2 8.7 9 0 0 9 9 9 8 MORN repeat DDRGK PF09756.4 EMC83378.1 - 0.87 8.9 2.6 1.1 8.6 1.8 1.1 1 0 0 1 1 1 0 DDRGK domain 7tm_1 PF00001.16 EMC83379.1 - 4.9e-09 35.7 11.0 6.2e-09 35.3 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC83379.1 - 0.013 14.6 1.7 0.013 14.6 1.2 1.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 EMC83379.1 - 0.21 10.6 3.0 0.26 10.4 2.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DC_STAMP PF07782.8 EMC83380.1 - 2.2e-32 112.2 1.2 4.5e-32 111.2 0.9 1.5 1 0 0 1 1 1 1 DC-STAMP-like protein G2F PF07474.7 EMC83380.1 - 0.2 11.0 1.4 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 G2F domain Transglut_C PF00927.17 EMC83381.1 - 2.6e-30 104.5 0.2 3e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 EMC83381.1 - 1.6e-27 95.9 0.0 4e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 EMC83381.1 - 1.4e-17 63.9 0.2 3.8e-17 62.5 0.2 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily GCIP PF13324.1 EMC83382.1 - 8.8e-76 254.7 0.8 1e-75 254.5 0.6 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting AAA_12 PF13087.1 EMC83383.1 - 5.4e-39 133.6 0.0 1.6e-38 132.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMC83383.1 - 1.1e-28 100.3 9.9 1.1e-26 93.8 6.8 2.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC83383.1 - 1.6e-09 37.3 0.0 4.8e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMC83383.1 - 2.3e-07 30.5 0.4 0.00038 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EMC83383.1 - 0.00032 20.5 0.0 0.00094 19.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EMC83383.1 - 0.0012 17.8 3.6 0.0019 17.2 0.0 2.9 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMC83383.1 - 0.004 16.5 1.1 0.023 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EMC83383.1 - 0.0049 16.1 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.24 EMC83383.1 - 0.017 14.5 0.5 0.092 12.2 0.0 2.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC83383.1 - 0.056 13.5 1.3 0.73 9.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF3361 PF11841.3 EMC83384.1 - 1.3e-73 246.0 5.8 2.9e-73 244.8 4.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 EMC83384.1 - 3.8e-46 156.7 0.2 6.6e-46 155.9 0.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family FERM_N PF09379.5 EMC83384.1 - 0.1 12.6 0.0 0.59 10.2 0.0 2.3 1 1 0 1 1 1 0 FERM N-terminal domain GDE_C PF06202.9 EMC83384.1 - 0.19 10.4 0.9 22 3.6 0.0 3.0 3 0 0 3 3 3 0 Amylo-alpha-1,6-glucosidase TPT PF03151.11 EMC83385.1 - 1e-28 99.8 5.4 1e-28 99.8 3.8 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMC83385.1 - 9e-05 21.5 15.2 0.00016 20.7 10.5 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMC83385.1 - 0.013 15.5 26.3 0.026 14.5 5.6 2.5 2 1 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 EMC83385.1 - 0.28 11.3 18.6 0.8 9.9 2.2 2.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Cadherin PF00028.12 EMC83387.1 - 2.2e-83 274.6 11.3 5e-20 71.5 0.1 5.4 5 1 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC83387.1 - 1.9e-44 151.2 0.2 4.1e-44 150.2 0.2 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC83387.1 - 5e-06 26.0 0.1 0.36 10.4 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like DUF2406 PF10295.4 EMC83387.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) TAS2R PF05296.8 EMC83387.1 - 0.05 12.4 0.1 0.077 11.8 0.1 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) EphA2_TM PF14575.1 EMC83387.1 - 0.084 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.4 EMC83387.1 - 0.12 11.7 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 TNFR_c6 PF00020.13 EMC83389.1 - 8.1e-07 29.0 42.9 1.1e-05 25.3 7.5 4.5 5 0 0 5 5 5 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 EMC83389.1 - 0.0038 16.7 0.6 0.0038 16.7 0.4 4.3 3 2 1 4 4 4 2 GCC2 and GCC3 DUF4222 PF13973.1 EMC83389.1 - 0.068 12.5 0.1 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) HGTP_anticodon PF03129.15 EMC83390.1 - 0.00068 19.5 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Macoilin PF09726.4 EMC83390.1 - 0.004 15.5 0.1 0.0069 14.7 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein zf-RING_5 PF14634.1 EMC83391.1 - 0.00011 21.8 5.0 0.00024 20.7 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC83391.1 - 0.00034 20.2 5.0 0.00087 18.9 3.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC83391.1 - 0.00042 20.1 4.0 0.0014 18.4 2.8 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC83391.1 - 0.00086 19.0 7.7 0.00086 19.0 5.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC83391.1 - 0.0013 18.3 8.8 0.0013 18.3 6.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC83391.1 - 0.0018 17.8 5.8 0.0043 16.6 4.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC83391.1 - 0.0028 17.6 6.8 0.0086 16.0 4.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMC83391.1 - 4.7 6.8 14.0 0.043 13.3 4.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PCIF1_WW PF12237.3 EMC83392.1 - 5.5e-71 237.4 0.1 8.9e-71 236.7 0.1 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.21 EMC83392.1 - 2.7e-08 33.5 0.5 5.5e-08 32.5 0.3 1.5 1 0 0 1 1 1 1 WW domain LBP_BPI_CETP_C PF02886.12 EMC83393.1 - 1.2e-50 171.9 0.0 2e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 EMC83393.1 - 3.9e-28 97.8 0.1 1.5e-27 95.9 0.1 1.9 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain 7kD_coat PF02495.12 EMC83393.1 - 0.07 12.5 0.1 11 5.4 0.0 2.5 2 0 0 2 2 2 0 7kD viral coat protein Peptidase_S10 PF00450.17 EMC83394.1 - 1.8e-106 356.8 0.3 2e-106 356.6 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase SOCS_box PF07525.11 EMC83395.1 - 2.5e-08 33.6 2.0 2.5e-08 33.6 1.4 2.1 2 0 0 2 2 2 1 SOCS box SWIM PF04434.12 EMC83396.1 - 0.0012 18.2 0.5 0.0012 18.2 0.3 2.8 3 0 0 3 3 3 1 SWIM zinc finger Acyl_CoA_thio PF02551.10 EMC83397.1 - 1.1e-30 105.9 0.0 4.1e-27 94.4 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 EMC83397.1 - 1.2e-28 100.5 0.0 1.4e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily EF-hand_1 PF00036.27 EMC83398.1 - 1.6e-30 102.0 24.3 2e-08 32.9 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC83398.1 - 1.3e-28 98.9 11.8 8.9e-16 57.7 3.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC83398.1 - 4.7e-25 86.9 20.0 4.4e-13 48.6 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMC83398.1 - 6.3e-25 84.7 13.7 2.9e-07 29.7 0.3 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC83398.1 - 7.2e-21 72.5 20.0 4.7e-06 25.7 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMC83398.1 - 5.7e-15 54.9 0.5 1.5e-06 28.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC83398.1 - 6.3e-06 25.8 9.8 0.023 14.4 0.4 3.4 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC83398.1 - 7e-06 26.0 0.3 0.0033 17.4 0.3 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SpoVIF PF14069.1 EMC83398.1 - 0.0019 17.9 0.4 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Stage VI sporulation protein F TerB PF05099.8 EMC83398.1 - 0.0037 16.9 3.8 0.058 13.1 0.9 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB FlgD PF03963.9 EMC83398.1 - 0.012 15.6 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region HopW1-1 PF15457.1 EMC83398.1 - 0.021 13.9 0.1 0.65 8.9 0.0 2.0 1 1 1 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA PTS_2-RNA PF01885.11 EMC83398.1 - 0.047 12.9 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1456 PF07308.8 EMC83398.1 - 0.26 11.3 3.5 4 7.5 0.1 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1456) UQ_con PF00179.21 EMC83399.1 - 3e-34 117.4 0.0 3.2e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC83399.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC83399.1 - 0.0046 16.6 0.0 0.009 15.6 0.0 1.5 1 1 0 1 1 1 1 UEV domain Kunitz_BPTI PF00014.18 EMC83401.1 - 3.1e-17 62.5 14.1 3.1e-17 62.5 9.8 1.6 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WAP PF00095.16 EMC83401.1 - 3e-05 23.9 12.1 3e-05 23.9 8.4 2.5 3 0 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' zf-C4 PF00105.13 EMC83401.1 - 2.3 8.5 12.9 0.78 10.0 7.3 1.6 1 1 0 1 1 1 0 Zinc finger, C4 type (two domains) WAP PF00095.16 EMC83402.1 - 9.8e-44 147.0 101.8 5.9e-11 42.1 11.1 5.1 5 0 0 5 5 5 5 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.16 EMC83403.1 - 1.6e-21 76.0 39.7 1.5e-11 44.0 10.8 2.1 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Kunitz_BPTI PF00014.18 EMC83404.1 - 1.5e-21 76.3 4.8 1.5e-21 76.3 3.3 2.7 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WAP PF00095.16 EMC83404.1 - 1.3e-18 66.6 43.5 4.9e-10 39.2 9.1 3.3 3 0 0 3 3 3 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' CTNNBL PF08216.6 EMC83405.1 - 6e-44 148.0 3.0 6e-44 148.0 2.1 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EMC83405.1 - 0.00014 21.5 3.6 2.2 8.2 0.1 3.8 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat DUF4020 PF13212.1 EMC83405.1 - 0.017 14.6 0.5 0.093 12.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) I-set PF07679.11 EMC83406.1 - 1.1e-09 37.9 0.2 1.4e-07 31.2 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 EMC83406.1 - 1.2e-08 34.8 0.1 1.5e-07 31.3 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC83406.1 - 3.1e-05 24.0 0.1 0.0054 16.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC83406.1 - 0.00025 21.5 0.0 0.00068 20.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC83406.1 - 0.00028 20.9 0.0 0.00071 19.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain HEAT_2 PF13646.1 EMC83407.1 - 8.1e-09 35.6 7.0 0.0038 17.4 0.3 4.6 4 1 0 4 4 4 2 HEAT repeats VHS PF00790.14 EMC83407.1 - 4.7e-05 23.0 3.7 0.37 10.4 0.0 4.4 5 0 0 5 5 5 3 VHS domain HEAT PF02985.17 EMC83407.1 - 0.00015 21.5 17.7 1.8 8.8 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 EMC83407.1 - 0.038 13.8 1.1 32 4.5 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EMC83407.1 - 0.068 13.0 4.8 2 8.2 0.2 3.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EMC83407.1 - 0.095 13.0 0.1 11 6.4 0.0 3.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CTD_bind PF04818.8 EMC83408.1 - 4.3e-26 90.9 0.4 6.6e-25 87.1 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CP_ATPgrasp_2 PF14403.1 EMC83408.1 - 0.014 14.0 0.6 0.018 13.6 0.4 1.1 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 DUF2294 PF10057.4 EMC83408.1 - 0.082 12.5 0.9 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) AAA_13 PF13166.1 EMC83408.1 - 0.14 10.5 6.1 0.18 10.2 4.3 1.2 1 0 0 1 1 1 0 AAA domain FemAB PF02388.11 EMC83408.1 - 0.35 9.5 5.8 0.076 11.6 1.5 1.6 2 0 0 2 2 2 0 FemAB family Swi5 PF07061.6 EMC83408.1 - 0.57 10.0 7.8 5.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Swi5 FimP PF09766.4 EMC83408.1 - 1 8.3 13.5 0.098 11.7 5.4 1.9 2 1 0 2 2 2 0 Fms-interacting protein Dzip-like_N PF13815.1 EMC83408.1 - 2.7 7.8 8.8 0.48 10.2 2.1 2.4 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF2408 PF10303.4 EMC83408.1 - 5.2 7.1 9.4 2.9 8.0 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Transglut_C PF00927.17 EMC83409.1 - 2e-38 130.7 0.1 1e-24 86.5 0.0 3.5 3 1 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 EMC83409.1 - 2.2e-26 92.2 0.0 4e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 EMC83409.1 - 8.8e-18 64.5 0.6 1.7e-17 63.6 0.4 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF3498 PF12004.3 EMC83410.1 - 0.024 13.8 0.1 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) CRAL_TRIO_2 PF13716.1 EMC83411.1 - 7.4e-08 32.4 0.0 1.6e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain LBP_BPI_CETP_C PF02886.12 EMC83412.1 - 4.8e-66 222.3 0.0 8.5e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 EMC83412.1 - 4.7e-41 139.8 0.1 1.8e-40 137.9 0.0 2.0 3 0 0 3 3 3 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.6 EMC83412.1 - 0.007 15.2 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) Radical_SAM PF04055.16 EMC83413.1 - 1.3e-37 129.5 0.0 2.5e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 EMC83413.1 - 6e-30 102.9 0.0 1.2e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 EMC83413.1 - 1.7e-12 46.9 0.0 3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.1 EMC83413.1 - 0.15 12.2 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain LBP_BPI_CETP PF01273.20 EMC83414.1 - 2.6e-35 121.1 4.6 3.5e-23 81.7 0.2 2.6 2 0 0 2 2 2 2 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.12 EMC83414.1 - 2.8e-22 79.1 3.4 4.7e-22 78.3 0.6 2.2 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP_C PF02886.12 EMC83416.1 - 3.6e-11 42.7 3.1 3.6e-11 42.7 2.2 2.4 2 1 1 3 3 3 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 EMC83416.1 - 2.8e-06 26.7 1.9 1.4e-05 24.4 0.1 3.0 3 1 1 4 4 4 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP PF01273.20 EMC83417.1 - 1.9e-19 69.6 8.4 1.9e-19 69.6 5.8 2.2 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.12 EMC83417.1 - 2.8e-11 43.1 0.4 2.8e-11 43.1 0.2 2.2 2 1 1 3 3 3 1 LBP / BPI / CETP family, C-terminal domain EB1 PF03271.12 EMC83418.1 - 3.9e-17 62.0 1.0 1.5e-16 60.1 0.5 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 EMC83418.1 - 1.3e-12 47.6 0.3 1.7e-11 44.0 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC83418.1 - 0.029 14.0 0.0 0.082 12.5 0.0 1.7 2 0 0 2 2 2 0 CAMSAP CH domain PWWP PF00855.12 EMC83419.1 - 2.9e-19 69.0 0.7 8.7e-19 67.5 0.1 2.0 2 0 0 2 2 2 1 PWWP domain DNA_methylase PF00145.12 EMC83419.1 - 4e-11 42.6 0.0 3.5e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase HCaRG PF07258.9 EMC83420.1 - 6.1e-34 117.1 0.8 6.8e-34 116.9 0.6 1.0 1 0 0 1 1 1 1 HCaRG protein ASXH PF13919.1 EMC83422.1 - 1.8e-50 170.3 0.2 4.3e-50 169.0 0.1 1.7 1 0 0 1 1 1 1 Asx homology domain PHD_3 PF13922.1 EMC83422.1 - 6e-24 84.0 9.9 4.1e-23 81.3 6.9 2.5 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.8 EMC83422.1 - 9.9e-14 51.4 0.0 2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain TT_ORF2a PF08197.6 EMC83422.1 - 0.62 9.8 7.3 18 5.1 2.4 2.9 2 0 0 2 2 2 0 pORF2a truncated protein Kinesin PF00225.18 EMC83423.1 - 6.6e-121 403.1 1.3 6.6e-121 403.1 0.9 2.1 2 0 0 2 2 2 1 Kinesin motor domain zf-H2C2_2 PF13465.1 EMC83424.1 - 2e-23 81.4 51.0 1.3e-05 25.2 3.0 7.7 7 1 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC83424.1 - 1.1e-18 66.1 52.2 0.00053 20.1 1.7 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC83424.1 - 9e-18 63.4 59.7 0.00013 22.0 1.2 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC83424.1 - 6.7e-05 22.6 0.2 6.7e-05 22.6 0.1 6.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83424.1 - 0.00021 21.3 32.2 0.032 14.3 0.4 6.3 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMC83424.1 - 0.0027 17.7 32.1 0.018 15.1 4.6 4.8 1 1 5 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EMC83424.1 - 0.061 13.5 21.4 1.6 9.0 0.1 5.2 5 0 0 5 5 4 0 Zinc-finger of C2H2 type C1_1 PF00130.17 EMC83424.1 - 0.066 12.9 14.6 0.17 11.6 2.8 3.8 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met2 PF12907.2 EMC83424.1 - 0.067 13.1 0.2 0.067 13.1 0.2 4.2 4 1 1 5 5 4 0 Zinc-binding Equine_IAV_S2 PF06502.6 EMC83424.1 - 0.13 12.1 0.3 0.39 10.6 0.2 1.8 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein zf-C2H2_2 PF12756.2 EMC83424.1 - 0.16 12.1 35.4 0.97 9.5 1.1 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.5 EMC83424.1 - 1.3 9.5 7.9 15 6.2 0.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) PyrI_C PF02748.10 EMC83424.1 - 1.5 8.2 13.0 0.69 9.3 0.2 4.1 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ADK_lid PF05191.9 EMC83424.1 - 3.1 7.5 13.7 1.7 8.3 0.2 3.7 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-CHCC PF10276.4 EMC83424.1 - 5.6 6.8 16.1 12 5.8 0.5 4.3 4 0 0 4 4 4 0 Zinc-finger domain EMP70 PF02990.11 EMC83425.1 - 5.9e-229 760.8 13.5 7.6e-229 760.4 9.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.1 EMC83425.1 - 0.38 10.6 0.0 0.38 10.6 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF4229) Pkinase_Tyr PF07714.12 EMC83426.1 - 5.4e-96 320.6 0.0 7e-96 320.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC83426.1 - 1.4e-49 168.5 0.0 1.8e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC83426.1 - 1.9e-24 85.2 0.0 3.8e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC83426.1 - 1.1e-15 56.7 0.0 2.4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC83426.1 - 1.3e-14 53.4 0.0 3.1e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC83426.1 - 6.3e-10 38.4 0.0 1.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMC83426.1 - 0.01 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Creb_binding PF09030.5 EMC83427.1 - 0.15 12.2 0.1 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Creb binding FlxA PF14282.1 EMC83427.1 - 1.2 9.1 3.5 0.38 10.7 0.4 1.6 2 0 0 2 2 2 0 FlxA-like protein XK-related PF09815.4 EMC83428.1 - 3e-102 342.0 22.6 3.4e-102 341.8 15.6 1.0 1 0 0 1 1 1 1 XK-related protein Prefoldin_2 PF01920.15 EMC83429.1 - 2.4e-07 30.4 0.1 3.1e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EMC83429.1 - 0.048 13.2 0.3 0.062 12.9 0.2 1.1 1 0 0 1 1 1 0 Prefoldin subunit Ribosomal_L29 PF00831.18 EMC83429.1 - 0.061 13.0 3.0 0.11 12.2 2.1 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein NUDE_C PF04880.8 EMC83429.1 - 0.12 12.7 0.1 0.13 12.6 0.1 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TPX2 PF06886.6 EMC83429.1 - 0.48 10.5 3.1 0.72 9.9 2.2 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) IFP_35_N PF07334.8 EMC83429.1 - 0.81 9.7 3.3 0.93 9.5 2.1 1.4 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DSPc PF00782.15 EMC83430.1 - 3.5e-33 114.0 0.0 4.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC83430.1 - 3.8e-07 30.2 0.0 5.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EMC83430.1 - 6.6e-07 28.9 0.0 8.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC83430.1 - 0.15 12.2 0.9 1.1 9.5 0.3 2.2 2 1 1 3 3 3 0 Tyrosine phosphatase family IRF-3 PF10401.4 EMC83432.1 - 4.9e-60 202.1 0.3 6.8e-60 201.7 0.2 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 EMC83432.1 - 3.7e-47 158.6 0.9 6.6e-47 157.8 0.6 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Pkinase PF00069.20 EMC83433.1 - 2.9e-38 131.5 0.0 5e-37 127.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83433.1 - 1.5e-22 79.9 0.0 2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC83433.1 - 0.00041 19.4 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC83433.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC83433.1 - 0.05 12.5 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EMC83433.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 RIO1 family TPX2_importin PF12214.3 EMC83434.1 - 4.8e-59 199.3 64.0 2e-58 197.3 7.8 5.9 3 2 2 6 6 6 3 Cell cycle regulated microtubule associated protein Aurora-A_bind PF09041.5 EMC83434.1 - 1.4e-22 79.1 0.2 5.5e-22 77.3 0.2 2.1 1 0 0 1 1 1 1 Aurora-A binding TPX2 PF06886.6 EMC83434.1 - 2.5e-16 59.4 16.1 2.5e-16 59.4 11.2 7.1 8 0 0 8 8 8 1 Targeting protein for Xklp2 (TPX2) Bcl-2 PF00452.14 EMC83435.1 - 1.4e-33 115.0 0.0 2.2e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.12 EMC83435.1 - 1.2e-14 53.3 0.2 1.9e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.1 EMC83435.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like LBP_BPI_CETP_C PF02886.12 EMC83436.1 - 9.7e-28 96.9 0.0 1.2e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Peptidase_A22B PF04258.8 EMC83437.1 - 6.2e-98 327.9 8.8 7.2e-98 327.7 6.1 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EMC83437.1 - 0.00039 19.6 7.7 0.00077 18.6 5.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) Presenilin PF01080.12 EMC83437.1 - 0.0024 16.7 1.3 0.0039 16.0 0.9 1.4 1 0 0 1 1 1 1 Presenilin DUF4345 PF14248.1 EMC83437.1 - 0.033 13.6 0.2 0.033 13.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Ras PF00071.17 EMC83438.1 - 1.8e-29 102.2 0.0 5.9e-29 100.5 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC83438.1 - 1.2e-14 54.7 0.0 3.1e-14 53.4 0.0 1.7 2 1 0 2 2 1 1 Miro-like protein FeoB_N PF02421.13 EMC83438.1 - 3.1e-05 23.3 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA PF00004.24 EMC83438.1 - 0.0023 18.1 0.1 0.038 14.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC83438.1 - 0.0024 17.8 2.9 0.044 13.7 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EMC83438.1 - 0.0061 16.1 0.0 0.023 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMC83438.1 - 0.008 16.3 0.6 0.46 10.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EMC83438.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMC83438.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EMC83438.1 - 0.027 14.7 0.0 0.065 13.5 0.0 1.6 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 EMC83438.1 - 0.047 13.6 0.0 0.16 11.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 EMC83438.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMC83438.1 - 0.076 13.3 0.8 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMC83438.1 - 0.084 12.2 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EMC83438.1 - 0.092 12.6 0.1 0.2 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC83438.1 - 0.099 12.2 0.1 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EMC83438.1 - 0.75 9.5 3.1 0.8 9.5 0.4 2.3 2 1 0 2 2 2 0 Part of AAA domain DUF4618 PF15397.1 EMC83439.1 - 1.5e-43 148.9 23.1 1.9e-41 142.1 16.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Spc7 PF08317.6 EMC83439.1 - 5.2e-05 22.0 7.6 5.2e-05 22.0 5.3 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein Bacillus_HBL PF05791.6 EMC83439.1 - 0.0032 16.8 2.0 0.0032 16.8 1.4 3.0 2 1 1 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) OmpH PF03938.9 EMC83439.1 - 0.0055 16.6 21.2 0.0055 16.6 14.7 2.0 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Prefoldin PF02996.12 EMC83439.1 - 0.0064 16.1 2.3 0.0064 16.1 1.6 3.6 3 1 1 4 4 4 1 Prefoldin subunit Prefoldin_2 PF01920.15 EMC83439.1 - 0.0089 15.7 6.7 0.0089 15.7 4.6 3.3 2 1 1 3 3 3 1 Prefoldin subunit KxDL PF10241.4 EMC83439.1 - 0.013 15.4 4.7 0.013 15.4 3.3 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein ATG16 PF08614.6 EMC83439.1 - 0.058 13.2 23.7 2.1 8.1 8.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_C97 PF05903.9 EMC83439.1 - 0.082 12.6 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Syntaxin-6_N PF09177.6 EMC83439.1 - 0.35 11.3 13.6 0.24 11.8 4.3 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 EMC83439.1 - 0.56 10.1 10.2 1.7 8.5 0.1 3.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DDE_Tnp_IS66 PF03050.9 EMC83439.1 - 0.71 9.0 8.0 0.17 11.1 1.0 2.2 1 1 1 2 2 2 0 Transposase IS66 family SATase_N PF06426.9 EMC83439.1 - 0.89 9.8 4.7 0.35 11.1 0.5 2.4 2 2 1 3 3 2 0 Serine acetyltransferase, N-terminal AAA_13 PF13166.1 EMC83439.1 - 0.9 7.9 17.0 1.2 7.5 11.8 1.1 1 0 0 1 1 1 0 AAA domain Med9 PF07544.8 EMC83439.1 - 1.1 9.0 16.9 0.87 9.3 0.1 3.2 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4411 PF14367.1 EMC83439.1 - 1.2 8.7 5.9 0.57 9.8 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) Baculo_PEP_C PF04513.7 EMC83439.1 - 2.3 8.0 9.6 0.19 11.5 2.2 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EMC83439.1 - 2.4 7.0 21.6 13 4.6 15.0 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2703 PF10865.3 EMC83439.1 - 2.8 7.8 6.5 1.1 9.2 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) TMF_DNA_bd PF12329.3 EMC83439.1 - 2.9 7.7 24.2 0.82 9.5 4.9 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 EMC83439.1 - 3 7.9 20.9 0.73 9.9 6.5 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EMC83439.1 - 3.1 7.6 14.1 0.76 9.5 3.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3782 PF12644.2 EMC83439.1 - 3.2 7.6 6.0 1.2 8.9 1.6 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF3782) DUF4298 PF14131.1 EMC83439.1 - 3.4 7.6 9.2 0.51 10.2 0.6 2.9 2 1 2 4 4 3 0 Domain of unknown function (DUF4298) Flg_hook PF02120.11 EMC83439.1 - 3.5 7.3 11.9 0.25 11.0 2.2 2.9 3 2 0 3 3 3 0 Flagellar hook-length control protein FliK Vfa1 PF08432.5 EMC83439.1 - 3.7 7.5 8.4 4.7 7.2 5.4 1.5 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPV_P10 PF05531.7 EMC83439.1 - 4.5 7.5 10.8 0.37 11.0 2.8 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.13 EMC83439.1 - 4.6 7.0 8.3 6 6.6 4.7 2.0 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Laminin_II PF06009.7 EMC83439.1 - 5.2 6.8 19.0 0.8 9.4 2.1 2.5 2 1 0 2 2 2 0 Laminin Domain II Fzo_mitofusin PF04799.8 EMC83439.1 - 5.8 6.2 10.3 1.9 7.8 1.9 2.5 2 1 0 2 2 2 0 fzo-like conserved region DUF479 PF04336.7 EMC83439.1 - 6.4 6.9 9.8 0.76 9.9 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF479 AATF-Che1 PF13339.1 EMC83439.1 - 7.5 6.7 13.0 22 5.2 8.9 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF904 PF06005.7 EMC83439.1 - 8 6.8 24.7 62 3.9 10.0 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF1598 PF07643.6 EMC83439.1 - 8.7 6.4 6.6 33 4.5 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1598) RabGAP-TBC PF00566.13 EMC83440.1 - 7.2e-33 113.8 0.0 1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EMC83441.1 - 5.3e-66 222.4 0.3 6.4e-66 222.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83441.1 - 3.5e-21 75.4 0.0 4.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC83441.1 - 6.4e-08 32.6 0.0 1.8e-05 24.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC83441.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMC83441.1 - 0.0048 16.4 1.6 0.0056 16.2 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EMC83441.1 - 0.073 12.0 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like zf-C2H2 PF00096.21 EMC83442.1 - 1.6e-27 94.1 29.8 3.4e-06 27.0 0.7 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC83442.1 - 1.1e-23 82.2 24.4 1.5e-07 31.3 0.1 5.6 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMC83442.1 - 4.3e-19 67.7 21.3 6.3e-05 22.7 0.4 5.6 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMC83442.1 - 6.5e-19 66.8 27.7 0.00014 21.9 0.3 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83442.1 - 2e-10 40.4 24.0 0.0025 17.8 0.2 5.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC83442.1 - 3.3e-06 27.1 22.0 0.03 14.5 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC83442.1 - 8.7e-05 22.5 20.9 0.0016 18.4 2.2 3.9 1 1 3 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 EMC83442.1 - 0.00084 18.9 17.5 1.1 8.9 1.6 5.6 6 0 0 6 6 6 1 XPA protein N-terminal zf-ribbon_3 PF13248.1 EMC83442.1 - 0.0071 15.5 2.8 0.0071 15.5 1.9 4.2 3 1 1 4 4 4 2 zinc-ribbon domain DZR PF12773.2 EMC83442.1 - 0.0088 15.8 15.6 4.6 7.1 6.3 3.6 1 1 1 2 2 2 0 Double zinc ribbon zf-BED PF02892.10 EMC83442.1 - 0.013 15.2 28.0 0.089 12.5 0.4 5.2 2 1 2 4 4 4 0 BED zinc finger Zn-ribbon_8 PF09723.5 EMC83442.1 - 0.014 15.3 22.9 4.9 7.1 0.2 5.2 4 1 0 5 5 5 0 Zinc ribbon domain UPF0547 PF10571.4 EMC83442.1 - 0.017 14.7 17.4 1.7 8.4 0.0 5.1 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 zf-C2H2_2 PF12756.2 EMC83442.1 - 0.022 14.8 22.0 2.7 8.1 0.2 4.7 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Prok-RING_1 PF14446.1 EMC83442.1 - 0.083 12.6 14.8 12 5.7 0.1 5.2 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 HypA PF01155.14 EMC83442.1 - 0.15 11.7 14.6 1.6 8.4 1.7 3.3 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 EMC83442.1 - 0.17 11.8 26.0 0.25 11.2 2.6 3.9 1 1 1 2 2 2 0 FYVE zinc finger zf-LYAR PF08790.6 EMC83442.1 - 0.17 11.6 7.8 10 5.9 0.1 4.0 4 0 0 4 4 3 0 LYAR-type C2HC zinc finger Rpr2 PF04032.11 EMC83442.1 - 0.23 11.3 13.2 0.38 10.6 0.7 2.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_4 PF07975.7 EMC83442.1 - 0.26 11.3 17.3 1.1 9.3 2.7 3.9 2 2 2 4 4 4 0 TFIIH C1-like domain Elf1 PF05129.8 EMC83442.1 - 0.31 10.7 14.8 1.8 8.3 1.6 3.2 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-RING_3 PF14369.1 EMC83442.1 - 0.57 10.2 9.3 25 4.9 0.0 4.4 5 0 0 5 5 4 0 zinc-finger zf-C2HC_2 PF13913.1 EMC83442.1 - 0.62 9.8 21.5 5.5 6.7 0.3 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.1 EMC83442.1 - 0.77 9.3 20.6 0.77 9.3 2.9 4.6 4 1 0 4 4 4 0 zinc-ribbon domain zf-AN1 PF01428.11 EMC83442.1 - 0.79 9.6 20.8 8.3 6.3 0.3 5.5 6 0 0 6 6 5 0 AN1-like Zinc finger DUF329 PF03884.9 EMC83442.1 - 1 8.9 13.4 2.3 7.8 0.1 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF329) Zn_Tnp_IS1595 PF12760.2 EMC83442.1 - 1.4 8.8 28.0 3 7.7 2.3 4.0 1 1 3 4 4 4 0 Transposase zinc-ribbon domain DUF2310 PF10071.4 EMC83442.1 - 1.4 7.8 9.3 0.46 9.4 0.1 2.9 2 1 1 3 3 3 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) zinc_ribbon_5 PF13719.1 EMC83442.1 - 3 7.5 21.0 6 6.5 0.1 5.1 5 0 0 5 5 5 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 EMC83442.1 - 3.1 7.5 13.0 25 4.6 0.1 4.8 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.1 EMC83442.1 - 3.4 7.4 20.7 7.9 6.2 0.1 5.1 5 0 0 5 5 5 0 zinc-ribbon domain CpXC PF14353.1 EMC83442.1 - 3.6 7.5 18.7 2.8 7.9 0.1 4.5 2 2 2 4 4 4 0 CpXC protein SprT-like PF10263.4 EMC83442.1 - 4 7.0 18.6 4.7 6.8 5.2 2.6 1 1 1 2 2 2 0 SprT-like family ADK_lid PF05191.9 EMC83442.1 - 6.3 6.5 21.2 0.31 10.7 0.2 4.4 4 1 0 4 4 4 0 Adenylate kinase, active site lid FYDLN_acid PF09538.5 EMC83442.1 - 7.8 7.1 8.1 23 5.6 0.1 3.6 2 1 1 4 4 3 0 Protein of unknown function (FYDLN_acid) zf-ISL3 PF14690.1 EMC83442.1 - 8.6 6.4 18.3 7.8 6.6 0.2 5.1 6 0 0 6 6 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 YhfH PF14149.1 EMC83442.1 - 8.8 6.2 15.6 38 4.1 0.0 5.0 5 0 0 5 5 5 0 YhfH-like protein DUF1011 PF06237.7 EMC83443.1 - 1.6e-40 137.1 7.7 1.6e-40 137.1 5.4 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1011) DUF983 PF06170.7 EMC83443.1 - 6.1 7.0 16.0 0.11 12.6 1.4 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF983) TSP_1 PF00090.14 EMC83444.1 - 0.00015 21.7 11.1 0.00015 21.7 7.7 2.6 2 1 0 3 3 3 1 Thrombospondin type 1 domain PI31_Prot_N PF11566.3 EMC83445.1 - 6.4e-19 68.0 0.0 8.3e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EMC83445.1 - 4.9e-09 36.7 16.8 1.3e-08 35.3 11.6 1.9 1 1 0 1 1 1 1 PI31 proteasome regulator Syntaphilin PF15290.1 EMC83447.1 - 8.2e-128 426.1 0.5 1.8e-127 425.0 0.4 1.5 1 1 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp IncA PF04156.9 EMC83447.1 - 0.0018 17.9 5.5 0.0029 17.2 3.8 1.3 1 0 0 1 1 1 1 IncA protein Spc7 PF08317.6 EMC83447.1 - 0.036 12.7 8.0 0.059 12.0 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 EMC83447.1 - 0.069 10.4 7.9 0.092 10.0 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec8_exocyst PF04048.9 EMC83447.1 - 0.081 12.5 8.6 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4200 PF13863.1 EMC83447.1 - 0.085 12.8 13.2 0.034 14.0 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.7 EMC83447.1 - 0.26 11.0 3.9 0.43 10.3 2.7 1.3 1 0 0 1 1 1 0 Laminin Domain II AAA_13 PF13166.1 EMC83447.1 - 0.32 9.4 6.2 0.43 8.9 4.3 1.1 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 EMC83447.1 - 0.36 11.5 5.8 0.7 10.6 4.0 1.5 1 0 0 1 1 1 0 Occludin homology domain Lebercilin PF15619.1 EMC83447.1 - 0.89 8.9 14.9 2.1 7.7 10.4 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF342 PF03961.8 EMC83447.1 - 1.1 7.5 6.2 1.5 7.1 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MAD PF05557.8 EMC83447.1 - 1.3 6.9 13.7 1.8 6.5 9.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.6 EMC83447.1 - 1.3 8.9 4.5 2.2 8.2 1.2 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EMC83447.1 - 2.5 7.8 13.1 16 5.2 9.1 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.6 EMC83447.1 - 3.3 7.5 13.5 2.5 7.9 0.9 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 EMC83447.1 - 3.8 5.2 4.5 5.3 4.7 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 EMC83447.1 - 5.6 7.4 7.9 2.3 8.7 1.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mto2_bdg PF12808.2 EMC83447.1 - 6.5 6.9 9.2 1.2 9.3 1.6 3.0 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PDZ PF00595.19 EMC83448.1 - 6.2e-21 74.3 5.1 3e-12 46.5 0.0 2.7 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC83448.1 - 3.9e-10 39.4 0.8 2.3e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 EMC83448.1 - 0.00055 19.6 0.2 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain FKBP_C PF00254.23 EMC83449.1 - 4.4e-28 97.1 0.0 4.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MFS_2 PF13347.1 EMC83450.1 - 7.2e-80 268.4 23.1 8.9e-80 268.1 16.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 EMC83450.1 - 0.16 10.6 39.2 0.0055 15.4 22.2 2.1 2 1 0 2 2 2 0 Major Facilitator Superfamily SEP PF08059.8 EMC83451.1 - 3e-28 97.9 0.3 6.2e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EMC83451.1 - 6.3e-20 71.0 0.1 1.2e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 EMC83451.1 - 0.032 13.5 0.0 0.12 11.6 0.0 2.0 1 1 0 1 1 1 0 Spt20 family C1-set PF07654.10 EMC83452.1 - 5.7e-33 112.7 2.3 1.7e-16 59.9 0.3 3.7 3 2 1 4 4 4 2 Immunoglobulin C1-set domain V-set PF07686.12 EMC83452.1 - 1.6e-21 76.3 0.2 1.1e-14 54.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC83452.1 - 3.3e-20 71.9 1.3 4.6e-07 29.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 EMC83452.1 - 3.3e-20 71.7 0.9 3.9e-10 39.4 0.1 3.3 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC83452.1 - 4.4e-20 71.3 0.2 9.5e-09 35.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83452.1 - 6.5e-16 58.5 6.4 1.6e-05 25.3 0.1 3.8 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 EMC83452.1 - 7.5e-14 51.6 9.1 1e-06 28.7 0.6 4.6 4 1 0 4 4 4 2 Immunoglobulin domain PilZ PF07238.9 EMC83452.1 - 0.0066 16.4 0.4 1.5 8.8 0.1 3.3 2 1 1 3 3 3 1 PilZ domain C2-set PF05790.10 EMC83452.1 - 0.029 14.3 0.2 0.21 11.5 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Marek_A PF02124.10 EMC83452.1 - 0.062 12.7 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Marek's disease glycoprotein A Pilin PF00114.14 EMC83452.1 - 0.1 13.3 0.3 1.1 9.9 0.0 2.6 2 2 1 3 3 3 0 Pilin (bacterial filament) V-set PF07686.12 EMC83453.1 - 1.2e-16 60.6 0.0 1.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC83453.1 - 9.3e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC83453.1 - 5.8e-09 36.3 0.5 2.3e-08 34.4 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 EMC83453.1 - 7.4e-08 32.4 0.9 7.4e-08 32.4 0.6 2.4 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 EMC83453.1 - 1.3e-07 31.6 0.0 2.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Adeno_E3_CR2 PF02439.10 EMC83453.1 - 0.0082 15.6 0.3 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 C2-set_2 PF08205.7 EMC83453.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF4578 PF15147.1 EMC83453.1 - 0.097 13.0 0.0 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) LST1 PF05083.8 EMC83453.1 - 0.14 12.1 1.2 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 LST-1 protein Tweety PF04906.8 EMC83453.1 - 0.14 10.5 0.1 0.18 10.1 0.1 1.1 1 0 0 1 1 1 0 Tweety C1-set PF07654.10 EMC83454.1 - 1.7e-33 114.4 1.4 3.1e-16 59.1 0.2 3.7 3 2 1 4 4 4 3 Immunoglobulin C1-set domain V-set PF07686.12 EMC83454.1 - 5.4e-21 74.6 0.2 9.8e-15 54.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC83454.1 - 6.6e-21 74.0 0.8 2.5e-10 40.1 0.0 3.2 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC83454.1 - 2.5e-19 68.8 0.2 1.2e-08 34.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83454.1 - 3.2e-19 68.8 1.4 3.1e-07 30.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC83454.1 - 6.2e-16 58.6 7.8 2.6e-07 31.0 0.2 3.6 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC83454.1 - 1e-11 44.8 9.7 5.2e-06 26.4 0.8 4.2 3 1 0 3 3 3 2 Immunoglobulin domain Marek_A PF02124.10 EMC83454.1 - 0.062 12.7 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Marek's disease glycoprotein A PilZ PF07238.9 EMC83454.1 - 0.079 12.9 0.3 8.4 6.4 0.1 3.0 3 1 0 3 3 3 0 PilZ domain tRNA_anti-codon PF01336.20 EMC83454.1 - 0.092 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Opiods_neuropep PF01160.13 EMC83455.1 - 4e-14 52.0 5.2 6e-14 51.5 3.6 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide DUF2786 PF10979.3 EMC83455.1 - 0.065 12.9 0.4 0.065 12.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Op_neuropeptide PF08035.6 EMC83455.1 - 0.2 11.2 13.0 0.98 9.0 0.1 4.2 5 0 0 5 5 5 0 Opioids neuropeptide fn3 PF00041.16 EMC83457.1 - 0.00035 20.6 0.1 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain ATS PF15445.1 EMC83457.1 - 0.035 13.2 0.8 0.046 12.8 0.6 1.1 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 IZUMO PF15005.1 EMC83457.1 - 0.48 10.4 6.2 0.4 10.7 3.3 1.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion AAA_11 PF13086.1 EMC83458.1 - 6e-75 251.8 1.2 6.3e-49 166.6 0.1 4.4 3 1 0 3 3 3 2 AAA domain AAA_12 PF13087.1 EMC83458.1 - 3e-69 232.4 0.3 1.5e-43 148.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNB PF00773.14 EMC83458.1 - 1.3e-56 192.3 0.1 3.9e-56 190.7 0.1 1.9 1 1 0 1 1 1 1 RNB domain AAA_19 PF13245.1 EMC83458.1 - 6.9e-17 60.9 0.0 1.3e-07 31.2 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 EMC83458.1 - 1.4e-15 57.3 0.0 0.0035 16.9 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_22 PF13401.1 EMC83458.1 - 3.3e-07 30.5 0.0 0.025 14.7 0.0 4.6 5 1 0 5 5 4 2 AAA domain UvrD_C_2 PF13538.1 EMC83458.1 - 1e-06 28.8 0.1 0.00014 21.9 0.0 2.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EMC83458.1 - 2.3e-06 27.0 0.2 0.94 8.6 0.0 4.2 4 0 0 4 4 4 2 PhoH-like protein UvrD-helicase PF00580.16 EMC83458.1 - 3e-06 26.7 0.0 0.0019 17.5 0.0 3.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EMC83458.1 - 1.6e-05 24.8 0.0 0.21 11.4 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit UvrD_C PF13361.1 EMC83458.1 - 5.6e-05 22.7 0.0 0.21 10.9 0.0 3.3 3 1 0 3 3 3 2 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 EMC83458.1 - 0.00025 20.1 0.0 0.0038 16.2 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EMC83458.1 - 0.00095 19.1 0.0 2.5 8.0 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain T2SE PF00437.15 EMC83458.1 - 0.00098 18.0 0.1 0.27 10.1 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 EMC83458.1 - 0.0018 18.4 0.0 3.4 7.8 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EMC83458.1 - 0.019 14.4 0.1 7.6 5.9 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.1 EMC83458.1 - 0.051 13.1 0.6 7.6 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EMC83458.1 - 0.056 13.1 0.0 14 5.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.9 EMC83458.1 - 0.12 11.9 0.0 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 Helicase SAND PF01342.16 EMC83459.1 - 4.6e-36 122.3 0.0 8.8e-36 121.4 0.0 1.4 1 0 0 1 1 1 1 SAND domain IncA PF04156.9 EMC83459.1 - 0.0077 15.8 0.9 0.012 15.1 0.6 1.3 1 0 0 1 1 1 1 IncA protein Spc7 PF08317.6 EMC83459.1 - 0.43 9.1 3.1 0.19 10.3 0.2 1.8 3 0 0 3 3 3 0 Spc7 kinetochore protein Stathmin PF00836.14 EMC83460.1 - 4.3e-58 194.9 18.8 5.1e-58 194.6 13.0 1.1 1 0 0 1 1 1 1 Stathmin family Fib_alpha PF08702.5 EMC83460.1 - 2 8.5 5.0 2.8 8.0 3.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Helicase_C_2 PF13307.1 EMC83461.1 - 4.3e-52 176.4 0.0 1.6e-51 174.6 0.0 2.1 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EMC83461.1 - 8.4e-50 168.5 6.3 8.4e-50 168.5 4.3 2.1 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 EMC83461.1 - 2.9e-07 30.1 0.0 3.9e-05 23.2 0.0 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC83461.1 - 2.9e-05 23.9 2.8 0.0025 17.6 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMC83461.1 - 7.6e-05 21.6 0.1 0.0003 19.6 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain TNFR_c6 PF00020.13 EMC83462.1 - 6.4e-15 54.9 28.2 1.5e-08 34.5 6.0 3.1 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 EMC83462.1 - 0.0012 18.3 5.7 0.0012 18.3 3.9 3.4 2 2 1 3 3 3 2 GCC2 and GCC3 hEGF PF12661.2 EMC83462.1 - 2.6 8.2 17.4 3.7 7.8 0.7 4.4 3 0 0 3 3 3 0 Human growth factor-like EGF Arf PF00025.16 EMC83463.1 - 1.9e-46 157.4 0.1 2.5e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC83463.1 - 6e-15 55.0 0.1 7.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83463.1 - 2.7e-13 50.4 0.0 3.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EMC83463.1 - 2.9e-11 42.6 0.1 1.9e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMC83463.1 - 1.4e-10 40.7 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC83463.1 - 1.9e-07 31.0 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC83463.1 - 3.5e-07 29.5 0.0 4.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC83463.1 - 0.0026 17.2 0.1 0.014 14.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EMC83463.1 - 0.012 15.9 0.1 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMC83463.1 - 0.03 14.4 0.0 0.29 11.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMC83463.1 - 0.043 13.5 0.2 0.43 10.2 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EMC83463.1 - 0.092 12.6 0.5 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain G-patch PF01585.18 EMC83464.1 - 1.7e-11 43.7 0.1 3.8e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 G-patch domain PPP4R2 PF09184.6 EMC83464.1 - 0.0053 16.3 11.0 0.0053 16.3 7.6 1.6 2 0 0 2 2 2 1 PPP4R2 zf-CCCH_2 PF14608.1 EMC83464.1 - 2.3 8.3 5.1 5.3 7.2 3.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Tmemb_cc2 PF10267.4 EMC83464.1 - 3.7 6.0 16.6 0.038 12.5 5.7 1.8 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein LIME1 PF15332.1 EMC83465.1 - 0.0076 15.5 0.5 0.052 12.7 0.3 2.2 1 1 0 1 1 1 1 Lck-interacting transmembrane adapter 1 PAG PF15347.1 EMC83465.1 - 0.027 13.5 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched zf-C2H2 PF00096.21 EMC83466.1 - 0.0032 17.7 0.4 0.0086 16.3 0.3 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83466.1 - 0.048 14.0 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger BTB PF00651.26 EMC83467.1 - 1.6e-25 89.2 1.2 2.4e-25 88.6 0.8 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC83467.1 - 8.9e-16 57.3 17.8 1.1e-09 38.1 1.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC83467.1 - 3e-09 36.5 15.8 1.7e-05 24.8 0.8 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3342 PF11822.3 EMC83467.1 - 1.4e-06 27.7 0.3 1.4e-06 27.7 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.21 EMC83467.1 - 3.3e-05 23.9 26.7 5.4e-05 23.2 1.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.2 EMC83467.1 - 0.012 15.8 0.1 0.012 15.8 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC83467.1 - 0.21 11.7 18.5 0.16 12.0 5.8 3.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Rubredoxin PF00301.15 EMC83467.1 - 0.27 11.1 2.7 35 4.3 0.2 3.6 3 0 0 3 3 3 0 Rubredoxin zf-C2H2_jaz PF12171.3 EMC83467.1 - 0.31 11.2 15.0 0.45 10.7 0.0 4.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4428 PF14471.1 EMC83467.1 - 1.4 8.7 7.2 0.14 11.9 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) TPD52 PF04201.10 EMC83468.1 - 2e-48 164.1 4.9 1.7e-47 161.1 3.4 1.9 1 1 0 1 1 1 1 Tumour protein D52 family GOLGA2L5 PF15070.1 EMC83468.1 - 0.031 12.7 0.1 0.038 12.4 0.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 VASP_tetra PF08776.6 EMC83468.1 - 0.14 11.4 1.2 0.59 9.4 0.9 1.9 2 0 0 2 2 2 0 VASP tetramerisation domain DnaJ PF00226.26 EMC83469.1 - 3.9e-27 93.7 2.6 5.9e-27 93.1 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain GP41 PF00517.12 EMC83469.1 - 0.0031 17.0 0.0 0.0061 16.1 0.0 1.4 2 0 0 2 2 2 1 Retroviral envelope protein Sigma70_ner PF04546.8 EMC83469.1 - 0.089 12.3 0.0 0.089 12.3 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region UPRTase PF14681.1 EMC83470.1 - 2.3e-73 245.8 0.0 3.4e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EMC83470.1 - 9.4e-54 181.9 0.0 1.7e-53 181.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EMC83470.1 - 8.9e-07 29.7 0.2 3e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC83470.1 - 0.00014 22.1 0.3 0.00037 20.8 0.2 1.7 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EMC83470.1 - 0.00047 19.8 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CoaE PF01121.15 EMC83470.1 - 0.013 14.8 0.4 0.095 12.0 0.2 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase ABC_tran PF00005.22 EMC83470.1 - 0.035 14.4 0.1 11 6.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EMC83470.1 - 0.036 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMC83470.1 - 0.037 13.1 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pribosyltran PF00156.22 EMC83470.1 - 0.044 13.5 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosyl transferase domain AAA_19 PF13245.1 EMC83470.1 - 0.12 12.1 0.0 9.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain SAM_2 PF07647.12 EMC83473.1 - 3.5e-17 62.0 0.4 5.1e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC83473.1 - 6.3e-09 35.8 0.2 1.2e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC83473.1 - 2.9e-05 23.7 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PRP1_N PF06424.7 EMC83474.1 - 6.5e-39 133.2 8.2 6.5e-39 133.2 5.7 1.8 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EMC83474.1 - 8.3e-33 109.8 21.2 0.0013 19.2 0.0 13.7 6 3 8 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 EMC83474.1 - 6.5e-23 80.8 7.2 4e-06 27.0 0.1 9.6 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC83474.1 - 5.4e-20 71.5 17.6 0.0011 19.6 0.0 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMC83474.1 - 1.3e-10 40.6 2.2 0.084 13.1 0.0 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC83474.1 - 5.5e-10 38.3 12.7 0.07 13.0 0.0 10.1 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC83474.1 - 1.8e-08 33.9 14.7 0.0053 16.3 0.2 7.6 7 3 2 9 9 8 3 TPR repeat TPR_8 PF13181.1 EMC83474.1 - 4.4e-07 29.2 0.2 0.055 13.2 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 EMC83474.1 - 9.5e-07 28.8 4.0 0.047 13.4 0.0 6.0 5 1 1 7 7 7 1 Suppressor of forked protein (Suf) TPR_1 PF00515.23 EMC83474.1 - 2.3e-05 23.7 0.6 0.34 10.6 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC83474.1 - 4.5e-05 23.2 5.7 6 6.8 0.0 6.6 5 1 3 8 8 8 2 Tetratricopeptide repeat OsmC PF02566.14 EMC83474.1 - 0.033 14.3 2.2 13 6.0 0.0 5.1 6 0 0 6 6 6 0 OsmC-like protein TPR_6 PF13174.1 EMC83474.1 - 1.7 9.3 12.4 2.5e+02 2.4 0.0 8.2 13 0 0 13 13 9 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMC83474.1 - 4.6 7.1 12.9 0.21 11.4 0.7 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Sox_C_TAD PF12067.3 EMC83477.1 - 1.8e-78 263.2 10.0 3e-78 262.5 7.0 1.3 1 0 0 1 1 1 1 Sox C-terminal transactivation domain HMG_box PF00505.14 EMC83477.1 - 3e-07 30.6 0.6 4.4e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC83477.1 - 0.0038 17.5 0.3 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain TFIIS_M PF07500.9 EMC83478.1 - 3.1e-41 140.0 4.6 3.1e-41 140.0 3.2 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 EMC83478.1 - 1.4e-19 69.3 1.1 4.5e-19 67.7 0.8 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 EMC83478.1 - 1.2e-18 66.3 8.2 2.4e-18 65.4 5.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Phage_XkdX PF09693.5 EMC83478.1 - 0.047 13.2 0.1 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Talin_middle PF09141.5 EMC83478.1 - 0.077 12.6 7.8 1.7 8.3 0.1 3.6 3 1 1 4 4 4 0 Talin, middle domain DBD_Tnp_Mut PF03108.10 EMC83478.1 - 0.078 12.5 1.7 0.13 11.8 0.5 1.9 2 0 0 2 2 2 0 MuDR family transposase DUF3987 PF13148.1 EMC83478.1 - 0.14 10.7 3.0 0.14 10.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TF_Zn_Ribbon PF08271.7 EMC83478.1 - 0.26 10.6 4.6 0.82 9.0 2.8 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Baculo_LEF5_C PF11792.3 EMC83478.1 - 1.5 8.2 4.4 1.7 8.0 1.8 2.0 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Podoplanin PF05808.6 EMC83478.1 - 2.5 7.6 5.9 0.47 9.9 0.3 2.5 2 1 0 2 2 2 0 Podoplanin Ndc1_Nup PF09531.5 EMC83478.1 - 2.8 6.2 5.2 3.2 6.0 3.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RGS PF00615.14 EMC83479.1 - 1.6e-35 121.7 1.2 1.9e-35 121.5 0.8 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain MSG PF02349.10 EMC83479.1 - 0.054 13.4 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Major surface glycoprotein 7tm_1 PF00001.16 EMC83480.1 - 1.2e-64 217.9 18.0 1.7e-64 217.4 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83480.1 - 8.4e-14 51.3 18.9 1.3e-13 50.7 13.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC83480.1 - 3.2e-08 33.0 6.8 3.2e-08 33.0 4.7 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC83480.1 - 4.3e-05 22.7 17.5 4.3e-05 22.7 12.1 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Dispanin PF04505.7 EMC83480.1 - 2 7.9 7.6 0.26 10.8 0.1 3.1 4 0 0 4 4 4 0 Interferon-induced transmembrane protein Herpes_US9 PF06072.6 EMC83480.1 - 6.4 6.6 8.3 0.27 11.0 0.5 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 7tm_1 PF00001.16 EMC83481.1 - 7.3e-56 189.1 24.4 8.4e-56 188.9 16.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83481.1 - 1.4e-14 53.8 21.8 1.8e-14 53.5 15.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC83481.1 - 4.4e-07 29.3 22.4 9.1e-07 28.2 14.6 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv SK_channel PF03530.9 EMC83481.1 - 0.13 12.1 9.3 1.4 8.7 6.4 2.4 1 1 0 1 1 1 0 Calcium-activated SK potassium channel DUF1345 PF07077.6 EMC83481.1 - 2.1 7.8 10.0 0.41 10.1 0.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) zf-C2HC PF01530.13 EMC83482.1 - 1.7e-107 350.6 82.2 1e-16 60.3 3.1 7.5 7 0 0 7 7 7 7 Zinc finger, C2HC type MYT1 PF08474.6 EMC83482.1 - 2.2e-90 302.6 21.5 6.7e-65 219.1 10.7 5.0 3 1 1 4 4 4 2 Myelin transcription factor 1 DUF1664 PF07889.7 EMC83482.1 - 0.55 10.0 3.6 1.4 8.7 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-RING-like PF08746.6 EMC83482.1 - 1 9.3 23.2 2.3 8.2 0.1 7.3 7 0 0 7 7 7 0 RING-like domain PCMT PF01135.14 EMC83483.1 - 1.6e-26 93.1 0.0 2.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EMC83483.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC83483.1 - 0.00022 21.7 0.0 0.00057 20.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EMC83483.1 - 0.00025 20.4 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EMC83483.1 - 0.003 17.9 0.1 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 EMC83483.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SOCS_box PF07525.11 EMC83483.1 - 0.019 14.8 0.0 0.019 14.8 0.0 1.7 2 0 0 2 2 2 0 SOCS box UPF0150 PF03681.10 EMC83483.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) An_peroxidase PF03098.10 EMC83484.1 - 3.4e-186 619.7 0.0 4.5e-186 619.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.11 EMC83484.1 - 3.9e-85 279.8 0.0 6.7e-21 73.9 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83484.1 - 2.6e-54 181.2 0.2 8.3e-14 51.4 0.1 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 EMC83484.1 - 1e-38 131.6 1.9 2.1e-09 37.7 0.8 4.6 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.1 EMC83484.1 - 1.3e-37 127.2 31.3 5.2e-15 54.9 2.8 3.7 1 1 2 3 3 3 3 Leucine rich repeat ig PF00047.20 EMC83484.1 - 1.3e-29 102.0 1.3 5.3e-07 29.6 0.0 4.8 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 EMC83484.1 - 4.4e-29 100.6 0.0 3.1e-07 30.2 0.0 5.2 4 1 0 4 4 4 4 Immunoglobulin V-set domain LRR_4 PF12799.2 EMC83484.1 - 4.8e-21 73.9 15.0 1.4e-07 30.9 0.2 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) C2-set_2 PF08205.7 EMC83484.1 - 1.2e-14 53.9 0.2 0.0043 16.9 0.0 4.5 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain LRR_5 PF13306.1 EMC83484.1 - 1.6e-12 47.2 0.3 4.2e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC83484.1 - 1.4e-06 27.5 20.6 1.1 9.5 0.1 7.3 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_9 PF14580.1 EMC83484.1 - 2e-06 27.4 2.9 0.0039 16.7 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Sp38 PF07354.7 EMC83484.1 - 0.00012 20.7 0.9 0.12 10.9 0.0 3.4 4 0 0 4 4 4 2 Zona-pellucida-binding protein (Sp38) B_lectin PF01453.19 EMC83484.1 - 0.00069 19.4 0.0 7.3 6.5 0.0 3.4 3 0 0 3 3 3 1 D-mannose binding lectin Herpes_gE PF02480.11 EMC83484.1 - 0.037 12.2 0.1 0.18 10.0 0.0 2.1 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E LRR_7 PF13504.1 EMC83484.1 - 0.83 10.1 16.8 17 6.1 0.1 6.5 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 EMC83484.1 - 6.7 7.1 15.3 1.3e+02 3.1 0.0 6.4 5 1 1 6 6 6 0 Leucine Rich repeat Pkinase_Tyr PF07714.12 EMC83485.1 - 3.4e-95 318.0 0.0 4.2e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC83485.1 - 1.4e-52 178.4 0.0 1.9e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC83485.1 - 5.3e-24 83.8 0.0 1.2e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 EMC83485.1 - 1.1e-09 37.7 0.0 2.5e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC83485.1 - 7.5e-07 28.4 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RIO1 PF01163.17 EMC83485.1 - 0.00087 18.6 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EMC83485.1 - 0.0032 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC83485.1 - 0.019 13.9 0.3 0.046 12.7 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_2 PF07653.12 EMC83485.1 - 0.027 13.9 0.0 0.069 12.6 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain APH PF01636.18 EMC83485.1 - 0.053 13.2 0.0 3 7.4 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC83485.1 - 0.18 11.1 0.2 0.69 9.2 0.0 1.8 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL PPDFL PF15060.1 EMC83486.1 - 5.6e-45 151.8 4.7 6.1e-45 151.7 3.3 1.0 1 0 0 1 1 1 1 Differentiation and proliferation regulator GTP_EFTU PF00009.22 EMC83487.1 - 1.2e-57 194.4 0.0 1.7e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC83487.1 - 1.6e-35 121.2 0.0 4.2e-35 119.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC83487.1 - 2.1e-17 63.0 2.1 2.3e-17 62.8 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EMC83487.1 - 4e-05 23.1 0.1 0.00014 21.4 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EMC83487.1 - 0.00051 19.9 0.4 0.0015 18.5 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC83487.1 - 0.024 14.4 0.1 8.6 6.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin family KCNQ_channel PF03520.9 EMC83488.1 - 2.9e-72 242.2 0.0 1.1e-71 240.3 0.0 1.9 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.3 EMC83488.1 - 1.8e-41 140.3 0.9 4.1e-41 139.1 0.6 1.6 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.26 EMC83488.1 - 2.1e-27 95.6 6.7 3.5e-27 94.9 4.6 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EMC83488.1 - 4.5e-13 48.7 3.3 1.3e-12 47.2 2.3 1.8 1 0 0 1 1 1 1 Ion channel Neur_chan_memb PF02932.11 EMC83489.1 - 5.2e-105 350.5 6.2 7.1e-104 346.8 4.3 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC83489.1 - 3.9e-74 248.4 3.8 6.9e-74 247.6 2.6 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF3119 PF11317.3 EMC83489.1 - 0.0039 17.1 2.7 0.014 15.4 1.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) fn3 PF00041.16 EMC83490.1 - 5e-78 257.2 19.2 3e-16 59.3 0.3 6.5 6 0 0 6 6 6 6 Fibronectin type III domain VWA PF00092.23 EMC83490.1 - 7.1e-48 162.6 0.0 1.2e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Collagen PF01391.13 EMC83490.1 - 5.4e-35 118.7 151.4 1.5e-09 37.2 24.5 5.3 3 2 2 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 EMC83490.1 - 1.6e-12 47.8 0.1 9e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain CBM_4_9 PF02018.12 EMC83490.1 - 3.3e-05 23.9 0.2 0.0063 16.5 0.0 3.3 3 0 0 3 3 3 1 Carbohydrate binding domain SusE PF14292.1 EMC83490.1 - 0.0002 21.1 0.4 10 5.9 0.0 5.1 6 1 0 6 6 6 1 SusE outer membrane protein SSI PF00720.12 EMC83490.1 - 0.085 12.7 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Subtilisin inhibitor-like DUF2529 PF10740.4 EMC83490.1 - 0.3 10.5 0.0 0.56 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) DEP PF00610.16 EMC83491.1 - 5.8e-45 150.9 1.0 4.7e-22 77.5 0.1 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.19 EMC83491.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) ArfGap PF01412.13 EMC83492.1 - 9.1e-34 115.7 0.5 9.1e-34 115.7 0.3 3.0 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.8 EMC83492.1 - 0.021 14.8 0.8 0.042 13.8 0.6 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L37ae PF01780.14 EMC83492.1 - 0.052 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 Ribosomal L37ae protein family NKAIN PF05640.9 EMC83493.1 - 1.8e-87 291.4 4.3 2.1e-87 291.2 3.0 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.6 EMC83493.1 - 3.7 7.4 6.2 11 5.9 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) BIR PF00653.16 EMC83494.1 - 1.8e-44 150.0 13.8 1.5e-24 86.1 0.8 3.0 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 EMC83494.1 - 3.1e-15 55.5 8.6 3.1e-15 55.5 5.9 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC83494.1 - 3.8e-06 26.8 8.0 3.8e-06 26.8 5.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC83494.1 - 0.00078 19.1 7.4 0.00078 19.1 5.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC83494.1 - 0.00082 18.9 3.1 0.0042 16.6 2.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EMC83494.1 - 0.00085 18.8 3.1 0.0019 17.6 2.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 GAGA PF09237.6 EMC83494.1 - 0.019 14.5 0.5 0.047 13.2 0.3 1.6 1 0 0 1 1 1 0 GAGA factor DUF2039 PF10217.4 EMC83494.1 - 0.072 13.1 2.0 0.14 12.1 1.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Vps39_2 PF10367.4 EMC83494.1 - 6.8 6.9 8.4 0.65 10.1 1.0 2.4 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 YTH PF04146.10 EMC83495.1 - 5.3e-49 165.4 0.1 7.7e-49 164.8 0.1 1.2 1 0 0 1 1 1 1 YT521-B-like domain HLH PF00010.21 EMC83496.1 - 1.6e-14 53.3 0.4 2.6e-14 52.6 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.11 EMC83497.1 - 4.5e-46 157.1 26.9 4.5e-46 157.1 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EMC83497.1 - 0.57 10.6 2.9 0.58 10.5 0.8 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CLTH PF10607.4 EMC83498.1 - 2.9e-36 124.3 6.1 3.8e-36 123.9 4.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EMC83498.1 - 8.4e-13 47.5 0.4 3.1e-11 42.6 0.1 2.6 2 0 0 2 2 2 1 LisH FlaF PF07309.6 EMC83498.1 - 0.016 15.0 1.5 0.032 14.0 1.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF HLH PF00010.21 EMC83499.1 - 6.7e-09 35.3 0.2 1.3e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Collagen PF01391.13 EMC83500.1 - 4.4e-18 64.5 58.9 2.1e-10 40.0 20.9 2.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) OGFr_N PF04664.8 EMC83501.1 - 2.9e-92 307.8 11.7 4.2e-92 307.2 8.1 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Eaf7 PF07904.8 EMC83502.1 - 3.3e-17 62.2 0.8 5.7e-17 61.4 0.1 1.8 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Asp-B-Hydro_N PF05279.6 EMC83502.1 - 0.062 13.1 5.3 0.073 12.9 3.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4411 PF14367.1 EMC83502.1 - 0.16 11.6 1.0 0.26 10.9 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) RAP1 PF07218.6 EMC83502.1 - 0.73 7.8 4.5 0.88 7.5 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vfa1 PF08432.5 EMC83502.1 - 1.8 8.5 8.9 2.5 8.1 6.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 7tm_1 PF00001.16 EMC83503.1 - 3.8e-12 45.8 18.2 1.6e-11 43.8 12.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC83504.1 - 1.8e-30 105.9 6.1 2e-30 105.8 4.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC83504.1 - 9.4e-05 21.6 5.0 0.00011 21.4 3.5 1.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC83504.1 - 0.00086 18.4 4.4 0.0011 18.2 3.0 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 EMC83504.1 - 0.38 10.5 3.3 0.84 9.3 0.3 2.0 1 1 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa OATP PF03137.15 EMC83505.1 - 1.4e-163 544.8 8.0 2e-163 544.3 5.6 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EMC83505.1 - 3.3e-15 55.6 26.1 3.3e-15 55.6 18.1 3.0 2 2 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.10 EMC83505.1 - 1.2e-08 34.7 6.7 1.2e-08 34.7 4.6 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC83505.1 - 0.02 14.9 8.1 0.066 13.2 5.6 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF1294 PF06961.8 EMC83505.1 - 0.16 11.9 0.6 0.58 10.1 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1294) CtIP_N PF10482.4 EMC83507.1 - 6.1e-54 180.9 18.7 6.1e-54 180.9 12.9 1.7 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain DivIC PF04977.10 EMC83507.1 - 0.01 15.3 9.9 0.087 12.3 0.1 2.9 2 1 0 2 2 2 2 Septum formation initiator DUF904 PF06005.7 EMC83507.1 - 0.047 13.9 22.3 0.095 13.0 5.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF4618 PF15397.1 EMC83507.1 - 0.089 12.1 15.3 0.16 11.3 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.16 EMC83507.1 - 1.2 9.1 17.2 0.45 10.5 0.7 3.4 3 1 1 4 4 4 0 bZIP transcription factor HI0933_like PF03486.9 EMC83507.1 - 1.2 7.4 5.0 1.9 6.8 3.5 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF972 PF06156.8 EMC83507.1 - 3.3 8.0 18.6 7.8 6.8 5.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DivIVA PF05103.8 EMC83507.1 - 3.4 7.7 15.7 1.5 8.8 0.8 2.9 2 1 1 3 3 3 0 DivIVA protein Spc24 PF08286.6 EMC83507.1 - 5.5 6.7 11.2 6.4 6.4 0.8 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cyclin_N PF00134.18 EMC83508.1 - 3.6e-09 36.2 0.5 6.4e-09 35.4 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain HGTP_anticodon PF03129.15 EMC83508.1 - 0.11 12.4 0.0 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Anticodon binding domain Ribosomal_S21e PF01249.13 EMC83509.1 - 4.9e-24 84.0 0.1 5e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Proteasom_Rpn13 PF04683.8 EMC83510.1 - 1.4e-36 124.4 0.1 1.8e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor His_binding PF02098.11 EMC83510.1 - 0.048 13.4 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Tick histamine binding protein 7tm_1 PF00001.16 EMC83511.1 - 4.4e-46 157.1 9.7 6.5e-46 156.5 6.8 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SSXT PF05030.7 EMC83512.1 - 1.3e-34 117.5 2.0 2.7e-34 116.5 1.4 1.5 1 0 0 1 1 1 1 SSXT protein (N-terminal region) DUF1313 PF07011.6 EMC83512.1 - 0.15 11.7 1.8 1.8 8.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1313) FDF PF09532.5 EMC83513.1 - 5.2e-29 100.8 9.8 5.2e-29 100.8 6.8 1.7 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.2 EMC83513.1 - 6e-22 77.2 0.0 1.3e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain Cadherin PF00028.12 EMC83514.1 - 4.1e-70 232.0 4.0 7.4e-22 77.4 0.9 5.7 6 0 0 6 6 6 5 Cadherin domain Cadherin_C PF01049.12 EMC83514.1 - 1.1e-46 158.5 0.6 1.1e-46 158.5 0.4 1.9 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 EMC83514.1 - 1.4e-15 56.8 0.0 3.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Cadherin prodomain like He_PIG PF05345.7 EMC83514.1 - 6.8e-05 22.8 6.9 0.021 14.8 0.2 4.7 5 0 0 5 5 5 1 Putative Ig domain Cadherin_2 PF08266.7 EMC83514.1 - 0.0026 17.2 0.0 8.1 6.0 0.0 3.5 3 0 0 3 3 3 2 Cadherin-like PKD PF00801.15 EMC83514.1 - 0.0075 15.9 1.3 0.49 10.1 0.1 4.1 4 0 0 4 4 4 1 PKD domain Rifin_STEVOR PF02009.11 EMC83514.1 - 0.13 11.8 0.6 0.29 10.7 0.4 1.4 1 0 0 1 1 1 0 Rifin/stevor family DUF3139 PF11337.3 EMC83514.1 - 0.17 12.1 0.2 0.39 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) FAM217 PF15344.1 EMC83515.1 - 1.7e-84 283.0 3.5 1.7e-84 283.0 2.4 2.5 2 1 2 4 4 4 1 FAM217 family CBM_21 PF03370.8 EMC83516.1 - 4.4e-33 113.6 0.3 6.3e-33 113.1 0.2 1.2 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EMC83516.1 - 0.062 13.3 3.2 0.56 10.3 2.2 2.3 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) RhaA PF06134.6 EMC83517.1 - 0.025 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) RPEL PF02755.10 EMC83518.1 - 8.5e-26 88.5 20.6 4.9e-09 35.2 1.9 4.8 4 0 0 4 4 4 4 RPEL repeat Endothelin PF00322.12 EMC83519.1 - 6.5e-05 22.0 3.8 9.8e-05 21.5 2.6 1.3 1 0 0 1 1 1 1 Endothelin family GTPase_binding PF09027.5 EMC83520.1 - 0.14 11.8 0.5 0.32 10.6 0.3 1.6 1 0 0 1 1 1 0 GTPase binding zf-C2H2 PF00096.21 EMC83522.1 - 1.4e-08 34.5 10.7 8.4e-05 22.6 0.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC83522.1 - 1.1e-07 31.8 0.3 1.1e-07 31.8 0.2 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC83522.1 - 2.9e-05 24.0 4.7 0.029 14.5 0.9 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC83522.1 - 0.0025 17.6 0.6 0.0025 17.6 0.4 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 EMC83522.1 - 0.066 13.4 6.4 3.8 7.8 0.8 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ATPase-cat_bd PF12156.3 EMC83522.1 - 0.08 13.4 3.3 0.37 11.3 0.9 2.9 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase RRN7 PF11781.3 EMC83522.1 - 0.14 11.6 1.4 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_4 PF13894.1 EMC83522.1 - 0.3 11.5 9.3 4.5 7.8 0.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger PRELI PF04707.9 EMC83524.1 - 9.1e-56 187.7 0.0 1.1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family ATP-synt_Eps PF04627.8 EMC83525.1 - 2.6e-13 49.3 1.8 2.8e-13 49.1 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Tubulin PF00091.20 EMC83526.1 - 2.1e-72 243.4 0.0 3e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC83526.1 - 1.2e-47 161.0 0.0 2e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMC83526.1 - 9.2e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMC83526.1 - 0.0049 16.3 0.0 0.0098 15.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Peptidase_C1 PF00112.18 EMC83527.1 - 4.4e-51 173.8 11.8 5.5e-51 173.5 8.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EMC83527.1 - 0.066 11.7 0.6 0.13 10.7 0.4 1.4 1 0 0 1 1 1 0 Peptidase C1-like family TH1 PF04858.8 EMC83528.1 - 2.4e-291 967.0 0.4 2.7e-291 966.8 0.3 1.0 1 0 0 1 1 1 1 TH1 protein G-alpha PF00503.15 EMC83529.1 - 3e-104 348.8 1.2 3.4e-104 348.6 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC83529.1 - 1.6e-14 53.5 1.1 1.3e-13 50.5 0.4 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EMC83529.1 - 0.00014 22.3 0.5 0.043 14.3 0.1 2.7 2 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EMC83529.1 - 0.092 12.1 0.1 0.55 9.6 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M17 PF00883.16 EMC83530.1 - 1.6e-93 313.0 0.0 1.9e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain SNARE PF05739.14 EMC83531.1 - 6.8e-18 64.1 4.2 1.4e-17 63.0 0.5 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EMC83531.1 - 1.3e-14 54.1 0.9 1.3e-14 54.1 0.6 2.2 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EMC83531.1 - 0.009 16.0 13.7 0.012 15.6 4.6 2.6 2 2 0 2 2 2 1 Syntaxin-like protein T2SF PF00482.18 EMC83531.1 - 0.017 15.0 2.7 2 8.3 0.1 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF4477 PF14780.1 EMC83531.1 - 0.023 14.1 3.6 0.083 12.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) DUF2116 PF09889.4 EMC83531.1 - 0.026 14.3 1.1 0.058 13.1 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Med11 PF10280.4 EMC83531.1 - 0.027 14.4 4.4 0.033 14.2 0.7 2.3 2 0 0 2 2 2 0 Mediator complex protein DUF3753 PF12575.3 EMC83531.1 - 0.036 13.8 0.4 0.073 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) CCDC-167 PF15188.1 EMC83531.1 - 0.036 13.9 6.5 0.44 10.5 0.1 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 LRRC37AB_C PF14914.1 EMC83531.1 - 0.05 13.0 0.9 0.085 12.2 0.6 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF912 PF06024.7 EMC83531.1 - 0.056 13.5 0.7 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Syntaxin-6_N PF09177.6 EMC83531.1 - 0.075 13.4 9.4 0.27 11.6 1.0 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ODV-E18 PF10717.4 EMC83531.1 - 0.076 12.4 0.4 0.17 11.3 0.3 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ETRAMP PF09716.5 EMC83531.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.6 EMC83531.1 - 0.36 10.6 2.8 0.65 9.8 0.2 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Synaptobrevin PF00957.16 EMC83531.1 - 0.41 10.2 11.4 0.028 14.0 1.5 3.2 3 1 1 4 4 4 0 Synaptobrevin ING PF12998.2 EMC83531.1 - 0.55 10.5 6.4 1.8 8.8 0.1 3.1 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Motile_Sperm PF00635.21 EMC83532.1 - 4.2e-30 103.6 0.2 8.2e-30 102.6 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF904 PF06005.7 EMC83532.1 - 0.0042 17.3 0.2 0.0067 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) IF2_N PF04760.10 EMC83532.1 - 0.059 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF964 PF06133.6 EMC83532.1 - 0.069 13.1 0.5 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF972 PF06156.8 EMC83532.1 - 0.082 13.2 0.3 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) NUDE_C PF04880.8 EMC83532.1 - 0.73 10.1 6.9 0.23 11.7 0.7 2.2 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Ras PF00071.17 EMC83533.1 - 5e-56 188.5 0.0 5.7e-56 188.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83533.1 - 2.1e-20 73.3 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83533.1 - 1.6e-14 53.5 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC83533.1 - 3.8e-06 26.2 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC83533.1 - 1.7e-05 24.3 0.1 5.8e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC83533.1 - 4.9e-05 23.2 0.0 6.7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC83533.1 - 0.00042 20.3 0.0 0.0061 16.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EMC83533.1 - 0.024 13.8 0.0 0.083 12.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CNTF PF01110.12 EMC83533.1 - 0.041 13.1 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor AAA_24 PF13479.1 EMC83533.1 - 0.079 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EMC83533.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) F_actin_cap_B PF01115.12 EMC83533.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit HEAT PF02985.17 EMC83534.1 - 1.1e-23 81.0 18.4 0.011 15.6 0.0 10.7 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.1 EMC83534.1 - 2.2e-13 50.2 0.3 0.00063 19.9 0.0 6.3 3 2 3 6 6 6 3 HEAT repeats AF1Q PF15017.1 EMC83534.1 - 1.1e-06 28.4 0.1 1.1e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Vac14_Fab1_bd PF12755.2 EMC83534.1 - 0.00069 19.9 1.7 5.3 7.5 0.0 5.3 4 3 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC83534.1 - 0.023 15.1 0.8 20 5.8 0.1 4.5 5 0 0 5 5 5 0 HEAT-like repeat LLC1 PF14945.1 EMC83535.1 - 1e-31 109.7 0.4 1.1e-31 109.6 0.3 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein PEPCK PF00821.13 EMC83536.1 - 1.1e-282 938.4 0.0 1.3e-282 938.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF2874 PF11396.3 EMC83536.1 - 0.13 12.2 4.4 24 4.9 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2874) zf-H2C2_2 PF13465.1 EMC83537.1 - 1.8e-32 110.0 63.7 1.7e-06 28.0 0.5 7.6 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 EMC83537.1 - 1.5e-14 53.3 70.1 0.00098 19.3 1.5 9.2 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83537.1 - 1e-12 47.4 61.8 0.0025 18.0 0.4 9.1 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC83537.1 - 2.8e-05 24.0 62.8 0.01 16.0 0.7 9.5 9 1 0 9 9 9 5 C2H2-type zinc-finger domain GAGA PF09237.6 EMC83537.1 - 0.00054 19.4 14.5 0.0062 16.0 0.0 5.1 1 1 5 6 6 6 1 GAGA factor AKAP95 PF04988.7 EMC83537.1 - 0.0017 18.1 0.9 0.0017 18.1 0.6 4.5 4 2 1 5 5 5 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 EMC83537.1 - 0.0025 17.8 44.7 0.25 11.5 0.5 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC83537.1 - 0.013 15.6 0.5 0.013 15.6 0.3 7.8 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC83537.1 - 0.03 14.2 37.8 0.43 10.5 0.1 8.5 9 0 0 9 9 9 0 C2H2-type zinc finger DUF506 PF04720.7 EMC83537.1 - 0.049 13.2 1.0 0.13 11.8 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF506) RRM_6 PF14259.1 EMC83538.1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC83538.1 - 9e-05 22.0 0.0 0.00024 20.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC83538.1 - 0.0003 20.5 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EMC83539.1 - 7.5e-24 82.6 15.2 8e-07 28.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EMC83539.1 - 0.054 11.6 0.4 0.33 9.0 0.3 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 TP6A_N PF04406.9 EMC83540.1 - 9.7e-22 76.4 0.0 1.8e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase TGFb_propeptide PF00688.13 EMC83541.1 - 6.4e-45 153.3 0.0 9.3e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC83541.1 - 5e-44 148.8 1.3 1.1e-43 147.8 0.9 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Rtf2 PF04641.7 EMC83542.1 - 2.5e-80 269.4 11.3 3e-80 269.1 7.8 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EMC83542.1 - 0.086 12.5 1.8 0.43 10.3 1.2 2.3 1 0 0 1 1 1 0 RING-type zinc-finger Branch PF02485.16 EMC83543.1 - 3.5e-51 173.7 1.4 6.7e-51 172.8 0.2 1.8 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Serine_rich PF08824.5 EMC83544.1 - 1.2e-62 210.3 1.5 2e-62 209.6 1.0 1.4 1 0 0 1 1 1 1 Serine rich protein interaction domain DUF3513 PF12026.3 EMC83544.1 - 3.1e-47 160.8 6.2 3.1e-47 160.8 4.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3513) SH3_9 PF14604.1 EMC83544.1 - 2.6e-12 46.1 0.0 4.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC83544.1 - 8.4e-11 41.0 0.0 1.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC83544.1 - 4.6e-09 35.6 0.0 1.1e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain DUF3445 PF11927.3 EMC83544.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) WD40 PF00400.27 EMC83545.1 - 1.3e-37 126.3 9.2 2.4e-10 39.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3312 PF11768.3 EMC83545.1 - 2.7e-05 22.6 0.1 0.00016 20.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Pkinase PF00069.20 EMC83546.1 - 2.6e-70 236.5 0.0 4e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83546.1 - 1.1e-41 142.6 0.0 1.7e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC83546.1 - 3.7e-06 26.1 0.0 1.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC83546.1 - 0.014 15.1 0.1 0.095 12.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC83546.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 EMC83546.1 - 0.027 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EMC83546.1 - 0.067 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1279 PF06916.8 EMC83547.1 - 2e-28 98.5 1.2 2.3e-28 98.2 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) 7tm_1 PF00001.16 EMC83548.1 - 4.5e-41 140.6 37.6 1.9e-39 135.3 26.0 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83548.1 - 5.1e-06 25.8 38.5 1.1e-05 24.7 26.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC83548.1 - 7.9 5.4 43.3 0.064 12.3 18.5 2.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx C1q PF00386.16 EMC83550.1 - 1.8e-09 37.6 0.0 2e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 C1q domain IRS PF02174.12 EMC83551.1 - 1.5e-28 98.2 0.0 3.2e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 EMC83551.1 - 0.026 14.7 0.3 0.055 13.6 0.2 1.5 1 0 0 1 1 1 0 PH domain Prefoldin_2 PF01920.15 EMC83552.1 - 9.1e-25 86.4 8.6 1.1e-24 86.1 5.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 EMC83552.1 - 0.00027 20.7 3.1 0.00045 19.9 2.0 1.4 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EMC83552.1 - 0.00046 20.3 6.2 0.0076 16.4 0.6 2.2 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 EMC83552.1 - 0.00086 19.2 5.0 0.39 10.6 0.2 2.3 2 0 0 2 2 2 2 FlxA-like protein RraB PF06877.6 EMC83552.1 - 0.0017 19.0 2.4 0.016 15.8 0.1 2.3 1 1 1 2 2 2 1 Regulator of ribonuclease activity B Prefoldin PF02996.12 EMC83552.1 - 0.002 17.7 8.5 0.09 12.4 5.9 2.2 1 1 0 1 1 1 1 Prefoldin subunit Med9 PF07544.8 EMC83552.1 - 0.0039 16.8 10.8 0.12 12.1 0.9 2.8 2 1 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 FliD_C PF07195.7 EMC83552.1 - 0.0049 16.1 3.2 0.013 14.8 0.1 2.0 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.5 EMC83552.1 - 0.009 16.1 5.6 0.84 9.7 0.6 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.1 EMC83552.1 - 0.011 15.7 7.7 0.62 10.0 0.4 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIVA PF05103.8 EMC83552.1 - 0.011 15.7 5.9 0.012 15.6 3.2 1.7 1 1 0 1 1 1 0 DivIVA protein DUF4140 PF13600.1 EMC83552.1 - 0.017 15.5 3.1 1.1 9.7 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Lzipper-MIP1 PF14389.1 EMC83552.1 - 0.018 15.1 5.9 0.073 13.1 0.7 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FlgN PF05130.7 EMC83552.1 - 0.023 14.9 1.9 0.031 14.5 1.3 1.2 1 0 0 1 1 1 0 FlgN protein Atg14 PF10186.4 EMC83552.1 - 0.029 13.3 4.5 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GP41 PF00517.12 EMC83552.1 - 0.032 13.8 3.5 0.52 9.8 0.2 2.0 2 0 0 2 2 2 0 Retroviral envelope protein IncA PF04156.9 EMC83552.1 - 0.037 13.6 8.4 0.21 11.1 1.1 2.0 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 EMC83552.1 - 0.039 13.7 5.7 0.086 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EMC83552.1 - 0.04 13.4 5.7 1.2 8.6 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Kinesin-relat_1 PF12711.2 EMC83552.1 - 0.05 14.0 0.9 0.05 14.0 0.7 2.4 2 1 0 2 2 2 0 Kinesin motor TBCA PF02970.11 EMC83552.1 - 0.051 13.6 8.0 0.077 13.0 0.5 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A CCDC-167 PF15188.1 EMC83552.1 - 0.054 13.4 5.6 0.089 12.7 0.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mnd1 PF03962.10 EMC83552.1 - 0.061 12.9 4.5 0.12 11.9 3.0 1.6 1 1 0 1 1 1 0 Mnd1 family GvpL_GvpF PF06386.6 EMC83552.1 - 0.13 11.8 1.2 0.45 10.0 0.8 1.7 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF AAA_23 PF13476.1 EMC83552.1 - 0.14 12.4 6.0 0.19 12.0 4.2 1.2 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 EMC83552.1 - 0.14 11.7 6.5 1.3 8.5 0.4 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 EMC83552.1 - 0.17 11.6 9.4 0.42 10.4 1.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EMC83552.1 - 0.18 11.6 12.7 1.5 8.7 1.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 EMC83552.1 - 0.22 10.7 7.5 0.86 8.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 EMC83552.1 - 0.22 10.6 9.5 1.3 8.1 1.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.8 EMC83552.1 - 0.23 12.2 2.7 6.8 7.4 0.1 2.2 2 0 0 2 2 2 0 Occludin homology domain Tropomyosin_1 PF12718.2 EMC83552.1 - 0.25 11.1 12.2 0.46 10.3 2.4 2.1 2 0 0 2 2 2 0 Tropomyosin like FTA4 PF13093.1 EMC83552.1 - 0.26 10.6 4.6 0.35 10.2 3.0 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Seryl_tRNA_N PF02403.17 EMC83552.1 - 0.27 11.2 8.5 1.4 8.9 1.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 EMC83552.1 - 0.28 11.1 10.9 1 9.3 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AATF-Che1 PF13339.1 EMC83552.1 - 0.29 11.3 4.2 0.56 10.3 0.4 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Fzo_mitofusin PF04799.8 EMC83552.1 - 0.29 10.5 4.3 1.1 8.6 0.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF1732 PF08340.6 EMC83552.1 - 0.3 10.9 4.7 7.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) RNA_pol_Rpb1_5 PF04998.12 EMC83552.1 - 0.3 10.2 2.1 0.37 10.0 1.5 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CtIP_N PF10482.4 EMC83552.1 - 0.41 10.4 5.7 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ADIP PF11559.3 EMC83552.1 - 0.51 10.2 7.9 0.91 9.4 0.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 EMC83552.1 - 0.52 10.1 8.0 1.2 8.9 0.5 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF972 PF06156.8 EMC83552.1 - 0.63 10.4 6.3 1.1 9.5 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 EMC83552.1 - 0.63 8.3 6.7 0.85 7.9 3.4 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Phage_GPO PF05929.6 EMC83552.1 - 0.93 8.6 4.5 6.1 6.0 0.1 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc24 PF08286.6 EMC83552.1 - 1.1 9.0 10.5 3.5 7.3 1.3 2.3 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 CHD5 PF04420.9 EMC83552.1 - 1.3 8.6 3.9 1.5 8.4 0.4 2.0 2 0 0 2 2 2 0 CHD5-like protein Bap31 PF05529.7 EMC83552.1 - 1.3 8.4 9.5 4.4 6.7 0.6 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Spectrin PF00435.16 EMC83552.1 - 1.7 8.9 10.2 1.9 8.8 1.1 2.2 1 1 1 2 2 2 0 Spectrin repeat UPF0449 PF15136.1 EMC83552.1 - 2.2 8.5 6.2 10 6.4 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Med4 PF10018.4 EMC83552.1 - 2.9 7.2 8.7 3.5 6.9 0.8 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Adeno_PIX PF03955.9 EMC83552.1 - 3.9 8.0 5.7 10 6.6 0.7 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF4337 PF14235.1 EMC83552.1 - 4.1 7.2 6.1 6.4 6.5 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Uds1 PF15456.1 EMC83552.1 - 4.8 7.1 7.9 94 3.0 5.5 2.3 1 1 0 1 1 1 0 Up-regulated During Septation SlyX PF04102.7 EMC83552.1 - 5.1 7.5 6.5 20 5.6 0.5 2.5 2 1 0 2 2 2 0 SlyX FlaC_arch PF05377.6 EMC83552.1 - 7.4 6.5 9.0 8.3 6.3 0.7 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.4 EMC83552.1 - 8.3 6.4 9.8 3.2 7.7 0.3 2.4 2 1 0 2 2 2 0 Haemolysin XhlA p450 PF00067.17 EMC83553.1 - 1.4e-88 297.5 0.1 1.5e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PBP1_TM PF14812.1 EMC83554.1 - 0.045 14.0 3.0 0.079 13.2 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OCC1 PF15506.1 EMC83554.1 - 0.13 12.1 0.4 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 OCC1 family Neuromodulin PF06614.6 EMC83554.1 - 0.41 10.5 13.5 0.54 10.1 9.4 1.1 1 0 0 1 1 1 0 Neuromodulin zf-C2H2 PF00096.21 EMC83555.1 - 2.7e-20 71.3 56.7 4.6e-05 23.5 0.7 8.9 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83555.1 - 8.4e-15 53.9 53.4 0.022 15.0 1.0 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC83555.1 - 1.4e-11 44.1 67.4 2.8e-08 33.6 0.2 11.9 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_2 PF12756.2 EMC83555.1 - 1.6e-05 24.9 34.5 0.00018 21.5 1.5 7.0 4 2 1 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMC83555.1 - 0.0053 16.8 29.0 0.12 12.5 0.1 6.1 5 1 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC83555.1 - 0.0056 16.8 49.5 0.19 12.0 2.4 8.4 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 EMC83555.1 - 1.2 8.9 17.1 0.66 9.6 0.6 5.6 5 1 0 5 5 5 0 zinc-finger of a C2HC-type GAGA PF09237.6 EMC83555.1 - 5.3 6.7 8.1 0.98 9.0 0.1 3.1 3 0 0 3 3 3 0 GAGA factor PyrI_C PF02748.10 EMC83555.1 - 7.4 6.0 19.8 1.1 8.6 0.1 5.3 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 EMC83556.1 - 1.4e-09 37.9 26.6 0.0039 17.2 0.2 4.6 3 1 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EMC83556.1 - 2.4e-06 27.4 22.8 0.28 11.5 0.5 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EMC83556.1 - 0.00047 20.2 10.5 0.12 12.6 0.3 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC83556.1 - 0.00056 19.7 22.1 0.68 9.9 0.1 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC83556.1 - 0.00062 19.9 34.6 0.14 12.5 0.6 6.0 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMC83556.1 - 0.059 13.5 0.3 0.059 13.5 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF678 PF05077.7 EMC83556.1 - 1.3 9.0 11.8 1 9.4 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF678) DUF3502 PF12010.3 EMC83557.1 - 0.11 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) E1-E2_ATPase PF00122.15 EMC83558.1 - 4e-19 68.5 0.1 1e-18 67.2 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMC83558.1 - 1.1e-18 68.4 0.0 2.8e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC83558.1 - 7.1e-13 49.1 0.2 2e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC83558.1 - 1.1e-05 25.2 0.0 4.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC83558.1 - 0.003 17.1 0.0 0.012 15.1 0.0 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase GNVR PF13807.1 EMC83558.1 - 0.058 13.1 0.1 0.23 11.2 0.1 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Ion_trans PF00520.26 EMC83559.1 - 1.1e-28 99.8 5.7 6.8e-28 97.2 4.8 1.6 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC83559.1 - 3.7e-27 94.3 0.0 8.9e-27 93.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC83559.1 - 1e-13 50.7 3.1 1e-13 50.7 2.2 2.0 2 0 0 2 2 2 1 Ion channel Glycos_transf_2 PF00535.21 EMC83560.1 - 8.2e-33 113.4 0.0 9.8e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMC83560.1 - 3.5e-10 40.0 0.0 2.1e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMC83560.1 - 1.1e-07 31.2 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMC83560.1 - 9.5e-06 24.9 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EMC83560.1 - 0.041 14.2 0.0 0.079 13.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Homeobox PF00046.24 EMC83561.1 - 2e-07 30.4 0.5 4.7e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain zf-H2C2_5 PF13909.1 EMC83561.1 - 8.9e-05 22.4 0.5 8.9e-05 22.4 0.3 7.2 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EMC83561.1 - 0.004 17.3 49.5 0.02 15.1 0.1 8.7 9 0 0 9 9 9 3 C2H2-type zinc finger Homeobox_KN PF05920.6 EMC83561.1 - 0.0087 15.7 0.3 0.023 14.3 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 EMC83561.1 - 0.08 13.3 0.3 0.08 13.3 0.2 7.4 8 0 0 8 8 8 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 EMC83561.1 - 0.11 12.6 0.2 0.11 12.6 0.1 7.3 7 2 1 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EMC83561.1 - 3.7 7.8 9.8 13 6.0 0.0 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC83561.1 - 8.5 6.5 32.5 0.074 13.1 4.7 6.7 4 3 2 6 6 6 0 C2H2 type zinc-finger (2 copies) PB1 PF00564.19 EMC83562.1 - 1.8e-13 49.9 0.0 3.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.19 EMC83562.1 - 1.8e-11 44.0 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC83562.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF1805 PF08827.6 EMC83563.1 - 0.00038 20.2 0.5 0.0048 16.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1805) HEAT_2 PF13646.1 EMC83563.1 - 0.00093 19.4 4.1 0.0019 18.4 2.0 2.1 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EMC83563.1 - 0.26 11.4 2.2 7.3 6.9 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat DUF4611 PF15387.1 EMC83564.1 - 0.35 11.0 7.0 0.049 13.7 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RP-C_C PF11800.3 EMC83564.1 - 6.4 6.4 8.0 0.6 9.7 1.8 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region eIF-5_eIF-2B PF01873.12 EMC83565.1 - 2.7e-50 169.1 1.2 4.6e-50 168.4 0.8 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cupin_8 PF13621.1 EMC83565.1 - 1.6 8.1 6.0 1.2 8.6 3.0 1.6 2 0 0 2 2 2 0 Cupin-like domain Cytochrom_c3_2 PF14537.1 EMC83565.1 - 8.9 6.7 8.3 0.28 11.5 0.7 2.2 2 1 0 2 2 2 0 Cytochrome c3 7tm_4 PF13853.1 EMC83566.1 - 3.7e-35 120.8 2.9 4.3e-35 120.6 2.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC83566.1 - 0.0065 15.6 0.5 0.0077 15.3 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Trypsin PF00089.21 EMC83567.1 - 2.2e-17 63.4 3.1 2.4e-17 63.2 2.2 1.0 1 0 0 1 1 1 1 Trypsin Bac_surface_Ag PF01103.18 EMC83568.1 - 2.3e-61 208.0 3.7 2.7e-61 207.8 2.5 1.0 1 0 0 1 1 1 1 Surface antigen Surf_Ag_VNR PF07244.10 EMC83568.1 - 0.042 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat CH PF00307.26 EMC83569.1 - 1.4e-24 86.1 2.9 7.2e-12 45.3 0.1 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC83569.1 - 5.1e-05 22.8 0.1 0.014 15.0 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain ACT PF01842.20 EMC83569.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 ACT domain CH PF00307.26 EMC83570.1 - 3.5e-25 88.1 4.8 2.2e-12 46.9 0.1 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC83570.1 - 3.2e-06 26.6 0.7 0.0058 16.2 0.0 3.1 2 1 1 3 3 3 2 CAMSAP CH domain Shisa PF13908.1 EMC83571.1 - 0.037 14.2 22.6 0.41 10.7 15.7 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Acyl_transf_1 PF00698.16 EMC83573.1 - 2.1e-102 342.7 0.0 4.4e-102 341.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EMC83573.1 - 1.1e-74 251.1 0.0 1.9e-74 250.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.15 EMC83573.1 - 1.6e-55 188.8 0.1 4.5e-54 184.0 0.0 2.7 3 0 0 3 3 2 1 Thioesterase domain KR PF08659.5 EMC83573.1 - 1.9e-48 164.5 0.0 2.2e-47 161.0 0.0 2.8 4 0 0 4 4 4 1 KR domain adh_short PF00106.20 EMC83573.1 - 2.2e-46 157.8 0.0 3.4e-45 153.9 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMC83573.1 - 4.8e-37 126.4 0.0 1e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMC83573.1 - 1.9e-20 72.7 0.0 1.9e-20 72.7 0.0 2.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PS-DH PF14765.1 EMC83573.1 - 2e-19 69.8 0.0 4.2e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EMC83573.1 - 2.1e-10 41.6 0.0 9.5e-10 39.4 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMC83573.1 - 6.7e-09 35.8 0.4 1.5e-08 34.7 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EMC83573.1 - 0.00029 19.9 0.0 0.00061 18.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain YjeF_N PF03853.10 EMC83573.1 - 0.0049 16.4 0.1 2.1 7.9 0.0 3.9 4 0 0 4 4 4 1 YjeF-related protein N-terminus ACP_syn_III PF08545.5 EMC83573.1 - 0.013 15.1 0.1 0.068 12.8 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_23 PF13489.1 EMC83573.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EMC83573.1 - 0.099 12.2 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 EMC83574.1 - 3.5e-35 121.3 30.3 3.8e-34 117.9 20.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC83574.1 - 0.00033 20.4 6.7 0.33 10.7 0.0 3.6 3 0 0 3 3 3 2 MFS_1 like family TraB PF01963.12 EMC83577.1 - 7.4e-10 38.7 0.0 8.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 TraB family Neur_chan_LBD PF02931.18 EMC83578.1 - 4.2e-69 232.0 2.7 5.5e-69 231.6 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC83578.1 - 2.8e-59 200.8 0.5 3.6e-59 200.5 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3671 PF12420.3 EMC83578.1 - 9.9 6.1 6.8 4.8 7.1 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF3713 PF12506.3 EMC83579.1 - 0.29 11.2 1.8 0.53 10.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) MFS_1 PF07690.11 EMC83580.1 - 4.4e-26 91.4 28.3 4.4e-26 91.4 19.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMC83580.1 - 4.4e-05 22.0 16.8 4.4e-05 22.0 11.6 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein DUF373 PF04123.8 EMC83580.1 - 3.6 6.5 7.8 0.94 8.4 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF373) zf-C3HC4 PF00097.20 EMC83581.1 - 3.4e-09 36.2 9.3 3.4e-09 36.2 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC83581.1 - 9.2e-09 35.1 8.6 9.2e-09 35.1 5.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC83581.1 - 2.7e-08 33.5 8.6 2.7e-08 33.5 6.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC83581.1 - 4.5e-06 26.2 8.0 4.5e-06 26.2 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC83581.1 - 3.1e-05 23.6 9.3 3.1e-05 23.6 6.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC83581.1 - 0.0014 18.7 6.1 0.0014 18.7 4.2 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC83581.1 - 0.0016 18.2 8.7 0.0016 18.2 6.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC83581.1 - 0.006 16.1 6.2 0.006 16.1 4.3 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain CDC45 PF02724.9 EMC83581.1 - 0.011 13.7 0.1 0.011 13.7 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-Nse PF11789.3 EMC83581.1 - 0.017 14.5 3.9 0.031 13.7 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EMC83581.1 - 0.021 14.5 3.6 0.066 12.9 2.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.6 EMC83581.1 - 0.027 14.0 0.1 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 GAGA factor DUF4512 PF14975.1 EMC83581.1 - 0.053 14.3 0.2 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) BAF1_ABF1 PF04684.8 EMC83581.1 - 0.054 12.3 2.1 0.071 11.9 1.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3337 PF11816.3 EMC83581.1 - 0.29 10.4 6.2 0.86 8.9 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) zf-Apc11 PF12861.2 EMC83581.1 - 0.37 10.6 3.8 0.97 9.3 2.6 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EMC83581.1 - 0.48 10.3 9.1 0.38 10.6 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 EMC83581.1 - 0.89 9.3 7.4 0.35 10.6 3.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Synaphin PF05835.7 EMC83582.1 - 5.9e-29 101.0 10.6 2.4e-28 99.0 7.4 1.7 1 1 0 1 1 1 1 Synaphin protein Stm1_N PF09598.5 EMC83582.1 - 0.089 13.5 2.0 5.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Stm1 Pkinase PF00069.20 EMC83584.1 - 2e-41 141.8 0.0 3.8e-41 140.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83584.1 - 5.8e-27 94.4 0.3 2.2e-21 76.1 0.9 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMC83584.1 - 0.0012 18.6 0.2 0.035 13.8 0.0 2.5 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC83584.1 - 0.11 11.4 0.1 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Enolase_C PF00113.17 EMC83586.1 - 1.4e-27 96.4 0.1 1.6e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain zf-C4 PF00105.13 EMC83588.1 - 4.4e-29 100.5 12.9 7.2e-29 99.8 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC83588.1 - 6.9e-29 100.4 6.2 9.5e-29 99.9 4.3 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RING_2 PF13639.1 EMC83588.1 - 4.9 7.0 8.9 16 5.4 6.2 2.0 1 0 0 1 1 1 0 Ring finger domain Pkinase PF00069.20 EMC83590.1 - 1.1e-71 241.0 0.0 1.6e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.12 EMC83590.1 - 7.8e-45 150.3 0.3 5.9e-23 80.2 0.0 2.7 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.12 EMC83590.1 - 6.7e-32 110.5 0.0 1.1e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC83590.1 - 0.0014 17.6 0.0 0.0033 16.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC83590.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mab-21 PF03281.9 EMC83591.1 - 1.7e-89 299.8 0.0 2.3e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein PP2C PF00481.16 EMC83592.1 - 2.7e-56 190.7 0.3 3.5e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMC83592.1 - 3.2e-15 56.0 0.0 6.1e-15 55.2 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMC83592.1 - 0.00092 18.9 0.4 0.76 9.4 0.1 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Beach PF02138.13 EMC83593.1 - 8.2e-114 379.5 0.1 1.5e-113 378.7 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.16 EMC83593.1 - 3.7e-18 65.1 12.5 8.9e-18 63.9 8.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.1 EMC83593.1 - 1.3e-14 53.9 0.0 4.2e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EMC83593.1 - 9.4e-14 50.6 12.6 3.1e-08 33.1 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EMC83593.1 - 1.8e-06 28.2 0.0 4.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CTP_transf_1 PF01148.15 EMC83594.1 - 1.3e-86 290.4 24.9 1.6e-86 290.1 17.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Homeobox PF00046.24 EMC83595.1 - 3.4e-22 77.8 1.3 5.2e-22 77.2 0.9 1.3 1 0 0 1 1 1 1 Homeobox domain PKK PF12474.3 EMC83595.1 - 0.0085 15.8 2.0 0.014 15.1 1.4 1.3 1 0 0 1 1 1 1 Polo kinase kinase Homez PF11569.3 EMC83595.1 - 0.027 13.5 0.1 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pilt PF15453.1 EMC83595.1 - 0.12 11.9 2.4 0.14 11.8 1.7 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions ABC_trans_N PF14510.1 EMC83595.1 - 0.52 10.4 2.6 0.64 10.1 1.8 1.5 1 1 0 1 1 1 0 ABC-transporter extracellular N-terminal MMtag PF10159.4 EMC83595.1 - 0.52 10.3 5.7 0.82 9.7 4.0 1.5 1 1 0 1 1 1 0 Kinase phosphorylation protein Sulfotransfer_1 PF00685.22 EMC83596.1 - 3.8e-11 42.7 0.1 1.5e-09 37.5 0.0 3.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC83596.1 - 0.00027 21.9 0.0 0.0013 19.6 0.0 2.3 1 0 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.12 EMC83598.1 - 1.8e-79 262.1 9.2 1.3e-16 60.5 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC83598.1 - 5.7e-51 172.4 0.9 5.7e-51 172.4 0.6 2.1 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC83598.1 - 2.2e-07 30.3 0.0 2.8 7.5 0.0 4.7 4 1 0 4 4 4 3 Cadherin-like DUF4131 PF13567.1 EMC83598.1 - 0.016 14.5 0.1 3 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2663 PF10864.3 EMC83598.1 - 0.1 12.8 0.2 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Cadherin PF00028.12 EMC83599.1 - 4.9e-85 279.9 8.4 9.8e-20 70.6 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC83599.1 - 5.4e-56 188.7 0.1 1.1e-55 187.7 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC83599.1 - 6.5e-06 25.6 0.0 1.2 8.7 0.0 4.6 4 1 0 4 4 4 2 Cadherin-like Patched PF02460.13 EMC83600.1 - 9e-67 225.6 11.7 1.2e-66 225.2 8.1 1.0 1 0 0 1 1 1 1 Patched family PsaX PF08078.7 EMC83600.1 - 0.21 11.5 2.6 0.7 9.8 0.4 2.6 3 0 0 3 3 3 0 PsaX family ACR_tran PF00873.14 EMC83600.1 - 0.64 7.3 7.7 0.79 7.0 5.3 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family SecD_SecF PF02355.11 EMC83600.1 - 3.9 6.6 13.2 9.6 5.3 9.2 1.6 1 1 0 1 1 1 0 Protein export membrane protein Peptidase_M41 PF01434.13 EMC83601.1 - 3.1e-75 252.2 2.2 5.5e-75 251.4 1.6 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMC83601.1 - 1.7e-41 141.5 0.0 5.4e-41 139.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC83601.1 - 4.5e-05 23.6 0.0 0.0026 17.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC83601.1 - 9.7e-05 22.4 0.4 0.0032 17.4 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 EMC83601.1 - 0.00011 21.9 0.0 0.00047 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMC83601.1 - 0.0002 22.1 0.0 0.0015 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EMC83601.1 - 0.00025 19.8 0.2 0.00066 18.4 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EMC83601.1 - 0.0003 19.9 0.0 0.00069 18.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMC83601.1 - 0.0013 18.1 0.0 0.004 16.5 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMC83601.1 - 0.0019 17.8 0.2 0.0053 16.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EMC83601.1 - 0.002 17.5 0.3 0.042 13.2 0.2 2.3 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC83601.1 - 0.0041 16.2 0.0 0.011 14.8 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EMC83601.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMC83601.1 - 0.0089 15.2 0.3 0.029 13.5 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EMC83601.1 - 0.012 15.9 0.0 0.048 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 EMC83601.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMC83601.1 - 0.019 13.8 0.0 0.043 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMC83601.1 - 0.026 14.4 0.0 0.082 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMC83601.1 - 0.037 14.0 0.3 0.1 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 EMC83601.1 - 0.097 11.8 0.5 0.3 10.2 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein FumaraseC_C PF10415.4 EMC83601.1 - 0.31 11.1 4.0 1.7 8.7 1.0 3.3 3 0 0 3 3 3 0 Fumarase C C-terminus LRAT PF04970.8 EMC83602.1 - 2.6e-06 27.3 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF4105 PF13387.1 EMC83602.1 - 0.047 12.8 0.6 2.8 7.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) Nanovirus_coat PF04660.7 EMC83602.1 - 0.14 11.8 0.0 1 9.0 0.0 1.9 1 1 1 2 2 2 0 Nanovirus coat protein zf-C3HC4_3 PF13920.1 EMC83603.1 - 6.9e-11 41.6 7.0 1.5e-10 40.5 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC83603.1 - 1.1e-08 34.6 10.3 1.1e-08 34.6 7.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC83603.1 - 1.4e-08 34.2 8.0 1.4e-08 34.2 5.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC83603.1 - 1.5e-07 31.2 9.9 1.5e-07 31.2 6.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC83603.1 - 4.1e-06 26.8 6.7 4.1e-06 26.8 4.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC83603.1 - 6.6e-06 25.7 7.4 1.7e-05 24.4 5.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC83603.1 - 0.0027 17.3 1.8 0.0027 17.3 1.2 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC83603.1 - 0.0036 17.1 7.4 0.0096 15.7 5.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMC83603.1 - 0.0041 16.9 6.8 0.0063 16.3 2.7 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMC83603.1 - 0.03 13.9 3.0 0.03 13.9 2.1 2.6 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 EMC83603.1 - 0.36 10.6 6.6 1.1 9.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) zf-MIZ PF02891.15 EMC83603.1 - 0.37 10.3 9.7 0.66 9.5 0.3 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.1 EMC83603.1 - 3.7 7.1 9.1 28 4.3 6.3 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 I-set PF07679.11 EMC83604.1 - 3.6e-68 225.4 0.0 2e-12 46.8 0.0 7.0 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83604.1 - 8.9e-55 182.7 0.6 7.7e-11 41.9 0.0 6.8 7 0 0 7 7 6 6 Immunoglobulin domain fn3 PF00041.16 EMC83604.1 - 1.9e-54 181.6 4.5 2.9e-13 49.7 0.1 5.7 5 0 0 5 5 5 5 Fibronectin type III domain Ig_3 PF13927.1 EMC83604.1 - 5.2e-42 142.1 1.0 3e-07 30.8 0.0 7.3 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.20 EMC83604.1 - 1.6e-28 98.5 1.3 0.00032 20.7 0.0 7.5 8 0 0 8 8 8 5 Immunoglobulin domain V-set PF07686.12 EMC83604.1 - 2.5e-27 95.0 2.5 4.6e-05 23.2 0.1 7.8 5 3 1 6 6 6 6 Immunoglobulin V-set domain Bravo_FIGEY PF13882.1 EMC83604.1 - 4.2e-27 94.8 4.9 9.3e-27 93.7 3.4 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region C2-set_2 PF08205.7 EMC83604.1 - 8.9e-09 35.1 1.4 0.37 10.7 0.0 6.7 7 1 0 7 7 7 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 EMC83604.1 - 0.00034 20.5 0.3 9.7 6.2 0.0 4.1 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Receptor_2B4 PF11465.3 EMC83604.1 - 0.00043 20.1 0.4 13 5.7 0.0 4.5 3 1 1 4 4 4 1 Natural killer cell receptor 2B4 Herpes_gE PF02480.11 EMC83604.1 - 0.0019 16.5 0.1 2.3 6.3 0.0 3.5 4 1 0 4 4 4 2 Alphaherpesvirus glycoprotein E PolyA_pol PF01743.15 EMC83605.1 - 3.9e-32 111.1 0.3 7.2e-32 110.2 0.2 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EMC83605.1 - 1.6e-11 43.5 0.2 8.9e-11 41.2 0.0 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Myb_DNA-bind_2 PF08914.6 EMC83605.1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Rap1 Myb domain DUF3432 PF11914.3 EMC83606.1 - 2.3e-24 85.2 138.5 0.0097 15.9 9.9 11.2 1 1 6 7 7 7 6 Domain of unknown function (DUF3432) E1-E2_ATPase PF00122.15 EMC83607.1 - 6.4e-49 166.0 0.6 7.3e-49 165.8 0.4 1.0 1 0 0 1 1 1 1 E1-E2 ATPase BATS PF06968.8 EMC83607.1 - 0.12 12.2 0.1 1.5 8.6 0.0 2.6 2 1 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain Collagen PF01391.13 EMC83608.1 - 0.032 13.7 29.3 0.077 12.5 20.3 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) UBN2_2 PF14227.1 EMC83608.1 - 0.04 13.4 0.1 0.059 12.9 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Carn_acyltransf PF00755.15 EMC83609.1 - 2e-210 699.8 0.0 2.4e-210 699.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rubella_Capsid PF05750.6 EMC83610.1 - 0.1 11.9 1.7 0.1 11.9 1.2 1.1 1 0 0 1 1 1 0 Rubella capsid protein TCR PF03638.10 EMC83611.1 - 1.2e-17 63.4 48.0 8.8e-13 47.8 15.9 2.6 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain GMAP PF06540.6 EMC83612.1 - 4.3e-24 84.0 0.1 4.3e-24 84.0 0.0 1.5 2 0 0 2 2 2 1 Galanin message associated peptide (GMAP) Galanin PF01296.13 EMC83612.1 - 6.7e-18 64.2 2.0 1.1e-17 63.4 1.4 1.3 1 0 0 1 1 1 1 Galanin SAPS PF04499.10 EMC83613.1 - 1.4e-102 343.7 10.9 1.2e-62 212.1 5.5 3.8 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein Atx10homo_assoc PF09759.4 EMC83613.1 - 0.21 11.3 2.4 0.78 9.5 0.2 2.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Ldl_recept_b PF00058.12 EMC83614.1 - 2e-154 501.7 51.9 1.7e-13 50.6 0.0 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 EMC83614.1 - 6e-37 125.4 64.9 6.8e-12 45.2 5.2 5.6 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.13 EMC83614.1 - 8.3e-32 108.8 57.5 5.3e-13 48.6 7.7 4.4 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A SGL PF08450.7 EMC83614.1 - 7.7e-19 68.0 23.7 0.019 14.3 0.4 11.5 7 4 4 12 12 12 7 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EMC83614.1 - 1.6e-08 34.3 0.0 9 6.3 0.0 8.2 8 1 1 9 9 9 1 Arylesterase NHL PF01436.16 EMC83614.1 - 3.6e-05 23.5 0.3 8 6.6 0.0 6.8 7 0 0 7 7 7 1 NHL repeat Lactonase PF10282.4 EMC83614.1 - 0.053 12.5 0.0 23 3.9 0.0 4.1 5 0 0 5 5 5 0 Lactonase, 7-bladed beta-propeller Methyltransf_12 PF08242.7 EMC83614.1 - 0.061 13.7 0.5 2.7e+02 2.1 0.0 5.7 6 2 1 7 7 7 0 Methyltransferase domain Trypan_PARP PF05887.6 EMC83615.1 - 0.0035 17.1 3.0 0.0045 16.8 2.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) zf-AN1 PF01428.11 EMC83615.1 - 0.13 12.2 0.1 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AN1-like Zinc finger Exo_endo_phos_2 PF14529.1 EMC83617.1 - 2.8e-08 33.4 0.0 4.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase LRR_6 PF13516.1 EMC83618.1 - 4.3e-36 118.9 57.9 0.00029 20.6 0.1 14.2 14 0 0 14 14 14 12 Leucine Rich repeat LRR_4 PF12799.2 EMC83618.1 - 8.2e-21 73.1 30.2 0.0016 17.9 0.1 8.5 7 2 0 7 7 7 7 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMC83618.1 - 1.6e-10 39.3 42.4 1.5 9.3 0.1 13.4 14 0 0 14 14 14 5 Leucine rich repeat LRR_1 PF00560.28 EMC83618.1 - 2.1e-10 39.1 38.1 1 9.6 0.1 13.2 14 0 0 14 14 14 4 Leucine Rich Repeat LRR_8 PF13855.1 EMC83618.1 - 0.00041 20.0 37.2 0.069 12.9 0.9 8.2 4 3 4 8 8 8 6 Leucine rich repeat Ras PF00071.17 EMC83621.1 - 8.5e-58 194.3 0.0 9.7e-58 194.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83621.1 - 3.6e-20 72.6 0.0 4.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83621.1 - 7.4e-10 38.3 0.0 9e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC83621.1 - 1.7e-07 30.8 0.1 9e-07 28.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC83621.1 - 1.1e-05 25.2 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC83621.1 - 0.0016 17.7 0.0 0.012 14.8 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EMC83621.1 - 0.0021 17.2 0.0 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMC83621.1 - 0.028 13.9 0.4 0.62 9.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMC83621.1 - 0.03 14.4 0.1 0.43 10.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 EMC83621.1 - 0.037 13.4 0.3 0.073 12.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EMC83621.1 - 0.04 12.9 0.0 0.072 12.1 0.0 1.6 1 1 0 1 1 1 0 Septin DUF258 PF03193.11 EMC83621.1 - 0.067 12.3 0.3 0.11 11.6 0.1 1.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EMC83621.1 - 0.11 11.1 0.0 3.7 6.1 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit DUF2075 PF09848.4 EMC83621.1 - 0.13 11.1 0.1 0.83 8.5 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EMC83621.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.2 EMC83622.1 - 1.3e-15 56.5 11.3 1.5e-09 37.2 0.1 3.9 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC83622.1 - 1.4e-10 40.7 21.1 1.1e-05 25.1 0.6 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EMC83622.1 - 0.00012 21.5 13.4 0.96 9.7 0.5 5.7 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EMC83622.1 - 0.00025 20.8 19.2 0.14 12.3 0.2 6.2 4 2 1 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EMC83622.1 - 0.0062 16.5 15.0 1.9 9.0 0.1 5.7 5 1 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 EMC83622.1 - 0.013 15.0 1.4 0.026 14.0 0.4 1.9 1 1 1 2 2 2 0 Leucine-rich repeat PHD PF00628.24 EMC83623.1 - 0.054 13.2 0.3 0.082 12.6 0.2 1.3 1 0 0 1 1 1 0 PHD-finger LRR_8 PF13855.1 EMC83624.1 - 1.8e-25 88.4 21.5 2.8e-13 49.4 1.6 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC83624.1 - 5.6e-23 80.1 15.1 2.3e-08 33.4 0.6 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC83624.1 - 2.9e-19 66.1 13.2 0.016 15.1 0.2 6.1 6 0 0 6 6 6 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC83624.1 - 1.7e-14 51.3 12.2 0.081 13.1 0.5 6.3 6 0 0 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EMC83624.1 - 2.3e-09 36.3 12.6 0.87 9.8 0.0 6.2 6 0 0 6 6 6 4 Leucine Rich repeat LRR_5 PF13306.1 EMC83624.1 - 1e-06 28.4 0.0 0.0016 18.1 0.0 1.8 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC83624.1 - 3.1e-05 23.5 4.5 0.0016 18.0 0.6 2.4 1 1 1 2 2 2 2 Leucine-rich repeat TBCA PF02970.11 EMC83625.1 - 0.16 12.1 1.4 20 5.3 0.4 2.7 1 1 1 2 2 2 0 Tubulin binding cofactor A IRF-3 PF10401.4 EMC83626.1 - 2.1e-47 161.0 0.8 2.4e-47 160.8 0.6 1.0 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 EMC83627.1 - 1.5e-29 101.9 0.1 1.9e-18 66.2 0.0 2.0 2 0 0 2 2 2 2 Interferon regulatory factor transcription factor Mito_carr PF00153.22 EMC83628.1 - 2.1e-64 213.2 2.0 5e-23 80.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NYAP_C PF15452.1 EMC83628.1 - 0.021 13.8 0.2 3.7 6.4 0.0 2.6 3 0 0 3 3 3 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter LRR_4 PF12799.2 EMC83629.1 - 5e-21 73.8 35.3 1.5e-07 30.9 1.5 7.0 1 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC83629.1 - 2.1e-19 69.0 31.7 3.8e-09 36.1 5.0 5.4 2 1 1 5 5 5 4 Leucine rich repeat Death PF00531.17 EMC83629.1 - 3.6e-11 42.6 0.1 1.2e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Death domain LRR_1 PF00560.28 EMC83629.1 - 7.5e-11 40.5 37.0 0.0028 17.4 0.4 9.6 10 0 0 10 10 10 5 Leucine Rich Repeat ZU5 PF00791.15 EMC83629.1 - 1.5e-09 37.4 0.5 2.9e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 ZU5 domain Peptidase_S68 PF10461.4 EMC83629.1 - 7.1e-08 32.0 6.4 2.2e-07 30.4 1.1 2.6 2 0 0 2 2 2 1 Peptidase S68 LRR_7 PF13504.1 EMC83629.1 - 2.5e-06 26.7 34.2 0.54 10.6 0.2 9.9 9 0 0 9 9 9 3 Leucine rich repeat Ribosomal_60s PF00428.14 EMC83630.1 - 5.6e-07 29.8 0.1 6.6e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Patatin PF01734.17 EMC83631.1 - 1.6e-12 47.8 3.8 1.4e-10 41.4 2.6 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase EF-hand_6 PF13405.1 EMC83632.1 - 1.3e-06 27.7 0.0 0.0055 16.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EMC83632.1 - 1.8e-06 27.9 3.6 4e-06 26.8 0.0 3.2 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC83632.1 - 4.1e-06 25.6 0.4 0.036 13.3 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EMC83632.1 - 0.0013 18.3 0.1 0.0046 16.5 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 EMC83632.1 - 0.14 11.8 2.6 0.14 11.8 0.1 2.4 2 0 0 2 2 2 0 EF hand Peptidase_S46 PF10459.4 EMC83632.1 - 9.1 4.5 15.3 15 3.8 10.6 1.3 1 0 0 1 1 1 0 Peptidase S46 Ras PF00071.17 EMC83633.1 - 4.5e-52 175.7 0.3 5e-52 175.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83633.1 - 1.1e-21 77.5 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83633.1 - 1.5e-15 56.9 0.0 1.8e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC83633.1 - 6.2e-11 41.8 0.0 6.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC83633.1 - 1.4e-10 40.9 0.0 4.3e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC83633.1 - 4.4e-08 33.0 0.0 5.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC83633.1 - 0.0013 17.9 0.1 0.0028 16.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMC83633.1 - 0.0031 17.3 0.1 1.2 8.9 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.1 EMC83633.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.9 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 EMC83633.1 - 0.016 14.4 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EMC83633.1 - 0.026 14.3 0.1 0.043 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EMC83633.1 - 0.044 12.8 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_24 PF13479.1 EMC83633.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMC83633.1 - 0.076 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMC83633.1 - 0.081 12.4 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMC83633.1 - 0.082 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EMC83633.1 - 0.12 12.0 0.1 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Tetraspannin PF00335.15 EMC83634.1 - 2.1e-43 148.1 18.6 6.4e-35 120.4 5.2 2.0 1 1 1 2 2 2 2 Tetraspanin family DUF2215 PF10225.4 EMC83634.1 - 0.0028 17.1 0.1 0.0064 15.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2215) DUF2182 PF09948.4 EMC83634.1 - 0.069 13.0 1.8 0.12 12.2 1.2 1.4 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) VitD-bind_III PF09164.5 EMC83634.1 - 0.08 12.5 0.5 0.53 9.9 0.3 2.2 1 1 1 2 2 2 0 Vitamin D binding protein, domain III Pex24p PF06398.6 EMC83634.1 - 0.088 11.5 0.2 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4500 PF14937.1 EMC83634.1 - 0.2 11.4 2.0 12 5.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) zf-DHHC PF01529.15 EMC83634.1 - 0.52 9.6 6.4 0.74 9.1 0.7 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase Baculo_11_kDa PF06143.6 EMC83634.1 - 0.68 9.3 9.8 6.8 6.1 4.5 2.5 2 1 0 2 2 2 0 Baculovirus 11 kDa family Yip1 PF04893.12 EMC83634.1 - 2.8 7.4 15.9 0.63 9.5 8.8 1.4 2 0 0 2 2 2 0 Yip1 domain DUF3592 PF12158.3 EMC83634.1 - 6.2 6.5 6.7 2.6 7.8 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) RNA_pol_N PF01194.12 EMC83635.1 - 1.7e-30 104.7 0.3 1.9e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EMC83635.1 - 0.096 12.7 0.3 0.16 12.0 0.2 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Tetraspannin PF00335.15 EMC83636.1 - 6.6e-46 156.3 18.5 7.5e-46 156.1 12.8 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 EMC83636.1 - 0.0045 16.9 9.6 0.0082 16.0 6.7 1.7 1 1 0 1 1 1 1 CD20-like family Claudin_2 PF13903.1 EMC83636.1 - 0.014 15.0 3.6 0.014 15.0 2.5 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction GP38 PF05268.6 EMC83636.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 DUF2207 PF09972.4 EMC83636.1 - 0.61 8.6 4.1 1.1 7.8 2.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MARVEL PF01284.18 EMC83636.1 - 4.2 7.1 14.1 0.57 10.0 5.7 2.1 2 0 0 2 2 2 0 Membrane-associating domain Glyco_hydro_18 PF00704.23 EMC83637.1 - 3.9e-21 75.8 0.0 4.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Adaptin_N PF01602.15 EMC83638.1 - 1e-145 486.0 4.4 1.3e-145 485.7 3.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EMC83638.1 - 1.8e-44 150.2 0.0 5.1e-44 148.8 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EMC83638.1 - 3.9e-16 59.3 0.2 8.4e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.2 EMC83638.1 - 8e-07 29.0 0.2 0.00045 20.1 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMC83638.1 - 1.8e-05 24.9 3.5 0.0099 16.1 0.1 4.6 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 EMC83638.1 - 0.0017 18.2 2.5 15 6.0 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat RIX1 PF08167.7 EMC83638.1 - 0.01 15.5 0.3 0.55 9.9 0.0 3.1 2 1 0 3 3 3 0 rRNA processing/ribosome biogenesis M11L PF11099.3 EMC83638.1 - 0.029 14.1 1.9 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Apoptosis regulator M11L like AP4E_app_platf PF14807.1 EMC83638.1 - 0.06 13.5 0.7 0.24 11.6 0.0 2.5 3 0 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform Cys_knot PF00007.17 EMC83639.1 - 0.0039 17.2 12.0 0.0079 16.2 8.3 1.6 1 0 0 1 1 1 1 Cystine-knot domain VWD PF00094.20 EMC83640.1 - 1.4e-77 259.3 23.4 4.1e-28 98.5 1.1 4.1 4 0 0 4 4 4 3 von Willebrand factor type D domain C8 PF08742.6 EMC83640.1 - 2.2e-46 155.9 38.5 8.5e-22 77.2 7.8 5.9 7 0 0 7 7 7 3 C8 domain TIL PF01826.12 EMC83640.1 - 2.2e-17 62.8 54.9 6.2e-11 42.2 12.4 9.3 9 2 0 9 9 9 3 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 EMC83640.1 - 1.7e-06 27.9 20.2 1e-05 25.5 2.8 9.7 7 4 1 8 8 8 2 von Willebrand factor type C domain VWD PF00094.20 EMC83641.1 - 1.5e-26 93.4 0.4 2.5e-26 92.7 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 EMC83641.1 - 7.8e-18 64.4 11.1 1.6e-17 63.4 7.7 1.6 1 0 0 1 1 1 1 C8 domain VWD PF00094.20 EMC83642.1 - 1.2e-30 106.7 3.3 1.2e-30 106.7 2.3 2.1 2 1 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 EMC83642.1 - 1.1e-20 73.5 14.3 1.1e-20 73.5 9.9 2.4 3 0 0 3 3 3 1 C8 domain Pacifastin_I PF05375.8 EMC83642.1 - 5.5e-05 22.5 12.7 5.5e-05 22.5 8.8 3.8 2 1 0 2 2 2 1 Pacifastin inhibitor (LCMII) TIL PF01826.12 EMC83642.1 - 0.00095 19.2 6.2 0.00095 19.2 4.3 4.7 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Pkinase PF00069.20 EMC83644.1 - 4.1e-34 117.9 0.0 7e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83644.1 - 7e-20 71.1 0.0 1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.23 EMC83645.1 - 1.5e-86 290.4 0.1 1.8e-86 290.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC83645.1 - 1.5e-20 73.9 0.6 3e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Str_synth PF03088.11 EMC83646.1 - 3.2e-29 100.8 0.2 1.1e-28 99.1 0.0 2.0 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.7 EMC83646.1 - 1.2e-13 50.9 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EMC83646.1 - 0.00035 20.4 0.0 0.05 13.5 0.0 3.1 3 1 0 3 3 3 1 Arylesterase NHL PF01436.16 EMC83646.1 - 0.00068 19.4 0.1 0.092 12.7 0.0 3.9 5 0 0 5 5 5 1 NHL repeat PQQ_2 PF13360.1 EMC83646.1 - 0.0069 15.8 0.0 2.5 7.5 0.0 2.4 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EMC83646.1 - 0.023 14.9 0.1 1.8 8.9 0.0 3.2 3 1 0 3 3 3 0 PQQ-like domain PD40 PF07676.7 EMC83646.1 - 0.037 13.6 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cystatin PF00031.16 EMC83647.1 - 5.3e-20 71.3 0.0 6.2e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain YmzC PF14157.1 EMC83647.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 YmzC-like protein DUF3088 PF11287.3 EMC83648.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) RNA_POL_M_15KD PF02150.11 EMC83648.1 - 0.067 12.8 0.9 0.067 12.8 0.6 1.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Rpr2 PF04032.11 EMC83648.1 - 0.13 12.1 2.3 0.29 11.0 1.6 1.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RRM_5 PF13893.1 EMC83649.1 - 3.9e-39 132.2 7.7 2.2e-16 59.4 0.1 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC83649.1 - 5.2e-25 87.2 0.9 4.7e-12 45.7 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC83649.1 - 1.9e-17 62.6 0.2 4e-07 29.5 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC83649.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 EMC83649.1 - 0.019 14.7 0.0 0.5 10.1 0.0 2.6 3 0 0 3 3 3 0 Limkain b1 Aldose_epim PF01263.15 EMC83650.1 - 1.9e-93 312.8 0.2 2.1e-93 312.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.17 EMC83651.1 - 4.9e-17 61.3 0.0 6.8e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC83651.1 - 2.9e-11 43.1 0.0 4.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC83651.1 - 2.2e-10 40.1 0.0 3.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EMC83651.1 - 0.00035 20.2 2.3 0.00098 18.8 1.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EMC83651.1 - 0.0005 19.8 6.1 0.0011 18.8 4.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Gemin6 PF06372.7 EMC83652.1 - 8.4e-66 220.3 0.6 9.2e-66 220.2 0.4 1.0 1 0 0 1 1 1 1 Gemin6 protein RRM_1 PF00076.17 EMC83653.1 - 1.4e-16 59.8 0.0 1.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC83653.1 - 2.1e-10 40.4 0.0 3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC83653.1 - 2.1e-09 37.1 0.0 3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EMC83653.1 - 0.00044 20.0 6.1 0.00088 19.0 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EMC83653.1 - 0.00081 19.0 2.3 0.00081 19.0 1.6 2.1 2 0 0 2 2 2 1 Zinc knuckle RWD PF05773.17 EMC83655.1 - 3e-20 72.1 0.0 1.2e-19 70.2 0.0 2.1 1 0 0 1 1 1 1 RWD domain OB_NTP_bind PF07717.11 EMC83655.1 - 1.8e-19 69.6 0.0 5.2e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC83655.1 - 2.5e-19 69.1 1.1 1e-18 67.1 0.0 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC83655.1 - 4.9e-13 48.7 0.0 3.7e-12 45.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC83655.1 - 5.2e-10 39.0 0.3 1.7e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC83655.1 - 0.00014 22.0 0.1 0.00057 20.0 0.1 2.1 1 0 0 1 1 1 1 AAA domain zf-CCCH PF00642.19 EMC83655.1 - 0.00017 21.1 4.8 0.00017 21.1 3.3 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Arch_ATPase PF01637.13 EMC83655.1 - 0.0014 18.4 0.0 0.0082 15.8 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EMC83655.1 - 0.0032 17.3 1.0 0.055 13.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain UBA PF00627.26 EMC83655.1 - 0.0089 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain T2SE PF00437.15 EMC83655.1 - 0.022 13.6 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EMC83655.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EMC83655.1 - 0.16 11.3 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-CCCH_2 PF14608.1 EMC83655.1 - 0.34 10.9 4.1 0.96 9.5 2.8 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3347 PF11827.3 EMC83655.1 - 0.73 9.8 9.9 0.22 11.4 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) MORN PF02493.15 EMC83656.1 - 9.8e-06 25.0 1.4 1.1e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 MORN repeat RhoGEF PF00621.15 EMC83657.1 - 2e-16 60.3 3.9 2e-16 60.3 2.7 2.1 2 0 0 2 2 2 1 RhoGEF domain DUF4482 PF14818.1 EMC83657.1 - 0.16 12.6 6.5 0.099 13.2 2.7 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) Seryl_tRNA_N PF02403.17 EMC83657.1 - 0.25 11.3 5.9 0.59 10.1 4.1 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1192 PF06698.6 EMC83657.1 - 1.4 8.7 5.0 2.9 7.7 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) RasGEF PF00617.14 EMC83659.1 - 2.7e-51 173.9 0.6 6e-51 172.8 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC83659.1 - 6.4e-31 106.5 0.0 2.6e-30 104.5 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.15 EMC83659.1 - 1.3e-17 64.2 2.5 1.4e-17 64.1 0.1 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EMC83659.1 - 3.7e-13 49.5 0.2 2.3e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 PH domain Histone PF00125.19 EMC83659.1 - 2.9e-12 46.5 0.0 8.4e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH_10 PF15411.1 EMC83659.1 - 0.00024 21.2 0.0 0.00077 19.6 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Herpes_UL92 PF03048.9 EMC83659.1 - 0.0054 16.3 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 1 UL92 family CNH PF00780.17 EMC83660.1 - 6.3e-34 117.6 0.8 7.2e-34 117.4 0.6 1.0 1 0 0 1 1 1 1 CNH domain 7tm_1 PF00001.16 EMC83661.1 - 4.5e-09 35.8 0.1 5.9e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.1 EMC83664.1 - 1.3e-14 53.5 25.7 2.6e-08 33.7 0.9 4.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC83664.1 - 2.2e-13 49.6 16.4 3.7e-05 23.7 2.2 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83664.1 - 4.1e-06 26.7 27.7 0.00064 19.8 1.9 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC83664.1 - 0.0029 17.4 5.5 0.17 11.8 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC83664.1 - 0.011 15.4 10.2 1.2 8.8 0.6 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RRN7 PF11781.3 EMC83664.1 - 0.012 15.0 5.4 0.056 12.9 0.2 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-BED PF02892.10 EMC83664.1 - 0.38 10.5 10.7 0.38 10.5 4.0 2.8 1 1 2 3 3 3 0 BED zinc finger zf-met PF12874.2 EMC83664.1 - 0.79 10.0 9.0 0.57 10.4 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC83664.1 - 6.2 7.1 7.9 2.7 8.2 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding F-box-like PF12937.2 EMC83665.1 - 1.6e-08 34.0 0.6 1.6e-08 34.0 0.4 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EMC83665.1 - 6.5e-05 22.4 0.7 0.00042 19.8 0.1 2.3 2 0 0 2 2 2 1 F-box domain Borrelia_P83 PF05262.6 EMC83665.1 - 0.00021 19.7 5.6 0.00028 19.3 3.9 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Exonuc_VII_L PF02601.10 EMC83665.1 - 0.0043 16.2 7.7 0.0066 15.6 5.3 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit zf-C2H2 PF00096.21 EMC83665.1 - 0.0045 17.2 2.2 0.011 15.9 1.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83665.1 - 0.018 15.3 2.3 0.076 13.3 1.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC83665.1 - 0.081 12.8 0.4 0.25 11.2 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger UvrD_C PF13361.1 EMC83665.1 - 1.1 8.6 9.7 1.8 7.9 6.7 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PA PF02225.17 EMC83666.1 - 1.8e-14 53.2 0.0 3.2e-14 52.4 0.0 1.4 2 0 0 2 2 2 1 PA domain GH97_C PF14509.1 EMC83666.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation SET PF00856.23 EMC83667.1 - 1.8e-11 44.6 0.5 4.8e-10 39.9 0.4 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EMC83667.1 - 3.2e-06 26.9 12.4 3.2e-06 26.9 8.6 2.9 3 2 0 3 3 3 1 MYND finger zf-HIT PF04438.11 EMC83667.1 - 0.01 15.4 4.1 0.01 15.4 2.8 2.8 2 0 0 2 2 2 0 HIT zinc finger Homeobox PF00046.24 EMC83668.1 - 2.1e-22 78.5 4.5 2.8e-22 78.0 3.2 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 EMC83669.1 - 1.9e-22 78.6 3.1 2.9e-22 78.0 2.2 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC83669.1 - 0.048 12.7 0.3 0.086 11.9 0.2 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Polyketide_cyc PF03364.15 EMC83669.1 - 0.098 12.6 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport GlgS PF08971.6 EMC83669.1 - 0.34 10.8 2.8 0.52 10.2 2.0 1.6 1 1 0 1 1 1 0 Glycogen synthesis protein HA PF03457.9 EMC83669.1 - 0.47 10.5 4.6 0.46 10.6 2.6 1.5 1 1 0 1 1 1 0 Helicase associated domain RBD-FIP PF09457.5 EMC83670.1 - 1.8e-20 72.4 8.9 3.9e-20 71.3 6.2 1.6 1 0 0 1 1 1 1 FIP domain Mtc PF03820.12 EMC83671.1 - 9.8e-89 297.0 0.5 1.1e-88 296.8 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Homeobox PF00046.24 EMC83672.1 - 3.6e-05 23.2 1.4 6e-05 22.5 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain adh_short PF00106.20 EMC83674.1 - 2e-07 31.0 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase CHCH PF06747.8 EMC83674.1 - 0.0028 17.5 0.2 0.0052 16.6 0.1 1.5 1 0 0 1 1 1 1 CHCH domain adh_short_C2 PF13561.1 EMC83674.1 - 0.079 12.7 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.20 EMC83675.1 - 6.2e-13 48.4 0.0 6.9e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83675.1 - 0.00027 20.1 0.0 0.00033 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3248 PF11609.3 EMC83676.1 - 0.073 12.7 0.1 32 4.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3248) HupE_UreJ PF04955.7 EMC83676.1 - 0.44 9.8 17.0 1.2 8.3 5.6 2.9 1 1 2 3 3 3 0 HupE / UreJ protein WHIM2 PF15613.1 EMC83676.1 - 0.46 10.5 2.4 31 4.7 0.0 3.3 3 2 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 2 Astacin PF01400.19 EMC83677.1 - 5.4e-62 208.5 0.8 6.2e-62 208.3 0.1 1.4 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.15 EMC83677.1 - 9.5e-29 99.6 0.0 2.9e-28 98.1 0.0 1.8 2 0 0 2 2 2 1 CUB domain SH3_9 PF14604.1 EMC83679.1 - 7.9e-09 34.9 0.0 1.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC83679.1 - 0.00073 18.8 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain IncA PF04156.9 EMC83679.1 - 0.078 12.5 3.1 0.2 11.2 1.6 1.9 1 1 1 2 2 2 0 IncA protein C1q PF00386.16 EMC83680.1 - 5.3e-70 233.3 2.0 1.3e-37 128.6 0.1 2.1 2 0 0 2 2 2 2 C1q domain DUF3531 PF12049.3 EMC83680.1 - 0.018 14.6 0.2 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) FAM180 PF15173.1 EMC83681.1 - 1.2e-24 86.6 0.0 1.4e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 FAM180 family Complex1_30kDa PF00329.14 EMC83682.1 - 2.4e-33 114.4 0.1 3.2e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BTB PF00651.26 EMC83683.1 - 5.2e-26 90.8 2.2 9.5e-26 89.9 1.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 EMC83683.1 - 1.4e-17 62.9 3.1 6e-05 23.0 0.1 5.4 3 1 2 5 5 5 3 Kelch motif BACK PF07707.10 EMC83683.1 - 7.7e-10 38.5 0.7 8.4e-08 31.9 0.1 2.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 EMC83683.1 - 1.3e-08 34.2 1.5 0.058 12.9 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EMC83683.1 - 3e-07 29.9 0.4 0.04 13.6 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EMC83683.1 - 7.3e-07 29.1 0.2 0.022 14.9 0.1 4.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC83683.1 - 0.00023 21.0 1.5 0.061 13.2 0.0 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 EMC83683.1 - 0.0033 17.1 0.2 1 9.2 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain DSPc PF00782.15 EMC83684.1 - 3.5e-19 68.7 0.1 4.1e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC83684.1 - 8.6e-06 25.2 0.3 1.8e-05 24.2 0.2 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC83684.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPn PF14671.1 EMC83684.1 - 0.003 17.5 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase2 PF03162.8 EMC83684.1 - 0.012 15.0 0.1 0.012 14.9 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EMC83684.1 - 0.077 13.2 0.1 0.15 12.3 0.0 1.7 1 1 1 2 2 2 0 Tyrosine phosphatase family RRM_1 PF00076.17 EMC83685.1 - 1.6e-51 171.7 0.0 4.2e-18 64.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC83685.1 - 1.5e-37 127.3 0.1 1.5e-11 44.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC83685.1 - 1.4e-29 101.6 0.5 1.5e-09 37.5 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EMC83685.1 - 2.4e-06 27.4 0.0 0.4 10.7 0.0 3.5 3 0 0 3 3 3 3 RNA binding domain Nup35_RRM_2 PF14605.1 EMC83685.1 - 0.003 17.2 0.0 0.53 10.1 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EMC83685.1 - 0.062 13.0 0.2 5.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 Rapsyn_N PF10579.4 EMC83687.1 - 2.2e-44 149.1 0.2 3.4e-43 145.3 0.1 2.6 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.1 EMC83687.1 - 3.8e-23 81.2 7.5 6.3e-09 35.6 0.0 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMC83687.1 - 7.5e-21 72.8 11.6 0.00014 21.3 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EMC83687.1 - 9.8e-18 63.5 10.1 4.4e-06 26.2 0.5 5.4 2 2 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 EMC83687.1 - 7.9e-16 56.6 12.0 0.004 16.9 0.1 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC83687.1 - 2.9e-10 39.1 4.8 0.06 13.1 0.0 6.4 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC83687.1 - 1.7e-09 36.7 12.0 0.066 13.0 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC83687.1 - 4.5e-07 30.1 0.6 4.8 7.5 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC83687.1 - 1.2e-06 28.2 1.6 0.0046 16.8 0.1 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC83687.1 - 7.6e-06 26.4 0.3 17 6.2 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMC83687.1 - 2.1e-05 24.7 2.6 1.4 9.7 0.0 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.2 EMC83687.1 - 8.4e-05 22.4 1.0 0.57 10.0 0.0 3.8 2 1 1 3 3 3 2 Domain of Unknown Function (DUF3856) SNAP PF14938.1 EMC83687.1 - 0.00044 19.4 0.6 0.48 9.5 0.2 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP zf-RING_2 PF13639.1 EMC83687.1 - 0.0037 17.0 0.3 0.0037 17.0 0.2 3.4 4 0 0 4 4 4 1 Ring finger domain Fis1_TPR_C PF14853.1 EMC83687.1 - 0.0037 17.0 3.3 0.31 10.9 0.0 4.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EMC83687.1 - 0.0075 16.6 5.9 2.1 8.9 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.4 EMC83687.1 - 0.011 15.0 5.6 4.4 6.6 0.1 3.9 2 1 2 4 4 4 0 26S proteasome subunit RPN7 Apc5 PF12862.2 EMC83687.1 - 0.053 13.3 1.2 11 5.9 0.4 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 EMC83687.1 - 0.2 11.7 11.8 2.6 8.2 0.9 4.1 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMC83687.1 - 0.75 10.1 11.4 2.5 8.5 0.3 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat AAA PF00004.24 EMC83688.1 - 6.5e-42 142.8 0.0 1.3e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC83688.1 - 2.8e-06 27.0 0.1 1.2e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC83688.1 - 1.6e-05 24.9 0.1 0.00095 19.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EMC83688.1 - 2.3e-05 23.5 0.1 8.2e-05 21.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC83688.1 - 0.00011 22.2 0.4 0.016 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EMC83688.1 - 0.00016 21.6 0.0 0.00066 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMC83688.1 - 0.002 17.0 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 EMC83688.1 - 0.0021 17.3 0.0 0.0098 15.1 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 EMC83688.1 - 0.0022 17.8 0.1 0.0043 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMC83688.1 - 0.0044 16.2 0.1 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMC83688.1 - 0.0048 16.6 0.2 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMC83688.1 - 0.0049 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EMC83688.1 - 0.024 13.7 0.1 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EMC83688.1 - 0.025 14.1 0.2 0.062 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMC83688.1 - 0.027 15.3 0.1 0.073 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMC83688.1 - 0.03 13.7 1.0 0.26 10.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMC83688.1 - 0.033 13.6 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EMC83688.1 - 0.045 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMC83688.1 - 0.046 12.8 0.1 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 EMC83688.1 - 0.084 12.5 0.3 2.3 7.8 0.0 2.4 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.8 EMC83688.1 - 0.087 11.5 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus Urm1 PF09138.6 EMC83688.1 - 0.092 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) AAA_11 PF13086.1 EMC83688.1 - 0.1 12.1 0.1 0.62 9.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMC83688.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Claudin_2 PF13903.1 EMC83689.1 - 5.2e-17 62.0 4.4 6e-17 61.8 3.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC83689.1 - 0.0013 18.3 3.9 0.0022 17.6 2.7 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2776 PF10951.3 EMC83689.1 - 0.0035 16.4 0.3 0.0038 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2776) Zip PF02535.17 EMC83690.1 - 4.4e-57 193.4 1.0 6.2e-57 192.9 0.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Ets PF00178.17 EMC83691.1 - 8.8e-30 102.6 4.4 1.3e-29 102.1 3.1 1.2 1 0 0 1 1 1 1 Ets-domain Med23 PF11573.3 EMC83691.1 - 0.37 8.0 1.4 0.53 7.5 1.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 23 I-set PF07679.11 EMC83692.1 - 2.5e-105 344.5 14.0 5.6e-17 61.3 0.0 9.3 9 1 0 9 9 9 8 Immunoglobulin I-set domain fn3 PF00041.16 EMC83692.1 - 2.5e-41 139.6 0.0 1.9e-12 47.1 0.0 4.3 4 0 0 4 4 4 3 Fibronectin type III domain Ig_2 PF13895.1 EMC83692.1 - 1.7e-39 133.8 0.0 6.3e-08 32.6 0.0 8.3 7 1 1 8 8 8 8 Immunoglobulin domain ig PF00047.20 EMC83692.1 - 1e-31 108.8 1.2 4.1e-05 23.6 0.0 8.2 8 1 0 8 8 8 6 Immunoglobulin domain V-set PF07686.12 EMC83692.1 - 8.7e-31 106.1 4.4 0.00085 19.1 0.1 9.6 7 2 1 8 8 8 6 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC83692.1 - 1.1e-17 64.2 0.0 0.00056 20.3 0.0 9.1 9 2 0 9 9 9 3 Immunoglobulin domain C2-set_2 PF08205.7 EMC83692.1 - 3e-10 39.8 0.1 0.035 14.0 0.0 6.4 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC83692.1 - 1.4e-05 25.0 5.9 13 5.8 0.0 7.3 6 1 1 7 7 7 1 Immunoglobulin C1-set domain Herpes_gI PF01688.12 EMC83692.1 - 0.0012 18.0 0.2 7.1 5.7 0.0 4.4 5 0 0 5 5 5 2 Alphaherpesvirus glycoprotein I Herpes_gE PF02480.11 EMC83692.1 - 0.02 13.1 0.7 0.11 10.6 0.0 2.5 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E Hormone_recep PF00104.25 EMC83693.1 - 3.3e-34 117.8 1.8 5.3e-34 117.1 1.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC83693.1 - 7.4e-28 96.5 15.5 1.2e-27 95.8 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) His_Phos_2 PF00328.17 EMC83696.1 - 2.9e-37 128.8 0.0 3.4e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.27 EMC83697.1 - 4.3e-11 42.2 12.7 9.5e-05 22.1 0.1 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.3 EMC83697.1 - 0.025 12.7 0.0 0.036 12.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FCH PF00611.18 EMC83698.1 - 6e-24 84.0 3.2 6.9e-23 80.6 0.1 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMC83698.1 - 2.9e-16 58.7 0.1 6.7e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC83698.1 - 1.1e-15 56.7 0.8 3.5e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMC83698.1 - 7.4e-09 34.9 0.0 3.6e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain DUF3450 PF11932.3 EMC83698.1 - 0.0028 16.9 5.4 0.0052 16.0 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Tho2 PF11262.3 EMC83698.1 - 0.038 13.0 8.1 0.084 11.9 5.3 1.8 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 bZIP_Maf PF03131.12 EMC83698.1 - 0.061 13.6 8.5 0.17 12.1 5.9 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF3086 PF11285.3 EMC83698.1 - 0.14 10.9 3.9 0.12 11.1 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3086) CorA PF01544.13 EMC83698.1 - 0.64 8.9 2.6 0.57 9.1 0.8 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Bap31 PF05529.7 EMC83698.1 - 1.3 8.4 9.6 2.3 7.6 6.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3391 PF11871.3 EMC83698.1 - 1.4 9.1 6.8 1.3 9.1 3.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PilJ PF13675.1 EMC83698.1 - 1.5 9.2 5.0 6.1 7.2 0.4 2.7 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term V_ATPase_I PF01496.14 EMC83698.1 - 3.1 5.5 6.2 4.2 5.1 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ArfGap PF01412.13 EMC83699.1 - 8.8e-29 99.6 1.7 2.1e-28 98.4 1.2 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ldl_recept_b PF00058.12 EMC83701.1 - 6.4e-193 624.9 66.2 1.1e-13 51.2 0.1 20.6 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.13 EMC83701.1 - 6.7e-88 288.3 170.9 1.4e-12 47.3 11.2 9.2 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.1 EMC83701.1 - 2.6e-46 155.4 117.1 3.6e-12 46.1 5.8 8.6 8 0 0 8 8 8 6 Coagulation Factor Xa inhibitory site SGL PF08450.7 EMC83701.1 - 9.3e-31 107.0 28.7 3.8e-08 33.0 2.5 11.3 3 3 6 10 10 10 7 SMP-30/Gluconolaconase/LRE-like region cEGF PF12662.2 EMC83701.1 - 3.4e-12 45.7 40.2 1e-07 31.4 0.8 7.6 6 0 0 6 6 6 5 Complement Clr-like EGF-like NHL PF01436.16 EMC83701.1 - 0.00038 20.2 6.1 85 3.3 0.0 8.5 9 0 0 9 9 9 0 NHL repeat Str_synth PF03088.11 EMC83701.1 - 0.0016 18.4 0.0 13 5.8 0.0 5.9 6 0 0 6 6 6 1 Strictosidine synthase EGF PF00008.22 EMC83701.1 - 0.0054 16.6 2.4 0.0054 16.6 1.7 14.0 15 0 0 15 15 15 5 EGF-like domain SBBP PF06739.6 EMC83701.1 - 0.039 13.7 2.0 8.6 6.2 0.0 4.6 5 0 0 5 5 5 0 Beta-propeller repeat Trypsin PF00089.21 EMC83702.1 - 7.9e-68 228.3 0.0 1.1e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 EMC83702.1 - 1.6e-43 146.6 13.1 6.6e-23 80.5 3.2 2.6 2 0 0 2 2 2 2 Kringle domain Thrombin_light PF09396.5 EMC83702.1 - 4e-27 93.5 2.0 8.8e-27 92.4 1.4 1.6 1 0 0 1 1 1 1 Thrombin light chain Gla PF00594.15 EMC83702.1 - 2.4e-17 62.3 5.1 5.3e-17 61.2 3.6 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.6 EMC83702.1 - 3.5e-06 26.5 0.1 6.2e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) zf-H2C2_2 PF13465.1 EMC83703.1 - 3e-57 188.2 67.0 1.4e-09 37.7 0.3 11.2 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.21 EMC83703.1 - 1.4e-39 132.0 76.6 4.7e-07 29.7 0.4 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83703.1 - 2.7e-28 96.1 73.8 0.00023 21.2 0.6 10.3 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC83703.1 - 2.5e-14 52.6 51.8 0.004 17.0 0.1 10.1 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83703.1 - 5e-13 48.7 37.6 0.0016 18.5 0.0 9.3 10 0 0 10 10 8 6 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 EMC83703.1 - 0.0004 20.9 15.0 1.8 9.2 0.4 6.0 3 3 2 5 5 5 2 Protein of unknown function (FYDLN_acid) GAGA PF09237.6 EMC83703.1 - 0.00052 19.5 0.3 0.00052 19.5 0.2 4.5 1 1 4 5 5 5 1 GAGA factor zf-Di19 PF05605.7 EMC83703.1 - 0.00074 19.5 1.7 0.00074 19.5 1.1 6.7 4 3 2 6 6 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EMC83703.1 - 0.0058 16.8 3.0 0.11 12.7 0.4 9.0 10 0 0 10 10 8 2 Zinc-finger of C2H2 type zinc_ribbon_2 PF13240.1 EMC83703.1 - 0.0063 15.9 37.6 0.045 13.2 1.0 7.3 7 1 0 7 7 7 2 zinc-ribbon domain C1_4 PF07975.7 EMC83703.1 - 0.025 14.5 3.9 0.025 14.5 2.7 6.8 3 3 4 7 7 6 0 TFIIH C1-like domain DZR PF12773.2 EMC83703.1 - 0.035 13.9 40.4 2.2 8.1 2.8 5.7 3 2 0 3 3 3 0 Double zinc ribbon Elf1 PF05129.8 EMC83703.1 - 0.091 12.4 0.1 0.091 12.4 0.1 5.8 1 1 6 7 7 7 0 Transcription elongation factor Elf1 like zf-FCS PF06467.9 EMC83703.1 - 0.13 11.9 37.5 8.2 6.1 0.9 9.0 5 3 5 10 10 10 0 MYM-type Zinc finger with FCS sequence motif BHD_1 PF10403.4 EMC83703.1 - 0.14 11.6 0.9 1.3 8.6 0.0 2.9 4 0 0 4 4 3 0 Rad4 beta-hairpin domain 1 zf-C2HC_2 PF13913.1 EMC83703.1 - 0.15 11.7 0.1 0.15 11.7 0.1 7.8 10 0 0 10 10 7 0 zinc-finger of a C2HC-type DUF2180 PF09947.4 EMC83703.1 - 0.18 11.5 0.1 0.18 11.5 0.1 6.4 5 3 2 8 8 8 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.2 EMC83703.1 - 0.66 10.1 0.0 0.66 10.1 0.0 8.8 1 1 7 9 9 9 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 EMC83703.1 - 4.7 7.2 51.5 2 8.4 0.1 9.1 5 2 3 8 8 8 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 EMC83703.1 - 6 6.7 24.6 1.1 9.1 0.0 6.5 6 1 1 7 7 7 0 PhnA Zinc-Ribbon RhoGAP PF00620.22 EMC83704.1 - 8.3e-45 152.1 0.2 1.7e-44 151.0 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EMC83704.1 - 1.6e-40 138.4 5.1 3.1e-40 137.4 1.2 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EMC83704.1 - 8.3e-10 38.3 0.2 1.6e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain ATG13 PF10033.4 EMC83705.1 - 9.9e-33 113.5 0.0 2.4e-32 112.2 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 13 DDE_Tnp_4 PF13359.1 EMC83706.1 - 3.4e-36 124.2 0.0 4.7e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 EMC83706.1 - 9.7e-07 28.3 0.0 5.1e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 EMC83706.1 - 0.0038 16.7 0.0 2 7.9 0.1 2.1 1 1 1 2 2 2 2 Transposase DDE domain HTH_Tnp_4 PF13613.1 EMC83706.1 - 0.064 12.7 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease 7tm_1 PF00001.16 EMC83707.1 - 6.1e-82 274.6 6.8 1e-81 273.9 4.7 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83707.1 - 6.6e-07 28.7 15.6 7.7e-06 25.2 4.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx PgaD PF13994.1 EMC83707.1 - 0.075 12.5 3.8 0.092 12.2 0.2 2.5 2 0 0 2 2 2 0 PgaD-like protein PTN_MK_N PF05196.8 EMC83708.1 - 2.5e-28 97.8 18.9 2.5e-28 97.8 13.1 2.3 2 1 0 2 2 2 1 PTN/MK heparin-binding protein family, N-terminal domain PTN_MK_C PF01091.13 EMC83708.1 - 8e-27 93.0 3.8 8e-27 93.0 2.6 2.7 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain DAGK_acc PF00609.14 EMC83709.1 - 6.2e-39 133.7 0.0 1.2e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EMC83709.1 - 1.3e-33 115.2 0.0 3.6e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.2 EMC83709.1 - 4.3e-15 55.8 0.2 5.2e-08 33.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) C1_1 PF00130.17 EMC83709.1 - 3.5e-12 45.8 26.0 9.6e-10 38.0 9.7 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_5 PF13857.1 EMC83709.1 - 5.6e-11 42.3 0.0 2.5e-05 24.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC83709.1 - 1.8e-10 40.0 0.0 2.4e-05 24.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC83709.1 - 3.2e-09 37.0 0.1 0.00019 21.8 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC83709.1 - 7.9e-09 34.8 0.0 0.00085 19.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat bZIP_1 PF00170.16 EMC83710.1 - 2.2e-15 56.3 13.9 4.6e-15 55.3 9.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC83710.1 - 1.3e-09 37.7 9.2 1.3e-09 37.7 6.4 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC83710.1 - 2e-05 24.8 10.1 3.8e-05 23.8 7.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor TPR_MLP1_2 PF07926.7 EMC83710.1 - 0.058 13.1 10.1 0.089 12.5 7.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Transposase_22 PF02994.9 EMC83710.1 - 0.076 11.4 5.0 0.11 10.9 3.4 1.1 1 0 0 1 1 1 0 L1 transposable element APG6 PF04111.7 EMC83710.1 - 0.13 11.2 6.7 0.2 10.6 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3552 PF12072.3 EMC83710.1 - 0.2 10.8 9.3 0.3 10.2 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ADIP PF11559.3 EMC83710.1 - 0.21 11.4 11.7 0.35 10.7 8.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 EMC83710.1 - 3.1 7.6 5.2 2.2 8.1 1.8 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PHD PF00628.24 EMC83711.1 - 9.6e-13 47.6 6.5 2.1e-12 46.5 4.5 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EMC83711.1 - 0.0011 18.6 3.3 0.016 14.9 1.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EMC83711.1 - 0.0012 18.1 0.8 0.0031 16.7 0.6 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EMC83711.1 - 0.0013 18.4 1.1 0.0013 18.4 0.8 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.14 EMC83711.1 - 0.0065 16.0 2.0 0.019 14.5 1.4 1.8 1 0 0 1 1 1 1 AT hook motif zf-HC5HC2H PF13771.1 EMC83711.1 - 0.021 14.9 2.5 0.021 14.9 0.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain ADK_lid PF05191.9 EMC83711.1 - 0.035 13.7 2.0 0.13 11.9 1.4 2.0 1 0 0 1 1 1 0 Adenylate kinase, active site lid PhnA_Zn_Ribbon PF08274.7 EMC83711.1 - 0.19 11.5 1.3 4.9 7.0 0.1 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_2 PF13639.1 EMC83711.1 - 0.74 9.6 7.5 1.5 8.7 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain C1_3 PF07649.7 EMC83711.1 - 1.4 8.9 4.8 2.6 8.1 3.4 1.5 1 0 0 1 1 1 0 C1-like domain Seryl_tRNA_N PF02403.17 EMC83711.1 - 1.7 8.6 13.9 0.59 10.1 3.2 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Erp_C PF06780.6 EMC83711.1 - 4.1 7.2 10.1 0.2 11.5 2.7 1.9 2 0 0 2 2 2 0 Erp protein C-terminus Pex16 PF08610.5 EMC83714.1 - 2.5e-81 273.3 3.8 2.8e-81 273.1 2.7 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF29 PF01724.11 EMC83714.1 - 0.71 9.7 4.8 0.52 10.1 0.3 2.6 1 1 2 3 3 3 0 Domain of unknown function DUF29 Sulfotransfer_1 PF00685.22 EMC83716.1 - 4.7e-58 196.5 0.0 5.8e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC83716.1 - 2.5e-05 25.2 0.2 6.5e-05 23.9 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 EMC83716.1 - 0.057 12.9 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Stf0 sulphotransferase CUB PF00431.15 EMC83717.1 - 1e-62 209.0 0.1 2.3e-31 108.0 0.0 2.7 3 0 0 3 3 3 2 CUB domain Astacin PF01400.19 EMC83717.1 - 5e-59 198.9 0.0 7.4e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB_2 PF02408.15 EMC83717.1 - 0.11 12.0 2.1 0.96 9.0 0.0 2.6 2 0 0 2 2 2 0 CUB-like domain FYVE PF01363.16 EMC83718.1 - 0.00082 19.2 16.4 0.00082 19.2 11.4 2.7 2 0 0 2 2 2 1 FYVE zinc finger Cytochrome_CBB3 PF13442.1 EMC83718.1 - 0.2 11.8 0.2 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III PP1_inhibitor PF05361.7 EMC83719.1 - 9.9e-26 90.1 5.1 8.3e-25 87.1 3.6 1.9 1 1 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Pep3_Vps18 PF05131.9 EMC83720.1 - 2.3e-45 153.6 0.2 3.6e-44 149.7 0.0 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EMC83720.1 - 1.4e-11 44.1 18.1 1e-09 38.1 2.7 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 EMC83720.1 - 0.00061 19.9 0.4 0.0027 17.8 0.2 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EMC83720.1 - 0.00073 19.3 0.3 0.00073 19.3 0.2 2.7 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EMC83720.1 - 0.0061 16.2 0.3 0.024 14.3 0.2 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC83720.1 - 0.015 15.3 0.1 0.06 13.4 0.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1664 PF07889.7 EMC83720.1 - 0.03 14.1 1.3 0.061 13.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-Apc11 PF12861.2 EMC83720.1 - 0.03 14.1 0.2 0.11 12.4 0.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fib_alpha PF08702.5 EMC83720.1 - 0.037 14.1 1.4 0.74 9.9 0.1 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-C3HC4_2 PF13923.1 EMC83720.1 - 0.12 12.4 5.1 0.044 13.8 0.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ChaC PF04752.7 EMC83721.1 - 1.3e-31 109.9 0.0 1.5e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein SNF2_N PF00176.18 EMC83723.1 - 2.6e-71 239.8 5.7 2.6e-71 239.8 4.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EMC83723.1 - 7.1e-51 171.9 20.7 7.1e-51 171.9 14.3 3.8 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 EMC83723.1 - 6.2e-14 51.6 0.0 1.6e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF-hand_1 PF00036.27 EMC83724.1 - 5.2e-13 47.2 3.1 3.7e-06 25.8 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EMC83724.1 - 9.5e-12 43.7 1.7 3.2e-07 29.6 0.2 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EMC83724.1 - 7.6e-11 41.9 1.6 1.5e-10 41.0 0.5 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC83724.1 - 5.5e-07 29.1 3.5 1.6e-05 24.4 0.3 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC83724.1 - 1.4e-05 24.1 5.8 0.0084 15.4 0.2 3.2 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 EMC83724.1 - 0.00021 21.2 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.3 EMC83724.1 - 0.00064 19.4 0.2 0.002 17.8 0.0 1.9 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.2 EMC83724.1 - 0.047 13.4 1.5 1.3 8.8 0.1 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Yippee-Mis18 PF03226.9 EMC83725.1 - 2.3e-16 59.5 5.3 4.9e-16 58.5 3.7 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EMC83725.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EMC83725.1 - 0.49 10.0 3.8 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TRAUB PF08164.7 EMC83726.1 - 0.46 10.6 0.0 0.46 10.6 0.0 3.8 2 2 3 5 5 5 0 Apoptosis-antagonizing transcription factor, C-terminal Plus-3 PF03126.13 EMC83727.1 - 2e-37 127.4 0.0 2e-37 127.4 0.0 2.3 3 0 0 3 3 3 1 Plus-3 domain Sulfotransfer_2 PF03567.9 EMC83728.1 - 3.2e-44 151.5 4.6 3.8e-44 151.2 3.2 1.0 1 0 0 1 1 1 1 Sulfotransferase family Pkip-1 PF06878.6 EMC83728.1 - 0.00092 19.1 1.0 0.0052 16.6 0.2 2.1 2 0 0 2 2 2 1 Pkip-1 protein Pkinase_Tyr PF07714.12 EMC83729.1 - 4e-86 288.2 0.0 5.4e-86 287.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC83729.1 - 2.4e-34 118.6 0.0 3.6e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MAM PF00629.18 EMC83729.1 - 6.8e-23 81.1 0.1 2.2e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 MAM domain Gly_rich PF12810.2 EMC83729.1 - 2.7e-20 73.0 24.3 4.5e-20 72.2 16.8 1.2 1 0 0 1 1 1 1 Glycine rich protein Kinase-like PF14531.1 EMC83729.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RPAP1_C PF08620.5 EMC83730.1 - 2.3e-26 91.4 0.3 5.1e-26 90.3 0.2 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EMC83730.1 - 5.7e-17 61.0 2.4 1.6e-16 59.6 1.7 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal TMEM151 PF14857.1 EMC83731.1 - 1.7e-224 745.1 17.1 1.9e-224 744.9 11.8 1.0 1 0 0 1 1 1 1 TMEM151 family Pkinase_Tyr PF07714.12 EMC83732.1 - 2.1e-85 285.9 0.0 2.8e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC83732.1 - 3.7e-39 134.4 0.0 5.2e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 EMC83732.1 - 5.6e-18 64.5 1.7 2.4e-15 56.1 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain fn3 PF00041.16 EMC83732.1 - 3.2e-16 59.2 0.6 1.8e-10 40.7 0.4 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.1 EMC83732.1 - 3.4e-16 59.1 0.0 1.2e-11 44.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC83732.1 - 1.3e-09 38.3 5.2 0.0013 19.1 0.0 4.1 4 1 0 4 4 4 2 Immunoglobulin domain ig PF00047.20 EMC83732.1 - 7.5e-07 29.1 0.7 5.2e-06 26.4 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 EMC83732.1 - 2e-06 27.6 0.0 1.2e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain DUF4229 PF14012.1 EMC83732.1 - 0.034 14.0 0.2 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Kinase-like PF14531.1 EMC83732.1 - 0.042 12.8 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 EMC83733.1 - 2.5e-55 182.4 27.3 2.3e-08 33.5 0.3 12.7 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 EMC83733.1 - 5.5e-06 26.2 0.1 0.0002 21.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.1 EMC83733.1 - 0.015 14.2 0.0 5.4 5.9 0.0 2.7 3 0 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 Hira PF07569.6 EMC83733.1 - 0.034 13.3 0.2 0.33 10.1 0.0 2.7 2 0 0 2 2 2 0 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 EMC83733.1 - 0.12 10.6 2.0 1.4 7.0 0.1 3.1 3 2 0 3 3 3 0 Cytochrome D1 heme domain Bunya_NS-S PF01104.12 EMC83734.1 - 0.0094 15.4 0.3 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Bunyavirus non-structural protein NS-s PLA2_B PF01735.13 EMC83735.1 - 2.8e-27 95.0 0.0 3.9e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 EMC83736.1 - 2.4e-34 118.3 0.1 8.3e-31 106.6 0.0 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain C2 PF00168.25 EMC83736.1 - 6.9e-18 64.2 0.4 1.7e-17 63.0 0.3 1.7 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.13 EMC83737.1 - 1.1e-33 116.1 0.0 8.1e-32 110.0 0.0 2.7 2 1 1 3 3 3 2 Lysophospholipase catalytic domain C2 PF00168.25 EMC83737.1 - 9.4e-19 67.0 0.1 3.1e-18 65.4 0.1 1.9 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.13 EMC83738.1 - 1.6e-29 102.4 0.0 4.4e-28 97.6 0.0 2.3 2 1 0 2 2 2 2 Lysophospholipase catalytic domain C2 PF00168.25 EMC83738.1 - 2.1e-13 49.9 0.4 5.2e-13 48.6 0.3 1.7 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.13 EMC83739.1 - 5.5e-26 90.7 0.1 2.5e-25 88.5 0.0 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.25 EMC83739.1 - 1.8e-15 56.5 0.8 5.3e-15 55.0 0.6 1.9 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 EMC83739.1 - 0.074 12.5 0.3 1.9 7.9 0.1 2.4 2 0 0 2 2 2 0 CEP76 C2 domain C2 PF00168.25 EMC83740.1 - 1.3e-20 73.0 2.0 4.5e-19 68.0 0.2 2.1 1 1 1 2 2 2 2 C2 domain PhnH PF05845.7 EMC83740.1 - 0.006 16.0 0.0 0.0066 15.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnH) PLA2_B PF01735.13 EMC83741.1 - 5.6e-30 103.9 0.1 5.7e-29 100.6 0.0 2.2 2 1 1 3 3 3 1 Lysophospholipase catalytic domain C2 PF00168.25 EMC83741.1 - 9.8e-21 73.4 0.2 2.5e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 C2 domain Ish1 PF10281.4 EMC83741.1 - 0.086 12.9 0.0 0.76 9.9 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PLA2_B PF01735.13 EMC83742.1 - 2.3e-40 138.2 0.1 1.1e-33 116.1 0.0 3.0 2 1 0 2 2 2 2 Lysophospholipase catalytic domain C2 PF00168.25 EMC83742.1 - 3.2e-16 58.9 1.4 4.3e-16 58.5 0.1 1.9 2 0 0 2 2 2 1 C2 domain CNH PF00780.17 EMC83743.1 - 1e-48 166.1 0.1 2.3e-48 165.0 0.1 1.6 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 EMC83743.1 - 1.7e-32 111.6 2.8 1.7e-32 111.6 1.9 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EMC83743.1 - 1.4e-31 108.9 4.8 1.4e-31 108.9 3.4 2.7 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EMC83743.1 - 5.1e-12 45.6 11.8 1.1e-06 28.2 0.7 4.3 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-FCS PF06467.9 EMC83743.1 - 0.0074 15.9 0.2 0.019 14.5 0.1 1.8 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif Lgl_C PF08596.5 EMC83743.1 - 0.072 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal TPR_12 PF13424.1 EMC83743.1 - 0.075 12.9 0.5 87 3.1 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC83743.1 - 0.24 11.5 3.1 1.2 9.2 0.2 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Lung_7-TM_R PF06814.8 EMC83744.1 - 5.7e-79 265.1 21.8 6.8e-79 264.8 15.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Glyco_hydro_31 PF01055.21 EMC83745.1 - 8e-158 525.8 1.1 1.1e-157 525.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMC83745.1 - 2.2e-17 62.6 0.0 6.6e-17 61.1 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like chaperone_DMP PF10448.4 EMC83745.1 - 0.059 13.2 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 20S proteasome chaperone Peptidase_C2 PF00648.16 EMC83746.1 - 9.5e-150 497.5 0.4 5.4e-148 491.8 0.3 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMC83746.1 - 8.3e-60 200.6 0.0 2e-59 199.4 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 EMC83746.1 - 1.1e-18 65.0 10.8 5.2e-07 28.5 0.1 6.1 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EMC83746.1 - 3.1e-18 63.9 5.7 0.0006 19.4 0.0 5.9 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.1 EMC83746.1 - 2e-13 50.2 10.2 1.9e-05 24.7 0.2 4.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC83746.1 - 8.6e-13 47.6 12.3 1.6e-09 37.2 0.5 4.5 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC83746.1 - 7.4e-12 44.0 7.7 0.00026 20.1 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 EMC83746.1 - 0.018 14.8 3.3 1 9.1 0.2 2.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.27 EMC83747.1 - 2.1e-32 109.8 6.4 1.2e-05 25.0 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-C2H2_jaz PF12171.3 EMC83747.1 - 0.00063 19.8 5.9 0.058 13.5 0.8 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC83747.1 - 0.00077 19.5 7.5 0.091 13.0 1.0 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type PQQ_3 PF13570.1 EMC83747.1 - 0.071 13.3 1.5 2.1e+02 2.3 0.0 5.1 6 0 0 6 6 6 0 PQQ-like domain AKAP95 PF04988.7 EMC83747.1 - 0.31 10.7 14.6 0.58 9.9 0.7 2.9 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) PQQ PF01011.16 EMC83747.1 - 0.37 10.4 1.3 2.2e+02 1.6 0.0 4.7 5 0 0 5 5 5 0 PQQ enzyme repeat zf-C2H2_2 PF12756.2 EMC83747.1 - 3 8.0 20.9 0.93 9.6 2.9 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) SNARE PF05739.14 EMC83748.1 - 7.3e-21 73.6 16.9 1.6e-15 56.5 5.2 2.4 2 0 0 2 2 2 2 SNARE domain SNAP-25 PF00835.14 EMC83748.1 - 3.1e-13 50.2 0.7 5.4e-13 49.4 0.5 1.4 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.3 EMC83748.1 - 0.00016 21.6 4.6 0.014 15.4 0.8 2.6 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus MscS_porin PF12795.2 EMC83748.1 - 0.14 11.4 5.4 0.32 10.2 0.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Sec20 PF03908.8 EMC83748.1 - 0.15 11.8 2.7 0.12 12.1 0.5 1.8 2 0 0 2 2 2 0 Sec20 LTXXQ PF07813.7 EMC83748.1 - 0.15 12.5 1.4 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein DUF4200 PF13863.1 EMC83748.1 - 0.25 11.2 6.0 2.3 8.1 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF16 PF01519.11 EMC83748.1 - 0.48 10.6 5.2 1.4 9.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.7 EMC83748.1 - 2.5 7.8 7.8 0.61 9.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG6 PF06419.6 EMC83748.1 - 2.6 6.0 7.4 1.4 6.9 1.0 2.0 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 LRR_4 PF12799.2 EMC83749.1 - 4.2e-29 99.6 29.4 1.5e-09 37.2 2.8 5.1 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC83749.1 - 5.2e-21 74.1 19.9 3.1e-13 49.2 0.5 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EMC83749.1 - 9.2e-18 61.5 23.1 0.057 13.4 0.0 8.0 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC83749.1 - 1e-11 43.0 23.9 0.17 12.2 0.3 7.9 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EMC83749.1 - 1.2e-09 37.1 24.3 0.68 10.1 1.2 7.6 6 1 1 7 7 7 6 Leucine Rich repeat LRR_9 PF14580.1 EMC83749.1 - 3.9e-05 23.2 7.1 0.001 18.6 0.9 2.1 1 1 1 2 2 2 2 Leucine-rich repeat HAUS2 PF15003.1 EMC83750.1 - 4.3e-34 117.8 5.1 4.9e-34 117.6 3.5 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Vac_Fusion PF02346.11 EMC83750.1 - 0.26 10.7 1.7 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Chordopoxvirus fusion protein SAS4 PF15460.1 EMC83750.1 - 0.38 10.6 2.3 0.3 10.9 0.3 1.8 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DASH_Dad1 PF08649.5 EMC83750.1 - 1.3 8.7 3.9 6.1 6.6 0.0 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 Kinesin PF00225.18 EMC83751.1 - 6.8e-105 350.4 0.1 6.8e-105 350.4 0.1 2.3 3 0 0 3 3 3 1 Kinesin motor domain FHA PF00498.21 EMC83751.1 - 3e-07 30.4 1.3 1e-06 28.7 0.1 2.5 2 0 0 2 2 2 1 FHA domain START PF01852.14 EMC83752.1 - 2.5e-08 33.4 0.0 5.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 START domain Tetraspannin PF00335.15 EMC83753.1 - 6.1e-49 166.2 18.7 1.5e-48 164.9 13.0 1.6 1 1 0 1 1 1 1 Tetraspanin family ArfGap PF01412.13 EMC83753.1 - 0.15 11.8 2.8 0.34 10.7 1.9 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Metallophos_2 PF12850.2 EMC83754.1 - 0.0012 18.7 0.0 0.0037 17.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Big_3_4 PF13754.1 EMC83754.1 - 0.22 11.8 0.0 0.49 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) ADH_zinc_N PF00107.21 EMC83755.1 - 1.4e-17 63.4 0.0 2.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC83755.1 - 1.9e-12 48.1 0.0 4.8e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Orthopox_F14 PF06076.7 EMC83755.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus F14 protein ELM2 PF01448.19 EMC83756.1 - 8.8e-13 48.6 1.4 2e-12 47.5 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 EMC83756.1 - 0.0044 17.0 0.0 0.0093 16.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain LRR_4 PF12799.2 EMC83758.1 - 8.2e-17 60.4 12.5 3.8e-07 29.5 5.2 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC83758.1 - 6.2e-09 35.4 8.7 0.00053 19.6 0.0 3.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 EMC83758.1 - 4.3e-07 29.6 0.9 1.1e-06 28.2 0.4 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EMC83758.1 - 4.4e-06 25.9 10.3 1.6 9.0 0.4 5.1 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 EMC83758.1 - 0.00042 20.0 5.8 1.5 9.1 0.8 4.6 2 1 2 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 EMC83758.1 - 0.0044 16.9 9.0 8.2 7.1 0.7 5.6 4 2 2 6 6 6 1 Leucine rich repeat P-mevalo_kinase PF04275.9 EMC83758.1 - 0.1 12.3 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Phosphomevalonate kinase Death PF00531.17 EMC83758.1 - 0.15 11.8 1.0 19 5.0 0.0 3.0 3 0 0 3 3 3 0 Death domain BAAT_C PF08840.6 EMC83759.1 - 5e-81 271.4 0.0 6e-81 271.2 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.9 EMC83759.1 - 3.7e-17 62.2 0.0 5.4e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.13 EMC83759.1 - 1.3e-07 31.1 0.0 0.021 14.0 0.0 3.3 2 2 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC83759.1 - 6.8e-06 25.8 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC83759.1 - 2.3e-05 23.6 0.0 0.00046 19.4 0.0 2.6 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EMC83759.1 - 4.1e-05 23.1 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cupin_4 PF08007.7 EMC83760.1 - 1.8e-58 198.3 0.0 2.4e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 EMC83760.1 - 3.7e-06 26.6 0.0 4.2e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EMC83760.1 - 0.007 15.8 0.0 0.61 9.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain NumbF PF06311.7 EMC83761.1 - 4.1e-39 132.5 0.9 4.1e-39 132.5 0.6 3.0 3 0 0 3 3 3 1 NUMB domain PID PF00640.18 EMC83761.1 - 8.7e-36 122.9 0.1 1.4e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 EMC83761.1 - 2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 EMC83761.1 - 4.6e-05 23.1 0.1 9.1e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) I-set PF07679.11 EMC83762.1 - 1.6e-44 149.6 0.0 4.5e-15 55.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83762.1 - 2.9e-35 120.2 0.1 3.2e-11 43.1 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain ADAM_spacer1 PF05986.9 EMC83762.1 - 1.2e-34 118.5 0.0 2.1e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Ig_3 PF13927.1 EMC83762.1 - 5.2e-30 103.7 7.8 8.7e-10 38.9 0.2 4.4 4 0 0 4 4 4 3 Immunoglobulin domain TSP_1 PF00090.14 EMC83762.1 - 3.7e-29 100.5 73.5 5.1e-08 32.9 8.8 6.4 5 0 0 5 5 5 5 Thrombospondin type 1 domain V-set PF07686.12 EMC83762.1 - 2.3e-27 95.1 0.3 6.1e-09 35.7 0.0 4.7 3 2 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.20 EMC83762.1 - 9.6e-27 92.8 2.5 7.2e-09 35.6 0.1 4.1 4 0 0 4 4 4 3 Immunoglobulin domain Kunitz_BPTI PF00014.18 EMC83762.1 - 8.9e-18 64.2 5.4 8.9e-18 64.2 3.8 4.8 5 1 0 5 5 4 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PLAC PF08686.6 EMC83762.1 - 2.6e-11 43.5 7.3 2.6e-11 43.5 5.0 2.5 2 0 0 2 2 1 1 PLAC (protease and lacunin) domain V-set_CD47 PF08204.6 EMC83762.1 - 0.00039 20.1 0.0 0.12 12.1 0.0 3.0 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain C2-set PF05790.10 EMC83762.1 - 0.002 18.0 0.0 4.7 7.2 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Presenilin PF01080.12 EMC83763.1 - 2.6e-178 592.9 8.7 2.6e-178 592.9 6.0 1.3 1 1 0 1 1 1 1 Presenilin PBP1_TM PF14812.1 EMC83763.1 - 0.34 11.2 5.9 0.44 10.8 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CHD5 PF04420.9 EMC83763.1 - 0.37 10.4 2.6 1.4 8.5 1.8 1.9 1 0 0 1 1 1 0 CHD5-like protein DUF912 PF06024.7 EMC83763.1 - 2.5 8.1 18.3 0.49 10.4 0.1 4.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FYVE PF01363.16 EMC83764.1 - 1.8e-23 82.1 20.8 3.7e-16 58.7 4.4 5.6 5 1 1 6 6 6 2 FYVE zinc finger GBP PF02263.14 EMC83764.1 - 0.00031 19.8 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AIG1 PF04548.11 EMC83764.1 - 0.0017 17.5 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family WD40 PF00400.27 EMC83765.1 - 0.0068 16.2 0.4 0.59 10.1 0.0 3.5 3 1 0 3 3 3 1 WD domain, G-beta repeat RGS PF00615.14 EMC83767.1 - 1.1e-21 77.1 2.7 1.3e-21 76.8 0.0 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EMC83767.1 - 1.2e-15 56.9 0.0 2.8e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 EMC83767.1 - 8e-15 54.3 0.1 1.9e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 GGL domain DUF1203 PF06718.6 EMC83767.1 - 0.016 14.9 0.0 0.094 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) Ribosomal_L25p PF01386.14 EMC83767.1 - 0.037 14.1 0.1 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal L25p family CDI PF02234.14 EMC83767.1 - 1.4 8.7 4.7 2.3 8.0 0.9 3.0 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor Pecanex_C PF05041.10 EMC83768.1 - 1e-119 397.7 0.0 1.6e-119 397.1 0.0 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) TPR_1 PF00515.23 EMC83769.1 - 8.8e-08 31.4 3.1 9e-07 28.2 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC83769.1 - 1.9e-07 30.4 2.2 1.2e-06 27.9 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMC83769.1 - 6.1e-05 22.5 3.3 0.00042 19.9 0.1 2.1 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EMC83769.1 - 6.6e-05 23.4 0.1 8e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC83769.1 - 0.00034 20.8 0.4 0.00074 19.8 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC83769.1 - 0.00094 19.0 0.7 0.0013 18.6 0.5 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC83769.1 - 0.00096 19.2 0.5 0.0012 18.8 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMC83769.1 - 0.0011 18.5 2.8 0.0024 17.5 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC83769.1 - 0.0016 18.9 0.0 0.01 16.3 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC83769.1 - 0.0016 18.2 4.9 0.19 11.6 0.9 2.2 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EMC83769.1 - 0.0031 17.8 0.2 0.0038 17.5 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC83769.1 - 0.0091 16.1 0.2 0.023 14.8 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EMC83769.1 - 0.078 12.0 0.1 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC83769.1 - 0.1 12.5 1.5 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Med6 PF04934.9 EMC83770.1 - 1e-44 151.4 0.2 1.4e-44 151.0 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Peptidase_M15 PF01427.12 EMC83770.1 - 0.021 14.4 0.1 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase Reprolysin PF01421.14 EMC83771.1 - 1.5e-53 181.3 0.1 1.5e-53 181.3 0.1 2.4 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC83771.1 - 2.5e-35 121.0 2.7 2.5e-35 121.0 1.9 4.1 4 1 0 4 4 4 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 EMC83771.1 - 5.7e-27 94.0 0.0 1.7e-26 92.5 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Disintegrin PF00200.18 EMC83771.1 - 8.9e-23 80.3 22.8 8.9e-23 80.3 15.8 4.2 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 EMC83771.1 - 1.5e-17 64.3 0.0 2.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC83771.1 - 1.5e-17 64.1 0.1 3.8e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMC83771.1 - 9e-15 54.7 0.1 2.7e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC83771.1 - 1.8e-14 54.1 0.2 1.6e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC83771.1 - 0.0055 16.4 0.1 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 EMC83771.1 - 0.021 14.4 1.1 0.021 14.4 0.8 1.6 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A PDZ PF00595.19 EMC83772.1 - 2.1e-20 72.6 0.0 3.4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC83772.1 - 3.5e-08 33.2 0.0 4.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 EMC83772.1 - 0.055 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF3681 PF12442.3 EMC83772.1 - 0.084 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) Peptidase_C97 PF05903.9 EMC83773.1 - 4.8e-41 140.0 0.0 5.8e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3670 PF12419.3 EMC83773.1 - 0.11 11.9 0.1 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 SNF2 Helicase protein LRAT PF04970.8 EMC83773.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Calx-beta PF03160.9 EMC83775.1 - 1.8e-62 207.5 8.6 9.3e-31 105.7 0.1 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex PF01699.19 EMC83775.1 - 2.3e-59 199.0 26.9 1.2e-34 118.9 5.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1735 PF08522.5 EMC83775.1 - 0.089 13.1 2.0 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1735) Acyl_transf_3 PF01757.17 EMC83775.1 - 0.22 10.3 25.9 0.1 11.4 8.2 2.5 2 0 0 2 2 2 0 Acyltransferase family Phage_XkdX PF09693.5 EMC83775.1 - 0.31 10.5 3.5 0.68 9.4 2.4 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Thyroglobulin_1 PF00086.13 EMC83776.1 - 2.3e-21 74.9 14.0 1e-13 50.4 1.6 2.5 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 EMC83776.1 - 6.1e-14 52.0 0.0 1.1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.1 EMC83776.1 - 0.0013 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC83776.1 - 0.0053 16.5 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EMC83776.1 - 0.012 14.8 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 EF hand DUF1977 PF09320.6 EMC83776.1 - 0.056 13.6 0.2 0.056 13.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) EF-hand_5 PF13202.1 EMC83776.1 - 0.083 12.2 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 EF hand Cys_rich_CWC PF14375.1 EMC83776.1 - 0.33 10.8 5.1 3.6 7.5 0.1 2.7 2 0 0 2 2 2 0 Cysteine-rich CWC Defensin_beta PF00711.14 EMC83776.1 - 3.6 7.6 7.5 7.8 6.5 0.7 2.6 2 0 0 2 2 2 0 Beta defensin Laminin_EGF PF00053.19 EMC83776.1 - 7.2 6.6 9.4 2.5 8.0 0.5 2.9 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) SBF PF01758.11 EMC83777.1 - 5.9e-38 130.1 16.9 5.9e-38 130.1 11.7 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.13 EMC83777.1 - 0.012 13.9 17.2 0.044 12.0 5.8 2.5 1 1 0 2 2 2 0 Membrane transport protein DUF1270 PF06900.6 EMC83777.1 - 0.31 11.2 0.3 0.31 11.2 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) DUF204 PF02659.10 EMC83777.1 - 6.4 6.9 16.2 0.35 11.0 0.6 3.5 3 2 1 4 4 4 0 Domain of unknown function DUF RRM_1 PF00076.17 EMC83778.1 - 1.8e-31 107.5 0.1 2.1e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC83778.1 - 5.4e-22 77.5 0.0 1.3e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC83778.1 - 1.9e-12 46.8 0.0 2e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC83778.1 - 1.3e-07 31.4 0.1 0.00097 18.9 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EMC83778.1 - 0.0017 18.0 0.0 0.0048 16.6 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 EMC83778.1 - 0.028 14.0 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.6 EMC83778.1 - 0.77 9.3 3.1 0.47 9.9 0.3 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain CDC45 PF02724.9 EMC83778.1 - 1.3 7.0 8.5 1.6 6.6 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SOG2 PF10428.4 EMC83778.1 - 2.8 6.4 17.3 4.5 5.8 12.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CytochromB561_N PF09786.4 EMC83778.1 - 2.9 6.2 12.6 3.3 6.0 8.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 EMC83778.1 - 3.3 5.8 16.4 3.7 5.6 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Sushi PF00084.15 EMC83779.1 - 3.5e-09 36.8 6.5 5.9e-09 36.1 4.5 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) RSN1_TM PF13967.1 EMC83779.1 - 0.16 11.4 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport PH PF00169.24 EMC83780.1 - 1.4e-05 25.2 0.5 4.6e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 PH domain ERM PF00769.14 EMC83780.1 - 0.0011 18.6 29.4 0.0011 18.6 20.4 2.3 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Myosin_tail_1 PF01576.14 EMC83780.1 - 0.0088 13.8 59.1 0.017 12.9 17.3 2.0 2 0 0 2 2 2 2 Myosin tail Reo_sigmaC PF04582.7 EMC83780.1 - 0.01 15.0 6.1 0.22 10.6 0.3 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein EIF_2_alpha PF07541.7 EMC83780.1 - 2.1 8.0 5.6 0.49 10.1 0.8 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit DUF3726 PF12525.3 EMC83780.1 - 8.6 6.2 9.0 2 8.2 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3726) Zip PF02535.17 EMC83781.1 - 6.3e-41 140.4 21.6 4.5e-32 111.3 7.6 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter ABC2_membrane_5 PF13346.1 EMC83781.1 - 0.065 12.5 3.2 4.4 6.5 0.1 3.2 2 1 1 3 3 3 0 ABC-2 family transporter protein Acyl_transf_3 PF01757.17 EMC83781.1 - 0.47 9.2 5.1 2.5 6.8 1.8 2.5 1 1 1 2 2 2 0 Acyltransferase family Cyto_ox_2 PF02322.10 EMC83781.1 - 2.8 7.0 10.9 1.3 8.1 5.2 2.0 2 1 0 2 2 2 0 Cytochrome oxidase subunit II 7TM-7TMR_HD PF07698.6 EMC83781.1 - 6 6.2 15.1 0.071 12.5 2.2 2.7 3 1 0 3 3 3 0 7TM receptor with intracellular HD hydrolase ER PF01133.12 EMC83782.1 - 5.4e-52 173.8 0.4 6e-52 173.6 0.3 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary DUF3407 PF11887.3 EMC83782.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Glycos_transf_2 PF00535.21 EMC83783.1 - 4.1e-23 81.9 0.0 6.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC83783.1 - 3.8e-17 62.4 3.8 7.3e-17 61.5 2.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.4 EMC83783.1 - 5.2e-10 38.8 0.0 1.5e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EMC83783.1 - 7.1e-10 39.0 0.0 9.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC83783.1 - 1.4e-08 34.1 0.1 2.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4227 PF14004.1 EMC83783.1 - 0.0087 15.8 0.3 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4227) DNA_pol_A_exo1 PF01612.15 EMC83784.1 - 4.4e-17 62.1 0.0 8.6e-17 61.1 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DUF968 PF06147.6 EMC83784.1 - 0.089 12.6 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) WD40 PF00400.27 EMC83785.1 - 5.4e-20 70.4 10.4 3.6e-05 23.4 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Spectrin PF00435.16 EMC83786.1 - 1.4e-76 253.5 25.5 5.2e-27 94.1 4.9 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 EMC83786.1 - 1.6e-40 137.5 0.0 3.1e-21 75.4 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EMC83786.1 - 4.9e-26 90.4 0.0 1.9e-25 88.5 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EMC83786.1 - 2.1e-12 46.4 0.0 9.4e-10 38.0 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.27 EMC83786.1 - 5.7e-10 37.7 0.0 2.1e-05 23.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EMC83786.1 - 2.2e-08 33.2 0.2 5.9e-05 22.6 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EMC83786.1 - 5.1e-07 29.7 0.1 4.2e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC83786.1 - 1.2e-06 27.9 0.3 0.0019 17.7 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC83786.1 - 0.00089 18.4 0.0 0.0061 15.8 0.0 2.4 2 0 0 2 2 2 1 EF hand XisI PF08869.6 EMC83786.1 - 0.0087 16.1 0.9 0.034 14.2 0.6 2.0 1 0 0 1 1 1 1 XisI protein Phage_int_SAM_5 PF13102.1 EMC83786.1 - 0.17 11.9 3.8 0.19 11.7 0.1 3.0 3 0 0 3 3 3 0 Phage integrase SAM-like domain RRM_1 PF00076.17 EMC83787.1 - 2.2e-34 116.9 0.1 9.9e-17 60.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC83787.1 - 3.9e-23 81.2 0.1 5.1e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC83787.1 - 1.9e-15 56.4 0.1 2.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC83787.1 - 2.5e-08 33.7 0.3 6.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EMC83787.1 - 0.04 13.7 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EMC83787.1 - 0.042 13.3 0.1 0.2 11.1 0.1 2.2 1 0 0 1 1 1 0 Ribonuclease B OB domain DbpA PF03880.10 EMC83787.1 - 0.076 12.6 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain Cas_Cas2CT1978 PF09707.5 EMC83787.1 - 0.14 12.1 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) CDC45 PF02724.9 EMC83787.1 - 4.2 5.2 14.0 5.4 4.9 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Gag_spuma PF03276.9 EMC83787.1 - 5 5.3 12.8 6.9 4.8 8.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Rad51 PF08423.6 EMC83788.1 - 4.6e-30 104.3 0.0 5.8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMC83788.1 - 2.3e-14 53.2 0.0 2.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EMC83788.1 - 7e-08 31.8 0.2 1.8e-07 30.5 0.1 1.7 1 1 0 1 1 1 1 KaiC RecA PF00154.16 EMC83788.1 - 2e-05 23.8 0.1 0.012 14.6 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein PAXNEB PF05625.6 EMC83788.1 - 0.0011 17.9 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 PAXNEB protein DnaB_C PF03796.10 EMC83788.1 - 0.0011 17.9 0.1 0.03 13.1 0.1 2.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain SAM_2 PF07647.12 EMC83788.1 - 0.016 15.0 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA PF00004.24 EMC83788.1 - 0.087 13.0 0.0 0.39 10.9 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1113 PF06541.6 EMC83789.1 - 1.2e-10 41.3 11.6 1.5e-10 41.0 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1113) PIG-H PF10181.4 EMC83790.1 - 4.9e-09 35.7 0.1 7.4e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component MNHE PF01899.11 EMC83790.1 - 0.11 12.1 0.3 0.14 11.7 0.2 1.1 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Arginase PF00491.16 EMC83791.1 - 3.1e-69 233.3 0.0 3.7e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Ubiq_cyt_C_chap PF03981.7 EMC83791.1 - 0.099 12.4 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone V-SNARE_C PF12352.3 EMC83792.1 - 6e-20 71.0 8.4 6e-20 71.0 5.8 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EMC83792.1 - 5.7e-13 48.8 4.7 5.7e-13 48.8 3.2 2.2 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 EMC83792.1 - 2.1e-06 27.3 1.7 2.1e-06 27.3 1.2 1.9 2 1 0 2 2 2 1 Sec20 SNARE PF05739.14 EMC83792.1 - 0.00062 19.4 0.7 0.00062 19.4 0.5 2.1 2 1 0 2 2 2 1 SNARE domain Laminin_II PF06009.7 EMC83792.1 - 0.013 15.2 1.8 0.091 12.5 0.4 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF912 PF06024.7 EMC83792.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Fusion_gly PF00523.13 EMC83792.1 - 0.1 10.6 3.7 0.079 11.0 1.1 1.7 1 1 1 2 2 2 0 Fusion glycoprotein F0 Prominin PF05478.6 EMC83792.1 - 0.24 8.8 2.6 0.28 8.6 0.7 1.7 2 0 0 2 2 2 0 Prominin DUF745 PF05335.8 EMC83792.1 - 0.6 9.6 4.2 5.5 6.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Snapin_Pallidin PF14712.1 EMC83792.1 - 0.72 10.2 8.4 0.69 10.2 0.2 2.6 2 1 0 2 2 2 0 Snapin/Pallidin Synaptobrevin PF00957.16 EMC83792.1 - 3.2 7.4 6.2 0.69 9.5 1.5 2.0 2 1 0 2 2 2 0 Synaptobrevin CTNNB1_binding PF08347.6 EMC83792.1 - 8.7 6.5 7.6 1.5 9.0 0.9 2.2 1 1 1 2 2 2 0 N-terminal CTNNB1 binding FYVE PF01363.16 EMC83793.1 - 5.3e-16 58.2 15.6 5.3e-16 58.2 10.8 2.7 3 0 0 3 3 3 1 FYVE zinc finger TPR_2 PF07719.12 EMC83793.1 - 0.0023 17.7 1.4 0.025 14.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC83793.1 - 0.12 13.1 3.1 80 4.2 0.0 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Gal-bind_lectin PF00337.17 EMC83794.1 - 1.1e-30 105.6 0.0 1.3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin PH PF00169.24 EMC83795.1 - 9.1e-34 115.7 0.0 1.9e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 PH domain DEP PF00610.16 EMC83795.1 - 2.2e-16 59.3 0.0 5.6e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_11 PF15413.1 EMC83795.1 - 1.5e-11 44.5 5.6 2.2e-05 24.6 0.1 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EMC83795.1 - 1.2e-07 31.8 0.5 0.034 14.3 0.0 3.4 3 2 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 EMC83795.1 - 0.00035 20.5 0.3 0.19 11.8 0.2 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 EMC83795.1 - 0.012 15.7 0.0 0.38 10.8 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain PH_4 PF15404.1 EMC83795.1 - 0.021 14.3 1.0 15 5.0 0.0 3.7 4 0 0 4 4 4 0 Pleckstrin homology domain EIF_2_alpha PF07541.7 EMC83796.1 - 2.1e-37 127.2 0.0 4.4e-37 126.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EMC83796.1 - 3e-15 56.0 0.7 7.4e-15 54.7 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Herpes_BLRF2 PF05812.7 EMC83796.1 - 0.11 12.2 1.6 6 6.7 0.0 2.7 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein ATP-synt_D PF01813.12 EMC83797.1 - 9.9e-67 224.2 8.6 1.2e-66 223.9 6.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Guanylate_kin PF00625.16 EMC83798.1 - 2.8e-51 173.5 0.0 6.6e-51 172.3 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase L27_N PF09060.5 EMC83798.1 - 7.2e-25 86.5 2.4 1.7e-24 85.3 1.7 1.7 1 0 0 1 1 1 1 L27_N SH3_2 PF07653.12 EMC83798.1 - 1.5e-12 46.8 0.0 3.6e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.19 EMC83798.1 - 3.8e-12 46.2 0.4 8.6e-12 45.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 EMC83798.1 - 5.2e-09 35.6 1.2 1.7e-08 34.0 0.9 1.8 1 0 0 1 1 1 1 L27 domain SH3_1 PF00018.23 EMC83798.1 - 9.6e-07 28.1 0.3 3.2e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.1 EMC83798.1 - 1.9e-06 27.6 0.1 6.4e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.1 EMC83798.1 - 2.5e-05 23.7 0.1 5.8e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.18 EMC83798.1 - 0.039 13.9 0.0 0.75 9.7 0.0 3.1 2 1 1 3 3 3 0 50S ribosome-binding GTPase MoCF_biosynth PF00994.19 EMC83799.1 - 4e-68 227.3 0.0 8.7e-38 128.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EMC83799.1 - 6e-50 168.7 1.6 6.6e-50 168.6 0.2 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EMC83799.1 - 4.1e-23 81.1 0.0 1.1e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) BMF PF15185.1 EMC83800.1 - 6.8e-65 218.4 7.5 2.4e-64 216.6 5.2 1.7 1 1 0 1 1 1 1 Bcl-2-modifying factor, apoptosis SRP14 PF02290.10 EMC83801.1 - 8.6e-32 108.9 0.1 8.6e-32 108.9 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Pkinase PF00069.20 EMC83802.1 - 1.3e-77 260.5 15.0 8.1e-39 133.3 0.0 5.4 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMC83802.1 - 4.1e-46 157.1 5.8 6.2e-19 68.0 0.2 4.7 4 2 0 4 4 4 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EMC83802.1 - 1.3e-15 57.2 0.9 2.1e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 EMC83802.1 - 1.1e-13 51.0 0.0 6.2e-13 48.6 0.0 2.5 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 EMC83802.1 - 5.3e-13 48.7 0.8 5.3e-13 48.7 0.5 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Kinase-like PF14531.1 EMC83802.1 - 9.5e-07 28.0 0.0 0.035 13.0 0.0 2.7 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMC83802.1 - 5.6e-05 22.2 0.2 0.029 13.4 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC83802.1 - 0.004 16.9 0.1 0.036 13.7 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Borrelia_P83 PF05262.6 EMC83802.1 - 2.1 6.5 13.5 3.5 5.8 9.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1682 PF07946.9 EMC83802.1 - 4.5 6.0 24.2 2.8 6.6 15.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) 7tm_1 PF00001.16 EMC83803.1 - 1.7e-30 106.0 29.1 2.2e-30 105.6 20.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4083 PF13314.1 EMC83803.1 - 0.15 11.9 3.5 0.63 9.9 2.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) FSIP1 PF15554.1 EMC83804.1 - 1.1e-16 60.6 3.7 1.3e-16 60.5 2.6 1.0 1 0 0 1 1 1 1 FSIP1 family Katanin_con80 PF13925.1 EMC83806.1 - 9.3e-33 113.2 0.1 1.9e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 con80 domain of Katanin DUF2012 PF09430.5 EMC83807.1 - 6.6e-30 103.4 0.1 8.7e-30 103.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EMC83807.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Fibrinogen_C PF00147.13 EMC83808.1 - 5.8e-41 140.6 3.2 6.4e-41 140.4 2.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CopB PF05275.6 EMC83808.1 - 0.072 12.3 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) 7tm_1 PF00001.16 EMC83809.1 - 2.5e-86 289.0 6.9 3.4e-86 288.5 4.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC83809.1 - 2.9e-07 29.8 6.2 2.9e-07 29.8 4.3 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 EMC83809.1 - 4.4e-06 26.0 3.8 4.4e-06 26.0 2.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx FH2 PF02181.18 EMC83812.1 - 5.7e-102 341.3 7.0 5.7e-102 341.3 4.9 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain RNA_pol_Rpb1_5 PF04998.12 EMC83812.1 - 0.0029 16.9 0.0 0.018 14.3 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 DAN PF03045.10 EMC83813.1 - 4.8e-38 129.3 5.7 6.4e-38 128.9 3.9 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 EMC83813.1 - 0.0027 17.7 4.9 0.0041 17.1 3.4 1.2 1 0 0 1 1 1 1 Cystine-knot domain DUF2602 PF10782.4 EMC83813.1 - 1.8 8.4 8.0 5.8 6.8 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2602) Secretogranin_V PF05281.6 EMC83814.1 - 2.9e-69 232.6 4.3 4.8e-68 228.6 3.0 1.9 1 1 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) RhoGAP PF00620.22 EMC83815.1 - 3.4e-30 104.6 0.1 7e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain TPD PF14811.1 EMC83816.1 - 2.4e-35 121.0 2.6 1.2e-34 118.7 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function TPD sequence-motif ATP_bind_4 PF01902.12 EMC83818.1 - 5.5e-43 146.8 0.1 1.3e-42 145.6 0.0 1.5 1 1 0 1 1 1 1 ATP-binding region zf-C2H2 PF00096.21 EMC83819.1 - 2.7e-38 128.0 119.2 2.5e-05 24.3 1.4 13.4 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83819.1 - 1e-30 103.7 110.5 6.6e-05 22.9 1.0 13.5 13 0 0 13 13 13 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC83819.1 - 1.2e-25 88.4 127.2 2.3e-07 30.7 0.9 14.6 16 1 0 16 16 16 11 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMC83819.1 - 2.7e-09 36.6 73.6 0.46 10.4 0.2 13.0 13 0 0 13 13 13 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC83819.1 - 3.6e-07 30.1 67.0 0.099 12.8 0.2 12.9 13 0 0 13 13 13 6 Zinc-finger double-stranded RNA-binding BolA PF01722.13 EMC83819.1 - 7.8e-05 22.5 12.8 2.7 7.9 0.0 6.7 5 3 2 7 7 7 3 BolA-like protein FYDLN_acid PF09538.5 EMC83819.1 - 0.0079 16.7 8.1 33 5.0 0.1 6.5 6 1 0 6 6 6 0 Protein of unknown function (FYDLN_acid) zf-C2HC_2 PF13913.1 EMC83819.1 - 0.14 11.8 0.1 0.14 11.8 0.1 9.9 10 0 0 10 10 10 0 zinc-finger of a C2HC-type zf-met PF12874.2 EMC83819.1 - 0.26 11.5 77.6 0.49 10.6 0.4 12.7 13 0 0 13 13 13 0 Zinc-finger of C2H2 type zf-CCHC_2 PF13696.1 EMC83819.1 - 5.7 6.5 13.6 5.8 6.4 0.3 4.2 3 0 0 3 3 3 0 Zinc knuckle AAA_11 PF13086.1 EMC83820.1 - 3.4e-27 95.5 0.0 1.2e-26 93.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EMC83820.1 - 2.2e-26 92.4 1.3 7.7e-25 87.4 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EMC83820.1 - 5.9e-08 32.3 0.0 2.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EMC83820.1 - 0.0017 18.2 0.0 0.0057 16.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMC83820.1 - 0.0071 15.9 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMC83820.1 - 0.0093 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EMC83820.1 - 0.0098 14.8 0.2 0.11 11.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EMC83820.1 - 0.04 13.4 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EMC83820.1 - 0.07 13.2 0.7 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain RecA PF00154.16 EMC83820.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Actin PF00022.14 EMC83821.1 - 7.9e-154 511.8 0.0 8.8e-154 511.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EMC83821.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Connexin PF00029.14 EMC83822.1 - 2.5e-45 152.9 2.8 2.5e-45 152.9 2.0 1.7 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 EMC83822.1 - 1.5e-31 108.0 2.4 1.5e-31 108.0 1.7 2.3 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain DIRP PF06584.8 EMC83822.1 - 0.037 13.9 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 DIRP Sec3-PIP2_bind PF15277.1 EMC83823.1 - 5.3e-27 93.5 0.1 1e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.16 EMC83823.1 - 2.3e-06 27.1 0.5 2.3e-06 27.1 0.4 1.8 2 0 0 2 2 2 1 Synaptobrevin KH_1 PF00013.24 EMC83824.1 - 2.2e-32 110.4 5.4 2.4e-16 59.1 0.4 2.6 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 EMC83824.1 - 1.4e-23 82.0 1.6 4.7e-11 42.0 0.0 2.9 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 EMC83824.1 - 1.4e-08 34.1 3.7 2.4e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EMC83824.1 - 4.2e-07 29.5 1.7 0.0049 16.4 0.0 2.9 3 0 0 3 3 3 2 KH domain dUTPase PF00692.14 EMC83824.1 - 0.039 13.4 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 dUTPase KH_5 PF13184.1 EMC83824.1 - 0.11 12.3 0.8 0.97 9.2 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain PAP1 PF08601.5 EMC83824.1 - 0.15 11.6 0.3 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Fork_head PF00250.13 EMC83826.1 - 3e-45 152.2 0.0 5.5e-45 151.3 0.0 1.4 1 0 0 1 1 1 1 Fork head domain zf-HC5HC2H PF13771.1 EMC83827.1 - 3.4e-20 71.9 2.7 3.4e-20 71.9 1.9 3.9 2 1 1 3 3 3 1 PHD-like zinc-binding domain HECT PF00632.20 EMC83827.1 - 2.3e-14 53.2 0.1 5e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-HC5HC2H_2 PF13832.1 EMC83827.1 - 2.4e-07 30.7 4.6 2.4e-07 30.7 3.2 4.0 2 1 2 4 4 4 1 PHD-zinc-finger like domain Sec1 PF00995.18 EMC83828.1 - 2.5e-150 501.8 0.6 2.8e-150 501.6 0.4 1.0 1 0 0 1 1 1 1 Sec1 family cwf21 PF08312.7 EMC83828.1 - 0.019 14.8 0.0 0.3 10.9 0.0 2.7 3 0 0 3 3 3 0 cwf21 domain VWA PF00092.23 EMC83829.1 - 8.9e-81 269.8 0.6 4.6e-42 143.7 0.2 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.14 EMC83829.1 - 4.2e-22 77.9 0.0 9.5e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 LCCL domain VWA_2 PF13519.1 EMC83829.1 - 1.9e-16 60.6 0.0 7.4e-11 42.4 0.1 2.3 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 EMC83829.1 - 0.0021 17.7 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Clat_adaptor_s PF01217.15 EMC83830.1 - 2e-38 131.2 7.8 2.3e-38 131.1 5.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HECT PF00632.20 EMC83831.1 - 5.8e-85 285.2 0.0 1.1e-84 284.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.8 EMC83831.1 - 3.1e-24 84.7 3.9 7.9e-24 83.4 2.7 1.8 1 0 0 1 1 1 1 Mib_herc2 Sad1_UNC PF07738.8 EMC83831.1 - 7.2e-24 84.1 0.0 1.4e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ank_2 PF12796.2 EMC83831.1 - 4.8e-17 62.0 0.0 2.1e-16 60.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC83831.1 - 4.6e-16 57.7 0.0 9.9e-06 25.1 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMC83831.1 - 1.7e-12 47.1 0.0 5.4e-09 36.0 0.0 3.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC83831.1 - 1.4e-10 41.4 0.0 3.5e-07 30.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC83831.1 - 4.1e-09 35.8 0.0 0.0081 16.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat F5_F8_type_C PF00754.20 EMC83831.1 - 2e-05 24.4 0.1 6.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 F5/8 type C domain HEAT_2 PF13646.1 EMC83832.1 - 1.3e-12 47.8 16.5 0.19 11.9 0.1 10.1 8 3 1 9 9 9 4 HEAT repeats HEAT PF02985.17 EMC83832.1 - 3.3e-08 32.9 35.0 0.016 15.2 0.3 11.9 12 0 0 12 12 12 5 HEAT repeat Vac14_Fab1_bd PF12755.2 EMC83832.1 - 0.00037 20.8 0.0 0.011 16.0 0.0 3.5 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC83832.1 - 0.03 14.8 36.8 0.16 12.4 0.2 10.0 10 1 0 10 10 10 0 HEAT-like repeat Tyr_Deacylase PF02580.11 EMC83833.1 - 1.7e-38 131.8 0.0 1.9e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase ParA PF10609.4 EMC83834.1 - 1.4e-37 127.4 0.5 7.6e-37 125.0 0.1 2.0 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EMC83834.1 - 2.9e-11 43.1 1.9 7.9e-06 25.4 0.7 2.1 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMC83834.1 - 2.6e-05 24.2 0.0 0.0017 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EMC83834.1 - 4.3e-05 22.7 0.9 0.00028 20.0 0.3 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EMC83834.1 - 8.2e-05 21.7 0.9 0.0012 17.9 0.3 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EMC83834.1 - 0.0005 19.3 0.1 0.0048 16.1 0.0 2.1 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 EMC83834.1 - 0.0059 16.3 0.3 0.21 11.3 0.3 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EMC83834.1 - 0.0091 15.4 0.4 0.02 14.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC83834.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RhoGAP PF00620.22 EMC83835.1 - 4.9e-48 162.5 0.7 9.7e-48 161.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Ras PF00071.17 EMC83835.1 - 5e-14 51.9 3.9 3.5e-05 23.2 0.2 4.5 4 0 0 4 4 4 4 Ras family FF PF01846.14 EMC83835.1 - 6.7e-14 51.5 17.0 1.4e-09 37.7 0.8 4.7 5 0 0 5 5 5 3 FF domain AAA_22 PF13401.1 EMC83835.1 - 0.0017 18.4 0.3 2.7 8.1 0.2 3.2 2 1 0 2 2 2 2 AAA domain GTP_EFTU PF00009.22 EMC83835.1 - 0.0027 17.1 0.2 0.008 15.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Spectrin PF00435.16 EMC83836.1 - 5.6e-09 36.2 32.9 2.4e-05 24.5 2.4 6.4 6 1 0 6 6 6 3 Spectrin repeat 7tm_7 PF08395.7 EMC83836.1 - 0.017 14.1 3.5 0.16 10.9 0.0 2.3 2 0 0 2 2 2 0 7tm Chemosensory receptor Tetraspannin PF00335.15 EMC83836.1 - 3.9 6.6 5.0 4 6.6 0.4 2.5 2 0 0 2 2 2 0 Tetraspanin family HLH PF00010.21 EMC83837.1 - 1.8e-05 24.3 0.6 2.3e-05 23.9 0.4 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Eapp_C PF10238.4 EMC83838.1 - 3.4e-50 169.4 8.7 3.4e-50 169.4 6.0 1.8 2 1 1 3 3 3 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 EMC83838.1 - 0.0077 16.2 6.1 0.02 14.9 4.2 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly IBR PF01485.16 EMC83838.1 - 0.018 14.9 1.2 0.092 12.6 0.1 2.3 2 0 0 2 2 2 0 IBR domain C1_4 PF07975.7 EMC83838.1 - 0.034 14.1 3.6 0.056 13.4 0.3 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain DUF2489 PF10675.4 EMC83838.1 - 0.038 13.6 0.7 0.038 13.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) YMF19 PF02326.10 EMC83838.1 - 0.43 11.1 1.9 0.58 10.7 0.3 2.0 2 0 0 2 2 2 0 Plant ATP synthase F0 Vps5 PF09325.5 EMC83840.1 - 2.4e-17 62.9 14.7 7e-12 45.1 3.3 2.8 2 1 1 3 3 3 2 Vps5 C terminal like PX PF00787.19 EMC83840.1 - 2e-15 56.5 0.7 2.4e-13 49.8 0.0 3.2 3 0 0 3 3 3 1 PX domain BAR PF03114.13 EMC83840.1 - 1.8e-09 37.4 15.6 2.3e-07 30.5 6.3 2.9 3 0 0 3 3 3 2 BAR domain DUF1825 PF08855.5 EMC83840.1 - 0.067 13.1 2.1 0.11 12.4 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) Cofilin_ADF PF00241.15 EMC83842.1 - 4.4e-38 130.0 0.6 5.3e-38 129.7 0.4 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Methyltransf_26 PF13659.1 EMC83843.1 - 1.6e-07 31.3 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC83843.1 - 9.8e-07 29.3 0.1 2.4e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC83843.1 - 5.8e-05 23.5 0.3 0.00016 22.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EMC83843.1 - 8.4e-05 21.9 0.1 0.00012 21.3 0.1 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.7 EMC83843.1 - 0.00012 22.4 0.0 0.00024 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC83843.1 - 0.00023 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC83843.1 - 0.0006 20.1 1.2 0.00093 19.5 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EMC83843.1 - 0.017 14.7 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.8 EMC83843.1 - 0.019 14.3 1.7 0.21 10.8 1.0 2.3 1 1 0 1 1 1 0 Histone methylation protein DOT1 SRP54 PF00448.17 EMC83844.1 - 6.6e-78 260.6 0.5 4.9e-77 257.8 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EMC83844.1 - 1.2e-26 93.0 3.3 1.2e-26 93.0 2.3 3.1 2 1 1 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 EMC83844.1 - 1.9e-17 63.1 2.8 5.2e-17 61.7 1.9 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain FAM177 PF14774.1 EMC83844.1 - 6.6e-10 38.9 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 FAM177 family cobW PF02492.14 EMC83844.1 - 5.3e-08 32.5 0.6 2.3e-07 30.4 0.2 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMC83844.1 - 1.3e-06 28.3 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EMC83844.1 - 7.5e-06 25.7 0.0 2.7e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2209 PF09974.4 EMC83844.1 - 8.6e-06 25.8 0.3 2.6e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) CbiA PF01656.18 EMC83844.1 - 1.2e-05 24.7 0.1 5.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.5 EMC83844.1 - 0.0002 20.6 0.5 0.55 9.4 0.0 2.7 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_31 PF13614.1 EMC83844.1 - 0.0002 21.2 0.1 0.39 10.6 0.0 3.3 3 1 1 4 4 3 1 AAA domain AAA_17 PF13207.1 EMC83844.1 - 0.00034 21.4 0.0 0.0011 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC83844.1 - 0.0017 18.5 0.6 0.0083 16.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EMC83844.1 - 0.0017 17.1 0.0 0.032 13.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 EMC83844.1 - 0.0019 18.1 0.3 0.0073 16.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EMC83844.1 - 0.0038 16.9 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EMC83844.1 - 0.0039 16.6 0.1 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 EMC83844.1 - 0.0076 15.8 0.1 0.023 14.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EMC83844.1 - 0.014 15.6 0.1 0.062 13.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EMC83844.1 - 0.025 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.13 EMC83844.1 - 0.029 13.4 0.0 0.072 12.1 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 EMC83844.1 - 0.036 14.0 0.0 0.13 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EMC83844.1 - 0.037 13.5 2.0 0.16 11.4 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EMC83844.1 - 0.038 13.0 0.0 0.081 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 EMC83844.1 - 0.051 13.0 0.6 1 8.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation VirE PF05272.6 EMC83844.1 - 0.086 12.3 0.1 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E AAA_28 PF13521.1 EMC83844.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMC83844.1 - 0.21 11.8 1.5 2.4 8.4 1.0 2.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMC83844.1 - 0.34 11.1 4.7 0.45 10.7 0.1 3.2 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) EF-hand_7 PF13499.1 EMC83845.1 - 1.1e-10 41.4 6.9 1.6e-06 28.1 1.0 4.6 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC83845.1 - 5.7e-06 25.7 4.3 1.1 9.2 0.0 5.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EMC83845.1 - 3.1e-05 22.9 0.1 0.17 11.2 0.0 4.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EMC83845.1 - 0.0014 18.1 0.1 2.2 7.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC83845.1 - 0.022 14.0 0.2 0.21 10.9 0.0 2.7 2 0 0 2 2 2 0 EF hand PPR_3 PF13812.1 EMC83846.1 - 2.3e-08 33.6 0.2 0.0059 16.8 0.0 3.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EMC83846.1 - 1.8e-07 31.0 0.1 0.14 12.1 0.0 3.9 2 1 1 3 3 3 2 PPR repeat family RNase_Zc3h12a PF11977.3 EMC83846.1 - 1.7e-06 27.9 0.0 6.8e-06 25.9 0.0 1.9 1 1 1 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain PPR PF01535.15 EMC83846.1 - 5.5e-06 25.9 6.5 0.051 13.5 0.0 4.8 5 0 0 5 5 5 2 PPR repeat Rad50_zn_hook PF04423.9 EMC83846.1 - 0.072 12.5 0.4 0.37 10.3 0.2 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Proteasome PF00227.21 EMC83847.1 - 5.8e-53 179.0 0.2 6.7e-53 178.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Ank PF00023.25 EMC83848.1 - 2.5e-37 124.8 9.4 3.7e-10 39.0 0.2 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EMC83848.1 - 2.1e-33 114.5 3.2 1.6e-17 63.5 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC83848.1 - 4.1e-28 96.7 8.0 8.7e-11 41.7 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC83848.1 - 1.2e-27 93.1 6.1 5.2e-07 29.2 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EMC83848.1 - 1.2e-22 79.7 1.6 1.1e-10 41.6 0.2 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EMC83848.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.6 2 0 0 2 2 2 0 Shigella flexneri OspC protein DUF3571 PF12095.3 EMC83848.1 - 0.037 14.2 0.4 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) Imm29 PF15575.1 EMC83848.1 - 0.099 12.2 0.0 6.1 6.3 0.0 2.6 1 1 0 2 2 2 0 Immunity protein 29 Rap_GAP PF02145.10 EMC83849.1 - 1.5e-64 216.8 0.0 2.7e-64 216.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP DUF624 PF04854.9 EMC83849.1 - 0.51 10.2 2.1 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Sds3 PF08598.6 EMC83850.1 - 1.2e-45 155.6 8.7 2.3e-45 154.6 6.0 1.5 1 1 0 1 1 1 1 Sds3-like ING PF12998.2 EMC83850.1 - 0.035 14.3 3.8 0.26 11.5 2.6 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Borrelia_P83 PF05262.6 EMC83850.1 - 0.17 10.0 5.7 0.24 9.6 3.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AATF-Che1 PF13339.1 EMC83850.1 - 0.46 10.6 5.1 0.33 11.1 0.2 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF16 PF01519.11 EMC83850.1 - 1.2 9.3 5.8 3.9 7.7 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 TruD PF01142.13 EMC83851.1 - 0.0019 16.9 0.0 0.0027 16.4 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Sdh5 PF03937.11 EMC83851.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Homeobox PF00046.24 EMC83852.1 - 5e-21 74.0 4.6 8.9e-21 73.2 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Adhesin_P1 PF03257.8 EMC83852.1 - 5.9 7.2 11.8 2.1 8.7 5.7 2.2 2 0 0 2 2 2 0 Mycoplasma adhesin P1 PAX PF00292.13 EMC83853.1 - 5.3e-71 236.1 0.2 8.5e-71 235.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 EMC83853.1 - 2.5e-07 30.1 0.1 7.1e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EMC83853.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EMC83853.1 - 0.03 15.0 0.0 0.1 13.3 0.0 2.0 1 1 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 EMC83853.1 - 0.13 12.3 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Mito_carr PF00153.22 EMC83854.1 - 1.6e-53 178.3 1.9 1.5e-20 72.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3810 PF12725.2 EMC83855.1 - 9.4 5.0 9.5 3.7 6.3 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) TPR_11 PF13414.1 EMC83856.1 - 2.3e-83 273.8 39.8 8.4e-14 50.9 2.0 10.1 6 3 5 11 11 11 11 TPR repeat TPR_1 PF00515.23 EMC83856.1 - 3e-63 207.0 48.3 3.6e-06 26.3 0.2 16.8 14 3 1 15 15 15 13 Tetratricopeptide repeat TPR_2 PF07719.12 EMC83856.1 - 6.4e-55 178.7 36.7 3.3e-05 23.4 0.0 17.2 17 1 0 17 17 17 13 Tetratricopeptide repeat TPR_17 PF13431.1 EMC83856.1 - 5.3e-38 126.0 23.2 0.00051 20.0 0.8 13.9 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 EMC83856.1 - 6.8e-36 122.1 4.1 1.3e-05 25.7 0.0 11.1 4 3 7 12 12 12 9 Tetratricopeptide repeat TPR_9 PF13371.1 EMC83856.1 - 2e-35 120.4 9.1 1.3e-06 28.0 0.0 9.5 5 3 5 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 EMC83856.1 - 5.6e-31 103.9 34.5 0.00016 21.1 0.7 14.4 12 2 3 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.1 EMC83856.1 - 4.5e-28 97.3 9.1 2.6e-06 27.6 0.0 8.5 6 2 4 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EMC83856.1 - 9.9e-27 92.7 31.3 0.00031 20.6 0.0 10.6 3 2 5 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 EMC83856.1 - 6e-25 85.4 1.0 0.1 13.2 0.0 13.0 6 5 10 16 16 16 6 Tetratricopeptide repeat TPR_6 PF13174.1 EMC83856.1 - 2.4e-14 52.7 26.5 1.4 9.5 0.1 12.7 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC83856.1 - 2.7e-11 42.3 15.5 0.3 10.9 0.0 9.5 10 1 1 11 11 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EMC83856.1 - 1.1e-09 38.3 40.7 0.014 15.4 1.9 8.3 1 1 8 9 9 9 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EMC83856.1 - 1.8e-06 27.2 4.8 8.9 5.2 0.0 6.5 3 2 3 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.3 EMC83856.1 - 1.2e-05 24.2 3.0 0.52 9.0 0.1 5.2 2 2 3 6 6 6 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 EMC83856.1 - 0.00051 19.8 12.1 0.22 11.4 0.0 5.4 6 0 0 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 EMC83856.1 - 0.0013 17.9 10.0 0.18 11.0 0.0 7.9 11 0 0 11 11 11 1 SHNi-TPR TPR_20 PF14561.1 EMC83856.1 - 0.0015 18.6 0.3 12 6.1 0.0 5.5 4 2 2 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC83856.1 - 0.02 14.8 11.8 2.2 8.3 0.0 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF357 PF04010.8 EMC83856.1 - 2.8 7.6 15.7 19 5.0 0.1 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF357) 7tm_1 PF00001.16 EMC83857.1 - 6e-69 232.0 28.1 7.8e-69 231.6 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83857.1 - 4.1e-14 52.3 23.8 5.1e-14 52.0 16.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC83857.1 - 5.6e-09 35.5 14.7 5.6e-09 35.5 10.2 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC83857.1 - 3.4e-06 26.3 23.0 6e-06 25.5 15.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx T2SM PF04612.7 EMC83857.1 - 0.019 14.7 0.8 0.019 14.7 0.5 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4131 PF13567.1 EMC83857.1 - 2 7.7 4.6 29 4.0 3.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) COX7C PF02935.11 EMC83857.1 - 2.7 7.8 6.1 0.46 10.3 0.2 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc 60KD_IMP PF02096.15 EMC83857.1 - 5.7 6.5 13.3 19 4.8 9.2 1.9 1 1 0 1 1 1 0 60Kd inner membrane protein Sec23_trunk PF04811.10 EMC83858.1 - 3.6e-81 272.1 0.0 5.1e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMC83858.1 - 5.6e-35 118.8 0.1 1.1e-34 117.9 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMC83858.1 - 3.1e-33 114.1 0.0 6.9e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EMC83858.1 - 2.9e-15 55.6 0.0 7.9e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 EMC83858.1 - 4.6e-15 54.8 6.4 8.6e-15 54.0 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger APP_E2 PF12925.2 EMC83858.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein AphA_like PF14557.1 EMC83858.1 - 0.2 11.1 0.2 0.36 10.3 0.2 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator SIP1 PF04938.7 EMC83859.1 - 1.1e-106 355.4 0.5 1.3e-106 355.2 0.4 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TRAPP PF04051.11 EMC83860.1 - 1.9e-36 124.8 0.2 2e-36 124.7 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pinin_SDK_memA PF04696.8 EMC83861.1 - 4e-50 168.8 20.3 4e-50 168.8 14.1 4.9 4 2 1 5 5 5 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_N PF04697.8 EMC83861.1 - 3.2e-49 166.4 8.9 3.2e-49 166.4 6.1 3.7 4 1 0 4 4 4 1 pinin/SDK conserved region SH3_2 PF07653.12 EMC83862.1 - 2.2e-10 39.8 0.0 3.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC83862.1 - 0.015 14.8 0.1 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 EMC83862.1 - 0.023 14.0 0.2 0.063 12.6 0.0 1.8 2 1 0 2 2 2 0 SH3 domain DUF4156 PF13698.1 EMC83862.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) NPIP PF06409.6 EMC83863.1 - 0.0001 21.1 9.0 0.0001 21.1 6.2 2.6 3 0 0 3 3 3 1 Nuclear pore complex interacting protein (NPIP) AAA_13 PF13166.1 EMC83863.1 - 0.00021 19.8 26.3 0.00021 19.8 18.2 2.0 2 0 0 2 2 2 2 AAA domain DUF4200 PF13863.1 EMC83863.1 - 0.0026 17.6 12.8 0.0026 17.6 8.9 4.9 2 2 3 5 5 4 1 Domain of unknown function (DUF4200) DUF2935 PF11155.3 EMC83863.1 - 0.033 14.2 0.6 0.033 14.2 0.4 4.6 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) DUF1664 PF07889.7 EMC83863.1 - 0.53 10.0 37.9 0.023 14.4 5.3 4.6 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 EMC83863.1 - 0.58 10.0 86.9 0.16 11.7 16.4 4.5 3 2 0 3 3 3 0 Tropomyosin like Reo_sigmaC PF04582.7 EMC83863.1 - 0.67 9.0 20.6 0.58 9.2 2.3 3.3 2 2 1 3 3 3 0 Reovirus sigma C capsid protein IR1-M PF12185.3 EMC83863.1 - 0.86 9.3 5.5 0.11 12.1 0.2 2.3 2 0 0 2 2 1 0 Nup358/RanBP2 E3 ligase domain IncA PF04156.9 EMC83863.1 - 1.4 8.4 84.6 0.19 11.2 9.4 4.9 2 2 1 3 3 3 0 IncA protein BRCA-2_OB3 PF09104.5 EMC83863.1 - 2.1 8.1 6.7 0.58 9.9 0.5 2.7 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 FAD-SLDH PF12318.3 EMC83863.1 - 2.2 7.9 5.7 8.6 6.0 0.4 2.9 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase MxiH PF09392.5 EMC83863.1 - 3.2 8.4 8.2 1.2 9.7 0.4 3.1 2 1 0 2 2 2 0 Type III secretion needle MxiH like Laminin_I PF06008.9 EMC83863.1 - 5.8 6.1 59.1 0.017 14.4 12.0 2.7 2 1 0 2 2 2 0 Laminin Domain I zf-H2C2_2 PF13465.1 EMC83865.1 - 2.1e-29 100.3 29.6 1.3e-07 31.5 0.2 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC83865.1 - 3.2e-23 80.6 26.3 5e-05 23.3 0.1 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC83865.1 - 2e-15 55.9 24.6 0.0001 22.4 1.9 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC83865.1 - 1.5e-05 24.5 4.2 0.37 10.4 0.0 4.8 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EMC83865.1 - 0.0023 18.0 10.3 0.49 10.6 0.0 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC83865.1 - 0.0046 17.1 9.9 0.61 10.3 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type CHORD PF04968.7 EMC83865.1 - 0.11 12.8 12.3 1.7 8.9 0.0 4.7 2 1 3 5 5 5 0 CHORD zf-C2H2_2 PF12756.2 EMC83865.1 - 0.25 11.4 10.2 0.43 10.7 2.2 3.6 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EMC83865.1 - 8.6 6.4 18.2 0.37 10.7 0.3 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger UPF0564 PF10595.4 EMC83866.1 - 9.7e-73 245.1 40.6 9.7e-73 245.1 28.1 1.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 A1_Propeptide PF07966.7 EMC83866.1 - 0.064 13.0 0.2 0.4 10.5 0.0 2.6 2 0 0 2 2 2 0 A1 Propeptide IGR PF09597.5 EMC83866.1 - 0.21 11.5 3.5 0.47 10.3 1.2 2.4 2 0 0 2 2 2 0 IGR protein motif FAD_binding_3 PF01494.14 EMC83867.1 - 3.5e-19 69.0 0.3 2.4e-10 40.0 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.9 EMC83867.1 - 0.00018 20.2 0.4 0.48 9.0 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase SE PF08491.5 EMC83867.1 - 0.00033 19.5 0.0 0.00073 18.4 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 EMC83867.1 - 0.027 13.3 0.0 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMC83867.1 - 0.05 12.5 0.1 6 5.6 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein GDA1_CD39 PF01150.12 EMC83868.1 - 1.7e-78 264.0 0.0 1.3e-77 261.1 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Aldedh PF00171.17 EMC83869.1 - 3.3e-134 447.7 0.0 3.7e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC83869.1 - 0.013 14.2 0.0 0.027 13.1 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AMP-binding PF00501.23 EMC83870.1 - 4.8e-10 38.4 0.0 6.1e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC83870.1 - 1.3e-09 38.8 1.7 2.2e-09 38.1 1.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_membrane_2 PF06472.10 EMC83871.1 - 2.4e-83 279.5 3.5 3.3e-83 279.0 2.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMC83871.1 - 9.9e-18 64.7 0.0 1.7e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EMC83871.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SbmA_BacA PF05992.7 EMC83871.1 - 0.00087 18.5 2.1 0.0014 17.9 1.4 1.3 1 0 0 1 1 1 1 SbmA/BacA-like family AAA_30 PF13604.1 EMC83871.1 - 0.0016 18.0 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EMC83871.1 - 0.0043 17.0 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IRK PF01007.15 EMC83871.1 - 0.0064 15.3 0.2 0.0094 14.7 0.1 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel Miro PF08477.8 EMC83871.1 - 0.0069 16.8 0.1 0.018 15.5 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 EMC83871.1 - 0.011 16.0 0.1 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMC83871.1 - 0.017 15.2 0.1 0.086 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMC83871.1 - 0.017 14.2 0.3 0.039 13.1 0.1 1.5 2 0 0 2 2 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC83871.1 - 0.037 13.5 0.3 0.08 12.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EMC83871.1 - 0.051 12.9 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.7 EMC83871.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EMC83871.1 - 0.076 12.4 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EMC83871.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EMC83871.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EMC83871.1 - 0.094 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 EMC83871.1 - 0.099 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 EMC83871.1 - 0.11 11.9 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 EMC83871.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EMC83871.1 - 0.14 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EMC83871.1 - 0.16 11.3 0.9 0.36 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMC83871.1 - 0.18 11.7 0.1 0.55 10.2 0.1 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase Dispanin PF04505.7 EMC83872.1 - 6.5e-23 80.0 0.0 1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Fe-S_biosyn PF01521.15 EMC83873.1 - 1.1e-08 34.9 0.0 2.2e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3117 PF11314.3 EMC83873.1 - 0.14 11.6 1.9 0.67 9.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) E1_DerP2_DerF2 PF02221.10 EMC83874.1 - 8.6e-30 103.7 0.5 1e-29 103.4 0.4 1.0 1 0 0 1 1 1 1 ML domain TLV_coat PF00429.14 EMC83875.1 - 3.9e-15 55.3 2.9 4.5e-15 55.1 1.5 1.4 1 1 1 2 2 2 1 ENV polyprotein (coat polyprotein) Mic1 PF07035.7 EMC83875.1 - 0.042 13.2 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Vac_Fusion PF02346.11 EMC83875.1 - 0.14 11.5 0.1 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein HECT PF00632.20 EMC83876.1 - 4.5e-81 272.4 0.1 6.8e-81 271.8 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.14 EMC83876.1 - 7.4e-11 42.5 0.6 5.5e-07 30.0 0.0 3.3 3 1 0 3 3 3 2 Filamin/ABP280 repeat DUF4432 PF14486.1 EMC83876.1 - 0.13 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Fcf1 PF04900.7 EMC83877.1 - 2.8e-41 139.7 1.6 5.2e-41 138.8 1.1 1.4 1 0 0 1 1 1 1 Fcf1 HPD PF05044.7 EMC83878.1 - 1.6e-82 274.8 0.1 1.8e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Homeo-prospero domain 2-oxoacid_dh PF00198.18 EMC83879.1 - 7.9e-62 208.5 0.2 9.7e-62 208.2 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMC83879.1 - 2.8e-21 74.9 0.5 4.6e-21 74.2 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMC83879.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.14 EMC83879.1 - 0.031 13.9 0.7 0.073 12.7 0.4 1.6 1 1 1 2 2 2 0 Glycine cleavage H-protein HlyD_2 PF12700.2 EMC83879.1 - 0.035 13.2 0.1 3.3 6.7 0.0 2.8 2 1 1 3 3 3 0 HlyD family secretion protein HlyD PF00529.15 EMC83879.1 - 0.044 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein PAT1 PF09770.4 EMC83879.1 - 2.4 6.2 4.4 3 5.9 3.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PDGF PF00341.12 EMC83880.1 - 1.6e-26 92.1 5.7 1.9e-26 92.0 4.0 1.0 1 0 0 1 1 1 1 PDGF/VEGF domain IF-2B PF01008.12 EMC83881.1 - 5.6e-81 271.6 0.1 6.5e-81 271.4 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family MutL_C PF08676.6 EMC83882.1 - 5.9e-13 48.6 0.3 2.9e-12 46.4 0.2 2.1 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EMC83882.1 - 1.8e-11 43.5 0.0 2.7e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EMC83882.1 - 1.4e-09 37.6 0.0 3.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC83882.1 - 1.9e-09 37.2 0.1 4.6e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acylphosphatase PF00708.13 EMC83883.1 - 4.5e-14 52.3 0.0 4.8e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase zf-C2HC_2 PF13913.1 EMC83884.1 - 1.8e-16 59.2 13.3 1.1e-08 34.4 3.2 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CHCC PF10276.4 EMC83884.1 - 0.00021 21.0 1.5 0.078 12.8 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger domain zf-H2C2_2 PF13465.1 EMC83884.1 - 0.0022 18.2 1.4 1.4 9.3 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain Nairovirus_M PF07948.6 EMC83884.1 - 0.014 13.5 0.9 0.025 12.7 0.6 1.3 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zf-RING_3 PF14369.1 EMC83884.1 - 0.056 13.4 2.3 0.32 11.0 0.1 2.3 2 0 0 2 2 2 0 zinc-finger Sgf11 PF08209.6 EMC83884.1 - 0.086 12.1 0.6 0.086 12.1 0.4 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF4574 PF15141.1 EMC83884.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) Cys_rich_CWC PF14375.1 EMC83884.1 - 0.13 12.1 4.6 3.7 7.5 0.4 2.3 2 0 0 2 2 2 0 Cysteine-rich CWC Prok-RING_4 PF14447.1 EMC83884.1 - 0.13 11.8 0.6 0.13 11.8 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_2 PF13240.1 EMC83884.1 - 0.18 11.3 3.2 7.8 6.1 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-Di19 PF05605.7 EMC83884.1 - 0.38 10.8 5.9 2.6 8.2 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EMC83884.1 - 0.78 10.2 11.2 4.6 7.7 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF329 PF03884.9 EMC83884.1 - 2.9 7.5 9.3 2.4 7.7 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-C2H2_4 PF13894.1 EMC83884.1 - 5.4 7.5 13.0 5.1 7.6 0.1 3.6 3 1 1 4 4 4 0 C2H2-type zinc finger Pkinase PF00069.20 EMC83885.1 - 3.5e-49 167.2 0.1 4.8e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.13 EMC83885.1 - 1.5e-46 156.3 24.7 1.4e-13 50.8 0.1 8.2 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC83885.1 - 1.8e-33 113.3 18.2 1.9e-07 30.5 0.2 7.6 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.12 EMC83885.1 - 2.2e-31 108.8 0.1 3.4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC83885.1 - 0.00071 18.6 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EMP24_GP25L PF01105.19 EMC83886.1 - 8.9e-38 129.8 0.1 9.9e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Flag1_repress PF03614.8 EMC83886.1 - 0.051 13.1 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin bZIP_1 PF00170.16 EMC83887.1 - 3.4e-11 42.9 9.1 4.5e-11 42.5 6.3 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC83887.1 - 1.3e-09 37.7 12.8 1.5e-09 37.5 8.9 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC83887.1 - 3.4e-07 30.4 9.5 4.5e-07 30.0 6.6 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 EMC83887.1 - 0.00046 19.4 0.2 0.00054 19.2 0.1 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M SR-25 PF10500.4 EMC83887.1 - 0.0026 17.2 9.2 0.0032 16.9 6.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HALZ PF02183.13 EMC83887.1 - 0.0064 16.1 2.6 0.0064 16.1 1.8 2.1 1 1 1 2 2 2 1 Homeobox associated leucine zipper IncA PF04156.9 EMC83887.1 - 0.0089 15.6 4.7 0.011 15.3 3.3 1.1 1 0 0 1 1 1 1 IncA protein BMP2K_C PF15282.1 EMC83887.1 - 0.028 14.5 5.1 0.029 14.5 3.6 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus MAD PF05557.8 EMC83887.1 - 0.041 11.9 7.3 0.05 11.6 5.0 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein HAP1_N PF04849.8 EMC83887.1 - 0.044 12.7 3.7 0.051 12.5 2.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AAA_11 PF13086.1 EMC83887.1 - 0.05 13.1 0.7 0.059 12.9 0.5 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 EMC83887.1 - 0.065 12.4 2.0 0.075 12.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF904 PF06005.7 EMC83887.1 - 0.068 13.4 2.2 0.068 13.4 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TBPIP PF07106.8 EMC83887.1 - 0.092 12.2 2.1 0.13 11.8 1.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EMC83887.1 - 0.11 12.5 4.9 0.14 12.1 3.4 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EMC83887.1 - 0.14 11.2 2.7 0.16 11.0 1.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 EMC83887.1 - 0.14 12.1 0.5 0.14 12.1 0.3 2.0 1 1 1 2 2 2 0 DivIVA protein CAF-1_p150 PF11600.3 EMC83887.1 - 0.34 10.2 9.3 0.4 10.0 6.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMPIT PF07851.8 EMC83887.1 - 0.44 9.5 1.6 0.55 9.2 1.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2681 PF10883.3 EMC83887.1 - 0.76 10.0 4.8 1.6 8.9 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4011 PF13195.1 EMC83887.1 - 0.78 9.7 6.3 1 9.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Mnd1 PF03962.10 EMC83887.1 - 0.96 9.0 4.8 1.2 8.7 3.4 1.1 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EMC83887.1 - 2.2 7.8 6.6 5.7 6.4 4.6 1.7 1 1 0 1 1 1 0 Septum formation initiator BORG_CEP PF14957.1 EMC83887.1 - 2.9 8.8 6.9 3.8 8.4 4.8 1.2 1 0 0 1 1 1 0 Cdc42 effector Erg28 PF03694.8 EMC83888.1 - 1.2e-09 38.1 6.1 1.6e-09 37.7 4.2 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF1129 PF06570.6 EMC83888.1 - 0.14 11.4 2.2 0.17 11.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TMEM173 PF15009.1 EMC83888.1 - 0.24 10.1 1.2 0.25 10.1 0.8 1.0 1 0 0 1 1 1 0 Transmembrane protein 173 ABC2_membrane_2 PF12679.2 EMC83888.1 - 3.6 6.3 7.5 3.8 6.3 5.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein TTL PF03133.10 EMC83889.1 - 2.7e-90 302.2 0.0 7e-90 300.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMC83889.1 - 5.8e-07 28.5 0.0 0.0016 17.2 0.0 2.7 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EMC83889.1 - 0.0033 17.1 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain XkdW PF09636.5 EMC83889.1 - 0.0051 16.6 0.5 0.7 9.7 0.2 2.9 2 0 0 2 2 2 1 XkdW protein RimK PF08443.6 EMC83889.1 - 0.025 14.0 0.0 0.064 12.7 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain GIDA PF01134.17 EMC83889.1 - 0.063 12.1 0.4 0.11 11.3 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TGF_beta PF00019.15 EMC83890.1 - 2.2e-29 101.8 1.0 4e-29 100.9 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC83890.1 - 1.3e-21 77.0 0.2 1.9e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide IFT43 PF15305.1 EMC83891.1 - 2.5e-45 154.0 3.5 3.4e-45 153.6 2.4 1.0 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Hormone_recep PF00104.25 EMC83893.1 - 7.9e-35 119.8 0.3 1.3e-34 119.1 0.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC83893.1 - 5.5e-31 106.5 12.3 1.1e-30 105.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Vasohibin PF14822.1 EMC83894.1 - 9.2e-109 362.2 0.0 1.1e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 Vasohibin LRR_6 PF13516.1 EMC83895.1 - 8e-28 93.3 23.0 0.0015 18.3 0.3 9.5 9 0 0 9 9 9 8 Leucine Rich repeat LRR_1 PF00560.28 EMC83895.1 - 2e-12 45.3 11.3 1.5 9.1 0.1 9.3 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC83895.1 - 1.2e-11 42.8 8.3 1.6 9.2 0.0 8.7 8 0 0 8 8 8 2 Leucine rich repeat LRR_4 PF12799.2 EMC83895.1 - 2.9e-09 36.3 22.4 0.0014 18.1 0.1 5.3 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) EF-hand_1 PF00036.27 EMC83895.1 - 4.9e-06 25.4 0.1 0.011 14.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC83895.1 - 5.2e-06 25.9 0.1 0.005 16.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EMC83895.1 - 0.00041 20.4 0.1 0.0017 18.4 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair LRR_8 PF13855.1 EMC83895.1 - 0.0036 17.0 28.1 0.058 13.1 3.5 5.5 3 2 3 6 6 6 2 Leucine rich repeat LRR_2 PF07723.8 EMC83895.1 - 0.047 14.2 0.2 80 3.9 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat zf-DHHC PF01529.15 EMC83897.1 - 1.6e-17 63.4 10.2 1.6e-17 63.4 7.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase InaF-motif PF15018.1 EMC83897.1 - 0.36 10.3 4.1 0.8 9.2 2.8 1.6 1 0 0 1 1 1 0 TRP-interacting helix CoA_binding_3 PF13727.1 EMC83897.1 - 1.1 9.0 6.9 0.085 12.6 1.5 1.6 2 0 0 2 2 2 0 CoA-binding domain DUF221 PF02714.10 EMC83898.1 - 1.3e-90 303.5 26.2 1.3e-90 303.5 18.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC83898.1 - 4.8e-25 87.9 1.8 4.8e-25 87.9 1.2 5.3 5 2 0 5 5 5 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMC83898.1 - 1.1e-11 45.0 0.2 2.2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Globin PF00042.17 EMC83899.1 - 4.2e-10 39.9 0.0 1.2e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 Globin PMT PF02366.13 EMC83900.1 - 7.6e-76 254.6 14.2 1.7e-75 253.5 9.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMC83900.1 - 1e-25 90.3 0.4 1.5e-25 89.8 0.3 1.2 1 0 0 1 1 1 1 MIR domain GST_N_3 PF13417.1 EMC83901.1 - 1.1e-18 67.1 0.0 1.8e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC83901.1 - 1.4e-16 60.2 0.0 2.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC83901.1 - 1.6e-15 57.0 0.0 3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC83901.1 - 1.8e-07 31.0 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC83901.1 - 6.2e-05 22.8 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC83901.1 - 0.0067 16.8 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EMC83901.1 - 0.028 14.3 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GOLD_2 PF13897.1 EMC83902.1 - 2.1e-31 108.9 1.5 3e-31 108.4 1.1 1.2 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Golgin_A5 PF09787.4 EMC83905.1 - 6.5e-144 480.2 0.2 8.4e-144 479.8 0.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 Vps16_C PF04840.7 EMC83905.1 - 3e-11 42.8 3.7 2.1e-10 40.0 2.6 2.0 1 1 0 1 1 1 1 Vps16, C-terminal region DUF3105 PF11303.3 EMC83905.1 - 0.11 12.3 0.0 3.2 7.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3105) AMOP PF03782.12 EMC83906.1 - 1.6e-42 145.0 2.2 1.6e-42 145.0 1.5 1.9 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.14 EMC83906.1 - 2.2e-07 30.8 12.2 2.2e-07 30.8 8.5 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain Daxx PF03344.10 EMC83906.1 - 0.1 11.0 10.7 0.14 10.6 7.4 1.2 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 EMC83906.1 - 1.8 7.6 11.6 2.7 7.0 8.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 EMC83906.1 - 2.6 6.6 15.8 4.5 5.8 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 EMC83906.1 - 4.7 5.3 9.6 7.4 4.6 6.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Aminotran_1_2 PF00155.16 EMC83907.1 - 7.8e-61 206.0 0.0 9.4e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMC83907.1 - 0.0023 17.1 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMC83907.1 - 0.0061 15.3 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V 2OG-FeII_Oxy_2 PF13532.1 EMC83908.1 - 1.1e-39 136.2 0.0 3.1e-39 134.8 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SKIP_SNW PF02731.10 EMC83909.1 - 3e-66 221.7 7.9 3e-66 221.7 5.5 2.5 2 0 0 2 2 2 1 SKIP/SNW domain ABC1 PF03109.11 EMC83910.1 - 8.8e-40 135.3 0.1 1.5e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EMC83910.1 - 0.00047 19.9 0.9 0.12 12.0 0.1 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 EMC83910.1 - 0.00082 18.5 0.0 0.0031 16.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Laminin_G_2 PF02210.19 EMC83911.1 - 1.3e-22 80.1 0.0 2.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EMC83911.1 - 1.6e-17 63.7 0.0 2.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 EMC83911.1 - 1.9e-06 27.7 6.8 3.9e-06 26.6 4.7 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_G_3 PF13385.1 EMC83911.1 - 0.018 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EMC83912.1 - 1.1e-109 361.7 6.5 5.8e-31 107.1 0.0 4.1 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.18 EMC83912.1 - 1.9e-84 280.2 1.5 1.4e-25 89.8 0.0 4.4 4 1 0 4 4 4 4 Laminin G domain Laminin_G_3 PF13385.1 EMC83912.1 - 6.4e-21 75.2 4.0 1.3e-05 25.4 0.3 4.3 4 0 0 4 4 4 4 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.6 EMC83912.1 - 2.6e-07 30.7 0.3 0.97 9.2 0.0 4.4 4 0 0 4 4 4 3 Domain of Unknown Function (DUF1080) EGF PF00008.22 EMC83912.1 - 1.4e-06 28.1 19.3 0.0044 16.9 4.1 2.6 2 0 0 2 2 2 2 EGF-like domain Laminin_G_2 PF02210.19 EMC83913.1 - 6.8e-16 58.4 0.1 1.1e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EMC83913.1 - 1.1e-05 25.4 0.2 1.8e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 EMC83913.1 - 0.031 14.5 0.2 0.055 13.6 0.1 1.4 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF3439 PF11921.3 EMC83913.1 - 0.24 11.1 5.3 0.39 10.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Syndecan PF01034.15 EMC83914.1 - 1.6e-06 27.6 3.0 6.2e-06 25.7 2.1 2.0 1 1 0 1 1 1 1 Syndecan domain CD34_antigen PF06365.7 EMC83914.1 - 0.0069 16.0 0.1 0.0097 15.5 0.1 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF202 PF02656.10 EMC83914.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) 7tm_1 PF00001.16 EMC83915.1 - 7.1e-35 120.3 22.8 1.1e-34 119.7 15.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.1 EMC83915.1 - 1.6e-15 56.6 4.5 3.2e-06 26.8 0.2 4.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_5 PF13306.1 EMC83915.1 - 2.5e-11 43.3 1.6 1.9e-06 27.6 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 EMC83915.1 - 2.9e-06 26.7 5.1 1.6 8.4 0.3 5.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) GnHR_trans PF12369.3 EMC83915.1 - 0.027 14.9 1.1 0.027 14.9 0.8 2.9 3 0 0 3 3 3 0 Gonadotropin hormone receptor transmembrane region TFIIA PF03153.8 EMC83916.1 - 5.2e-91 306.3 50.9 3e-88 297.2 35.3 2.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.8 EMC83916.1 - 0.56 10.6 11.9 0.86 10.0 0.8 2.4 2 0 0 2 2 2 0 Senescence regulator Pox_Ag35 PF03286.9 EMC83916.1 - 1.4 8.3 12.3 0.62 9.5 4.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RXT2_N PF08595.6 EMC83916.1 - 5.5 6.7 10.7 1 9.1 2.8 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Zip PF02535.17 EMC83916.1 - 7.8 5.4 7.8 0.94 8.4 1.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Stonin2_N PF12016.3 EMC83917.1 - 6.1e-109 364.2 33.8 8.6e-109 363.7 23.5 1.2 1 0 0 1 1 1 1 Stonin 2 Adap_comp_sub PF00928.16 EMC83917.1 - 2.4e-52 177.6 1.1 2.7e-52 177.4 0.1 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Sel1 PF08238.7 EMC83918.1 - 6e-68 223.8 38.3 5.2e-09 36.4 0.2 12.9 12 0 0 12 12 12 11 Sel1 repeat fn2 PF00040.14 EMC83918.1 - 4.5e-19 68.1 5.8 8.6e-19 67.2 4.0 1.5 1 0 0 1 1 1 1 Fibronectin type II domain MACPF PF01823.14 EMC83921.1 - 8e-24 84.5 0.0 1.3e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain zf-RING_2 PF13639.1 EMC83922.1 - 3e-09 36.5 2.4 6.9e-09 35.4 1.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC83922.1 - 4.6e-08 33.0 1.0 8.9e-08 32.1 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC83922.1 - 1.4e-07 31.0 1.6 2.7e-07 30.1 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC83922.1 - 8.7e-06 25.3 1.7 2e-05 24.2 1.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC83922.1 - 7.3e-05 22.5 1.5 0.00017 21.3 1.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMC83922.1 - 0.00017 21.5 3.4 0.0042 17.0 0.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC83922.1 - 0.0009 18.8 2.1 0.0031 17.1 1.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC83922.1 - 0.0013 18.6 3.5 0.0055 16.5 0.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC83922.1 - 0.0069 16.0 1.5 0.0069 16.0 1.1 2.3 2 1 0 2 2 2 1 RING-type zinc-finger PHD PF00628.24 EMC83922.1 - 0.022 14.4 1.8 0.033 13.8 0.2 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.1 EMC83922.1 - 0.031 13.8 1.1 0.06 12.9 0.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EMC83922.1 - 0.034 14.1 2.1 0.12 12.3 1.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Trm112p PF03966.11 EMC83922.1 - 0.038 14.3 0.1 0.073 13.4 0.1 1.5 1 0 0 1 1 1 0 Trm112p-like protein zf-UDP PF14569.1 EMC83922.1 - 0.047 13.4 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Nse PF11789.3 EMC83922.1 - 0.096 12.2 1.5 0.19 11.2 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.1 EMC83922.1 - 0.099 12.2 0.6 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 EMC83922.1 - 0.2 11.4 3.0 5.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-LITAF-like PF10601.4 EMC83922.1 - 1.2 9.0 4.3 3 7.7 3.0 1.8 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain IRK PF01007.15 EMC83924.1 - 1.6e-166 553.1 0.9 2e-166 552.8 0.6 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC83924.1 - 0.0025 17.4 8.7 0.0071 16.0 6.0 1.8 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 EMC83924.1 - 0.2 10.9 5.7 0.3 10.3 4.0 1.2 1 0 0 1 1 1 0 Ion transport protein IRK PF01007.15 EMC83925.1 - 3.7e-151 502.6 0.6 4.5e-151 502.3 0.4 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC83925.1 - 1.3 8.7 8.3 5.7 6.7 5.9 2.0 1 1 1 2 2 2 0 Ion channel Ets PF00178.17 EMC83926.1 - 1.2e-39 134.3 0.7 1.2e-39 134.3 0.5 1.7 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 EMC83926.1 - 1.1e-26 92.3 0.1 2.3e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain I-set PF07679.11 EMC83927.1 - 1.7e-42 143.1 0.1 7.4e-12 44.9 0.0 5.7 5 2 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC83927.1 - 4.2e-38 129.3 0.0 7.5e-09 35.6 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 EMC83927.1 - 1.1e-26 93.0 1.7 1e-05 25.9 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 EMC83927.1 - 8.3e-19 67.4 0.2 4.1e-06 26.8 0.0 6.3 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 EMC83927.1 - 4.3e-15 55.5 1.4 0.022 14.6 0.0 6.7 4 4 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC83927.1 - 1.7e-13 50.2 0.1 4.2e-08 32.9 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC83927.1 - 4.5e-06 26.5 0.1 0.0058 16.5 0.0 4.8 5 1 0 5 5 5 1 Immunoglobulin C1-set domain Marek_A PF02124.10 EMC83927.1 - 0.017 14.5 1.0 0.12 11.8 0.1 2.3 2 0 0 2 2 2 0 Marek's disease glycoprotein A Mid2 PF04478.7 EMC83927.1 - 0.019 14.3 0.3 0.042 13.2 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Glyco_transf_29 PF00777.13 EMC83928.1 - 1.4e-74 250.6 0.0 1.6e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DcpS_C PF11969.3 EMC83929.1 - 1.5e-30 105.8 0.1 3.7e-30 104.5 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EMC83929.1 - 4.8e-19 68.7 0.1 8.1e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal TIR_2 PF13676.1 EMC83930.1 - 3.5e-13 49.5 0.0 5.1e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.15 EMC83930.1 - 5.5e-12 45.3 0.0 7.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 TIR domain SIR2_2 PF13289.1 EMC83931.1 - 7.7e-19 67.9 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 SIR2-like domain RFC1 PF08519.7 EMC83931.1 - 0.07 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain SRP-alpha_N PF04086.8 EMC83932.1 - 8.8e-65 218.8 9.6 1.2e-64 218.4 6.6 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EMC83932.1 - 1e-34 119.7 0.5 2.1e-30 105.6 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EMC83932.1 - 4.9e-08 32.9 0.9 1.8e-07 31.1 0.0 2.4 2 1 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EMC83932.1 - 0.00085 18.1 0.2 0.0025 16.6 0.1 1.7 1 1 0 1 1 1 1 ArgK protein CbiA PF01656.18 EMC83932.1 - 0.0011 18.4 0.5 0.0042 16.5 0.3 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ETF PF01012.16 EMC83932.1 - 0.061 13.0 1.7 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain PSK_trans_fac PF07704.6 EMC83932.1 - 0.086 13.5 0.3 0.98 10.1 0.0 2.8 2 0 0 2 2 2 0 Rv0623-like transcription factor AAA_33 PF13671.1 EMC83932.1 - 0.13 12.1 0.4 1.5 8.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMC83932.1 - 0.16 12.0 0.5 1.3 9.2 0.0 2.7 3 1 0 3 3 3 0 AAA domain GNT-I PF03071.10 EMC83933.1 - 5.8e-151 502.8 0.0 2e-141 471.4 0.4 2.0 1 1 1 2 2 2 2 GNT-I family DnaJ PF00226.26 EMC83935.1 - 1.7e-29 101.3 4.5 2.4e-29 100.8 3.1 1.2 1 0 0 1 1 1 1 DnaJ domain Catalase-rel PF06628.7 EMC83935.1 - 0.028 14.2 0.1 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 Catalase-related immune-responsive Y_phosphatase PF00102.22 EMC83936.1 - 1.3e-78 263.5 0.1 1.9e-78 263.0 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC83936.1 - 0.0004 19.9 0.0 0.00091 18.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Condensin2nSMC PF12422.3 EMC83937.1 - 1.2e-66 223.1 6.8 9.2e-51 171.5 0.6 4.2 5 0 0 5 5 5 2 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 EMC83937.1 - 2e-06 27.3 0.3 4.2 7.6 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EMC83937.1 - 0.00011 22.4 0.0 0.13 12.6 0.0 3.2 1 1 2 3 3 3 3 HEAT repeats Vac14_Fab1_bd PF12755.2 EMC83937.1 - 0.013 15.9 0.1 0.17 12.2 0.0 3.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF577 PF04510.7 EMC83937.1 - 0.044 13.4 7.9 1.7 8.3 0.0 4.7 5 1 0 5 5 5 0 Family of unknown function (DUF577) PPR PF01535.15 EMC83937.1 - 0.088 12.8 0.1 0.5 10.4 0.0 2.3 1 0 0 1 1 1 0 PPR repeat Lipase_GDSL_2 PF13472.1 EMC83938.1 - 0.008 16.3 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pyr_redox_2 PF07992.9 EMC83939.1 - 1e-16 61.4 0.0 2.1e-16 60.4 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC83939.1 - 0.0065 16.5 0.0 0.076 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Helicase_C PF00271.26 EMC83940.1 - 2.9e-18 65.4 0.0 1.7e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC83940.1 - 5.1e-18 65.1 0.1 1.8e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 EMC83940.1 - 0.00091 18.9 0.0 0.0043 16.7 0.0 2.2 2 1 0 2 2 2 1 RQC domain ResIII PF04851.10 EMC83940.1 - 0.0019 18.0 0.0 0.01 15.6 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Got1 PF04178.7 EMC83941.1 - 8e-22 77.5 14.7 9e-22 77.4 10.2 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 EMC83941.1 - 0.015 15.2 11.5 0.015 15.2 7.9 2.4 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Fzo_mitofusin PF04799.8 EMC83941.1 - 0.043 13.1 0.4 0.06 12.7 0.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region Aminotran_4 PF01063.14 EMC83942.1 - 5.5e-24 84.9 0.0 7.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Macoilin PF09726.4 EMC83943.1 - 0.013 13.8 1.6 0.013 13.8 1.1 1.1 1 0 0 1 1 1 0 Transmembrane protein SPC12 PF06645.8 EMC83944.1 - 1.7e-34 117.4 0.4 2e-34 117.1 0.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 EMC83944.1 - 0.0042 15.8 0.0 0.0046 15.7 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MerC PF03203.9 EMC83944.1 - 0.05 13.9 0.1 0.054 13.8 0.1 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein MFS_2 PF13347.1 EMC83944.1 - 0.072 11.4 0.8 0.092 11.1 0.5 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein SdpI PF13630.1 EMC83944.1 - 0.074 12.7 1.8 0.098 12.3 1.2 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF443 PF04276.7 EMC83944.1 - 0.091 12.1 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) FUN14 PF04930.10 EMC83944.1 - 1 9.6 3.6 1.5 9.1 2.5 1.2 1 0 0 1 1 1 0 FUN14 family Glyco_transf_8 PF01501.15 EMC83945.1 - 2.6e-47 161.2 0.1 3.1e-47 161.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_3 PF13641.1 EMC83945.1 - 0.071 12.8 0.5 13 5.4 0.1 2.7 2 1 0 3 3 3 0 Glycosyltransferase like family 2 GN3L_Grn1 PF08701.6 EMC83946.1 - 5.8e-20 70.9 29.0 5.8e-20 70.9 20.1 3.6 2 1 1 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EMC83946.1 - 5.4e-15 55.3 0.2 3.3e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC83946.1 - 4.3e-07 29.3 0.0 3.5e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMC83946.1 - 0.0075 16.0 0.0 0.0075 16.0 0.0 3.7 3 1 0 3 3 3 1 Dynamin family Miro PF08477.8 EMC83946.1 - 0.039 14.4 0.8 0.57 10.6 0.0 3.0 2 1 0 2 2 2 0 Miro-like protein ArgK PF03308.11 EMC83946.1 - 0.062 12.0 0.1 0.062 12.0 0.1 2.1 2 1 0 2 2 2 0 ArgK protein UPF0640 PF15114.1 EMC83947.1 - 7.2e-37 124.6 4.1 7.9e-37 124.5 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 EF-hand_8 PF13833.1 EMC83948.1 - 2e-29 100.9 17.9 7.6e-15 54.2 0.2 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EMC83948.1 - 5.2e-27 91.0 24.0 1.1e-08 33.7 0.7 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 EMC83948.1 - 1.9e-26 91.9 9.6 3.8e-16 58.9 4.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC83948.1 - 8.9e-22 74.9 14.7 2e-07 30.2 1.3 5.1 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC83948.1 - 2.7e-13 48.5 24.0 1.3e-06 27.4 0.2 4.9 5 1 1 6 6 6 3 EF hand EF-hand_9 PF14658.1 EMC83948.1 - 4.4e-12 45.7 0.6 6.3e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC83948.1 - 1.4e-06 27.9 6.9 0.0098 15.6 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC83948.1 - 0.00014 21.8 1.0 0.0051 16.8 0.5 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EMC83948.1 - 0.00097 18.8 0.3 0.098 12.3 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB UPF0154 PF03672.8 EMC83948.1 - 0.026 14.1 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF1707 PF08044.6 EMC83948.1 - 0.033 13.9 0.7 0.85 9.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_10 PF14788.1 EMC83948.1 - 0.073 12.7 0.7 0.073 12.7 0.5 3.0 3 1 1 4 4 3 0 EF hand vATP-synt_AC39 PF01992.11 EMC83948.1 - 0.076 12.1 0.6 0.099 11.7 0.4 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit TBPIP PF07106.8 EMC83948.1 - 0.081 12.4 0.1 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF21 PF01595.15 EMC83948.1 - 0.11 11.7 0.1 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF1456 PF07308.8 EMC83948.1 - 0.15 12.0 2.2 6 6.9 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1456) HalX PF08663.5 EMC83948.1 - 0.32 11.0 1.9 2.3 8.2 0.1 2.6 3 0 0 3 3 2 0 HalX domain RNA_pol_Rpb4 PF03874.11 EMC83948.1 - 0.49 10.4 3.5 13 5.8 0.1 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb4 Ribosomal_L29e PF01779.12 EMC83949.1 - 1.5e-16 59.9 0.9 1.5e-16 59.9 0.6 2.2 2 0 0 2 2 2 2 Ribosomal L29e protein family HSF_DNA-bind PF00447.12 EMC83950.1 - 1.3e-20 73.4 0.2 1.5e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding DSPc PF00782.15 EMC83951.1 - 5.5e-43 145.7 0.0 7.8e-43 145.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EMC83951.1 - 2e-05 24.8 0.0 6.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 EMC83951.1 - 9.7e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC83951.1 - 0.0024 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.27 EMC83952.1 - 1.9e-82 268.4 19.9 1.2e-12 47.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC83952.1 - 5.2e-10 39.3 0.4 6.8e-06 25.9 0.0 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMC83952.1 - 0.0008 17.7 0.1 2.4 6.3 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EMC83952.1 - 0.00081 18.6 0.5 0.37 10.1 0.0 3.1 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature TLD PF07534.11 EMC83952.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 TLD AF-4 PF05110.8 EMC83953.1 - 1.3 6.8 6.9 1.6 6.4 4.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Aminotran_1_2 PF00155.16 EMC83954.1 - 8.3e-71 238.8 0.0 1.4e-70 238.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.5 EMC83954.1 - 4.6e-10 39.4 0.2 9.6e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.15 EMC83954.1 - 2.2e-07 29.5 0.0 1e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMC83954.1 - 1.5e-06 27.1 0.0 2.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC83954.1 - 0.00053 19.2 0.0 0.00091 18.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMC83954.1 - 0.003 16.6 0.5 0.012 14.7 0.4 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.27 EMC83955.1 - 2.5e-29 100.0 3.0 8.3e-08 31.8 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Cofilin_ADF PF00241.15 EMC83955.1 - 1.5e-25 89.5 0.3 1.1e-12 47.9 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Nup160 PF11715.3 EMC83955.1 - 0.0071 14.5 0.0 2 6.4 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PP2C PF00481.16 EMC83956.1 - 2.7e-34 118.7 0.0 1.5e-15 57.2 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EMC83956.1 - 8.5e-06 25.6 0.1 0.025 14.2 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EMC83956.1 - 5.9e-05 22.5 0.1 0.001 18.4 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C DUF4147 PF13660.1 EMC83957.1 - 4.2e-73 245.3 1.0 6.2e-73 244.8 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 EMC83957.1 - 9e-36 122.2 0.4 1.7e-35 121.3 0.2 1.5 1 0 0 1 1 1 1 MOFRL family Peptidase_C12 PF01088.16 EMC83959.1 - 2.8e-56 190.1 0.0 5.6e-56 189.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Nucleo_P87 PF07267.6 EMC83959.1 - 0.13 10.9 8.7 0.2 10.3 6.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_6 PF12697.2 EMC83960.1 - 2e-18 67.1 2.3 5.8e-10 39.4 0.1 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC83960.1 - 2.4e-11 43.6 0.0 2.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC83960.1 - 7.6e-10 38.7 0.0 5.3e-06 26.1 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EMC83960.1 - 0.00084 18.6 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EMC83960.1 - 0.044 13.6 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.2 EMC83961.1 - 8.8e-21 74.8 1.4 4e-11 43.2 0.2 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC83961.1 - 1.7e-13 50.5 0.0 2.1e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC83961.1 - 1.1e-07 31.6 0.1 0.00057 19.5 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EMC83961.1 - 0.0011 18.3 0.1 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EMC83961.1 - 0.029 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 EMC83961.1 - 0.037 13.4 0.0 0.92 8.8 0.0 2.4 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 EMC83961.1 - 0.082 12.3 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) KH_1 PF00013.24 EMC83962.1 - 3e-48 161.2 13.3 1.1e-17 63.4 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMC83962.1 - 1.7e-34 116.8 19.8 1.9e-11 43.3 2.8 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMC83962.1 - 2.5e-14 52.5 4.0 0.00027 20.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMC83962.1 - 2.7e-07 30.1 1.0 0.015 14.9 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EMC83962.1 - 0.0031 17.2 4.4 7.2 6.4 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain 7tm_1 PF00001.16 EMC83963.1 - 6e-41 140.2 22.8 8.3e-41 139.8 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PARP PF00644.15 EMC83964.1 - 3.8e-24 85.2 0.0 5.5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Sema PF01403.14 EMC83965.1 - 9.3e-170 564.8 0.0 1.1e-169 564.5 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 EMC83965.1 - 0.00027 21.0 9.4 0.00027 21.0 6.5 2.0 2 0 0 2 2 2 1 Plexin repeat G-alpha PF00503.15 EMC83966.1 - 4.6e-128 427.2 1.0 5.5e-128 426.9 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC83966.1 - 2e-14 53.2 2.6 8.9e-11 41.3 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC83966.1 - 0.00054 19.1 0.6 0.64 9.1 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF2951 PF11166.3 EMC83966.1 - 0.017 14.9 0.3 0.049 13.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Miro PF08477.8 EMC83966.1 - 0.017 15.6 0.5 0.92 10.0 0.1 2.9 2 1 1 3 3 3 0 Miro-like protein AAA_29 PF13555.1 EMC83966.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EMC83967.1 - 1.7e-127 425.3 3.3 2e-127 425.1 2.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC83967.1 - 6.3e-14 51.5 0.1 7.7e-13 48.0 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EMC83967.1 - 0.032 14.7 0.8 5.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein Sema PF01403.14 EMC83968.1 - 2.8e-160 533.5 0.0 4.6e-160 532.8 0.0 1.3 1 1 0 1 1 1 1 Sema domain PSI PF01437.20 EMC83968.1 - 0.00022 21.2 7.2 0.00022 21.2 5.0 1.9 2 0 0 2 2 2 1 Plexin repeat OAS1_C PF10421.4 EMC83969.1 - 4.7e-61 205.6 0.0 8.7e-61 204.7 0.0 1.4 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ubiquitin PF00240.18 EMC83969.1 - 1.4e-28 98.0 0.3 4.6e-20 70.7 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EMC83969.1 - 1.4e-12 47.1 0.1 3.2e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC83969.1 - 4.4e-11 42.8 0.5 1.2e-05 25.4 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-like domain NTP_transf_2 PF01909.18 EMC83969.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain UN_NPL4 PF11543.3 EMC83969.1 - 0.0086 16.3 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 IFRD PF05004.8 EMC83970.1 - 9.2e-85 284.4 0.5 1.1e-84 284.1 0.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 EMC83970.1 - 4.4e-25 87.6 2.1 6.2e-25 87.1 0.4 2.1 2 0 0 2 2 2 1 Interferon-related protein conserved region WD40 PF00400.27 EMC83971.1 - 1.5e-27 94.4 11.4 9.6e-09 34.8 0.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat HPS3_N PF14761.1 EMC83971.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 ANF_receptor PF01094.23 EMC83972.1 - 6.6e-91 304.6 0.1 8.1e-91 304.3 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 EMC83972.1 - 1.1e-73 247.5 15.4 1.9e-73 246.7 10.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 EMC83972.1 - 5.8e-15 54.7 8.8 5.8e-15 54.7 6.1 2.2 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 EMC83972.1 - 1.2e-09 38.0 0.3 7.1e-09 35.4 0.4 1.8 2 0 0 2 2 2 1 Periplasmic binding protein FDC-SP PF15215.1 EMC83972.1 - 0.058 13.7 0.7 0.16 12.2 0.5 1.7 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide IQ PF00612.22 EMC83973.1 - 1e-08 34.0 3.8 6.2e-07 28.4 0.3 5.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif Ras PF00071.17 EMC83974.1 - 1.7e-57 193.3 0.0 2e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC83974.1 - 8.5e-17 61.7 0.0 1.4e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC83974.1 - 8.6e-10 38.1 0.0 1.6e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC83974.1 - 0.00013 21.4 0.0 0.00035 20.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC83974.1 - 0.012 14.7 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMC83974.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GSHPx PF00255.14 EMC83975.1 - 1.5e-09 37.1 0.1 2.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase DUF106 PF01956.11 EMC83976.1 - 2.5e-36 124.7 4.6 4.6e-36 123.8 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF106 FancD2 PF14631.1 EMC83977.1 - 0 2414.8 25.5 0 2414.5 17.7 1.1 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease Peptidase_S9 PF00326.16 EMC83978.1 - 1.2e-24 86.6 0.0 1.7e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMC83978.1 - 6.4e-13 49.1 5.5 6.4e-13 49.1 3.8 2.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC83978.1 - 7.5e-13 48.4 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMC83978.1 - 2.1e-05 23.9 0.0 3.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMC83978.1 - 7.5e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMC83978.1 - 0.00027 20.5 0.2 0.00078 19.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMC83978.1 - 0.0073 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 EMC83978.1 - 0.027 14.1 0.0 0.06 13.0 0.0 1.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EMC83978.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Kringle PF00051.13 EMC83979.1 - 7.3e-90 295.1 38.5 1e-28 99.1 2.3 4.4 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.21 EMC83979.1 - 7.9e-22 77.9 0.0 1.5e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 EMC83979.1 - 1.5e-10 40.6 0.1 4.6e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EMC83979.1 - 0.00023 20.7 2.6 0.0016 18.0 0.2 3.2 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.6 EMC83979.1 - 0.051 13.4 0.1 0.051 13.4 0.0 2.8 2 0 0 2 2 2 0 PAN-like domain ThiF PF00899.16 EMC83981.1 - 2.3e-44 150.5 0.0 5.6e-34 116.8 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EMC83981.1 - 1.1e-34 117.8 0.8 1.2e-25 88.8 0.1 3.1 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMC83981.1 - 1.5e-16 59.5 0.2 2.5e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site UBA_e1_C PF09358.5 EMC83981.1 - 6.9e-07 29.4 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain MoeZ_MoeB PF05237.8 EMC83981.1 - 0.0032 17.0 0.0 0.0087 15.6 0.0 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain IPK PF03770.11 EMC83982.1 - 1.1e-63 214.5 0.0 1.6e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase NTP_transferase PF00483.18 EMC83983.1 - 1.1e-19 70.6 0.0 2.5e-19 69.5 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EMC83983.1 - 5.8e-13 47.7 17.4 1.5e-07 30.6 3.6 3.8 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMC83983.1 - 1.5e-05 24.4 2.8 1.5e-05 24.4 1.9 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase SPRY PF00622.23 EMC83984.1 - 1.7e-25 89.5 0.2 3.3e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 EMC83984.1 - 5.4e-07 29.1 9.8 5.4e-07 29.1 6.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC83984.1 - 4.5e-05 23.3 13.4 0.00013 21.8 9.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC83984.1 - 0.013 15.1 14.0 0.036 13.7 9.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC83984.1 - 0.021 14.5 12.2 0.054 13.2 8.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EMC83984.1 - 0.056 13.2 10.7 0.18 11.6 7.4 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EMC83984.1 - 8.7 6.3 10.8 24 4.9 7.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LRR_8 PF13855.1 EMC83985.1 - 4.4e-27 93.6 11.8 2e-14 53.0 1.0 3.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC83985.1 - 6e-18 64.0 12.3 4.7e-07 29.2 0.1 4.7 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC83985.1 - 1.8e-17 60.6 10.4 0.0049 16.7 0.1 8.4 9 0 0 9 9 9 6 Leucine Rich Repeat LRR_6 PF13516.1 EMC83985.1 - 2.4e-12 45.5 1.1 0.077 13.0 0.0 6.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 EMC83985.1 - 3.6e-09 35.3 19.5 0.19 12.0 0.1 8.2 8 0 0 8 8 8 5 Leucine rich repeat LRR_5 PF13306.1 EMC83985.1 - 4.7e-07 29.5 0.0 1.3e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC83985.1 - 0.0026 17.3 0.1 0.035 13.6 0.0 2.1 1 1 1 2 2 2 1 Leucine-rich repeat Racemase_4 PF13615.1 EMC83985.1 - 0.017 15.3 0.4 0.051 13.8 0.3 1.8 1 0 0 1 1 1 0 Putative alanine racemase zf-HC5HC2H PF13771.1 EMC83986.1 - 1.4e-16 60.3 3.0 1.4e-16 60.3 2.0 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC83986.1 - 1.5e-08 34.5 3.9 1.5e-08 34.5 2.7 2.9 1 1 1 2 2 2 1 PHD-zinc-finger like domain zf-RING_2 PF13639.1 EMC83986.1 - 3.1e-05 23.6 9.1 3.1e-05 23.6 6.3 4.0 4 1 0 4 4 4 1 Ring finger domain Trm112p PF03966.11 EMC83986.1 - 0.23 11.8 1.8 0.62 10.4 0.2 2.3 2 0 0 2 2 2 0 Trm112p-like protein PhnA_Zn_Ribbon PF08274.7 EMC83986.1 - 0.72 9.6 13.9 4.1 7.2 0.3 5.4 5 2 1 6 6 6 0 PhnA Zinc-Ribbon zf-rbx1 PF12678.2 EMC83986.1 - 3.3 7.8 23.7 0.14 12.2 4.4 3.3 2 1 1 3 3 3 0 RING-H2 zinc finger Shisa PF13908.1 EMC83987.1 - 7.3e-09 36.0 15.3 7.3e-09 36.0 10.6 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator BTG PF07742.7 EMC83988.1 - 1.5e-30 105.1 0.0 1.8e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 BTG family Ins_P5_2-kin PF06090.7 EMC83989.1 - 7.4e-95 317.5 1.1 8.6e-95 317.3 0.8 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase LRR_8 PF13855.1 EMC83990.1 - 4.8e-48 160.7 22.8 1.3e-15 56.8 0.0 6.6 5 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EMC83990.1 - 5.6e-37 124.7 30.1 1.3e-06 27.9 0.4 9.2 3 1 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC83990.1 - 1.6e-27 91.3 25.9 0.16 12.0 0.0 14.1 14 1 1 15 15 14 8 Leucine Rich Repeat LRR_6 PF13516.1 EMC83990.1 - 9.2e-17 59.2 25.8 0.028 14.4 0.0 11.9 12 1 1 13 13 12 5 Leucine Rich repeat LRR_7 PF13504.1 EMC83990.1 - 2.5e-12 44.8 24.6 1.6 9.2 0.1 12.3 14 0 0 14 14 12 3 Leucine rich repeat VWC PF00093.13 EMC83990.1 - 2.7e-11 43.3 13.4 6.8e-11 42.1 9.3 1.7 1 0 0 1 1 1 1 von Willebrand factor type C domain LRR_5 PF13306.1 EMC83990.1 - 1.5e-09 37.6 0.3 0.00021 20.9 0.0 3.3 2 1 3 5 5 5 3 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC83990.1 - 7.3e-06 25.6 4.3 0.014 14.9 0.2 4.8 1 1 4 5 5 5 2 Leucine-rich repeat DUF2011 PF09428.5 EMC83990.1 - 0.00083 19.2 3.3 0.0017 18.2 2.3 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) LRRNT PF01462.13 EMC83990.1 - 0.00096 18.5 5.2 0.018 14.5 0.0 3.8 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain FNIP PF05725.7 EMC83990.1 - 0.14 12.1 12.2 6.1 6.8 0.2 4.7 4 1 0 4 4 4 0 FNIP Repeat Amnionless PF14828.1 EMC83990.1 - 1.3 7.4 12.7 2 6.8 8.8 1.2 1 0 0 1 1 1 0 Amnionless LRR_8 PF13855.1 EMC83991.1 - 2.4e-69 228.9 41.1 6.4e-13 48.2 0.3 9.4 5 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 EMC83991.1 - 2.4e-47 157.8 55.8 2.8e-06 26.8 0.1 12.5 5 4 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC83991.1 - 8e-30 98.2 42.7 0.0042 16.9 0.1 19.5 17 3 4 21 21 21 8 Leucine Rich Repeat LRR_5 PF13306.1 EMC83991.1 - 8.4e-19 67.5 5.9 7.2e-07 28.9 0.0 5.3 2 2 2 5 5 5 5 Leucine rich repeats (6 copies) LRRNT PF01462.13 EMC83991.1 - 3.2e-12 45.5 21.5 4.6e-07 29.1 1.1 6.3 6 0 0 6 6 6 2 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EMC83991.1 - 1.4e-11 42.5 41.8 0.041 14.0 0.1 16.6 19 1 1 20 20 20 2 Leucine rich repeat LRR_6 PF13516.1 EMC83991.1 - 1.9e-10 39.6 51.7 6.9 7.0 0.0 16.6 17 2 1 18 18 18 2 Leucine Rich repeat LRR_9 PF14580.1 EMC83991.1 - 3e-10 39.9 9.6 0.0071 15.9 0.1 5.0 3 3 1 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.1 EMC83992.1 - 1.4e-21 75.9 3.0 4.5e-09 35.9 0.0 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC83992.1 - 1.3e-16 59.8 5.0 2.5e-05 23.8 0.2 4.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC83992.1 - 3.9e-14 50.5 2.0 0.033 14.1 0.0 6.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 EMC83992.1 - 1.1e-06 28.1 0.5 5.9 7.2 0.1 5.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 EMC83992.1 - 3.5e-06 26.3 3.1 2.9 8.4 0.0 5.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_5 PF13306.1 EMC83992.1 - 1.6e-05 24.6 0.4 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) CENP-P PF13096.1 EMC83993.1 - 5.8e-32 110.4 0.9 5.8e-32 110.4 0.6 1.7 2 0 0 2 2 2 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Cep57_CLD_2 PF14197.1 EMC83993.1 - 0.24 11.3 6.6 2.7 7.9 0.8 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Kinesin-relat_1 PF12711.2 EMC83993.1 - 0.94 9.9 5.9 0.52 10.7 2.3 2.0 2 1 0 2 2 2 0 Kinesin motor SlyX PF04102.7 EMC83993.1 - 1.2 9.5 4.3 0.95 9.8 0.2 2.4 3 0 0 3 3 3 0 SlyX tRNA-synt_1 PF00133.17 EMC83994.1 - 5.4e-237 787.6 0.0 1e-236 786.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMC83994.1 - 3e-26 91.9 0.3 8.4e-26 90.5 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMC83994.1 - 7e-18 64.4 0.9 8.3e-06 24.6 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EMC83994.1 - 0.012 14.7 0.0 0.055 12.5 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain SNF PF00209.13 EMC83995.1 - 9.3e-248 822.9 38.0 1.1e-247 822.6 26.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 EMC83996.1 - 6e-234 777.3 41.2 6.9e-234 777.1 28.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 7tm_1 PF00001.16 EMC83997.1 - 1.2e-67 227.7 10.1 2.3e-67 226.8 7.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC83997.1 - 4e-10 39.2 16.3 4.3e-06 26.0 6.8 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC83997.1 - 0.0025 16.9 9.9 0.0025 16.9 6.9 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.4 EMC83997.1 - 0.011 14.3 0.0 0.59 8.6 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ninjurin PF04923.7 EMC83998.1 - 4e-36 122.8 5.6 4.6e-36 122.7 3.9 1.0 1 0 0 1 1 1 1 Ninjurin Cation_efflux PF01545.16 EMC83998.1 - 0.078 12.0 1.8 0.089 11.8 1.3 1.1 1 0 0 1 1 1 0 Cation efflux family I_LWEQ PF01608.12 EMC83999.1 - 0.068 13.1 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 I/LWEQ domain CARD PF00619.16 EMC84000.1 - 5.7e-08 32.4 0.1 1e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain NADH5_C PF06455.6 EMC84000.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus DUF3632 PF12311.3 EMC84000.1 - 0.14 11.9 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Sushi PF00084.15 EMC84001.1 - 2.1e-06 27.9 0.3 3.7e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Shisa PF13908.1 EMC84001.1 - 0.0024 18.0 0.1 0.0029 17.8 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EMC84001.1 - 0.032 14.6 0.1 0.05 14.0 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EMC84001.1 - 0.033 13.0 0.0 0.039 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2668 PF10873.3 EMC84001.1 - 0.038 14.1 0.8 0.047 13.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) TraL PF07178.6 EMC84001.1 - 0.11 12.4 0.1 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TraL protein IncA PF04156.9 EMC84001.1 - 1.2 8.7 3.6 2.5 7.6 2.5 1.5 1 1 0 1 1 1 0 IncA protein RhoGEF PF00621.15 EMC84002.1 - 1.4e-47 161.8 0.5 1.4e-47 161.8 0.3 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EMC84002.1 - 7.4e-19 67.8 0.4 1.7e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 PH domain FYVE PF01363.16 EMC84002.1 - 1.2e-14 53.9 14.7 9.9e-14 51.0 10.2 2.4 2 0 0 2 2 2 1 FYVE zinc finger PH_11 PF15413.1 EMC84002.1 - 0.0011 19.1 1.1 0.018 15.3 0.0 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 EMC84002.1 - 0.013 15.6 1.7 3 8.0 0.1 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.2 EMC84002.1 - 0.018 14.9 0.2 0.27 11.1 0.1 2.4 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology FYVE_2 PF02318.11 EMC84002.1 - 6 6.7 24.1 0.088 12.7 9.8 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger DZR PF12773.2 EMC84002.1 - 9.2 6.1 18.8 53 3.7 2.6 2.7 1 1 1 2 2 2 0 Double zinc ribbon C1-set PF07654.10 EMC84003.1 - 3.2e-20 71.9 0.0 7.4e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.13 EMC84003.1 - 3.8e-09 36.1 0.0 5.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_2 PF13895.1 EMC84003.1 - 2e-05 24.6 0.0 5.7e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC84003.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC84003.1 - 0.0079 16.0 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain C1-set PF07654.10 EMC84004.1 - 3.9e-20 71.6 0.0 7.2e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 EMC84004.1 - 3e-05 24.0 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC84004.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC84004.1 - 0.0096 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain C1-set PF07654.10 EMC84005.1 - 4.6e-20 71.4 0.0 8.2e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.13 EMC84005.1 - 2.9e-07 30.0 0.0 4.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_2 PF13895.1 EMC84005.1 - 3.2e-05 23.9 0.0 6.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC84005.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC84005.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Marek_A PF02124.10 EMC84005.1 - 0.068 12.6 0.5 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Marek's disease glycoprotein A DAGK_acc PF00609.14 EMC84006.1 - 1.8e-47 161.5 0.0 2.6e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Ank_2 PF12796.2 EMC84006.1 - 6.4e-32 109.7 7.3 2.1e-14 53.6 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC84006.1 - 1.2e-12 47.5 0.2 8.7e-07 29.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC84006.1 - 2.8e-12 45.8 1.3 1.4e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC84006.1 - 1.4e-11 44.6 0.0 2.7e-07 30.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84006.1 - 8.9e-10 37.8 1.5 0.00077 19.4 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat PTN_MK_C PF01091.13 EMC84007.1 - 2.1e-28 98.0 4.6 2.1e-28 98.0 3.2 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.8 EMC84007.1 - 4.3e-28 97.0 18.0 4.3e-28 97.0 12.5 2.3 2 1 0 2 2 2 1 PTN/MK heparin-binding protein family, N-terminal domain 7tm_1 PF00001.16 EMC84008.1 - 4.9e-81 271.6 6.6 7.3e-81 271.0 4.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RAG2 PF03089.9 EMC84008.1 - 0.016 13.9 0.7 0.025 13.3 0.5 1.2 1 0 0 1 1 1 0 Recombination activating protein 2 OGFr_III PF04680.8 EMC84009.1 - 0.063 13.4 2.1 0.094 12.8 1.5 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor repeat MIP-T3 PF10243.4 EMC84009.1 - 0.75 8.1 91.2 0.95 7.8 63.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ank_2 PF12796.2 EMC84010.1 - 2.7e-24 85.3 0.0 3.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC84010.1 - 6.2e-22 76.2 0.0 2e-09 36.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMC84010.1 - 1.3e-20 73.3 0.1 9e-12 45.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC84010.1 - 1.4e-19 69.6 0.1 1.7e-10 40.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84010.1 - 3.7e-16 57.6 0.1 2e-07 30.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Glyco_transf_8 PF01501.15 EMC84011.1 - 2.3e-45 154.9 0.0 2.8e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 CBFD_NFYB_HMF PF00808.18 EMC84012.1 - 5.7e-29 99.9 0.5 8.6e-29 99.4 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC84012.1 - 1.2e-06 28.5 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EMC84012.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EMC84012.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EMC84012.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Pyr_redox_2 PF07992.9 EMC84013.1 - 7.3e-40 136.9 0.2 9.5e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMC84013.1 - 9.3e-28 96.4 0.0 3.2e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMC84013.1 - 1e-17 64.2 3.4 2.2e-14 53.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC84013.1 - 8.9e-10 38.9 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC84013.1 - 4.6e-06 25.7 0.3 1.7e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMC84013.1 - 1.8e-05 23.4 0.1 0.00033 19.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EMC84013.1 - 0.00043 19.4 0.0 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMC84013.1 - 0.0014 17.7 1.2 0.002 17.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EMC84013.1 - 0.002 17.0 0.2 0.004 16.0 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EMC84013.1 - 0.0025 17.8 0.2 0.0025 17.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC84013.1 - 0.004 16.0 0.0 0.004 16.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EMC84013.1 - 0.037 14.2 1.8 6 7.1 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding Ank PF00023.25 EMC84015.1 - 6.5e-40 132.9 3.7 3.9e-09 35.8 0.3 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMC84015.1 - 4.2e-37 126.3 4.1 1.4e-20 73.4 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC84015.1 - 2.2e-31 107.1 13.2 5.3e-11 42.3 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC84015.1 - 1.1e-28 99.0 2.8 5.1e-11 42.7 0.1 4.0 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84015.1 - 2.2e-27 92.3 3.3 2.4e-05 24.1 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat DnaJ PF00226.26 EMC84016.1 - 1.1e-28 98.7 2.4 1.7e-28 98.1 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 EMC84017.1 - 1.3e-44 152.2 24.5 1.7e-44 151.9 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC84017.1 - 0.00071 18.8 24.6 0.0015 17.7 17.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Patatin PF01734.17 EMC84018.1 - 3.3e-24 85.9 0.0 5.5e-23 81.9 0.0 2.7 3 0 0 3 3 3 1 Patatin-like phospholipase COG2 PF06148.6 EMC84018.1 - 0.018 14.8 0.2 0.018 14.8 0.1 2.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3683 PF12447.3 EMC84018.1 - 1.6 8.6 7.8 3.5 7.4 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3683) I-set PF07679.11 EMC84019.1 - 1.8e-70 232.7 0.0 1.6e-12 47.0 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.16 EMC84019.1 - 2.2e-62 207.1 15.2 2.7e-14 53.0 0.1 5.5 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.1 EMC84019.1 - 5.4e-55 183.4 0.1 2.6e-09 37.0 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 EMC84019.1 - 1.2e-48 163.3 0.8 6.3e-07 29.7 0.0 7.6 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.20 EMC84019.1 - 1e-31 108.8 0.0 5e-06 26.5 0.0 8.0 7 0 0 7 7 7 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 EMC84019.1 - 1.7e-30 105.7 9.0 3.3e-30 104.8 6.3 1.5 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 EMC84019.1 - 4.7e-16 58.6 4.1 0.022 14.6 0.2 8.3 5 5 0 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC84019.1 - 6.7e-14 51.5 0.2 0.031 14.1 0.0 6.4 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 EMC84019.1 - 0.00049 19.8 1.4 4.8 6.9 0.0 3.8 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain BiPBP_C PF06832.7 EMC84019.1 - 0.0012 18.7 0.0 3.7 7.5 0.0 3.3 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family Herpes_gE PF02480.11 EMC84019.1 - 0.0035 15.6 0.0 0.91 7.7 0.0 3.7 4 0 0 4 4 4 1 Alphaherpesvirus glycoprotein E LST1 PF05083.8 EMC84019.1 - 0.21 11.5 0.4 99 3.0 0.0 3.8 4 0 0 4 4 4 0 LST-1 protein PT PF04886.7 EMC84020.1 - 4.2e-06 25.9 7.8 0.015 14.5 0.5 3.8 2 1 1 3 3 3 3 PT repeat Ank_2 PF12796.2 EMC84021.1 - 8.4e-114 372.1 28.9 5.4e-22 77.9 0.3 8.8 2 1 7 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EMC84021.1 - 6.7e-93 300.1 26.2 1.6e-08 33.9 0.0 16.0 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.1 EMC84021.1 - 2e-77 254.3 18.7 2.9e-12 46.7 0.1 11.1 6 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC84021.1 - 9.1e-69 225.9 25.0 4e-11 42.7 0.1 12.6 4 4 7 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84021.1 - 1.4e-67 216.8 19.6 0.00018 21.4 0.0 16.2 16 0 0 16 16 16 14 Ankyrin repeat IQ PF00612.22 EMC84021.1 - 3.2e-07 29.3 9.1 0.0027 17.2 0.8 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif PAS PF00989.19 EMC84022.1 - 6.5e-11 42.0 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EMC84022.1 - 1.1e-06 28.5 0.6 0.0012 18.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain HLH PF00010.21 EMC84022.1 - 5.2e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.6 EMC84022.1 - 6.1e-05 23.0 0.5 0.052 13.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EMC84022.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold EF-hand_1 PF00036.27 EMC84023.1 - 9.4e-26 87.1 3.0 1.9e-07 29.8 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EMC84023.1 - 2.7e-22 78.6 4.2 5.8e-12 45.5 0.7 3.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EMC84023.1 - 1.2e-21 74.6 2.2 1.2e-06 27.8 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.1 EMC84023.1 - 3.7e-20 71.2 4.9 1.5e-06 27.7 0.0 5.0 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 EMC84023.1 - 3.3e-12 45.1 2.9 0.00057 19.1 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EMC84023.1 - 0.052 13.4 0.1 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 EMC84023.1 - 0.086 12.5 0.1 2.6 7.7 0.0 3.0 4 0 0 4 4 4 0 EF hand Sec6 PF06046.8 EMC84024.1 - 1.1e-156 522.3 14.9 1.1e-156 522.3 10.3 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Dynein_heavy PF03028.10 EMC84025.1 - 1.1e-213 711.2 0.9 3e-213 709.8 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 EMC84025.1 - 5.4e-125 417.9 28.5 5.4e-125 417.9 19.8 3.1 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EMC84025.1 - 1.8e-113 379.1 14.1 1.8e-113 379.1 9.8 5.0 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EMC84025.1 - 5e-95 317.4 0.1 1.4e-94 315.9 0.1 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EMC84025.1 - 5.8e-71 238.5 0.1 2.4e-70 236.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EMC84025.1 - 3.9e-60 202.5 1.2 3e-59 199.6 0.9 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 EMC84025.1 - 1.9e-52 178.0 0.0 5.3e-52 176.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 EMC84025.1 - 4.8e-42 143.9 9.2 1.5e-41 142.3 6.4 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EMC84025.1 - 1.2e-20 73.6 0.0 2.9e-06 27.0 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 EMC84025.1 - 9.5e-07 29.0 0.1 1.6 8.9 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC84025.1 - 4.8e-05 23.4 0.0 2.1 8.2 0.0 4.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EMC84025.1 - 0.0061 16.7 4.7 5.5 7.1 0.0 6.0 7 0 0 7 7 7 1 AAA domain ZYG-11_interact PF05884.7 EMC84025.1 - 0.16 10.9 0.0 0.42 9.6 0.0 1.6 1 0 0 1 1 1 0 Interactor of ZYG-11 AAA_17 PF13207.1 EMC84025.1 - 0.21 12.4 0.9 28 5.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain PTRF_SDPR PF15237.1 EMC84026.1 - 6e-87 291.1 16.7 8.1e-87 290.6 11.5 1.2 1 0 0 1 1 1 1 PTRF/SDPR family Vac_Fusion PF02346.11 EMC84026.1 - 0.099 12.0 2.5 1.1 8.6 0.1 2.7 2 0 0 2 2 2 0 Chordopoxvirus fusion protein MCPsignal PF00015.16 EMC84026.1 - 0.48 9.9 16.2 0.094 12.2 2.4 2.8 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 EMC84026.1 - 1.3 8.8 10.2 0.41 10.4 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EMC84026.1 - 1.9 8.9 12.2 0.77 10.1 0.5 3.2 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Kazal_2 PF07648.10 EMC84027.1 - 3.2e-19 68.5 14.0 5.1e-12 45.5 2.2 3.7 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC84027.1 - 3.9e-17 61.9 26.4 5.4e-10 39.1 6.0 3.9 2 2 0 2 2 2 2 Kazal-type serine protease inhibitor domain hEGF PF12661.2 EMC84027.1 - 0.002 18.1 3.3 0.002 18.1 2.3 3.6 3 0 0 3 3 3 1 Human growth factor-like EGF EphA2_TM PF14575.1 EMC84027.1 - 0.043 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 EMC84027.1 - 0.062 12.9 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protocadherin DUF3628 PF12300.3 EMC84027.1 - 0.15 12.1 0.4 0.24 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) DUF4258 PF14076.1 EMC84027.1 - 5.6 7.0 6.3 36 4.4 0.3 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4258) Syndecan PF01034.15 EMC84027.1 - 7.5 6.2 7.2 2.4 7.8 1.8 2.1 2 0 0 2 2 2 0 Syndecan domain IQ PF00612.22 EMC84032.1 - 0.046 13.3 3.9 0.22 11.2 2.7 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif HEAT_EZ PF13513.1 EMC84032.1 - 0.12 12.8 3.6 0.23 11.9 0.8 2.9 2 0 0 2 2 2 0 HEAT-like repeat IMD PF08397.6 EMC84034.1 - 1.2e-67 227.4 10.1 6.1e-63 212.0 5.2 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain SH3_9 PF14604.1 EMC84034.1 - 4.1e-10 39.0 0.0 7.5e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC84034.1 - 8.1e-08 31.6 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC84034.1 - 1.1e-05 24.6 0.0 2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EMC84034.1 - 0.033 13.7 5.5 0.054 12.9 3.8 1.4 1 0 0 1 1 1 0 BAR domain Vezatin PF12632.2 EMC84034.1 - 0.052 12.6 1.7 0.099 11.7 1.2 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Snf7 PF03357.16 EMC84035.1 - 2.7e-20 72.4 4.7 2.7e-20 72.4 3.3 1.9 2 0 0 2 2 2 1 Snf7 Raptor_N PF14538.1 EMC84036.1 - 6.8e-60 201.3 0.3 3.8e-59 198.9 0.2 2.2 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 EMC84036.1 - 2.3e-15 55.2 1.7 0.00019 21.2 0.0 6.0 5 0 0 5 5 5 3 HEAT repeat WD40 PF00400.27 EMC84036.1 - 3.5e-11 42.5 15.7 0.0056 16.5 0.1 7.6 9 0 0 9 9 9 3 WD domain, G-beta repeat HEAT_2 PF13646.1 EMC84036.1 - 5.3e-11 42.6 0.3 5.8e-06 26.4 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EMC84036.1 - 2.7e-06 27.3 0.4 0.1 12.4 0.0 3.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EMC84036.1 - 1.4e-05 25.4 0.7 0.12 12.8 0.0 4.1 4 0 0 4 4 4 2 HEAT-like repeat Arm PF00514.18 EMC84036.1 - 0.01 15.6 0.1 0.18 11.6 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EMC84036.1 - 0.064 13.1 0.0 0.94 9.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 EMC84036.1 - 0.21 9.8 0.0 0.83 7.9 0.0 1.8 1 1 0 1 1 1 0 Adaptin N terminal region Pentaxin PF00354.12 EMC84037.1 - 6.1e-37 126.9 0.0 7.9e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 EMC84037.1 - 2.8e-17 63.3 0.1 3.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EMC84037.1 - 0.0061 16.6 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Endonuclease_5 PF04493.9 EMC84039.1 - 6.9e-58 195.4 0.0 7.7e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V Sulfatase PF00884.18 EMC84040.1 - 1e-48 166.0 0.0 3.5e-48 164.3 0.0 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMC84040.1 - 6.2e-11 42.2 0.0 3.3e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EMC84040.1 - 0.013 15.7 0.3 0.026 14.7 0.2 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF2264 PF10022.4 EMC84040.1 - 0.027 13.1 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) BRE1 PF08647.6 EMC84041.1 - 3.1e-08 33.4 14.6 3.1e-08 33.4 10.1 10.6 5 4 2 9 9 9 2 BRE1 E3 ubiquitin ligase DUF2070 PF09843.4 EMC84041.1 - 0.0063 16.0 0.0 0.074 12.5 0.0 2.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) Reo_sigmaC PF04582.7 EMC84041.1 - 1.2 8.2 19.6 2.6 7.1 0.1 5.2 3 2 1 5 5 5 0 Reovirus sigma C capsid protein RabGAP-TBC PF00566.13 EMC84042.1 - 8.9e-36 123.3 6.8 2.9e-35 121.7 4.7 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Phosphodiest PF01663.17 EMC84045.1 - 6e-44 150.8 0.2 7.5e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMC84045.1 - 2e-08 33.9 0.0 2.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EMC84045.1 - 0.00031 20.0 0.1 0.00076 18.7 0.0 1.8 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.7 EMC84045.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 PglZ domain Fox-1_C PF12414.3 EMC84046.1 - 5.3e-37 126.1 20.8 1.3e-24 86.4 5.1 3.3 3 0 0 3 3 3 2 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 EMC84046.1 - 3.5e-19 68.2 1.0 4.5e-19 67.8 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84046.1 - 6.1e-15 54.9 0.1 9.6e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC84046.1 - 2.2e-10 40.2 0.1 4.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC84046.1 - 0.06 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif C1q PF00386.16 EMC84047.1 - 2e-37 128.0 1.4 2.5e-37 127.7 1.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC84047.1 - 1.8e-08 33.8 13.0 2.6e-08 33.2 9.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Apyrase PF06079.6 EMC84048.1 - 4.4e-75 252.5 0.1 5.2e-75 252.3 0.1 1.0 1 0 0 1 1 1 1 Apyrase TIMP PF00965.12 EMC84049.1 - 3.4e-32 111.4 8.3 3.8e-32 111.3 5.8 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase UCH PF00443.24 EMC84050.1 - 1e-57 195.3 0.0 1.2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC84050.1 - 5.1e-24 85.2 0.0 6.5e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ig_2 PF13895.1 EMC84050.1 - 0.051 13.6 0.5 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Sec7 PF01369.15 EMC84052.1 - 6.4e-71 237.9 0.2 9.7e-71 237.3 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EMC84052.1 - 1.4e-25 89.4 0.1 2.6e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC84052.1 - 2.1e-07 31.1 1.1 1.4e-06 28.5 0.7 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMC84052.1 - 0.002 17.9 0.2 0.013 15.3 0.1 2.2 1 1 0 1 1 1 1 PH domain BBS2_C PF14782.1 EMC84052.1 - 0.0043 15.6 0.8 0.28 9.7 0.3 2.1 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal PH_8 PF15409.1 EMC84052.1 - 0.0099 15.9 0.0 0.091 12.8 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain DASH_Spc34 PF08657.5 EMC84052.1 - 0.033 13.8 1.3 0.059 13.0 0.9 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 APG6 PF04111.7 EMC84052.1 - 0.13 11.2 2.9 0.23 10.4 2.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 EMC84052.1 - 0.16 11.7 5.7 1.3 8.8 3.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EMC84052.1 - 0.2 11.1 1.6 0.42 10.1 1.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Syntaxin-6_N PF09177.6 EMC84052.1 - 0.24 11.8 2.2 21 5.5 0.0 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal IncA PF04156.9 EMC84052.1 - 0.31 10.5 1.7 0.54 9.8 1.2 1.3 1 0 0 1 1 1 0 IncA protein PLDc_2 PF13091.1 EMC84053.1 - 8.6e-15 54.5 0.0 5e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC84053.1 - 0.75 9.6 3.2 4.7 7.1 0.1 2.7 3 0 0 3 3 3 0 Phospholipase D Active site motif SH2 PF00017.19 EMC84054.1 - 2.5e-10 40.0 0.0 5.2e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 EMC84054.1 - 2.4e-08 33.6 0.0 4.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SOCS box Abhydrolase_3 PF07859.8 EMC84055.1 - 1.3e-06 28.1 0.9 6.6e-06 25.8 0.7 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC84055.1 - 2.8e-05 23.8 0.8 0.00011 21.9 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC84055.1 - 0.00085 19.2 2.4 0.0017 18.3 1.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMC84055.1 - 0.0019 17.7 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2305 PF10230.4 EMC84055.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 EMC84055.1 - 0.015 14.5 0.0 0.029 13.5 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMC84055.1 - 0.063 12.8 0.1 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EMC84055.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) MARVEL PF01284.18 EMC84056.1 - 1.3e-17 63.9 15.8 1.7e-17 63.6 11.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Arf PF00025.16 EMC84057.1 - 4.6e-09 35.7 0.0 5.4e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family STAS_2 PF13466.1 EMC84057.1 - 0.077 13.0 1.1 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 STAS domain Hrs_helical PF12210.3 EMC84058.1 - 1.4e-44 150.2 3.1 1.4e-44 150.2 2.2 2.5 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate VHS PF00790.14 EMC84058.1 - 1e-32 112.6 1.6 2.8e-32 111.2 1.1 1.8 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 EMC84058.1 - 1.9e-18 66.1 10.0 4.5e-18 64.9 6.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EMC84058.1 - 0.0062 16.0 6.4 0.022 14.2 4.5 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4575 PF15143.1 EMC84058.1 - 0.074 12.7 0.1 0.074 12.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4575) DUF3608 PF12257.3 EMC84058.1 - 0.16 10.8 3.1 2.2 7.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3608) Mito_carr PF00153.22 EMC84059.1 - 4.2e-33 112.9 4.7 1.4e-12 47.1 0.0 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein 7tm_2 PF00002.19 EMC84061.1 - 1.1e-79 266.9 21.6 1.4e-79 266.6 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC84061.1 - 1.8e-15 56.6 3.5 1.8e-15 56.6 2.4 1.7 2 0 0 2 2 2 1 Hormone receptor domain Ank PF00023.25 EMC84062.1 - 5.1e-13 48.1 1.3 1.2e-08 34.3 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMC84062.1 - 1.3e-12 47.8 0.0 1.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC84062.1 - 1.6e-12 47.5 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC84062.1 - 1.7e-11 43.9 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84062.1 - 2.3e-07 30.3 0.3 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Thioredoxin_6 PF13848.1 EMC84063.1 - 1.7e-47 161.6 2.1 1.7e-44 151.8 1.2 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 EMC84063.1 - 4.1e-31 106.7 0.1 3.6e-29 100.4 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.1 EMC84063.1 - 1.4e-06 28.3 0.0 0.00017 21.6 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like ERp29_N PF07912.8 EMC84063.1 - 4.1e-06 26.7 0.4 1.1 9.1 0.0 3.3 3 0 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_2 PF13098.1 EMC84063.1 - 1.2e-05 25.5 0.1 0.00016 21.8 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC84063.1 - 3.8e-05 23.6 0.0 0.00027 20.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 EMC84063.1 - 0.00038 20.0 0.2 0.035 13.6 0.0 2.4 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EMC84063.1 - 0.0038 16.9 0.2 0.16 11.6 0.0 2.7 3 0 0 3 3 3 1 AhpC/TSA family Rho_GDI PF02115.12 EMC84065.1 - 1.5e-72 243.1 0.8 1.1e-48 165.3 0.0 2.0 1 1 1 2 2 2 2 RHO protein GDP dissociation inhibitor DUF4289 PF14121.1 EMC84065.1 - 0.084 11.2 0.0 0.084 11.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4289) RRM_1 PF00076.17 EMC84066.1 - 3.3e-09 36.2 0.0 4.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC84066.1 - 3.8e-08 33.0 0.0 6.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84066.1 - 4e-07 29.9 0.0 6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EMC84066.1 - 1.5e-06 28.5 11.1 4.2e-06 27.1 7.7 1.8 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 zf-Apc11 PF12861.2 EMC84067.1 - 8.3e-26 89.6 14.6 9e-26 89.5 10.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMC84067.1 - 6.3e-19 67.8 14.9 6.9e-19 67.7 10.4 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMC84067.1 - 5.9e-06 26.0 22.6 2.3e-05 24.1 15.7 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC84067.1 - 0.0034 17.3 15.4 0.0057 16.6 10.7 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC84067.1 - 0.011 15.3 12.3 0.011 15.3 8.5 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84067.1 - 0.55 10.0 18.7 1.7 8.4 13.1 1.7 1 1 1 2 2 2 0 zinc-RING finger domain Opy2 PF09463.5 EMC84067.1 - 1.3 9.1 15.2 0.68 10.0 6.1 2.1 2 0 0 2 2 2 0 Opy2 protein zf-C3HC4_3 PF13920.1 EMC84067.1 - 1.7 8.3 18.6 6 6.6 12.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EMC84067.1 - 3.8 7.0 11.2 5.2 6.6 7.8 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tax PF02959.11 EMC84067.1 - 4.7 6.6 7.1 5 6.5 4.9 1.1 1 0 0 1 1 1 0 HTLV Tax CTP_transf_2 PF01467.21 EMC84069.1 - 5.6e-31 107.7 0.1 1.4e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EMC84069.1 - 0.0034 17.0 1.1 0.12 11.9 0.0 2.9 3 0 0 3 3 3 1 FAD synthetase CHAP PF05257.11 EMC84069.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CHAP domain SIR2 PF02146.12 EMC84070.1 - 2e-28 99.3 2.0 1.7e-22 79.9 0.4 2.0 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 EMC84070.1 - 0.049 13.3 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain bZIP_Maf PF03131.12 EMC84071.1 - 9.1e-34 115.6 11.7 1.2e-33 115.3 8.1 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 EMC84071.1 - 8.4e-05 21.9 5.8 8.4e-05 21.9 4.0 2.2 1 1 1 2 2 2 1 Septum formation initiator ERM PF00769.14 EMC84071.1 - 0.00071 19.1 2.4 0.00083 18.9 1.7 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family bZIP_1 PF00170.16 EMC84071.1 - 0.0009 19.1 16.1 0.013 15.4 11.2 2.3 1 1 0 1 1 1 1 bZIP transcription factor DUF2046 PF09755.4 EMC84071.1 - 0.0038 16.1 1.0 0.0038 16.1 0.7 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF1192 PF06698.6 EMC84071.1 - 0.0047 16.7 7.6 0.052 13.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF342 PF03961.8 EMC84071.1 - 0.011 14.1 4.8 0.015 13.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 EMC84071.1 - 0.012 15.9 3.6 0.012 15.9 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EMC84071.1 - 0.013 14.5 7.4 0.015 14.3 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 EMC84071.1 - 0.032 13.9 1.1 0.032 13.9 0.8 1.6 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 Tox-ODYAM1 PF15642.1 EMC84071.1 - 0.038 12.6 3.3 0.049 12.3 2.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus HTH_Crp_2 PF13545.1 EMC84071.1 - 0.06 13.1 0.4 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HALZ PF02183.13 EMC84071.1 - 0.066 12.9 9.1 0.074 12.7 2.4 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4164 PF13747.1 EMC84071.1 - 0.11 12.6 8.4 0.25 11.4 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) HGTP_anticodon2 PF12745.2 EMC84071.1 - 0.11 11.5 3.0 0.16 11.1 2.1 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs M_domain PF12938.2 EMC84071.1 - 0.15 11.8 1.6 0.23 11.2 1.1 1.4 1 1 0 1 1 1 0 M domain of GW182 Atg14 PF10186.4 EMC84071.1 - 0.18 10.6 8.4 0.22 10.4 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FimP PF09766.4 EMC84071.1 - 0.19 10.7 5.3 0.23 10.4 3.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein bZIP_2 PF07716.10 EMC84071.1 - 0.21 11.4 16.9 0.06 13.1 8.0 2.6 1 1 2 3 3 3 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 EMC84071.1 - 0.25 11.1 11.9 0.05 13.4 3.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EMC84071.1 - 0.25 10.8 12.2 2.2 7.8 8.5 2.0 1 1 0 1 1 1 0 IncA protein Kinesin-relat_1 PF12711.2 EMC84071.1 - 0.29 11.5 7.5 0.068 13.5 2.1 2.0 2 0 0 2 2 2 0 Kinesin motor DUF3584 PF12128.3 EMC84071.1 - 0.35 8.1 8.1 0.38 8.0 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rop-like PF05082.8 EMC84071.1 - 0.38 10.2 3.7 0.19 11.2 0.6 2.0 2 0 0 2 2 2 0 Rop-like Mnd1 PF03962.10 EMC84071.1 - 0.49 10.0 7.6 0.71 9.5 5.3 1.3 1 0 0 1 1 1 0 Mnd1 family Nnf1 PF03980.9 EMC84071.1 - 0.63 10.0 7.1 2.1 8.3 4.9 1.8 1 1 0 1 1 1 0 Nnf1 V_ATPase_I PF01496.14 EMC84071.1 - 0.69 7.6 2.5 0.81 7.4 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.3 EMC84071.1 - 0.84 8.9 8.8 1.9 7.8 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DASH_Spc19 PF08287.6 EMC84071.1 - 1.1 8.8 10.1 1.6 8.3 7.0 1.2 1 0 0 1 1 1 0 Spc19 NUDE_C PF04880.8 EMC84071.1 - 2 8.7 8.7 3 8.1 0.8 2.1 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region NYD-SP28_assoc PF14775.1 EMC84071.1 - 2.1 8.0 6.0 0.69 9.6 1.4 2.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain Mst1_SARAH PF11629.3 EMC84071.1 - 2.5 7.9 9.5 15 5.4 1.9 2.9 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Seryl_tRNA_N PF02403.17 EMC84071.1 - 2.6 8.0 9.8 4.3 7.4 6.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 EMC84071.1 - 3 8.1 5.9 3.8 7.7 4.1 1.2 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.9 EMC84071.1 - 3.3 7.2 9.3 5.6 6.5 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4140 PF13600.1 EMC84071.1 - 3.3 8.2 9.7 2 8.9 2.9 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF465 PF04325.8 EMC84071.1 - 3.5 7.3 8.1 7.7 6.3 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF465) DUF3086 PF11285.3 EMC84071.1 - 5.1 5.8 7.1 2.3 6.9 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DUF904 PF06005.7 EMC84071.1 - 5.2 7.4 13.3 44 4.4 9.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Bap31 PF05529.7 EMC84071.1 - 6.8 6.0 9.5 10 5.5 6.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like OmpH PF03938.9 EMC84071.1 - 7.7 6.4 12.0 14 5.6 8.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) P5CR_dimer PF14748.1 EMC84072.1 - 1.3e-39 134.4 0.0 2.3e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMC84072.1 - 1.4e-08 35.0 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EMC84072.1 - 0.00025 20.8 0.1 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EMC84072.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UBX PF00789.15 EMC84073.1 - 9.7e-13 47.9 0.0 2.2e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.3 EMC84073.1 - 1.2e-05 25.1 0.1 2.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG DUF1192 PF06698.6 EMC84073.1 - 0.032 14.0 0.1 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) LRR_6 PF13516.1 EMC84075.1 - 2.6e-10 39.2 11.3 0.017 15.1 0.1 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 EMC84075.1 - 4.9e-08 31.9 1.6 1 9.6 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 EMC84075.1 - 5.1e-07 29.1 11.9 0.0071 15.9 2.0 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC84075.1 - 1.5e-05 24.6 13.6 0.004 16.8 1.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EMC84075.1 - 0.0016 18.3 8.0 8.4 7.0 0.1 5.7 5 0 0 5 5 5 2 Leucine rich repeat RPN7 PF10602.4 EMC84076.1 - 1.6e-72 242.5 0.5 2.8e-72 241.7 0.3 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EMC84076.1 - 1.9e-17 63.5 1.2 8e-17 61.4 0.1 2.3 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 EMC84076.1 - 0.00047 19.7 0.2 0.17 11.5 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC84076.1 - 0.0032 17.2 4.6 0.14 12.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC84076.1 - 0.067 12.8 5.2 0.15 11.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TLV_coat PF00429.14 EMC84078.1 - 0.0078 14.7 0.6 0.0086 14.5 0.4 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) TRIC PF05197.8 EMC84079.1 - 1.1e-90 302.3 4.7 1.3e-90 302.1 3.2 1.1 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.8 EMC84079.1 - 0.0022 17.5 3.2 0.41 10.3 0.0 2.7 2 1 0 2 2 2 2 UPF0126 domain HLH PF00010.21 EMC84080.1 - 2.9e-17 62.1 0.8 3.9e-17 61.6 0.6 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PMBR PF09373.5 EMC84080.1 - 0.01 15.7 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Pseudomurein-binding repeat zf-RING_2 PF13639.1 EMC84081.1 - 2.7e-11 43.1 9.4 5.2e-11 42.1 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC84081.1 - 4.2e-11 42.3 8.7 7.4e-11 41.5 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84081.1 - 5.4e-10 39.1 9.9 1e-09 38.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC84081.1 - 2.7e-09 36.5 7.6 4.8e-09 35.7 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84081.1 - 1e-07 31.5 6.1 1.9e-07 30.7 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC84081.1 - 0.00012 22.1 8.8 0.00029 20.8 6.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC84081.1 - 0.0014 18.4 10.9 0.0028 17.4 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC84081.1 - 0.0033 17.0 6.7 0.007 16.0 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EMC84081.1 - 0.012 15.2 3.5 0.02 14.5 2.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 EMC84081.1 - 0.017 14.9 5.0 0.043 13.6 3.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EMC84081.1 - 0.19 11.2 0.5 19 4.8 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 EMC84081.1 - 0.24 11.2 2.8 0.53 10.0 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LicD PF04991.8 EMC84082.1 - 4.2e-13 49.8 1.2 6.1e-11 42.8 0.3 3.2 2 1 0 2 2 2 1 LicD family SPRY PF00622.23 EMC84083.1 - 4.3e-17 62.3 0.2 9.5e-17 61.2 0.2 1.5 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.16 EMC84083.1 - 4.1e-05 23.6 0.0 0.00017 21.6 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain LOH1CR12 PF10158.4 EMC84083.1 - 0.038 13.7 2.0 0.082 12.6 1.4 1.6 1 0 0 1 1 1 0 Tumour suppressor protein Bac_thur_toxin PF01338.13 EMC84083.1 - 0.04 13.1 1.4 0.049 12.8 0.0 1.8 2 0 0 2 2 2 0 Bacillus thuringiensis toxin NPV_P10 PF05531.7 EMC84083.1 - 0.15 12.3 3.5 2.8 8.2 0.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLYB PF05289.6 EMC84083.1 - 0.78 9.5 4.9 2 8.2 0.7 2.5 1 1 1 2 2 2 0 Borrelia hemolysin accessory protein Choline_transpo PF04515.7 EMC84085.1 - 6.3e-101 337.4 35.0 6.3e-101 337.4 24.2 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4131 PF13567.1 EMC84085.1 - 0.38 10.1 0.0 0.38 10.1 0.0 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) ABC2_membrane_3 PF12698.2 EMC84086.1 - 4.2e-56 190.4 48.8 1.5e-44 152.4 12.3 3.6 4 0 0 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.22 EMC84086.1 - 2.3e-52 176.9 0.0 1.1e-28 100.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMC84086.1 - 1.6e-19 70.9 0.0 3.3e-08 33.8 0.0 4.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMC84086.1 - 0.00059 19.3 1.9 0.054 13.0 0.3 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF4162 PF13732.1 EMC84086.1 - 0.0046 17.4 0.1 0.2 12.1 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_23 PF13476.1 EMC84086.1 - 0.011 16.1 6.4 0.029 14.6 0.4 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EMC84086.1 - 0.012 14.7 0.0 2.8 6.8 0.0 3.2 2 1 0 3 3 3 0 AAA ATPase domain SbcCD_C PF13558.1 EMC84086.1 - 0.015 15.2 0.0 8.6 6.3 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FAM180 PF15173.1 EMC84086.1 - 0.049 13.4 0.3 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 FAM180 family DUF258 PF03193.11 EMC84086.1 - 0.098 11.8 0.3 3.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NIPSNAP PF07978.8 EMC84087.1 - 8.3e-51 170.2 0.8 2e-27 95.1 0.2 2.0 2 0 0 2 2 2 2 NIPSNAP Esterase PF00756.15 EMC84087.1 - 0.019 14.3 0.4 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Ring_hydroxyl_A PF00848.14 EMC84087.1 - 0.072 12.7 0.3 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) Lipase PF00151.14 EMC84088.1 - 3.5e-107 358.4 0.0 4.4e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 EMC84088.1 - 4.2e-22 78.6 0.9 7.1e-22 77.9 0.6 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 EMC84088.1 - 4.1e-08 33.3 0.1 5.3e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC84088.1 - 0.00043 20.0 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family W2 PF02020.13 EMC84088.1 - 0.052 13.5 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon DUF2048 PF09752.4 EMC84088.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Neuregulin PF02158.10 EMC84089.1 - 2.6e-227 754.2 26.6 3.5e-227 753.8 18.4 1.1 1 0 0 1 1 1 1 Neuregulin family hEGF PF12661.2 EMC84089.1 - 0.021 14.8 1.6 0.021 14.8 1.1 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.22 EMC84089.1 - 0.38 10.7 3.6 1.1 9.3 2.5 1.8 1 0 0 1 1 1 0 EGF-like domain PPTA PF01239.17 EMC84090.1 - 1.6e-53 175.9 14.3 3.9e-12 44.9 0.2 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.1 EMC84090.1 - 0.59 10.9 3.0 76 4.3 0.1 4.1 4 2 1 6 6 6 0 Tetratricopeptide repeat zf-Di19 PF05605.7 EMC84091.1 - 5.7e-23 80.7 1.8 5.7e-23 80.7 1.3 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.12 EMC84091.1 - 1.4e-10 40.5 7.1 1.4e-10 40.5 4.9 2.4 3 0 0 3 3 3 1 Zinc finger, ZZ type Di19_C PF14571.1 EMC84091.1 - 0.004 17.4 4.1 0.004 17.4 2.8 2.5 1 1 1 2 2 2 1 Stress-induced protein Di19, C-terminal zf-C2H2 PF00096.21 EMC84091.1 - 0.012 15.8 0.3 0.012 15.8 0.2 3.3 3 1 0 3 3 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC84091.1 - 0.015 15.5 0.1 0.015 15.5 0.1 3.5 3 0 0 3 3 2 0 C2H2-type zinc finger Dicty_REP PF05086.7 EMC84091.1 - 0.072 10.8 3.7 0.094 10.4 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Elf1 PF05129.8 EMC84091.1 - 0.12 12.1 0.9 0.36 10.5 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 EMC84091.1 - 0.17 11.1 2.3 2.5 7.4 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 EMC84091.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.7 4 0 0 4 4 2 0 Zinc-finger double-stranded RNA-binding TFIIA PF03153.8 EMC84091.1 - 0.29 10.9 7.2 0.38 10.5 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mnd1 PF03962.10 EMC84091.1 - 3.7 7.1 7.8 5.7 6.5 5.4 1.2 1 0 0 1 1 1 0 Mnd1 family zf-LITAF-like PF10601.4 EMC84091.1 - 3.8 7.4 11.6 0.35 10.7 0.3 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.1 EMC84091.1 - 9.4 6.7 10.5 0.36 11.2 0.1 3.5 4 0 0 4 4 3 0 Zinc-finger double domain HOOK PF05622.7 EMC84092.1 - 1.7e-51 174.9 5.5 1.9e-51 174.8 3.8 1.0 1 0 0 1 1 1 1 HOOK protein DNA_pol_alpha_N PF12254.3 EMC84092.1 - 0.011 15.5 0.1 0.028 14.2 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal TEX13 PF15186.1 EMC84092.1 - 0.013 15.0 0.9 0.019 14.5 0.6 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF641 PF04859.7 EMC84092.1 - 0.08 12.7 2.8 0.11 12.2 2.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 EMC84092.1 - 0.12 11.7 2.5 0.16 11.4 1.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 CCDC-167 PF15188.1 EMC84092.1 - 0.13 12.2 3.9 0.19 11.6 2.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF228 PF02989.9 EMC84092.1 - 0.14 11.6 1.1 0.16 11.4 0.7 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Angiomotin_C PF12240.3 EMC84092.1 - 0.19 11.1 6.4 0.22 10.9 4.4 1.2 1 1 0 1 1 1 0 Angiomotin C terminal YkyA PF10368.4 EMC84092.1 - 0.2 10.9 4.7 0.42 9.9 3.3 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF342 PF03961.8 EMC84092.1 - 0.48 8.7 3.1 0.5 8.7 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 EMC84092.1 - 1.2 8.6 5.8 1.6 8.1 4.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like OmpH PF03938.9 EMC84092.1 - 3.3 7.6 8.8 4.1 7.3 6.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DALR_2 PF09190.6 EMC84093.1 - 2.4e-05 24.4 0.0 0.0012 18.9 0.0 2.7 2 0 0 2 2 2 1 DALR domain Carb_kinase PF01256.12 EMC84094.1 - 3.5e-55 186.9 0.0 4.1e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EMC84094.1 - 0.029 13.5 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Suc_Fer-like PF06999.7 EMC84094.1 - 0.063 13.2 0.1 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Ras PF00071.17 EMC84095.1 - 6.1e-30 103.7 0.0 1.8e-29 102.2 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC84095.1 - 4.5e-13 49.7 0.0 8.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC84095.1 - 7e-12 44.9 0.0 9.4e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC84095.1 - 0.00029 20.7 0.0 0.00056 19.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC84095.1 - 0.031 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit C4 PF01413.14 EMC84096.1 - 3.8e-92 303.8 3.3 1.3e-47 160.4 0.2 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen COMP PF11598.3 EMC84096.1 - 0.11 12.5 2.0 1.3 9.1 0.2 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Collagen PF01391.13 EMC84097.1 - 2.3e-30 103.8 95.9 5.4e-11 41.8 12.6 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Collagen PF01391.13 EMC84098.1 - 4.7e-204 660.2 759.4 5.2e-10 38.7 17.4 27.2 5 4 20 25 25 25 24 Collagen triple helix repeat (20 copies) C4 PF01413.14 EMC84098.1 - 2.4e-89 294.8 6.3 2.1e-49 166.1 0.4 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen EVE PF01878.13 EMC84099.1 - 0.027 14.5 8.2 9.8 6.1 0.0 3.9 1 1 3 4 4 4 0 EVE domain NT-C2 PF10358.4 EMC84099.1 - 0.14 11.6 1.1 8.3 5.9 0.0 2.9 3 2 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins SMN PF06003.7 EMC84099.1 - 1.3 8.0 22.0 3.4 6.7 5.4 2.1 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) Actin PF00022.14 EMC84100.1 - 1.3e-87 293.8 0.0 3.4e-87 292.4 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMC84100.1 - 2.7e-05 22.9 0.0 0.043 12.4 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.12 EMC84100.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain EamA PF00892.15 EMC84101.1 - 2.1e-10 40.6 35.4 4.8e-07 29.8 3.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EMC84101.1 - 0.0014 18.7 3.5 0.0014 18.7 2.4 3.7 3 2 1 4 4 4 1 Multidrug resistance efflux transporter DUF2637 PF10935.3 EMC84101.1 - 0.06 13.2 0.3 0.19 11.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2637) 7tm_1 PF00001.16 EMC84102.1 - 2.6e-36 125.0 6.8 2.6e-36 125.0 4.7 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC84102.1 - 2.7e-05 23.4 10.6 0.00016 20.9 0.9 2.5 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC84102.1 - 0.11 11.6 7.7 0.021 13.9 1.5 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx NCKAP5 PF15246.1 EMC84104.1 - 2.7e-28 99.2 1.3 3.5e-28 98.8 0.9 1.2 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein NCKAP5 PF15246.1 EMC84105.1 - 1.4e-77 261.2 17.2 1.4e-77 261.2 11.9 4.5 5 0 0 5 5 5 1 Nck-associated protein 5, Peripheral clock protein Glyco_transf_18 PF15024.1 EMC84106.1 - 9.8e-257 852.7 0.6 1.2e-256 852.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.1 EMC84106.1 - 1.8e-68 228.4 0.2 3.1e-68 227.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) Cation_efflux PF01545.16 EMC84107.1 - 0.0058 15.7 27.2 0.018 14.0 18.8 1.7 1 1 0 1 1 1 1 Cation efflux family Orbi_NS3 PF01616.11 EMC84107.1 - 0.044 12.7 1.9 3.1 6.7 0.3 2.3 2 0 0 2 2 2 0 Orbivirus NS3 EcsB PF05975.7 EMC84107.1 - 0.12 10.8 7.0 0.19 10.1 4.8 1.3 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF308 PF03729.8 EMC84107.1 - 0.46 10.5 19.5 2 8.4 5.9 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF1385 PF07136.6 EMC84107.1 - 0.78 8.7 5.9 3.5 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) MerC PF03203.9 EMC84107.1 - 0.92 9.8 15.5 0.53 10.6 1.6 2.4 2 1 0 2 2 2 0 MerC mercury resistance protein DUF3040 PF11239.3 EMC84107.1 - 2.2 8.4 14.1 2.9 8.0 1.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) Amidohydro_2 PF04909.9 EMC84108.1 - 4.4e-53 180.6 0.0 5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Pkinase PF00069.20 EMC84109.1 - 8.7e-56 188.9 0.0 9.8e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84109.1 - 8.2e-38 129.9 0.0 9.7e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC84109.1 - 1e-07 31.2 0.0 1.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC84109.1 - 0.0013 18.5 0.1 0.0042 16.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMC84109.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Rab3-GTPase_cat PF13890.1 EMC84110.1 - 1.4e-67 226.1 0.0 1.6e-66 222.7 0.0 2.4 3 0 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit UBX PF00789.15 EMC84111.1 - 2.7e-18 65.8 0.0 6.1e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain CAF-1_p150 PF11600.3 EMC84111.1 - 0.00016 21.1 36.3 0.00016 21.1 25.2 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_hydro_1 PF00232.13 EMC84112.1 - 0 1791.6 15.4 2.6e-176 586.2 2.1 4.1 4 0 0 4 4 4 4 Glycosyl hydrolase family 1 tRNA-synt_2 PF00152.15 EMC84113.1 - 6.4e-80 268.4 0.1 8.3e-80 268.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMC84113.1 - 3.4e-10 39.6 1.0 6.1e-10 38.8 0.7 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC84113.1 - 2.9e-05 23.3 0.4 0.27 10.3 0.2 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) S-AdoMet_synt_N PF00438.15 EMC84113.1 - 0.00089 19.4 0.4 0.0056 16.8 0.2 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain 7tm_1 PF00001.16 EMC84114.1 - 2.8e-57 193.7 14.8 3.4e-57 193.5 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.3 EMC84114.1 - 1.6e-19 69.4 5.1 2.4e-19 68.7 3.5 1.3 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.4 EMC84114.1 - 0.0023 17.1 14.6 0.0035 16.5 10.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC84114.1 - 0.014 15.1 3.2 0.014 15.1 2.2 2.7 1 1 1 2 2 2 0 Olfactory receptor CitMHS PF03600.11 EMC84114.1 - 1.1 7.7 8.1 0.37 9.3 0.8 2.0 2 0 0 2 2 2 0 Citrate transporter TSP_1 PF00090.14 EMC84115.1 - 2.3e-38 130.0 221.9 9.3e-09 35.2 5.5 23.0 23 3 0 23 23 23 14 Thrombospondin type 1 domain Methyltransf_23 PF13489.1 EMC84116.1 - 8.5e-14 51.5 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC84116.1 - 4.9e-05 22.9 0.0 8.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84116.1 - 0.0003 21.2 0.0 0.00048 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC84117.1 - 1.5e-18 67.0 0.0 2.4e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84117.1 - 6.3e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC84117.1 - 5.1e-05 22.9 0.0 7.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WIF PF02019.13 EMC84117.1 - 0.034 13.5 0.3 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 WIF domain Glutaredoxin PF00462.19 EMC84117.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin Methyltransf_11 PF08241.7 EMC84117.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain BTB PF00651.26 EMC84118.1 - 7.5e-35 119.2 0.9 8.4e-34 115.9 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.21 EMC84118.1 - 1.1e-09 38.5 0.2 3e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 MATH domain BTB_2 PF02214.17 EMC84118.1 - 0.00063 19.8 0.1 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 EMC84118.1 - 0.15 11.9 1.6 12 5.8 0.0 3.5 4 0 0 4 4 4 0 BTB And C-terminal Kelch Neurexophilin PF06312.7 EMC84119.1 - 8.8e-111 368.3 4.4 1.1e-110 368.0 3.0 1.0 1 0 0 1 1 1 1 Neurexophilin Nepo_coat_C PF03688.9 EMC84119.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain EGF PF00008.22 EMC84120.1 - 3.4e-12 46.0 170.9 0.00017 21.5 4.6 12.3 11 0 0 11 11 11 7 EGF-like domain VWD PF00094.20 EMC84120.1 - 2.2e-08 34.4 0.1 1.9e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type D domain EGF_2 PF07974.8 EMC84120.1 - 4e-05 23.6 188.5 0.0027 17.8 5.4 12.8 12 0 0 12 12 12 9 EGF-like domain hEGF PF12661.2 EMC84120.1 - 0.00035 20.4 89.0 0.045 13.8 2.2 12.0 10 0 0 10 10 10 6 Human growth factor-like EGF Ldl_recept_a PF00057.13 EMC84121.1 - 9.4e-289 930.9 618.3 1.9e-12 46.8 8.6 35.9 35 0 0 35 35 35 32 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 EMC84121.1 - 2.2e-179 581.5 90.3 1.8e-10 40.9 0.0 37.1 38 1 0 38 38 38 28 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 EMC84121.1 - 7.1e-58 192.4 364.3 3.2e-11 43.1 4.7 25.6 21 1 4 25 25 25 15 Coagulation Factor Xa inhibitory site SGL PF08450.7 EMC84121.1 - 3.5e-21 75.7 29.1 0.0017 17.8 0.1 14.9 10 5 4 15 15 15 5 SMP-30/Gluconolaconase/LRE-like region cEGF PF12662.2 EMC84121.1 - 9.4e-21 73.1 119.8 8.6e-09 34.8 0.4 16.9 15 0 0 15 15 15 8 Complement Clr-like EGF-like EGF PF00008.22 EMC84121.1 - 0.0017 18.2 4.2 0.0017 18.2 2.9 34.8 37 0 0 37 37 37 14 EGF-like domain Arylesterase PF01731.15 EMC84121.1 - 0.0032 17.4 0.1 1.2e+02 2.7 0.0 7.9 9 2 1 10 10 10 0 Arylesterase TMEM154 PF15102.1 EMC84121.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Aminotran_5 PF00266.14 EMC84122.1 - 8.5e-10 37.9 0.0 1.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V RhoGAP PF00620.22 EMC84123.1 - 1.8e-52 176.9 0.8 1e-51 174.5 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain RPEL PF02755.10 EMC84123.1 - 0.0041 16.3 0.4 0.011 15.0 0.3 1.8 1 0 0 1 1 1 1 RPEL repeat RNA_binding PF01877.12 EMC84123.1 - 0.029 14.3 0.2 0.26 11.3 0.0 2.5 2 1 0 2 2 2 0 RNA binding CLTH PF10607.4 EMC84123.1 - 0.22 11.2 2.2 0.52 9.9 1.5 1.8 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Y_phosphatase PF00102.22 EMC84125.1 - 6e-131 434.8 9.4 5.4e-86 287.7 0.5 2.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EMC84125.1 - 0.00031 20.3 0.1 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC84125.1 - 0.0015 18.7 0.2 0.0059 16.8 0.0 2.1 2 1 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC84125.1 - 0.018 15.0 0.0 0.086 12.8 0.0 2.2 3 0 0 3 3 3 0 Inositol hexakisphosphate FHA PF00498.21 EMC84126.1 - 1.4e-13 50.7 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 FHA domain PP1_bind PF15276.1 EMC84127.1 - 2.9e-26 91.2 2.2 3.8e-26 90.8 1.5 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 binding K167R PF08065.7 EMC84128.1 - 9.9e-16 57.8 7.9 2.7e-07 30.6 0.3 3.6 2 2 1 3 3 3 2 K167R (NUC007) repeat AFP PF02420.10 EMC84129.1 - 0.00046 19.9 11.6 28 5.2 0.0 6.0 6 0 0 6 6 6 0 Insect antifreeze protein repeat FANCAA PF15146.1 EMC84129.1 - 0.00099 18.1 0.2 0.38 9.6 0.0 2.4 1 1 3 4 4 4 3 Fanconi anemia-associated Romo1 PF10247.4 EMC84129.1 - 0.0025 17.9 22.9 1.2 9.4 0.3 5.1 1 1 3 4 4 4 3 Reactive mitochondrial oxygen species modulator 1 Prim_Zn_Ribbon PF08273.7 EMC84129.1 - 0.032 14.3 0.1 45 4.2 0.0 4.3 6 0 0 6 6 6 0 Zinc-binding domain of primase-helicase IFR3_antag PF14754.1 EMC84129.1 - 0.12 11.2 4.1 1 8.3 0.8 2.1 1 1 1 2 2 2 0 Papain-like auto-proteinase GPI2 PF06432.6 EMC84129.1 - 0.14 11.5 0.7 3.9 6.7 0.3 1.9 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1270 PF06900.6 EMC84129.1 - 0.95 9.6 12.1 59 3.9 0.0 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF1270) DUF1675 PF07897.6 EMC84130.1 - 0.48 10.2 15.3 0.035 13.9 7.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) BAMBI PF06211.7 EMC84132.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Pacs-1 PF10254.4 EMC84133.1 - 3.9e-171 569.2 0.5 5.6e-171 568.7 0.3 1.2 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein Cul7 PF11515.3 EMC84134.1 - 4.7e-29 100.1 0.3 8.4e-29 99.3 0.2 1.4 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 DUF1918 PF08940.6 EMC84134.1 - 0.047 13.0 0.2 10 5.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Ribosomal_L2_C PF03947.13 EMC84135.1 - 7e-30 103.4 0.1 1.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMC84135.1 - 1.3e-21 76.3 0.1 3.5e-21 74.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Rab5-bind PF09311.6 EMC84136.1 - 1e-64 217.7 10.7 1e-64 217.7 7.4 3.2 4 0 0 4 4 3 2 Rabaptin-like protein TPR_10 PF13374.1 EMC84136.1 - 2.4e-55 183.0 14.3 4e-11 42.4 0.0 6.7 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMC84136.1 - 3.1e-48 161.5 17.5 3.9e-18 65.1 1.3 5.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMC84136.1 - 8.5e-26 88.4 28.6 1.3e-07 30.8 0.3 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EMC84136.1 - 1.9e-23 80.3 17.2 1.4e-05 24.4 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 EMC84136.1 - 1.2e-22 79.3 18.9 5e-10 38.8 1.6 4.7 3 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 EMC84136.1 - 5.9e-18 63.2 24.5 0.0008 19.1 0.3 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMC84136.1 - 1.9e-17 63.4 3.0 8.9e-06 26.2 0.0 5.0 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC84136.1 - 3.9e-14 52.7 4.7 0.00017 21.8 0.0 4.6 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC84136.1 - 4.9e-12 44.7 18.6 0.084 12.6 0.3 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC84136.1 - 6.7e-12 44.9 5.9 1.1 10.0 0.0 6.7 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC84136.1 - 1.3e-11 43.7 6.9 0.13 12.5 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC84136.1 - 7.8e-10 38.7 13.0 0.00063 19.8 0.0 3.8 2 1 2 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EMC84136.1 - 3e-06 27.1 2.3 1.9 9.1 0.1 6.5 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR PF01535.15 EMC84136.1 - 0.00014 21.6 1.7 0.1 12.6 0.0 4.4 6 0 0 6 6 3 1 PPR repeat SHNi-TPR PF10516.4 EMC84136.1 - 0.0052 15.9 2.4 4.2 6.7 0.0 4.2 4 0 0 4 4 4 1 SHNi-TPR DUF972 PF06156.8 EMC84136.1 - 0.0062 16.8 5.7 0.0062 16.8 4.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF972) DUF3972 PF13118.1 EMC84136.1 - 0.051 13.6 11.3 1.3 9.1 2.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) PPR_3 PF13812.1 EMC84136.1 - 0.13 12.6 0.5 25 5.4 0.0 4.0 5 0 0 5 5 3 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 EMC84136.1 - 0.43 11.1 13.2 1.6 9.3 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.3 EMC84136.1 - 1.7 8.5 19.4 0.027 14.2 6.4 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 EMC84136.1 - 3.3 6.0 8.2 5.4 5.3 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) COG2 PF06148.6 EMC84136.1 - 3.5 7.4 10.7 0.2 11.5 3.3 2.0 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SOUL PF04832.7 EMC84137.1 - 1.2e-36 125.8 0.2 1.4e-36 125.6 0.1 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Exo_endo_phos PF03372.18 EMC84138.1 - 0.1 12.5 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family I-set PF07679.11 EMC84139.1 - 2e-88 290.3 0.0 2.6e-14 52.8 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin I-set domain Pkinase_Tyr PF07714.12 EMC84139.1 - 1.8e-83 279.5 0.0 2.6e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.1 EMC84139.1 - 4.3e-70 231.8 10.8 2.3e-12 46.8 0.1 7.2 7 0 0 7 7 7 7 Immunoglobulin domain Ig_3 PF13927.1 EMC84139.1 - 2.5e-49 165.6 9.3 9.9e-10 38.7 0.3 7.5 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.20 EMC84139.1 - 2.4e-48 162.1 10.9 6.6e-09 35.7 0.1 7.7 7 1 0 7 7 7 7 Immunoglobulin domain Pkinase PF00069.20 EMC84139.1 - 8.8e-44 149.6 0.0 1.4e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.12 EMC84139.1 - 1.2e-30 105.7 5.3 0.00018 21.4 0.1 8.7 7 3 0 7 7 7 6 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC84139.1 - 7.4e-13 48.2 9.6 0.39 10.6 0.0 7.2 7 0 0 7 7 7 4 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC84139.1 - 2.7e-11 42.4 0.5 0.26 9.5 0.0 6.1 2 2 3 6 6 6 4 Alphaherpesvirus glycoprotein E C1-set PF07654.10 EMC84139.1 - 4.1e-06 26.7 1.3 2.2 8.3 0.0 5.8 5 0 0 5 5 5 1 Immunoglobulin C1-set domain C2-set PF05790.10 EMC84139.1 - 6e-06 26.1 0.4 2.2 8.3 0.0 6.1 6 0 0 6 6 6 1 Immunoglobulin C2-set domain Sp38 PF07354.7 EMC84139.1 - 1.6e-05 23.7 0.2 0.34 9.5 0.0 5.0 4 1 1 5 5 5 1 Zona-pellucida-binding protein (Sp38) V-set_CD47 PF08204.6 EMC84139.1 - 2.2e-05 24.2 0.4 0.36 10.6 0.0 4.1 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain CD34_antigen PF06365.7 EMC84139.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SKG6 PF08693.5 EMC84139.1 - 0.042 13.1 0.3 0.093 12.0 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cul7 PF11515.3 EMC84141.1 - 1.7e-21 75.8 0.2 3e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 MOR2-PAG1_N PF14222.1 EMC84141.1 - 0.064 11.9 0.1 0.095 11.3 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal UPF0020 PF01170.13 EMC84142.1 - 1.4e-29 102.9 0.0 2.2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMC84142.1 - 8.8e-16 57.9 0.0 1.5e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC84142.1 - 1.8e-14 53.5 0.0 3.7e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC84142.1 - 8.9e-11 42.1 0.0 2.4e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC84142.1 - 2.9e-09 36.5 0.0 4.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain THUMP PF02926.12 EMC84142.1 - 3.8e-09 36.5 0.0 7.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Ubie_methyltran PF01209.13 EMC84142.1 - 3e-08 33.0 0.0 4.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMC84142.1 - 8.3e-08 32.5 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC84142.1 - 2.7e-07 31.1 0.0 6.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84142.1 - 0.0064 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EMC84142.1 - 0.017 14.1 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 EMC84142.1 - 0.031 13.3 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 EMC84142.1 - 0.069 12.5 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 N6_Mtase PF02384.11 EMC84142.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase MARVEL PF01284.18 EMC84143.1 - 4.7e-06 26.4 6.4 4.7e-06 26.4 4.5 2.2 2 0 0 2 2 2 2 Membrane-associating domain HEV_ORF1 PF02444.11 EMC84143.1 - 0.16 12.1 2.6 0.29 11.3 1.8 1.5 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) DUF485 PF04341.7 EMC84143.1 - 2.5 7.8 8.9 2.6 7.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Ribosomal_S5_C PF03719.10 EMC84144.1 - 1.1e-20 72.6 0.1 2.3e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EMC84144.1 - 1.9e-11 43.5 1.8 5.5e-11 42.0 1.3 1.9 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain YbfN PF13982.1 EMC84144.1 - 0.072 13.2 0.3 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 YbfN-like lipoprotein Sld5 PF05916.6 EMC84145.1 - 0.00021 21.5 0.3 0.0011 19.1 0.0 2.1 2 1 0 2 2 2 1 GINS complex protein ArsR PF09824.4 EMC84146.1 - 0.03 13.6 0.7 0.08 12.2 0.1 1.9 1 1 0 1 1 1 0 ArsR transcriptional regulator CCDC144C PF14915.1 EMC84146.1 - 0.035 13.0 31.0 0.044 12.7 21.5 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region FAM74 PF15026.1 EMC84146.1 - 0.13 11.9 1.5 0.21 11.2 0.7 1.6 1 1 0 1 1 1 0 FAM74 protein DHquinase_II PF01220.14 EMC84146.1 - 0.32 10.3 3.0 0.63 9.3 1.6 1.8 1 1 1 2 2 2 0 Dehydroquinase class II Sec2p PF06428.6 EMC84146.1 - 0.84 9.5 25.9 5.1 6.9 7.6 3.4 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p AAA_13 PF13166.1 EMC84146.1 - 1.8 6.9 21.1 2.1 6.7 14.6 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EMC84146.1 - 2.7 5.7 13.8 3.5 5.3 9.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DEAD_2 PF06733.10 EMC84146.1 - 9.8 5.5 13.3 18 4.7 9.2 1.5 1 1 0 1 1 1 0 DEAD_2 DEAD PF00270.24 EMC84147.1 - 6.7e-35 120.0 0.1 1.8e-34 118.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC84147.1 - 7e-28 96.3 0.0 1.5e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EMC84147.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EMC84147.1 - 0.016 15.3 0.1 0.068 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EMC84147.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EMC84147.1 - 0.034 12.5 0.0 0.31 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Flavi_DEAD PF07652.9 EMC84147.1 - 0.076 12.7 0.2 0.3 10.8 0.0 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain GBP PF02263.14 EMC84148.1 - 2.8e-101 337.9 0.1 3.7e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 EMC84148.1 - 1.5e-06 27.6 0.1 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Dispanin PF04505.7 EMC84149.1 - 2.5e-23 81.4 0.0 4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein MoeA_C PF03454.10 EMC84149.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Cystatin PF00031.16 EMC84150.1 - 4.4e-28 97.2 0.0 5.1e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain Cofilin_ADF PF00241.15 EMC84151.1 - 9.7e-38 128.9 0.3 1.2e-37 128.6 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rib_recp_KP_reg PF05104.7 EMC84152.1 - 1.8e-33 116.1 39.8 1.8e-33 116.1 27.6 4.1 3 1 1 4 4 4 1 Ribosome receptor lysine/proline rich region DUF3899 PF13038.1 EMC84152.1 - 0.22 11.7 5.6 0.1 12.7 0.4 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) OATP PF03137.15 EMC84152.1 - 0.92 7.4 2.8 0.91 7.5 0.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PX PF00787.19 EMC84153.1 - 2e-19 69.4 0.3 2e-19 69.4 0.2 2.7 3 1 0 3 3 3 1 PX domain Vps5 PF09325.5 EMC84153.1 - 7.8e-18 64.5 18.2 1.4e-16 60.5 9.4 2.4 2 1 0 2 2 2 1 Vps5 C terminal like BAR PF03114.13 EMC84153.1 - 1.7e-05 24.4 12.7 0.026 14.0 6.7 2.2 2 0 0 2 2 2 2 BAR domain NusB PF01029.13 EMC84153.1 - 0.078 12.9 4.3 0.076 12.9 1.4 2.0 2 0 0 2 2 2 0 NusB family DUF896 PF05979.7 EMC84153.1 - 0.11 12.1 3.2 1.1 8.9 0.2 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) PDDEXK_1 PF12705.2 EMC84154.1 - 9.9e-09 34.9 0.0 3.8e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily zf-C2H2 PF00096.21 EMC84155.1 - 1.9e-18 65.6 26.1 4.1e-05 23.6 1.8 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC84155.1 - 9.4e-18 63.5 24.4 2.2e-09 37.1 0.4 5.2 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC84155.1 - 6.1e-16 57.5 22.9 3.8e-05 23.7 1.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EMC84155.1 - 0.00017 21.6 16.4 0.0012 18.9 1.5 4.5 3 1 2 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC84155.1 - 0.00025 21.0 18.6 0.12 12.5 0.4 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMC84155.1 - 0.012 15.7 12.5 0.062 13.4 2.5 3.6 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.16 EMC84155.1 - 0.02 14.8 19.5 14 5.6 13.5 2.6 1 1 0 1 1 1 0 FYVE zinc finger XPA_N PF01286.13 EMC84155.1 - 0.054 13.1 10.9 3.3 7.4 0.0 4.3 4 0 0 4 4 4 0 XPA protein N-terminal C1_3 PF07649.7 EMC84155.1 - 0.48 10.5 11.0 2.9 8.0 0.1 4.1 4 0 0 4 4 4 0 C1-like domain C1_1 PF00130.17 EMC84155.1 - 0.53 10.0 16.4 0.78 9.5 4.9 3.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 EMC84155.1 - 0.61 9.6 0.1 0.61 9.6 0.1 3.6 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-C2H2_2 PF12756.2 EMC84155.1 - 0.64 10.1 16.0 1.7 8.8 0.7 3.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.9 EMC84155.1 - 1.9 8.1 10.8 3.4 7.4 1.8 4.1 3 1 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 EMC84155.1 - 4.4 7.3 17.2 6.6 6.7 0.5 4.5 3 1 1 4 4 4 0 Zinc ribbon domain Acetyltransf_1 PF00583.19 EMC84156.1 - 1.5e-10 40.9 0.0 5.4e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC84156.1 - 1.4e-09 37.9 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC84156.1 - 1.9e-09 37.6 0.0 3.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC84156.1 - 6.3e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EMC84156.1 - 0.001 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BIR PF00653.16 EMC84157.1 - 3.3e-21 75.4 1.0 4.5e-21 75.0 0.7 1.2 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain CHB_HEX_C_1 PF13290.1 EMC84158.1 - 4.7e-16 58.3 0.1 9.1e-16 57.3 0.1 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain DZR PF12773.2 EMC84158.1 - 2.6e-15 55.9 39.2 1.3e-07 31.3 12.0 3.5 2 1 1 3 3 3 3 Double zinc ribbon Fn3_assoc PF13287.1 EMC84158.1 - 8e-15 54.6 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C PF03174.8 EMC84158.1 - 3.2e-14 52.5 0.0 6.7e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain zf-ribbon_3 PF13248.1 EMC84158.1 - 1.2e-08 33.8 31.5 0.00094 18.3 3.0 4.8 4 0 0 4 4 4 4 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMC84158.1 - 0.00073 18.9 4.2 0.00073 18.9 2.9 5.1 5 0 0 5 5 5 3 zinc-ribbon domain zf-RanBP PF00641.13 EMC84158.1 - 0.01 14.9 1.1 0.01 14.9 0.7 5.5 5 0 0 5 5 5 0 Zn-finger in Ran binding protein and others Mut7-C PF01927.11 EMC84158.1 - 0.75 9.7 6.6 0.72 9.8 1.6 2.6 2 0 0 2 2 2 0 Mut7-C RNAse domain RNA_pol_Rpc34 PF05158.7 EMC84159.1 - 1.6e-105 352.8 0.7 1.8e-105 352.7 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 EMC84159.1 - 4.1e-05 23.2 0.8 0.0044 16.7 0.1 3.1 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.6 EMC84159.1 - 0.0042 17.4 2.6 0.39 11.1 0.0 3.4 4 0 0 4 4 4 1 Replication protein A C terminal HTH_24 PF13412.1 EMC84159.1 - 0.019 14.3 0.4 0.064 12.6 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TFIIE_alpha PF02002.12 EMC84159.1 - 0.031 13.7 0.4 0.075 12.5 0.2 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit B-block_TFIIIC PF04182.7 EMC84159.1 - 0.035 13.9 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_45 PF14947.1 EMC84159.1 - 0.1 12.4 2.4 0.13 12.0 0.5 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix SCPU PF05229.10 EMC84159.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 1 0 1 1 1 0 Spore Coat Protein U domain Tyr_Deacylase PF02580.11 EMC84160.1 - 7.6e-48 162.1 0.0 9.2e-48 161.9 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Toprim_C_rpt PF13368.1 EMC84160.1 - 0.029 14.8 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat DUF3432 PF11914.3 EMC84161.1 - 0.00014 21.8 75.8 8.4 6.4 4.3 8.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3432) DUF3432 PF11914.3 EMC84162.1 - 0.00044 20.2 104.1 1.5e+04 -81.6 72.1 10.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Collagen PF01391.13 EMC84163.1 - 0.00076 18.9 15.9 0.024 14.1 10.7 2.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) KLRAQ PF10205.4 EMC84164.1 - 4e-36 123.1 16.2 4e-36 123.1 11.2 2.6 3 0 0 3 3 3 1 Predicted coiled-coil domain-containing protein DUF1455 PF07306.6 EMC84164.1 - 0.075 13.1 0.8 1.1 9.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) CENP-Q PF13094.1 EMC84164.1 - 0.44 10.5 24.1 0.25 11.3 15.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.2 EMC84164.1 - 0.61 9.9 28.0 0.89 9.3 17.6 2.2 1 1 1 2 2 2 0 Tropomyosin like DUF641 PF04859.7 EMC84164.1 - 5.1 6.8 17.6 0.18 11.5 3.9 3.0 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Fork_head PF00250.13 EMC84165.1 - 0.064 13.2 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Fork head domain MbeB_N PF04837.7 EMC84165.1 - 0.1 12.6 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Beta_helix PF13229.1 EMC84166.1 - 4.7e-69 231.1 65.7 4.4e-24 85.0 10.4 4.6 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.8 EMC84166.1 - 7.5e-45 152.9 51.4 1.9e-17 63.2 5.2 4.8 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) F-box-like PF12937.2 EMC84166.1 - 2.7e-16 59.0 0.3 5.7e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like zf-UBR PF02207.15 EMC84166.1 - 3.9e-12 45.7 12.7 3.9e-12 45.7 8.8 1.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.28 EMC84166.1 - 7e-08 31.9 0.3 7e-08 31.9 0.2 1.8 2 0 0 2 2 2 1 F-box domain MutS_V PF00488.16 EMC84167.1 - 1.1e-83 280.3 0.0 1.6e-83 279.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC84167.1 - 2.4e-46 158.1 0.0 3.8e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMC84167.1 - 2.1e-33 114.7 0.0 5.5e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I PWWP PF00855.12 EMC84167.1 - 2.3e-21 75.7 2.4 3.4e-21 75.2 0.0 2.6 3 0 0 3 3 3 1 PWWP domain MutS_IV PF05190.13 EMC84167.1 - 1.7e-17 63.3 0.2 7e-17 61.3 0.1 2.2 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EMC84167.1 - 1.3e-13 51.2 0.3 8.1e-13 48.6 0.2 2.3 1 1 0 1 1 1 1 MutS domain II Plasmid_RAQPRD PF09686.5 EMC84167.1 - 0.13 12.3 0.6 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Ion_trans_2 PF07885.11 EMC84168.1 - 1.1e-31 108.3 21.7 5.8e-16 57.9 6.3 2.2 2 0 0 2 2 2 2 Ion channel Presenilin PF01080.12 EMC84168.1 - 0.14 10.9 3.4 0.19 10.4 2.4 1.2 1 0 0 1 1 1 0 Presenilin MutS_V PF00488.16 EMC84169.1 - 9.7e-101 336.0 0.1 1.6e-100 335.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMC84169.1 - 7e-38 130.4 2.0 7e-38 130.4 1.4 2.0 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.12 EMC84169.1 - 4e-22 78.7 0.2 1.3e-21 77.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EMC84169.1 - 1.3e-19 70.1 3.1 3.5e-19 68.7 2.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EMC84169.1 - 3.2e-05 23.9 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain I DUF2935 PF11155.3 EMC84169.1 - 7.2 6.7 11.9 9 6.4 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF2935) Thyroglobulin_1 PF00086.13 EMC84170.1 - 2.3e-14 52.4 2.7 3.9e-14 51.7 1.9 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF4381 PF14316.1 EMC84170.1 - 0.002 18.2 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DAG1 PF05454.6 EMC84170.1 - 0.02 14.0 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF1947 PF09183.5 EMC84170.1 - 0.021 14.5 0.2 0.054 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Rifin_STEVOR PF02009.11 EMC84170.1 - 0.039 13.6 5.5 0.042 13.4 3.8 1.2 1 1 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EMC84170.1 - 0.05 14.0 0.9 0.18 12.2 0.6 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.14 EMC84170.1 - 0.22 11.0 1.8 0.37 10.3 0.5 1.8 2 0 0 2 2 2 0 Vpu protein Peptidase_S49_N PF08496.5 EMC84170.1 - 0.25 11.1 1.9 0.33 10.7 0.5 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spy1 PF11357.3 EMC84171.1 - 3.3e-65 218.0 4.9 4.3e-65 217.6 3.4 1.1 1 0 0 1 1 1 1 Cell cycle regulatory protein GCD14 PF08704.5 EMC84172.1 - 2.8e-21 76.1 0.0 3.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EMC84172.1 - 3.4e-10 39.6 0.0 8.1e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC84172.1 - 8e-10 38.6 0.0 9.6e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EMC84172.1 - 9.8e-09 35.2 0.1 4.8e-08 33.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC84172.1 - 2.1e-08 34.6 0.0 2.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EMC84172.1 - 1.5e-05 25.7 0.0 2.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC84172.1 - 4.8e-05 23.6 0.0 6.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC84172.1 - 0.00023 21.2 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EMC84172.1 - 0.00029 21.2 0.0 0.00057 20.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EMC84172.1 - 0.00032 20.0 0.0 0.00079 18.7 0.0 1.5 2 0 0 2 2 2 1 Cephalosporin hydroxylase RrnaAD PF00398.15 EMC84172.1 - 0.00068 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EMC84172.1 - 0.0033 17.1 0.0 0.0049 16.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC84172.1 - 0.006 15.9 0.0 0.013 14.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMC84172.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 EMC84172.1 - 0.026 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 EMC84172.1 - 0.03 13.3 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EMC84172.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2704 PF10866.3 EMC84172.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) 7tm_1 PF00001.16 EMC84173.1 - 9.8e-14 51.1 7.5 1.1e-13 50.9 5.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC84173.1 - 0.0037 16.4 4.0 0.0037 16.4 2.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-A20 PF01754.11 EMC84175.1 - 0.007 15.9 13.7 53 3.5 0.0 6.0 6 0 0 6 6 6 6 A20-like zinc finger LELP1 PF15042.1 EMC84175.1 - 0.087 13.0 58.0 5.1 7.3 14.4 3.9 1 1 2 3 3 3 0 Late cornified envelope-like proline-rich protein 1 MSG PF02349.10 EMC84176.1 - 0.00059 19.7 11.0 0.038 13.9 0.5 2.9 1 1 2 3 3 3 3 Major surface glycoprotein IGFBP PF00219.13 EMC84176.1 - 2.3 8.8 36.9 21 5.7 0.9 4.9 2 1 0 2 2 2 0 Insulin-like growth factor binding protein IL7 PF01415.11 EMC84177.1 - 0.00049 19.7 6.6 0.0006 19.4 4.6 1.1 1 0 0 1 1 1 1 Interleukin 7/9 family DUF1448 PF07289.6 EMC84177.1 - 0.0082 15.1 0.3 0.01 14.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) zf-C2HC_2 PF13913.1 EMC84178.1 - 7.2e-15 54.2 6.9 7.9e-09 34.9 0.5 2.7 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 EMC84178.1 - 0.0075 15.4 4.0 0.0075 15.4 2.8 3.0 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMC84178.1 - 0.02 14.3 5.8 0.02 14.3 4.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Nairovirus_M PF07948.6 EMC84178.1 - 0.031 12.4 0.2 0.047 11.8 0.1 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DUF2321 PF10083.4 EMC84178.1 - 0.12 11.8 0.4 0.42 10.0 0.3 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Rod_cone_degen PF15201.1 EMC84178.1 - 0.15 11.9 1.7 0.46 10.3 1.2 1.8 1 0 0 1 1 1 0 Progressive rod-cone degeneration HypA PF01155.14 EMC84178.1 - 0.17 11.6 8.8 2.4 7.8 1.2 3.1 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EMC84178.1 - 0.27 11.0 15.9 0.06 13.1 1.6 3.4 3 1 0 3 3 3 0 Double zinc ribbon zf-C2H2 PF00096.21 EMC84178.1 - 0.67 10.4 0.1 0.67 10.4 0.0 4.3 5 0 0 5 5 3 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.1 EMC84178.1 - 0.85 9.3 6.3 12 5.7 0.5 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMC84178.1 - 0.88 9.2 5.8 9.6 5.8 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EMC84178.1 - 3.5 7.6 8.7 5.5 7.0 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger PKI PF02827.11 EMC84179.1 - 6.6e-35 119.0 1.4 7.3e-35 118.9 1.0 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Pex2_Pex12 PF04757.9 EMC84180.1 - 2e-36 125.5 4.4 2.9e-36 125.0 3.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 EMC84180.1 - 2.6e-08 33.3 8.7 2.6e-08 33.3 6.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC84180.1 - 0.00052 19.8 10.9 0.0014 18.4 7.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMC84180.1 - 0.00096 19.1 10.0 0.00096 19.1 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC84180.1 - 0.0011 18.7 8.4 0.0011 18.7 5.8 2.0 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 EMC84180.1 - 0.0092 15.6 14.0 0.013 15.2 7.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC84180.1 - 0.023 14.3 8.3 0.043 13.4 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RDD PF06271.7 EMC84180.1 - 0.094 12.6 2.3 0.22 11.3 0.7 1.9 1 1 1 2 2 2 0 RDD family zf-RING_6 PF14835.1 EMC84180.1 - 0.31 10.8 4.2 0.87 9.4 2.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EMC84180.1 - 0.51 10.4 6.6 1 9.4 4.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger HypA PF01155.14 EMC84180.1 - 3.7 7.2 5.5 25 4.6 3.1 2.7 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Hormone_recep PF00104.25 EMC84181.1 - 2.6e-39 134.4 0.1 4.1e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC84181.1 - 2.2e-24 85.4 12.5 4.2e-24 84.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 EMC84181.1 - 0.049 11.1 0.7 0.065 10.7 0.5 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein LCCL PF03815.14 EMC84182.1 - 2.2e-51 171.8 16.4 1.3e-26 92.3 0.4 3.2 3 0 0 3 3 3 2 LCCL domain CAP PF00188.21 EMC84182.1 - 1.4e-19 70.8 1.2 3.2e-19 69.6 0.8 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.5 EMC84182.1 - 0.014 15.6 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 CAP PF00188.21 EMC84183.1 - 5e-22 78.7 2.1 7.7e-22 78.0 1.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GST_N_3 PF13417.1 EMC84184.1 - 4.1e-12 46.1 0.0 8.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC84184.1 - 9.8e-10 38.4 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC84184.1 - 1.1e-09 37.9 0.0 2.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC84184.1 - 1.5e-08 34.4 0.0 3.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC84184.1 - 4e-08 33.1 0.1 2.2e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC84184.1 - 0.00013 22.4 0.1 0.00027 21.3 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1617 PF07761.7 EMC84184.1 - 0.029 14.4 1.2 0.054 13.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) DUF2096 PF09869.4 EMC84184.1 - 0.032 14.1 1.7 0.3 10.9 0.3 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) DUF3206 PF11472.3 EMC84184.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Med30 PF11315.3 EMC84184.1 - 0.04 14.0 2.6 0.2 11.7 1.8 2.0 1 1 0 1 1 1 0 Mediator complex subunit 30 MtrG PF04210.8 EMC84184.1 - 0.1 12.2 0.6 0.26 10.9 0.4 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G MCR_C PF04609.7 EMC84184.1 - 0.13 11.0 0.2 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C CCDC-167 PF15188.1 EMC84184.1 - 9.2 6.2 8.1 18 5.3 0.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 MORN PF02493.15 EMC84185.1 - 1.3e-17 62.3 17.2 2.9e-07 29.8 0.6 3.8 3 0 0 3 3 3 3 MORN repeat DUF1301 PF06979.7 EMC84186.1 - 4.3e-65 217.8 8.0 5.3e-65 217.5 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1301) Skp1_POZ PF03931.10 EMC84187.1 - 1.7e-23 82.5 0.0 2.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain UQ_con PF00179.21 EMC84188.1 - 3.7e-34 117.1 0.2 4e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC84188.1 - 2.8e-05 23.8 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EMC84188.1 - 0.0078 15.8 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EMC84188.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain dsrm PF00035.20 EMC84189.1 - 4.4e-52 174.5 2.2 1.1e-13 51.5 0.0 4.6 4 0 0 4 4 4 4 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EMC84189.1 - 4.8e-10 39.5 4.4 0.0021 18.3 0.0 5.0 4 2 0 4 4 4 3 double strand RNA binding domain from DEAD END PROTEIN 1 TMEM169 PF15052.1 EMC84190.1 - 7.1e-71 236.3 8.1 9.1e-71 236.0 5.6 1.1 1 0 0 1 1 1 1 TMEM169 protein family THRAP3_BCLAF1 PF15440.1 EMC84190.1 - 0.075 11.6 5.2 0.093 11.3 3.6 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family 60KD_IMP PF02096.15 EMC84190.1 - 0.076 12.6 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Ku_N PF03731.10 EMC84191.1 - 4.7e-61 206.0 1.1 4.7e-61 206.0 0.7 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EMC84191.1 - 8.2e-46 154.7 3.5 2.8e-44 149.8 1.2 2.8 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.11 EMC84191.1 - 3.5e-44 150.6 1.2 6.1e-44 149.8 0.8 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EMC84191.1 - 1e-27 96.4 4.8 2.4e-27 95.3 2.2 2.6 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 EMC84191.1 - 2.7e-06 27.5 0.0 5.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMC84191.1 - 0.0013 18.5 0.1 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain HARP PF07443.8 EMC84192.1 - 1.3e-50 168.5 0.5 6.2e-25 86.3 0.0 2.4 2 0 0 2 2 2 2 HepA-related protein (HARP) SNF2_N PF00176.18 EMC84192.1 - 3.3e-29 101.6 0.0 5.5e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC84192.1 - 1.8e-12 46.9 0.0 5e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC84192.1 - 0.00058 19.3 0.2 0.038 13.4 0.0 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase TK PF00265.13 EMC84192.1 - 0.029 13.9 0.0 0.085 12.4 0.0 1.8 1 0 0 1 1 1 0 Thymidine kinase Flavi_DEAD PF07652.9 EMC84192.1 - 0.058 13.1 0.1 0.77 9.5 0.0 2.5 2 1 0 2 2 2 0 Flavivirus DEAD domain Ribosomal_L37ae PF01780.14 EMC84193.1 - 1.7e-39 133.5 9.5 1.9e-39 133.4 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-C4_ClpX PF06689.8 EMC84193.1 - 0.018 14.5 0.3 0.018 14.5 0.2 1.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger Rsm1 PF08600.5 EMC84193.1 - 0.02 14.7 0.6 0.028 14.2 0.4 1.3 1 0 0 1 1 1 0 Rsm1-like zf-DHHC PF01529.15 EMC84193.1 - 0.024 14.0 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Elf1 PF05129.8 EMC84193.1 - 0.027 14.1 0.3 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 EMC84193.1 - 0.032 13.8 0.8 0.045 13.4 0.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 EMC84193.1 - 0.055 12.9 2.7 0.088 12.2 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EMC84193.1 - 0.067 13.0 1.8 0.1 12.3 1.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMC84193.1 - 0.21 11.5 1.3 0.33 10.9 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Rep_fac-A_C PF08646.5 EMC84193.1 - 0.22 11.2 2.3 0.32 10.6 1.6 1.4 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-BED PF02892.10 EMC84193.1 - 0.39 10.5 5.7 1.6 8.5 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.10 EMC84193.1 - 2.4 7.7 6.1 0.65 9.6 1.0 2.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Thyroglobulin_1 PF00086.13 EMC84194.1 - 3.8e-21 74.2 1.0 7.3e-21 73.2 0.7 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF3984 PF13136.1 EMC84194.1 - 0.031 13.5 0.1 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Nitr_red_bet_C PF14711.1 EMC84194.1 - 0.19 11.2 0.9 2.5 7.6 0.2 2.3 1 1 1 2 2 2 0 Respiratory nitrate reductase beta C-terminal Thyroglobulin_1 PF00086.13 EMC84195.1 - 4.5e-08 32.3 1.4 5.8e-08 31.9 0.2 1.8 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat ScpA_ScpB PF02616.9 EMC84195.1 - 0.15 11.6 0.4 0.15 11.6 0.3 1.1 1 0 0 1 1 1 0 ScpA/B protein SH2 PF00017.19 EMC84196.1 - 3.5e-09 36.3 0.0 6.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 SH2 domain RUN PF02759.14 EMC84197.1 - 2.4e-11 43.5 0.2 2.7e-11 43.3 0.1 1.0 1 0 0 1 1 1 1 RUN domain IKKbetaNEMObind PF12179.3 EMC84197.1 - 0.031 14.1 1.3 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain 7tm_1 PF00001.16 EMC84198.1 - 9.3e-62 208.4 14.5 9.3e-62 208.4 10.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC84198.1 - 2.9e-08 33.2 12.8 4.1e-08 32.7 8.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC84198.1 - 0.002 17.9 4.9 0.002 17.9 3.4 2.9 1 1 2 3 3 3 1 Olfactory receptor ABC2_membrane_5 PF13346.1 EMC84198.1 - 0.032 13.5 13.7 0.21 10.8 4.5 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein SP_C-Propep PF08999.5 EMC84198.1 - 0.12 11.8 2.5 0.11 11.9 0.3 1.9 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide WD40 PF00400.27 EMC84199.1 - 1.4e-38 129.3 12.9 1.5e-07 31.0 0.3 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EMC84199.1 - 1e-07 31.8 0.3 0.0065 16.2 0.1 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC84199.1 - 5e-05 21.6 0.2 0.14 10.2 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC84199.1 - 0.0016 17.2 0.0 0.082 11.6 0.0 2.5 3 0 0 3 3 3 1 Nup133 N terminal like PQQ PF01011.16 EMC84199.1 - 0.0089 15.5 3.3 0.9 9.1 0.0 4.1 4 0 0 4 4 4 1 PQQ enzyme repeat Apc4_WD40 PF12894.2 EMC84199.1 - 0.066 12.7 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Bax1-I PF01027.15 EMC84201.1 - 8.9e-25 87.4 26.0 3.2e-24 85.6 18.0 1.7 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Claudin_2 PF13903.1 EMC84201.1 - 0.017 14.8 0.8 0.017 14.8 0.5 2.5 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4231 PF14015.1 EMC84201.1 - 5.6 6.9 9.9 1.3e+02 2.6 6.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Lactamase_B PF00753.22 EMC84202.1 - 2e-15 56.9 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC84202.1 - 0.00015 21.4 0.0 0.00027 20.5 0.0 1.4 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Nramp PF01566.13 EMC84204.1 - 6.5e-112 373.8 13.9 6.5e-112 373.8 9.6 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein NIF PF03031.13 EMC84205.1 - 7.7e-52 175.1 0.0 9.3e-52 174.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.3 EMC84205.1 - 0.061 12.3 0.0 0.98 8.3 0.1 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2608) Gelsolin PF00626.17 EMC84206.1 - 5.6e-107 349.5 0.0 8.4e-19 67.0 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.14 EMC84206.1 - 7.2e-15 54.3 0.8 1.5e-14 53.3 0.6 1.6 1 0 0 1 1 1 1 Villin headpiece domain UCH PF00443.24 EMC84207.1 - 4.9e-67 225.8 1.7 7.3e-67 225.3 1.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC84207.1 - 9.7e-20 71.1 18.3 2.8e-16 59.8 2.3 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.15 EMC84207.1 - 3.3e-07 29.3 22.5 0.0012 18.1 0.2 4.0 3 0 0 3 3 3 3 Ubiquitin interaction motif Elongin_A PF06881.6 EMC84207.1 - 0.15 12.4 6.4 0.58 10.5 4.5 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Rcd1 PF04078.8 EMC84208.1 - 1.4e-134 446.9 0.3 1.6e-134 446.7 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like BCS1_N PF08740.6 EMC84209.1 - 2.7e-49 167.3 2.0 7.4e-49 165.9 1.4 1.7 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMC84209.1 - 1.7e-20 73.5 0.0 3.6e-20 72.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC84209.1 - 0.00026 21.7 0.0 0.00064 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMC84209.1 - 0.00073 19.6 0.0 0.0021 18.2 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EMC84209.1 - 0.0008 19.4 0.1 0.0026 17.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EMC84209.1 - 0.00082 18.3 0.0 0.0019 17.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMC84209.1 - 0.0056 16.4 0.0 0.027 14.2 0.0 2.2 3 0 0 3 3 1 1 Part of AAA domain AAA_33 PF13671.1 EMC84209.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC84209.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 EMC84209.1 - 0.018 13.7 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EMC84209.1 - 0.019 15.1 0.0 0.16 12.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 EMC84209.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMC84209.1 - 0.023 14.1 0.2 0.094 12.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain RuvB_N PF05496.7 EMC84209.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMC84209.1 - 0.029 14.0 0.0 0.11 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EMC84209.1 - 0.034 13.7 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMC84209.1 - 0.038 13.6 0.0 0.092 12.4 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EMC84209.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EMC84209.1 - 0.086 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 EMC84209.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC84209.1 - 0.13 11.8 0.1 0.38 10.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.1 EMC84210.1 - 1.9e-13 49.9 5.1 3.5e-13 49.1 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain RWD PF05773.17 EMC84210.1 - 5.4e-13 48.8 0.0 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.1 EMC84210.1 - 5e-05 22.9 6.7 0.00012 21.7 4.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC84210.1 - 0.00042 20.2 4.0 0.0018 18.2 2.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC84210.1 - 0.0073 15.9 5.1 0.072 12.7 3.8 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC84210.1 - 0.013 15.1 3.4 0.035 13.7 2.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC84210.1 - 0.017 15.2 6.7 0.21 11.6 4.5 2.4 1 1 1 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC84210.1 - 0.18 11.6 4.7 0.31 10.9 1.2 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TTL PF03133.10 EMC84211.1 - 5.6e-101 337.3 0.1 8.9e-101 336.6 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMC84211.1 - 1.7e-05 23.7 0.3 0.00041 19.2 0.0 3.0 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EMC84211.1 - 0.013 15.2 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC84211.1 - 0.02 13.6 0.0 2.3 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EMC84211.1 - 0.15 11.9 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain CBS PF00571.23 EMC84212.1 - 1e-40 137.2 5.1 2.2e-12 46.5 0.1 4.3 4 0 0 4 4 4 4 CBS domain p450 PF00067.17 EMC84213.1 - 2.9e-100 335.9 0.0 3.6e-100 335.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 wnt PF00110.14 EMC84214.1 - 1.5e-116 388.9 17.0 1.8e-116 388.6 11.8 1.1 1 0 0 1 1 1 1 wnt family Clr5 PF14420.1 EMC84214.1 - 0.14 12.0 0.2 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Clr5 domain wnt PF00110.14 EMC84215.1 - 1.4e-121 405.5 18.8 1.5e-121 405.3 13.1 1.0 1 0 0 1 1 1 1 wnt family CDK5_activator PF03261.10 EMC84216.1 - 3.6e-46 158.0 0.0 4.6e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein Ets PF00178.17 EMC84217.1 - 8.5e-40 134.7 0.9 1.2e-39 134.2 0.6 1.2 1 0 0 1 1 1 1 Ets-domain Crystall PF00030.14 EMC84218.1 - 1.7e-37 127.1 6.3 2e-27 94.8 0.3 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin Homeobox PF00046.24 EMC84219.1 - 1.2e-22 79.2 7.1 1.7e-22 78.7 4.9 1.3 1 0 0 1 1 1 1 Homeobox domain QLQ PF08880.6 EMC84219.1 - 0.0027 17.0 0.2 0.005 16.2 0.2 1.4 1 0 0 1 1 1 1 QLQ Hint PF01079.15 EMC84220.1 - 4.2e-72 241.8 0.0 5.3e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Hint module HH_signal PF01085.13 EMC84220.1 - 4.1e-55 185.7 0.6 5.6e-55 185.2 0.4 1.2 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.6 EMC84220.1 - 0.00098 18.9 0.1 0.0015 18.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase M15 XLF PF09302.6 EMC84221.1 - 5.6e-31 107.6 0.0 1e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Xan_ur_permease PF00860.15 EMC84222.1 - 1.9e-67 227.4 16.8 3.2e-67 226.7 11.7 1.4 1 1 0 1 1 1 1 Permease family Bap31 PF05529.7 EMC84222.1 - 0.19 11.1 0.1 0.36 10.2 0.1 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zf-AN1 PF01428.11 EMC84224.1 - 2.7e-20 71.9 23.3 4.8e-12 45.5 6.0 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger UIM PF02809.15 EMC84224.1 - 0.0003 20.1 19.1 0.00085 18.6 4.1 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif Transp_Tc5_C PF04236.10 EMC84224.1 - 0.078 13.2 14.7 1.2 9.3 1.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C3HC PF07967.8 EMC84224.1 - 9.6 5.9 9.8 2.1 8.1 0.9 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like ABC_tran PF00005.22 EMC84225.1 - 1.3e-34 119.4 0.0 2.2e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMC84225.1 - 7.8e-29 100.9 12.2 1.2e-28 100.3 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EMC84225.1 - 2e-06 27.2 0.1 9e-05 21.8 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC84225.1 - 2.2e-05 24.5 0.7 0.0011 18.9 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMC84225.1 - 4.3e-05 23.5 0.3 9.8e-05 22.4 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EMC84225.1 - 0.00024 20.3 0.0 0.00048 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC84225.1 - 0.00051 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMC84225.1 - 0.0015 18.7 0.1 0.014 15.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EMC84225.1 - 0.0017 18.5 0.1 0.034 14.3 0.0 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC84225.1 - 0.0028 18.4 0.0 0.006 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMC84225.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EMC84225.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMC84225.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EMC84225.1 - 0.021 14.7 0.3 0.23 11.3 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EMC84225.1 - 0.027 14.1 0.2 0.42 10.3 0.1 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Acyl-CoA_dh_1 PF00441.19 EMC84225.1 - 0.043 13.9 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain MobB PF03205.9 EMC84225.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EMC84225.1 - 0.063 13.1 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EMC84225.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EMC84225.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMC84225.1 - 0.18 11.3 0.1 0.6 9.5 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APG9 PF04109.11 EMC84227.1 - 3.5e-135 450.6 1.2 4.7e-135 450.2 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 EMP24_GP25L PF01105.19 EMC84227.1 - 0.069 12.8 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Glyco_hydro_35 PF01301.14 EMC84228.1 - 1.6e-94 316.8 0.0 3.6e-94 315.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 EMC84228.1 - 2e-11 43.6 0.0 2.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 EMC84228.1 - 1.1e-08 35.2 0.0 6.8e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Pkinase PF00069.20 EMC84229.1 - 9.9e-42 142.8 0.0 1.2e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84229.1 - 6.1e-26 91.0 0.0 7.5e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC84229.1 - 7.3e-06 25.1 0.1 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC84229.1 - 7.3e-05 22.6 0.4 0.061 13.0 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC84229.1 - 0.00013 21.0 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Tubulin PF00091.20 EMC84230.1 - 3.9e-69 232.7 0.0 5.1e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC84230.1 - 1e-51 174.2 0.0 1.7e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC84230.1 - 0.0009 18.7 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4253 PF14062.1 EMC84230.1 - 0.061 12.9 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Tubulin PF00091.20 EMC84231.1 - 1.7e-67 227.4 0.0 2.2e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC84231.1 - 1.4e-51 173.7 0.0 3e-51 172.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC84231.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4253 PF14062.1 EMC84231.1 - 0.065 12.8 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Peptidase_M18 PF02127.10 EMC84232.1 - 1.1e-152 508.4 0.0 1.3e-152 508.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EMC84232.1 - 4.2e-08 32.3 0.0 1.2e-05 24.3 0.0 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Filament PF00038.16 EMC84233.1 - 5e-53 180.5 25.2 5.9e-53 180.3 17.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.9 EMC84233.1 - 2.9e-23 82.3 8.8 4.6e-23 81.7 6.1 1.3 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region HR1 PF02185.11 EMC84233.1 - 0.0025 17.5 13.0 0.0025 17.5 9.0 3.8 2 2 1 3 3 3 1 Hr1 repeat Myosin_tail_1 PF01576.14 EMC84233.1 - 0.01 13.5 27.9 0.057 11.1 10.0 2.1 1 1 1 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 EMC84233.1 - 0.022 13.9 0.2 0.033 13.3 0.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF812 PF05667.6 EMC84233.1 - 0.17 10.3 16.5 0.46 8.9 10.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 EMC84233.1 - 0.2 11.3 23.2 2 8.1 10.2 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 EMC84233.1 - 0.42 10.4 23.8 18 5.1 15.6 2.6 1 1 0 1 1 1 0 Tropomyosin like AAA_13 PF13166.1 EMC84233.1 - 0.46 8.8 10.7 0.76 8.1 7.4 1.3 1 0 0 1 1 1 0 AAA domain KLRAQ PF10205.4 EMC84233.1 - 0.53 10.3 15.3 0.056 13.4 6.8 2.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein FlxA PF14282.1 EMC84233.1 - 0.55 10.1 15.8 0.3 11.0 1.1 3.1 3 0 0 3 3 3 0 FlxA-like protein DUF4559 PF15112.1 EMC84233.1 - 0.62 9.1 11.9 0.86 8.6 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF948 PF06103.6 EMC84233.1 - 0.85 9.5 4.1 0.46 10.3 0.3 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.16 EMC84233.1 - 1.3 9.0 14.0 0.47 10.4 0.8 3.6 3 1 0 3 3 3 0 bZIP transcription factor HALZ PF02183.13 EMC84233.1 - 2.1 8.1 18.7 0.52 10.0 3.2 3.9 3 1 0 3 3 3 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 EMC84233.1 - 3.3 7.5 8.9 1.4 8.7 3.2 2.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Band_7 PF01145.20 EMC84233.1 - 4.4 7.1 10.5 6.6 6.5 7.3 1.4 1 0 0 1 1 1 0 SPFH domain / Band 7 family TBPIP PF07106.8 EMC84233.1 - 6 6.3 20.2 22 4.5 0.4 3.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EMC84233.1 - 6.4 5.3 17.1 9.6 4.7 11.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF947 PF06102.7 EMC84233.1 - 7.5 6.3 13.9 4.6 7.0 2.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF947) ACCA PF03255.9 EMC84233.1 - 9.3 5.7 13.9 6.2 6.3 1.5 2.8 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit NTP_transferase PF00483.18 EMC84236.1 - 1.2e-15 57.4 0.0 1.9e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EMC84236.1 - 0.019 14.4 14.1 0.19 11.3 0.5 5.0 3 1 2 5 5 5 0 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMC84236.1 - 1.2 8.7 5.4 0.27 10.8 0.5 2.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase RhoGAP PF00620.22 EMC84237.1 - 3.2e-38 130.7 0.0 4.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 EMC84237.1 - 5.5e-06 26.0 4.4 1.1e-05 25.0 3.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMC84237.1 - 0.062 13.0 5.5 0.15 11.8 3.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EMC84237.1 - 0.36 10.5 4.4 0.74 9.5 3.0 1.5 1 0 0 1 1 1 0 PHD-finger Rootletin PF15035.1 EMC84238.1 - 0.014 15.3 8.6 0.019 14.9 5.9 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.1 EMC84238.1 - 0.017 14.3 2.8 0.024 13.8 1.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.3 EMC84238.1 - 0.88 8.9 6.8 1.3 8.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ASC PF00858.19 EMC84239.1 - 4.6e-39 134.2 0.0 5.1e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.19 EMC84240.1 - 1.1e-156 521.8 0.0 1.3e-156 521.6 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel I-set PF07679.11 EMC84241.1 - 1.6e-104 341.9 0.0 2.7e-17 62.3 0.0 13.3 12 1 0 12 12 12 12 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84241.1 - 4.4e-73 241.4 0.0 1.2e-09 38.1 0.0 11.1 8 2 3 11 11 11 9 Immunoglobulin domain V-set PF07686.12 EMC84241.1 - 2.8e-41 139.9 2.3 0.0028 17.5 0.0 15.5 11 4 2 13 13 13 8 Immunoglobulin V-set domain ig PF00047.20 EMC84241.1 - 3.8e-38 129.4 0.0 0.0015 18.5 0.0 11.4 11 0 0 11 11 11 8 Immunoglobulin domain Ig_3 PF13927.1 EMC84241.1 - 1.8e-22 79.5 0.0 0.37 11.3 0.0 11.6 12 0 0 12 12 12 5 Immunoglobulin domain C2-set_2 PF08205.7 EMC84241.1 - 4e-12 45.8 3.4 0.00082 19.2 0.0 6.9 7 0 0 7 7 7 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC84241.1 - 1.5e-11 44.1 3.5 0.15 12.1 0.0 7.7 7 0 0 7 7 7 2 Immunoglobulin C1-set domain BiPBP_C PF06832.7 EMC84241.1 - 7.8e-10 38.5 0.8 4 7.4 0.0 7.9 7 1 0 7 7 7 1 Penicillin-Binding Protein C-terminus Family Herpes_gE PF02480.11 EMC84241.1 - 5.7e-09 34.7 0.0 0.17 10.0 0.0 5.8 5 1 0 6 6 6 2 Alphaherpesvirus glycoprotein E C2-set PF05790.10 EMC84241.1 - 0.00064 19.6 3.5 46 4.0 0.0 7.1 9 0 0 9 9 9 0 Immunoglobulin C2-set domain fn3 PF00041.16 EMC84241.1 - 0.011 15.8 0.0 0.035 14.2 0.0 1.9 1 0 0 1 1 1 0 Fibronectin type III domain Herpes_gI PF01688.12 EMC84241.1 - 0.022 13.8 0.0 5.3 6.1 0.0 4.2 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I TRAPPC9-Trs120 PF08626.6 EMC84241.1 - 0.59 7.3 0.0 0.89 6.8 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TGF_beta PF00019.15 EMC84243.1 - 4e-17 62.4 2.2 1.9e-12 47.3 0.2 2.4 1 1 1 2 2 2 2 Transforming growth factor beta like domain LRR_4 PF12799.2 EMC84244.1 - 2.2e-16 59.0 18.4 8.2e-08 31.7 0.8 4.6 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC84244.1 - 3.5e-10 39.4 27.3 2.1e-06 27.3 3.0 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EMC84244.1 - 8e-06 25.1 14.6 1.9 8.7 0.0 7.0 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 EMC84244.1 - 0.00088 18.8 0.4 0.0019 17.7 0.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EMC84244.1 - 0.013 15.5 14.3 3.3 8.0 0.1 6.8 5 1 1 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 EMC84244.1 - 0.31 11.4 13.0 6.9 7.3 0.1 6.8 5 1 1 6 6 6 0 Leucine rich repeat HCO3_cotransp PF00955.16 EMC84245.1 - 5.4e-231 767.6 26.8 2.2e-139 465.4 8.3 2.3 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.8 EMC84245.1 - 2.7e-105 351.5 0.3 2.7e-105 351.5 0.2 2.6 3 0 0 3 3 3 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.17 EMC84245.1 - 6.2e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Paf1 PF03985.8 EMC84245.1 - 0.041 12.6 16.4 0.008 14.9 8.4 1.9 2 0 0 2 2 2 0 Paf1 Lectin_C PF00059.16 EMC84246.1 - 2.5e-123 404.1 53.7 5.5e-17 62.3 0.4 9.0 8 0 0 8 8 8 8 Lectin C-type domain fn2 PF00040.14 EMC84246.1 - 2.2e-16 59.5 13.0 1.5e-15 56.9 9.0 2.6 1 0 0 1 1 1 1 Fibronectin type II domain Herpes_UL45 PF05473.7 EMC84246.1 - 7.9e-15 54.8 5.1 0.00018 20.9 0.1 6.9 6 1 0 6 6 6 4 UL45 protein Xlink PF00193.12 EMC84246.1 - 0.00018 21.5 2.6 1.2 9.2 0.0 6.2 7 0 0 7 7 7 1 Extracellular link domain gp32 PF08804.5 EMC84246.1 - 0.0023 17.9 5.8 0.06 13.4 0.1 3.0 2 0 0 2 2 2 1 gp32 DNA binding protein like Chordopox_A33R PF05966.7 EMC84246.1 - 0.18 10.5 15.8 0.049 12.3 0.4 4.7 6 0 0 6 6 6 0 Chordopoxvirus A33R protein Integrin_beta PF00362.13 EMC84247.1 - 1.5e-176 587.4 0.3 2.6e-176 586.7 0.2 1.4 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 EMC84247.1 - 7e-20 70.1 0.6 1.1e-19 69.5 0.4 1.3 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.8 EMC84247.1 - 0.0003 20.8 17.8 0.0003 20.8 12.4 8.5 8 1 0 8 8 8 3 EGF-like domain hEGF PF12661.2 EMC84247.1 - 0.0061 16.5 13.1 0.011 15.7 1.7 6.2 7 0 0 7 7 7 2 Human growth factor-like EGF DUF2975 PF11188.3 EMC84247.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Cupredoxin_1 PF13473.1 EMC84247.1 - 0.072 12.9 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Cupredoxin-like domain DUF2970 PF11174.3 EMC84247.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) RRM_1 PF00076.17 EMC84248.1 - 5.9e-33 112.3 0.0 3e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84248.1 - 4.7e-26 90.5 0.0 1.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC84248.1 - 8.2e-14 51.2 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytadhesin_P30 PF07271.6 EMC84248.1 - 0.014 14.7 0.8 0.031 13.5 0.6 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 JAB PF01398.16 EMC84249.1 - 2.1e-35 120.8 0.1 6.5e-35 119.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMC84249.1 - 1.8e-31 108.5 4.6 3.8e-31 107.5 3.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EMC84249.1 - 7.4e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GPAT_N PF14829.1 EMC84249.1 - 0.029 14.0 1.3 0.052 13.2 0.1 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal HCO3_cotransp PF00955.16 EMC84250.1 - 5e-236 784.2 14.6 4e-235 781.2 10.1 1.9 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 EMC84250.1 - 2.6e-103 345.0 0.0 4.6e-103 344.2 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DPPIV_N PF00930.16 EMC84251.1 - 7e-112 373.5 7.9 1.1e-111 372.8 5.5 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMC84251.1 - 5.6e-54 182.5 2.5 1e-53 181.7 1.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC84251.1 - 2.6e-10 40.2 0.1 5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC84251.1 - 1.2e-05 25.3 0.0 0.00012 22.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMC84251.1 - 6.9e-05 22.2 0.5 0.00036 19.8 0.3 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMC84251.1 - 0.00063 19.2 2.5 0.0096 15.3 0.6 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIP PF03583.9 EMC84251.1 - 0.00078 18.7 0.1 0.002 17.4 0.1 1.6 1 0 0 1 1 1 1 Secretory lipase Peptidase_S15 PF02129.13 EMC84251.1 - 0.033 13.6 4.2 0.28 10.5 0.8 2.4 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) zf-RanBP PF00641.13 EMC84251.1 - 0.05 12.7 0.2 0.16 11.1 0.1 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Hormone_2 PF00123.15 EMC84252.1 - 2.4e-48 161.5 5.2 1.4e-16 59.9 0.5 3.3 3 0 0 3 3 3 3 Peptide hormone SBP_bac_8 PF13416.1 EMC84252.1 - 0.012 15.3 0.1 22 4.6 0.0 3.0 3 0 0 3 3 3 0 Bacterial extracellular solute-binding protein mIF3 PF14877.1 EMC84252.1 - 0.04 13.2 0.4 0.06 12.7 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Lipoprotein_10 PF03202.8 EMC84252.1 - 0.81 9.7 5.4 11 6.0 0.0 3.2 2 1 1 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region DPPIV_N PF00930.16 EMC84253.1 - 5.9e-104 347.4 8.0 8.4e-104 346.9 5.6 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMC84253.1 - 1.3e-55 187.9 1.1 2e-55 187.3 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC84253.1 - 1.3e-10 41.2 0.1 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC84253.1 - 5.5e-07 29.6 0.0 3.2e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EMC84253.1 - 0.0002 20.6 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S15 PF02129.13 EMC84253.1 - 0.00055 19.4 3.7 0.0029 17.0 0.2 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 EMC84253.1 - 0.00064 19.0 0.3 0.0014 17.8 0.2 1.5 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.11 EMC84253.1 - 0.0014 18.1 1.4 0.11 11.8 0.3 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 EMC84253.1 - 0.0039 16.4 0.7 0.02 14.2 0.5 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 EMC84253.1 - 0.0063 14.8 0.0 0.5 8.6 0.0 2.7 3 0 0 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.15 EMC84253.1 - 0.022 14.3 0.5 0.41 10.1 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 EMC84253.1 - 0.033 13.6 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ion_trans PF00520.26 EMC84254.1 - 4.6e-20 71.7 4.2 7.7e-20 71.0 2.9 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 EMC84254.1 - 8.3e-14 51.1 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 EMC84254.1 - 3e-12 46.0 0.0 1.2e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 Ion channel Transposase_22 PF02994.9 EMC84254.1 - 0.01 14.3 0.3 0.016 13.6 0.2 1.2 1 0 0 1 1 1 0 L1 transposable element Ion_trans_N PF08412.5 EMC84254.1 - 0.02 14.2 0.2 0.062 12.6 0.1 1.8 1 0 0 1 1 1 0 Ion transport protein N-terminal OppC_N PF12911.2 EMC84254.1 - 0.098 12.0 0.9 17 4.8 0.2 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3099 PF11298.3 EMC84254.1 - 0.25 11.1 1.4 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) AAA PF00004.24 EMC84255.1 - 1.1e-24 87.1 0.0 1.7e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC84255.1 - 5.1e-05 23.0 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 EMC84255.1 - 0.00026 20.8 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.1 EMC84255.1 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EMC84255.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC84255.1 - 0.04 14.0 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EMC84255.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus BPS PF08947.5 EMC84256.1 - 8.9e-28 95.6 0.3 1.6e-27 94.8 0.2 1.4 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.19 EMC84256.1 - 3.7e-17 61.9 0.5 6.9e-17 61.0 0.1 1.7 2 0 0 2 2 2 1 SH2 domain RA PF00788.18 EMC84256.1 - 1.3e-13 51.2 0.1 6.2e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 EMC84256.1 - 4e-08 33.3 0.1 9.6e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC84256.1 - 0.012 15.8 0.2 0.033 14.4 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.1 EMC84256.1 - 0.095 12.8 0.2 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Cobl PF09469.5 EMC84257.1 - 8e-32 109.0 1.5 2.4e-31 107.5 1.1 1.9 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain YukD PF08817.5 EMC84257.1 - 0.0051 17.3 0.1 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD TUG-UBL1 PF11470.3 EMC84257.1 - 0.038 13.9 0.2 0.54 10.2 0.1 2.6 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Aa_trans PF01490.13 EMC84258.1 - 8.9e-64 215.4 31.2 1e-63 215.2 21.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMC84258.1 - 4.3e-06 25.8 15.2 4.3e-06 25.8 10.5 2.1 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2371 PF10177.4 EMC84258.1 - 0.028 14.2 0.8 0.28 11.0 0.0 2.8 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) PIRT PF15099.1 EMC84258.1 - 8.9 5.5 8.2 0.72 9.0 0.3 2.8 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Glycos_transf_2 PF00535.21 EMC84260.1 - 1.4e-30 106.1 0.0 2.5e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC84260.1 - 6.7e-26 90.7 0.4 1.1e-25 90.0 0.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EMC84260.1 - 3.5e-11 42.4 0.0 1.2e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC84260.1 - 4.9e-09 35.6 0.0 0.001 18.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EMC84260.1 - 3.5e-08 33.5 0.0 5.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 EMC84260.1 - 0.046 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 EMC84260.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family group 2 TPR_11 PF13414.1 EMC84261.1 - 2.7e-48 161.4 71.9 5.5e-11 41.9 0.3 17.1 14 4 3 17 17 17 10 TPR repeat TPR_19 PF14559.1 EMC84261.1 - 4.1e-48 161.5 69.6 3.3e-07 30.5 2.2 17.6 14 4 6 20 20 18 12 Tetratricopeptide repeat TPR_16 PF13432.1 EMC84261.1 - 7.6e-45 150.7 51.3 4.5e-07 30.3 0.2 18.8 17 2 4 21 21 20 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMC84261.1 - 8.5e-45 147.0 74.6 7.1e-06 25.5 0.0 21.8 23 0 0 23 23 22 11 Tetratricopeptide repeat TPR_14 PF13428.1 EMC84261.1 - 1.4e-40 133.9 45.5 2.5e-05 24.4 0.0 21.5 15 6 7 23 23 22 8 Tetratricopeptide repeat TPR_1 PF00515.23 EMC84261.1 - 1.1e-34 116.6 60.0 1.6e-05 24.2 0.1 18.7 19 0 0 19 19 19 10 Tetratricopeptide repeat TPR_12 PF13424.1 EMC84261.1 - 1.6e-26 92.0 71.4 4.8e-06 26.4 0.5 17.1 9 6 10 19 19 19 12 Tetratricopeptide repeat Apc3 PF12895.2 EMC84261.1 - 5.7e-25 87.2 67.4 2.6e-06 27.4 3.7 13.0 8 6 7 15 15 15 9 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMC84261.1 - 4.7e-24 82.3 60.9 0.00019 20.9 0.0 18.0 21 0 0 21 21 17 6 Tetratricopeptide repeat TPR_7 PF13176.1 EMC84261.1 - 5.6e-23 78.8 33.3 2.1e-05 23.9 0.0 14.9 13 2 2 15 15 15 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMC84261.1 - 1.5e-19 68.4 24.8 0.013 15.6 0.2 15.8 17 0 0 17 17 15 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMC84261.1 - 1.1e-12 47.5 71.0 0.025 15.0 0.0 20.4 23 1 0 23 23 19 3 Tetratricopeptide repeat TPR_15 PF13429.1 EMC84261.1 - 1.1e-07 31.2 39.7 0.00082 18.5 2.0 8.0 5 2 2 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMC84261.1 - 4.5e-07 29.6 15.7 0.39 10.6 0.0 7.9 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_21 PF09976.4 EMC84261.1 - 2.1e-05 24.4 54.1 0.086 12.7 2.3 9.7 6 2 4 11 11 10 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC84261.1 - 0.00061 19.6 36.3 0.72 9.7 0.1 11.3 12 0 0 12 12 12 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EMC84261.1 - 0.00099 19.1 42.8 1.3 9.2 0.1 11.9 8 3 4 12 12 12 2 Tetratricopeptide repeat DUF2225 PF09986.4 EMC84261.1 - 0.001 18.5 28.8 0.0028 17.1 0.7 7.2 7 3 1 8 8 8 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 EMC84261.1 - 0.0061 16.4 27.1 0.41 10.6 0.1 11.2 12 0 0 12 12 11 1 Tetratricopeptide repeat SNAP PF14938.1 EMC84261.1 - 0.017 14.2 39.7 0.24 10.5 2.8 7.8 4 2 2 6 6 6 0 Soluble NSF attachment protein, SNAP Alkyl_sulf_dimr PF14863.1 EMC84261.1 - 1.2 9.3 14.7 4.9 7.3 0.4 5.9 4 1 0 5 5 5 0 Alkyl sulfatase dimerisation Ion_trans PF00520.26 EMC84262.1 - 2.1e-56 190.3 38.4 2.7e-50 170.4 14.7 2.5 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.7 EMC84262.1 - 2.1e-06 26.4 24.2 2.4e-05 22.9 0.6 3.3 2 1 1 3 3 3 3 Polycystin cation channel IQ PF00612.22 EMC84262.1 - 0.0015 17.9 1.6 0.0035 16.8 1.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ion_trans PF00520.26 EMC84263.1 - 1.1e-133 442.6 62.3 2.7e-73 245.5 9.1 4.1 4 0 0 4 4 4 3 Ion transport protein Na_trans_assoc PF06512.8 EMC84263.1 - 2.6e-60 204.3 6.2 2.6e-60 204.3 4.3 2.4 2 0 0 2 2 2 1 Sodium ion transport-associated DUF3451 PF11933.3 EMC84263.1 - 2.9e-59 200.5 10.0 2.9e-59 200.5 6.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3451) DICT PF10069.4 EMC84263.1 - 0.035 13.6 0.2 0.089 12.3 0.2 1.6 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems SPX PF03105.14 EMC84263.1 - 0.054 13.2 6.3 0.12 12.1 4.4 1.5 1 0 0 1 1 1 0 SPX domain Neur_chan_memb PF02932.11 EMC84263.1 - 0.41 10.4 6.4 1 9.1 0.0 3.2 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF3827 PF12877.2 EMC84263.1 - 0.51 8.3 2.9 0.83 7.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Nucleo_P87 PF07267.6 EMC84263.1 - 4.2 5.9 6.8 8.7 4.8 4.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Galactosyl_T PF01762.16 EMC84264.1 - 8.5e-61 204.9 0.0 1.1e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Pkinase PF00069.20 EMC84265.1 - 2.1e-62 210.6 0.0 3.1e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84265.1 - 1e-44 152.5 0.0 1.5e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.3 EMC84265.1 - 1.8e-12 46.6 0.0 4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C terminal Kinase-like PF14531.1 EMC84265.1 - 0.00039 19.4 0.0 0.00069 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC84265.1 - 0.093 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC84265.1 - 0.15 11.7 0.0 0.65 9.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family TRAM_LAG1_CLN8 PF03798.11 EMC84266.1 - 9.7e-37 126.4 23.8 1.2e-36 126.1 16.5 1.1 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 EMC84266.1 - 9.1e-07 28.4 0.7 1.6e-06 27.6 0.5 1.3 1 0 0 1 1 1 1 Homeobox domain Spindle_Spc25 PF08234.7 EMC84267.1 - 8.8e-26 89.7 0.4 2.1e-25 88.4 0.3 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EMC84267.1 - 3.2e-06 26.0 14.3 4.1e-06 25.6 9.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3584 PF12128.3 EMC84267.1 - 0.0024 15.3 11.7 0.0028 15.0 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) IFT57 PF10498.4 EMC84267.1 - 0.0035 16.1 11.5 0.0044 15.8 8.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Tox-ODYAM1 PF15642.1 EMC84267.1 - 0.024 13.3 8.8 0.037 12.6 6.1 1.4 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Atg14 PF10186.4 EMC84267.1 - 0.048 12.5 16.7 0.066 12.1 11.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0242 PF06785.6 EMC84267.1 - 0.24 10.0 8.7 0.33 9.5 6.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) V_ATPase_I PF01496.14 EMC84267.1 - 0.25 9.1 9.1 0.29 8.9 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C6 PF00851.13 EMC84267.1 - 0.51 8.8 6.4 0.69 8.4 4.4 1.1 1 0 0 1 1 1 0 Helper component proteinase DUF342 PF03961.8 EMC84267.1 - 0.87 7.9 12.8 1.1 7.6 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nup88 PF10168.4 EMC84267.1 - 0.98 7.1 12.2 1.2 6.9 8.5 1.1 1 0 0 1 1 1 0 Nuclear pore component Mnd1 PF03962.10 EMC84267.1 - 1.3 8.6 17.0 0.49 10.0 9.0 1.9 1 1 1 2 2 2 0 Mnd1 family IncA PF04156.9 EMC84267.1 - 1.6 8.3 18.8 0.35 10.4 10.0 1.9 1 1 1 2 2 2 0 IncA protein DUF1664 PF07889.7 EMC84267.1 - 1.9 8.3 9.5 5.2 6.8 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Dynamin_N PF00350.18 EMC84267.1 - 2.4 7.9 10.9 3.2 7.5 4.4 2.3 1 1 1 2 2 2 0 Dynamin family Seryl_tRNA_N PF02403.17 EMC84267.1 - 2.5 8.1 15.1 7.3 6.6 10.0 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.4 EMC84267.1 - 3.1 8.0 8.5 20 5.4 5.7 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) APG6 PF04111.7 EMC84267.1 - 5.7 5.8 16.4 5.8 5.8 10.8 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 EMC84267.1 - 7.1 6.7 13.5 3.9 7.5 7.3 1.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PAP2 PF01569.16 EMC84268.1 - 1.8e-14 53.4 6.8 1.8e-14 53.4 4.7 1.9 3 0 0 3 3 3 1 PAP2 superfamily SpoVAB PF13782.1 EMC84268.1 - 0.11 12.4 3.1 0.37 10.7 2.2 1.8 1 0 0 1 1 1 0 Stage V sporulation protein AB DUF4117 PF13491.1 EMC84268.1 - 0.26 10.7 9.2 0.21 11.0 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) ABC_membrane PF00664.18 EMC84269.1 - 3.3e-111 371.1 27.9 2.1e-68 230.7 2.9 3.6 3 1 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EMC84269.1 - 7.8e-74 246.4 0.6 1.4e-35 122.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC84269.1 - 6.2e-13 48.4 0.0 4.2e-06 26.1 0.4 3.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC84269.1 - 7.6e-09 35.9 0.0 0.033 14.1 0.0 4.1 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 EMC84269.1 - 3.6e-08 32.7 0.0 0.0019 17.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMC84269.1 - 4.1e-07 30.1 0.9 0.0024 17.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMC84269.1 - 2.3e-06 27.0 0.5 0.0075 15.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EMC84269.1 - 4.5e-06 25.5 1.8 0.076 11.5 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 EMC84269.1 - 5.5e-06 26.5 0.2 0.052 13.6 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMC84269.1 - 5.4e-05 24.0 0.0 0.15 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMC84269.1 - 9.8e-05 22.0 0.0 0.43 10.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMC84269.1 - 0.00017 20.7 0.4 0.022 13.8 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_28 PF13521.1 EMC84269.1 - 0.00044 20.2 0.0 7.9 6.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 EMC84269.1 - 0.00085 19.1 0.8 0.68 9.8 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EMC84269.1 - 0.0012 18.7 0.0 2.3 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EMC84269.1 - 0.002 17.5 4.8 1.1 8.6 0.8 3.8 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EMC84269.1 - 0.0025 17.3 0.5 5.8 6.2 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 EMC84269.1 - 0.0088 15.7 0.1 6.4 6.4 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMC84269.1 - 0.0097 15.7 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 SRP54 PF00448.17 EMC84269.1 - 0.013 14.9 0.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.15 EMC84269.1 - 0.016 13.9 0.0 2.8 6.5 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.17 EMC84269.1 - 0.049 13.8 0.0 8.8 6.5 0.0 3.2 3 0 0 3 3 2 0 RNA helicase APS_kinase PF01583.15 EMC84269.1 - 0.053 13.1 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.1 EMC84269.1 - 0.06 13.6 0.0 27 5.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.10 EMC84269.1 - 0.15 10.7 0.0 0.7 8.4 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein adh_short PF00106.20 EMC84271.1 - 4e-14 52.8 0.0 5.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EMC84271.1 - 0.0094 15.1 0.0 0.037 13.1 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EMC84271.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Ldl_recept_a PF00057.13 EMC84272.1 - 0 1097.9 691.1 2.1e-12 46.7 5.0 38.4 38 0 0 38 38 38 36 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 EMC84272.1 - 3.3e-207 670.6 96.6 1.6e-11 44.2 0.0 38.1 39 0 0 39 39 39 31 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 EMC84272.1 - 7.4e-63 208.3 347.4 6.3e-10 39.0 4.1 24.5 23 1 0 23 23 23 16 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC84272.1 - 3.9e-25 87.1 151.3 1e-08 34.6 1.5 18.4 18 0 0 18 18 18 10 Complement Clr-like EGF-like SGL PF08450.7 EMC84272.1 - 1.1e-15 57.7 26.1 0.088 12.1 0.6 15.0 9 7 5 15 15 15 5 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EMC84272.1 - 0.00016 21.5 0.0 93 3.1 0.0 8.9 11 1 1 12 12 12 0 Arylesterase Collagen PF01391.13 EMC84273.1 - 5.1e-65 214.9 274.9 2.4e-09 36.6 15.9 11.6 2 2 5 7 7 7 5 Collagen triple helix repeat (20 copies) VWA PF00092.23 EMC84273.1 - 4.9e-63 212.0 0.9 1.6e-39 135.4 0.2 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 EMC84273.1 - 3e-22 79.5 0.1 1.3e-12 48.1 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain Kunitz_BPTI PF00014.18 EMC84273.1 - 5.6e-19 68.0 6.9 1.2e-18 66.9 4.8 1.6 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain VWA_3 PF13768.1 EMC84273.1 - 4.3e-08 32.9 0.0 0.00068 19.3 0.0 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF1448 PF07289.6 EMC84274.1 - 3.8e-152 506.0 0.1 4.3e-152 505.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Vps36_ESCRT-II PF11605.3 EMC84274.1 - 3.7e-05 23.4 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 EMC84274.1 - 4.4e-05 23.6 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain GRAM PF02893.15 EMC84274.1 - 6e-05 22.4 0.0 0.0081 15.6 0.0 2.4 2 0 0 2 2 2 2 GRAM domain Voldacs PF03517.8 EMC84274.1 - 0.012 15.4 1.4 0.39 10.5 0.0 2.9 2 1 0 3 3 3 0 Regulator of volume decrease after cellular swelling Kelch_1 PF01344.20 EMC84275.1 - 5.3e-46 153.9 0.0 3.2e-11 42.5 0.0 5.6 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 EMC84275.1 - 8.5e-31 105.8 0.6 2.1e-30 104.5 0.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 EMC84275.1 - 2.1e-29 100.4 0.1 3.9e-09 36.2 0.0 5.6 1 1 4 5 5 5 4 Kelch motif BTB PF00651.26 EMC84275.1 - 8.1e-29 99.8 1.3 1.3e-28 99.2 0.4 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 EMC84275.1 - 2.5e-24 84.7 0.6 1.3e-07 31.2 0.0 5.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC84275.1 - 1.7e-21 75.7 0.0 1.8e-05 24.7 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC84275.1 - 4.1e-17 61.1 0.1 0.16 11.7 0.0 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.1 EMC84275.1 - 5.3e-14 51.7 0.0 0.12 12.3 0.0 5.5 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.3 EMC84275.1 - 0.0014 17.8 0.6 0.0031 16.7 0.2 1.6 1 1 0 2 2 2 1 Domain of unknown function (DUF3342) FAST_2 PF08368.7 EMC84276.1 - 9.4e-29 99.6 0.4 1.6e-27 95.6 0.0 3.0 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.10 EMC84276.1 - 2.5e-18 65.5 19.4 3.2e-17 61.9 2.4 4.9 6 0 0 6 6 6 3 FAST kinase-like protein, subdomain 1 RAP PF08373.5 EMC84276.1 - 6.7e-15 54.6 0.1 2.1e-14 53.0 0.0 2.0 1 0 0 1 1 1 1 RAP domain Pro_isomerase PF00160.16 EMC84277.1 - 1.8e-47 161.4 0.4 1.8e-47 161.4 0.3 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 EMC84277.1 - 5.5e-07 29.2 40.3 5.5e-07 29.2 27.9 5.6 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein Trichoplein PF13868.1 EMC84278.1 - 3.5e-09 35.5 128.5 3.5e-09 35.5 89.1 2.1 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin Put_Phosphatase PF06888.7 EMC84279.1 - 2.4e-91 305.1 0.0 2.7e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 EMC84279.1 - 8e-10 39.1 0.0 1.1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC84279.1 - 0.0031 17.7 0.2 0.016 15.4 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Kelch_1 PF01344.20 EMC84280.1 - 9.5e-52 172.3 32.5 7e-13 47.9 0.3 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EMC84280.1 - 8.4e-39 130.1 12.9 3.3e-09 36.5 0.0 6.3 2 2 4 6 6 6 6 Kelch motif BTB PF00651.26 EMC84280.1 - 4.4e-31 107.1 1.2 6.9e-31 106.5 0.8 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 EMC84280.1 - 7.1e-31 105.7 3.6 4.5e-06 26.3 0.1 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain BACK PF07707.10 EMC84280.1 - 2.4e-25 88.3 5.9 3e-25 88.0 2.1 2.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 EMC84280.1 - 2.1e-23 81.1 16.2 1.4e-05 24.6 0.0 7.2 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EMC84280.1 - 4.7e-21 74.3 3.3 7.5e-06 25.9 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC84280.1 - 3.3e-09 36.4 21.8 0.0017 18.2 0.2 6.8 7 0 0 7 7 7 4 Kelch motif DUF3342 PF11822.3 EMC84280.1 - 9.7e-05 21.6 0.3 0.00017 20.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) RRM_3 PF08777.6 EMC84281.1 - 1.6e-32 111.4 1.9 1.6e-32 111.4 1.3 3.1 3 1 0 3 3 3 1 RNA binding motif La PF05383.12 EMC84281.1 - 1.5e-23 82.3 0.1 2.7e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EMC84281.1 - 4.6e-15 55.0 0.2 1.4e-09 37.4 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84281.1 - 3.1e-13 49.4 0.0 6e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC84281.1 - 0.0043 16.8 1.0 3.6 7.5 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 EMC84281.1 - 1.1 8.8 12.8 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 IncA protein MTS PF05175.9 EMC84282.1 - 2.3e-14 53.1 0.1 3.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMC84282.1 - 1.5e-11 43.9 0.2 2.4e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EMC84282.1 - 1.2e-10 41.4 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC84282.1 - 2.2e-10 40.3 0.2 2.9e-10 39.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMC84282.1 - 7.5e-09 35.2 0.0 9.8e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 EMC84282.1 - 1.2e-08 34.6 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EMC84282.1 - 5.9e-08 33.2 0.0 8.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EMC84282.1 - 1.1e-06 28.3 0.2 1.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 EMC84282.1 - 0.00013 22.2 0.6 0.00022 21.5 0.4 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC84282.1 - 0.00044 20.6 0.1 0.00082 19.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84282.1 - 0.00064 20.1 0.1 0.0018 18.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EMC84282.1 - 0.0016 17.4 0.3 0.0026 16.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) N6_Mtase PF02384.11 EMC84282.1 - 0.0046 16.0 0.2 0.015 14.3 0.1 1.9 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_4 PF02390.12 EMC84282.1 - 0.0089 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DNA_methylase PF00145.12 EMC84282.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_23 PF13489.1 EMC84282.1 - 0.019 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EMC84282.1 - 0.022 13.4 0.5 0.033 12.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 EMC84282.1 - 0.053 12.9 0.6 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Putative methyltransferase DUF2431 PF10354.4 EMC84282.1 - 0.097 12.6 0.1 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) CRAL_TRIO PF00650.15 EMC84283.1 - 0.009 15.5 0.4 0.031 13.7 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO domain zf-C3HC4 PF00097.20 EMC84283.1 - 0.012 15.2 0.5 0.012 15.2 0.4 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NYAP_C PF15452.1 EMC84283.1 - 0.39 9.6 3.7 0.43 9.5 0.3 2.2 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Myosin_head PF00063.16 EMC84284.1 - 7.2e-197 655.5 1.3 8.6e-197 655.3 0.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.20 EMC84284.1 - 2.1e-61 207.3 0.0 3.3e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84284.1 - 1.2e-41 142.5 0.0 2e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC84284.1 - 1.7e-06 27.9 0.0 0.071 12.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family IQ PF00612.22 EMC84284.1 - 3.5e-06 26.1 4.2 0.00092 18.6 0.0 3.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif Kinase-like PF14531.1 EMC84284.1 - 1.9e-05 23.7 0.0 4.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like AAA_22 PF13401.1 EMC84284.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMC84284.1 - 0.061 12.4 0.0 0.16 11.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin GRASP55_65 PF04495.9 EMC84285.1 - 5.7e-78 259.6 0.0 7.4e-63 210.6 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EMC84285.1 - 4.2e-05 23.3 0.0 0.052 13.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Pkinase PF00069.20 EMC84286.1 - 1.6e-57 194.6 0.3 4e-57 193.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84286.1 - 9.7e-35 119.8 0.0 2.2e-34 118.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Methyltransf_23 PF13489.1 EMC84287.1 - 3.3e-13 49.6 0.0 6.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84287.1 - 6.5e-12 45.7 0.0 1.8e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC84287.1 - 1e-10 41.9 0.0 2.5e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC84287.1 - 1.5e-09 38.0 0.1 3.9e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC84287.1 - 6.5e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC84287.1 - 1.2e-05 25.8 0.0 2.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC84287.1 - 8.8e-05 22.5 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EMC84287.1 - 0.0029 18.4 0.0 0.0084 16.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain CheR PF01739.13 EMC84287.1 - 0.0059 15.9 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.6 EMC84287.1 - 0.016 14.6 0.0 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.12 EMC84287.1 - 0.034 13.5 1.0 4.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EMC84287.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Gal-bind_lectin PF00337.17 EMC84287.1 - 1.2 8.4 5.1 11 5.3 3.3 2.2 1 1 0 1 1 1 0 Galactoside-binding lectin Dynein_IC2 PF11540.3 EMC84289.1 - 1.3e-18 66.0 0.4 2.3e-18 65.2 0.3 1.5 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.27 EMC84289.1 - 1.9e-15 56.0 13.0 8.7e-06 25.4 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Mito_carr PF00153.22 EMC84290.1 - 3.2e-74 244.7 0.9 2.4e-26 91.2 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EMC84290.1 - 2.2e-12 46.9 2.3 0.00012 22.0 0.5 4.4 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC84290.1 - 3.6e-12 44.6 4.5 0.019 14.2 0.0 5.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EMC84290.1 - 1e-10 40.5 1.9 0.017 14.9 0.0 6.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 EMC84290.1 - 3.3e-06 26.5 0.3 0.011 15.3 0.0 4.4 4 1 1 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC84290.1 - 0.00013 21.1 0.9 5 6.6 0.0 4.0 3 0 0 3 3 3 2 EF hand EF-hand_like PF09279.6 EMC84290.1 - 0.081 12.9 0.6 6 6.9 0.2 2.7 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Hat1_N PF10394.4 EMC84291.1 - 8.8e-49 165.6 0.9 3.1e-48 163.9 0.6 1.9 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EMC84291.1 - 8.1e-05 22.7 0.0 0.0005 20.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC84291.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M24 PF00557.19 EMC84292.1 - 4.8e-51 173.2 0.0 6.6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Homeobox PF00046.24 EMC84293.1 - 7e-21 73.5 3.2 1.1e-20 72.9 2.2 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC84293.1 - 0.017 14.7 0.1 0.06 13.0 0.0 1.9 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.3 EMC84293.1 - 0.093 11.8 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DLL_N PF12413.3 EMC84294.1 - 5e-16 59.5 10.8 8.7e-16 58.7 7.5 1.4 1 0 0 1 1 1 1 Homeobox protein distal-less-like N terminal Homeobox PF00046.24 EMC84294.1 - 4e-11 42.3 0.5 5.5e-11 41.9 0.3 1.2 1 0 0 1 1 1 1 Homeobox domain GP38 PF05268.6 EMC84294.1 - 0.0097 15.3 4.6 0.012 15.0 3.2 1.0 1 0 0 1 1 1 1 Phage tail fibre adhesin Gp38 DmpG_comm PF07836.6 EMC84294.1 - 0.033 13.6 0.7 0.2 11.0 0.1 2.1 2 0 0 2 2 2 0 DmpG-like communication domain Integrin_alpha2 PF08441.7 EMC84295.1 - 2.2e-113 379.5 7.3 3.4e-113 378.9 5.0 1.3 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 EMC84295.1 - 2.8e-17 61.8 21.5 3.3e-07 29.7 4.0 3.8 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 EMC84295.1 - 2.4e-13 50.2 9.9 6e-10 39.3 1.8 3.1 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 EMC84295.1 - 9.6e-05 21.8 1.0 9.6e-05 21.8 0.7 2.5 3 0 0 3 3 3 1 Integrin alpha cytoplasmic region LRR19-TM PF15176.1 EMC84295.1 - 0.048 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain BCDHK_Adom3 PF10436.4 EMC84296.1 - 3.7e-54 182.6 0.0 5.6e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMC84296.1 - 4.1e-21 74.7 0.0 7.3e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC84296.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PDZ PF00595.19 EMC84297.1 - 2.9e-14 52.9 1.6 8.9e-14 51.4 1.1 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 EMC84297.1 - 9.9e-10 38.1 0.4 2.4e-09 36.9 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC84297.1 - 6.7e-08 32.5 2.6 8.6e-08 32.2 0.6 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC84297.1 - 0.00047 19.8 1.5 0.0013 18.4 1.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ_2 PF13180.1 EMC84297.1 - 0.0023 17.7 0.6 0.0088 15.9 0.4 2.0 1 0 0 1 1 1 1 PDZ domain DUF2407_C PF13373.1 EMC84297.1 - 0.11 12.4 3.1 0.31 10.9 2.2 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF1515 PF07439.6 EMC84297.1 - 0.55 10.0 2.7 0.89 9.3 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Tropomyosin PF00261.15 EMC84297.1 - 0.63 9.0 39.4 0.97 8.4 20.0 3.4 3 0 0 3 3 3 0 Tropomyosin SlyX PF04102.7 EMC84297.1 - 1.4 9.3 12.9 0.061 13.6 1.4 3.8 4 0 0 4 4 4 0 SlyX APG6 PF04111.7 EMC84297.1 - 9.2 5.1 29.5 0.75 8.7 16.5 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Membr_traf_MHD PF10540.4 EMC84298.1 - 9.4e-57 190.6 0.9 9.4e-57 190.6 0.6 2.4 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.12 EMC84298.1 - 1.9e-42 143.7 1.6 2.6e-42 143.2 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C2 PF00168.25 EMC84298.1 - 6e-36 122.1 10.7 8.1e-25 86.4 0.2 3.5 4 0 0 4 4 4 2 C2 domain C1_1 PF00130.17 EMC84298.1 - 3.6e-10 39.3 5.9 8.4e-10 38.2 4.1 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HAD PF12710.2 EMC84299.1 - 5.6e-16 59.2 0.5 1.8e-15 57.6 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC84299.1 - 6.7e-15 54.7 0.0 1.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMC84299.1 - 1.8e-12 48.1 0.1 6.3e-05 23.4 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC84299.1 - 3.4e-10 39.7 0.0 1.3e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC84299.1 - 0.00026 20.6 0.0 0.001 18.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC84299.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RUN PF02759.14 EMC84300.1 - 3.1e-19 69.0 0.1 6.4e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 RUN domain SH3_9 PF14604.1 EMC84300.1 - 4e-10 39.1 0.0 1.2e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC84300.1 - 1.3e-07 30.8 0.6 2.3e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMC84300.1 - 5.4e-07 28.9 0.0 1.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Y_phosphatase PF00102.22 EMC84301.1 - 9e-104 345.9 0.1 1.3e-85 286.5 0.1 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EMC84301.1 - 5e-07 29.3 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC84301.1 - 0.00041 20.6 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Gly_kinase PF02595.10 EMC84301.1 - 0.03 13.0 0.0 0.57 8.8 0.0 2.0 2 0 0 2 2 2 0 Glycerate kinase family PTPlike_phytase PF14566.1 EMC84301.1 - 0.06 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 EMC84302.1 - 3.3e-18 65.8 0.1 3.5e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC84302.1 - 6.4e-06 25.7 0.1 8.2e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase_Tyr PF07714.12 EMC84303.1 - 3.9e-38 130.9 0.0 4.9e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC84303.1 - 5.7e-37 127.2 0.0 7.9e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EMC84303.1 - 0.0069 15.4 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family IncA PF04156.9 EMC84305.1 - 8.1e-06 25.5 3.7 1.3e-05 24.8 2.6 1.2 1 0 0 1 1 1 1 IncA protein HemX PF04375.9 EMC84305.1 - 0.0032 16.1 3.6 0.0042 15.7 2.5 1.1 1 0 0 1 1 1 1 HemX Ly49 PF08391.5 EMC84305.1 - 0.0081 16.2 0.5 0.043 13.9 0.4 2.0 1 1 0 1 1 1 1 Ly49-like protein, N-terminal region Spc7 PF08317.6 EMC84305.1 - 0.01 14.4 3.5 0.014 14.0 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Bestrophin PF01062.16 EMC84305.1 - 0.012 14.5 0.7 0.018 13.9 0.5 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel IFT57 PF10498.4 EMC84305.1 - 0.02 13.6 1.2 0.026 13.2 0.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Cast PF10174.4 EMC84305.1 - 0.02 12.9 5.0 0.025 12.6 3.5 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone 7tm_1 PF00001.16 EMC84305.1 - 0.023 13.8 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4446 PF14584.1 EMC84305.1 - 0.024 14.4 0.8 3.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) CENP-F_leu_zip PF10473.4 EMC84305.1 - 0.036 13.9 7.1 0.051 13.4 4.9 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2681 PF10883.3 EMC84305.1 - 0.043 14.0 2.1 4.9 7.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Dynamitin PF04912.9 EMC84305.1 - 0.044 12.5 2.1 0.059 12.1 1.5 1.2 1 0 0 1 1 1 0 Dynamitin OmpH PF03938.9 EMC84305.1 - 0.059 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 EMC84305.1 - 0.072 11.5 1.7 0.093 11.1 1.2 1.0 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EMC84305.1 - 0.078 12.0 6.0 0.11 11.5 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EMC84305.1 - 0.11 10.9 0.3 0.15 10.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Val_tRNA-synt_C PF10458.4 EMC84305.1 - 0.16 12.0 0.4 0.16 12.0 0.2 2.3 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Bacillus_HBL PF05791.6 EMC84305.1 - 0.16 11.3 0.6 0.22 10.8 0.4 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 EMC84305.1 - 0.18 11.5 1.5 0.92 9.3 1.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TarH PF02203.10 EMC84305.1 - 0.24 11.2 3.7 4.5 7.0 0.3 2.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue Snapin_Pallidin PF14712.1 EMC84305.1 - 0.42 10.9 3.1 1.3 9.3 1.0 2.1 1 1 1 2 2 2 0 Snapin/Pallidin TBPIP PF07106.8 EMC84305.1 - 0.49 9.9 2.8 0.78 9.2 1.7 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 EMC84305.1 - 0.56 9.6 7.5 1.6 8.1 5.3 1.5 1 1 0 1 1 1 0 Intermediate filament protein Prefoldin_2 PF01920.15 EMC84305.1 - 0.75 9.5 5.1 8.1 6.2 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit ERM PF00769.14 EMC84305.1 - 0.84 9.1 8.7 1.4 8.4 6.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SlyX PF04102.7 EMC84305.1 - 0.85 10.0 3.8 13 6.2 0.0 2.3 1 1 1 2 2 2 0 SlyX DUF2968 PF11180.3 EMC84305.1 - 1.3 8.4 8.9 1.7 8.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF724 PF05266.9 EMC84305.1 - 1.4 8.5 5.4 2.2 7.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 EMC84305.1 - 6.3 6.6 11.0 4 7.3 1.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EMC84306.1 - 0.00026 20.8 12.1 0.00033 20.5 8.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EMC84306.1 - 0.00037 20.1 13.1 0.00098 18.7 9.2 1.4 1 1 0 1 1 1 1 IncA protein Lectin_C PF00059.16 EMC84306.1 - 0.0005 20.6 1.4 0.71 10.5 0.1 2.7 3 0 0 3 3 2 2 Lectin C-type domain HemX PF04375.9 EMC84306.1 - 0.00067 18.3 3.2 0.001 17.7 2.2 1.3 1 0 0 1 1 1 1 HemX Fez1 PF06818.10 EMC84306.1 - 0.00079 19.4 6.7 0.0011 19.0 4.7 1.1 1 0 0 1 1 1 1 Fez1 DUF2681 PF10883.3 EMC84306.1 - 0.007 16.5 7.1 0.17 12.0 2.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2681) Spc7 PF08317.6 EMC84306.1 - 0.018 13.7 8.5 0.027 13.1 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 EMC84306.1 - 0.023 14.5 9.7 0.032 14.0 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EMC84306.1 - 0.031 13.4 1.1 0.044 12.9 0.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Ly49 PF08391.5 EMC84306.1 - 0.036 14.2 2.0 0.093 12.8 1.4 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Herpes_gE PF02480.11 EMC84306.1 - 0.04 12.1 1.6 0.08 11.2 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E APG6 PF04111.7 EMC84306.1 - 0.041 12.9 9.9 0.056 12.4 6.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 7tm_1 PF00001.16 EMC84306.1 - 0.043 12.9 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TMF_DNA_bd PF12329.3 EMC84306.1 - 0.044 13.5 10.9 0.14 12.0 0.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cast PF10174.4 EMC84306.1 - 0.044 11.8 11.3 0.055 11.5 7.8 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone WEMBL PF05701.6 EMC84306.1 - 0.065 11.6 9.5 0.082 11.3 6.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light MscS_porin PF12795.2 EMC84306.1 - 0.11 11.7 19.5 0.15 11.3 13.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF342 PF03961.8 EMC84306.1 - 0.19 10.1 1.0 0.24 9.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 EMC84306.1 - 0.22 9.9 4.8 0.28 9.6 3.3 1.0 1 0 0 1 1 1 0 AAA domain GspL_C PF12693.2 EMC84306.1 - 0.37 10.5 11.7 1.8 8.3 4.7 2.4 1 1 1 2 2 2 0 GspL periplasmic domain Macoilin PF09726.4 EMC84306.1 - 0.4 8.8 6.0 0.54 8.4 4.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DivIC PF04977.10 EMC84306.1 - 1.7 8.1 7.0 1.6 8.2 1.5 2.2 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.1 EMC84306.1 - 2 7.5 9.9 2.8 7.0 6.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EMC84306.1 - 2.1 8.7 6.7 4 7.8 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EMC84306.1 - 2.2 8.0 4.5 19 5.0 3.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) OmpH PF03938.9 EMC84306.1 - 2.4 8.0 10.8 3.9 7.3 7.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Snapin_Pallidin PF14712.1 EMC84306.1 - 2.4 8.4 8.9 11 6.4 3.5 2.2 1 1 1 2 2 2 0 Snapin/Pallidin DUF2968 PF11180.3 EMC84306.1 - 3.1 7.1 16.4 4.4 6.6 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Prefoldin_2 PF01920.15 EMC84306.1 - 3.4 7.4 11.8 3.3 7.5 2.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit SlyX PF04102.7 EMC84306.1 - 4.5 7.7 13.1 1.4 9.3 2.7 2.3 1 1 1 2 2 2 0 SlyX DUF4200 PF13863.1 EMC84306.1 - 9.2 6.2 12.6 43 4.0 8.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3522 PF12036.3 EMC84308.1 - 5.1e-12 45.9 3.6 7.9e-12 45.3 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) ANF_receptor PF01094.23 EMC84311.1 - 5.4e-21 74.7 0.2 6.5e-21 74.5 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EMC84311.1 - 0.02 14.2 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein PSP94 PF05825.6 EMC84312.1 - 3e-10 40.2 5.8 4e-10 39.8 4.0 1.1 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.13 EMC84312.1 - 0.0044 17.0 4.7 0.0095 16.0 3.3 1.7 1 1 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.2 EMC84312.1 - 0.1 12.3 8.4 0.29 10.8 5.8 1.9 1 1 0 1 1 1 0 TILa domain Rgp1 PF08737.5 EMC84313.1 - 6.8e-76 255.9 2.2 4.6e-39 134.6 0.2 3.1 1 1 2 3 3 3 3 Rgp1 DUF608 PF04685.8 EMC84314.1 - 1.9e-140 467.7 2.1 2.6e-140 467.2 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GBA2_N PF12215.3 EMC84314.1 - 3.6e-45 154.4 0.0 5.7e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal GDE_C PF06202.9 EMC84314.1 - 0.00072 18.3 0.1 0.0011 17.7 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Avidin PF01382.12 EMC84315.1 - 2.9e-36 124.2 4.0 3.3e-36 124.0 2.8 1.0 1 0 0 1 1 1 1 Avidin family CD36 PF01130.16 EMC84315.1 - 0.054 11.7 0.1 0.057 11.7 0.0 1.0 1 0 0 1 1 1 0 CD36 family Avidin PF01382.12 EMC84316.1 - 6.4e-31 106.9 0.0 7.2e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Avidin family SPDY PF03771.11 EMC84316.1 - 0.038 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Avidin PF01382.12 EMC84317.1 - 7.3e-31 106.7 0.3 8.3e-31 106.6 0.2 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.12 EMC84318.1 - 6.8e-26 90.8 1.2 7.9e-26 90.5 0.8 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.12 EMC84319.1 - 3.4e-22 78.8 0.0 3.8e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Avidin family bZIP_1 PF00170.16 EMC84320.1 - 5.8e-12 45.3 15.4 5.8e-12 45.3 10.7 2.1 2 1 1 3 3 2 2 bZIP transcription factor bZIP_2 PF07716.10 EMC84320.1 - 4.9e-10 39.0 13.1 4.9e-10 39.0 9.0 2.8 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.12 EMC84320.1 - 3e-06 27.4 12.2 5.4e-06 26.6 8.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ADIP PF11559.3 EMC84320.1 - 0.012 15.5 13.5 0.017 15.0 9.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.9 EMC84320.1 - 0.023 14.6 2.8 0.027 14.4 1.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EMC84320.1 - 0.031 13.8 8.3 0.052 13.1 5.7 1.5 1 1 0 1 1 1 0 IncA protein OS-D PF03392.8 EMC84320.1 - 0.065 13.2 3.0 0.097 12.6 2.0 1.3 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Fib_alpha PF08702.5 EMC84320.1 - 0.27 11.3 6.7 0.31 11.1 4.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EMC84320.1 - 0.42 8.4 3.6 0.45 8.3 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EMC84320.1 - 0.61 8.9 9.3 0.72 8.7 6.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GCN5L1 PF06320.8 EMC84320.1 - 0.74 9.6 5.9 0.99 9.2 4.1 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) HAUS-augmin3 PF14932.1 EMC84320.1 - 0.96 8.5 8.2 1.3 8.1 5.7 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DivIC PF04977.10 EMC84320.1 - 2.2 7.8 8.5 1.1 8.8 3.5 2.1 1 1 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EMC84320.1 - 5.4 7.3 12.2 0.085 13.1 1.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EMC84320.1 - 6.9 7.0 10.1 0.72 10.2 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Aph-1 PF06105.7 EMC84321.1 - 1.3e-80 270.1 10.6 1.4e-80 269.9 7.4 1.0 1 0 0 1 1 1 1 Aph-1 protein YqfD PF06898.6 EMC84321.1 - 0.28 9.8 0.5 0.37 9.4 0.3 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD DUF3139 PF11337.3 EMC84321.1 - 0.69 10.2 0.1 0.69 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Carb_anhydrase PF00194.16 EMC84323.1 - 2.3e-76 256.1 0.0 2.6e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DDT PF02791.12 EMC84323.1 - 0.1 12.4 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 DDT domain Collagen PF01391.13 EMC84324.1 - 1.4e-14 53.3 48.4 6.2e-08 32.0 18.2 2.4 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.1 EMC84324.1 - 6.1e-12 45.4 23.3 1.4e-09 37.8 7.3 2.7 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 EMC84324.1 - 1.2e-09 38.0 9.7 1.2e-09 38.0 6.7 2.8 2 1 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 EMC84324.1 - 8.6e-08 31.6 14.1 4.5e-06 26.1 2.8 3.2 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 EMC84324.1 - 2.2e-05 24.3 18.4 0.0014 18.5 3.6 3.0 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.2 EMC84324.1 - 0.0012 18.7 19.9 0.032 14.1 1.4 2.8 2 0 0 2 2 2 2 EGF domain Tme5_EGF_like PF09064.5 EMC84324.1 - 0.19 11.3 16.3 0.44 10.1 2.2 2.7 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like hEGF PF12661.2 EMC84324.1 - 0.42 10.8 6.6 7.9 6.8 0.3 3.5 2 0 0 2 2 2 0 Human growth factor-like EGF Keratin PF02422.11 EMC84326.1 - 1.4e-41 140.4 15.5 1.5e-41 140.3 10.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC84327.1 - 1.6e-41 140.1 16.5 1.8e-41 140.0 11.4 1.0 1 0 0 1 1 1 1 Keratin zf-U11-48K PF05253.7 EMC84329.1 - 2.8e-22 77.9 10.0 7e-12 44.7 0.2 2.2 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger zf-TRAF PF02176.13 EMC84329.1 - 0.04 14.2 5.3 0.57 10.5 0.1 2.6 2 1 1 3 3 3 0 TRAF-type zinc finger V-SNARE_C PF12352.3 EMC84330.1 - 1.3e-17 63.5 4.3 1.4e-17 63.5 1.0 2.3 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMC84330.1 - 2.1e-05 24.1 0.4 4.3e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Sec20 Ran-binding PF05508.6 EMC84330.1 - 0.0017 17.3 1.8 0.0024 16.8 1.2 1.2 1 0 0 1 1 1 1 RanGTP-binding protein V-SNARE PF05008.10 EMC84330.1 - 0.0038 17.3 1.6 0.0093 16.1 1.1 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus SLX9 PF15341.1 EMC84330.1 - 0.045 14.2 0.9 0.055 13.8 0.6 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 REV PF00424.13 EMC84330.1 - 0.22 11.4 3.1 1.8 8.5 0.7 2.4 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) Fmp27_WPPW PF10359.4 EMC84330.1 - 0.8 8.0 7.5 0.66 8.3 3.8 1.7 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 EMC84330.1 - 0.93 9.0 6.7 1.6 8.3 4.2 1.7 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 EMC84330.1 - 1.3 9.0 4.0 2.3 8.1 0.2 2.2 1 1 1 2 2 2 0 FlxA-like protein wnt PF00110.14 EMC84331.1 - 2.7e-97 325.6 16.3 3.3e-97 325.4 11.3 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.14 EMC84332.1 - 9.6e-121 402.7 16.0 1.1e-120 402.5 11.1 1.0 1 0 0 1 1 1 1 wnt family AAA PF00004.24 EMC84333.1 - 7.1e-58 194.5 0.0 1.2e-41 141.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMC84333.1 - 1.5e-14 53.6 0.0 2.2e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EMC84333.1 - 2.7e-14 52.5 0.1 2.7e-14 52.5 0.1 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EMC84333.1 - 1.3e-09 38.2 0.2 0.0023 18.0 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMC84333.1 - 1.6e-09 38.6 0.0 0.002 18.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EMC84333.1 - 4.3e-09 36.3 0.0 0.0033 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMC84333.1 - 4.7e-08 33.1 0.0 0.011 15.8 0.0 3.4 4 0 0 4 4 2 2 RNA helicase AAA_2 PF07724.9 EMC84333.1 - 5e-08 33.0 0.0 6.4e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMC84333.1 - 1.2e-07 30.9 0.0 0.01 14.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMC84333.1 - 6e-07 29.2 0.1 0.00077 19.2 0.1 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMC84333.1 - 1.1e-06 28.5 0.0 0.056 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EMC84333.1 - 2.9e-06 26.2 0.0 0.04 12.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EMC84333.1 - 6.3e-06 25.8 0.1 0.11 12.3 0.0 3.0 3 0 0 3 3 3 2 Part of AAA domain AAA_16 PF13191.1 EMC84333.1 - 6.6e-06 26.2 0.0 0.0054 16.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EMC84333.1 - 8.8e-06 26.0 0.0 0.02 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EMC84333.1 - 1e-05 24.7 0.1 0.0037 16.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EMC84333.1 - 3.1e-05 23.1 0.0 0.28 10.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 EMC84333.1 - 0.00011 21.9 0.0 0.66 9.6 0.0 3.6 3 1 0 3 3 3 2 NACHT domain Arch_ATPase PF01637.13 EMC84333.1 - 0.00017 21.3 0.1 0.25 10.9 0.1 3.4 2 2 1 3 3 3 1 Archaeal ATPase KTI12 PF08433.5 EMC84333.1 - 0.00041 19.6 0.3 1.1 8.4 0.0 3.2 3 0 0 3 3 3 2 Chromatin associated protein KTI12 KaiC PF06745.8 EMC84333.1 - 0.00095 18.3 0.1 0.017 14.2 0.0 2.8 2 1 1 3 3 3 1 KaiC AAA_25 PF13481.1 EMC84333.1 - 0.0012 18.2 0.1 1.1 8.6 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.1 EMC84333.1 - 0.0013 18.7 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EMC84333.1 - 0.0019 17.7 0.0 0.29 10.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMC84333.1 - 0.0022 17.4 0.0 0.15 11.4 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.22 EMC84333.1 - 0.003 17.8 0.0 0.015 15.6 0.0 2.1 2 0 0 2 2 1 1 ABC transporter UPF0079 PF02367.12 EMC84333.1 - 0.0031 17.1 0.1 0.47 10.1 0.0 2.9 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EMC84333.1 - 0.0036 16.8 0.0 1.4 8.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EMC84333.1 - 0.01 15.4 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EMC84333.1 - 0.015 14.1 0.0 1.9 7.2 0.0 2.6 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EMC84333.1 - 0.021 13.7 0.0 0.46 9.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.6 EMC84333.1 - 0.035 13.5 0.0 0.72 9.2 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E CPT PF07931.7 EMC84333.1 - 0.079 12.5 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 EMC84333.1 - 0.082 12.9 0.2 13 5.8 0.0 3.3 3 1 0 3 3 2 0 Sigma-54 interaction domain DUF4582 PF15189.1 EMC84334.1 - 7.6e-27 93.6 0.0 5.8e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4582) DUF4582 PF15189.1 EMC84335.1 - 3.6e-31 107.7 0.7 3.9e-31 107.5 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4582) DicB PF05358.6 EMC84336.1 - 0.038 13.4 2.1 0.07 12.6 0.1 2.4 3 0 0 3 3 3 0 DicB protein OmpH PF03938.9 EMC84336.1 - 4.4 7.2 26.7 0.86 9.5 3.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) zf-DBF PF07535.7 EMC84337.1 - 6.3e-18 64.1 0.3 1e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 DBF zinc finger RNA_pol_Rpc82 PF05645.8 EMC84337.1 - 0.56 9.7 3.5 0.35 10.3 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 PilP PF04351.8 EMC84337.1 - 4.9 7.0 5.6 0.82 9.5 0.3 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilP Reprolysin PF01421.14 EMC84338.1 - 5.3e-60 202.4 0.0 1.1e-59 201.4 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EMC84338.1 - 2e-24 85.8 1.5 4.2e-24 84.8 1.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.7 EMC84338.1 - 7.1e-23 80.8 3.1 7.1e-23 80.8 2.2 3.7 3 1 0 4 4 4 1 ADAM cysteine-rich Disintegrin PF00200.18 EMC84338.1 - 2e-18 66.3 29.0 2e-18 66.3 20.1 3.4 4 0 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 EMC84338.1 - 1.5e-10 41.6 0.0 3.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC84338.1 - 6.3e-10 39.2 0.1 1.4e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMC84338.1 - 4.3e-07 30.1 0.1 1e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC84338.1 - 1.2e-05 24.9 0.1 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 EMC84338.1 - 0.00032 20.8 10.5 0.00032 20.8 7.3 7.0 6 2 1 7 7 7 1 EGF-like domain hEGF PF12661.2 EMC84338.1 - 0.036 14.1 0.7 0.036 14.1 0.5 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF GTP_EFTU PF00009.22 EMC84339.1 - 4.7e-43 146.8 0.0 7e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMC84339.1 - 1.1e-26 92.6 0.0 2.5e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMC84339.1 - 1.1e-21 76.4 0.0 3e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC84339.1 - 1.9e-11 43.9 0.1 5.2e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMC84339.1 - 2e-08 33.9 0.0 5.3e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EMC84339.1 - 4.1e-05 24.0 0.0 8.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EMC84339.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin Nop14 PF04147.7 EMC84339.1 - 6 4.6 6.9 8.7 4.1 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family V-set PF07686.12 EMC84341.1 - 5.4e-11 42.3 0.0 7.2e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 EMC84341.1 - 3.1e-06 27.2 0.4 0.091 12.8 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC84341.1 - 2.8e-05 24.1 0.0 0.044 13.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC84341.1 - 4.8e-05 23.1 0.0 0.073 12.9 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Receptor_2B4 PF11465.3 EMC84341.1 - 0.047 13.5 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Filament PF00038.16 EMC84342.1 - 3.2e-81 273.1 26.0 1.3e-49 169.3 2.9 2.8 1 1 1 2 2 2 2 Intermediate filament protein Filament_head PF04732.9 EMC84342.1 - 1.2e-06 29.1 0.1 6.1e-05 23.6 0.0 2.8 3 0 0 3 3 3 1 Intermediate filament head (DNA binding) region P22_AR_C PF10548.4 EMC84342.1 - 0.033 14.0 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 P22AR C-terminal domain ApoO PF09769.4 EMC84342.1 - 0.045 13.4 2.4 0.41 10.3 0.0 3.2 3 1 1 4 4 4 0 Apolipoprotein O TPR_MLP1_2 PF07926.7 EMC84342.1 - 0.34 10.6 23.3 0.13 11.9 0.9 4.4 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein ACCA PF03255.9 EMC84342.1 - 1.3 8.5 9.0 1.5 8.3 0.1 3.1 3 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1192 PF06698.6 EMC84342.1 - 2.3 8.0 12.4 0.26 11.1 1.4 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) AAA_13 PF13166.1 EMC84342.1 - 9.8 4.4 16.2 0.2 10.1 5.6 1.8 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.18 EMC84343.1 - 2.5e-107 358.4 0.0 3.1e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Exotox-A_target PF09102.5 EMC84343.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Exotoxin A, targeting C1q PF00386.16 EMC84344.1 - 3.6e-35 120.7 0.2 4.2e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 EMC84344.1 - 0.027 14.0 0.1 0.17 11.4 0.0 1.9 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 EMC84344.1 - 0.068 12.7 5.9 0.13 11.8 4.1 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Collagen PF01391.13 EMC84345.1 - 4.3e-16 58.2 76.5 1.6 8.3 18.8 3.6 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) GTP_EFTU_D3 PF03143.12 EMC84347.1 - 7.7e-09 35.6 0.0 8.2e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain FBPase PF00316.15 EMC84349.1 - 1.9e-130 434.4 0.0 2.2e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EMC84349.1 - 7.1e-05 22.2 0.0 0.00015 21.1 0.0 1.5 2 0 0 2 2 2 1 Inositol monophosphatase family ABC2_membrane PF01061.19 EMC84349.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 ABC-2 type transporter DUF159 PF02586.9 EMC84349.1 - 0.042 13.3 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, COG2135 Peptidase_C1 PF00112.18 EMC84350.1 - 5.4e-90 301.0 2.7 8e-90 300.5 1.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EMC84350.1 - 6.8e-14 51.8 2.2 1.4e-13 50.8 1.5 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EMC84350.1 - 4.2e-06 25.5 2.8 0.00031 19.3 0.8 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Ank_2 PF12796.2 EMC84351.1 - 5.9e-75 247.6 12.8 6.2e-25 87.3 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 EMC84351.1 - 3.9e-68 229.4 0.0 6.6e-68 228.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.25 EMC84351.1 - 6.5e-65 211.8 8.1 2.1e-08 33.5 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 EMC84351.1 - 3e-50 167.7 5.7 4.9e-11 42.8 0.0 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC84351.1 - 1.8e-47 158.2 12.8 1.1e-09 38.2 0.0 7.7 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84351.1 - 5.1e-47 153.1 8.1 3.1e-06 26.9 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Pkinase_Tyr PF07714.12 EMC84351.1 - 3.3e-34 118.1 0.0 6.1e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC84351.1 - 7.1e-06 25.2 0.0 1.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC84351.1 - 8.5e-05 21.9 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EMC84351.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glycos_trans_3N PF02885.12 EMC84351.1 - 0.039 13.5 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain APH PF01636.18 EMC84351.1 - 0.085 12.5 0.1 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family PAP_assoc PF03828.14 EMC84353.1 - 8.8e-28 96.0 2.3 1.3e-14 53.9 0.2 3.1 3 0 0 3 3 3 2 Cid1 family poly A polymerase zf-CCHC PF00098.18 EMC84353.1 - 1.4e-15 56.3 22.3 2.7e-05 23.8 2.3 3.8 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 EMC84353.1 - 1.7e-07 30.6 17.0 0.0062 16.0 0.8 4.7 4 0 0 4 4 4 3 Zinc knuckle NTP_transf_2 PF01909.18 EMC84353.1 - 5.6e-05 23.4 0.0 0.0016 18.7 0.0 2.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC_4 PF14392.1 EMC84353.1 - 0.00026 20.5 19.0 0.012 15.3 1.1 3.9 3 0 0 3 3 3 3 Zinc knuckle tRNA_NucTransf2 PF09249.6 EMC84353.1 - 0.00062 19.6 0.0 1.9 8.3 0.0 2.9 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain zf-C2H2_jaz PF12171.3 EMC84353.1 - 0.017 15.2 3.1 0.07 13.3 2.2 2.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Succ_CoA_lig PF13607.1 EMC84353.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain zf-C2H2_2 PF12756.2 EMC84353.1 - 0.19 11.8 6.7 0.1 12.7 0.7 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Fe-S_biosyn PF01521.15 EMC84354.1 - 1.5e-18 66.7 0.0 1.6e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis IncA PF04156.9 EMC84355.1 - 0.0013 18.3 14.9 0.0013 18.3 10.4 3.5 2 1 1 3 3 3 2 IncA protein DLH PF01738.13 EMC84355.1 - 0.072 12.3 0.2 0.16 11.2 0.1 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF1471 PF07338.8 EMC84355.1 - 0.098 12.3 0.1 0.91 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Mak10 PF04112.8 EMC84356.1 - 3.1e-51 172.9 0.2 7.8e-51 171.6 0.1 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Rer1 PF03248.8 EMC84356.1 - 0.0013 18.3 1.0 0.0024 17.5 0.7 1.4 1 0 0 1 1 1 1 Rer1 family Peptidase_M14 PF00246.19 EMC84357.1 - 3.2e-26 92.5 0.0 8.9e-26 91.1 0.0 1.7 1 1 1 2 2 2 1 Zinc carboxypeptidase V-ATPase_H_N PF03224.9 EMC84357.1 - 1.2e-05 24.5 1.9 3.2e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 V-ATPase subunit H AstE_AspA PF04952.9 EMC84357.1 - 0.0055 15.6 0.0 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase_Tyr PF07714.12 EMC84358.1 - 7e-98 326.8 0.0 9.4e-98 326.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC84358.1 - 4.1e-50 170.3 0.0 5.9e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 EMC84358.1 - 1.5e-22 79.2 0.5 2.7e-12 46.3 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84358.1 - 1.8e-09 37.5 1.8 3.5e-05 23.8 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC84358.1 - 6.1e-09 36.2 8.3 5.7e-08 33.1 2.5 2.8 2 0 0 2 2 2 1 Immunoglobulin domain LRR_8 PF13855.1 EMC84358.1 - 5.3e-08 32.4 0.5 1.5e-07 31.0 0.4 1.8 1 0 0 1 1 1 1 Leucine rich repeat ig PF00047.20 EMC84358.1 - 5.6e-07 29.5 5.8 3.7e-05 23.7 0.3 2.9 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC84358.1 - 0.0021 17.9 0.7 0.78 9.6 0.1 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC84358.1 - 0.0043 16.9 0.2 0.085 12.7 0.1 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kinase-like PF14531.1 EMC84358.1 - 0.0072 15.3 0.1 0.022 13.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like LRR_1 PF00560.28 EMC84358.1 - 0.02 14.8 3.1 0.041 13.9 0.4 3.0 3 0 0 3 3 1 0 Leucine Rich Repeat LRR_4 PF12799.2 EMC84358.1 - 0.03 13.9 1.9 0.062 12.9 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Herpes_gE PF02480.11 EMC84358.1 - 0.054 11.7 0.0 3.6 5.7 0.0 2.8 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E RNA_pol_Rpb2_2 PF04561.9 EMC84359.1 - 0.0011 18.3 0.1 0.0033 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 TPR_19 PF14559.1 EMC84359.1 - 0.0027 17.9 0.6 0.021 15.1 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF356 PF04009.7 EMC84359.1 - 0.042 13.9 0.3 0.72 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF356) Pkinase PF00069.20 EMC84360.1 - 4.6e-46 157.0 0.0 6.7e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EMC84360.1 - 6.9e-45 152.0 0.3 1.2e-44 151.2 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EMC84360.1 - 1.2e-25 90.0 0.0 1.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 EMC84360.1 - 1.6e-07 31.0 0.0 0.011 15.1 0.0 2.5 1 1 0 2 2 2 2 PQQ-like domain APH PF01636.18 EMC84360.1 - 2.6e-05 24.0 0.2 0.09 12.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family PQQ PF01011.16 EMC84360.1 - 5.1e-05 22.5 0.6 0.032 13.7 0.0 3.5 5 0 0 5 5 5 1 PQQ enzyme repeat Kdo PF06293.9 EMC84360.1 - 0.0037 16.3 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC84360.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Prion_bPrPp PF11587.3 EMC84360.1 - 0.18 11.4 0.2 0.71 9.5 0.1 2.0 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal PQQ_3 PF13570.1 EMC84360.1 - 0.26 11.6 1.2 5.6 7.3 0.0 3.7 4 1 0 4 4 4 0 PQQ-like domain DUF2404 PF10296.4 EMC84361.1 - 7.3e-27 93.3 1.6 6.7e-26 90.2 0.0 2.7 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) Ig_2 PF13895.1 EMC84362.1 - 3.8e-46 155.1 1.8 2.1e-11 43.7 0.0 6.2 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 EMC84362.1 - 8.6e-17 61.3 4.0 0.00067 20.1 0.0 7.1 6 2 0 6 6 6 4 Immunoglobulin domain I-set PF07679.11 EMC84362.1 - 5.5e-15 54.9 13.7 0.0081 15.9 0.1 7.6 6 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.12 EMC84362.1 - 6.6e-13 48.5 4.5 0.13 12.1 0.0 6.8 6 1 0 6 6 6 4 Immunoglobulin V-set domain ig PF00047.20 EMC84362.1 - 3.9e-12 46.1 2.6 0.096 12.8 0.0 6.9 6 2 0 6 6 6 4 Immunoglobulin domain C2-set PF05790.10 EMC84362.1 - 0.0044 16.9 4.0 1.6 8.7 0.0 4.8 4 0 0 4 4 4 1 Immunoglobulin C2-set domain V-set_CD47 PF08204.6 EMC84362.1 - 0.043 13.5 1.1 1.4 8.7 0.1 3.5 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain Ig_2 PF13895.1 EMC84363.1 - 1.6e-09 37.7 0.1 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84363.1 - 5.8e-05 23.5 0.2 0.00015 22.2 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC84363.1 - 0.00084 19.4 0.0 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 EMC84363.1 - 0.0017 18.2 0.0 0.0045 16.8 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.12 EMC84363.1 - 0.011 15.6 0.9 0.29 11.0 0.6 2.4 1 1 0 1 1 1 0 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC84363.1 - 0.098 12.5 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain HGTP_anticodon PF03129.15 EMC84364.1 - 1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EMC84364.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) DEAD PF00270.24 EMC84365.1 - 1.9e-42 144.6 0.0 1.4e-41 141.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase P68HR PF08061.6 EMC84365.1 - 2.3e-28 97.6 18.3 2.7e-15 55.8 2.7 2.6 2 0 0 2 2 2 2 P68HR (NUC004) repeat Helicase_C PF00271.26 EMC84365.1 - 1.7e-26 91.8 0.0 8.8e-26 89.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC84365.1 - 0.00048 20.0 0.0 0.019 14.7 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EMC84365.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain HECT PF00632.20 EMC84366.1 - 7.1e-101 337.5 0.0 9.9e-101 337.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMC84366.1 - 2.8e-29 100.6 10.9 1.3e-10 40.9 0.2 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EMC84366.1 - 1.1e-14 54.0 0.1 2.1e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 C2 domain Arm PF00514.18 EMC84367.1 - 2e-80 262.1 9.8 9.1e-12 44.3 0.0 8.8 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC84367.1 - 1.3e-16 60.6 0.2 0.00042 20.5 0.0 6.0 1 1 2 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EMC84367.1 - 6e-15 55.2 0.3 6e-05 23.3 0.0 5.5 3 1 3 6 6 6 3 HEAT-like repeat HEAT PF02985.17 EMC84367.1 - 7e-08 31.9 4.7 0.048 13.7 0.0 6.1 9 0 0 9 9 9 2 HEAT repeat KAP PF05804.7 EMC84367.1 - 0.0014 16.6 0.1 0.13 10.2 0.1 2.6 2 1 1 3 3 3 2 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.3 EMC84367.1 - 0.036 13.9 1.4 8.3 6.3 0.1 3.4 3 1 1 4 4 4 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 EMC84367.1 - 0.036 12.3 0.5 1.4 7.0 0.1 3.3 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 EMC84367.1 - 0.21 10.2 2.0 0.58 8.8 0.0 2.2 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Endonuclease_NS PF01223.18 EMC84368.1 - 7.8e-25 87.7 0.2 9e-25 87.5 0.2 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 EMC84368.1 - 0.0024 17.8 1.9 0.0046 16.9 1.3 1.6 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2540 PF10802.3 EMC84368.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) MFS_2 PF13347.1 EMC84370.1 - 8.7e-26 90.2 9.1 2.1e-25 89.0 6.3 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein Actin PF00022.14 EMC84371.1 - 1.2e-131 438.7 0.0 1.4e-131 438.5 0.0 1.0 1 0 0 1 1 1 1 Actin SUFU_C PF12470.3 EMC84372.1 - 1.5e-95 318.6 0.0 1.9e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.8 EMC84372.1 - 1.4e-35 122.3 0.0 2.1e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) zf-C3HC4_4 PF15227.1 EMC84373.1 - 3.6e-11 42.7 8.3 3.6e-11 42.7 5.7 3.3 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMC84373.1 - 1.2e-09 37.6 6.5 1.2e-09 37.6 4.5 2.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84373.1 - 1.4e-07 31.4 8.9 1.4e-07 31.4 6.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC84373.1 - 9.4e-07 28.5 8.1 9.4e-07 28.5 5.6 3.3 3 0 0 3 3 2 1 Ring finger domain CASP_C PF08172.7 EMC84373.1 - 1.7e-05 24.0 2.6 3.1e-05 23.1 1.8 1.5 1 0 0 1 1 1 1 CASP C terminal zf-RING_UBOX PF13445.1 EMC84373.1 - 2.7e-05 23.7 4.6 2.7e-05 23.7 3.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.19 EMC84373.1 - 0.00026 20.7 7.7 0.00026 20.7 5.3 5.2 5 1 0 5 5 4 1 B-box zinc finger zf-RING_5 PF14634.1 EMC84373.1 - 0.00086 18.9 6.6 0.00086 18.9 4.6 3.9 3 2 1 4 4 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 EMC84373.1 - 0.018 14.8 3.5 0.067 12.9 2.4 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.10 EMC84373.1 - 0.095 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain IncA PF04156.9 EMC84373.1 - 0.57 9.7 11.6 1.1 8.8 8.0 1.4 1 0 0 1 1 1 0 IncA protein Phasin PF05597.6 EMC84373.1 - 0.61 9.8 8.4 1.1 9.0 5.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) APG6 PF04111.7 EMC84373.1 - 1.5 7.8 12.6 2.3 7.1 8.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EMC84373.1 - 4.1 5.7 9.8 5.9 5.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Arf PF00025.16 EMC84374.1 - 4e-72 241.0 0.0 4.5e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC84374.1 - 1.4e-14 53.6 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC84374.1 - 4.9e-14 51.8 0.8 2.2e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMC84374.1 - 1.6e-13 50.3 0.0 1.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC84374.1 - 2.3e-13 49.8 0.0 2.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC84374.1 - 5.7e-12 46.1 0.0 7.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC84374.1 - 9.9e-10 38.3 0.0 1.3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC84374.1 - 4.2e-07 29.5 0.0 8.2e-05 22.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.24 EMC84374.1 - 0.00011 22.3 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EMC84374.1 - 0.00095 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EMC84374.1 - 0.0047 17.7 0.1 0.039 14.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EMC84374.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMC84374.1 - 0.016 15.3 0.1 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMC84374.1 - 0.025 14.2 0.0 6 6.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EMC84374.1 - 0.029 14.6 0.1 0.045 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EMC84374.1 - 0.03 14.1 0.0 0.52 10.1 0.0 2.1 1 1 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 EMC84374.1 - 0.036 13.7 0.1 0.044 13.4 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 EMC84374.1 - 0.062 12.5 0.1 0.18 11.0 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ArgK PF03308.11 EMC84374.1 - 0.068 11.9 0.1 6.9 5.3 0.0 2.7 2 1 0 2 2 2 0 ArgK protein cobW PF02492.14 EMC84374.1 - 0.076 12.4 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EMC84374.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.1 EMC84374.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC84374.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Mtc PF03820.12 EMC84375.1 - 2.7e-127 423.6 0.1 3e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WBP-1 PF11669.3 EMC84376.1 - 3.7e-50 168.2 13.6 5.8e-50 167.6 9.4 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 p450 PF00067.17 EMC84377.1 - 1.7e-81 274.1 0.0 1.9e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC84378.1 - 6.7e-31 107.3 0.0 8.3e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 EMC84379.1 - 1.4e-33 115.6 0.0 2.5e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC84379.1 - 2.3e-18 66.4 0.0 6e-18 65.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC84379.1 - 1.6e-14 53.5 0.0 2.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMC84379.1 - 3.5e-14 53.3 0.0 1.8e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC84379.1 - 2.6e-13 50.0 0.0 3.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC84379.1 - 5.5e-13 49.1 0.0 5.5e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84379.1 - 1.1e-12 48.3 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC84379.1 - 5.2e-09 36.1 0.0 1.7e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EMC84379.1 - 2.7e-06 27.0 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 EMC84379.1 - 2.2e-05 24.1 0.0 6.9e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 Hypothetical methyltransferase MTS PF05175.9 EMC84379.1 - 0.00052 19.4 0.0 0.0015 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EMC84379.1 - 0.0053 15.9 0.1 0.013 14.6 0.1 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EMC84379.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EMC84379.1 - 0.06 12.7 0.3 0.32 10.3 0.2 1.9 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DUF21 PF01595.15 EMC84380.1 - 7e-31 106.9 0.0 1.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EMC84380.1 - 5.7e-08 32.4 0.1 0.00053 19.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 EMC84380.1 - 2.4e-05 24.0 0.0 0.011 15.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Nrf1_DNA-bind PF10491.4 EMC84380.1 - 0.098 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 5_nucleotid PF05761.9 EMC84381.1 - 2.3e-182 606.5 0.2 2.7e-182 606.2 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family WD40 PF00400.27 EMC84382.1 - 5e-71 232.2 8.0 3.6e-13 48.8 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EMC84382.1 - 2.6e-42 144.2 6.2 4.2e-42 143.6 4.3 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EMC84382.1 - 3.8e-09 35.2 1.3 0.013 13.6 0.0 3.8 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EMC84382.1 - 0.0065 16.2 0.0 0.038 13.6 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMC84382.1 - 0.034 12.4 0.0 1.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF4144 PF13642.1 EMC84382.1 - 0.23 11.8 1.0 0.5 10.7 0.7 1.5 1 0 0 1 1 1 0 protein structure with unknown function ATP_synth_reg PF14960.1 EMC84383.1 - 1.3e-25 88.3 0.3 1.4e-25 88.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase regulation DUF4345 PF14248.1 EMC84383.1 - 0.089 12.2 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) TPR_19 PF14559.1 EMC84384.1 - 6.8e-13 48.7 0.0 4.5e-06 26.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC84384.1 - 2.7e-12 47.0 0.0 3e-05 24.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 EMC84384.1 - 3.5e-12 46.6 20.7 1.8e-08 34.4 0.5 4.1 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMC84384.1 - 1.1e-10 41.1 1.4 0.084 13.5 0.1 4.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EMC84384.1 - 7.4e-09 35.0 6.0 0.00038 19.6 0.7 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC84384.1 - 3.8e-07 29.6 0.1 0.0065 16.1 0.3 3.4 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 EMC84384.1 - 9.4e-05 22.2 5.9 0.12 12.3 0.0 3.8 1 1 4 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC84384.1 - 0.0067 16.5 2.4 0.091 12.9 0.4 2.9 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Lig_chan PF00060.21 EMC84384.1 - 0.059 13.0 2.0 25 4.5 0.0 3.9 3 1 0 3 3 3 0 Ligand-gated ion channel DUF3366 PF11846.3 EMC84384.1 - 0.06 13.2 1.2 0.14 12.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) TPR_2 PF07719.12 EMC84384.1 - 0.082 12.8 8.0 1.5 8.8 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC84384.1 - 0.43 11.1 6.9 7.7 7.2 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC84384.1 - 3.1 7.8 7.9 0.75 9.7 0.2 4.0 5 2 1 6 6 5 0 Tetratricopeptide repeat Ca_hom_mod PF14798.1 EMC84385.1 - 1.4e-90 302.6 0.6 1.7e-90 302.3 0.4 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF996 PF06195.8 EMC84385.1 - 0.013 15.4 0.1 0.086 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF1218 PF06749.7 EMC84385.1 - 0.057 13.8 0.8 0.25 11.8 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Ca_hom_mod PF14798.1 EMC84386.1 - 1.9e-92 308.8 4.8 2.2e-92 308.6 3.3 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.1 EMC84387.1 - 1.8e-87 292.5 9.2 2e-87 292.3 6.3 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Neuralized PF07177.7 EMC84388.1 - 2.1e-48 162.0 0.2 1.1e-31 108.4 0.0 2.5 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.1 EMC84388.1 - 1.5e-12 46.9 13.0 1.5e-12 46.9 9.0 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84388.1 - 1.4e-06 28.1 16.6 1.4e-06 28.1 11.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.19 EMC84389.1 - 4.8e-17 61.7 0.1 5.4e-17 61.6 0.1 1.0 1 0 0 1 1 1 1 PX domain STN1_2 PF09170.5 EMC84390.1 - 6.1e-60 201.9 0.5 9.4e-60 201.3 0.4 1.3 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.20 EMC84390.1 - 3.9e-10 39.4 0.2 7.8e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.4 EMC84390.1 - 3.9e-08 32.4 1.0 4.3e-07 29.0 0.2 2.7 2 1 0 2 2 2 1 Telomere regulation protein Stn1 DUF3136 PF11334.3 EMC84390.1 - 0.13 11.6 0.1 0.49 9.8 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3136) Pkinase PF00069.20 EMC84391.1 - 1.9e-69 233.7 0.0 1.9e-69 233.7 0.0 4.3 4 1 0 4 4 4 1 Protein kinase domain PKK PF12474.3 EMC84391.1 - 2.2e-57 192.7 77.4 3.4e-44 150.0 29.1 8.9 6 2 3 9 9 9 3 Polo kinase kinase Pkinase_Tyr PF07714.12 EMC84391.1 - 4.8e-48 163.4 0.0 4.8e-48 163.4 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Mei5 PF10376.4 EMC84392.1 - 4.3e-35 121.2 13.7 1.1e-34 119.9 9.5 1.6 1 1 0 1 1 1 1 Double-strand recombination repair protein GST_N_3 PF13417.1 EMC84393.1 - 2.2e-24 85.4 0.0 5.2e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMC84393.1 - 3.6e-16 58.9 0.0 6.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC84393.1 - 1.3e-07 31.6 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC84393.1 - 3.7e-06 26.8 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC84393.1 - 0.00016 21.4 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EMC84393.1 - 0.00033 20.5 0.0 0.00085 19.2 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.1 EMC84393.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PKD PF00801.15 EMC84394.1 - 8.8e-12 44.6 1.5 9.7e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 PKD domain BNR PF02012.15 EMC84394.1 - 0.13 12.1 23.3 2.6 8.2 0.3 6.6 7 0 0 7 7 7 0 BNR/Asp-box repeat PKD PF00801.15 EMC84395.1 - 8.8e-10 38.2 1.9 1.9e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 PKD domain BNR PF02012.15 EMC84395.1 - 0.0003 20.1 11.8 1.4 9.0 0.4 5.7 5 0 0 5 5 5 2 BNR/Asp-box repeat BNR_2 PF13088.1 EMC84395.1 - 0.03 13.5 0.0 2.2 7.5 0.0 3.1 2 1 0 2 2 2 0 BNR repeat-like domain Peptidase_M24 PF00557.19 EMC84396.1 - 8.3e-43 146.3 0.0 1.2e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMC84396.1 - 1.6e-18 67.4 0.0 9.4e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Aldolase_II PF00596.16 EMC84397.1 - 1.3e-37 129.1 0.1 2.1e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lge1 PF11488.3 EMC84397.1 - 0.0034 17.5 0.3 0.6 10.3 0.1 2.9 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 DUF16 PF01519.11 EMC84397.1 - 0.038 14.1 2.7 0.13 12.4 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 HLH PF00010.21 EMC84398.1 - 2.9e-12 46.1 1.0 1.8e-10 40.3 0.7 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG6 PF04111.7 EMC84398.1 - 0.0067 15.5 2.9 0.008 15.2 2.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 EMC84398.1 - 0.041 13.4 2.7 0.05 13.1 1.9 1.2 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 EMC84398.1 - 0.044 13.0 0.1 0.052 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 EMC84398.1 - 0.32 10.5 3.3 0.7 9.4 2.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Uds1 PF15456.1 EMC84398.1 - 0.73 9.8 8.2 0.06 13.3 1.5 2.1 2 1 0 2 2 2 0 Up-regulated During Septation EMP24_GP25L PF01105.19 EMC84398.1 - 4.4 6.9 5.7 0.66 9.6 0.9 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SMN PF06003.7 EMC84399.1 - 1.5e-16 60.3 4.1 3e-16 59.3 2.7 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 EMC84399.1 - 0.0002 21.1 0.0 0.00072 19.3 0.0 2.0 1 1 1 2 2 2 1 Tudor domain DUF3703 PF12487.3 EMC84399.1 - 0.24 11.0 1.9 0.31 10.6 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3703) EAP30 PF04157.11 EMC84399.1 - 0.81 8.7 5.7 7.6 5.6 0.9 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family DSPc PF00782.15 EMC84400.1 - 4.1e-37 126.7 0.0 8.7e-37 125.6 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC84400.1 - 7.5e-06 25.4 0.0 9.9e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC84400.1 - 0.022 14.7 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 EMC84400.1 - 0.054 12.9 0.1 0.098 12.0 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF442 PF04273.8 EMC84400.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) SMC_N PF02463.14 EMC84401.1 - 3.6e-66 222.5 12.8 6.8e-66 221.6 8.9 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMC84401.1 - 7.6e-24 83.9 0.0 2.1e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMC84401.1 - 9.2e-11 42.2 21.2 4.9e-06 26.7 2.9 4.5 2 2 1 3 3 3 2 AAA domain AAA_23 PF13476.1 EMC84401.1 - 1.3e-07 32.2 48.7 1.3e-07 32.2 33.8 7.5 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 EMC84401.1 - 0.00053 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMC84401.1 - 0.22 10.9 0.0 0.22 10.9 0.0 3.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_13 PF13166.1 EMC84401.1 - 0.32 9.4 0.0 0.32 9.4 0.0 6.2 4 2 3 7 7 7 0 AAA domain Reo_sigmaC PF04582.7 EMC84401.1 - 0.42 9.7 22.4 0.97 8.5 1.5 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein RRM_5 PF13893.1 EMC84402.1 - 2.2e-09 37.0 0.0 3.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EMC84402.1 - 1.4e-07 31.4 5.3 0.00093 19.2 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding RRM_6 PF14259.1 EMC84402.1 - 1.9e-07 30.9 0.0 3.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.2 EMC84402.1 - 0.049 13.8 8.0 0.46 10.7 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-U1 PF06220.7 EMC84402.1 - 0.098 12.2 2.6 0.26 10.8 1.8 1.7 1 0 0 1 1 1 0 U1 zinc finger RRM_1 PF00076.17 EMC84402.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 EMC84402.1 - 0.74 10.2 5.6 5 7.6 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4199 PF13858.1 EMC84402.1 - 0.79 9.6 0.3 1.8 8.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TSC22 PF01166.13 EMC84403.1 - 2.1e-29 101.2 1.7 4.7e-29 100.1 1.2 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 EMC84403.1 - 0.0021 18.3 0.7 0.0086 16.4 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF972) DivIC PF04977.10 EMC84403.1 - 0.05 13.0 1.9 0.1 12.0 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 EMC84403.1 - 3.4 8.0 8.7 9 6.6 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DNA_methylase PF00145.12 EMC84405.1 - 3.1e-36 125.1 0.0 4.9e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Glyco_transf_29 PF00777.13 EMC84407.1 - 3.6e-76 255.8 0.0 5.3e-76 255.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) VHS PF00790.14 EMC84409.1 - 2.9e-44 150.1 1.7 4e-44 149.6 0.1 2.0 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 EMC84409.1 - 3.1e-16 58.4 0.1 5.9e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC84409.1 - 2.6e-13 49.2 0.0 4.6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC84409.1 - 2.7e-12 45.9 0.0 4.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EMC84409.1 - 0.00021 20.5 0.6 0.00065 19.0 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif HEAT_2 PF13646.1 EMC84409.1 - 0.05 13.8 0.1 0.61 10.3 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.17 EMC84409.1 - 0.25 11.5 1.3 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat Lectin_C PF00059.16 EMC84410.1 - 4.3e-152 496.5 46.0 4.7e-23 81.8 0.2 9.1 9 0 0 9 9 9 8 Lectin C-type domain Herpes_UL45 PF05473.7 EMC84410.1 - 3.7e-15 55.8 2.4 1.9e-05 24.2 0.0 5.5 5 0 0 5 5 5 3 UL45 protein fn2 PF00040.14 EMC84410.1 - 5.2e-14 51.9 8.4 5.2e-14 51.9 5.8 2.5 2 0 0 2 2 2 1 Fibronectin type II domain Ricin_B_lectin PF00652.17 EMC84410.1 - 2e-07 31.0 0.3 5e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.7 EMC84410.1 - 2.5e-06 26.4 9.9 0.003 16.3 0.0 5.6 6 0 0 6 6 6 3 Chordopoxvirus A33R protein Lectin_C PF00059.16 EMC84411.1 - 8.6e-68 225.6 13.8 1.5e-22 80.2 0.2 6.4 5 1 0 5 5 5 4 Lectin C-type domain fn2 PF00040.14 EMC84411.1 - 2.5e-11 43.3 6.2 2.5e-11 43.3 4.3 2.5 2 0 0 2 2 2 1 Fibronectin type II domain Herpes_UL45 PF05473.7 EMC84411.1 - 1.6e-10 40.7 2.1 0.00041 19.8 0.0 4.3 2 1 2 4 4 4 2 UL45 protein Ricin_B_lectin PF00652.17 EMC84411.1 - 2.1e-09 37.4 0.9 4.6e-09 36.3 0.6 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Xlink PF00193.12 EMC84411.1 - 6.1e-07 29.4 0.2 0.69 10.0 0.0 4.0 4 0 0 4 4 4 3 Extracellular link domain Chordopox_A33R PF05966.7 EMC84411.1 - 3.4e-06 25.9 4.0 0.03 13.1 0.1 3.7 4 0 0 4 4 4 2 Chordopoxvirus A33R protein Intimin_C PF07979.6 EMC84411.1 - 0.039 14.1 0.1 27 5.0 0.0 3.6 4 0 0 4 4 4 0 Intimin C-type lectin domain Lectin_C PF00059.16 EMC84412.1 - 3.5e-15 56.5 0.1 6.1e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain MHC2-interact PF09307.5 EMC84412.1 - 0.0044 16.7 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 CLIP, MHC2 interacting DUF4366 PF14283.1 EMC84412.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.6 EMC84412.1 - 0.065 12.4 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lectin_C PF00059.16 EMC84413.1 - 2.3e-05 24.9 4.7 0.002 18.7 2.9 4.3 2 1 0 2 2 2 1 Lectin C-type domain Motile_Sperm PF00635.21 EMC84414.1 - 1.9e-32 111.1 0.6 3.1e-32 110.4 0.4 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain bZIP_1 PF00170.16 EMC84414.1 - 0.0052 16.7 0.5 0.0091 15.9 0.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor Rab5-bind PF09311.6 EMC84414.1 - 0.023 14.5 1.6 0.046 13.6 0.7 1.6 2 0 0 2 2 2 0 Rabaptin-like protein DUF972 PF06156.8 EMC84414.1 - 0.026 14.8 0.1 0.05 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC155 PF14662.1 EMC84414.1 - 0.058 12.9 0.2 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF904 PF06005.7 EMC84414.1 - 0.11 12.7 0.2 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Ras PF00071.17 EMC84415.1 - 5.6e-38 129.8 0.0 7.3e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC84415.1 - 2.6e-09 37.6 0.0 6.3e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC84415.1 - 0.00016 20.9 0.0 0.00096 18.4 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Tsg PF04668.7 EMC84416.1 - 1.6e-56 190.1 7.4 1.6e-56 190.1 5.1 2.3 2 1 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region Ank PF00023.25 EMC84417.1 - 1.7e-27 93.8 0.1 1.4e-08 34.1 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EMC84417.1 - 2.4e-23 82.2 0.1 4.2e-16 59.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC84417.1 - 1.5e-19 69.5 0.1 1.6e-08 34.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84417.1 - 1.6e-17 61.8 0.0 0.00011 22.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMC84417.1 - 6.9e-15 55.0 0.0 1.2e-07 32.0 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (many copies) 2Fe-2S_thioredx PF01257.14 EMC84418.1 - 4.9e-66 220.7 0.1 6e-66 220.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 EMC84418.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) DUF3166 PF11365.3 EMC84419.1 - 6.7e-58 193.1 35.0 2.4e-41 140.1 1.5 5.7 5 1 0 5 5 5 3 Protein of unknown function (DUF3166) DUF4482 PF14818.1 EMC84419.1 - 1.4e-45 155.4 9.4 1.4e-45 155.4 6.5 7.4 7 2 1 8 8 8 1 Domain of unknown function (DUF4482) Fes1 PF08609.5 EMC84419.1 - 0.13 12.7 7.1 9.2 6.8 1.5 4.3 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 TSC22 PF01166.13 EMC84419.1 - 2.4 8.1 47.7 0.073 13.0 0.2 7.6 7 0 0 7 7 7 0 TSC-22/dip/bun family Ras PF00071.17 EMC84420.1 - 9.1e-46 155.1 0.2 1e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC84420.1 - 2.8e-12 47.1 0.0 4.7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC84420.1 - 2.3e-11 43.2 0.3 2.9e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC84420.1 - 3.4e-06 26.6 0.0 4.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC84420.1 - 0.00035 19.7 0.1 0.00041 19.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region YTH PF04146.10 EMC84420.1 - 0.038 13.5 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain Y_phosphatase PF00102.22 EMC84421.1 - 6.2e-154 510.1 0.1 2.1e-86 289.1 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase MAM PF00629.18 EMC84421.1 - 9.8e-25 87.1 0.0 4.7e-24 84.9 0.0 2.2 2 0 0 2 2 2 1 MAM domain fn3 PF00041.16 EMC84421.1 - 1.3e-24 86.1 13.8 9.5e-10 38.4 0.0 5.8 6 0 0 6 6 6 3 Fibronectin type III domain DSPc PF00782.15 EMC84421.1 - 4.5e-09 36.0 0.1 0.0019 17.7 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ig_2 PF13895.1 EMC84421.1 - 2e-05 24.6 0.0 5.5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain PTPlike_phytase PF14566.1 EMC84421.1 - 3.2e-05 24.0 0.0 0.017 15.1 0.0 2.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC84421.1 - 5.4e-05 23.5 0.0 0.036 14.3 0.0 2.7 2 0 0 2 2 2 1 Tyrosine phosphatase family I-set PF07679.11 EMC84421.1 - 0.00024 20.8 0.0 0.00061 19.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC84421.1 - 0.00036 20.5 0.0 0.0073 16.4 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84421.1 - 0.00042 20.7 0.0 0.0027 18.1 0.0 2.5 1 0 0 1 1 1 1 Immunoglobulin domain PepSY_TM_3 PF13706.1 EMC84421.1 - 0.016 14.5 0.6 0.035 13.5 0.3 1.7 2 0 0 2 2 2 0 PepSY-associated TM helix TMEM154 PF15102.1 EMC84421.1 - 0.075 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DctM PF06808.7 EMC84421.1 - 0.081 11.4 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 DctM-like transporters LRR_4 PF12799.2 EMC84422.1 - 5.6e-24 83.3 26.3 4.7e-08 32.4 2.6 5.4 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC84422.1 - 1.4e-20 72.8 25.5 8.5e-08 31.8 1.3 4.4 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EMC84422.1 - 2.5e-16 57.1 35.2 0.016 15.1 0.0 9.3 9 0 0 9 9 9 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC84422.1 - 2.3e-10 38.9 25.3 0.11 12.7 0.2 9.2 9 0 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 EMC84422.1 - 0.045 13.8 28.2 0.84 9.8 0.1 7.7 7 1 2 9 9 9 0 Leucine Rich repeat LRR_5 PF13306.1 EMC84422.1 - 0.14 11.8 1.5 0.23 11.1 1.0 1.2 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) DUF2371 PF10177.4 EMC84423.1 - 1.6e-56 190.1 0.0 3.2e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.1 EMC84423.1 - 0.13 11.6 0.0 0.38 10.1 0.0 1.7 1 0 0 1 1 1 0 Neurensin AKAP7_NLS PF10469.4 EMC84424.1 - 1.2e-44 152.5 0.7 1.4e-44 152.3 0.5 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EMC84424.1 - 5.3e-06 26.2 0.0 6.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 EMC84424.1 - 0.0022 17.9 0.1 0.26 11.2 0.0 2.5 2 1 0 2 2 2 1 LigT like Phosphoesterase HVSL PF09749.4 EMC84424.1 - 0.12 11.3 0.1 0.84 8.6 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised conserved protein FinO_N PF12602.3 EMC84427.1 - 1.3 9.3 6.1 2.2 8.6 1.1 2.1 2 0 0 2 2 2 0 Fertility inhibition protein N terminal DUF4124 PF13511.1 EMC84427.1 - 3.4 7.7 7.7 0.27 11.3 1.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4124) Fork_head PF00250.13 EMC84429.1 - 1.1e-07 31.7 0.3 1.9e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 Fork head domain DHHA2 PF02833.9 EMC84430.1 - 0.00068 19.8 0.1 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 DHHA2 domain FUR PF01475.14 EMC84430.1 - 0.0048 16.8 0.1 0.09 12.6 0.0 2.2 2 0 0 2 2 2 1 Ferric uptake regulator family CreA PF05981.7 EMC84430.1 - 0.052 13.0 0.1 0.79 9.2 0.0 2.4 2 1 0 2 2 2 0 CreA protein Ste50p-SAM PF09235.5 EMC84430.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif RPA_C PF08784.6 EMC84430.1 - 0.11 12.9 0.5 0.32 11.4 0.1 1.8 2 1 1 3 3 3 0 Replication protein A C terminal BNIP2 PF12496.3 EMC84431.1 - 2.4e-43 147.3 3.3 2.4e-43 147.3 2.3 8.6 9 3 0 9 9 9 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 EMC84431.1 - 1.5e-29 102.8 0.1 3.3e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EMC84431.1 - 1.4e-08 34.4 0.2 2.7e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Branch PF02485.16 EMC84432.1 - 2.1e-58 197.3 0.1 2.8e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme CD20 PF04103.10 EMC84433.1 - 3.6e-07 30.2 2.5 6.2e-07 29.4 1.7 1.4 1 0 0 1 1 1 1 CD20-like family PID PF00640.18 EMC84434.1 - 1.2e-50 171.1 0.8 2.4e-50 170.1 0.6 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 EMC84434.1 - 1e-31 108.9 10.3 5.1e-17 61.8 0.7 3.2 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC84434.1 - 1.3e-07 31.4 0.0 1.7e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 EMC84434.1 - 0.038 13.7 0.2 2.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Tricorn protease PDZ domain PPTA PF01239.17 EMC84435.1 - 2.8e-26 89.6 9.3 6.1e-09 34.8 0.1 5.4 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat MOZ_SAS PF01853.13 EMC84436.1 - 9e-07 28.3 0.1 1.9e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 MOZ/SAS family PRCC PF10253.4 EMC84437.1 - 3.2e-29 102.9 6.8 3.4e-29 102.8 4.7 1.0 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Tubulin PF00091.20 EMC84438.1 - 2.4e-12 47.1 0.0 2.9e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.20 EMC84439.1 - 4.2e-70 235.9 0.0 5.5e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC84439.1 - 2.3e-51 173.0 0.0 3.6e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC84439.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.12 EMC84440.1 - 1.5e-51 173.7 0.0 2.3e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 EMC84440.1 - 1.1e-43 149.5 0.0 5.9e-30 104.6 0.0 2.1 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Ras PF00071.17 EMC84441.1 - 7.5e-29 100.2 0.0 8.9e-29 99.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC84441.1 - 0.0015 19.0 0.0 0.0071 16.8 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein wnt PF00110.14 EMC84442.1 - 2e-111 372.1 0.6 2.2e-111 371.9 0.4 1.0 1 0 0 1 1 1 1 wnt family Arf PF00025.16 EMC84443.1 - 5.8e-79 263.3 0.1 7e-79 263.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC84443.1 - 5.2e-15 55.1 0.0 6.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMC84443.1 - 2.7e-13 49.6 0.0 3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC84443.1 - 1.6e-11 43.8 0.0 1.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC84443.1 - 4.6e-11 42.0 1.5 5.6e-08 31.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EMC84443.1 - 2.4e-09 37.6 0.0 3.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC84443.1 - 3.2e-06 27.0 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC84443.1 - 0.0011 18.4 0.1 0.0089 15.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EMC84443.1 - 0.0056 15.7 0.9 0.019 14.0 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EMC84443.1 - 0.064 13.1 0.2 0.13 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain FKBP_C PF00254.23 EMC84444.1 - 8.3e-21 73.8 0.0 1.1e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NYD-SP28_assoc PF14775.1 EMC84445.1 - 7.9e-07 28.6 4.2 1.2e-06 28.1 2.9 1.3 1 0 0 1 1 1 1 Sperm tail C-terminal domain DivIC PF04977.10 EMC84445.1 - 0.018 14.5 0.7 0.033 13.6 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Lant_dehyd_C PF04738.8 EMC84445.1 - 0.083 11.1 0.6 0.093 10.9 0.4 1.0 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus DEAD PF00270.24 EMC84446.1 - 2.1e-46 157.4 0.0 1.6e-45 154.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC84446.1 - 3.9e-17 61.8 0.0 1.8e-16 59.7 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Guanylate_kin PF00625.16 EMC84447.1 - 7.1e-28 97.2 0.2 1.5e-26 92.9 0.1 2.2 1 1 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.3 EMC84447.1 - 3.1e-11 42.9 4.1 5.3e-11 42.1 2.9 1.3 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal CENP-L PF13092.1 EMC84447.1 - 0.067 12.9 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DUF1053 PF06327.9 EMC84448.1 - 1.3e-20 73.6 1.0 1.9e-20 73.0 0.7 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Guanylate_cyc PF00211.15 EMC84448.1 - 4.1e-08 32.8 0.0 6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CobD_Cbib PF03186.8 EMC84448.1 - 0.68 8.9 3.7 6.3 5.7 0.2 2.2 1 1 1 2 2 2 0 CobD/Cbib protein PIG-P PF08510.7 EMC84448.1 - 1.8 8.1 5.3 2.3 7.8 0.9 2.3 2 0 0 2 2 2 0 PIG-P FA_desaturase PF00487.19 EMC84448.1 - 2.3 7.5 5.9 0.28 10.6 0.6 2.0 2 1 0 2 2 2 0 Fatty acid desaturase Cyclin_N PF00134.18 EMC84449.1 - 1.4e-16 60.1 0.8 2.3e-13 49.7 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain UPF0253 PF06786.7 EMC84449.1 - 0.08 13.0 0.2 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) Bax1-I PF01027.15 EMC84451.1 - 1.3e-22 80.4 13.5 9.3e-18 64.5 3.8 2.0 2 0 0 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 DUF1649 PF07855.7 EMC84452.1 - 5.3e-53 179.0 0.1 6.7e-53 178.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) tRNA_lig_CPD PF08302.6 EMC84452.1 - 0.023 13.8 0.9 0.83 8.8 0.0 2.4 3 0 0 3 3 3 0 Fungal tRNA ligase phosphodiesterase domain Pro_3_hydrox_C PF05373.6 EMC84452.1 - 0.072 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Pkinase PF00069.20 EMC84453.1 - 5.5e-52 176.4 0.0 7.8e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84453.1 - 6.8e-33 113.8 0.0 9.8e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 EMC84453.1 - 4e-15 54.8 0.2 7.9e-15 53.8 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 EMC84453.1 - 2.5e-14 53.6 8.5 5.7e-14 52.5 5.9 1.6 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.18 EMC84453.1 - 0.0059 16.3 0.0 0.02 14.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EMC84454.1 - 1e-41 142.8 0.0 1.3e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84454.1 - 1.8e-28 99.3 0.0 3.9e-28 98.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC84454.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_5 PF13857.1 EMC84456.1 - 2.2e-16 59.4 0.6 3.7e-08 33.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC84456.1 - 3.3e-15 56.2 0.1 1.1e-14 54.5 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC84456.1 - 1.6e-13 49.6 1.1 2.2e-06 27.1 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC84456.1 - 2.1e-12 47.1 0.3 8.3e-07 29.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84456.1 - 5.3e-12 44.7 0.3 1.2e-06 28.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Hexapep PF00132.19 EMC84458.1 - 2.3e-07 29.9 43.9 0.0055 16.1 3.7 6.1 2 1 3 6 6 6 6 Bacterial transferase hexapeptide (six repeats) TMEM213 PF15192.1 EMC84458.1 - 9.1 6.3 28.5 4.8e+02 0.8 6.6 5.0 1 1 1 2 2 2 0 TMEM213 family SLH PF00395.15 EMC84460.1 - 0.023 14.4 1.2 2.5 7.9 0.2 2.4 1 1 1 2 2 2 0 S-layer homology domain Plasmid_RAQPRD PF09686.5 EMC84460.1 - 0.05 13.6 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Pentapeptide PF00805.17 EMC84461.1 - 1.7e-05 23.9 7.7 8.5e-05 21.7 4.3 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EMC84461.1 - 0.056 13.2 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) SAM_PNT PF02198.11 EMC84461.1 - 0.18 11.6 1.3 2.8 7.7 0.1 2.1 1 1 1 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain PAN_4 PF14295.1 EMC84461.1 - 0.65 9.7 3.1 47 3.7 2.1 2.7 1 1 0 1 1 1 0 PAN domain Methyltransf_11 PF08241.7 EMC84462.1 - 8.3e-17 61.4 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC84462.1 - 4.4e-14 52.5 0.0 5.7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84462.1 - 2.9e-11 43.7 0.0 5.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC84462.1 - 7.7e-10 38.5 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC84462.1 - 7.8e-09 34.9 0.0 9.7e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMC84462.1 - 7.1e-07 29.5 0.0 2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC84462.1 - 8.3e-06 26.3 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC84462.1 - 2.5e-05 24.2 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMC84462.1 - 0.00049 19.8 0.0 0.00078 19.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 EMC84462.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EMC84462.1 - 0.089 13.6 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Trypsin PF00089.21 EMC84463.1 - 7.9e-54 182.5 0.0 8.7e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin bZIP_1 PF00170.16 EMC84464.1 - 2.2e-22 78.7 8.7 4e-22 77.9 6.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.12 EMC84464.1 - 1.2e-17 62.8 4.8 1.2e-17 62.8 3.3 2.2 2 0 0 2 2 2 1 pKID domain bZIP_2 PF07716.10 EMC84464.1 - 4.6e-09 35.9 8.1 8.1e-09 35.1 5.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC84464.1 - 0.00018 21.6 4.9 0.00045 20.4 3.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.6 EMC84464.1 - 0.14 11.4 4.5 0.035 13.4 1.0 1.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 BSMAP PF12280.3 EMC84464.1 - 1.1 9.0 6.2 0.38 10.6 0.3 2.0 2 0 0 2 2 2 0 Brain specific membrane anchored protein AMP-binding PF00501.23 EMC84465.1 - 2.3e-62 210.7 2.1 9.1e-52 175.8 0.1 2.5 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 EMC84465.1 - 2.8e-25 89.0 0.1 5.7e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain La PF05383.12 EMC84466.1 - 3.1e-21 74.9 0.1 5.6e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EMC84466.1 - 0.00023 21.0 0.0 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC84466.1 - 0.051 13.4 0.1 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Claudin_2 PF13903.1 EMC84467.1 - 7.3e-08 32.2 9.3 1e-07 31.8 6.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC84467.1 - 1.7e-05 24.5 12.2 3.2e-05 23.6 8.5 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Ocular_alb PF02101.10 EMC84468.1 - 1.6e-175 583.5 7.6 1.9e-175 583.2 5.3 1.0 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.19 EMC84468.1 - 0.00017 20.7 8.3 0.00017 20.7 5.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) WD40 PF00400.27 EMC84469.1 - 8.8e-70 228.3 27.2 2e-13 49.6 0.2 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC84469.1 - 1.7e-11 44.1 0.7 0.00069 19.3 0.0 3.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EMC84469.1 - 2.8e-10 39.5 0.1 1.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 LisH Nup160 PF11715.3 EMC84469.1 - 0.0013 16.9 2.8 0.063 11.3 0.0 3.3 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EMC84469.1 - 0.0019 17.6 0.0 8.9 5.9 0.0 4.3 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EMC84469.1 - 0.0076 14.1 0.6 0.064 11.0 0.3 2.4 1 1 1 2 2 2 2 IKI3 family K_channel_TID PF07941.6 EMC84469.1 - 0.014 15.6 4.3 0.028 14.6 3.0 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Yae1_N PF09811.4 EMC84470.1 - 1e-31 108.1 113.1 1.5e+04 -73.8 78.4 9.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal fn3 PF00041.16 EMC84472.1 - 6.4e-38 128.7 11.5 1.5e-14 53.9 0.1 4.3 4 0 0 4 4 4 3 Fibronectin type III domain WAP PF00095.16 EMC84472.1 - 5.5e-10 39.0 15.1 5.5e-10 39.0 10.5 2.1 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Interfer-bind PF09294.5 EMC84472.1 - 0.00028 20.9 4.0 0.00089 19.2 0.1 3.2 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III Vif PF00559.12 EMC84472.1 - 0.005 16.7 0.3 0.049 13.5 0.0 2.3 2 0 0 2 2 2 1 Retroviral Vif (Viral infectivity) protein DUF3284 PF11687.3 EMC84472.1 - 0.23 11.1 1.1 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3284) Patatin PF01734.17 EMC84473.1 - 1e-07 32.1 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Sulfatase PF00884.18 EMC84474.1 - 1e-88 297.5 0.0 1.2e-88 297.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMC84474.1 - 3.1e-46 156.8 0.6 5.9e-46 155.9 0.4 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EMC84474.1 - 1.5e-10 40.9 0.0 6.1e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HAD_2 PF13419.1 EMC84475.1 - 2.4e-15 57.1 0.0 3.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC84475.1 - 0.00032 21.1 0.0 0.00041 20.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMC84475.1 - 0.0099 16.0 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMC84475.1 - 0.081 12.8 0.0 0.34 10.8 0.0 1.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase COesterase PF00135.23 EMC84477.1 - 4.5e-189 629.6 0.0 6.2e-189 629.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMC84477.1 - 9.7e-07 28.5 0.1 5.2e-06 26.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sarcoglycan_2 PF05510.8 EMC84477.1 - 0.014 13.7 0.2 0.029 12.6 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon DUF3161 PF11362.3 EMC84478.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Pkinase PF00069.20 EMC84479.1 - 8.4e-66 221.7 0.0 9.6e-66 221.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84479.1 - 3.1e-33 114.9 0.0 3.8e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC84479.1 - 1.7e-07 30.5 0.0 3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC84479.1 - 0.0038 16.9 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC84479.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMC84479.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CagZ PF09053.5 EMC84479.1 - 0.15 11.3 0.1 0.3 10.3 0.1 1.5 1 0 0 1 1 1 0 CagZ I-set PF07679.11 EMC84480.1 - 9.5e-160 518.9 0.0 3.6e-16 58.7 0.0 13.1 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84480.1 - 1.3e-103 339.2 5.8 3.8e-11 42.9 0.0 13.1 13 0 0 13 13 13 12 Immunoglobulin domain Ig_3 PF13927.1 EMC84480.1 - 4.8e-74 244.7 28.4 1.9e-08 34.6 0.1 14.6 13 1 0 13 13 13 12 Immunoglobulin domain ig PF00047.20 EMC84480.1 - 2.5e-60 200.4 12.3 1.1e-06 28.6 0.0 13.8 13 1 0 13 13 13 11 Immunoglobulin domain V-set PF07686.12 EMC84480.1 - 5.1e-59 197.1 8.9 5.1e-06 26.3 0.0 14.5 12 1 1 13 13 13 11 Immunoglobulin V-set domain LRR_8 PF13855.1 EMC84480.1 - 2.5e-28 97.5 12.0 5.8e-11 41.9 1.2 3.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC84480.1 - 2.3e-15 55.8 5.1 0.00069 19.1 0.2 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) Sp38 PF07354.7 EMC84480.1 - 2e-06 26.6 0.1 0.79 8.3 0.0 6.3 7 1 1 8 8 8 2 Zona-pellucida-binding protein (Sp38) LRR_1 PF00560.28 EMC84480.1 - 5.8e-06 25.6 8.5 3.7 7.9 0.0 7.4 7 0 0 7 7 7 1 Leucine Rich Repeat AMP-binding_C_2 PF14535.1 EMC84480.1 - 0.031 14.3 0.5 4.6 7.3 0.0 4.1 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain Sulfatase PF00884.18 EMC84481.1 - 4e-83 279.1 0.0 5.3e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMC84481.1 - 5.3e-50 169.1 0.0 9e-50 168.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EMC84481.1 - 4.3e-11 42.7 0.2 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMC84482.1 - 5.4e-85 285.2 0.0 1.1e-84 284.2 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMC84482.1 - 2.3e-52 176.7 0.1 3.9e-52 175.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EMC84482.1 - 1.3e-10 41.1 0.0 3.1e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMC84482.1 - 0.077 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_transf_8 PF01501.15 EMC84483.1 - 2.2e-42 145.1 0.0 3.4e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EMC84483.1 - 0.0023 17.3 0.1 0.006 15.9 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 EMC84483.1 - 0.0038 17.0 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CD99L2 PF12301.3 EMC84484.1 - 6.7e-21 74.6 0.2 1.4e-19 70.4 0.0 1.7 1 1 1 2 2 2 2 CD99 antigen like protein 2 CD99L2 PF12301.3 EMC84485.1 - 6e-18 65.0 3.2 6.9e-18 64.9 2.2 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 ENOD93 PF03386.9 EMC84485.1 - 0.028 14.1 0.2 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein GtrA PF04138.9 EMC84485.1 - 0.047 13.6 0.8 0.046 13.6 0.6 1.1 1 0 0 1 1 1 0 GtrA-like protein Glycophorin_A PF01102.13 EMC84485.1 - 0.06 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycophorin A DUF4199 PF13858.1 EMC84485.1 - 0.12 12.3 1.2 0.15 11.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Dimer_Tnp_hAT PF05699.9 EMC84486.1 - 2e-14 52.9 0.1 6.1e-14 51.4 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 EMC84486.1 - 4.5e-12 45.5 1.0 1e-11 44.4 0.7 1.6 1 0 0 1 1 1 1 BED zinc finger DUF4413 PF14372.1 EMC84486.1 - 0.00076 19.4 4.4 0.0012 18.7 0.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4413) adh_short PF00106.20 EMC84487.1 - 6e-08 32.7 0.2 1e-06 28.7 0.0 2.5 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EMC84487.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC84487.1 - 0.022 14.1 0.2 0.31 10.4 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMC84487.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_2 PF00891.13 EMC84488.1 - 3.5e-72 242.4 0.0 4.3e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMC84488.1 - 1.6e-08 35.1 0.0 2.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC84488.1 - 2.1e-07 30.7 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC84488.1 - 5.7e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84488.1 - 6e-05 23.4 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC84488.1 - 0.00013 21.6 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC84488.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EMC84488.1 - 0.027 13.5 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Peptidase_M57 PF12388.3 EMC84488.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase RRM_1 PF00076.17 EMC84489.1 - 0.00092 18.7 0.5 0.71 9.5 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.16 EMC84490.1 - 1.5e-45 155.3 26.8 2e-45 154.9 18.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC84490.1 - 0.029 13.5 25.6 0.04 13.0 17.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv VHS PF00790.14 EMC84490.1 - 0.04 13.5 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 VHS domain Endomucin PF07010.7 EMC84490.1 - 0.059 12.6 0.4 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 Endomucin DUF4131 PF13567.1 EMC84490.1 - 7 6.0 13.9 0.16 11.3 2.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_2 PF00891.13 EMC84491.1 - 1.1e-58 198.2 0.0 1.9e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Maf PF02545.9 EMC84491.1 - 6.4e-46 155.9 0.0 1e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Maf-like protein Methyltransf_23 PF13489.1 EMC84491.1 - 7.4e-06 25.7 0.0 2.1e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC84491.1 - 0.00015 22.0 0.0 0.0019 18.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC84491.1 - 0.00038 21.0 0.0 0.0017 18.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC84491.1 - 0.002 18.5 0.0 0.011 16.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Mito_carr PF00153.22 EMC84492.1 - 7.5e-58 192.2 1.6 2.5e-22 78.3 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein IL6Ra-bind PF09240.5 EMC84493.1 - 1.1e-22 80.0 0.2 1.1e-22 80.0 0.2 2.2 3 1 0 3 3 3 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 EMC84493.1 - 0.00021 21.2 2.3 0.00025 21.0 0.3 2.0 2 1 0 2 2 2 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 EMC84495.1 - 1.5e-18 66.7 0.9 2.5e-18 66.0 0.1 1.8 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 EMC84495.1 - 0.015 15.3 0.5 0.015 15.3 0.4 1.9 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 EMC84496.1 - 9.4e-19 67.4 0.4 2.1e-18 66.3 0.3 1.6 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding fn3 PF00041.16 EMC84496.1 - 0.0052 16.8 0.1 0.071 13.2 0.0 2.4 2 1 0 2 2 2 1 Fibronectin type III domain Tissue_fac PF01108.12 EMC84496.1 - 0.19 11.5 3.2 1.3 8.7 0.1 2.5 2 1 0 2 2 2 0 Tissue factor IL6Ra-bind PF09240.5 EMC84497.1 - 1.7e-12 47.3 0.7 2.6e-12 46.7 0.5 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 EMC84497.1 - 0.064 12.9 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Tissue factor SKG6 PF08693.5 EMC84498.1 - 0.02 14.1 0.1 0.043 13.1 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tissue_fac PF01108.12 EMC84498.1 - 0.27 10.9 3.7 1.8 8.3 0.3 2.8 3 0 0 3 3 3 0 Tissue factor Homeobox PF00046.24 EMC84500.1 - 3.1e-25 87.5 2.7 5.1e-25 86.8 1.8 1.4 1 0 0 1 1 1 1 Homeobox domain MRP-L20 PF12824.2 EMC84500.1 - 0.0042 17.0 0.5 0.0077 16.2 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.6 EMC84500.1 - 0.0063 16.1 0.1 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain EF-hand_7 PF13499.1 EMC84501.1 - 2.8e-19 69.0 3.5 7.9e-16 57.9 2.6 3.7 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC84501.1 - 2.8e-10 38.7 0.1 0.033 13.4 0.0 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EMC84501.1 - 3.4e-08 32.7 0.5 0.12 12.3 0.0 6.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 EMC84501.1 - 8.4e-08 31.7 0.2 0.55 9.8 0.0 6.2 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC84501.1 - 1.3e-06 27.4 0.1 0.00061 19.0 0.0 4.1 5 0 0 5 5 5 1 EF hand SPARC_Ca_bdg PF10591.4 EMC84501.1 - 0.028 14.4 3.8 2.6 8.0 0.2 2.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4187 PF13821.1 EMC84501.1 - 0.06 12.9 0.8 0.16 11.6 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) STAG PF08514.6 EMC84503.1 - 1.2e-38 131.4 6.2 1.7e-38 130.9 0.3 2.6 2 0 0 2 2 2 2 STAG domain MMR_HSR1 PF01926.18 EMC84504.1 - 1.1e-14 54.3 0.1 4.5e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 EMC84504.1 - 7e-06 26.0 0.1 2.2e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal FeoB_N PF02421.13 EMC84504.1 - 0.00027 20.2 1.0 0.0016 17.7 0.7 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMC84504.1 - 0.00057 19.3 0.1 0.65 9.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMC84504.1 - 0.00074 19.0 0.2 0.023 14.1 0.0 2.7 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EMC84504.1 - 0.011 16.1 0.0 0.031 14.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 EMC84504.1 - 0.027 14.1 0.1 0.072 12.8 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EMC84504.1 - 0.028 14.7 0.6 0.06 13.6 0.1 2.0 1 1 1 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EMC84504.1 - 0.028 14.2 0.2 0.17 11.6 0.0 2.3 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EMC84504.1 - 0.033 13.9 0.5 0.092 12.4 0.0 2.0 2 1 0 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 EMC84504.1 - 0.035 12.7 0.3 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EMC84504.1 - 0.044 13.6 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMC84504.1 - 0.11 11.6 0.0 4.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 SGL PF08450.7 EMC84505.1 - 1e-80 270.6 0.0 1.2e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Integrase_AP2 PF14657.1 EMC84505.1 - 0.15 11.8 0.3 0.42 10.4 0.1 1.8 2 0 0 2 2 2 0 AP2-like DNA-binding integrase domain Ldh_2 PF02615.9 EMC84505.1 - 0.17 10.5 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase SGL PF08450.7 EMC84506.1 - 9e-80 267.5 0.1 1e-79 267.4 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 EMC84506.1 - 0.017 14.5 0.0 0.85 9.0 0.0 2.2 1 1 0 2 2 2 0 PQQ-like domain Reg_prop PF07494.6 EMC84506.1 - 0.018 15.0 0.0 0.29 11.2 0.0 3.0 2 1 0 2 2 2 0 Two component regulator propeller NHL PF01436.16 EMC84506.1 - 0.039 13.9 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 NHL repeat zf-HC5HC2H_2 PF13832.1 EMC84507.1 - 1.1e-30 105.8 7.9 1.1e-30 105.8 5.5 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC84507.1 - 3.7e-25 87.8 6.0 3.7e-25 87.8 4.2 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EMC84507.1 - 1.6e-24 86.9 1.0 1.6e-24 86.9 0.7 2.8 3 0 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 EMC84507.1 - 2.1e-12 46.1 6.8 2.1e-12 46.1 4.7 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 EMC84507.1 - 1.5e-09 37.3 9.5 1.5e-09 37.3 6.6 3.5 2 1 1 3 3 3 2 PHD-finger C1_1 PF00130.17 EMC84507.1 - 0.0022 17.7 3.0 0.0022 17.7 2.1 3.7 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMC84507.1 - 0.72 9.6 19.1 0.086 12.5 4.4 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TBCC PF07986.7 EMC84508.1 - 4.9e-45 151.8 5.3 7.4e-45 151.2 3.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C NDK PF00334.14 EMC84508.1 - 3.6e-05 23.5 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CAP_C PF08603.6 EMC84508.1 - 0.00056 19.2 1.2 0.00097 18.5 0.8 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TMEM51 PF15345.1 EMC84509.1 - 0.0098 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 PBP1_TM PF14812.1 EMC84509.1 - 6.5 7.1 8.0 13 6.1 5.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM51 PF15345.1 EMC84510.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 PBP1_TM PF14812.1 EMC84510.1 - 1.2 9.4 5.9 2.5 8.4 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spc97_Spc98 PF04130.8 EMC84511.1 - 2.5e-113 379.2 14.8 3.1e-113 378.9 10.2 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GD_AH_C PF04295.8 EMC84511.1 - 0.26 9.8 0.0 0.41 9.2 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus fn3 PF00041.16 EMC84512.1 - 0.00015 21.7 0.7 0.00021 21.3 0.0 1.6 2 0 0 2 2 2 1 Fibronectin type III domain FAM163 PF15069.1 EMC84512.1 - 0.0031 18.1 0.6 0.0082 16.7 0.0 1.9 1 1 1 2 2 2 1 FAM163 family DUF347 PF03988.7 EMC84512.1 - 0.099 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Mg_trans_NIPA PF05653.9 EMC84513.1 - 1.4e-146 487.1 13.3 1.6e-146 486.9 9.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMC84513.1 - 3.9e-09 36.7 1.8 3.9e-09 36.7 1.2 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC84513.1 - 4.7e-08 33.1 5.7 4.7e-08 33.1 3.9 3.8 3 1 2 5 5 5 1 EamA-like transporter family Mg_trans_NIPA PF05653.9 EMC84514.1 - 2.8e-76 256.3 15.2 3.2e-76 256.1 10.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMC84514.1 - 0.0031 17.6 2.4 0.0031 17.6 1.6 3.6 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC84514.1 - 0.0086 16.1 6.7 0.0086 16.1 4.6 3.2 2 1 0 3 3 3 2 EamA-like transporter family MgtE PF01769.11 EMC84514.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.6 1 1 1 2 2 2 0 Divalent cation transporter TPT PF03151.11 EMC84514.1 - 0.22 11.1 18.6 0.8 9.3 6.1 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family Cortexin PF11057.3 EMC84514.1 - 0.41 10.2 2.8 0.33 10.5 0.2 2.0 2 0 0 2 2 2 0 Cortexin of kidney DUF2678 PF10856.3 EMC84514.1 - 0.78 9.4 16.9 1.4 8.6 1.6 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF2678) RCC1 PF00415.13 EMC84515.1 - 3.9e-235 760.1 89.6 8.8e-16 57.8 0.1 21.8 21 0 0 21 21 21 19 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC84515.1 - 4.7e-92 300.0 128.4 4.1e-08 32.6 0.1 22.2 23 0 0 23 23 22 17 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 EMC84515.1 - 9.7e-63 212.2 0.0 1.7e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cul7 PF11515.3 EMC84515.1 - 6.6e-40 134.8 0.7 6.6e-40 134.8 0.5 1.9 2 0 0 2 2 1 1 Mouse development and cellular proliferation protein Cullin-7 MIB_HERC2 PF06701.8 EMC84515.1 - 2e-26 91.7 3.0 2e-26 91.7 2.1 5.2 6 0 0 6 6 4 1 Mib_herc2 Cyt-b5 PF00173.23 EMC84515.1 - 3.4e-12 45.9 0.0 7.4e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.12 EMC84515.1 - 3e-09 36.2 7.0 7.1e-09 35.0 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type APC10 PF03256.11 EMC84515.1 - 3.5e-05 23.4 0.0 6.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SUKH-3 PF14433.1 EMC84515.1 - 0.0014 18.4 12.4 6.4 6.5 0.0 7.2 9 0 0 9 9 9 2 SUKH-3 immunity protein Ubie_methyltran PF01209.13 EMC84515.1 - 0.085 11.9 0.7 17 4.4 0.0 3.7 4 0 0 4 4 4 0 ubiE/COQ5 methyltransferase family CBM_X PF06204.6 EMC84515.1 - 0.75 9.3 17.2 12 5.4 0.0 8.2 11 0 0 11 11 11 0 Putative carbohydrate binding domain CitMHS PF03600.11 EMC84516.1 - 2.1e-76 256.8 18.6 4.2e-71 239.3 5.1 2.3 2 1 1 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.14 EMC84516.1 - 3.4e-16 59.1 30.4 3.6e-11 42.6 8.0 2.6 2 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region ArsB PF02040.10 EMC84516.1 - 1e-12 47.7 25.4 5.9e-08 32.1 8.1 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein MatC_N PF07158.6 EMC84516.1 - 1.4 8.7 23.9 0.011 15.4 8.2 2.6 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Neur_chan_memb PF02932.11 EMC84517.1 - 7.4e-46 156.9 10.0 9.2e-41 140.2 4.7 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RDD PF06271.7 EMC84517.1 - 3.4 7.5 11.4 0.26 11.1 4.3 1.8 2 1 0 2 2 2 0 RDD family Neur_chan_LBD PF02931.18 EMC84518.1 - 4.9e-51 172.9 0.0 6.8e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC84518.1 - 1e-46 159.8 5.8 8.2e-39 133.9 2.2 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 EMC84519.1 - 2.5e-55 187.9 0.9 1.1e-54 185.8 0.6 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC84519.1 - 4.9e-47 159.8 0.0 7.3e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain OAD_gamma PF04277.8 EMC84519.1 - 0.087 13.2 0.1 0.85 10.0 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain HECT PF00632.20 EMC84520.1 - 2.7e-85 286.3 0.3 1e-84 284.4 0.1 2.1 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AhpC-TSA_2 PF13911.1 EMC84520.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme cNMP_binding PF00027.24 EMC84521.1 - 2.2e-17 62.6 0.0 3.8e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 EMC84521.1 - 1.4e-16 60.3 3.3 2e-16 59.8 2.3 1.3 1 0 0 1 1 1 1 Ion transport protein Ycf1 PF05758.7 EMC84521.1 - 6.2e-05 20.9 1.1 0.00014 19.8 0.8 1.5 1 0 0 1 1 1 1 Ycf1 CDC45 PF02724.9 EMC84521.1 - 0.00032 18.8 1.0 0.00032 18.8 0.7 1.9 2 0 0 2 2 2 1 CDC45-like protein RR_TM4-6 PF06459.7 EMC84521.1 - 0.0011 18.9 8.4 0.0011 18.9 5.8 1.9 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.5 EMC84521.1 - 0.0017 18.1 13.9 0.0017 18.1 9.7 3.0 3 0 0 3 3 3 1 Peptidase family S49 N-terminal GAGA_bind PF06217.7 EMC84521.1 - 0.0085 16.0 6.4 0.0085 16.0 4.4 1.7 2 0 0 2 2 2 1 GAGA binding protein-like family AAA_23 PF13476.1 EMC84521.1 - 0.05 13.9 19.6 0.033 14.5 4.4 2.5 2 1 0 2 2 2 0 AAA domain DDHD PF02862.12 EMC84521.1 - 0.15 11.8 7.1 0.35 10.6 4.9 1.6 1 0 0 1 1 1 0 DDHD domain DUF948 PF06103.6 EMC84521.1 - 0.16 11.8 0.6 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ion_trans_2 PF07885.11 EMC84521.1 - 0.17 11.6 5.7 0.59 9.8 4.0 2.0 1 1 0 1 1 1 0 Ion channel NARP1 PF12569.3 EMC84521.1 - 0.18 10.5 26.2 0.0078 15.0 11.1 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Zip PF02535.17 EMC84521.1 - 0.19 10.6 2.3 0.29 10.1 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.3 EMC84521.1 - 0.56 8.7 13.2 1 7.9 9.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 zf-DHHC PF01529.15 EMC84521.1 - 1.1 8.6 6.8 8.2 5.7 0.7 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF1510 PF07423.6 EMC84521.1 - 1.3 8.3 26.1 3.2 7.0 18.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VWA_3 PF13768.1 EMC84522.1 - 0.0042 16.8 0.2 0.0062 16.2 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3651 PF12371.3 EMC84523.1 - 1.4e-46 156.3 14.9 2.6e-24 85.0 0.8 5.2 5 0 0 5 5 5 3 Protein of unknown function (DUF3651) Transglut_C PF00927.17 EMC84523.1 - 0.049 13.6 2.2 16 5.5 0.0 4.4 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain C2 PF00168.25 EMC84524.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain NHR2 PF08788.6 EMC84524.1 - 0.006 16.0 0.7 0.18 11.3 0.1 2.7 2 0 0 2 2 2 1 NHR2 domain like Pet191_N PF10203.4 EMC84525.1 - 2.4e-21 75.5 4.4 2.8e-21 75.3 3.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EMC84525.1 - 0.045 13.6 3.2 2.9 7.9 0.4 2.4 2 1 0 2 2 2 0 CHCH domain UNC-50 PF05216.8 EMC84526.1 - 2.5e-90 301.7 21.8 2.9e-90 301.5 15.1 1.0 1 0 0 1 1 1 1 UNC-50 family Glyco_transf_54 PF04666.8 EMC84527.1 - 2.5e-133 443.4 0.9 3.4e-133 443.0 0.7 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3989 PF13150.1 EMC84527.1 - 0.022 14.1 0.2 0.52 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) GAS PF13851.1 EMC84527.1 - 0.054 12.6 1.6 0.099 11.8 1.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4592 PF15262.1 EMC84528.1 - 1.7e-30 106.2 4.8 1.7e-30 106.2 3.3 3.0 2 2 0 2 2 2 1 Domain of unknown function (DUF4592) SH2 PF00017.19 EMC84530.1 - 8.6e-16 57.5 0.1 1.5e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 SH2 domain SIT PF15330.1 EMC84531.1 - 5.2e-32 110.1 1.1 5.2e-32 110.1 0.7 1.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT DUF2663 PF10864.3 EMC84531.1 - 0.024 14.8 0.0 0.42 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) EF-hand_1 PF00036.27 EMC84532.1 - 8.5e-23 77.8 10.5 1.4e-06 27.1 0.7 4.7 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EMC84532.1 - 2.6e-21 73.5 9.4 5.9e-06 25.7 0.6 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EMC84532.1 - 1.1e-19 70.3 10.2 2e-12 47.0 0.2 3.2 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC84532.1 - 5.8e-17 60.1 12.5 2.3e-05 23.5 1.4 4.8 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 EMC84532.1 - 1.2e-15 56.8 2.9 2.7e-08 33.2 0.2 2.8 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC84532.1 - 3.2e-07 30.3 0.2 2.4e-05 24.3 0.0 2.5 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC84532.1 - 0.00013 21.6 6.6 0.059 13.1 0.4 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMC84532.1 - 0.0036 16.9 0.3 0.6 9.8 0.0 2.9 3 0 0 3 3 3 1 EF hand VCBS PF13517.1 EMC84532.1 - 0.43 10.9 2.8 1.2 9.5 1.4 2.2 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella B PF02216.11 EMC84534.1 - 0.012 15.4 0.0 0.089 12.5 0.0 2.1 1 1 0 1 1 1 0 B domain C2-set_2 PF08205.7 EMC84535.1 - 1.9e-12 46.8 0.1 5.6e-12 45.4 0.0 1.8 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 EMC84535.1 - 4.3e-10 39.5 0.1 5.8e-06 26.3 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC84535.1 - 2e-08 34.6 0.4 4.1e-05 24.0 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC84535.1 - 5.4e-05 23.2 0.7 0.0041 17.1 0.0 2.8 2 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.11 EMC84535.1 - 0.00021 21.0 0.1 0.046 13.5 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain C1-set PF07654.10 EMC84535.1 - 0.11 12.4 0.1 4.3 7.4 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin C1-set domain V-set PF07686.12 EMC84536.1 - 2.1e-06 27.6 0.0 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 EMC84536.1 - 0.043 13.9 0.7 4 7.6 0.0 2.9 2 1 0 2 2 2 0 Immunoglobulin domain PI-PLC-X PF00388.14 EMC84537.1 - 1.4e-05 24.5 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Abhydrolase_6 PF12697.2 EMC84538.1 - 1.5e-17 64.2 0.0 3.4e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC84538.1 - 1.7e-15 57.0 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC84538.1 - 5.4e-13 49.0 0.1 3.9e-12 46.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC84538.1 - 3.1e-10 39.6 0.0 4.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMC84538.1 - 0.011 15.1 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EMC84538.1 - 0.02 14.3 0.1 0.054 12.9 0.1 1.8 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 EMC84538.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 EMC84538.1 - 0.032 13.9 0.0 0.13 11.9 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) DUF2920 PF11144.3 EMC84538.1 - 0.046 12.7 0.0 0.083 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2920) B5 PF03484.10 EMC84538.1 - 0.079 12.8 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase B5 domain Ser_hydrolase PF06821.8 EMC84538.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Vint PF14623.1 EMC84538.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Hint-domain CH PF00307.26 EMC84539.1 - 1.4e-13 50.7 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 EMC84539.1 - 1.7e-13 49.6 3.6 1.7e-13 49.6 2.5 2.4 3 0 0 3 3 3 1 Calponin family repeat Trypsin PF00089.21 EMC84540.1 - 5.8e-65 218.9 0.4 1.2e-64 217.9 0.3 1.6 1 0 0 1 1 1 1 Trypsin SEA PF01390.15 EMC84540.1 - 4.9e-26 90.5 0.7 8.5e-26 89.7 0.5 1.4 1 0 0 1 1 1 1 SEA domain Ldl_recept_a PF00057.13 EMC84540.1 - 7.4e-24 83.3 38.7 1.9e-09 37.2 5.2 3.7 2 1 1 3 3 3 3 Low-density lipoprotein receptor domain class A CUB PF00431.15 EMC84540.1 - 5.8e-14 52.0 0.6 9.1e-06 25.7 0.2 2.9 2 0 0 2 2 2 2 CUB domain Peptidase_S6 PF02395.11 EMC84540.1 - 0.13 10.4 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin A1 protease Trypsin PF00089.21 EMC84541.1 - 5.3e-74 248.4 0.1 6e-74 248.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC84541.1 - 7.7e-06 25.3 0.1 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 EMC84541.1 - 0.00034 20.0 0.0 0.019 14.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF316) Ig_2 PF13895.1 EMC84542.1 - 1.5e-10 41.0 1.1 1.7e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC84542.1 - 2.3e-10 40.1 1.0 4.5e-05 23.2 0.3 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain C2-set_2 PF08205.7 EMC84542.1 - 5.3e-10 39.0 0.8 1.4e-07 31.2 0.1 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC84542.1 - 1.8e-08 34.2 0.6 4.2e-08 33.0 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 EMC84542.1 - 2.4e-08 33.9 4.2 2e-06 27.8 0.2 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC84542.1 - 1.7e-06 28.4 3.9 0.0092 16.4 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC84543.1 - 8e-08 32.1 0.0 9.3e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC84543.1 - 9.3e-06 25.6 0.2 2.6e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC84543.1 - 7.1e-05 22.5 0.0 8.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84543.1 - 0.0011 19.0 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC84544.1 - 5.4e-14 51.8 0.2 3.3e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 EMC84544.1 - 7.2e-14 51.6 0.4 1.5e-13 50.6 0.3 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC84544.1 - 1.5e-06 28.2 4.6 3.3e-06 27.1 0.4 2.4 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 EMC84544.1 - 1.1e-05 25.4 2.3 1.1e-05 25.4 1.6 3.1 2 2 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC84544.1 - 0.00017 21.3 1.7 0.027 14.3 0.1 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 EMC84544.1 - 0.00042 20.7 7.8 0.081 13.4 1.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain AKAP95 PF04988.7 EMC84547.1 - 0.00056 19.7 1.8 0.00086 19.1 1.0 1.5 1 1 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 EMC84547.1 - 0.0036 17.3 2.2 0.0041 17.2 0.8 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Mut7-C PF01927.11 EMC84547.1 - 0.022 14.7 1.8 0.66 9.9 0.1 2.3 1 1 1 2 2 2 0 Mut7-C RNAse domain Peptidase_S76 PF13611.1 EMC84547.1 - 0.17 11.9 1.3 0.86 9.7 0.2 2.0 1 1 1 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 zf-met PF12874.2 EMC84547.1 - 1.6 9.0 6.0 33 4.8 4.2 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EMC84549.1 - 1.6e-06 28.0 43.7 0.028 14.7 1.4 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-met PF12874.2 EMC84549.1 - 0.0062 16.7 11.3 0.2 11.8 0.4 4.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.10 EMC84549.1 - 0.2 11.4 26.8 0.15 11.8 3.2 3.8 3 0 0 3 3 3 0 BED zinc finger Yippee-Mis18 PF03226.9 EMC84549.1 - 0.38 10.8 11.7 0.4 10.7 1.4 3.3 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_4 PF13894.1 EMC84549.1 - 0.46 10.9 39.3 0.19 12.1 0.5 6.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC84549.1 - 2.4 8.1 20.9 1.3 9.0 2.6 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger DUF4518 PF15008.1 EMC84550.1 - 2.4e-95 318.5 0.1 2.7e-95 318.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Pkinase_Tyr PF07714.12 EMC84551.1 - 2.2e-96 321.8 0.0 3.2e-96 321.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC84551.1 - 1.6e-71 239.8 0.2 3.6e-71 238.6 0.2 1.7 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC84551.1 - 3.2e-47 160.8 0.0 5.1e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC84551.1 - 2e-35 120.7 0.7 1.1e-16 60.7 0.4 3.0 2 0 0 2 2 2 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC84551.1 - 1e-25 89.9 0.0 2.5e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 EMC84551.1 - 1.7e-13 50.5 0.0 3.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC84551.1 - 5e-11 42.2 0.0 1.5e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC84551.1 - 1.1e-07 31.3 4.1 1.1e-07 31.3 2.8 3.1 2 1 1 3 3 3 1 GCC2 and GCC3 Interfer-bind PF09294.5 EMC84551.1 - 0.0023 17.9 0.0 0.16 12.0 0.0 3.2 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III TMEM154 PF15102.1 EMC84551.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Kdo PF06293.9 EMC84551.1 - 0.03 13.3 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1934 PF09148.5 EMC84551.1 - 0.049 13.3 0.3 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1934) Rax2 PF12768.2 EMC84551.1 - 0.056 12.6 1.0 0.19 10.9 0.3 1.9 1 1 0 2 2 2 0 Cortical protein marker for cell polarity Laminin_G_1 PF00054.18 EMC84552.1 - 2.8e-32 111.5 0.2 1.9e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.19 EMC84552.1 - 4.9e-25 88.0 0.0 1.1e-14 54.6 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.10 EMC84552.1 - 2.6e-19 68.9 59.6 3.9e-08 33.1 6.3 5.0 4 1 0 4 4 4 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 EMC84552.1 - 4.4e-17 61.9 58.1 6.2e-08 32.6 7.6 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site Gla PF00594.15 EMC84552.1 - 1.6e-15 56.4 8.2 3.7e-15 55.3 5.7 1.7 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain EGF PF00008.22 EMC84552.1 - 2.1e-12 46.7 49.5 4.6e-05 23.2 4.4 4.6 4 0 0 4 4 4 4 EGF-like domain cEGF PF12662.2 EMC84552.1 - 4.3e-10 39.0 39.3 2.1e-06 27.2 1.9 5.8 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.2 EMC84552.1 - 1.5e-07 31.2 39.2 0.0041 17.0 4.4 4.7 4 0 0 4 4 4 3 EGF domain hEGF PF12661.2 EMC84552.1 - 0.0049 16.8 12.9 0.017 15.1 2.3 3.8 3 0 0 3 3 3 1 Human growth factor-like EGF Arf PF00025.16 EMC84553.1 - 3.2e-42 143.7 0.2 7e-42 142.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EMC84553.1 - 3e-07 29.9 0.0 7.5e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC84553.1 - 4e-06 26.1 0.0 4e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC84553.1 - 3.2e-05 22.8 0.0 3.2e-05 22.8 0.0 3.6 2 2 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EMC84553.1 - 6e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC84553.1 - 0.0016 18.9 0.4 0.011 16.2 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DUF1395 PF07160.7 EMC84553.1 - 0.45 9.9 9.8 1.2 8.6 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) SNARE PF05739.14 EMC84554.1 - 1.1e-13 50.6 4.3 1.1e-13 50.6 3.0 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EMC84554.1 - 1.8e-08 34.4 5.6 1.8e-08 34.4 3.9 3.1 3 0 0 3 3 3 1 Syntaxin Syntaxin-6_N PF09177.6 EMC84554.1 - 0.035 14.4 1.5 0.035 14.4 1.0 3.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Fe_bilin_red PF05996.7 EMC84554.1 - 0.08 12.4 6.0 0.022 14.2 1.5 1.9 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase ALO PF04030.9 EMC84554.1 - 0.21 11.1 2.9 0.18 11.3 0.9 1.7 1 1 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Hepcidin PF06446.7 EMC84554.1 - 0.32 11.4 12.2 0.059 13.7 4.9 2.5 3 0 0 3 3 3 0 Hepcidin Filo_VP35 PF02097.10 EMC84554.1 - 0.39 9.8 10.2 0.051 12.7 1.4 2.1 2 0 0 2 2 2 0 Filoviridae VP35 DUF812 PF05667.6 EMC84554.1 - 1.5 7.1 24.9 1.5 7.2 6.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CDO_I PF05995.7 EMC84554.1 - 2.4 7.3 5.6 3 6.9 0.3 2.7 2 1 1 3 3 3 0 Cysteine dioxygenase type I DUF948 PF06103.6 EMC84554.1 - 4.8 7.1 11.9 4 7.3 0.3 3.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TEX12 PF15219.1 EMC84554.1 - 5.1 7.1 7.7 1.7 8.6 0.6 2.4 2 0 0 2 2 2 0 Testis-expressed 12 Fib_alpha PF08702.5 EMC84554.1 - 5.5 7.1 25.2 0.93 9.6 4.4 3.6 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Nol1_Nop2_Fmu PF01189.12 EMC84555.1 - 1.2e-23 83.9 0.0 1.6e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EMC84555.1 - 1.7e-07 31.3 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC84555.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EMC84555.1 - 0.00059 20.4 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pkinase_Tyr PF07714.12 EMC84556.1 - 6.6e-90 300.6 0.0 3.1e-71 239.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EMC84556.1 - 4.1e-41 140.8 0.0 9e-41 139.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC84556.1 - 3e-27 94.5 0.0 2e-13 50.2 0.0 2.8 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC84556.1 - 2.7e-23 82.1 0.0 5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 EMC84556.1 - 1.5e-20 73.0 0.0 3.2e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC84556.1 - 4.2e-16 58.5 0.0 8.9e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC84556.1 - 0.00029 20.3 2.1 0.00029 20.3 1.4 3.0 2 1 1 3 3 3 1 GCC2 and GCC3 SusE PF14292.1 EMC84556.1 - 0.0013 18.5 0.1 1.6 8.5 0.0 2.7 2 1 1 3 3 3 2 SusE outer membrane protein Tissue_fac PF01108.12 EMC84556.1 - 0.028 14.1 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Tissue factor Kdo PF06293.9 EMC84556.1 - 0.088 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.1 EMC84556.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family UPF0542 PF15086.1 EMC84556.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Arf PF00025.16 EMC84557.1 - 9.1e-55 184.5 0.0 1.1e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC84557.1 - 1.8e-12 46.6 2.4 7.2e-08 31.5 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMC84557.1 - 7.2e-11 41.7 0.0 8.3e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC84557.1 - 1.1e-10 41.0 0.1 1.4e-10 40.6 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC84557.1 - 5.6e-09 35.9 0.0 7.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC84557.1 - 1.6e-07 30.7 0.1 1.8e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC84557.1 - 3.7e-05 24.2 0.0 5.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC84557.1 - 0.0017 17.7 0.0 0.012 15.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMC84557.1 - 0.0047 17.0 0.1 0.04 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC84557.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.6 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EMC84557.1 - 0.013 14.8 0.1 0.031 13.5 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 EMC84557.1 - 0.041 13.3 0.1 0.85 9.0 0.0 2.1 1 1 1 2 2 2 0 FtsK/SpoIIIE family Crystall PF00030.14 EMC84559.1 - 3.1e-97 318.6 4.1 7.6e-22 77.0 0.2 6.7 6 0 0 6 6 6 6 Beta/Gamma crystallin Ricin_B_lectin PF00652.17 EMC84559.1 - 3.4e-18 65.8 0.2 7.7e-18 64.7 0.2 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EMC84559.1 - 2.4e-12 47.1 0.5 8.4e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Crystall_3 PF08964.5 EMC84559.1 - 0.013 15.1 2.0 4 7.2 0.0 5.0 5 0 0 5 5 5 0 Beta/Gamma crystallin Cupin_4 PF08007.7 EMC84560.1 - 8.8e-91 304.4 0.0 1.2e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 EMC84560.1 - 1e-06 28.4 0.1 8e-05 22.2 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EMC84560.1 - 0.0003 20.2 0.1 0.0086 15.5 0.1 2.3 1 1 0 1 1 1 1 Cupin domain T2SF PF00482.18 EMC84560.1 - 0.028 14.3 0.1 0.069 13.0 0.0 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F AraC_binding PF02311.14 EMC84560.1 - 0.098 12.3 0.6 0.44 10.2 0.1 2.4 2 1 0 2 2 2 0 AraC-like ligand binding domain Neur_chan_LBD PF02931.18 EMC84561.1 - 8.9e-54 181.9 0.0 1.4e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC84561.1 - 5.4e-39 134.4 9.5 8.8e-34 117.4 2.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 EMC84562.1 - 5.4e-27 92.6 12.9 3.7e-05 23.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat MPC PF03650.8 EMC84563.1 - 7.7e-33 112.9 1.0 8.3e-33 112.8 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) V-set PF07686.12 EMC84564.1 - 6e-19 68.0 0.0 1e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC84564.1 - 6.1e-05 22.8 0.1 0.00025 20.8 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84564.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Myelin-PO_C PF10570.4 EMC84564.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Myelin-PO cytoplasmic C-term p65 binding region ig PF00047.20 EMC84564.1 - 0.0037 17.3 0.6 0.046 13.8 0.4 2.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84564.1 - 0.0068 16.8 1.6 0.095 13.2 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.11 EMC84564.1 - 0.013 13.7 0.0 0.71 8.0 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E CAP-ZIP_m PF15255.1 EMC84565.1 - 6.1e-23 81.2 0.9 2.3e-22 79.4 0.6 2.0 1 0 0 1 1 1 1 WASH complex subunit CAP-Z interacting, central region Pyrid_oxidase_2 PF13883.1 EMC84566.1 - 8.7e-59 198.0 0.0 9.8e-59 197.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EMC84566.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ITAM PF02189.10 EMC84567.1 - 1.7e-12 46.6 0.8 5.2e-06 26.3 0.2 2.3 2 0 0 2 2 2 2 Immunoreceptor tyrosine-based activation motif Pou PF00157.12 EMC84568.1 - 2.1e-39 132.9 0.1 5.2e-39 131.7 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 EMC84568.1 - 1.3e-17 63.0 2.7 3.4e-17 61.7 1.9 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC84568.1 - 0.12 12.0 0.1 0.32 10.7 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Popeye PF04831.8 EMC84569.1 - 6.4e-75 250.0 0.3 1.2e-74 249.0 0.1 1.5 2 0 0 2 2 2 1 Popeye protein conserved region cNMP_binding PF00027.24 EMC84569.1 - 0.00015 21.4 0.1 0.00047 19.9 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain CAP_N PF01213.14 EMC84569.1 - 2.9 7.1 4.6 4.2 6.5 3.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EMC84569.1 - 9.6 5.4 6.9 14 4.9 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PaaSYMP PF14738.1 EMC84570.1 - 3.6e-60 202.1 7.5 6.8e-60 201.2 5.2 1.5 1 0 0 1 1 1 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DUF572 PF04502.8 EMC84570.1 - 0.0032 16.7 3.8 0.0046 16.2 2.6 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) Pkinase PF00069.20 EMC84571.1 - 2.5e-64 216.9 0.0 3e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84571.1 - 2.8e-24 85.5 0.0 3.8e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC84571.1 - 6.9e-06 25.2 0.0 4.1e-05 22.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EMC84571.1 - 0.0051 16.5 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC84571.1 - 0.052 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase 7tm_3 PF00003.17 EMC84572.1 - 6.8e-20 71.4 17.4 9.4e-20 70.9 12.1 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Sec2p PF06428.6 EMC84572.1 - 0.11 12.2 0.2 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Kazal_2 PF07648.10 EMC84573.1 - 3.8e-13 49.1 4.3 3.8e-13 49.1 3.0 2.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC84573.1 - 9.3e-09 35.1 10.5 9.3e-09 35.1 7.3 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 EMC84573.1 - 2.9e-06 26.9 2.0 2.9e-06 26.9 1.4 2.6 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_7 PF13499.1 EMC84573.1 - 0.00035 20.6 4.5 0.00089 19.3 0.4 2.8 3 1 0 3 3 3 1 EF-hand domain pair Pacifastin_I PF05375.8 EMC84573.1 - 0.00054 19.4 9.3 0.00054 19.4 6.4 2.8 3 1 0 3 3 3 1 Pacifastin inhibitor (LCMII) EF-hand_1 PF00036.27 EMC84573.1 - 0.00086 18.4 0.9 0.06 12.6 0.0 2.8 3 0 0 3 3 3 1 EF hand Hormone_3 PF00159.13 EMC84573.1 - 0.18 11.8 0.4 0.36 10.8 0.3 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide EF-hand_6 PF13405.1 EMC84573.1 - 0.18 11.7 0.4 7.8 6.6 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 EMC84573.1 - 0.28 10.8 1.1 0.87 9.2 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_like PF09279.6 EMC84573.1 - 1.2 9.2 4.5 11 6.0 0.6 2.6 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like NDUF_B4 PF07225.7 EMC84574.1 - 3.2e-27 94.8 0.1 3.4e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HgmA PF04209.8 EMC84575.1 - 8.9e-205 679.9 0.0 1e-204 679.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ras PF00071.17 EMC84576.1 - 1.1e-08 34.6 0.0 3.9e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC84576.1 - 4.1e-07 30.5 0.0 2.4e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 EMC84576.1 - 0.13 11.4 0.1 0.43 9.7 0.1 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family TFIIE_alpha PF02002.12 EMC84577.1 - 2.3e-34 117.0 0.6 3.9e-34 116.3 0.4 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 EMC84577.1 - 7.4e-34 115.5 4.2 2.3e-33 113.9 2.9 1.9 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 EMC84577.1 - 1.1e-11 43.8 0.9 2.2e-11 42.9 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.10 EMC84577.1 - 0.017 14.6 0.5 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DEAD PF00270.24 EMC84578.1 - 1e-19 70.6 0.0 1.1e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC84578.1 - 9.6e-12 44.5 0.0 2.4e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EMC84578.1 - 3.9e-09 36.5 0.2 1.3e-08 34.8 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF4332 PF14229.1 EMC84578.1 - 3e-05 23.9 0.0 9.6e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) ResIII PF04851.10 EMC84578.1 - 0.002 17.9 0.0 0.0073 16.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMC84578.1 - 0.016 15.3 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Methyltransf_10 PF05971.7 EMC84579.1 - 4.4e-80 269.0 0.0 6.7e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EMC84579.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC84579.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MANEC PF07502.9 EMC84579.1 - 0.0078 16.1 0.1 0.023 14.6 0.1 1.8 1 0 0 1 1 1 1 MANEC domain UPF0020 PF01170.13 EMC84579.1 - 0.037 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 EMC84579.1 - 0.052 12.6 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Death PF00531.17 EMC84580.1 - 2.8e-18 65.4 0.2 4.4e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.13 EMC84580.1 - 4e-16 58.8 49.5 3.3e-06 27.0 7.2 4.7 4 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region CTC1 PF15489.1 EMC84581.1 - 5.4e-50 169.8 0.1 7.1e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 CTC1 PF15489.1 EMC84582.1 - 1.5e-36 125.2 0.3 1.6e-36 125.1 0.2 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 DDRGK PF09756.4 EMC84582.1 - 0.079 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 DDRGK domain Ig_3 PF13927.1 EMC84583.1 - 1.1e-09 38.6 3.1 3.7e-05 24.1 0.6 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC84583.1 - 6.3e-09 35.7 0.1 2.4e-07 30.6 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 EMC84583.1 - 7.6e-08 32.1 0.4 0.00029 20.6 0.0 2.7 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84583.1 - 1.1e-07 31.8 0.3 0.0038 17.3 0.0 2.5 1 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC84583.1 - 0.00046 20.2 1.0 0.011 15.8 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Filamin PF00630.14 EMC84584.1 - 4.9e-22 78.3 0.1 8.1e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.19 EMC84584.1 - 7e-10 38.6 7.8 7e-10 38.6 5.4 3.1 4 0 0 4 4 4 1 B-box zinc finger Y_Y_Y PF07495.8 EMC84584.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain Laminin_II PF06009.7 EMC84584.1 - 0.16 11.7 0.4 0.28 10.9 0.3 1.3 1 0 0 1 1 1 0 Laminin Domain II F-box-like PF12937.2 EMC84585.1 - 2.1e-12 46.5 0.9 2.3e-12 46.4 0.6 1.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC84585.1 - 4.7e-07 29.2 0.1 5e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 F-box domain Latrophilin PF02354.11 EMC84586.1 - 1e-181 603.5 12.9 1.4e-181 603.0 8.9 1.2 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.11 EMC84586.1 - 1.7e-95 319.0 3.1 2.9e-95 318.3 2.2 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain DUF3497 PF12003.3 EMC84586.1 - 4.7e-72 241.8 0.9 6.9e-72 241.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) 7tm_2 PF00002.19 EMC84586.1 - 2.3e-67 226.6 17.4 3.6e-67 225.9 12.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Gal_Lectin PF02140.13 EMC84586.1 - 1.3e-23 83.1 0.9 3.5e-23 81.6 0.6 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.16 EMC84586.1 - 8.9e-16 57.7 7.1 2.2e-15 56.4 4.9 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 EMC84586.1 - 7.8e-09 35.4 1.4 2.3e-08 33.9 1.0 1.9 1 0 0 1 1 1 1 Hormone receptor domain DUF2602 PF10782.4 EMC84586.1 - 0.39 10.5 6.1 0.9 9.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2602) 7tm_2 PF00002.19 EMC84587.1 - 1.4e-56 191.3 27.6 2.2e-56 190.6 19.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3497 PF12003.3 EMC84587.1 - 1.8e-40 138.6 4.2 2.4e-40 138.2 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) GPS PF01825.16 EMC84587.1 - 3.7e-16 58.9 5.7 8.6e-16 57.7 3.9 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain EGF_CA PF07645.10 EMC84587.1 - 2.8e-05 24.0 7.0 2.8e-05 24.0 4.8 1.9 1 1 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.2 EMC84587.1 - 6.5e-05 22.8 4.7 6.5e-05 22.8 3.3 3.0 3 0 0 3 3 3 1 EGF domain cEGF PF12662.2 EMC84587.1 - 0.00029 20.4 2.1 0.00072 19.1 1.5 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF PF00008.22 EMC84587.1 - 0.0019 18.1 6.4 0.0019 18.1 4.4 2.6 3 0 0 3 3 3 1 EGF-like domain DUF1186 PF06685.6 EMC84587.1 - 0.03 13.5 0.0 0.071 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) FXa_inhibition PF14670.1 EMC84587.1 - 0.14 12.2 11.0 0.026 14.6 3.6 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Pox_A14 PF05767.7 EMC84587.1 - 1.3 8.9 9.0 0.53 10.2 2.2 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Vitellogenin_N PF01347.17 EMC84588.1 - 1e-149 499.6 2.0 1e-149 499.6 1.4 2.3 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.6 EMC84588.1 - 6.3e-69 232.1 1.0 6.3e-69 232.1 0.7 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1943) DUF1944 PF09175.5 EMC84588.1 - 1.6e-53 180.6 0.9 1.6e-53 180.6 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1944) VWD PF00094.20 EMC84588.1 - 5.4e-25 88.4 1.2 5.4e-25 88.4 0.8 2.9 3 0 0 3 3 3 1 von Willebrand factor type D domain HEAT_2 PF13646.1 EMC84588.1 - 0.00051 20.2 0.1 0.01 16.0 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats 7tm_1 PF00001.16 EMC84589.1 - 1.1e-25 90.2 16.3 1.1e-25 90.2 11.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 EMC84589.1 - 0.00019 21.2 3.4 0.00019 21.2 2.4 2.8 1 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa CopD PF05425.8 EMC84589.1 - 2.9 8.1 8.1 2 8.6 1.6 3.1 1 1 1 3 3 3 0 Copper resistance protein D PDZ PF00595.19 EMC84590.1 - 4e-08 33.3 0.1 6.7e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC84590.1 - 0.004 16.9 0.1 0.01 15.7 0.0 1.6 2 0 0 2 2 2 1 PDZ domain DUF3444 PF11926.3 EMC84590.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) DnaJ PF00226.26 EMC84591.1 - 1.7e-29 101.3 3.4 2.7e-29 100.7 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMC84591.1 - 2.3e-24 85.1 1.0 2.5e-21 75.3 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain KH_1 PF00013.24 EMC84592.1 - 3.2e-60 199.6 15.8 1e-17 63.5 0.0 4.6 4 1 0 4 4 4 4 KH domain KH_3 PF13014.1 EMC84592.1 - 1.5e-35 120.1 24.6 2.5e-11 42.9 0.5 5.3 4 1 0 4 4 4 4 KH domain KH_2 PF07650.12 EMC84592.1 - 3.4e-19 68.1 10.3 1.3e-05 24.6 0.2 4.4 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.5 EMC84592.1 - 4.8e-16 57.9 26.1 6.4e-10 38.3 7.1 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.1 EMC84592.1 - 9.3e-06 25.1 10.5 0.059 13.0 0.1 4.3 4 0 0 4 4 4 2 KH domain Secretin_N PF03958.12 EMC84592.1 - 0.00066 19.8 0.7 0.062 13.4 0.2 3.3 3 1 1 4 4 4 1 Bacterial type II/III secretion system short domain KH_5 PF13184.1 EMC84592.1 - 0.048 13.4 7.9 1.8 8.4 0.0 3.8 4 0 0 4 4 4 0 NusA-like KH domain I-set PF07679.11 EMC84593.1 - 1.7e-18 66.2 0.3 6.4e-18 64.4 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84593.1 - 2.1e-05 24.5 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC84593.1 - 0.00072 19.6 0.1 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain DUF2217 PF10265.4 EMC84594.1 - 1e-227 757.0 2.8 1.2e-227 756.8 1.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) UCH PF00443.24 EMC84595.1 - 4.1e-69 232.7 0.0 2.2e-67 226.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC84595.1 - 2.3e-28 99.5 0.0 1.8e-27 96.5 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EMC84595.1 - 1.6e-22 79.7 0.2 3e-13 49.9 0.0 3.4 3 0 0 3 3 3 2 DUSP domain zf-UBP PF02148.14 EMC84595.1 - 5.8e-16 58.3 10.4 5.8e-16 58.3 7.2 3.4 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein L_protein_N PF15518.1 EMC84595.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 L protein N-terminus Myb_DNA-binding PF00249.26 EMC84596.1 - 5.3e-10 39.1 0.2 1.1e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC84596.1 - 5.7e-07 29.5 0.1 1.9e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EMC84596.1 - 3.9e-05 23.1 7.4 3.9e-05 23.1 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type ADK PF00406.17 EMC84597.1 - 8e-78 259.5 0.0 4.9e-41 140.1 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 EMC84597.1 - 4.6e-21 75.8 0.0 7.6e-10 39.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EMC84597.1 - 4e-20 72.4 0.5 6.6e-08 32.9 0.0 3.5 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.1 EMC84597.1 - 4.9e-13 49.1 0.0 1.7e-05 24.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 EMC84597.1 - 3.2e-07 29.9 5.1 0.018 14.4 0.0 4.1 4 0 0 4 4 4 2 Thymidylate kinase Zeta_toxin PF06414.7 EMC84597.1 - 5.2e-07 28.9 0.4 0.014 14.5 0.0 2.8 2 2 0 2 2 2 2 Zeta toxin AAA PF00004.24 EMC84597.1 - 0.00013 22.1 0.3 0.19 11.8 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMC84597.1 - 0.00023 20.8 0.1 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EMC84597.1 - 0.0003 20.9 0.8 0.42 10.7 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EMC84597.1 - 0.00044 20.2 0.0 0.49 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain dNK PF01712.14 EMC84597.1 - 0.0014 18.5 0.1 0.35 10.7 0.0 2.5 2 0 0 2 2 2 1 Deoxynucleoside kinase Cytidylate_kin2 PF13189.1 EMC84597.1 - 0.0019 18.1 0.2 2 8.2 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_16 PF13191.1 EMC84597.1 - 0.0063 16.5 0.1 1.7 8.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain SKI PF01202.17 EMC84597.1 - 0.0094 15.8 0.7 19 5.0 0.0 3.9 4 0 0 4 4 4 0 Shikimate kinase SRP54 PF00448.17 EMC84597.1 - 0.022 14.2 0.5 6.9 6.0 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 EMC84597.1 - 0.037 13.0 0.1 4.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EMC84597.1 - 0.052 12.6 0.4 6 5.9 0.0 2.7 3 0 0 3 3 3 0 KaiC CobU PF02283.11 EMC84597.1 - 0.098 12.0 2.7 5.9 6.2 0.0 3.5 4 1 0 4 4 4 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Peptidase_C13 PF01650.13 EMC84598.1 - 3e-39 134.8 0.0 4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Glyco_transf_29 PF00777.13 EMC84599.1 - 6.4e-39 133.7 0.1 7.8e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_29 PF00777.13 EMC84600.1 - 3.9e-35 121.2 0.5 4.9e-35 120.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PIF1 PF05970.9 EMC84601.1 - 1e-22 80.6 0.0 2.1e-22 79.5 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase BTB PF00651.26 EMC84602.1 - 7.8e-27 93.4 0.3 1.4e-26 92.6 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC84602.1 - 1.2e-15 56.8 16.3 6.1e-07 29.4 3.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC84602.1 - 8.6e-12 44.6 20.7 2.8e-05 24.1 1.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC84602.1 - 2e-10 40.2 16.9 8.8e-05 22.5 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3342 PF11822.3 EMC84602.1 - 5.8e-05 22.3 0.2 5.8e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_2 PF12756.2 EMC84602.1 - 0.00028 20.9 6.5 0.042 13.9 0.0 3.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMC84602.1 - 0.00029 20.9 10.3 0.11 12.7 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC84602.1 - 0.0086 16.2 18.5 0.056 13.6 0.5 4.3 5 0 0 5 5 4 2 Zinc-finger of C2H2 type BTB_2 PF02214.17 EMC84602.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain zf-DNA_Pol PF08996.5 EMC84602.1 - 0.4 10.0 3.1 1.9 7.8 0.3 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Elf1 PF05129.8 EMC84602.1 - 0.43 10.3 3.0 0.35 10.5 0.5 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 EMC84602.1 - 0.77 9.5 16.6 2.1 8.2 0.2 3.6 2 1 0 2 2 2 0 BED zinc finger zf-trcl PF13451.1 EMC84602.1 - 1.3 8.7 4.8 2 8.1 1.1 2.6 2 1 1 3 3 3 0 Probable zinc-binding domain C1_1 PF00130.17 EMC84602.1 - 2.1 8.1 7.1 6.4 6.5 0.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Serpin PF00079.15 EMC84603.1 - 2.5e-116 388.8 0.2 2.8e-116 388.7 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) zf-RING_UBOX PF13445.1 EMC84604.1 - 8.4e-07 28.6 6.0 2.2e-06 27.2 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC84604.1 - 9.1e-06 25.4 5.1 2e-05 24.3 3.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC84604.1 - 9.9e-06 25.2 5.5 2.4e-05 24.0 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC84604.1 - 1.4e-05 24.7 3.8 2.8e-05 23.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84604.1 - 1.5e-05 24.8 6.6 3.2e-05 23.8 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84604.1 - 2.1e-05 24.1 6.4 4.4e-05 23.1 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC84604.1 - 0.00014 21.4 7.2 0.00028 20.4 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EMC84604.1 - 0.00014 21.4 3.3 0.00014 21.4 2.3 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 EMC84604.1 - 0.00095 19.0 1.3 0.002 18.0 0.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_4 PF14447.1 EMC84604.1 - 0.0035 16.8 5.2 0.022 14.3 0.6 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 EMC84604.1 - 0.046 13.4 1.5 0.1 12.3 1.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EMC84604.1 - 0.1 12.1 4.7 0.23 11.0 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EMC84604.1 - 0.13 12.0 0.9 0.29 10.9 0.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein 7tm_4 PF13853.1 EMC84605.1 - 5.8e-64 214.2 8.1 5.8e-64 214.2 5.6 2.5 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC84605.1 - 2.2e-26 92.5 15.8 2.8e-26 92.2 10.5 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC84605.1 - 0.07 12.2 11.0 0.12 11.5 7.3 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Yae1_N PF09811.4 EMC84607.1 - 1.4e-10 40.5 31.0 6.5 6.3 21.5 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal MACPF PF01823.14 EMC84608.1 - 6.7e-06 25.9 0.1 1.9e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 MAC/Perforin domain Glyco_hydro_31 PF01055.21 EMC84611.1 - 1.8e-09 36.9 0.0 2.1e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF148 PF02520.12 EMC84613.1 - 0.004 16.9 4.4 0.015 15.0 3.1 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF4279 PF14106.1 EMC84613.1 - 0.098 12.5 4.8 3.3 7.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) AAA_13 PF13166.1 EMC84613.1 - 0.14 10.5 16.6 0.2 10.0 11.5 1.2 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 EMC84613.1 - 0.56 9.7 30.7 0.68 9.4 0.1 4.6 3 1 2 5 5 5 0 Septum formation initiator TMF_TATA_bd PF12325.3 EMC84613.1 - 3.8 7.2 33.1 0.19 11.4 4.7 4.1 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 EMC84613.1 - 4 7.2 36.7 0.026 14.2 13.1 3.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EMC84613.1 - 6.2 6.6 39.9 1.3 8.8 7.4 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 EMC84613.1 - 6.2 6.8 6.5 38 4.2 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 EMC84613.1 - 8.3 6.2 19.9 2.7 7.7 0.3 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper Atg14 PF10186.4 EMC84613.1 - 8.7 5.1 27.4 4.8 6.0 6.3 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMEM51 PF15345.1 EMC84614.1 - 3e-89 298.7 0.0 3.6e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM61 PF15105.1 EMC84614.1 - 8e-05 22.2 0.5 0.0053 16.3 0.0 2.7 2 1 1 3 3 3 1 TMEM61 protein family RCR PF12273.3 EMC84614.1 - 0.015 15.8 0.1 0.032 14.7 0.0 1.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red FAM176 PF14851.1 EMC84614.1 - 0.046 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 FAM176 family WBP-1 PF11669.3 EMC84614.1 - 0.067 13.2 0.0 0.8 9.8 0.0 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 Myc_target_1 PF15179.1 EMC84614.1 - 0.071 12.6 0.4 0.2 11.1 0.2 1.8 1 1 0 1 1 1 0 Myc target protein 1 DUF465 PF04325.8 EMC84614.1 - 0.08 12.6 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF342 PF03961.8 EMC84615.1 - 0.014 13.8 1.4 0.016 13.6 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YqgF PF14639.1 EMC84615.1 - 0.016 14.8 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 MSG PF02349.10 EMC84615.1 - 0.11 12.5 8.1 0.11 12.4 1.6 2.3 1 1 1 2 2 2 0 Major surface glycoprotein DivIVA PF05103.8 EMC84615.1 - 0.52 10.3 6.9 0.69 9.9 1.3 2.1 2 0 0 2 2 2 0 DivIVA protein Cluap1 PF10234.4 EMC84615.1 - 0.66 9.1 5.4 0.19 10.8 0.7 1.8 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF724 PF05266.9 EMC84616.1 - 5.5 6.5 39.5 0.042 13.4 4.9 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF724) EF-hand_7 PF13499.1 EMC84617.1 - 0.00063 19.8 0.2 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC84617.1 - 0.00087 18.4 0.4 0.00087 18.4 0.3 2.3 3 0 0 3 3 3 1 EF hand Decorin_bind PF02352.10 EMC84617.1 - 0.027 14.4 5.0 0.13 12.2 1.2 2.1 2 0 0 2 2 2 0 Decorin binding protein EF-hand_8 PF13833.1 EMC84617.1 - 0.029 13.9 0.2 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair PcfJ PF14284.1 EMC84617.1 - 0.041 13.3 2.2 0.056 12.9 1.5 1.2 1 0 0 1 1 1 0 PcfJ-like protein AAA_23 PF13476.1 EMC84617.1 - 0.58 10.4 6.2 0.7 10.1 4.3 1.1 1 0 0 1 1 1 0 AAA domain FAM165 PF14981.1 EMC84617.1 - 0.72 9.3 4.4 1.4 8.5 3.0 1.5 1 0 0 1 1 1 0 FAM165 family Trypsin PF00089.21 EMC84618.1 - 7.4e-50 169.5 0.0 8.5e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMC84618.1 - 0.032 14.2 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain DUF1986 PF09342.6 EMC84618.1 - 0.046 12.9 0.1 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Peptidase_C14 PF00656.17 EMC84619.1 - 3.3e-43 148.1 0.0 4e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.16 EMC84619.1 - 5.2e-06 26.2 0.0 9.3e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain DnaJ PF00226.26 EMC84620.1 - 2.4e-11 43.1 0.4 6.8e-11 41.7 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 EMC84620.1 - 5.4e-10 38.8 0.0 5.4e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 EMC84620.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.1 EMC84620.1 - 0.026 14.6 0.5 16 5.6 0.0 4.2 4 0 0 4 4 4 0 Thioredoxin-like Thioredoxin_7 PF13899.1 EMC84620.1 - 0.14 12.2 0.2 0.85 9.6 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like Pkinase PF00069.20 EMC84621.1 - 4.5e-27 94.8 0.0 1.1e-26 93.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84621.1 - 8.1e-14 51.3 0.0 2.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC84621.1 - 0.0027 16.7 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC84621.1 - 0.0056 16.4 0.1 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC84621.1 - 0.055 12.8 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL dCMP_cyt_deam_1 PF00383.17 EMC84622.1 - 1.9e-17 62.7 0.1 2.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EMC84622.1 - 2.7e-10 40.2 0.3 1.3e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EMC84622.1 - 0.0009 18.6 0.9 0.61 9.4 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases GIDE PF12483.3 EMC84623.1 - 1.1e-23 83.3 0.0 2.1e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.1 EMC84623.1 - 3.2e-13 49.1 15.2 6.6e-13 48.1 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84623.1 - 6e-05 22.9 17.1 0.00011 22.1 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84623.1 - 0.00052 19.6 15.2 0.00097 18.8 10.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Vpu PF00558.14 EMC84623.1 - 0.037 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Vpu protein DUF4381 PF14316.1 EMC84623.1 - 0.041 14.0 0.1 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) COX6A PF02046.10 EMC84623.1 - 0.042 13.7 0.3 0.084 12.7 0.0 1.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa zf-RING_2 PF13639.1 EMC84623.1 - 0.15 11.8 18.4 0.042 13.6 10.6 1.7 2 0 0 2 2 2 0 Ring finger domain NicO PF03824.11 EMC84623.1 - 0.18 11.1 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Prok-RING_4 PF14447.1 EMC84623.1 - 0.21 11.1 9.7 0.6 9.6 6.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 VWA_3 PF13768.1 EMC84624.1 - 1.3e-32 112.6 0.0 2.6e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMC84624.1 - 1.3e-10 41.2 0.0 2.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC84624.1 - 2.8e-10 40.5 0.0 4.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EMC84624.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus UBX PF00789.15 EMC84625.1 - 9.6e-08 31.9 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Phospholip_A2_1 PF00068.14 EMC84626.1 - 1.6e-36 125.0 7.8 1.9e-36 124.7 5.4 1.1 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 EMC84626.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP1 BAMBI PF06211.7 EMC84626.1 - 7.1 6.6 11.4 1.7 8.6 0.6 2.4 2 1 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Phospholip_A2_1 PF00068.14 EMC84627.1 - 1.4e-33 115.5 11.6 1.5e-33 115.4 8.0 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.7 EMC84627.1 - 0.0011 18.8 11.3 0.054 13.4 7.8 2.3 1 1 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 EMC84627.1 - 0.0051 16.5 0.1 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 Parvovirus coat protein VP1 OTU PF02338.14 EMC84628.1 - 1.7e-11 44.7 0.5 4.6e-11 43.3 0.0 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease zf-RING_2 PF13639.1 EMC84629.1 - 3e-07 30.1 6.6 3e-07 30.1 4.6 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EMC84629.1 - 1e-06 28.2 8.0 2.8e-06 26.8 5.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84629.1 - 2.7e-06 26.9 5.8 8.2e-06 25.4 4.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC84629.1 - 1.1e-05 25.0 5.1 2.9e-05 23.6 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84629.1 - 1.5e-05 24.9 8.7 1.5e-05 24.9 6.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC84629.1 - 0.0017 18.1 6.6 0.0072 16.1 4.7 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1673 PF07895.6 EMC84629.1 - 0.0022 17.5 1.5 0.0035 16.9 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) zf-RING_UBOX PF13445.1 EMC84629.1 - 0.0035 17.0 2.5 0.0058 16.3 1.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMC84629.1 - 0.009 16.0 7.8 0.043 13.9 5.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger SdpI PF13630.1 EMC84629.1 - 0.09 12.4 2.8 0.24 11.1 1.4 2.0 2 0 0 2 2 2 0 SdpI/YhfL protein family zf-P11 PF03854.9 EMC84629.1 - 0.37 10.3 7.0 1.3 8.5 4.8 2.0 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 EMC84629.1 - 3.7 7.1 13.4 0.4 10.2 4.6 2.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF726 PF05277.7 EMC84630.1 - 1.9e-131 438.0 2.7 2.4e-131 437.7 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.7 EMC84630.1 - 0.00052 19.4 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EMC84630.1 - 0.00069 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase VirJ PF06057.6 EMC84630.1 - 0.013 15.3 0.0 0.067 12.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 EMC84630.1 - 0.021 14.4 0.0 0.06 12.9 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) DUF2566 PF10753.4 EMC84630.1 - 0.051 13.4 1.4 0.1 12.5 0.1 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2566) Pro-NT_NN PF07421.6 EMC84630.1 - 0.064 12.7 0.1 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor Cutinase PF01083.17 EMC84630.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.15 EMC84630.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.2 EMC84630.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0565 PF10561.4 EMC84630.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 5TM-5TMR_LYT PF07694.7 EMC84630.1 - 4.7 6.5 11.2 7.1 5.9 7.2 1.7 1 1 0 1 1 1 0 5TMR of 5TMR-LYT 7tm_1 PF00001.16 EMC84631.1 - 3.1e-69 232.9 10.0 4e-69 232.6 6.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC84631.1 - 4.9e-06 25.8 4.8 4.9e-06 25.8 3.4 2.3 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC84631.1 - 0.00059 19.0 7.9 0.00059 19.0 5.4 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DAN PF03045.10 EMC84632.1 - 4.2e-34 116.5 4.4 4.9e-34 116.3 3.1 1.0 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 EMC84632.1 - 3.7e-06 26.9 8.5 4.5e-06 26.6 5.9 1.1 1 0 0 1 1 1 1 Cystine-knot domain DUF543 PF04418.7 EMC84633.1 - 1.7e-17 63.1 1.3 1.7e-17 63.1 0.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF543) F_actin_cap_B PF01115.12 EMC84634.1 - 1.5e-111 371.3 0.0 1.8e-111 371.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit PQ-loop PF04193.9 EMC84635.1 - 3.8e-31 106.4 9.5 1.9e-18 65.7 0.8 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EMC84635.1 - 0.038 13.8 8.3 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Aldo_ket_red PF00248.16 EMC84636.1 - 2.1e-43 148.1 0.0 2.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1620 PF07774.8 EMC84637.1 - 3.9e-60 202.8 0.1 9.4e-60 201.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EMC84637.1 - 5.2e-13 49.0 0.6 7.6e-08 32.1 0.2 3.6 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EMC84637.1 - 2.6e-05 23.5 0.0 0.099 12.2 0.0 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat Filament PF00038.16 EMC84638.1 - 6e-23 81.7 18.3 1.5e-11 44.3 0.3 2.1 2 0 0 2 2 2 2 Intermediate filament protein Snapin_Pallidin PF14712.1 EMC84638.1 - 0.00041 20.5 2.1 0.00073 19.7 0.6 2.1 2 0 0 2 2 2 1 Snapin/Pallidin TPR_MLP1_2 PF07926.7 EMC84638.1 - 0.036 13.7 10.3 0.038 13.7 3.6 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 EMC84638.1 - 0.042 13.9 11.7 0.35 10.9 5.4 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 EMC84638.1 - 0.087 12.6 16.2 0.14 11.9 5.5 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EMC84638.1 - 0.097 11.8 10.9 0.025 13.7 4.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.13 EMC84638.1 - 0.13 11.7 8.7 0.094 12.2 3.1 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain FadA PF09403.5 EMC84638.1 - 0.64 10.0 9.8 0.22 11.5 3.5 2.3 2 0 0 2 2 2 0 Adhesion protein FadA DUF87 PF01935.12 EMC84638.1 - 1.1 9.0 6.9 0.19 11.4 1.7 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF87 Prefoldin PF02996.12 EMC84638.1 - 1.5 8.5 9.8 2 8.0 0.2 3.0 2 1 1 3 3 3 0 Prefoldin subunit CENP-H PF05837.7 EMC84638.1 - 4.5 7.5 12.4 1.6 8.9 2.0 3.2 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF2203 PF09969.4 EMC84638.1 - 7.9 6.7 7.8 0.79 9.9 1.3 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) PAX PF00292.13 EMC84639.1 - 9.6e-74 245.0 0.9 1.5e-73 244.4 0.6 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 EMC84639.1 - 8.9e-24 82.8 6.9 2.2e-23 81.5 4.8 1.7 1 0 0 1 1 1 1 Homeobox domain Pax7 PF12360.3 EMC84639.1 - 4.2e-21 74.9 8.5 1.1e-20 73.5 5.9 1.8 1 0 0 1 1 1 1 Paired box protein 7 HTH_23 PF13384.1 EMC84639.1 - 4.5e-06 26.1 1.0 0.00062 19.3 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EMC84639.1 - 1.3e-05 25.8 4.2 0.0087 16.8 0.0 2.9 2 1 0 2 2 2 2 Homeodomain-like domain Homeobox_KN PF05920.6 EMC84639.1 - 4.9e-05 22.9 0.4 0.00015 21.3 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_29 PF13551.1 EMC84639.1 - 6.6e-05 23.0 2.3 0.00073 19.6 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix Kelch_1 PF01344.20 EMC84640.1 - 4e-24 83.8 6.6 6.4e-10 38.4 0.0 4.2 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EMC84640.1 - 1.5e-18 66.0 9.1 4e-08 33.1 0.0 5.6 4 2 2 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EMC84640.1 - 9.1e-07 28.5 0.9 0.042 13.6 0.0 3.7 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC84640.1 - 2.5e-06 27.0 4.5 0.092 12.5 0.0 4.1 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EMC84640.1 - 0.00065 19.7 1.7 0.42 10.8 0.0 3.7 2 2 1 3 3 3 1 Galactose oxidase, central domain FLYWCH PF04500.11 EMC84640.1 - 0.00098 18.9 0.2 0.003 17.4 0.1 1.9 2 0 0 2 2 2 1 FLYWCH zinc finger domain Kelch_5 PF13854.1 EMC84640.1 - 0.0061 16.4 0.4 0.69 9.9 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Ig_2 PF13895.1 EMC84641.1 - 0.00012 22.1 0.0 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84641.1 - 0.00091 19.6 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC84641.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Cytochrom_D1 PF02239.11 EMC84642.1 - 0.027 12.7 0.0 0.038 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4573 PF15140.1 EMC84643.1 - 0.0042 16.7 20.5 0.0086 15.6 14.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) Amelogenin PF02948.10 EMC84643.1 - 1.5 9.4 40.5 97 3.5 28.1 3.1 1 1 0 1 1 1 0 Amelogenin Collagen PF01391.13 EMC84644.1 - 6.3e-28 96.1 51.5 2e-07 30.4 11.7 4.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PAD PF03068.10 EMC84645.1 - 7.2e-217 719.2 0.0 8.7e-217 719.0 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.5 EMC84645.1 - 3.1e-67 224.9 0.0 5e-67 224.2 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.5 EMC84645.1 - 1.3e-41 141.1 0.1 3e-41 139.9 0.0 1.6 2 0 0 2 2 2 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.10 EMC84646.1 - 1.7e-117 392.1 3.4 1.6e-72 244.1 0.0 2.0 2 0 0 2 2 2 2 Protein-arginine deiminase (PAD) PAD_M PF08527.5 EMC84647.1 - 3.3e-19 68.8 0.3 1.2e-18 67.0 0.1 1.9 2 0 0 2 2 2 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.5 EMC84647.1 - 2.4e-16 59.7 0.0 3.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain DUF3472 PF11958.3 EMC84647.1 - 0.014 15.7 0.4 0.02 15.2 0.1 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3472) PAD PF03068.10 EMC84648.1 - 1.3e-138 461.6 0.0 1.5e-138 461.4 0.0 1.0 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Fer2_3 PF13085.1 EMC84649.1 - 2e-31 108.0 0.0 3.5e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EMC84649.1 - 2e-05 24.8 1.2 2e-05 24.8 0.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMC84649.1 - 0.005 16.8 1.9 0.005 16.8 1.3 2.0 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EMC84649.1 - 0.0054 16.4 3.0 0.0094 15.6 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 EMC84649.1 - 0.01 16.2 1.1 0.01 16.2 0.7 2.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMC84649.1 - 0.02 15.1 0.9 0.02 15.1 0.6 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMC84649.1 - 0.029 14.1 0.4 0.029 14.1 0.3 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMC84649.1 - 2.6 8.1 12.4 1.6 8.8 3.3 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.2 EMC84649.1 - 8.3 7.0 10.5 1.1 9.7 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.2 EMC84649.1 - 9.4 6.7 10.7 12 6.4 3.7 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain E1-E2_ATPase PF00122.15 EMC84650.1 - 2.8e-38 131.2 0.0 3.8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EMC84650.1 - 0.00051 19.4 0.1 0.0013 18.1 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC84650.1 - 0.00089 19.4 0.0 0.0023 18.1 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC84650.1 - 0.009 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MARVEL PF01284.18 EMC84650.1 - 0.026 14.3 4.5 0.061 13.1 0.5 2.3 2 0 0 2 2 2 0 Membrane-associating domain Rootletin PF15035.1 EMC84651.1 - 2.1e-16 60.4 11.0 2.1e-16 60.4 7.6 2.7 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.5 EMC84651.1 - 0.0039 17.3 11.0 0.0039 17.3 7.6 1.5 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family AAA_15 PF13175.1 EMC84651.1 - 0.014 14.4 0.1 0.018 14.1 0.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain WXG100 PF06013.7 EMC84651.1 - 0.2 11.6 0.1 0.2 11.6 0.1 3.5 3 2 0 3 3 3 0 Proteins of 100 residues with WXG DUF1795 PF08786.6 EMC84651.1 - 0.3 10.9 4.1 0.48 10.2 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) DUF3250 PF11618.3 EMC84651.1 - 0.31 11.2 2.3 0.4 10.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3250) LemA PF04011.7 EMC84651.1 - 0.37 9.8 9.5 2.9 6.9 0.2 2.1 1 1 0 2 2 2 0 LemA family Med28 PF11594.3 EMC84651.1 - 1 9.6 11.8 0.33 11.2 2.9 2.3 1 1 1 2 2 2 0 Mediator complex subunit 28 PRKCSH-like PF12999.2 EMC84651.1 - 3.1 7.3 8.9 1.1 8.8 0.2 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like DUF342 PF03961.8 EMC84651.1 - 4.6 5.5 12.1 6.1 5.1 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1681 PF07933.9 EMC84652.1 - 1.1e-44 151.8 0.0 1.3e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) tRNA_anti-codon PF01336.20 EMC84652.1 - 0.15 11.9 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain SUZ PF12752.2 EMC84653.1 - 3.3e-13 49.9 0.1 3.3e-13 49.9 0.1 2.0 3 0 0 3 3 3 1 SUZ domain SUZ-C PF12901.2 EMC84653.1 - 4e-11 42.2 6.6 7.8e-11 41.3 4.6 1.5 1 0 0 1 1 1 1 SUZ-C motif Pkinase_Tyr PF07714.12 EMC84655.1 - 7.1e-97 323.5 0.0 8.5e-97 323.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC84655.1 - 4.3e-48 163.7 0.0 5.5e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 EMC84655.1 - 4.8e-15 55.6 0.4 7.7e-15 55.0 0.3 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain HSP20 PF00011.16 EMC84656.1 - 1.7e-16 59.9 0.0 2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EMC84656.1 - 0.09 13.3 0.0 0.14 12.6 0.0 1.3 1 1 0 1 1 1 0 CS domain Cyt_c_ox_IV PF12270.3 EMC84658.1 - 0.26 11.0 5.0 0.35 10.6 0.0 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV PH PF00169.24 EMC84659.1 - 2.1e-13 50.3 0.0 1.8e-11 44.1 0.0 2.9 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 EMC84659.1 - 0.00042 20.4 0.0 0.1 12.7 0.0 2.8 3 0 0 3 3 3 2 Pleckstrin homology domain bPH_3 PF14470.1 EMC84659.1 - 0.013 15.7 0.2 1.9 8.8 0.0 3.1 2 2 2 4 4 4 0 Bacterial PH domain SET PF00856.23 EMC84661.1 - 4.1e-19 69.4 0.1 4.8e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 SET domain KAT11 PF08214.6 EMC84662.1 - 3.7e-79 266.3 0.6 7.9e-79 265.2 0.4 1.5 1 0 0 1 1 1 1 Histone acetylation protein Creb_binding PF09030.5 EMC84662.1 - 8e-43 144.8 22.1 8e-43 144.8 15.3 11.8 6 3 5 13 13 13 1 Creb binding KIX PF02172.11 EMC84662.1 - 3.8e-42 142.2 0.9 1.3e-41 140.4 0.6 2.0 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.11 EMC84662.1 - 4.2e-35 119.5 66.4 8.7e-21 73.7 13.5 3.5 3 0 0 3 3 3 2 TAZ zinc finger DUF902 PF06001.8 EMC84662.1 - 3e-24 84.8 8.1 3e-24 84.8 5.6 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.20 EMC84662.1 - 1.9e-18 66.1 0.0 5e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.12 EMC84662.1 - 2.1e-14 52.7 14.2 2.1e-14 52.7 9.8 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type Npa1 PF11707.3 EMC84662.1 - 0.00026 20.1 0.0 0.00047 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal HSP90 PF00183.13 EMC84663.1 - 1.5e-79 267.8 5.3 1.3e-75 254.8 1.5 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 EMC84663.1 - 2.7e-13 49.7 0.1 1.1e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC84663.1 - 1.7e-08 34.1 0.1 3.6e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Slx4 PF09494.5 EMC84664.1 - 9.7e-18 63.6 0.0 1.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease Bravo_FIGEY PF13882.1 EMC84664.1 - 3.5 8.5 5.4 1.2 10.0 1.1 2.2 1 1 1 2 2 2 0 Bravo-like intracellular region zf-H2C2_2 PF13465.1 EMC84665.1 - 6.1e-79 256.6 64.5 2e-10 40.3 1.0 10.7 11 0 0 11 11 10 9 Zinc-finger double domain zf-C2H2 PF00096.21 EMC84665.1 - 1.6e-65 213.6 67.3 2.2e-07 30.8 0.4 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC84665.1 - 3.5e-39 131.5 52.8 7.5e-07 28.8 0.1 10.3 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMC84665.1 - 2.8e-34 114.9 60.0 0.0013 18.9 0.2 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC84665.1 - 3.3e-13 49.3 24.5 0.015 15.4 0.0 9.1 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EMC84665.1 - 2.6e-11 43.2 47.0 0.087 12.7 2.6 9.5 6 3 3 9 9 9 5 Zinc ribbon domain XPA_N PF01286.13 EMC84665.1 - 2.7e-11 42.9 32.1 3.1 7.5 0.1 10.1 10 0 0 10 10 10 2 XPA protein N-terminal C1_1 PF00130.17 EMC84665.1 - 2.7e-11 43.0 22.7 0.039 13.6 0.2 6.8 1 1 9 10 10 10 8 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.8 EMC84665.1 - 2e-10 39.9 33.3 1.7 8.1 0.1 10.0 10 0 0 10 10 10 3 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 EMC84665.1 - 8.9e-09 34.7 31.0 1.4 8.5 1.2 9.4 6 4 0 6 6 6 3 zinc-ribbon domain Imm-NTF2-2 PF15631.1 EMC84665.1 - 1.9e-08 34.1 0.0 8.7 6.4 0.0 7.5 2 1 7 9 9 9 0 NTF2 fold immunity protein Zn_ribbon_recom PF13408.1 EMC84665.1 - 7.3e-08 32.5 28.8 0.73 10.1 0.2 7.7 4 3 4 8 8 8 2 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.1 EMC84665.1 - 1.1e-07 31.3 29.6 1.7 8.4 1.2 9.2 6 4 0 6 6 6 2 zinc-ribbon domain zf-trcl PF13451.1 EMC84665.1 - 1.4e-06 27.8 37.4 0.61 9.7 0.1 9.7 9 1 0 9 9 9 1 Probable zinc-binding domain Elf1 PF05129.8 EMC84665.1 - 1.7e-06 27.6 25.5 0.17 11.5 0.8 5.8 1 1 5 6 6 6 4 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EMC84665.1 - 8.7e-06 25.4 54.4 0.057 13.2 2.5 7.9 4 3 3 8 8 8 5 Transposase zinc-ribbon domain CpXC PF14353.1 EMC84665.1 - 9.9e-06 25.5 27.8 9.3 6.2 0.6 9.5 7 2 0 8 8 8 0 CpXC protein TFIIS_C PF01096.13 EMC84665.1 - 0.00011 21.7 39.5 8.5 6.1 0.1 9.5 8 2 1 9 9 9 0 Transcription factor S-II (TFIIS) LIM PF00412.17 EMC84665.1 - 0.00034 20.6 36.0 1.6 8.8 0.8 7.7 2 2 6 8 8 8 3 LIM domain C1_4 PF07975.7 EMC84665.1 - 0.0014 18.6 38.5 0.45 10.5 2.2 7.8 1 1 7 9 9 9 4 TFIIH C1-like domain zf-AN1 PF01428.11 EMC84665.1 - 0.0018 18.0 39.8 18 5.2 0.1 9.9 9 1 1 10 10 10 0 AN1-like Zinc finger zinc_ribbon_2 PF13240.1 EMC84665.1 - 0.0033 16.8 36.2 0.11 12.0 0.6 7.7 5 2 3 8 8 8 1 zinc-ribbon domain FYDLN_acid PF09538.5 EMC84665.1 - 0.0079 16.7 21.5 32 5.1 0.2 8.5 1 1 6 7 7 7 0 Protein of unknown function (FYDLN_acid) C1_3 PF07649.7 EMC84665.1 - 0.0079 16.2 26.8 20 5.2 0.0 8.5 9 0 0 9 9 9 0 C1-like domain zf-Di19 PF05605.7 EMC84665.1 - 0.032 14.3 36.1 0.12 12.4 0.8 6.7 2 1 5 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding YhfH PF14149.1 EMC84665.1 - 0.043 13.6 39.7 13 5.7 0.3 9.7 10 0 0 10 10 10 0 YhfH-like protein HypA PF01155.14 EMC84665.1 - 0.052 13.2 32.1 7.1 6.3 1.0 5.8 1 1 4 5 5 5 0 Hydrogenase expression/synthesis hypA family Siva PF05458.7 EMC84665.1 - 0.059 12.9 17.0 0.37 10.3 1.5 3.8 1 1 2 4 4 4 0 Cd27 binding protein (Siva) BolA PF01722.13 EMC84665.1 - 0.066 13.1 18.3 0.64 10.0 0.1 5.1 2 1 2 4 4 4 0 BolA-like protein zf-met PF12874.2 EMC84665.1 - 0.14 12.4 0.5 0.14 12.4 0.3 9.5 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 EMC84665.1 - 0.2 11.3 38.1 3.8 7.2 0.2 9.7 10 0 0 10 10 10 0 LYAR-type C2HC zinc finger A2L_zn_ribbon PF08792.5 EMC84665.1 - 0.32 10.4 46.0 4.2 6.9 0.0 9.9 10 0 0 10 10 10 0 A2L zinc ribbon domain BRCA2 PF00634.13 EMC84665.1 - 1.1 8.6 19.0 12 5.3 0.1 5.5 5 0 0 5 5 5 0 BRCA2 repeat UPF0547 PF10571.4 EMC84665.1 - 1.9 8.2 42.6 7.5 6.3 0.2 9.3 10 0 0 10 10 10 0 Uncharacterised protein family UPF0547 Scramblase PF03803.10 EMC84665.1 - 3.2 6.7 4.7 9.5 5.2 0.2 2.6 1 1 1 3 3 3 0 Scramblase DUF2688 PF10892.3 EMC84665.1 - 5.1 6.8 27.2 22 4.8 0.1 8.7 8 2 2 10 10 10 0 Protein of unknown function (DUF2688) Mut7-C PF01927.11 EMC84665.1 - 7.8 6.4 26.9 3.1 7.7 1.7 5.4 1 1 4 5 5 5 0 Mut7-C RNAse domain Heme_oxygenase PF01126.15 EMC84667.1 - 1.6e-83 279.3 5.5 1.9e-83 279.0 3.8 1.1 1 0 0 1 1 1 1 Heme oxygenase zf-LITAF-like PF10601.4 EMC84668.1 - 9.1e-23 79.9 15.5 1.3e-22 79.4 10.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C3HC4_3 PF13920.1 EMC84671.1 - 1.2e-14 53.6 8.9 1.9e-14 53.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84671.1 - 1.2e-07 31.5 12.1 2e-07 30.8 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC84671.1 - 1.4e-05 24.8 11.9 2.4e-05 24.0 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC84671.1 - 0.00041 20.0 9.9 0.00074 19.2 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EMC84671.1 - 0.014 14.9 6.1 0.028 13.9 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EMC84671.1 - 0.95 9.1 8.0 1.7 8.3 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EMC84671.1 - 5.6 6.5 12.8 16 5.0 8.9 1.8 1 1 0 1 1 1 0 P-11 zinc finger DUF4507 PF14964.1 EMC84673.1 - 1.9e-127 425.0 0.4 2.2e-127 424.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Exo_endo_phos PF03372.18 EMC84674.1 - 1.7e-11 44.5 0.0 2e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMC84674.1 - 0.0051 16.4 0.1 0.024 14.2 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EMC84675.1 - 1e-09 38.7 0.1 1.2e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMC84675.1 - 0.014 14.9 0.0 0.059 12.9 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase ECH PF00378.15 EMC84676.1 - 1.7e-69 233.6 0.0 1.9e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Voltage_CLC PF00654.15 EMC84677.1 - 4.5e-94 315.4 24.7 4.5e-94 315.4 17.1 2.0 1 1 0 2 2 2 2 Voltage gated chloride channel FAM181 PF15238.1 EMC84678.1 - 8.8e-05 22.7 0.1 8.8e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 FAM181 LUC7 PF03194.10 EMC84679.1 - 3.5e-81 272.4 25.6 3.5e-81 272.4 17.7 2.2 2 1 0 2 2 2 1 LUC7 N_terminus Spore_III_AB PF09548.5 EMC84679.1 - 3.7 7.2 7.2 1.3 8.8 2.6 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FG-GAP PF01839.18 EMC84680.1 - 0.0052 16.4 0.1 0.11 12.2 0.1 2.5 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.1 EMC84680.1 - 0.037 14.3 0.1 3 8.2 0.0 2.8 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CSD PF00313.17 EMC84682.1 - 2.7e-13 49.4 0.0 3.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EMC84682.1 - 0.0038 16.6 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.18 EMC84682.1 - 0.049 13.7 0.0 0.078 13.0 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain PMM PF03332.8 EMC84683.1 - 9.4e-106 352.3 0.9 1.1e-105 352.1 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TMEM223 PF14640.1 EMC84684.1 - 3.6e-05 23.7 0.1 4.2e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 Aminotran_3 PF00202.16 EMC84685.1 - 3e-109 364.9 0.0 3.6e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Methyltransf_16 PF10294.4 EMC84686.1 - 1.5e-21 76.5 0.7 1.8e-19 69.8 0.5 2.2 1 1 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EMC84686.1 - 0.073 12.0 0.0 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMC84686.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EMC84686.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMC84686.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC84686.1 - 0.12 12.9 0.1 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Claudin_2 PF13903.1 EMC84687.1 - 1e-17 64.3 8.8 1.2e-17 64.1 6.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC84687.1 - 1.8e-11 43.9 2.8 2.8e-11 43.3 1.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family AA_permease_C PF13906.1 EMC84687.1 - 0.29 11.0 9.4 0.066 13.0 2.7 2.3 2 0 0 2 2 2 0 C-terminus of AA_permease DUF2244 PF10003.4 EMC84687.1 - 1.7 7.9 7.8 0.29 10.4 2.6 1.7 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) zf-DHHC PF01529.15 EMC84687.1 - 5.4 6.3 6.4 1.3 8.4 1.5 1.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase PsbN PF02468.10 EMC84687.1 - 7.4 6.2 7.4 2.8 7.6 2.6 2.2 1 1 1 2 2 2 0 Photosystem II reaction centre N protein (psbN) Tetraspannin PF00335.15 EMC84687.1 - 9.3 5.4 9.8 0.26 10.5 2.7 1.5 2 0 0 2 2 2 0 Tetraspanin family Fox-1_C PF12414.3 EMC84688.1 - 1.1e-41 141.1 24.8 2.6e-41 139.9 15.2 2.8 2 0 0 2 2 2 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 EMC84688.1 - 9e-19 66.8 0.1 1.7e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84688.1 - 2.4e-15 56.2 0.1 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC84688.1 - 4.3e-11 42.4 0.2 1.7e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC84688.1 - 0.065 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Tissue_fac PF01108.12 EMC84689.1 - 5.5e-21 74.3 0.0 2.5e-20 72.2 0.0 2.1 3 0 0 3 3 3 1 Tissue factor Interfer-bind PF09294.5 EMC84689.1 - 2.4e-11 43.5 0.2 5.6e-11 42.4 0.1 1.7 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 EMC84689.1 - 0.00018 21.5 0.2 0.42 10.7 0.0 2.6 2 1 0 2 2 2 2 Fibronectin type III domain GSG-1 PF07803.6 EMC84690.1 - 3.7e-54 181.3 0.9 6.4e-54 180.5 0.6 1.4 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 EMC84690.1 - 1.4e-10 41.1 4.6 3.1e-10 40.0 3.2 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC84690.1 - 2.6e-08 33.7 11.1 1.5e-05 24.7 7.7 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family CD20 PF04103.10 EMC84690.1 - 0.35 10.8 15.4 2 8.3 4.9 3.4 3 1 0 3 3 3 0 CD20-like family Rhomboid_SP PF12595.3 EMC84691.1 - 2e-106 354.2 1.4 2.9e-106 353.7 1.0 1.2 1 0 0 1 1 1 1 Rhomboid serine protease Rhomboid PF01694.17 EMC84691.1 - 3.1e-30 105.1 10.3 6.3e-30 104.1 7.1 1.5 1 0 0 1 1 1 1 Rhomboid family Herpes_UL56 PF04534.7 EMC84691.1 - 0.089 12.4 1.6 0.11 12.1 0.4 1.7 1 1 1 2 2 2 0 Herpesvirus UL56 protein Pur_DNA_glyco PF02245.11 EMC84692.1 - 1.1e-60 203.8 0.0 1.4e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) NPR3 PF03666.8 EMC84693.1 - 1.4e-84 284.2 13.0 2.1e-72 244.1 5.9 3.3 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EMC84693.1 - 0.00022 20.0 0.1 0.29 9.7 0.0 2.3 2 1 0 2 2 2 2 Nitrogen permease regulator 2 Globin PF00042.17 EMC84694.1 - 3.8e-29 101.2 0.0 5.6e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Globin Globin PF00042.17 EMC84696.1 - 2.5e-25 88.9 0.1 5e-25 87.9 0.0 1.5 2 0 0 2 2 2 1 Globin DUF3538 PF12057.3 EMC84696.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) Globin PF00042.17 EMC84697.1 - 1.7e-28 99.1 0.0 2.3e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Globin DIX PF00778.12 EMC84699.1 - 2e-31 107.5 0.8 3.6e-31 106.7 0.6 1.4 1 0 0 1 1 1 1 DIX domain RGS PF00615.14 EMC84699.1 - 2.1e-27 95.5 0.5 4.4e-27 94.5 0.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.5 EMC84699.1 - 1.2e-18 66.5 2.7 3.3e-18 65.0 1.9 1.9 1 0 0 1 1 1 1 Axin beta-catenin binding domain Thioredoxin_6 PF13848.1 EMC84700.1 - 2e-41 141.8 0.0 2.5e-32 112.1 0.0 3.1 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.15 EMC84700.1 - 5.8e-32 109.4 0.0 4.5e-23 80.9 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 EMC84700.1 - 2.2e-07 31.0 0.2 0.0037 17.4 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC84700.1 - 1.5e-06 28.1 0.0 1.1e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EMC84700.1 - 1.1e-05 25.4 0.0 0.00027 20.9 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EMC84700.1 - 0.0043 16.7 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EMC84700.1 - 0.022 14.2 0.0 0.073 12.6 0.0 1.8 1 0 0 1 1 1 0 Redoxin NMDAR2_C PF10565.4 EMC84701.1 - 3.2e-215 716.8 33.5 3.9e-215 716.5 23.2 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.21 EMC84701.1 - 5.1e-35 120.3 0.1 5.1e-35 120.3 0.1 2.1 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 EMC84701.1 - 3.7e-24 85.2 0.0 1.7e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 EMC84701.1 - 7.9e-20 70.6 0.4 1.7e-19 69.5 0.3 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 EMC84701.1 - 4.7e-08 32.2 0.2 8.1e-08 31.4 0.2 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region PMP22_Claudin PF00822.15 EMC84702.1 - 4.3e-49 166.3 16.3 4.8e-49 166.2 11.3 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC84702.1 - 6.1e-13 48.8 16.6 6.9e-13 48.6 10.9 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 EMC84702.1 - 0.0064 16.1 15.0 0.015 14.8 10.3 1.8 1 1 0 1 1 1 1 Amastin surface glycoprotein L_HGMIC_fpl PF10242.4 EMC84702.1 - 0.023 14.6 14.4 0.036 14.0 10.0 1.4 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.6 EMC84702.1 - 0.34 10.6 18.1 1 9.0 12.5 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Glucos_trans_II PF14264.1 EMC84702.1 - 0.94 8.4 16.1 0.36 9.7 5.9 2.3 1 1 1 2 2 2 0 Glucosyl transferase GtrII Fig1 PF12351.3 EMC84702.1 - 1.7 8.4 11.4 0.13 12.0 4.3 1.8 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Clc-like PF07062.7 EMC84702.1 - 2.5 7.2 18.7 2 7.6 6.8 2.1 1 1 1 2 2 2 0 Clc-like 7TMR-DISM_7TM PF07695.6 EMC84702.1 - 3 7.4 19.2 0.18 11.4 7.8 2.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4064 PF13273.1 EMC84702.1 - 3.1 7.9 12.2 8.1 6.6 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4401 PF14351.1 EMC84702.1 - 4.2 6.2 16.4 26 3.6 11.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF373 PF04123.8 EMC84702.1 - 4.4 6.2 8.7 6.6 5.6 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF202 PF02656.10 EMC84702.1 - 5.9 7.1 11.4 1.7 8.8 1.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) SUR7 PF06687.7 EMC84702.1 - 6.1 6.3 32.0 0.39 10.2 10.6 3.5 1 1 1 2 2 2 0 SUR7/PalI family Tektin PF03148.9 EMC84703.1 - 2.7e-135 450.8 23.1 3e-135 450.6 16.0 1.0 1 0 0 1 1 1 1 Tektin family Vps23_core PF09454.5 EMC84703.1 - 7.5e-05 22.2 1.8 0.053 13.1 0.2 2.7 2 0 0 2 2 2 2 Vps23 core domain NpwBP PF12622.2 EMC84703.1 - 0.042 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 mRNA biogenesis factor TBCA PF02970.11 EMC84703.1 - 0.063 13.3 16.5 2.6 8.1 1.1 4.3 3 1 1 4 4 4 0 Tubulin binding cofactor A L31 PF09784.4 EMC84703.1 - 0.49 10.4 5.0 1.7 8.7 0.1 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 ParA PF10609.4 EMC84704.1 - 1.2e-38 130.8 0.3 3.9e-38 129.1 0.2 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EMC84704.1 - 2.1e-07 30.5 0.0 2.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 EMC84704.1 - 0.041 13.4 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-C4_ClpX PF06689.8 EMC84704.1 - 2.7 7.5 5.9 0.85 9.1 0.6 2.5 3 0 0 3 3 3 0 ClpX C4-type zinc finger DUF846 PF05832.7 EMC84705.1 - 1.9e-52 176.7 12.6 2.4e-52 176.3 8.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) NACHT PF05729.7 EMC84707.1 - 6.4e-24 84.4 0.0 1.4e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 EMC84707.1 - 4.9e-18 63.1 8.8 0.00018 21.2 0.0 6.0 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.2 EMC84707.1 - 3.9e-16 58.2 15.1 5.5e-08 32.2 2.8 5.5 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC84707.1 - 9.4e-07 28.4 5.9 0.0024 17.5 1.1 4.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 EMC84707.1 - 8.1e-06 25.5 0.2 7e-05 22.4 0.1 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 EMC84707.1 - 4.5e-05 22.9 5.4 0.71 10.1 0.0 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC84707.1 - 0.00025 20.7 3.5 8.8 7.0 0.0 5.9 6 0 0 6 6 6 1 Leucine rich repeat UreE_C PF05194.7 EMC84707.1 - 0.0076 16.3 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 1 UreE urease accessory protein, C-terminal domain Dexa_ind PF15198.1 EMC84708.1 - 3e-43 145.6 10.2 3.3e-43 145.5 7.1 1.0 1 0 0 1 1 1 1 Dexamethasone-induced FPL PF09758.4 EMC84709.1 - 3e-52 176.3 10.7 6.2e-52 175.3 7.4 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein SOCS_box PF07525.11 EMC84710.1 - 1e-10 41.2 0.1 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 EMC84710.1 - 1.4e-10 40.8 0.0 3.4e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 SH2 domain zf-LITAF-like PF10601.4 EMC84714.1 - 1.5e-30 104.8 5.0 2e-30 104.4 3.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.1 EMC84714.1 - 0.0009 18.3 0.5 0.73 9.1 0.1 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zf-C4_Topoisom PF01396.14 EMC84714.1 - 0.0062 16.0 0.8 0.47 10.0 0.1 2.5 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1 PF03811.8 EMC84714.1 - 0.0081 15.6 1.2 0.89 9.0 0.2 2.4 2 0 0 2 2 2 1 InsA N-terminal domain UPF0547 PF10571.4 EMC84714.1 - 0.016 14.9 0.9 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.1 EMC84714.1 - 0.056 13.1 1.5 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMC84714.1 - 0.09 12.3 1.9 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Pheromone PF08015.6 EMC84714.1 - 0.13 13.0 0.0 0.22 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF1272 PF06906.6 EMC84714.1 - 0.96 9.3 6.8 4.4 7.2 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.1 EMC84714.1 - 4.7 6.9 9.9 8.3 6.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMC84714.1 - 6.7 6.3 8.1 23 4.6 2.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SNN_transmemb PF09049.5 EMC84715.1 - 6.8e-24 83.2 9.6 8.9e-24 82.8 6.6 1.2 1 0 0 1 1 1 1 Stannin transmembrane SNN_linker PF09050.5 EMC84715.1 - 4.7e-21 73.9 3.3 6.4e-21 73.5 2.3 1.2 1 0 0 1 1 1 1 Stannin unstructured linker SNN_cytoplasm PF09051.5 EMC84715.1 - 1.2e-20 72.8 0.4 1.6e-20 72.4 0.3 1.2 1 0 0 1 1 1 1 Stannin cytoplasmic CD34_antigen PF06365.7 EMC84715.1 - 0.074 12.7 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family OST-HTH PF12872.2 EMC84716.1 - 3.3e-53 177.4 2.1 3.7e-10 39.4 0.0 7.8 8 0 0 8 8 8 6 OST-HTH/LOTUS domain Limkain-b1 PF11608.3 EMC84716.1 - 2.2e-44 149.1 0.3 6e-44 147.7 0.2 1.7 1 0 0 1 1 1 1 Limkain b1 NYN PF01936.13 EMC84716.1 - 1.2e-18 67.8 0.0 2.8e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 NYN domain RRM_5 PF13893.1 EMC84716.1 - 1.4e-10 40.8 0.0 1.6e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC84716.1 - 1.7e-08 33.9 0.0 5.4e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84716.1 - 6.5e-06 26.0 0.0 0.0019 18.1 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Jnk-SapK_ap_N PF09744.4 EMC84716.1 - 0.033 14.1 0.1 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PAH PF02671.16 EMC84716.1 - 0.1 12.2 0.3 1.8 8.2 0.1 3.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat FlbD PF06289.6 EMC84716.1 - 0.16 11.3 1.9 1.7 8.0 0.2 2.7 2 0 0 2 2 2 0 Flagellar protein (FlbD) NUDE_C PF04880.8 EMC84717.1 - 5.8e-39 134.1 1.4 5.8e-39 134.1 0.9 2.2 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.5 EMC84717.1 - 0.0022 17.8 8.0 0.0022 17.8 5.5 4.0 2 1 1 3 3 3 1 DMPK coiled coil domain like WEMBL PF05701.6 EMC84717.1 - 0.21 10.0 30.7 0.29 9.5 21.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Pepsin-I3 PF06394.8 EMC84717.1 - 0.23 11.1 7.0 0.081 12.6 2.2 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF904 PF06005.7 EMC84717.1 - 0.25 11.6 35.7 0.56 10.5 6.2 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF904) DUF2009 PF09418.5 EMC84717.1 - 0.38 9.4 5.8 0.48 9.1 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) DUF3584 PF12128.3 EMC84717.1 - 0.49 7.6 30.0 0.67 7.2 20.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EMC84717.1 - 0.88 9.3 36.1 0.28 10.9 7.2 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Flagellin_N PF00669.15 EMC84717.1 - 0.93 9.2 8.5 1.4 8.6 1.9 2.5 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF972 PF06156.8 EMC84717.1 - 0.94 9.8 27.1 6.9 7.0 1.5 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EMC84717.1 - 2.4 7.2 4.2 6.7 5.7 0.6 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EMC84717.1 - 5.4 5.3 23.5 6.9 5.0 16.3 1.1 1 0 0 1 1 1 0 AAA domain FOP_dimer PF09398.5 EMC84718.1 - 5.3e-20 71.1 0.1 9.9e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH PF08513.6 EMC84718.1 - 1.3 8.9 4.5 0.29 10.9 0.8 1.7 2 0 0 2 2 2 0 LisH ABC_membrane PF00664.18 EMC84719.1 - 1.4e-85 287.0 41.6 1.2e-45 156.1 11.6 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC84719.1 - 1.5e-54 183.9 0.0 7.4e-29 100.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC84719.1 - 7.3e-10 38.4 1.2 0.00033 19.9 0.0 3.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EMC84719.1 - 1.9e-06 27.4 0.1 0.0027 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EMC84719.1 - 4.3e-06 26.9 0.2 3.5 7.4 0.4 4.5 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 EMC84719.1 - 6.6e-06 26.6 0.4 0.007 16.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EMC84719.1 - 8.8e-06 25.8 0.9 0.001 19.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EMC84719.1 - 9.4e-06 25.5 0.6 0.056 13.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMC84719.1 - 2e-05 23.8 0.8 0.0043 16.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EMC84719.1 - 9.8e-05 21.1 0.0 0.037 12.6 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 EMC84719.1 - 0.00034 19.7 0.1 0.016 14.3 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 EMC84719.1 - 0.005 17.1 0.3 2.1 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EMC84719.1 - 0.0089 15.8 4.1 0.022 14.5 0.1 2.8 3 0 0 3 3 2 1 Dynamin family AAA_29 PF13555.1 EMC84719.1 - 0.0096 15.4 3.5 0.92 9.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EMC84719.1 - 0.042 13.5 1.3 0.2 11.3 0.0 2.5 3 0 0 3 3 2 0 Archaeal ATPase DUF2370 PF10176.4 EMC84719.1 - 0.043 13.1 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) ATP-synt_ab PF00006.20 EMC84719.1 - 0.047 13.1 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EMC84719.1 - 0.064 14.0 2.9 8.6 7.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 EMC84719.1 - 0.082 13.0 3.2 5.4 7.1 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMC84719.1 - 0.095 12.1 0.4 12 5.2 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 EMC84719.1 - 0.098 11.5 0.5 2.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EMC84719.1 - 0.11 12.7 0.3 24 5.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 EMC84719.1 - 0.11 11.3 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 EMC84719.1 - 0.14 11.9 1.6 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMC84719.1 - 0.17 11.7 3.2 3.3 7.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 CarboxypepD_reg PF13620.1 EMC84720.1 - 6.7e-48 160.6 5.0 9.6e-10 38.3 0.3 9.8 9 1 0 9 9 9 7 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EMC84720.1 - 1.4e-25 88.8 2.7 0.0023 17.6 0.0 9.0 9 0 0 9 9 9 5 Cna protein B-type domain DUF4480 PF13715.1 EMC84720.1 - 3.5e-22 78.2 7.6 1.9e-06 27.8 0.4 9.2 9 1 1 10 10 9 5 Domain of unknown function (DUF4480) DUF2012 PF09430.5 EMC84720.1 - 3.7e-22 78.4 0.2 2.2e-07 30.7 0.0 7.5 7 1 1 8 8 8 4 Protein of unknown function (DUF2012) fn3_3 PF14686.1 EMC84720.1 - 7.5e-16 58.0 0.0 0.017 15.2 0.0 7.9 8 0 0 8 8 8 4 Polysaccharide lyase family 4, domain II DUF1416 PF07210.7 EMC84720.1 - 3.6e-07 29.7 0.5 0.98 9.0 0.0 6.1 6 1 0 7 7 7 1 Protein of unknown function (DUF1416) Y_Y_Y PF07495.8 EMC84720.1 - 3.9e-06 26.5 1.0 1.2 8.9 0.0 5.3 5 0 0 5 5 5 1 Y_Y_Y domain DUF2141 PF09912.4 EMC84720.1 - 0.001 18.7 0.0 1.5 8.5 0.0 4.8 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2141) phage_tail_N PF08400.5 EMC84720.1 - 0.001 18.8 0.1 3 7.5 0.0 5.3 7 1 0 7 7 7 1 Prophage tail fibre N-terminal DUF290 PF01060.18 EMC84720.1 - 0.002 18.1 0.1 50 3.9 0.0 5.1 5 0 0 5 5 5 0 Transthyretin-like family DUF3823 PF12866.2 EMC84720.1 - 0.01 15.3 0.0 1.2 8.6 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3823) DUF3244 PF11589.3 EMC84720.1 - 0.013 15.1 0.2 35 4.1 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3244) Cupredoxin_1 PF13473.1 EMC84720.1 - 0.1 12.5 0.1 4.2 7.3 0.0 3.6 2 1 1 3 3 3 0 Cupredoxin-like domain Ribosomal_S8 PF00410.14 EMC84721.1 - 1.7e-26 92.5 0.0 2.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Reticulon PF02453.12 EMC84722.1 - 7.8e-30 103.6 3.2 8.9e-30 103.5 2.2 1.0 1 0 0 1 1 1 1 Reticulon VirB3 PF05101.8 EMC84722.1 - 0.11 12.4 0.9 0.81 9.7 0.0 2.3 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein PI3_PI4_kinase PF00454.22 EMC84723.1 - 4e-52 177.0 0.0 1.1e-51 175.5 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EMC84723.1 - 2.7e-12 45.9 0.1 1.1e-11 43.9 0.0 2.2 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EMC84723.1 - 0.021 14.8 0.9 0.14 12.2 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Lectin_C PF00059.16 EMC84724.1 - 1.1e-18 67.7 0.3 1.4e-18 67.4 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain C2 PF00168.25 EMC84725.1 - 2.7e-40 136.1 0.1 7.8e-19 67.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 EMC84725.1 - 0.0018 17.9 0.7 0.069 12.7 0.1 2.6 1 1 1 2 2 2 2 C2 domain in Dock180 and Zizimin proteins COQ7 PF03232.8 EMC84727.1 - 1.4e-77 259.0 0.0 1.5e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EMC84727.1 - 0.024 14.9 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 Rubrerythrin PAH PF02671.16 EMC84727.1 - 0.034 13.7 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Paired amphipathic helix repeat Exotox-A_target PF09102.5 EMC84727.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Exotoxin A, targeting TMC PF07810.8 EMC84729.1 - 3.6e-39 133.6 0.4 3.6e-39 133.6 0.3 2.8 3 1 0 3 3 3 1 TMC domain LrgA PF03788.9 EMC84729.1 - 1.1 9.0 9.1 0.96 9.1 0.5 3.4 3 0 0 3 3 3 0 LrgA family SMAP PF15477.1 EMC84731.1 - 6.7e-19 67.9 1.3 1.2e-18 67.1 0.9 1.4 1 0 0 1 1 1 1 Small acidic protein family 7tm_4 PF13853.1 EMC84732.1 - 5.8e-41 139.6 14.2 5.8e-41 139.6 9.9 1.7 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC84732.1 - 1e-29 103.5 12.7 1.7e-29 102.7 8.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V-set PF07686.12 EMC84733.1 - 2.6e-16 59.5 0.0 2.9e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC84733.1 - 3.8e-08 33.0 0.0 6.7e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC84733.1 - 1.7e-06 28.0 0.0 0.00017 21.6 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC84733.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Pico_P2B PF01552.12 EMC84733.1 - 0.095 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Picornavirus 2B protein V-set PF07686.12 EMC84734.1 - 4.8e-12 45.7 0.0 5.9e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC84734.1 - 1.9e-05 24.6 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84734.1 - 0.00027 21.3 0.2 0.00067 20.1 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC84734.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC84734.1 - 0.0062 16.6 0.1 0.11 12.6 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC84736.1 - 1.6e-15 56.9 0.1 1.9e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC84736.1 - 5.7e-06 26.0 0.0 2.2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC84736.1 - 0.00013 22.0 0.0 0.0041 17.2 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC84736.1 - 0.0022 18.0 0.0 0.0032 17.5 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain AraC_binding_2 PF14525.1 EMC84736.1 - 0.074 12.6 0.2 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 AraC-binding-like domain V-set PF07686.12 EMC84737.1 - 2.3e-11 43.6 0.0 2.7e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC84737.1 - 4.7e-05 23.4 0.0 5.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84737.1 - 0.0003 21.2 0.2 0.00071 20.0 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC84737.1 - 0.0045 17.0 0.0 0.081 13.0 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC84737.1 - 0.0067 16.2 0.0 0.01 15.6 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 EMC84738.1 - 3.6e-11 42.9 0.0 3.9e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC84738.1 - 0.00067 19.7 0.0 0.00082 19.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC84738.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC84738.1 - 0.0086 16.1 0.1 0.015 15.3 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC84739.1 - 7.9e-10 38.6 0.0 9.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Formyl_trans_C PF02911.13 EMC84739.1 - 0.053 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Keratin PF02422.11 EMC84740.1 - 3.4e-42 142.3 12.5 3.7e-42 142.2 8.7 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 EMC84741.1 - 3.7e-14 52.5 0.2 4.2e-14 52.4 0.2 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC84741.1 - 3.1e-05 23.7 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84741.1 - 0.00031 20.8 0.6 0.0013 18.8 0.4 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC84741.1 - 0.0072 16.4 0.3 0.012 15.6 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84741.1 - 0.19 12.2 1.0 0.76 10.3 0.7 1.8 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC84742.1 - 1.3e-07 31.5 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Keratin PF02422.11 EMC84743.1 - 5.1e-29 100.1 1.9 5.3e-29 100.0 1.3 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 EMC84744.1 - 9.1e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Keratin PF02422.11 EMC84745.1 - 5e-36 122.5 21.3 5.7e-36 122.4 14.8 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC84746.1 - 4.7e-41 138.7 10.6 5.1e-41 138.5 7.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC84747.1 - 1.4e-24 85.8 4.2 1.5e-24 85.7 2.9 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 EMC84748.1 - 7.8e-10 38.6 0.0 9.4e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Keratin PF02422.11 EMC84749.1 - 1.6e-38 130.5 9.5 1.7e-38 130.4 6.6 1.0 1 0 0 1 1 1 1 Keratin MSSP PF03940.8 EMC84749.1 - 9.3 5.7 14.3 0.65 9.4 5.4 2.1 2 0 0 2 2 2 0 Male specific sperm protein Keratin PF02422.11 EMC84750.1 - 1.6e-36 124.1 20.6 1.8e-36 124.0 14.3 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 EMC84751.1 - 6e-09 35.7 0.0 7.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC84751.1 - 0.1 13.1 0.1 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC84752.1 - 2.1e-11 43.7 1.3 2.3e-11 43.5 0.9 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC84752.1 - 0.0015 18.5 0.6 0.0019 18.2 0.4 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC84752.1 - 0.0046 16.7 0.2 0.0071 16.1 0.1 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC84752.1 - 0.042 14.3 0.1 0.048 14.1 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC84753.1 - 1.2e-09 38.0 0.0 1.4e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.12 EMC84755.1 - 2e-07 30.8 0.0 2.2e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC84755.1 - 5.1e-06 26.2 0.0 5.3e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set_CD47 PF08204.6 EMC84755.1 - 0.0016 18.2 0.0 0.0017 18.1 0.0 1.0 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Ig_3 PF13927.1 EMC84755.1 - 0.0047 17.3 0.0 0.0064 16.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC84755.1 - 0.072 13.2 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.20 EMC84755.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain zf-C2H2 PF00096.21 EMC84757.1 - 0.12 12.7 0.1 0.12 12.7 0.0 4.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type 7tm_1 PF00001.16 EMC84758.1 - 1.5e-08 34.1 0.0 2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CUB PF00431.15 EMC84759.1 - 1.6e-17 63.5 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.12 EMC84759.1 - 7.7e-13 48.3 12.0 1.2e-12 47.7 8.3 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain Neur_chan_LBD PF02931.18 EMC84760.1 - 7.6e-55 185.4 0.2 1e-54 184.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC84760.1 - 6.1e-38 131.0 3.3 1.3e-36 126.6 2.3 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region NfeD PF01957.13 EMC84760.1 - 0.073 13.1 0.3 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Lig_chan PF00060.21 EMC84761.1 - 1.2e-60 203.4 0.1 2e-60 202.7 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 EMC84761.1 - 1.5e-49 168.7 0.1 2.5e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 EMC84761.1 - 4.4e-27 93.8 0.5 1e-26 92.6 0.4 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC84761.1 - 3.2e-26 91.9 0.0 6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 EMC84761.1 - 2.3e-06 27.1 0.0 5.7e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein FAM198 PF15051.1 EMC84762.1 - 1.6e-156 520.0 1.1 2e-156 519.7 0.8 1.1 1 0 0 1 1 1 1 FAM198 protein DUF1632 PF07857.7 EMC84763.1 - 4.5e-98 327.5 4.6 4.5e-98 327.5 3.2 1.8 1 1 1 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 EMC84763.1 - 1.1e-11 44.3 11.6 1.8e-10 40.3 2.2 2.4 2 0 0 2 2 2 2 Sugar transport protein Ribonuc_red_sm PF00268.16 EMC84763.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain LRR_8 PF13855.1 EMC84764.1 - 1.3e-42 143.3 27.6 1.1e-13 50.6 1.7 5.5 1 1 4 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.16 EMC84764.1 - 1.2e-27 96.6 17.1 1.8e-27 96.0 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.2 EMC84764.1 - 5.5e-27 92.9 32.2 1.3e-08 34.2 1.9 6.6 4 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC84764.1 - 1.8e-18 66.4 7.5 1.7e-08 34.2 0.1 2.5 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC84764.1 - 1.5e-12 45.7 27.3 0.041 13.8 0.1 10.1 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.1 EMC84764.1 - 6.8e-08 32.2 10.3 0.0083 15.7 0.2 3.6 1 1 2 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 EMC84764.1 - 2e-07 30.0 18.8 0.076 13.2 0.1 9.0 9 0 0 9 9 9 2 Leucine rich repeat Ldl_recept_a PF00057.13 EMC84764.1 - 1.3e-06 28.1 8.1 1.3e-06 28.1 5.6 2.1 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRR_6 PF13516.1 EMC84764.1 - 5.2e-06 25.9 22.0 0.2 11.8 0.2 8.7 8 2 1 9 9 9 2 Leucine Rich repeat LRRNT PF01462.13 EMC84764.1 - 5.2e-05 22.6 0.5 0.00018 20.9 0.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain ETF_QO PF05187.8 EMC84765.1 - 5.8e-45 151.7 0.0 1e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EMC84765.1 - 2.1e-10 40.0 0.5 8.6e-05 21.5 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC84765.1 - 4.3e-09 35.7 0.8 1.2e-05 24.3 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EMC84765.1 - 2.4e-07 30.0 0.0 2e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EMC84765.1 - 6.1e-07 29.3 0.1 3.8e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC84765.1 - 9.3e-06 25.6 0.1 2e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC84765.1 - 6.1e-05 22.1 0.1 8.5e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EMC84765.1 - 0.00012 21.3 0.0 0.00029 19.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMC84765.1 - 0.00013 20.6 0.5 0.00019 20.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EMC84765.1 - 0.00015 21.5 0.1 0.00037 20.3 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMC84765.1 - 0.00044 20.3 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC84765.1 - 0.0005 19.2 0.1 0.0008 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMC84765.1 - 0.005 15.5 0.1 0.038 12.6 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EMC84765.1 - 0.0062 16.9 0.2 0.72 10.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMC84765.1 - 0.013 14.3 0.2 0.021 13.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_7 PF12838.2 EMC84765.1 - 0.062 13.7 0.5 0.16 12.3 0.3 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.1 EMC84765.1 - 0.074 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pro_isomerase PF00160.16 EMC84766.1 - 2e-47 161.2 0.3 3.2e-47 160.6 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EMC84766.1 - 2.3e-19 68.8 4.4 4.3e-11 42.2 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMC84766.1 - 6.4e-12 44.5 1.6 9.3e-05 21.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC84766.1 - 1.8e-11 43.0 1.4 0.02 14.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC84766.1 - 8.1e-06 25.6 0.7 0.00058 19.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC84766.1 - 0.00029 20.4 0.1 1 9.3 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC84766.1 - 0.0015 18.9 0.9 0.6 10.8 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC84766.1 - 0.0028 18.3 0.8 0.013 16.1 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC84766.1 - 0.014 15.2 1.9 1.1 9.1 0.0 3.1 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EMC84766.1 - 0.06 13.1 0.4 3.4 7.6 0.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC84766.1 - 0.068 13.3 0.2 0.2 11.9 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMC84766.1 - 0.07 12.9 0.7 0.34 10.7 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC84766.1 - 0.16 12.1 3.4 0.18 11.9 0.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMC84766.1 - 0.25 11.6 2.8 0.98 9.8 0.7 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat FNIP_M PF14637.1 EMC84767.1 - 5.9e-89 297.6 1.1 1e-88 296.8 0.8 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 EMC84767.1 - 2.2e-69 232.6 0.4 5.9e-69 231.2 0.3 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 EMC84767.1 - 2.8e-35 121.6 0.1 2.8e-35 121.6 0.1 2.8 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus DUF4562 PF15123.1 EMC84768.1 - 2.1e-45 153.3 0.2 2.5e-45 153.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) RasGEF PF00617.14 EMC84770.1 - 2.5e-68 229.5 2.2 4e-68 228.8 1.5 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC84770.1 - 9.9e-18 64.1 0.2 2.8e-17 62.7 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.18 EMC84770.1 - 7.4e-12 45.5 0.1 1.9e-11 44.2 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 EMC84770.1 - 1.9e-10 40.7 0.0 5.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) cNMP_binding PF00027.24 EMC84770.1 - 6.8e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PDZ_2 PF13180.1 EMC84770.1 - 9e-05 22.2 0.0 0.00026 20.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain DUF1944 PF09175.5 EMC84770.1 - 0.022 14.4 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) Cullin PF00888.17 EMC84773.1 - 3e-27 95.4 0.0 3.4e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Cullin family APC10 PF03256.11 EMC84773.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) TPR_9 PF13371.1 EMC84773.1 - 0.34 10.7 3.1 0.59 10.0 1.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Prolamin_like PF05617.6 EMC84774.1 - 2.4e-05 24.3 12.0 0.43 10.7 0.0 6.0 1 1 4 5 5 5 3 Prolamin-like EB PF01683.13 EMC84774.1 - 3.4 7.8 7.9 4.3e+02 1.0 4.5 4.1 2 1 0 2 2 2 0 EB module FGGY_N PF00370.16 EMC84775.1 - 9.6e-74 247.7 0.0 1.4e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EMC84775.1 - 1.3e-66 223.9 0.5 2.4e-66 223.1 0.3 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4569 PF15133.1 EMC84776.1 - 1.5e-105 353.0 6.9 1.7e-105 352.8 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) UPF0731 PF14982.1 EMC84777.1 - 0.0022 17.8 0.3 0.62 10.0 0.2 2.2 2 0 0 2 2 2 2 UPF0731 family CUE PF02845.11 EMC84778.1 - 1e-09 37.6 0.2 3.1e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 CUE domain PRESAN PF09687.5 EMC84779.1 - 0.0024 17.9 3.6 0.0024 17.9 2.5 1.7 2 1 0 2 2 2 1 Plasmodium RESA N-terminal LRS4 PF10422.4 EMC84779.1 - 0.066 12.5 2.3 0.08 12.2 1.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Spectrin PF00435.16 EMC84780.1 - 2.6e-129 422.9 198.0 8.1e-19 67.8 2.7 17.2 15 1 1 17 17 17 15 Spectrin repeat CH PF00307.26 EMC84780.1 - 2.2e-34 117.7 5.1 2.5e-19 69.3 0.0 5.6 5 0 0 5 5 5 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC84780.1 - 8.3e-10 38.1 0.0 2.3e-05 23.9 0.0 4.0 3 0 0 3 3 3 2 CAMSAP CH domain Claudin_2 PF13903.1 EMC84781.1 - 1.8e-17 63.5 10.4 2.3e-17 63.2 7.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC84781.1 - 4.4e-06 26.4 5.8 5.5e-06 26.1 4.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.6 EMC84781.1 - 0.0025 17.5 9.0 0.0055 16.4 6.2 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Clc-like PF07062.7 EMC84781.1 - 0.006 15.8 10.4 0.025 13.8 0.3 2.1 1 1 1 2 2 2 2 Clc-like Sensor PF13796.1 EMC84781.1 - 0.0096 15.5 4.0 0.0096 15.5 2.7 2.0 1 1 1 2 2 2 1 Putative sensor Ost4 PF10215.4 EMC84781.1 - 0.056 12.9 0.4 0.17 11.4 0.3 1.9 1 0 0 1 1 1 0 Oligosaccaryltransferase ApoO PF09769.4 EMC84781.1 - 0.16 11.6 0.5 0.23 11.1 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein O DUF1282 PF06930.7 EMC84781.1 - 0.25 10.9 4.7 0.33 10.5 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Yip1 PF04893.12 EMC84781.1 - 1.1 8.7 14.9 2.1 7.7 10.3 1.5 1 1 0 1 1 1 0 Yip1 domain FtsX PF02687.16 EMC84781.1 - 2.4 7.9 9.6 0.04 13.6 0.9 2.1 2 1 0 2 2 2 0 FtsX-like permease family Oxidored_q3 PF00499.15 EMC84781.1 - 5.1 6.8 8.5 0.59 9.9 2.3 2.0 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 2TM PF13239.1 EMC84781.1 - 7 6.7 6.7 0.61 10.1 0.6 2.1 2 0 0 2 2 2 0 2TM domain DUF485 PF04341.7 EMC84781.1 - 7.7 6.3 9.7 0.39 10.4 2.0 2.1 1 1 0 2 2 2 0 Protein of unknown function, DUF485 Gag_p30 PF02093.11 EMC84783.1 - 8.5e-23 80.6 0.2 9.8e-23 80.4 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein DUF1992 PF09350.5 EMC84783.1 - 0.049 13.4 0.2 0.11 12.3 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1992) Interferon PF00143.14 EMC84784.1 - 4.8e-38 130.5 6.1 5.5e-38 130.3 4.2 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain GBP PF02263.14 EMC84784.1 - 3 6.8 6.3 2.6 7.0 0.7 2.0 1 1 0 2 2 2 0 Guanylate-binding protein, N-terminal domain PTPLA PF04387.9 EMC84785.1 - 3.5e-41 140.3 7.0 5.4e-41 139.7 4.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Prion_bPrPp PF11587.3 EMC84785.1 - 3.6 7.3 5.4 21 4.8 0.0 2.8 3 0 0 3 3 3 0 Major prion protein bPrPp - N terminal DUF3028 PF11229.3 EMC84786.1 - 1.2e-263 875.8 10.7 1.8e-263 875.2 7.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3028) DUF3730 PF12530.3 EMC84786.1 - 1.5e-65 221.3 23.6 1e-55 189.2 1.7 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3730) YEATS PF03366.11 EMC84787.1 - 3.4e-10 39.5 0.0 6.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 YEATS family PBP1_TM PF14812.1 EMC84787.1 - 0.029 14.6 1.0 0.029 14.6 0.7 3.7 3 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Na_Ca_ex PF01699.19 EMC84788.1 - 4.2e-58 194.9 40.6 2e-30 105.2 10.2 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1510 PF07423.6 EMC84788.1 - 0.18 11.1 0.0 0.18 11.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF1418 PF07214.7 EMC84788.1 - 1.7 8.3 4.8 43 3.8 1.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Ceramidase PF05875.7 EMC84789.1 - 1e-49 169.0 12.1 1.2e-49 168.8 8.4 1.0 1 0 0 1 1 1 1 Ceramidase Ribosomal_S6e PF01092.14 EMC84790.1 - 1.6e-64 215.2 0.1 1.6e-64 215.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e DENN PF02141.16 EMC84791.1 - 3.2e-61 206.3 3.7 6.2e-61 205.3 2.6 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EMC84791.1 - 1.5e-21 76.2 1.2 2.8e-21 75.3 0.8 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EMC84791.1 - 6.6e-11 42.0 0.4 2e-10 40.4 0.3 1.9 1 0 0 1 1 1 1 uDENN domain PPR_2 PF13041.1 EMC84791.1 - 1.5e-05 24.8 0.1 0.00043 20.1 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 EMC84791.1 - 0.0088 16.2 0.0 0.092 13.0 0.0 2.5 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.15 EMC84791.1 - 0.17 11.9 0.0 0.48 10.5 0.0 1.9 1 0 0 1 1 1 0 PPR repeat zf-C3HC4 PF00097.20 EMC84792.1 - 2.5e-10 39.8 8.4 4.4e-10 39.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC84792.1 - 1.3e-09 37.7 9.6 2.5e-09 36.8 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC84792.1 - 3.7e-09 36.4 9.6 3.7e-09 36.4 6.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC84792.1 - 5.6e-08 32.3 5.4 1.1e-07 31.4 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84792.1 - 4.3e-07 29.5 6.4 7.4e-07 28.7 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC84792.1 - 5.2e-05 23.2 6.7 9.5e-05 22.4 4.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC84792.1 - 0.0043 16.8 2.9 0.0082 15.9 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EMC84792.1 - 0.072 12.8 5.7 0.16 11.7 4.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC84792.1 - 0.11 12.3 11.1 0.21 11.4 7.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EMC84792.1 - 0.17 11.6 4.0 0.27 10.9 2.8 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Perilipin PF03036.11 EMC84793.1 - 6.4e-163 542.1 14.5 7.3e-163 541.9 10.0 1.0 1 0 0 1 1 1 1 Perilipin family Apc4 PF12896.2 EMC84793.1 - 0.059 12.6 4.6 1.5 8.0 0.1 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF2383 PF09537.5 EMC84793.1 - 0.26 11.5 6.1 3.6 7.8 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) Synuclein PF01387.12 EMC84793.1 - 1.5 8.7 13.1 1.9 8.4 6.9 2.4 2 0 0 2 2 2 0 Synuclein V-SNARE_C PF12352.3 EMC84793.1 - 2.8 8.0 6.8 3.1 7.9 1.4 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.6 EMC84793.1 - 3.9 7.9 8.2 14 6.1 1.1 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal YtxH PF12732.2 EMC84793.1 - 7.4 7.0 9.3 24 5.4 0.1 3.6 2 1 0 2 2 2 0 YtxH-like protein HAUS6_N PF14661.1 EMC84795.1 - 4.2e-39 134.3 0.6 4.2e-39 134.3 0.4 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus STOP PF05217.7 EMC84796.1 - 9.3e-20 71.2 28.1 9.8e-10 38.5 6.8 4.2 1 1 3 4 4 4 4 STOP protein I-set PF07679.11 EMC84797.1 - 4.4e-40 135.4 0.0 2.6e-12 46.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC84797.1 - 1.6e-27 95.4 0.3 7.5e-10 38.8 0.0 4.1 4 1 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 EMC84797.1 - 8.7e-16 58.1 1.6 4.1e-07 30.4 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain PLAC PF08686.6 EMC84797.1 - 9.1e-10 38.6 10.8 3e-09 36.9 7.5 2.0 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain V-set PF07686.12 EMC84797.1 - 3.4e-08 33.3 0.0 0.0059 16.4 0.0 4.4 3 2 0 3 3 3 2 Immunoglobulin V-set domain TSP_1 PF00090.14 EMC84797.1 - 1.6e-05 24.9 11.5 1.6e-05 24.9 8.0 5.7 4 1 1 5 5 5 3 Thrombospondin type 1 domain TSP_1 PF00090.14 EMC84798.1 - 4.4e-24 84.3 70.9 7.1e-06 26.0 2.3 7.8 6 2 0 6 6 6 5 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 EMC84798.1 - 0.0016 18.2 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Sad1_UNC PF07738.8 EMC84800.1 - 7.9e-34 116.3 0.0 8.6e-34 116.2 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal zf-HC5HC2H PF13771.1 EMC84801.1 - 1.3e-11 44.4 5.6 3.9e-11 42.9 3.9 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC84801.1 - 1.3e-07 31.6 2.0 3.6e-07 30.1 1.4 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain SH2 PF00017.19 EMC84803.1 - 1.7e-06 27.7 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Abhydrolase_6 PF12697.2 EMC84804.1 - 1.1e-33 117.1 0.2 1.3e-33 116.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC84804.1 - 2.1e-18 66.7 0.0 3.2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC84804.1 - 8.3e-11 41.8 0.0 1.1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC84804.1 - 1.6e-05 24.6 0.1 3.9e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EMC84804.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Arch_ATPase PF01637.13 EMC84804.1 - 0.013 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Thioesterase PF00975.15 EMC84804.1 - 0.016 15.4 0.8 0.088 13.0 0.1 2.2 2 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 EMC84804.1 - 0.032 13.8 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein RRP14 PF15459.1 EMC84804.1 - 0.15 12.1 0.5 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 RRP7 PF12923.2 EMC84805.1 - 2.8e-42 143.8 8.2 3.8e-42 143.4 5.7 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EMC84805.1 - 0.017 14.7 0.0 0.95 9.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A PF00476.15 EMC84805.1 - 0.036 12.6 0.5 0.048 12.2 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase family A RRM_6 PF14259.1 EMC84805.1 - 0.05 13.5 0.0 0.26 11.2 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Trans_reg_C PF00486.23 EMC84805.1 - 0.1 12.5 1.0 0.37 10.7 0.4 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Phage_GP20 PF06810.6 EMC84805.1 - 0.13 11.7 0.3 0.13 11.7 0.2 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.4 EMC84805.1 - 0.41 9.5 3.5 0.56 9.0 2.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RRM_1 PF00076.17 EMC84806.1 - 3.1e-10 39.5 0.0 7.9e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84806.1 - 8.2e-09 35.3 0.0 2.4e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC84806.1 - 6.7e-07 29.0 0.1 1.4e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Globin PF00042.17 EMC84807.1 - 3.4e-31 107.8 0.2 5.5e-31 107.1 0.1 1.4 2 0 0 2 2 2 1 Globin DUF3799 PF12684.2 EMC84807.1 - 0.0085 15.4 0.4 0.0094 15.3 0.3 1.1 1 0 0 1 1 1 1 PDDEXK-like domain of unknown function (DUF3799) Poty_PP PF08440.5 EMC84807.1 - 0.035 13.1 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein TPR_19 PF14559.1 EMC84808.1 - 7.9e-19 67.7 15.9 4.1e-05 23.8 0.1 6.3 6 1 1 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EMC84808.1 - 2.8e-14 52.9 24.9 7.3e-05 22.8 0.5 6.1 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EMC84808.1 - 3.2e-11 43.5 7.4 0.016 15.8 0.1 5.4 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC84808.1 - 3.3e-09 36.5 10.7 0.59 10.9 0.0 7.3 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC84808.1 - 4.3e-09 35.8 24.6 1.9e-07 30.6 0.2 5.2 6 2 1 7 7 5 3 TPR repeat TPR_2 PF07719.12 EMC84808.1 - 1.1e-08 34.2 29.9 0.03 14.2 0.2 8.8 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMC84808.1 - 6.8e-07 29.3 11.9 0.65 10.5 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC84808.1 - 2.7e-05 23.9 2.5 0.012 15.4 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC84808.1 - 4.5e-05 22.9 8.1 0.4 10.5 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC84808.1 - 6.6e-05 22.7 20.4 0.065 13.1 0.7 7.3 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC84808.1 - 0.00011 22.0 10.6 0.0076 16.3 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC84808.1 - 0.00032 20.1 21.9 0.01 15.4 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC84808.1 - 0.00042 19.9 10.5 2.8 7.9 0.2 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.15 EMC84808.1 - 0.0013 18.5 0.4 4.2 7.5 0.0 4.4 4 0 0 4 4 4 1 PPR repeat TPR_4 PF07721.9 EMC84808.1 - 0.0026 18.0 0.0 26 5.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 EMC84808.1 - 0.0069 16.3 0.3 15 5.6 0.0 3.9 3 1 1 4 4 3 0 PPR repeat family Fis1_TPR_C PF14853.1 EMC84808.1 - 0.037 13.8 4.7 0.33 10.8 0.1 3.6 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat FMN_red PF03358.10 EMC84808.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 NADPH-dependent FMN reductase TPR_10 PF13374.1 EMC84808.1 - 0.79 9.7 8.1 39 4.3 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Guanylate_cyc PF00211.15 EMC84809.1 - 1.2e-65 220.2 0.0 3.5e-65 218.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 EMC84809.1 - 2e-36 125.4 0.1 4.5e-36 124.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.23 EMC84809.1 - 4.7e-30 104.5 0.0 6.5e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.20 EMC84809.1 - 3e-29 101.9 0.2 9.3e-29 100.3 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Calc_CGRP_IAPP PF00214.14 EMC84809.1 - 0.053 13.5 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Peripla_BP_6 PF13458.1 EMC84809.1 - 0.27 10.5 0.0 0.47 9.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Phospholip_B PF04916.8 EMC84810.1 - 8.5e-171 568.8 0.7 9.6e-171 568.6 0.5 1.0 1 0 0 1 1 1 1 Phospholipase B DUF1992 PF09350.5 EMC84811.1 - 0.01 15.6 0.4 0.031 14.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) 7tm_2 PF00002.19 EMC84812.1 - 8.2e-83 277.2 12.9 1e-82 276.9 8.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC84812.1 - 5.2e-21 74.4 2.0 5.2e-21 74.4 1.4 2.3 2 0 0 2 2 2 1 Hormone receptor domain DUF1129 PF06570.6 EMC84812.1 - 0.065 12.5 1.4 0.17 11.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) PWWP PF00855.12 EMC84814.1 - 7.4e-12 45.3 0.6 7.4e-12 45.3 0.4 4.3 3 2 0 3 3 3 1 PWWP domain Bromodomain PF00439.20 EMC84814.1 - 7.9e-12 44.9 0.3 2e-11 43.6 0.2 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 EMC84814.1 - 0.00011 21.8 9.3 0.00011 21.8 6.4 4.5 3 2 1 4 4 4 1 PHD-finger zf-MYND PF01753.13 EMC84814.1 - 0.0022 17.8 21.8 0.0022 17.8 15.1 4.1 3 1 0 3 3 3 1 MYND finger Spore_III_AB PF09548.5 EMC84814.1 - 0.41 10.3 4.5 1 9.0 3.1 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Mitofilin PF09731.4 EMC84814.1 - 5.1 5.6 23.2 9.3 4.7 16.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AMP-binding PF00501.23 EMC84815.1 - 3.8e-74 249.5 0.1 1.6e-53 181.6 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 EMC84815.1 - 6.7e-13 49.2 2.2 1.2e-12 48.4 1.5 1.4 1 0 0 1 1 1 1 DMAP1-binding Domain La PF05383.12 EMC84817.1 - 2.4e-18 65.6 0.2 4.6e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_5 PF13893.1 EMC84817.1 - 0.00041 20.1 0.1 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC84817.1 - 0.00044 20.1 0.0 0.00099 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NUDIX PF00293.23 EMC84818.1 - 1e-25 89.9 0.0 1.4e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.27 EMC84819.1 - 2.8e-38 128.4 24.6 1.4e-08 34.2 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat HALZ PF02183.13 EMC84819.1 - 0.0024 17.5 0.3 0.005 16.5 0.2 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 EMC84819.1 - 0.085 13.2 0.9 0.18 12.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) A_deamin PF02137.13 EMC84820.1 - 6.8e-116 387.3 0.0 9.8e-116 386.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 EMC84820.1 - 6.7e-26 90.6 0.3 5.4e-12 46.1 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EMC84820.1 - 0.0045 17.2 0.9 1.4 9.2 0.0 2.9 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 Peptidase_M24 PF00557.19 EMC84822.1 - 3.5e-48 163.9 0.4 4.4e-48 163.5 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pyr_redox_dim PF02852.17 EMC84822.1 - 0.031 14.2 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain IF4E PF01652.13 EMC84823.1 - 2.8e-58 196.0 0.2 3.4e-58 195.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tetraspannin PF00335.15 EMC84824.1 - 4e-49 166.8 17.5 5.2e-49 166.5 12.1 1.1 1 0 0 1 1 1 1 Tetraspanin family zf-DHHC PF01529.15 EMC84824.1 - 0.14 11.5 1.5 0.48 9.7 0.0 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Arm PF00514.18 EMC84825.1 - 8.4e-33 111.0 17.7 3.2e-08 33.0 0.0 8.2 7 1 1 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC84825.1 - 1.4e-08 34.9 7.4 0.096 12.9 0.0 5.7 3 3 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 EMC84825.1 - 0.0074 16.7 11.0 2.4 8.7 0.1 5.3 7 0 0 7 7 7 2 HEAT-like repeat Nitr_red_bet_C PF14711.1 EMC84825.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal HEAT PF02985.17 EMC84825.1 - 0.11 12.6 3.1 5 7.4 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat V-ATPase_H_C PF11698.3 EMC84825.1 - 4.4 7.2 7.8 7.1 6.5 0.3 3.9 3 1 1 4 4 4 0 V-ATPase subunit H ZU5 PF00791.15 EMC84826.1 - 1.3e-37 127.6 0.1 2.5e-37 126.6 0.1 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.17 EMC84826.1 - 1.8e-13 50.0 0.0 3.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.11 EMC84826.1 - 2e-12 46.7 1.9 5.5e-11 42.1 0.1 3.2 3 0 0 3 3 3 1 Immunoglobulin I-set domain TSP_1 PF00090.14 EMC84826.1 - 6.4e-10 38.9 27.3 5.3e-08 32.8 5.5 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.1 EMC84826.1 - 2.3e-08 34.0 4.2 7e-07 29.2 0.0 4.0 3 2 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 EMC84826.1 - 3.1e-05 24.3 0.4 0.00099 19.5 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.12 EMC84826.1 - 0.00077 19.3 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain PTCRA PF15028.1 EMC84826.1 - 0.037 13.6 0.6 0.089 12.3 0.4 1.7 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Pkinase PF00069.20 EMC84827.1 - 7.8e-54 182.5 0.0 1.1e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84827.1 - 5.8e-38 130.4 0.0 7.9e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 EMC84827.1 - 1.4e-15 56.2 0.3 3.3e-15 55.0 0.2 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 EMC84827.1 - 2.5e-13 50.4 9.9 2.5e-13 50.4 6.9 1.8 2 0 0 2 2 2 1 Activin types I and II receptor domain LIM PF00412.17 EMC84828.1 - 1.4e-39 133.9 28.2 1.2e-13 50.8 2.8 3.4 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 EMC84828.1 - 3.3e-12 46.4 0.0 6.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC84828.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF1364 PF07102.7 EMC84828.1 - 2.5 8.0 6.8 14 5.6 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1364) 7tm_1 PF00001.16 EMC84829.1 - 1.8e-60 204.2 18.4 2.2e-60 203.9 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC84829.1 - 1.3e-17 63.8 14.3 1.7e-17 63.4 9.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC84829.1 - 1.2e-09 37.7 16.7 2.1e-09 36.9 11.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CcmH PF03918.9 EMC84829.1 - 0.053 12.5 0.1 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Baculo_11_kDa PF06143.6 EMC84829.1 - 8.8 5.7 6.9 1.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family GST_N PF02798.15 EMC84830.1 - 7.9e-22 77.2 0.1 3.1e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC84830.1 - 2.1e-08 34.0 0.1 3.4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC84830.1 - 6.2e-07 29.5 0.0 1.7e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC84830.1 - 3.5e-05 24.2 0.2 8.7e-05 22.9 0.1 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC84830.1 - 0.00022 21.1 0.0 0.00049 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC84830.1 - 0.00087 19.1 0.8 0.0077 16.1 0.4 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Synuclein PF01387.12 EMC84831.1 - 5.4e-60 201.0 17.2 6.1e-60 200.8 11.9 1.0 1 0 0 1 1 1 1 Synuclein MCP_N PF05581.7 EMC84831.1 - 0.18 11.9 0.8 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus C1q PF00386.16 EMC84833.1 - 1.5e-24 86.3 0.2 8e-24 84.0 0.0 2.4 2 0 0 2 2 2 1 C1q domain EMI PF07546.8 EMC84833.1 - 3.1e-15 56.3 5.3 3.1e-15 56.3 3.7 2.4 2 0 0 2 2 2 1 EMI domain EGF PF00008.22 EMC84833.1 - 6.9e-06 25.9 6.9 1.6e-05 24.7 4.8 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.10 EMC84833.1 - 0.2 11.6 5.9 0.66 10.0 4.1 1.8 1 0 0 1 1 1 0 Calcium-binding EGF domain FUSC PF04632.7 EMC84833.1 - 0.36 9.2 0.6 0.75 8.1 0.4 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family YvrJ PF12841.2 EMC84833.1 - 0.37 10.1 5.0 0.4 10.0 0.3 3.5 3 0 0 3 3 3 0 YvrJ protein family Laminin_II PF06009.7 EMC84833.1 - 6.8 6.4 47.5 0.05 13.3 3.5 7.6 5 3 4 9 9 9 0 Laminin Domain II TMF_DNA_bd PF12329.3 EMC84835.1 - 0.011 15.5 3.6 0.019 14.7 2.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ACP53EA PF06313.6 EMC84835.1 - 0.045 13.6 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Drosophila ACP53EA protein BRF1 PF07741.8 EMC84837.1 - 0.027 14.6 5.4 0.027 14.6 3.7 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain c-SKI_SMAD_bind PF08782.5 EMC84837.1 - 0.11 12.5 0.4 0.85 9.7 0.0 2.3 2 1 0 2 2 2 0 c-SKI Smad4 binding domain Peptidase_C1 PF00112.18 EMC84837.1 - 0.13 12.0 3.0 0.063 13.1 0.6 1.4 2 0 0 2 2 2 0 Papain family cysteine protease UPF0172 PF03665.8 EMC84837.1 - 0.17 11.3 1.2 0.33 10.3 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) HrpJ PF07201.6 EMC84837.1 - 1.8 8.5 14.4 0.17 11.9 5.5 2.1 1 1 0 2 2 2 0 HrpJ-like domain V_ATPase_I PF01496.14 EMC84837.1 - 2.3 5.9 4.3 2.5 5.8 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.1 EMC84837.1 - 4.7 7.5 6.9 4.5 7.5 3.8 1.5 1 1 0 1 1 1 0 Sine oculis-binding protein RBD-FIP PF09457.5 EMC84838.1 - 1.8e-21 75.6 4.7 1.8e-21 75.6 3.3 1.8 2 0 0 2 2 2 1 FIP domain C2 PF00168.25 EMC84838.1 - 4.5e-17 61.6 0.0 1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF2693 PF10902.3 EMC84838.1 - 0.11 12.4 0.9 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) Homeobox PF00046.24 EMC84839.1 - 6.1e-22 76.9 2.5 1.2e-21 76.0 1.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC84839.1 - 0.084 12.5 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Homeobox KN domain PDZ_2 PF13180.1 EMC84840.1 - 5e-09 35.9 0.1 1.6e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EMC84840.1 - 3.2e-07 30.4 0.2 9e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) C1_1 PF00130.17 EMC84840.1 - 2.4e-06 27.1 18.0 5.7e-06 25.9 12.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2404 PF10296.4 EMC84840.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) GRASP55_65 PF04495.9 EMC84840.1 - 0.0036 17.3 0.1 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain EFP_N PF08207.7 EMC84840.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Glyco_hydro_67N PF03648.9 EMC84840.1 - 0.2 11.7 0.6 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus MFS_1 PF07690.11 EMC84841.1 - 7.1e-46 156.5 35.4 6.3e-39 133.6 17.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC84841.1 - 3.6e-14 52.1 17.6 2.4e-09 36.3 0.9 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter LacY_symp PF01306.14 EMC84841.1 - 0.0026 16.3 16.3 0.0058 15.2 4.8 2.9 2 1 0 2 2 2 2 LacY proton/sugar symporter Ion_trans_2 PF07885.11 EMC84842.1 - 1.6e-30 104.6 22.9 9.1e-19 66.9 3.4 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 EMC84842.1 - 7.2e-05 22.1 4.2 7.2e-05 22.1 2.9 2.8 2 1 0 2 2 2 2 Ion transport protein DUF2842 PF11003.3 EMC84842.1 - 7.2 6.5 8.5 1.4 8.8 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) Homeobox PF00046.24 EMC84843.1 - 6.4e-13 48.1 1.6 9e-13 47.6 1.1 1.2 1 0 0 1 1 1 1 Homeobox domain HTH_AsnC-type PF13404.1 EMC84843.1 - 0.095 12.2 0.1 0.64 9.6 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MFMR PF07777.6 EMC84843.1 - 2.4 8.0 4.8 3.2 7.6 3.3 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR DUF3452 PF11934.3 EMC84844.1 - 1.4 8.1 13.3 0.49 9.7 6.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Enolase_C PF00113.17 EMC84845.1 - 4.6e-24 84.8 0.0 1.7e-23 83.0 0.0 1.9 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EMC84845.1 - 2.8e-13 49.9 0.3 2.5e-08 33.9 0.0 2.4 1 1 1 2 2 2 2 Enolase, N-terminal domain GEMIN8 PF15348.1 EMC84845.1 - 0.01 15.9 0.7 0.014 15.4 0.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Kin17_mid PF10357.4 EMC84845.1 - 0.11 12.0 1.9 0.2 11.3 1.1 1.6 1 1 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein HSP70 PF00012.15 EMC84846.1 - 5e-06 24.7 0.0 0.055 11.3 0.0 3.2 3 0 0 3 3 3 3 Hsp70 protein Exonuc_X-T_C PF08411.5 EMC84846.1 - 0.17 10.9 0.1 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal Lipase PF00151.14 EMC84847.1 - 1.5e-124 415.5 0.0 1.8e-124 415.2 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 EMC84847.1 - 4.3e-13 49.6 0.0 8.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 EMC84847.1 - 2.9e-07 30.5 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC84847.1 - 0.00031 20.4 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EMC84847.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase PF00151.14 EMC84848.1 - 1.8e-107 359.4 0.0 2.2e-107 359.1 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 EMC84848.1 - 9.2e-07 28.9 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC84848.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLAT PF01477.18 EMC84848.1 - 0.0031 17.8 0.2 0.029 14.7 0.1 2.2 2 0 0 2 2 2 1 PLAT/LH2 domain Myticin-prepro PF10690.4 EMC84848.1 - 0.027 14.5 0.5 0.05 13.6 0.3 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DUF900 PF05990.7 EMC84848.1 - 0.045 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase PF00151.14 EMC84849.1 - 5.7e-104 347.9 0.0 6.7e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 EMC84849.1 - 9.2e-07 29.2 0.1 1.6e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 EMC84849.1 - 1.3e-05 25.2 0.1 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC84849.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sec8_exocyst PF04048.9 EMC84850.1 - 0.019 14.5 1.4 0.019 14.5 0.9 3.0 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain Reo_sigmaC PF04582.7 EMC84850.1 - 0.069 12.3 5.5 0.15 11.2 0.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Serine_rich PF08824.5 EMC84850.1 - 0.39 10.4 9.1 1.6 8.4 6.0 2.1 1 1 1 2 2 2 0 Serine rich protein interaction domain TerB PF05099.8 EMC84850.1 - 1 9.1 6.2 0.84 9.3 0.1 2.9 3 0 0 3 3 3 0 Tellurite resistance protein TerB Syntaxin-6_N PF09177.6 EMC84850.1 - 1.4 9.3 21.1 0.14 12.5 4.4 3.4 1 1 3 4 4 4 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.4 EMC84850.1 - 2.6 7.8 42.7 0.049 13.4 15.8 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 USP8_interact PF08941.5 EMC84850.1 - 3.5 6.9 11.9 6.2 6.1 2.0 2.8 2 1 0 2 2 2 0 USP8 interacting Tropomyosin PF00261.15 EMC84850.1 - 5.9 5.9 39.7 10 5.1 27.4 1.5 1 1 0 1 1 1 0 Tropomyosin YojJ PF10372.4 EMC84850.1 - 6.9 6.6 9.2 36 4.3 0.5 3.7 2 2 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus Tropomyosin_1 PF12718.2 EMC84850.1 - 8.7 6.1 40.1 0.27 11.0 6.6 2.8 1 1 0 2 2 2 0 Tropomyosin like TPR_MLP1_2 PF07926.7 EMC84850.1 - 9.6 5.9 39.9 0.029 14.1 3.8 3.9 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein GDNF PF02351.11 EMC84851.1 - 9e-40 135.0 50.3 1.1e-18 67.5 4.1 3.4 4 0 0 4 4 4 3 GDNF/GAS1 domain Kelch_4 PF13418.1 EMC84852.1 - 1.1e-28 98.7 7.8 1.6e-05 24.5 0.1 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EMC84852.1 - 2.1e-24 84.7 10.7 0.0001 21.7 0.0 6.0 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 EMC84852.1 - 5.8e-24 83.5 19.6 1.3e-07 31.4 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EMC84852.1 - 1.8e-23 81.6 13.4 4.8e-05 23.3 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 EMC84852.1 - 2.2e-19 69.0 7.2 3.3e-05 23.9 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain PSI PF01437.20 EMC84852.1 - 1.4e-15 57.2 54.1 5.6e-11 42.4 6.0 8.6 8 1 0 8 8 8 5 Plexin repeat CUB PF00431.15 EMC84852.1 - 4.7e-12 45.9 0.0 1.3e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 CUB domain Kelch_2 PF07646.10 EMC84852.1 - 4.2e-11 42.1 12.6 0.032 14.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif EGF_2 PF07974.8 EMC84852.1 - 7.1e-05 22.8 10.0 7.1e-05 22.8 7.0 9.6 8 1 1 9 9 9 3 EGF-like domain Laminin_EGF PF00053.19 EMC84852.1 - 9.7e-05 22.2 18.3 9.7e-05 22.2 12.7 9.4 6 3 2 8 8 8 3 Laminin EGF-like (Domains III and V) RAI16-like PF10257.4 EMC84853.1 - 7.5e-132 439.5 6.7 9.4e-132 439.2 4.6 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Ecl1 PF12855.2 EMC84853.1 - 1.7 8.0 4.6 4.8 6.5 0.1 3.3 4 0 0 4 4 4 0 Life-span regulatory factor LIM PF00412.17 EMC84854.1 - 2.1e-42 142.9 44.1 3.9e-14 52.4 1.3 5.0 4 1 1 5 5 5 4 LIM domain VHP PF02209.14 EMC84854.1 - 2.2e-17 62.4 0.7 3.9e-17 61.6 0.5 1.4 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.24 EMC84855.1 - 5.8e-22 77.8 1.6 2e-10 40.8 0.0 2.8 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC84855.1 - 2.1e-07 31.1 5.5 0.016 15.4 0.1 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain IncA PF04156.9 EMC84855.1 - 8.9e-05 22.1 3.4 0.00024 20.7 2.3 1.7 1 0 0 1 1 1 1 IncA protein Striatin PF08232.7 EMC84855.1 - 0.0084 16.4 6.9 0.0084 16.4 4.8 2.4 2 0 0 2 2 2 1 Striatin family APG6 PF04111.7 EMC84855.1 - 0.033 13.2 9.3 0.065 12.2 6.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMC84855.1 - 0.055 11.3 2.5 0.09 10.6 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EMC84855.1 - 0.72 9.7 5.4 1.4 8.8 3.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EMC84855.1 - 3.3 6.0 8.0 5.3 5.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) VWA PF00092.23 EMC84856.1 - 1.3e-93 311.7 0.0 5.6e-39 133.6 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.1 EMC84856.1 - 5.2e-27 95.0 0.1 6.7e-09 36.0 0.1 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain EGF PF00008.22 EMC84856.1 - 1.4e-11 44.1 27.3 2.8e-06 27.1 8.3 2.6 2 0 0 2 2 2 2 EGF-like domain VWA_3 PF13768.1 EMC84856.1 - 2.9e-09 36.8 0.0 0.014 15.0 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain YjeF_N PF03853.10 EMC84856.1 - 0.12 11.9 0.4 4.9 6.7 0.2 2.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus EGF_2 PF07974.8 EMC84856.1 - 7.8 6.7 30.5 6.2 7.0 8.3 2.8 2 0 0 2 2 2 0 EGF-like domain TUDOR PF00567.19 EMC84857.1 - 1.3e-96 318.8 7.1 1.8e-36 124.6 0.0 4.6 4 1 0 4 4 4 3 Tudor domain SMN PF06003.7 EMC84857.1 - 3.1e-08 33.0 0.1 0.00031 19.9 0.0 2.5 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) Agenet PF05641.7 EMC84857.1 - 7.2e-07 29.2 0.5 0.3 11.2 0.1 4.0 3 0 0 3 3 3 2 Agenet domain DUF4537 PF15057.1 EMC84857.1 - 5.2e-06 26.2 0.0 0.31 10.8 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF4537) SNase PF00565.12 EMC84857.1 - 0.002 18.3 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 2 Staphylococcal nuclease homologue S1 PF00575.18 EMC84857.1 - 0.0065 16.5 0.9 54 3.9 0.0 4.3 4 0 0 4 4 4 0 S1 RNA binding domain TPR_MLP1_2 PF07926.7 EMC84858.1 - 7.4e-06 25.7 22.5 7.4e-06 25.7 15.6 8.3 3 1 6 9 9 9 5 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 EMC84858.1 - 0.0041 17.1 16.5 0.0041 17.1 11.4 9.0 3 1 6 9 9 9 2 DivIVA protein IncA PF04156.9 EMC84858.1 - 0.0071 15.9 30.1 0.0071 15.9 20.9 8.2 2 1 3 5 5 5 2 IncA protein Reo_sigmaC PF04582.7 EMC84858.1 - 0.75 8.9 28.3 0.1 11.7 0.6 4.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Toxin_21 PF08091.6 EMC84859.1 - 0.026 14.2 1.1 1.1 8.9 0.0 2.7 2 0 0 2 2 2 0 Spider insecticidal peptide 7tm_1 PF00001.16 EMC84860.1 - 8.5e-86 287.2 6.2 1.1e-85 286.9 4.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC84860.1 - 3.2e-16 59.2 2.7 4.5e-16 58.7 1.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC84860.1 - 1.8e-09 37.1 0.2 3.6e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC84860.1 - 2.6e-06 26.7 4.8 2.6e-06 26.7 3.3 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Vpu PF00558.14 EMC84860.1 - 1.7 8.2 3.4 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Vpu protein DRMBL PF07522.9 EMC84861.1 - 2.1e-34 117.8 0.7 1.1e-33 115.4 0.0 2.4 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EMC84861.1 - 6.5e-08 32.3 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EMC84861.1 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EMC84861.1 - 0.088 12.4 0.7 0.23 11.0 0.5 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PH_11 PF15413.1 EMC84862.1 - 4.8e-09 36.4 0.3 2e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EMC84862.1 - 9.1e-07 29.0 0.1 2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EMC84862.1 - 0.0031 17.5 0.2 0.2 11.7 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMC84862.1 - 0.011 15.5 0.2 0.11 12.4 0.0 2.4 2 1 0 2 2 2 0 PH domain Peptidase_C14 PF00656.17 EMC84863.1 - 1.8e-49 168.6 0.0 2.1e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Mut7-C PF01927.11 EMC84863.1 - 0.0087 16.0 0.1 0.035 14.0 0.0 1.9 2 0 0 2 2 2 1 Mut7-C RNAse domain TPP_enzyme_C PF02775.16 EMC84863.1 - 0.05 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Nebulin PF00880.13 EMC84864.1 - 1.4e-226 722.5 148.2 2.6e-09 36.2 0.2 42.1 41 1 0 41 41 41 41 Nebulin repeat DUF331 PF03889.8 EMC84864.1 - 0.028 13.6 2.3 5.3 6.4 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function Trypsin PF00089.21 EMC84865.1 - 1.5e-66 224.1 0.8 2e-66 223.7 0.6 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 EMC84865.1 - 1.1e-21 76.7 4.5 1.1e-21 76.7 3.1 2.3 2 0 0 2 2 2 1 Kringle domain EGF PF00008.22 EMC84865.1 - 1.4e-12 47.3 41.8 2.5e-07 30.5 5.4 4.7 4 0 0 4 4 4 2 EGF-like domain DUF1986 PF09342.6 EMC84865.1 - 8.5e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.8 EMC84865.1 - 0.00017 21.6 45.1 0.0098 16.0 5.0 4.8 4 0 0 4 4 4 2 EGF-like domain Trypsin_2 PF13365.1 EMC84865.1 - 0.0063 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Plasmod_Pvs28 PF06247.6 EMC84865.1 - 1.7 8.1 32.8 0.34 10.4 16.8 3.2 3 1 0 3 3 3 0 Plasmodium ookinete surface protein Pvs28 CENP-F_leu_zip PF10473.4 EMC84868.1 - 0.0077 16.0 1.3 0.0077 16.0 0.9 24.8 8 5 14 24 24 24 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 EMC84868.1 - 0.051 13.2 0.2 0.051 13.2 0.1 25.5 23 4 3 26 26 26 0 Homeobox associated leucine zipper TPR_11 PF13414.1 EMC84869.1 - 3.6e-45 151.4 36.1 3.9e-15 55.2 2.0 6.5 4 2 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 EMC84869.1 - 1.3e-38 127.7 14.7 3.2e-08 32.8 0.2 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMC84869.1 - 9.3e-38 126.3 20.9 2.3e-09 36.4 0.2 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 EMC84869.1 - 9.1e-31 103.3 14.9 1.4e-05 24.5 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat DUF1736 PF08409.6 EMC84869.1 - 5.5e-29 99.5 1.4 1.3e-28 98.3 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_16 PF13432.1 EMC84869.1 - 1.9e-27 95.2 5.1 0.00066 20.2 0.0 6.6 4 2 2 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMC84869.1 - 8.8e-27 91.0 27.0 2.6e-06 27.1 0.2 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 EMC84869.1 - 7.5e-24 83.4 16.4 1.1e-07 31.6 0.2 6.9 2 1 6 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 EMC84869.1 - 2.5e-21 75.7 13.9 3.6e-07 30.4 1.3 6.8 2 1 6 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMC84869.1 - 8.6e-19 66.3 8.0 0.00031 21.1 0.1 8.6 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMC84869.1 - 1.8e-10 40.5 15.9 0.098 13.1 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC84869.1 - 1.1e-08 35.1 6.2 0.084 13.0 0.2 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMC84869.1 - 1.1e-08 34.8 2.0 0.0018 18.1 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC84869.1 - 8.6e-07 28.3 9.4 2.9 7.9 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC84869.1 - 9.5e-06 25.3 15.0 2 8.4 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.5 EMC84869.1 - 0.00036 19.4 9.3 0.038 12.7 0.3 3.0 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) PMT_2 PF13231.1 EMC84869.1 - 0.00073 19.4 8.3 0.00073 19.4 5.7 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_15 PF13429.1 EMC84869.1 - 0.074 12.1 10.0 0.046 12.7 3.6 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC84869.1 - 0.089 12.6 3.1 14 5.6 0.0 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SCF PF02404.10 EMC84870.1 - 4.2e-153 508.2 1.7 4.7e-153 508.0 1.2 1.0 1 0 0 1 1 1 1 Stem cell factor DSPc PF00782.15 EMC84871.1 - 4.7e-43 145.9 0.0 6.7e-43 145.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EMC84871.1 - 5.9e-09 36.2 0.1 5.9e-07 29.8 0.1 2.8 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 EMC84871.1 - 7.8e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC84871.1 - 0.0069 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.27 EMC84872.1 - 3.2e-70 229.7 17.7 6.1e-13 48.1 0.8 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EMC84872.1 - 4e-09 36.4 0.1 1.8e-05 24.5 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC84872.1 - 2e-05 22.9 7.6 0.87 7.6 0.0 5.2 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 EMC84872.1 - 0.0064 15.7 0.2 5.6 6.3 0.0 3.0 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 EMC84872.1 - 0.016 13.5 0.0 0.25 9.6 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain Glycos_transf_2 PF00535.21 EMC84873.1 - 1.9e-31 109.0 0.0 3.6e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC84873.1 - 1.6e-24 86.3 0.0 2.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC84873.1 - 8e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMC84873.1 - 1.9e-06 27.1 0.0 7.3e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC84873.1 - 4.4e-06 26.0 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 EMC84873.1 - 0.014 15.7 0.0 0.036 14.4 0.0 1.7 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like E1-E2_ATPase PF00122.15 EMC84874.1 - 3e-56 190.0 0.4 6.1e-56 189.0 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC84874.1 - 4.5e-44 150.1 4.0 4.5e-44 150.1 2.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.3 EMC84874.1 - 1.4e-33 115.0 2.1 1e-15 57.8 0.7 2.7 1 1 1 2 2 2 2 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.21 EMC84874.1 - 4.5e-24 86.0 0.0 5.3e-23 82.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMC84874.1 - 1e-16 60.1 0.0 4.4e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC84874.1 - 1.1e-14 55.0 0.0 2.6e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC84874.1 - 1.8e-14 53.4 0.0 4.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC84874.1 - 7.9e-07 28.9 1.7 0.00019 21.0 0.3 2.8 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase LRR_8 PF13855.1 EMC84875.1 - 3.6e-22 77.8 8.1 1.8e-10 40.4 0.2 3.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC84875.1 - 1.3e-15 56.5 9.3 0.0011 18.5 0.0 4.5 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC84875.1 - 1.3e-12 45.8 10.3 0.38 10.9 0.0 7.2 7 0 0 7 7 7 4 Leucine Rich Repeat LRRNT PF01462.13 EMC84875.1 - 5.7e-07 28.8 4.9 1e-06 28.0 0.5 2.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 EMC84875.1 - 5.4e-06 26.1 0.1 0.00012 21.7 0.0 2.5 1 1 1 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC84875.1 - 6.1e-06 25.9 2.4 0.00045 19.8 0.8 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EMC84875.1 - 0.00028 20.6 7.2 24 5.3 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 EMC84875.1 - 0.0018 18.1 7.8 0.56 10.6 0.0 5.2 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 EMC84876.1 - 3e-34 116.5 27.0 3.6e-12 45.8 4.2 6.1 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EMC84876.1 - 4.5e-22 77.2 34.3 2e-06 27.3 1.1 7.7 4 3 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC84876.1 - 3.4e-19 65.8 26.4 0.1 12.7 0.0 11.3 10 1 1 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 EMC84876.1 - 9.9e-10 37.4 23.2 0.39 10.9 0.1 9.2 8 2 1 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 EMC84876.1 - 3e-08 32.5 23.5 8.7 7.0 0.1 10.5 11 0 0 11 11 11 1 Leucine rich repeat LRRNT PF01462.13 EMC84876.1 - 1.5e-05 24.3 2.0 1.5e-05 24.3 1.4 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 EMC84876.1 - 0.00011 21.8 2.4 0.0033 17.1 0.5 2.9 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC84876.1 - 0.00026 20.6 5.1 0.0059 16.1 1.5 3.0 1 1 2 3 3 3 1 Leucine-rich repeat CRT10 PF08728.5 EMC84876.1 - 0.055 11.4 0.0 0.079 10.9 0.0 1.2 1 0 0 1 1 1 0 CRT10 LRR_8 PF13855.1 EMC84877.1 - 1.8e-41 139.6 36.6 2.2e-13 49.7 2.8 5.2 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EMC84877.1 - 7.8e-28 95.5 34.6 1e-06 28.1 0.0 6.9 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC84877.1 - 1.3e-23 79.3 22.6 0.031 14.2 0.2 9.9 8 3 3 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 EMC84877.1 - 8.3e-13 46.9 29.6 0.098 12.7 0.0 9.8 9 1 1 10 10 10 6 Leucine Rich repeat LRR_7 PF13504.1 EMC84877.1 - 7.4e-12 43.4 26.4 0.27 11.6 0.0 9.5 10 0 0 10 10 10 4 Leucine rich repeat LRRNT PF01462.13 EMC84877.1 - 4.3e-08 32.4 2.2 4.3e-08 32.4 1.5 2.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 EMC84877.1 - 3.4e-07 30.0 3.0 0.00074 19.2 0.1 3.2 2 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC84877.1 - 0.00014 21.4 5.9 0.95 8.9 0.0 3.2 1 1 2 3 3 3 3 Leucine-rich repeat FNIP PF05725.7 EMC84877.1 - 0.11 12.5 14.4 1.5 8.8 0.3 4.5 3 2 1 4 4 4 0 FNIP Repeat DUF4292 PF14125.1 EMC84877.1 - 1.2 8.5 4.8 8.9 5.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4292) LRR_8 PF13855.1 EMC84878.1 - 5.4e-44 147.7 27.8 2.5e-14 52.7 4.3 4.8 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EMC84878.1 - 9.5e-28 95.3 26.1 2.7e-08 33.2 0.9 6.1 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC84878.1 - 8.1e-17 58.6 19.4 0.029 14.3 0.2 10.3 10 1 1 11 11 11 4 Leucine Rich Repeat LRR_5 PF13306.1 EMC84878.1 - 1.4e-12 47.4 1.5 1.7e-05 24.5 0.2 3.2 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRRNT PF01462.13 EMC84878.1 - 6.4e-10 38.2 5.4 6.4e-10 38.2 3.8 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EMC84878.1 - 9.5e-10 37.0 14.6 1 9.8 0.1 8.7 9 0 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 EMC84878.1 - 1.7e-08 33.6 22.6 0.036 14.1 0.0 8.9 10 0 0 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.1 EMC84878.1 - 5.8e-08 32.4 5.4 0.0053 16.3 1.1 3.2 1 1 2 3 3 3 3 Leucine-rich repeat FNIP PF05725.7 EMC84878.1 - 0.075 13.0 5.5 7.4 6.6 0.1 3.5 2 1 0 2 2 2 0 FNIP Repeat BTG PF07742.7 EMC84879.1 - 1.9e-32 111.2 0.0 2.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 BTG family RhoGEF PF00621.15 EMC84880.1 - 4.8e-18 65.6 2.4 4.8e-18 65.6 1.7 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EMC84880.1 - 0.0011 19.1 0.1 0.008 16.3 0.1 2.4 1 1 0 1 1 1 1 PH domain PH_5 PF15405.1 EMC84880.1 - 0.0027 17.6 6.8 0.0048 16.8 0.4 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_10 PF15411.1 EMC84880.1 - 0.013 15.6 0.3 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain FYVE PF01363.16 EMC84881.1 - 2e-20 72.4 10.5 2e-20 72.4 7.3 2.3 2 0 0 2 2 2 1 FYVE zinc finger CENP-F_leu_zip PF10473.4 EMC84881.1 - 0.00027 20.8 21.9 0.00027 20.8 15.2 15.1 4 2 10 14 14 14 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EMC84881.1 - 0.0016 18.0 282.0 0.013 15.0 42.3 11.8 1 1 7 8 8 8 4 Intermediate filament protein ERM PF00769.14 EMC84881.1 - 0.003 17.1 17.0 0.003 17.1 11.8 11.9 1 1 11 13 13 13 3 Ezrin/radixin/moesin family IBR PF01485.16 EMC84881.1 - 0.0033 17.2 4.7 0.018 14.9 3.2 2.3 1 0 0 1 1 1 1 IBR domain DUF4200 PF13863.1 EMC84881.1 - 0.007 16.3 11.2 0.007 16.3 7.8 16.7 3 1 12 18 18 18 3 Domain of unknown function (DUF4200) C1_4 PF07975.7 EMC84881.1 - 2.4 8.2 10.2 2.1 8.3 4.7 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain NUDIX PF00293.23 EMC84882.1 - 1.4e-15 57.1 0.2 1.7e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain UQ_con PF00179.21 EMC84883.1 - 1.2e-46 157.5 0.0 1.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC84883.1 - 7.7e-05 22.4 0.0 9.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EMC84883.1 - 0.0029 17.2 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EMC84883.1 - 0.031 14.1 0.0 0.038 13.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain MRP-S32 PF10210.4 EMC84884.1 - 2.3e-40 136.8 1.1 2.6e-40 136.6 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Pathogen_betaC1 PF09593.5 EMC84884.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein CARD PF00619.16 EMC84885.1 - 2.6e-17 62.4 0.1 4e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.17 EMC84885.1 - 1.9e-13 49.9 0.3 1.1e-11 44.3 0.1 2.3 2 0 0 2 2 2 2 Death domain Plexin_cytopl PF08337.7 EMC84886.1 - 2.5e-205 682.9 8.3 4.6e-205 682.0 5.8 1.4 1 1 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 EMC84886.1 - 5e-15 55.2 0.7 4e-07 29.9 0.0 2.9 2 0 0 2 2 2 2 IPT/TIG domain PSI PF01437.20 EMC84886.1 - 1.8e-09 37.6 9.9 1.8e-09 37.6 6.9 2.7 2 0 0 2 2 2 1 Plexin repeat DUF561 PF04481.7 EMC84886.1 - 0.0061 15.5 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF561) ABC2_membrane_3 PF12698.2 EMC84886.1 - 0.022 13.8 0.1 0.042 12.8 0.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Tmemb_cc2 PF10267.4 EMC84887.1 - 8.2e-172 571.2 14.3 9.4e-172 571.0 9.9 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Rootletin PF15035.1 EMC84887.1 - 0.0019 18.2 2.0 0.0019 18.2 1.4 3.7 3 1 0 4 4 4 2 Ciliary rootlet component, centrosome cohesion DUF2407_C PF13373.1 EMC84887.1 - 0.016 15.1 0.2 0.016 15.1 0.1 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain Orbi_NS3 PF01616.11 EMC84887.1 - 0.035 13.0 2.7 0.089 11.7 1.8 1.6 1 0 0 1 1 1 0 Orbivirus NS3 TMCO5 PF14992.1 EMC84887.1 - 0.23 10.5 20.9 0.65 9.0 4.4 2.4 2 0 0 2 2 2 0 TMCO5 family DUF4618 PF15397.1 EMC84887.1 - 0.34 10.2 21.4 0.066 12.5 5.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Effector_1 PF04518.7 EMC84887.1 - 0.8 8.6 16.9 0.085 11.8 3.4 2.3 2 0 0 2 2 2 0 Effector from type III secretion system COG2 PF06148.6 EMC84887.1 - 0.9 9.4 19.5 0.18 11.6 4.3 3.3 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CorA PF01544.13 EMC84887.1 - 0.98 8.3 14.8 0.77 8.7 0.8 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 EMC84887.1 - 3.1 7.6 12.0 1.3 8.8 2.6 3.1 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3782 PF12644.2 EMC84887.1 - 3.2 7.6 7.4 10 5.9 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) MbeB_N PF04837.7 EMC84887.1 - 3.4 7.8 10.0 2.2 8.4 0.6 3.2 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Phage_GPO PF05929.6 EMC84887.1 - 5.6 6.1 22.7 0.057 12.6 2.5 2.9 3 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase SEA PF01390.15 EMC84889.1 - 2.2e-13 49.8 0.5 1e-12 47.6 0.4 2.2 1 0 0 1 1 1 1 SEA domain Borrelia_P13 PF05628.7 EMC84889.1 - 0.62 9.8 2.8 19 5.0 0.1 2.8 2 0 0 2 2 2 0 Borrelia membrane protein P13 EGF_2 PF07974.8 EMC84889.1 - 5.3 7.2 25.4 0.076 13.1 0.7 3.1 3 0 0 3 3 3 0 EGF-like domain SEA PF01390.15 EMC84891.1 - 2e-15 56.3 0.3 4.7e-15 55.1 0.2 1.6 1 0 0 1 1 1 1 SEA domain TFIIA PF03153.8 EMC84891.1 - 0.038 13.8 8.2 0.038 13.8 5.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Latrophilin PF02354.11 EMC84892.1 - 9.7e-23 80.4 2.2 1e-22 80.3 1.5 1.0 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region Cadherin PF00028.12 EMC84894.1 - 3.2e-114 373.4 4.5 1.9e-22 79.3 0.1 7.5 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 EMC84894.1 - 3.3e-95 317.9 2.1 6.2e-95 317.0 1.5 1.5 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 EMC84894.1 - 3.1e-17 61.9 0.2 7.1e-09 35.1 0.0 4.9 5 0 0 5 5 5 3 Cadherin-like Y_Y_Y PF07495.8 EMC84894.1 - 0.074 12.8 0.0 2 8.2 0.0 3.4 3 0 0 3 3 3 0 Y_Y_Y domain He_PIG PF05345.7 EMC84894.1 - 0.27 11.3 8.4 2.1 8.4 0.0 5.0 5 1 0 5 5 5 0 Putative Ig domain Y_phosphatase PF00102.22 EMC84896.1 - 5e-11 42.3 0.0 4.1e-09 36.1 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EMC84896.1 - 1.8e-09 37.2 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain 7tm_1 PF00001.16 EMC84897.1 - 4.4e-34 117.7 34.1 8.7e-34 116.8 23.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YWFCY PF14293.1 EMC84897.1 - 0.53 10.1 9.3 2 8.3 0.1 3.3 3 0 0 3 3 3 0 YWFCY protein Peptidase_C65 PF10275.4 EMC84899.1 - 1.2e-52 178.7 0.0 1.4e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EMC84899.1 - 0.00018 22.0 0.0 0.00026 21.5 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Sad1_UNC PF07738.8 EMC84901.1 - 1.5e-33 115.4 0.5 3e-33 114.4 0.4 1.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal RNA_pol_Rpb1_2 PF00623.15 EMC84902.1 - 1.7e-15 57.3 0.0 2.5e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 wnt PF00110.14 EMC84903.1 - 3e-87 292.7 27.0 4.9e-87 292.0 18.7 1.3 1 1 0 1 1 1 1 wnt family Y_phosphatase PF00102.22 EMC84905.1 - 6.5e-149 493.6 6.6 6.1e-89 297.3 0.9 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Carb_anhydrase PF00194.16 EMC84905.1 - 5.3e-57 192.7 0.1 9.8e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.16 EMC84905.1 - 1.3e-12 47.6 1.0 4.4e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain DSPc PF00782.15 EMC84905.1 - 0.00051 19.6 0.1 0.018 14.5 0.0 3.4 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC84905.1 - 0.004 17.4 0.1 0.031 14.5 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC84905.1 - 0.03 14.3 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Saccharop_dh PF03435.13 EMC84906.1 - 8.3e-106 354.2 0.0 2e-105 352.9 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 EMC84906.1 - 3.3e-42 143.9 0.0 2.6e-41 141.0 0.0 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EMC84906.1 - 1.6e-26 92.9 0.8 2e-25 89.3 0.0 2.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain Semialdhyde_dh PF01118.19 EMC84906.1 - 0.0002 21.6 0.2 0.0007 19.8 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMC84906.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMC84906.1 - 0.0046 16.7 0.3 0.035 13.9 0.0 2.2 1 1 1 2 2 2 1 ThiF family DUF1041 PF06292.12 EMC84907.1 - 8.1e-30 103.1 1.7 2.3e-29 101.6 1.2 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.24 EMC84907.1 - 2.4e-06 27.6 0.0 5.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC84907.1 - 0.058 13.6 2.8 0.14 12.4 1.3 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain Na_sulph_symp PF00939.14 EMC84909.1 - 1.4e-85 288.0 29.3 1.6e-85 287.7 20.3 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMC84909.1 - 5.5e-06 25.1 23.3 0.00013 20.6 0.1 3.1 2 1 1 3 3 3 3 Citrate transporter ATP-synt_S1 PF05827.7 EMC84910.1 - 7e-39 133.8 0.7 7.9e-39 133.6 0.5 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.12 EMC84910.1 - 4e-07 29.4 0.1 6.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) COX5B PF01215.14 EMC84910.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb IQ PF00612.22 EMC84911.1 - 0.022 14.3 0.4 0.067 12.8 0.3 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif ETC_C1_NDUFA5 PF04716.9 EMC84912.1 - 1.5e-22 78.8 0.3 2.2e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region NEL PF14496.1 EMC84912.1 - 0.13 11.4 0.4 1.3 8.2 0.1 2.1 1 1 1 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting Ank_2 PF12796.2 EMC84913.1 - 7e-80 263.4 18.7 1.1e-16 60.9 0.9 5.9 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMC84913.1 - 6.2e-50 164.6 14.6 1.5e-05 24.5 0.4 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 EMC84913.1 - 1.2e-44 149.8 5.6 1.4e-09 38.1 0.0 8.6 6 3 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC84913.1 - 2.4e-40 132.5 6.5 0.00092 19.2 0.0 11.1 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 EMC84913.1 - 1.5e-36 123.5 12.1 2.4e-08 33.9 0.1 9.8 2 1 10 12 12 12 9 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC84913.1 - 4.7e-12 45.5 7.7 9.1e-12 44.6 5.3 1.5 1 0 0 1 1 1 1 SOCS box WH1 PF00568.18 EMC84914.1 - 3.8e-36 123.1 0.0 5.6e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 EMC84914.1 - 1.6e-17 63.6 0.1 4.6e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 EMC84914.1 - 5.6e-17 60.7 1.7 1e-07 31.3 0.1 2.6 2 0 0 2 2 2 2 WH2 motif PQQ PF01011.16 EMC84914.1 - 0.059 12.9 0.0 0.3 10.6 0.0 2.3 1 0 0 1 1 1 0 PQQ enzyme repeat Glyco_hydro_56 PF01630.13 EMC84915.1 - 4.5e-136 452.9 1.4 5.4e-136 452.6 1.0 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.22 EMC84915.1 - 0.0016 18.3 1.7 0.098 12.6 0.0 2.5 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.2 EMC84915.1 - 0.037 14.1 3.6 0.037 14.1 2.5 1.9 2 0 0 2 2 2 0 Human growth factor-like EGF TerD PF02342.13 EMC84915.1 - 0.044 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 TerD domain EGF_2 PF07974.8 EMC84915.1 - 2.9 8.1 10.0 1 9.5 1.5 2.5 2 0 0 2 2 2 0 EGF-like domain RNA_pol_Rpb1_R PF05001.8 EMC84916.1 - 5.3 7.4 32.9 8.2 6.8 0.2 6.6 5 1 0 5 5 5 0 RNA polymerase Rpb1 C-terminal repeat LIM PF00412.17 EMC84917.1 - 6.9e-62 205.3 63.4 2.8e-14 52.9 2.1 5.1 5 0 0 5 5 5 5 LIM domain DUF4428 PF14471.1 EMC84917.1 - 0.018 14.7 3.6 0.018 14.7 2.5 6.2 6 1 0 6 6 6 0 Domain of unknown function (DUF4428) Ran_BP1 PF00638.13 EMC84918.1 - 1.6e-191 625.4 19.9 5.4e-55 184.6 0.3 4.9 5 0 0 5 5 4 4 RanBP1 domain Pro_isomerase PF00160.16 EMC84918.1 - 1.5e-39 135.7 1.1 5.4e-39 133.8 0.7 2.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IR1-M PF12185.3 EMC84918.1 - 2.1e-36 123.4 5.3 1.3e-25 88.8 0.1 2.9 2 0 0 2 2 2 2 Nup358/RanBP2 E3 ligase domain zf-RanBP PF00641.13 EMC84918.1 - 1.6e-20 71.9 32.2 1.1e-08 33.9 3.0 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others WH1 PF00568.18 EMC84918.1 - 2.4e-17 62.6 7.4 0.00032 20.3 0.1 4.6 4 0 0 4 4 4 4 WH1 domain TPR_1 PF00515.23 EMC84918.1 - 2.1e-05 23.9 2.3 0.0011 18.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC84918.1 - 3.4e-05 23.4 3.0 0.00045 19.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMC84918.1 - 6.5e-05 22.5 1.1 0.0065 16.1 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 EMC84918.1 - 0.0029 17.2 2.2 0.067 13.0 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC84918.1 - 0.0072 16.8 0.1 1.1 10.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC84918.1 - 0.027 15.1 5.2 0.047 14.3 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC84918.1 - 0.056 13.7 1.2 26 5.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AMIN PF11741.3 EMC84918.1 - 0.092 12.7 1.1 28 4.7 0.0 3.6 4 0 0 4 4 3 0 AMIN domain DZR PF12773.2 EMC84918.1 - 0.73 9.7 16.7 0.75 9.6 5.8 2.7 2 0 0 2 2 2 0 Double zinc ribbon bZIP_1 PF00170.16 EMC84919.1 - 0.00095 19.0 2.7 0.00095 19.0 1.9 3.2 2 1 0 3 3 3 1 bZIP transcription factor HALZ PF02183.13 EMC84919.1 - 0.0018 17.9 1.6 0.0018 17.9 1.1 3.0 2 1 0 3 3 3 1 Homeobox associated leucine zipper NPV_P10 PF05531.7 EMC84919.1 - 0.0019 18.3 7.2 0.0022 18.1 0.7 2.8 2 1 1 3 3 2 1 Nucleopolyhedrovirus P10 protein Spc42p PF11544.3 EMC84919.1 - 0.0035 17.2 7.0 0.0035 17.2 4.8 2.7 2 1 0 2 2 2 1 Spindle pole body component Spc42p Syntaxin PF00804.20 EMC84919.1 - 0.0069 16.5 7.6 0.0069 16.5 5.3 1.9 2 0 0 2 2 2 1 Syntaxin DUF342 PF03961.8 EMC84919.1 - 0.051 11.9 11.4 0.066 11.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Tnp_P_element PF12017.3 EMC84919.1 - 0.07 12.3 3.3 0.098 11.8 2.0 1.5 1 1 0 1 1 1 0 Transposase protein APG6 PF04111.7 EMC84919.1 - 0.11 11.5 15.6 0.18 10.8 10.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.7 EMC84919.1 - 0.19 11.5 6.1 0.25 11.1 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EMC84919.1 - 0.25 10.2 17.3 0.33 9.8 11.7 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SPX PF03105.14 EMC84919.1 - 0.37 10.5 6.9 0.44 10.2 4.8 1.2 1 0 0 1 1 1 0 SPX domain Baculo_PEP_C PF04513.7 EMC84919.1 - 0.42 10.4 4.2 0.48 10.2 2.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.3 EMC84919.1 - 0.52 10.0 14.1 0.12 12.0 7.1 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF87 PF01935.12 EMC84919.1 - 0.6 9.8 8.3 0.23 11.2 3.5 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF87 Rootletin PF15035.1 EMC84919.1 - 0.74 9.7 19.2 1.9 8.4 13.4 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMPIT PF07851.8 EMC84919.1 - 0.77 8.7 17.4 0.029 13.4 4.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein DASH_Dam1 PF08653.5 EMC84919.1 - 1 9.2 3.0 6.5 6.6 0.2 2.8 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF3972 PF13118.1 EMC84919.1 - 1.2 9.2 11.9 0.23 11.5 5.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3972) Phage_GPO PF05929.6 EMC84919.1 - 1.5 8.0 8.6 2.1 7.5 6.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.14 EMC84919.1 - 2 6.1 16.7 16 3.2 11.5 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF883 PF05957.8 EMC84919.1 - 2.1 8.7 5.5 11 6.4 3.8 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3450 PF11932.3 EMC84919.1 - 3.6 6.7 17.0 0.1 11.8 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 EMC84919.1 - 3.6 7.4 21.6 1.7 8.4 10.3 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EMC84919.1 - 3.7 7.3 11.8 1.5 8.5 5.7 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF948 PF06103.6 EMC84919.1 - 5.3 6.9 6.4 72 3.3 4.3 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EMC84919.1 - 5.6 6.5 26.6 59 3.1 17.3 2.4 1 1 1 2 2 2 0 IncA protein Allexi_40kDa PF05549.6 EMC84919.1 - 6.4 5.9 10.1 2.2 7.4 4.5 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3571 PF12095.3 EMC84919.1 - 7.3 6.9 9.1 14 5.9 0.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) Sec20 PF03908.8 EMC84919.1 - 9.3 6.0 10.2 2.1 8.1 1.0 3.0 1 1 2 3 3 3 0 Sec20 Death PF00531.17 EMC84921.1 - 7.2e-05 22.4 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Death domain DUF4199 PF13858.1 EMC84921.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1510 PF07423.6 EMC84921.1 - 0.02 14.2 2.5 0.031 13.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TNFR_c6 PF00020.13 EMC84921.1 - 0.025 14.6 16.0 0.053 13.5 5.7 3.7 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region PIG-P PF08510.7 EMC84921.1 - 0.1 12.2 1.7 0.25 10.9 1.2 1.6 1 1 0 1 1 1 0 PIG-P DUF912 PF06024.7 EMC84921.1 - 0.47 10.5 5.6 0.2 11.7 0.4 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MIP-T3 PF10243.4 EMC84922.1 - 0.014 13.9 73.2 0.016 13.6 50.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAPS PF04499.10 EMC84922.1 - 0.19 10.3 24.8 0.21 10.1 17.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 EMC84922.1 - 0.21 10.0 23.1 0.29 9.6 16.0 1.2 1 0 0 1 1 1 0 Raftlin DUF4045 PF13254.1 EMC84922.1 - 0.42 9.8 30.6 0.49 9.6 21.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF912 PF06024.7 EMC84922.1 - 0.47 10.5 19.7 3.6e+03 -2.0 13.7 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF262 PF03235.9 EMC84922.1 - 0.48 10.3 19.2 0.56 10.1 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Suf PF05843.9 EMC84922.1 - 0.55 9.9 19.5 0.69 9.5 13.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 EMC84922.1 - 0.6 9.9 16.7 0.72 9.6 11.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1777 PF08648.7 EMC84922.1 - 0.82 9.3 36.4 1.4 8.6 25.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ycf1 PF05758.7 EMC84922.1 - 0.87 7.2 39.9 1 6.9 27.6 1.0 1 0 0 1 1 1 0 Ycf1 PA26 PF04636.8 EMC84922.1 - 0.87 8.2 18.5 1 7.9 12.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CAF-1_p150 PF11600.3 EMC84922.1 - 0.97 8.7 82.8 1.2 8.4 57.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nop14 PF04147.7 EMC84922.1 - 1.2 6.9 47.2 1.5 6.6 32.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 EMC84922.1 - 1.6 7.8 62.0 1.9 7.6 43.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2151 PF10221.4 EMC84922.1 - 2.6 6.0 27.6 2.9 5.9 19.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator FAM60A PF15396.1 EMC84922.1 - 3.3 7.3 26.8 4.7 6.8 18.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A U79_P34 PF03064.11 EMC84922.1 - 5.7 6.3 40.2 8.2 5.8 27.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 EMC84922.1 - 6.2 6.1 58.2 8.8 5.6 40.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SprA-related PF12118.3 EMC84922.1 - 6.6 5.9 38.3 9.2 5.4 26.5 1.2 1 0 0 1 1 1 0 SprA-related family PLRV_ORF5 PF01690.12 EMC84922.1 - 6.9 5.6 28.5 8 5.4 19.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Herpes_env PF01673.13 EMC84922.1 - 8.4 4.8 13.7 9.2 4.6 9.5 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Septin PF00735.13 EMC84923.1 - 5.7e-94 314.2 1.9 6.6e-94 314.0 1.3 1.0 1 0 0 1 1 1 1 Septin AAA_16 PF13191.1 EMC84923.1 - 7.1e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EMC84923.1 - 9.9e-05 22.2 0.0 0.00027 20.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC84923.1 - 0.00097 19.6 0.0 0.0033 17.8 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein AAA_15 PF13175.1 EMC84923.1 - 0.0021 17.1 1.3 0.0039 16.3 0.9 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC84923.1 - 0.0022 18.1 0.0 0.0048 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EMC84923.1 - 0.0025 17.2 1.1 1.3 8.3 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EMC84923.1 - 0.0042 16.5 0.1 0.0084 15.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EMC84923.1 - 0.0067 15.3 0.0 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Ras PF00071.17 EMC84923.1 - 0.014 14.7 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 0 Ras family G-alpha PF00503.15 EMC84923.1 - 0.016 13.8 3.3 0.11 11.2 2.3 2.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_10 PF12846.2 EMC84923.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EMC84923.1 - 0.027 14.7 0.5 0.04 14.2 0.3 1.6 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EMC84923.1 - 0.028 14.1 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EMC84923.1 - 0.031 13.7 1.1 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RHD3 PF05879.7 EMC84923.1 - 0.032 12.1 0.6 0.14 10.0 0.1 1.9 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) AAA_21 PF13304.1 EMC84923.1 - 0.06 13.2 3.0 0.35 10.8 2.0 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EMC84923.1 - 0.064 13.0 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EMC84923.1 - 0.086 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EMC84923.1 - 0.099 12.5 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC84923.1 - 0.48 10.7 2.3 1.5 9.1 0.3 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMC84923.1 - 1 9.6 5.4 10 6.3 3.8 2.2 1 1 0 1 1 1 0 AAA domain Smg4_UPF3 PF03467.10 EMC84924.1 - 1.5e-55 187.9 0.1 1.5e-55 187.9 0.1 2.2 3 0 0 3 3 3 1 Smg-4/UPF3 family FAST_1 PF06743.10 EMC84927.1 - 2.5e-20 71.9 1.4 3.7e-20 71.4 1.0 1.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 EMC84927.1 - 7e-08 32.7 0.0 4.5e-07 30.1 0.0 2.1 1 1 2 3 3 3 1 FAST kinase-like protein, subdomain 2 RAP PF08373.5 EMC84927.1 - 2.8e-05 23.7 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RAP domain DUF2359 PF10151.4 EMC84929.1 - 6.1e-05 21.7 0.0 8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2359) zf-H2C2_2 PF13465.1 EMC84930.1 - 2.7e-28 96.8 36.4 5.7e-10 38.9 1.2 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMC84930.1 - 1.5e-17 62.6 24.1 1.5e-05 24.9 2.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EMC84930.1 - 2.3e-16 59.0 32.2 0.00026 21.1 0.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC84930.1 - 2.8e-10 39.7 30.9 0.00045 20.3 0.7 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger GAGA PF09237.6 EMC84930.1 - 4.9e-05 22.8 10.5 0.0036 16.8 0.9 3.5 1 1 3 4 4 4 2 GAGA factor Ribosomal_L21e PF01157.13 EMC84930.1 - 0.059 13.1 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L21e Zn_Tnp_IS1595 PF12760.2 EMC84930.1 - 0.11 12.3 15.8 0.73 9.6 1.2 3.3 1 1 2 3 3 3 0 Transposase zinc-ribbon domain C1_1 PF00130.17 EMC84930.1 - 0.41 10.4 12.0 0.18 11.5 2.6 2.6 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 EMC84930.1 - 1.3 8.7 11.6 0.74 9.5 1.5 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Fer4_21 PF14697.1 EMC84930.1 - 1.8 8.4 9.1 1.1 9.1 0.3 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain DUF3505 PF12013.3 EMC84930.1 - 4.6 7.5 20.3 11 6.3 0.1 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 EMC84930.1 - 5.6 7.1 19.7 1.6 8.8 0.7 3.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1 PF03811.8 EMC84930.1 - 5.7 6.5 25.1 0.39 10.2 1.3 3.9 4 0 0 4 4 4 0 InsA N-terminal domain PP2C PF00481.16 EMC84931.1 - 1.3e-67 227.8 0.6 1.9e-55 188.0 0.2 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMC84931.1 - 2.9e-05 23.5 0.4 0.00034 20.0 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C TRAP_alpha PF03896.11 EMC84931.1 - 3.9 6.3 21.0 0.95 8.4 7.8 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.20 EMC84932.1 - 5.8e-26 91.1 1.0 1e-25 90.3 0.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC84932.1 - 2.9e-25 88.8 0.7 5.4e-25 87.9 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PRESAN PF09687.5 EMC84932.1 - 0.063 13.3 8.6 0.37 10.8 5.9 2.3 1 1 0 1 1 1 0 Plasmodium RESA N-terminal BCLP PF12304.3 EMC84933.1 - 5e-21 74.9 0.2 5.1e-21 74.9 0.2 1.0 1 0 0 1 1 1 1 Beta-casein like protein TPR_7 PF13176.1 EMC84934.1 - 0.029 14.1 10.8 5.2 7.1 0.0 6.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.15 EMC84934.1 - 0.033 13.7 6.2 0.83 9.2 0.2 4.1 3 1 1 4 4 4 0 Region in Clathrin and VPS PPR PF01535.15 EMC84934.1 - 0.051 13.5 0.9 78 3.5 0.1 4.5 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.1 EMC84934.1 - 0.067 13.8 16.6 1.9 9.3 0.0 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC84934.1 - 0.14 12.2 10.2 1.1 9.4 0.6 4.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EMC84934.1 - 0.19 11.6 11.0 3.8 7.4 0.0 5.4 4 2 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC84934.1 - 0.53 9.9 7.7 26 4.5 0.1 5.2 4 1 1 5 5 5 0 TPR repeat TPR_16 PF13432.1 EMC84934.1 - 0.63 10.7 12.1 7.4 7.3 2.4 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC84934.1 - 1.6 9.1 9.4 2.1 8.7 0.6 4.9 3 3 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC84934.1 - 3.7 7.3 12.2 16 5.3 0.3 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat PID PF00640.18 EMC84935.1 - 3.4e-21 75.6 0.2 3.9e-21 75.5 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.1 EMC84935.1 - 1.7e-13 50.5 0.2 2.1e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 EMC84935.1 - 1.6e-10 40.9 0.1 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain fn3 PF00041.16 EMC84936.1 - 4.5e-11 42.7 0.7 1e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain DUF3357 PF11837.3 EMC84936.1 - 0.062 13.1 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) zf-C2H2_jaz PF12171.3 EMC84937.1 - 2e-08 34.1 14.5 0.00088 19.3 0.4 4.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMC84937.1 - 1.1e-06 28.5 37.1 0.0023 18.1 2.5 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC84937.1 - 1.6e-06 28.0 25.7 0.11 12.8 1.1 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger CpXC PF14353.1 EMC84937.1 - 2.1e-06 27.7 10.6 0.031 14.2 0.0 3.9 3 1 0 3 3 3 2 CpXC protein zf-FCS PF06467.9 EMC84937.1 - 2.9e-05 23.5 5.4 0.022 14.3 0.2 3.4 3 0 0 3 3 3 2 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.10 EMC84937.1 - 7.3e-05 22.4 33.6 0.23 11.2 3.9 5.7 4 1 1 5 5 5 4 BED zinc finger zf-Di19 PF05605.7 EMC84937.1 - 0.00027 20.9 13.0 0.42 10.7 0.3 4.4 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMC84937.1 - 0.0027 17.7 21.6 0.19 11.8 0.1 4.6 3 2 1 4 4 4 3 C2H2 type zinc-finger (2 copies) IBR PF01485.16 EMC84937.1 - 0.0043 16.8 18.5 0.13 12.1 0.6 3.8 3 1 0 3 3 3 2 IBR domain DZR PF12773.2 EMC84937.1 - 0.12 12.1 9.1 3.9 7.3 2.1 3.3 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EMC84937.1 - 0.16 11.2 13.2 0.96 8.7 1.5 3.6 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMC84937.1 - 1 9.3 18.5 2.3 8.2 0.7 5.0 5 0 0 5 5 5 0 Zinc ribbon domain DUF629 PF04780.7 EMC84937.1 - 2.9 6.2 11.6 0.26 9.7 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF629) ATP_bind_1 PF03029.12 EMC84938.1 - 7.1e-59 199.2 0.0 2.3e-58 197.5 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EMC84938.1 - 0.00058 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EMC84938.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC84938.1 - 0.0081 15.6 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EMC84938.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_transf_49 PF13896.1 EMC84939.1 - 1.7e-52 178.4 2.2 1.8e-42 145.5 1.0 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.15 EMC84939.1 - 7.2e-21 74.6 0.4 1.7e-20 73.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_2 PF10111.4 EMC84939.1 - 0.00075 18.6 0.0 0.0026 16.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Mto2_bdg PF12808.2 EMC84939.1 - 0.15 12.1 2.6 0.13 12.3 0.4 2.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WD40_alt PF14077.1 EMC84939.1 - 1.2 8.8 7.1 0.21 11.2 2.1 1.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif Synapsin PF02078.11 EMC84940.1 - 2.6e-57 191.3 0.0 8.3e-57 189.7 0.0 1.8 2 0 0 2 2 2 1 Synapsin, N-terminal domain Synapsin_C PF02750.9 EMC84940.1 - 1.6e-21 76.3 0.5 2.4e-21 75.7 0.4 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin_N PF10581.4 EMC84940.1 - 5.2e-21 74.1 5.3 5.2e-21 74.1 3.7 2.0 2 0 0 2 2 2 1 Synapsin N-terminal TIMP PF00965.12 EMC84941.1 - 5.9e-64 215.0 10.0 7.2e-64 214.7 6.9 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 EMC84941.1 - 0.00028 20.4 1.9 0.00032 20.2 0.7 1.6 1 1 0 1 1 1 1 UNC-6/NTR/C345C module Synapsin_C PF02750.9 EMC84942.1 - 2.4e-82 274.9 1.2 2.9e-82 274.7 0.8 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain RimK PF08443.6 EMC84942.1 - 0.02 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain PI31_Prot_N PF11566.3 EMC84943.1 - 1.8e-23 82.8 0.0 3.1e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal F-box-like PF12937.2 EMC84943.1 - 1.1e-10 41.0 2.7 2.3e-10 40.0 1.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC84943.1 - 1.5e-05 24.5 1.4 3.1e-05 23.4 1.0 1.6 1 0 0 1 1 1 1 F-box domain DUF3292 PF11696.3 EMC84943.1 - 0.03 12.2 0.8 0.043 11.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) LBP_BPI_CETP_C PF02886.12 EMC84944.1 - 1.8e-40 138.7 0.2 2.9e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 EMC84944.1 - 3.9e-23 81.5 0.0 8.9e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain HLH PF00010.21 EMC84945.1 - 1.3e-17 63.2 1.8 2e-17 62.5 1.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sbi-IV PF11621.3 EMC84945.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI Muted PF14942.1 EMC84945.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein zf-H2C2_2 PF13465.1 EMC84946.1 - 5.3e-27 92.7 53.1 1.8e-07 31.1 0.6 8.5 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC84946.1 - 1e-19 69.5 64.8 8.4e-05 22.6 1.5 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC84946.1 - 8.2e-16 57.1 57.4 0.0019 18.4 0.5 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.2 EMC84946.1 - 2.4e-05 24.3 43.8 0.0014 18.7 0.6 7.5 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC84946.1 - 0.00051 19.8 17.4 0.02 14.7 0.3 5.9 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC84946.1 - 0.002 18.2 50.6 0.025 14.7 0.1 7.2 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC84946.1 - 0.0024 17.9 37.8 0.068 13.4 0.4 7.0 6 0 0 6 6 6 3 C2H2-type zinc-finger domain PyrI_C PF02748.10 EMC84946.1 - 0.01 15.2 0.4 0.01 15.2 0.3 4.5 2 1 3 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ecl1 PF12855.2 EMC84946.1 - 0.17 11.1 7.9 8.1 5.8 0.1 4.1 2 1 0 2 2 2 0 Life-span regulatory factor Mu-like_Com PF10122.4 EMC84946.1 - 0.38 9.8 12.3 2.2 7.3 4.3 3.3 2 1 0 2 2 2 0 Mu-like prophage protein Com WD40 PF00400.27 EMC84947.1 - 6.3e-19 67.0 14.5 4.6e-09 35.8 0.1 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat Ank PF00023.25 EMC84948.1 - 4.7e-27 92.4 1.1 9.4e-10 37.8 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EMC84948.1 - 1.2e-26 92.8 0.1 2.5e-13 50.1 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) BTB PF00651.26 EMC84948.1 - 2e-23 82.5 0.3 1.1e-21 76.8 0.2 3.3 2 1 1 3 3 3 1 BTB/POZ domain Ank_3 PF13606.1 EMC84948.1 - 4.2e-19 66.7 1.2 1.4e-05 24.8 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EMC84948.1 - 5.9e-18 64.8 0.0 1.9e-05 25.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC84948.1 - 7.5e-18 64.1 0.5 0.00014 22.0 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.10 EMC84948.1 - 0.00052 19.8 1.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch FAD_binding_7 PF03441.9 EMC84949.1 - 1.8e-104 348.8 0.1 2.3e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMC84949.1 - 1.6e-25 89.7 0.0 3.1e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase mTERF PF02536.9 EMC84950.1 - 1.1e-20 73.4 5.0 1.5e-20 73.1 3.4 1.1 1 0 0 1 1 1 1 mTERF DUF2795 PF11387.3 EMC84950.1 - 0.037 13.9 0.1 1.3 8.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) DUF1395 PF07160.7 EMC84950.1 - 0.043 13.3 0.2 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) XPC-binding PF09280.6 EMC84950.1 - 0.075 12.5 1.9 1.9 8.0 0.0 3.5 3 1 1 4 4 4 0 XPC-binding domain RRF_GI PF12614.3 EMC84950.1 - 0.08 12.7 0.9 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 Ribosome recycling factor UPF0444 PF15475.1 EMC84951.1 - 1.1e-45 153.6 13.5 1.3e-45 153.3 9.4 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 SseC PF04888.7 EMC84951.1 - 0.38 10.0 4.8 0.44 9.8 3.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ric8 PF10165.4 EMC84952.1 - 3.7e-140 467.7 3.2 4.6e-140 467.3 2.2 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn RFX_DNA_binding PF02257.10 EMC84953.1 - 1e-34 118.4 0.0 4.5e-34 116.4 0.0 2.2 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 EMC84953.1 - 8.9e-05 22.6 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like RNA_pol_Rpb2_6 PF00562.23 EMC84954.1 - 2.6e-125 418.1 0.0 1.6e-124 415.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMC84954.1 - 2.8e-54 183.1 1.7 4e-54 182.6 0.7 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EMC84954.1 - 9.6e-32 109.0 0.2 3.7e-31 107.2 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EMC84954.1 - 5.9e-28 97.5 1.6 6.7e-28 97.3 0.4 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EMC84954.1 - 6.1e-23 80.3 1.0 8.2e-22 76.7 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EMC84954.1 - 1.7e-22 78.9 0.5 4.6e-22 77.5 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EMC84954.1 - 4.9e-13 48.8 2.2 4.9e-13 48.8 1.5 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 5 Filament PF00038.16 EMC84956.1 - 1.2e-06 28.1 33.1 0.00014 21.5 12.6 3.2 1 1 1 2 2 2 2 Intermediate filament protein AAA_13 PF13166.1 EMC84956.1 - 4.3e-06 25.5 37.3 0.011 14.2 14.5 3.0 1 1 2 3 3 3 3 AAA domain Tropomyosin_1 PF12718.2 EMC84956.1 - 3.1e-05 23.8 12.4 3.1e-05 23.8 8.6 5.1 2 2 1 5 5 5 2 Tropomyosin like Reo_sigmaC PF04582.7 EMC84956.1 - 6.2e-05 22.3 32.9 0.0088 15.2 8.0 4.5 1 1 3 4 4 4 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EMC84956.1 - 7.7e-05 22.5 31.2 0.042 13.6 2.2 5.1 1 1 4 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 EMC84956.1 - 0.00012 20.7 42.4 0.03 12.7 19.6 2.6 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Fib_alpha PF08702.5 EMC84956.1 - 0.00037 20.6 39.7 0.16 12.0 0.3 5.0 1 1 2 5 5 5 3 Fibrinogen alpha/beta chain family Tropomyosin PF00261.15 EMC84956.1 - 0.00075 18.6 42.8 0.0046 16.0 2.7 5.8 1 1 2 4 4 4 2 Tropomyosin IncA PF04156.9 EMC84956.1 - 0.00098 18.7 45.7 0.016 14.8 0.9 4.7 1 1 3 4 4 4 2 IncA protein EzrA PF06160.7 EMC84956.1 - 0.0012 17.0 36.3 0.17 10.0 12.1 3.8 1 1 2 3 3 3 3 Septation ring formation regulator, EzrA Bacillus_HBL PF05791.6 EMC84956.1 - 0.0022 17.4 32.7 0.022 14.1 0.6 5.1 1 1 4 6 6 6 3 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.4 EMC84956.1 - 0.011 15.8 0.3 0.011 15.8 0.2 6.9 2 2 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 EMC84956.1 - 0.019 14.1 43.0 0.01 15.0 7.9 4.4 1 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Hemerythrin PF01814.18 EMC84956.1 - 0.029 14.5 6.9 4.6 7.4 1.6 3.7 2 2 0 3 3 3 0 Hemerythrin HHE cation binding domain Syntaxin-6_N PF09177.6 EMC84956.1 - 0.038 14.3 34.7 0.75 10.2 3.0 5.9 2 1 4 6 6 6 0 Syntaxin 6, N-terminal COG2 PF06148.6 EMC84956.1 - 0.038 13.8 0.8 0.038 13.8 0.5 6.2 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Cob_adeno_trans PF01923.13 EMC84956.1 - 0.043 13.6 17.2 1.8 8.2 0.3 4.8 1 1 3 5 5 5 0 Cobalamin adenosyltransferase DUF4200 PF13863.1 EMC84956.1 - 0.12 12.2 39.3 1.5 8.7 2.8 5.9 2 1 3 5 5 5 0 Domain of unknown function (DUF4200) DUF3584 PF12128.3 EMC84956.1 - 0.13 9.5 35.9 0.022 12.1 14.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 EMC84956.1 - 0.2 9.8 43.8 0.23 9.6 1.6 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 EMC84956.1 - 0.3 10.9 49.3 0.12 12.2 0.5 5.4 2 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4172 PF13776.1 EMC84956.1 - 0.52 10.4 7.8 0.28 11.2 0.6 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4172) DUF1664 PF07889.7 EMC84956.1 - 0.53 10.0 40.3 0.74 9.6 0.6 7.1 1 1 8 9 9 9 0 Protein of unknown function (DUF1664) Fez1 PF06818.10 EMC84956.1 - 1.4 8.8 34.0 1.8 8.5 0.4 3.9 1 1 2 3 3 3 0 Fez1 APG6 PF04111.7 EMC84956.1 - 1.5 7.7 40.3 0.019 14.0 7.6 4.0 1 1 4 5 5 5 0 Autophagy protein Apg6 Laminin_I PF06008.9 EMC84956.1 - 1.9 7.7 36.9 0.15 11.3 4.1 4.6 1 1 1 3 3 3 0 Laminin Domain I Atg14 PF10186.4 EMC84956.1 - 6.2 5.6 32.5 0.63 8.9 0.3 4.2 1 1 2 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 PEP-utilisers_N PF05524.8 EMC84956.1 - 7.4 6.4 18.3 62 3.4 1.4 5.4 2 2 2 4 4 4 0 PEP-utilising enzyme, N-terminal DUF2524 PF10732.4 EMC84956.1 - 7.5 6.7 18.9 30 4.8 0.6 5.7 5 1 0 5 5 5 0 Protein of unknown function (DUF2524) FlaC_arch PF05377.6 EMC84956.1 - 8.4 6.3 46.2 0.53 10.2 2.4 8.8 7 2 1 9 9 9 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EMC84956.1 - 9.1 6.0 42.1 1 9.1 5.8 4.8 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Pkinase_Tyr PF07714.12 EMC84957.1 - 1.7e-37 128.8 0.1 3.3e-37 127.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase SAM_1 PF00536.25 EMC84957.1 - 1.2e-24 86.1 0.0 1.8e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC84957.1 - 4.6e-22 77.6 0.0 7.3e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EMC84957.1 - 1.5e-11 43.9 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4083 PF13314.1 EMC84959.1 - 0.11 12.3 0.6 14 5.6 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) CarbpepA_inh PF02977.10 EMC84961.1 - 0.0052 16.3 0.0 0.016 14.7 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase A inhibitor DUF4210 PF13915.1 EMC84962.1 - 8.8e-22 77.1 0.1 2.3e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EMC84962.1 - 3.6e-17 61.9 0.3 1.1e-16 60.4 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation during meiosis Band_7 PF01145.20 EMC84963.1 - 6.8e-28 97.7 0.1 6.8e-28 97.7 0.0 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMC84963.1 - 0.037 13.5 0.0 0.08 12.4 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family TPR_11 PF13414.1 EMC84964.1 - 3e-21 74.8 3.1 7.5e-08 31.9 0.2 3.9 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EMC84964.1 - 3e-15 54.8 5.4 0.03 14.2 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC84964.1 - 2.3e-12 45.9 2.0 0.0012 18.3 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC84964.1 - 6.8e-12 45.7 17.9 0.00012 22.6 0.3 5.8 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMC84964.1 - 2.5e-09 36.9 9.2 0.00049 19.9 0.1 6.1 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC84964.1 - 2.7e-09 37.2 11.9 0.00039 20.7 0.1 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC84964.1 - 2.8e-07 30.5 2.3 1 9.5 0.0 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EMC84964.1 - 6.2e-05 23.2 21.3 0.6 10.8 0.1 7.8 5 3 2 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC84964.1 - 0.00016 21.2 0.0 4.6 7.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.12 EMC84964.1 - 0.00087 19.6 0.0 0.00087 19.6 0.0 4.5 4 2 1 5 5 4 1 Bacterial transcriptional activator domain TPR_7 PF13176.1 EMC84964.1 - 0.0023 17.6 8.0 2.8 7.9 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC84964.1 - 0.015 15.6 5.9 40 4.9 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Cohesin_load PF10345.4 EMC84964.1 - 0.055 11.6 0.1 0.12 10.5 0.1 1.5 1 0 0 1 1 1 0 Cohesin loading factor TPR_17 PF13431.1 EMC84964.1 - 0.082 13.1 0.2 15 6.0 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 EMC84964.1 - 0.17 11.6 0.7 33 4.3 0.0 3.7 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_20 PF14561.1 EMC84964.1 - 9.2 6.4 12.6 3.2 7.9 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA PF00004.24 EMC84965.1 - 6.8e-97 320.7 0.0 4e-47 159.7 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMC84965.1 - 5.2e-24 84.0 0.4 7.8e-23 80.2 0.4 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.1 EMC84965.1 - 1.5e-14 54.4 0.6 9.1e-07 29.0 0.3 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EMC84965.1 - 2.1e-13 51.1 0.1 2.7e-05 24.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EMC84965.1 - 2.6e-13 49.5 0.0 1.8e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC84965.1 - 2.7e-12 46.9 1.2 0.00023 21.2 0.1 4.6 3 2 1 4 4 3 2 AAA domain CDC48_2 PF02933.12 EMC84965.1 - 8.7e-12 44.5 0.0 1.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.1 EMC84965.1 - 8.7e-12 45.1 0.0 2e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMC84965.1 - 8e-11 41.8 0.2 4.2e-05 23.3 0.0 3.7 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMC84965.1 - 1.5e-10 41.2 0.0 3.5e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EMC84965.1 - 7.2e-09 34.8 0.1 0.00085 18.1 0.0 2.6 3 0 0 3 3 2 2 TIP49 C-terminus AAA_14 PF13173.1 EMC84965.1 - 8.2e-09 35.4 0.0 0.0038 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EMC84965.1 - 2.2e-08 33.7 0.1 0.009 15.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 EMC84965.1 - 2.7e-08 33.4 3.0 0.022 14.1 0.0 4.1 2 2 1 4 4 4 3 AAA domain Zeta_toxin PF06414.7 EMC84965.1 - 3.4e-08 32.8 0.0 0.0045 16.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EMC84965.1 - 9.8e-08 32.3 0.0 0.014 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EMC84965.1 - 1.1e-07 31.8 0.1 0.27 10.8 0.0 4.0 2 2 1 3 3 3 2 Archaeal ATPase Vps4_C PF09336.5 EMC84965.1 - 1.2e-07 31.4 0.6 6.6e-05 22.7 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 EMC84965.1 - 1.5e-07 31.5 0.0 0.0055 16.8 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_19 PF13245.1 EMC84965.1 - 2.7e-07 30.2 1.8 0.0071 16.0 0.3 2.7 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EMC84965.1 - 3.2e-07 29.7 0.1 0.017 14.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMC84965.1 - 1.2e-06 28.6 0.4 0.072 13.0 0.0 3.1 4 0 0 4 4 2 2 AAA domain Parvo_NS1 PF01057.12 EMC84965.1 - 2.8e-06 26.4 0.1 0.029 13.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 KaiC PF06745.8 EMC84965.1 - 4.5e-06 25.9 0.3 0.39 9.7 0.0 3.4 2 1 1 3 3 3 2 KaiC NACHT PF05729.7 EMC84965.1 - 4.7e-06 26.3 0.1 0.14 11.7 0.0 4.1 3 1 1 4 4 4 1 NACHT domain Sigma54_activ_2 PF14532.1 EMC84965.1 - 6.5e-06 26.2 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EMC84965.1 - 6.8e-06 26.4 0.1 0.0085 16.3 0.0 3.6 3 1 0 3 3 2 1 ABC transporter DUF815 PF05673.8 EMC84965.1 - 7.6e-06 25.0 0.0 0.0093 14.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 EMC84965.1 - 9.9e-06 25.3 0.0 0.1 12.2 0.0 3.0 3 0 0 3 3 2 2 Bacterial dnaA protein ResIII PF04851.10 EMC84965.1 - 2.8e-05 24.0 0.0 0.0065 16.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EMC84965.1 - 3.8e-05 23.3 0.0 0.27 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EMC84965.1 - 4.8e-05 23.0 0.0 0.0015 18.0 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EMC84965.1 - 7.5e-05 21.7 0.0 0.087 11.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 EMC84965.1 - 8.6e-05 22.0 0.0 0.37 10.2 0.0 3.0 2 2 0 2 2 2 2 Sigma-54 interaction domain DUF2075 PF09848.4 EMC84965.1 - 0.0004 19.4 0.1 0.32 9.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EMC84965.1 - 0.00046 19.4 0.6 0.95 8.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EMC84965.1 - 0.00048 19.7 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EMC84965.1 - 0.0029 17.2 0.0 0.88 9.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 EMC84965.1 - 0.0052 16.6 1.5 1.3 8.8 0.0 3.2 3 0 0 3 3 2 1 Shikimate kinase NTPase_1 PF03266.10 EMC84965.1 - 0.007 16.0 0.2 1.4 8.5 0.0 3.3 3 0 0 3 3 3 1 NTPase T2SE PF00437.15 EMC84965.1 - 0.0087 14.9 0.0 2.3 7.0 0.0 3.1 3 1 0 4 4 3 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EMC84965.1 - 0.0097 15.4 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EMC84965.1 - 0.011 16.1 0.0 4.2 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMC84965.1 - 0.014 14.9 0.1 4 7.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Cytidylate_kin2 PF13189.1 EMC84965.1 - 0.015 15.2 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_30 PF13604.1 EMC84965.1 - 0.018 14.6 0.0 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMC84965.1 - 0.025 14.0 0.4 2.4 7.5 0.0 3.8 5 0 0 5 5 4 0 AAA-like domain DNA_ligase_A_C PF04679.10 EMC84965.1 - 0.076 13.4 0.1 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region KAP_NTPase PF07693.9 EMC84965.1 - 0.081 11.9 0.0 5.1 5.9 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 EMC84965.1 - 0.15 11.5 0.2 15 5.0 0.1 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_21 PF13304.1 EMC84965.1 - 0.29 11.0 0.5 24 4.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain DnaJ PF00226.26 EMC84966.1 - 8e-30 102.3 4.6 1.3e-29 101.7 3.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMC84966.1 - 1.2e-24 85.9 0.8 2.4e-22 78.6 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain EF-hand_6 PF13405.1 EMC84967.1 - 5.8e-07 28.8 0.1 0.0052 16.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EMC84967.1 - 3.3e-06 27.1 0.0 0.018 15.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC84967.1 - 1e-05 24.4 0.4 0.065 12.5 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EMC84967.1 - 0.004 16.4 0.4 0.3 10.5 0.3 2.5 2 0 0 2 2 2 1 EF hand PHD PF00628.24 EMC84967.1 - 0.017 14.8 7.3 0.066 12.9 5.1 2.0 1 1 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EMC84967.1 - 0.017 14.8 0.5 0.017 14.8 0.3 2.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_8 PF13833.1 EMC84967.1 - 0.043 13.4 0.4 3.4 7.3 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair DUF1360 PF07098.6 EMC84967.1 - 0.098 12.3 1.5 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Prok-RING_1 PF14446.1 EMC84967.1 - 0.1 12.3 2.8 0.12 12.1 0.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 EMC84967.1 - 0.18 11.9 3.0 0.51 10.5 2.0 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain RecR PF02132.10 EMC84967.1 - 0.35 10.3 2.4 3.1 7.2 0.9 2.5 2 0 0 2 2 2 0 RecR protein zf-RING_2 PF13639.1 EMC84967.1 - 0.49 10.2 5.2 1.3 8.8 3.6 1.8 1 0 0 1 1 1 0 Ring finger domain IL8 PF00048.15 EMC84968.1 - 2.5e-18 65.7 0.1 3.4e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 EMC84969.1 - 1.8e-18 66.2 0.2 2.2e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like fn3 PF00041.16 EMC84970.1 - 1.1e-07 31.8 1.6 2.6e-07 30.6 0.1 2.4 2 1 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.1 EMC84970.1 - 2.1e-06 27.7 1.6 1.1e-05 25.4 0.1 2.5 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.11 EMC84970.1 - 0.0077 16.0 0.3 0.15 11.9 0.1 2.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 EMC84970.1 - 0.0078 16.3 0.1 0.0078 16.3 0.1 2.5 2 1 0 2 2 2 1 Immunoglobulin domain PKD PF00801.15 EMC84970.1 - 0.057 13.1 0.4 0.27 10.9 0.0 2.4 3 0 0 3 3 3 0 PKD domain Ig_3 PF13927.1 EMC84970.1 - 0.36 11.3 5.1 1.4 9.4 0.0 3.5 3 1 0 3 3 3 0 Immunoglobulin domain ERG2_Sigma1R PF04622.7 EMC84974.1 - 7.6e-70 234.5 1.3 9.5e-70 234.2 0.9 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ARID PF01388.16 EMC84975.1 - 1.6e-28 98.4 0.0 2.7e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ketoacyl-synt PF00109.21 EMC84975.1 - 0.018 14.5 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF3416 PF11896.3 EMC84975.1 - 0.14 12.0 0.9 0.22 11.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Dynactin_p22 PF07426.6 EMC84976.1 - 1.3e-60 203.6 6.9 1.4e-60 203.5 4.8 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 BCDHK_Adom3 PF10436.4 EMC84976.1 - 0.043 13.3 1.4 0.062 12.8 0.8 1.3 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF2661 PF10860.3 EMC84976.1 - 0.048 13.8 0.4 0.31 11.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2661) Alba PF01918.16 EMC84978.1 - 5.7e-15 54.6 1.3 8.2e-15 54.1 0.9 1.3 1 0 0 1 1 1 1 Alba WD40 PF00400.27 EMC84980.1 - 1.3e-18 66.1 6.4 4.4e-08 32.6 1.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat FAM219A PF15260.1 EMC84981.1 - 1.7e-57 193.1 3.2 2.2e-57 192.7 2.2 1.1 1 0 0 1 1 1 1 Protein family FAM219A KGG PF10685.4 EMC84981.1 - 0.15 12.0 0.5 0.26 11.2 0.4 1.4 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif SMRP1 PF15181.1 EMC84982.1 - 5.6e-100 334.0 5.6 6.2e-100 333.8 3.9 1.0 1 0 0 1 1 1 1 Spermatid-specific manchette-related protein 1 Glyco_hydro_31 PF01055.21 EMC84983.1 - 7.7e-66 222.7 1.4 2.6e-63 214.4 1.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 EMC84983.1 - 0.00033 19.4 0.2 0.00086 18.0 0.2 1.6 1 1 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 EMC84984.1 - 6.2e-65 219.7 2.5 2e-62 211.4 1.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 EMC84984.1 - 0.00086 18.1 0.3 0.0022 16.7 0.2 1.6 1 1 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 EMC84985.1 - 3.2e-12 46.5 8.2 2.9e-10 40.2 1.9 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 EMC84985.1 - 2.2e-05 23.8 0.1 4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family RicinB_lectin_2 PF14200.1 EMC84985.1 - 0.00037 20.8 0.5 0.0032 17.8 0.0 2.4 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like NUDIX PF00293.23 EMC84987.1 - 6.5e-20 71.1 0.1 7.2e-20 71.0 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain Kinesin PF00225.18 EMC84988.1 - 2.2e-52 177.8 1.7 4.5e-52 176.8 1.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 EMC84988.1 - 0.0039 17.3 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC84988.1 - 0.034 13.9 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) UBA PF00627.26 EMC84989.1 - 2.6e-09 36.6 0.1 5.1e-05 22.9 0.0 4.0 3 0 0 3 3 3 2 UBA/TS-N domain UBA_3 PF09288.5 EMC84989.1 - 0.0049 16.4 1.4 0.42 10.2 0.0 3.1 3 0 0 3 3 3 1 Fungal ubiquitin-associated domain RNase_T PF00929.19 EMC84989.1 - 0.12 12.6 0.1 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Exonuclease DUF3697 PF12478.3 EMC84990.1 - 4.8e-20 70.8 0.6 9.4e-20 69.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 UBA_4 PF14555.1 EMC84990.1 - 1.5e-05 24.4 0.0 3.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EMC84990.1 - 1.6e-05 24.5 0.1 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 EMC84990.1 - 0.072 12.6 1.8 0.1 12.0 0.1 2.2 2 0 0 2 2 2 0 CUE domain DUF1296 PF06972.6 EMC84990.1 - 0.096 12.6 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) zf-RING_2 PF13639.1 EMC84991.1 - 6.1e-15 54.7 9.1 6.1e-15 54.7 6.3 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMC84991.1 - 3.7e-08 33.3 8.9 3.7e-08 33.3 6.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC84991.1 - 2.3e-07 30.3 7.7 2.3e-07 30.3 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84991.1 - 2.1e-06 27.6 7.3 2.1e-06 27.6 5.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84991.1 - 1.1e-05 25.0 6.5 4.1e-05 23.2 4.5 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC84991.1 - 0.00056 19.5 4.2 0.00056 19.5 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMC84991.1 - 0.044 13.7 4.2 0.15 12.0 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 EMC84991.1 - 0.077 12.8 7.3 0.43 10.4 5.1 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EMC84991.1 - 0.93 9.2 12.5 1.2 8.8 4.7 2.7 2 0 0 2 2 2 0 PHD-finger Spt4 PF06093.8 EMC84992.1 - 9.8e-10 38.1 0.1 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger SH3_9 PF14604.1 EMC84993.1 - 5.1e-12 45.1 0.1 9.8e-12 44.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain fn3 PF00041.16 EMC84993.1 - 3.6e-10 39.8 2.3 0.0024 17.9 0.0 4.3 3 1 0 3 3 3 2 Fibronectin type III domain SH3_2 PF07653.12 EMC84993.1 - 2.1e-09 36.7 0.0 4.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC84993.1 - 0.0035 16.7 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain An_peroxidase PF03098.10 EMC84994.1 - 1.5e-167 558.1 0.0 1.9e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF3161 PF11362.3 EMC84994.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Acyltransferase PF01553.16 EMC84995.1 - 8.2e-35 119.1 0.1 1.2e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase An_peroxidase PF03098.10 EMC84996.1 - 3e-177 590.2 0.0 3.5e-177 589.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase IL8 PF00048.15 EMC84997.1 - 1.3e-23 82.6 0.3 1.8e-23 82.2 0.2 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Neuroparsin PF07327.6 EMC84997.1 - 0.1 12.8 0.5 0.29 11.3 0.2 1.8 1 1 1 2 2 2 0 Neuroparsin SPRY PF00622.23 EMC84998.1 - 1.2e-25 89.9 0.0 2.1e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 EMC84998.1 - 1.4e-17 62.9 0.8 3.5e-17 61.6 0.1 2.0 2 0 0 2 2 2 1 SPRY-associated domain zf-C3HC4_4 PF15227.1 EMC84998.1 - 3.7e-13 49.1 11.2 3.7e-13 49.1 7.8 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMC84998.1 - 3.6e-09 36.3 13.2 1.2e-08 34.6 6.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.19 EMC84998.1 - 5.2e-09 35.8 2.8 5.2e-09 35.8 1.9 3.5 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4 PF00097.20 EMC84998.1 - 6.7e-09 35.2 9.5 6.7e-09 35.2 6.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC84998.1 - 4.5e-08 32.9 11.0 4.5e-08 32.9 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC84998.1 - 8.4e-08 31.8 5.0 8.4e-08 31.8 3.5 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EMC84998.1 - 0.00068 19.2 11.7 0.00068 19.2 8.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC84998.1 - 0.0013 18.3 8.1 0.0013 18.3 5.6 2.7 2 1 0 2 2 2 1 zinc-RING finger domain U-box PF04564.10 EMC84998.1 - 0.0043 16.9 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-Nse PF11789.3 EMC84998.1 - 0.012 15.1 3.1 0.03 13.8 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Hemopexin PF00045.14 EMC84998.1 - 0.037 13.7 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Hemopexin zf-RING_6 PF14835.1 EMC84998.1 - 0.078 12.7 5.5 0.22 11.3 3.8 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EMC84998.1 - 1.8 8.7 12.2 6.9 6.8 4.6 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger IncA PF04156.9 EMC84998.1 - 2.2 7.8 12.3 3.8 7.0 8.5 1.3 1 0 0 1 1 1 0 IncA protein zf-Di19 PF05605.7 EMC84998.1 - 3.4 7.8 10.3 20 5.3 0.0 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding IL8 PF00048.15 EMC84999.1 - 1.2e-16 60.4 0.2 1.7e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DUF1450 PF07293.6 EMC84999.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) Nol1_Nop2_Fmu PF01189.12 EMC85000.1 - 3.9e-34 118.3 0.0 4.7e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EMC85000.1 - 0.00092 19.2 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMC85000.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EMC85000.1 - 0.0026 17.3 0.0 0.0069 15.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC85000.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Fibrillarin PF01269.12 EMC85000.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin SPRY PF00622.23 EMC85001.1 - 7.9e-23 80.8 0.0 1.3e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_4 PF15227.1 EMC85001.1 - 1.3e-12 47.3 9.5 1.3e-12 47.3 6.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMC85001.1 - 1.9e-10 40.1 6.0 7e-10 38.4 4.2 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC85001.1 - 1.9e-09 37.3 8.5 1.9e-09 37.3 5.9 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 EMC85001.1 - 4.1e-09 36.1 1.2 4.1e-09 36.1 0.9 4.2 4 0 0 4 4 4 1 B-box zinc finger PRY PF13765.1 EMC85001.1 - 1.3e-08 34.2 0.1 3e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 SPRY-associated domain zf-C3HC4_3 PF13920.1 EMC85001.1 - 1.6e-08 34.0 8.2 1.6e-08 34.0 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC85001.1 - 1.7e-08 33.9 3.2 1.7e-08 33.9 2.2 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC85001.1 - 3.6e-07 29.8 6.0 3.6e-07 29.8 4.2 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC85001.1 - 4.3e-07 29.6 7.8 4.3e-07 29.6 5.4 2.3 3 0 0 3 3 2 1 Ring finger domain zf-Nse PF11789.3 EMC85001.1 - 0.0052 16.2 2.7 0.0052 16.2 1.9 2.4 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EMC85001.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.1 EMC85001.1 - 0.026 14.0 4.1 0.18 11.4 3.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prominin PF05478.6 EMC85001.1 - 0.055 11.0 1.4 0.078 10.5 1.0 1.1 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.13 EMC85001.1 - 0.074 12.5 1.6 0.14 11.6 1.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Bacillus_HBL PF05791.6 EMC85001.1 - 0.9 8.8 5.2 9.3 5.5 0.4 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) zf-RING_6 PF14835.1 EMC85001.1 - 1.4 8.7 12.5 0.32 10.8 4.8 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EMC85001.1 - 2.2 8.1 7.7 0.24 11.2 1.8 2.0 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EMC85001.1 - 4.8 7.0 13.2 2.1 8.2 3.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon Baculo_IE-1 PF05290.6 EMC85001.1 - 8.7 6.0 8.2 0.43 10.2 1.2 2.1 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) FKBP_C PF00254.23 EMC85002.1 - 1.5e-14 53.7 0.0 3.2e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.12 EMC85002.1 - 7.7e-07 28.5 6.7 0.00091 18.9 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC85002.1 - 9.2e-07 28.4 2.0 2.5e-06 27.0 0.2 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EMC85002.1 - 1.8e-06 27.7 2.0 2.9e-05 23.9 0.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC85002.1 - 0.0019 18.2 4.1 0.015 15.3 2.8 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EMC85002.1 - 0.0088 16.7 4.2 1.4 9.6 0.8 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC85002.1 - 0.013 15.0 4.6 0.097 12.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC85002.1 - 0.014 15.0 3.6 0.015 15.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC85002.1 - 0.061 13.2 0.3 0.061 13.2 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC85002.1 - 0.063 13.1 2.0 0.22 11.4 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EMC85002.1 - 0.081 13.6 0.6 2.6 8.9 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Couple_hipA PF13657.1 EMC85002.1 - 0.085 13.1 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 HipA N-terminal domain TPR_7 PF13176.1 EMC85002.1 - 0.14 12.0 0.9 9.7 6.2 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Bromodomain PF00439.20 EMC85004.1 - 1.2e-22 79.5 0.1 2.8e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 EMC85004.1 - 5e-13 48.5 5.9 5e-13 48.5 4.1 2.1 2 0 0 2 2 2 1 PHD-finger WHIM2 PF15613.1 EMC85004.1 - 2.1e-08 33.7 0.3 4.5e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EMC85004.1 - 4.1e-06 26.4 0.1 1.6e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Prok-RING_1 PF14446.1 EMC85004.1 - 0.00052 19.6 1.4 0.00052 19.6 1.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EMC85004.1 - 0.0036 16.5 0.5 0.0089 15.3 0.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 EMC85004.1 - 0.004 16.9 5.2 0.011 15.5 3.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC85004.1 - 0.014 15.4 4.4 0.047 13.7 3.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger zf-HC5HC2H PF13771.1 EMC85004.1 - 0.016 15.3 3.2 0.067 13.3 2.3 2.1 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-Apc11 PF12861.2 EMC85004.1 - 0.019 14.7 1.7 0.048 13.4 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger WAC_Acf1_DNA_bd PF10537.4 EMC85005.1 - 5.2e-07 29.7 0.0 8.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal Fibrinogen_C PF00147.13 EMC85007.1 - 4.6e-81 271.8 6.9 6.1e-41 140.5 0.7 2.0 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Ephrin_lbd PF01404.14 EMC85007.1 - 0.025 14.3 6.1 0.61 9.8 0.3 2.3 2 0 0 2 2 2 0 Ephrin receptor ligand binding domain Imm37 PF15598.1 EMC85007.1 - 0.7 9.7 3.1 21 4.9 0.0 3.6 2 2 2 4 4 4 0 Immunity protein 37 PT PF04886.7 EMC85008.1 - 6.6e-12 44.5 0.0 0.0045 16.2 0.0 4.2 1 1 0 1 1 1 1 PT repeat WD40 PF00400.27 EMC85009.1 - 3.9e-20 70.9 3.9 3.9e-08 32.8 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EMC85009.1 - 0.02 14.5 0.0 0.22 11.2 0.0 2.5 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF1797 PF08796.5 EMC85009.1 - 0.085 12.7 0.4 7.3 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) B9-C2 PF07162.6 EMC85011.1 - 3.2e-43 147.4 0.0 3.9e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Syntaxin PF00804.20 EMC85013.1 - 2.4e-33 114.3 3.4 2.4e-16 59.7 0.0 3.5 3 1 0 3 3 3 2 Syntaxin SNARE PF05739.14 EMC85013.1 - 3.7e-25 87.3 4.0 1.3e-24 85.5 1.1 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EMC85013.1 - 0.0032 17.4 4.5 0.028 14.4 0.1 3.2 3 1 0 3 3 3 1 Syntaxin-like protein GNVR PF13807.1 EMC85013.1 - 0.0062 16.2 0.1 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Lzipper-MIP1 PF14389.1 EMC85013.1 - 0.067 13.3 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Synaptobrevin PF00957.16 EMC85013.1 - 0.28 10.8 2.2 0.65 9.6 0.4 2.4 2 0 0 2 2 2 0 Synaptobrevin WBS_methylT PF12589.3 EMC85014.1 - 1.6e-18 66.9 13.2 8.3e-18 64.6 9.1 2.0 1 1 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EMC85014.1 - 5.1e-11 42.9 0.0 8.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC85014.1 - 2e-06 28.0 0.0 3.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC85014.1 - 1.1e-05 25.9 0.0 1.8e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC85014.1 - 0.00019 21.2 0.0 0.00033 20.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC85014.1 - 0.00027 21.3 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC85014.1 - 0.00029 20.4 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC85014.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Mod_r PF07200.8 EMC85015.1 - 2.9e-14 53.2 0.2 3.2e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_S PF02609.11 EMC85015.1 - 0.09 12.5 0.8 0.16 11.7 0.2 1.7 1 1 1 2 2 2 0 Exonuclease VII small subunit Mod_r PF07200.8 EMC85016.1 - 2.6e-13 50.1 0.4 2.7e-13 50.0 0.3 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Fibrinogen_C PF00147.13 EMC85017.1 - 8.5e-54 182.6 4.6 9.3e-54 182.5 3.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.13 EMC85018.1 - 3.1e-52 177.5 2.7 3.4e-52 177.3 1.9 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain TLV_coat PF00429.14 EMC85019.1 - 1.5e-10 40.2 0.4 1.7e-10 40.0 0.3 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC85019.1 - 0.0065 16.0 1.8 0.0088 15.6 0.1 1.8 1 1 1 2 2 2 1 Retroviral envelope protein PLAC8 PF04749.12 EMC85020.1 - 2e-11 44.3 14.0 6.6e-11 42.7 9.7 1.7 1 1 0 1 1 1 1 PLAC8 family zf-CXXC PF02008.15 EMC85020.1 - 2.5 7.9 15.8 3.3 7.6 4.3 2.3 1 1 1 2 2 2 0 CXXC zinc finger domain PLAC8 PF04749.12 EMC85021.1 - 3.1e-17 63.0 14.3 1.3e-16 61.0 9.9 1.8 1 1 0 1 1 1 1 PLAC8 family ABC2_membrane PF01061.19 EMC85022.1 - 2.4e-38 131.3 24.2 2.4e-38 131.3 16.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EMC85022.1 - 6.5e-22 78.2 0.0 1.1e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMC85022.1 - 7.1e-09 36.0 0.1 1.2e-06 28.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMC85022.1 - 4.1e-07 29.3 18.4 6.5e-07 28.7 12.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.14 EMC85022.1 - 7e-06 25.4 0.1 0.00016 20.9 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMC85022.1 - 8.9e-05 22.9 0.4 0.00026 21.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EMC85022.1 - 0.00021 20.5 0.2 2.1 7.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EMC85022.1 - 0.0043 16.2 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMC85022.1 - 0.0067 15.9 0.1 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Adeno_IVa2 PF02456.10 EMC85022.1 - 0.0086 14.7 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_16 PF13191.1 EMC85022.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PDR_assoc PF08370.6 EMC85022.1 - 0.012 15.0 0.1 0.048 13.1 0.1 2.1 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_17 PF13207.1 EMC85022.1 - 0.02 15.6 0.0 0.12 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMC85022.1 - 0.064 13.5 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMC85022.1 - 0.098 12.7 0.1 0.42 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMC85022.1 - 0.18 11.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EMC85022.1 - 0.43 10.3 3.5 0.45 10.2 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF87 PKD_channel PF08016.7 EMC85023.1 - 1.7e-147 491.2 24.7 1.7e-147 491.2 17.1 2.3 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 EMC85023.1 - 4.4e-22 78.3 29.1 4.4e-22 78.3 20.1 1.9 2 0 0 2 2 2 1 Ion transport protein EF-hand_1 PF00036.27 EMC85023.1 - 5.8e-05 22.1 1.3 0.055 12.7 0.2 3.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EMC85023.1 - 0.00083 18.9 1.6 0.032 13.8 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC85023.1 - 0.0042 16.8 2.1 0.1 12.5 0.1 3.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 EMC85023.1 - 0.026 14.6 1.4 0.082 13.0 0.4 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF445 PF04286.7 EMC85023.1 - 0.28 10.6 7.6 2.4 7.5 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Osteopontin PF00865.13 EMC85024.1 - 2.2e-29 102.6 35.7 3.6e-15 55.9 8.8 2.8 1 1 1 2 2 2 2 Osteopontin BSP_II PF05432.6 EMC85026.1 - 5.8e-62 209.6 61.3 1.8e-61 207.9 42.5 1.8 1 1 0 1 1 1 1 Bone sialoprotein II (BSP-II) Retinal PF15449.1 EMC85026.1 - 0.012 13.3 8.2 0.018 12.7 5.7 1.2 1 0 0 1 1 1 0 Retinal protein Sex_peptide PF08138.6 EMC85026.1 - 0.19 11.5 0.2 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Sex peptide (SP) family Pilt PF15453.1 EMC85026.1 - 0.59 9.7 13.0 1 8.9 9.0 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF4045 PF13254.1 EMC85026.1 - 0.9 8.7 9.5 1.4 8.1 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 EMC85026.1 - 1.9 6.1 7.1 2.3 5.8 4.9 1.2 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 EMC85026.1 - 2.8 5.5 7.4 3.4 5.2 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPARC_Ca_bdg PF10591.4 EMC85027.1 - 2.9e-42 143.2 1.7 2.9e-42 143.2 1.2 3.3 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.16 EMC85027.1 - 1.5e-11 44.1 6.6 4.2e-11 42.6 4.6 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EMC85027.1 - 6.1e-10 38.8 3.3 1.9e-09 37.2 2.3 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 EMC85027.1 - 4.6e-09 35.9 7.9 1.4e-08 34.4 5.5 1.9 1 0 0 1 1 1 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.27 EMC85027.1 - 0.056 12.7 0.2 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 EF hand NUDIX PF00293.23 EMC85028.1 - 2e-08 33.9 0.1 6.1e-08 32.3 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain adh_short PF00106.20 EMC85029.1 - 5.8e-31 107.6 0.7 8.3e-31 107.1 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC85029.1 - 7.8e-12 45.2 0.5 1.4e-11 44.3 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC85029.1 - 5.3e-08 32.9 0.0 7.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.1 EMC85029.1 - 0.029 14.7 0.0 0.078 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ureidogly_hydro PF04115.7 EMC85029.1 - 0.035 13.4 0.1 0.059 12.7 0.0 1.4 1 1 0 1 1 1 0 Ureidoglycolate hydrolase Ldh_1_N PF00056.18 EMC85029.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMC85029.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMC85029.1 - 0.076 12.6 0.3 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EMC85030.1 - 1.7e-30 106.1 0.5 2.5e-30 105.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC85030.1 - 1.7e-11 44.1 0.4 2.7e-11 43.4 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC85030.1 - 2.9e-08 33.8 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.1 EMC85030.1 - 0.032 14.6 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.18 EMC85030.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMC85030.1 - 0.067 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ureidogly_hydro PF04115.7 EMC85030.1 - 0.089 12.1 0.1 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Ureidoglycolate hydrolase 3HCDH_N PF02737.13 EMC85030.1 - 0.09 12.4 0.5 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rop PF01815.11 EMC85030.1 - 0.12 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Rop protein Kelch_1 PF01344.20 EMC85031.1 - 5.1e-71 234.0 7.6 1.2e-14 53.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC85031.1 - 9.1e-46 152.2 4.1 1.2e-08 34.7 0.0 6.5 4 1 2 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EMC85031.1 - 1.6e-31 107.7 8.7 1.1e-06 28.6 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC85031.1 - 2.4e-30 103.1 8.4 8.3e-06 25.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.10 EMC85031.1 - 3.7e-28 97.3 0.6 3.7e-28 97.3 0.4 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 EMC85031.1 - 1.8e-25 88.4 7.9 5.6e-06 26.0 0.0 6.7 6 1 1 7 7 7 5 Galactose oxidase, central domain BTB PF00651.26 EMC85031.1 - 6.3e-25 87.3 1.6 6.3e-25 87.3 1.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 EMC85031.1 - 4.6e-08 32.8 7.5 0.56 10.2 0.0 5.9 6 0 0 6 6 6 3 Kelch motif AF-4 PF05110.8 EMC85032.1 - 0 1234.4 98.6 0 1234.2 68.4 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein ANKH PF07260.6 EMC85032.1 - 0.31 10.0 0.0 0.49 9.3 0.0 1.2 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) PDZ PF00595.19 EMC85033.1 - 1.5e-76 252.5 5.7 1.9e-18 66.4 0.6 5.5 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) Y_phosphatase PF00102.22 EMC85033.1 - 3.3e-74 249.1 0.0 5.9e-74 248.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.13 EMC85033.1 - 3.6e-24 85.3 2.1 3.6e-24 85.3 1.4 2.2 2 0 0 2 2 2 1 FERM central domain PDZ_2 PF13180.1 EMC85033.1 - 4.3e-21 74.6 1.9 0.00016 21.5 0.0 5.3 5 0 0 5 5 5 4 PDZ domain FERM_C PF09380.5 EMC85033.1 - 2.1e-19 69.4 1.4 1e-18 67.3 0.3 2.3 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 EMC85033.1 - 2.7e-19 68.9 1.0 1.4e-18 66.7 0.3 2.7 3 0 0 3 3 3 1 FERM N-terminal domain DSPc PF00782.15 EMC85033.1 - 0.00055 19.5 0.4 0.002 17.7 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC85033.1 - 0.02 14.9 0.0 0.088 12.8 0.0 2.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Pkinase PF00069.20 EMC85034.1 - 7e-67 225.3 0.0 8.8e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85034.1 - 5.2e-31 107.6 0.1 7.2e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC85034.1 - 3.8e-07 29.3 0.1 5.9e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC85034.1 - 0.00019 20.5 0.1 0.00034 19.6 0.1 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC85034.1 - 0.00022 20.6 0.3 0.00044 19.6 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMC85034.1 - 0.00045 20.0 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RhoGAP PF00620.22 EMC85035.1 - 2.1e-49 167.0 0.0 4.9e-49 165.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Tropomyosin_1 PF12718.2 EMC85035.1 - 0.0091 15.8 11.5 0.018 14.8 8.0 1.4 1 0 0 1 1 1 1 Tropomyosin like DUF2748 PF10871.3 EMC85035.1 - 0.041 12.2 0.2 4.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) PAH PF02671.16 EMC85035.1 - 0.055 13.0 0.3 0.58 9.8 0.1 2.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat PH PF00169.24 EMC85035.1 - 0.1 12.7 2.8 0.17 12.0 0.0 2.5 2 1 0 2 2 2 0 PH domain DMPK_coil PF08826.5 EMC85035.1 - 2.8 7.9 16.3 4.2 7.3 4.8 2.9 1 1 1 2 2 2 0 DMPK coiled coil domain like IncA PF04156.9 EMC85035.1 - 3.1 7.3 13.0 3.8 7.0 7.5 2.1 2 1 0 2 2 2 0 IncA protein PCI PF01399.22 EMC85037.1 - 4.6e-18 65.4 3.1 1e-17 64.3 0.0 2.7 3 1 0 3 3 3 1 PCI domain TPR_12 PF13424.1 EMC85037.1 - 0.0031 17.3 4.3 0.22 11.5 1.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC85037.1 - 0.012 15.3 1.5 1.3 8.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 EMC85037.1 - 0.017 14.5 0.8 0.031 13.6 0.6 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_14 PF13428.1 EMC85037.1 - 0.15 12.7 0.1 0.15 12.7 0.1 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF972 PF06156.8 EMC85037.1 - 0.94 9.8 7.1 3.7 7.9 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF972) TPR_19 PF14559.1 EMC85037.1 - 1.7 9.0 7.9 0.38 11.1 1.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TCR PF03638.10 EMC85038.1 - 3.9e-24 84.2 55.7 6.7e-13 48.2 15.3 2.6 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain DUF3735 PF12537.3 EMC85039.1 - 0.14 12.2 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) FA_desaturase PF00487.19 EMC85040.1 - 2.5e-19 69.7 10.6 3.6e-19 69.2 7.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase UbiA PF01040.13 EMC85040.1 - 0.0042 16.3 1.3 0.58 9.3 0.1 2.2 2 0 0 2 2 2 2 UbiA prenyltransferase family PetL PF05115.9 EMC85040.1 - 0.34 10.8 3.6 0.43 10.5 1.1 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Frag1 PF10277.4 EMC85041.1 - 2.4e-44 151.3 7.5 2.9e-44 151.1 5.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 EMC85041.1 - 0.00081 18.7 6.7 0.00081 18.7 4.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF202 PF02656.10 EMC85041.1 - 0.86 9.8 6.3 5 7.4 1.1 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF202) HAD_2 PF13419.1 EMC85042.1 - 3.6e-20 72.9 0.0 4.8e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 EMC85043.1 - 8.5e-40 134.2 0.1 9.2e-19 66.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC85043.1 - 4.7e-31 106.5 0.0 1.5e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85043.1 - 8.1e-12 44.8 0.0 8.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC85043.1 - 2.2e-05 24.2 0.2 0.012 15.4 0.0 2.7 2 2 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EMC85043.1 - 0.00033 20.3 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 EMC85043.1 - 0.018 15.0 0.8 1.6 8.8 0.0 3.1 4 0 0 4 4 4 0 Nmi/IFP 35 domain (NID) API5 PF05918.6 EMC85043.1 - 8.4 4.7 6.6 12 4.2 4.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pkinase PF00069.20 EMC85044.1 - 3.9e-69 232.7 0.4 2e-67 227.0 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain cNMP_binding PF00027.24 EMC85044.1 - 1.3e-38 130.6 0.3 2.8e-19 68.6 0.1 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 EMC85044.1 - 3.1e-34 118.2 0.0 6.8e-33 113.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC85044.1 - 6.3e-05 22.0 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.6 EMC85044.1 - 0.0044 16.8 4.8 0.01 15.6 3.3 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APH PF01636.18 EMC85044.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Antigen_Bd37 PF11641.3 EMC85044.1 - 0.13 11.5 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Reo_sigmaC PF04582.7 EMC85044.1 - 0.15 11.1 0.4 0.25 10.4 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 EMC85044.1 - 0.17 11.4 7.8 0.4 10.2 5.4 1.6 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 EMC85044.1 - 0.17 11.0 5.5 0.37 9.9 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RasGEF PF00617.14 EMC85045.1 - 3e-51 173.8 0.9 5.5e-51 172.9 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EMC85045.1 - 6.4e-17 61.5 0.4 1.8e-16 60.1 0.1 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif TGF_beta PF00019.15 EMC85046.1 - 1.6e-36 124.7 0.1 3.1e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain FGF PF00167.13 EMC85047.1 - 1.5e-40 137.7 0.0 1.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Ant_C PF05586.6 EMC85048.1 - 9e-42 141.4 0.3 2e-41 140.3 0.2 1.6 1 0 0 1 1 1 1 Anthrax receptor C-terminus region Anth_Ig PF05587.8 EMC85048.1 - 1.3e-37 127.7 0.5 2e-37 127.2 0.3 1.3 1 0 0 1 1 1 1 Anthrax receptor extracellular domain VWA PF00092.23 EMC85048.1 - 4.5e-08 33.0 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3328 PF11807.3 EMC85048.1 - 0.031 13.9 0.2 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) 4HBT_3 PF13622.1 EMC85048.1 - 0.11 12.1 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily HlyIII PF03006.15 EMC85050.1 - 5.1e-44 150.3 24.9 6.2e-44 150.0 17.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.20 EMC85051.1 - 2.7e-40 138.1 0.0 5.5e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85051.1 - 2.2e-25 89.1 0.0 2.2e-25 89.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC85051.1 - 3.4e-08 32.7 0.5 8.1e-07 28.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC85051.1 - 0.00048 19.9 4.3 0.048 13.3 0.0 3.1 2 2 1 3 3 3 2 Phosphotransferase enzyme family Med15 PF09606.5 EMC85051.1 - 0.92 7.6 44.1 1.3 7.1 30.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NTF2 PF02136.15 EMC85052.1 - 2.8e-32 111.5 0.1 4.5e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EMC85052.1 - 1.2e-14 53.6 0.1 2.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC85052.1 - 2.3e-10 40.3 0.1 5.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85052.1 - 0.005 16.6 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EGF PF00008.22 EMC85053.1 - 0.00087 19.2 3.6 0.0017 18.2 2.5 1.6 1 0 0 1 1 1 1 EGF-like domain Chordopox_A33R PF05966.7 EMC85053.1 - 0.018 13.8 1.0 0.018 13.8 0.7 1.5 1 1 0 1 1 1 0 Chordopoxvirus A33R protein EphA2_TM PF14575.1 EMC85053.1 - 0.034 14.5 0.3 0.034 14.5 0.2 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EMC85053.1 - 0.035 13.8 0.2 0.035 13.8 0.2 1.8 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.6 EMC85053.1 - 0.077 12.5 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Podoplanin Protocadherin PF08374.6 EMC85053.1 - 0.46 10.0 7.2 0.13 11.8 0.2 2.1 2 0 0 2 2 2 0 Protocadherin EGF_2 PF07974.8 EMC85053.1 - 0.6 10.3 5.2 1.1 9.4 3.6 1.5 1 0 0 1 1 1 0 EGF-like domain Anophelin PF10731.4 EMC85053.1 - 1.3 9.1 3.5 5.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito EGF PF00008.22 EMC85054.1 - 5.8e-06 26.1 3.0 1.1e-05 25.2 2.1 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 EMC85054.1 - 0.0094 15.9 1.4 0.0094 15.9 1.0 2.1 2 0 0 2 2 2 1 Human growth factor-like EGF DUF3139 PF11337.3 EMC85054.1 - 0.011 15.9 0.4 0.016 15.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) CD34_antigen PF06365.7 EMC85054.1 - 0.067 12.8 0.3 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Rifin_STEVOR PF02009.11 EMC85054.1 - 0.091 12.3 1.7 0.11 12.0 1.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF2207 PF09972.4 EMC85054.1 - 0.13 10.7 0.1 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PMP1_2 PF08114.6 EMC85054.1 - 0.2 11.1 1.5 0.32 10.5 1.0 1.3 1 0 0 1 1 1 0 ATPase proteolipid family EGF PF00008.22 EMC85055.1 - 0.071 13.0 3.9 0.14 12.1 2.7 1.6 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.19 EMC85055.1 - 0.42 10.5 2.7 0.93 9.4 1.9 1.6 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) THF_DHG_CYH_C PF02882.14 EMC85056.1 - 1.4e-61 206.2 3.1 1.9e-61 205.8 2.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMC85056.1 - 1.3e-38 131.6 0.2 1.9e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IL8 PF00048.15 EMC85057.1 - 1.9e-16 59.7 0.1 2.1e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 EMC85058.1 - 2.9e-21 75.1 0.7 3.9e-21 74.7 0.5 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ig_J_chain PF15097.1 EMC85058.1 - 0.023 14.2 0.1 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin J chain bPH_6 PF10756.4 EMC85058.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain IL8 PF00048.15 EMC85059.1 - 1e-18 67.0 0.5 1.4e-18 66.6 0.4 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like RA PF00788.18 EMC85060.1 - 2.8e-11 43.7 0.0 6.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain YusW PF14039.1 EMC85060.1 - 0.06 13.6 2.0 0.086 13.1 0.0 2.3 3 0 0 3 3 3 0 YusW-like protein Serum_albumin PF00273.15 EMC85061.1 - 2.1e-137 454.0 28.7 4.6e-55 185.7 5.9 3.3 3 1 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.5 EMC85061.1 - 0.013 15.1 15.9 0.9 9.1 0.0 5.9 6 0 0 6 6 6 0 Vitamin D binding protein, domain III DUF2633 PF11119.3 EMC85061.1 - 0.58 9.9 2.3 1.3 8.8 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Ank_2 PF12796.2 EMC85062.1 - 8.8e-213 689.4 67.7 2.6e-25 88.5 0.7 12.2 3 3 9 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 EMC85062.1 - 3.3e-178 569.4 64.3 8.4e-11 41.1 0.0 25.4 25 0 0 25 25 25 24 Ankyrin repeat Ank_4 PF13637.1 EMC85062.1 - 5.9e-140 453.5 17.0 5.8e-13 48.9 0.0 14.5 9 4 3 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC85062.1 - 3.6e-120 379.6 38.3 9.8e-05 22.2 0.1 25.2 25 0 0 25 25 25 24 Ankyrin repeat Ank_5 PF13857.1 EMC85062.1 - 1.6e-107 349.1 52.2 4.4e-09 36.2 0.4 23.6 3 3 22 25 25 25 25 Ankyrin repeats (many copies) KH_1 PF00013.24 EMC85062.1 - 1.9e-14 53.0 3.8 4.7e-14 51.7 2.6 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC85062.1 - 7.7e-11 41.3 5.3 2.3e-10 39.8 3.7 1.9 1 0 0 1 1 1 1 KH domain 60KD_IMP PF02096.15 EMC85063.1 - 1.8e-29 102.8 0.1 2.2e-29 102.5 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Pep_M12B_propep PF01562.14 EMC85064.1 - 3.2e-34 117.5 0.0 6.8e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.9 EMC85064.1 - 1.6e-31 108.4 0.0 3.4e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 EMC85064.1 - 2.2e-22 78.9 60.6 6.8e-10 38.9 4.1 5.9 6 0 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.14 EMC85064.1 - 1.8e-20 73.3 0.0 3.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 EMC85064.1 - 1.6e-14 54.2 0.9 4.6e-14 52.8 0.6 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC85064.1 - 1.9e-11 44.5 0.4 5e-11 43.2 0.3 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC85064.1 - 2.8e-11 43.7 3.4 9e-11 42.1 0.9 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC85064.1 - 4e-10 39.5 0.3 4.1e-09 36.2 0.2 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 EMC85064.1 - 7e-05 23.0 4.8 0.00047 20.3 3.3 2.6 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.19 EMC85064.1 - 0.0012 18.5 0.7 0.0023 17.6 0.1 1.8 2 0 0 2 2 2 1 Matrixin Neocarzinostat PF00960.13 EMC85066.1 - 1.8 8.5 10.1 0.45 10.4 0.9 2.9 2 1 1 3 3 3 0 Neocarzinostatin family Vanabin-2 PF11437.3 EMC85066.1 - 2.7 8.0 11.8 1.2 9.1 2.2 2.4 2 0 0 2 2 2 0 Vanadium-binding protein 2 EF-hand_1 PF00036.27 EMC85067.1 - 6.6e-14 50.0 2.3 9.4e-05 21.4 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 EMC85067.1 - 3.1e-13 48.3 0.4 0.00012 21.6 0.0 3.7 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.1 EMC85067.1 - 4.9e-12 44.5 4.1 4.9e-05 22.4 0.1 4.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EMC85067.1 - 5.4e-11 42.4 1.7 0.014 15.5 0.0 3.3 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC85067.1 - 2.5e-09 36.5 2.7 0.00084 18.9 0.2 3.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.2 EMC85067.1 - 0.0014 18.3 0.0 0.012 15.3 0.0 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC85067.1 - 0.0063 16.4 0.1 2.5 8.0 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EMC85067.1 - 0.0095 15.9 0.3 4.7 7.2 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EMC85067.1 - 0.043 13.4 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 EF hand 7tm_4 PF13853.1 EMC85069.1 - 2.5e-15 56.5 0.1 2.9e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 Olfactory receptor SDF PF00375.13 EMC85070.1 - 2.6e-137 457.7 32.2 3e-137 457.5 22.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.2 EMC85070.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Nipped-B_C PF12830.2 EMC85072.1 - 1.4e-63 213.9 5.9 2.1e-62 210.1 0.7 4.1 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EMC85072.1 - 8.3e-13 47.9 8.9 1.1e-12 47.6 0.2 3.7 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EMC85072.1 - 6.8e-10 39.1 0.6 0.094 13.0 0.0 6.1 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EMC85072.1 - 9.1e-07 28.4 1.8 0.23 11.6 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EMC85072.1 - 9.2e-05 22.8 0.1 0.19 12.2 0.0 5.1 5 1 0 6 6 6 1 HEAT-like repeat WD40 PF00400.27 EMC85073.1 - 9.4e-22 76.0 14.9 0.00028 20.6 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat TGF_beta PF00019.15 EMC85074.1 - 4.3e-18 65.5 0.9 6.1e-18 65.0 0.7 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain Hamartin PF04388.7 EMC85074.1 - 0.05 12.2 0.0 0.05 12.2 0.0 1.1 1 0 0 1 1 1 0 Hamartin protein Laminin_G_2 PF02210.19 EMC85075.1 - 1.7e-84 280.2 0.2 2e-27 95.7 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 EMC85075.1 - 6.7e-83 275.2 0.0 1.1e-26 93.4 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain fn3 PF00041.16 EMC85075.1 - 3.4e-24 84.7 0.2 2.2e-13 50.1 0.2 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Laminin_G_3 PF13385.1 EMC85075.1 - 1.1e-13 51.7 0.1 0.00083 19.6 0.0 3.4 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 EMC85075.1 - 1.5e-08 34.4 34.3 6.5e-07 29.1 4.9 3.5 3 0 0 3 3 3 2 EGF-like domain Stirrup PF09061.1 EMC85075.1 - 1.9e-06 27.6 0.1 0.039 13.8 0.0 3.3 3 0 0 3 3 3 2 Stirrup hEGF PF12661.2 EMC85075.1 - 0.0063 16.5 17.0 0.12 12.4 0.8 3.7 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.8 EMC85075.1 - 0.84 9.8 40.9 0.31 11.2 6.7 3.9 3 1 0 3 3 3 0 EGF-like domain EGF_CA PF07645.10 EMC85075.1 - 5.2 7.1 37.8 0.48 10.4 4.2 3.5 3 0 0 3 3 3 0 Calcium-binding EGF domain fn3 PF00041.16 EMC85076.1 - 3.7e-19 68.6 3.1 5.6e-05 23.1 0.0 6.3 6 1 0 6 6 6 4 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC85076.1 - 8.9e-09 35.4 3.1 0.0023 18.0 0.0 3.6 4 0 0 4 4 4 2 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 EMC85076.1 - 1e-05 25.4 0.6 0.0079 16.1 0.1 2.6 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding CD34_antigen PF06365.7 EMC85076.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family fn3 PF00041.16 EMC85077.1 - 1.8e-17 63.2 7.7 5.9e-06 26.3 0.1 5.0 5 0 0 5 5 5 4 Fibronectin type III domain PKD PF00801.15 EMC85077.1 - 0.032 13.9 0.2 0.31 10.8 0.0 2.6 2 1 0 2 2 2 0 PKD domain IL6Ra-bind PF09240.5 EMC85077.1 - 0.73 10.0 11.1 0.79 9.9 0.2 3.7 2 1 0 3 3 3 0 Interleukin-6 receptor alpha chain, binding RICTOR_N PF14664.1 EMC85078.1 - 1.4e-118 395.7 1.5 2.4e-118 394.9 1.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EMC85078.1 - 6.7e-64 214.9 3.2 6.7e-64 214.9 2.2 3.4 4 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_phospho PF14665.1 EMC85078.1 - 7.5e-49 164.5 1.3 7.5e-49 164.5 0.9 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site RasGEF_N_2 PF14663.1 EMC85078.1 - 5.9e-41 139.0 0.2 5.9e-41 139.0 0.1 2.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EMC85078.1 - 5.9e-33 112.6 5.8 8.6e-32 108.9 0.4 4.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EMC85078.1 - 0.00047 20.3 3.0 0.45 10.8 0.0 4.7 5 0 0 5 5 5 1 HEAT repeats 7TM_GPCR_Srbc PF10316.4 EMC85078.1 - 0.12 11.6 2.8 4.4 6.4 0.0 2.6 2 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc HEAT_EZ PF13513.1 EMC85078.1 - 0.26 11.8 2.3 15 6.1 0.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat hSH3 PF14603.1 EMC85079.1 - 7.6e-30 102.7 12.1 4.8e-24 84.1 0.0 4.8 4 1 1 5 5 5 2 Helically-extended SH3 domain SH3_2 PF07653.12 EMC85079.1 - 1.6e-06 27.5 0.5 3.5e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC85079.1 - 0.0037 16.6 0.3 0.84 9.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC85079.1 - 0.046 13.3 0.7 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Variant SH3 domain PID PF00640.18 EMC85080.1 - 1.7e-24 86.3 0.1 2.7e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MIP-T3 PF10243.4 EMC85081.1 - 0.0054 15.2 63.8 0.0064 15.0 44.2 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EMC85081.1 - 0.77 9.6 46.9 0.91 9.3 32.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EMC85081.1 - 0.91 8.8 52.4 1.2 8.4 36.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) 7tm_1 PF00001.16 EMC85082.1 - 1.4e-44 152.1 12.2 1.7e-44 151.8 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC85082.1 - 2.1e-07 30.3 15.6 2.8e-07 29.9 10.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx EIIC-GAT PF03611.9 EMC85082.1 - 0.0011 17.8 2.6 0.0067 15.2 0.2 2.1 2 0 0 2 2 2 1 PTS system sugar-specific permease component NdhL PF10716.4 EMC85082.1 - 0.0016 18.2 0.7 0.0059 16.3 0.0 2.3 2 0 0 2 2 2 1 NADH dehydrogenase transmembrane subunit RecO_N_2 PF13114.1 EMC85083.1 - 0.029 14.0 0.1 0.063 12.9 0.0 1.6 2 0 0 2 2 2 0 RecO N terminal TPR_11 PF13414.1 EMC85084.1 - 5.2e-14 51.6 0.1 1e-10 41.0 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC85084.1 - 1.3e-09 37.2 0.0 0.00032 20.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC85084.1 - 1.9e-08 34.7 0.2 0.0053 17.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC85084.1 - 1.3e-06 28.4 0.7 0.11 13.1 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC85084.1 - 1.3e-05 25.0 0.0 0.018 15.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC85084.1 - 5.3e-05 22.6 0.0 0.24 11.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC85084.1 - 7.5e-05 22.5 1.1 0.17 11.7 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC85084.1 - 0.00014 22.1 0.0 0.025 14.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 EMC85084.1 - 0.0029 16.4 0.3 0.0035 16.1 0.2 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 EMC85084.1 - 0.0079 16.1 0.2 1.1 9.2 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat CUE PF02845.11 EMC85084.1 - 0.26 10.8 1.0 0.96 9.0 0.0 2.4 3 0 0 3 3 3 0 CUE domain DUF4110 PF13422.1 EMC85084.1 - 9.1 6.2 8.3 5.1 6.9 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) Pkinase PF00069.20 EMC85085.1 - 1e-74 250.9 0.0 1.4e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85085.1 - 1.2e-41 142.4 0.0 1.7e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC85085.1 - 5.5e-05 22.2 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC85085.1 - 0.00075 18.8 0.2 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMC85085.1 - 0.0032 16.5 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC85085.1 - 0.073 12.7 0.2 0.26 10.9 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.2 EMC85086.1 - 3.4e-07 29.8 1.2 1e-06 28.3 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC85086.1 - 3.9e-06 26.3 0.8 1.2e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 F-box domain CoA_trans PF01144.18 EMC85088.1 - 1.6e-123 409.9 1.1 2e-74 249.4 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EMC85088.1 - 0.0024 17.5 0.1 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RVT_1 PF00078.22 EMC85089.1 - 0.033 13.5 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PI-PLC-X PF00388.14 EMC85090.1 - 2.7e-07 30.0 0.0 3.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MACPF PF01823.14 EMC85091.1 - 3.4e-46 157.6 3.7 7e-46 156.5 1.5 2.0 2 0 0 2 2 2 1 MAC/Perforin domain Sushi PF00084.15 EMC85091.1 - 8.3e-15 54.8 7.2 2.2e-08 34.2 0.7 5.0 6 0 0 6 6 6 2 Sushi domain (SCR repeat) TSP_1 PF00090.14 EMC85091.1 - 1.3e-12 47.6 29.0 1.1e-07 31.8 5.3 5.9 5 0 0 5 5 5 3 Thrombospondin type 1 domain Ldl_recept_a PF00057.13 EMC85091.1 - 1.2e-10 41.0 13.2 1.2e-10 41.0 9.1 3.9 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A MACPF PF01823.14 EMC85092.1 - 5.3e-48 163.5 0.8 5.3e-48 163.5 0.5 1.7 1 1 1 2 2 2 1 MAC/Perforin domain Sushi PF00084.15 EMC85092.1 - 1.4e-13 50.9 1.5 1.1e-09 38.4 0.4 4.4 4 0 0 4 4 4 2 Sushi domain (SCR repeat) Ldl_recept_a PF00057.13 EMC85092.1 - 1.5e-07 31.2 14.6 1.5e-07 31.2 10.1 3.9 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 EMC85092.1 - 4.7e-07 29.8 22.8 6.1e-05 23.0 2.3 5.4 6 0 0 6 6 6 2 Thrombospondin type 1 domain Ribosomal_L37e PF01907.14 EMC85093.1 - 7.9e-25 86.4 15.3 1.3e-24 85.7 10.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EMC85093.1 - 0.0023 17.6 2.4 0.0037 17.0 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon FeS PF04060.8 EMC85093.1 - 0.011 15.3 2.1 0.013 15.0 0.1 2.0 2 0 0 2 2 2 0 Putative Fe-S cluster zf-NADH-PPase PF09297.6 EMC85093.1 - 0.032 13.7 2.5 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain FYDLN_acid PF09538.5 EMC85093.1 - 0.16 12.5 1.4 0.16 12.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GFA PF04828.9 EMC85093.1 - 0.34 10.8 4.1 0.88 9.5 0.3 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 EMC85093.1 - 0.79 9.5 5.9 1.8 8.4 4.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a zinc_ribbon_2 PF13240.1 EMC85093.1 - 0.8 9.2 4.3 11 5.5 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2688 PF10892.3 EMC85093.1 - 1 9.0 3.5 6.3 6.5 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Ras PF00071.17 EMC85096.1 - 1.6e-58 196.6 0.1 1.9e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC85096.1 - 6.8e-19 68.5 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC85096.1 - 2.1e-13 49.8 0.1 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC85096.1 - 2e-07 30.9 0.0 3.7e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC85096.1 - 5.3e-07 29.0 0.0 6.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC85096.1 - 1.6e-06 27.7 0.0 4.6e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMC85096.1 - 0.00029 20.9 0.0 0.00058 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMC85096.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EMC85096.1 - 0.0012 17.9 0.3 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Septin NTPase_1 PF03266.10 EMC85096.1 - 0.0027 17.4 0.1 0.0051 16.5 0.0 1.5 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.4 EMC85096.1 - 0.0035 16.8 0.1 0.088 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EMC85096.1 - 0.0038 16.6 0.1 0.016 14.6 0.0 1.9 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EMC85096.1 - 0.0042 16.6 0.4 0.15 11.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EMC85096.1 - 0.0052 16.5 0.5 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 EMC85096.1 - 0.0052 16.3 0.1 0.0097 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC85096.1 - 0.0074 16.2 0.1 0.037 14.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EMC85096.1 - 0.01 15.5 0.1 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EMC85096.1 - 0.011 15.3 0.0 0.035 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EMC85096.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EMC85096.1 - 0.018 14.4 0.2 0.028 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain NACHT PF05729.7 EMC85096.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EMC85096.1 - 0.074 12.9 0.2 0.15 11.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EMC85096.1 - 0.15 12.4 0.1 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Ribophorin_I PF04597.9 EMC85097.1 - 2.6e-138 461.1 7.6 3.5e-138 460.7 5.3 1.2 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.1 EMC85097.1 - 0.0042 17.4 0.8 0.0077 16.5 0.2 1.7 2 0 0 2 2 2 1 DNA repair REX1-B HALZ PF02183.13 EMC85097.1 - 0.15 11.8 3.0 0.1 12.3 0.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper GATA PF00320.22 EMC85098.1 - 6.5e-32 108.5 19.3 5.4e-16 57.6 4.3 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EMC85098.1 - 0.00015 20.9 9.9 0.044 13.1 0.3 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Prim_Zn_Ribbon PF08273.7 EMC85098.1 - 0.031 14.3 1.9 0.031 14.3 1.3 3.0 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2387 PF09526.5 EMC85098.1 - 0.065 13.1 9.0 3.3 7.6 1.4 3.1 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.12 EMC85098.1 - 0.22 11.1 7.6 4.3 7.0 1.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Prok-RING_2 PF14445.1 EMC85098.1 - 1.7 8.6 7.0 0.15 12.0 0.7 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Zn-ribbon_8 PF09723.5 EMC85098.1 - 2.6 8.0 9.4 1.8 8.5 0.4 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EMC85098.1 - 4.8 6.5 11.2 6.7 6.0 0.8 3.4 3 1 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EMC85098.1 - 4.9 7.0 16.5 3.7 7.4 1.2 3.1 1 1 2 3 3 3 0 Double zinc ribbon DnaJ PF00226.26 EMC85099.1 - 1.2e-26 92.1 2.9 1.3e-26 92.0 2.0 1.0 1 0 0 1 1 1 1 DnaJ domain Enkurin PF13864.1 EMC85099.1 - 0.062 13.5 0.2 0.065 13.4 0.1 1.0 1 0 0 1 1 1 0 Calmodulin-binding GTP_EFTU PF00009.22 EMC85100.1 - 1e-09 38.0 0.1 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EMC85100.1 - 1.1e-09 38.2 0.1 2.3e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.14 EMC85100.1 - 0.00016 21.1 0.6 0.00025 20.5 0.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.1 EMC85100.1 - 0.00076 19.0 0.1 0.0023 17.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 TIP49 PF06068.8 EMC85101.1 - 2.5e-194 645.5 0.5 2.9e-194 645.3 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EMC85101.1 - 1.1e-13 50.7 2.1 4.4e-08 32.4 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EMC85101.1 - 6e-13 49.1 0.6 2.8e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMC85101.1 - 2e-07 31.1 0.0 0.00091 19.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EMC85101.1 - 3.2e-06 27.3 0.1 0.035 14.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMC85101.1 - 1.4e-05 24.7 0.0 3.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EMC85101.1 - 5.2e-05 22.9 0.1 0.0033 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMC85101.1 - 5.5e-05 22.6 0.0 0.00014 21.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EMC85101.1 - 0.00017 21.1 0.1 0.18 11.2 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMC85101.1 - 0.00055 19.4 0.1 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMC85101.1 - 0.00062 18.9 0.2 0.031 13.4 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EMC85101.1 - 0.00075 18.6 0.6 0.0015 17.6 0.2 1.6 2 0 0 2 2 1 1 Zeta toxin AAA_18 PF13238.1 EMC85101.1 - 0.0014 18.9 0.8 0.017 15.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EMC85101.1 - 0.0018 19.0 0.0 0.0046 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMC85101.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC85101.1 - 0.0039 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EMC85101.1 - 0.0066 15.6 0.1 0.02 14.1 0.1 1.8 1 0 0 1 1 1 1 PhoH-like protein DnaB_C PF03796.10 EMC85101.1 - 0.0079 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_14 PF13173.1 EMC85101.1 - 0.0098 15.7 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMC85101.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 EMC85101.1 - 0.015 14.1 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EMC85101.1 - 0.017 14.7 0.0 0.058 13.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EMC85101.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EMC85101.1 - 0.031 13.2 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EMC85101.1 - 0.038 13.6 0.1 0.099 12.3 0.0 1.8 2 0 0 2 2 1 0 NTPase DNA_pol3_delta2 PF13177.1 EMC85101.1 - 0.039 13.6 0.1 2.2 7.9 0.0 2.3 2 1 0 2 2 2 0 DNA polymerase III, delta subunit ResIII PF04851.10 EMC85101.1 - 0.045 13.5 0.1 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EMC85101.1 - 0.052 12.6 1.6 0.17 10.9 0.0 2.4 3 0 0 3 3 3 0 KaiC T2SE PF00437.15 EMC85101.1 - 0.072 11.9 0.3 0.48 9.2 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EMC85101.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SecY PF00344.15 EMC85102.1 - 2.5e-96 322.6 13.7 3.5e-96 322.1 9.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMC85102.1 - 1.4e-19 69.2 0.3 4.2e-19 67.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_holin_1 PF04531.8 EMC85102.1 - 0.035 14.1 0.1 3.3 7.8 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin YlaH PF14036.1 EMC85102.1 - 0.035 14.1 3.1 0.46 10.5 0.1 3.1 3 0 0 3 3 3 0 YlaH-like protein Kelch_1 PF01344.20 EMC85103.1 - 2.8e-29 100.3 2.6 6.3e-12 44.8 0.0 4.8 4 1 0 4 4 4 4 Kelch motif BACK PF07707.10 EMC85103.1 - 3.2e-29 100.7 2.5 3.2e-29 100.7 1.7 2.9 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 EMC85103.1 - 5.9e-25 86.3 2.8 5.5e-09 35.8 0.0 5.1 3 1 2 5 5 5 3 Kelch motif BTB PF00651.26 EMC85103.1 - 2.5e-23 82.1 1.4 2.5e-23 82.1 1.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 EMC85103.1 - 1.1e-13 50.3 2.9 4.8e-06 26.1 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EMC85103.1 - 5.3e-12 45.5 2.5 0.00056 19.9 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC85103.1 - 5.3e-11 42.1 5.5 7.2e-06 25.6 0.0 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC85103.1 - 9.9e-11 41.3 0.2 0.00013 21.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif DUF3342 PF11822.3 EMC85103.1 - 0.00024 20.3 1.0 0.00024 20.3 0.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) BTB PF00651.26 EMC85104.1 - 7.1e-44 148.3 2.8 3.5e-21 75.2 0.0 3.4 2 1 1 3 3 3 3 BTB/POZ domain Ank_5 PF13857.1 EMC85104.1 - 1.2e-10 41.2 0.2 6.5e-08 32.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC85104.1 - 1.6e-07 31.5 0.0 4.3e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC85104.1 - 3.8e-07 29.5 0.0 1.8e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EMC85104.1 - 3.3e-06 27.4 0.2 1.5e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC85104.1 - 1.1e-05 25.1 0.2 0.00025 20.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.3 EMC85104.1 - 0.00017 20.8 1.2 0.014 14.5 0.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) BACK PF07707.10 EMC85104.1 - 0.00056 19.7 0.1 0.0018 18.0 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch IFT20 PF14931.1 EMC85104.1 - 0.015 15.1 1.2 0.051 13.4 0.9 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 CD34_antigen PF06365.7 EMC85105.1 - 1.8e-62 210.6 0.0 2.3e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.1 EMC85105.1 - 0.15 12.1 0.5 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MCM PF00493.18 EMC85106.1 - 9e-142 471.7 0.0 1.3e-141 471.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EMC85106.1 - 7.3e-26 91.0 24.3 7.3e-26 91.0 16.8 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EMC85106.1 - 1.1e-19 71.0 0.7 3.1e-19 69.6 0.5 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC85106.1 - 1.1e-08 34.5 0.0 4.9e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMC85106.1 - 4.3e-07 29.5 0.0 3.4e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC85106.1 - 9.9e-07 28.5 0.0 2.8e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMC85106.1 - 0.0018 17.8 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 EMC85106.1 - 0.0024 18.0 0.0 0.007 16.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EMC85106.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 EMC85106.1 - 0.038 14.0 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Plexin_cytopl PF08337.7 EMC85107.1 - 2.3e-254 844.7 4.6 2.9e-254 844.4 3.2 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.14 EMC85107.1 - 2.7e-55 187.6 0.0 3.8e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Sema domain TIG PF01833.19 EMC85107.1 - 7.4e-45 150.8 14.6 1.1e-12 47.7 0.0 6.3 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 EMC85107.1 - 4.2e-21 74.8 54.7 5.1e-10 39.3 8.7 3.6 3 0 0 3 3 3 3 Plexin repeat YcbB PF08664.5 EMC85107.1 - 0.21 11.3 1.0 0.67 9.7 0.7 1.8 1 0 0 1 1 1 0 YcbB domain DUF948 PF06103.6 EMC85107.1 - 0.27 11.0 0.1 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0104 PF03706.8 EMC85107.1 - 0.35 10.0 0.0 0.59 9.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Pyr_redox_2 PF07992.9 EMC85108.1 - 5.5e-37 127.6 0.1 8.6e-37 126.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMC85108.1 - 7.8e-29 99.9 0.0 1.7e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glutaredoxin PF00462.19 EMC85108.1 - 1.1e-19 70.1 1.4 2.9e-19 68.8 0.1 2.5 3 0 0 3 3 3 1 Glutaredoxin Pyr_redox PF00070.22 EMC85108.1 - 7.6e-16 58.2 2.2 9.9e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC85108.1 - 3e-09 37.2 0.0 8.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC85108.1 - 2.5e-07 29.8 0.1 1.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EMC85108.1 - 0.00042 19.4 0.6 0.0023 17.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EMC85108.1 - 0.00073 18.1 0.2 0.0015 17.0 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EMC85108.1 - 0.0012 17.9 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thioredoxin_3 PF13192.1 EMC85108.1 - 0.0034 17.1 0.0 0.0092 15.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain DAO PF01266.19 EMC85108.1 - 0.0066 15.3 0.1 0.0066 15.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF836 PF05768.9 EMC85108.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GIDA PF01134.17 EMC85108.1 - 0.043 12.6 2.1 0.15 10.8 1.5 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EMC85108.1 - 0.075 13.0 0.4 0.075 13.0 0.3 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thioredoxin_7 PF13899.1 EMC85108.1 - 0.14 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like FAD_binding_3 PF01494.14 EMC85108.1 - 1.1 8.2 3.9 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Sulfotransfer_2 PF03567.9 EMC85109.1 - 6.3e-70 235.7 4.1 7.5e-70 235.4 2.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF4543 PF15076.1 EMC85109.1 - 0.0044 17.0 0.6 0.008 16.1 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) MgtE PF01769.11 EMC85110.1 - 2.1e-41 141.3 15.9 4.4e-27 95.0 5.4 3.4 3 1 1 4 4 4 2 Divalent cation transporter zf-H2C2_2 PF13465.1 EMC85112.1 - 0.00038 20.6 0.5 0.00038 20.6 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EMC85112.1 - 0.0058 16.9 5.6 0.0058 16.9 3.9 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type Spore_III_AF PF09581.5 EMC85112.1 - 0.095 12.5 1.2 0.15 11.9 0.8 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) zf-C2H2_4 PF13894.1 EMC85112.1 - 2 8.9 8.7 0.087 13.1 2.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4200 PF13863.1 EMC85113.1 - 8.7e-17 61.2 14.7 8.7e-17 61.2 10.2 5.8 5 2 1 6 6 6 2 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EMC85113.1 - 0.054 12.6 0.8 7.8 5.5 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein zf-C2H2 PF00096.21 EMC85114.1 - 5e-14 51.7 39.0 0.00059 20.0 0.2 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC85114.1 - 1.1e-11 44.1 30.8 0.0038 17.4 0.1 5.9 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC85114.1 - 3.9e-10 39.5 36.6 0.00043 20.4 0.0 6.4 6 1 1 7 7 7 3 Zinc-finger double domain zf-met PF12874.2 EMC85114.1 - 0.51 10.6 22.0 0.51 10.6 0.8 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Transpos_assoc PF13963.1 EMC85114.1 - 4.6 7.3 13.5 0.13 12.2 0.5 3.2 2 1 2 4 4 4 0 Transposase-associated domain Laminin_N PF00055.12 EMC85115.1 - 2.3e-46 157.7 0.0 3.6e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 EMC85115.1 - 6.4e-26 90.0 69.1 8.1e-10 38.4 6.8 6.1 5 1 1 6 6 6 4 Laminin EGF-like (Domains III and V) NTR PF01759.16 EMC85115.1 - 8.4e-21 73.6 0.2 2.2e-20 72.2 0.1 1.8 1 0 0 1 1 1 1 UNC-6/NTR/C345C module KGK PF08872.5 EMC85115.1 - 0.028 14.5 0.1 0.33 11.1 0.1 2.2 1 1 1 2 2 2 0 KGK domain DUF1625 PF07787.7 EMC85116.1 - 1.9e-82 276.2 0.0 2.4e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) BHD_3 PF10405.4 EMC85117.1 - 7.9e-31 105.5 0.0 1.9e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EMC85117.1 - 1.4e-26 92.6 1.1 1.4e-26 92.6 0.8 3.5 5 0 0 5 5 5 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 EMC85117.1 - 1.9e-18 66.5 0.2 1.9e-18 66.5 0.2 3.5 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EMC85117.1 - 2.6e-18 65.2 0.0 6.9e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 LSM PF01423.17 EMC85118.1 - 1.9e-19 68.9 0.2 2.6e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain vATP-synt_E PF01991.13 EMC85118.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit YfkB PF08756.5 EMC85118.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 YfkB-like domain DAN PF03045.10 EMC85119.1 - 0.13 11.6 0.1 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 DAN domain SNF PF00209.13 EMC85120.1 - 6.9e-236 783.7 37.9 8e-236 783.5 26.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PDZ PF00595.19 EMC85121.1 - 4.8e-95 311.8 3.0 4.3e-14 52.4 0.0 7.2 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC85121.1 - 6.3e-41 138.1 1.0 2.5e-05 24.0 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.1 EMC85121.1 - 1.6e-12 47.0 1.5 0.023 14.4 0.0 6.7 6 0 0 6 6 6 3 Tricorn protease PDZ domain GRASP55_65 PF04495.9 EMC85121.1 - 1.9e-05 24.6 0.0 4.2 7.3 0.0 4.8 4 1 1 5 5 5 2 GRASP55/65 PDZ-like domain MoaE PF02391.12 EMC85121.1 - 0.0039 16.9 1.2 9.6 6.0 0.0 4.2 5 0 0 5 5 5 2 MoaE protein EutA PF06277.6 EMC85121.1 - 0.02 13.4 0.2 0.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA DUF4078 PF13300.1 EMC85122.1 - 1.9e-23 82.3 8.2 1.9e-23 82.3 5.7 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4078) DUF4231 PF14015.1 EMC85124.1 - 0.11 12.5 0.3 0.55 10.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) NTPase_I-T PF01931.13 EMC85124.1 - 0.15 11.8 1.9 2.1 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF84 OEP PF02321.13 EMC85124.1 - 0.43 10.1 9.0 0.086 12.4 3.6 1.7 2 0 0 2 2 2 0 Outer membrane efflux protein T2SF PF00482.18 EMC85124.1 - 1.1 9.1 4.2 0.77 9.6 0.1 2.5 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F SseC PF04888.7 EMC85124.1 - 2 7.6 5.5 13 4.9 0.4 2.6 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family Plexin_cytopl PF08337.7 EMC85125.1 - 8.2e-253 839.6 0.0 1e-252 839.2 0.0 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 EMC85125.1 - 5.6e-34 116.0 0.0 5.7e-12 45.4 0.7 5.9 5 1 0 5 5 5 4 IPT/TIG domain Sema PF01403.14 EMC85125.1 - 6.9e-29 100.6 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 EMC85125.1 - 5.5e-16 58.4 50.3 1.9e-10 40.7 10.4 3.7 3 0 0 3 3 3 3 Plexin repeat Pkinase PF00069.20 EMC85126.1 - 7.6e-35 120.3 0.0 9.8e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85126.1 - 3.7e-14 52.4 0.0 2.2e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMC85126.1 - 0.078 11.7 0.1 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SET PF00856.23 EMC85127.1 - 2.6e-11 44.0 5.6 1.5e-10 41.5 0.1 4.0 3 1 0 3 3 3 1 SET domain Copine PF07002.11 EMC85128.1 - 3.8e-57 192.1 0.1 5.5e-57 191.6 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.25 EMC85128.1 - 3.1e-27 94.2 0.2 1.3e-13 50.5 0.1 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EMC85128.1 - 2.6e-09 37.1 0.0 4.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VCBS PF13517.1 EMC85128.1 - 0.0015 18.8 0.3 0.0078 16.5 0.2 2.3 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Pkinase PF00069.20 EMC85129.1 - 8.9e-33 113.5 0.6 9.8e-33 113.3 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85129.1 - 1.9e-19 69.7 0.3 2.1e-19 69.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMC85129.1 - 0.023 14.0 0.1 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Ada3 PF10198.4 EMC85131.1 - 1.5e-14 53.8 13.1 2.4e-09 37.0 0.9 3.2 2 1 1 3 3 3 2 Histone acetyltransferases subunit 3 DUF91 PF01939.11 EMC85131.1 - 0.029 13.5 1.0 0.05 12.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF91 PaaSYMP PF14738.1 EMC85131.1 - 0.14 11.8 7.4 0.08 12.6 3.1 2.0 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 SUZ PF12752.2 EMC85131.1 - 4.3 7.9 7.7 0.83 10.2 0.6 3.0 3 0 0 3 3 3 0 SUZ domain IL17_R_N PF15037.1 EMC85132.1 - 5.3e-83 279.2 9.1 6.6e-83 278.9 6.3 1.0 1 0 0 1 1 1 1 Interleukin-17 receptor extracellular region SEFIR PF08357.6 EMC85132.1 - 7.9e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 SEFIR domain EGF_CA PF07645.10 EMC85133.1 - 1.3e-09 37.8 8.3 2.1e-09 37.1 5.7 1.3 1 0 0 1 1 1 1 Calcium-binding EGF domain TIL PF01826.12 EMC85133.1 - 0.0074 16.3 8.1 0.01 15.9 5.6 1.2 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.2 EMC85133.1 - 0.03 14.2 3.7 0.054 13.4 2.5 1.6 1 1 0 1 1 1 0 EGF domain cEGF PF12662.2 EMC85133.1 - 0.066 12.8 1.4 0.066 12.8 1.0 2.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF PF00008.22 EMC85133.1 - 0.1 12.5 2.4 0.11 12.5 0.7 1.8 1 1 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.1 EMC85133.1 - 0.17 12.0 5.9 0.3 11.2 4.1 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 EMC85133.1 - 0.58 10.3 6.1 0.28 11.3 1.9 2.0 1 1 1 2 2 2 0 EGF-like domain EB PF01683.13 EMC85133.1 - 2.5 8.2 8.7 3.8 7.6 6.0 1.3 1 0 0 1 1 1 0 EB module AAA_13 PF13166.1 EMC85135.1 - 5.2e-05 21.9 2.6 6.5e-05 21.6 1.8 1.0 1 0 0 1 1 1 1 AAA domain Prominin PF05478.6 EMC85135.1 - 0.013 13.1 2.6 0.015 12.8 1.8 1.1 1 0 0 1 1 1 0 Prominin Reo_sigmaC PF04582.7 EMC85135.1 - 0.018 14.2 3.1 0.041 13.0 2.0 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF1640 PF07798.6 EMC85135.1 - 0.026 14.5 4.1 0.065 13.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Laminin_II PF06009.7 EMC85135.1 - 0.06 13.1 2.3 2.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.6 EMC85135.1 - 0.073 12.8 8.6 0.12 12.1 5.6 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HR1 PF02185.11 EMC85135.1 - 0.083 12.6 5.9 0.091 12.5 3.0 2.0 2 0 0 2 2 2 0 Hr1 repeat DUF3919 PF13057.1 EMC85135.1 - 0.084 12.3 0.4 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) FlaC_arch PF05377.6 EMC85135.1 - 0.12 12.3 0.8 8.3 6.4 0.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 EMC85135.1 - 0.12 11.8 0.4 0.25 10.8 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Fib_alpha PF08702.5 EMC85135.1 - 0.13 12.3 5.2 0.23 11.6 3.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 EMC85135.1 - 0.2 11.5 5.7 0.45 10.3 1.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3972 PF13118.1 EMC85135.1 - 0.31 11.1 3.7 1.1 9.3 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) Tropomyosin_1 PF12718.2 EMC85135.1 - 0.43 10.4 9.1 0.041 13.7 2.1 2.2 2 1 1 3 3 3 0 Tropomyosin like Baculo_PEP_C PF04513.7 EMC85135.1 - 0.59 9.9 3.2 3.1 7.6 1.8 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.4 EMC85135.1 - 1.6 8.0 7.4 2.8 7.2 4.9 1.6 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 EMC85135.1 - 2.5 7.6 11.4 5 6.6 7.9 1.7 1 1 0 1 1 1 0 IncA protein CCDC71L PF15374.1 EMC85136.1 - 1.3e-155 518.3 17.3 1.5e-155 518.1 12.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L TraV PF09676.5 EMC85136.1 - 1.3 9.7 7.1 3.4 8.4 0.1 2.7 3 0 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) Laminin_EGF PF00053.19 EMC85137.1 - 8.9e-97 316.8 235.9 1.7e-11 43.8 4.7 12.1 10 2 2 12 12 12 11 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EMC85137.1 - 0.0024 17.8 5.5 0.0024 17.8 3.8 16.6 19 0 0 19 19 19 2 Human growth factor-like EGF Laminin_II PF06009.7 EMC85137.1 - 0.0027 17.4 0.4 0.0027 17.4 0.3 3.4 3 0 0 3 3 3 1 Laminin Domain II IncA PF04156.9 EMC85137.1 - 0.0074 15.9 0.5 0.0074 15.9 0.4 3.2 3 0 0 3 3 3 1 IncA protein Tropomyosin_1 PF12718.2 EMC85137.1 - 0.03 14.1 23.5 0.18 11.6 1.1 4.2 3 1 1 4 4 4 0 Tropomyosin like APG6 PF04111.7 EMC85137.1 - 3.1 6.7 10.7 1.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Autophagy protein Apg6 DUF948 PF06103.6 EMC85137.1 - 4.6 7.1 3.5 1.4e+02 2.3 0.1 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) UCH PF00443.24 EMC85138.1 - 1.6e-84 283.1 0.0 4.7e-84 281.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC85138.1 - 1.4e-26 93.6 0.0 2.5e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CS PF04969.11 EMC85138.1 - 1.8e-19 70.0 5.8 1.5e-11 44.6 0.1 2.7 3 0 0 3 3 3 2 CS domain zf-MYND PF01753.13 EMC85138.1 - 2e-08 33.9 14.9 2e-08 33.9 10.4 3.1 3 0 0 3 3 3 1 MYND finger SNF PF00209.13 EMC85139.1 - 1.5e-187 624.2 25.6 1.7e-187 624.0 17.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Crystall PF00030.14 EMC85140.1 - 5.4e-34 115.9 0.0 2.8e-19 68.7 0.0 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EMC85140.1 - 0.11 12.2 0.0 1.6 8.5 0.0 2.5 3 0 0 3 3 3 0 Beta/Gamma crystallin tRNA-synt_1c PF00749.16 EMC85141.1 - 2.8e-109 364.6 0.0 3.5e-109 364.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMC85141.1 - 9.7e-49 165.3 0.0 1.9e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EMC85141.1 - 7.1e-29 100.4 0.0 1.6e-28 99.2 0.0 1.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EMC85141.1 - 1.8e-27 95.8 2.0 3.1e-27 95.0 1.4 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF3504 PF12012.3 EMC85142.1 - 3e-64 215.9 0.8 3e-64 215.9 0.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) CARD PF00619.16 EMC85142.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.8 1 0 0 1 1 1 1 Caspase recruitment domain DUF498 PF04430.9 EMC85143.1 - 1.2e-23 82.7 0.0 1.3e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DALR_1 PF05746.10 EMC85144.1 - 4.8e-20 71.7 0.0 8.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain WD40 PF00400.27 EMC85145.1 - 4.5e-12 45.3 5.0 5.6 7.0 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat EF-hand_7 PF13499.1 EMC85146.1 - 2.8e-08 33.7 0.0 7.5e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair 2OG-FeII_Oxy_3 PF13640.1 EMC85146.1 - 1.4e-07 31.9 0.0 3.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_1 PF00036.27 EMC85146.1 - 3.2e-07 29.1 0.0 0.0095 15.1 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EMC85146.1 - 2.1e-06 26.7 0.1 0.025 13.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC85146.1 - 2.8e-06 26.7 1.3 0.017 14.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain 2OG-FeII_Oxy PF03171.15 EMC85146.1 - 3.7e-06 27.1 0.1 1.6e-05 25.1 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EF-hand_8 PF13833.1 EMC85146.1 - 3e-05 23.5 0.0 0.017 14.6 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair 2OG-FeII_Oxy_4 PF13661.1 EMC85146.1 - 0.027 14.1 0.9 0.099 12.2 0.6 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fz PF01392.17 EMC85147.1 - 1.5e-31 109.1 6.7 3.4e-31 108.0 4.7 1.6 1 0 0 1 1 1 1 Fz domain IBR PF01485.16 EMC85148.1 - 3.4e-22 78.0 43.0 2.2e-13 49.8 4.7 3.7 3 0 0 3 3 3 3 IBR domain zf-C3HC4 PF00097.20 EMC85148.1 - 0.001 18.6 6.2 0.001 18.6 4.3 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC85148.1 - 0.0018 18.2 9.0 0.0018 18.2 6.3 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC85148.1 - 0.0062 16.3 11.4 0.0062 16.3 7.9 4.0 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EMC85148.1 - 0.14 11.8 44.5 0.074 12.7 6.8 3.8 3 0 0 3 3 3 0 zinc-RING finger domain DUF2500 PF10694.4 EMC85148.1 - 0.75 9.8 3.2 0.47 10.4 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) cNMP_binding PF00027.24 EMC85149.1 - 5.1e-44 148.0 0.0 2.9e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF627 PF04781.7 EMC85149.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) DUF3783 PF12646.2 EMC85149.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) MaoC_dehydratas PF01575.14 EMC85150.1 - 1.5e-21 76.0 0.0 2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EMC85150.1 - 2.7e-07 30.4 0.0 6.5e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 EMC85150.1 - 0.00019 21.4 0.0 0.00067 19.7 0.0 2.0 1 1 1 2 2 2 1 Thioesterase superfamily Transket_pyr PF02779.19 EMC85151.1 - 7.9e-48 162.2 0.0 1.2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMC85151.1 - 1.7e-36 124.9 0.1 1e-35 122.3 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain BTB_2 PF02214.17 EMC85152.1 - 9.3e-22 77.0 0.0 2.3e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain ACOX PF01756.14 EMC85153.1 - 1.1e-62 210.7 2.9 3.6e-61 205.8 0.4 2.2 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMC85153.1 - 4.2e-29 101.3 0.1 9.5e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMC85153.1 - 1.6e-07 30.6 0.0 2.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMC85153.1 - 8.3e-07 29.2 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC85153.1 - 0.017 15.3 0.1 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain HTH_25 PF13413.1 EMC85153.1 - 0.12 12.0 0.1 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1151 PF06625.6 EMC85154.1 - 5.9e-45 151.9 17.6 7e-45 151.7 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) Ala_racemase_N PF01168.15 EMC85154.1 - 0.068 12.7 0.5 0.087 12.3 0.3 1.0 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain SDP_N PF12278.3 EMC85154.1 - 0.084 12.4 10.5 0.11 12.1 7.3 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Synaptobrevin PF00957.16 EMC85154.1 - 0.42 10.2 2.3 0.6 9.7 1.6 1.4 1 0 0 1 1 1 0 Synaptobrevin Whirly PF08536.6 EMC85156.1 - 0.0056 16.1 0.2 0.009 15.4 0.0 1.5 2 0 0 2 2 2 1 Whirly transcription factor DUF667 PF05018.8 EMC85157.1 - 4.6e-26 91.2 0.0 5.9e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) HIT PF01230.18 EMC85158.1 - 2.4e-10 40.8 0.0 2.6e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 HIT domain SRP9-21 PF05486.7 EMC85159.1 - 7e-12 44.9 0.0 7.9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) XhlA PF10779.4 EMC85159.1 - 0.062 13.2 0.6 0.075 12.9 0.4 1.1 1 0 0 1 1 1 0 Haemolysin XhlA DUF3128 PF11326.3 EMC85159.1 - 0.08 13.0 0.1 0.091 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) EHN PF06441.7 EMC85160.1 - 1.5e-34 118.2 0.2 2.4e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMC85160.1 - 1.8e-14 54.1 0.0 8.7e-14 51.9 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC85160.1 - 3.1e-10 40.0 0.0 1.7e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF221 PF02714.10 EMC85161.1 - 3.5e-87 292.3 25.4 3.5e-87 292.3 17.6 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC85161.1 - 1.1e-22 80.2 1.2 1.1e-22 80.2 0.8 4.4 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMC85161.1 - 3.7e-13 49.7 1.6 7e-13 48.9 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 EMC85161.1 - 0.011 15.2 0.0 0.53 9.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TGFb_propeptide PF00688.13 EMC85162.1 - 4.6e-28 98.1 0.4 9.1e-28 97.1 0.3 1.4 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC85162.1 - 8.2e-11 42.1 5.7 4.5e-08 33.3 0.9 2.4 1 1 1 2 2 2 2 Transforming growth factor beta like domain Telomere_Sde2 PF13019.1 EMC85164.1 - 1.9e-32 112.2 1.7 2.3e-32 111.9 1.2 1.1 1 0 0 1 1 1 1 Telomere stability and silencing Virul_Fac PF10139.4 EMC85164.1 - 0.0094 13.9 0.4 0.011 13.7 0.3 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor PVL_ORF50 PF07768.6 EMC85164.1 - 0.034 14.1 3.5 0.048 13.6 2.5 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family PcfJ PF14284.1 EMC85164.1 - 0.049 13.1 1.2 0.066 12.7 0.9 1.3 1 0 0 1 1 1 0 PcfJ-like protein ScpA_ScpB PF02616.9 EMC85164.1 - 0.079 12.5 1.2 0.095 12.2 0.8 1.1 1 0 0 1 1 1 0 ScpA/B protein Pox_A_type_inc PF04508.7 EMC85164.1 - 0.67 9.8 4.4 1.1 9.2 1.7 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Histone PF00125.19 EMC85165.1 - 1.7e-33 114.5 0.2 2e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC85165.1 - 6.2e-05 23.1 0.0 8.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EMC85165.1 - 0.013 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EMC85165.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GOLD_2 PF13897.1 EMC85166.1 - 6.6e-70 233.6 4.1 6.6e-70 233.6 2.9 3.1 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking ACBP PF00887.14 EMC85166.1 - 1.9e-16 59.4 0.0 6.6e-16 57.7 0.0 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1675 PF07897.6 EMC85166.1 - 0.0045 16.9 10.4 0.0045 16.9 7.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1675) PAT1 PF09770.4 EMC85166.1 - 0.016 13.4 20.4 0.022 13.0 14.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Merozoite_SPAM PF07133.6 EMC85166.1 - 1.3 8.9 29.3 1.1 9.1 11.8 2.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) U79_P34 PF03064.11 EMC85166.1 - 1.6 8.2 18.3 0.29 10.6 8.9 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Ycf1 PF05758.7 EMC85166.1 - 3.4 5.2 21.0 1.5 6.4 12.8 1.6 2 0 0 2 2 2 0 Ycf1 MAP7 PF05672.6 EMC85166.1 - 6.6 6.0 60.5 0.26 10.6 35.9 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DIRP PF06584.8 EMC85167.1 - 5.6e-42 142.0 0.1 1.4e-41 140.7 0.1 1.7 1 0 0 1 1 1 1 DIRP FTA4 PF13093.1 EMC85167.1 - 0.015 14.7 2.8 0.032 13.6 2.0 1.8 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PARP PF00644.15 EMC85168.1 - 3.7e-79 264.9 0.0 3.7e-79 264.9 0.0 2.5 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EMC85168.1 - 3.4e-39 133.5 2.4 3.4e-39 133.5 1.6 3.1 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase, regulatory domain PADR1 PF08063.7 EMC85168.1 - 2.2e-23 81.3 0.3 4e-23 80.5 0.2 1.4 1 0 0 1 1 1 1 PADR1 (NUC008) domain WGR PF05406.10 EMC85168.1 - 7.2e-21 73.9 1.5 1.2e-20 73.2 0.1 2.2 2 0 0 2 2 2 1 WGR domain BRCT PF00533.21 EMC85168.1 - 2.8e-09 37.0 0.2 1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.13 EMC85168.1 - 9.3e-09 35.4 4.8 1.5e-08 34.7 0.0 3.3 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region IPK PF03770.11 EMC85170.1 - 9.3e-45 152.6 0.0 2e-44 151.6 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase Retrotrans_gag PF03732.12 EMC85170.1 - 0.0074 16.3 0.8 0.38 10.8 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein Presenilin PF01080.12 EMC85171.1 - 8.9e-166 551.6 19.5 5.3e-119 397.6 8.8 2.1 1 1 1 2 2 2 2 Presenilin ABC1 PF03109.11 EMC85172.1 - 5.1e-34 116.8 0.0 1.1e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Oxidored_q1_N PF00662.15 EMC85172.1 - 0.14 11.7 0.2 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus CNH PF00780.17 EMC85173.1 - 1.1e-71 241.4 0.1 2.1e-71 240.5 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 EMC85173.1 - 3.7e-29 101.6 1.1 7.1e-29 100.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DMPK_coil PF08826.5 EMC85173.1 - 9.2e-26 89.5 11.6 9.2e-26 89.5 8.1 9.3 7 4 3 11 11 11 2 DMPK coiled coil domain like Pkinase_Tyr PF07714.12 EMC85173.1 - 1.2e-12 47.5 0.0 4e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EMC85173.1 - 2.9e-11 42.9 7.5 8.2e-11 41.4 5.2 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC85173.1 - 2.9e-06 27.6 2.3 1e-05 25.9 1.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain AAA_13 PF13166.1 EMC85173.1 - 0.0021 16.6 19.8 0.0021 16.6 13.8 3.2 1 1 2 3 3 3 1 AAA domain PBD PF00786.23 EMC85173.1 - 0.011 16.1 0.3 0.062 13.7 0.2 2.4 1 0 0 1 1 1 0 P21-Rho-binding domain Reo_sigmaC PF04582.7 EMC85173.1 - 0.98 8.5 20.4 1.1 8.4 0.2 3.9 2 2 2 4 4 4 0 Reovirus sigma C capsid protein OCC1 PF15506.1 EMC85174.1 - 3.1e-21 75.0 0.1 4.7e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 OCC1 family PID PF00640.18 EMC85175.1 - 3e-09 36.9 0.3 8.5e-09 35.5 0.2 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.24 EMC85175.1 - 1.9e-07 31.2 0.0 1.3e-06 28.5 0.0 2.5 3 0 0 3 3 3 1 PH domain PTB PF08416.8 EMC85175.1 - 8.8e-06 25.6 0.1 2.1e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain DUF3263 PF11662.3 EMC85175.1 - 0.006 16.0 0.3 0.03 13.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3263) PH_9 PF15410.1 EMC85175.1 - 0.0074 16.4 0.0 0.029 14.5 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Aldedh PF00171.17 EMC85176.1 - 4e-161 536.4 0.0 5.4e-161 536.0 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.14 EMC85176.1 - 1.5e-45 155.0 0.0 2.6e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EMC85176.1 - 7.7e-14 51.5 0.0 1.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.20 EMC85176.1 - 7.6e-06 26.1 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.6 EMC85176.1 - 0.0051 16.0 0.0 0.016 14.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF4598 PF15370.1 EMC85177.1 - 5.6e-12 45.9 1.7 7.8e-12 45.4 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Sigma70_r1_1 PF03979.9 EMC85177.1 - 0.0018 18.2 5.8 0.0029 17.5 4.1 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 Bd3614_N PF14442.1 EMC85177.1 - 0.0069 16.3 0.9 0.0086 16.0 0.6 1.1 1 0 0 1 1 1 1 Bd3614-like deaminase N-terminal CENP-B_dimeris PF09026.5 EMC85177.1 - 2.7 8.2 6.7 10 6.4 3.2 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MgtE PF01769.11 EMC85178.1 - 1.4e-42 145.1 15.1 4.2e-27 95.0 3.3 3.2 4 0 0 4 4 4 2 Divalent cation transporter MHC2-interact PF09307.5 EMC85178.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 CLIP, MHC2 interacting Sulfotransfer_2 PF03567.9 EMC85179.1 - 2.7e-69 233.6 7.1 3.2e-69 233.4 4.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF2115 PF09888.4 EMC85179.1 - 0.037 14.1 1.9 0.047 13.8 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TGFb_propeptide PF00688.13 EMC85181.1 - 4.1e-46 157.2 2.5 5.7e-46 156.7 1.7 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC85181.1 - 1.1e-41 141.3 0.8 2e-41 140.5 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain DUF908 PF06012.7 EMC85181.1 - 0.0063 15.8 0.2 0.0096 15.2 0.1 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Cpn60_TCP1 PF00118.19 EMC85182.1 - 6.5e-142 473.5 13.5 7.3e-142 473.3 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EMC85182.1 - 0.0091 15.4 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Phage Tail Protein X THP2 PF09432.5 EMC85182.1 - 0.14 11.9 0.6 0.47 10.3 0.2 2.0 2 0 0 2 2 2 0 Tho complex subunit THP2 UPF0564 PF10595.4 EMC85183.1 - 1.4e-74 251.2 54.3 5.1e-74 249.3 37.7 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0564 DHC PF09626.5 EMC85183.1 - 0.057 14.0 0.8 0.057 14.0 0.5 2.4 2 1 0 2 2 2 0 Dihaem cytochrome c Cadherin PF00028.12 EMC85184.1 - 8e-09 35.6 0.1 1.8e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Cadherin domain DcuA_DcuB PF03605.9 EMC85184.1 - 0.073 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Potass_KdpF PF09604.5 EMC85184.1 - 5.2 7.0 7.0 9.3 6.2 4.8 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Cadherin PF00028.12 EMC85186.1 - 6.9e-27 93.5 0.4 3.8e-18 65.5 0.0 2.6 2 1 0 2 2 2 2 Cadherin domain Cadherin PF00028.12 EMC85187.1 - 3.8e-122 398.8 15.2 1.7e-20 73.0 0.0 7.1 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.7 EMC85187.1 - 0.00036 20.0 1.3 2.7 7.6 0.0 4.5 6 0 0 6 6 6 2 Cadherin-like Big_3_4 PF13754.1 EMC85187.1 - 0.38 11.1 17.0 3 8.2 0.1 6.2 6 1 0 6 6 6 0 Bacterial Ig-like domain (group 3) DUF3342 PF11822.3 EMC85188.1 - 5e-106 354.4 13.6 6.5e-106 354.0 9.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Adenylsucc_synt PF00709.16 EMC85188.1 - 0.062 11.9 0.0 0.53 8.8 0.0 2.0 2 0 0 2 2 2 0 Adenylosuccinate synthetase TPD PF14811.1 EMC85189.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif TFIID_20kDa PF03847.8 EMC85189.1 - 0.24 11.7 2.9 51 4.2 0.0 3.8 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A RHD PF00554.17 EMC85190.1 - 2.6e-76 255.0 0.0 3.9e-76 254.4 0.0 1.3 1 0 0 1 1 1 1 Rel homology domain (RHD) zf-C2H2 PF00096.21 EMC85191.1 - 1.1e-24 85.2 56.9 1.7e-05 24.9 2.0 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC85191.1 - 8.4e-17 60.5 55.8 2e-07 30.9 0.9 8.9 9 0 0 9 9 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC85191.1 - 5.2e-11 42.0 53.2 0.017 15.4 0.3 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC85191.1 - 6.7e-09 35.3 15.1 1.8e-06 27.6 0.2 7.0 10 0 0 10 10 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC85191.1 - 0.002 18.2 2.8 0.002 18.2 1.9 5.5 6 0 0 6 6 5 2 C2H2-type zinc-finger domain BSP_II PF05432.6 EMC85191.1 - 0.013 14.8 11.0 0.024 13.9 7.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) GAGA PF09237.6 EMC85191.1 - 0.053 13.1 7.0 1.9 8.1 0.2 2.9 2 1 0 2 2 2 0 GAGA factor DUF4329 PF14220.1 EMC85191.1 - 0.066 13.1 2.8 0.081 12.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) Ribosomal_60s PF00428.14 EMC85191.1 - 0.095 13.1 10.5 0.21 12.0 7.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EMC85191.1 - 0.69 9.4 10.8 1.2 8.5 7.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EMC85191.1 - 1.2 7.5 14.4 1.7 7.0 10.0 1.2 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EMC85191.1 - 1.5 9.0 14.4 3.3 7.9 10.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2_jaz PF12171.3 EMC85191.1 - 2.8 8.1 44.8 0.52 10.5 1.4 6.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding NOA36 PF06524.7 EMC85191.1 - 6 6.0 19.5 0.19 10.9 4.8 2.3 2 0 0 2 2 2 0 NOA36 protein WD-3 PF09765.4 EMC85193.1 - 1e-106 356.4 0.4 1.3e-106 356.1 0.3 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.3 EMC85193.1 - 4e-30 103.5 3.0 7.5e-30 102.7 2.1 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EMC85193.1 - 4.9e-06 26.2 3.4 1.2e-05 24.9 2.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC85193.1 - 0.0011 19.0 0.5 0.0032 17.5 0.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC85193.1 - 0.19 11.5 2.1 0.64 9.8 1.5 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4626 PF15422.1 EMC85194.1 - 0.33 10.9 2.9 0.2 11.6 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4626) Pkinase PF00069.20 EMC85195.1 - 8e-19 67.7 0.0 1.8e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85195.1 - 8.3e-11 41.4 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Crust_neurohorm PF01147.12 EMC85195.1 - 0.005 16.1 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 Crustacean CHH/MIH/GIH neurohormone family Pentapeptide_2 PF01469.13 EMC85197.1 - 3.5e-05 23.3 22.2 0.93 9.1 0.4 5.5 1 1 7 8 8 8 8 Pentapeptide repeats (8 copies) PMG PF05287.7 EMC85197.1 - 0.0002 21.2 0.8 3.2 7.5 0.0 3.2 1 1 3 4 4 4 4 PMG protein Pentapeptide_2 PF01469.13 EMC85198.1 - 3.5e-05 23.3 22.2 0.93 9.1 0.4 5.5 1 1 7 8 8 8 8 Pentapeptide repeats (8 copies) PMG PF05287.7 EMC85198.1 - 0.0002 21.2 0.8 3.2 7.5 0.0 3.2 1 1 3 4 4 4 4 PMG protein TF_AP-2 PF03299.9 EMC85199.1 - 3.1e-98 327.4 0.0 8.6e-98 325.9 0.0 1.6 2 0 0 2 2 2 1 Transcription factor AP-2 TF_AP-2 PF03299.9 EMC85200.1 - 4.8e-92 307.2 0.0 6.9e-92 306.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 CAP PF00188.21 EMC85201.1 - 2.6e-22 79.6 2.4 3.7e-22 79.1 1.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.5 EMC85201.1 - 4e-21 75.0 13.8 4e-21 75.0 9.5 1.8 2 0 0 2 2 2 1 Crisp p450 PF00067.17 EMC85202.1 - 3.6e-142 474.1 0.0 4.3e-142 473.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC85203.1 - 1.1e-134 449.5 0.1 1.2e-134 449.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPP_enzyme_M PF00205.17 EMC85203.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain CENP-Q PF13094.1 EMC85204.1 - 1.4e-16 60.9 16.7 1.4e-16 60.9 11.6 1.4 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.6 EMC85204.1 - 0.00069 18.2 5.8 0.00069 18.2 4.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Tropomyosin PF00261.15 EMC85204.1 - 0.0013 17.8 11.6 0.0013 17.8 8.1 2.1 2 0 0 2 2 2 1 Tropomyosin V_ATPase_I PF01496.14 EMC85204.1 - 0.052 11.4 8.8 0.063 11.1 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2514 PF10721.4 EMC85204.1 - 0.078 12.6 1.3 0.13 11.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Interfer-bind PF09294.5 EMC85204.1 - 0.13 12.2 1.8 0.18 11.8 0.3 1.9 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Tropomyosin_1 PF12718.2 EMC85204.1 - 0.7 9.7 20.6 0.19 11.5 11.8 2.0 2 1 0 2 2 2 0 Tropomyosin like DivIC PF04977.10 EMC85204.1 - 0.97 8.9 14.2 0.14 11.6 6.3 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF489 PF04356.7 EMC85204.1 - 1.2 8.7 9.6 1.1 8.8 4.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF793 PF05633.6 EMC85204.1 - 3.2 6.4 9.1 1 8.0 3.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF793) DUF1664 PF07889.7 EMC85204.1 - 3.9 7.2 15.5 0.49 10.2 5.2 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 EMC85204.1 - 7.5 6.2 13.9 2.1 8.0 5.6 2.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 COG5 PF10392.4 EMC85204.1 - 9.3 6.2 13.6 1.5 8.7 3.0 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 MM_CoA_mutase PF01642.17 EMC85205.1 - 8.2e-254 842.4 0.0 9.7e-254 842.2 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 EMC85205.1 - 1.5e-13 50.6 0.3 4.5e-13 49.1 0.2 1.9 1 0 0 1 1 1 1 B12 binding domain 3-alpha PF03475.9 EMC85205.1 - 0.073 12.8 0.6 0.25 11.0 0.4 1.9 1 0 0 1 1 1 0 3-alpha domain 7tm_1 PF00001.16 EMC85206.1 - 3.8e-35 121.2 14.3 4.8e-35 120.9 9.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC85206.1 - 2.5e-06 26.8 11.3 4.1e-06 26.1 7.9 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF1230 PF06799.6 EMC85206.1 - 0.22 11.3 6.0 0.84 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) Brevenin PF03032.10 EMC85207.1 - 0.079 12.8 0.4 0.079 12.8 0.3 2.1 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family DUF4028 PF13220.1 EMC85207.1 - 0.093 12.3 0.4 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) Filament PF00038.16 EMC85208.1 - 6.4e-101 337.9 39.4 7.5e-101 337.7 27.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC85208.1 - 5.5e-07 29.3 35.1 0.00063 19.4 0.6 3.5 3 1 0 3 3 3 3 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EMC85208.1 - 0.00025 20.9 30.9 0.025 14.4 4.1 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 EMC85208.1 - 0.0043 16.8 13.3 1 9.2 0.7 4.0 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 EMC85208.1 - 0.0047 14.7 36.1 0.013 13.3 21.2 2.7 1 1 0 2 2 2 1 Myosin tail Reo_sigmaC PF04582.7 EMC85208.1 - 0.012 14.8 2.3 3.5 6.6 0.4 2.9 1 1 3 4 4 4 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EMC85208.1 - 0.016 15.1 1.0 0.016 15.1 0.7 5.2 4 2 1 5 5 5 0 bZIP transcription factor DUF883 PF05957.8 EMC85208.1 - 0.022 15.1 19.4 0.98 9.8 4.9 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.6 EMC85208.1 - 0.025 14.4 2.1 0.025 14.4 1.4 5.6 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EMC85208.1 - 0.026 14.6 1.3 0.026 14.6 0.9 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EMC85208.1 - 0.042 13.4 38.3 0.022 14.3 4.5 3.2 2 1 1 3 3 3 0 IncA protein HALZ PF02183.13 EMC85208.1 - 0.05 13.3 0.7 0.05 13.3 0.5 4.5 4 1 1 5 5 3 0 Homeobox associated leucine zipper AAA_13 PF13166.1 EMC85208.1 - 0.077 11.4 26.7 0.79 8.1 18.6 2.3 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 EMC85208.1 - 0.12 12.2 37.7 0.19 11.5 10.7 3.8 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EMC85208.1 - 0.14 12.0 35.0 0.05 13.5 9.0 3.4 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 EMC85208.1 - 0.22 9.8 7.6 0.13 10.7 3.5 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 EMC85208.1 - 0.26 11.1 40.1 0.051 13.4 12.2 3.3 1 1 1 3 3 3 0 Tropomyosin like CHDCT2 PF08074.6 EMC85208.1 - 0.43 10.3 10.3 0.6 9.8 0.1 3.0 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DASH_Dam1 PF08653.5 EMC85208.1 - 0.43 10.3 1.5 48 3.8 0.0 3.7 4 0 0 4 4 3 0 DASH complex subunit Dam1 DUF972 PF06156.8 EMC85208.1 - 0.5 10.7 37.8 1.9 8.9 7.4 5.0 2 2 3 5 5 5 0 Protein of unknown function (DUF972) BicD PF09730.4 EMC85208.1 - 0.52 8.6 31.5 1.1 7.5 4.5 2.2 1 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Spc7 PF08317.6 EMC85208.1 - 0.52 8.9 35.6 0.026 13.2 7.0 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein TMCO5 PF14992.1 EMC85208.1 - 1.5 7.9 31.8 0.29 10.2 9.5 2.2 1 1 1 2 2 2 0 TMCO5 family DUF342 PF03961.8 EMC85208.1 - 2.2 6.6 31.5 0.39 9.0 3.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 EMC85208.1 - 2.2 8.2 36.2 0.33 10.9 3.7 3.6 2 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit HOOK PF05622.7 EMC85208.1 - 2.7 5.7 34.9 1.3 6.7 5.6 2.1 1 1 0 2 2 2 0 HOOK protein Lectin_N PF03954.9 EMC85208.1 - 5.5 6.4 9.6 3.7 6.9 1.5 3.1 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain OsmC PF02566.14 EMC85208.1 - 6 7.1 6.6 8.8 6.5 0.1 3.1 2 1 1 3 3 3 0 OsmC-like protein DivIVA PF05103.8 EMC85208.1 - 8.5 6.4 33.2 0.092 12.8 6.8 4.1 3 1 0 4 4 4 0 DivIVA protein Collagen PF01391.13 EMC85209.1 - 0.91 9.1 23.4 0.71 9.4 4.5 2.4 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Collagen PF01391.13 EMC85211.1 - 5.5e-21 73.8 47.6 1.5e+04 -4.6 33.0 5.9 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Cornifin PF02389.10 EMC85212.1 - 8.3e-08 32.2 34.5 1.4e-07 31.5 23.9 1.4 1 1 0 1 1 1 1 Cornifin (SPRR) family PHTB1_C PF14728.1 EMC85213.1 - 3.8e-133 443.9 1.2 6.1e-133 443.2 0.4 1.6 2 0 0 2 2 2 1 PTHB1 C-terminus PHTB1_N PF14727.1 EMC85213.1 - 5.2e-102 341.9 0.0 6.6e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus 7tm_1 PF00001.16 EMC85214.1 - 5.1e-44 150.3 13.6 7.1e-44 149.8 9.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MRAP PF15183.1 EMC85214.1 - 1.5 8.4 8.1 0.5 10.0 0.5 2.7 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Dpy19 PF10034.4 EMC85215.1 - 3.2e-249 828.4 21.5 3.7e-249 828.2 14.9 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation T-box PF00907.17 EMC85216.1 - 1.8e-74 249.2 0.0 2.4e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 T-box ubiquitin PF00240.18 EMC85217.1 - 1.2e-06 27.8 0.1 1.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EMC85217.1 - 4e-05 23.7 0.0 6.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMC85217.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Golgin_A5 PF09787.4 EMC85217.1 - 0.57 8.6 4.3 0.86 8.0 3.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Septin PF00735.13 EMC85218.1 - 1.5e-123 411.3 0.1 1.5e-123 411.3 0.1 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMC85218.1 - 1.3e-07 31.5 0.0 6.3e-07 29.3 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC85218.1 - 2.5e-05 23.5 0.3 0.00012 21.3 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMC85218.1 - 0.00086 18.4 0.0 0.00086 18.4 0.0 2.6 3 0 0 3 3 3 1 AIG1 family AAA_22 PF13401.1 EMC85218.1 - 0.0039 17.3 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMC85218.1 - 0.009 15.4 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain Ras PF00071.17 EMC85218.1 - 0.016 14.5 2.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.13 EMC85218.1 - 0.021 14.1 0.0 0.06 12.6 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 EMC85218.1 - 0.021 15.1 0.0 0.021 15.1 0.0 2.7 3 1 0 3 3 2 0 ABC transporter Miro PF08477.8 EMC85218.1 - 0.027 14.9 0.0 0.027 14.9 0.0 2.8 3 1 0 3 3 3 0 Miro-like protein AAA_16 PF13191.1 EMC85218.1 - 0.028 14.4 0.5 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EMC85218.1 - 0.036 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EMC85218.1 - 0.038 13.1 0.0 0.038 13.1 0.0 2.9 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region MobB PF03205.9 EMC85218.1 - 0.043 13.5 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMC85218.1 - 0.16 11.7 10.1 15 5.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EMC85218.1 - 0.28 10.6 0.0 0.28 10.6 0.0 2.4 2 1 0 2 2 1 0 FtsK/SpoIIIE family DUF2937 PF11157.3 EMC85218.1 - 3.1 7.1 7.9 3.9 6.7 4.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Snf7 PF03357.16 EMC85219.1 - 4e-37 127.2 29.6 4.5e-37 127.0 20.5 1.0 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 EMC85219.1 - 1.1 9.2 17.3 1.3 9.0 6.1 2.1 1 1 1 2 2 2 0 YlqD protein DUF342 PF03961.8 EMC85219.1 - 2.2 6.6 10.6 2.5 6.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pox_A_type_inc PF04508.7 EMC85219.1 - 2.3 8.2 5.8 17 5.5 1.7 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fibrinogen_C PF00147.13 EMC85221.1 - 8.2e-68 228.5 5.3 1.3e-67 227.8 3.7 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4463 PF14703.1 EMC85221.1 - 0.058 13.9 3.5 5.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) YscO PF07321.7 EMC85221.1 - 0.3 10.8 27.8 0.09 12.5 3.0 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO V_ATPase_I PF01496.14 EMC85221.1 - 0.95 7.2 20.2 1.3 6.7 14.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZYG-11_interact PF05884.7 EMC85221.1 - 3.6 6.6 5.4 1.9 7.5 2.3 1.5 1 1 0 1 1 1 0 Interactor of ZYG-11 Cache_2 PF08269.6 EMC85221.1 - 4.5 7.3 9.2 3.3 7.7 0.7 2.7 2 0 0 2 2 2 0 Cache domain Toprim PF01751.17 EMC85222.1 - 0.024 14.5 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Toprim domain ITI_HC_C PF06668.7 EMC85223.1 - 4.2e-75 251.3 0.1 7.8e-75 250.4 0.1 1.5 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.5 EMC85223.1 - 1.6e-46 156.8 4.5 3e-46 155.9 3.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EMC85223.1 - 1e-19 70.9 0.1 2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC85223.1 - 1.5e-15 57.7 0.2 2.9e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC85223.1 - 2.1e-14 53.4 0.0 3.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EMC85223.1 - 1.6e-06 28.1 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 EMC85223.1 - 0.0036 16.4 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT PF08487.5 EMC85224.1 - 8.8e-46 154.4 1.1 2.7e-45 152.8 0.8 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EMC85224.1 - 5.1e-24 84.9 0.1 8.4e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC85224.1 - 2.1e-20 73.0 0.0 3.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC85224.1 - 6.2e-20 72.0 0.1 1e-19 71.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMC85224.1 - 1.2e-07 31.1 0.0 2.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 EMC85224.1 - 7e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2201 PF09967.4 EMC85224.1 - 6.2e-05 23.0 0.1 0.00014 21.8 0.1 1.6 1 0 0 1 1 1 1 VWA-like domain (DUF2201) Ribosomal_TL5_C PF14693.1 EMC85224.1 - 0.026 14.7 0.2 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein TL5, C-terminal domain Spectrin PF00435.16 EMC85224.1 - 0.071 13.4 2.9 0.25 11.6 0.4 2.4 2 0 0 2 2 2 0 Spectrin repeat CobT_C PF11775.3 EMC85224.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Fer4_13 PF13370.1 EMC85225.1 - 0.071 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF3661 PF12400.3 EMC85226.1 - 6.1e-10 39.2 0.4 1.1e-09 38.4 0.1 1.5 2 0 0 2 2 2 1 Vaculolar membrane protein MBT PF02820.13 EMC85227.1 - 1.7e-87 287.3 0.3 8.1e-25 86.5 0.0 4.4 4 0 0 4 4 4 4 mbt repeat DUF3588 PF12140.3 EMC85227.1 - 1.7e-42 144.2 0.1 4.3e-42 142.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 EMC85227.1 - 9.3e-10 38.5 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC85227.1 - 8.8e-07 28.6 0.0 2.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC85227.1 - 0.00054 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 EMC85227.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Anophelin PF10731.4 EMC85227.1 - 3.9 7.6 6.3 8.8 6.5 4.4 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Rft-1 PF04506.8 EMC85228.1 - 9.9e-84 281.6 18.5 1.3e-83 281.2 12.8 1.0 1 0 0 1 1 1 1 Rft protein Phtf-FEM1B_bdg PF12129.3 EMC85228.1 - 0.76 9.1 7.2 0.35 10.1 3.2 1.8 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Pkinase PF00069.20 EMC85229.1 - 3.5e-63 213.1 0.0 4.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85229.1 - 1.5e-31 109.4 0.0 2.4e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 EMC85229.1 - 3.5e-08 33.9 11.1 3.5e-08 33.9 7.7 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 EMC85229.1 - 0.04 13.6 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ORC4_C PF14629.1 EMC85230.1 - 5.7e-52 176.0 2.9 9.5e-52 175.3 2.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EMC85230.1 - 1.5e-13 51.1 7.1 4.5e-13 49.5 1.8 2.9 2 2 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EMC85230.1 - 2.1e-10 40.7 0.3 4.9e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EMC85230.1 - 1.5e-09 38.0 0.8 3.7e-09 36.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMC85230.1 - 1.2e-08 35.2 0.4 2.9e-08 34.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMC85230.1 - 4.7e-07 29.6 4.9 9.6e-07 28.5 1.6 2.6 2 1 0 2 2 1 1 NACHT domain AAA_14 PF13173.1 EMC85230.1 - 0.00018 21.3 0.3 0.0007 19.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMC85230.1 - 0.00052 19.0 0.2 0.00087 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 EMC85230.1 - 0.00077 19.5 2.2 0.01 15.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 EMC85230.1 - 0.0039 16.4 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EMC85230.1 - 0.0048 15.8 0.1 0.008 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DAP3 PF10236.4 EMC85230.1 - 0.0055 15.6 2.0 0.17 10.7 0.1 2.4 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EMC85230.1 - 0.01 14.8 0.3 0.018 14.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EMC85230.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EMC85230.1 - 0.017 15.5 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 EMC85230.1 - 0.025 14.4 0.0 0.087 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMC85230.1 - 0.035 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 EMC85230.1 - 0.047 12.3 0.1 0.11 11.0 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF3399 PF11879.3 EMC85230.1 - 0.047 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) AAA_17 PF13207.1 EMC85230.1 - 0.057 14.2 0.0 0.39 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMC85230.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMC85230.1 - 0.071 12.5 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EMC85230.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EMC85230.1 - 0.23 11.7 1.1 0.6 10.3 0.7 2.0 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EMC85230.1 - 6.8 6.9 7.2 2.3e+02 1.9 5.0 2.7 1 1 0 1 1 1 0 AAA domain PWWP PF00855.12 EMC85231.1 - 4.7e-05 23.5 0.3 0.00045 20.3 0.2 2.3 1 1 0 1 1 1 1 PWWP domain MBD PF01429.14 EMC85231.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyl-CpG binding domain Kinesin PF00225.18 EMC85232.1 - 1.2e-110 369.4 0.3 1.2e-110 369.4 0.2 2.4 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EMC85232.1 - 1.5 7.9 25.8 0.033 13.3 2.2 4.2 1 1 2 4 4 4 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 EMC85232.1 - 6.2 6.6 11.0 21 4.9 0.5 4.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF1858 PF08984.6 EMC85234.1 - 0.17 11.5 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) UPAR_LY6 PF00021.16 EMC85234.1 - 0.23 11.8 14.6 0.38 11.1 10.1 1.4 1 0 0 1 1 1 0 u-PAR/Ly-6 domain DUF2246 PF10229.4 EMC85235.1 - 1e-126 421.9 0.0 1.2e-126 421.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) DUF4085 PF13315.1 EMC85235.1 - 0.044 13.1 0.3 0.061 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Ras PF00071.17 EMC85236.1 - 7.4e-43 145.7 0.0 9.9e-43 145.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC85236.1 - 1.5e-16 60.9 0.0 2.6e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC85236.1 - 6.8e-07 28.6 0.0 1e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC85236.1 - 0.016 14.4 0.0 0.046 12.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EMC85236.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 EMC85236.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EMC85236.1 - 0.037 13.9 0.0 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMC85236.1 - 0.037 13.5 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L32p PF01783.18 EMC85236.1 - 0.054 13.6 0.5 1.8 8.8 0.2 3.0 2 1 0 2 2 2 0 Ribosomal L32p protein family AAA_16 PF13191.1 EMC85236.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NID PF07292.8 EMC85237.1 - 8.4e-10 38.5 0.1 0.00039 20.3 0.0 2.6 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_1 PF00076.17 EMC85237.1 - 9.6e-05 21.9 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC85237.1 - 0.00057 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 EMC85238.1 - 1.1e-38 131.2 0.0 8.5e-28 96.2 0.0 2.1 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_6 PF14259.1 EMC85238.1 - 5.8e-07 29.3 0.0 0.039 13.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85238.1 - 0.00041 20.1 0.3 0.49 10.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF237 PF03072.9 EMC85238.1 - 0.0045 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 MG032/MG096/MG288 family 1 RRM_1 PF00076.17 EMC85238.1 - 0.067 12.8 0.4 7.8 6.2 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CUB PF00431.15 EMC85239.1 - 2.3e-36 124.2 0.1 3.9e-36 123.4 0.1 1.4 1 0 0 1 1 1 1 CUB domain Xlink PF00193.12 EMC85239.1 - 1.6e-32 111.3 1.5 3.2e-32 110.4 1.0 1.5 1 0 0 1 1 1 1 Extracellular link domain Rif1_N PF12231.3 EMC85240.1 - 4e-84 282.7 7.1 4e-84 282.7 4.9 1.7 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Arf PF00025.16 EMC85241.1 - 8.7e-65 217.2 0.8 1e-64 216.9 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC85241.1 - 3.3e-14 52.5 0.4 3.6e-14 52.4 0.3 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC85241.1 - 2e-12 46.6 0.3 2.4e-12 46.4 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC85241.1 - 3.9e-11 43.4 0.1 5.2e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EMC85241.1 - 2.1e-08 33.3 0.9 1.3e-05 24.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EMC85241.1 - 1.2e-07 31.6 0.2 1.6e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC85241.1 - 2.1e-07 30.3 0.4 2.5e-07 30.0 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC85241.1 - 0.00014 21.3 0.3 0.0013 18.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EMC85241.1 - 0.0055 16.5 0.2 0.03 14.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain Octopine_DH PF02317.12 EMC85241.1 - 0.062 12.9 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain FeoB_N PF02421.13 EMC85241.1 - 0.067 12.4 1.0 0.32 10.2 0.7 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Guanylate_kin PF00625.16 EMC85242.1 - 3.3e-47 160.2 0.1 5.8e-47 159.5 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.3 EMC85242.1 - 7.3e-25 86.5 7.2 1.7e-24 85.4 5.0 1.7 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.23 EMC85242.1 - 0.00025 20.3 0.0 0.00096 18.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC85242.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC85242.1 - 0.02 14.3 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain VHS PF00790.14 EMC85243.1 - 3.5e-39 133.6 1.6 3e-38 130.6 0.1 2.4 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 EMC85243.1 - 8.5e-19 66.6 0.1 1.6e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC85243.1 - 8.7e-14 50.8 0.1 1.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC85243.1 - 1e-11 44.1 0.0 1.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EMC85243.1 - 4e-05 22.8 0.8 0.0001 21.5 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif ZapA PF05164.8 EMC85243.1 - 0.018 14.9 0.0 0.087 12.7 0.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapA FH2 PF02181.18 EMC85244.1 - 4.3e-104 348.3 12.3 4.3e-104 348.3 8.5 3.6 5 0 0 5 5 5 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EMC85244.1 - 7.9e-52 175.5 16.1 7.9e-52 175.5 11.2 2.8 2 1 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EMC85244.1 - 5.5e-23 81.2 21.3 2.9e-13 49.6 0.4 5.3 4 1 1 5 5 5 2 Diaphanous GTPase-binding Domain Reo_sigmaC PF04582.7 EMC85244.1 - 1.6 7.8 4.6 0.35 9.9 0.7 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Endonuc_Holl PF10107.4 EMC85244.1 - 2.7 7.6 15.8 0.46 10.1 2.3 2.9 2 1 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF1664 PF07889.7 EMC85244.1 - 4.4 7.1 17.6 0.63 9.8 7.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 EMC85244.1 - 9.9 6.0 19.7 0.014 15.2 4.8 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PT PF04886.7 EMC85245.1 - 0.00014 21.0 0.7 2.9 7.3 0.0 3.5 3 1 0 3 3 3 3 PT repeat FF PF01846.14 EMC85246.1 - 6.5e-46 154.0 25.1 1.4e-15 56.9 0.4 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.21 EMC85246.1 - 1.2e-18 66.6 19.1 1.4e-09 37.5 5.7 2.6 2 0 0 2 2 2 2 WW domain TPR_6 PF13174.1 EMC85246.1 - 7.3 7.2 7.5 15 6.3 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat IRK PF01007.15 EMC85247.1 - 8.8e-59 198.9 0.0 1.1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel DAO PF01266.19 EMC85249.1 - 4.5e-50 170.5 0.0 6.5e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 EMC85249.1 - 8.8e-12 44.9 0.4 2.3e-11 43.6 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC85249.1 - 2.2e-10 39.0 0.4 9.8e-05 21.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC85249.1 - 1.6e-09 36.7 0.2 8.5e-05 22.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain FAD_binding_2 PF00890.19 EMC85249.1 - 1e-08 34.5 0.2 4.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EMC85249.1 - 1.1e-08 34.6 0.4 8.6e-08 31.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EMC85249.1 - 2e-06 26.9 0.0 0.00051 19.0 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMC85249.1 - 7.3e-06 26.0 0.1 0.00041 20.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 EMC85249.1 - 3e-05 23.5 0.3 0.00012 21.5 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.1 EMC85249.1 - 0.00015 21.6 0.0 0.00047 20.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EMC85249.1 - 0.00037 19.7 0.4 0.97 8.9 0.0 2.5 2 0 0 2 2 2 2 EF hand HI0933_like PF03486.9 EMC85249.1 - 0.004 15.6 0.1 0.0062 15.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EMC85249.1 - 0.0073 16.3 0.4 0.033 14.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMC85249.1 - 0.011 16.1 0.1 0.043 14.2 0.1 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC85249.1 - 0.031 13.3 0.1 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EMC85249.1 - 0.043 12.8 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Gly_acyl_tr_N PF06021.6 EMC85249.1 - 0.087 12.2 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Lycopene_cycl PF05834.7 EMC85249.1 - 0.11 11.4 0.4 2.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein CENP-R PF06729.7 EMC85250.1 - 6.2 6.4 6.1 7.1 6.3 0.1 2.8 2 1 1 3 3 3 0 Kinetochore component, CENP-R PDZ PF00595.19 EMC85251.1 - 7e-10 38.9 0.0 1.6e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC85251.1 - 0.0054 16.6 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.20 EMC85252.1 - 7.2e-63 212.1 0.0 9.1e-63 211.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85252.1 - 3.5e-37 127.8 0.0 5e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 EMC85252.1 - 2.9e-15 55.2 0.2 6.5e-15 54.1 0.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.18 EMC85252.1 - 0.0012 18.6 0.0 0.015 15.0 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family TILa PF12714.2 EMC85253.1 - 0.033 13.9 3.2 35 4.2 0.0 4.3 3 2 2 5 5 5 0 TILa domain Keratin_B2_2 PF13885.1 EMC85255.1 - 2.3e-10 40.0 100.1 0.012 15.3 12.7 5.9 1 1 3 4 4 4 2 Keratin, high sulfur B2 protein Arm PF00514.18 EMC85256.1 - 7e-40 133.5 14.8 1.1e-09 37.7 0.0 9.2 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC85256.1 - 1.3e-08 34.9 0.5 0.0011 19.2 0.0 3.1 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 EMC85256.1 - 1.1e-05 25.1 4.8 0.92 9.7 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EMC85256.1 - 0.03 14.8 2.3 9.2 6.8 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat DAP PF15228.1 EMC85257.1 - 8.2e-11 42.4 2.6 1.2e-10 41.9 1.8 1.3 1 1 0 1 1 1 1 Death-associated protein DUF2633 PF11119.3 EMC85259.1 - 0.1 12.3 3.5 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Ank_2 PF12796.2 EMC85260.1 - 4.2e-60 200.0 9.9 6.6e-15 55.2 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMC85260.1 - 2.5e-54 178.4 15.1 5.5e-07 29.0 0.0 11.5 10 1 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EMC85260.1 - 4.6e-43 144.8 7.7 1e-09 38.6 0.0 7.4 3 2 5 8 8 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC85260.1 - 4.2e-37 125.3 7.9 2.4e-10 40.3 0.0 8.0 3 2 6 9 9 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC85260.1 - 1.3e-35 117.8 4.6 0.00017 21.4 0.0 10.4 11 0 0 11 11 10 6 Ankyrin repeat TPR_11 PF13414.1 EMC85260.1 - 4.6e-11 42.1 8.1 1.3e-06 27.9 1.9 2.7 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EMC85260.1 - 2.6e-07 30.0 7.9 0.36 10.8 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMC85260.1 - 6.4e-05 22.7 1.7 0.011 15.5 0.7 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC85260.1 - 0.00043 20.8 8.1 0.033 14.8 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC85260.1 - 0.0014 18.8 6.2 0.38 11.1 0.7 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC85260.1 - 0.0033 16.9 7.4 3.7 7.3 0.9 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 EMC85260.1 - 0.004 17.1 2.2 0.017 15.1 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.1 EMC85260.1 - 0.0059 16.2 0.7 0.26 11.1 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC85260.1 - 0.016 15.3 3.1 0.99 9.7 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC85260.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3898 PF13037.1 EMC85260.1 - 0.23 11.3 0.0 28 4.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3898) TPR_14 PF13428.1 EMC85260.1 - 1.3 9.8 12.1 0.076 13.6 1.9 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat WD40 PF00400.27 EMC85261.1 - 1.7e-62 205.1 24.1 2.2e-11 43.1 1.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.10 EMC85261.1 - 5e-23 80.8 0.1 9.6e-23 79.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.12 EMC85261.1 - 4.1e-14 52.1 0.2 7.1e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC85261.1 - 6.2e-12 45.5 0.2 1.4e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC85261.1 - 1.2e-05 24.9 0.0 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain eIF2A PF08662.6 EMC85261.1 - 0.00013 21.6 0.0 0.17 11.5 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EMC85261.1 - 0.00023 19.5 0.0 0.26 9.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EMC85261.1 - 0.0015 17.9 0.0 0.0045 16.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF2415 PF10313.4 EMC85261.1 - 0.52 10.0 2.4 28 4.4 0.0 3.9 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Collagen PF01391.13 EMC85263.1 - 5.4e-15 54.6 84.8 3.3e-09 36.1 26.1 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Glutenin_hmw PF03157.8 EMC85263.1 - 0.0013 17.1 66.2 0.0018 16.6 45.9 1.1 1 0 0 1 1 1 1 High molecular weight glutenin subunit CENP-T PF15511.1 EMC85263.1 - 0.89 8.7 11.6 1.1 8.3 8.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RINGv PF12906.2 EMC85264.1 - 7.3e-15 54.7 8.1 1.5e-14 53.7 5.6 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EMC85264.1 - 0.00025 20.9 4.2 0.00025 20.9 2.9 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EMC85264.1 - 0.0013 18.4 4.9 0.0028 17.4 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain DUF1139 PF06599.6 EMC85264.1 - 0.18 10.9 0.1 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) COesterase PF00135.23 EMC85266.1 - 1.6e-15 56.8 0.0 1.7e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family TTL PF03133.10 EMC85268.1 - 8e-80 267.8 0.3 8e-80 267.8 0.2 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMC85268.1 - 9.1e-07 27.9 0.1 0.0041 15.9 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EMC85268.1 - 0.00025 20.8 0.0 0.00053 19.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMC85268.1 - 0.00082 19.2 0.0 0.004 17.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC85268.1 - 0.0055 15.4 0.0 0.027 13.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.1 EMC85268.1 - 0.016 14.2 0.2 0.58 9.1 0.0 2.8 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp RimK PF08443.6 EMC85268.1 - 0.023 14.1 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Pkinase PF00069.20 EMC85269.1 - 7.9e-70 234.9 0.0 9.9e-70 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85269.1 - 1.4e-34 119.4 0.0 1.9e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC85269.1 - 3.7e-09 35.9 0.0 1.2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EMC85269.1 - 0.028 14.1 0.2 0.81 9.3 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family SAM_1 PF00536.25 EMC85270.1 - 1.4e-09 37.9 0.0 1.8e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC85270.1 - 5e-05 23.0 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC85270.1 - 7.1e-05 22.4 0.0 8.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Uricase PF01014.13 EMC85271.1 - 1.8e-55 186.7 0.0 4.4e-30 104.5 0.0 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.13 EMC85271.1 - 0.097 12.8 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Dihydroneopterin aldolase DNase_II PF03265.10 EMC85272.1 - 3.7e-109 364.6 1.1 4.5e-109 364.3 0.8 1.1 1 0 0 1 1 1 1 Deoxyribonuclease II Brix PF04427.13 EMC85273.1 - 1.3e-44 152.1 1.2 1.5e-44 151.9 0.8 1.1 1 0 0 1 1 1 1 Brix domain G-gamma PF00631.17 EMC85274.1 - 2.9e-09 36.5 0.0 3.1e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain YxiJ PF14176.1 EMC85275.1 - 4.3 7.4 11.1 0.12 12.5 0.5 2.8 3 0 0 3 3 3 0 YxiJ-like protein Glyco_hydro_18 PF00704.23 EMC85276.1 - 3e-41 142.0 0.1 3.9e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 7tm_1 PF00001.16 EMC85277.1 - 1e-35 123.1 24.7 1.6e-35 122.5 17.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM192 PF14802.1 EMC85277.1 - 0.2 10.4 3.5 0.4 9.4 2.4 1.4 1 0 0 1 1 1 0 TMEM192 family PKD_channel PF08016.7 EMC85278.1 - 1.3e-10 40.2 9.7 2.2e-10 39.5 6.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF4522 PF15022.1 EMC85278.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4522) ATG27 PF09451.5 EMC85278.1 - 0.018 14.2 0.2 0.043 13.0 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 Ion_trans PF00520.26 EMC85278.1 - 3.6 6.7 23.1 15 4.7 16.0 2.1 1 1 0 1 1 1 0 Ion transport protein PKD_channel PF08016.7 EMC85279.1 - 5.8e-11 41.4 13.4 1.2e-10 40.4 9.3 1.5 1 0 0 1 1 1 1 Polycystin cation channel WD40 PF00400.27 EMC85280.1 - 1.6e-08 34.0 13.0 0.014 15.2 0.4 5.5 4 2 0 4 4 4 4 WD domain, G-beta repeat CARD PF00619.16 EMC85281.1 - 7.1e-16 57.8 0.3 1.1e-15 57.1 0.2 1.3 1 0 0 1 1 1 1 Caspase recruitment domain Amidinotransf PF02274.12 EMC85282.1 - 1.6e-21 76.6 0.0 1.9e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase Cys_knot PF00007.17 EMC85283.1 - 7.4e-16 58.1 12.6 7.4e-16 58.1 8.7 3.2 3 1 0 3 3 3 1 Cystine-knot domain VWC PF00093.13 EMC85283.1 - 3.5e-10 39.8 12.8 3.5e-10 39.8 8.9 5.0 3 1 0 3 3 3 1 von Willebrand factor type C domain TSP_1 PF00090.14 EMC85283.1 - 1.3e-09 38.0 7.9 1.3e-09 38.0 5.5 3.8 4 0 0 4 4 4 1 Thrombospondin type 1 domain zf-HIT PF04438.11 EMC85284.1 - 7.3e-05 22.3 12.6 7.3e-05 22.3 8.7 1.9 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.19 EMC85284.1 - 2.3 8.1 9.1 5.1 7.0 6.3 1.6 1 0 0 1 1 1 0 B-box zinc finger Sep15_SelM PF08806.6 EMC85285.1 - 3.4e-22 77.9 0.0 3.7e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain zf-H2C2_2 PF13465.1 EMC85291.1 - 1.5e-22 78.6 32.5 3.5e-07 30.1 0.1 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC85291.1 - 1.4e-15 56.5 45.3 2.2e-05 24.5 0.3 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC85291.1 - 1.4e-07 31.3 43.6 0.00047 20.2 0.2 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC85291.1 - 0.0021 18.1 27.2 0.24 11.5 0.0 6.0 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC85291.1 - 0.068 13.1 34.9 0.064 13.1 2.6 6.6 6 1 0 6 6 6 0 C2H2-type zinc finger GAGA PF09237.6 EMC85291.1 - 0.093 12.3 0.1 0.093 12.3 0.1 2.5 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.2 EMC85291.1 - 0.15 12.2 0.1 0.15 12.2 0.1 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EMC85291.1 - 8.4 6.8 33.2 0.3 11.3 1.6 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain AAA PF00004.24 EMC85292.1 - 7.3e-38 129.7 0.0 1.3e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMC85292.1 - 1.5e-06 27.9 0.0 5.2e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 EMC85292.1 - 1.2e-05 24.5 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC85292.1 - 0.0016 18.6 0.6 0.15 12.1 0.4 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC85292.1 - 0.0022 17.7 0.1 0.012 15.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMC85292.1 - 0.0036 17.2 0.0 0.0078 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 EMC85292.1 - 0.0036 16.9 0.1 0.023 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC85292.1 - 0.011 15.7 1.1 0.22 11.4 0.8 2.4 1 1 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.8 EMC85292.1 - 0.023 13.4 0.0 0.053 12.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EMC85292.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EMC85292.1 - 0.079 12.3 0.8 3.8 6.8 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 EMC85292.1 - 0.081 12.6 1.2 0.24 11.1 0.3 2.1 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 EMC85292.1 - 0.13 11.4 0.1 0.29 10.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMC85292.1 - 0.26 11.1 1.2 1.5 8.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain Pyridoxal_deC PF00282.14 EMC85293.1 - 4.1e-167 555.3 0.0 5e-167 555.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMC85293.1 - 0.00018 20.7 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMC85293.1 - 0.001 18.0 0.0 0.0023 16.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EMC85294.1 - 8.9e-165 547.6 0.0 1.1e-164 547.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMC85294.1 - 0.0094 15.1 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase WH2 PF02205.15 EMC85295.1 - 2.2e-13 49.3 3.9 0.001 18.6 0.1 3.6 3 0 0 3 3 3 3 WH2 motif DsrD PF08679.6 EMC85296.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) MOR2-PAG1_N PF14222.1 EMC85296.1 - 0.033 12.8 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal DNA_ligase_A_N PF04675.9 EMC85296.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 DNA ligase N terminus V-set PF07686.12 EMC85297.1 - 2.6e-10 40.1 0.1 6.7e-10 38.8 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC85297.1 - 2.7e-08 33.5 1.8 4e-07 29.7 1.2 2.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC85297.1 - 5.1e-05 23.3 0.4 0.015 15.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC85297.1 - 8.9e-05 22.5 0.2 0.00022 21.2 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 EMC85297.1 - 0.032 12.5 0.4 0.17 10.0 0.0 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Ig_3 PF13927.1 EMC85297.1 - 0.062 13.8 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin domain C_tripleX PF02363.14 EMC85298.1 - 0.79 9.9 64.5 0.39 10.8 4.4 6.5 6 0 0 6 6 6 0 Cysteine rich repeat Acyl-CoA_dh_1 PF00441.19 EMC85299.1 - 5.7e-11 42.7 0.8 6.7e-11 42.4 0.5 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MORN PF02493.15 EMC85300.1 - 9.4e-10 37.6 7.2 5.6 6.8 0.0 7.1 7 1 1 8 8 8 5 MORN repeat DUF3842 PF12953.2 EMC85300.1 - 0.053 13.6 6.8 86 3.2 0.0 5.1 1 1 5 6 6 6 0 Domain of unknown function (DUF3842) HutP PF09021.6 EMC85300.1 - 5.3 7.2 13.6 1.3e+02 2.7 1.0 4.9 1 1 2 3 3 3 0 HutP MORN PF02493.15 EMC85301.1 - 4e-13 48.2 5.2 4.3 7.2 0.0 7.4 7 0 0 7 7 7 6 MORN repeat DUF3842 PF12953.2 EMC85301.1 - 0.0023 18.1 8.5 56 3.9 0.0 5.5 1 1 5 6 6 6 0 Domain of unknown function (DUF3842) Romo1 PF10247.4 EMC85301.1 - 0.043 14.0 31.0 19 5.5 0.3 7.2 1 1 5 7 7 7 0 Reactive mitochondrial oxygen species modulator 1 HutP PF09021.6 EMC85301.1 - 1.7 8.8 17.9 92 3.2 0.1 5.8 1 1 5 6 6 6 0 HutP DUF2706 PF10913.3 EMC85302.1 - 1.2 8.8 10.8 0.79 9.3 3.9 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2706) ACBP PF00887.14 EMC85303.1 - 5.9e-27 93.1 0.5 6.4e-27 93.0 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein MDH PF02315.11 EMC85303.1 - 0.043 13.7 0.1 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Pkinase PF00069.20 EMC85304.1 - 2.7e-68 229.9 0.0 3.3e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85304.1 - 5.8e-34 117.3 0.0 7.9e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMC85304.1 - 0.0031 16.9 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMC85304.1 - 0.0055 15.7 0.1 0.012 14.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC85304.1 - 0.024 14.3 0.5 1.8 8.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FH2 PF02181.18 EMC85305.1 - 3.4e-10 39.3 0.8 5.5e-10 38.6 0.6 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain RhoGEF PF00621.15 EMC85305.1 - 0.1 12.4 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 RhoGEF domain Condensation PF00668.15 EMC85305.1 - 0.11 11.2 1.0 0.15 10.8 0.7 1.1 1 0 0 1 1 1 0 Condensation domain Myosin_head PF00063.16 EMC85306.1 - 1.6e-229 763.5 5.3 2.2e-229 763.0 3.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EMC85306.1 - 5.1e-46 156.4 0.1 1.9e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 Myosin tail AAA_18 PF13238.1 EMC85306.1 - 0.002 18.4 0.0 0.009 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain IQ PF00612.22 EMC85306.1 - 0.0073 15.8 0.6 0.0073 15.8 0.4 3.6 4 0 0 4 4 4 1 IQ calmodulin-binding motif AAA_22 PF13401.1 EMC85306.1 - 0.0074 16.4 0.0 0.029 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC85306.1 - 0.015 14.4 0.0 0.042 12.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EMC85306.1 - 0.019 15.7 0.5 0.33 11.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain CDK5_activator PF03261.10 EMC85307.1 - 3.2e-63 214.1 0.1 4.6e-63 213.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein PCI PF01399.22 EMC85308.1 - 3.3e-20 72.3 0.7 3.3e-20 72.3 0.5 2.3 3 0 0 3 3 3 1 PCI domain DDRGK PF09756.4 EMC85308.1 - 0.0034 16.8 0.1 0.0081 15.5 0.1 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_10 PF13374.1 EMC85308.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC85308.1 - 0.19 11.7 6.7 13 5.9 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC85308.1 - 0.41 10.6 12.7 1.1 9.1 1.7 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC85308.1 - 7.1 6.6 7.9 30 4.7 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Frizzled PF01534.12 EMC85309.1 - 2.5e-142 473.4 17.6 3.2e-142 473.1 12.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 EMC85309.1 - 1.3e-34 118.9 5.8 2.5e-34 118.1 4.0 1.5 1 0 0 1 1 1 1 Fz domain Ndc1_Nup PF09531.5 EMC85309.1 - 0.17 10.2 2.5 0.27 9.6 1.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-DHHC PF01529.15 EMC85309.1 - 8.5 5.7 13.6 1.7 8.0 1.2 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase Integrin_alpha2 PF08441.7 EMC85310.1 - 1.1e-32 113.4 0.0 1.3e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Integrin alpha Alpha_adaptinC2 PF02883.15 EMC85310.1 - 0.12 12.6 0.0 4.5 7.6 0.0 2.6 2 1 1 3 3 3 0 Adaptin C-terminal domain GCIP PF13324.1 EMC85311.1 - 4.2e-08 32.7 0.1 5.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting FAM163 PF15069.1 EMC85311.1 - 0.11 13.1 1.0 0.14 12.7 0.5 1.3 1 1 0 1 1 1 0 FAM163 family RhoGAP PF00620.22 EMC85312.1 - 3.5e-39 133.8 0.0 1.4e-37 128.6 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain WW PF00397.21 EMC85312.1 - 4.8e-16 58.2 16.9 1e-08 34.8 0.3 3.5 3 0 0 3 3 3 2 WW domain PH PF00169.24 EMC85312.1 - 1.4e-09 38.0 0.0 5.8e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EMC85312.1 - 5.8e-08 32.9 0.1 1.1e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_9 PF14604.1 EMC85312.1 - 0.00016 21.1 0.0 0.00042 19.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC85312.1 - 0.00089 18.6 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF4206 PF13901.1 EMC85313.1 - 6.8e-41 140.0 9.2 7.9e-41 139.8 6.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) zf-UDP PF14569.1 EMC85313.1 - 0.007 16.0 6.7 0.014 15.1 4.7 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger C1_1 PF00130.17 EMC85313.1 - 0.014 15.1 12.4 0.15 11.8 8.6 2.3 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMC85313.1 - 0.068 12.9 15.3 0.42 10.3 10.6 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EMC85313.1 - 0.071 12.8 12.0 0.29 10.8 6.1 2.9 2 1 0 2 2 2 0 PHD-finger zf-MYND PF01753.13 EMC85313.1 - 0.28 11.0 8.4 0.37 10.7 0.3 2.8 2 1 0 2 2 2 0 MYND finger OrfB_Zn_ribbon PF07282.6 EMC85313.1 - 6.3 6.5 12.6 3.5 7.3 3.7 2.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain RUN PF02759.14 EMC85314.1 - 1.8e-24 85.9 0.1 2.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 RUN domain Hormone_1 PF00103.15 EMC85315.1 - 5.4e-47 159.9 0.0 6.2e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family DUF3469 PF11952.3 EMC85315.1 - 0.096 12.3 0.0 13 5.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3469) V-set PF07686.12 EMC85316.1 - 2.3e-07 30.6 0.3 4.1e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC85316.1 - 3.9e-06 26.6 0.0 6.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC85316.1 - 0.023 14.7 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin domain DUF1717 PF05414.6 EMC85316.1 - 0.083 13.3 0.2 0.2 12.1 0.1 1.6 1 1 0 1 1 1 0 Viral domain of unknown function (DUF1717) ig PF00047.20 EMC85316.1 - 0.13 12.3 0.2 0.39 10.8 0.2 1.8 1 1 0 1 1 1 0 Immunoglobulin domain Tmemb_9 PF05434.6 EMC85317.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 TMEM9 DUF1072 PF06380.6 EMC85317.1 - 0.27 10.9 7.6 0.86 9.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) GCC2_GCC3 PF07699.8 EMC85318.1 - 3.1e-05 23.4 0.4 5.5e-05 22.6 0.3 1.5 1 0 0 1 1 1 1 GCC2 and GCC3 7TM_GPCR_Srh PF10318.4 EMC85318.1 - 0.033 13.0 0.2 0.036 12.8 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Shisa PF13908.1 EMC85318.1 - 0.073 13.2 0.1 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sp38 PF07354.7 EMC85319.1 - 8.4e-15 54.1 0.0 1.1e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) V-set PF07686.12 EMC85319.1 - 5.5e-05 23.0 0.1 0.00097 19.0 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC85319.1 - 7.3e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC85319.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC85319.1 - 0.023 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain 7tm_2 PF00002.19 EMC85320.1 - 1.7e-77 259.8 21.9 2.2e-77 259.4 15.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC85320.1 - 6.3e-18 64.5 2.7 6.5e-18 64.5 1.1 1.7 2 0 0 2 2 2 1 Hormone receptor domain DUF2976 PF11190.3 EMC85320.1 - 0.24 10.9 4.1 4.7 6.8 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) ASC PF00858.19 EMC85321.1 - 5.3e-43 147.2 0.0 5.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel PT PF04886.7 EMC85322.1 - 9.5e-09 34.4 0.3 0.017 14.4 0.0 4.0 2 2 1 3 3 3 2 PT repeat ASC PF00858.19 EMC85323.1 - 8.3e-74 248.8 1.3 4.8e-59 200.1 0.0 2.0 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel PCIF1_WW PF12237.3 EMC85323.1 - 0.12 11.6 0.1 5.7 6.2 0.0 2.5 2 1 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain Acyltransferase PF01553.16 EMC85325.1 - 7.6e-13 48.0 0.0 8.5e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 EMC85326.1 - 2.5e-12 46.3 0.1 2.8e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Acyltransferase DUF3815 PF12821.2 EMC85326.1 - 0.065 13.1 0.1 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) DUF4587 PF15248.1 EMC85327.1 - 2.4e-17 63.3 2.4 9.5e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4587) 7tm_2 PF00002.19 EMC85328.1 - 9.2e-80 267.2 19.4 1.3e-79 266.6 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC85328.1 - 3.3e-14 52.6 1.5 3.3e-14 52.6 1.0 2.2 3 0 0 3 3 3 1 Hormone receptor domain Dicty_CAR PF05462.6 EMC85328.1 - 0.003 16.5 18.1 0.0042 16.0 12.6 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor UAA PF08449.6 EMC85329.1 - 9.1e-62 208.6 3.0 1e-61 208.4 2.1 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMC85329.1 - 9.4e-15 54.5 9.9 7.1e-13 48.4 4.8 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EMC85329.1 - 7.4e-14 51.8 12.5 1.1e-10 41.6 5.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EMC85329.1 - 9e-10 38.7 11.9 6.9e-05 23.0 6.3 2.1 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EMC85329.1 - 0.0075 15.3 0.8 1.2 8.1 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter UPF0546 PF10639.4 EMC85329.1 - 0.22 11.3 2.3 1.4 8.7 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 BTB PF00651.26 EMC85330.1 - 2e-33 114.6 1.9 1.2e-32 112.1 0.2 2.2 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.21 EMC85330.1 - 2e-10 40.9 0.1 7.2e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 MATH domain BACK PF07707.10 EMC85330.1 - 0.0011 18.7 0.8 0.1 12.4 0.0 3.3 4 0 0 4 4 4 1 BTB And C-terminal Kelch Neurexophilin PF06312.7 EMC85331.1 - 1.2e-102 341.8 0.2 1.4e-102 341.5 0.1 1.0 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.14 EMC85331.1 - 0.0062 17.0 0.1 0.32 11.5 0.0 2.2 1 1 1 2 2 2 1 Filamin/ABP280 repeat NigD PF12667.2 EMC85331.1 - 0.048 13.4 0.1 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 NigD-like protein CHORD PF04968.7 EMC85331.1 - 6.4 7.1 8.2 0.63 10.3 2.7 1.6 2 0 0 2 2 2 0 CHORD TNFR_c6 PF00020.13 EMC85332.1 - 6.8e-32 109.2 46.9 1.6e-10 40.8 4.7 4.1 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region DUF3762 PF12591.3 EMC85332.1 - 0.024 14.6 0.4 0.06 13.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Band_7 PF01145.20 EMC85333.1 - 2.8e-08 33.8 3.1 2.8e-08 33.8 1.8 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 EMC85333.1 - 0.012 15.6 0.8 0.017 15.1 0.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 IRF-2BP1_2 PF11261.3 EMC85333.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger G-gamma PF00631.17 EMC85334.1 - 1.9e-17 62.7 0.0 2e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain TPD52 PF04201.10 EMC85334.1 - 0.015 14.9 2.1 0.018 14.7 1.4 1.1 1 0 0 1 1 1 0 Tumour protein D52 family Herpes_UL25 PF01499.11 EMC85334.1 - 0.037 12.3 0.1 0.037 12.3 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF904 PF06005.7 EMC85334.1 - 0.045 14.0 2.2 0.048 13.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) ORF11CD3 PF10549.4 EMC85334.1 - 0.054 13.2 0.4 0.077 12.7 0.2 1.3 1 0 0 1 1 1 0 ORF11CD3 domain Cwf_Cwc_15 PF04889.7 EMC85334.1 - 0.067 12.8 3.4 0.079 12.6 2.3 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma54_AID PF00309.15 EMC85334.1 - 0.088 12.2 0.3 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Bacillus_HBL PF05791.6 EMC85334.1 - 0.12 11.7 0.8 0.12 11.6 0.5 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3294 PF07957.6 EMC85334.1 - 0.22 11.0 3.0 0.25 10.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) KH_1 PF00013.24 EMC85335.1 - 6.8e-55 182.5 12.1 1.7e-13 50.0 0.2 4.5 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 EMC85335.1 - 3.1e-36 122.4 12.2 1.2e-08 34.3 0.1 4.7 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 EMC85335.1 - 2.8e-19 68.4 2.6 0.0005 19.5 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 EMC85335.1 - 1.5e-15 56.5 1.1 0.0016 18.0 0.0 5.0 5 0 0 5 5 5 4 KH domain KH_5 PF13184.1 EMC85335.1 - 3.2e-09 36.4 2.8 0.11 12.3 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain RRM_1 PF00076.17 EMC85335.1 - 1.6e-08 34.0 0.0 3.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85335.1 - 6.9e-06 25.8 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC85335.1 - 3.9e-05 23.5 0.0 8.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) dUTPase PF00692.14 EMC85335.1 - 0.044 13.2 0.1 18 4.7 0.0 3.1 4 0 0 4 4 4 0 dUTPase YtzH PF14165.1 EMC85335.1 - 0.14 12.4 4.2 0.85 9.8 0.2 3.2 3 1 1 4 4 4 0 YtzH-like protein Hormone_2 PF00123.15 EMC85336.1 - 8.1e-08 31.9 0.3 8.1e-08 31.9 0.2 2.0 2 0 0 2 2 2 1 Peptide hormone EAP30 PF04157.11 EMC85337.1 - 1.2e-66 224.1 0.1 1.3e-66 223.9 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Apolipoprotein PF01442.13 EMC85337.1 - 0.014 14.8 4.6 0.072 12.5 0.2 2.4 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Sigma70_r1_1 PF03979.9 EMC85337.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 TrmB PF01978.14 EMC85337.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MotA_activ PF09114.5 EMC85337.1 - 0.086 12.5 0.1 0.34 10.6 0.0 2.2 1 1 0 1 1 1 0 Transcription factor MotA, activation domain DUF1342 PF07072.6 EMC85337.1 - 0.18 11.4 2.7 16 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1342) UQ_con PF00179.21 EMC85338.1 - 1.2e-30 105.8 0.1 1.9e-30 105.1 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EMC85338.1 - 0.00017 21.2 2.6 0.00062 19.4 0.0 2.5 3 0 0 3 3 3 1 UEV domain RWD PF05773.17 EMC85338.1 - 0.027 14.3 0.8 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 RWD domain Prok-E2_B PF14461.1 EMC85338.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B CALCOCO1 PF07888.6 EMC85339.1 - 3.1e-33 114.9 17.9 7.1e-33 113.7 12.4 1.6 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like TBPIP PF07106.8 EMC85339.1 - 3.1e-05 23.5 32.7 0.00015 21.3 12.1 2.1 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF904 PF06005.7 EMC85339.1 - 4.3e-05 23.7 40.8 0.046 14.0 8.6 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF904) HOOK PF05622.7 EMC85339.1 - 7.7e-05 20.7 25.5 0.00012 20.0 17.6 1.2 1 0 0 1 1 1 1 HOOK protein IncA PF04156.9 EMC85339.1 - 0.00037 20.1 37.6 0.0012 18.4 19.8 2.2 1 1 1 2 2 2 1 IncA protein GAS PF13851.1 EMC85339.1 - 0.00099 18.3 30.4 0.023 13.8 9.5 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Syntaxin PF00804.20 EMC85339.1 - 0.0012 18.9 12.0 0.0012 18.9 8.3 2.3 1 1 1 2 2 2 1 Syntaxin WEMBL PF05701.6 EMC85339.1 - 0.0017 16.9 23.5 0.0024 16.4 16.3 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light bZIP_1 PF00170.16 EMC85339.1 - 0.0039 17.0 2.6 0.0039 17.0 1.8 4.2 3 1 1 4 4 4 1 bZIP transcription factor zf-C2H2_4 PF13894.1 EMC85339.1 - 0.0046 17.2 6.0 1.3 9.4 0.0 3.2 1 1 1 2 2 2 1 C2H2-type zinc finger EMP24_GP25L PF01105.19 EMC85339.1 - 0.0082 15.8 1.5 0.0082 15.8 1.0 3.7 1 1 1 3 3 3 1 emp24/gp25L/p24 family/GOLD zinc_ribbon_5 PF13719.1 EMC85339.1 - 0.029 13.9 1.1 2 8.0 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Reo_sigmaC PF04582.7 EMC85339.1 - 0.033 13.3 8.6 0.4 9.7 0.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein RmuC PF02646.11 EMC85339.1 - 0.046 12.5 19.0 0.076 11.8 2.0 2.1 1 1 1 2 2 2 0 RmuC family zinc_ribbon_4 PF13717.1 EMC85339.1 - 0.048 13.3 1.1 2.5 7.8 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain GldM_N PF12081.3 EMC85339.1 - 0.049 13.1 9.3 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 GldM N-terminal domain zf-C2HC_2 PF13913.1 EMC85339.1 - 0.063 12.9 1.5 0.84 9.3 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF848 PF05852.6 EMC85339.1 - 0.073 12.9 23.6 0.05 13.4 3.8 2.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ADIP PF11559.3 EMC85339.1 - 0.084 12.7 37.3 0.09 12.6 7.4 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CCDC155 PF14662.1 EMC85339.1 - 0.097 12.2 34.4 0.37 10.3 23.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 EMC85339.1 - 0.25 11.2 37.7 0.13 12.1 15.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMCO5 PF14992.1 EMC85339.1 - 0.86 8.6 26.7 1.7 7.6 18.5 1.5 1 0 0 1 1 1 0 TMCO5 family Lipoprotein_20 PF13942.1 EMC85339.1 - 0.98 8.9 18.3 0.34 10.4 2.6 2.3 2 0 0 2 2 2 0 YfhG lipoprotein LMBR1 PF04791.11 EMC85339.1 - 1.1 7.7 4.4 1.7 7.1 3.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ax_dynein_light PF10211.4 EMC85339.1 - 1.7 8.4 27.4 0.059 13.2 5.8 2.9 1 1 2 3 3 3 0 Axonemal dynein light chain zf-H2C2_2 PF13465.1 EMC85339.1 - 2 8.8 7.8 1.6 9.1 0.2 3.1 3 0 0 3 3 2 0 Zinc-finger double domain BLOC1_2 PF10046.4 EMC85339.1 - 2.1 8.5 21.0 0.6 10.2 8.6 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rab5-bind PF09311.6 EMC85339.1 - 2.1 8.1 35.2 8.5 6.2 24.0 2.1 1 1 0 1 1 1 0 Rabaptin-like protein TMF_TATA_bd PF12325.3 EMC85339.1 - 2.8 7.6 32.2 2.1 8.0 11.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-C2H2 PF00096.21 EMC85339.1 - 2.9 8.4 6.4 12 6.4 0.3 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF641 PF04859.7 EMC85339.1 - 3.1 7.5 17.6 3.6 7.3 3.7 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Occludin_ELL PF07303.8 EMC85339.1 - 3.2 8.5 15.7 0.28 11.9 6.1 2.4 1 1 1 2 2 2 0 Occludin homology domain DUF972 PF06156.8 EMC85339.1 - 3.4 8.0 31.6 5 7.5 4.7 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EMC85339.1 - 4.3 6.8 35.2 0.68 9.4 2.4 4.8 2 2 1 4 4 4 0 Septum formation initiator Tropomyosin_1 PF12718.2 EMC85339.1 - 4.7 7.0 36.6 6 6.7 14.8 2.2 1 1 2 3 3 3 0 Tropomyosin like HlyD PF00529.15 EMC85339.1 - 5.5 6.1 15.4 6.2 6.0 9.3 1.8 1 1 0 1 1 1 0 HlyD family secretion protein TSC22 PF01166.13 EMC85339.1 - 5.9 6.9 32.4 0.35 10.8 4.2 4.0 1 1 3 4 4 4 0 TSC-22/dip/bun family WD40_alt PF14077.1 EMC85339.1 - 5.9 6.6 20.4 0.73 9.5 0.1 3.5 4 0 0 4 4 3 0 Alternative WD40 repeat motif FUSC PF04632.7 EMC85339.1 - 7.3 4.8 5.5 10 4.4 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.3 EMC85339.1 - 7.7 5.7 26.2 5.4 6.1 4.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Homeobox PF00046.24 EMC85340.1 - 8.5e-20 70.1 5.3 9.3e-20 70.0 3.7 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC85340.1 - 8e-05 22.2 0.8 8.9e-05 22.1 0.6 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC85340.1 - 0.037 13.0 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.1 EMC85340.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Hox9_act PF04617.8 EMC85341.1 - 9.5e-56 188.8 2.7 1.4e-55 188.3 1.9 1.2 1 0 0 1 1 1 1 Hox9 activation region Homeobox PF00046.24 EMC85341.1 - 2.4e-21 75.0 6.1 4e-21 74.3 4.2 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EMC85341.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 EMC85342.1 - 2.5e-22 78.2 5.5 4.4e-22 77.4 3.8 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC85342.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain MRP-63 PF14978.1 EMC85342.1 - 0.097 13.1 3.6 0.2 12.0 2.1 1.8 1 1 0 1 1 1 0 Mitochondrial ribosome protein 63 Homeobox PF00046.24 EMC85343.1 - 3.7e-22 77.6 7.8 5.5e-22 77.1 5.4 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC85343.1 - 0.015 14.9 0.8 0.03 14.0 0.5 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 EMC85344.1 - 2.8e-22 78.1 8.2 4.3e-22 77.4 5.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC85344.1 - 0.018 14.7 1.1 0.042 13.5 0.7 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 EMC85345.1 - 2e-22 78.5 8.1 3.9e-22 77.6 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC85345.1 - 0.015 15.0 1.0 0.054 13.2 0.7 2.0 1 0 0 1 1 1 0 Homeobox KN domain Menin PF05053.8 EMC85345.1 - 1.2 7.1 6.8 1.6 6.7 4.7 1.1 1 0 0 1 1 1 0 Menin Homeobox PF00046.24 EMC85346.1 - 1.8e-22 78.6 8.1 1.8e-22 78.6 5.6 1.6 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EMC85346.1 - 0.02 14.5 0.4 0.049 13.3 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.4 EMC85346.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Pox_F17 PF04767.7 EMC85346.1 - 1.9 8.7 4.7 0.75 10.0 0.8 2.1 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein DUF4074 PF13293.1 EMC85347.1 - 4.7e-34 116.4 10.3 4.7e-34 116.4 7.2 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4074) Homeobox PF00046.24 EMC85347.1 - 9.5e-09 34.7 11.8 0.00018 21.0 0.2 2.8 2 1 1 3 3 3 2 Homeobox domain CDC27 PF09507.5 EMC85347.1 - 0.17 11.0 8.2 0.28 10.3 5.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Homeobox PF00046.24 EMC85348.1 - 2e-22 78.5 7.2 3.1e-22 77.9 5.0 1.3 1 0 0 1 1 1 1 Homeobox domain PH PF00169.24 EMC85350.1 - 2.8e-09 37.1 0.8 3.3e-09 36.8 0.6 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC85350.1 - 8.4e-05 22.8 0.7 0.0001 22.5 0.5 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMC85350.1 - 0.021 14.7 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 PH domain Chromo_shadow PF01393.14 EMC85351.1 - 5.3e-39 131.8 0.1 4.2e-34 116.1 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 EMC85351.1 - 3.9e-24 84.0 3.7 5e-19 67.7 0.4 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EMC85351.1 - 0.0024 17.7 0.1 0.006 16.4 0.2 1.6 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 Clat_adaptor_s PF01217.15 EMC85352.1 - 3.7e-25 88.3 0.0 4e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF773 PF05600.7 EMC85353.1 - 4.9e-43 147.6 0.0 5.5e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF773) Peptidase_C69 PF03577.10 EMC85355.1 - 7.3e-09 34.9 0.0 1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 EMC85355.1 - 0.11 11.9 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF3967 PF13152.1 EMC85355.1 - 0.47 10.1 2.1 0.85 9.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) LRR_4 PF12799.2 EMC85356.1 - 8.1e-15 54.0 3.6 1.3e-06 27.9 0.2 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC85356.1 - 1.3e-08 34.5 3.5 2.7e-08 33.4 1.6 2.2 1 1 1 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EMC85356.1 - 2.2e-07 29.9 5.2 0.0023 17.7 0.1 4.0 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC85356.1 - 4e-06 26.1 7.2 0.029 14.4 0.1 4.0 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.1 EMC85356.1 - 7.9e-05 22.2 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EMC85356.1 - 0.00017 21.2 0.8 0.081 13.0 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeat PRNT PF15174.1 EMC85356.1 - 0.079 12.6 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Prion-related protein testis-specific T-box PF00907.17 EMC85357.1 - 2.2e-35 121.8 0.7 3e-31 108.3 0.0 2.2 1 1 1 2 2 2 2 T-box HEAT PF02985.17 EMC85358.1 - 2.4e-18 64.5 8.8 4.2e-05 23.2 0.0 10.0 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EMC85358.1 - 6.2e-18 64.7 2.0 1.6e-09 37.9 0.0 7.8 8 2 2 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 EMC85358.1 - 1e-15 57.7 0.3 1.5e-05 25.1 0.0 6.4 3 1 5 9 9 9 5 HEAT repeats IBN_N PF03810.14 EMC85358.1 - 1e-12 47.7 0.4 1.4e-11 44.1 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 EMC85358.1 - 8.5e-10 38.0 4.7 0.0016 18.1 0.0 6.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EMC85358.1 - 4.7e-05 22.8 4.2 0.41 9.9 0.0 4.3 3 1 1 4 4 4 2 CLASP N terminal UME PF08064.8 EMC85358.1 - 0.023 14.6 2.5 5 7.1 0.0 4.7 4 1 0 4 4 4 0 UME (NUC010) domain RIX1 PF08167.7 EMC85358.1 - 0.2 11.3 4.0 49 3.5 0.0 4.6 4 2 0 4 4 4 0 rRNA processing/ribosome biogenesis Peptidase_M1 PF01433.15 EMC85359.1 - 3.3e-141 470.8 0.0 4.5e-141 470.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMC85359.1 - 4e-58 197.1 0.0 9e-58 196.0 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMC85359.1 - 8.7e-23 80.7 0.3 1.8e-22 79.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily tRNA_anti-codon PF01336.20 EMC85359.1 - 0.097 12.5 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain NatB_MDM20 PF09797.4 EMC85359.1 - 0.2 10.3 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Tim44 PF04280.10 EMC85360.1 - 1.4e-27 96.4 0.0 1.9e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 EMC85360.1 - 0.00086 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein ChaB PF06150.7 EMC85360.1 - 0.0095 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 ChaB Kri1 PF05178.7 EMC85360.1 - 0.086 13.1 0.2 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 KRI1-like family DUF326 PF03860.11 EMC85361.1 - 1.2e-07 31.1 47.3 33 4.5 5.7 8.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF326) PLATZ PF04640.9 EMC85361.1 - 0.079 13.1 25.1 6.9 6.9 5.0 4.3 1 1 2 3 3 3 0 PLATZ transcription factor TMEM191C PF15194.1 EMC85361.1 - 0.08 12.8 7.0 4.5 7.1 0.2 3.2 1 1 2 3 3 3 0 TMEM191C family DUF1289 PF06945.8 EMC85361.1 - 0.17 11.3 31.7 4.9 6.7 2.7 5.8 1 1 6 7 7 7 0 Protein of unknown function (DUF1289) HSA PF07529.8 EMC85361.1 - 1.7 8.5 17.1 33 4.3 0.2 4.9 1 1 3 4 4 4 0 HSA DUF4001 PF13165.1 EMC85361.1 - 1.9 8.2 39.7 0.13 11.9 4.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF4001) DUF3384 PF11864.3 EMC85361.1 - 6.7 5.0 7.6 16 3.8 0.1 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF3384) NUMOD1 PF07453.8 EMC85362.1 - 2.4e-09 36.7 14.8 41 4.2 0.0 11.5 8 8 8 16 16 16 0 NUMOD1 domain HTH_Tnp_IS1 PF12759.2 EMC85362.1 - 2.4e-05 23.6 14.2 57 3.2 0.0 8.7 8 0 0 8 8 8 0 InsA C-terminal domain Colipase-like PF15083.1 EMC85362.1 - 0.0021 17.9 35.4 0.39 10.6 2.1 4.5 1 1 5 6 6 6 6 Colipase-like DUF3437 PF11919.3 EMC85362.1 - 0.0033 17.1 20.6 35 4.1 0.1 7.4 1 1 10 11 11 11 0 Domain of unknown function (DUF3437) Activator-TraM PF11657.3 EMC85362.1 - 0.32 10.4 6.7 71 2.8 0.1 4.3 1 1 6 7 7 7 0 Transcriptional activator TraM DUF687 PF05095.7 EMC85362.1 - 2.3 6.4 14.6 66 1.6 0.0 6.1 1 1 5 7 7 7 0 Protein of unknown function (DUF687) SOCS_box PF07525.11 EMC85363.1 - 2.5e-13 49.6 3.3 6e-13 48.4 2.3 1.7 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 EMC85363.1 - 2.8e-09 36.6 0.0 7.1e-09 35.3 0.0 1.7 1 1 1 2 2 2 1 SH2 domain PDZ PF00595.19 EMC85365.1 - 0.015 15.4 0.2 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) RhoGAP PF00620.22 EMC85366.1 - 3.9e-24 85.0 0.0 4.6e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain Ski_Sno PF02437.12 EMC85368.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 SKI/SNO/DAC family zf-HC5HC2H_2 PF13832.1 EMC85369.1 - 3.5e-30 104.2 11.4 6.3e-30 103.4 7.9 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC85369.1 - 1.1e-19 70.3 10.4 2.9e-19 68.9 7.2 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain HALZ PF02183.13 EMC85369.1 - 3 7.6 10.4 0.049 13.3 1.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2180 PF09947.4 EMC85369.1 - 5.9 6.7 10.2 2.1 8.1 3.4 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Rad60-SLD PF11976.3 EMC85371.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_C36 PF05415.6 EMC85372.1 - 0.0033 17.2 20.2 1.4 8.8 1.1 4.9 1 1 3 4 4 4 4 Beet necrotic yellow vein furovirus-type papain-like endopeptidase SpoU_methylas_C PF12105.3 EMC85372.1 - 0.013 15.0 0.7 12 5.5 0.0 4.0 2 1 2 4 4 4 0 SpoU, rRNA methylase, C-terminal Equine_IAV_S2 PF06502.6 EMC85372.1 - 1 9.2 34.7 6.8 6.6 0.0 8.4 1 1 6 8 8 8 0 Equine infectious anaemia virus S2 protein DUF4033 PF13225.1 EMC85372.1 - 1.5 8.5 52.1 2.3 7.8 4.0 6.1 1 1 6 7 7 7 0 Domain of unknown function (DUF4033) Peptidase_C36 PF05415.6 EMC85373.1 - 5.5e-05 22.9 7.3 0.98 9.3 0.2 4.0 1 1 3 4 4 4 3 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Equine_IAV_S2 PF06502.6 EMC85373.1 - 0.0001 22.0 12.7 1.7 8.5 0.1 5.3 1 1 4 5 5 5 3 Equine infectious anaemia virus S2 protein SpoU_methylas_C PF12105.3 EMC85373.1 - 0.00013 21.4 0.1 20 4.8 0.0 4.1 1 1 3 4 4 4 0 SpoU, rRNA methylase, C-terminal DUF4033 PF13225.1 EMC85373.1 - 0.0028 17.2 32.5 0.98 9.0 1.8 4.8 1 1 3 4 4 4 4 Domain of unknown function (DUF4033) NHL PF01436.16 EMC85373.1 - 0.011 15.6 22.1 30 4.8 0.2 7.3 1 1 8 9 9 9 0 NHL repeat Mycobact_memb PF05423.8 EMC85373.1 - 0.019 14.7 11.1 8.3 6.1 0.1 4.0 1 1 3 4 4 4 0 Mycobacterium membrane protein Ldr_toxin PF13940.1 EMC85373.1 - 0.25 11.1 1.4 2.4e+02 1.5 0.0 3.9 4 0 0 4 4 4 0 Toxin Ldr, type I toxin-antitoxin system Herpes_U34 PF04541.8 EMC85373.1 - 1.4 7.7 14.0 11 4.8 0.4 3.7 1 1 3 4 4 4 0 Herpesvirus virion protein U34 DBD_Tnp_Hermes PF10683.4 EMC85373.1 - 5.3 6.5 12.5 18 4.8 0.6 3.3 1 1 2 3 3 3 0 Hermes transposase DNA-binding domain PIP5K PF01504.13 EMC85374.1 - 4.5e-75 252.0 0.1 5.4e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CWC25 PF12542.3 EMC85375.1 - 3.3e-20 72.3 0.0 3.3e-20 72.3 0.0 4.1 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EMC85375.1 - 2.5e-15 56.1 11.8 2.5e-15 56.1 8.2 6.2 6 1 1 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR tRNA-synt_1c PF00749.16 EMC85375.1 - 0.00052 18.7 3.9 0.00052 18.7 2.7 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_L14 PF00238.14 EMC85376.1 - 3e-35 120.6 0.1 3.3e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF4064 PF13273.1 EMC85377.1 - 0.025 14.6 0.3 0.054 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Ribosomal_L19e PF01280.15 EMC85378.1 - 2.5e-44 150.6 12.7 2.5e-44 150.6 8.8 2.0 1 1 0 2 2 2 1 Ribosomal protein L19e LRR_6 PF13516.1 EMC85379.1 - 1.6e-22 76.9 28.6 0.0054 16.6 0.0 11.5 11 1 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 EMC85379.1 - 8.4e-15 54.0 15.1 0.019 14.5 0.4 6.7 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EMC85379.1 - 1.3e-13 50.4 0.6 4.7e-13 48.6 0.4 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EMC85379.1 - 6.3e-12 45.0 21.0 0.00019 21.0 2.7 6.0 3 3 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EMC85379.1 - 1.4e-10 39.6 26.0 1.4 9.2 0.1 11.8 11 1 0 11 11 11 3 Leucine Rich Repeat F-box PF00646.28 EMC85379.1 - 1.8e-07 30.6 0.7 1.8e-07 30.6 0.5 2.5 2 0 0 2 2 2 1 F-box domain LRR_7 PF13504.1 EMC85379.1 - 2.6e-06 26.7 22.7 0.96 9.9 0.0 10.3 10 1 0 10 10 10 2 Leucine rich repeat MENTAL PF10457.4 EMC85382.1 - 6.2e-73 244.0 7.6 9.7e-73 243.3 5.3 1.3 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.14 EMC85382.1 - 9.1e-45 152.5 0.0 1.3e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 START domain LRAT PF04970.8 EMC85383.1 - 1.7e-07 31.2 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 EMC85383.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 2 0 0 2 2 2 0 NlpC/P60 family Homeobox PF00046.24 EMC85385.1 - 1.1e-12 47.3 2.9 2.1e-12 46.4 0.8 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EMC85385.1 - 1.8e-09 37.1 0.5 4e-09 36.0 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.17 EMC85385.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.3 EMC85385.1 - 0.027 13.5 0.0 0.061 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez CENP-B_N PF04218.8 EMC85385.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_26 PF13443.1 EMC85385.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Methyltransf_16 PF10294.4 EMC85386.1 - 1e-16 60.8 0.1 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 EMC85386.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.7 EMC85386.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Methyltransf_23 PF13489.1 EMC85386.1 - 0.0033 17.1 0.0 0.034 13.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC85386.1 - 0.0034 16.9 0.2 0.0043 16.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC85386.1 - 0.0042 17.4 0.0 0.0069 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC85386.1 - 0.0047 17.3 0.0 0.013 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC85386.1 - 0.02 15.5 0.1 0.034 14.7 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMC85386.1 - 0.038 13.3 0.4 0.057 12.8 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Peptidase_S9 PF00326.16 EMC85387.1 - 2.9e-34 118.1 0.0 5.4e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 EMC85387.1 - 4e-23 81.6 3.8 6.4e-23 81.0 2.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.2 EMC85387.1 - 0.00028 20.8 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMC85387.1 - 0.00047 19.8 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC85387.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC85387.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Alpha-amylase PF00128.19 EMC85388.1 - 1.6e-70 238.0 2.2 2.7e-70 237.2 1.5 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Nup35_RRM_2 PF14605.1 EMC85388.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Alpha-amylase_C PF02806.13 EMC85388.1 - 0.04 14.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Renin_r PF07850.9 EMC85388.1 - 0.052 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Renin receptor-like protein PP2C PF00481.16 EMC85389.1 - 1.9e-83 279.7 0.0 2.4e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 EMC85389.1 - 1.9e-35 120.8 0.1 3.6e-35 119.8 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.1 EMC85389.1 - 2.5e-07 30.3 0.0 5.5e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMC85389.1 - 0.0029 17.3 0.0 0.93 9.1 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) BLOC1_2 PF10046.4 EMC85390.1 - 4.4e-33 113.3 8.2 5.3e-33 113.0 5.7 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ParB PF08775.5 EMC85390.1 - 0.0073 16.6 4.3 0.012 15.9 3.0 1.4 1 0 0 1 1 1 1 ParB family NPV_P10 PF05531.7 EMC85390.1 - 0.03 14.5 0.9 0.05 13.8 0.3 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phospholip_B PF04916.8 EMC85390.1 - 0.033 12.3 0.8 0.039 12.0 0.6 1.0 1 0 0 1 1 1 0 Phospholipase B DUF948 PF06103.6 EMC85390.1 - 0.078 12.8 0.4 0.38 10.6 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EMC85390.1 - 0.28 9.7 7.2 0.34 9.5 3.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 EMC85390.1 - 0.7 9.4 4.1 1.5 8.3 2.8 1.7 1 1 0 1 1 1 0 IncA protein CCDC155 PF14662.1 EMC85390.1 - 0.7 9.4 8.2 0.26 10.8 3.4 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 EMC85390.1 - 0.91 9.6 4.2 2.9 7.9 2.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 EMC85390.1 - 4.2 7.7 7.7 1.7 8.9 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EMC85390.1 - 8 6.0 9.6 1.6 8.2 2.9 2.3 2 1 1 3 3 3 0 Septum formation initiator PKD_channel PF08016.7 EMC85391.1 - 5.7e-158 525.8 17.7 5.7e-158 525.8 12.3 1.4 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 EMC85391.1 - 4e-26 91.5 30.4 4e-26 91.5 21.1 1.8 2 0 0 2 2 2 1 Ion transport protein EF-hand_8 PF13833.1 EMC85391.1 - 0.00036 20.0 4.3 0.0015 18.0 0.6 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EMC85391.1 - 0.0046 17.0 2.2 0.024 14.7 1.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC85391.1 - 0.053 13.4 3.9 1.4 8.9 0.1 3.6 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 EMC85391.1 - 0.061 12.6 6.5 0.22 10.9 0.1 3.6 4 0 0 4 4 4 0 EF hand SPARC_Ca_bdg PF10591.4 EMC85391.1 - 0.79 9.7 4.0 0.95 9.5 1.3 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF360 PF04020.8 EMC85392.1 - 0.061 13.6 0.4 0.067 13.5 0.3 1.1 1 0 0 1 1 1 0 Membrane protein of unknown function EPTP PF03736.12 EMC85393.1 - 6.4e-96 313.9 20.7 1.1e-15 57.0 0.0 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 EMC85393.1 - 1.5e-23 82.2 9.0 1.5e-15 56.6 2.6 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EMC85393.1 - 4.7e-10 38.8 4.9 2.4e-05 23.8 1.4 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC85393.1 - 1.5e-07 31.1 0.5 1.5e-07 31.1 0.4 2.3 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC85393.1 - 4.8e-06 25.8 9.4 0.006 16.4 0.4 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.1 EMC85393.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 EMC85393.1 - 0.13 12.5 4.6 5.9 7.5 0.4 3.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 EMC85393.1 - 3.6 7.9 6.6 39 4.7 0.3 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Fra10Ac1 PF09725.4 EMC85394.1 - 1.4e-53 179.9 6.3 1.4e-53 179.9 4.4 2.0 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 DUF755 PF05501.6 EMC85394.1 - 0.0036 17.3 11.6 0.0036 17.3 8.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF755) SelP_N PF04592.9 EMC85394.1 - 0.032 13.6 4.5 0.062 12.6 3.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ChAPs PF09295.5 EMC85394.1 - 0.093 11.4 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) FYDLN_acid PF09538.5 EMC85394.1 - 0.8 10.3 19.3 0.22 12.1 7.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PDEase_I PF00233.14 EMC85395.1 - 6e-91 304.3 2.7 6e-91 304.3 1.9 2.0 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 EMC85395.1 - 1.8e-34 119.1 0.0 4.9e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EMC85395.1 - 1.6e-12 47.6 0.0 1e-07 32.0 0.0 2.7 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.1 EMC85395.1 - 3.1e-08 34.2 0.0 0.001 19.5 0.0 2.4 2 0 0 2 2 2 2 GAF domain DUF4316 PF14195.1 EMC85395.1 - 0.015 15.3 0.7 0.041 13.9 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Lipocalin PF00061.18 EMC85396.1 - 3.2e-23 82.3 0.0 4.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.7 EMC85396.1 - 1.3e-06 28.2 0.2 2.2e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.8 EMC85396.1 - 1.7e-05 24.5 0.4 5e-05 22.9 0.3 1.7 1 1 0 1 1 1 1 Triabin 7tm_1 PF00001.16 EMC85397.1 - 5.2e-37 127.3 24.3 6.2e-37 127.1 16.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EABR PF12180.3 EMC85398.1 - 1.5e-17 62.5 1.9 1.5e-17 62.5 1.3 2.6 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 NusB PF01029.13 EMC85398.1 - 0.043 13.8 0.8 0.043 13.8 0.5 3.9 2 1 1 3 3 3 0 NusB family ADIP PF11559.3 EMC85398.1 - 2.4 8.0 69.6 0.094 12.6 13.1 4.5 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding C2 PF00168.25 EMC85399.1 - 1.1e-84 278.3 7.8 4.9e-16 58.3 0.0 8.6 7 1 0 7 7 7 7 C2 domain FerB PF08150.7 EMC85399.1 - 3.9e-38 129.3 0.1 1e-37 128.0 0.0 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.7 EMC85399.1 - 3.8e-28 97.3 0.0 8.9e-28 96.1 0.0 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain FerA PF08165.6 EMC85399.1 - 2.4e-22 78.3 0.3 5e-22 77.3 0.2 1.6 1 0 0 1 1 1 1 FerA (NUC095) domain SIP PF04954.8 EMC85399.1 - 0.063 13.6 0.2 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Siderophore-interacting protein PI3K_C2 PF00792.19 EMC85399.1 - 0.083 12.6 0.5 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Phosphoinositide 3-kinase C2 GDC-P PF02347.11 EMC85399.1 - 1.1 7.9 0.0 1.9 7.1 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein p450 PF00067.17 EMC85400.1 - 6e-60 203.0 0.0 4.1e-54 183.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Homeobox PF00046.24 EMC85401.1 - 7.5e-18 63.9 3.4 1.5e-17 62.8 2.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC85401.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 EMC85401.1 - 0.095 11.7 2.3 0.2 10.7 0.8 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Kinesin PF00225.18 EMC85402.1 - 5.3e-116 386.9 0.2 5.3e-116 386.9 0.1 3.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bind PF13931.1 EMC85402.1 - 2.1e-42 144.6 2.4 2.1e-42 144.6 1.7 4.7 4 2 2 6 6 6 1 Kinesin-associated microtubule-binding Peptidase_M16 PF00675.15 EMC85403.1 - 4.2e-48 162.8 0.2 3.6e-46 156.6 0.1 2.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMC85403.1 - 9.5e-37 126.4 0.4 5.8e-21 75.0 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Sorb PF02208.11 EMC85403.1 - 0.17 11.2 0.3 0.53 9.7 0.2 1.8 1 0 0 1 1 1 0 Sorbin homologous domain RINGv PF12906.2 EMC85405.1 - 5e-14 52.0 9.9 7.5e-14 51.5 6.9 1.3 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.4 EMC85405.1 - 0.00038 20.0 0.1 0.0009 18.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.1 EMC85405.1 - 0.00055 19.7 6.0 0.0012 18.6 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EMC85405.1 - 0.034 14.0 5.7 0.075 13.0 3.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EMC85405.1 - 0.28 10.8 4.9 0.6 9.7 3.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CSL PF05207.8 EMC85405.1 - 0.51 9.8 3.4 1.7 8.2 2.4 1.8 1 1 0 1 1 1 0 CSL zinc finger PHD PF00628.24 EMC85405.1 - 2.3 8.0 8.3 3.9 7.2 5.8 1.4 1 0 0 1 1 1 0 PHD-finger RRM_1 PF00076.17 EMC85406.1 - 2.2e-12 46.4 0.0 2.9e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC85406.1 - 5.2e-07 29.5 0.0 2.1e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.7 EMC85406.1 - 0.028 13.9 0.6 0.068 12.7 0.4 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-CGNR PF11706.3 EMC85406.1 - 0.05 13.1 0.3 0.05 13.1 0.2 1.9 2 0 0 2 2 2 0 CGNR zinc finger HSP20 PF00011.16 EMC85406.1 - 0.061 13.1 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-B_box PF00643.19 EMC85406.1 - 0.087 12.7 6.3 0.23 11.3 4.4 1.6 1 0 0 1 1 1 0 B-box zinc finger SKG6 PF08693.5 EMC85406.1 - 0.75 9.1 2.5 1.7 8.0 1.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3535 PF12054.3 EMC85407.1 - 4e-138 460.7 5.8 3.8e-137 457.5 2.5 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EMC85407.1 - 7.8e-68 228.4 0.0 1.5e-67 227.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EMC85407.1 - 1.8e-20 71.1 21.7 0.0046 16.9 0.0 12.6 12 0 0 12 12 12 6 HEAT repeat HEAT_2 PF13646.1 EMC85407.1 - 3.3e-13 49.7 1.8 0.0013 18.9 0.1 7.2 4 2 2 6 6 6 5 HEAT repeats Helicase_C PF00271.26 EMC85407.1 - 4e-13 49.0 0.0 9.9e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EMC85407.1 - 2.7e-11 43.7 0.2 0.0091 16.3 0.0 5.3 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC85407.1 - 3.4e-09 36.9 11.2 0.0043 17.5 0.1 9.3 8 2 3 11 11 11 1 HEAT-like repeat Arm PF00514.18 EMC85407.1 - 0.029 14.1 5.5 0.097 12.5 0.1 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DSPc PF00782.15 EMC85408.1 - 1.8e-11 43.7 0.0 2.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC85408.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC85408.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Cyclin_C PF02984.14 EMC85409.1 - 4.5e-26 91.0 11.8 1.1e-25 89.8 0.5 2.9 3 0 0 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 EMC85409.1 - 3.8e-18 65.2 0.9 3.8e-18 65.2 0.6 2.5 3 1 1 4 4 4 1 Cyclin, N-terminal domain zf-C2H2_4 PF13894.1 EMC85410.1 - 0.00018 21.6 42.8 0.066 13.5 0.1 7.8 6 1 1 7 7 7 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC85410.1 - 0.0014 18.8 41.7 0.042 14.1 0.5 7.8 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC85410.1 - 0.0037 17.5 50.6 0.031 14.6 0.2 7.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type PhnA_Zn_Ribbon PF08274.7 EMC85410.1 - 1.4 8.7 8.3 0.17 11.7 1.6 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon SH2 PF00017.19 EMC85411.1 - 3.4e-11 42.7 0.1 6.7e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 SH2 domain DUF2862 PF11061.3 EMC85411.1 - 0.06 13.0 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) DNA_pol_B_thumb PF14791.1 EMC85412.1 - 7.4e-22 76.8 0.9 1.5e-21 75.8 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EMC85412.1 - 2.1e-21 75.2 0.4 5.8e-21 73.7 0.1 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EMC85412.1 - 5.3e-16 58.5 0.0 1.5e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 EMC85412.1 - 9.1e-09 35.3 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm BRCT PF00533.21 EMC85412.1 - 1.9e-06 27.8 0.0 6e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EMC85412.1 - 0.00019 21.6 0.0 0.00054 20.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.3 EMC85412.1 - 0.0083 16.0 0.0 0.03 14.2 0.0 2.0 1 1 0 1 1 1 1 Pathogenicity locus Sulfotransfer_1 PF00685.22 EMC85413.1 - 5.5e-13 48.7 0.0 6.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Homeobox PF00046.24 EMC85414.1 - 2.7e-20 71.7 4.9 3.6e-20 71.3 3.4 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC85414.1 - 0.0016 18.1 0.4 0.0028 17.3 0.3 1.4 1 0 0 1 1 1 1 Homeobox KN domain Phage_terminase PF10668.4 EMC85414.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage terminase small subunit HTH_29 PF13551.1 EMC85414.1 - 0.12 12.5 0.6 0.52 10.4 0.3 2.1 1 1 0 1 1 1 0 Winged helix-turn helix RasGEF PF00617.14 EMC85415.1 - 5.6e-24 84.9 1.3 5.6e-24 84.9 0.9 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EMC85415.1 - 1.6e-12 47.3 1.5 6.6e-12 45.4 0.4 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif Choline_kinase PF01633.15 EMC85415.1 - 0.021 14.4 0.7 4 6.9 0.0 3.4 2 1 0 3 3 3 0 Choline/ethanolamine kinase TPR_6 PF13174.1 EMC85415.1 - 0.41 11.2 1.7 73 4.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.1 EMC85416.1 - 3.2e-14 52.4 2.6 3.2e-14 52.4 1.8 2.9 3 1 0 3 3 3 1 Leucine rich repeat 7tm_2 PF00002.19 EMC85416.1 - 5.6e-14 51.8 6.6 1.1e-13 50.8 4.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) I-set PF07679.11 EMC85416.1 - 2.1e-07 30.7 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain GPS PF01825.16 EMC85416.1 - 2.1e-06 27.7 2.3 2.1e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain LRR_4 PF12799.2 EMC85416.1 - 5.9e-05 22.5 7.6 0.00062 19.3 0.4 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC85416.1 - 0.0012 18.5 8.2 0.17 12.0 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.1 EMC85416.1 - 0.0025 17.5 1.2 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC85416.1 - 0.1 12.7 3.4 1.4 9.2 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_7 PF13504.1 EMC85416.1 - 8.5 7.0 8.2 3.1 8.4 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat Neur_chan_LBD PF02931.18 EMC85418.1 - 5.4e-52 176.0 0.1 7.4e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC85418.1 - 7.6e-33 114.3 5.3 5.7e-30 104.9 1.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region GDA1_CD39 PF01150.12 EMC85419.1 - 2.5e-130 434.8 0.1 3.1e-130 434.5 0.1 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DDE_Tnp_IS1595 PF12762.2 EMC85419.1 - 0.055 13.3 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain SH3_9 PF14604.1 EMC85420.1 - 1.3e-54 181.5 5.7 4.5e-11 42.1 0.0 6.9 7 0 0 7 7 7 5 Variant SH3 domain SH3_1 PF00018.23 EMC85420.1 - 2.9e-52 173.8 0.2 3.8e-11 42.2 0.0 6.8 6 1 0 6 6 6 6 SH3 domain SH3_2 PF07653.12 EMC85420.1 - 2.9e-46 154.7 1.3 2.8e-07 29.9 0.0 6.5 6 0 0 6 6 6 6 Variant SH3 domain BAR PF03114.13 EMC85420.1 - 2.4e-45 154.8 4.2 2.4e-45 154.8 2.9 2.2 2 0 0 2 2 2 1 BAR domain RhoGEF PF00621.15 EMC85420.1 - 5.5e-41 140.4 0.7 5.5e-41 140.4 0.5 1.9 2 0 0 2 2 2 1 RhoGEF domain CNTF PF01110.12 EMC85420.1 - 0.023 13.9 4.8 0.023 13.9 1.0 2.2 2 0 0 2 2 2 0 Ciliary neurotrophic factor ABC_membrane PF00664.18 EMC85421.1 - 5.6e-74 248.9 33.7 1e-40 139.9 8.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC85421.1 - 1.2e-53 181.0 1.8 2.9e-29 102.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EMC85421.1 - 8.1e-09 35.0 6.0 0.0047 16.1 0.4 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC85421.1 - 3.3e-08 33.7 1.2 0.012 15.6 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EMC85421.1 - 1.5e-06 28.1 0.4 0.023 14.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EMC85421.1 - 2.5e-06 27.6 0.4 5.5 6.8 0.0 4.4 2 2 0 3 3 3 1 AAA domain Miro PF08477.8 EMC85421.1 - 5.2e-06 26.9 0.3 0.014 15.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EMC85421.1 - 1.4e-05 24.5 1.1 0.049 13.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMC85421.1 - 3.8e-05 22.9 0.2 0.29 10.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMC85421.1 - 0.00052 19.1 1.1 0.81 8.7 0.2 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 EMC85421.1 - 0.0013 18.2 4.0 0.19 11.1 0.0 3.5 3 1 0 3 3 3 1 AAA-like domain T2SE PF00437.15 EMC85421.1 - 0.0013 17.7 0.0 1.3 7.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EMC85421.1 - 0.0027 18.4 0.0 8.4 7.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EMC85421.1 - 0.0028 17.1 0.0 0.18 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMC85421.1 - 0.0033 16.3 0.3 0.71 8.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.12 EMC85421.1 - 0.0044 16.8 11.4 0.085 12.6 0.1 3.5 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EMC85421.1 - 0.007 16.5 0.7 11 6.2 0.3 3.4 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMC85421.1 - 0.0087 15.8 8.1 0.088 12.6 0.4 3.0 3 0 0 3 3 2 2 Dynamin family ArgK PF03308.11 EMC85421.1 - 0.015 14.0 0.1 1.4 7.6 0.0 2.6 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 EMC85421.1 - 0.019 14.5 0.7 1.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EMC85421.1 - 0.022 14.4 2.4 3.3 7.4 0.1 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EMC85421.1 - 0.039 13.3 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EMC85421.1 - 0.064 12.7 6.1 0.55 9.6 0.0 3.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EMC85421.1 - 0.071 12.6 0.9 12 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EMC85421.1 - 0.26 11.5 10.1 1.9 8.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain CutC PF03932.9 EMC85422.1 - 1.6e-57 194.0 0.0 3.3e-57 193.0 0.0 1.4 2 0 0 2 2 2 1 CutC family TMP-TENI PF02581.12 EMC85422.1 - 0.088 11.9 0.1 0.15 11.1 0.0 1.6 1 1 0 1 1 1 0 Thiamine monophosphate synthase/TENI COX15-CtaA PF02628.10 EMC85423.1 - 1.2e-85 287.0 5.5 1.4e-85 286.8 3.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein ATP_synt_H PF05493.8 EMC85424.1 - 4.2e-25 87.5 3.4 5.2e-25 87.2 2.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF2232 PF09991.4 EMC85424.1 - 0.0031 16.5 1.0 0.0034 16.4 0.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) GDA1_CD39 PF01150.12 EMC85425.1 - 1.1e-85 287.7 0.0 1.5e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Mito_carr PF00153.22 EMC85426.1 - 3.6e-54 180.4 1.5 1.6e-20 72.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein NDUF_B6 PF09782.4 EMC85426.1 - 0.1 12.4 1.0 0.23 11.3 0.0 2.0 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Aminotran_1_2 PF00155.16 EMC85428.1 - 1.9e-83 280.4 0.0 2.3e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CBS PF00571.23 EMC85429.1 - 8.6e-06 25.4 0.1 0.00044 19.9 0.0 2.4 2 0 0 2 2 2 1 CBS domain cNMP_binding PF00027.24 EMC85429.1 - 0.059 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Amino_oxidase PF01593.19 EMC85431.1 - 0.00028 20.1 2.2 0.058 12.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GDI PF00996.13 EMC85431.1 - 0.0035 15.7 0.0 0.0049 15.2 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 EMC85431.1 - 0.037 12.9 2.5 0.057 12.3 1.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase SRCR PF00530.13 EMC85432.1 - 1.3e-96 317.3 31.8 2.2e-29 101.7 1.5 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC85432.1 - 2.1e-21 75.9 17.7 3.4e-05 24.0 0.1 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 EMC85432.1 - 3.4e-06 27.2 3.0 0.017 15.3 0.1 4.0 4 0 0 4 4 4 1 Hepsin, SRCR YecR PF13992.1 EMC85432.1 - 0.015 15.4 5.5 2.7 8.2 0.1 3.9 4 0 0 4 4 4 0 YecR-like lipoprotein Phage_30_3 PF08010.6 EMC85432.1 - 0.2 11.1 0.4 42 3.6 0.0 3.3 3 1 1 4 4 4 0 Bacteriophage protein GP30.3 Lysyl_oxidase PF01186.12 EMC85433.1 - 4.7e-71 238.6 4.4 5.8e-71 238.3 3.0 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.6 EMC85433.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 CARDB DNA_ligase_A_M PF01068.16 EMC85433.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 ATP dependent DNA ligase domain Y_Y_Y PF07495.8 EMC85433.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain DUF2414 PF10309.4 EMC85435.1 - 0.00043 19.9 0.0 0.00072 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EMC85435.1 - 0.0008 19.3 0.1 0.0017 18.3 0.1 1.5 1 1 0 1 1 1 1 RNA binding domain VCBS PF13517.1 EMC85436.1 - 6.6e-32 109.6 10.5 2.3e-11 43.8 1.1 4.9 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EMC85436.1 - 9.4e-18 63.3 18.7 1.5e-05 24.5 0.2 5.7 5 0 0 5 5 5 4 FG-GAP repeat UnbV_ASPIC PF07593.7 EMC85436.1 - 2.1e-13 49.7 0.0 5.3e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 ASPIC and UnbV EGF_CA PF07645.10 EMC85436.1 - 1.6e-10 40.8 7.8 1.6e-10 40.8 5.4 1.8 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 EMC85436.1 - 0.0018 17.8 11.8 0.069 12.7 2.7 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like TcdB_toxin_midN PF12256.3 EMC85436.1 - 0.026 13.9 2.4 4.8 6.6 0.0 3.9 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Imm49 PF15660.1 EMC85436.1 - 0.14 12.2 0.3 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 49 Erf4 PF10256.4 EMC85437.1 - 9.1e-33 112.6 0.0 1.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3920 PF13058.1 EMC85437.1 - 0.063 13.0 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) NTR PF01759.16 EMC85438.1 - 1.2e-16 60.1 0.1 1.5e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.12 EMC85438.1 - 0.0019 17.7 0.1 0.0024 17.4 0.1 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase PI3_PI4_kinase PF00454.22 EMC85439.1 - 1.5e-54 184.9 0.0 1.9e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MORN PF02493.15 EMC85440.1 - 1.3e-27 93.8 21.5 3.1e-08 32.8 0.2 5.6 6 0 0 6 6 6 4 MORN repeat HCBP_related PF06594.6 EMC85440.1 - 0.00011 21.7 1.1 0.095 12.3 0.0 3.2 3 0 0 3 3 3 2 Haemolysin-type calcium binding protein related domain DHDPS PF00701.17 EMC85441.1 - 5.1e-55 186.1 0.0 5.6e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ank PF00023.25 EMC85442.1 - 7.8e-07 28.5 0.0 1.8e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EMC85442.1 - 9.8e-07 29.1 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC85442.1 - 1.5e-06 28.4 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC85442.1 - 8.9e-06 25.7 0.0 0.0072 16.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC85442.1 - 8.2e-05 22.4 0.0 0.0018 18.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat ubiquitin PF00240.18 EMC85443.1 - 2.2e-15 55.8 0.1 3.3e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC85443.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MMS19_N PF14500.1 EMC85444.1 - 1.2e-97 326.2 3.2 3.9e-97 324.6 0.1 3.0 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EMC85444.1 - 3.8e-93 312.4 20.4 4.2e-53 180.5 0.0 5.0 3 2 1 4 4 4 3 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EMC85444.1 - 2.2e-09 37.4 10.8 0.0057 16.8 0.4 6.5 4 2 2 6 6 6 4 HEAT repeats MIF4G PF02854.14 EMC85444.1 - 0.013 14.9 0.1 0.091 12.1 0.0 2.3 2 0 0 2 2 2 0 MIF4G domain RhoGAP PF00620.22 EMC85444.1 - 0.023 14.2 1.2 0.2 11.2 0.0 3.0 3 0 0 3 3 3 0 RhoGAP domain TAFH PF07531.9 EMC85444.1 - 0.71 9.5 7.3 0.42 10.2 0.0 3.9 4 1 1 5 5 5 0 NHR1 homology to TAF His_Phos_1 PF00300.17 EMC85445.1 - 7.9e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KRTDAP PF15200.1 EMC85445.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte differentiation-associated RhoGAP PF00620.22 EMC85446.1 - 1.2e-35 122.4 0.4 1.2e-35 122.4 0.3 1.8 2 0 0 2 2 2 1 RhoGAP domain HTH_psq PF05225.11 EMC85448.1 - 2.3e-15 55.8 0.3 1.3e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain LIM_bind PF01803.11 EMC85449.1 - 6.5e-35 120.3 2.1 6.5e-35 120.3 1.4 2.0 2 1 0 2 2 2 1 LIM-domain binding protein Prominin PF05478.6 EMC85450.1 - 5.4e-128 427.7 2.5 6.6e-128 427.4 1.7 1.0 1 0 0 1 1 1 1 Prominin Spc7 PF08317.6 EMC85450.1 - 0.013 14.1 1.8 0.019 13.6 1.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.6 EMC85450.1 - 0.03 14.1 0.7 0.11 12.3 0.5 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Flagellar_rod PF05149.7 EMC85450.1 - 0.1 11.7 0.9 0.19 10.8 0.6 1.4 1 1 0 1 1 1 0 Paraflagellar rod protein Fib_alpha PF08702.5 EMC85450.1 - 0.11 12.6 0.2 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MMR_HSR1 PF01926.18 EMC85450.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase GrpE PF01025.14 EMC85450.1 - 0.2 11.1 3.0 0.52 9.8 2.1 1.7 1 1 0 1 1 1 0 GrpE Baculo_PEP_C PF04513.7 EMC85450.1 - 1.7 8.4 6.6 1.1 9.0 2.0 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1741 PF08427.5 EMC85451.1 - 1.1e-86 290.1 5.6 1.1e-86 290.1 3.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) EF-hand_7 PF13499.1 EMC85452.1 - 2.6e-23 81.9 1.5 5.4e-15 55.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC85452.1 - 7.1e-22 75.0 9.1 2.3e-07 29.5 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC85452.1 - 8e-19 65.7 4.7 5.9e-06 25.7 0.0 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EMC85452.1 - 4.4e-17 60.5 3.2 4.8e-05 22.5 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EMC85452.1 - 3.1e-15 55.5 7.6 1.1e-07 31.3 0.2 3.7 3 2 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC85452.1 - 3.6e-06 26.9 1.7 0.00014 21.8 0.2 3.0 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC85452.1 - 0.0002 21.0 2.1 0.039 13.6 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand S10_plectin PF03501.10 EMC85452.1 - 0.027 14.3 0.0 0.086 12.7 0.0 1.9 1 1 0 1 1 1 0 Plectin/S10 domain EF-hand_9 PF14658.1 EMC85452.1 - 0.03 14.2 0.2 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain EF-hand_2 PF09068.6 EMC85452.1 - 0.17 11.9 2.3 20 5.2 0.0 3.0 2 1 0 3 3 3 0 EF hand NAGidase PF07555.8 EMC85454.1 - 1.5e-95 319.6 0.0 2.5e-95 318.9 0.0 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Acetyltransf_1 PF00583.19 EMC85454.1 - 0.064 13.2 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Nucleoplasmin PF03066.10 EMC85455.1 - 1.5e-45 154.3 0.0 1.6e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoplasmin Nitrophorin PF02087.10 EMC85455.1 - 0.0015 18.3 0.1 0.002 17.9 0.1 1.2 1 0 0 1 1 1 1 Nitrophorin FGF PF00167.13 EMC85456.1 - 1e-38 131.8 1.0 1.7e-38 131.1 0.7 1.3 1 0 0 1 1 1 1 Fibroblast growth factor DPCD PF14913.1 EMC85457.1 - 6.4e-85 283.1 0.2 7.4e-85 282.9 0.2 1.0 1 0 0 1 1 1 1 DPCD protein family DUF2914 PF11141.3 EMC85457.1 - 0.013 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) MucBP PF06458.7 EMC85457.1 - 0.055 14.0 1.0 0.5 11.0 0.1 2.2 2 0 0 2 2 2 0 MucBP domain Sugar_tr PF00083.19 EMC85460.1 - 1.1e-100 337.3 25.4 1.2e-100 337.2 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC85460.1 - 2.3e-17 62.7 52.6 2e-16 59.6 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gate PF07670.9 EMC85460.1 - 6.3 6.7 17.8 1.1 9.1 0.4 3.4 2 2 1 3 3 3 0 Nucleoside recognition WD40 PF00400.27 EMC85461.1 - 1.1e-59 196.3 16.0 4e-10 39.1 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 EMC85461.1 - 3.9e-27 93.5 3.8 6.9e-27 92.7 2.7 1.4 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 EMC85461.1 - 1.1e-10 41.0 0.5 3.3e-10 39.5 0.1 2.0 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 EMC85461.1 - 5.8e-08 32.1 0.0 1.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EMC85461.1 - 1.5e-06 27.2 1.8 0.049 12.3 0.0 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EMC85461.1 - 0.00069 17.8 9.1 0.93 7.5 0.1 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 DUF4508 PF14969.1 EMC85461.1 - 0.022 14.7 0.1 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Cellulase-like PF12876.2 EMC85461.1 - 0.092 13.2 0.0 0.79 10.2 0.0 2.6 3 0 0 3 3 3 0 Sugar-binding cellulase-like I-set PF07679.11 EMC85462.1 - 3e-14 52.6 0.0 4.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC85462.1 - 6.4e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.16 EMC85462.1 - 1e-06 28.6 0.3 1e-06 28.6 0.2 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain ig PF00047.20 EMC85462.1 - 7.7e-06 25.9 0.0 3.3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.13 EMC85462.1 - 0.00013 22.4 20.3 0.00013 22.4 14.1 2.0 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_2 PF07648.10 EMC85462.1 - 0.00019 21.2 1.1 0.00019 21.2 0.8 2.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.12 EMC85462.1 - 0.0007 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC85462.1 - 0.01 16.2 0.0 0.032 14.7 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin domain Mtc PF03820.12 EMC85463.1 - 7.5e-142 471.4 0.0 8.4e-142 471.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PDZ PF00595.19 EMC85464.1 - 1.1e-36 124.8 1.0 1.8e-17 63.2 0.2 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC85464.1 - 4.5e-13 48.8 0.1 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 EMC85464.1 - 0.014 15.1 0.7 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 Tricorn protease PDZ domain AAA_25 PF13481.1 EMC85466.1 - 1.8e-15 56.8 0.0 3.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EMC85466.1 - 1.5e-07 30.7 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 EMC85466.1 - 7e-06 26.2 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC85466.1 - 0.0002 21.4 0.0 0.00055 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EMC85466.1 - 0.00024 20.5 0.0 0.00067 19.1 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EMC85466.1 - 0.00026 21.3 0.0 0.00051 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EMC85466.1 - 0.00038 19.4 0.0 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DnaB_C PF03796.10 EMC85466.1 - 0.0007 18.5 0.0 0.0016 17.4 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_33 PF13671.1 EMC85466.1 - 0.006 16.4 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC85466.1 - 0.0073 17.1 0.0 0.03 15.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EMC85466.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EMC85466.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EMC85466.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 EMC85466.1 - 0.069 12.5 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.1 EMC85466.1 - 0.082 12.8 0.1 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EMC85466.1 - 0.11 11.7 0.1 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 EMC85466.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EMC85466.1 - 0.12 12.6 0.1 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF1840 PF08895.6 EMC85466.1 - 0.12 12.3 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) cobW PF02492.14 EMC85466.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain L51_S25_CI-B8 PF05047.11 EMC85467.1 - 8.8e-09 34.9 0.0 2.3e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PaaB PF06243.6 EMC85467.1 - 0.082 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Phenylacetic acid degradation B rve_3 PF13683.1 EMC85467.1 - 0.098 12.1 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain Sema PF01403.14 EMC85468.1 - 3.3e-117 391.6 0.0 4.4e-117 391.2 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 EMC85468.1 - 6.7e-06 26.1 6.2 2e-05 24.6 4.3 1.9 1 0 0 1 1 1 1 Plexin repeat Ig_2 PF13895.1 EMC85468.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Mito_fiss_reg PF05308.6 EMC85468.1 - 0.23 10.8 1.5 0.39 10.0 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator FAM178 PF14816.1 EMC85469.1 - 5.9e-164 545.2 5.6 7.3e-164 544.9 3.9 1.1 1 0 0 1 1 1 1 Family of unknown function, FAM178 Sox_N PF12444.3 EMC85471.1 - 9.4e-06 26.6 0.0 5.1e+02 1.8 0.0 9.0 11 0 0 11 11 11 0 Sox developmental protein N terminal Tom5 PF10642.4 EMC85471.1 - 3.4e-05 23.3 2.3 52 3.5 0.0 6.3 5 1 2 7 7 7 0 Mitochondrial import receptor subunit or translocase ISAV_HA PF06215.6 EMC85471.1 - 0.018 13.3 10.4 0.34 9.1 0.6 3.3 1 1 2 3 3 3 0 Infectious salmon anaemia virus haemagglutinin RRM_DME PF15628.1 EMC85471.1 - 0.19 11.4 0.7 2.6e+02 1.3 0.0 4.1 2 2 3 5 5 5 0 RRM in Demeter HNOBA PF07701.9 EMC85471.1 - 0.82 8.8 3.4 63 2.6 0.1 3.5 1 1 3 4 4 4 0 Heme NO binding associated DUF645 PF04875.7 EMC85471.1 - 4.4 7.0 26.6 10 5.8 0.2 5.6 2 2 3 5 5 5 0 Protein of unknown function, DUF645 Dynamin_M PF01031.15 EMC85472.1 - 3.8e-69 232.7 4.7 8.5e-69 231.5 0.7 3.0 3 1 1 4 4 4 1 Dynamin central region Dynamin_N PF00350.18 EMC85472.1 - 3.2e-42 144.1 0.0 8.4e-42 142.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EMC85472.1 - 4e-25 87.5 3.2 1e-24 86.2 2.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 EMC85472.1 - 1.4e-07 31.6 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Bunya_NS-S PF01104.12 EMC85474.1 - 0.0083 15.5 8.0 7.7 6.0 0.5 6.0 1 1 5 6 6 6 4 Bunyavirus non-structural protein NS-s Vinculin PF01044.14 EMC85475.1 - 1.1e-22 80.0 1.6 1.2e-22 79.8 1.1 1.0 1 0 0 1 1 1 1 Vinculin family Laminin_EGF PF00053.19 EMC85476.1 - 1.3e-40 137.0 99.7 7.5e-10 38.5 11.4 5.3 4 1 1 5 5 5 5 Laminin EGF-like (Domains III and V) cEGF PF12662.2 EMC85476.1 - 0.024 14.2 1.8 0.024 14.2 1.2 9.1 8 1 0 8 8 8 0 Complement Clr-like EGF-like hEGF PF12661.2 EMC85476.1 - 0.034 14.2 2.4 0.034 14.2 1.7 9.4 12 0 0 12 12 12 0 Human growth factor-like EGF TMEM154 PF15102.1 EMC85476.1 - 0.065 12.9 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF3753 PF12575.3 EMC85476.1 - 0.2 11.5 2.1 0.32 10.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Microtub_assoc PF07989.6 EMC85477.1 - 8.3e-29 99.2 8.1 8.3e-29 99.2 5.6 9.0 8 2 5 13 13 13 2 Microtubule associated Desmo_N PF06771.6 EMC85477.1 - 2.7 7.9 11.2 0.7 9.8 0.2 4.1 3 0 0 3 3 3 0 Viral Desmoplakin N-terminus MutS_IV PF05190.13 EMC85478.1 - 0.12 12.5 1.4 5 7.3 0.0 2.4 2 0 0 2 2 2 0 MutS family domain IV Tnp_P_element PF12017.3 EMC85478.1 - 0.21 10.8 3.5 0.28 10.4 0.3 2.2 2 1 1 3 3 3 0 Transposase protein TMF_DNA_bd PF12329.3 EMC85478.1 - 0.58 10.0 7.2 0.54 10.0 3.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MACPF PF01823.14 EMC85479.1 - 1.4e-06 28.1 1.7 1.7e-06 27.8 0.0 2.1 3 0 0 3 3 3 1 MAC/Perforin domain LRR_8 PF13855.1 EMC85480.1 - 1.3e-52 175.3 53.8 3.7e-13 49.0 2.1 9.2 5 2 5 10 10 10 9 Leucine rich repeat TIR PF01582.15 EMC85480.1 - 1.4e-28 99.1 0.0 2.8e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 EMC85480.1 - 3e-25 87.3 46.7 1.4e-06 27.7 1.0 10.3 4 3 9 13 13 13 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC85480.1 - 4.5e-14 50.3 53.8 0.34 11.1 0.1 15.4 15 2 0 15 15 15 8 Leucine Rich Repeat TIR_2 PF13676.1 EMC85480.1 - 3.5e-09 36.7 0.0 7.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 EMC85480.1 - 5e-07 29.1 54.2 0.11 12.6 0.5 13.4 13 2 2 15 15 15 6 Leucine Rich repeat LRR_9 PF14580.1 EMC85480.1 - 8.7e-06 25.4 12.8 0.088 12.3 0.5 4.5 4 1 1 5 5 5 3 Leucine-rich repeat LRR_7 PF13504.1 EMC85480.1 - 0.0011 18.7 47.3 3.3 8.3 0.1 13.8 16 0 0 16 16 16 1 Leucine rich repeat FXa_inhibition PF14670.1 EMC85481.1 - 6.6e-10 38.9 4.0 6.6e-10 38.9 2.8 4.3 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site MACPF PF01823.14 EMC85481.1 - 9.3e-07 28.7 0.8 2.3e-06 27.4 0.2 1.8 2 0 0 2 2 2 1 MAC/Perforin domain fn3 PF00041.16 EMC85481.1 - 0.0082 16.2 0.0 0.028 14.5 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain cEGF PF12662.2 EMC85481.1 - 2.3 7.9 10.7 0.29 10.8 0.5 3.4 3 0 0 3 3 3 0 Complement Clr-like EGF-like Laminin_G_3 PF13385.1 EMC85482.1 - 1.1e-25 90.6 0.1 2.1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sushi PF00084.15 EMC85482.1 - 1.1e-14 54.4 60.7 4.4e-07 30.1 3.3 9.4 8 3 0 8 8 8 4 Sushi domain (SCR repeat) Notch PF00066.12 EMC85482.1 - 2.1e-12 47.0 59.9 2.8e-07 30.6 2.1 5.9 6 0 0 6 6 4 3 LNR domain Peptidase_M43 PF05572.8 EMC85482.1 - 5.9e-09 35.6 0.1 1.9e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EMC85482.1 - 0.0038 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like fn3 PF00041.16 EMC85482.1 - 0.0041 17.2 1.9 3.3 7.8 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain Reprolysin_4 PF13583.1 EMC85482.1 - 0.0048 16.4 0.1 0.016 14.7 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC85482.1 - 0.014 15.4 0.1 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Laminin_G_2 PF02210.19 EMC85482.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Peptidase_M57 PF12388.3 EMC85482.1 - 0.11 11.7 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EMC85482.1 - 0.62 9.7 2.1 1.3 8.7 1.5 1.5 1 1 0 1 1 1 0 Matrixin fn3 PF00041.16 EMC85483.1 - 2.6e-206 668.4 34.7 2.5e-16 59.5 0.0 15.3 15 0 0 15 15 15 15 Fibronectin type III domain Fibrinogen_C PF00147.13 EMC85483.1 - 2.5e-83 279.3 7.6 3.9e-83 278.6 5.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.8 EMC85483.1 - 1.1e-55 185.4 257.2 8.5e-05 22.6 8.4 13.4 13 0 0 13 13 13 13 EGF-like domain hEGF PF12661.2 EMC85483.1 - 7.4e-27 91.5 113.3 0.013 15.5 1.2 14.3 13 0 0 13 13 13 13 Human growth factor-like EGF Interfer-bind PF09294.5 EMC85483.1 - 1e-13 51.2 0.0 0.51 10.4 0.0 8.6 9 1 1 10 10 10 3 Interferon-alpha/beta receptor, fibronectin type III EGF PF00008.22 EMC85483.1 - 1.6e-13 50.3 219.1 0.025 14.5 7.3 13.6 13 0 0 13 13 13 11 EGF-like domain Actin PF00022.14 EMC85483.1 - 0.057 11.8 4.2 58 1.9 0.0 5.4 4 1 1 5 5 5 0 Actin TNF PF00229.13 EMC85484.1 - 2.3e-19 69.2 0.1 4.1e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family MgtE PF01769.11 EMC85484.1 - 0.035 14.3 0.2 0.056 13.7 0.2 1.2 1 0 0 1 1 1 0 Divalent cation transporter TNF PF00229.13 EMC85485.1 - 4e-36 123.3 0.1 5.6e-36 122.8 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 EMC85485.1 - 0.071 13.1 0.3 0.2 11.6 0.2 1.9 1 1 0 1 1 1 0 C1q domain DUF4481 PF14800.1 EMC85486.1 - 1.7e-56 191.4 4.1 1.8e-56 191.2 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) CMV_US PF08001.6 EMC85486.1 - 0.23 10.5 1.5 0.29 10.1 1.0 1.1 1 0 0 1 1 1 0 CMV US Corona_7 PF02398.11 EMC85486.1 - 9 6.8 7.6 11 6.6 3.2 2.4 2 1 0 2 2 2 0 Coronavirus protein 7 V-ATPase_G PF03179.10 EMC85487.1 - 6.3e-25 87.5 6.4 7.6e-25 87.2 4.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_F6 PF05511.6 EMC85487.1 - 0.0031 17.3 0.3 0.0036 17.1 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 GA PF01468.12 EMC85487.1 - 0.09 12.9 2.1 0.16 12.1 1.5 1.5 1 0 0 1 1 1 0 GA module Frigida PF07899.6 EMC85487.1 - 1.1 7.9 5.6 1.1 7.9 3.6 1.3 1 1 0 1 1 1 0 Frigida-like protein Sds3 PF08598.6 EMC85487.1 - 2.5 7.5 8.1 1.7e+02 1.5 5.6 2.0 1 1 0 1 1 1 0 Sds3-like ATP-synt_B PF00430.13 EMC85487.1 - 5.9 6.7 10.7 10 5.9 7.4 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Sec1 PF00995.18 EMC85488.1 - 6.1e-151 503.8 0.7 6.9e-151 503.6 0.5 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.1 EMC85488.1 - 0.009 16.0 0.8 0.028 14.4 0.5 1.8 1 0 0 1 1 1 1 Putative coat protein Rapamycin_bind PF08771.6 EMC85488.1 - 0.025 14.6 0.5 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 Rapamycin binding domain Ctr PF04145.10 EMC85490.1 - 2.3e-20 73.0 1.7 2.9e-20 72.8 1.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Glyco_transf_43 PF03360.11 EMC85491.1 - 1.7e-30 106.1 0.0 1.9e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 DUF1593 PF07632.6 EMC85492.1 - 0.21 10.8 0.9 32 3.7 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1593) NUMOD1 PF07453.8 EMC85492.1 - 4.2 7.3 22.5 53 3.8 0.1 8.0 6 4 0 6 6 6 0 NUMOD1 domain DUF656 PF04920.7 EMC85492.1 - 5.9 6.6 11.7 31 4.2 0.3 3.9 1 1 3 4 4 4 0 Family of unknown function (DUF656) 7tm_1 PF00001.16 EMC85496.1 - 1.8e-38 132.1 17.5 2.2e-38 131.9 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) T2SF PF00482.18 EMC85496.1 - 2.6 7.9 4.9 13 5.7 0.1 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF3548 PF12068.3 EMC85497.1 - 0.066 12.4 6.7 22 4.2 0.1 4.1 1 1 4 5 5 5 0 Domain of unknown function (DUF3548) zf-CCCH PF00642.19 EMC85498.1 - 4e-09 35.9 17.2 0.00024 20.7 0.7 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1540 PF07561.6 EMC85498.1 - 0.53 10.3 4.3 22 5.1 0.1 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1540) 7tm_1 PF00001.16 EMC85499.1 - 4.8e-47 160.2 20.8 8.2e-47 159.4 14.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TrbE PF11100.3 EMC85499.1 - 0.73 9.7 12.4 0.034 14.0 3.5 2.6 2 1 0 2 2 2 0 Conjugal transfer protein TrbE RhoGEF PF00621.15 EMC85500.1 - 1.9e-37 128.8 8.5 3.2e-37 128.1 5.9 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 EMC85500.1 - 2.5e-11 42.7 0.0 7.2e-11 41.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC85500.1 - 7.1e-11 41.5 0.1 1.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC85500.1 - 5.2e-10 38.6 0.0 1.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC85500.1 - 0.018 15.2 2.8 0.026 14.7 0.0 2.6 3 1 0 3 3 3 0 PH domain GLTT PF01744.15 EMC85501.1 - 0.00015 21.1 2.5 0.44 9.9 0.4 3.3 1 1 1 3 3 3 2 GLTT repeat (6 copies) Lamprin PF06403.6 EMC85501.1 - 0.001 18.8 1.8 0.14 11.9 0.5 2.1 1 1 1 2 2 2 2 Lamprin Sporozoite_P67 PF05642.6 EMC85501.1 - 0.1 10.4 1.3 0.18 9.6 0.9 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Glutenin_hmw PF03157.8 EMC85501.1 - 0.26 9.5 2.4 0.46 8.6 1.7 1.5 1 1 0 1 1 1 0 High molecular weight glutenin subunit Peptidase_M13_N PF05649.8 EMC85502.1 - 1.1e-132 442.7 1.8 1.1e-132 442.7 1.2 1.5 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 EMC85502.1 - 3.7e-64 215.7 0.6 1.2e-63 214.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_MA_2 PF13485.1 EMC85502.1 - 0.039 13.9 0.0 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 Peptidase MA superfamily Fib_alpha PF08702.5 EMC85502.1 - 0.17 12.0 3.4 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PI-PLC-X PF00388.14 EMC85503.1 - 4.3e-63 211.0 0.0 8.9e-63 210.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMC85503.1 - 9.8e-42 141.6 0.4 2.4e-41 140.3 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC85503.1 - 8.3e-25 86.6 2.6 1.8e-24 85.5 0.2 2.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EMC85503.1 - 4.4e-16 58.4 0.0 1.1e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 EMC85503.1 - 8e-12 45.1 1.8 1.1e-10 41.4 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC85503.1 - 2.8e-09 35.6 2.6 4.4e-05 22.4 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 EMC85503.1 - 5.5e-07 29.1 4.9 4.5e-06 26.2 0.1 3.7 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 EMC85503.1 - 1e-06 28.1 0.9 0.039 13.8 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EMC85503.1 - 3.2e-05 23.0 4.9 0.00037 19.7 0.0 3.0 3 1 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EMC85503.1 - 0.0001 21.8 0.6 0.11 12.0 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC85503.1 - 0.0018 18.2 0.2 0.0055 16.7 0.1 1.8 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Mcp5_PH PF12814.2 EMC85503.1 - 0.0069 16.2 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 EMC85503.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 PH domain EF-hand_4 PF12763.2 EMC85503.1 - 0.025 14.2 0.1 0.085 12.6 0.1 1.9 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SNase PF00565.12 EMC85504.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal nuclease homologue Acatn PF13000.2 EMC85505.1 - 5e-100 335.6 16.6 2.9e-57 194.4 4.9 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Aldo_ket_red PF00248.16 EMC85507.1 - 2.3e-30 105.3 0.0 3e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Telomere_Sde2_2 PF13297.1 EMC85507.1 - 0.29 10.4 1.7 0.63 9.3 0.2 2.0 2 0 0 2 2 2 0 Telomere stability C-terminal Aldo_ket_red PF00248.16 EMC85508.1 - 2.3e-15 56.1 0.0 2.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PARP PF00644.15 EMC85509.1 - 3e-34 118.2 4.0 2.7e-33 115.1 2.8 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 EMC85509.1 - 3.7e-09 35.8 7.5 5.8e-06 25.6 0.7 2.7 2 0 0 2 2 2 2 WWE domain zf-CCCH PF00642.19 EMC85509.1 - 0.0078 15.8 0.1 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tropomyosin_1 PF12718.2 EMC85510.1 - 0.0046 16.7 34.9 0.047 13.5 9.4 2.2 2 0 0 2 2 2 2 Tropomyosin like CENP-F_leu_zip PF10473.4 EMC85510.1 - 0.012 15.4 14.1 0.012 15.4 9.8 3.2 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EMC85510.1 - 0.015 13.7 30.8 0.14 10.6 8.4 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light IncA PF04156.9 EMC85510.1 - 0.034 13.7 37.9 0.36 10.3 10.3 2.9 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 EMC85510.1 - 0.036 13.0 32.9 0.013 14.5 9.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 EMC85510.1 - 0.051 12.0 25.2 0.022 13.2 15.3 1.7 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.6 EMC85510.1 - 0.21 10.2 28.9 0.16 10.6 6.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EMC85510.1 - 0.4 10.9 15.1 0.69 10.2 0.0 4.2 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EMC85510.1 - 0.4 9.8 35.3 0.42 9.7 9.3 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 EMC85510.1 - 0.49 8.8 22.1 0.17 10.3 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DASH_Hsk3 PF08227.6 EMC85510.1 - 1.1 9.4 7.3 0.4 10.9 0.8 3.0 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like ADIP PF11559.3 EMC85510.1 - 2.9 7.7 30.3 1.7 8.5 5.2 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EMC85510.1 - 3.6 6.6 8.0 6.9 5.7 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CemA PF03040.9 EMC85511.1 - 0.0038 16.8 6.0 0.0038 16.8 4.2 2.4 2 1 1 3 3 3 1 CemA family DUF4094 PF13334.1 EMC85511.1 - 0.062 13.6 0.6 0.062 13.6 0.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) Macoilin PF09726.4 EMC85511.1 - 0.088 11.0 41.0 0.0096 14.2 12.1 2.1 2 0 0 2 2 2 0 Transmembrane protein V_ATPase_I PF01496.14 EMC85511.1 - 8.3 4.1 27.4 1 7.1 7.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PH PF00169.24 EMC85512.1 - 2e-09 37.6 0.3 2e-09 37.6 0.2 2.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EMC85512.1 - 8.9e-07 29.1 2.9 2.3e-05 24.5 2.1 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain SpoIIAA-like PF11964.3 EMC85512.1 - 0.028 14.7 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 SpoIIAA-like PH_3 PF14593.1 EMC85512.1 - 0.041 13.7 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 PH domain PH_9 PF15410.1 EMC85512.1 - 0.056 13.6 0.5 0.15 12.1 0.3 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Pentaxin PF00354.12 EMC85513.1 - 1.6e-27 96.1 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 EMC85513.1 - 8.4e-14 52.0 0.0 1.3e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF438 PF04282.8 EMC85513.1 - 0.035 13.8 0.7 0.073 12.8 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF438) PQ-loop PF04193.9 EMC85514.1 - 1.2e-06 27.9 0.2 1.9e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 PQ loop repeat PPR_1 PF12854.2 EMC85514.1 - 0.025 14.0 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 PPR repeat DUF3278 PF11683.3 EMC85514.1 - 0.047 13.6 0.5 0.051 13.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) PQ-loop PF04193.9 EMC85515.1 - 7.1e-18 63.9 0.7 7.1e-18 63.9 0.5 2.1 3 0 0 3 3 3 1 PQ loop repeat MtN3_slv PF03083.11 EMC85515.1 - 0.041 13.7 0.5 0.41 10.5 0.1 2.5 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF2427 PF10348.4 EMC85515.1 - 0.061 12.9 0.3 0.19 11.3 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Homeobox PF00046.24 EMC85516.1 - 3e-12 45.9 0.5 4.2e-12 45.4 0.4 1.2 1 0 0 1 1 1 1 Homeobox domain Pro_CA PF00484.14 EMC85517.1 - 0.0029 17.6 0.9 0.0066 16.4 0.7 1.6 1 0 0 1 1 1 1 Carbonic anhydrase Mlf1IP PF10248.4 EMC85518.1 - 5.7e-76 254.0 8.3 3.4e-75 251.4 5.8 1.8 1 1 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Filo_VP35 PF02097.10 EMC85518.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 1 0 1 1 1 0 Filoviridae VP35 GTP_EFTU PF00009.22 EMC85519.1 - 1.1e-61 207.6 0.0 1.6e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMC85519.1 - 9.9e-33 112.2 0.2 2.9e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 EMC85519.1 - 1.1e-29 102.0 0.0 2.6e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EMC85519.1 - 1.6e-24 85.5 0.0 3.6e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMC85519.1 - 8.6e-16 57.8 0.0 2.2e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC85519.1 - 0.0054 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMC85519.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.5 EMC85519.1 - 0.11 11.6 0.0 0.4 9.8 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Latexin PF06907.7 EMC85520.1 - 6.9e-44 149.6 0.0 7.6e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Latexin Latexin PF06907.7 EMC85521.1 - 5e-74 248.1 0.1 5.6e-74 248.0 0.1 1.0 1 0 0 1 1 1 1 Latexin DUF3336 PF11815.3 EMC85521.1 - 0.086 12.3 0.4 0.19 11.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3336) MFS_1 PF07690.11 EMC85522.1 - 1.9e-39 135.4 65.4 6.1e-28 97.5 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC85522.1 - 1.2e-05 23.9 19.1 1.2e-05 23.9 13.2 3.0 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 EMC85522.1 - 0.14 12.0 6.4 0.099 12.4 1.4 3.0 3 0 0 3 3 3 0 MFS_1 like family Sugar_tr PF00083.19 EMC85522.1 - 0.5 8.8 39.4 1.4 7.3 27.3 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter IQ-like PF15157.1 EMC85523.1 - 2.5e-44 149.4 2.9 2.7e-44 149.2 2.0 1.0 1 0 0 1 1 1 1 IQ-like IQ PF00612.22 EMC85523.1 - 0.021 14.4 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fmp27_WPPW PF10359.4 EMC85523.1 - 0.056 11.8 2.3 0.063 11.6 1.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2205 PF10224.4 EMC85523.1 - 0.095 12.2 3.2 0.14 11.7 1.9 1.6 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 EMC85523.1 - 1.9 8.0 4.8 2.2 7.8 3.3 1.1 1 0 0 1 1 1 0 IncA protein SCHIP-1 PF10148.4 EMC85524.1 - 1.7e-123 410.5 16.2 1.9e-123 410.4 11.3 1.0 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 FEZ PF07763.8 EMC85524.1 - 0.00012 21.8 7.7 0.00021 21.0 5.1 1.6 1 1 0 1 1 1 1 FEZ-like protein FAM117 PF15388.1 EMC85524.1 - 0.81 8.8 7.2 1.8 7.7 5.0 1.5 1 1 0 1 1 1 0 Protein Family FAM117 FIIND PF13553.1 EMC85525.1 - 8.7e-23 81.0 0.0 9.6e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Function to find WD40 PF00400.27 EMC85526.1 - 7.5e-13 47.8 3.1 7.2e-05 22.5 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EMC85526.1 - 3e-08 33.3 8.4 3e-08 33.3 5.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.19 EMC85526.1 - 9e-08 31.8 1.3 9e-08 31.8 0.9 2.8 3 0 0 3 3 2 1 B-box zinc finger zf-C3HC4_2 PF13923.1 EMC85526.1 - 3.7e-07 30.0 8.7 3.7e-07 30.0 6.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC85526.1 - 5.3e-07 29.1 4.7 5.3e-07 29.1 3.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC85526.1 - 1.1e-06 28.2 5.9 1.1e-06 28.2 4.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC85526.1 - 1.3e-06 27.9 6.7 1.3e-06 27.9 4.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC85526.1 - 3.7e-06 26.7 5.8 3.7e-06 26.7 4.0 2.8 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC85526.1 - 1.6e-05 24.5 4.3 1.6e-05 24.5 3.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger DUF349 PF03993.7 EMC85526.1 - 0.00097 19.2 0.4 0.003 17.6 0.3 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) U-box PF04564.10 EMC85526.1 - 0.024 14.5 0.1 0.096 12.6 0.0 2.1 1 1 0 1 1 1 0 U-box domain zf-RING_6 PF14835.1 EMC85526.1 - 0.06 13.1 5.4 0.023 14.4 1.5 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EMC85526.1 - 3.7 7.1 6.8 0.93 9.0 1.5 2.5 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 Arm PF00514.18 EMC85527.1 - 5.9e-89 289.2 20.8 9.4e-14 50.6 0.2 9.8 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC85527.1 - 2.6e-25 88.5 0.0 1.8e-08 34.5 0.0 5.7 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 EMC85527.1 - 2.6e-19 67.5 4.9 0.0014 18.5 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.15 EMC85527.1 - 8.1e-19 67.5 1.7 1.5e-18 66.7 1.2 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EMC85527.1 - 1.3e-16 60.4 5.2 2.1e-06 28.0 0.0 6.3 3 3 5 8 8 8 5 HEAT-like repeat Adaptin_N PF01602.15 EMC85527.1 - 7.1e-08 31.2 2.1 4e-07 28.7 1.5 2.2 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.8 EMC85527.1 - 1.3e-06 27.6 1.1 0.055 12.5 0.2 3.5 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.3 EMC85527.1 - 5.5e-06 26.3 0.6 1.1 9.2 0.1 4.3 4 1 1 5 5 5 3 V-ATPase subunit H V-ATPase_H_N PF03224.9 EMC85527.1 - 3.5e-05 23.0 0.9 0.001 18.2 0.2 2.6 1 1 0 2 2 2 1 V-ATPase subunit H Atx10homo_assoc PF09759.4 EMC85527.1 - 0.00038 20.1 0.2 5.6 6.7 0.1 4.3 2 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.4 EMC85527.1 - 0.0056 15.0 0.9 0.19 9.9 0.1 3.1 2 2 1 3 3 3 1 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 EMC85527.1 - 0.023 13.7 0.1 0.079 11.9 0.0 1.9 1 1 0 1 1 1 0 Mo25-like Cnd3 PF12719.2 EMC85527.1 - 0.044 12.7 0.2 5.2 5.9 0.0 3.7 2 2 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain RasGEF_N_2 PF14663.1 EMC85527.1 - 0.066 13.1 0.2 1 9.3 0.0 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1981 PF09324.5 EMC85527.1 - 0.096 12.2 0.3 1.6 8.2 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) CTNNBL PF08216.6 EMC85527.1 - 0.12 11.9 7.1 11 5.6 0.2 4.9 5 1 1 6 6 6 0 Catenin-beta-like, Arm-motif containing nuclear Arf PF00025.16 EMC85528.1 - 2e-56 189.9 0.0 2.4e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC85528.1 - 6.5e-14 51.4 1.5 3.3e-11 42.5 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMC85528.1 - 2e-12 46.7 0.0 2.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC85528.1 - 5.8e-11 42.9 0.0 8.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EMC85528.1 - 2.2e-08 33.5 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMC85528.1 - 1.6e-07 30.7 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC85528.1 - 9.4e-07 28.7 0.0 1.9e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC85528.1 - 2.4e-06 27.1 0.0 1.2e-05 24.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMC85528.1 - 0.0023 16.7 0.0 0.2 10.4 0.0 2.8 1 1 1 2 2 2 1 ArgK protein Thioredoxin_2 PF13098.1 EMC85528.1 - 0.0045 17.1 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Galactosyl_T PF01762.16 EMC85529.1 - 6.4e-57 192.3 0.0 8.6e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC85529.1 - 9.3e-06 25.0 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PP2C PF00481.16 EMC85530.1 - 1.5e-58 198.1 0.0 2.1e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMC85530.1 - 8.8e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMC85530.1 - 0.00031 20.4 0.0 0.0042 16.8 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF3317 PF11779.3 EMC85531.1 - 2.3e-12 46.1 10.1 2.9e-12 45.8 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2101 PF09874.4 EMC85531.1 - 0.16 11.4 2.6 0.18 11.2 1.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) NMD3 PF04981.8 EMC85532.1 - 1.4e-75 253.4 8.6 2.5e-75 252.6 6.0 1.4 1 0 0 1 1 1 1 NMD3 family TMEM37 PF15108.1 EMC85532.1 - 0.011 15.4 0.3 0.023 14.3 0.2 1.5 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF1289 PF06945.8 EMC85532.1 - 0.025 14.0 2.0 2.8 7.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DZR PF12773.2 EMC85532.1 - 0.039 13.7 8.0 0.18 11.6 4.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF3317 PF11779.3 EMC85533.1 - 4.3e-17 61.2 7.2 5.1e-17 61.0 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF4282 PF14110.1 EMC85533.1 - 0.023 14.8 0.7 0.029 14.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) ESSS PF10183.4 EMC85533.1 - 0.14 12.5 2.2 0.19 12.1 1.6 1.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2101 PF09874.4 EMC85533.1 - 0.77 9.2 5.9 0.88 9.0 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Collagen PF01391.13 EMC85534.1 - 3.2e-35 119.4 135.8 1.9e-08 33.6 21.6 5.1 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) C1q PF00386.16 EMC85534.1 - 4.4e-33 113.9 0.0 5.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 C1q domain DUF3421 PF11901.3 EMC85535.1 - 5.8e-16 58.3 0.1 8.3e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Mesd PF10185.4 EMC85535.1 - 0.082 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor zf-H2C2_2 PF13465.1 EMC85536.1 - 1.8e-45 151.0 39.9 1.3e-09 37.8 0.2 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC85536.1 - 2.1e-36 122.0 33.1 3.2e-07 30.2 1.1 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC85536.1 - 3.3e-25 86.5 31.4 1.5e-05 24.9 0.8 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC85536.1 - 1.3e-20 72.5 22.6 1.8e-05 24.4 0.4 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC85536.1 - 4.1e-18 64.9 8.3 0.0078 16.3 0.1 6.1 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC85536.1 - 1.9e-11 43.7 23.8 0.014 15.5 0.4 6.1 6 0 0 6 6 6 5 Zinc-finger of C2H2 type C1_4 PF07975.7 EMC85536.1 - 1.1e-05 25.2 12.3 0.011 15.6 1.1 4.4 1 1 5 6 6 6 4 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 EMC85536.1 - 1.3e-05 25.0 16.8 4.5 7.3 0.1 5.7 4 1 2 6 6 6 0 Zinc ribbon domain C1_1 PF00130.17 EMC85536.1 - 9.7e-05 22.0 6.7 1.6 8.5 0.1 4.3 1 1 5 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 EMC85536.1 - 0.0001 22.3 14.2 0.031 14.4 2.0 3.2 1 1 2 3 3 3 2 CHY zinc finger RRN7 PF11781.3 EMC85536.1 - 0.00097 18.5 10.3 16 5.1 0.1 5.9 6 0 0 6 6 6 0 RNA polymerase I-specific transcription initiation factor Rrn7 Evr1_Alr PF04777.8 EMC85536.1 - 0.0012 18.7 17.7 4.2 7.3 0.1 5.8 1 1 4 5 5 5 1 Erv1 / Alr family SprT-like PF10263.4 EMC85536.1 - 0.0018 17.9 13.5 0.17 11.5 1.7 3.6 1 1 3 4 4 4 3 SprT-like family DNA_RNApol_7kD PF03604.8 EMC85536.1 - 0.002 17.5 16.8 5.2 6.6 0.1 6.0 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2HC_2 PF13913.1 EMC85536.1 - 0.013 15.0 0.8 0.013 15.0 0.6 5.2 6 0 0 6 6 5 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EMC85536.1 - 0.04 14.0 18.9 0.52 10.4 0.0 4.2 2 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 EMC85536.1 - 0.067 12.8 12.3 10 5.9 0.1 5.6 6 0 0 6 6 6 0 XPA protein N-terminal BolA PF01722.13 EMC85536.1 - 0.086 12.8 0.6 4.6 7.2 0.0 2.8 2 1 1 3 3 3 0 BolA-like protein DrsE PF02635.10 EMC85536.1 - 0.14 12.2 0.5 15 5.6 0.0 3.1 2 2 1 3 3 3 0 DsrE/DsrF-like family Zn_ribbon_recom PF13408.1 EMC85536.1 - 0.15 12.3 17.7 5.2 7.4 1.4 4.2 3 1 1 4 4 4 0 Recombinase zinc beta ribbon domain FYVE PF01363.16 EMC85536.1 - 0.21 11.5 20.4 1.3 8.9 1.1 3.9 1 1 2 3 3 3 0 FYVE zinc finger DUF2688 PF10892.3 EMC85536.1 - 0.21 11.2 8.9 22 4.7 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2688) DUF678 PF05077.7 EMC85536.1 - 0.36 10.8 9.3 8.7 6.4 0.1 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF678) OSTMP1 PF09777.4 EMC85536.1 - 0.4 9.8 2.7 1.8 7.6 1.9 2.1 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Siva PF05458.7 EMC85536.1 - 0.79 9.2 8.1 0.18 11.3 1.4 2.4 1 1 1 2 2 2 0 Cd27 binding protein (Siva) DUF3133 PF11331.3 EMC85536.1 - 0.91 9.1 13.7 0.88 9.1 0.4 4.4 5 0 0 5 5 4 0 Protein of unknown function (DUF3133) FdhD-NarQ PF02634.10 EMC85536.1 - 1.1 8.6 4.2 17 4.7 0.3 2.9 1 1 2 3 3 3 0 FdhD/NarQ family Zn_Tnp_IS1595 PF12760.2 EMC85536.1 - 1.2 8.9 27.9 1.8 8.4 3.3 4.5 3 2 1 4 4 4 0 Transposase zinc-ribbon domain zf-LYAR PF08790.6 EMC85536.1 - 2.7 7.7 15.7 10 5.9 0.0 5.3 6 0 0 6 6 5 0 LYAR-type C2HC zinc finger Mu-like_Com PF10122.4 EMC85536.1 - 2.8 7.0 8.1 5.6 6.1 0.1 4.5 5 0 0 5 5 5 0 Mu-like prophage protein Com zf-C2H2_2 PF12756.2 EMC85536.1 - 3 8.0 16.6 15 5.7 0.5 5.1 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Yippee-Mis18 PF03226.9 EMC85536.1 - 5.8 7.0 9.5 3.5 7.7 0.3 3.2 2 2 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LIM PF00412.17 EMC85536.1 - 6.1 6.9 14.5 9 6.4 0.5 4.4 1 1 4 5 5 5 0 LIM domain Parecho_VpG PF06344.6 EMC85537.1 - 9.7e-12 44.6 0.0 1e+02 2.9 0.0 10.2 10 0 0 10 10 10 0 Parechovirus Genome-linked protein DUF1586 PF07625.6 EMC85537.1 - 4.4e-05 23.1 17.8 1.3e+02 2.5 0.0 9.9 10 0 0 10 10 10 0 Protein of unknown function (DUF1586) NMT1_2 PF13379.1 EMC85537.1 - 7.1e-05 22.3 20.6 21 4.4 0.1 8.6 1 1 9 10 10 10 6 NMT1-like family Gamma-thionin PF00304.15 EMC85537.1 - 0.011 15.7 43.7 26 4.9 0.3 10.0 1 1 9 10 10 10 0 Gamma-thionin family Axin_b-cat_bind PF08833.5 EMC85537.1 - 5.3 6.8 36.8 90 2.9 0.1 9.9 1 1 9 10 10 10 0 Axin beta-catenin binding domain TOH_N PF12549.3 EMC85538.1 - 0.00047 19.6 0.0 3.4 7.3 0.0 4.1 3 1 1 4 4 4 3 Tyrosine hydroxylase N terminal Crp PF00325.15 EMC85538.1 - 0.0099 15.3 0.2 63 3.1 0.0 4.6 6 0 0 6 6 6 3 Bacterial regulatory proteins, crp family Retro_M PF02813.9 EMC85539.1 - 4.6e-14 52.3 0.3 7.1e-14 51.7 0.2 1.3 1 0 0 1 1 1 1 Retroviral M domain GLTT PF01744.15 EMC85540.1 - 6.4e-07 28.6 30.9 0.001 18.4 0.8 5.1 3 1 3 6 6 6 6 GLTT repeat (6 copies) Neur_chan_LBD PF02931.18 EMC85541.1 - 7.9e-32 110.1 0.0 9.3e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC85541.1 - 3.2e-18 66.4 3.0 4.1e-18 66.1 2.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.17 EMC85544.1 - 5.6e-56 188.3 0.0 6.3e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC85544.1 - 1.1e-16 61.3 0.0 1.7e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC85544.1 - 2.5e-10 39.8 0.0 3.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC85544.1 - 0.0033 16.5 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC85544.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase SAM_2 PF07647.12 EMC85545.1 - 8.5e-09 35.1 0.3 4.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC85545.1 - 3.8e-05 23.7 0.1 3.8e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 EMC85545.1 - 0.031 14.2 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF4446 PF14584.1 EMC85545.1 - 0.033 13.9 1.0 0.033 13.9 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) APG6 PF04111.7 EMC85545.1 - 0.75 8.7 20.1 1.6 7.7 13.9 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 EMC85545.1 - 5.9 6.9 23.8 2.8 8.0 2.0 2.8 2 1 0 2 2 2 0 DivIVA protein Ribonuc_red_lgC PF02867.10 EMC85547.1 - 6.5e-223 741.1 0.0 7.6e-223 740.9 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EMC85547.1 - 4e-12 45.7 0.0 1.1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain 7tm_1 PF00001.16 EMC85548.1 - 9.1e-29 100.3 13.6 1.1e-28 100.0 9.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC85548.1 - 1.8e-27 95.8 5.7 1.8e-27 95.8 3.9 2.3 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 EMC85548.1 - 1e-08 34.6 12.3 2.1e-08 33.6 8.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 EMC85548.1 - 4.5e-05 22.8 8.8 7e-05 22.2 6.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.4 EMC85548.1 - 0.033 13.2 9.5 0.013 14.6 4.9 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4079 PF13301.1 EMC85548.1 - 0.76 9.7 5.3 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) 7tm_1 PF00001.16 EMC85549.1 - 3.9e-29 101.5 14.3 5.5e-29 101.0 9.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC85549.1 - 2.3e-20 72.8 5.7 2.3e-20 72.8 4.0 2.2 4 0 0 4 4 4 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 EMC85549.1 - 9e-11 41.4 9.6 1.1e-10 41.0 6.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 EMC85549.1 - 0.0019 17.5 6.8 0.0036 16.5 4.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.4 EMC85549.1 - 0.99 8.4 11.2 0.028 13.5 3.1 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 EMC85550.1 - 6.8e-28 97.2 10.0 6.8e-28 97.2 6.9 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC85550.1 - 7.2e-24 84.3 19.2 9.6e-24 83.8 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC85550.1 - 3.1e-05 23.2 14.8 4.8e-05 22.6 10.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC85550.1 - 0.44 9.6 16.1 0.85 8.6 11.2 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 EMC85551.1 - 7.2e-31 106.9 2.2 7.2e-31 106.9 1.5 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC85551.1 - 2.3e-20 72.8 9.7 3.4e-20 72.2 6.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC85551.1 - 1e-07 31.4 5.7 1.6e-07 30.7 4.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 EMC85552.1 - 4.5e-41 140.6 13.0 1.6e-22 79.8 4.7 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC85552.1 - 6.2e-17 61.6 13.8 2e-08 33.7 4.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 EMC85552.1 - 1e-06 28.2 21.9 0.00083 18.6 7.9 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srbc ATP_bind_1 PF03029.12 EMC85552.1 - 0.14 11.6 1.6 0.69 9.3 0.2 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 7tm_1 PF00001.16 EMC85553.1 - 1.3e-37 129.2 26.5 7.8e-21 74.3 9.9 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC85553.1 - 5.1e-21 74.9 22.5 4.3e-11 42.4 8.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 EMC85553.1 - 3.4e-07 29.8 28.0 0.0013 18.0 3.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srbc DUF4227 PF14004.1 EMC85553.1 - 0.14 11.9 1.8 0.52 10.1 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) 7tm_1 PF00001.16 EMC85554.1 - 2.6e-28 98.8 17.0 3e-28 98.6 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC85554.1 - 5.7e-26 91.0 12.0 5.7e-26 91.0 8.3 2.0 2 1 1 3 3 3 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 EMC85554.1 - 1.4e-10 40.7 15.0 2e-10 40.2 10.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC85554.1 - 0.004 16.3 8.3 0.004 16.3 5.8 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ubiquitin PF00240.18 EMC85555.1 - 4e-11 42.1 0.1 8e-11 41.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMC85555.1 - 0.00026 20.7 0.3 0.00088 19.0 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EMC85555.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EMC85555.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 EMC85555.1 - 2.6 7.5 16.0 0.4 10.1 0.4 5.0 4 1 0 4 4 4 0 XPC-binding domain 7tm_4 PF13853.1 EMC85556.1 - 1.3e-31 109.2 7.3 1.3e-31 109.2 5.0 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC85556.1 - 1.6e-30 106.1 17.7 2e-30 105.7 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC85556.1 - 2.8e-10 39.8 7.0 5.1e-10 38.9 4.8 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ribosomal_S17 PF00366.15 EMC85558.1 - 2.4e-31 107.5 2.0 3e-31 107.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.6 EMC85558.1 - 0.042 13.0 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Ribosomal_L19 PF01245.15 EMC85558.1 - 0.95 9.2 4.3 0.88 9.3 1.1 2.1 1 1 1 2 2 2 0 Ribosomal protein L19 PGM_PMM_III PF02880.11 EMC85559.1 - 4.2e-05 23.5 8.7 14 5.7 0.2 6.2 1 1 4 5 5 5 5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Cadherin PF00028.12 EMC85560.1 - 2.5e-84 277.6 1.3 1.1e-17 64.0 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC85560.1 - 1.3e-55 187.5 0.1 2.5e-55 186.5 0.1 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC85560.1 - 1.9e-05 24.1 0.0 0.47 10.0 0.0 3.7 3 0 0 3 3 3 3 Cadherin-like TSP_1 PF00090.14 EMC85561.1 - 5.6e-12 45.5 47.5 1.7e-06 28.0 3.9 4.6 4 2 0 4 4 4 3 Thrombospondin type 1 domain PLAC PF08686.6 EMC85561.1 - 6.1e-12 45.6 8.1 6.1e-12 45.6 5.6 3.1 4 0 0 4 4 4 1 PLAC (protease and lacunin) domain Pribosyltran PF00156.22 EMC85562.1 - 4e-06 26.5 0.0 3.1e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain RDM PF11002.3 EMC85562.1 - 0.096 12.3 0.2 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 RFPL defining motif (RDM) NUDIX PF00293.23 EMC85563.1 - 8.1e-13 48.1 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N_2 PF13602.1 EMC85564.1 - 3.6e-12 47.2 0.0 1e-11 45.8 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC85564.1 - 1e-09 38.1 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMC85564.1 - 1.7e-09 37.2 0.0 5.6e-09 35.6 0.0 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Lectin_C PF00059.16 EMC85565.1 - 4.4e-17 62.6 0.1 7.4e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.7 EMC85565.1 - 1.2e-05 24.1 0.1 1.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein adh_short PF00106.20 EMC85566.1 - 8.9e-21 74.5 0.2 1.2e-20 74.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC85566.1 - 3.2e-10 39.9 0.2 4.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMC85566.1 - 2.4e-08 34.0 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WW PF00397.21 EMC85566.1 - 4e-08 32.9 6.4 2.1e-07 30.6 0.3 2.5 2 0 0 2 2 2 1 WW domain NAD_binding_10 PF13460.1 EMC85566.1 - 0.00022 21.2 0.5 0.0011 19.0 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMC85566.1 - 0.001 18.5 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC85566.1 - 0.054 12.3 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain HAD PF12710.2 EMC85566.1 - 0.079 13.1 0.0 0.31 11.1 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase YjeF_N PF03853.10 EMC85566.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus PerB PF06590.6 EMC85566.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 PerB protein Exo_endo_phos PF03372.18 EMC85568.1 - 2.7e-08 34.0 0.0 4.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SCPU PF05229.10 EMC85568.1 - 0.017 15.1 0.5 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Spore Coat Protein U domain CBM_6 PF03422.10 EMC85568.1 - 0.035 14.2 0.1 0.092 12.9 0.1 1.7 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) LCAT PF02450.10 EMC85570.1 - 5.1e-82 275.9 0.1 6.3e-82 275.6 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EMC85570.1 - 3.2e-06 26.4 0.2 0.033 13.2 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 EMC85570.1 - 0.00025 21.0 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMC85570.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 EMC85570.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) 7tm_1 PF00001.16 EMC85571.1 - 8.1e-49 166.0 24.6 8.1e-49 166.0 17.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC85571.1 - 1.2e-07 31.2 27.3 1.4e-07 30.9 18.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC85571.1 - 7.8e-05 21.9 17.1 7.8e-05 21.9 11.9 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx His_kinase PF06580.8 EMC85571.1 - 0.05 13.5 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase DUF962 PF06127.6 EMC85571.1 - 2.3 8.1 5.2 39 4.2 3.6 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF962) RRM_6 PF14259.1 EMC85572.1 - 7.2e-50 166.8 0.0 7.3e-17 61.1 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC85572.1 - 1.1e-14 53.8 0.0 0.0026 17.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85572.1 - 0.00035 20.3 0.3 2.9 7.8 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EMC85572.1 - 0.022 15.0 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Exonuclease DUF4283 PF14111.1 EMC85572.1 - 0.027 13.5 0.1 24 3.9 0.0 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4283) DUF4049 PF13258.1 EMC85572.1 - 0.16 10.8 0.0 0.44 9.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RHD PF00554.17 EMC85573.1 - 4.6e-23 81.7 0.2 1.7e-22 79.9 0.1 1.9 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 EMC85573.1 - 2e-05 24.5 0.7 7.3e-05 22.6 0.1 2.4 2 1 0 2 2 2 1 IPT/TIG domain Helicase_C PF00271.26 EMC85574.1 - 3.4e-22 78.0 0.0 1.1e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain 7tm_1 PF00001.16 EMC85575.1 - 2e-60 204.1 16.0 2.3e-60 203.8 11.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC85575.1 - 6.1e-08 32.1 14.7 8e-08 31.7 10.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 EMC85575.1 - 2.2e-07 30.3 15.7 2e-06 27.1 10.9 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srd PF10317.4 EMC85575.1 - 0.0071 15.3 18.5 0.03 13.3 12.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srb PF02175.11 EMC85575.1 - 0.044 13.3 6.8 0.11 12.0 4.7 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb UPF0182 PF03699.8 EMC85575.1 - 5.9 4.6 10.0 1.3 6.8 0.5 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0182) Peptidase_M19 PF01244.16 EMC85576.1 - 1.4e-104 349.4 0.0 1.6e-104 349.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF3491 PF11996.3 EMC85576.1 - 0.1 10.1 0.0 0.14 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) SNF PF00209.13 EMC85577.1 - 1.3e-237 789.4 34.5 1.5e-237 789.2 23.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ResIII PF04851.10 EMC85578.1 - 0.0068 16.2 1.8 0.56 10.0 0.5 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Adeno_shaft PF00608.12 EMC85578.1 - 0.017 14.6 0.1 35 4.2 0.0 3.2 3 0 0 3 3 3 0 Adenoviral fibre protein (repeat/shaft region) Ig_2 PF13895.1 EMC85578.1 - 0.16 12.1 1.9 13 5.9 0.1 2.8 1 1 1 2 2 2 0 Immunoglobulin domain LCE PF14672.1 EMC85578.1 - 0.44 11.0 7.3 0.51 10.8 1.2 2.3 1 1 1 2 2 2 0 Late cornified envelope GSu_C4xC__C2xCH PF09698.5 EMC85578.1 - 4.3 7.5 15.9 1.1 9.4 0.6 4.0 4 0 0 4 4 4 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Cytochrome_C7 PF14522.1 EMC85578.1 - 4.6 6.9 6.7 18 5.0 1.0 2.7 3 1 0 3 3 3 0 Cytochrome c7 MSA_2 PF00985.12 EMC85578.1 - 5.1 7.1 9.3 3.4 7.7 0.7 2.5 1 1 2 3 3 3 0 Merozoite Surface Antigen 2 (MSA-2) family DUF3668 PF12416.3 EMC85579.1 - 3.2e-127 424.4 0.0 3.2e-127 424.4 0.0 2.5 2 1 0 2 2 2 1 Cep120 protein Pkinase PF00069.20 EMC85580.1 - 4.9e-28 97.9 0.0 5.3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85580.1 - 5.5e-11 42.0 0.0 6e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase GRAM PF02893.15 EMC85582.1 - 7.2e-14 51.0 0.2 1.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Aldedh PF00171.17 EMC85583.1 - 2.8e-129 431.4 0.0 3.3e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 EMC85583.1 - 0.066 12.8 0.2 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Pkinase PF00069.20 EMC85586.1 - 9e-65 218.3 0.0 1.3e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85586.1 - 7.1e-26 90.8 0.0 1.2e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC85586.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family HPIP PF15226.1 EMC85586.1 - 0.0093 16.0 0.1 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 HCF-1 beta-propeller-interacting protein family Kinase-like PF14531.1 EMC85586.1 - 0.053 12.4 0.0 0.25 10.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like PLDc_3 PF13918.1 EMC85587.1 - 1.5e-34 118.9 0.0 4.1e-34 117.5 0.0 1.7 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.1 EMC85587.1 - 2.8e-28 98.2 0.0 1.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC85587.1 - 4.5e-13 48.5 3.4 3.1e-09 36.3 0.4 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Pkinase PF00069.20 EMC85588.1 - 1.1e-26 93.6 0.0 1.1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85588.1 - 2.9e-10 39.6 0.0 3.1e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMC85588.1 - 0.0014 17.4 0.1 0.0016 17.2 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EMC85588.1 - 0.0016 18.1 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC85588.1 - 0.024 13.6 0.0 0.044 12.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 EMC85588.1 - 0.027 13.5 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC85588.1 - 0.094 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EMC85588.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1180 PF06679.7 EMC85589.1 - 1.8e-25 89.7 2.5 1.9e-25 89.6 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) MCM2_N PF12619.3 EMC85589.1 - 0.032 14.2 0.7 0.033 14.1 0.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Mpv17_PMP22 PF04117.7 EMC85591.1 - 1.1e-16 60.1 4.4 7.7e-16 57.4 3.1 2.1 1 1 0 1 1 1 1 Mpv17 / PMP22 family N_Asn_amidohyd PF14736.1 EMC85592.1 - 5.3e-123 409.2 0.0 6.1e-123 409.0 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase RRN3 PF05327.6 EMC85593.1 - 1.9e-163 544.6 1.6 2.1e-163 544.4 1.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 EF-hand_2 PF09068.6 EMC85593.1 - 0.049 13.7 0.0 0.13 12.2 0.0 1.9 1 1 0 1 1 1 0 EF hand Ribosomal_L1 PF00687.16 EMC85594.1 - 1.3e-48 165.2 1.3 1.3e-48 165.2 0.9 2.3 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family GTP_EFTU PF00009.22 EMC85595.1 - 7.3e-49 165.7 0.0 1.5e-48 164.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC85595.1 - 3.1e-22 78.5 0.2 3.1e-22 78.5 0.2 2.7 4 0 0 4 4 4 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC85595.1 - 7.2e-07 29.2 0.1 1.9e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC85595.1 - 6.8e-05 22.8 0.1 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EMC85595.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Arf PF00025.16 EMC85595.1 - 0.051 12.8 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 EMC85595.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EMC85595.1 - 0.15 11.6 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CDV3 PF15359.1 EMC85595.1 - 0.87 9.6 6.5 1.9 8.5 4.5 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 RUN PF02759.14 EMC85597.1 - 2.9e-23 82.0 0.1 5.6e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 RUN domain PX PF00787.19 EMC85598.1 - 1.5e-18 66.5 1.0 1.5e-18 66.5 0.7 2.3 3 0 0 3 3 3 1 PX domain Rootletin PF15035.1 EMC85598.1 - 0.0065 16.4 5.1 0.0065 16.4 3.5 2.6 3 1 0 3 3 3 1 Ciliary rootlet component, centrosome cohesion NYD-SP28_assoc PF14775.1 EMC85598.1 - 0.025 14.2 6.9 1.3 8.7 1.0 3.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain PXA PF02194.10 EMC85598.1 - 0.075 12.6 1.9 1 8.8 0.4 2.4 2 0 0 2 2 2 0 PXA domain TSC22 PF01166.13 EMC85598.1 - 0.35 10.8 9.6 0.48 10.4 2.0 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 EMC85598.1 - 4.7 6.7 9.7 0.65 9.5 0.9 2.7 3 0 0 3 3 3 0 IncA protein PhoU_div PF01865.11 EMC85598.1 - 8.4 5.5 9.2 1.6 7.8 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF47 Metallophos PF00149.23 EMC85599.1 - 3.9e-13 49.2 1.7 8.5e-13 48.1 1.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC85599.1 - 7.7e-11 42.0 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ERCC4 PF02732.10 EMC85600.1 - 6.6e-29 100.5 0.0 2e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 EMC85600.1 - 1.2e-05 25.3 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain RPEL PF02755.10 EMC85601.1 - 9.6e-24 82.0 14.9 4.3e-09 35.4 0.0 4.1 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.22 EMC85601.1 - 6.6e-12 44.6 0.4 6.6e-12 44.6 0.3 2.5 2 0 0 2 2 2 1 SAP domain CAF1 PF04857.15 EMC85602.1 - 1.5e-69 234.2 1.5 2.5e-69 233.5 1.1 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.6 EMC85602.1 - 2.6e-46 155.4 0.4 4.9e-46 154.6 0.3 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.17 EMC85602.1 - 2.9e-05 23.6 0.0 0.00013 21.6 0.0 2.2 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 EMC85602.1 - 0.028 14.0 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85602.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_1 PF00536.25 EMC85603.1 - 7.2e-11 42.1 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.1 EMC85603.1 - 6.2e-09 35.5 12.1 1.4e-08 34.4 8.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMC85603.1 - 2.3e-08 33.5 13.1 4.5e-08 32.6 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.12 EMC85603.1 - 5.7e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 EMC85603.1 - 4.1e-06 26.7 13.8 8.8e-06 25.6 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC85603.1 - 5.5e-06 26.1 14.1 1.5e-05 24.7 9.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC85603.1 - 2.7e-05 23.7 7.9 4.6e-05 23.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC85603.1 - 0.0036 16.9 11.5 0.0072 16.0 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC85603.1 - 0.011 15.4 6.7 0.03 14.0 4.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EMC85603.1 - 0.016 15.0 4.5 0.038 13.8 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAM_PNT PF02198.11 EMC85603.1 - 0.019 14.7 0.2 0.055 13.2 0.2 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-rbx1 PF12678.2 EMC85603.1 - 0.23 11.6 8.8 0.51 10.4 6.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Phospholip_A2_1 PF00068.14 EMC85604.1 - 1e-36 125.7 14.1 1.1e-36 125.5 9.8 1.1 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 EMC85604.1 - 0.074 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP1 TPR_11 PF13414.1 EMC85605.1 - 4.2e-10 39.1 5.3 9.4e-10 37.9 0.2 2.4 1 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMC85605.1 - 1.3e-05 24.5 4.4 0.0034 16.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.19 EMC85605.1 - 3.8e-05 23.2 1.8 3.8e-05 23.2 1.3 4.2 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.3 EMC85605.1 - 0.00053 20.0 5.3 0.00053 20.0 3.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding TPR_2 PF07719.12 EMC85605.1 - 0.015 15.1 2.4 0.47 10.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-met PF12874.2 EMC85605.1 - 0.016 15.4 5.8 0.064 13.4 4.0 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-CCCH_2 PF14608.1 EMC85605.1 - 0.061 13.3 0.4 0.061 13.3 0.3 4.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Thioredoxin PF00085.15 EMC85606.1 - 5.3e-23 80.6 0.0 2.2e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EMC85606.1 - 5.9e-07 29.6 0.6 0.018 15.2 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EMC85606.1 - 6.9e-07 29.2 0.0 0.041 13.6 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC85606.1 - 1e-05 25.5 0.5 0.0095 16.0 0.1 3.3 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EMC85606.1 - 0.00011 22.1 7.3 0.0088 16.0 0.0 2.9 3 0 0 3 3 2 2 Thioredoxin-like APG6 PF04111.7 EMC85606.1 - 0.0019 17.3 18.4 0.0034 16.4 12.7 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 ERM PF00769.14 EMC85606.1 - 0.024 14.2 25.9 0.036 13.5 18.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 EMC85606.1 - 0.038 11.8 10.0 0.055 11.3 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2992 PF11208.3 EMC85606.1 - 0.22 11.3 7.7 0.46 10.3 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) GAS PF13851.1 EMC85606.1 - 0.75 8.9 24.3 1.3 8.1 16.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding OmpH PF03938.9 EMC85606.1 - 1.2 9.0 20.5 2.6 7.9 14.2 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.7 EMC85606.1 - 2 6.7 10.0 3 6.1 6.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.3 EMC85606.1 - 3.1 6.9 19.1 5.5 6.1 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.6 EMC85606.1 - 5.4 6.7 19.6 0.41 10.3 3.1 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 rve PF00665.21 EMC85607.1 - 7.9e-05 22.7 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Zona_pellucida PF00100.18 EMC85608.1 - 1.1e-34 120.1 2.7 1.3e-34 119.8 1.8 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Neurexophilin PF06312.7 EMC85609.1 - 4.7e-50 169.8 0.0 7.6e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.14 EMC85609.1 - 2.2e-05 24.9 0.0 4.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat PC-Esterase PF13839.1 EMC85609.1 - 0.00018 21.3 0.0 0.00042 20.2 0.0 1.7 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p CD20 PF04103.10 EMC85609.1 - 0.13 12.2 0.1 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 CD20-like family LRR_4 PF12799.2 EMC85610.1 - 8.3e-30 101.8 18.1 1.4e-08 34.1 2.1 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EMC85610.1 - 1e-15 57.7 1.3 1e-12 47.9 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 EMC85610.1 - 6.8e-15 54.5 45.2 5.3e-08 32.4 4.7 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EMC85610.1 - 2.1e-05 23.9 16.7 0.071 13.1 0.2 7.1 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC85610.1 - 2.3e-05 23.8 16.6 6.5 7.4 0.1 8.1 8 0 0 8 8 8 1 Leucine rich repeat IQ PF00612.22 EMC85610.1 - 0.00013 21.2 0.1 0.00032 20.0 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_6 PF13516.1 EMC85610.1 - 0.11 12.5 27.6 0.34 11.1 0.6 7.4 7 1 1 8 8 8 0 Leucine Rich repeat Ribosomal_L24e PF01246.15 EMC85611.1 - 1.5e-18 66.3 1.4 1.5e-18 66.3 1.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e Red1 PF07964.6 EMC85611.1 - 0.48 8.5 7.7 0.56 8.2 5.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Band_3_cyto PF07565.8 EMC85611.1 - 0.54 9.7 4.4 0.63 9.5 3.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain WTX PF09422.5 EMC85611.1 - 1.7 7.5 7.9 2 7.2 5.5 1.0 1 0 0 1 1 1 0 WTX protein DUF4658 PF15555.1 EMC85611.1 - 5.5 6.8 8.5 1.1 9.0 3.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) PCNP PF15473.1 EMC85612.1 - 1.4e-71 239.6 12.9 1.6e-71 239.4 9.0 1.0 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family DUF4602 PF15375.1 EMC85612.1 - 0.034 14.2 5.6 0.069 13.2 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) MRI PF15325.1 EMC85612.1 - 4.4 8.3 12.7 0.94 10.4 0.5 2.2 1 1 0 2 2 2 0 Modulator of retrovirus infection tRNA_m1G_MT PF01746.16 EMC85613.1 - 5.8e-33 114.0 0.0 9.9e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase HIGH_NTase1 PF05636.6 EMC85613.1 - 0.021 13.9 0.4 0.031 13.3 0.3 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase DIM1 PF02966.11 EMC85614.1 - 5.6e-55 184.4 0.1 6.5e-55 184.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EMC85614.1 - 2e-05 24.1 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Arb2 PF09757.4 EMC85615.1 - 2.5e-19 69.3 0.1 7.5e-19 67.8 0.0 1.8 1 1 0 1 1 1 1 Arb2 domain DUF676 PF05057.9 EMC85615.1 - 0.0069 15.7 0.4 0.94 8.7 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMC85615.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_C48 PF02902.14 EMC85616.1 - 1.4e-34 119.6 1.0 3.8e-34 118.1 0.4 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SEA PF01390.15 EMC85617.1 - 1.3e-34 118.0 1.5 9.5e-20 70.2 0.2 2.8 2 0 0 2 2 2 2 SEA domain EGF PF00008.22 EMC85617.1 - 0.032 14.1 15.6 0.016 15.1 4.7 2.6 2 0 0 2 2 2 0 EGF-like domain fn3 PF00041.16 EMC85618.1 - 5.8e-12 45.5 1.6 1.4e-11 44.3 1.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF716 PF04819.7 EMC85619.1 - 1.4e-44 150.8 11.5 2.4e-44 150.1 8.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) TPR_11 PF13414.1 EMC85620.1 - 8.7e-52 172.6 28.6 6.3e-20 70.6 1.7 6.7 5 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EMC85620.1 - 7.2e-39 129.8 25.6 2.8e-09 36.1 0.6 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMC85620.1 - 5.9e-33 110.1 26.8 1.1e-06 28.0 0.2 10.7 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 EMC85620.1 - 6.2e-22 76.1 8.2 0.0011 19.3 0.0 8.4 5 2 4 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EMC85620.1 - 3.1e-20 70.3 19.5 0.0087 15.7 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMC85620.1 - 3.4e-19 68.5 20.5 4.3e-06 26.5 0.6 6.7 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMC85620.1 - 7.4e-18 63.2 15.0 0.007 16.4 0.0 9.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC85620.1 - 1.9e-16 60.2 9.2 0.0064 17.1 0.0 6.8 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC85620.1 - 5.8e-13 48.9 16.1 0.0029 17.9 0.0 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 EMC85620.1 - 1.8e-12 46.8 10.0 1.6 9.3 0.0 9.2 10 1 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMC85620.1 - 2.9e-12 46.2 4.0 0.0019 18.0 0.4 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC85620.1 - 1.5e-09 36.9 7.6 0.02 14.6 0.0 6.0 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC85620.1 - 8.8e-07 28.9 26.3 0.063 13.4 3.3 5.6 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EMC85620.1 - 2.2e-06 27.4 8.9 0.0049 16.7 0.8 4.2 3 2 0 3 3 2 2 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 EMC85620.1 - 2.5e-05 23.4 9.1 0.8 8.6 0.1 5.9 3 3 1 6 6 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EMC85620.1 - 0.011 15.5 5.0 0.61 9.8 0.0 4.4 5 0 0 5 5 4 0 Mad3/BUB1 homology region 1 PPR PF01535.15 EMC85620.1 - 0.019 14.9 0.3 6.4 6.9 0.0 3.7 3 0 0 3 3 2 0 PPR repeat RPN7 PF10602.4 EMC85620.1 - 0.032 13.6 0.4 0.032 13.6 0.3 3.5 4 1 0 4 4 4 0 26S proteasome subunit RPN7 MAS20 PF02064.10 EMC85620.1 - 0.038 13.9 0.3 8.7 6.2 0.0 3.4 3 0 0 3 3 3 0 MAS20 protein import receptor SHNi-TPR PF10516.4 EMC85620.1 - 4.3 6.6 8.1 8.3 5.7 0.0 4.0 5 0 0 5 5 5 0 SHNi-TPR CN_hydrolase PF00795.17 EMC85621.1 - 3.7e-35 120.9 0.0 5.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RabGAP-TBC PF00566.13 EMC85622.1 - 1.8e-22 79.8 1.5 3.1e-22 79.1 1.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 EMC85622.1 - 5.3e-08 33.1 0.0 3.8e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain CortBP2 PF09727.4 EMC85623.1 - 2.6e-79 265.2 26.2 2.6e-79 265.2 18.1 6.7 2 2 4 6 6 6 2 Cortactin-binding protein-2 CMS1 PF14617.1 EMC85624.1 - 7.6e-30 103.8 3.5 1.8e-29 102.5 2.5 1.5 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EMC85624.1 - 4.3e-05 23.0 0.0 6.3e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase efThoc1 PF11957.3 EMC85624.1 - 0.11 10.9 1.4 0.27 9.6 0.1 1.8 1 1 1 2 2 2 0 THO complex subunit 1 transcription elongation factor CDC50 PF03381.10 EMC85625.1 - 1e-86 290.5 3.7 1.4e-86 290.0 2.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family F5_F8_type_C PF00754.20 EMC85626.1 - 8.5e-28 96.7 0.4 1.4e-27 96.0 0.3 1.4 1 0 0 1 1 1 1 F5/8 type C domain CUB PF00431.15 EMC85626.1 - 6.8e-25 87.2 0.0 1.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain LCCL PF03815.14 EMC85626.1 - 8.3e-18 64.1 0.1 2.3e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 LCCL domain Syndecan PF01034.15 EMC85626.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Sex_peptide PF08138.6 EMC85626.1 - 0.05 13.4 0.2 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 Sex peptide (SP) family Laminin_G_2 PF02210.19 EMC85627.1 - 9.2e-110 361.9 6.8 5.7e-30 103.9 0.0 4.1 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.18 EMC85627.1 - 1.9e-77 257.5 2.7 5.2e-25 87.9 0.0 5.4 4 2 0 4 4 4 4 Laminin G domain Laminin_G_3 PF13385.1 EMC85627.1 - 1.1e-17 64.6 1.4 0.0004 20.6 0.0 4.3 4 0 0 4 4 4 4 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 EMC85627.1 - 1.8e-08 34.2 17.7 7.4e-05 22.6 4.8 2.7 2 0 0 2 2 2 2 EGF-like domain DUF1080 PF06439.6 EMC85627.1 - 0.0012 18.7 0.6 4.3 7.1 0.0 3.6 2 1 1 3 3 3 1 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 EMC85628.1 - 8.4e-23 80.8 0.1 1.3e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EMC85628.1 - 9.5e-11 41.8 0.2 3.6e-10 39.9 0.0 1.9 2 1 0 2 2 2 1 Laminin G domain 7tm_1 PF00001.16 EMC85629.1 - 2.8e-38 131.5 22.6 3.7e-38 131.1 15.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.1 EMC85629.1 - 6.2e-18 64.3 5.8 2.4e-05 23.9 1.5 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_5 PF13306.1 EMC85629.1 - 1.2e-10 41.2 0.2 8.7e-05 22.2 0.0 2.7 3 0 0 3 3 3 2 Leucine rich repeats (6 copies) GnHR_trans PF12369.3 EMC85629.1 - 0.00098 19.5 3.4 0.00098 19.5 2.4 2.0 2 1 0 2 2 2 1 Gonadotropin hormone receptor transmembrane region LRR_4 PF12799.2 EMC85629.1 - 0.15 11.7 10.6 3.7 7.2 0.2 4.1 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC85629.1 - 0.93 9.7 7.8 45 4.6 0.0 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat TFIIA PF03153.8 EMC85630.1 - 5.1e-88 296.5 18.5 1.9e-87 294.6 12.9 1.9 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.16 EMC85630.1 - 1.6e-57 194.5 1.0 2.6e-57 193.9 0.7 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Gasdermin PF04598.7 EMC85631.1 - 9.4e-30 103.7 0.1 1.1e-29 103.5 0.1 1.0 1 0 0 1 1 1 1 Gasdermin family MAP1B_neuraxin PF00414.12 EMC85632.1 - 4.5e-20 69.6 101.4 0.0035 16.5 0.9 14.6 13 0 0 13 13 13 13 Neuraxin and MAP1B repeat PGM_PMM_III PF02880.11 EMC85634.1 - 9.5e-28 96.5 0.0 1.7e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 EMC85634.1 - 1.6e-14 53.5 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMC85634.1 - 2.3e-13 50.3 0.0 5.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMC85634.1 - 0.0017 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain cobW PF02492.14 EMC85635.1 - 1.1e-46 158.5 0.1 1.5e-46 158.0 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EMC85635.1 - 3.1e-19 68.4 0.0 5.3e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 EMC85635.1 - 4.5e-06 26.2 0.8 0.0011 18.4 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EMC85635.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EMC85635.1 - 0.0068 16.1 0.3 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EMC85635.1 - 0.0069 16.2 0.1 0.08 12.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMC85635.1 - 0.013 15.4 0.7 0.068 13.1 0.4 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EMC85635.1 - 0.017 14.8 0.4 0.24 11.1 0.0 2.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EMC85635.1 - 0.02 15.0 0.2 0.062 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMC85635.1 - 0.027 13.6 0.1 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMC85635.1 - 0.03 14.6 0.4 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMC85635.1 - 0.032 14.5 0.2 0.063 13.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EMC85635.1 - 0.049 13.1 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NLE PF08154.7 EMC85635.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NLE (NUC135) domain QRPTase_C PF01729.14 EMC85635.1 - 0.055 12.9 0.5 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain AAA_19 PF13245.1 EMC85635.1 - 0.06 13.1 0.2 0.2 11.4 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 EMC85635.1 - 0.06 12.9 0.9 0.76 9.4 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EMC85635.1 - 0.071 13.4 0.8 0.071 13.4 0.5 2.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMC85635.1 - 0.072 12.1 0.1 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 EMC85635.1 - 0.082 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Ded_cyto PF06920.8 EMC85636.1 - 1.5e-72 242.5 1.8 3.8e-72 241.2 1.2 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EMC85636.1 - 7e-52 175.7 0.9 2.1e-51 174.1 0.1 2.3 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 EMC85636.1 - 8.3e-27 92.8 0.1 5.7e-25 87.0 0.1 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) Dmrt1 PF12374.3 EMC85637.1 - 3.8e-23 81.6 16.4 6.1e-23 80.9 4.0 3.0 3 0 0 3 3 3 2 Double-sex mab3 related transcription factor 1 Ustilago_mating PF05722.7 EMC85637.1 - 0.0063 15.8 0.9 0.0081 15.5 0.6 1.1 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Tol_Tol_Ttg2 PF05494.7 EMC85637.1 - 0.062 12.8 0.1 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 DMA PF03474.9 EMC85638.1 - 9.4e-20 70.1 0.0 1.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 DMRTA motif DM PF00751.13 EMC85639.1 - 1.6e-20 72.3 13.7 3.7e-20 71.1 9.5 1.7 1 0 0 1 1 1 1 DM DNA binding domain Ion_trans PF00520.26 EMC85640.1 - 1.5e-26 92.9 1.4 1.5e-26 92.9 1.0 1.6 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC85640.1 - 8.5e-22 77.1 0.0 2.4e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC85640.1 - 7.2e-13 48.0 3.8 7.2e-13 48.0 2.7 1.9 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC85640.1 - 4.2e-05 22.1 5.1 5.8e-05 21.6 3.0 1.7 1 1 0 1 1 1 1 Polycystin cation channel SHP PF03579.8 EMC85640.1 - 0.073 12.4 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Small hydrophobic protein Myb_CC_LHEQLE PF14379.1 EMC85640.1 - 0.42 10.2 5.6 0.83 9.2 3.9 1.4 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif CARM1 PF11531.3 EMC85642.1 - 4.9e-17 61.6 2.8 6.7e-17 61.2 1.2 1.7 2 0 0 2 2 2 1 Coactivator-associated arginine methyltransferase 1 N terminal PRMT5 PF05185.11 EMC85642.1 - 4.9e-15 55.3 0.2 6.4e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 EMC85642.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EMC85642.1 - 2.5e-09 37.6 0.0 7.7e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC85642.1 - 3.1e-09 36.8 0.0 4.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC85642.1 - 4.1e-08 32.9 0.0 9.7e-08 31.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC85642.1 - 3.2e-07 29.8 0.0 1.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EMC85642.1 - 2.8e-06 26.2 0.0 4.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 EMC85642.1 - 6.9e-06 26.4 0.0 1.7e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC85642.1 - 5.2e-05 23.0 0.0 0.00026 20.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC85642.1 - 0.00013 22.2 0.0 0.00044 20.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EMC85642.1 - 0.00026 20.6 0.1 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EMC85642.1 - 0.00049 19.5 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.15 EMC85642.1 - 0.00058 19.0 0.0 0.00086 18.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EMC85642.1 - 0.0012 19.2 0.0 0.0044 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 EMC85642.1 - 0.025 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EMC85642.1 - 0.054 13.1 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RFX_DNA_binding PF02257.10 EMC85643.1 - 3.1e-39 133.0 0.2 1.5e-38 130.8 0.0 2.3 3 0 0 3 3 3 1 RFX DNA-binding domain Pox_D5 PF03288.11 EMC85643.1 - 0.035 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like zf-C2H2 PF00096.21 EMC85644.1 - 5.5e-16 57.8 25.9 0.0017 18.5 0.7 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC85644.1 - 1.1e-13 50.7 22.5 6.2e-06 26.2 0.5 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC85644.1 - 4.2e-10 39.2 25.2 0.0069 16.6 0.1 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger EpoR_lig-bind PF09067.5 EMC85644.1 - 0.11 12.5 0.2 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding zf-met PF12874.2 EMC85644.1 - 2.7 8.3 6.0 5.6 7.3 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SDF PF00375.13 EMC85645.1 - 5.4e-133 443.5 26.2 6.1e-133 443.3 18.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family YbjQ_1 PF01906.12 EMC85646.1 - 6.7e-07 29.7 3.0 0.011 16.1 0.0 4.4 4 1 0 4 4 4 3 Putative heavy-metal-binding Glyco_transf_29 PF00777.13 EMC85647.1 - 1.1e-74 250.9 0.0 1.3e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Sulfotransfer_1 PF00685.22 EMC85648.1 - 1e-67 228.2 4.5 3e-65 220.1 3.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain CTP_transf_3 PF02348.14 EMC85649.1 - 1.7e-31 109.5 0.0 2.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Hydrolase_3 PF08282.7 EMC85649.1 - 3e-05 23.7 0.3 0.0014 18.2 0.0 2.9 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase ABC_membrane PF00664.18 EMC85650.1 - 4e-65 219.9 26.7 8.9e-35 120.4 2.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC85650.1 - 3.2e-52 176.4 0.2 1e-24 87.3 0.0 3.5 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 EMC85650.1 - 1.1e-08 35.4 0.9 0.018 14.9 0.1 4.4 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 EMC85650.1 - 4.9e-07 29.2 7.2 0.015 14.5 0.0 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EMC85650.1 - 1.4e-06 27.8 0.0 0.0051 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMC85650.1 - 2.9e-05 23.4 0.7 0.046 13.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMC85650.1 - 7.3e-05 22.0 0.2 0.029 13.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EMC85650.1 - 0.00019 21.8 0.0 0.7 10.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EMC85650.1 - 0.0016 18.4 0.0 1.1 9.1 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EMC85650.1 - 0.0036 16.4 0.1 0.33 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 EMC85650.1 - 0.0041 15.7 0.7 1.1 7.6 0.0 3.2 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 EMC85650.1 - 0.0049 16.3 0.5 1.2 8.5 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EMC85650.1 - 0.0072 16.4 0.1 5.5 7.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC85650.1 - 0.0089 16.0 0.3 0.23 11.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EMC85650.1 - 0.025 14.2 0.1 0.3 10.7 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase DUF815 PF05673.8 EMC85650.1 - 0.028 13.3 0.0 3.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SE PF00437.15 EMC85650.1 - 0.029 13.2 0.0 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EMC85650.1 - 0.031 13.7 0.5 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 EMC85650.1 - 0.078 12.4 0.1 2.3 7.6 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 EMC85650.1 - 0.24 12.2 1.1 7.7 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain FAM177 PF14774.1 EMC85650.1 - 0.47 10.3 4.7 2.1 8.3 3.3 2.1 1 0 0 1 1 1 0 FAM177 family AAA_23 PF13476.1 EMC85650.1 - 0.47 10.7 10.7 26 5.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMC85650.1 - 0.75 9.6 4.4 1.1 9.0 0.0 3.2 3 0 0 3 3 3 0 Dynamin family IRK PF01007.15 EMC85651.1 - 1e-160 534.1 2.7 1.3e-160 533.8 1.9 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ldh_1_N PF00056.18 EMC85652.1 - 2.2e-50 170.1 0.8 3.1e-50 169.6 0.6 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMC85652.1 - 2.4e-30 105.5 0.0 4.1e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EMC85652.1 - 0.00014 21.2 0.0 0.00035 19.9 0.0 1.7 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Ldh_1_N PF00056.18 EMC85653.1 - 3.5e-50 169.5 1.0 4.9e-50 169.0 0.7 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMC85653.1 - 9.2e-29 100.3 0.0 2.1e-28 99.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EMC85653.1 - 0.00024 20.4 0.2 0.00065 19.0 0.0 1.7 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase Glycogen_syn PF05693.8 EMC85654.1 - 0 1185.8 0.0 0 1185.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EMC85654.1 - 7.8e-07 28.6 0.0 4.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Spexin PF15171.1 EMC85655.1 - 3.2e-43 145.6 2.1 3.2e-43 145.6 1.5 1.5 2 0 0 2 2 2 1 Neuropeptide secretory protein family, NPQ, spexin MRVI1 PF05781.7 EMC85657.1 - 1.2e-145 486.0 5.9 1.4e-145 485.8 4.1 1.0 1 0 0 1 1 1 1 MRVI1 protein SSFA2_C PF14723.1 EMC85657.1 - 0.06 13.0 0.8 0.12 12.0 0.6 1.4 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus RasGAP_C PF03836.10 EMC85657.1 - 0.25 11.0 5.6 2.6 7.7 0.3 2.5 1 1 1 2 2 2 0 RasGAP C-terminus DUF919 PF06034.6 EMC85657.1 - 0.42 10.2 4.5 0.28 10.8 1.3 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Complex1_LYR PF05347.10 EMC85658.1 - 4e-15 55.3 0.2 7e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC85658.1 - 2.6e-13 49.9 0.2 4.3e-13 49.2 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMC85658.1 - 4.5e-07 30.3 1.1 4.9e-07 30.1 0.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Nbl1_Borealin_N PF10444.4 EMC85658.1 - 0.13 11.6 0.2 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal DUF2635 PF10948.3 EMC85658.1 - 0.13 11.5 0.0 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Ras PF00071.17 EMC85659.1 - 2.5e-58 196.0 0.0 3e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC85659.1 - 2.7e-20 73.0 0.0 4.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC85659.1 - 7.8e-10 38.2 0.0 9.8e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC85659.1 - 2e-08 33.8 0.2 1.5e-07 31.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC85659.1 - 9e-06 25.6 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EMC85659.1 - 0.00028 19.7 0.1 0.0053 15.5 0.0 2.1 2 0 0 2 2 2 1 ArgK protein Gtr1_RagA PF04670.7 EMC85659.1 - 0.0017 17.5 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EMC85659.1 - 0.002 17.4 0.0 0.017 14.4 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 EMC85659.1 - 0.011 14.7 0.1 1.4 7.7 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EMC85659.1 - 0.013 14.9 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EMC85659.1 - 0.016 14.7 0.4 0.46 9.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMC85659.1 - 0.026 14.6 0.1 0.73 9.9 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 EMC85659.1 - 0.026 13.9 0.0 0.075 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EMC85659.1 - 0.035 13.1 0.4 0.073 12.0 0.0 1.9 2 1 0 2 2 2 0 Septin DUF258 PF03193.11 EMC85659.1 - 0.052 12.7 0.7 0.11 11.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMC85659.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMC85659.1 - 0.1 12.5 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ThiF PF00899.16 EMC85659.1 - 0.16 11.7 0.5 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 ThiF family RA PF00788.18 EMC85660.1 - 1.1e-05 25.8 0.0 3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TBPIP PF07106.8 EMC85660.1 - 0.0045 16.5 16.2 0.0045 16.5 11.2 3.1 1 1 1 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 EMC85660.1 - 0.016 14.3 4.1 0.76 8.9 1.0 3.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Herpes_IE68 PF02479.11 EMC85660.1 - 0.039 13.1 4.9 0.22 10.7 0.6 2.5 2 0 0 2 2 2 0 Herpesvirus immediate early protein Tropomyosin PF00261.15 EMC85660.1 - 0.21 10.6 41.9 0.15 11.0 18.2 2.3 1 1 1 2 2 2 0 Tropomyosin DUF3584 PF12128.3 EMC85660.1 - 0.72 7.1 33.4 1.1 6.5 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.7 EMC85660.1 - 1.7 8.6 7.3 0.51 10.2 0.4 3.8 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Tropomyosin_1 PF12718.2 EMC85660.1 - 2.3 8.0 47.1 5 6.9 19.1 2.5 1 1 1 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 EMC85660.1 - 3.2 7.8 29.3 1.5 8.9 3.2 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HLH PF00010.21 EMC85661.1 - 1.2e-12 47.3 1.1 1.8e-12 46.7 0.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC85661.1 - 3.2e-11 42.7 0.3 8.3e-11 41.4 0.2 1.8 1 0 0 1 1 1 1 Hairy Orange Oscp1 PF10188.4 EMC85661.1 - 0.0079 16.0 0.2 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 HTH_Mga PF08280.6 EMC85661.1 - 0.21 11.3 2.6 3.1 7.6 0.0 2.6 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CD20 PF04103.10 EMC85662.1 - 3e-16 59.7 13.6 4.4e-16 59.1 9.5 1.2 1 0 0 1 1 1 1 CD20-like family DUF4064 PF13273.1 EMC85662.1 - 0.009 16.1 3.3 0.075 13.1 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF4064) DUF2371 PF10177.4 EMC85662.1 - 0.011 15.6 0.1 0.35 10.7 0.1 2.2 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF1686 PF07937.6 EMC85662.1 - 0.021 14.4 0.8 0.036 13.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) UPF0093 PF03653.8 EMC85662.1 - 0.28 11.1 3.4 2.2 8.2 0.6 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0093) DUF2207 PF09972.4 EMC85662.1 - 0.54 8.7 1.8 1.6 7.2 1.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Mito_morph_reg PF14972.1 EMC85662.1 - 1.1 8.6 5.9 0.21 10.9 1.7 1.6 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator PgaD PF13994.1 EMC85662.1 - 1.6 8.1 5.4 1.3 8.4 0.2 2.2 2 0 0 2 2 2 0 PgaD-like protein Ndc1_Nup PF09531.5 EMC85662.1 - 2.2 6.5 10.7 0.03 12.7 1.6 2.1 3 0 0 3 3 3 0 Nucleoporin protein Ndc1-Nup Otopetrin PF03189.8 EMC85662.1 - 3.9 6.3 8.9 11 4.8 2.3 2.4 3 0 0 3 3 3 0 Otopetrin TcpE PF12648.2 EMC85662.1 - 4.1 7.5 5.5 0.52 10.4 0.8 1.8 2 0 0 2 2 2 0 TcpE family NYAP_C PF15452.1 EMC85664.1 - 0.05 12.6 0.2 0.059 12.3 0.1 1.0 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Sec2p PF06428.6 EMC85665.1 - 0.0028 17.4 1.8 0.0032 17.2 1.2 1.1 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p T4SS PF07996.6 EMC85665.1 - 0.0093 15.8 0.2 0.011 15.6 0.2 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins Mating_N PF12731.2 EMC85665.1 - 0.0095 15.7 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Mating-type protein beta 1 IncA PF04156.9 EMC85665.1 - 0.011 15.3 1.7 0.012 15.2 1.1 1.0 1 0 0 1 1 1 0 IncA protein Glutaredoxin2_C PF04399.8 EMC85665.1 - 0.012 15.1 1.8 0.035 13.6 0.9 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Tropomyosin_1 PF12718.2 EMC85665.1 - 0.013 15.3 2.3 0.015 15.1 1.6 1.1 1 0 0 1 1 1 0 Tropomyosin like COG2 PF06148.6 EMC85665.1 - 0.016 15.0 2.1 0.02 14.7 1.4 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.8 EMC85665.1 - 0.023 15.4 0.8 0.028 15.1 0.6 1.1 1 0 0 1 1 1 0 Occludin homology domain AATF-Che1 PF13339.1 EMC85665.1 - 0.039 14.1 0.5 0.043 13.9 0.3 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Spc7 PF08317.6 EMC85665.1 - 0.045 12.4 4.3 0.053 12.1 3.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EMC85665.1 - 0.058 12.3 1.2 0.061 12.2 0.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Retrotrans_gag PF03732.12 EMC85665.1 - 0.069 13.2 0.7 0.086 12.9 0.5 1.1 1 0 0 1 1 1 0 Retrotransposon gag protein Spc24 PF08286.6 EMC85665.1 - 0.076 12.7 3.2 0.099 12.3 2.2 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF713 PF05218.9 EMC85665.1 - 0.082 12.6 0.6 0.088 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Ran-binding PF05508.6 EMC85665.1 - 0.095 11.5 0.3 0.095 11.5 0.2 1.2 1 0 0 1 1 1 0 RanGTP-binding protein EMP24_GP25L PF01105.19 EMC85665.1 - 0.097 12.3 0.7 0.11 12.2 0.5 1.0 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Prefoldin_2 PF01920.15 EMC85665.1 - 0.1 12.3 4.3 0.12 12.1 3.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit DUF4294 PF14127.1 EMC85665.1 - 0.1 12.2 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) FliD_N PF02465.13 EMC85665.1 - 0.1 12.9 0.7 0.12 12.7 0.5 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF812 PF05667.6 EMC85665.1 - 0.11 10.9 2.4 0.12 10.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4613 PF15390.1 EMC85665.1 - 0.12 10.4 0.5 0.13 10.3 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Sec8_exocyst PF04048.9 EMC85665.1 - 0.13 11.9 2.3 0.15 11.7 1.6 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Pox_A_type_inc PF04508.7 EMC85665.1 - 0.15 11.8 5.0 0.37 10.7 0.6 2.8 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat EzrA PF06160.7 EMC85665.1 - 0.17 10.0 3.4 0.21 9.7 2.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA EAP30 PF04157.11 EMC85665.1 - 0.21 10.7 3.0 0.24 10.5 2.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family PRCC PF10253.4 EMC85665.1 - 0.31 11.7 3.6 0.36 11.5 2.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4404 PF14357.1 EMC85665.1 - 0.34 11.3 4.3 0.44 10.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF883 PF05957.8 EMC85665.1 - 0.39 11.1 2.0 0.56 10.6 1.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SlyX PF04102.7 EMC85665.1 - 2.5 8.5 7.7 3.6 8.0 5.2 1.5 1 1 0 1 1 1 0 SlyX Kinetocho_Slk19 PF12709.2 EMC85665.1 - 3.6 7.7 6.6 8.3 6.5 4.1 1.8 1 1 1 2 2 2 0 Central kinetochore-associated Med9 PF07544.8 EMC85665.1 - 3.8 7.3 6.3 0.74 9.5 0.5 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RYDR_ITPR PF01365.16 EMC85666.1 - 3.6e-13 49.2 0.1 8.7e-13 47.9 0.0 1.7 2 0 0 2 2 2 1 RIH domain He_PIG PF05345.7 EMC85667.1 - 0.00038 20.3 0.1 0.011 15.7 0.0 3.2 2 0 0 2 2 2 1 Putative Ig domain DUF2151 PF10221.4 EMC85668.1 - 0 1033.0 3.2 0 1032.8 2.2 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF837 PF05769.6 EMC85669.1 - 2e-75 252.3 25.7 2.3e-75 252.0 17.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF837) Tho2 PF11262.3 EMC85669.1 - 0.0029 16.6 4.8 0.0029 16.6 3.3 2.0 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 ZYG-11_interact PF05884.7 EMC85669.1 - 0.24 10.4 2.0 0.37 9.8 1.4 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 CotJB PF12652.2 EMC85669.1 - 0.24 11.4 2.0 0.79 9.8 0.1 2.3 2 0 0 2 2 2 0 CotJB protein FUSC PF04632.7 EMC85669.1 - 0.29 9.4 5.6 0.34 9.2 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hemerythrin PF01814.18 EMC85669.1 - 0.31 11.2 12.3 0.18 11.9 2.7 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF3452 PF11934.3 EMC85669.1 - 1.4 8.2 4.5 3.7 6.8 2.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) bZIP_1 PF00170.16 EMC85669.1 - 3.1 7.8 21.6 2.1 8.3 0.4 4.5 3 2 1 4 4 4 0 bZIP transcription factor ArsA_ATPase PF02374.10 EMC85669.1 - 3.1 6.7 11.6 0.4 9.6 1.9 2.0 1 1 1 2 2 2 0 Anion-transporting ATPase Mto2_bdg PF12808.2 EMC85669.1 - 4.8 7.3 17.1 2.8 8.0 3.1 3.5 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Sec20 PF03908.8 EMC85669.1 - 6 6.6 13.9 7.1 6.3 0.2 3.4 1 1 2 3 3 3 0 Sec20 NYD-SP28_assoc PF14775.1 EMC85669.1 - 7.6 6.3 14.9 1.9 8.2 1.6 3.4 3 1 0 3 3 3 0 Sperm tail C-terminal domain DUF4203 PF13886.1 EMC85670.1 - 2.4e-52 177.4 31.0 3.2e-52 177.0 21.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Med21 PF11221.3 EMC85671.1 - 1.8e-25 89.5 0.6 2.5e-25 89.1 0.4 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.6 EMC85671.1 - 0.0011 17.7 0.3 0.0013 17.4 0.2 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) HARE-HTH PF05066.8 EMC85671.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Pkinase PF00069.20 EMC85672.1 - 1.1e-60 205.0 0.1 5.2e-60 202.7 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85672.1 - 1.3e-27 96.4 1.7 2.8e-19 69.1 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EMC85672.1 - 2.2e-05 24.8 0.9 4.4e-05 23.9 0.6 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC85672.1 - 0.001 18.0 3.2 0.0026 16.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EMC85672.1 - 0.0018 17.3 0.7 0.0032 16.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC85672.1 - 0.0073 16.0 0.2 0.16 11.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_11 PF14598.1 EMC85673.1 - 1e-28 99.5 0.2 1.3e-24 86.3 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EMC85673.1 - 4.4e-23 81.2 0.0 2.4e-10 40.1 0.0 2.7 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.6 EMC85673.1 - 1.4e-21 76.4 0.0 1.9e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 EMC85673.1 - 4.3e-15 55.1 3.3 7.8e-15 54.3 1.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EMC85673.1 - 1.7e-13 50.8 0.0 1e-06 29.0 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMC85673.1 - 5e-07 29.7 0.0 0.0024 17.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EMC85673.1 - 0.0004 20.1 0.0 0.076 12.9 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_2 PF08446.6 EMC85673.1 - 0.056 13.8 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold SAM_1 PF00536.25 EMC85674.1 - 1.3e-31 108.6 13.1 6.9e-16 58.1 0.3 4.3 4 1 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC85674.1 - 7.5e-29 99.3 9.5 1.9e-14 53.2 0.0 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Nexin_C PF08628.7 EMC85674.1 - 0.002 18.1 0.9 0.0084 16.1 0.1 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal Integrase_DNA PF02920.10 EMC85674.1 - 0.0046 16.3 5.1 0.014 14.7 3.6 1.9 1 0 0 1 1 1 1 DNA binding domain of tn916 integrase DUF4407 PF14362.1 EMC85674.1 - 0.0075 15.2 10.6 0.062 12.2 2.1 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4407) SAM_PNT PF02198.11 EMC85674.1 - 0.014 15.1 5.6 0.64 9.8 0.6 3.4 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain Bacillus_HBL PF05791.6 EMC85674.1 - 0.33 10.2 12.1 0.41 9.9 6.2 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 EMC85674.1 - 1 8.4 5.5 3 6.9 1.2 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EMC85674.1 - 7.3 6.7 17.2 3.8 7.6 5.4 3.3 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Rab15_effector PF15208.1 EMC85675.1 - 5.3e-71 238.8 0.1 5.9e-71 238.6 0.1 1.0 1 0 0 1 1 1 1 Rab15 effector NAD_binding_1 PF00175.16 EMC85676.1 - 2.4e-33 114.9 0.0 4.8e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMC85676.1 - 4e-33 113.4 0.0 6.3e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMC85676.1 - 7.9e-06 25.8 0.0 0.00019 21.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMC85676.1 - 0.043 13.7 0.0 0.19 11.7 0.0 2.1 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain Gb3_synth PF04572.7 EMC85677.1 - 2.6e-43 146.9 0.5 3.6e-43 146.5 0.3 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 EMC85677.1 - 3.7e-22 78.6 0.0 1.3e-21 76.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMC85677.1 - 0.082 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.7 EMC85678.1 - 3.3e-43 146.6 0.3 4.7e-43 146.1 0.2 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 EMC85678.1 - 6e-22 77.9 0.0 1.5e-21 76.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMC85678.1 - 0.0049 15.4 0.0 0.0079 14.7 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EMC85678.1 - 0.011 14.9 0.1 0.034 13.2 0.0 1.9 3 0 0 3 3 3 0 Capsular polysaccharide synthesis protein Gb3_synth PF04572.7 EMC85679.1 - 1.3e-43 147.8 0.6 1.8e-43 147.5 0.4 1.1 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 EMC85679.1 - 1.9e-15 57.0 0.1 7.2e-15 55.2 0.0 1.9 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMC85679.1 - 0.042 12.3 0.0 0.06 11.8 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF1244 PF06844.6 EMC85679.1 - 0.087 12.6 0.0 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) Gb3_synth PF04572.7 EMC85680.1 - 1.5e-46 157.4 1.5 1.8e-46 157.1 1.0 1.1 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 EMC85680.1 - 3.1e-07 30.7 0.4 4.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif APO_RNA-bind PF05634.6 EMC85682.1 - 0.023 13.8 0.0 0.026 13.7 0.0 1.0 1 0 0 1 1 1 0 APO RNA-binding Gb3_synth PF04572.7 EMC85683.1 - 3.4e-43 146.5 0.2 5e-43 146.0 0.1 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 EMC85683.1 - 5.1e-21 74.9 0.0 1.6e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMC85683.1 - 0.078 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.7 EMC85684.1 - 3.5e-46 156.2 1.4 5.1e-46 155.7 1.0 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 EMC85684.1 - 1.3e-24 86.5 0.0 7.9e-24 84.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMC85684.1 - 0.08 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain ArfGap PF01412.13 EMC85685.1 - 1.9e-29 101.8 7.3 3.9e-29 100.8 1.2 2.6 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf FCH PF00611.18 EMC85686.1 - 7.6e-21 74.1 0.1 7.6e-21 74.1 0.1 3.7 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMC85686.1 - 2.4e-16 59.0 1.5 3e-16 58.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC85686.1 - 2.2e-15 55.7 0.1 4.9e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC85686.1 - 2.8e-08 33.0 0.0 6.2e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Tweety PF04906.8 EMC85686.1 - 0.4 9.0 1.3 0.68 8.2 0.9 1.3 1 0 0 1 1 1 0 Tweety PTPlike_phytase PF14566.1 EMC85686.1 - 4.9 7.1 6.8 3.6 7.6 2.7 2.3 1 1 1 2 2 2 0 Inositol hexakisphosphate TTL PF03133.10 EMC85687.1 - 4.6e-101 337.6 0.6 6.2e-101 337.1 0.5 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMC85687.1 - 1.8e-05 23.7 0.3 0.0018 17.1 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp bcl-2I13 PF12201.3 EMC85688.1 - 0.0006 19.3 0.0 0.00078 18.9 0.0 1.2 1 0 0 1 1 1 1 Bcl2-interacting killer, BH3-domain containing Bclx_interact PF08945.5 EMC85688.1 - 0.076 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Acyl_transf_1 PF00698.16 EMC85689.1 - 3.2e-16 59.5 0.1 5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain TspO_MBR PF03073.10 EMC85690.1 - 4.8e-51 172.1 12.5 5.4e-51 171.9 8.6 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1358 PF07096.6 EMC85690.1 - 3.2 7.4 7.5 0.29 10.8 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1358) TTL PF03133.10 EMC85691.1 - 1.9e-70 237.0 0.1 2.7e-70 236.5 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FXa_inhibition PF14670.1 EMC85692.1 - 8.8e-66 217.7 176.7 7e-13 48.4 6.3 12.0 12 1 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC85692.1 - 1.4e-38 130.0 86.0 4.2e-09 35.8 0.6 12.0 11 0 0 11 11 11 7 Complement Clr-like EGF-like GCC2_GCC3 PF07699.8 EMC85692.1 - 2e-30 104.0 33.6 5.8e-14 51.3 6.3 6.9 6 1 1 7 7 7 3 GCC2 and GCC3 EGF_CA PF07645.10 EMC85692.1 - 7.5e-30 102.6 170.9 2.1e-09 37.1 5.9 11.9 12 0 0 12 12 12 7 Calcium-binding EGF domain EGF_3 PF12947.2 EMC85692.1 - 1.2e-21 76.3 142.3 2.6e-10 40.0 6.6 11.4 10 0 0 10 10 10 8 EGF domain EGF PF00008.22 EMC85692.1 - 5.3e-21 74.2 133.8 1.6e-06 27.9 3.9 11.7 11 1 0 11 11 11 9 EGF-like domain CUB PF00431.15 EMC85692.1 - 5.2e-17 61.8 0.0 5.2e-17 61.8 0.0 2.5 3 0 0 3 3 3 1 CUB domain Orbi_NS3 PF01616.11 EMC85692.1 - 0.12 11.3 0.2 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Orbivirus NS3 hEGF PF12661.2 EMC85692.1 - 5.1 7.3 52.7 0.11 12.6 0.3 10.4 9 0 0 9 9 9 0 Human growth factor-like EGF Metallophos PF00149.23 EMC85693.1 - 2.9e-12 46.4 1.5 5.1e-12 45.6 1.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC85693.1 - 1.9e-07 31.0 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfotransfer_1 PF00685.22 EMC85694.1 - 8.2e-50 169.5 0.2 1.2e-49 169.0 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain FdsD PF11390.3 EMC85694.1 - 0.072 13.1 2.0 0.75 9.9 1.2 2.2 1 1 1 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Patatin PF01734.17 EMC85695.1 - 2.9e-06 27.3 0.0 5.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase CDC37_C PF08564.5 EMC85695.1 - 0.0099 15.7 0.3 0.12 12.2 0.1 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain Ish1 PF10281.4 EMC85695.1 - 0.13 12.3 0.2 19 5.4 0.0 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF1669 PF07894.7 EMC85696.1 - 2.5e-104 348.4 0.0 9.9e-104 346.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 EMC85696.1 - 0.0043 16.7 0.1 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain zf-RAG1 PF10426.4 EMC85698.1 - 0.41 10.6 4.7 9.2 6.3 0.1 3.0 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain PRY PF13765.1 EMC85700.1 - 1.7e-11 43.4 0.5 4.3e-11 42.1 0.4 1.7 1 1 0 1 1 1 1 SPRY-associated domain Ephrin PF00812.12 EMC85703.1 - 1.6e-56 189.8 0.2 2.1e-55 186.2 0.0 2.0 2 0 0 2 2 2 1 Ephrin Shisa PF13908.1 EMC85703.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 EMC85703.1 - 0.0044 16.7 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Podoplanin PF05808.6 EMC85703.1 - 0.017 14.7 0.3 0.026 14.0 0.1 1.4 1 1 0 1 1 1 0 Podoplanin Profilin PF00235.14 EMC85703.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Profilin EphA2_TM PF14575.1 EMC85703.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0560 PF10577.4 EMC85703.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Herpes_UL45 PF05473.7 EMC85703.1 - 0.14 11.5 0.1 0.6 9.4 0.0 2.1 3 0 0 3 3 3 0 UL45 protein TMEM154 PF15102.1 EMC85703.1 - 0.18 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family ARGLU PF15346.1 EMC85704.1 - 3.7e-49 166.3 59.4 3.7e-49 166.3 41.2 2.0 2 0 0 2 2 2 2 Arginine and glutamate-rich 1 PLRV_ORF5 PF01690.12 EMC85704.1 - 2.8 7.0 18.6 3.4 6.7 12.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SEO_C PF14577.1 EMC85706.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Sieve element occlusion C-terminus DNA_ligase_A_M PF01068.16 EMC85707.1 - 4.9e-53 179.4 0.2 8.9e-53 178.6 0.2 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMC85707.1 - 3e-44 150.9 0.1 6.3e-44 149.8 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_IV PF11411.3 EMC85707.1 - 9.6e-21 73.2 2.1 2e-20 72.2 1.5 1.6 1 0 0 1 1 1 1 DNA ligase IV DNA_ligase_A_C PF04679.10 EMC85707.1 - 4.7e-15 55.7 0.0 1.6e-14 54.0 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EMC85707.1 - 1.7e-13 50.5 0.2 1.1e-09 38.2 0.0 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EMC85707.1 - 0.0016 18.1 1.1 0.013 15.1 0.8 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain C9orf72-like PF15019.1 EMC85707.1 - 0.0045 16.2 0.0 0.034 13.3 0.0 2.3 2 0 0 2 2 2 1 C9orf72-like protein family Tox-REase-9 PF15650.1 EMC85707.1 - 0.042 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 DUF1395 PF07160.7 EMC85707.1 - 0.081 12.4 2.3 0.12 11.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) Abhydrolase_5 PF12695.2 EMC85708.1 - 3.3e-23 82.0 0.0 4.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC85708.1 - 5.3e-15 55.9 0.0 3.9e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC85708.1 - 1.3e-11 44.5 0.0 1.2e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EMC85708.1 - 1.7e-08 33.3 0.0 0.0001 20.9 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EMC85708.1 - 1.3e-06 28.0 0.0 0.0016 17.9 0.0 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMC85708.1 - 0.00022 20.8 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC85708.1 - 0.00039 19.7 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EMC85708.1 - 0.00065 19.4 0.0 0.0055 16.4 0.0 2.2 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EMC85708.1 - 0.0015 18.0 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 EMC85708.1 - 0.0037 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF1057 PF06342.7 EMC85708.1 - 0.0052 15.6 0.1 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.3 EMC85708.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF818 PF05677.7 EMC85708.1 - 0.024 13.3 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Esterase PF00756.15 EMC85708.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EMC85708.1 - 0.053 13.0 0.3 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.20 EMC85708.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 EMC85708.1 - 0.092 12.0 0.0 0.6 9.3 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 EMC85708.1 - 0.15 10.2 0.0 0.36 9.0 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II TNF PF00229.13 EMC85709.1 - 3.3e-17 62.2 0.0 5.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family KRAP_IP3R_bind PF14722.1 EMC85711.1 - 9.1e-45 152.1 2.1 4.2e-44 149.9 0.1 2.4 2 0 0 2 2 2 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain SSFA2_C PF14723.1 EMC85711.1 - 6.7e-23 81.3 24.5 7.3e-22 77.9 14.1 3.0 2 1 0 2 2 2 1 Sperm-specific antigen 2 C-terminus Neuro_bHLH PF12533.3 EMC85712.1 - 1.2e-43 148.6 2.9 1.2e-43 148.6 2.0 2.2 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor HLH PF00010.21 EMC85712.1 - 2.5e-16 59.0 0.8 2.5e-16 59.0 0.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Integrin_alpha2 PF08441.7 EMC85713.1 - 2.9e-97 326.4 0.1 3.9e-97 325.9 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 EMC85713.1 - 2.6e-18 65.1 14.5 1.1e-06 28.1 0.0 4.3 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.1 EMC85713.1 - 4.2e-11 43.0 11.0 2.4e-09 37.4 1.4 2.9 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 EMC85713.1 - 0.0003 20.3 0.3 0.00097 18.7 0.2 2.0 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.1 EMC85713.1 - 0.034 14.1 14.9 0.051 13.5 0.6 4.7 5 0 0 5 5 5 0 FG-GAP repeat GRIP PF01465.15 EMC85714.1 - 9.3e-12 44.2 0.4 4.7e-11 42.0 0.1 2.5 2 0 0 2 2 2 1 GRIP domain OmpH PF03938.9 EMC85714.1 - 0.00099 19.0 11.4 0.00099 19.0 7.9 21.0 3 1 15 18 18 18 3 Outer membrane protein (OmpH-like) 7tm_4 PF13853.1 EMC85715.1 - 5.8e-31 107.2 4.7 6.7e-31 107.0 3.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC85715.1 - 0.0089 15.1 2.8 0.01 14.9 1.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_M28 PF04389.12 EMC85716.1 - 8.6e-06 25.6 0.0 4.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 EMC85716.1 - 0.012 15.2 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain PA PF02225.17 EMC85716.1 - 0.14 11.8 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 PA domain WD40 PF00400.27 EMC85717.1 - 5.6e-70 228.9 25.2 3.3e-13 48.9 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC85717.1 - 3.4e-12 46.4 0.7 0.00087 19.0 0.1 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EMC85717.1 - 2.7e-10 39.6 0.1 1.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 LisH Apc4_WD40 PF12894.2 EMC85717.1 - 3.7e-05 23.1 0.0 6.3 6.3 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EMC85717.1 - 0.00089 18.1 0.0 0.02 13.7 0.0 2.4 3 0 0 3 3 3 1 Coatomer WD associated region Nup160 PF11715.3 EMC85717.1 - 0.0048 15.1 4.5 0.29 9.2 0.1 3.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EMC85717.1 - 0.016 13.0 0.5 0.21 9.3 0.3 2.5 1 1 0 1 1 1 0 IKI3 family TSP9 PF11493.3 EMC85717.1 - 0.054 14.0 0.2 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 CaKB PF03185.10 EMC85718.1 - 2.3e-92 307.8 8.6 2.6e-92 307.7 6.0 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit tRNA-synt_1g PF09334.6 EMC85718.1 - 0.031 12.9 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Pox_A9 PF04835.7 EMC85718.1 - 1.3 9.0 5.0 1.1 9.1 1.7 2.1 2 0 0 2 2 2 0 A9 protein conserved region zf-met PF12874.2 EMC85719.1 - 2.1e-23 81.7 15.8 7.5e-09 35.4 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC85719.1 - 1.7e-19 69.4 17.1 5.8e-07 29.4 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC85719.1 - 3.6e-09 36.6 11.8 0.012 15.7 0.3 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EMC85719.1 - 0.00077 18.9 18.2 0.086 12.4 2.1 3.6 3 1 0 3 3 3 2 U1 zinc finger AKAP95 PF04988.7 EMC85719.1 - 0.0015 18.2 7.5 0.013 15.3 0.3 3.0 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 EMC85719.1 - 0.0069 16.6 10.6 1.2 9.6 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-DBF PF07535.7 EMC85719.1 - 2.1 8.0 7.7 2 8.1 0.3 2.9 3 0 0 3 3 3 0 DBF zinc finger PI3Ka PF00613.15 EMC85720.1 - 8.7e-73 243.4 2.0 8.7e-73 243.4 1.4 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EMC85720.1 - 1.4e-52 178.4 2.9 2.1e-52 177.9 1.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.13 EMC85720.1 - 2.9e-39 133.2 1.2 2.2e-37 127.2 0.4 2.9 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 EMC85720.1 - 1.7e-32 112.1 0.0 3.2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_p85B PF02192.11 EMC85720.1 - 1.3e-31 107.8 0.3 3.2e-31 106.5 0.2 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF3023 PF11224.3 EMC85720.1 - 0.036 13.7 0.9 7.2 6.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3023) zf-C2H2 PF00096.21 EMC85721.1 - 5e-16 58.0 60.2 0.0037 17.5 0.7 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC85721.1 - 3e-15 55.3 51.9 0.0068 16.6 0.4 9.6 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC85721.1 - 9.4e-13 47.7 53.1 5e-05 23.3 0.1 9.7 9 0 0 9 9 9 6 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMC85721.1 - 5e-09 35.8 56.2 0.022 14.9 1.6 8.9 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EMC85721.1 - 0.0006 19.6 4.3 0.012 15.5 0.2 6.7 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC85721.1 - 1.3 9.2 50.1 6.2 6.9 0.7 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) CarbpepA_inh PF02977.10 EMC85721.1 - 1.3 8.6 14.7 1.5 8.4 0.0 5.0 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor Fzo_mitofusin PF04799.8 EMC85722.1 - 9.1e-80 266.0 3.6 9.1e-80 266.0 2.5 2.7 2 1 1 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.18 EMC85722.1 - 1.2e-23 83.8 0.0 1.2e-23 83.8 0.0 3.8 4 1 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 EMC85722.1 - 5.5e-07 29.5 1.1 2.3e-06 27.5 0.0 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase Apolipoprotein PF01442.13 EMC85722.1 - 0.008 15.7 12.9 0.018 14.5 0.4 2.6 1 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain AAA_29 PF13555.1 EMC85722.1 - 0.074 12.5 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EMC85722.1 - 1.5 9.0 17.7 3.3 7.9 0.7 3.6 3 1 0 3 3 3 0 AAA domain DUF1664 PF07889.7 EMC85722.1 - 2.7 7.8 10.3 0.2 11.4 0.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EMC85723.1 - 6.6e-55 181.1 26.3 1.3e-09 37.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC85723.1 - 6.1e-05 22.8 0.0 0.27 10.9 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A UL11 PF11094.3 EMC85723.1 - 0.0068 16.2 1.0 0.02 14.7 0.2 2.1 2 0 0 2 2 2 1 Membrane-associated tegument protein Nucleoporin_N PF08801.6 EMC85723.1 - 0.025 13.3 1.0 1.7 7.2 0.1 3.1 3 1 0 3 3 3 0 Nup133 N terminal like Actin PF00022.14 EMC85724.1 - 6.7e-144 479.1 0.0 7.6e-144 478.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMC85724.1 - 0.0023 16.6 0.0 0.011 14.3 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein gag-asp_proteas PF13975.1 EMC85724.1 - 0.076 12.8 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MobA_MobL PF03389.10 EMC85724.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 MobA/MobL family MRP-L47 PF06984.8 EMC85725.1 - 5.5e-29 99.9 2.0 5.5e-29 99.9 1.4 1.6 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) L31 PF09784.4 EMC85725.1 - 0.28 11.2 8.1 0.18 11.8 1.7 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 UPF0240 PF06784.6 EMC85725.1 - 0.97 9.0 7.0 1.5 8.4 1.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) NDUF_B5 PF09781.4 EMC85726.1 - 1.9e-70 235.9 4.7 7.1e-61 204.7 1.0 2.0 1 1 1 2 2 2 2 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit UCH PF00443.24 EMC85727.1 - 9.8e-49 165.8 0.0 1.4e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EMC85727.1 - 1.4e-21 75.7 0.1 6.5e-11 41.7 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP PF02148.14 EMC85727.1 - 2.2e-17 62.8 1.6 6.4e-15 55.0 0.0 2.8 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC85727.1 - 9.4e-16 58.0 0.0 1.5e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EMC85727.1 - 0.016 14.7 0.1 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain UBA_3 PF09288.5 EMC85727.1 - 0.062 12.9 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3371 PF11851.3 EMC85727.1 - 0.071 13.7 0.2 1.4 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) TPR_1 PF00515.23 EMC85728.1 - 1.5e-26 90.8 1.0 1.7e-05 24.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMC85728.1 - 9.8e-25 85.9 5.9 3.3e-11 42.6 0.0 4.3 2 2 3 5 5 5 5 TPR repeat TPR_2 PF07719.12 EMC85728.1 - 1.7e-21 74.3 7.2 0.00018 21.1 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMC85728.1 - 8.1e-18 63.0 9.5 0.0008 19.4 0.3 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC85728.1 - 1.2e-15 57.6 5.0 0.00094 19.7 0.0 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC85728.1 - 1.8e-14 52.9 11.4 0.0011 19.4 0.7 6.5 3 2 4 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMC85728.1 - 5.4e-13 49.0 6.8 0.00044 20.5 1.8 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 EMC85728.1 - 7.5e-11 41.7 2.2 0.00043 20.0 0.3 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC85728.1 - 2.8e-10 39.2 0.8 0.34 10.7 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC85728.1 - 7.1e-10 38.6 0.9 1.1e-05 25.2 0.1 3.8 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 EMC85728.1 - 3.4e-09 36.7 4.2 0.00021 21.3 0.4 4.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC85728.1 - 4.8e-08 32.2 3.4 0.21 11.4 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC85728.1 - 9.8e-08 32.0 1.2 0.0056 16.7 1.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC85728.1 - 3.5e-07 30.2 3.7 4.1 8.0 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF4248 PF14053.1 EMC85728.1 - 0.00081 18.9 0.3 0.0022 17.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4248) TPR_10 PF13374.1 EMC85728.1 - 0.0029 17.5 7.8 2.1 8.3 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EMC85728.1 - 0.01 15.6 0.0 5 7.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMC85728.1 - 0.011 14.9 4.8 9.6 5.5 0.3 3.6 3 0 0 3 3 3 0 SHNi-TPR BTAD PF03704.12 EMC85728.1 - 0.54 10.5 6.4 3.9 7.7 0.1 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EMC85728.1 - 0.87 9.5 3.2 41 4.1 0.1 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 EMC85729.1 - 9.3e-17 60.4 4.4 1e-12 47.4 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EMC85729.1 - 2.6e-13 48.9 0.2 0.00059 19.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC85729.1 - 5.1e-12 44.7 4.7 0.00048 19.8 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC85729.1 - 1.1e-07 31.8 0.1 0.04 14.5 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC85729.1 - 2.1e-07 30.2 1.9 0.18 11.6 0.0 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC85729.1 - 2.5e-06 27.3 0.6 0.024 14.5 0.0 3.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC85729.1 - 9.3e-06 26.1 0.9 7.3e-05 23.3 0.0 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC85729.1 - 9.6e-06 25.3 0.0 5.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC85729.1 - 1.1e-05 25.2 0.7 0.00033 20.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC85729.1 - 0.00021 21.5 1.9 0.0085 16.4 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat S1 PF00575.18 EMC85729.1 - 0.007 16.4 0.0 0.14 12.2 0.0 2.5 1 1 0 1 1 1 1 S1 RNA binding domain TPR_7 PF13176.1 EMC85729.1 - 0.12 12.2 1.4 49 4.0 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Mem_trans PF03547.13 EMC85729.1 - 2.1 6.5 7.1 52 1.9 6.4 2.1 2 0 0 2 2 2 0 Membrane transport protein CENP-F_leu_zip PF10473.4 EMC85730.1 - 3.7e-06 26.8 20.0 3.7e-06 26.8 13.9 9.1 1 1 7 8 8 8 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EMC85730.1 - 0.0073 15.9 154.3 0.052 13.1 13.3 7.6 1 1 7 8 8 8 5 IncA protein Macro_2 PF14519.1 EMC85730.1 - 0.12 11.4 0.5 0.34 10.0 0.4 1.7 1 0 0 1 1 1 0 Macro-like domain FXR1P_C PF12235.3 EMC85731.1 - 6e-65 218.1 19.1 6e-65 218.1 13.2 2.3 2 0 0 2 2 2 1 Fragile X-related 1 protein C terminal KH_1 PF00013.24 EMC85731.1 - 7.4e-19 67.1 1.6 4.8e-09 35.7 0.7 2.9 2 0 0 2 2 2 2 KH domain Agenet PF05641.7 EMC85731.1 - 1.1e-10 41.4 2.3 1.3e-10 41.2 0.1 2.2 2 0 0 2 2 2 1 Agenet domain KH_3 PF13014.1 EMC85731.1 - 2.6e-06 26.9 4.9 5.9e-06 25.7 0.3 3.3 4 0 0 4 4 4 1 KH domain KH_2 PF07650.12 EMC85731.1 - 0.00024 20.5 0.8 0.096 12.2 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EMC85731.1 - 0.12 12.0 5.0 0.61 9.7 0.2 3.3 3 1 1 4 4 4 0 KH domain Tombus_movement PF05318.7 EMC85731.1 - 0.49 11.0 6.8 0.57 10.8 0.3 2.8 1 1 1 2 2 2 0 Tombusvirus movement protein SOXp PF12336.3 EMC85733.1 - 1.8e-29 102.1 4.3 1.8e-29 102.1 3.0 2.5 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.14 EMC85733.1 - 2.8e-27 94.7 3.2 4.7e-27 94.0 2.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC85733.1 - 9.6e-12 45.1 1.8 1.7e-11 44.2 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain Hydrolase PF00702.21 EMC85736.1 - 9.3e-17 62.1 0.0 1.8e-15 57.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC85736.1 - 1.1e-16 60.5 0.0 1.1e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EMC85736.1 - 3.2e-16 60.0 0.0 7.2e-16 58.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC85736.1 - 1.5e-11 44.0 0.0 5.3e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC85736.1 - 0.00028 20.5 0.0 0.0078 15.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FIST_C PF10442.4 EMC85736.1 - 0.12 12.3 0.1 3.5 7.5 0.0 3.0 3 0 0 3 3 3 0 FIST C domain ATP-synt_8 PF00895.15 EMC85736.1 - 1.4 9.1 0.0 1.4 9.1 0.0 4.4 4 1 1 5 5 5 0 ATP synthase protein 8 Cullin_binding PF03556.10 EMC85737.1 - 1.4e-40 138.0 4.7 2.4e-40 137.2 0.7 2.2 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 EMC85737.1 - 5.5e-10 38.6 1.9 1.5e-09 37.2 0.0 2.7 3 0 0 3 3 3 1 UBA-like domain CPSase_L_D2 PF02786.12 EMC85738.1 - 1.7e-77 259.4 0.1 3e-77 258.6 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMC85738.1 - 1.3e-45 154.0 1.0 6.9e-45 151.6 0.2 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMC85738.1 - 8.1e-36 122.2 0.0 5.9e-35 119.4 0.0 2.4 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EMC85738.1 - 1.5e-16 60.6 0.1 3.5e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EMC85738.1 - 2.3e-16 59.2 0.9 2.3e-16 59.2 0.6 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EMC85738.1 - 3.8e-16 58.7 0.1 8.7e-16 57.5 0.1 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMC85738.1 - 1.8e-13 50.3 0.0 5.7e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMC85738.1 - 1.2e-09 37.7 0.1 3e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMC85738.1 - 9e-08 31.8 0.0 2.5e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EMC85738.1 - 2.6e-06 26.9 3.8 0.0032 17.0 0.0 3.1 3 0 0 3 3 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EMC85738.1 - 3.8e-06 27.1 0.1 0.034 14.4 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EMC85738.1 - 9e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EMC85738.1 - 0.00063 19.1 0.1 0.056 12.7 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EMC85738.1 - 0.00089 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 EMC85738.1 - 0.025 13.6 0.1 0.095 11.7 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.1 EMC85738.1 - 0.032 13.9 0.9 0.087 12.5 0.2 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Toxin_59 PF15537.1 EMC85738.1 - 0.067 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative toxin 59 SOBP PF15279.1 EMC85740.1 - 3.6 7.8 7.2 4.1 7.6 5.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RhoGEF PF00621.15 EMC85741.1 - 1.1e-30 106.8 8.1 1.1e-30 106.8 5.6 3.5 3 1 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 EMC85741.1 - 5.7e-10 39.2 0.0 4.4e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Spectrin PF00435.16 EMC85741.1 - 0.00021 21.5 0.3 0.00021 21.5 0.2 4.4 3 1 2 5 5 5 2 Spectrin repeat PH_10 PF15411.1 EMC85741.1 - 0.019 15.1 0.2 0.019 15.1 0.2 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Galactosyl_T PF01762.16 EMC85742.1 - 1.7e-47 161.5 0.0 2.7e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC85742.1 - 0.00068 18.9 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Fringe-like AAA PF00004.24 EMC85743.1 - 2e-17 63.6 0.1 7.5e-17 61.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EMC85743.1 - 2.3e-17 62.7 0.1 4.9e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EMC85743.1 - 9.6e-13 48.1 0.0 3.7e-11 42.9 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EMC85743.1 - 4.1e-09 35.6 0.0 9e-05 21.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EMC85743.1 - 4.9e-06 26.1 0.0 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMC85743.1 - 1.9e-05 24.7 0.1 0.0016 18.4 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMC85743.1 - 2.7e-05 24.2 0.1 0.00052 20.1 0.0 2.7 2 2 1 3 3 2 1 AAA domain AAA_11 PF13086.1 EMC85743.1 - 4.4e-05 23.1 0.3 0.00014 21.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMC85743.1 - 9e-05 22.1 0.0 0.00052 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMC85743.1 - 0.00032 20.6 0.0 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EMC85743.1 - 0.00045 19.7 0.3 0.001 18.6 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_24 PF13479.1 EMC85743.1 - 0.00045 19.8 0.0 0.0015 18.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMC85743.1 - 0.00058 18.8 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EMC85743.1 - 0.00091 18.4 0.0 0.021 14.0 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMC85743.1 - 0.0024 16.9 0.0 0.0063 15.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMC85743.1 - 0.011 14.5 0.1 3.4 6.2 0.0 2.4 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 EMC85743.1 - 0.012 15.2 1.5 1.5 8.4 0.0 2.5 1 1 2 3 3 3 0 Archaeal ATPase AAA_5 PF07728.9 EMC85743.1 - 0.014 15.1 0.2 0.11 12.2 0.0 2.4 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EMC85743.1 - 0.014 14.3 0.0 0.036 13.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EMC85743.1 - 0.02 14.4 0.0 0.65 9.4 0.0 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EMC85743.1 - 0.035 13.6 0.0 1.5 8.2 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_3 PF07726.6 EMC85743.1 - 0.041 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMC85743.1 - 0.043 13.2 0.2 0.7 9.2 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EMC85743.1 - 0.05 13.0 0.1 0.75 9.1 0.0 2.7 1 1 0 1 1 1 0 AAA-like domain PhoH PF02562.11 EMC85743.1 - 0.061 12.5 0.0 6.2 5.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 EMC85743.1 - 0.081 12.7 0.0 0.24 11.2 0.0 1.9 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EMC85743.1 - 0.084 13.7 0.1 0.43 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF1048 PF06304.6 EMC85743.1 - 0.096 12.9 0.1 0.77 10.0 0.0 2.4 2 1 0 3 3 2 0 Protein of unknown function (DUF1048) AAA_28 PF13521.1 EMC85743.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMC85743.1 - 0.14 11.5 0.1 0.33 10.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EMC85744.1 - 4.5e-42 143.4 1.2 8.1e-42 142.5 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC85744.1 - 1.5e-27 95.2 0.8 4.1e-27 93.8 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EMC85744.1 - 0.00011 21.8 0.1 0.00025 20.7 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EMC85744.1 - 0.0003 20.6 0.1 0.00074 19.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMC85744.1 - 0.0032 17.0 0.1 0.0067 16.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.18 EMC85744.1 - 0.021 13.5 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EMC85744.1 - 0.029 14.4 0.3 0.3 11.2 0.2 2.5 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EMC85744.1 - 0.035 13.2 0.1 0.11 11.5 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 EMC85744.1 - 0.055 13.2 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EMC85744.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.16 EMC85744.1 - 0.11 11.7 0.2 0.19 11.0 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Cystatin PF00031.16 EMC85745.1 - 3.3e-43 145.7 2.4 3.3e-22 78.4 0.1 2.2 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.12 EMC85745.1 - 2.9e-11 43.3 0.5 9.5e-05 22.4 0.1 2.4 2 0 0 2 2 2 2 Cathelicidin Spp-24 PF07448.6 EMC85745.1 - 0.0012 18.7 1.4 0.0012 18.7 1.0 2.1 2 0 0 2 2 2 1 Secreted phosphoprotein 24 (Spp-24) Anticodon_1 PF08264.8 EMC85746.1 - 7 6.3 6.1 31 4.2 0.6 2.7 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Cystatin PF00031.16 EMC85748.1 - 2.5e-12 46.7 0.0 3e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Cystatin domain Peptidase_C48 PF02902.14 EMC85749.1 - 2.6e-43 148.1 2.3 4.7e-43 147.3 1.6 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEK_C PF08766.6 EMC85749.1 - 0.0025 17.5 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 DEK C terminal domain HrpB4 PF09502.5 EMC85750.1 - 0.01 15.0 0.1 0.014 14.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) Pkinase_Tyr PF07714.12 EMC85751.1 - 1.9e-92 309.0 0.0 3.1e-92 308.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC85751.1 - 1e-73 246.8 0.2 1.6e-73 246.2 0.2 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC85751.1 - 8.5e-45 152.9 0.0 1.2e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC85751.1 - 2.2e-33 114.2 4.6 7.6e-16 58.0 0.1 3.8 4 0 0 4 4 4 2 Fibronectin type III domain EphA2_TM PF14575.1 EMC85751.1 - 1.3e-26 92.7 0.3 2.8e-26 91.7 0.2 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 EMC85751.1 - 4.2e-24 84.5 0.0 8.8e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC85751.1 - 8.7e-22 76.7 0.0 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 EMC85751.1 - 3.5e-05 23.2 9.2 3.5e-05 23.2 6.4 2.5 3 1 0 3 3 3 1 GCC2 and GCC3 Interfer-bind PF09294.5 EMC85751.1 - 0.00024 21.1 0.0 0.028 14.4 0.0 3.1 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF2039 PF10217.4 EMC85751.1 - 0.55 10.2 4.5 0.24 11.4 0.7 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) cEGF PF12662.2 EMC85751.1 - 9.8 5.9 9.9 21 4.8 2.1 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like RNA_pol_Rpb8 PF03870.10 EMC85752.1 - 1.3e-55 187.3 0.1 1.5e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 EPO_TPO PF00758.13 EMC85753.1 - 3.7e-25 88.4 0.5 4.3e-25 88.2 0.3 1.1 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin CHRD PF07452.7 EMC85754.1 - 2.2e-60 202.4 0.0 1.6e-25 89.9 0.0 3.1 3 0 0 3 3 3 3 CHRD domain VWC PF00093.13 EMC85754.1 - 0.11 12.6 7.4 0.18 11.9 5.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain Amnionless PF14828.1 EMC85754.1 - 1.9 6.9 9.9 2.8 6.3 6.8 1.2 1 0 0 1 1 1 0 Amnionless CHRD PF07452.7 EMC85755.1 - 1.2e-08 35.6 0.0 1.3e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 CHRD domain Voltage_CLC PF00654.15 EMC85756.1 - 1.2e-86 290.9 25.6 1.2e-86 290.9 17.7 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EMC85756.1 - 0.00025 20.7 0.2 0.0053 16.5 0.0 2.4 2 0 0 2 2 2 1 CBS domain HSP20 PF00011.16 EMC85757.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family FAM131 PF15010.1 EMC85758.1 - 3.3e-105 352.0 0.6 4.3e-105 351.6 0.4 1.1 1 0 0 1 1 1 1 Putative cell signalling PT PF04886.7 EMC85758.1 - 8.4 5.8 9.4 0.26 10.6 2.1 1.7 2 0 0 2 2 2 0 PT repeat MIF4G PF02854.14 EMC85759.1 - 1.2e-67 227.4 9.2 1.2e-67 227.4 6.4 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EMC85759.1 - 4e-28 97.3 0.2 2e-27 95.1 0.1 2.3 2 1 0 2 2 2 1 MA3 domain PC_rep PF01851.17 EMC85760.1 - 3.8e-25 86.6 16.3 3.7e-06 26.8 0.0 9.0 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMC85760.1 - 0.00053 20.2 0.2 0.31 11.3 0.0 4.0 3 1 0 3 3 3 1 HEAT repeats HSA PF07529.8 EMC85760.1 - 0.14 11.9 2.5 0.17 11.6 0.5 2.0 2 0 0 2 2 2 0 HSA DUF2370 PF10176.4 EMC85760.1 - 0.23 10.7 0.9 0.9 8.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Peptidase_M13_N PF05649.8 EMC85761.1 - 1.3e-123 412.9 0.4 1.6e-123 412.5 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EMC85761.1 - 3.4e-66 222.3 0.0 8.5e-66 221.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.13 EMC85761.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M48 ALG3 PF05208.8 EMC85764.1 - 1.2e-136 455.7 15.0 1.4e-136 455.5 10.4 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 EMC85764.1 - 0.054 12.4 21.8 0.046 12.6 14.2 1.4 1 1 0 1 1 1 0 EpsG family YqaJ PF09588.5 EMC85765.1 - 3.4e-20 72.5 0.0 5.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain Herpes_alk_exo PF01771.12 EMC85765.1 - 6.5e-10 38.0 0.0 4.7e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Herpesvirus alkaline exonuclease ABC_tran PF00005.22 EMC85766.1 - 3e-40 137.6 0.4 1.1e-19 71.0 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EMC85766.1 - 2.2e-22 78.7 5.7 2.2e-22 78.7 4.0 2.8 3 1 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 EMC85766.1 - 2e-15 57.5 0.2 3.3e-07 30.5 0.0 4.2 3 2 1 4 4 3 2 AAA domain SMC_N PF02463.14 EMC85766.1 - 3e-10 39.7 1.4 4.2e-05 22.8 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EMC85766.1 - 7.6e-07 29.3 0.6 0.033 14.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain NACHT PF05729.7 EMC85766.1 - 1.6e-06 27.8 0.1 0.058 13.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EMC85766.1 - 1.7e-06 27.4 0.2 0.15 11.0 0.1 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EMC85766.1 - 4.1e-06 27.6 0.4 0.084 13.6 0.0 3.4 4 0 0 4 4 2 2 AAA domain Miro PF08477.8 EMC85766.1 - 9.1e-06 26.1 0.0 0.079 13.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EMC85766.1 - 1.2e-05 25.3 3.9 0.059 13.3 0.0 3.1 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.24 EMC85766.1 - 1.6e-05 25.1 0.3 0.22 11.6 0.0 3.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMC85766.1 - 3.3e-05 23.3 0.1 0.032 13.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EMC85766.1 - 4.1e-05 22.8 0.0 0.081 12.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EMC85766.1 - 0.00013 21.6 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EMC85766.1 - 0.00033 20.2 0.1 1.8 7.9 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 EMC85766.1 - 0.0009 19.5 0.4 0.35 11.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EMC85766.1 - 0.001 18.9 1.3 0.028 14.2 0.0 3.3 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EMC85766.1 - 0.0011 18.8 0.0 0.49 10.3 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EMC85766.1 - 0.0017 17.7 0.0 0.4 10.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMC85766.1 - 0.002 18.2 0.0 0.48 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EMC85766.1 - 0.0021 18.0 1.2 13 5.6 0.0 4.1 3 1 1 4 4 4 0 AAA domain SbcCD_C PF13558.1 EMC85766.1 - 0.0034 17.2 0.1 0.04 13.8 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EMC85766.1 - 0.0045 16.8 0.1 4.9 7.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EMC85766.1 - 0.01 15.7 0.7 3.2 7.6 0.0 3.6 3 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EMC85766.1 - 0.011 15.2 0.1 3 7.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EMC85766.1 - 0.013 15.8 16.9 0.19 12.0 0.0 3.8 3 2 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EMC85766.1 - 0.021 13.6 0.0 0.41 9.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 EMC85766.1 - 0.024 13.6 0.0 5.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 EMC85766.1 - 0.026 14.1 0.0 8.9 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EMC85766.1 - 0.027 14.1 0.1 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 EMC85766.1 - 0.032 13.8 0.1 3.3 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Arf PF00025.16 EMC85766.1 - 0.038 13.2 0.2 1.4 8.1 0.0 2.9 3 0 0 3 3 2 0 ADP-ribosylation factor family DUF87 PF01935.12 EMC85766.1 - 0.049 13.4 9.6 0.28 10.9 0.0 3.8 5 0 0 5 5 3 0 Domain of unknown function DUF87 ArgK PF03308.11 EMC85766.1 - 0.05 12.3 0.0 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 EMC85766.1 - 0.061 12.7 0.1 4.5 6.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EMC85766.1 - 0.11 11.8 0.0 6.8 6.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 EMC85766.1 - 0.15 11.5 0.1 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Adap_comp_sub PF00928.16 EMC85767.1 - 1.5e-84 283.2 0.1 1.9e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMC85767.1 - 0.00016 21.4 0.1 0.00057 19.6 0.1 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain muHD PF10291.4 EMC85767.1 - 0.048 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Hexapep PF00132.19 EMC85768.1 - 8e-12 44.1 7.8 0.00075 18.8 0.7 4.4 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 EMC85768.1 - 3.2e-10 39.8 0.1 3.2e-10 39.8 0.1 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.1 EMC85768.1 - 0.6 9.7 9.9 5 6.7 1.7 3.5 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.22 EMC85769.1 - 5.7e-54 182.1 0.2 1.9e-31 109.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EMC85769.1 - 3.6e-44 151.2 32.6 5e-27 94.9 6.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMC85769.1 - 1.1e-11 44.4 6.2 0.0076 15.5 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC85769.1 - 1.3e-10 41.7 5.6 0.036 14.0 0.0 4.5 2 2 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EMC85769.1 - 0.00011 21.6 1.7 0.3 10.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EMC85769.1 - 0.00038 19.6 1.1 0.11 11.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 EMC85769.1 - 0.00092 19.1 1.1 1.1 9.2 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC85769.1 - 0.00093 19.0 0.5 0.034 13.9 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 EMC85769.1 - 0.0015 18.8 6.8 0.062 13.6 0.1 3.4 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EMC85769.1 - 0.0053 17.2 6.8 0.19 12.2 0.2 3.3 3 0 0 3 3 3 1 Miro-like protein AAA_17 PF13207.1 EMC85769.1 - 0.0089 16.8 2.2 1.7 9.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC85769.1 - 0.0092 16.2 0.1 1.7 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMC85769.1 - 0.0095 15.1 1.4 0.45 9.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 EMC85769.1 - 0.026 14.3 1.1 1.7 8.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_16 PF13191.1 EMC85769.1 - 0.038 13.9 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EMC85769.1 - 0.045 12.6 0.0 10 4.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 EMC85769.1 - 0.047 13.3 2.4 1.8 8.2 0.2 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EMC85769.1 - 0.051 12.9 0.1 6.6 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain LVIVD PF08309.6 EMC85769.1 - 0.096 11.6 0.1 0.23 10.4 0.1 1.6 1 0 0 1 1 1 0 LVIVD repeat FtsK_SpoIIIE PF01580.13 EMC85769.1 - 0.097 12.1 0.9 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EMC85769.1 - 0.11 11.9 2.6 0.13 11.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M1 PF01433.15 EMC85770.1 - 1.7e-51 175.5 0.0 2.1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EMC85770.1 - 4.5e-37 126.8 0.0 1.1e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EMC85770.1 - 8.2e-16 58.2 0.0 2.1e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2268 PF10026.4 EMC85770.1 - 0.0058 16.0 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) DUF1570 PF07607.6 EMC85770.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) Peptidase_C2 PF00648.16 EMC85771.1 - 2.8e-75 253.1 0.1 4e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMC85771.1 - 3.2e-60 202.0 0.0 2.8e-31 108.1 0.0 2.3 2 0 0 2 2 2 2 Calpain large subunit, domain III p450 PF00067.17 EMC85772.1 - 3.5e-121 404.9 0.0 4e-121 404.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_8 PF13855.1 EMC85773.1 - 3.6e-77 254.0 45.3 1.7e-15 56.4 1.3 6.1 1 1 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 EMC85773.1 - 3.2e-32 109.5 35.1 1.7e-09 37.1 0.1 7.5 3 3 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC85773.1 - 3.7e-23 81.6 0.0 6e-10 38.9 0.0 3.0 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC85773.1 - 2.9e-21 72.2 34.0 0.0028 17.4 0.0 11.3 12 0 0 12 12 12 8 Leucine Rich Repeat LRR_7 PF13504.1 EMC85773.1 - 2.9e-15 53.7 41.7 0.0063 16.5 0.1 10.9 11 0 0 11 11 11 5 Leucine rich repeat LRR_9 PF14580.1 EMC85773.1 - 8.6e-08 31.9 7.5 0.0011 18.6 0.2 4.0 1 1 3 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.1 EMC85773.1 - 3.1e-05 23.6 27.3 0.35 11.0 0.0 8.6 9 2 2 11 11 11 4 Leucine Rich repeat Hairy_orange PF07527.8 EMC85774.1 - 1e-20 73.1 0.2 1.8e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.21 EMC85774.1 - 0.00011 21.7 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_fiss_reg PF05308.6 EMC85774.1 - 1.2 8.4 3.8 0.66 9.3 0.3 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Dynamin_N PF00350.18 EMC85775.1 - 1.2e-36 126.0 0.2 1.2e-36 126.0 0.1 3.1 5 1 0 5 5 5 1 Dynamin family MMR_HSR1 PF01926.18 EMC85775.1 - 2.4e-05 24.2 0.0 0.00015 21.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC85775.1 - 0.00012 21.3 0.0 0.0065 15.7 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EMC85775.1 - 0.0017 18.8 0.0 0.028 14.8 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein DUF1593 PF07632.6 EMC85775.1 - 0.0049 16.2 0.0 0.016 14.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Ras PF00071.17 EMC85775.1 - 0.037 13.4 0.9 7.2 5.9 0.0 2.8 3 0 0 3 3 3 0 Ras family GCC2_GCC3 PF07699.8 EMC85775.1 - 0.43 10.1 1.5 0.65 9.6 0.3 1.8 2 0 0 2 2 2 0 GCC2 and GCC3 NPV_P10 PF05531.7 EMC85775.1 - 0.55 10.5 7.1 0.25 11.6 0.5 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_28 PF13521.1 EMC85775.1 - 3.4 7.5 7.4 3.5 7.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain E1-E2_ATPase PF00122.15 EMC85776.1 - 1.5e-37 128.8 0.0 3.3e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 EMC85776.1 - 6.5e-23 80.8 1.0 1.5e-22 79.7 0.7 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EMC85776.1 - 6.5e-21 75.3 0.0 1.6e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC85776.1 - 2.8e-14 54.0 0.0 3.6e-13 50.4 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMC85776.1 - 4.1e-07 29.3 0.0 1.1e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EMC85776.1 - 9.3e-06 25.5 0.0 2.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2620 PF10941.3 EMC85776.1 - 0.011 15.7 0.1 0.045 13.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF2620 LRAT PF04970.8 EMC85777.1 - 2.4e-38 130.9 0.0 2.9e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Calici_PP_N PF08405.6 EMC85777.1 - 0.042 12.6 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal NLPC_P60 PF00877.14 EMC85777.1 - 0.044 13.5 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family Peptidase_C97 PF05903.9 EMC85777.1 - 0.047 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-CCCH PF00642.19 EMC85778.1 - 2e-10 40.1 7.4 2.2e-05 24.0 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2217 PF10265.4 EMC85778.1 - 1.8 7.2 8.0 2.8 6.6 5.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) zf-CCCH_2 PF14608.1 EMC85778.1 - 7.6 6.7 10.6 8.2 6.5 1.6 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Glyco_tranf_2_4 PF13704.1 EMC85780.1 - 8.5e-10 38.8 0.1 1.3e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Aminotran_4 PF01063.14 EMC85780.1 - 0.0085 15.5 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Sen15 PF09631.5 EMC85781.1 - 1.4e-24 86.2 0.0 2.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein RNA_pol_Rpb5_C PF01191.14 EMC85781.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DUF4612 PF15389.1 EMC85782.1 - 6e-43 146.1 7.4 7e-43 145.8 5.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) tRNA-synt_1e PF01406.14 EMC85782.1 - 0.0023 17.0 0.1 0.0026 16.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Phasin PF05597.6 EMC85784.1 - 0.1 12.3 0.9 0.67 9.7 0.1 2.6 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) zf-C3HC4 PF00097.20 EMC85785.1 - 4.7e-10 38.9 10.4 8.4e-10 38.1 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC85785.1 - 3.9e-09 36.1 8.2 6.5e-09 35.4 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC85785.1 - 7.4e-08 32.2 9.3 1.2e-07 31.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC85785.1 - 1.1e-06 28.2 8.3 1.6e-06 27.6 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC85785.1 - 6.9e-06 25.6 8.7 1.2e-05 24.9 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC85785.1 - 3e-05 23.7 8.3 6e-05 22.8 5.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EMC85785.1 - 0.00012 21.5 5.9 0.0002 20.7 4.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EMC85785.1 - 0.00032 20.2 7.3 0.00064 19.2 5.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EMC85785.1 - 0.006 16.3 4.1 0.011 15.5 2.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EMC85785.1 - 0.018 14.5 7.3 0.031 13.7 5.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-UDP PF14569.1 EMC85785.1 - 0.029 14.0 0.9 0.092 12.5 0.6 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.1 EMC85785.1 - 0.056 13.1 7.1 0.15 11.7 4.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EMC85785.1 - 0.1 12.7 5.7 0.29 11.2 3.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC85785.1 - 0.18 11.6 2.5 0.35 10.7 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDC73 PF05179.9 EMC85785.1 - 0.31 10.3 1.9 0.49 9.7 1.3 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family zf-C4_Topoisom PF01396.14 EMC85785.1 - 0.73 9.3 3.8 0.21 11.0 0.5 1.7 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger TRM PF02005.11 EMC85786.1 - 2.8e-70 237.1 5.8 1.9e-59 201.4 0.7 3.4 2 1 1 3 3 3 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EMC85786.1 - 6.7e-06 25.8 0.1 1.4e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EMC85786.1 - 0.00018 21.1 0.0 0.00084 18.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMC85786.1 - 0.0017 17.7 0.1 0.0058 16.0 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.9 EMC85786.1 - 0.023 14.0 0.1 0.046 13.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC85786.1 - 0.025 15.1 0.0 0.087 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain zf-C2H2_4 PF13894.1 EMC85786.1 - 0.076 13.3 7.3 0.11 12.8 0.2 3.7 2 0 0 2 2 2 0 C2H2-type zinc finger Kelch_1 PF01344.20 EMC85787.1 - 9.1e-85 278.0 8.3 5.3e-15 54.6 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC85787.1 - 2.8e-54 179.1 4.3 2.2e-11 43.4 0.0 6.5 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EMC85787.1 - 1.4e-41 139.7 11.9 1.8e-08 34.2 0.1 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC85787.1 - 2.2e-38 129.7 4.4 4.3e-07 29.5 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC85787.1 - 2.3e-37 125.3 1.3 5.8e-05 22.6 0.0 6.8 6 0 0 6 6 6 6 Kelch motif BTB PF00651.26 EMC85787.1 - 1.3e-26 92.7 0.5 2e-26 92.1 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 EMC85787.1 - 3.1e-15 55.7 6.9 0.00051 19.9 0.0 6.2 6 0 0 6 6 6 3 Kelch motif BACK PF07707.10 EMC85787.1 - 1.8e-11 43.7 0.1 8.2e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch VLPT PF07122.6 EMC85787.1 - 0.0013 18.3 0.5 0.17 11.6 0.9 2.7 2 0 0 2 2 2 1 Variable length PCR target protein (VLPT) Rax2 PF12768.2 EMC85787.1 - 0.06 12.5 0.4 0.64 9.1 0.0 2.4 2 0 0 2 2 2 0 Cortical protein marker for cell polarity PQQ_3 PF13570.1 EMC85787.1 - 1.7 9.0 10.6 0.41 11.0 0.1 4.4 6 0 0 6 6 4 0 PQQ-like domain VWA_2 PF13519.1 EMC85790.1 - 0.029 14.4 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain RRM_6 PF14259.1 EMC85790.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ODR4-like PF14778.1 EMC85791.1 - 3.3e-112 374.7 1.6 4.2e-112 374.4 1.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like Phosducin PF02114.11 EMC85792.1 - 6.1e-20 71.0 3.1 6.7e-20 70.9 2.2 1.0 1 0 0 1 1 1 1 Phosducin tRNA_int_end_N2 PF12928.2 EMC85793.1 - 1.1e-05 24.7 21.9 12 5.4 0.3 8.9 1 1 9 11 11 11 11 tRNA-splicing endonuclease subunit sen54 N-term DUF1513 PF07433.6 EMC85793.1 - 0.59 8.9 13.1 11 4.7 2.2 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) MIT PF04212.13 EMC85794.1 - 3.8e-07 29.8 0.0 4.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Dpy-30 PF05186.8 EMC85795.1 - 3e-21 74.6 0.4 3e-21 74.6 0.3 1.5 2 0 0 2 2 2 1 Dpy-30 motif RIIa PF02197.12 EMC85795.1 - 0.0025 17.1 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Memo PF01875.12 EMC85796.1 - 2.8e-76 256.0 0.0 3.3e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Steroid_dh PF02544.11 EMC85797.1 - 9.3e-60 200.7 4.1 1.1e-59 200.5 2.8 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EMC85797.1 - 2.7e-06 26.8 0.1 3.4e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EMC85797.1 - 4.8e-05 23.4 0.7 9.9e-05 22.4 0.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase zf-DHHC PF01529.15 EMC85797.1 - 0.074 12.4 0.1 0.12 11.7 0.1 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase ELYS PF13934.1 EMC85798.1 - 9.8e-55 185.7 0.7 1.7e-54 184.9 0.5 1.4 1 0 0 1 1 1 1 Nuclear pore complex assembly PapD_N PF00345.15 EMC85799.1 - 0.0095 15.7 1.9 0.85 9.4 0.3 2.3 1 1 1 2 2 2 2 Pili and flagellar-assembly chaperone, PapD N-terminal domain V-set PF07686.12 EMC85800.1 - 4.1e-07 29.8 0.0 6e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ras PF00071.17 EMC85801.1 - 1.6e-13 50.3 0.0 1.8e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC85801.1 - 4.6e-06 27.1 0.0 5.1e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein PTPlike_phytase PF14566.1 EMC85802.1 - 2.1e-44 151.1 0.2 1.8e-36 125.4 0.0 2.9 3 0 0 3 3 3 2 Inositol hexakisphosphate Y_phosphatase PF00102.22 EMC85802.1 - 0.0027 17.0 0.0 0.044 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC85802.1 - 0.0063 16.7 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 Tyrosine phosphatase family START PF01852.14 EMC85803.1 - 1.1e-22 80.4 0.2 1.4e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.15 EMC85803.1 - 6.6e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Vitellogenin_N PF01347.17 EMC85804.1 - 3.6e-14 51.9 0.1 4.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.6 EMC85804.1 - 0.00087 18.2 0.1 0.0023 16.8 0.0 1.6 1 1 0 2 2 2 1 Domain of unknown function (DUF1943) HEAT_2 PF13646.1 EMC85804.1 - 0.037 14.3 1.4 0.082 13.1 0.1 2.3 2 1 0 2 2 2 0 HEAT repeats Pyridoxal_deC PF00282.14 EMC85805.1 - 8.1e-20 70.5 0.0 1.2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMC85805.1 - 1.1e-13 50.7 0.0 7.9e-13 47.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMC85805.1 - 0.012 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pterin_4a PF01329.14 EMC85806.1 - 4.4e-32 109.7 0.1 4.9e-32 109.5 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ZU5 PF00791.15 EMC85808.1 - 6.2e-36 122.1 0.0 1.2e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.17 EMC85808.1 - 7.2e-15 54.5 0.1 1.4e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.11 EMC85808.1 - 2.6e-11 43.2 0.0 1.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain TSP_1 PF00090.14 EMC85808.1 - 4.2e-10 39.5 26.6 1.2e-06 28.5 6.3 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.1 EMC85808.1 - 6.6e-10 38.9 0.4 3.1e-07 30.4 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 EMC85808.1 - 0.0026 18.2 0.0 0.026 15.0 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 EMC85808.1 - 0.0079 16.3 0.0 0.0079 16.3 0.0 3.3 4 0 0 4 4 4 1 Immunoglobulin domain PTCRA PF15028.1 EMC85808.1 - 0.011 15.2 0.1 0.029 13.9 0.1 1.6 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Nucleoside_tran PF01733.13 EMC85809.1 - 5e-68 229.5 8.2 5e-68 229.5 5.7 2.0 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EMC85809.1 - 4.2e-05 22.4 34.8 0.00022 20.0 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cadherin PF00028.12 EMC85812.1 - 0 1437.3 42.2 5.2e-21 74.7 0.0 28.1 27 1 0 27 27 27 27 Cadherin domain Cadherin_2 PF08266.7 EMC85812.1 - 1.4e-21 75.8 0.0 0.21 11.1 0.0 14.3 15 0 0 15 15 15 5 Cadherin-like Rifin_STEVOR PF02009.11 EMC85812.1 - 1.4 8.5 0.4 2.3 7.7 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family SapB_1 PF05184.10 EMC85813.1 - 5.3e-20 70.7 11.6 5.5e-11 42.0 2.3 2.9 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 EMC85813.1 - 4.2e-13 49.0 9.8 2.2e-08 33.9 0.6 3.4 4 0 0 4 4 4 2 Saposin-like type B, region 2 Helicase_C_3 PF13625.1 EMC85813.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF1284 PF06935.6 EMC85813.1 - 9 6.5 7.0 1.1 9.4 0.7 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1284) SapB_2 PF03489.12 EMC85814.1 - 1.1e-47 159.5 44.8 1.3e-13 50.6 2.0 6.7 7 0 0 7 7 7 4 Saposin-like type B, region 2 SapB_1 PF05184.10 EMC85814.1 - 6.5e-44 146.9 25.2 9.8e-13 47.5 0.4 6.1 5 0 0 5 5 5 4 Saposin-like type B, region 1 SapA PF02199.10 EMC85814.1 - 3.1e-17 62.0 8.4 3.1e-17 62.0 5.9 3.6 3 0 0 3 3 3 2 Saposin A-type domain TLE_N PF03920.10 EMC85814.1 - 0.0026 17.5 2.5 0.2 11.5 0.4 2.7 2 1 0 2 2 2 2 Groucho/TLE N-terminal Q-rich domain DUF3895 PF13034.1 EMC85814.1 - 2.2 7.8 4.9 0.98 8.9 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) Sulfotransfer_1 PF00685.22 EMC85815.1 - 8.6e-40 136.6 0.0 1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC85815.1 - 0.00067 20.6 1.9 0.0011 19.8 1.2 1.6 1 1 0 1 1 1 1 Sulfotransferase family Pyr_redox_2 PF07992.9 EMC85816.1 - 1.7e-16 60.7 0.6 8.2e-06 25.8 0.2 3.7 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC85816.1 - 1.8e-08 34.6 0.6 3.2e-08 33.8 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC85816.1 - 4.6e-08 33.3 0.1 8.8e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC85816.1 - 5e-08 32.2 0.1 3e-06 26.3 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMC85816.1 - 2.5e-07 30.5 0.7 0.079 12.7 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 EMC85816.1 - 1.6e-06 27.2 2.1 0.013 14.4 0.1 3.1 2 1 1 3 3 3 3 FAD dependent oxidoreductase GIDA PF01134.17 EMC85816.1 - 0.00037 19.4 3.0 0.52 9.1 0.7 3.2 2 1 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 EMC85816.1 - 0.0016 16.9 0.4 0.19 10.1 0.1 2.8 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 EMC85816.1 - 0.003 16.5 0.3 0.036 12.9 0.1 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein DUF4147 PF13660.1 EMC85816.1 - 0.0096 15.0 0.4 0.015 14.4 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4147) Trp_halogenase PF04820.9 EMC85816.1 - 0.017 13.8 1.7 0.47 9.0 0.3 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EMC85816.1 - 0.055 13.7 0.4 0.1 12.8 0.3 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Histone PF00125.19 EMC85817.1 - 6.8e-22 77.3 0.0 1.6e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Macro PF01661.16 EMC85817.1 - 1.3e-18 66.9 0.1 2.5e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Macro domain CBFD_NFYB_HMF PF00808.18 EMC85817.1 - 0.01 15.9 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.15 EMC85817.1 - 0.029 14.3 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Clp amino terminal domain DUF1764 PF08576.5 EMC85817.1 - 0.26 12.0 5.1 0.24 12.1 1.9 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Collagen PF01391.13 EMC85818.1 - 2.1e-20 72.0 73.4 1.6e-08 33.9 27.6 4.4 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) DUF4140 PF13600.1 EMC85819.1 - 0.072 13.5 0.3 0.25 11.8 0.2 1.9 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 EMC85819.1 - 0.39 8.5 2.1 0.6 7.9 1.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2369 PF10179.4 EMC85820.1 - 5.1e-68 229.3 2.8 3.5e-63 213.4 1.1 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.16 EMC85820.1 - 2.2e-08 34.1 3.8 0.0008 19.4 0.1 4.6 5 0 0 5 5 5 3 Fibronectin type III domain CopK PF11525.3 EMC85820.1 - 0.17 11.5 0.8 15 5.3 0.0 2.9 3 0 0 3 3 3 0 Copper resistance protein K KH_1 PF00013.24 EMC85822.1 - 6.6e-35 118.5 6.1 8.6e-14 50.9 0.2 5.4 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 EMC85822.1 - 1.2e-24 85.4 9.3 5.9e-11 41.7 0.2 5.6 6 0 0 6 6 6 2 KH domain SAM_1 PF00536.25 EMC85822.1 - 1.9e-14 53.5 0.1 3.9e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC85822.1 - 2.2e-11 43.4 0.1 5.6e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SLS PF14611.1 EMC85822.1 - 8.4e-08 31.8 2.7 0.058 12.8 0.2 4.1 2 1 1 4 4 4 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EMC85822.1 - 0.0012 18.3 0.6 0.26 10.8 0.1 2.8 3 0 0 3 3 3 1 KH domain KH_4 PF13083.1 EMC85822.1 - 0.088 12.4 0.3 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 KH domain fn3 PF00041.16 EMC85823.1 - 1.3e-07 31.6 0.3 3.3e-07 30.3 0.1 1.8 2 1 0 2 2 2 1 Fibronectin type III domain DUF918 PF06033.6 EMC85823.1 - 0.091 12.2 0.6 0.29 10.6 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Drc1-Sld2 PF11719.3 EMC85824.1 - 0.014 14.4 2.2 0.014 14.4 1.5 3.3 2 1 1 3 3 3 0 DNA replication and checkpoint protein RhoGAP PF00620.22 EMC85825.1 - 1.2e-41 141.8 0.1 1.5e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain DAG_kinase_N PF14513.1 EMC85825.1 - 0.015 15.5 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus MFS_1 PF07690.11 EMC85826.1 - 9.3e-28 96.9 37.1 1.5e-16 60.0 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2046 PF09755.4 EMC85827.1 - 1.2e-134 448.1 46.7 1.4e-134 447.8 32.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) SLAM PF06214.6 EMC85827.1 - 0.11 12.4 2.0 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein ZU5 PF00791.15 EMC85828.1 - 2.5e-38 129.8 3.6 2.7e-35 120.1 0.1 2.5 2 0 0 2 2 2 2 ZU5 domain Death PF00531.17 EMC85828.1 - 7.5e-20 70.4 0.0 1.9e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Death domain Pkinase PF00069.20 EMC85829.1 - 1.3e-78 263.7 0.0 1.5e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85829.1 - 5e-35 120.8 0.0 6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC85829.1 - 0.00067 18.6 0.0 0.0021 17.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC85829.1 - 0.0031 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC85829.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EMC85829.1 - 0.011 14.8 0.0 0.029 13.4 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMC85829.1 - 0.054 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BTB PF00651.26 EMC85830.1 - 8e-29 99.8 5.9 9.1e-17 61.0 0.1 3.8 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.17 EMC85830.1 - 1.1e-23 83.3 0.0 2.6e-23 82.2 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC85830.1 - 6.2e-13 49.2 0.0 3.1e-12 47.0 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein CLAMP PF14769.1 EMC85831.1 - 1.2e-19 70.3 0.1 3.1e-19 68.9 0.0 1.6 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 BAR PF03114.13 EMC85831.1 - 0.016 14.7 0.1 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 BAR domain Sad1_UNC PF07738.8 EMC85831.1 - 0.062 13.1 0.0 0.88 9.3 0.0 2.1 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal ARID PF01388.16 EMC85832.1 - 7e-20 70.6 0.0 1.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Anillin PF08174.6 EMC85833.1 - 6e-28 97.6 0.0 1.5e-27 96.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EMC85833.1 - 5e-11 42.7 0.3 3.9e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EMC85833.1 - 0.00019 21.6 0.1 0.00044 20.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain HR1 PF02185.11 EMC85833.1 - 0.00024 20.7 0.4 0.001 18.7 0.2 2.0 1 0 0 1 1 1 1 Hr1 repeat PH_9 PF15410.1 EMC85833.1 - 0.0085 16.2 0.0 0.035 14.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain UvrD_C PF13361.1 EMC85834.1 - 0.013 15.0 6.4 0.019 14.4 4.5 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain MCP_N PF05581.7 EMC85834.1 - 0.021 14.9 0.2 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus ERM PF00769.14 EMC85834.1 - 0.024 14.1 14.2 0.035 13.6 9.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tropomyosin PF00261.15 EMC85834.1 - 0.037 13.1 20.4 0.061 12.4 14.1 1.2 1 0 0 1 1 1 0 Tropomyosin FUSC PF04632.7 EMC85834.1 - 0.076 11.4 3.6 0.1 11.0 2.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sugarporin_N PF11471.3 EMC85834.1 - 0.17 11.5 0.3 0.17 11.5 0.2 3.7 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension RBD-FIP PF09457.5 EMC85834.1 - 0.5 10.1 0.1 0.5 10.1 0.1 3.8 3 1 1 4 4 4 0 FIP domain Amidase PF01425.16 EMC85834.1 - 0.56 8.9 3.1 0.74 8.5 2.1 1.1 1 0 0 1 1 1 0 Amidase ATP-synt_E_2 PF08112.6 EMC85834.1 - 0.91 9.6 4.6 7 6.7 0.2 2.8 2 1 0 2 2 2 0 ATP synthase epsilon subunit Exonuc_VII_L PF02601.10 EMC85834.1 - 1 8.4 14.3 2.2 7.3 9.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 EMC85834.1 - 1.2 7.4 11.6 1 7.7 6.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) UPF0449 PF15136.1 EMC85834.1 - 1.5 9.0 9.1 1.6 8.9 2.3 2.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 FUSC-like PF12805.2 EMC85834.1 - 1.5 7.6 5.9 0.59 9.0 2.1 1.7 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS COG2 PF06148.6 EMC85834.1 - 2 8.3 9.8 1.1 9.1 2.1 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF904 PF06005.7 EMC85834.1 - 3.9 7.8 17.2 0.15 12.3 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Cache_2 PF08269.6 EMC85834.1 - 6.6 6.7 8.7 16 5.5 2.1 3.0 2 1 0 2 2 2 0 Cache domain DUF972 PF06156.8 EMC85834.1 - 6.9 7.0 12.1 9 6.6 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EMC85834.1 - 7.2 6.7 7.8 7.9 6.5 0.5 2.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Mit_KHE1 PF10173.4 EMC85834.1 - 9.2 6.0 7.1 2.4e+02 1.4 5.0 2.4 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF1875 PF08961.5 EMC85835.1 - 4.7e-128 425.6 13.1 5.4e-128 425.3 9.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) MIT PF04212.13 EMC85835.1 - 3.5e-05 23.5 1.1 0.00011 22.0 0.7 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DivIC PF04977.10 EMC85835.1 - 0.00051 19.4 2.5 0.00051 19.4 1.7 2.3 2 1 0 2 2 2 1 Septum formation initiator HALZ PF02183.13 EMC85835.1 - 0.0012 18.5 2.7 0.0012 18.5 1.9 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF972 PF06156.8 EMC85835.1 - 0.0047 17.2 1.2 0.0047 17.2 0.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF972) TPR_11 PF13414.1 EMC85835.1 - 0.0084 15.7 0.6 0.018 14.6 0.4 1.6 1 0 0 1 1 1 1 TPR repeat DUF904 PF06005.7 EMC85835.1 - 0.011 15.9 2.3 0.011 15.9 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF904) TPR_7 PF13176.1 EMC85835.1 - 0.064 13.0 0.2 0.21 11.4 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC85835.1 - 0.24 11.4 3.1 0.19 11.7 0.9 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat JmjC PF02373.17 EMC85836.1 - 2.4e-11 43.8 0.0 1.3e-10 41.5 0.0 2.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C3HC4_2 PF13923.1 EMC85836.1 - 2.1 8.4 6.5 5.8 7.0 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_3 PF07649.7 EMC85836.1 - 9.7 6.3 8.3 20 5.3 5.8 1.5 1 0 0 1 1 1 0 C1-like domain zf-C2H2 PF00096.21 EMC85837.1 - 7.9e-09 35.3 17.3 0.0032 17.7 0.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC85837.1 - 1.3e-08 34.6 13.3 0.0063 16.7 0.2 5.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-CHY PF05495.7 EMC85837.1 - 0.0025 17.9 3.4 0.008 16.3 2.3 1.9 1 0 0 1 1 1 1 CHY zinc finger zf-C2H2_4 PF13894.1 EMC85837.1 - 0.0048 17.1 17.4 1.1 9.7 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC85837.1 - 0.18 11.7 9.8 1.5 8.8 0.3 4.9 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.7 EMC85837.1 - 8.9 6.4 6.2 63 3.6 1.7 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain 7tm_1 PF00001.16 EMC85838.1 - 5.7e-30 104.3 4.8 8.2e-30 103.7 3.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC85838.1 - 3.7e-20 72.1 0.7 3.7e-20 72.1 0.5 2.6 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 EMC85838.1 - 1.5e-05 24.3 3.7 1.8e-05 24.0 2.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC85838.1 - 0.029 13.4 5.7 0.04 13.0 4.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv FCH PF00611.18 EMC85839.1 - 3.1e-22 78.5 4.8 4.5e-22 78.0 3.3 1.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain WW PF00397.21 EMC85839.1 - 9.9e-12 44.4 3.3 2e-11 43.5 2.3 1.5 1 0 0 1 1 1 1 WW domain Myosin_head PF00063.16 EMC85840.1 - 9e-269 893.2 1.4 9e-269 893.2 1.0 3.0 2 1 3 5 5 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EMC85840.1 - 1.1e-140 470.0 154.1 5.4e-136 454.5 61.5 2.5 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.14 EMC85840.1 - 2e-14 52.9 4.5 5.4e-14 51.5 3.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 EMC85840.1 - 0.00016 20.9 42.8 0.098 11.8 4.1 5.6 1 1 3 6 6 6 5 Reovirus sigma C capsid protein AAA_13 PF13166.1 EMC85840.1 - 0.002 16.7 107.4 0.036 12.5 22.8 4.0 1 1 2 3 3 3 2 AAA domain TMF_DNA_bd PF12329.3 EMC85840.1 - 0.0022 17.7 21.4 0.0022 17.7 14.8 11.0 4 2 7 12 12 10 5 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 EMC85840.1 - 0.0026 17.8 17.7 0.0026 17.8 12.3 6.8 2 1 5 7 7 7 2 Fibrinogen alpha/beta chain family IQ PF00612.22 EMC85840.1 - 0.003 17.0 0.2 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Filament PF00038.16 EMC85840.1 - 0.0039 16.6 127.3 0.0054 16.2 37.7 5.2 1 1 3 4 4 4 2 Intermediate filament protein IncA PF04156.9 EMC85840.1 - 0.0065 16.0 148.9 0.28 10.7 19.9 7.2 1 1 6 7 7 7 4 IncA protein DUF4537 PF15057.1 EMC85840.1 - 0.0075 16.0 0.4 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) GAS PF13851.1 EMC85840.1 - 0.089 11.9 141.7 1.6 7.8 16.1 6.2 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EMC85840.1 - 0.26 11.1 135.6 0.1 12.4 13.2 9.1 1 1 8 9 9 9 0 Afadin- and alpha -actinin-Binding Acyltransferase PF01553.16 EMC85841.1 - 1.4e-07 31.0 0.0 2.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kringle PF00051.13 EMC85842.1 - 5.7e-146 474.9 67.9 5.1e-31 106.5 4.4 5.5 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.21 EMC85842.1 - 6.5e-47 159.9 0.0 1.2e-46 159.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC85842.1 - 3.7e-09 36.2 0.0 6.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF3719 PF12516.3 EMC85842.1 - 2.6 7.6 14.4 24 4.6 0.1 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3719) Kringle PF00051.13 EMC85843.1 - 6.1e-149 484.4 72.4 1e-30 105.6 5.9 5.4 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.21 EMC85843.1 - 6.4e-63 212.2 0.1 1e-62 211.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 EMC85843.1 - 5.6e-10 38.8 1.2 5.6e-10 38.8 0.9 2.4 2 0 0 2 2 2 1 PAN domain DUF1986 PF09342.6 EMC85843.1 - 3.2e-09 36.4 0.0 6.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC85843.1 - 4.6e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain KduI PF04962.7 EMC85843.1 - 0.57 9.2 7.5 3.1 6.8 0.0 3.2 3 0 0 3 3 3 0 KduI/IolB family Sugar_tr PF00083.19 EMC85844.1 - 1.1e-29 103.2 15.4 1.1e-29 103.2 10.6 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC85844.1 - 3.4e-28 98.3 34.4 6.9e-22 77.6 10.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC85845.1 - 1.5e-29 102.8 9.1 2.1e-29 102.4 6.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC85845.1 - 2.9e-19 69.0 27.1 8.4e-15 54.3 6.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC85846.1 - 4.5e-33 114.5 12.3 6.6e-33 113.9 8.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC85846.1 - 1.3e-27 96.4 30.2 2.2e-25 89.1 11.9 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC85846.1 - 0.13 10.6 16.7 0.011 14.1 2.6 2.7 2 0 0 2 2 2 0 MFS/sugar transport protein CIMR PF00878.13 EMC85847.1 - 0 1256.4 85.6 3.2e-54 182.6 1.6 15.2 15 0 0 15 15 15 15 Cation-independent mannose-6-phosphate receptor repeat fn2 PF00040.14 EMC85847.1 - 9.2e-18 63.9 6.3 4.3e-17 61.8 4.4 2.3 1 0 0 1 1 1 1 Fibronectin type II domain Man-6-P_recep PF02157.10 EMC85847.1 - 2.5e-10 39.8 11.6 0.00013 21.0 0.1 5.7 6 0 0 6 6 6 2 Mannose-6-phosphate receptor 7tm_1 PF00001.16 EMC85848.1 - 9.1e-27 93.8 25.8 1.5e-26 93.1 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC85848.1 - 4.8e-08 32.4 21.5 4.8e-08 32.4 14.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ISK_Channel PF02060.10 EMC85848.1 - 0.079 12.5 1.5 0.59 9.7 0.0 2.5 2 1 1 3 3 3 0 Slow voltage-gated potassium channel 7TM_GPCR_Srbc PF10316.4 EMC85848.1 - 3.2 6.9 32.8 47 3.1 19.9 3.0 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc Serpentine_r_xa PF03383.10 EMC85848.1 - 7.5 6.2 29.0 0.021 14.6 10.4 2.8 2 1 1 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa CAF1 PF04857.15 EMC85849.1 - 1.8e-42 145.5 0.3 2.4e-42 145.1 0.2 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Thiolase_N PF00108.18 EMC85850.1 - 4e-85 284.9 1.9 6e-85 284.4 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC85850.1 - 1.3e-50 169.9 0.6 2.5e-50 169.0 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMC85850.1 - 0.00026 20.5 0.8 0.00026 20.5 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EMC85850.1 - 0.0015 18.5 0.1 0.0046 16.9 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Dodecin PF07311.7 EMC85850.1 - 0.0025 17.8 0.1 0.006 16.5 0.1 1.6 1 0 0 1 1 1 1 Dodecin AAA_13 PF13166.1 EMC85851.1 - 0.03 12.8 19.2 0.049 12.1 13.3 1.3 1 0 0 1 1 1 0 AAA domain DICT PF10069.4 EMC85851.1 - 0.14 11.6 6.4 0.51 9.8 4.4 2.1 1 1 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems ADIP PF11559.3 EMC85851.1 - 0.32 10.8 36.5 0.16 11.8 6.5 3.7 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 EMC85851.1 - 2.3 7.0 28.8 1.7 7.5 5.9 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EMC85851.1 - 5.5 6.7 12.1 0.13 12.0 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 EMC85851.1 - 7.6 6.2 27.9 0.38 10.4 8.0 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1515 PF07439.6 EMC85851.1 - 9.4 6.0 8.0 1.3 8.8 0.8 2.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) Sod_Fe_C PF02777.13 EMC85852.1 - 1.4e-44 150.2 0.1 2.6e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMC85852.1 - 4e-32 110.2 1.7 6.3e-32 109.6 1.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain fn3 PF00041.16 EMC85853.1 - 7.2e-34 115.7 5.2 2.3e-10 40.4 0.0 5.3 5 0 0 5 5 5 3 Fibronectin type III domain Interfer-bind PF09294.5 EMC85853.1 - 6.6e-07 29.3 0.1 0.081 12.9 0.2 3.8 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III SF3b10 PF07189.6 EMC85854.1 - 7.1e-39 131.4 0.1 7.8e-39 131.3 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.4 EMC85854.1 - 0.0073 15.0 0.3 0.008 14.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) SNARE PF05739.14 EMC85855.1 - 1.3e-14 53.5 1.2 1.3e-14 53.5 0.9 2.6 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EMC85855.1 - 1.3e-05 25.3 3.4 1.3e-05 25.3 2.4 2.5 2 1 0 2 2 2 1 Syntaxin Leu_zip PF15294.1 EMC85855.1 - 0.0062 15.6 1.5 0.0062 15.6 1.0 2.4 2 1 0 2 2 2 1 Leucine zipper Toprim_Crpt PF13342.1 EMC85855.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF1217 PF06748.7 EMC85855.1 - 0.034 14.2 0.1 0.09 12.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) MCPsignal PF00015.16 EMC85855.1 - 0.034 13.6 1.5 0.13 11.7 0.1 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FUN14 PF04930.10 EMC85855.1 - 0.085 13.1 0.5 0.52 10.6 0.0 2.3 2 1 0 2 2 2 0 FUN14 family Herpes_BLRF2 PF05812.7 EMC85855.1 - 0.12 12.2 2.1 0.18 11.6 1.1 1.8 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Spectrin PF00435.16 EMC85855.1 - 0.16 12.2 8.3 0.12 12.6 1.3 2.7 2 1 0 2 2 2 0 Spectrin repeat KxDL PF10241.4 EMC85855.1 - 0.16 11.8 4.0 0.25 11.2 0.8 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein HisKA_3 PF07730.8 EMC85855.1 - 0.21 11.9 2.6 3 8.2 0.2 3.3 2 2 1 3 3 3 0 Histidine kinase TMF_DNA_bd PF12329.3 EMC85855.1 - 0.25 11.1 3.5 0.21 11.4 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EMC85855.1 - 0.25 10.8 5.8 0.14 11.6 0.3 2.8 3 0 0 3 3 3 0 Septum formation initiator FlaC_arch PF05377.6 EMC85855.1 - 1.3 9.0 6.2 1.2 9.0 0.2 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DSPc PF00782.15 EMC85856.1 - 9.8e-14 51.0 0.0 1.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 EMC85856.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.7 EMC85856.1 - 0.063 12.7 0.0 0.098 12.0 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 EMC85856.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AlaDh_PNT_N PF05222.10 EMC85856.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain F-box PF00646.28 EMC85857.1 - 2.2e-07 30.3 1.1 6.2e-07 28.9 0.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMC85857.1 - 9.6e-07 28.4 0.2 2.8e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.13 EMC85857.1 - 0.017 15.4 3.3 0.017 15.4 2.3 5.0 6 1 1 7 7 7 0 TRAF-type zinc finger ANF_receptor PF01094.23 EMC85858.1 - 1.7e-91 306.6 0.0 2.4e-91 306.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 EMC85858.1 - 5.8e-71 238.5 27.5 8.2e-71 238.1 19.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GluR_Homer-bdg PF10606.4 EMC85858.1 - 2e-27 94.8 9.8 6e-27 93.2 6.8 1.9 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.9 EMC85858.1 - 4.7e-17 61.4 11.0 1.1e-16 60.2 7.6 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR AAA_34 PF13872.1 EMC85858.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Ras PF00071.17 EMC85859.1 - 8.6e-42 142.2 0.0 1e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC85859.1 - 1e-18 67.9 0.0 1.4e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC85859.1 - 2.1e-09 36.8 0.0 2.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC85859.1 - 7e-07 28.6 0.0 8.2e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EMC85859.1 - 0.00027 21.0 0.0 0.0021 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EMC85859.1 - 0.00067 19.1 0.0 0.02 14.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EMC85859.1 - 0.0014 18.3 0.1 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EMC85859.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EMC85859.1 - 0.0081 15.7 0.0 1.2 8.5 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EMC85859.1 - 0.011 15.1 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EMC85859.1 - 0.049 13.6 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EMC85859.1 - 0.061 12.7 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 EMC85859.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EMC85859.1 - 0.079 12.5 0.1 0.34 10.4 0.0 2.0 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 EMC85859.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 EMC85859.1 - 0.14 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C2 PF00648.16 EMC85860.1 - 1.4e-08 34.1 0.1 7.8e-08 31.6 0.0 2.0 2 0 0 2 2 2 1 Calpain family cysteine protease Globin PF00042.17 EMC85861.1 - 1.7e-05 25.1 0.0 0.0005 20.3 0.0 2.3 2 0 0 2 2 2 1 Globin IQ PF00612.22 EMC85861.1 - 0.0075 15.8 0.1 0.015 14.8 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif SAM_1 PF00536.25 EMC85862.1 - 6.3e-08 32.6 0.0 7.3e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC85862.1 - 9.1e-07 28.6 0.0 9.3e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 EMC85862.1 - 0.027 14.2 0.1 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) SLY PF12485.3 EMC85863.1 - 4.1e-46 157.0 14.5 4.1e-46 157.0 10.1 3.2 4 0 0 4 4 4 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.12 EMC85863.1 - 1.7e-18 66.1 0.0 7.4e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC85863.1 - 7.5e-17 61.2 0.0 4.5e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EMC85863.1 - 7.4e-06 25.3 0.0 2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC85863.1 - 0.0084 15.4 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Sulfotransfer_2 PF03567.9 EMC85864.1 - 2.2e-32 112.7 1.1 2.9e-32 112.3 0.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 EMC85864.1 - 2e-08 33.2 0.3 2.8e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase CUE PF02845.11 EMC85865.1 - 2e-09 36.7 0.1 3.6e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 CUE domain zf-RanBP PF00641.13 EMC85865.1 - 1.1e-05 24.3 2.0 2.7e-05 23.1 1.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DivIC PF04977.10 EMC85865.1 - 0.014 14.8 2.9 0.093 12.2 1.6 2.1 2 0 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 EMC85865.1 - 0.057 13.0 1.7 0.09 12.4 1.2 1.2 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EMC85865.1 - 0.15 11.6 4.9 0.26 10.8 3.4 1.3 1 0 0 1 1 1 0 IncA protein RNase_Zc3h12a PF11977.3 EMC85867.1 - 8.5e-52 175.0 0.0 1.5e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH PF00642.19 EMC85867.1 - 0.1 12.3 7.2 0.28 10.9 3.7 2.5 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMC85867.1 - 0.32 11.0 8.4 0.95 9.5 5.8 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Omega-toxin PF06357.6 EMC85867.1 - 0.74 9.4 4.7 1.9 8.1 3.3 1.6 1 0 0 1 1 1 0 Omega-atracotoxin Pro_isomerase PF00160.16 EMC85868.1 - 9e-38 129.9 0.2 1.9e-37 128.8 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EMC85868.1 - 5e-18 64.4 0.0 1e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC85868.1 - 5e-12 45.6 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85868.1 - 4.4e-09 36.0 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EMC85870.1 - 1.2e-58 198.3 1.5 2.7e-38 131.5 0.0 3.1 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85870.1 - 2.6e-28 98.8 0.0 2.3e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase UBA PF00627.26 EMC85870.1 - 1e-08 34.7 1.5 2.6e-08 33.4 0.3 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Kinase-like PF14531.1 EMC85870.1 - 0.00066 18.7 0.1 0.0025 16.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC85870.1 - 0.0027 17.4 0.4 0.017 14.8 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EMC85870.1 - 0.02 15.3 1.0 0.02 15.3 0.7 2.3 2 0 0 2 2 1 0 Protein kinase C terminal domain UBA_3 PF09288.5 EMC85870.1 - 0.041 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Pox_ser-thr_kin PF05445.6 EMC85870.1 - 0.043 12.6 0.1 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YjcZ PF13990.1 EMC85870.1 - 0.044 12.8 0.5 0.079 12.0 0.4 1.3 1 0 0 1 1 1 0 YjcZ-like protein DUF2015 PF09435.5 EMC85870.1 - 0.072 12.8 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Seadorna_VP7 PF07387.6 EMC85870.1 - 0.21 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PCMT PF01135.14 EMC85871.1 - 3.9e-76 255.2 0.0 4.4e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EMC85871.1 - 1.1e-08 34.8 0.0 1.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC85871.1 - 2.2e-08 34.6 0.0 3.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC85871.1 - 1.2e-05 25.7 0.0 3.8e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMC85871.1 - 9.6e-05 21.5 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EMC85871.1 - 0.00012 21.3 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EMC85871.1 - 0.00015 21.4 0.0 0.00046 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EMC85871.1 - 0.00025 20.6 0.0 0.00029 20.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EMC85871.1 - 0.002 18.1 0.0 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC85871.1 - 0.0045 17.3 0.0 0.0071 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC85871.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EMC85871.1 - 0.028 14.3 0.0 0.047 13.6 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 EMC85871.1 - 0.044 12.7 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 EMC85871.1 - 0.053 12.4 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_32 PF13679.1 EMC85871.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ldl_recept_a PF00057.13 EMC85872.1 - 2.2e-06 27.4 12.0 2.2e-06 27.4 8.3 1.6 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Big_3_4 PF13754.1 EMC85872.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) DUF4625 PF15418.1 EMC85872.1 - 0.0057 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) REJ PF02010.10 EMC85872.1 - 0.026 12.8 0.0 0.051 11.8 0.0 1.4 1 0 0 1 1 1 0 REJ domain PP1_inhibitor PF05361.7 EMC85873.1 - 2.6e-17 62.8 0.3 2.7e-17 62.7 0.2 1.0 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Nitroreductase PF00881.19 EMC85874.1 - 1.4e-22 80.2 0.0 2.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family RhoGEF PF00621.15 EMC85875.1 - 2e-45 154.8 3.7 2.6e-45 154.4 1.0 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EMC85875.1 - 0.012 15.7 0.1 0.064 13.4 0.1 2.3 1 0 0 1 1 1 0 PH domain PH_10 PF15411.1 EMC85875.1 - 0.033 14.3 0.2 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain FTHFS PF01268.14 EMC85876.1 - 1.7e-239 795.4 1.0 2.1e-239 795.1 0.7 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EMC85876.1 - 1.2e-23 83.0 0.4 7.2e-23 80.4 0.1 2.4 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMC85876.1 - 2.4e-16 59.8 0.1 1e-15 57.7 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Alba PF01918.16 EMC85876.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.7 1 0 0 1 1 1 0 Alba WSK PF03832.8 EMC85877.1 - 8e-22 76.2 47.9 6.3e-12 44.6 2.0 6.4 5 0 0 5 5 5 3 WSK motif BTB PF00651.26 EMC85878.1 - 2.2e-19 69.4 0.2 4.6e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC85878.1 - 7e-13 48.1 22.3 8e-05 22.7 1.7 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC85878.1 - 7.9e-13 47.9 32.7 0.00052 20.1 1.1 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 EMC85878.1 - 2.3e-08 33.9 21.8 0.13 12.4 0.6 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMC85878.1 - 3.9e-08 33.0 29.2 0.004 17.3 0.9 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC85878.1 - 5.5e-08 32.7 17.4 0.023 14.8 0.1 4.7 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC85878.1 - 0.0043 16.8 22.6 1.7 8.6 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC85878.1 - 0.026 14.1 19.5 0.25 11.0 0.3 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EMC85878.1 - 0.11 12.6 17.3 4.3 7.5 0.2 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.11 EMC85878.1 - 3.5 7.8 15.1 6.4 6.9 0.1 4.3 4 0 0 4 4 4 0 C1 domain C1_4 PF07975.7 EMC85878.1 - 3.7 7.6 14.3 4.1 7.4 2.9 3.9 3 1 1 4 4 4 0 TFIIH C1-like domain Ribosomal_L37ae PF01780.14 EMC85878.1 - 7.3 6.5 10.4 17 5.3 0.0 3.5 3 1 1 4 4 4 0 Ribosomal L37ae protein family DUF155 PF02582.9 EMC85879.1 - 8.3e-50 169.1 3.7 1.1e-49 168.7 2.6 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF89 PF01937.14 EMC85880.1 - 2.6e-121 404.7 0.5 3e-121 404.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Oest_recep PF02159.10 EMC85882.1 - 2.1e-54 183.4 8.2 2.1e-54 183.4 5.7 2.4 3 0 0 3 3 3 1 Oestrogen receptor zf-C4 PF00105.13 EMC85882.1 - 8.4e-31 106.0 14.2 1.5e-30 105.2 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC85882.1 - 8.8e-29 100.0 1.6 1.5e-28 99.3 1.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ESR1_C PF12743.2 EMC85882.1 - 8.7e-20 69.9 4.7 8.7e-20 69.9 3.2 1.9 2 0 0 2 2 2 1 Oestrogen-type nuclear receptor final C-terminal Myc_target_1 PF15179.1 EMC85883.1 - 3.9e-63 212.6 14.5 3.2e-34 118.2 2.7 2.0 1 1 1 2 2 2 2 Myc target protein 1 Hormone_2 PF00123.15 EMC85884.1 - 4.4e-23 80.7 6.5 1.1e-11 44.3 0.2 2.8 3 0 0 3 3 3 2 Peptide hormone F-box PF00646.28 EMC85885.1 - 4.5e-07 29.3 0.0 8.6e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain IBR PF01485.16 EMC85885.1 - 5.2e-07 29.4 11.1 1.1e-06 28.3 7.7 1.5 1 0 0 1 1 1 1 IBR domain F-box-like PF12937.2 EMC85885.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF1663 PF07909.6 EMC85885.1 - 0.087 11.3 0.1 0.14 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) RF-1 PF00472.15 EMC85886.1 - 6.4e-40 135.5 4.6 7.7e-40 135.2 2.5 1.6 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EMC85886.1 - 3.7e-35 120.1 0.9 3.7e-35 120.1 0.6 2.2 2 0 0 2 2 2 1 PCRF domain RGS PF00615.14 EMC85887.1 - 4.9e-36 123.4 1.6 6.9e-36 122.9 1.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4226 PF10774.4 EMC85887.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) 7tm_1 PF00001.16 EMC85888.1 - 1.4e-62 211.1 24.7 1.6e-62 210.9 17.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC85888.1 - 5e-09 35.6 14.6 6.2e-09 35.3 10.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Herpes_US9 PF06072.6 EMC85888.1 - 5.2 6.9 10.0 0.1 12.4 0.5 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF1170 PF06663.8 EMC85889.1 - 2.2e-62 210.3 3.2 6.4e-62 208.8 1.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 EMC85889.1 - 4.9e-43 145.0 0.4 1.6e-42 143.4 0.1 2.2 2 0 0 2 2 1 1 Connector enhancer of kinase suppressor of ras PH PF00169.24 EMC85889.1 - 2.9e-13 49.9 0.8 2.9e-13 49.9 0.5 2.6 3 0 0 3 3 3 1 PH domain SAM_1 PF00536.25 EMC85889.1 - 5.9e-12 45.5 1.0 1.2e-11 44.5 0.2 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 EMC85889.1 - 1.6e-09 37.8 0.0 3.5e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 EMC85889.1 - 2.6e-08 33.5 0.5 9.2e-08 31.8 0.3 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.1 EMC85889.1 - 0.0023 17.7 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain TMEM154 PF15102.1 EMC85889.1 - 0.012 15.3 0.1 0.012 15.3 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF3753 PF12575.3 EMC85889.1 - 0.021 14.5 4.0 0.07 12.9 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) PH_11 PF15413.1 EMC85889.1 - 0.031 14.5 6.4 0.18 12.0 4.4 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Orbi_NS3 PF01616.11 EMC85889.1 - 0.044 12.7 0.1 0.097 11.6 0.1 1.5 1 0 0 1 1 1 0 Orbivirus NS3 TatC PF00902.13 EMC85889.1 - 0.047 13.0 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF912 PF06024.7 EMC85889.1 - 0.064 13.3 1.6 0.086 12.8 0.1 1.9 2 0 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PH_9 PF15410.1 EMC85889.1 - 0.18 11.9 4.2 4.8 7.3 1.2 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain plasmid_Toxin PF12703.2 EMC85890.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system UPF0542 PF15086.1 EMC85890.1 - 0.71 9.6 0.0 0.71 9.6 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0542 RrnaAD PF00398.15 EMC85891.1 - 3.1e-41 141.1 0.0 3.6e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMC85891.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PMP22_Claudin PF00822.15 EMC85892.1 - 4.5e-27 94.7 8.8 5.5e-27 94.4 6.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC85892.1 - 7.5e-11 42.0 8.1 1.3e-10 41.2 5.5 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EMC85892.1 - 0.003 16.8 0.8 0.0046 16.2 0.2 1.6 1 1 0 1 1 1 1 Clc-like DUF998 PF06197.8 EMC85892.1 - 0.32 10.2 10.8 0.12 11.6 1.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF998) CD20 PF04103.10 EMC85892.1 - 0.38 10.6 12.3 0.25 11.2 3.3 3.1 2 1 1 3 3 3 0 CD20-like family DUF4131 PF13567.1 EMC85892.1 - 3.3 7.0 5.0 0.47 9.8 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) NAD_binding_6 PF08030.7 EMC85893.1 - 2.9e-29 102.0 0.2 3.6e-28 98.4 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMC85893.1 - 5.7e-22 78.1 1.3 1.3e-21 76.9 0.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMC85893.1 - 4.7e-20 71.4 0.1 1.1e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 EMC85893.1 - 9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF3518 PF12031.3 EMC85895.1 - 5.2e-150 497.3 0.1 9.3e-150 496.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) ARID PF01388.16 EMC85895.1 - 9.9e-28 95.8 0.0 2.1e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PV-1 PF06637.6 EMC85895.1 - 3 6.3 3.7 5 5.5 2.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF1358 PF07096.6 EMC85896.1 - 7.5e-39 132.2 0.9 8.5e-39 132.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) NifQ PF04891.7 EMC85896.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 NifQ Peptidase_C4 PF00863.14 EMC85896.1 - 0.062 12.2 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C4 zf-DHHC PF01529.15 EMC85897.1 - 2e-37 128.2 1.9 2e-37 128.2 1.3 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase BAR_3_WASP_bdg PF10456.4 EMC85898.1 - 1.6e-110 368.0 0.5 2.1e-110 367.6 0.3 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 EMC85898.1 - 2.2e-23 82.2 0.2 4.5e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 EMC85898.1 - 2.5e-09 36.3 0.3 7.3e-09 34.8 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC85898.1 - 3.7e-09 36.0 0.2 1.4e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC85898.1 - 4.1e-08 32.5 0.0 9.1e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EMC85898.1 - 0.0021 17.3 0.1 0.53 9.4 0.1 2.4 1 1 1 2 2 2 2 Vps5 C terminal like Syja_N PF02383.13 EMC85900.1 - 7.2e-77 258.2 0.0 1.3e-76 257.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.6 EMC85900.1 - 5.6e-54 181.6 0.4 1.9e-53 179.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.18 EMC85900.1 - 2.8e-30 106.0 0.1 6.1e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_6 PF14259.1 EMC85900.1 - 0.00016 21.6 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC85900.1 - 0.0012 18.7 0.0 0.0034 17.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC85900.1 - 0.0012 18.3 0.0 0.0041 16.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF521 PF04412.8 EMC85900.1 - 0.19 10.2 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Tbf5 PF06331.7 EMC85901.1 - 1.1e-29 102.0 0.2 1.2e-29 101.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 MIG-14_Wnt-bd PF06664.7 EMC85902.1 - 6.2e-118 392.9 32.2 6.2e-118 392.9 22.3 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Tctex-1 PF03645.8 EMC85903.1 - 2.7e-37 126.6 0.8 3e-37 126.5 0.5 1.0 1 0 0 1 1 1 1 Tctex-1 family FYVE_2 PF02318.11 EMC85904.1 - 3.5e-18 65.6 12.7 3.5e-18 65.6 8.8 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger C2 PF00168.25 EMC85904.1 - 3.3e-17 62.1 0.0 9.1e-15 54.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain ERM PF00769.14 EMC85905.1 - 5.5e-72 242.2 40.1 5.5e-72 242.2 27.8 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.5 EMC85905.1 - 7.1e-34 115.8 0.0 2.2e-33 114.3 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 EMC85905.1 - 5.3e-25 88.0 0.2 5.3e-25 88.0 0.2 3.5 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.5 EMC85905.1 - 8.7e-19 67.3 3.2 2e-18 66.2 0.1 2.9 3 0 0 3 3 3 1 FERM N-terminal domain DUF3650 PF12368.3 EMC85905.1 - 0.099 12.1 0.2 0.099 12.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) RhoGAP PF00620.22 EMC85906.1 - 1.2e-12 47.6 0.7 1.9e-12 47.0 0.5 1.3 1 0 0 1 1 1 1 RhoGAP domain RhoGAP PF00620.22 EMC85907.1 - 5.9e-38 129.8 1.5 1.2e-37 128.8 0.8 1.8 2 0 0 2 2 2 1 RhoGAP domain Radial_spoke_3 PF06098.6 EMC85908.1 - 1.5e-118 395.0 9.7 1.6e-118 394.9 6.7 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 FBPase PF00316.15 EMC85908.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase SET PF00856.23 EMC85909.1 - 0.0015 18.8 0.1 1.9 8.7 0.0 2.2 1 1 1 2 2 2 2 SET domain zf-C2H2 PF00096.21 EMC85909.1 - 0.31 11.4 7.9 0.6 10.5 0.5 3.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC85909.1 - 0.7 10.3 6.7 0.21 12.0 1.0 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC85910.1 - 1.4e-16 59.6 7.8 2.9e-09 36.3 0.2 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EMC85910.1 - 0.0023 18.1 6.4 0.38 11.1 0.1 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-Di19 PF05605.7 EMC85910.1 - 0.014 15.4 3.8 0.2 11.8 0.4 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EMC85910.1 - 0.045 13.7 2.6 1.5 8.9 0.4 2.5 2 0 0 2 2 2 0 zinc-finger zinc-ribbons_6 PF07191.7 EMC85910.1 - 0.065 13.0 3.4 0.2 11.4 0.3 2.3 2 1 0 2 2 2 0 zinc-ribbons DNA_RNApol_7kD PF03604.8 EMC85910.1 - 0.075 12.5 1.5 6 6.4 0.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Nairovirus_M PF07948.6 EMC85910.1 - 0.078 11.0 2.8 0.64 8.0 0.2 2.1 2 0 0 2 2 2 0 Nairovirus M polyprotein-like zf-C2H2 PF00096.21 EMC85910.1 - 0.092 13.1 16.5 1 9.8 0.0 4.0 4 1 0 4 4 3 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 EMC85910.1 - 0.11 12.3 0.9 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain DZR PF12773.2 EMC85910.1 - 0.12 12.2 1.8 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon Sgf11 PF08209.6 EMC85910.1 - 0.23 10.7 2.8 3.6 6.9 0.3 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_5 PF13719.1 EMC85910.1 - 0.24 11.0 4.7 0.56 9.8 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EMC85910.1 - 0.24 11.3 7.1 9.5 6.2 0.2 3.6 4 0 0 4 4 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EMC85910.1 - 0.26 11.2 3.1 16 5.5 0.2 3.0 3 1 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 EMC85910.1 - 0.45 10.2 5.1 0.66 9.7 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Evr1_Alr PF04777.8 EMC85910.1 - 0.8 9.6 6.8 13 5.8 0.5 3.0 2 1 1 3 3 3 0 Erv1 / Alr family FYVE PF01363.16 EMC85910.1 - 1.4 8.8 7.5 4.5 7.2 0.6 2.4 2 1 0 2 2 2 0 FYVE zinc finger zf-FPG_IleRS PF06827.9 EMC85910.1 - 1.6 8.4 6.5 7.3 6.3 0.4 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-tcix PF14952.1 EMC85910.1 - 2 7.7 5.5 0.56 9.5 0.1 2.5 2 1 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF329 PF03884.9 EMC85910.1 - 4 7.0 10.2 1.7 8.2 0.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zf-C2H2_jaz PF12171.3 EMC85910.1 - 4.2 7.6 12.2 1.7 8.9 0.1 4.1 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMC85910.1 - 5.2 7.6 14.6 2.7 8.5 1.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger DUF164 PF02591.10 EMC85910.1 - 5.4 6.9 6.0 24 4.8 0.8 3.1 2 1 1 3 3 3 0 Putative zinc ribbon domain LTV PF04180.9 EMC85911.1 - 9.2e-104 348.2 22.1 1.2e-103 347.8 15.3 1.2 1 0 0 1 1 1 1 Low temperature viability protein RPEL PF02755.10 EMC85912.1 - 1.8e-28 97.0 29.0 1.1e-09 37.3 0.4 4.7 5 0 0 5 5 5 4 RPEL repeat Alpha_L_fucos PF01120.12 EMC85913.1 - 5.7e-98 328.0 0.1 6.8e-98 327.7 0.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Peroxin-3 PF04882.7 EMC85914.1 - 3.1e-102 342.4 2.4 5.7e-79 265.8 0.1 2.0 1 1 1 2 2 2 2 Peroxin-3 DUF4174 PF13778.1 EMC85914.1 - 0.019 15.0 0.1 0.48 10.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4174) Ion_trans PF00520.26 EMC85914.1 - 0.074 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein dCMP_cyt_deam_1 PF00383.17 EMC85915.1 - 5.7e-20 70.8 1.2 8.4e-20 70.3 0.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMC85915.1 - 0.00013 21.8 3.6 0.0017 18.1 2.5 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 EMC85915.1 - 0.0024 17.5 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Far-17a_AIG1 PF04750.9 EMC85916.1 - 9.9e-74 246.8 12.7 1.1e-73 246.6 8.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein PrgI PF12666.2 EMC85916.1 - 2.8 8.1 6.1 0.8 9.8 0.3 2.7 1 1 1 2 2 2 0 PrgI family protein zf-C2H2 PF00096.21 EMC85917.1 - 1.8e-17 62.5 28.7 0.00018 21.6 1.1 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC85917.1 - 1.7e-12 46.9 37.4 5.3e-07 29.6 0.7 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC85917.1 - 4.2e-12 45.8 22.6 0.00065 19.7 0.8 5.1 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMC85917.1 - 3.9e-08 33.0 23.9 0.02 15.1 0.3 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EMC85917.1 - 4.8e-05 23.4 25.4 0.0071 16.5 1.8 5.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC85917.1 - 0.51 10.4 18.5 0.084 12.9 2.1 4.2 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) 7tm_2 PF00002.19 EMC85918.1 - 1.9e-49 167.9 17.0 1.9e-49 167.9 11.8 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) CUB PF00431.15 EMC85918.1 - 2e-24 85.8 0.0 4.8e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 CUB domain GPS PF01825.16 EMC85918.1 - 6.4e-17 61.3 0.6 2.4e-16 59.5 0.4 2.1 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Pentaxin PF00354.12 EMC85918.1 - 1.7e-10 40.6 1.9 1.2e-09 37.8 0.1 2.8 3 0 0 3 3 3 1 Pentaxin family Laminin_G_3 PF13385.1 EMC85918.1 - 0.0014 18.9 0.1 0.0038 17.4 0.1 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF605 PF04652.11 EMC85919.1 - 3.5e-83 280.1 6.5 1.2e-61 209.1 0.4 2.0 1 1 1 2 2 2 2 Vta1 like TFIIA PF03153.8 EMC85919.1 - 0.15 11.9 1.9 0.2 11.5 1.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin_CCC PF10582.4 EMC85920.1 - 3.4e-20 71.6 6.1 9.4e-20 70.2 4.2 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin PF00029.14 EMC85920.1 - 3.2e-09 36.8 0.1 3.2e-09 36.8 0.1 2.5 2 1 1 3 3 3 1 Connexin DUF4418 PF14387.1 EMC85920.1 - 1.8 8.3 8.1 2.8 7.7 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) DUF3816 PF12822.2 EMC85920.1 - 3.3 7.5 9.6 4.9 7.0 6.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) 7tm_1 PF00001.16 EMC85921.1 - 7.5e-54 182.5 14.1 1e-53 182.1 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC85921.1 - 2.2e-10 40.1 9.3 2.2e-10 40.1 6.4 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 EMC85921.1 - 3.5e-07 29.6 13.0 5e-07 29.1 9.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 EMC85921.1 - 0.092 11.8 16.6 0.19 10.8 10.5 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.4 EMC85921.1 - 0.16 11.0 14.8 0.013 14.6 6.0 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx HECA PF15353.1 EMC85922.1 - 5.2e-39 132.2 8.5 1.1e-38 131.2 5.9 1.6 1 0 0 1 1 1 1 Headcase protein family homologue RecR PF02132.10 EMC85922.1 - 0.045 13.2 3.2 1.7 8.1 0.1 2.9 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.1 EMC85922.1 - 0.31 10.3 5.9 6.3 6.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMC85922.1 - 2.5 7.7 10.8 2.7 7.5 0.5 3.5 3 0 0 3 3 3 0 zinc-ribbon domain CTDII PF01556.13 EMC85923.1 - 1.6e-25 88.7 0.5 1.9e-21 75.7 0.0 3.1 2 1 0 2 2 2 2 DnaJ C terminal domain F5_F8_type_C PF00754.20 EMC85924.1 - 2.5e-17 62.9 2.3 2.8e-17 62.7 1.6 1.0 1 0 0 1 1 1 1 F5/8 type C domain Vps55 PF04133.9 EMC85926.1 - 0.1 12.3 0.1 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting 55 RVT_1 PF00078.22 EMC85927.1 - 0.068 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TPK_catalytic PF04263.11 EMC85928.1 - 8.9e-33 112.5 0.0 1.1e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EMC85928.1 - 2.3e-24 84.8 0.3 3.4e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SecE PF00584.15 EMC85929.1 - 1.7e-15 56.3 0.1 2.1e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TPR_11 PF13414.1 EMC85930.1 - 0.00021 20.8 6.7 0.0017 17.9 0.0 3.9 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 EMC85930.1 - 0.83 9.3 4.8 46 3.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC85930.1 - 1.6 8.8 13.1 1.4 8.9 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EMC85931.1 - 1.1e-88 296.7 0.0 1.6e-88 296.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 EMC85931.1 - 3.6e-60 200.8 2.4 2.2e-30 104.9 1.5 2.5 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.1 EMC85931.1 - 6.7e-55 184.2 80.9 1.3e-47 160.6 17.6 4.0 2 1 2 4 4 4 2 Growth factor receptor domain IV Pkinase PF00069.20 EMC85931.1 - 5.4e-43 147.0 0.0 8.1e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 EMC85931.1 - 1.7e-35 121.8 88.9 3.2e-30 104.7 29.5 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.18 EMC85931.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC85931.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DBP PF12361.3 EMC85931.1 - 0.38 10.2 0.5 0.61 9.5 0.3 1.2 1 0 0 1 1 1 0 Duffy-antigen binding protein WBP-1 PF11669.3 EMC85932.1 - 0.00021 21.3 3.6 0.00021 21.3 2.5 2.4 2 0 0 2 2 2 1 WW domain-binding protein 1 TMEM52 PF14979.1 EMC85932.1 - 0.062 13.2 10.6 0.061 13.2 1.2 2.1 2 0 0 2 2 2 0 Transmembrane 52 DUF3483 PF11982.3 EMC85932.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) CX PF01705.14 EMC85932.1 - 0.16 11.9 5.9 0.36 10.8 4.1 1.6 1 0 0 1 1 1 0 CX module Biliv-reduc_cat PF09166.5 EMC85933.1 - 9.8e-54 180.3 0.1 1.5e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.17 EMC85933.1 - 1.5e-17 64.2 0.4 3.9e-17 62.8 0.2 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EMC85933.1 - 0.086 13.1 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Coa1 PF08695.5 EMC85934.1 - 2.6e-20 72.0 0.0 3e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.6 EMC85934.1 - 0.0089 15.6 0.0 0.012 15.2 0.0 1.3 1 1 0 1 1 1 1 TIM21 Pkinase PF00069.20 EMC85935.1 - 1e-64 218.2 0.0 1.6e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC85935.1 - 4.9e-32 111.0 0.1 7.2e-32 110.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC85935.1 - 7.4e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC85935.1 - 0.00017 20.7 0.0 0.00034 19.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC85935.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EMC85935.1 - 0.021 14.1 0.2 0.042 13.1 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EMC85935.1 - 0.053 13.0 0.1 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SPOUT_MTase_2 PF14419.1 EMC85935.1 - 0.055 12.6 0.1 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Pox_ser-thr_kin PF05445.6 EMC85935.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HECT PF00632.20 EMC85936.1 - 2.5e-93 312.7 0.0 3.9e-93 312.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMC85936.1 - 5.2e-17 61.3 0.4 1.7e-09 37.3 0.4 2.8 2 0 0 2 2 2 2 WW domain C2 PF00168.25 EMC85936.1 - 2.2e-09 36.9 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Keratin_B2_2 PF13885.1 EMC85936.1 - 0.21 11.3 22.3 0.76 9.5 15.5 2.0 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein RFXA_RFXANK_bdg PF15289.1 EMC85936.1 - 0.95 9.6 4.3 0.63 10.2 0.0 2.8 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain PDEase_I PF00233.14 EMC85939.1 - 1.6e-96 322.6 5.0 2.9e-96 321.8 3.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 EMC85939.1 - 2.6e-28 97.6 0.0 2.6e-28 97.6 0.0 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal TEX19 PF15553.1 EMC85939.1 - 0.96 9.2 5.5 2 8.2 3.8 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Aa_trans PF01490.13 EMC85940.1 - 1.8e-70 237.4 25.9 2e-70 237.3 17.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Kua-UEV1_localn PF10520.4 EMC85940.1 - 0.18 11.4 4.4 0.22 11.1 2.1 1.9 1 1 1 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain CABIT PF12736.2 EMC85941.1 - 7.5e-90 300.4 3.6 4e-50 170.2 0.7 2.2 2 0 0 2 2 2 2 Cell-cycle sustaining, positive selection, DUF1966 PF09260.6 EMC85941.1 - 0.075 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) DUF781 PF05612.7 EMC85942.1 - 1.9e-105 352.4 0.1 2.2e-105 352.2 0.1 1.0 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) DUF3733 PF12534.3 EMC85942.1 - 0.03 13.6 0.0 0.089 12.1 0.0 1.8 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 DUF3166 PF11365.3 EMC85943.1 - 3.7e-68 226.0 46.0 3.2e-43 146.1 1.3 5.4 5 2 0 5 5 5 2 Protein of unknown function (DUF3166) TSC22 PF01166.13 EMC85943.1 - 5.8e-05 22.9 44.1 0.004 17.0 0.2 7.4 7 1 0 7 7 7 4 TSC-22/dip/bun family DUF2968 PF11180.3 EMC85943.1 - 0.00015 21.2 7.0 0.00015 21.2 4.8 4.4 3 2 1 4 4 4 1 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.7 EMC85943.1 - 0.00038 20.1 49.2 0.036 13.8 4.4 5.3 3 2 3 6 6 6 3 TPR/MLP1/MLP2-like protein Halo_GVPC PF05465.8 EMC85943.1 - 0.0076 16.1 0.2 0.023 14.6 0.2 1.9 1 0 0 1 1 1 1 Halobacterial gas vesicle protein C (GVPC) repeat HALZ PF02183.13 EMC85943.1 - 0.0084 15.8 2.7 0.0084 15.8 1.9 6.9 6 1 0 6 6 6 1 Homeobox associated leucine zipper DUF972 PF06156.8 EMC85943.1 - 0.021 15.1 55.2 0.45 10.8 3.8 6.8 4 2 3 7 7 7 0 Protein of unknown function (DUF972) DUF2207 PF09972.4 EMC85943.1 - 0.06 11.9 0.1 0.06 11.9 0.1 2.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DivIC PF04977.10 EMC85943.1 - 0.16 11.4 57.8 0.29 10.6 0.1 9.0 7 3 1 8 8 8 0 Septum formation initiator APG6 PF04111.7 EMC85943.1 - 0.6 9.0 60.2 0.58 9.1 0.0 4.6 1 1 3 4 4 4 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 EMC85943.1 - 0.78 8.8 4.7 8.5 5.4 0.4 2.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Herpes_BLRF2 PF05812.7 EMC85943.1 - 2 8.2 31.2 2.5 7.9 0.0 5.3 3 1 1 4 4 3 0 Herpesvirus BLRF2 protein DUF4482 PF14818.1 EMC85944.1 - 3.4e-29 102.3 40.8 2.1e-22 80.3 10.4 4.7 4 1 1 5 5 5 2 Domain of unknown function (DUF4482) ECH PF00378.15 EMC85945.1 - 3e-38 131.3 0.0 3.9e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4478 PF14793.1 EMC85945.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) WWE PF02825.15 EMC85946.1 - 1.9e-13 49.6 0.9 3.6e-13 48.7 0.6 1.4 1 0 0 1 1 1 1 WWE domain zf-RING_2 PF13639.1 EMC85946.1 - 2.8e-06 27.0 11.8 5.7e-06 26.0 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC85946.1 - 6.3e-06 25.7 10.2 1.1e-05 24.9 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC85946.1 - 1.5e-05 24.5 9.4 3.6e-05 23.3 6.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC85946.1 - 5.3e-05 23.1 13.2 9.4e-05 22.3 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC85946.1 - 0.0067 16.1 11.4 0.012 15.2 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC85946.1 - 0.013 15.3 10.7 0.013 15.3 7.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING MgsA_C PF12002.3 EMC85946.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal zf-RING_UBOX PF13445.1 EMC85946.1 - 0.077 12.7 9.0 0.17 11.6 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EMC85946.1 - 1 9.2 7.0 2.1 8.2 4.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Fer4_3 PF12798.2 EMC85947.1 - 7.2e-05 23.0 2.4 0.55 10.9 0.1 4.8 2 2 0 2 2 2 2 4Fe-4S binding domain DDHD PF02862.12 EMC85947.1 - 2.8 7.6 6.3 3.4 7.4 4.3 1.2 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 EMC85947.1 - 7.2 5.9 14.8 9.8 5.4 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) UPF0020 PF01170.13 EMC85948.1 - 1e-13 51.2 0.0 3e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMC85948.1 - 2.3e-07 30.8 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EMC85948.1 - 1.6e-05 24.1 0.0 2.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 EMC85948.1 - 0.0046 16.4 0.5 0.42 10.0 0.0 2.4 2 1 0 2 2 2 2 DNA methylase Methyltransf_15 PF09445.5 EMC85948.1 - 0.076 12.5 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Eco57I PF07669.6 EMC85948.1 - 0.088 13.1 0.1 0.38 11.1 0.0 2.1 3 0 0 3 3 3 0 Eco57I restriction-modification methylase Costars PF14705.1 EMC85949.1 - 5.8e-33 112.7 0.1 7.1e-33 112.4 0.1 1.1 1 0 0 1 1 1 1 Costars DcpS_C PF11969.3 EMC85950.1 - 5.5e-06 26.5 0.2 7.2e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding LysM PF01476.15 EMC85951.1 - 2.8e-06 27.0 0.1 6.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 LysM domain GRAM PF02893.15 EMC85951.1 - 0.0016 17.9 0.0 0.0043 16.5 0.0 1.7 1 0 0 1 1 1 1 GRAM domain HLH PF00010.21 EMC85952.1 - 6.3e-18 64.2 2.7 1.1e-17 63.4 1.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC85952.1 - 5.2e-14 51.7 0.1 9.2e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Hairy Orange DUF3772 PF12607.3 EMC85952.1 - 1 9.0 6.2 0.75 9.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) HD_3 PF13023.1 EMC85953.1 - 6.8e-46 156.0 0.3 8.5e-46 155.7 0.2 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EMC85953.1 - 0.00018 21.4 0.1 0.00036 20.5 0.1 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 EMC85953.1 - 0.0091 15.2 0.1 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Kinesin-relat_1 PF12711.2 EMC85953.1 - 0.083 13.2 2.1 0.17 12.3 1.4 1.6 1 0 0 1 1 1 0 Kinesin motor TPD52 PF04201.10 EMC85954.1 - 4.8e-77 257.2 8.9 6.5e-77 256.7 6.2 1.2 1 0 0 1 1 1 1 Tumour protein D52 family Vfa1 PF08432.5 EMC85954.1 - 0.0037 17.3 0.8 0.0055 16.7 0.6 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 ERM PF00769.14 EMC85954.1 - 0.0042 16.6 2.1 0.0051 16.3 1.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family IncA PF04156.9 EMC85954.1 - 0.0073 15.9 3.6 0.011 15.3 2.5 1.3 1 0 0 1 1 1 1 IncA protein TBPIP PF07106.8 EMC85954.1 - 0.0096 15.4 3.0 0.017 14.6 2.1 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EMC85954.1 - 0.013 14.1 2.9 0.016 13.9 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Siah-Interact_N PF09032.6 EMC85954.1 - 0.05 13.6 3.3 0.061 13.3 1.4 1.8 1 1 0 1 1 1 0 Siah interacting protein, N terminal DUF4140 PF13600.1 EMC85954.1 - 0.083 13.3 2.5 0.14 12.6 0.9 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) M_domain PF12938.2 EMC85954.1 - 0.11 12.2 2.0 0.11 12.2 0.2 1.8 1 1 1 2 2 2 0 M domain of GW182 Striatin PF08232.7 EMC85954.1 - 0.12 12.6 4.6 0.079 13.2 2.1 1.5 2 0 0 2 2 1 0 Striatin family PEP-utilisers_N PF05524.8 EMC85954.1 - 0.12 12.1 2.4 0.26 11.1 1.7 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF1192 PF06698.6 EMC85954.1 - 0.12 12.1 1.7 0.27 11.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) NUDE_C PF04880.8 EMC85954.1 - 0.13 12.5 6.7 0.29 11.4 4.6 1.9 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Rifin_STEVOR PF02009.11 EMC85954.1 - 0.14 11.7 3.3 0.077 12.6 1.1 1.4 2 0 0 2 2 2 0 Rifin/stevor family SlyX PF04102.7 EMC85954.1 - 0.16 12.3 3.5 0.42 11.0 2.4 1.8 1 1 0 1 1 1 0 SlyX Bacillus_HBL PF05791.6 EMC85954.1 - 0.26 10.6 5.4 0.71 9.2 3.0 2.1 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Takusan PF04822.8 EMC85954.1 - 0.28 10.9 4.6 0.74 9.6 3.2 1.8 1 1 0 1 1 1 0 Takusan Cep57_MT_bd PF06657.8 EMC85954.1 - 0.31 11.0 5.3 0.55 10.2 3.4 1.7 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 HsbA PF12296.3 EMC85954.1 - 0.46 10.3 5.4 0.6 9.9 0.4 2.7 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Herpes_BLRF2 PF05812.7 EMC85954.1 - 1.1 9.1 6.5 1.5 8.6 3.4 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Prefoldin_2 PF01920.15 EMC85954.1 - 2.7 7.8 11.3 1 9.1 5.0 2.3 2 1 0 2 2 2 0 Prefoldin subunit IBR PF01485.16 EMC85955.1 - 1.4e-17 63.3 26.6 7e-09 35.4 4.9 2.9 3 0 0 3 3 3 2 IBR domain C1_4 PF07975.7 EMC85955.1 - 3.9 7.5 25.6 0.27 11.2 1.2 4.3 3 1 0 3 3 3 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.7 EMC85955.1 - 4 7.2 26.5 0.064 13.0 4.8 3.8 3 1 1 4 4 4 0 zinc-ribbons NKAIN PF05640.9 EMC85956.1 - 1.1e-47 161.5 0.0 1.3e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Asp-B-Hydro_N PF05279.6 EMC85957.1 - 0.0018 18.2 42.0 0.044 13.6 29.1 2.3 1 1 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region IncA PF04156.9 EMC85957.1 - 0.016 14.7 0.2 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 IncA protein FGF-BP1 PF06473.7 EMC85957.1 - 0.19 11.2 15.1 0.31 10.6 10.5 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Pap_E4 PF02711.9 EMC85957.1 - 0.51 11.2 6.6 1.3 9.9 4.6 1.6 1 0 0 1 1 1 0 E4 protein DUF4551 PF15087.1 EMC85957.1 - 9.7 4.4 10.1 13 4.0 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CRAL_TRIO PF00650.15 EMC85958.1 - 9.2e-35 119.4 0.0 1.7e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EMC85958.1 - 8.4e-09 35.4 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC85958.1 - 3.1e-07 30.4 0.1 8.9e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Metallophos PF00149.23 EMC85959.1 - 8.5e-19 67.7 0.2 1.3e-18 67.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipocalin PF00061.18 EMC85960.1 - 4.4e-20 72.1 1.2 4.8e-20 72.0 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DBP10CT PF08147.7 EMC85960.1 - 0.092 12.5 0.5 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Myosin_N PF02736.14 EMC85960.1 - 0.82 9.3 3.2 0.66 9.6 0.4 2.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Serinc PF03348.10 EMC85961.1 - 5.6e-181 601.9 12.8 6.4e-181 601.7 8.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Vert_HS_TF PF06546.6 EMC85962.1 - 5.9e-79 265.1 29.9 1.8e-72 243.9 13.7 2.2 1 1 1 2 2 2 2 Vertebrate heat shock transcription factor HSF_DNA-bind PF00447.12 EMC85962.1 - 4e-27 94.4 0.4 9e-27 93.2 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding bZIP_2 PF07716.10 EMC85962.1 - 0.022 14.5 1.8 0.061 13.1 1.2 1.8 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.13 EMC85962.1 - 0.026 14.2 0.8 0.068 12.9 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper APG6 PF04111.7 EMC85962.1 - 0.54 9.2 6.9 0.073 12.1 2.1 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Ribosomal_L29 PF00831.18 EMC85963.1 - 0.0026 17.4 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L29 protein DUF2891 PF11199.3 EMC85963.1 - 0.068 11.7 0.1 0.076 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Connexin PF00029.14 EMC85964.1 - 2.7e-50 168.9 0.1 6.5e-50 167.6 0.1 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC85964.1 - 1.3e-31 108.1 2.9 3.3e-31 106.9 2.0 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin43 PF03508.8 EMC85964.1 - 8.8e-12 44.0 15.8 1.8e-11 42.9 11.0 1.6 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) TMEM154 PF15102.1 EMC85964.1 - 0.037 13.7 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family BROMI PF14961.1 EMC85965.1 - 0 2168.3 24.5 0 2168.1 17.0 1.0 1 0 0 1 1 1 1 Broad-minded protein RabGAP-TBC PF00566.13 EMC85965.1 - 0.00032 20.2 2.3 0.0011 18.4 1.6 2.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UBN_AB PF14075.1 EMC85965.1 - 0.0043 16.7 5.1 0.97 9.0 0.0 3.4 3 0 0 3 3 3 2 Ubinuclein conserved middle domain BUD22 PF09073.5 EMC85965.1 - 0.23 10.5 1.1 0.36 9.8 0.7 1.2 1 0 0 1 1 1 0 BUD22 Glyco_hydro_47 PF01532.15 EMC85966.1 - 1e-152 508.9 0.0 1.2e-152 508.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 EMC85966.1 - 0.023 13.7 0.1 0.1 11.6 0.1 2.0 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 ASF1_hist_chap PF04729.8 EMC85968.1 - 5.3e-65 217.7 0.1 6.6e-65 217.4 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.8 EMC85968.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Fib_alpha PF08702.5 EMC85969.1 - 6.2 6.9 58.5 0.13 12.3 2.3 5.7 3 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Phospholamban PF04272.9 EMC85970.1 - 2.6e-36 122.8 9.6 2.8e-36 122.7 6.7 1.0 1 0 0 1 1 1 1 Phospholamban Sarcolipin PF05366.6 EMC85970.1 - 0.0057 16.0 5.7 0.011 15.1 3.9 1.6 1 1 0 1 1 1 1 Sarcolipin DUF1705 PF08019.7 EMC85970.1 - 0.024 14.1 0.4 0.024 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) DUF914 PF06027.7 EMC85971.1 - 6.2e-133 442.7 11.1 7.5e-133 442.5 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EMC85971.1 - 6.3e-13 48.8 23.3 3.3e-07 30.3 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EMC85971.1 - 0.00026 20.6 19.3 0.019 14.6 6.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Mg_trans_NIPA PF05653.9 EMC85971.1 - 0.0018 17.2 2.3 0.0018 17.2 1.6 2.0 1 1 1 3 3 3 1 Magnesium transporter NIPA UAA PF08449.6 EMC85971.1 - 0.0055 15.6 14.9 0.0086 15.0 10.3 1.2 1 0 0 1 1 1 1 UAA transporter family DUF809 PF05663.6 EMC85971.1 - 0.098 12.5 0.1 0.098 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) EmrE PF13536.1 EMC85971.1 - 1.5 9.0 24.5 0.029 14.5 4.6 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Prenyltransf PF01255.14 EMC85972.1 - 4.2e-08 32.5 0.0 4.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Methyltransf_12 PF08242.7 EMC85972.1 - 0.0044 17.4 0.1 0.0069 16.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF3369 PF11849.3 EMC85972.1 - 0.0066 16.4 0.1 0.0086 16.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3369) Methyltransf_11 PF08241.7 EMC85972.1 - 0.0083 16.5 0.2 0.014 15.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC85972.1 - 0.028 14.0 0.5 0.059 12.9 0.4 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMC85972.1 - 0.067 13.5 0.2 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.1 EMC85973.1 - 6.2e-53 176.4 50.8 4.3e-12 45.5 0.4 6.6 4 1 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 EMC85973.1 - 3.8e-41 138.0 49.8 6.2e-08 32.0 0.9 10.0 3 3 8 12 12 12 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC85973.1 - 3.2e-24 81.2 44.9 0.024 14.6 0.0 16.0 15 2 1 16 16 16 8 Leucine Rich Repeat LRR_7 PF13504.1 EMC85973.1 - 3.5e-14 50.4 52.4 0.29 11.5 0.1 15.9 17 0 0 17 17 17 6 Leucine rich repeat LRR_5 PF13306.1 EMC85973.1 - 8.8e-11 41.6 6.5 7.6e-07 28.8 0.6 4.4 3 2 0 4 4 4 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC85973.1 - 7.2e-08 31.7 49.2 1.3 9.3 0.2 14.5 12 3 2 14 14 14 4 Leucine Rich repeat LRR_9 PF14580.1 EMC85973.1 - 8.3e-05 22.2 21.0 0.24 10.9 0.6 5.0 1 1 1 5 5 5 3 Leucine-rich repeat FNIP PF05725.7 EMC85973.1 - 0.2 11.6 12.5 0.31 11.0 0.0 5.5 4 2 0 4 4 4 0 FNIP Repeat F5_F8_type_C PF00754.20 EMC85974.1 - 1.9e-26 92.3 3.9 1.9e-26 92.3 2.7 1.9 2 0 0 2 2 2 1 F5/8 type C domain CUB PF00431.15 EMC85974.1 - 8.4e-19 67.6 0.3 4e-18 65.4 0.0 2.3 3 0 0 3 3 3 1 CUB domain LCCL PF03815.14 EMC85974.1 - 1.4e-18 66.6 0.4 3.2e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 LCCL domain Pkinase_Tyr PF07714.12 EMC85975.1 - 1.4e-96 322.5 0.0 2.2e-96 321.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC85975.1 - 2.3e-44 151.4 0.0 3.9e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC85975.1 - 3.6e-41 139.1 37.4 6.3e-08 32.6 0.4 9.9 9 0 0 9 9 9 8 Fibronectin type III domain Vg_Tdu PF07545.9 EMC85976.1 - 1.8e-20 72.0 0.2 2.9e-20 71.4 0.2 1.3 1 0 0 1 1 1 1 Vestigial/Tondu family FAM181 PF15238.1 EMC85976.1 - 0.23 11.4 7.4 0.4 10.7 5.0 1.6 1 1 0 1 1 1 0 FAM181 RFX_DNA_binding PF02257.10 EMC85977.1 - 7.1e-31 106.1 0.2 2.1e-30 104.7 0.2 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain RAG2_PHD PF13341.1 EMC85977.1 - 0.043 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 RAG2 PHD domain Pox_D5 PF03288.11 EMC85977.1 - 0.069 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like 7tm_3 PF00003.17 EMC85978.1 - 1.6e-70 237.1 31.7 3.7e-70 235.9 22.0 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 EMC85978.1 - 7.1e-59 199.3 0.4 1.2e-58 198.6 0.3 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.9 EMC85978.1 - 1e-14 53.9 15.6 2.6e-14 52.6 10.8 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 EMC85978.1 - 5.9e-07 29.1 0.0 1.4e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein CoA_binding_2 PF13380.1 EMC85978.1 - 0.069 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain DUF1075 PF06388.6 EMC85979.1 - 8.3e-48 161.7 2.4 9.2e-48 161.6 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) DUF1143 PF06608.6 EMC85979.1 - 0.11 12.4 0.1 0.29 11.1 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1143) Arm PF00514.18 EMC85980.1 - 5.2e-89 289.3 14.4 1.1e-12 47.2 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC85980.1 - 4.4e-30 103.7 0.0 2.8e-08 33.9 0.0 5.4 3 1 2 5 5 5 4 HEAT repeats IBB PF01749.15 EMC85980.1 - 2.7e-28 97.9 1.7 6.2e-28 96.8 1.2 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EMC85980.1 - 7.7e-25 86.7 2.5 3.1e-07 30.6 0.0 6.0 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.17 EMC85980.1 - 2.7e-18 64.3 10.5 6.7e-05 22.6 0.0 8.9 9 1 0 9 9 8 4 HEAT repeat RICTOR_V PF14668.1 EMC85980.1 - 2e-06 27.6 0.9 1.3 9.0 0.0 5.1 4 3 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 EMC85980.1 - 2.3e-06 26.9 0.0 0.025 13.6 0.0 2.8 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_C PF11698.3 EMC85980.1 - 5.9e-05 22.9 0.0 0.34 10.8 0.0 4.4 2 1 2 4 4 4 2 V-ATPase subunit H Adaptin_N PF01602.15 EMC85980.1 - 0.0002 19.8 0.0 0.0037 15.6 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 EMC85980.1 - 0.0036 15.6 0.1 0.65 8.1 0.0 2.8 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EMC85980.1 - 0.0058 16.9 2.3 5.4 7.7 0.0 5.0 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EMC85980.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 CLASP N terminal Peptidase_C78 PF07910.8 EMC85981.1 - 4.7e-73 244.9 0.0 6.9e-73 244.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.14 EMC85981.1 - 0.023 13.8 0.1 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C54 DUF2233 PF09992.4 EMC85981.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2233) Sulfotransfer_1 PF00685.22 EMC85982.1 - 5.4e-76 255.3 0.4 6.3e-76 255.1 0.3 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC85982.1 - 0.14 13.0 0.0 0.32 11.8 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase family RWD PF05773.17 EMC85983.1 - 3.3e-26 91.4 2.8 7.6e-26 90.2 1.9 1.6 1 0 0 1 1 1 1 RWD domain DUF445 PF04286.7 EMC85983.1 - 0.0062 16.1 7.0 0.0068 15.9 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF2135 PF09906.4 EMC85983.1 - 0.11 12.4 1.2 0.23 11.4 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) GOLD_2 PF13897.1 EMC85983.1 - 0.26 11.5 2.2 0.42 10.8 0.8 1.9 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Folliculin PF11704.3 EMC85983.1 - 0.48 9.9 4.1 0.84 9.2 2.8 1.5 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hydrolase_3 PF08282.7 EMC85983.1 - 1.3 8.5 6.5 3 7.3 4.2 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4484 PF14831.1 EMC85983.1 - 4.2 7.4 10.3 7.7 6.5 7.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Ca_hom_mod PF14798.1 EMC85984.1 - 3.5e-92 307.9 2.8 4.1e-92 307.6 2.0 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF2093 PF09866.4 EMC85984.1 - 0.29 10.3 3.5 20 4.4 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2093) TRAPP PF04051.11 EMC85985.1 - 5.3e-35 120.1 0.0 6.5e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ca_hom_mod PF14798.1 EMC85986.1 - 2.3e-89 298.6 11.9 2.8e-89 298.4 8.2 1.1 1 0 0 1 1 1 1 Calcium homeostasis modulator Clc-like PF07062.7 EMC85986.1 - 0.096 11.9 0.0 0.096 11.9 0.0 2.4 4 0 0 4 4 4 0 Clc-like ACOX PF01756.14 EMC85986.1 - 0.34 10.2 2.0 0.37 10.1 0.6 1.7 1 1 1 2 2 2 0 Acyl-CoA oxidase Ca_hom_mod PF14798.1 EMC85987.1 - 1.2e-80 270.1 7.5 1.4e-80 269.9 5.2 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DltD_M PF04918.7 EMC85988.1 - 0.03 14.5 3.2 0.078 13.1 2.2 1.6 1 0 0 1 1 1 0 DltD central region DUF1673 PF07895.6 EMC85988.1 - 0.43 10.0 7.2 2.1 7.8 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) 5_nucleotid PF05761.9 EMC85989.1 - 2.2e-56 191.3 0.2 2.9e-56 190.8 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 EMC85989.1 - 0.0036 17.5 0.6 0.067 13.3 0.0 2.9 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Collagen PF01391.13 EMC85990.1 - 2.3e-68 225.6 289.2 4.1e-09 35.8 22.8 10.2 1 1 7 8 8 8 6 Collagen triple helix repeat (20 copies) C1q PF00386.16 EMC85990.1 - 2.7e-39 134.0 0.1 3.4e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 C1q domain Pkinase_Tyr PF07714.12 EMC85991.1 - 1.7e-96 322.3 0.0 2.1e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC85991.1 - 2.5e-48 164.4 0.0 3.3e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC85991.1 - 9.9e-26 89.3 0.0 2.7e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.23 EMC85991.1 - 6e-13 47.9 0.0 1.3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC85991.1 - 3.2e-10 39.4 0.1 8.9e-10 38.0 0.1 1.8 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC85991.1 - 6.9e-08 31.8 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 EMC85991.1 - 9.4e-05 22.2 0.0 0.28 10.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC85991.1 - 0.009 15.0 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like B2 PF11473.3 EMC85991.1 - 0.048 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 DUF1899 PF08953.6 EMC85992.1 - 0.00025 20.6 1.1 7.2 6.3 0.0 5.4 1 1 3 4 4 4 2 Domain of unknown function (DUF1899) VQ PF05678.9 EMC85992.1 - 0.0034 16.4 9.1 22 4.1 0.0 6.6 5 2 3 9 9 9 2 VQ motif Hemopexin PF00045.14 EMC85992.1 - 0.014 15.1 11.2 5.8 6.7 0.2 5.2 2 1 3 5 5 5 0 Hemopexin Qn_am_d_aIII PF09099.5 EMC85992.1 - 0.11 12.8 1.8 39 4.6 0.0 4.7 1 1 3 6 6 6 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III MinE PF03776.9 EMC85992.1 - 2.4 7.7 21.9 17 4.9 0.6 6.5 2 1 3 5 5 5 0 Septum formation topological specificity factor MinE AAA_9 PF12781.2 EMC85992.1 - 7.1 5.4 16.0 5.2 5.8 1.1 3.2 1 1 2 3 3 3 0 ATP-binding dynein motor region D5 SNF2_N PF00176.18 EMC85993.1 - 2.4e-22 79.1 0.1 2.5e-22 79.0 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EMC85993.1 - 0.0027 17.8 0.1 0.0035 17.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EMC85993.1 - 0.0042 16.9 0.0 0.0047 16.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC85993.1 - 0.0044 16.5 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EMC85993.1 - 0.035 13.0 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ino80_Iec3 PF14612.1 EMC85993.1 - 0.14 12.2 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling bZIP_1 PF00170.16 EMC85996.1 - 1.5e-14 53.6 16.2 5.9e-14 51.7 11.0 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EMC85996.1 - 3.2e-10 39.6 10.5 3.2e-10 39.6 7.2 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC85996.1 - 1.2e-06 28.7 10.7 2.5e-06 27.7 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 EMC85996.1 - 0.0024 18.1 2.0 0.0078 16.4 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF904) FlaC_arch PF05377.6 EMC85996.1 - 0.0083 16.0 1.2 0.021 14.6 0.9 1.7 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EMC85996.1 - 0.027 14.6 8.0 0.05 13.7 5.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.6 EMC85996.1 - 0.067 10.7 2.6 0.095 10.2 1.8 1.1 1 0 0 1 1 1 0 Prominin APG6 PF04111.7 EMC85996.1 - 0.074 12.0 7.4 0.12 11.3 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TBCA PF02970.11 EMC85996.1 - 0.14 12.2 8.9 0.31 11.1 6.2 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A ADIP PF11559.3 EMC85996.1 - 0.17 11.8 10.8 0.33 10.8 7.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Herpes_BLRF2 PF05812.7 EMC85996.1 - 0.4 10.4 10.0 0.9 9.3 2.8 2.5 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF1664 PF07889.7 EMC85996.1 - 0.59 9.9 4.4 0.97 9.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 EMC85996.1 - 0.7 10.3 4.3 2.5 8.5 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) V_ATPase_I PF01496.14 EMC85996.1 - 1.5 6.6 5.1 2.1 6.0 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 EMC85996.1 - 9 6.1 8.9 9.4 6.1 2.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S7 PF00177.16 EMC85997.1 - 1.6e-22 79.7 0.5 1.9e-12 47.0 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S7p/S5e 7tm_3 PF00003.17 EMC85999.1 - 2e-42 145.1 3.3 2.9e-42 144.6 2.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 EMC85999.1 - 4.2e-28 98.1 0.0 1.3e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region TctB PF07331.6 EMC85999.1 - 0.011 15.4 0.4 0.011 15.4 0.3 3.2 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF2975 PF11188.3 EMC85999.1 - 0.024 14.3 4.7 0.19 11.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Inhibitor_I71 PF12628.2 EMC85999.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Glyco_hydro_31 PF01055.21 EMC86000.1 - 5.4e-29 101.3 0.0 5.9e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ubiquitin PF00240.18 EMC86002.1 - 1.4e-18 66.0 0.0 2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC86002.1 - 9.5e-08 31.6 0.0 1.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EMC86002.1 - 0.00032 20.5 0.0 0.00067 19.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ParcG PF10274.4 EMC86003.1 - 3.1e-74 248.8 0.3 8.3e-55 185.5 0.0 2.0 1 1 1 2 2 2 2 Parkin co-regulated protein KH_1 PF00013.24 EMC86004.1 - 3.7e-06 26.4 0.4 1.8e-05 24.3 0.3 2.0 1 1 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC86004.1 - 0.00011 21.7 0.1 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 KH domain PDEase_I PF00233.14 EMC86006.1 - 3.4e-66 223.4 0.1 6.8e-66 222.4 0.1 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 EMC86006.1 - 2e-35 122.2 0.0 3.5e-25 88.9 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EMC86006.1 - 2.1e-21 76.3 0.0 3.4e-13 49.8 0.0 2.7 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 EMC86006.1 - 1.2e-14 55.0 0.0 2e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 GAF domain HD PF01966.17 EMC86006.1 - 0.053 13.5 0.2 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 HD domain Got1 PF04178.7 EMC86007.1 - 1.4e-32 112.2 14.0 1.4e-32 112.2 9.7 1.4 1 1 1 2 2 2 2 Got1/Sft2-like family DUF4293 PF14126.1 EMC86007.1 - 0.53 10.2 8.1 0.2 11.5 3.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF4064 PF13273.1 EMC86007.1 - 1.1 9.4 9.3 12 6.1 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) PGG PF13962.1 EMC86007.1 - 2.1 7.9 8.6 0.92 9.1 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function FtsX PF02687.16 EMC86007.1 - 4.8 6.9 11.8 1 9.1 4.8 2.2 1 1 1 2 2 2 0 FtsX-like permease family MPC PF03650.8 EMC86009.1 - 1.5e-34 118.5 0.2 1.8e-34 118.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Ribonuclease_T2 PF00445.13 EMC86010.1 - 9.4e-44 149.2 8.7 1.2e-43 148.9 6.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family FOP_dimer PF09398.5 EMC86011.1 - 1.2e-33 114.9 3.5 1.2e-33 114.8 0.0 2.7 4 0 0 4 4 4 1 FOP N terminal dimerisation domain 7tm_1 PF00001.16 EMC86012.1 - 7.8e-53 179.2 21.6 9.8e-53 178.9 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86012.1 - 0.00022 20.4 27.7 0.00031 19.9 19.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TRF PF08558.5 EMC86012.1 - 0.0029 16.9 1.5 0.0043 16.4 1.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Tcp10_C PF07202.8 EMC86014.1 - 4.2e-90 300.0 7.8 4.7e-90 299.9 5.4 1.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DUF4520 PF15016.1 EMC86014.1 - 0.0039 16.7 0.3 1.4 8.5 0.0 3.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4520) Rib PF08428.5 EMC86014.1 - 0.0044 16.7 3.5 20 5.0 0.1 4.3 4 1 1 5 5 5 1 Rib/alpha-like repeat DUF4176 PF13780.1 EMC86014.1 - 0.037 13.7 0.1 0.41 10.4 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4176) DUF402 PF04167.8 EMC86014.1 - 0.041 13.7 0.2 3.4 7.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF402) DUF2874 PF11396.3 EMC86014.1 - 0.071 13.0 1.8 7 6.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) TTL PF03133.10 EMC86015.1 - 4.2e-78 262.2 0.1 6.2e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMC86015.1 - 0.00054 18.8 0.1 0.0024 16.7 0.0 2.0 2 1 1 3 3 3 1 YheC/D like ATP-grasp UNC-93 PF05978.11 EMC86016.1 - 3.3e-12 46.1 8.8 3.3e-12 46.1 6.1 3.4 2 1 1 3 3 3 2 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EMC86016.1 - 6.8e-05 21.7 34.5 0.0032 16.2 5.6 2.9 1 1 1 3 3 3 3 Major Facilitator Superfamily RA PF00788.18 EMC86017.1 - 2.1e-46 156.3 0.0 1.2e-23 83.3 0.0 3.0 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.14 EMC86017.1 - 2.5e-29 101.2 0.5 7e-29 99.7 0.4 1.8 1 0 0 1 1 1 1 DIL domain PDZ PF00595.19 EMC86017.1 - 4.4e-17 62.0 0.5 1e-16 60.8 0.4 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FHA PF00498.21 EMC86017.1 - 2.5e-07 30.7 0.0 6.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain PDZ_2 PF13180.1 EMC86017.1 - 9e-05 22.2 0.4 0.00024 20.9 0.3 1.7 1 0 0 1 1 1 1 PDZ domain DUF4477 PF14780.1 EMC86017.1 - 0.011 15.0 0.6 0.027 13.8 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4477) FERM_M PF00373.13 EMC86018.1 - 8.8e-20 71.1 0.5 2.3e-19 69.8 0.4 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 EMC86018.1 - 2.8e-17 62.5 0.5 6.5e-17 61.3 0.3 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.5 EMC86018.1 - 4.7e-17 61.9 0.0 1.1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Dapper PF15268.1 EMC86019.1 - 2.1e-213 711.3 35.3 2.5e-213 711.0 24.5 1.1 1 0 0 1 1 1 1 Dapper Sulfotransfer_1 PF00685.22 EMC86020.1 - 3.8e-66 223.0 0.4 4.5e-66 222.8 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC86020.1 - 0.00062 20.7 0.0 0.0023 18.9 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 EMC86020.1 - 0.0095 15.4 0.1 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 Stf0 sulphotransferase Vasculin PF15337.1 EMC86020.1 - 0.023 15.1 4.4 0.67 10.4 0.1 3.1 3 0 0 3 3 3 0 Vascular protein family Vasculin-like 1 AAA_18 PF13238.1 EMC86020.1 - 0.098 12.9 0.2 1.8 8.8 0.0 2.5 2 1 1 3 3 3 0 AAA domain Thyroglobulin_1 PF00086.13 EMC86021.1 - 4.9e-30 102.6 27.8 4.1e-16 58.0 3.1 3.1 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 EMC86021.1 - 9.5e-15 54.6 0.7 2e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.10 EMC86021.1 - 2.4e-07 30.5 1.9 2.4e-07 30.5 1.3 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 EMC86021.1 - 3.1e-05 24.0 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC86021.1 - 3.3e-05 22.8 0.2 0.82 9.1 0.0 3.5 3 0 0 3 3 3 2 EF hand Kazal_1 PF00050.16 EMC86021.1 - 0.00026 20.9 3.9 0.00026 20.9 2.7 2.6 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.1 EMC86021.1 - 0.00033 20.3 0.2 1 9.4 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EMC86021.1 - 0.0093 15.2 0.0 0.26 10.6 0.0 3.2 3 0 0 3 3 3 1 EF hand TSP_C PF05735.7 EMC86022.1 - 7.9e-96 319.4 2.4 1.2e-95 318.7 1.6 1.3 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 EMC86022.1 - 7.3e-58 191.7 138.0 6.6e-12 44.6 10.7 10.4 8 2 2 10 10 10 8 Thrombospondin type 3 repeat TSP_1 PF00090.14 EMC86022.1 - 8.8e-43 144.2 60.6 3.1e-16 59.2 6.3 5.2 5 0 0 5 5 5 3 Thrombospondin type 1 domain VWC PF00093.13 EMC86022.1 - 5e-13 48.9 17.2 5e-13 48.9 11.9 6.1 5 1 0 5 5 5 1 von Willebrand factor type C domain EGF_3 PF12947.2 EMC86022.1 - 2.1e-07 30.7 7.1 2.1e-07 30.7 4.9 6.0 6 0 0 6 6 6 2 EGF domain EGF_CA PF07645.10 EMC86022.1 - 4.2e-06 26.6 1.7 4.2e-06 26.6 1.2 5.3 4 0 0 4 4 4 2 Calcium-binding EGF domain EGF PF00008.22 EMC86022.1 - 0.00094 19.0 5.6 0.00094 19.0 3.9 4.6 3 0 0 3 3 3 1 EGF-like domain WD40 PF00400.27 EMC86023.1 - 1.9e-24 84.5 9.3 1.7e-10 40.3 0.8 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EMC86023.1 - 0.014 13.5 0.3 0.086 10.9 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PHD PF00628.24 EMC86025.1 - 8.1e-17 60.6 25.2 4.7e-09 35.7 7.4 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.1 EMC86025.1 - 0.00026 20.2 4.5 0.00026 20.2 3.1 2.7 2 1 0 2 2 2 1 PHD-finger Requiem_N PF14051.1 EMC86025.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. zf-PHD-like PF15446.1 EMC86025.1 - 0.065 12.5 17.2 0.039 13.2 1.9 3.0 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain Tctex-1 PF03645.8 EMC86026.1 - 7.5e-24 83.5 0.3 9.1e-24 83.2 0.2 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF4209 PF13910.1 EMC86027.1 - 2.6e-26 91.5 0.1 6e-23 80.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Proteasome PF00227.21 EMC86029.1 - 5e-39 133.5 0.1 6.4e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_C1 PF02167.10 EMC86029.1 - 0.052 13.2 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C1 family DUF2997 PF11211.3 EMC86029.1 - 0.13 11.6 0.8 0.68 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) TBP PF00352.16 EMC86030.1 - 2.7e-64 212.5 0.3 6e-32 108.8 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMC86030.1 - 0.00065 19.6 3.4 0.89 9.6 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 EMC86030.1 - 0.038 14.3 0.5 0.1 12.9 0.0 1.8 1 1 1 2 2 2 0 Ribonuclease (pollen allergen) Auxin_repressed PF05564.7 EMC86030.1 - 0.94 10.0 4.2 2.2 8.8 2.9 1.7 1 1 0 1 1 1 0 Dormancy/auxin associated protein PDCD2_C PF04194.8 EMC86031.1 - 2.8e-41 140.8 0.2 3.6e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Acyltransferase PF01553.16 EMC86032.1 - 9.8e-24 83.2 0.0 1.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF4602 PF15375.1 EMC86033.1 - 7.9e-23 81.0 15.7 8.6e-23 80.8 10.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) Med19 PF10278.4 EMC86033.1 - 2.3 7.8 16.6 2.8 7.5 11.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SPRY PF00622.23 EMC86034.1 - 2e-15 56.9 0.0 3.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.16 EMC86034.1 - 1.5e-08 34.6 0.0 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain zf-B_box PF00643.19 EMC86034.1 - 3.3e-07 30.0 3.6 9e-07 28.6 2.5 1.8 1 0 0 1 1 1 1 B-box zinc finger PRY PF13765.1 EMC86034.1 - 1.7e-05 24.2 0.1 4.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 SPRY-associated domain Laminin_G_3 PF13385.1 EMC86034.1 - 0.0005 20.3 1.3 0.0012 19.1 0.9 1.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Barstar PF01337.13 EMC86034.1 - 0.0089 15.8 0.7 0.19 11.5 0.0 2.2 1 1 1 2 2 2 1 Barstar (barnase inhibitor) zf-UBR PF02207.15 EMC86034.1 - 0.036 13.7 2.6 0.12 12.1 1.8 1.9 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) YlbD_coat PF14071.1 EMC86034.1 - 0.049 13.6 1.9 7.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Putative coat protein IBR PF01485.16 EMC86034.1 - 0.98 9.3 6.2 1.1 9.1 1.6 2.6 2 0 0 2 2 2 0 IBR domain Arv1 PF04161.8 EMC86035.1 - 2e-35 122.6 4.1 2.4e-35 122.3 2.9 1.1 1 0 0 1 1 1 1 Arv1-like family TPR_11 PF13414.1 EMC86036.1 - 6.2e-40 134.6 9.2 9.4e-09 34.8 0.2 5.6 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 EMC86036.1 - 2.6e-29 99.5 21.1 2.9e-08 32.9 0.5 9.1 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMC86036.1 - 3e-29 98.5 12.4 7e-06 25.5 0.4 8.9 8 2 1 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86036.1 - 2.5e-26 91.7 0.1 5.9e-09 36.3 0.0 4.9 5 1 1 6 6 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC86036.1 - 4.4e-18 63.6 11.4 8.1e-06 25.2 0.2 8.1 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86036.1 - 2.6e-17 62.5 10.7 4.6e-08 32.8 0.9 5.0 1 1 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86036.1 - 2.9e-16 59.5 6.1 1.1e-05 25.6 1.1 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86036.1 - 1.2e-15 56.2 3.3 0.31 11.3 0.1 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMC86036.1 - 3e-15 55.8 1.0 0.00047 19.9 0.0 5.2 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC86036.1 - 4.1e-13 48.6 4.7 0.016 15.7 0.1 7.5 2 1 6 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC86036.1 - 2.6e-08 33.8 8.3 0.039 14.0 0.8 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC86036.1 - 3.3e-05 24.0 4.6 2.4 8.8 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC86036.1 - 4.2e-05 23.0 4.4 0.01 15.5 0.1 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 EMC86036.1 - 0.00022 20.1 0.6 0.3 9.7 0.3 2.5 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.4 EMC86036.1 - 0.00025 20.2 9.8 0.64 9.3 0.1 4.8 5 0 0 5 5 5 2 SHNi-TPR TPR_10 PF13374.1 EMC86036.1 - 0.0045 16.8 1.0 0.15 11.9 0.2 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC86036.1 - 0.011 15.5 2.0 8.3 6.3 0.1 3.6 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EMC86036.1 - 0.015 15.5 0.4 2.4 8.4 0.0 2.8 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Rapsyn_N PF10579.4 EMC86036.1 - 0.091 12.5 0.9 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Peptidase_C2 PF00648.16 EMC86038.1 - 6.7e-139 461.9 0.1 3.2e-138 459.7 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 EMC86038.1 - 2.2e-58 196.0 0.0 3.8e-58 195.3 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.1 EMC86038.1 - 8.8e-10 37.6 1.6 0.0014 18.2 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 EMC86038.1 - 9.3e-10 37.0 3.0 0.00056 19.0 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EMC86038.1 - 1e-07 32.0 1.4 0.015 15.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC86038.1 - 1.8e-06 27.4 0.3 0.00063 19.3 0.0 3.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC86038.1 - 0.0041 16.4 0.2 3.3 7.2 0.0 3.2 2 0 0 2 2 2 2 EF hand Ndufs5 PF10200.4 EMC86038.1 - 0.051 13.5 0.2 0.66 10.0 0.0 2.7 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Serpin PF00079.15 EMC86039.1 - 6.3e-60 203.2 0.0 7.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DDE_Tnp_1_7 PF13843.1 EMC86040.1 - 9.5e-81 271.5 0.5 1.1e-80 271.3 0.3 1.0 1 0 0 1 1 1 1 Transposase IS4 HEPN PF05168.9 EMC86040.1 - 0.068 13.0 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 HEPN domain WD40 PF00400.27 EMC86041.1 - 9.1e-64 209.2 8.6 9.2e-13 47.5 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EMC86041.1 - 9e-40 136.0 3.0 1.4e-39 135.4 2.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EMC86041.1 - 3.3e-06 25.5 0.7 0.0012 17.0 0.2 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 CAGE1 PF15066.1 EMC86041.1 - 0.078 11.4 0.8 0.23 9.8 0.0 1.8 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family ABC_membrane PF00664.18 EMC86042.1 - 3.1e-54 184.2 6.0 4.4e-54 183.7 4.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMC86042.1 - 1.1e-33 116.4 0.0 2.5e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMC86042.1 - 1.7e-07 30.6 0.0 5.8e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC86042.1 - 5.1e-07 29.9 0.1 6.5e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EMC86042.1 - 5.2e-05 22.0 0.1 0.0033 16.0 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMC86042.1 - 0.0006 19.8 0.9 0.0039 17.1 0.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EMC86042.1 - 0.00068 19.8 0.2 0.011 15.9 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC86042.1 - 0.0009 19.3 0.2 0.0093 16.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMC86042.1 - 0.0017 17.8 0.1 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMC86042.1 - 0.002 17.5 0.9 0.014 14.7 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC86042.1 - 0.0028 17.3 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 1 1 Part of AAA domain DUF258 PF03193.11 EMC86042.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC86042.1 - 0.0069 17.2 0.1 0.015 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC86042.1 - 0.01 15.5 0.2 0.069 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMC86042.1 - 0.027 14.3 0.0 0.24 11.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 EMC86042.1 - 0.066 12.7 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMC86042.1 - 0.078 12.9 0.2 0.27 11.1 0.1 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EMC86042.1 - 0.082 12.7 0.0 0.39 10.5 0.0 2.2 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 EMC86042.1 - 0.095 12.4 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EMC86042.1 - 0.17 12.2 0.0 0.53 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain PPV_E1_C PF00519.12 EMC86042.1 - 0.23 10.0 0.0 0.51 8.9 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase Nucleoporin_C PF03177.9 EMC86043.1 - 5.1e-90 302.6 18.1 6.8e-90 302.2 12.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMC86043.1 - 1.3e-28 99.9 0.7 2e-28 99.3 0.5 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Actin PF00022.14 EMC86044.1 - 1.3e-134 448.4 0.0 1.5e-134 448.3 0.0 1.0 1 0 0 1 1 1 1 Actin DUF3377 PF11857.3 EMC86045.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Miff PF05644.6 EMC86046.1 - 1.4 8.4 10.6 1.7 8.1 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Ras PF00071.17 EMC86047.1 - 3.5e-59 198.8 0.2 4e-59 198.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC86047.1 - 1.7e-21 76.9 0.0 2.6e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC86047.1 - 4.7e-14 52.0 0.0 6.3e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC86047.1 - 1.4e-06 27.9 0.0 2.4e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC86047.1 - 2.5e-05 24.2 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC86047.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMC86047.1 - 0.0027 16.9 0.0 0.0043 16.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMC86047.1 - 0.0062 16.6 0.1 0.024 14.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EMC86047.1 - 0.0066 15.9 0.1 0.023 14.2 0.0 1.8 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EMC86047.1 - 0.01 15.8 0.1 0.017 15.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 EMC86047.1 - 0.022 14.3 0.0 2.8 7.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 EMC86047.1 - 0.053 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Septin KaiC PF06745.8 EMC86047.1 - 0.064 12.3 0.4 0.11 11.5 0.1 1.5 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 EMC86047.1 - 0.085 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EMC86047.1 - 0.096 12.3 0.1 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EMC86047.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain BBS2_N PF14781.1 EMC86047.1 - 0.11 12.1 0.2 2.3 7.8 0.0 2.5 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal T2SE PF00437.15 EMC86047.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 EMC86047.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EMC86047.1 - 0.14 12.3 0.1 0.98 9.6 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.17 EMC86048.1 - 6.4e-35 119.9 0.0 8.1e-35 119.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC86048.1 - 1.5e-09 38.3 0.0 3.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Lipase_GDSL_3 PF14606.1 EMC86048.1 - 0.0046 16.7 0.0 0.0061 16.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GTP_EFTU PF00009.22 EMC86048.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SprT-like PF10263.4 EMC86049.1 - 5.7e-36 123.5 1.4 5.7e-36 123.5 1.0 1.8 2 0 0 2 2 2 1 SprT-like family Rad50_zn_hook PF04423.9 EMC86049.1 - 0.05 13.0 1.1 4 6.9 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif WLM PF08325.5 EMC86049.1 - 1.7 8.5 7.5 6.8 6.5 5.2 2.2 1 1 0 1 1 1 0 WLM domain Translin PF01997.11 EMC86050.1 - 1.6e-60 204.1 0.2 1.9e-60 203.9 0.1 1.1 1 0 0 1 1 1 1 Translin family GRIM-19 PF06212.7 EMC86050.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 GRIM-19 protein Laminin_II PF06009.7 EMC86051.1 - 0.0023 17.7 0.5 0.0023 17.7 0.3 4.5 4 1 1 5 5 5 1 Laminin Domain II DUF72 PF01904.13 EMC86051.1 - 0.0072 16.1 7.0 0.097 12.4 2.6 2.5 2 0 0 2 2 2 1 Protein of unknown function DUF72 UVR PF02151.14 EMC86051.1 - 0.013 15.0 7.6 0.013 15.0 5.3 3.1 2 0 0 2 2 2 0 UvrB/uvrC motif TMF_DNA_bd PF12329.3 EMC86051.1 - 0.2 11.4 0.1 0.2 11.4 0.1 6.0 5 2 2 7 7 7 0 TATA element modulatory factor 1 DNA binding CHD5 PF04420.9 EMC86051.1 - 0.3 10.7 17.6 0.06 12.9 0.3 4.0 3 1 1 4 4 4 0 CHD5-like protein Baculo_PEP_C PF04513.7 EMC86051.1 - 0.4 10.5 10.8 2.3 8.0 0.1 4.4 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.9 EMC86051.1 - 3.6 7.5 30.4 0.5 10.3 0.2 4.5 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) Reo_sigmaC PF04582.7 EMC86051.1 - 4.4 6.3 8.1 1.3 8.0 2.2 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF3401 PF11881.3 EMC86052.1 - 2.5e-77 259.4 0.3 5.4e-77 258.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3401) Rap_GAP PF02145.10 EMC86052.1 - 2.2e-62 209.7 0.0 5.7e-62 208.4 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 EMC86052.1 - 1.6e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) IncA PF04156.9 EMC86052.1 - 0.0042 16.7 2.5 0.0095 15.5 1.7 1.5 1 0 0 1 1 1 1 IncA protein DUF2968 PF11180.3 EMC86052.1 - 5.2 6.4 11.8 0.3 10.4 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) HPHLAWLY PF14925.1 EMC86053.1 - 2.8e-63 213.9 31.5 4e-62 210.1 21.9 2.4 1 1 0 1 1 1 1 Domain of unknown function NTPase_1 PF03266.10 EMC86054.1 - 3.1e-60 202.6 0.5 3.5e-60 202.5 0.4 1.0 1 0 0 1 1 1 1 NTPase DUF2478 PF10649.4 EMC86054.1 - 0.0081 15.4 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2478) ACT PF01842.20 EMC86054.1 - 0.014 14.9 0.2 0.1 12.0 0.0 2.4 2 1 1 3 3 3 0 ACT domain MobB PF03205.9 EMC86054.1 - 0.028 14.1 0.3 0.066 12.9 0.1 1.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EMC86054.1 - 0.044 13.6 0.0 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMC86054.1 - 0.063 12.8 0.2 0.24 10.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMC86054.1 - 0.083 13.0 0.1 0.31 11.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC86054.1 - 0.13 12.4 0.1 0.75 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain Pecanex_C PF05041.10 EMC86055.1 - 1.8e-121 403.4 0.0 3.3e-121 402.6 0.0 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Pkinase_Tyr PF07714.12 EMC86056.1 - 4.5e-31 107.8 0.0 8.5e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC86056.1 - 6.3e-25 87.7 0.0 2.6e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain DUF3552 PF12072.3 EMC86056.1 - 0.043 13.0 13.3 0.078 12.1 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.9 EMC86056.1 - 4.5 7.1 10.1 9.8 6.0 7.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EamA PF00892.15 EMC86057.1 - 2.6e-07 30.7 2.6 2.6e-07 30.7 1.8 3.8 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EMC86057.1 - 5.7e-07 29.7 3.3 5.7e-07 29.7 2.3 4.0 2 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 EMC86057.1 - 1.2e-06 28.2 0.6 1.2e-06 28.2 0.4 2.8 3 1 0 3 3 3 1 Triose-phosphate Transporter family DUF914 PF06027.7 EMC86057.1 - 5.8e-06 25.3 22.1 8.9e-06 24.7 15.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) COX6B PF02297.12 EMC86058.1 - 1.6e-09 37.6 3.8 3.4e-09 36.6 2.6 1.5 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CG-1 PF03859.11 EMC86058.1 - 0.0041 16.6 0.3 0.0048 16.4 0.2 1.0 1 0 0 1 1 1 1 CG-1 domain SpoU_methylase PF00588.14 EMC86059.1 - 2.2e-30 105.3 0.0 6.2e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family MAS20 PF02064.10 EMC86060.1 - 2e-32 111.6 0.1 2.3e-32 111.4 0.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor TPR_11 PF13414.1 EMC86060.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 TPR repeat DUF221 PF02714.10 EMC86060.1 - 0.021 13.7 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 TPR_14 PF13428.1 EMC86060.1 - 0.036 14.6 0.2 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC86060.1 - 0.044 13.3 0.1 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SicP-binding PF09119.5 EMC86060.1 - 0.059 13.0 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 SicP binding TPR_2 PF07719.12 EMC86060.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.17 EMC86061.1 - 1e-30 105.1 0.8 3.9e-16 58.4 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC86061.1 - 1.1e-22 79.7 0.4 1.3e-14 53.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC86061.1 - 3e-10 39.7 1.9 1e-05 25.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC86061.1 - 0.0003 20.4 0.0 0.059 13.1 0.0 2.7 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EMC86061.1 - 0.00098 18.8 0.1 0.72 9.6 0.0 2.3 1 1 1 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMC86061.1 - 0.036 13.9 0.3 10 6.0 0.0 3.1 2 2 0 3 3 3 0 RNA binding motif DUF1866 PF08952.6 EMC86061.1 - 0.068 12.7 0.0 3.1 7.3 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1866) Spo7_2_N PF15407.1 EMC86061.1 - 0.12 11.8 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein family 7 polyprenyl_synt PF00348.12 EMC86062.1 - 6.6e-49 166.1 0.0 8.7e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF948 PF06103.6 EMC86062.1 - 0.14 12.0 0.1 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Galactosyl_T PF01762.16 EMC86063.1 - 6.4e-28 97.6 0.0 3.3e-25 88.8 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.11 EMC86063.1 - 0.019 14.1 0.2 0.63 9.2 0.0 2.3 2 0 0 2 2 2 0 Fringe-like G-gamma PF00631.17 EMC86064.1 - 1.9e-17 62.7 0.0 2.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain Beach PF02138.13 EMC86065.1 - 9.2e-28 97.4 0.1 1.8e-27 96.5 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EMC86065.1 - 1.4e-24 85.9 0.0 3.2e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH G2F PF07474.7 EMC86066.1 - 4.2e-80 267.6 0.8 6.7e-80 267.0 0.5 1.3 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.12 EMC86066.1 - 6e-39 132.1 4.0 9.4e-12 45.0 0.0 4.9 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.2 EMC86066.1 - 3.7e-32 109.9 103.4 2.5e-09 36.9 7.0 6.6 6 0 0 6 6 6 6 EGF domain NIDO PF06119.9 EMC86066.1 - 1.2e-22 80.3 0.7 3.6e-22 78.8 0.5 1.9 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.10 EMC86066.1 - 1.6e-20 72.8 94.1 2.8e-09 36.7 6.5 6.9 6 0 0 6 6 5 5 Calcium-binding EGF domain cEGF PF12662.2 EMC86066.1 - 3.5e-18 64.9 51.7 9.3e-07 28.3 0.9 6.7 6 0 0 6 6 6 5 Complement Clr-like EGF-like Thyroglobulin_1 PF00086.13 EMC86066.1 - 2e-17 62.2 1.6 1.1e-16 59.9 1.1 2.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat FXa_inhibition PF14670.1 EMC86066.1 - 2.7e-15 56.2 94.5 2e-08 34.1 4.9 6.5 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 EMC86066.1 - 1.5e-09 37.6 96.8 0.00036 20.4 4.2 7.0 7 0 0 7 7 6 6 EGF-like domain SGL PF08450.7 EMC86066.1 - 2.2e-05 23.9 0.0 8.1e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region EGF_MSP1_1 PF12946.2 EMC86066.1 - 0.0017 18.0 66.2 0.0026 17.4 1.0 5.9 6 0 0 6 6 5 3 MSP1 EGF domain 1 hEGF PF12661.2 EMC86066.1 - 0.37 10.9 27.2 0.19 11.9 0.3 6.9 6 0 0 6 6 6 0 Human growth factor-like EGF PspB PF06667.7 EMC86067.1 - 0.022 14.6 3.2 0.062 13.2 2.2 1.8 1 0 0 1 1 1 0 Phage shock protein B Death PF00531.17 EMC86068.1 - 1.4e-11 43.9 0.1 2.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Death domain Gal-bind_lectin PF00337.17 EMC86069.1 - 1.8e-73 244.1 0.0 6.4e-38 129.1 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin WIF PF02019.13 EMC86069.1 - 0.02 14.3 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 WIF domain DUF1080 PF06439.6 EMC86069.1 - 0.12 12.2 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) Spectrin PF00435.16 EMC86070.1 - 1.3e-74 247.1 34.1 6.7e-25 87.4 5.9 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 EMC86070.1 - 3e-42 143.0 0.2 6.7e-23 80.8 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EMC86070.1 - 4.1e-27 93.9 0.0 2.4e-26 91.4 0.0 2.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EMC86070.1 - 5.2e-13 48.4 0.1 3.9e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.27 EMC86070.1 - 8.6e-09 34.0 0.9 0.0025 16.9 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMC86070.1 - 1.7e-07 30.7 0.5 7.5e-07 28.6 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EMC86070.1 - 3.3e-05 23.9 0.6 0.00012 22.1 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC86070.1 - 4.1e-05 23.1 2.9 0.033 14.0 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain XisI PF08869.6 EMC86070.1 - 0.23 11.5 5.4 0.096 12.8 0.5 2.6 2 0 0 2 2 2 0 XisI protein S-methyl_trans PF02574.11 EMC86071.1 - 1.8e-100 336.1 0.0 3.5e-100 335.2 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 EMC86071.1 - 2.9e-83 278.2 0.0 4.6e-83 277.5 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 EMC86071.1 - 2.4e-43 147.9 0.3 2.9e-41 141.1 0.0 2.8 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.12 EMC86071.1 - 8.6e-21 73.7 0.1 4.8e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 EMC86071.1 - 3.6e-17 62.3 0.1 1e-16 60.8 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.11 EMC86071.1 - 0.0038 15.7 0.0 0.0072 14.8 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit IPT PF01745.11 EMC86071.1 - 0.057 12.5 0.1 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Isopentenyl transferase RYDR_ITPR PF01365.16 EMC86073.1 - 1.1e-134 446.1 2.8 2.9e-69 232.4 1.0 3.5 3 0 0 3 3 3 2 RIH domain RyR PF02026.11 EMC86073.1 - 4.6e-133 433.6 7.4 6e-34 115.9 1.7 5.1 4 0 0 4 4 4 4 RyR domain RR_TM4-6 PF06459.7 EMC86073.1 - 8.3e-85 284.9 1.5 8.3e-85 284.9 1.1 2.6 4 0 0 4 4 2 1 Ryanodine Receptor TM 4-6 SPRY PF00622.23 EMC86073.1 - 4.8e-75 249.5 4.3 6.7e-25 87.5 0.1 3.8 3 0 0 3 3 3 3 SPRY domain Ins145_P3_rec PF08709.6 EMC86073.1 - 8.5e-53 178.5 0.0 5.3e-50 169.4 0.0 3.0 3 0 0 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.14 EMC86073.1 - 9.7e-50 168.7 0.1 1.2e-48 165.1 0.0 2.8 3 0 0 3 3 3 1 MIR domain RIH_assoc PF08454.6 EMC86073.1 - 2.7e-41 139.6 1.4 1.4e-39 134.1 0.6 3.6 3 1 0 3 3 3 1 RyR and IP3R Homology associated Ion_trans PF00520.26 EMC86073.1 - 1.1e-08 34.5 7.8 1.1e-08 34.5 5.4 2.6 3 1 0 3 3 3 1 Ion transport protein EF-hand_7 PF13499.1 EMC86073.1 - 1.5e-07 31.3 0.9 7.6e-07 29.1 0.6 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC86073.1 - 8.3e-06 25.3 0.2 4.7e-05 22.9 0.1 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC86073.1 - 9.3e-05 21.4 0.3 0.0015 17.6 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EMC86073.1 - 0.0029 17.3 0.3 0.015 15.1 0.0 2.4 2 0 0 2 2 1 1 EF-hand domain YjfB_motility PF14070.1 EMC86073.1 - 0.021 14.6 6.5 0.066 13.0 4.5 1.9 1 0 0 1 1 1 0 Putative motility protein 7tm_1 PF00001.16 EMC86074.1 - 3.7e-86 288.4 12.0 8.4e-86 287.2 8.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86074.1 - 3.4e-09 36.2 5.1 3.4e-09 36.2 3.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC86074.1 - 4e-07 29.4 6.3 4e-07 29.4 4.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx LETM1 PF07766.8 EMC86074.1 - 0.047 12.7 0.2 0.58 9.1 0.1 2.2 2 0 0 2 2 2 0 LETM1-like protein FH2 PF02181.18 EMC86075.1 - 1.2e-102 343.5 10.6 1.2e-102 343.5 7.3 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain DAN PF03045.10 EMC86076.1 - 1e-40 137.9 11.4 1.3e-40 137.6 7.9 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 EMC86076.1 - 6.4e-05 22.9 8.0 9.4e-05 22.4 5.5 1.2 1 0 0 1 1 1 1 Cystine-knot domain TIR_2 PF13676.1 EMC86076.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 TIR domain RGS PF00615.14 EMC86077.1 - 3.6e-35 120.6 0.3 1.1e-34 119.0 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EMC86077.1 - 6.8e-17 60.9 0.0 3e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 EMC86077.1 - 6.1e-16 57.9 0.1 1.6e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.6 EMC86077.1 - 0.047 13.1 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain 7tm_1 PF00001.16 EMC86078.1 - 7.7e-40 136.6 21.0 1e-39 136.2 14.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86078.1 - 0.00027 20.1 11.6 0.019 14.1 0.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Herpes_UL49_5 PF05702.6 EMC86078.1 - 0.032 14.0 1.1 2.2 8.2 0.1 3.0 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein WD40 PF00400.27 EMC86079.1 - 0.034 14.0 2.8 8.4 6.4 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.27 EMC86080.1 - 1.5e-07 31.0 0.7 0.01 15.6 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC86080.1 - 0.024 13.4 0.0 0.076 11.7 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like FGase PF05013.7 EMC86081.1 - 3.2e-05 23.9 0.0 0.0055 16.6 0.0 2.5 2 1 0 2 2 2 2 N-formylglutamate amidohydrolase Mito_morph_reg PF14972.1 EMC86081.1 - 0.072 12.4 1.6 0.42 10.0 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial morphogenesis regulator XPG_I PF00867.13 EMC86082.1 - 6.6e-27 93.4 0.1 2.4e-26 91.6 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMC86082.1 - 1.2e-22 80.0 0.0 3.3e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EMC86082.1 - 0.00064 19.2 0.1 0.00064 19.2 0.1 2.0 2 0 0 2 2 2 1 XPG domain containing Atg8 PF02991.11 EMC86083.1 - 2.5e-39 133.4 0.3 2.8e-39 133.2 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMC86083.1 - 4.6e-06 26.7 0.1 5.6e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PLDc_3 PF13918.1 EMC86085.1 - 7e-68 227.5 1.2 7.4e-68 227.4 0.1 1.6 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.1 EMC86085.1 - 6.9e-13 48.4 0.1 6.1e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC86085.1 - 5.8e-09 35.4 0.9 9.1e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1669 PF07894.7 EMC86085.1 - 0.023 13.8 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) CEP170_C PF15308.1 EMC86087.1 - 9.8e-253 840.4 63.0 9.8e-253 840.4 43.7 3.9 4 0 0 4 4 4 1 CEP170 C-terminus FHA PF00498.21 EMC86087.1 - 6.7e-14 51.7 0.0 6.7e-14 51.7 0.0 2.5 3 0 0 3 3 3 1 FHA domain Macoilin PF09726.4 EMC86088.1 - 0.00032 19.1 38.8 0.00032 19.1 26.9 3.1 1 1 2 3 3 3 2 Transmembrane protein Spc24 PF08286.6 EMC86088.1 - 0.05 13.3 0.2 0.05 13.3 0.2 8.6 4 1 4 8 8 8 0 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 EMC86088.1 - 2 7.5 23.7 0.4 9.8 2.1 4.5 1 1 5 6 6 6 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EMC86088.1 - 5.5 6.8 111.6 0.036 13.9 6.8 8.2 4 1 5 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.20 EMC86089.1 - 9.7e-76 254.3 0.1 3.2e-75 252.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86089.1 - 1.2e-36 126.1 0.0 1.6e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC86089.1 - 5.3e-08 32.1 0.0 1.3e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 EMC86089.1 - 6.2e-08 32.7 0.2 2.9e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.19 EMC86089.1 - 3.7e-07 30.5 2.3 7.2e-07 29.6 1.6 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.1 EMC86089.1 - 0.1 12.8 0.8 2.4 8.4 0.6 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain BTB PF00651.26 EMC86090.1 - 2.9e-27 94.8 1.2 5.2e-27 94.0 0.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC86090.1 - 8e-18 63.7 23.0 3.6e-08 33.2 1.4 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC86090.1 - 5.5e-13 48.4 35.0 0.0015 18.7 1.6 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC86090.1 - 5.3e-12 45.1 29.4 0.0053 16.9 1.9 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC86090.1 - 0.00013 22.0 17.2 0.011 15.9 0.0 5.0 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC86090.1 - 0.0016 18.5 0.1 0.0016 18.5 0.1 5.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC86090.1 - 0.011 15.6 22.8 0.099 12.5 0.8 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger GAGA PF09237.6 EMC86090.1 - 0.018 14.5 6.3 0.45 10.1 0.2 3.5 2 1 1 3 3 3 0 GAGA factor zinc_ribbon_5 PF13719.1 EMC86090.1 - 0.23 11.0 3.5 44 3.7 0.0 3.8 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.1 EMC86090.1 - 0.53 10.2 6.4 2.6 8.0 0.5 2.8 2 0 0 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.1 EMC86090.1 - 0.9 9.2 5.0 36 4.1 0.0 3.8 3 0 0 3 3 3 0 zinc-ribbon domain RRN7 PF11781.3 EMC86090.1 - 3.2 7.3 6.3 5.5 6.5 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Adenylsucc_synt PF00709.16 EMC86092.1 - 1.7e-145 484.8 0.0 2.1e-145 484.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Spore_YpjB PF09577.5 EMC86092.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Peptidase_C97 PF05903.9 EMC86093.1 - 4.3e-39 133.7 0.0 5.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain YxiJ PF14176.1 EMC86093.1 - 0.051 13.6 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 YxiJ-like protein RNase_H2-Ydr279 PF09468.5 EMC86093.1 - 0.054 12.6 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LRAT PF04970.8 EMC86093.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF3767 PF12597.3 EMC86094.1 - 5.5e-15 55.0 0.1 6.8e-15 54.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Vitelline_membr PF10542.4 EMC86094.1 - 0.037 13.6 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region SPRY PF00622.23 EMC86095.1 - 6.2e-25 87.6 0.3 6.2e-25 87.6 0.2 2.5 3 0 0 3 3 3 1 SPRY domain AAA_33 PF13671.1 EMC86095.1 - 7e-23 81.0 0.1 1.5e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMC86095.1 - 4.6e-05 22.6 0.2 8.8e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 EMC86095.1 - 0.013 16.3 0.0 0.047 14.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMC86095.1 - 0.018 14.4 0.3 0.031 13.7 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain EF-hand_7 PF13499.1 EMC86096.1 - 1.8e-12 47.2 0.0 1.8e-08 34.3 0.0 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC86096.1 - 1.1e-11 43.6 0.1 0.00031 20.3 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EMC86096.1 - 5.6e-08 31.5 1.4 0.0062 15.7 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EMC86096.1 - 5.4e-07 29.4 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC86096.1 - 1.6e-06 27.5 0.0 0.00092 18.7 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EFhand_Ca_insen PF08726.5 EMC86096.1 - 0.0013 18.6 0.4 0.0022 17.9 0.1 1.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 EMC86096.1 - 0.011 15.0 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 0 EF hand TFIIE_beta PF02186.10 EMC86096.1 - 0.022 14.7 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 TFIIE beta subunit core domain zf-MYND PF01753.13 EMC86098.1 - 1.6e-05 24.6 3.2 1.6e-05 24.6 2.2 2.3 2 0 0 2 2 2 1 MYND finger Consortin_C PF15281.1 EMC86099.1 - 1.3e-56 189.0 0.1 3.4e-56 187.7 0.0 1.7 1 0 0 1 1 1 1 Consortin C-terminus TPR_7 PF13176.1 EMC86099.1 - 0.019 14.7 0.3 0.21 11.4 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Saccharop_dh PF03435.13 EMC86100.1 - 4.1e-46 157.7 0.0 4.8e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase ELYS PF13934.1 EMC86101.1 - 3.9e-10 39.8 0.5 7.2e-10 38.9 0.3 1.4 1 0 0 1 1 1 1 Nuclear pore complex assembly Rpr2 PF04032.11 EMC86103.1 - 0.02 14.7 0.9 0.02 14.7 0.6 2.2 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glycos_transf_2 PF00535.21 EMC86104.1 - 1.6e-34 119.0 0.0 2.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC86104.1 - 2.6e-24 85.5 2.5 4.8e-24 84.7 1.4 1.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC86104.1 - 3.7e-11 43.2 0.0 5.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC86104.1 - 7.1e-07 28.5 0.1 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC86104.1 - 6e-05 22.2 0.0 0.00062 18.9 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 EMC86104.1 - 0.0014 18.9 0.2 0.92 9.9 0.0 2.7 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_trans_2_3 PF13632.1 EMC86104.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family group 2 YL1_C PF08265.6 EMC86105.1 - 6.9e-09 35.1 4.7 2.9e-06 26.7 0.1 3.1 4 0 0 4 4 4 2 YL1 nuclear protein C-terminal domain SMC_hinge PF06470.8 EMC86108.1 - 1.1e-16 60.8 0.2 4.5e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SlyX PF04102.7 EMC86108.1 - 0.0076 16.5 4.3 0.0076 16.5 3.0 7.4 4 2 1 6 6 6 1 SlyX Reo_sigmaC PF04582.7 EMC86108.1 - 0.11 11.6 5.0 0.83 8.7 0.1 3.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Complex1_LYR_1 PF13232.1 EMC86109.1 - 3e-12 46.5 1.4 3.2e-12 46.4 1.0 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMC86109.1 - 1.6e-11 43.8 1.6 1.7e-11 43.7 1.1 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EntA_Immun PF08951.5 EMC86109.1 - 0.015 15.4 0.2 0.017 15.2 0.2 1.0 1 0 0 1 1 1 0 Enterocin A Immunity cwf21 PF08312.7 EMC86109.1 - 0.12 12.2 0.3 0.13 12.1 0.2 1.1 1 0 0 1 1 1 0 cwf21 domain Ribonuc_P_40 PF08584.6 EMC86111.1 - 6.9e-97 323.8 0.0 8e-97 323.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit ECH PF00378.15 EMC86112.1 - 1.5e-35 122.5 1.0 1.6e-35 122.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Chromo PF00385.19 EMC86112.1 - 1.5e-18 66.2 3.2 3.1e-18 65.1 2.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EMC86112.1 - 0.021 14.5 0.9 0.021 14.5 0.6 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain PWWP PF00855.12 EMC86112.1 - 0.52 10.5 2.8 2 8.6 1.6 2.3 2 1 0 2 2 2 0 PWWP domain ECH PF00378.15 EMC86113.1 - 3.9e-41 140.8 0.1 6.9e-41 139.9 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ACBP PF00887.14 EMC86113.1 - 5.2e-30 102.9 0.3 9.6e-30 102.1 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein TPR_21 PF09976.4 EMC86113.1 - 0.065 13.1 1.9 0.15 11.9 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 EMC86114.1 - 2.3e-48 164.6 0.6 2.3e-48 164.6 0.4 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86114.1 - 1.1e-22 80.3 0.1 3.8e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMC86114.1 - 0.0022 16.8 0.5 0.0044 15.8 0.2 1.5 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase zf-H2C2_2 PF13465.1 EMC86115.1 - 0.0052 17.0 0.2 0.0052 17.0 0.2 2.0 2 1 0 2 2 2 1 Zinc-finger double domain PX PF00787.19 EMC86116.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 PX domain Sugar_tr PF00083.19 EMC86117.1 - 2.2e-18 66.0 18.8 3e-18 65.6 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC86117.1 - 9.1e-15 54.2 20.9 2e-12 46.5 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rieske PF00355.21 EMC86117.1 - 0.098 12.2 0.3 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain RepB-RCR_reg PF10723.4 EMC86118.1 - 0.051 13.3 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Replication regulatory protein RepB Tubulin PF00091.20 EMC86119.1 - 5.7e-71 238.7 0.0 8.7e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC86119.1 - 8.3e-51 171.2 0.1 1.4e-50 170.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMC86119.1 - 6.2e-06 26.2 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMC86119.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Abhydrolase_6 PF12697.2 EMC86120.1 - 2e-28 99.8 0.0 2.3e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC86120.1 - 2.8e-19 69.5 0.0 3.8e-13 49.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC86120.1 - 3.1e-16 59.4 0.0 8e-16 58.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMC86120.1 - 0.00079 18.7 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EMC86120.1 - 0.0015 17.8 0.0 0.016 14.4 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMC86120.1 - 0.0027 17.2 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 EMC86120.1 - 0.0036 16.7 0.1 0.021 14.2 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EMC86120.1 - 0.0045 16.7 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EMC86120.1 - 0.0048 16.7 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EMC86120.1 - 0.048 13.0 0.1 0.2 11.0 0.0 1.9 1 1 0 2 2 2 0 Putative esterase LIP PF03583.9 EMC86120.1 - 0.13 11.4 0.1 5.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Pkinase PF00069.20 EMC86121.1 - 6.4e-54 182.8 0.1 9.6e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86121.1 - 4.9e-52 176.5 0.1 6.7e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.17 EMC86121.1 - 9.9e-20 70.1 0.7 3e-19 68.5 0.2 2.1 2 0 0 2 2 2 1 Death domain RHIM PF12721.2 EMC86121.1 - 1e-08 35.4 2.7 1e-08 35.4 1.9 3.1 3 1 0 3 3 3 1 RIP homotypic interaction motif Kinase-like PF14531.1 EMC86121.1 - 4e-05 22.7 0.0 6.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC86121.1 - 0.0052 16.1 0.1 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMC86121.1 - 0.19 11.4 0.1 1.1 8.9 0.0 2.2 3 1 0 3 3 3 0 Phosphotransferase enzyme family Flavodoxin_2 PF02525.12 EMC86122.1 - 5e-51 173.0 0.0 5.7e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EMC86122.1 - 1.8e-12 47.0 0.0 2.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EMC86122.1 - 0.0097 15.2 0.1 0.016 14.5 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin IRF-3 PF10401.4 EMC86123.1 - 3.7e-62 209.1 0.3 5e-62 208.6 0.2 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 EMC86123.1 - 4.4e-46 155.2 0.2 6.8e-46 154.5 0.1 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Sec5 PF15469.1 EMC86124.1 - 2.1e-56 190.5 0.2 1e-55 188.2 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.19 EMC86124.1 - 4.5e-08 32.9 0.4 9.4e-08 31.9 0.3 1.6 1 0 0 1 1 1 1 IPT/TIG domain SAM_2 PF07647.12 EMC86124.1 - 0.031 14.1 0.1 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4618 PF15397.1 EMC86124.1 - 0.086 12.1 3.8 1.1 8.5 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Epimerase PF01370.16 EMC86126.1 - 1.7e-58 197.8 0.0 1.9e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC86126.1 - 2.6e-06 26.5 0.0 2.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Pkinase PF00069.20 EMC86128.1 - 9.3e-70 234.7 0.0 1.1e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86128.1 - 1.3e-39 135.8 0.0 1.5e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC86128.1 - 4.1e-06 26.0 0.1 6.4e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC86128.1 - 0.0027 17.0 0.6 0.004 16.5 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EMC86128.1 - 0.0042 16.0 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EMC86128.1 - 0.026 14.1 1.3 0.044 13.3 0.9 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EMC86128.1 - 0.053 13.2 0.0 1.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC86128.1 - 0.061 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MgsA_C PF12002.3 EMC86129.1 - 1.1e-60 204.2 0.0 5.7e-60 201.8 0.0 1.9 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EMC86129.1 - 2.2e-09 37.5 0.4 4.2e-09 36.6 0.3 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMC86129.1 - 3.4e-07 29.5 0.4 0.00047 19.2 0.0 2.2 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EMC86129.1 - 0.0041 16.6 0.1 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 EMC86129.1 - 0.015 14.9 0.3 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.1 EMC86129.1 - 0.033 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Serpin PF00079.15 EMC86130.1 - 2.5e-46 158.5 0.0 2.7e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Acetyltransf_13 PF13880.1 EMC86131.1 - 8.5e-32 108.7 0.0 1.8e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EMC86131.1 - 5.3e-17 61.1 0.1 1.1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Abhydrolase_6 PF12697.2 EMC86132.1 - 1.6e-11 44.5 0.0 2.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC86132.1 - 7e-09 35.5 0.0 2.4e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC86132.1 - 1.2e-06 28.3 0.0 3.6e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMC86132.1 - 0.017 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ank PF00023.25 EMC86133.1 - 5.9e-55 180.4 16.8 2.2e-08 33.4 0.0 9.7 10 1 0 10 10 10 8 Ankyrin repeat Ank_2 PF12796.2 EMC86133.1 - 4.9e-54 180.6 17.6 1.3e-16 60.6 0.0 5.7 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) MIB_HERC2 PF06701.8 EMC86133.1 - 7.4e-51 170.0 17.0 3.3e-28 97.4 3.2 3.8 3 0 0 3 3 3 2 Mib_herc2 Ank_5 PF13857.1 EMC86133.1 - 1e-47 159.0 16.3 3e-12 46.3 0.0 7.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC86133.1 - 1.6e-42 143.1 24.6 1.5e-11 44.4 0.1 7.6 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86133.1 - 1.1e-31 105.7 17.9 0.00031 20.6 0.0 10.0 11 0 0 11 11 11 6 Ankyrin repeat zf-C3HC4_3 PF13920.1 EMC86133.1 - 7.3e-28 95.9 60.0 4.6e-11 42.2 9.5 4.7 4 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.12 EMC86133.1 - 5.1e-11 41.9 8.2 5.1e-11 41.9 5.7 3.5 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.1 EMC86133.1 - 7.8e-05 22.6 61.7 0.002 18.0 7.0 5.0 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) GATA PF00320.22 EMC86134.1 - 2.8e-30 103.3 19.7 3.2e-16 58.3 2.9 2.8 3 0 0 3 3 3 2 GATA zinc finger GATA-N PF05349.7 EMC86134.1 - 4.3e-09 36.7 3.3 4.3e-09 36.7 2.3 2.5 2 1 0 2 2 2 1 GATA-type transcription activator, N-terminal TF_Zn_Ribbon PF08271.7 EMC86134.1 - 2.4e-07 29.9 5.7 0.0023 17.1 0.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EMC86134.1 - 0.001 18.9 1.1 0.43 10.5 0.2 3.3 3 0 0 3 3 3 1 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 EMC86134.1 - 0.016 14.8 4.1 0.85 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.8 EMC86134.1 - 0.06 13.0 5.3 1 9.0 0.0 2.8 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.7 EMC86134.1 - 0.082 12.9 5.8 0.21 11.6 0.5 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.2 EMC86134.1 - 0.1 12.4 7.9 2.7 7.8 4.9 2.8 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EMC86134.1 - 0.88 9.2 13.2 0.15 11.7 0.3 3.2 3 1 0 3 3 3 0 Putative transposase DNA-binding domain DUF2387 PF09526.5 EMC86134.1 - 1.2 9.1 5.7 7.3 6.5 0.1 2.8 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) Cytochrom_c3_2 PF14537.1 EMC86134.1 - 4.2 7.7 7.1 1.3 9.3 1.6 2.2 1 1 2 3 3 3 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EMC86134.1 - 5.3 6.7 10.0 2.4 7.8 3.4 2.5 1 1 2 3 3 3 0 Cytochrome c7 Zn_Tnp_IS1595 PF12760.2 EMC86134.1 - 8.3 6.3 12.5 0.42 10.4 0.2 2.9 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Cyclin_N PF00134.18 EMC86135.1 - 3.4e-08 33.1 0.2 4.7e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF457 PF04307.9 EMC86136.1 - 2.4 7.4 8.8 2.7 7.2 5.0 2.1 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Mic1 PF07035.7 EMC86137.1 - 4.9e-75 250.5 1.2 6.1e-75 250.1 0.2 1.6 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like Patched PF02460.13 EMC86138.1 - 1.5e-84 284.4 25.8 2.7e-83 280.3 18.1 2.4 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.3 EMC86138.1 - 2.1e-55 186.3 6.5 2.1e-55 186.3 4.5 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EMC86138.1 - 0.00028 19.7 4.9 0.00028 19.7 3.4 2.4 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.14 EMC86138.1 - 0.00039 18.0 7.5 0.00039 18.0 5.2 2.1 2 1 0 2 2 2 1 AcrB/AcrD/AcrF family Ank_2 PF12796.2 EMC86140.1 - 1.9e-146 476.7 45.2 5.8e-20 71.4 0.7 9.4 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86140.1 - 9.8e-129 413.2 48.1 1.5e-08 33.9 0.1 19.6 19 0 0 19 19 19 19 Ankyrin repeat Ank_4 PF13637.1 EMC86140.1 - 4.9e-104 339.0 28.7 1.3e-10 41.4 0.0 15.1 3 2 12 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86140.1 - 6e-92 292.2 25.4 1.3e-06 28.0 0.0 19.2 20 0 0 20 20 20 17 Ankyrin repeat Ank_5 PF13857.1 EMC86140.1 - 5.6e-87 283.8 42.5 7.6e-10 38.7 0.2 14.5 5 4 9 15 15 15 14 Ankyrin repeats (many copies) NACHT PF05729.7 EMC86140.1 - 0.014 15.0 0.3 0.12 12.0 0.2 2.4 1 1 0 1 1 1 0 NACHT domain DUF249 PF03158.8 EMC86140.1 - 0.026 14.0 0.0 14 5.1 0.0 4.0 4 1 0 4 4 4 0 Multigene family 530 protein AAA_17 PF13207.1 EMC86140.1 - 0.1 13.4 0.1 1.9 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMC86140.1 - 0.13 12.4 0.0 0.51 10.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cadherin PF00028.12 EMC86141.1 - 0 2049.7 52.6 5.7e-25 87.3 0.3 34.6 34 1 0 34 34 34 34 Cadherin domain Cadherin_2 PF08266.7 EMC86141.1 - 3.3e-43 145.1 0.0 0.049 13.2 0.0 23.0 23 2 0 23 23 23 9 Cadherin-like Laminin_G_2 PF02210.19 EMC86141.1 - 7.8e-43 145.5 0.4 7e-20 71.3 0.0 3.5 3 0 0 3 3 3 2 Laminin G domain Laminin_G_1 PF00054.18 EMC86141.1 - 1.5e-32 112.4 0.1 2e-17 63.4 0.0 3.2 3 0 0 3 3 3 2 Laminin G domain EGF PF00008.22 EMC86141.1 - 1.5e-22 79.1 95.7 4.4e-07 29.7 7.1 7.4 7 1 0 7 7 7 6 EGF-like domain EGF_CA PF07645.10 EMC86141.1 - 4.3e-10 39.4 25.7 4.2e-07 29.8 4.7 7.5 5 2 2 7 7 7 2 Calcium-binding EGF domain EGF_3 PF12947.2 EMC86141.1 - 0.00081 19.2 1.1 0.00081 19.2 0.8 6.3 6 0 0 6 6 6 2 EGF domain EGF_2 PF07974.8 EMC86141.1 - 0.031 14.4 106.5 0.02 15.0 9.7 7.7 7 0 0 7 7 7 0 EGF-like domain hEGF PF12661.2 EMC86141.1 - 0.044 13.8 56.2 0.1 12.6 1.1 6.8 7 0 0 7 7 7 0 Human growth factor-like EGF HSP70 PF00012.15 EMC86142.1 - 9.3e-174 578.6 7.6 2.1e-164 547.7 0.0 2.9 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EMC86142.1 - 2.5e-08 32.8 0.0 6e-08 31.6 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein Pkinase PF00069.20 EMC86143.1 - 5.2e-72 242.1 0.1 8.2e-72 241.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86143.1 - 3.3e-46 157.4 0.0 5.8e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EMC86143.1 - 1.3e-13 50.7 0.0 6.2e-12 45.3 0.0 2.9 2 0 0 2 2 2 1 POLO box duplicated region Kinase-like PF14531.1 EMC86143.1 - 0.001 18.1 0.0 0.002 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF4520 PF15016.1 EMC86143.1 - 0.027 14.0 0.0 0.27 10.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) Kdo PF06293.9 EMC86143.1 - 0.1 11.6 0.2 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC86143.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EMC86144.1 - 2e-37 128.7 29.8 1.7e-30 105.9 12.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC86144.1 - 5.5e-09 35.1 10.9 5.5e-09 35.1 7.6 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter DUF2048 PF09752.4 EMC86145.1 - 1.7e-158 527.0 0.0 2e-158 526.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 EMC86145.1 - 4.3e-06 26.7 0.0 5.3e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMC86145.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EMC86145.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family La PF05383.12 EMC86146.1 - 6.6e-23 80.2 0.1 1.4e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 La domain API5 PF05918.6 EMC86146.1 - 4.8 5.5 8.9 7.6 4.8 6.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cyt-b5 PF00173.23 EMC86147.1 - 0.0017 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HC5HC2H_2 PF13832.1 EMC86148.1 - 1.1e-33 115.5 3.0 1.1e-33 115.5 2.1 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMC86148.1 - 3.6e-28 97.5 2.2 3.6e-28 97.5 1.5 4.0 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 EMC86148.1 - 1.5e-20 74.0 0.1 1.5e-20 74.0 0.1 3.6 3 2 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 EMC86148.1 - 5.2e-13 48.0 6.3 5.2e-13 48.0 4.4 3.7 3 1 1 4 4 4 1 PHD-finger PHD PF00628.24 EMC86148.1 - 1.1e-11 44.1 23.3 1.1e-09 37.7 6.2 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EMC86148.1 - 0.0021 17.7 3.5 0.0021 17.7 2.4 3.3 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EMC86148.1 - 0.0061 16.5 2.8 0.0061 16.5 1.9 3.6 2 1 1 3 3 3 1 RING-like domain Prok-RING_1 PF14446.1 EMC86148.1 - 0.046 13.4 15.3 0.94 9.2 1.1 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HisKA_3 PF07730.8 EMC86149.1 - 0.17 12.2 0.3 0.17 12.2 0.2 9.0 5 2 5 10 10 10 0 Histidine kinase DUF2576 PF10845.3 EMC86149.1 - 0.51 9.5 3.8 20 4.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) C2 PF00168.25 EMC86152.1 - 5.8e-23 80.5 0.0 7.3e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain Pea-VEAacid PF08111.6 EMC86155.1 - 6.6e-09 35.2 25.2 1e+03 0.2 0.0 21.9 27 0 0 27 27 27 0 Pea-VEAacid family CLPTM1 PF05602.7 EMC86157.1 - 4.6e-107 358.4 1.6 5.8e-107 358.1 1.1 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EMC86157.1 - 0.00031 20.2 3.4 0.0079 15.7 0.3 2.7 2 0 0 2 2 2 2 PQ loop repeat NAD_kinase PF01513.16 EMC86160.1 - 3.6e-09 35.8 0.0 6.4e-08 31.7 0.0 2.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EMC86160.1 - 0.0028 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Not3 PF04065.10 EMC86160.1 - 0.17 11.1 0.3 0.3 10.3 0.2 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component F-box-like PF12937.2 EMC86161.1 - 9.1e-16 57.3 2.9 2.8e-15 55.7 2.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC86161.1 - 4.7e-09 35.6 0.9 4.7e-09 35.6 0.6 2.2 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 EMC86161.1 - 2.8e-08 33.0 10.4 3.3 8.0 0.0 7.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 EMC86161.1 - 3.3e-05 23.3 12.1 10 6.5 0.0 7.3 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 EMC86161.1 - 0.0087 15.6 7.2 3.8 7.2 1.2 4.9 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.1 EMC86161.1 - 0.082 12.6 1.1 0.23 11.2 0.8 1.9 1 1 0 1 1 1 0 F-box-like domain LRR_7 PF13504.1 EMC86161.1 - 2.6 8.6 13.0 12 6.6 0.0 7.2 7 2 1 8 8 8 0 Leucine rich repeat LMBR1 PF04791.11 EMC86162.1 - 2.5e-103 346.2 18.5 2.5e-103 346.2 12.8 1.3 2 0 0 2 2 2 1 LMBR1-like membrane protein EF-hand_1 PF00036.27 EMC86163.1 - 6e-25 84.6 11.1 2.7e-09 35.6 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EMC86163.1 - 2.2e-23 79.9 7.5 3.1e-07 29.7 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EMC86163.1 - 1.5e-18 66.6 10.4 5e-09 36.1 3.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC86163.1 - 1.8e-16 58.6 13.7 1.2e-05 24.4 2.6 5.0 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 EMC86163.1 - 1.7e-13 49.9 13.2 5.2e-08 32.3 0.8 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EMC86163.1 - 0.0001 21.9 2.2 0.071 12.8 0.1 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMC86163.1 - 0.051 13.2 1.6 0.32 10.6 0.4 2.7 3 1 1 4 4 4 0 EF hand EF-hand_9 PF14658.1 EMC86163.1 - 0.083 12.8 1.6 2.7 7.9 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain UPF0139 PF03669.8 EMC86164.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) DUF1042 PF06294.6 EMC86165.1 - 1.7e-07 30.9 4.4 3.1e-07 30.1 0.1 2.1 1 1 0 2 2 2 1 Domain of Unknown Function (DUF1042) HTH_Tnp_IS630 PF01710.11 EMC86165.1 - 0.013 15.2 0.4 0.013 15.2 0.3 2.0 1 1 1 2 2 2 0 Transposase DUF2321 PF10083.4 EMC86165.1 - 0.053 13.0 0.2 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) MRC1 PF09444.5 EMC86165.1 - 0.62 10.3 5.9 0.17 12.1 1.7 1.7 2 0 0 2 2 2 0 MRC1-like domain DUF1690 PF07956.6 EMC86165.1 - 0.91 9.4 6.1 0.15 12.0 1.0 1.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) EpoR_lig-bind PF09067.5 EMC86166.1 - 3.7e-52 174.6 0.1 4.3e-27 94.1 0.0 2.6 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding fn3 PF00041.16 EMC86166.1 - 1.6e-26 92.2 14.0 5.1e-10 39.3 0.9 5.0 5 0 0 5 5 5 4 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC86166.1 - 3.1e-21 75.3 0.5 8.6e-10 38.6 0.0 3.0 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 EMC86166.1 - 0.0059 16.3 8.6 1 9.0 0.0 4.4 5 0 0 5 5 5 2 Tissue factor Aminotran_3 PF00202.16 EMC86167.1 - 3.4e-84 282.6 0.0 4.2e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMC86167.1 - 0.0036 16.3 0.0 0.1 11.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II zf-C2H2_jaz PF12171.3 EMC86168.1 - 2.4e-10 40.2 3.4 2.8e-10 40.0 0.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DnaJ PF00226.26 EMC86168.1 - 2e-08 33.8 0.4 2e-08 33.8 0.3 2.6 2 1 0 2 2 2 1 DnaJ domain zf-met PF12874.2 EMC86168.1 - 1.6e-07 31.3 2.9 6.4e-07 29.3 0.8 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC86168.1 - 3.6e-07 30.2 1.2 0.024 14.7 0.1 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EMC86168.1 - 0.0041 17.3 4.4 1.5 9.3 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC86168.1 - 0.079 13.3 7.0 0.5 10.8 0.6 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type AKAP95 PF04988.7 EMC86168.1 - 4.9 6.8 22.5 2.6 7.7 5.3 3.8 3 2 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) C1q PF00386.16 EMC86169.1 - 1.9e-32 111.9 3.7 2.4e-32 111.6 2.6 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC86169.1 - 1.2e-11 43.9 50.7 2.4e-10 39.8 22.5 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 EMC86170.1 - 2.8e-18 65.7 34.9 6.6e-14 51.3 7.0 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EMC86170.1 - 4.2e-18 64.9 14.7 2.7e-17 62.2 10.2 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein DUF3382 PF11862.3 EMC86170.1 - 0.64 9.9 0.0 0.64 9.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) 7tm_1 PF00001.16 EMC86171.1 - 5.2e-53 179.8 16.1 6.8e-53 179.4 11.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0182 PF03699.8 EMC86171.1 - 1.9 6.3 9.6 2.3 6.0 6.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Leuk-A4-hydro_C PF09127.6 EMC86173.1 - 1.3e-14 54.0 1.8 1.8e-14 53.5 0.3 1.9 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.15 EMC86173.1 - 8.9e-14 51.3 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EMC86173.1 - 6.7e-12 45.5 1.3 1.9e-11 44.1 0.6 2.0 2 1 0 2 2 2 1 Peptidase MA superfamily DLH PF01738.13 EMC86173.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_M61 PF05299.7 EMC86173.1 - 0.054 13.4 1.5 0.48 10.4 1.0 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF4256 PF14066.1 EMC86173.1 - 0.63 9.5 3.1 6.2 6.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) Fanconi_C PF02106.10 EMC86174.1 - 9.7e-271 899.0 19.2 1.1e-270 898.9 13.3 1.0 1 0 0 1 1 1 1 Fanconi anaemia group C protein Patched PF02460.13 EMC86175.1 - 4.1e-75 253.2 18.7 3.9e-44 150.7 0.9 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EMC86175.1 - 2.7e-46 156.8 4.9 2.7e-46 156.8 3.4 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MENTAL PF10457.4 EMC86175.1 - 1.6 8.2 7.1 3.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Cholesterol-capturing domain SNF2_N PF00176.18 EMC86176.1 - 3.5e-59 200.0 0.4 5e-59 199.5 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC86176.1 - 3.6e-17 61.9 0.1 5.2e-16 58.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC86176.1 - 1.3e-08 34.5 0.0 3.2e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EMC86176.1 - 9e-08 31.2 0.0 2.4e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EMC86176.1 - 4e-07 30.0 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SMN PF06003.7 EMC86176.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Oxidored_nitro PF00148.14 EMC86176.1 - 0.085 11.4 0.0 0.24 9.9 0.0 1.7 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TPT PF03151.11 EMC86177.1 - 2.7e-10 40.0 9.6 2.7e-10 40.0 6.6 2.9 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EMC86177.1 - 5e-05 22.3 19.3 7.1e-05 21.8 13.4 1.2 1 0 0 1 1 1 1 UAA transporter family HABP4_PAI-RBP1 PF04774.10 EMC86178.1 - 3.1e-13 50.1 3.7 3.1e-13 50.1 2.5 2.0 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family DSPn PF14671.1 EMC86179.1 - 6.4e-56 188.2 3.6 1.6e-54 183.6 1.3 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EMC86179.1 - 3.5e-16 59.0 0.0 7.2e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC86179.1 - 8.3e-06 25.3 0.1 2.3e-05 23.8 0.0 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC86179.1 - 3.6e-05 23.8 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC86179.1 - 0.0022 18.2 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EMC86179.1 - 0.074 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family AhpC-TSA_2 PF13911.1 EMC86180.1 - 5.1e-20 71.5 0.0 6.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMC86180.1 - 0.0016 18.1 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMC86180.1 - 0.0074 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Lipoprotein_20 PF13942.1 EMC86181.1 - 0.029 13.8 1.3 0.032 13.7 0.9 1.0 1 0 0 1 1 1 0 YfhG lipoprotein MIT PF04212.13 EMC86181.1 - 0.089 12.6 1.5 0.11 12.4 1.0 1.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF2407_C PF13373.1 EMC86181.1 - 0.16 11.8 1.5 0.17 11.7 1.0 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain CFC PF09443.5 EMC86182.1 - 6.9e-15 54.3 9.5 6.9e-15 54.3 6.6 2.3 2 0 0 2 2 2 1 Cripto_Frl-1_Cryptic (CFC) EGF PF00008.22 EMC86182.1 - 0.011 15.6 7.3 0.033 14.1 5.1 1.9 1 0 0 1 1 1 0 EGF-like domain LRR_4 PF12799.2 EMC86183.1 - 8.7e-27 92.2 22.2 6.5e-09 35.2 1.1 5.2 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC86183.1 - 8.1e-25 86.3 26.5 1.9e-09 37.0 1.8 4.6 2 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 EMC86183.1 - 3.9e-18 62.6 19.5 0.0015 18.2 0.2 7.5 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC86183.1 - 2.2e-11 42.0 15.6 0.24 11.7 0.0 7.4 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EMC86183.1 - 1.1e-09 37.2 17.6 0.1 12.7 0.2 7.3 7 0 0 7 7 7 3 Leucine Rich repeat Cmyb_C PF09316.5 EMC86183.1 - 0.45 10.1 4.2 0.41 10.2 0.2 2.4 2 0 0 2 2 2 0 C-myb, C-terminal Yae1_N PF09811.4 EMC86184.1 - 2e-13 49.6 39.6 1.8e+03 -1.5 27.5 4.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Laminin_G_2 PF02210.19 EMC86185.1 - 1.5e-62 209.3 3.0 4.2e-23 81.7 0.1 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 EMC86185.1 - 1.1e-47 161.2 0.2 6.9e-17 61.6 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.1 EMC86185.1 - 1.1e-12 48.4 0.3 2.3e-05 24.6 0.1 3.3 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 EMC86185.1 - 1.9e-05 24.4 31.1 0.00038 20.3 5.9 3.7 3 0 0 3 3 3 2 EGF-like domain COLFI PF01410.13 EMC86185.1 - 3.9e-05 23.1 1.4 0.0022 17.4 0.5 3.0 2 1 0 2 2 2 1 Fibrillar collagen C-terminal domain PMP1_2 PF08114.6 EMC86185.1 - 2.8 7.5 5.9 5.6 6.5 4.1 1.4 1 0 0 1 1 1 0 ATPase proteolipid family F5_F8_type_C PF00754.20 EMC86186.1 - 3.1e-29 101.4 1.6 4.9e-29 100.7 0.2 1.9 2 0 0 2 2 2 1 F5/8 type C domain Laminin_G_2 PF02210.19 EMC86186.1 - 1.4e-26 93.0 0.6 2.6e-26 92.1 0.4 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 EMC86186.1 - 3.2e-15 56.2 0.1 5.6e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain SPRY PF00622.23 EMC86188.1 - 2e-18 66.6 0.0 3.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 EMC86188.1 - 6.2e-11 41.6 0.2 2.1e-10 39.9 0.0 2.1 2 0 0 2 2 1 1 SPRY-associated domain zf-B_box PF00643.19 EMC86188.1 - 3.8e-09 36.2 18.3 1.7e-08 34.1 0.6 5.2 6 1 0 6 6 5 2 B-box zinc finger fn3 PF00041.16 EMC86188.1 - 2.8e-08 33.7 0.2 6.4e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.1 EMC86188.1 - 9e-08 31.6 7.6 9e-08 31.6 5.2 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC86188.1 - 3.8e-07 30.0 11.6 3.8e-07 30.0 8.0 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC86188.1 - 2.4e-06 27.3 12.3 2.4e-06 27.3 8.5 5.2 5 1 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMC86188.1 - 3e-06 26.7 11.6 3e-06 26.7 8.1 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC86188.1 - 5.1e-06 26.2 11.8 5.1e-06 26.2 8.2 3.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EMC86188.1 - 0.00024 20.7 10.0 0.00024 20.7 7.0 4.5 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC86188.1 - 0.00032 20.3 7.2 0.00032 20.3 5.0 3.2 3 0 0 3 3 3 1 RING-type zinc-finger DNA_photolyase PF00875.13 EMC86188.1 - 0.18 11.5 1.9 0.23 11.1 0.3 1.9 2 0 0 2 2 2 0 DNA photolyase Baculo_PEP_C PF04513.7 EMC86188.1 - 0.31 10.8 6.2 0.082 12.7 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LcrG PF07216.7 EMC86188.1 - 0.81 9.7 4.0 2.4 8.2 1.0 2.4 2 0 0 2 2 2 0 LcrG protein DNA_topoisoIV PF00521.15 EMC86188.1 - 2.4 6.9 8.4 3.7 6.2 5.8 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF2370 PF10176.4 EMC86189.1 - 1.3e-43 148.9 19.3 2.1e-32 112.3 8.2 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) DUF202 PF02656.10 EMC86189.1 - 0.94 9.7 3.9 3.6 7.8 2.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) TMEM52 PF14979.1 EMC86189.1 - 1.1 9.1 10.4 0.09 12.6 1.5 2.4 2 1 0 2 2 2 0 Transmembrane 52 DUF3446 PF11928.3 EMC86189.1 - 3.9 7.7 10.9 8.3 6.6 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Sprouty PF05210.8 EMC86190.1 - 4.9e-37 126.2 34.6 8e-37 125.5 24.0 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) Yae1_N PF09811.4 EMC86191.1 - 4.7e-16 58.0 51.4 1.5e+04 -12.5 35.7 5.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-C3HC4_3 PF13920.1 EMC86193.1 - 9.8e-11 41.1 7.4 1.9e-10 40.2 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC86193.1 - 4.7e-09 35.9 10.3 1.1e-08 34.6 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC86193.1 - 7.8e-09 35.0 8.0 1.4e-08 34.2 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC86193.1 - 8.1e-08 32.1 9.9 1.5e-07 31.2 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC86193.1 - 1.7e-06 28.0 6.7 4.1e-06 26.8 4.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC86193.1 - 8.2e-06 25.4 7.4 1.7e-05 24.4 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC86193.1 - 0.0015 18.2 5.1 0.0074 16.0 3.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EMC86193.1 - 0.0027 17.3 3.3 0.0071 16.0 2.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC86193.1 - 0.0043 16.8 7.4 0.0096 15.7 5.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC86193.1 - 0.012 15.1 7.7 0.034 13.7 2.2 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EMC86193.1 - 0.33 10.6 2.5 0.57 9.8 1.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1644 PF07800.7 EMC86193.1 - 0.47 10.3 7.0 0.92 9.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) zf-MIZ PF02891.15 EMC86193.1 - 0.5 9.9 9.7 0.66 9.5 0.3 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-CCCH PF00642.19 EMC86194.1 - 0.0048 16.5 24.4 57 3.5 0.1 8.1 8 0 0 8 8 8 8 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Drf_FH1 PF06346.7 EMC86194.1 - 0.005 16.3 9.3 0.059 12.8 1.1 2.1 1 1 1 2 2 2 2 Formin Homology Region 1 RVT_1 PF00078.22 EMC86195.1 - 0.03 13.6 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1689 PF07954.6 EMC86196.1 - 0.1 12.4 8.1 61 3.4 1.2 5.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1689) 7tm_4 PF13853.1 EMC86198.1 - 3.6e-49 166.2 7.8 4.1e-49 166.0 5.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC86198.1 - 0.00012 21.2 5.4 0.00016 20.9 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1240 PF06836.7 EMC86198.1 - 0.12 12.6 2.3 0.17 12.1 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Baculo_11_kDa PF06143.6 EMC86198.1 - 0.13 11.6 0.8 0.2 11.0 0.5 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Microvir_lysis PF04517.7 EMC86199.1 - 0.018 14.7 0.6 0.042 13.5 0.4 1.6 1 0 0 1 1 1 0 Microvirus lysis protein (E), C terminus SID-1_RNA_chan PF13965.1 EMC86200.1 - 2e-232 772.4 18.4 2.3e-232 772.2 12.7 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 HLH PF00010.21 EMC86201.1 - 1.8e-11 43.5 0.6 6.2e-11 41.8 0.4 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhoU PF01895.14 EMC86201.1 - 0.52 10.7 0.8 1.2 9.6 0.6 1.6 1 0 0 1 1 1 0 PhoU domain Acetyltransf_1 PF00583.19 EMC86202.1 - 2.4e-16 59.5 0.0 3.4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC86202.1 - 3.6e-10 39.8 0.1 6.4e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC86202.1 - 2.5e-07 30.7 0.1 2.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC86202.1 - 3.2e-07 30.4 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMC86202.1 - 2.8e-06 27.2 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC86202.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC86202.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EMC86202.1 - 0.00071 19.7 0.0 0.00084 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Epsilon_antitox PF08998.6 EMC86202.1 - 0.016 15.1 0.1 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial epsilon antitoxin DUF3749 PF12568.3 EMC86202.1 - 0.058 12.9 0.0 0.074 12.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2206 PF09971.4 EMC86202.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) ATP-synt_ab PF00006.20 EMC86203.1 - 1.1e-111 371.5 0.0 1.6e-111 370.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC86203.1 - 2e-28 99.0 0.5 3.5e-28 98.3 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC86203.1 - 6.4e-14 51.9 2.1 1.7e-13 50.5 1.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EMC86203.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Yippee-Mis18 PF03226.9 EMC86204.1 - 0.041 13.9 2.1 0.12 12.3 0.7 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EMC86204.1 - 0.93 9.3 6.5 25 4.7 4.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF1693 PF07984.7 EMC86205.1 - 1.8e-170 566.1 1.2 2.1e-170 565.9 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) CRAL_TRIO_2 PF13716.1 EMC86206.1 - 5.3e-33 114.0 2.7 9.8e-33 113.1 1.9 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.16 EMC86206.1 - 3.9e-26 91.2 0.0 7e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.15 EMC86206.1 - 2.6e-06 26.9 1.3 6.6e-06 25.7 0.9 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain WD40 PF00400.27 EMC86207.1 - 1.1e-77 253.4 12.2 2.8e-10 39.6 0.0 10.5 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp12 PF04003.7 EMC86207.1 - 1.1e-25 89.6 0.2 1.1e-25 89.6 0.2 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EMC86207.1 - 0.015 14.0 0.5 3.2 6.4 0.0 3.9 2 2 0 5 5 5 0 Nup133 N terminal like Nup160 PF11715.3 EMC86207.1 - 0.64 8.0 7.7 5.2 5.0 0.1 4.4 3 3 0 4 4 4 0 Nucleoporin Nup120/160 PapD-like PF14874.1 EMC86208.1 - 3e-10 39.9 0.0 5.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like T-box PF00907.17 EMC86209.1 - 9.5e-72 240.3 0.1 1.3e-71 239.9 0.1 1.2 1 0 0 1 1 1 1 T-box T-box PF00907.17 EMC86210.1 - 4.3e-07 29.5 0.0 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 T-box tRNA-synt_1b PF00579.20 EMC86211.1 - 4.2e-68 229.6 0.0 5.5e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FMN_dh PF01070.13 EMC86212.1 - 1.9e-132 441.4 0.1 5e-132 440.0 0.1 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMC86212.1 - 4e-07 29.2 0.4 1.5e-06 27.3 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMC86212.1 - 6.1e-05 22.0 0.1 8.5e-05 21.6 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EMC86212.1 - 0.00071 18.9 0.2 0.004 16.4 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EMC86212.1 - 0.0086 15.1 0.3 0.29 10.1 0.1 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 EMC86212.1 - 0.057 12.5 2.1 0.09 11.9 1.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 EMC86212.1 - 0.069 12.0 0.2 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.12 EMC86212.1 - 0.11 11.5 0.2 2.6 7.1 0.0 2.5 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI 3Beta_HSD PF01073.14 EMC86213.1 - 7.1e-111 369.3 0.0 8.4e-111 369.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC86213.1 - 3.9e-21 75.5 0.0 5.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC86213.1 - 7.3e-18 64.3 0.0 1.4e-17 63.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMC86213.1 - 3.1e-11 42.7 0.0 4.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC86213.1 - 7.8e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC86213.1 - 1.1e-06 28.1 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EMC86213.1 - 5.5e-06 25.4 0.0 1.3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMC86213.1 - 1.3e-05 25.2 0.1 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC86213.1 - 0.0031 17.1 0.1 0.0069 16.0 0.1 1.5 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EMC86213.1 - 0.019 13.9 0.1 0.043 12.7 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF2895 PF11444.3 EMC86214.1 - 0.04 13.1 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Sex_peptide PF08138.6 EMC86214.1 - 0.043 13.6 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family Glyco_hydro_47 PF01532.15 EMC86215.1 - 4.9e-154 513.3 0.0 6.3e-154 512.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 OmpH PF03938.9 EMC86215.1 - 0.12 12.2 6.5 0.27 11.1 4.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP-synt_B PF00430.13 EMC86215.1 - 4.6 7.0 9.7 9.6 6.0 6.8 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) C2-set_2 PF08205.7 EMC86216.1 - 2.9e-06 27.1 0.1 5.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC86216.1 - 0.00018 21.3 2.1 0.0037 17.1 0.5 2.2 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 EMC86216.1 - 0.00041 20.1 0.1 0.0037 17.0 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain C1-set PF07654.10 EMC86216.1 - 0.0037 17.2 0.9 0.63 10.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_3 PF13927.1 EMC86216.1 - 0.016 15.7 0.6 0.065 13.7 0.2 2.3 2 1 0 2 2 2 0 Immunoglobulin domain V-set_CD47 PF08204.6 EMC86216.1 - 0.085 12.6 0.6 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain ANF_receptor PF01094.23 EMC86217.1 - 3.7e-107 358.1 0.0 4.6e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 EMC86217.1 - 3.3e-83 278.6 28.4 6e-83 277.8 19.7 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 EMC86217.1 - 2.7e-19 68.6 10.5 7.8e-19 67.1 7.3 1.9 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 EMC86217.1 - 2.9e-13 49.8 0.0 5.4e-12 45.7 0.0 2.5 2 1 0 2 2 2 1 Periplasmic binding protein GCC2_GCC3 PF07699.8 EMC86217.1 - 0.0081 15.7 4.9 0.017 14.7 2.7 2.0 1 1 0 1 1 1 1 GCC2 and GCC3 PIG-P PF08510.7 EMC86217.1 - 1.6 8.3 6.6 0.72 9.4 1.0 2.7 2 0 0 2 2 2 0 PIG-P Cystatin PF00031.16 EMC86218.1 - 2.3e-14 53.2 0.3 2.5e-14 53.1 0.2 1.0 1 0 0 1 1 1 1 Cystatin domain Dynein_light PF01221.13 EMC86218.1 - 0.076 13.0 0.4 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Dynein light chain type 1 Cystatin PF00031.16 EMC86219.1 - 1.4e-16 60.3 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain DUF3828 PF12883.2 EMC86219.1 - 0.027 14.3 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Orbi_VP3 PF01700.11 EMC86219.1 - 0.067 10.6 0.1 0.08 10.3 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Cid2 PF09774.4 EMC86220.1 - 1.7e-32 112.5 6.3 2.6e-32 111.9 4.4 1.3 1 1 0 1 1 1 1 Caffeine-induced death protein 2 GAS PF13851.1 EMC86220.1 - 0.00083 18.6 2.9 0.001 18.2 2.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF837 PF05769.6 EMC86220.1 - 0.025 14.1 3.3 0.041 13.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) TACC PF05010.9 EMC86220.1 - 0.057 13.1 6.9 0.1 12.3 4.9 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Mnd1 PF03962.10 EMC86220.1 - 0.12 12.0 5.3 0.17 11.5 3.7 1.2 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EMC86220.1 - 0.17 11.4 3.3 0.29 10.7 2.3 1.3 1 0 0 1 1 1 0 IncA protein Pil1 PF13805.1 EMC86220.1 - 0.28 10.2 3.6 0.27 10.3 1.8 1.4 1 1 1 2 2 2 0 Eisosome component PIL1 DUF1075 PF06388.6 EMC86221.1 - 3.7e-45 153.1 0.1 4.3e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Arm PF00514.18 EMC86222.1 - 3.1e-86 280.5 15.5 1.3e-13 50.2 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC86222.1 - 6.3e-27 93.6 4.3 2.9e-08 33.8 0.0 5.6 2 1 6 8 8 7 7 HEAT repeats IBB PF01749.15 EMC86222.1 - 8.6e-27 93.1 8.0 1.8e-26 92.1 5.5 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EMC86222.1 - 3.5e-16 59.1 4.9 2.5e-05 24.5 0.0 5.8 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EMC86222.1 - 1.1e-10 40.6 9.8 0.00071 19.4 0.0 7.3 10 0 0 10 10 9 3 HEAT repeat RICTOR_V PF14668.1 EMC86222.1 - 1.8e-05 24.5 4.8 0.36 10.7 0.0 5.1 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 EMC86222.1 - 2.1e-05 23.7 0.6 0.2 10.7 0.2 3.2 2 2 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.3 EMC86222.1 - 0.00014 21.7 0.3 0.18 11.7 0.0 4.3 2 1 3 5 5 5 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 EMC86222.1 - 0.0078 14.5 1.5 0.021 13.0 0.2 2.0 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit TFCD_C PF12612.3 EMC86222.1 - 0.052 12.9 0.1 0.45 9.9 0.0 2.4 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal HEAT_PBS PF03130.11 EMC86222.1 - 1.8 9.2 7.9 8.7 7.1 0.2 5.0 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat V-set PF07686.12 EMC86223.1 - 3e-19 68.9 0.5 1.6e-12 47.3 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin V-set domain C1-set PF07654.10 EMC86223.1 - 5.8e-15 55.0 0.2 2.7e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.1 EMC86223.1 - 1.1e-13 51.4 9.1 9.3e-09 35.6 0.6 4.2 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 EMC86223.1 - 2e-13 50.0 0.0 1.2e-05 25.0 0.0 3.6 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC86223.1 - 3.9e-12 46.1 0.0 0.00011 22.2 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC86223.1 - 2.1e-06 27.7 4.9 0.0001 22.3 0.0 3.2 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC86223.1 - 0.002 18.0 0.6 0.0094 15.8 0.1 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 EMC86223.1 - 0.15 11.8 0.0 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain ASC PF00858.19 EMC86224.1 - 4.2e-110 368.3 10.8 5.2e-110 368.1 7.5 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Synaptobrevin PF00957.16 EMC86225.1 - 2.2e-34 116.9 2.7 2.4e-34 116.7 1.9 1.0 1 0 0 1 1 1 1 Synaptobrevin Med17 PF10156.4 EMC86225.1 - 0.014 13.6 0.1 0.018 13.3 0.0 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Tweety PF04906.8 EMC86225.1 - 0.079 11.3 0.3 0.099 11.0 0.2 1.0 1 0 0 1 1 1 0 Tweety HemX PF04375.9 EMC86225.1 - 0.27 9.8 3.8 0.32 9.5 2.6 1.0 1 0 0 1 1 1 0 HemX MRP-L51 PF10244.4 EMC86226.1 - 1.3e-41 140.5 1.5 1.6e-41 140.2 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit Gp_dh_C PF02800.15 EMC86227.1 - 1.8e-73 245.1 0.0 2.9e-73 244.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EMC86227.1 - 4.8e-56 188.9 0.1 9.2e-56 188.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA PF03968.9 EMC86227.1 - 0.043 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 OstA-like protein Filament PF00038.16 EMC86228.1 - 1.5e-13 50.9 26.8 5.4e-10 39.2 3.4 2.7 2 1 0 2 2 2 2 Intermediate filament protein Snapin_Pallidin PF14712.1 EMC86228.1 - 0.0084 16.4 2.1 0.0084 16.4 1.5 2.6 3 0 0 3 3 3 1 Snapin/Pallidin PAPA-1 PF04795.7 EMC86228.1 - 0.075 13.7 0.1 0.075 13.7 0.0 3.7 3 2 2 5 5 5 0 PAPA-1-like conserved region DUF1943 PF09172.6 EMC86228.1 - 0.31 9.8 3.0 1.2 7.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DUF4097 PF13349.1 EMC86228.1 - 1.6 8.2 3.8 2.7 7.5 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4097) Sds3 PF08598.6 EMC86228.1 - 1.7 8.1 14.8 1 8.8 3.0 2.5 1 1 1 2 2 2 0 Sds3-like 7tm_1 PF00001.16 EMC86229.1 - 7.4e-51 172.7 22.2 8.6e-51 172.5 15.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3302 PF11742.3 EMC86229.1 - 0.12 12.2 0.2 0.12 12.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) GWT1 PF06423.7 EMC86229.1 - 2.5 8.1 8.8 5.5 7.0 0.0 3.5 2 1 1 3 3 3 0 GWT1 60KD_IMP PF02096.15 EMC86229.1 - 3.2 7.3 10.9 0.36 10.4 1.8 2.4 2 1 0 2 2 2 0 60Kd inner membrane protein wnt PF00110.14 EMC86230.1 - 1.1e-80 271.2 2.2 1.2e-80 271.0 1.5 1.0 1 0 0 1 1 1 1 wnt family PBP_sp32 PF07222.7 EMC86231.1 - 2.4e-38 131.6 4.3 1.4e-36 125.9 0.1 2.7 2 0 0 2 2 2 2 Proacrosin binding protein sp32 Kazal_2 PF07648.10 EMC86231.1 - 0.00039 20.2 0.8 0.00039 20.2 0.5 3.7 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC86231.1 - 7.6 6.6 10.7 8.2 6.5 0.3 3.0 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain ING PF12998.2 EMC86232.1 - 6e-28 97.1 0.5 6e-28 97.1 0.4 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMC86232.1 - 5.1e-10 38.9 7.8 9e-10 38.0 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EMC86232.1 - 0.018 15.2 0.5 0.04 14.0 0.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EMC86232.1 - 0.021 14.1 1.3 0.037 13.3 0.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EMC86232.1 - 0.039 13.9 5.2 0.067 13.1 3.6 1.4 1 0 0 1 1 1 0 RING-like domain HCMV_UL139 PF12507.3 EMC86232.1 - 0.08 13.1 1.0 0.19 11.8 0.7 1.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein ORF6C PF10552.4 EMC86232.1 - 0.87 9.3 6.9 3 7.5 1.3 2.2 2 0 0 2 2 2 0 ORF6C domain RNase_H2-Ydr279 PF09468.5 EMC86232.1 - 1.3 8.1 7.9 1.7 7.7 5.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LMBR1 PF04791.11 EMC86232.1 - 5.7 5.3 6.2 6.2 5.2 3.7 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF1192 PF06698.6 EMC86232.1 - 9.4 6.1 8.1 2.2 8.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) zf-H2C2_2 PF13465.1 EMC86233.1 - 3.5e-40 134.3 69.2 3.2e-06 27.1 0.1 9.7 10 0 0 10 10 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 EMC86233.1 - 4.5e-32 108.4 77.8 2e-05 24.6 2.2 9.6 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC86233.1 - 1.1e-20 72.3 72.8 0.0003 20.9 1.9 10.2 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC86233.1 - 1.7e-07 30.9 56.1 0.15 12.0 0.1 9.0 9 0 0 9 9 9 6 C2H2-type zinc finger zf-Di19 PF05605.7 EMC86233.1 - 2e-07 31.0 42.8 0.0042 17.1 4.7 4.8 4 0 0 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EMC86233.1 - 6.3e-05 22.5 26.6 0.0034 16.9 0.4 6.2 6 0 0 6 6 6 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EMC86233.1 - 0.0019 18.3 54.7 0.022 14.9 0.3 8.8 8 1 1 9 9 8 3 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EMC86233.1 - 0.042 13.8 16.6 12 6.0 0.1 6.1 5 1 0 5 5 5 0 zinc-finger DUF2688 PF10892.3 EMC86233.1 - 0.09 12.4 0.7 5.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) zf-FCS PF06467.9 EMC86233.1 - 1 9.0 28.1 16 5.2 0.1 7.2 6 1 1 7 7 7 0 MYM-type Zinc finger with FCS sequence motif zf-met PF12874.2 EMC86233.1 - 2 8.7 60.4 0.073 13.2 1.5 8.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type TerY-C PF15616.1 EMC86233.1 - 6.4 6.7 18.3 0.66 9.9 1.4 3.2 2 1 2 4 4 4 0 TerY-C metal binding domain zf-AN1 PF01428.11 EMC86233.1 - 8.4 6.3 27.0 29 4.6 0.1 7.0 7 1 0 7 7 7 0 AN1-like Zinc finger PCI PF01399.22 EMC86234.1 - 6.8e-12 45.6 0.2 5e-11 42.8 0.0 2.1 2 1 0 2 2 2 1 PCI domain Sipho_Gp157 PF05565.6 EMC86234.1 - 0.017 14.7 0.3 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Rtf2 PF04641.7 EMC86234.1 - 0.038 13.2 2.3 0.05 12.8 1.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Mlf1IP PF10248.4 EMC86235.1 - 3.1e-75 251.6 6.9 4e-75 251.2 4.8 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein FANCI_HD1 PF14679.1 EMC86236.1 - 4.1 7.1 6.9 0.95 9.2 0.9 2.4 3 0 0 3 3 3 0 FANCI helical domain 1 Ig_2 PF13895.1 EMC86238.1 - 9.4e-09 35.2 0.4 5.6e-06 26.3 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC86238.1 - 4e-06 26.5 0.0 0.00023 20.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.12 EMC86238.1 - 0.00032 20.5 0.1 0.015 15.1 0.0 2.7 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 EMC86238.1 - 0.0017 18.4 0.1 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC86238.1 - 0.0039 17.6 1.9 1.6 9.2 0.8 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set PF05790.10 EMC86238.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin C2-set domain 7tm_1 PF00001.16 EMC86239.1 - 1.5e-20 73.4 11.8 2.1e-20 72.9 8.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC86239.1 - 0.00015 20.9 3.1 0.00015 20.9 2.1 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2062 PF09835.4 EMC86239.1 - 0.024 14.2 0.6 0.024 14.2 0.4 2.9 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF1049 PF06305.6 EMC86239.1 - 0.043 13.2 6.1 0.12 11.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Ni_hydr_CYTB PF01292.15 EMC86239.1 - 0.12 11.7 8.5 0.84 8.9 4.1 2.6 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 Herpes_gE PF02480.11 EMC86239.1 - 1.1 7.4 6.0 5.2 5.2 0.2 2.9 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E 2OG-FeII_Oxy_3 PF13640.1 EMC86240.1 - 1.6e-15 57.3 0.0 3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMC86240.1 - 0.00016 21.8 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMC86240.1 - 0.0022 17.5 0.1 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EMC86241.1 - 2.2e-54 179.5 26.7 8.3e-10 38.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC86241.1 - 8.6e-08 32.1 0.0 0.006 16.3 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMC86241.1 - 0.0056 15.0 0.0 0.065 11.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain UL11 PF11094.3 EMC86241.1 - 0.016 14.9 0.4 0.049 13.4 0.3 1.8 1 0 0 1 1 1 0 Membrane-associated tegument protein Pox_A_type_inc PF04508.7 EMC86241.1 - 0.047 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TIM PF00121.13 EMC86243.1 - 3.2e-79 265.4 0.1 3.8e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LRR_4 PF12799.2 EMC86244.1 - 1.3e-25 88.5 26.5 3.4e-08 32.9 0.6 5.7 1 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC86244.1 - 1.1e-23 82.7 50.3 2.8e-09 36.6 2.5 4.9 1 1 7 8 8 8 8 Leucine rich repeat LRR_9 PF14580.1 EMC86244.1 - 4.8e-15 55.5 4.8 4.4e-14 52.4 0.9 2.5 1 1 2 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.28 EMC86244.1 - 3e-12 44.7 20.3 0.079 13.0 0.2 8.3 6 3 1 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 EMC86244.1 - 1.9e-05 24.2 26.3 0.66 10.2 0.7 8.4 6 2 4 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 EMC86244.1 - 7e-05 22.4 28.6 3.5 8.2 0.2 9.2 10 1 0 10 10 10 2 Leucine rich repeat LRR_3 PF07725.7 EMC86244.1 - 0.16 11.8 11.2 5 7.0 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Enolase_C PF00113.17 EMC86245.1 - 2e-160 532.6 0.0 2.5e-160 532.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EMC86245.1 - 4.6e-58 194.8 0.0 7.4e-58 194.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EMC86245.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EMC86245.1 - 3.4e-05 22.8 0.3 7.5e-05 21.7 0.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EMC86245.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF4511 PF14974.1 EMC86246.1 - 1.3e-38 130.9 0.1 1.5e-38 130.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4511) FAST_2 PF08368.7 EMC86246.1 - 0.052 13.9 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 DUF4309 PF14172.1 EMC86246.1 - 0.062 13.2 0.0 1.1 9.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4309) Y_phosphatase PF00102.22 EMC86247.1 - 8e-80 267.5 0.2 1.3e-79 266.9 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.19 EMC86247.1 - 5.9e-45 150.9 0.0 3.3e-21 74.8 0.0 2.9 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.15 EMC86247.1 - 9.2e-06 25.2 0.1 2.7e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC86247.1 - 0.0036 17.3 1.0 0.0074 16.3 0.0 2.2 3 1 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC86247.1 - 0.0041 17.3 0.6 0.031 14.5 0.0 2.7 4 0 0 4 4 4 1 Tyrosine phosphatase family Band_7 PF01145.20 EMC86248.1 - 3.3e-17 62.9 5.1 4.7e-17 62.4 3.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 EMC86248.1 - 0.001 19.0 2.0 0.0019 18.1 1.4 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF1481 PF07356.7 EMC86248.1 - 0.0012 18.3 1.1 0.002 17.6 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1481) ATP-synt_E PF05680.7 EMC86248.1 - 1.2 9.1 5.4 2.6 8.0 3.8 1.5 1 0 0 1 1 1 0 ATP synthase E chain MBOAT PF03062.14 EMC86249.1 - 1.9e-52 178.3 9.1 1.9e-52 178.3 6.3 2.5 2 1 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family Trypsin PF00089.21 EMC86250.1 - 4.7e-49 166.9 0.0 6.8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 EMC86250.1 - 4.8e-44 148.9 0.2 2.4e-23 82.2 0.0 2.4 2 0 0 2 2 2 2 CUB domain Sushi PF00084.15 EMC86250.1 - 2e-12 47.2 11.3 3.7e-08 33.5 0.4 3.5 3 1 0 3 3 3 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 EMC86250.1 - 4.4e-09 36.3 7.0 2e-08 34.1 4.8 2.3 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site CUB_2 PF02408.15 EMC86250.1 - 5.6e-05 22.6 0.9 0.35 10.4 0.0 2.6 2 0 0 2 2 2 2 CUB-like domain EGF_CA PF07645.10 EMC86250.1 - 9.2e-05 22.3 8.8 9.2e-05 22.3 6.1 3.0 3 0 0 3 3 3 1 Calcium-binding EGF domain EGF PF00008.22 EMC86250.1 - 0.001 18.9 8.6 0.001 18.9 6.0 2.5 2 0 0 2 2 2 1 EGF-like domain Trypsin_2 PF13365.1 EMC86250.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EMC86251.1 - 5.8e-51 173.1 0.0 8.6e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 EMC86251.1 - 6.1e-51 171.1 0.1 1.6e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 CUB domain Sushi PF00084.15 EMC86251.1 - 1.3e-15 57.4 17.1 2.8e-10 40.3 0.8 3.8 3 0 0 3 3 3 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 EMC86251.1 - 9.9e-09 35.1 10.6 4.2e-08 33.1 5.4 2.9 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC86251.1 - 3.1e-05 23.5 5.0 0.0002 20.9 1.3 3.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.10 EMC86251.1 - 7.9e-05 22.5 8.7 0.00013 21.8 4.8 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.22 EMC86251.1 - 0.00091 19.1 5.2 0.0044 16.9 3.6 2.3 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.15 EMC86251.1 - 0.0022 17.5 0.2 2.8 7.4 0.0 2.9 3 0 0 3 3 3 2 CUB-like domain Peptidase_S6 PF02395.11 EMC86251.1 - 0.017 13.3 0.1 0.024 12.7 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease Trypsin_2 PF13365.1 EMC86251.1 - 0.082 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Trypsin-like peptidase domain Lipocalin_7 PF14651.1 EMC86252.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Cadherin PF00028.12 EMC86253.1 - 4.4e-12 46.0 0.0 8.4e-06 25.9 0.0 2.7 3 0 0 3 3 3 2 Cadherin domain Laminin_G_3 PF13385.1 EMC86253.1 - 8.6e-08 32.5 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EMC86253.1 - 0.082 12.9 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Laminin G domain Mito_carr PF00153.22 EMC86254.1 - 1.8e-67 223.0 0.0 2.6e-22 78.3 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 EMC86255.1 - 1e-26 92.3 8.9 3.2e-13 49.1 0.1 4.6 3 2 2 6 6 5 4 TPR repeat TPR_1 PF00515.23 EMC86255.1 - 5.7e-25 85.8 1.1 3e-06 26.5 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMC86255.1 - 1.6e-20 71.2 5.3 0.00014 21.4 0.3 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86255.1 - 6.9e-17 60.1 1.4 0.0087 16.1 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC86255.1 - 3.8e-16 58.1 14.5 0.0081 16.7 0.2 7.8 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86255.1 - 3.4e-15 56.2 9.8 6.7e-07 29.8 0.5 5.4 4 2 2 6 6 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86255.1 - 1.2e-12 47.6 3.5 1.3e-06 28.2 0.9 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC86255.1 - 4.1e-11 41.8 1.0 0.33 10.8 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC86255.1 - 8.6e-11 40.7 0.4 0.13 12.1 0.0 5.9 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86255.1 - 3.5e-10 40.0 3.5 0.015 15.6 0.0 4.7 2 2 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC86255.1 - 4.9e-08 33.0 0.9 0.0015 18.6 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EMC86255.1 - 1e-07 31.9 0.1 0.26 11.4 0.0 4.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC86255.1 - 9.7e-07 28.5 2.5 0.23 11.4 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC86255.1 - 1.2e-06 28.3 6.6 0.042 13.7 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC86255.1 - 0.0009 19.5 8.7 3.7 8.2 0.1 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.1 EMC86255.1 - 0.0042 16.8 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain DUF1641 PF07849.6 EMC86255.1 - 0.097 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Secretin_N_2 PF07655.8 EMC86255.1 - 0.16 12.3 0.1 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Fis1_TPR_C PF14853.1 EMC86255.1 - 0.41 10.5 1.9 37 4.2 0.0 3.9 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Crystall PF00030.14 EMC86256.1 - 6.5e-35 118.8 0.4 2.2e-20 72.2 0.0 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EMC86256.1 - 2.4e-09 36.8 1.0 5.3e-05 22.8 0.2 3.0 2 1 1 3 3 3 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.8 EMC86256.1 - 0.00032 21.0 0.5 0.21 11.9 0.0 2.2 1 1 1 2 2 2 2 Peptidase inhibitor family I36 Pkinase_Tyr PF07714.12 EMC86257.1 - 1.2e-96 322.7 0.0 1.9e-96 322.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC86257.1 - 1.8e-65 220.0 0.1 2.7e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC86257.1 - 3.8e-49 167.1 0.0 5.8e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC86257.1 - 1.8e-24 85.6 0.0 3.7e-12 46.2 0.0 2.7 3 0 0 3 3 2 2 Fibronectin type III domain SAM_1 PF00536.25 EMC86257.1 - 2.2e-22 78.9 0.0 4.8e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC86257.1 - 5.4e-18 64.5 0.0 1.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 EMC86257.1 - 1.4e-12 47.7 0.0 2.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain GCC2_GCC3 PF07699.8 EMC86257.1 - 2.6e-05 23.6 2.4 2.6e-05 23.6 1.7 3.4 2 1 1 3 3 3 1 GCC2 and GCC3 Tissue_fac PF01108.12 EMC86257.1 - 0.012 15.3 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 Tissue factor SusE PF14292.1 EMC86257.1 - 0.018 14.8 0.0 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 SusE outer membrane protein Kdo PF06293.9 EMC86257.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD3G PF07562.9 EMC86257.1 - 5 6.9 12.3 0.15 11.7 2.0 2.9 2 1 1 3 3 3 0 Nine Cysteines Domain of family 3 GPCR cEGF PF12662.2 EMC86257.1 - 5.6 6.6 13.7 0.5 10.0 0.8 3.7 3 1 0 3 3 3 0 Complement Clr-like EGF-like FAM131 PF15010.1 EMC86258.1 - 4.8e-119 397.4 17.7 1.1e-118 396.3 12.3 1.5 1 1 0 1 1 1 1 Putative cell signalling Peptidase_C14 PF00656.17 EMC86259.1 - 5.2e-38 131.1 0.9 1e-37 130.2 0.2 1.7 2 0 0 2 2 2 1 Caspase domain CARD PF00619.16 EMC86259.1 - 1.8e-19 69.3 0.6 4.8e-19 67.9 0.4 1.7 1 0 0 1 1 1 1 Caspase recruitment domain TMEM51 PF15345.1 EMC86260.1 - 0.44 10.2 2.4 0.33 10.6 1.2 1.3 1 1 0 1 1 1 0 Transmembrane protein 51 Rap_GAP PF02145.10 EMC86261.1 - 2.4e-63 212.9 0.0 3.6e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP GoLoco PF02188.12 EMC86261.1 - 0.0015 17.8 2.6 0.0029 16.8 1.8 1.6 1 0 0 1 1 1 1 GoLoco motif DSBA PF01323.15 EMC86262.1 - 2.6e-48 164.1 0.0 2.9e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Peptidase_M13_N PF05649.8 EMC86263.1 - 1.3e-82 277.8 0.0 1.7e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EMC86263.1 - 3.5e-43 147.1 0.1 7e-43 146.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 Ank_2 PF12796.2 EMC86264.1 - 6.6e-27 93.6 3.3 5.4e-15 55.4 0.9 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86264.1 - 2.7e-21 74.2 0.8 1.7e-05 24.4 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EMC86264.1 - 4.6e-21 74.3 2.9 1.8e-06 28.0 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC86264.1 - 5.8e-21 74.4 0.3 8.3e-06 26.1 0.0 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86264.1 - 4.5e-20 69.7 2.2 4.9e-05 23.1 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ion_trans PF00520.26 EMC86264.1 - 5.3e-12 45.4 23.3 5.3e-12 45.4 16.1 3.1 3 0 0 3 3 3 2 Ion transport protein OKR_DC_1 PF01276.15 EMC86264.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase_Tyr PF07714.12 EMC86266.1 - 3.9e-94 314.5 0.0 5.2e-94 314.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 EMC86266.1 - 8.1e-75 250.5 0.1 1.2e-74 249.9 0.1 1.2 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 EMC86266.1 - 1.5e-46 158.7 0.0 2.2e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 EMC86266.1 - 2.4e-25 88.4 0.0 5.8e-15 55.1 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain SAM_1 PF00536.25 EMC86266.1 - 1.5e-20 73.1 0.1 2.9e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC86266.1 - 1.7e-20 72.6 0.0 3.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 EMC86266.1 - 6.3e-20 71.3 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain GCC2_GCC3 PF07699.8 EMC86266.1 - 6.2e-06 25.6 0.4 6.2e-06 25.6 0.3 2.4 2 0 0 2 2 2 1 GCC2 and GCC3 Y_Y_Y PF07495.8 EMC86266.1 - 0.026 14.2 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Y_Y_Y domain cEGF PF12662.2 EMC86266.1 - 0.048 13.3 0.4 0.048 13.3 0.2 2.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like Interfer-bind PF09294.5 EMC86266.1 - 0.095 12.7 0.0 0.64 10.0 0.0 2.3 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Kdo PF06293.9 EMC86266.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GAS2 PF02187.12 EMC86267.1 - 0.078 12.7 0.1 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Carb_kinase PF01256.12 EMC86268.1 - 0.026 13.8 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate kinase C1-set PF07654.10 EMC86269.1 - 3.9e-16 58.8 0.0 5.1e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.1 EMC86269.1 - 0.041 14.3 0.1 0.063 13.7 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.20 EMC86269.1 - 0.073 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.1 EMC86269.1 - 0.074 13.1 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.7 EMC86269.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC86270.1 - 1.4e-11 44.2 0.8 1.5e-11 44.1 0.6 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC86270.1 - 0.0015 18.6 0.1 0.0019 18.3 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain SRP1_TIP1 PF00660.12 EMC86270.1 - 0.0074 16.0 0.1 0.009 15.8 0.1 1.3 1 0 0 1 1 1 1 Seripauperin and TIP1 family ig PF00047.20 EMC86270.1 - 0.013 15.6 0.5 0.26 11.4 0.3 2.2 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 EMC86270.1 - 0.015 15.1 0.2 0.017 14.9 0.2 1.3 1 1 0 1 1 1 0 Immunoglobulin I-set domain Trypsin PF00089.21 EMC86271.1 - 0.00021 20.9 0.0 0.00024 20.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin FGF PF00167.13 EMC86272.1 - 6.6e-34 116.3 1.1 7.6e-34 116.1 0.8 1.0 1 0 0 1 1 1 1 Fibroblast growth factor I-set PF07679.11 EMC86273.1 - 4.5e-11 42.4 0.1 6.6e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC86273.1 - 7.5e-11 42.0 0.0 4e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 EMC86273.1 - 6e-08 32.5 0.6 3.1e-06 27.0 0.0 2.7 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 EMC86273.1 - 5.9e-07 29.5 0.4 0.0012 18.9 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC86273.1 - 4.2e-05 23.9 0.1 0.29 11.6 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 EMC86273.1 - 0.00045 18.6 0.0 0.0014 16.9 0.0 1.7 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E HTH_5 PF01022.15 EMC86273.1 - 0.016 14.8 0.5 0.032 13.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Gag_p30 PF02093.11 EMC86274.1 - 3.7e-26 91.6 0.1 4e-26 91.5 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 EMC86274.1 - 0.011 15.2 0.2 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Med28 PF11594.3 EMC86274.1 - 0.044 14.0 1.7 1.3 9.2 0.1 2.1 1 1 1 2 2 2 0 Mediator complex subunit 28 DUF4315 PF14193.1 EMC86274.1 - 0.067 13.1 2.9 0.67 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) PARP PF00644.15 EMC86275.1 - 4.5e-14 52.3 0.5 1.1e-13 51.0 0.4 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Yae1_N PF09811.4 EMC86276.1 - 1e-19 69.7 62.2 1.5e+04 -22.9 43.1 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal eRF1_1 PF03463.10 EMC86278.1 - 2.5e-49 166.2 0.1 4.4e-49 165.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EMC86278.1 - 5.2e-36 123.9 0.0 8.4e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMC86278.1 - 2.7e-26 92.0 0.1 7.6e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 MethyTransf_Reg PF10119.4 EMC86278.1 - 0.0082 16.6 0.0 0.051 14.0 0.0 2.3 1 1 1 2 2 2 1 Predicted methyltransferase regulatory domain Integrin_alpha2 PF08441.7 EMC86279.1 - 2e-71 241.2 10.1 3.1e-71 240.5 7.0 1.3 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.23 EMC86279.1 - 2.3e-41 141.4 0.5 4.7e-41 140.4 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.18 EMC86279.1 - 6e-14 51.2 11.3 3.4e-06 26.5 0.6 3.7 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.1 EMC86279.1 - 2.6e-11 43.9 0.1 4.8e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.1 EMC86279.1 - 2.9e-07 30.7 2.7 0.00017 21.8 1.3 3.6 3 1 1 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 EMC86279.1 - 3.3e-05 23.7 1.7 0.27 11.2 0.1 4.5 4 0 0 4 4 4 1 FG-GAP repeat Ferritin PF00210.19 EMC86279.1 - 0.036 13.8 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain Integrin_alpha PF00357.15 EMC86279.1 - 0.06 13.1 4.0 0.14 12.0 2.8 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region MoaE PF02391.12 EMC86280.1 - 2.8e-38 130.2 0.2 3.3e-38 130.0 0.2 1.1 1 0 0 1 1 1 1 MoaE protein Kazal_2 PF07648.10 EMC86281.1 - 1.6e-34 117.5 31.8 1.3e-13 50.6 1.1 5.0 4 1 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC86281.1 - 6.5e-25 86.8 39.2 8.9e-10 38.4 5.3 4.1 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain FOLN PF09289.5 EMC86281.1 - 1.3e-08 34.4 15.2 1.3e-08 34.4 10.5 4.7 4 1 0 4 4 4 2 Follistatin/Osteonectin-like EGF domain ETC_C1_NDUFA4 PF04800.7 EMC86282.1 - 6.3e-45 151.1 2.8 8.8e-45 150.7 2.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.4 EMC86282.1 - 0.016 15.0 0.1 0.046 13.6 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Arf PF00025.16 EMC86283.1 - 1.1e-29 102.8 0.0 1.3e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMC86283.1 - 3.8e-08 33.8 0.0 5e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EMC86283.1 - 7.7e-07 28.4 0.0 1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMC86283.1 - 8.2e-07 28.5 0.0 1e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC86283.1 - 2.4e-05 23.5 0.0 2.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC86283.1 - 4.1e-05 23.5 0.0 9.5e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EMC86283.1 - 0.0016 17.1 0.9 0.025 13.2 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit AAA PF00004.24 EMC86283.1 - 0.002 18.3 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC86283.1 - 0.0021 18.1 0.0 0.0032 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC86283.1 - 0.011 15.6 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EMC86283.1 - 0.014 14.7 0.1 0.12 11.8 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EMC86283.1 - 0.015 15.5 0.2 0.15 12.3 0.2 2.0 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 EMC86283.1 - 0.015 14.9 0.1 0.2 11.3 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EMC86283.1 - 0.02 14.8 0.2 0.044 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EMC86283.1 - 0.032 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EMC86283.1 - 0.034 13.6 0.1 1.8 8.0 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EMC86283.1 - 0.056 14.2 0.0 0.062 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC86283.1 - 0.056 13.6 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 RNA helicase PduV-EutP PF10662.4 EMC86283.1 - 0.068 12.6 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HSP20 PF00011.16 EMC86284.1 - 2.1e-15 56.4 0.0 2.9e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BAR_3_WASP_bdg PF10456.4 EMC86285.1 - 1.1e-114 381.6 7.0 1.3e-114 381.3 4.8 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 EMC86285.1 - 8.1e-22 77.1 0.4 2.2e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EMC86285.1 - 0.0061 15.8 3.9 0.0061 15.8 2.7 2.3 1 1 0 2 2 2 1 Vps5 C terminal like BAR PF03114.13 EMC86285.1 - 0.35 10.3 6.7 0.18 11.2 2.7 1.8 2 0 0 2 2 2 0 BAR domain IGFBP PF00219.13 EMC86286.1 - 2.6e-05 24.6 21.2 2.6e-05 24.6 14.7 2.4 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Trypsin PF00089.21 EMC86287.1 - 4.9e-69 232.2 1.6 5.5e-69 232.0 1.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC86287.1 - 0.0001 21.6 0.2 0.00014 21.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC86287.1 - 0.0009 19.2 0.3 0.002 18.1 0.2 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Redoxin PF08534.5 EMC86287.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Redoxin WD40 PF00400.27 EMC86288.1 - 9.1e-08 31.7 0.6 0.00019 21.1 0.0 3.3 2 1 1 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 EMC86288.1 - 0.077 11.1 0.0 0.1 10.6 0.0 1.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMC86288.1 - 0.13 11.0 0.1 1.9 7.1 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like GSHPx PF00255.14 EMC86289.1 - 2.2e-35 120.3 0.0 2.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EMC86289.1 - 1.7e-06 27.7 0.0 2.9e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.9 EMC86289.1 - 0.066 12.8 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 SCO1/SenC ABC2_membrane_6 PF06182.6 EMC86289.1 - 0.11 12.0 0.6 0.16 11.4 0.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein HA2 PF04408.18 EMC86290.1 - 7.2e-18 64.4 0.1 7.2e-18 64.4 0.1 2.6 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMC86290.1 - 8.9e-15 54.5 0.0 1e-13 51.0 0.0 2.7 2 1 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMC86290.1 - 3.6e-11 42.7 0.1 8.7e-11 41.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC86290.1 - 2.1e-09 37.0 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMC86290.1 - 1.3e-05 25.3 1.9 1.4e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EMC86290.1 - 0.0043 15.9 0.0 0.0088 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EMC86290.1 - 0.011 16.0 1.6 0.72 10.1 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EMC86290.1 - 0.021 14.8 1.8 1.2 9.1 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 EMC86290.1 - 0.049 13.1 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMC86290.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Bestrophin PF01062.16 EMC86290.1 - 1.4 7.8 5.2 0.14 11.0 0.1 1.9 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel PAP2 PF01569.16 EMC86291.1 - 7.1e-22 77.4 2.7 7.3e-22 77.4 1.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EMC86291.1 - 0.0051 17.0 2.9 0.0051 17.0 2.0 2.2 2 1 1 3 3 3 1 PAP2 superfamily C-terminal LrgB PF04172.11 EMC86291.1 - 0.023 13.8 0.1 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 LrgB-like family MVP_shoulder PF11978.3 EMC86291.1 - 0.11 12.3 0.0 4.5 7.1 0.0 2.6 2 1 1 3 3 3 0 Shoulder domain Polysacc_synt_C PF14667.1 EMC86291.1 - 9 6.0 9.1 0.42 10.3 1.1 2.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DEAD PF00270.24 EMC86293.1 - 3.1e-46 156.9 0.0 2.2e-45 154.1 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC86293.1 - 7.6e-28 96.2 0.1 2.8e-27 94.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMC86293.1 - 7.5e-05 21.6 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMC86293.1 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EMC86293.1 - 0.019 13.3 0.0 0.04 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) PSP1 PF04468.7 EMC86294.1 - 0.036 14.0 0.3 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 PSP1 C-terminal conserved region fn3 PF00041.16 EMC86295.1 - 5.2e-25 87.3 4.2 7.4e-09 35.6 0.0 4.2 4 0 0 4 4 4 3 Fibronectin type III domain Big_5 PF13205.1 EMC86295.1 - 0.0077 16.8 0.2 0.0077 16.8 0.1 2.6 1 1 1 2 2 2 1 Bacterial Ig-like domain Interfer-bind PF09294.5 EMC86295.1 - 0.023 14.7 0.2 4.5 7.3 0.1 2.7 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Big_3_4 PF13754.1 EMC86295.1 - 0.033 14.5 0.5 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) T2SG PF08334.6 EMC86295.1 - 0.07 12.8 0.5 0.72 9.6 0.1 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G fn3 PF00041.16 EMC86296.1 - 3.1e-32 110.5 9.7 3.8e-09 36.5 0.3 5.8 5 0 0 5 5 5 4 Fibronectin type III domain Lep_receptor_Ig PF06328.6 EMC86296.1 - 4e-32 109.9 2.1 6.8e-32 109.1 0.3 2.2 2 0 0 2 2 2 1 Ig-like C2-type domain EpoR_lig-bind PF09067.5 EMC86296.1 - 7.2e-06 25.9 0.0 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 EMC86296.1 - 1e-05 25.6 1.7 4.9e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 EMC86296.1 - 4.8e-05 23.0 0.3 0.04 13.6 0.0 4.1 3 0 0 3 3 3 1 Tissue factor DUF3377 PF11857.3 EMC86296.1 - 0.015 14.9 0.4 0.038 13.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Sarcoglycan_2 PF05510.8 EMC86296.1 - 0.05 11.9 0.0 0.11 10.7 0.0 1.5 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Miff PF05644.6 EMC86296.1 - 0.15 11.6 0.6 0.26 10.8 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Acetyltransf_1 PF00583.19 EMC86300.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC86300.1 - 9.1e-10 38.5 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC86300.1 - 0.0003 20.7 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC86300.1 - 0.0063 16.6 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC86300.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PPR_3 PF13812.1 EMC86300.1 - 0.12 12.7 0.0 7.1 7.1 0.0 2.9 2 1 1 3 3 3 0 Pentatricopeptide repeat domain DSPc PF00782.15 EMC86301.1 - 2.2e-38 130.8 0.0 2.7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC86301.1 - 0.0087 15.4 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_33 PF13592.1 EMC86301.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix AAA PF00004.24 EMC86302.1 - 4.6e-44 149.8 0.0 8.3e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC86302.1 - 1.3e-07 31.8 0.1 0.00038 20.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EMC86302.1 - 2.6e-07 30.8 0.2 4.6e-06 26.7 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EMC86302.1 - 5e-06 26.5 0.0 5.9e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMC86302.1 - 7.2e-06 25.7 0.2 0.0002 21.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMC86302.1 - 1.6e-05 24.1 0.0 3.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMC86302.1 - 6.7e-05 23.7 0.0 0.00019 22.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC86302.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EMC86302.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC86302.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMC86302.1 - 0.0026 16.7 0.0 0.0091 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EMC86302.1 - 0.003 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EMC86302.1 - 0.0032 16.9 0.1 0.017 14.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC86302.1 - 0.0032 17.7 0.0 0.01 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EMC86302.1 - 0.0052 16.3 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMC86302.1 - 0.0069 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EMC86302.1 - 0.0087 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EMC86302.1 - 0.0093 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 EMC86302.1 - 0.017 14.5 0.1 0.81 9.0 0.0 2.4 2 1 0 2 2 2 0 Thymidylate kinase NACHT PF05729.7 EMC86302.1 - 0.023 14.3 0.0 0.12 11.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.1 EMC86302.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC86302.1 - 0.043 13.3 0.1 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMC86302.1 - 0.046 12.8 0.5 0.44 9.6 0.0 2.5 2 1 1 3 3 3 0 KaiC SKI PF01202.17 EMC86302.1 - 0.051 13.4 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase Med3 PF11593.3 EMC86302.1 - 0.057 12.6 0.1 0.077 12.2 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Arch_ATPase PF01637.13 EMC86302.1 - 0.072 12.7 0.0 0.34 10.5 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 EMC86302.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 EMC86302.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EMC86302.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ERO1 PF04137.10 EMC86303.1 - 2.7e-122 408.2 0.0 3.1e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF1084 PF06454.6 EMC86304.1 - 0.011 14.7 6.5 0.0061 15.6 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1084) Thioredoxin_6 PF13848.1 EMC86305.1 - 2.6e-24 86.0 0.0 3.6e-19 69.2 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 EMC86305.1 - 4.3e-12 45.6 0.0 2.4e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Ldl_recept_b PF00058.12 EMC86306.1 - 1.8e-34 117.7 0.6 5.9e-13 48.9 0.0 5.1 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B EGF_CA PF07645.10 EMC86306.1 - 1.9e-25 88.5 44.9 1.7e-10 40.7 2.9 5.0 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF_3 PF12947.2 EMC86306.1 - 7.4e-24 83.4 51.7 5.9e-10 38.9 6.3 4.8 4 0 0 4 4 4 4 EGF domain G2F PF07474.7 EMC86306.1 - 5.3e-20 71.6 0.1 8e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 G2F domain cEGF PF12662.2 EMC86306.1 - 8.9e-19 66.8 36.2 5e-05 22.8 2.7 5.2 4 0 0 4 4 4 4 Complement Clr-like EGF-like Thyroglobulin_1 PF00086.13 EMC86306.1 - 2.5e-15 55.5 3.6 2.5e-15 55.5 2.5 3.3 4 0 0 4 4 3 1 Thyroglobulin type-1 repeat EGF PF00008.22 EMC86306.1 - 5.8e-08 32.5 60.4 0.00015 21.6 7.5 5.6 6 0 0 6 6 4 4 EGF-like domain SGL PF08450.7 EMC86306.1 - 5.8e-05 22.5 0.0 0.0011 18.4 0.0 3.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region FXa_inhibition PF14670.1 EMC86306.1 - 7.8e-05 22.7 24.3 0.00057 19.9 4.6 5.1 5 0 0 5 5 4 3 Coagulation Factor Xa inhibitory site hEGF PF12661.2 EMC86306.1 - 0.00017 21.4 26.0 0.0067 16.4 1.6 5.6 5 0 0 5 5 5 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 EMC86306.1 - 0.022 14.5 37.1 0.061 13.1 0.5 4.6 4 0 0 4 4 4 0 MSP1 EGF domain 1 Arylesterase PF01731.15 EMC86306.1 - 0.05 13.5 0.0 26 4.8 0.0 3.1 4 0 0 4 4 4 0 Arylesterase RLL PF10036.4 EMC86307.1 - 1.2e-95 319.6 2.3 1.3e-95 319.5 1.6 1.0 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein Cactin_mid PF10312.4 EMC86307.1 - 0.038 13.2 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Conserved mid region of cactin G-gamma PF00631.17 EMC86308.1 - 2e-20 72.2 0.0 2.3e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 GGL domain Mab-21 PF03281.9 EMC86311.1 - 2.3e-12 46.6 1.3 1.8e-09 37.1 0.4 2.2 2 0 0 2 2 2 2 Mab-21 protein Proteasome PF00227.21 EMC86312.1 - 2.3e-54 183.5 0.1 3.7e-54 182.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC86312.1 - 1.1e-14 53.4 0.1 1.8e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-Tim10_DDP PF02953.10 EMC86313.1 - 1.1e-17 63.0 2.8 1.3e-17 62.7 2.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.4 EMC86313.1 - 0.017 14.9 1.0 0.025 14.3 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PROCN PF08083.6 EMC86313.1 - 0.036 12.5 0.1 0.04 12.3 0.1 1.0 1 0 0 1 1 1 0 PROCN (NUC071) domain Ion_trans_2 PF07885.11 EMC86314.1 - 2.5e-33 113.6 20.2 1.9e-18 65.9 0.2 3.1 3 1 0 3 3 3 2 Ion channel DUF1104 PF06518.6 EMC86314.1 - 0.0017 18.4 0.3 0.0028 17.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1104) RAMP4 PF06624.7 EMC86314.1 - 5.2 6.6 5.6 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Mab-21 PF03281.9 EMC86315.1 - 1.4e-14 53.9 3.6 2.4e-13 49.8 2.5 2.1 1 1 0 1 1 1 1 Mab-21 protein TMEM51 PF15345.1 EMC86315.1 - 0.004 16.9 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 CENP-B_dimeris PF09026.5 EMC86315.1 - 0.015 15.5 7.8 0.034 14.3 4.6 2.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 EMC86315.1 - 3.3 6.3 9.6 4.8 5.8 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mab-21 PF03281.9 EMC86316.1 - 1e-09 38.0 4.2 1.1e-08 34.5 2.9 2.0 1 1 0 1 1 1 1 Mab-21 protein Pro_racemase PF05544.6 EMC86318.1 - 7.8e-78 261.5 0.0 8.8e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Proline racemase DUF766 PF05571.7 EMC86319.1 - 9.9e-122 405.8 12.2 1.1e-121 405.6 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF766) Jnk-SapK_ap_N PF09744.4 EMC86321.1 - 0.00066 19.7 1.1 0.00066 19.7 0.7 2.2 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 DUF2884 PF11101.3 EMC86321.1 - 0.007 15.7 1.4 0.007 15.7 1.0 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF2884) ADIP PF11559.3 EMC86321.1 - 0.0082 16.0 11.6 0.091 12.6 3.3 2.1 1 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding IFT57 PF10498.4 EMC86321.1 - 0.0086 14.8 7.5 0.0094 14.7 5.2 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 YjcZ PF13990.1 EMC86321.1 - 0.0095 15.0 4.5 0.6 9.1 0.9 2.0 1 1 1 2 2 2 2 YjcZ-like protein DUF489 PF04356.7 EMC86321.1 - 0.014 14.9 1.4 0.021 14.4 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF489) MscS_porin PF12795.2 EMC86321.1 - 0.021 14.1 5.6 0.036 13.3 1.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 EMC86321.1 - 0.022 13.2 8.3 0.028 12.8 5.7 1.2 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 EMC86321.1 - 0.023 14.1 9.6 0.066 12.6 6.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein Vip3A_N PF12495.3 EMC86321.1 - 0.039 13.6 1.6 0.052 13.2 0.9 1.4 1 1 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Mnd1 PF03962.10 EMC86321.1 - 0.041 13.5 9.4 0.2 11.3 4.3 2.1 1 1 1 2 2 2 0 Mnd1 family NEP PF10167.4 EMC86321.1 - 0.044 13.4 1.8 0.074 12.7 0.3 1.9 1 1 0 2 2 2 0 Uncharacterised conserved protein Syntaxin_2 PF14523.1 EMC86321.1 - 0.047 13.7 6.4 1.2 9.2 1.2 2.3 1 1 2 3 3 3 0 Syntaxin-like protein DUF2422 PF10337.4 EMC86321.1 - 0.067 11.9 1.4 0.086 11.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) COG2 PF06148.6 EMC86321.1 - 0.07 13.0 7.8 0.11 12.3 1.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF730 PF05325.6 EMC86321.1 - 0.07 12.9 4.0 0.16 11.8 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Baculo_PEP_C PF04513.7 EMC86321.1 - 0.084 12.6 4.8 1.5 8.6 1.5 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EMC86321.1 - 0.086 12.4 13.6 1 8.8 9.3 2.0 1 1 0 1 1 1 0 IncA protein Nsp1_C PF05064.8 EMC86321.1 - 0.11 12.1 8.4 0.3 10.7 1.5 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Nbl1_Borealin_N PF10444.4 EMC86321.1 - 0.12 11.7 1.1 8.9 5.7 0.1 2.6 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Prefoldin PF02996.12 EMC86321.1 - 0.13 11.9 15.8 0.11 12.2 1.4 3.8 1 1 3 4 4 4 0 Prefoldin subunit DUF4200 PF13863.1 EMC86321.1 - 0.16 11.9 12.9 0.14 12.1 0.8 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 EMC86321.1 - 0.16 11.9 12.3 0.17 11.8 1.7 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 EMC86321.1 - 0.18 11.5 11.2 2.4 7.9 2.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 EMC86321.1 - 0.19 11.4 15.0 2.2 8.0 0.9 3.2 2 1 1 3 3 3 0 Prefoldin subunit DUF3166 PF11365.3 EMC86321.1 - 0.19 12.1 3.9 0.36 11.2 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) FliD_C PF07195.7 EMC86321.1 - 0.2 10.9 3.1 6.6 5.9 0.1 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TPR_MLP1_2 PF07926.7 EMC86321.1 - 0.21 11.3 13.7 0.65 9.7 8.7 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EMC86321.1 - 0.21 10.7 11.0 3.3 6.8 7.7 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Methyltransf_28 PF02636.12 EMC86321.1 - 0.23 10.8 1.7 0.64 9.3 0.2 1.9 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Phage_GPO PF05929.6 EMC86321.1 - 0.24 10.6 5.6 0.46 9.7 1.0 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.7 EMC86321.1 - 0.27 10.9 6.8 1.6 8.4 0.5 2.2 1 1 1 2 2 2 0 Laminin Domain II Sipho_Gp157 PF05565.6 EMC86321.1 - 0.28 10.7 11.2 0.84 9.1 3.7 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 DUF4164 PF13747.1 EMC86321.1 - 0.34 11.0 5.5 8.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3347 PF11827.3 EMC86321.1 - 0.35 10.8 4.7 0.17 11.8 1.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) TMPIT PF07851.8 EMC86321.1 - 0.42 9.6 4.6 0.52 9.3 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein FliJ PF02050.11 EMC86321.1 - 0.44 10.6 7.4 0.84 9.6 1.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein FlxA PF14282.1 EMC86321.1 - 0.53 10.2 9.7 0.15 12.0 2.4 2.4 1 1 1 2 2 2 0 FlxA-like protein Matrilin_ccoil PF10393.4 EMC86321.1 - 0.54 9.6 8.0 0.42 10.0 0.2 2.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin CENP-H PF05837.7 EMC86321.1 - 0.63 10.2 9.6 0.61 10.2 1.9 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HR1 PF02185.11 EMC86321.1 - 0.75 9.5 10.0 2 8.2 0.1 3.6 2 1 1 3 3 3 0 Hr1 repeat GvpK PF05121.7 EMC86321.1 - 0.83 9.5 7.3 0.4 10.5 0.3 3.1 2 1 1 4 4 3 0 Gas vesicle protein K KfrA_N PF11740.3 EMC86321.1 - 0.93 9.9 8.5 17 5.8 3.0 2.7 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term WXG100 PF06013.7 EMC86321.1 - 0.95 9.5 3.6 34 4.5 1.5 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Helicase_IV_N PF12462.3 EMC86321.1 - 1 8.9 3.5 0.87 9.2 0.7 2.0 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF3450 PF11932.3 EMC86321.1 - 1.1 8.4 6.9 2.3 7.4 4.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.2 EMC86321.1 - 1.4 8.7 13.1 3.9 7.3 9.1 1.8 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.7 EMC86321.1 - 1.5 8.5 7.2 5.2 6.8 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EMC86321.1 - 1.8 7.1 13.5 1.8 7.1 3.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.8 EMC86321.1 - 1.8 8.3 8.5 7.6 6.3 0.4 2.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF607 PF04678.8 EMC86321.1 - 1.9 8.3 6.8 3.3 7.5 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF972 PF06156.8 EMC86321.1 - 1.9 8.8 8.5 2.7 8.3 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ACCA PF03255.9 EMC86321.1 - 1.9 8.0 7.3 3.4 7.1 0.5 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1843 PF08898.5 EMC86321.1 - 2.2 8.3 10.7 0.26 11.3 2.2 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF1843) Syntaxin PF00804.20 EMC86321.1 - 2.5 8.3 11.7 9.2 6.4 3.6 2.8 1 1 1 2 2 2 0 Syntaxin XhlA PF10779.4 EMC86321.1 - 2.6 8.0 10.3 0.33 10.8 0.9 2.4 1 1 1 2 2 2 0 Haemolysin XhlA DUF919 PF06034.6 EMC86321.1 - 2.8 7.6 5.8 1.6 8.3 0.6 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) APG6 PF04111.7 EMC86321.1 - 3.3 6.6 12.7 2.6 6.9 6.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Rootletin PF15035.1 EMC86321.1 - 3.5 7.5 9.3 50 3.8 6.4 2.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ING PF12998.2 EMC86321.1 - 3.7 7.8 9.9 6.9 7.0 3.2 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF848 PF05852.6 EMC86321.1 - 4.1 7.2 9.5 5.7 6.7 2.7 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SlyX PF04102.7 EMC86321.1 - 4.8 7.6 6.6 12 6.3 2.0 2.6 2 1 0 2 2 2 0 SlyX DUF2762 PF10960.3 EMC86321.1 - 4.9 6.9 7.4 8.7 6.1 0.1 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2762) IATP PF04568.7 EMC86321.1 - 5.4 7.1 9.8 8.7 6.4 0.2 2.9 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF4140 PF13600.1 EMC86321.1 - 5.5 7.4 9.5 1.7 9.1 0.9 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) AAA_23 PF13476.1 EMC86321.1 - 5.6 7.2 15.3 1.2e+02 2.8 10.6 2.0 1 1 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.1 EMC86321.1 - 8.2 5.5 13.0 4.5 6.3 4.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Acyl-CoA_dh_C PF12806.2 EMC86321.1 - 9.3 6.1 6.7 33 4.3 0.9 2.9 2 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like DUF724 PF05266.9 EMC86321.1 - 9.9 5.7 11.6 1.8 8.1 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Pecanex_C PF05041.10 EMC86322.1 - 1.4e-50 171.5 0.0 2.2e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) adh_short PF00106.20 EMC86323.1 - 3.3e-26 92.1 0.0 5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC86323.1 - 8.6e-11 42.0 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC86323.1 - 5.9e-10 39.0 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 KR domain PP2C PF00481.16 EMC86324.1 - 1.6e-87 293.1 0.0 2e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 EMC86324.1 - 6.3e-36 122.3 0.1 1.3e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.1 EMC86324.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Homeobox PF00046.24 EMC86326.1 - 6e-13 48.2 3.5 1e-12 47.4 0.8 2.2 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EMC86326.1 - 1.9e-09 37.0 0.4 4.2e-09 35.9 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.17 EMC86326.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.3 EMC86326.1 - 0.026 13.5 0.0 0.054 12.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.1 EMC86326.1 - 0.047 13.3 0.1 0.39 10.4 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 EMC86326.1 - 0.052 13.5 0.3 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain TniQ PF06527.6 EMC86326.1 - 0.063 13.4 0.6 0.12 12.5 0.3 1.6 1 1 0 1 1 1 0 TniQ Apc3 PF12895.2 EMC86326.1 - 0.095 12.8 0.5 0.17 12.0 0.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CENP-B_N PF04218.8 EMC86326.1 - 0.1 12.0 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Homeobox PF00046.24 EMC86327.1 - 1.7e-08 33.9 2.2 3e-08 33.1 0.3 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EMC86327.1 - 2.8e-05 23.7 0.6 6.1e-05 22.6 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC86327.1 - 0.0029 16.6 0.2 0.0074 15.3 0.1 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 EMC86327.1 - 0.0059 16.4 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix Homeobox PF00046.24 EMC86328.1 - 1.3e-13 50.3 1.0 2.6e-13 49.3 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC86328.1 - 1.1e-07 31.4 0.5 2.8e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EMC86328.1 - 0.033 13.2 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MAT1 PF06391.8 EMC86329.1 - 3.8e-83 277.9 20.8 4.4e-83 277.7 14.4 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 FRG PF08867.6 EMC86329.1 - 0.62 10.6 4.3 1.3 9.5 2.9 1.8 1 1 0 1 1 1 0 FRG domain AAA_23 PF13476.1 EMC86329.1 - 1.9 8.7 15.9 3 8.1 11.0 1.2 1 0 0 1 1 1 0 AAA domain Activator_LAG-3 PF11498.3 EMC86329.1 - 4 6.0 10.0 5.5 5.6 6.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Met_10 PF02475.11 EMC86330.1 - 3.1e-68 229.3 0.0 4.8e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.5 EMC86330.1 - 4.8e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EMC86330.1 - 0.00071 20.1 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC86330.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 EMC86330.1 - 0.0013 17.7 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.10 EMC86330.1 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase tRNA_U5-meth_tr PF05958.6 EMC86330.1 - 0.023 13.4 0.0 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.8 EMC86330.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aa_trans PF01490.13 EMC86331.1 - 7e-74 248.7 38.2 8.3e-74 248.4 26.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_US9 PF06072.6 EMC86331.1 - 1.6 8.6 0.0 1.6 8.6 0.0 3.2 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 Pkinase PF00069.20 EMC86332.1 - 6.3e-65 218.9 0.0 1.1e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86332.1 - 2.4e-36 125.1 0.0 3.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EMC86332.1 - 8.1e-30 102.3 30.8 4.2e-15 55.1 4.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.25 EMC86332.1 - 3.7e-11 42.6 0.1 7.7e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.19 EMC86332.1 - 2.9e-09 37.3 0.2 5e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC86332.1 - 5.6e-06 25.5 0.0 5.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC86332.1 - 0.081 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC86332.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DZR PF12773.2 EMC86332.1 - 1.1 9.0 13.5 0.05 13.4 1.4 2.8 2 0 0 2 2 2 0 Double zinc ribbon PAS_11 PF14598.1 EMC86333.1 - 3.6e-27 94.5 0.7 1.7e-22 79.4 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EMC86333.1 - 1.9e-25 88.7 0.1 3.8e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold HIF-1a_CTAD PF08778.5 EMC86333.1 - 1.6e-22 78.6 0.6 3.3e-22 77.6 0.4 1.6 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.3 EMC86333.1 - 1.3e-16 59.4 7.0 2.9e-16 58.3 4.9 1.6 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 PAS PF00989.19 EMC86333.1 - 4.5e-16 58.6 0.0 1.2e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EMC86333.1 - 3.7e-12 46.5 0.0 1.9e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMC86333.1 - 2e-08 34.2 0.0 0.00093 19.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 EMC86333.1 - 0.0093 15.6 3.0 0.01 15.5 0.2 2.4 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain SNAPc_SNAP43 PF09808.4 EMC86334.1 - 1.4e-47 161.9 4.1 1.4e-47 161.9 2.8 1.5 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 GSH_synth_ATP PF03917.12 EMC86334.1 - 0.032 12.8 0.5 0.046 12.2 0.4 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain C2 PF00168.25 EMC86335.1 - 1.4e-16 60.1 0.0 4.1e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain SERTA PF06031.8 EMC86336.1 - 3e-14 51.9 1.6 4.5e-14 51.4 1.1 1.3 1 0 0 1 1 1 1 SERTA motif Ras PF00071.17 EMC86337.1 - 1e-48 164.8 0.0 1.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC86337.1 - 4.4e-17 62.6 0.0 6.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC86337.1 - 2e-05 23.9 0.0 2.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MobB PF03205.9 EMC86337.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cys_knot PF00007.17 EMC86339.1 - 4.3e-13 49.2 4.5 4.3e-13 49.2 3.1 1.0 1 0 0 1 1 1 1 Cystine-knot domain zf-C3HC4_4 PF15227.1 EMC86339.1 - 0.2 11.5 3.3 0.33 10.8 1.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING B56 PF01603.15 EMC86340.1 - 4.4e-179 595.3 11.1 5.1e-179 595.1 7.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4194 PF13835.1 EMC86340.1 - 0.085 12.2 1.3 3 7.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) Sec7_N PF12783.2 EMC86340.1 - 0.2 11.0 7.4 1.3 8.4 0.5 3.5 3 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal KNTase_C PF07827.6 EMC86341.1 - 0.044 13.5 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 KNTase C-terminal domain WD40 PF00400.27 EMC86342.1 - 3.7e-21 74.1 6.1 2.9e-05 23.7 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat PAP2 PF01569.16 EMC86343.1 - 2.9e-18 65.8 5.7 2.9e-18 65.8 3.9 1.8 2 0 0 2 2 2 1 PAP2 superfamily FTHFS PF01268.14 EMC86344.1 - 1.6e-259 861.5 0.1 2.1e-259 861.1 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EMC86344.1 - 1.9e-67 225.3 1.1 1.9e-67 225.3 0.8 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMC86344.1 - 3.7e-33 114.0 0.1 4.3e-32 110.5 0.2 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain BTB PF00651.26 EMC86346.1 - 1.2e-19 70.3 1.5 1.2e-19 70.3 1.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.1 EMC86346.1 - 5e-14 51.5 62.0 0.0015 18.7 0.1 10.6 10 1 0 10 10 10 7 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC86346.1 - 1.1e-10 41.2 62.3 0.012 15.8 0.2 10.5 8 1 1 9 9 9 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC86346.1 - 2e-07 30.9 51.9 0.00026 21.1 2.3 9.5 9 2 0 9 9 9 5 Zinc-finger double domain zf-met PF12874.2 EMC86346.1 - 0.0014 18.7 42.2 0.095 12.9 0.3 9.1 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC86346.1 - 0.0081 16.2 0.2 0.0081 16.2 0.2 8.7 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC86346.1 - 0.7 9.8 0.0 0.54 10.2 0.1 8.2 8 0 0 8 8 8 0 C2H2-type zinc finger zf-Di19 PF05605.7 EMC86346.1 - 7.1 6.8 47.7 0.14 12.2 2.0 7.4 4 2 5 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding HSP70 PF00012.15 EMC86347.1 - 2.1e-275 914.3 11.5 2.4e-275 914.1 8.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMC86347.1 - 2e-17 62.7 0.7 7.7e-16 57.5 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EMC86347.1 - 0.00023 20.9 1.0 0.11 12.3 0.0 3.6 2 2 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.11 EMC86347.1 - 0.00025 20.7 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EMC86347.1 - 0.0021 17.2 2.2 0.019 14.0 0.1 2.9 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 EMC86347.1 - 0.018 13.8 0.4 0.17 10.6 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain PPPI_inhib PF14895.1 EMC86348.1 - 2.1e-34 118.8 0.0 2.6e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor TFIIB PF00382.14 EMC86349.1 - 4.5e-33 112.8 0.0 1.1e-15 57.1 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EMC86349.1 - 2.1e-26 91.9 11.9 2.1e-26 91.9 8.3 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EMC86349.1 - 1.4e-08 34.3 0.3 0.00023 20.6 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain PHR PF08005.7 EMC86350.1 - 1.9e-46 157.9 0.9 3.4e-46 157.1 0.6 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 EMC86350.1 - 1.9e-24 85.7 0.1 1.9e-23 82.5 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EMC86350.1 - 6.2e-07 29.2 3.0 1.1e-06 28.4 0.7 2.4 2 1 0 2 2 2 1 BTB And C-terminal Kelch NUDIX PF00293.23 EMC86351.1 - 9.1e-20 70.6 0.1 1.2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain ESPR PF13018.1 EMC86351.1 - 0.018 14.6 0.8 0.038 13.6 0.3 1.7 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system EGF PF00008.22 EMC86352.1 - 3e-70 231.5 282.2 2.3e-08 33.8 5.4 18.9 19 0 0 19 19 19 14 EGF-like domain MNNL PF07657.8 EMC86352.1 - 7.2e-28 96.3 1.4 7.2e-28 96.3 1.0 5.2 6 0 0 6 6 6 1 N terminus of Notch ligand DSL PF01414.14 EMC86352.1 - 9.3e-27 92.8 6.4 9.3e-27 92.8 4.4 14.0 10 3 5 15 15 15 1 Delta serrate ligand hEGF PF12661.2 EMC86352.1 - 1.4e-16 59.3 171.1 0.0072 16.3 4.3 19.2 18 0 0 18 18 18 12 Human growth factor-like EGF EGF_2 PF07974.8 EMC86352.1 - 1.6e-15 56.9 325.6 0.0061 16.6 5.0 20.2 20 0 0 20 20 20 14 EGF-like domain EGF_CA PF07645.10 EMC86352.1 - 2.9e-05 23.9 24.4 0.00031 20.6 7.1 19.9 9 4 11 20 20 20 9 Calcium-binding EGF domain DUF2920 PF11144.3 EMC86352.1 - 0.037 13.0 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) HSA PF07529.8 EMC86352.1 - 0.21 11.4 1.0 0.58 9.9 0.7 1.7 1 0 0 1 1 1 0 HSA PepSY_TM_2 PF13703.1 EMC86352.1 - 0.23 11.6 0.1 0.59 10.3 0.0 1.6 2 0 0 2 2 2 0 PepSY-associated TM helix EspB PF05802.6 EMC86352.1 - 0.81 8.5 2.2 9.2 5.1 0.1 2.1 2 0 0 2 2 2 0 Enterobacterial EspB protein 7tm_1 PF00001.16 EMC86353.1 - 4.4e-42 143.9 22.7 4.4e-42 143.9 15.7 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 EMC86353.1 - 6.6e-05 21.9 6.1 6.6e-05 21.9 4.2 2.4 2 1 0 2 2 2 1 Mammalian taste receptor protein (TAS2R) DUF2909 PF11137.3 EMC86353.1 - 0.029 14.0 5.1 0.031 13.9 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2909) MSC PF09402.5 EMC86353.1 - 0.11 11.1 3.7 0.22 10.1 2.6 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain SERTA PF06031.8 EMC86354.1 - 9.1e-19 66.4 3.3 1.5e-18 65.7 1.8 1.8 2 0 0 2 2 2 1 SERTA motif Glycohydro_20b2 PF14845.1 EMC86354.1 - 0.035 14.7 0.2 0.051 14.2 0.1 1.4 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like NusB PF01029.13 EMC86354.1 - 0.12 12.3 0.0 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 NusB family Clathrin_bdg PF15045.1 EMC86355.1 - 2.6e-24 84.4 0.2 5.4e-24 83.5 0.2 1.5 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking FEZ PF07763.8 EMC86355.1 - 0.049 13.3 0.5 0.08 12.6 0.4 1.3 1 0 0 1 1 1 0 FEZ-like protein Gln-synt_N PF03951.14 EMC86355.1 - 0.078 12.5 0.1 0.27 10.8 0.1 1.9 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain PDZ PF00595.19 EMC86356.1 - 6.1e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) P-mevalo_kinase PF04275.9 EMC86356.1 - 0.11 12.2 0.4 0.17 11.5 0.3 1.3 1 0 0 1 1 1 0 Phosphomevalonate kinase Orn_DAP_Arg_deC PF00278.17 EMC86357.1 - 0.38 10.4 15.2 3.4 7.4 0.1 6.7 2 1 4 6 6 6 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Collagen PF01391.13 EMC86358.1 - 1.1e-06 28.0 22.5 4.5e-06 26.1 15.6 1.8 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Rhomboid PF01694.17 EMC86359.1 - 4.3e-15 56.0 6.6 9.1e-15 54.9 4.6 1.4 1 0 0 1 1 1 1 Rhomboid family DUF2393 PF09624.5 EMC86359.1 - 0.17 11.3 0.6 0.34 10.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) C4 PF01413.14 EMC86360.1 - 3.8e-91 300.6 4.9 5.4e-47 158.4 0.2 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.13 EMC86360.1 - 6.9e-74 243.3 294.6 4.2e-10 39.0 16.7 12.9 2 2 10 12 12 12 11 Collagen triple helix repeat (20 copies) Miff PF05644.6 EMC86361.1 - 1.9e-93 312.6 4.6 5.6e-93 311.1 3.2 1.6 1 1 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff dsrm PF00035.20 EMC86362.1 - 0.0023 18.4 0.0 0.0057 17.2 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EMC86362.1 - 0.099 12.6 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease-III-like ArfGap PF01412.13 EMC86363.1 - 1.7e-11 43.9 0.0 3.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Folate_carrier PF01770.13 EMC86364.1 - 2.1e-177 589.7 14.0 2.5e-177 589.4 9.7 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 EMC86364.1 - 1.6e-10 40.2 17.6 1.6e-10 40.2 12.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Herpes_pp38 PF04846.8 EMC86364.1 - 0.014 14.7 0.8 0.1 11.9 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein Folate_carrier PF01770.13 EMC86365.1 - 3.6e-177 588.9 19.6 4.3e-177 588.7 13.6 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 EMC86365.1 - 4.4e-11 42.0 18.5 4.4e-11 42.0 12.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily IL8 PF00048.15 EMC86366.1 - 1.8e-18 66.2 0.1 2.5e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like WD40 PF00400.27 EMC86367.1 - 1e-84 275.6 23.4 1.2e-12 47.1 0.2 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EMC86367.1 - 1.1e-06 27.1 5.3 0.028 12.5 0.0 5.7 1 1 5 7 7 7 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMC86367.1 - 0.0054 16.2 0.5 0.098 12.0 0.4 2.5 1 1 0 1 1 1 1 PQQ-like domain DUF1258 PF06869.7 EMC86367.1 - 0.037 13.0 7.2 0.072 12.1 0.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1258) PID_2 PF14719.1 EMC86368.1 - 9.8e-19 67.6 0.5 1.6e-18 67.0 0.3 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.18 EMC86368.1 - 7.3e-07 29.2 1.4 1.1e-06 28.7 1.0 1.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) EGF PF00008.22 EMC86369.1 - 7.4e-54 179.2 124.7 2.9e-08 33.5 7.6 9.6 9 0 0 9 9 9 9 EGF-like domain EGF_2 PF07974.8 EMC86369.1 - 4.1e-19 68.4 147.4 0.00063 19.8 4.9 9.7 9 0 0 9 9 9 9 EGF-like domain hEGF PF12661.2 EMC86369.1 - 1.9e-16 58.9 73.3 0.0096 15.9 0.5 10.1 9 0 0 9 9 9 7 Human growth factor-like EGF EGF_CA PF07645.10 EMC86369.1 - 2.6e-07 30.5 128.5 1.7e-05 24.6 5.3 9.7 3 1 6 9 9 9 6 Calcium-binding EGF domain EGF_3 PF12947.2 EMC86369.1 - 2e-05 24.4 118.2 0.0077 16.1 5.9 9.6 8 1 1 9 9 9 6 EGF domain FXa_inhibition PF14670.1 EMC86369.1 - 0.009 16.1 10.1 0.009 16.1 7.0 9.6 4 2 5 9 9 9 4 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC86369.1 - 0.044 13.4 0.5 0.044 13.4 0.4 10.1 9 1 0 9 9 9 0 Complement Clr-like EGF-like Laminin_EGF PF00053.19 EMC86369.1 - 3.6 7.6 119.0 12 5.8 6.3 9.5 2 1 6 8 8 8 0 Laminin EGF-like (Domains III and V) HECT PF00632.20 EMC86370.1 - 3e-94 315.7 0.8 6.1e-94 314.7 0.0 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 EMC86370.1 - 0.0003 20.1 0.1 0.00077 18.8 0.1 1.7 1 0 0 1 1 1 1 WWE domain F-box PF00646.28 EMC86371.1 - 6.5e-11 41.6 2.8 8.2e-11 41.2 0.7 2.1 2 1 1 3 3 3 1 F-box domain F-box-like PF12937.2 EMC86371.1 - 1.1e-10 41.0 0.2 2.4e-10 39.9 0.1 1.6 2 0 0 2 2 2 1 F-box-like PRANC PF09372.5 EMC86371.1 - 0.033 14.1 0.8 0.19 11.7 0.0 2.2 1 1 1 2 2 2 0 PRANC domain MFS_1 PF07690.11 EMC86372.1 - 3.1e-49 167.5 22.1 7.7e-39 133.3 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0154 PF03672.8 EMC86372.1 - 0.27 10.8 2.6 2.2 7.9 0.4 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) zf-H2C2_2 PF13465.1 EMC86373.1 - 3.5e-27 93.3 75.5 8e-06 25.8 0.5 11.6 12 0 0 12 12 12 7 Zinc-finger double domain BTB PF00651.26 EMC86373.1 - 6.9e-22 77.5 0.1 1.7e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 EMC86373.1 - 2e-19 68.6 82.4 0.00022 21.3 2.2 11.1 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMC86373.1 - 9.3e-09 35.1 49.6 0.00016 21.7 0.0 10.2 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMC86373.1 - 5.6e-07 29.4 86.3 0.038 14.3 1.6 11.6 11 0 0 11 11 11 8 C2H2-type zinc finger zf-met PF12874.2 EMC86373.1 - 8e-06 25.8 0.3 8e-06 25.8 0.2 8.9 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC86373.1 - 1.2 9.1 60.1 0.071 13.0 0.6 9.7 10 0 0 10 10 10 0 C2H2-type zinc finger RasGAP PF00616.14 EMC86374.1 - 1.2e-42 145.8 0.2 5.6e-42 143.6 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EMC86374.1 - 3e-31 107.1 3.2 1.2e-16 60.3 0.9 3.3 2 1 0 2 2 2 2 C2 domain PH PF00169.24 EMC86374.1 - 2.3e-15 56.6 6.0 3.4e-15 56.1 0.4 2.8 2 0 0 2 2 2 1 PH domain BTK PF00779.14 EMC86374.1 - 3e-13 49.1 1.1 5.7e-13 48.2 0.8 1.5 1 0 0 1 1 1 1 BTK motif CEP76-C2 PF15627.1 EMC86374.1 - 0.00055 19.4 0.4 0.95 8.9 0.0 2.5 2 0 0 2 2 2 2 CEP76 C2 domain PH_8 PF15409.1 EMC86374.1 - 0.00076 19.5 0.1 0.0029 17.6 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EMC86374.1 - 0.039 14.2 2.6 0.22 11.7 1.0 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain DNA_pol3_beta_2 PF02767.11 EMC86374.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain zf-rbx1 PF12678.2 EMC86375.1 - 5.1e-14 52.1 15.9 5.8e-14 51.9 11.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC86375.1 - 1.3e-08 34.5 10.9 1.4e-08 34.4 7.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMC86375.1 - 2.2e-08 33.7 12.5 3.1e-08 33.2 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC86375.1 - 1.5e-05 24.5 9.7 2.2e-05 24.0 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC86375.1 - 0.0014 18.2 13.6 0.0028 17.2 9.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC86375.1 - 0.0016 18.4 12.3 0.0018 18.2 8.1 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC86375.1 - 0.0026 17.4 12.2 0.0043 16.7 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EMC86375.1 - 0.028 14.2 4.8 0.035 13.8 3.3 1.1 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.9 EMC86375.1 - 0.046 13.2 0.2 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn_Tnp_IS1 PF03811.8 EMC86375.1 - 0.15 11.5 0.2 0.15 11.5 0.1 2.3 2 1 0 2 2 2 0 InsA N-terminal domain PHD PF00628.24 EMC86375.1 - 1.2 8.8 14.5 2.3 7.9 10.0 1.5 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EMC86375.1 - 1.6 8.5 13.3 3.4 7.4 5.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EMC86375.1 - 2.9 7.5 13.3 1.5 8.4 7.9 1.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 EMC86376.1 - 9.4e-61 205.2 0.2 1.4e-60 204.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86376.1 - 8.2e-34 116.8 0.8 1.6e-33 115.8 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RGS PF00615.14 EMC86376.1 - 2.4e-13 50.1 4.1 3.2e-13 49.7 1.2 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 EMC86376.1 - 0.00013 21.0 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF469 PF04320.9 EMC86376.1 - 0.023 15.4 0.4 0.064 14.0 0.1 1.9 2 0 0 2 2 2 0 Protein with unknown function (DUF469) Na_K-ATPase PF00287.13 EMC86377.1 - 1.9e-99 332.1 0.1 2.1e-99 331.9 0.1 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DP PF08781.5 EMC86378.1 - 7.4e-58 194.2 1.3 1.7e-57 193.1 0.9 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.15 EMC86378.1 - 8.8e-27 92.4 0.2 8.8e-27 92.4 0.2 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain FGGY_N PF00370.16 EMC86379.1 - 8.2e-38 130.1 0.0 2.9e-36 125.0 0.0 2.4 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EMC86379.1 - 1.1e-30 106.7 0.0 1.8e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain XRN_N PF03159.13 EMC86380.1 - 1.7e-91 305.8 0.1 3.3e-91 304.9 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PI3_PI4_kinase PF00454.22 EMC86381.1 - 3.8e-60 203.2 0.2 1.8e-59 201.0 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EMC86381.1 - 4.5e-41 140.9 5.3 4.5e-41 140.9 3.6 3.4 3 1 0 3 3 3 1 FAT domain UME PF08064.8 EMC86381.1 - 1.8e-27 95.3 0.4 1.8e-27 95.3 0.2 4.3 5 0 0 5 5 5 1 UME (NUC010) domain FATC PF02260.15 EMC86381.1 - 1.4e-12 46.8 0.1 3.3e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EMC86381.1 - 1.4e-09 37.1 4.5 0.075 13.1 0.0 8.3 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EMC86381.1 - 8.1e-07 29.2 0.1 1.2 9.4 0.0 4.8 4 0 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EMC86381.1 - 0.11 12.9 1.5 23 5.6 0.0 5.2 4 0 0 4 4 4 0 HEAT-like repeat CH PF00307.26 EMC86382.1 - 5.9e-80 264.3 2.4 4.8e-23 81.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EMC86382.1 - 3.4e-14 52.7 0.0 1.1e-13 51.0 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC86382.1 - 7.4e-13 46.7 1.5 2e-05 23.5 0.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC86382.1 - 1.7e-08 33.6 0.2 0.0008 19.0 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain CAMSAP_CH PF11971.3 EMC86382.1 - 6.2e-07 28.9 0.0 0.00012 21.7 0.0 3.4 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_8 PF13833.1 EMC86382.1 - 9.5e-07 28.3 0.1 0.014 15.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC86382.1 - 8.6e-06 24.8 6.7 0.021 14.1 0.0 4.1 3 1 1 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 EMC86382.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region TRP_2 PF08344.6 EMC86383.1 - 2.7e-27 94.4 2.6 6.2e-27 93.3 1.8 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.26 EMC86383.1 - 1.8e-20 73.0 15.2 6e-20 71.3 10.2 2.1 3 0 0 3 3 3 1 Ion transport protein Ank_2 PF12796.2 EMC86383.1 - 7.1e-08 32.6 1.0 2.8e-05 24.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC86383.1 - 2.4e-06 27.8 0.3 0.021 15.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC86383.1 - 0.0011 18.7 0.2 0.48 10.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EMC86383.1 - 0.004 17.3 0.1 2 8.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF2407_C PF13373.1 EMC86383.1 - 0.0092 15.9 0.1 0.089 12.7 0.0 2.6 2 0 0 2 2 2 1 DUF2407 C-terminal domain CUB PF00431.15 EMC86384.1 - 1.4e-61 205.3 0.0 1.8e-30 105.2 0.0 2.3 2 0 0 2 2 2 2 CUB domain NTR PF01759.16 EMC86384.1 - 1.2e-15 56.9 1.0 1.6e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 UNC-6/NTR/C345C module CUB_2 PF02408.15 EMC86384.1 - 4.2e-08 32.7 0.1 0.002 17.6 0.0 2.7 2 0 0 2 2 2 2 CUB-like domain TIMP PF00965.12 EMC86384.1 - 0.0014 18.2 0.4 0.0027 17.3 0.3 1.4 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Surp PF01805.15 EMC86385.1 - 3.6e-20 71.3 0.9 6.6e-20 70.5 0.1 1.9 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.17 EMC86385.1 - 7.7e-15 54.2 0.0 1.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC86385.1 - 3.1e-10 39.9 0.0 7.6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.7 EMC86385.1 - 5e-09 35.8 4.1 5e-09 35.8 2.8 3.6 3 0 0 3 3 3 1 cwf21 domain CTK3 PF12243.3 EMC86385.1 - 4.2e-05 23.2 0.2 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 EMC86385.1 - 0.00022 20.9 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EMC86385.1 - 0.0066 16.6 0.5 0.05 13.8 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Nup35_RRM_2 PF14605.1 EMC86385.1 - 0.18 11.5 0.0 0.55 10.0 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sulfotransfer_1 PF00685.22 EMC86386.1 - 3.1e-13 49.6 0.0 3.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Na_H_Exchanger PF00999.16 EMC86387.1 - 1.5e-78 264.0 26.1 2.5e-78 263.2 18.1 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Scramblase PF03803.10 EMC86388.1 - 5e-95 316.7 0.0 6e-95 316.5 0.0 1.0 1 0 0 1 1 1 1 Scramblase Scramblase PF03803.10 EMC86389.1 - 2.6e-70 235.9 0.4 2.9e-70 235.8 0.3 1.0 1 0 0 1 1 1 1 Scramblase zf-H2C2_2 PF13465.1 EMC86391.1 - 2e-22 78.2 30.2 8.3e-09 35.3 0.2 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC86391.1 - 4e-19 67.7 33.0 8.4e-06 25.8 0.1 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC86391.1 - 3.8e-16 58.1 24.2 0.00088 19.4 0.1 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC86391.1 - 2e-06 27.7 13.3 0.21 11.8 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC86391.1 - 0.024 14.5 12.6 0.16 11.9 1.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EMC86391.1 - 9.9 6.5 20.4 0.64 10.3 0.5 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMC86392.1 - 5.7e-23 80.0 30.4 1.5e-08 34.4 0.2 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC86392.1 - 3.9e-20 70.8 32.0 1.5e-05 25.0 0.1 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC86392.1 - 1.2e-17 62.8 21.9 0.0016 18.6 0.1 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC86392.1 - 2.2e-08 33.9 15.2 0.0021 18.1 0.2 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC86392.1 - 0.00035 20.6 13.5 0.0034 17.5 0.9 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC86392.1 - 0.017 15.0 9.5 0.2 11.5 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger 7tm_1 PF00001.16 EMC86394.1 - 1.2e-61 208.1 23.2 1.5e-61 207.7 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86394.1 - 1.7e-09 37.1 25.2 2.5e-09 36.6 17.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 60KD_IMP PF02096.15 EMC86394.1 - 0.17 11.5 5.5 0.39 10.3 3.8 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein 7TM_GPCR_Srx PF10328.4 EMC86394.1 - 2.3 7.2 34.3 2.1 7.4 19.9 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Peptidase_M14 PF00246.19 EMC86395.1 - 2e-87 293.3 0.0 2.5e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMC86395.1 - 6.4e-19 67.4 0.3 1.2e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide ABM PF03992.11 EMC86395.1 - 0.022 14.7 0.2 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase 7tm_4 PF13853.1 EMC86396.1 - 3.7e-61 205.1 9.6 3.7e-61 205.1 6.7 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC86396.1 - 7.6e-36 123.5 15.0 9.4e-36 123.2 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86396.1 - 0.00069 18.8 15.3 0.0011 18.2 10.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1240 PF06836.7 EMC86396.1 - 1.2 9.3 5.7 0.29 11.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) eIF3_N PF09440.5 EMC86397.1 - 7.8e-30 103.7 4.3 9.9e-30 103.4 1.2 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EMC86397.1 - 1e-18 67.5 0.0 4.8e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EMC86397.1 - 0.022 14.5 2.5 0.067 12.9 0.0 2.9 4 0 0 4 4 4 0 COP9 signalosome, subunit CSN8 Metal_hydrol PF10118.4 EMC86397.1 - 0.073 12.5 0.1 7.4 5.9 0.0 2.9 3 0 0 3 3 3 0 Predicted metal-dependent hydrolase HD_assoc PF13286.1 EMC86397.1 - 0.14 12.4 1.4 2.5 8.4 0.1 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain TPR_14 PF13428.1 EMC86398.1 - 6.1e-12 45.0 7.8 0.0041 17.6 0.2 5.6 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86398.1 - 1.9e-11 44.3 4.7 0.003 18.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC86398.1 - 8.1e-10 37.8 12.4 0.00017 21.2 0.4 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86398.1 - 6.4e-09 36.0 9.5 1.8e-05 24.9 0.2 3.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC86398.1 - 7.5e-09 35.1 13.3 5.5e-05 22.7 3.9 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMC86398.1 - 2e-06 27.1 5.6 0.12 12.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC86398.1 - 0.00035 20.1 12.2 0.021 14.5 0.0 4.5 5 1 1 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.3 EMC86398.1 - 0.00048 19.0 3.2 0.00048 19.0 2.3 2.4 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.1 EMC86398.1 - 0.0026 17.6 17.9 0.092 12.6 3.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC86398.1 - 0.0036 17.1 3.7 2.1 8.2 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC86398.1 - 0.0076 15.9 2.0 3.6 7.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC86398.1 - 0.0089 16.4 8.0 8.7 7.0 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMC86398.1 - 0.012 15.6 1.9 0.16 12.1 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC86398.1 - 0.015 15.4 12.6 0.023 14.8 2.7 3.5 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EMC86398.1 - 0.11 12.3 4.2 8.8 6.3 0.1 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EMC86398.1 - 0.14 12.3 9.5 0.98 9.6 0.3 2.8 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_17 PF13431.1 EMC86398.1 - 0.33 11.2 11.8 0.93 9.8 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Neurensin PF14927.1 EMC86399.1 - 5.4e-09 35.5 0.0 7.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Neurensin 7tm_1 PF00001.16 EMC86400.1 - 4e-56 190.0 25.7 6.1e-56 189.4 17.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86400.1 - 1.6e-10 40.6 24.3 2.9e-10 39.7 16.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC86400.1 - 0.0019 17.3 28.9 0.022 13.8 20.0 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Sarcoglycan_2 PF05510.8 EMC86400.1 - 0.044 12.0 0.0 0.081 11.2 0.0 1.4 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon CS PF04969.11 EMC86401.1 - 9.2e-20 70.9 1.5 1.8e-19 70.0 1.0 1.5 1 0 0 1 1 1 1 CS domain EnY2 PF10163.4 EMC86402.1 - 4.9e-35 119.3 0.4 5.5e-35 119.1 0.3 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 SAP PF02037.22 EMC86402.1 - 7.2 6.2 6.4 15 5.2 0.0 3.6 4 0 0 4 4 4 0 SAP domain DUF1682 PF07946.9 EMC86403.1 - 8.2 5.1 15.8 12 4.6 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Syntaphilin PF15290.1 EMC86404.1 - 2.1e-122 408.3 15.6 3.7e-122 407.5 10.8 1.4 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp DUF812 PF05667.6 EMC86404.1 - 0.00043 18.9 6.0 0.0007 18.2 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IncA PF04156.9 EMC86404.1 - 0.0064 16.1 10.6 0.011 15.3 7.3 1.4 1 0 0 1 1 1 1 IncA protein MAD PF05557.8 EMC86404.1 - 0.0073 14.4 18.8 0.011 13.9 13.0 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF3584 PF12128.3 EMC86404.1 - 0.068 10.4 14.5 0.096 10.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EMC86404.1 - 0.16 10.5 15.5 0.28 9.7 10.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 EMC86404.1 - 0.44 8.9 12.7 0.71 8.2 8.8 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 EMC86404.1 - 0.78 9.4 19.5 24 4.6 13.5 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein BTV_NS2 PF04514.7 EMC86404.1 - 0.95 8.2 10.1 1.5 7.6 7.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HR1 PF02185.11 EMC86404.1 - 1.3 8.7 15.6 0.094 12.4 0.8 3.0 2 1 1 3 3 3 0 Hr1 repeat DUF342 PF03961.8 EMC86404.1 - 1.7 6.9 11.8 2.7 6.3 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sec8_exocyst PF04048.9 EMC86404.1 - 1.9 8.1 11.2 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Ly49 PF08391.5 EMC86404.1 - 2.4 8.3 7.9 2.7 8.1 4.1 2.1 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Sec2p PF06428.6 EMC86404.1 - 4.7 7.1 17.5 7.5 6.4 2.1 3.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Hydrophobin PF01185.13 EMC86405.1 - 0.085 13.3 0.2 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Fungal hydrophobin Ion_trans PF00520.26 EMC86406.1 - 5.6e-34 117.1 4.4 1.1e-33 116.2 3.0 1.5 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.17 EMC86406.1 - 1.8e-23 82.5 0.0 4.2e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC86406.1 - 1.5e-12 47.0 6.3 1.5e-12 47.0 4.4 2.1 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC86406.1 - 0.0019 16.7 2.8 0.01 14.3 0.0 2.1 1 1 1 2 2 2 2 Polycystin cation channel Yae1_N PF09811.4 EMC86407.1 - 7.2e-41 137.4 152.4 1.5e+04 -113.2 105.6 12.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Arrestin_C PF02752.17 EMC86408.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.8 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Ribosomal_60s PF00428.14 EMC86408.1 - 0.45 10.9 11.3 0.74 10.2 7.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Atrophin-1 PF03154.10 EMC86408.1 - 0.88 7.6 11.5 1.1 7.3 8.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family CUB PF00431.15 EMC86410.1 - 0 1081.2 0.0 1.8e-25 89.1 0.0 14.3 14 0 0 14 14 14 14 CUB domain Sushi PF00084.15 EMC86410.1 - 5.3e-253 817.6 182.0 4.4e-11 42.9 0.7 28.6 28 0 0 28 28 28 28 Sushi domain (SCR repeat) CUB_2 PF02408.15 EMC86410.1 - 4.4e-24 84.3 11.9 0.015 14.8 0.2 12.3 13 0 0 13 13 13 8 CUB-like domain PHZA_PHZB PF03284.8 EMC86410.1 - 3.5 6.7 3.6 2e+02 0.9 0.0 4.8 7 0 0 7 7 7 0 Phenazine biosynthesis protein A/B zf-H2C2_5 PF13909.1 EMC86411.1 - 1.5e-07 31.2 73.6 0.00045 20.2 1.6 9.0 9 0 0 9 9 9 7 C2H2-type zinc-finger domain Fcf1 PF04900.7 EMC86412.1 - 4.7e-28 97.2 0.4 1.5e-27 95.6 0.0 2.0 2 1 0 2 2 2 1 Fcf1 Rad21_Rec8_N PF04825.8 EMC86413.1 - 1.4e-43 147.3 0.0 2.7e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EMC86413.1 - 8.3e-23 79.3 0.2 3.3e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EMC86413.1 - 2.8e-08 33.6 1.2 7.3e-08 32.2 0.2 2.1 2 0 0 2 2 2 1 ScpA/B protein V-ATPase_G PF03179.10 EMC86413.1 - 0.28 11.5 7.8 0.06 13.6 2.7 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Cation_efflux PF01545.16 EMC86414.1 - 8.8e-56 189.0 18.0 1.1e-55 188.7 12.4 1.0 1 0 0 1 1 1 1 Cation efflux family Med30 PF11315.3 EMC86415.1 - 1.4e-66 223.2 1.8 1.6e-66 223.0 1.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 UPF0449 PF15136.1 EMC86415.1 - 0.094 12.9 4.0 0.13 12.5 1.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 AKNA PF12443.3 EMC86415.1 - 0.1 12.6 0.9 0.5 10.4 0.2 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor NYD-SP28_assoc PF14775.1 EMC86415.1 - 0.64 9.7 5.4 1.4 8.7 3.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Glyco_transf_64 PF09258.5 EMC86416.1 - 1.7e-82 276.2 7.7 2e-62 210.5 0.8 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 64 domain Exostosin PF03016.10 EMC86416.1 - 6.2e-26 91.1 0.1 1.4e-25 89.9 0.0 1.6 2 0 0 2 2 2 1 Exostosin family DNA_pol_E_B PF04042.11 EMC86416.1 - 0.027 13.7 0.0 0.59 9.3 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase alpha/epsilon subunit B KicB PF03882.9 EMC86416.1 - 0.082 11.5 0.2 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 KicB killing factor SAM_2 PF07647.12 EMC86417.1 - 1.2e-17 63.5 1.0 1.7e-17 62.9 0.7 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC86417.1 - 2.8e-11 43.3 0.9 4.2e-11 42.8 0.6 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC86417.1 - 1.2e-08 34.6 0.1 1.8e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PAPS_reduct PF01507.14 EMC86417.1 - 0.11 12.3 0.3 0.24 11.1 0.1 1.6 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Death PF00531.17 EMC86418.1 - 2e-18 65.9 1.2 4.2e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Death domain TNFR_c6 PF00020.13 EMC86418.1 - 6.1e-14 51.8 37.3 2.9e-07 30.4 9.1 4.9 5 0 0 5 5 5 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 EMC86418.1 - 0.03 13.8 1.7 0.03 13.8 1.1 4.2 1 1 3 4 4 4 0 GCC2 and GCC3 tRNA_NucTran2_2 PF13735.1 EMC86418.1 - 0.54 10.0 3.6 1.2 8.9 0.4 2.4 1 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Lectin_C PF00059.16 EMC86419.1 - 8.9e-18 64.8 0.0 1.3e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.13 EMC86419.1 - 6.6e-12 44.7 57.1 7.5e-08 31.8 16.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MARVEL PF01284.18 EMC86420.1 - 1.3e-12 47.7 18.9 1.5e-12 47.5 13.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.1 EMC86420.1 - 0.59 9.3 8.7 0.87 8.8 6.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_U4 PF03419.8 EMC86420.1 - 1.2 8.1 9.2 1.5 7.8 4.6 1.8 1 1 1 2 2 2 0 Sporulation factor SpoIIGA DUF3687 PF12459.3 EMC86420.1 - 3.4 6.9 9.4 0.21 10.8 1.5 2.3 1 1 1 2 2 2 0 D-Ala-teichoic acid biosynthesis protein Cys_knot PF00007.17 EMC86422.1 - 1.5e-15 57.1 12.9 1.5e-15 57.1 9.0 2.8 3 0 0 3 3 3 1 Cystine-knot domain VWC PF00093.13 EMC86422.1 - 6.7e-12 45.3 8.9 6.7e-12 45.3 6.2 4.2 2 1 0 2 2 2 1 von Willebrand factor type C domain TSP_1 PF00090.14 EMC86422.1 - 1.8e-09 37.5 9.7 1.8e-09 37.5 6.7 2.6 3 1 0 3 3 3 1 Thrombospondin type 1 domain Phosphodiest PF01663.17 EMC86423.1 - 1.5e-74 251.5 0.1 1.7e-38 132.9 0.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 EMC86423.1 - 1.3e-19 69.9 45.2 2.5e-10 40.1 9.5 3.2 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.18 EMC86423.1 - 1.3e-12 47.7 0.0 3e-12 46.6 0.0 1.6 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.18 EMC86423.1 - 5.4e-05 22.5 0.0 0.016 14.4 0.0 2.2 2 0 0 2 2 2 2 Sulfatase DUF2036 PF09724.4 EMC86424.1 - 8.9e-95 317.5 3.5 1e-94 317.3 2.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RepA_N PF06970.6 EMC86424.1 - 0.014 15.1 0.3 1 9.2 0.0 3.1 3 0 0 3 3 3 0 Replication initiator protein A (RepA) N-terminus DEP PF00610.16 EMC86425.1 - 2.2e-46 155.4 1.9 4.1e-25 87.3 0.2 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_2 PF13180.1 EMC86425.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.19 EMC86425.1 - 0.058 13.5 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Ribonuclease_3 PF00636.21 EMC86425.1 - 0.16 12.4 0.4 0.34 11.3 0.1 1.6 2 0 0 2 2 2 0 Ribonuclease III domain VWA PF00092.23 EMC86426.1 - 5.5e-104 345.4 0.2 4.4e-51 173.1 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain fn3 PF00041.16 EMC86426.1 - 1.9e-95 313.1 9.9 1.5e-13 50.6 0.0 8.3 8 0 0 8 8 8 8 Fibronectin type III domain Collagen PF01391.13 EMC86426.1 - 3.4e-37 125.8 167.1 4.6e-09 35.6 17.8 5.4 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 EMC86426.1 - 4.2e-23 82.3 0.0 1.7e-11 44.5 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain Laminin_G_3 PF13385.1 EMC86426.1 - 0.0067 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SusE PF14292.1 EMC86426.1 - 0.049 13.4 3.8 14 5.5 0.0 4.2 5 0 0 5 5 5 0 SusE outer membrane protein Ribosomal_L13 PF00572.13 EMC86427.1 - 1.8e-06 27.9 0.1 2.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 PH PF00169.24 EMC86428.1 - 2.1e-10 40.7 0.0 3e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 PH domain Glyco_tranf_2_3 PF13641.1 EMC86429.1 - 4.1e-19 69.2 0.0 9.6e-18 64.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 EMC86429.1 - 2.9e-18 65.5 5.8 3.8e-14 51.9 2.6 3.5 2 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.21 EMC86429.1 - 1.4e-10 41.0 0.0 0.00043 20.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EMC86429.1 - 7.8e-08 32.2 19.4 9.3e-07 28.7 13.5 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EMC86429.1 - 0.00055 19.2 0.0 0.0013 18.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Homeobox PF00046.24 EMC86431.1 - 8.7e-30 102.1 18.3 1.4e-08 34.2 0.2 4.4 4 0 0 4 4 4 4 Homeobox domain Homeobox_KN PF05920.6 EMC86431.1 - 2e-18 65.7 9.6 0.0017 18.0 0.2 4.8 4 0 0 4 4 4 4 Homeobox KN domain Homez PF11569.3 EMC86431.1 - 2.7e-08 32.7 7.6 0.089 11.8 0.0 4.4 4 0 0 4 4 4 4 Homeodomain leucine-zipper encoding, Homez zf-H2C2_5 PF13909.1 EMC86431.1 - 9.4e-05 22.4 9.4 0.067 13.4 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain DUF3505 PF12013.3 EMC86431.1 - 0.0051 17.0 1.0 0.68 10.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) HTH_26 PF13443.1 EMC86431.1 - 0.056 13.6 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain zf-C2H2 PF00096.21 EMC86431.1 - 0.19 12.1 8.1 2.9 8.4 0.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 EMC86431.1 - 0.6 10.2 4.8 1.9 8.6 3.4 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EMC86431.1 - 0.75 10.2 4.9 3.3 8.2 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC86431.1 - 1.5 9.2 9.4 4.3 7.8 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain DUF1669 PF07894.7 EMC86432.1 - 1.3e-99 333.0 0.1 1.6e-99 332.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 EMC86432.1 - 0.0027 17.4 0.1 0.0064 16.2 0.0 1.6 2 0 0 2 2 2 1 PLD-like domain TPR_14 PF13428.1 EMC86433.1 - 0.099 13.3 0.0 17 6.4 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86433.1 - 0.18 12.4 0.6 2.4 8.9 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMC86433.1 - 0.31 11.5 1.3 0.46 11.0 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Homeobox PF00046.24 EMC86434.1 - 1.6e-36 123.6 19.0 6.6e-08 32.0 0.1 5.4 5 0 0 5 5 5 5 Homeobox domain Homez PF11569.3 EMC86434.1 - 3.9e-32 109.0 6.5 8.5e-22 75.9 0.2 5.2 5 0 0 5 5 5 4 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EMC86434.1 - 3.2e-22 77.9 6.0 9.9e-05 21.9 0.0 5.7 5 0 0 5 5 5 5 Homeobox KN domain zf-C2H2_4 PF13894.1 EMC86434.1 - 0.63 10.5 5.1 3.8 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC86434.1 - 0.63 10.4 7.2 4.3 7.8 0.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA PF00004.24 EMC86435.1 - 1.2e-47 161.4 0.0 3e-41 140.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 EMC86435.1 - 2.6e-20 72.1 0.0 9.2e-20 70.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.1 EMC86435.1 - 9e-08 32.3 0.2 9.7e-07 28.9 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EMC86435.1 - 3.2e-06 26.6 0.0 0.00015 21.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EMC86435.1 - 1.1e-05 25.6 0.2 0.0017 18.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.9 EMC86435.1 - 4e-05 23.5 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Brr6_like_C_C PF10104.4 EMC86435.1 - 0.00012 21.5 0.3 0.00028 20.3 0.2 1.6 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain AAA_19 PF13245.1 EMC86435.1 - 0.00039 20.1 0.0 0.029 14.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EMC86435.1 - 0.0015 18.2 0.0 0.067 12.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMC86435.1 - 0.0024 18.7 0.0 0.011 16.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC86435.1 - 0.003 17.8 0.0 0.03 14.6 0.0 2.7 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EMC86435.1 - 0.0038 17.3 0.0 0.029 14.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EMC86435.1 - 0.017 14.5 0.0 0.083 12.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EMC86435.1 - 0.022 14.6 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EMC86435.1 - 0.024 13.5 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 EMC86435.1 - 0.025 13.6 0.0 0.093 11.7 0.0 2.0 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 EMC86435.1 - 0.032 14.2 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 EMC86435.1 - 0.067 13.0 0.0 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EMC86435.1 - 0.071 12.2 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EMC86435.1 - 0.08 11.6 0.0 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus AAA_28 PF13521.1 EMC86435.1 - 0.088 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Nt_Gln_amidase PF09764.4 EMC86437.1 - 6.4e-65 217.8 0.0 7.2e-65 217.7 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase F-box-like PF12937.2 EMC86438.1 - 0.0022 17.6 0.7 0.0091 15.7 0.2 2.4 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.6 EMC86438.1 - 0.017 15.5 0.1 0.062 13.6 0.1 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.28 EMC86438.1 - 0.033 13.8 0.7 0.15 11.7 0.1 2.5 2 0 0 2 2 2 0 F-box domain DUF4047 PF13256.1 EMC86438.1 - 0.06 13.3 1.6 0.22 11.4 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Kelch_1 PF01344.20 EMC86439.1 - 2e-51 171.2 0.5 6.9e-11 41.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC86439.1 - 1.5e-36 123.0 0.7 8.7e-06 25.6 0.0 6.4 2 2 4 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EMC86439.1 - 2.7e-27 94.2 0.0 0.0015 18.6 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC86439.1 - 4.9e-26 90.2 0.1 4.3e-05 23.1 0.1 6.9 4 3 2 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 EMC86439.1 - 1.7e-25 89.1 0.3 3.4e-25 88.1 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EMC86439.1 - 6.6e-24 83.7 0.3 6.6e-24 83.7 0.2 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 EMC86439.1 - 1.8e-22 78.1 0.1 0.00065 19.3 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMC86439.1 - 8e-21 73.5 1.3 0.0004 20.2 0.0 6.5 6 0 0 6 6 6 5 Kelch motif DUF3342 PF11822.3 EMC86439.1 - 0.0013 17.9 0.4 0.0022 17.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) DUF1668 PF07893.8 EMC86439.1 - 0.002 17.3 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1668) Skp1_POZ PF03931.10 EMC86439.1 - 0.014 15.4 0.0 0.17 11.9 0.0 2.6 3 0 0 3 3 3 0 Skp1 family, tetramerisation domain Annexin PF00191.15 EMC86440.1 - 4.6e-101 330.7 14.0 1.5e-26 92.0 0.1 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 EMC86440.1 - 0.0014 18.7 1.0 6 7.1 0.0 3.8 4 0 0 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FAM91_C PF14648.1 EMC86441.1 - 3.5e-200 665.5 0.0 4.5e-200 665.2 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.1 EMC86441.1 - 1.9e-143 477.1 0.3 2.7e-143 476.6 0.2 1.1 1 0 0 1 1 1 1 FAM91 N-terminus C2 PF00168.25 EMC86442.1 - 7.5e-69 227.6 1.0 2.3e-14 52.9 0.0 7.7 6 1 0 6 6 6 6 C2 domain FerB PF08150.7 EMC86442.1 - 1.3e-31 108.5 0.1 3.4e-31 107.1 0.1 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.7 EMC86442.1 - 6.6e-28 96.5 0.0 1.7e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain Synaptobrevin PF00957.16 EMC86442.1 - 1.8 8.2 6.7 4.1 7.0 4.7 1.6 1 0 0 1 1 1 0 Synaptobrevin TRC8_N PF13705.1 EMC86443.1 - 6.3e-162 539.6 33.1 7.7e-162 539.4 23.0 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.1 EMC86443.1 - 3.5e-11 42.7 9.2 3.5e-11 42.7 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMC86443.1 - 2.7e-08 33.7 6.6 2.7e-08 33.7 4.6 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC86443.1 - 7.1e-07 29.1 7.9 7.1e-07 29.1 5.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC86443.1 - 1.3e-06 27.9 8.0 1.3e-06 27.9 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC86443.1 - 4e-06 26.4 4.7 4e-06 26.4 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC86443.1 - 1.2e-05 24.9 7.5 1.2e-05 24.9 5.2 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC86443.1 - 5.9e-05 22.8 5.7 0.00082 19.1 4.0 2.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EMC86443.1 - 0.055 13.4 8.5 1.7 8.6 5.9 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EMC86443.1 - 0.16 12.1 3.4 0.47 10.6 2.3 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-P11 PF03854.9 EMC86443.1 - 0.48 9.9 5.4 2 7.9 3.7 2.1 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 EMC86443.1 - 2.9 7.7 5.9 0.45 10.3 0.8 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TatD_DNase PF01026.16 EMC86444.1 - 1.2e-52 178.6 0.0 1.5e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase IMD PF08397.6 EMC86445.1 - 3.1e-94 314.3 3.1 4e-94 314.0 2.1 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain Gp58 PF07902.6 EMC86445.1 - 0.12 10.6 0.7 0.15 10.2 0.5 1.1 1 0 0 1 1 1 0 gp58-like protein Bap31 PF05529.7 EMC86445.1 - 3.6 7.0 5.1 5.5 6.4 3.0 1.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like SE PF08491.5 EMC86446.1 - 1.1e-110 368.7 0.0 1.5e-110 368.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EMC86446.1 - 7e-21 74.6 0.0 1.4e-20 73.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC86446.1 - 2e-13 49.9 0.1 7.2e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC86446.1 - 9e-05 22.8 0.1 0.0002 21.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC86446.1 - 0.00011 21.1 0.1 0.21 10.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMC86446.1 - 0.0013 18.7 0.1 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EMC86446.1 - 0.0033 17.4 0.1 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EMC86446.1 - 0.0039 16.8 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 EMC86446.1 - 0.0066 15.6 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Thi4 PF01946.12 EMC86446.1 - 0.011 14.8 0.0 0.031 13.3 0.0 1.6 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 EMC86446.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EMC86446.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EMC86446.1 - 0.021 13.5 0.2 2.3 6.7 0.1 2.5 2 1 1 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EMC86446.1 - 0.022 14.6 0.0 0.04 13.7 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EMC86446.1 - 0.027 13.4 0.1 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EMC86446.1 - 0.043 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EMC86446.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMC86446.1 - 0.081 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Strumpellin PF10266.4 EMC86447.1 - 0 1576.2 23.5 0 1576.0 16.3 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin EF-hand_9 PF14658.1 EMC86447.1 - 0.064 13.1 0.1 0.46 10.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain zf-Nse PF11789.3 EMC86448.1 - 1.4e-20 72.5 2.3 2.6e-20 71.6 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EMC86448.1 - 5.7e-09 35.5 1.0 1.6e-08 34.0 0.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EMC86448.1 - 4.7e-05 22.7 2.1 4.7e-05 22.7 1.4 2.1 1 1 1 2 2 2 1 Rtf2 RING-finger zf-MIZ PF02891.15 EMC86448.1 - 0.00027 20.3 1.6 0.00081 18.8 1.1 1.9 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger HalX PF08663.5 EMC86448.1 - 0.0059 16.5 2.2 0.0061 16.5 0.3 1.9 2 0 0 2 2 2 1 HalX domain zf-RING_2 PF13639.1 EMC86448.1 - 0.0062 16.3 0.3 0.0062 16.3 0.2 1.9 2 0 0 2 2 2 1 Ring finger domain Seadorna_VP7 PF07387.6 EMC86448.1 - 0.0076 15.1 1.6 0.01 14.7 1.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 U-box PF04564.10 EMC86448.1 - 0.052 13.5 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 U-box domain THP2 PF09432.5 EMC86448.1 - 0.14 11.9 5.3 0.057 13.2 2.0 1.6 2 0 0 2 2 2 0 Tho complex subunit THP2 Transpos_assoc PF13963.1 EMC86448.1 - 1 9.3 3.9 1.7 8.6 0.1 2.8 2 1 1 3 3 3 0 Transposase-associated domain Pkinase PF00069.20 EMC86449.1 - 1.2e-06 27.8 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Yae1_N PF09811.4 EMC86450.1 - 5.5e-11 41.8 30.4 3.1 7.4 21.1 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal LRAT PF04970.8 EMC86452.1 - 2.8e-13 49.9 0.2 2.6e-11 43.5 0.1 2.3 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 EMC86452.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family DUF134 PF02001.11 EMC86453.1 - 0.0012 18.6 7.0 16 5.4 0.0 5.4 1 1 2 3 3 3 2 Protein of unknown function DUF134 Bacillus_HBL PF05791.6 EMC86453.1 - 0.12 11.7 9.4 15 4.8 0.4 4.2 1 1 4 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DUF1884 PF08967.5 EMC86453.1 - 0.78 9.8 15.3 84 3.3 0.7 5.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1884) Chorion_3 PF05387.6 EMC86453.1 - 6.9 6.0 5.5 24 4.2 0.2 2.1 1 1 1 2 2 2 0 Chorion family 3 IN_DBD_C PF00552.16 EMC86454.1 - 7.7e-15 54.0 0.6 9.9e-15 53.7 0.4 1.1 1 0 0 1 1 1 1 Integrase DNA binding domain Branch PF02485.16 EMC86455.1 - 2e-47 161.3 1.1 2.8e-47 160.9 0.2 1.6 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Arena_nucleocap PF00843.12 EMC86455.1 - 0.13 10.1 0.0 0.17 9.7 0.0 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein Ank_2 PF12796.2 EMC86456.1 - 4.9e-22 78.0 0.1 2e-13 50.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86456.1 - 5.2e-22 76.4 0.1 2.5e-07 30.1 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMC86456.1 - 4.4e-19 68.4 0.0 5.4e-10 39.5 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC86456.1 - 1.1e-14 54.0 0.1 2.2e-07 30.8 0.1 3.0 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86456.1 - 2.6e-13 48.7 0.0 0.00083 19.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat NAD_kinase PF01513.16 EMC86456.1 - 0.018 13.8 0.0 0.046 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-NAD kinase Ank_2 PF12796.2 EMC86457.1 - 4.1e-29 100.7 0.3 4.7e-15 55.6 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC86457.1 - 3.7e-24 84.6 0.5 4.8e-10 39.6 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC86457.1 - 2.8e-18 65.5 0.2 2.3e-08 33.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC86457.1 - 2.7e-17 61.5 0.0 4.5e-08 32.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMC86457.1 - 1.4e-13 49.6 0.0 6.1e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat YiaAB PF05360.9 EMC86457.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 yiaA/B two helix domain HMG-CoA_red PF00368.13 EMC86458.1 - 2.8e-168 559.3 1.5 3.6e-168 559.0 1.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EMC86458.1 - 5.2e-17 61.7 3.6 1.1e-16 60.7 2.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EMC86458.1 - 5.6e-09 34.4 2.2 8.5e-09 33.9 1.5 1.2 1 0 0 1 1 1 1 Patched family IMS PF00817.15 EMC86459.1 - 4.1e-44 149.9 0.0 1.8e-43 147.8 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EMC86459.1 - 2.9e-15 56.3 0.5 8.8e-15 54.7 0.3 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMC86459.1 - 4.2e-09 35.9 0.1 9.8e-09 34.7 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 EMC86459.1 - 0.011 15.9 1.6 0.47 10.6 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain Cdd1 PF11731.3 EMC86459.1 - 0.035 14.0 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Pathogenicity locus zf-Di19 PF05605.7 EMC86459.1 - 0.25 11.5 4.5 11 6.2 0.3 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EMC86459.1 - 0.61 10.5 10.7 0.4 11.1 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.2 EMC86460.1 - 6e-45 151.5 9.7 6.9e-19 67.9 1.6 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86460.1 - 5.3e-42 139.5 7.2 5.9e-08 32.1 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EMC86460.1 - 1.1e-34 118.2 10.9 2.1e-12 47.1 0.2 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC86460.1 - 4.3e-33 112.5 2.5 1.8e-09 37.5 0.2 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86460.1 - 4.2e-32 106.9 4.8 6.6e-06 25.8 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Death PF00531.17 EMC86460.1 - 1.1e-06 28.3 0.7 3e-06 26.9 0.5 1.9 1 0 0 1 1 1 1 Death domain SRCR_2 PF15494.1 EMC86461.1 - 0.13 12.4 2.6 0.26 11.5 0.4 2.5 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain DUF641 PF04859.7 EMC86461.1 - 0.31 10.7 15.1 1.9 8.2 2.0 3.6 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EMC86461.1 - 3 7.3 8.3 7.8 6.0 0.9 2.8 2 0 0 2 2 2 0 Septum formation initiator YlqD PF11068.3 EMC86461.1 - 4.5 7.3 11.3 12 5.9 0.8 3.0 2 1 0 2 2 2 0 YlqD protein MFS_1 PF07690.11 EMC86462.1 - 2.2e-34 118.7 30.7 3.8e-24 85.0 10.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC86462.1 - 5.7e-32 110.8 19.0 5.6e-29 101.0 2.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.1 EMC86462.1 - 2.8e-12 46.2 8.7 4.7e-12 45.5 6.0 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EMC86462.1 - 8.4e-05 22.3 6.1 8.4e-05 22.3 4.2 2.3 1 1 0 2 2 2 1 Pentapeptide repeats (9 copies) DUF1228 PF06779.9 EMC86462.1 - 0.0047 16.9 1.3 0.0047 16.9 0.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) MFS_1_like PF12832.2 EMC86462.1 - 0.093 12.5 4.0 0.32 10.8 0.0 3.5 4 0 0 4 4 4 0 MFS_1 like family NOA36 PF06524.7 EMC86462.1 - 4.8 6.3 10.1 7.8 5.6 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein 7tm_1 PF00001.16 EMC86463.1 - 1.6e-39 135.5 40.5 1.3e-38 132.6 28.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRRSV_2b PF07069.6 EMC86463.1 - 0.028 14.7 0.8 0.028 14.7 0.5 3.7 4 1 1 5 5 5 0 Porcine reproductive and respiratory syndrome virus 2b 7tm_1 PF00001.16 EMC86464.1 - 1.3e-48 165.3 30.8 1.7e-48 165.0 21.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC86464.1 - 0.01 14.9 30.2 0.038 13.1 20.9 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.16 EMC86465.1 - 1.3e-45 155.5 25.1 1.3e-45 155.5 17.4 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) NB PF04159.8 EMC86465.1 - 0.21 11.3 2.0 0.59 9.8 0.3 2.4 2 1 0 2 2 2 0 NB glycoprotein S_100 PF01023.14 EMC86466.1 - 2.9e-19 68.1 0.4 4.7e-19 67.4 0.2 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 EMC86466.1 - 7.5e-07 29.1 1.2 1.3e-06 28.4 0.8 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC86466.1 - 3.6e-06 25.8 1.6 3e-05 23.0 0.4 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EMC86466.1 - 0.0018 17.9 0.7 0.18 11.7 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EMC86466.1 - 0.0081 15.4 3.0 0.062 12.6 0.5 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC86466.1 - 0.028 14.0 2.2 0.028 14.0 1.5 1.9 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.2 EMC86466.1 - 0.063 13.0 0.2 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand CRF-BP PF05428.6 EMC86467.1 - 1.3e-137 457.7 0.0 1.5e-137 457.5 0.0 1.0 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) G-patch PF01585.18 EMC86468.1 - 5.2e-15 54.9 4.4 1e-14 54.0 3.1 1.5 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 EMC86468.1 - 2e-13 50.2 0.0 5e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.2 EMC86468.1 - 2.6e-06 27.1 0.4 2.6e-06 27.1 0.2 3.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site WD40 PF00400.27 EMC86470.1 - 3.6e-22 77.3 10.0 2.7e-06 27.0 0.0 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat TBCA PF02970.11 EMC86471.1 - 3.9e-23 81.3 5.7 4.2e-23 81.2 4.0 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Phage_GP20 PF06810.6 EMC86471.1 - 0.009 15.4 1.7 0.01 15.3 1.2 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 Pkip-1 PF06878.6 EMC86471.1 - 0.017 15.0 0.8 0.021 14.7 0.6 1.2 1 0 0 1 1 1 0 Pkip-1 protein DUF3841 PF12952.2 EMC86471.1 - 0.079 12.4 0.4 0.09 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) SCAMP PF04144.8 EMC86473.1 - 5.2e-75 251.1 14.1 6.4e-75 250.8 9.8 1.1 1 0 0 1 1 1 1 SCAMP family ABC2_membrane_5 PF13346.1 EMC86473.1 - 0.7 9.1 12.8 0.96 8.6 8.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein L_HGMIC_fpl PF10242.4 EMC86474.1 - 1.8e-64 217.0 8.8 2.1e-64 216.8 6.1 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 EMC86474.1 - 6.7e-11 42.1 2.3 8.9e-11 41.7 1.4 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nucleos_tra2_C PF07662.8 EMC86474.1 - 6e-05 22.6 0.9 6e-05 22.6 0.6 1.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Claudin_3 PF06653.6 EMC86474.1 - 0.0081 15.8 5.6 0.0081 15.8 3.9 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 EMC86474.1 - 0.078 12.6 16.2 0.19 11.4 11.2 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.7 EMC86474.1 - 8.7 5.8 14.8 7.3 6.0 4.1 3.0 3 0 0 3 3 3 0 SUR7/PalI family Sulfatase PF00884.18 EMC86475.1 - 3.8e-50 170.8 0.0 6.3e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMC86475.1 - 0.0054 16.0 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EMC86475.1 - 0.0077 16.5 0.3 0.031 14.5 0.2 2.0 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 EMC86475.1 - 0.038 12.8 0.1 0.072 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1501) PT-TG PF14449.1 EMC86475.1 - 0.044 13.5 0.3 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 Pre-toxin TG DAO PF01266.19 EMC86476.1 - 1.5e-74 251.1 0.0 2e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 EMC86476.1 - 4.5e-31 107.8 0.0 7.4e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Pyr_redox_3 PF13738.1 EMC86476.1 - 3.9e-08 33.6 0.0 2.2e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC86476.1 - 4.4e-06 26.6 0.5 0.00055 19.9 0.3 2.7 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain SoxG PF04268.7 EMC86476.1 - 1.3e-05 25.0 0.0 3.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family FAD_binding_2 PF00890.19 EMC86476.1 - 0.00011 21.1 0.1 0.00025 20.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC86476.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMC86476.1 - 0.0012 17.9 0.3 0.0022 17.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMC86476.1 - 0.0021 17.1 0.2 0.0041 16.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EMC86476.1 - 0.013 15.2 0.1 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMC86476.1 - 0.015 15.7 0.2 0.035 14.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMC86476.1 - 0.031 13.1 0.1 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EMC86476.1 - 0.035 13.5 0.1 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EMC86476.1 - 0.08 11.3 0.1 0.53 8.6 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein S-methyl_trans PF02574.11 EMC86477.1 - 9e-68 228.8 0.0 1.2e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase WH2 PF02205.15 EMC86478.1 - 0.0018 17.7 0.3 0.0018 17.7 0.2 3.5 4 0 0 4 4 4 1 WH2 motif Glyco_trans_1_2 PF13524.1 EMC86478.1 - 7.5 6.8 11.6 2 8.7 0.1 4.6 3 2 2 5 5 5 0 Glycosyl transferases group 1 WH1 PF00568.18 EMC86479.1 - 4e-35 119.9 0.3 8e-35 118.9 0.2 1.5 1 0 0 1 1 1 1 WH1 domain TMF_TATA_bd PF12325.3 EMC86479.1 - 0.001 18.7 19.5 0.001 18.7 13.5 3.1 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 EMC86479.1 - 0.0022 18.0 22.5 0.004 17.2 8.4 3.4 2 1 2 4 4 4 1 Domain of unknown function (DUF4164) DUF445 PF04286.7 EMC86479.1 - 0.0027 17.2 13.8 0.0041 16.7 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Tropomyosin PF00261.15 EMC86479.1 - 0.0046 16.0 21.2 0.0046 16.0 14.7 1.9 2 0 0 2 2 2 1 Tropomyosin GAS PF13851.1 EMC86479.1 - 0.005 16.0 18.5 0.005 16.0 12.8 2.6 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 EMC86479.1 - 0.011 14.2 17.7 0.016 13.7 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.4 EMC86479.1 - 0.011 14.6 18.8 0.022 13.7 13.1 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EMC86479.1 - 0.011 15.3 11.8 0.011 15.3 8.2 2.8 2 1 1 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 EMC86479.1 - 0.019 14.1 7.3 0.53 9.4 1.1 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DMPK_coil PF08826.5 EMC86479.1 - 0.019 14.8 5.6 0.019 14.8 3.9 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like CENP-K PF11802.3 EMC86479.1 - 0.021 14.0 15.3 0.036 13.2 10.6 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Fib_alpha PF08702.5 EMC86479.1 - 0.03 14.4 15.9 0.17 11.9 5.3 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EMC86479.1 - 0.039 13.7 35.1 0.22 11.3 4.4 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Nsp1_C PF05064.8 EMC86479.1 - 0.045 13.3 23.1 0.52 9.9 7.2 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region FUSC PF04632.7 EMC86479.1 - 0.051 12.0 4.4 0.065 11.6 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.7 EMC86479.1 - 0.095 12.5 13.5 0.26 11.0 5.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EMC86479.1 - 0.16 12.2 12.0 0.35 11.1 0.7 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 EMC86479.1 - 0.19 11.2 32.7 0.16 11.4 3.2 4.7 3 2 3 6 6 6 0 Septum formation initiator DUF4140 PF13600.1 EMC86479.1 - 0.23 11.9 20.9 0.75 10.2 3.0 3.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.7 EMC86479.1 - 0.25 11.1 20.1 0.14 11.9 7.0 2.9 2 1 1 3 3 3 0 Laminin Domain II Syntaxin-6_N PF09177.6 EMC86479.1 - 0.29 11.5 16.6 0.68 10.3 3.1 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.4 EMC86479.1 - 0.72 10.0 26.4 0.25 11.4 4.4 3.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MIF4G_like_2 PF09090.6 EMC86479.1 - 0.94 8.6 14.0 1.7 7.7 9.4 1.7 1 1 0 1 1 1 0 MIF4G like TPR_MLP1_2 PF07926.7 EMC86479.1 - 0.95 9.2 31.6 4.9 6.8 3.4 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3461 PF11944.3 EMC86479.1 - 0.99 9.2 14.0 0.22 11.3 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) AAA_13 PF13166.1 EMC86479.1 - 1.2 7.4 27.0 0.14 10.5 15.2 1.8 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 EMC86479.1 - 1.4 8.7 37.8 0.062 13.1 19.1 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1465 PF07323.7 EMC86479.1 - 2.7 7.5 12.2 0.21 11.1 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF342 PF03961.8 EMC86479.1 - 2.7 6.2 20.3 18 3.5 13.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EMC86479.1 - 2.8 6.9 35.8 0.22 10.5 13.4 2.5 2 1 1 3 3 3 0 Autophagy protein Apg6 TACC PF05010.9 EMC86479.1 - 3 7.5 25.6 0.78 9.4 13.7 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) COG2 PF06148.6 EMC86479.1 - 4.4 7.1 19.4 5.7 6.8 0.2 3.5 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.3 EMC86479.1 - 4.9 4.3 30.5 0.36 8.0 7.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.15 EMC86479.1 - 5.6 6.7 34.8 0.3 10.8 4.4 4.4 2 1 2 4 4 4 0 Prefoldin subunit IFT57 PF10498.4 EMC86479.1 - 5.6 5.6 27.7 1.5 7.4 14.9 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4279 PF14106.1 EMC86479.1 - 6 6.7 7.6 8.4 6.3 0.6 3.3 2 1 1 4 4 4 0 Domain of unknown function (DUF4279) DUF2968 PF11180.3 EMC86479.1 - 6.1 6.1 27.8 5.3 6.3 3.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) ADIP PF11559.3 EMC86479.1 - 6.3 6.6 37.0 0.21 11.4 9.2 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 EMC86479.1 - 6.7 6.7 28.8 0.06 13.3 6.8 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4559 PF15112.1 EMC86479.1 - 8 5.5 23.0 1.8 7.6 9.4 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4559) PAP_assoc PF03828.14 EMC86480.1 - 2e-16 59.6 0.0 4.1e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMC86480.1 - 0.00022 21.5 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Tom37_C PF11801.3 EMC86481.1 - 6.6e-15 55.3 0.5 1.6e-09 37.8 0.0 2.4 2 1 1 3 3 3 2 Tom37 C-terminal domain GST_C_3 PF14497.1 EMC86481.1 - 4.6e-09 36.6 0.0 1.2e-08 35.2 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC86481.1 - 3.1e-07 30.2 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EMC86481.1 - 5.7e-05 23.2 0.1 0.00017 21.7 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 EMC86481.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Serinc PF03348.10 EMC86482.1 - 1.2e-140 469.0 33.1 1.3e-140 468.8 23.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3593 PF12159.3 EMC86482.1 - 8.8 6.1 9.7 1.7 8.4 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3593) Pkinase PF00069.20 EMC86483.1 - 7.1e-64 215.4 0.0 8.2e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86483.1 - 9.1e-25 87.1 0.0 1.3e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC86483.1 - 0.00038 19.5 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMC86483.1 - 0.00098 18.0 0.1 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EMC86483.1 - 0.0063 16.2 0.1 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC86483.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF2638 PF10937.3 EMC86484.1 - 0.0019 19.1 0.1 0.0022 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) CENP-H PF05837.7 EMC86485.1 - 2.7e-23 82.1 8.0 3.1e-23 81.9 5.5 1.0 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Cation_efflux PF01545.16 EMC86486.1 - 3.5e-63 213.3 8.3 3.5e-63 213.3 5.8 3.0 2 1 0 2 2 2 1 Cation efflux family DUF2946 PF11162.3 EMC86486.1 - 0.00034 20.8 2.6 0.0013 18.9 1.8 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) SH2 PF00017.19 EMC86487.1 - 1.1e-42 143.6 0.1 8.8e-22 76.7 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 EMC86487.1 - 2.4e-31 108.3 1.6 4.9e-31 107.4 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.23 EMC86487.1 - 7.7e-06 25.1 1.6 0.00052 19.3 0.1 2.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMC86487.1 - 0.00023 20.5 0.0 0.00065 19.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain DUF4201 PF13870.1 EMC86487.1 - 0.001 18.5 12.9 0.0055 16.1 1.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) SH3_9 PF14604.1 EMC86487.1 - 0.0022 17.5 0.6 0.0076 15.8 0.4 2.0 1 1 0 1 1 1 1 Variant SH3 domain Laminin_I PF06008.9 EMC86487.1 - 0.013 14.8 10.8 0.026 13.8 7.5 1.4 1 0 0 1 1 1 0 Laminin Domain I IncA PF04156.9 EMC86487.1 - 0.08 12.5 18.3 0.36 10.4 12.7 2.0 1 1 0 1 1 1 0 IncA protein DUF1338 PF07063.8 EMC86487.1 - 0.73 8.8 6.3 1.3 7.9 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1338) Rab5-bind PF09311.6 EMC86487.1 - 1.3 8.9 14.0 6 6.7 9.1 2.4 1 1 0 1 1 1 0 Rabaptin-like protein Troponin PF00992.15 EMC86487.1 - 2.9 7.9 16.9 2.8 7.9 10.6 1.8 1 1 1 2 2 2 0 Troponin V_ATPase_I PF01496.14 EMC86487.1 - 5.6 4.6 11.3 9.3 3.9 7.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family THP2 PF09432.5 EMC86487.1 - 10 6.0 13.3 26 4.6 2.3 3.3 2 1 1 3 3 3 0 Tho complex subunit THP2 DUF1908 PF08926.6 EMC86489.1 - 4.1e-143 475.2 0.5 4.1e-143 475.2 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 EMC86489.1 - 5.2e-65 219.1 0.0 1e-64 218.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86489.1 - 1.4e-27 96.3 0.0 3e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 EMC86489.1 - 5e-09 36.2 0.1 1.1e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC86489.1 - 1.6e-06 27.9 0.1 3.7e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 EMC86489.1 - 3e-05 23.1 0.0 0.00021 20.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC86489.1 - 6.3e-05 22.8 0.1 0.034 13.8 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 EMC86489.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain fn3 PF00041.16 EMC86490.1 - 2.1e-13 50.1 8.3 0.0032 17.5 0.2 5.3 4 1 0 4 4 4 4 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC86490.1 - 0.031 14.4 4.9 0.052 13.7 0.0 3.2 4 0 0 4 4 4 0 Interleukin-6 receptor alpha chain, binding RRM_6 PF14259.1 EMC86491.1 - 1.7e-14 53.5 0.0 3.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC86491.1 - 5.2e-14 51.6 0.1 9.2e-14 50.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC86491.1 - 4.5e-09 36.0 0.0 7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.2 EMC86492.1 - 9e-47 156.0 41.2 3.9e-08 32.7 1.5 9.8 5 3 6 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC86492.1 - 8.8e-42 140.6 27.6 8.5e-10 38.2 0.1 6.8 3 2 1 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EMC86492.1 - 2.3e-24 81.6 34.0 0.075 13.1 0.1 16.2 16 0 0 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 EMC86492.1 - 5.3e-15 52.9 30.6 7.3 7.2 0.0 14.7 15 0 0 15 15 15 4 Leucine rich repeat PDZ PF00595.19 EMC86492.1 - 8.4e-13 48.3 0.1 2.2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LRR_5 PF13306.1 EMC86492.1 - 1e-05 25.2 4.3 0.01 15.5 0.2 3.8 2 1 1 4 4 4 2 Leucine rich repeats (6 copies) PDZ_2 PF13180.1 EMC86492.1 - 8e-05 22.4 1.1 0.0011 18.8 0.0 3.3 3 1 0 3 3 3 1 PDZ domain LRR_6 PF13516.1 EMC86492.1 - 0.0021 17.9 28.0 4.3 7.7 0.0 10.4 11 0 0 11 11 11 1 Leucine Rich repeat Peptidase_M3 PF01432.15 EMC86493.1 - 7.3e-152 506.5 0.2 1e-151 506.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 TPR_11 PF13414.1 EMC86494.1 - 4e-30 103.2 8.4 5.1e-22 77.2 2.8 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMC86494.1 - 1.2e-28 97.5 10.8 8.1e-10 37.8 1.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC86494.1 - 6.3e-23 78.8 7.2 2.3e-06 27.0 0.7 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86494.1 - 2.7e-16 58.3 5.9 6.4e-08 32.1 0.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC86494.1 - 4e-15 54.3 1.5 0.00018 21.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86494.1 - 8.6e-12 45.3 0.2 1.5e-07 31.9 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC86494.1 - 3.3e-11 42.7 0.0 0.011 16.3 0.0 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC86494.1 - 5.7e-11 41.3 7.7 0.00018 21.0 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86494.1 - 1.4e-10 40.9 3.9 2.4e-08 33.7 0.7 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86494.1 - 2.6e-10 40.4 3.2 1.7e-06 28.2 0.2 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC86494.1 - 6.2e-09 35.5 0.4 8.9e-06 25.4 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC86494.1 - 5.2e-06 26.4 8.1 0.00064 19.8 1.8 2.3 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.7 EMC86494.1 - 6.7e-06 25.8 1.3 0.0016 18.0 0.1 3.1 2 1 1 3 3 2 1 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 EMC86494.1 - 3.8e-05 23.4 4.0 0.38 10.6 0.1 3.6 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 EMC86494.1 - 0.00014 21.0 0.2 0.92 8.8 0.0 3.4 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.1 EMC86494.1 - 0.00015 22.0 0.7 0.91 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC86494.1 - 0.0028 17.5 8.4 0.12 12.3 0.3 3.7 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EMC86494.1 - 0.0032 17.7 0.2 0.012 15.9 0.1 1.8 1 1 1 2 2 2 1 Bacterial transcriptional activator domain DUF627 PF04781.7 EMC86494.1 - 0.005 16.4 1.1 0.039 13.5 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF627) Pectate_lyase_2 PF06917.7 EMC86494.1 - 0.0057 14.9 0.1 0.0077 14.5 0.1 1.1 1 0 0 1 1 1 1 Periplasmic pectate lyase DUF3856 PF12968.2 EMC86494.1 - 0.096 12.5 1.1 13 5.6 0.7 3.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) XPC-binding PF09280.6 EMC86494.1 - 0.56 9.7 15.4 0.8 9.2 2.3 2.7 3 0 0 3 3 3 0 XPC-binding domain TPR_10 PF13374.1 EMC86494.1 - 0.6 10.1 2.2 14 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF974 PF06159.8 EMC86495.1 - 1.3e-86 290.1 0.7 1.8e-86 289.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.2 EMC86495.1 - 0.00083 18.7 0.1 0.84 8.8 0.0 3.3 3 1 0 3 3 3 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.17 EMC86495.1 - 0.0066 16.4 0.5 0.44 10.6 0.0 3.0 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain AKNA PF12443.3 EMC86496.1 - 0.63 10.0 2.7 0.79 9.7 0.7 1.8 2 0 0 2 2 2 0 AT-hook-containing transcription factor Arf PF00025.16 EMC86498.1 - 4.5e-70 234.4 0.3 1.2e-69 233.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EMC86498.1 - 8.2e-12 44.7 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC86498.1 - 3.7e-11 42.5 0.0 7.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC86498.1 - 1.7e-09 36.8 0.1 7.3e-08 31.4 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 EMC86498.1 - 4.5e-08 33.6 0.1 1.5e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EMC86498.1 - 9.8e-08 31.4 0.5 1.7e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region zf-RING_5 PF14634.1 EMC86498.1 - 2e-06 27.4 2.1 2e-06 27.4 1.4 4.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-B_box PF00643.19 EMC86498.1 - 3e-06 27.0 5.0 3e-06 27.0 3.4 3.9 4 0 0 4 4 3 2 B-box zinc finger zf-C3HC4 PF00097.20 EMC86498.1 - 0.0003 20.3 1.3 0.0003 20.3 0.9 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC86498.1 - 0.00056 19.6 4.1 0.00056 19.6 2.9 4.2 4 1 0 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EMC86498.1 - 0.00061 19.4 2.9 0.00061 19.4 2.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMC86498.1 - 0.0015 18.5 3.6 0.0015 18.5 2.5 4.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.18 EMC86498.1 - 0.0019 18.1 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-C3HC4_4 PF15227.1 EMC86498.1 - 0.022 14.6 2.9 0.022 14.6 2.0 4.1 4 0 0 4 4 3 0 zinc finger of C3HC4-type, RING Pro_isomerase PF00160.16 EMC86499.1 - 9.1e-50 168.8 0.1 1.7e-49 168.0 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EMC86499.1 - 3.1e-16 58.5 3.5 0.0045 16.8 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ADAM_spacer1 PF05986.9 EMC86500.1 - 2.5e-40 136.9 0.0 1.2e-39 134.6 0.0 2.0 2 0 0 2 2 2 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.14 EMC86500.1 - 1.7e-30 105.4 0.1 3.2e-30 104.5 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.14 EMC86500.1 - 8.7e-21 73.7 73.8 8.1e-08 32.2 4.8 6.9 7 0 0 7 7 7 5 Thrombospondin type 1 domain Reprolysin PF01421.14 EMC86500.1 - 1.5e-15 57.3 0.3 6.2e-15 55.3 0.2 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.6 EMC86500.1 - 4.9e-10 39.5 6.1 3.9e-09 36.6 4.0 2.7 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain DAGK_cat PF00781.19 EMC86500.1 - 0.053 12.9 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pro_isomerase PF00160.16 EMC86501.1 - 2.1e-43 148.1 0.0 4.3e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCHC_3 PF13917.1 EMC86502.1 - 7.2e-08 32.0 0.0 1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2072 PF09845.4 EMC86502.1 - 0.023 14.6 1.3 0.028 14.3 0.9 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) CpXC PF14353.1 EMC86502.1 - 0.025 14.5 0.5 0.029 14.3 0.3 1.1 1 0 0 1 1 1 0 CpXC protein Luteo_PO PF04662.8 EMC86502.1 - 0.095 12.1 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Luteovirus P0 protein zf-CCHC PF00098.18 EMC86502.1 - 0.19 11.7 3.3 0.28 11.2 2.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Sad1_UNC PF07738.8 EMC86503.1 - 3.8e-33 114.1 0.0 4.5e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Arf PF00025.16 EMC86504.1 - 1.7e-26 92.4 0.0 2e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMC86504.1 - 7.2e-06 24.9 0.0 7.7e-06 24.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 EMC86504.1 - 0.046 14.2 0.0 0.05 14.0 0.0 1.1 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 EMC86504.1 - 0.059 12.5 0.0 0.061 12.5 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pyrophosphatase PF00719.14 EMC86505.1 - 6.5e-56 188.1 0.5 8e-56 187.8 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase 7tm_1 PF00001.16 EMC86506.1 - 2.8e-59 200.3 16.8 2.8e-59 200.3 11.6 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86506.1 - 2.8e-09 36.5 13.5 5.6e-09 35.5 9.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_8 PF13855.1 EMC86507.1 - 2.5e-16 59.1 4.7 1.6e-08 34.1 1.8 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EMC86507.1 - 3.6e-16 58.3 3.7 2.4e-06 27.0 0.0 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC86507.1 - 6.1e-13 46.8 2.8 0.19 11.9 0.1 6.1 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EMC86507.1 - 1.2e-07 30.7 6.5 0.096 12.9 0.1 5.9 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EMC86507.1 - 5.1e-07 29.1 0.5 8.8 6.7 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 EMC86507.1 - 0.0015 18.1 0.3 0.0076 15.8 0.1 1.8 1 1 1 2 2 2 1 Leucine-rich repeat eIF_4EBP PF05456.6 EMC86508.1 - 1.1e-22 79.8 0.0 1.2e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) GRIP PF01465.15 EMC86509.1 - 1.5e-16 59.5 0.3 5.4e-16 57.8 0.2 2.1 1 0 0 1 1 1 1 GRIP domain HOOK PF05622.7 EMC86509.1 - 7.1e-05 20.8 57.9 0.00015 19.7 25.5 9.0 1 1 7 8 8 8 4 HOOK protein GAS PF13851.1 EMC86509.1 - 0.00068 18.8 17.4 0.00068 18.8 12.1 14.9 3 2 9 12 12 12 4 Growth-arrest specific micro-tubule binding Sulfotransfer_1 PF00685.22 EMC86510.1 - 1.6e-92 309.5 3.3 1.9e-92 309.3 2.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC86510.1 - 0.0072 17.2 0.0 0.012 16.5 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family SSF PF00474.12 EMC86511.1 - 3.2e-32 111.6 30.1 5e-32 111.0 20.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family 7tm_1 PF00001.16 EMC86512.1 - 2.5e-30 105.4 10.8 2.8e-30 105.3 7.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC86512.1 - 4e-06 26.1 6.0 5.3e-06 25.7 4.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv BCD PF15461.1 EMC86512.1 - 0.00041 19.8 5.0 0.001 18.5 3.5 1.7 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase TAS2R PF05296.8 EMC86512.1 - 0.00083 18.3 1.2 0.00097 18.1 0.9 1.1 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) Anoctamin PF04547.7 EMC86512.1 - 0.0022 16.7 1.0 0.0027 16.4 0.7 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel UbiA PF01040.13 EMC86512.1 - 0.058 12.6 6.4 0.084 12.0 4.4 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF2975 PF11188.3 EMC86512.1 - 0.12 12.0 3.3 0.17 11.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) zf-LITAF-like PF10601.4 EMC86512.1 - 1.2 9.0 7.2 15 5.4 0.1 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain PufQ PF05398.6 EMC86512.1 - 1.4 9.0 4.5 1.8 8.6 0.1 2.3 1 1 1 2 2 2 0 PufQ cytochrome subunit Herpes_US9 PF06072.6 EMC86512.1 - 2.2 8.1 5.1 0.39 10.5 0.4 2.0 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF1201 PF06716.6 EMC86512.1 - 2.3 8.0 11.0 0.33 10.7 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) 7tm_1 PF00001.16 EMC86513.1 - 4.8e-08 32.4 0.1 4.8e-08 32.4 0.1 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86513.1 - 3.7e-05 23.0 2.5 4.4e-05 22.7 1.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC86513.1 - 0.0038 16.3 6.1 0.0044 16.1 4.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0220 PF05255.6 EMC86513.1 - 0.011 15.0 2.0 0.012 14.9 1.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) 7TM_GPCR_Srd PF10317.4 EMC86513.1 - 0.035 13.1 5.3 0.039 12.9 3.7 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srw PF10324.4 EMC86513.1 - 0.28 10.2 4.2 0.32 10.0 2.9 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Epimerase PF01370.16 EMC86514.1 - 5.2e-47 160.2 0.0 7.7e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UXS1_N PF11803.3 EMC86514.1 - 1.1e-36 124.4 0.0 2.3e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal RmlD_sub_bind PF04321.12 EMC86514.1 - 2.2e-12 46.4 0.0 3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMC86514.1 - 1.1e-11 44.2 0.5 2e-07 30.2 0.0 2.8 2 1 0 3 3 3 2 Male sterility protein Polysacc_synt_2 PF02719.10 EMC86514.1 - 1.7e-08 33.7 0.2 0.00019 20.4 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMC86514.1 - 2e-08 33.2 0.0 1.1e-07 30.9 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMC86514.1 - 0.00019 21.4 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMC86514.1 - 0.084 12.7 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Augurin PF15187.1 EMC86515.1 - 1.8e-47 159.8 1.9 2e-47 159.7 1.3 1.0 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 SH3_9 PF14604.1 EMC86516.1 - 1.6e-42 142.8 6.4 2.4e-15 55.8 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 EMC86516.1 - 1.5e-41 139.4 12.3 5.5e-14 51.2 0.1 4.7 6 0 0 6 6 6 3 SH3 domain SH3_2 PF07653.12 EMC86516.1 - 4.2e-30 102.9 7.7 5.6e-10 38.5 0.1 4.3 4 1 1 5 5 5 3 Variant SH3 domain SH2 PF00017.19 EMC86516.1 - 4.7e-22 77.5 0.1 9.7e-22 76.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 EMC86516.1 - 4.8e-11 42.6 10.0 0.0011 19.1 0.2 3.6 3 1 0 3 3 3 3 Bacterial SH3 domain hSH3 PF14603.1 EMC86516.1 - 0.043 13.8 0.1 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain LIM PF00412.17 EMC86517.1 - 2.1e-47 158.9 71.3 4.4e-13 49.0 5.2 5.1 5 0 0 5 5 5 5 LIM domain Ureidogly_hydro PF04115.7 EMC86517.1 - 0.039 13.3 0.0 0.29 10.4 0.0 2.2 1 1 1 2 2 2 0 Ureidoglycolate hydrolase Ashwin PF15323.1 EMC86518.1 - 4.5e-84 281.7 8.9 5.2e-84 281.5 6.2 1.0 1 0 0 1 1 1 1 Developmental protein Vps39_2 PF10367.4 EMC86519.1 - 6.6e-29 100.2 0.0 1.5e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EMC86519.1 - 2.7e-26 91.6 7.1 4.3e-25 87.8 1.5 2.8 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 EMC86519.1 - 1.6e-14 53.6 14.3 1.8e-09 37.3 3.3 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.17 EMC86519.1 - 1.8e-13 50.5 0.0 5.2e-13 49.0 0.0 1.8 1 1 1 2 2 2 1 CNH domain Ribosomal_S9 PF00380.14 EMC86520.1 - 1.7e-33 115.4 0.0 3.1e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 V-set PF07686.12 EMC86521.1 - 1.1e-17 63.9 0.0 1.3e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC86521.1 - 2.1e-09 37.1 0.1 1.6e-08 34.2 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC86521.1 - 3.4e-07 30.2 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 EMC86521.1 - 9.4e-06 25.4 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Ig_3 PF13927.1 EMC86521.1 - 0.00082 19.8 0.0 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 EMC86521.1 - 0.0014 18.7 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain IGFBP PF00219.13 EMC86522.1 - 0.11 13.1 9.4 1.3 9.6 0.5 3.1 3 0 0 3 3 3 0 Insulin-like growth factor binding protein RNA_pol_Rpb1_R PF05001.8 EMC86522.1 - 2.3 8.5 36.8 2.5 8.4 2.1 5.7 4 1 1 5 5 5 0 RNA polymerase Rpb1 C-terminal repeat DUF3338 PF11819.3 EMC86523.1 - 2.7e-59 198.5 7.4 2.7e-59 198.5 5.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_M PF00373.13 EMC86523.1 - 1.7e-19 70.2 7.4 2.6e-19 69.6 0.0 3.3 3 0 0 3 3 3 1 FERM central domain FERM_C PF09380.5 EMC86523.1 - 2.3e-19 69.3 0.5 1e-18 67.2 0.4 2.2 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 EMC86523.1 - 2.2e-15 56.4 0.0 6e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain Tropomodulin PF03250.9 EMC86524.1 - 6e-17 61.5 0.7 6e-17 61.5 0.5 2.2 3 0 0 3 3 3 1 Tropomodulin Nop14 PF04147.7 EMC86524.1 - 0.00013 20.1 20.5 0.00013 20.1 14.2 1.8 2 0 0 2 2 2 1 Nop14-like family ExbD PF02472.11 EMC86524.1 - 0.0085 16.0 0.7 0.029 14.3 0.5 1.9 1 1 0 1 1 1 1 Biopolymer transport protein ExbD/TolR LRR_6 PF13516.1 EMC86524.1 - 0.21 11.7 1.9 0.35 11.0 0.1 2.4 3 0 0 3 3 3 0 Leucine Rich repeat NOA36 PF06524.7 EMC86524.1 - 0.73 9.0 18.8 1.3 8.2 13.0 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 EMC86524.1 - 1.2 8.3 29.3 0.02 14.1 14.8 1.9 2 0 0 2 2 2 0 SDA1 DNA_pol_phi PF04931.8 EMC86524.1 - 6.9 4.3 24.7 12 3.5 17.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.11 EMC86524.1 - 9.2 5.1 15.3 19 4.1 10.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ThiF PF00899.16 EMC86525.1 - 4.9e-40 136.5 0.1 2e-39 134.5 0.0 2.0 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EMC86525.1 - 1.3e-26 92.2 0.3 2.7e-26 91.1 0.2 1.6 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EMC86525.1 - 6.5e-23 80.0 0.2 1.4e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMC86525.1 - 4.2e-12 45.2 0.8 1e-11 44.0 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EMC86525.1 - 0.00012 21.5 0.0 0.00027 20.4 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EMC86525.1 - 0.00034 20.7 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 EMC86525.1 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.22 EMC86525.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TMF_TATA_bd PF12325.3 EMC86526.1 - 1.1e-36 125.1 10.8 1.1e-36 125.1 7.5 8.0 2 1 7 9 9 9 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EMC86526.1 - 2.6e-18 65.5 25.3 2.6e-18 65.5 17.5 11.9 6 4 7 13 13 13 4 TATA element modulatory factor 1 DNA binding DUF1515 PF07439.6 EMC86526.1 - 0.0013 18.4 1.9 0.0013 18.4 1.3 6.3 4 1 2 7 7 7 1 Protein of unknown function (DUF1515) SlyX PF04102.7 EMC86526.1 - 0.0058 16.9 3.6 0.0058 16.9 2.5 10.0 5 3 6 12 12 12 3 SlyX DUF563 PF04577.9 EMC86527.1 - 1.1e-24 87.4 0.4 1.8e-24 86.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TAFA PF12020.3 EMC86528.1 - 2.1e-56 187.9 11.6 2.6e-56 187.7 8.1 1.1 1 0 0 1 1 1 1 TAFA family TAFA PF12020.3 EMC86529.1 - 1.3e-52 175.8 14.6 8.1e-52 173.3 10.1 1.8 1 1 0 1 1 1 1 TAFA family ATP-grasp_2 PF08442.5 EMC86530.1 - 1.2e-70 237.0 1.0 2.1e-70 236.2 0.7 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EMC86530.1 - 1.8e-28 99.0 0.1 3.8e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EMC86530.1 - 2.7e-06 26.7 1.5 7.3e-06 25.3 0.3 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EMC86530.1 - 0.047 13.0 0.1 0.11 11.7 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.11 EMC86531.1 - 2.9e-45 154.5 34.6 2.9e-37 128.2 17.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC86531.1 - 6.9e-07 28.9 12.9 0.03 14.0 0.0 5.3 4 1 2 6 6 6 3 MFS_1 like family DUF2371 PF10177.4 EMC86531.1 - 0.038 13.8 0.1 1.1 9.0 0.0 2.9 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) IncA PF04156.9 EMC86531.1 - 6.4 6.3 0.0 6.4 6.3 0.0 3.5 4 1 0 4 4 4 0 IncA protein BACK PF07707.10 EMC86532.1 - 4.4e-31 106.7 2.0 3.1e-30 104.0 0.5 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 EMC86532.1 - 1.3e-29 101.4 13.9 3.9e-10 39.0 0.3 5.8 6 0 0 6 6 6 4 Kelch motif BTB PF00651.26 EMC86532.1 - 9.3e-29 99.6 0.3 1.9e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 EMC86532.1 - 5.1e-27 92.8 2.3 4.3e-06 26.6 0.0 5.9 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EMC86532.1 - 3.1e-13 48.9 5.2 3.9e-06 26.4 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 EMC86532.1 - 1.2e-12 47.4 0.3 0.0081 15.9 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC86532.1 - 1.4e-09 37.8 0.6 0.0063 16.6 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC86532.1 - 0.00024 20.9 1.9 22 5.1 0.0 4.5 4 0 0 4 4 4 0 Kelch motif DUF3342 PF11822.3 EMC86532.1 - 0.00097 18.3 0.1 0.004 16.3 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) LRR_8 PF13855.1 EMC86533.1 - 2.2e-79 261.1 72.6 7.3e-16 57.6 2.5 8.0 2 1 7 9 9 9 9 Leucine rich repeat I-set PF07679.11 EMC86533.1 - 2.5e-54 181.0 0.0 6.3e-22 77.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain LRR_4 PF12799.2 EMC86533.1 - 1.1e-37 127.0 48.9 1.4e-05 24.6 0.2 9.6 2 1 5 10 10 10 10 Leucine Rich repeats (2 copies) Ig_2 PF13895.1 EMC86533.1 - 5.7e-37 125.6 0.0 7.4e-12 45.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC86533.1 - 3.4e-28 97.9 0.0 3.3e-10 40.3 0.0 4.5 3 2 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.1 EMC86533.1 - 2.4e-27 95.2 0.0 4.4e-09 36.1 0.0 4.1 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC86533.1 - 7.7e-26 86.1 39.7 0.3 11.2 0.0 15.7 16 0 0 16 16 15 9 Leucine Rich Repeat ig PF00047.20 EMC86533.1 - 5.4e-21 74.4 0.0 1.5e-09 37.8 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC86533.1 - 2.5e-18 66.0 0.1 0.0002 21.2 0.0 4.0 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC86533.1 - 6.6e-11 41.9 0.1 0.00064 19.5 0.0 3.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain LRR_6 PF13516.1 EMC86533.1 - 2.2e-10 39.4 44.0 0.68 10.1 0.1 14.2 15 1 1 16 16 15 3 Leucine Rich repeat LRR_7 PF13504.1 EMC86533.1 - 1.1e-08 33.9 48.7 2.2 8.8 0.1 15.4 16 0 0 16 16 16 2 Leucine rich repeat LRR_9 PF14580.1 EMC86533.1 - 3.1e-08 33.3 8.4 0.081 12.4 0.1 5.0 1 1 4 5 5 5 4 Leucine-rich repeat LRRCT PF01463.19 EMC86533.1 - 0.014 15.6 0.0 0.064 13.5 0.0 2.2 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain C2-set PF05790.10 EMC86533.1 - 0.032 14.1 0.0 15 5.6 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Mito_carr PF00153.22 EMC86534.1 - 1.8e-54 181.4 5.5 1.5e-20 72.6 0.3 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein LRR_1 PF00560.28 EMC86535.1 - 1.2 9.4 8.3 45 4.6 0.4 4.9 3 2 0 3 3 3 0 Leucine Rich Repeat DUF2552 PF10827.3 EMC86537.1 - 0.13 12.1 9.0 43 4.1 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2552) PAPA-1 PF04795.7 EMC86538.1 - 2.4e-10 40.9 15.9 2.4e-10 40.9 11.0 1.7 2 0 0 2 2 2 1 PAPA-1-like conserved region tRNA-synt_1c PF00749.16 EMC86538.1 - 0.54 8.8 7.4 0.65 8.5 5.1 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain PHO4 PF01384.15 EMC86539.1 - 2.6e-131 437.1 2.4 3.2e-131 436.8 1.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF3855 PF12967.2 EMC86539.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) CKAP2_C PF15297.1 EMC86540.1 - 1.8e-54 184.9 3.9 7.1e-33 113.8 1.2 2.0 2 0 0 2 2 2 2 Cytoskeleton-associated protein 2 C-terminus TcdA_TcdB_pore PF12920.2 EMC86540.1 - 0.035 12.0 0.0 0.054 11.4 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain ThiS PF02597.15 EMC86540.1 - 0.041 14.3 0.0 9.1 6.7 0.0 3.4 3 0 0 3 3 3 0 ThiS family IL1 PF00340.14 EMC86541.1 - 5.7e-22 77.4 0.0 9.6e-22 76.6 0.0 1.3 1 0 0 1 1 1 1 Interleukin-1 / 18 IL1_propep PF02394.11 EMC86541.1 - 4.3e-16 59.2 0.0 7.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Interleukin-1 propeptide E1_dh PF00676.15 EMC86542.1 - 4.7e-92 307.9 0.0 5.9e-92 307.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4343 PF14243.1 EMC86542.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Pro_isomerase PF00160.16 EMC86544.1 - 3e-44 150.9 0.1 3.3e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SHIPPO-rpt PF07004.7 EMC86545.1 - 3.6e-07 30.7 32.6 0.03 15.2 0.7 6.6 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat BRICHOS PF04089.9 EMC86546.1 - 2.3e-07 30.5 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 BRICHOS domain 7tm_1 PF00001.16 EMC86548.1 - 5.6e-55 186.2 9.2 6.9e-55 185.9 6.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86548.1 - 5.8e-07 28.9 0.8 7.2e-07 28.6 0.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 EMC86548.1 - 1.1e-06 28.0 0.2 2.4e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.4 EMC86548.1 - 0.023 13.7 0.3 0.023 13.7 0.2 1.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx ATP_synt_H PF05493.8 EMC86548.1 - 0.32 11.0 3.8 2.3 8.3 2.6 2.5 1 1 0 1 1 1 0 ATP synthase subunit H BioY PF02632.9 EMC86548.1 - 4 7.0 10.1 0.061 12.9 0.5 2.5 3 0 0 3 3 3 0 BioY family SOCS PF12610.3 EMC86551.1 - 2.4e-19 69.4 2.9 6.8e-19 67.9 2.0 1.8 1 0 0 1 1 1 1 Suppressor of cytokine signalling SOCS_box PF07525.11 EMC86551.1 - 1.3e-12 47.3 0.2 3.2e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 EMC86551.1 - 3.1e-09 36.5 0.0 6.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain EF-hand_7 PF13499.1 EMC86552.1 - 4.7e-11 42.6 3.0 6.2e-11 42.2 1.8 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC86552.1 - 2.4e-08 33.1 0.3 0.0054 16.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMC86552.1 - 4.3e-07 28.7 0.2 0.00077 18.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EMC86552.1 - 0.0041 16.4 2.9 0.011 15.0 0.6 2.6 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC86552.1 - 0.0047 16.5 1.5 0.024 14.2 0.1 2.4 2 2 0 2 2 2 1 EF-hand domain pair EntA_Immun PF08951.5 EMC86552.1 - 0.6 10.2 2.6 1.1 9.4 0.5 2.0 2 0 0 2 2 2 0 Enterocin A Immunity Fibrinogen_C PF00147.13 EMC86553.1 - 2.6e-81 272.7 10.1 3.4e-81 272.3 7.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FlaC_arch PF05377.6 EMC86553.1 - 0.00032 20.5 2.8 0.0093 15.8 0.5 2.7 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) BicD PF09730.4 EMC86553.1 - 0.0017 16.8 2.9 0.0024 16.3 2.0 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Exonuc_VII_L PF02601.10 EMC86553.1 - 0.02 14.0 1.1 0.026 13.7 0.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.11 EMC86553.1 - 0.062 13.5 3.4 0.14 12.3 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 MutS_II PF05188.12 EMC86553.1 - 0.11 12.5 0.5 0.28 11.2 0.2 1.8 2 0 0 2 2 2 0 MutS domain II Prefoldin PF02996.12 EMC86553.1 - 0.12 12.0 5.6 2.4 7.8 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit Uds1 PF15456.1 EMC86553.1 - 0.33 10.9 5.3 0.71 9.8 3.7 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Laminin_II PF06009.7 EMC86553.1 - 0.43 10.3 7.8 0.21 11.3 2.6 2.0 2 0 0 2 2 2 0 Laminin Domain II PEP-utilisers_N PF05524.8 EMC86553.1 - 0.73 9.6 2.3 3 7.6 0.2 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 EMC86553.1 - 0.96 9.0 8.0 1.2 8.6 0.5 2.1 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 EMC86553.1 - 3.2 7.9 8.1 11 6.2 5.6 2.0 1 1 0 1 1 1 0 Syntaxin HR1 PF02185.11 EMC86553.1 - 7 6.4 10.2 1 9.1 2.6 2.4 2 0 0 2 2 2 0 Hr1 repeat DUF4098 PF13345.1 EMC86554.1 - 1.8e-13 50.2 29.3 2.6e-09 36.9 4.2 3.5 2 2 2 4 4 4 3 Domain of unknown function (DUF4098) DUF4097 PF13349.1 EMC86554.1 - 0.014 14.9 12.2 2.2 7.8 0.6 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4097) CBF_beta PF02312.12 EMC86554.1 - 0.045 13.3 1.0 12 5.4 0.1 2.8 2 1 0 3 3 3 0 Core binding factor beta subunit DUF2807 PF10988.3 EMC86554.1 - 0.54 9.7 8.7 0.5 9.8 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2807) LRR_6 PF13516.1 EMC86555.1 - 1.7e-26 89.2 25.7 0.053 13.6 0.1 14.8 16 0 0 16 16 16 7 Leucine Rich repeat LRR_1 PF00560.28 EMC86555.1 - 1.9e-15 54.5 25.0 1 9.6 0.0 13.4 11 4 2 13 13 13 5 Leucine Rich Repeat LRR_4 PF12799.2 EMC86555.1 - 4.4e-15 54.9 15.2 0.00066 19.2 0.0 9.2 6 2 5 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC86555.1 - 6.7e-13 48.1 16.6 3.6e-05 23.4 0.1 7.0 4 2 4 8 8 8 6 Leucine rich repeat F-box-like PF12937.2 EMC86555.1 - 1.3e-07 31.1 2.0 3.7e-07 29.7 1.4 1.9 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EMC86555.1 - 1.3e-05 24.5 28.4 2.3 8.7 0.1 11.9 14 0 0 14 14 14 2 Leucine rich repeat F-box PF00646.28 EMC86555.1 - 7.5e-05 22.2 1.3 0.00022 20.7 0.2 2.4 2 0 0 2 2 2 1 F-box domain Ste50p-SAM PF09235.5 EMC86555.1 - 0.0017 18.3 6.8 9.2 6.3 0.1 6.0 5 2 0 5 5 5 1 Ste50p, sterile alpha motif Arm_2 PF04826.8 EMC86556.1 - 3.1e-71 239.4 6.8 3.5e-71 239.3 4.7 1.0 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.18 EMC86556.1 - 2.6e-10 39.7 1.1 0.0016 18.2 0.1 3.5 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC86556.1 - 3.7e-06 27.1 0.1 0.0067 16.6 0.0 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 EMC86556.1 - 8.4e-05 22.3 0.2 0.27 11.4 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat PUL PF08324.6 EMC86556.1 - 0.0045 15.8 2.8 0.025 13.3 1.5 2.0 1 1 1 2 2 2 1 PUL domain KAP PF05804.7 EMC86556.1 - 0.025 12.5 0.2 0.036 12.0 0.2 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) HEAT_EZ PF13513.1 EMC86556.1 - 0.063 13.7 0.4 3.8 8.1 0.1 2.7 3 0 0 3 3 3 0 HEAT-like repeat Atx10homo_assoc PF09759.4 EMC86556.1 - 0.11 12.2 1.0 1.3 8.8 0.4 2.3 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.3 EMC86556.1 - 0.14 12.0 0.6 0.32 10.9 0.2 1.7 2 0 0 2 2 2 0 V-ATPase subunit H Lactamase_B_2 PF12706.2 EMC86557.1 - 8.5e-41 139.6 0.1 1.2e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC86557.1 - 5.8e-14 52.1 0.0 9.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC86557.1 - 0.00082 19.0 1.0 0.036 13.7 0.5 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Myb_DNA-binding PF00249.26 EMC86558.1 - 1.4e-17 63.4 0.2 4.3e-10 39.4 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.26 EMC86558.1 - 7.4e-17 60.8 0.1 7.4e-17 60.8 0.1 2.8 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.1 EMC86558.1 - 1.3e-09 38.0 6.1 6.6e-06 26.1 0.1 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain AAA PF00004.24 EMC86559.1 - 5.9e-41 139.7 0.0 2.5e-40 137.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC86559.1 - 6.4e-06 26.3 0.0 0.0007 19.7 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMC86559.1 - 0.00015 21.4 0.1 0.0011 18.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC86559.1 - 0.0016 18.4 0.0 0.0081 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMC86559.1 - 0.0017 19.1 0.1 0.0053 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMC86559.1 - 0.0029 17.5 0.0 0.0092 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMC86559.1 - 0.0044 15.9 0.0 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMC86559.1 - 0.0054 16.4 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EMC86559.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMC86559.1 - 0.0095 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMC86559.1 - 0.0096 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 EMC86559.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMC86559.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EMC86559.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EMC86559.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMC86559.1 - 0.037 14.3 0.1 0.085 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EMC86559.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EMC86559.1 - 0.065 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EMC86559.1 - 0.074 13.2 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.1 EMC86559.1 - 0.078 12.3 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EMC86559.1 - 0.09 12.3 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMC86559.1 - 0.14 11.6 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sulfate_transp PF00916.15 EMC86560.1 - 3.1e-71 239.6 17.5 5.4e-71 238.8 11.6 1.8 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMC86560.1 - 2.9e-30 103.7 3.7 2.9e-30 103.7 2.5 3.4 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMC86560.1 - 8.5e-27 92.8 0.1 1.6e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain ORC5_C PF14630.1 EMC86561.1 - 4.1e-86 288.8 0.1 6.7e-86 288.0 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EMC86561.1 - 2.9e-11 43.6 0.0 6.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC86561.1 - 2.9e-09 37.1 0.1 1.2e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EMC86561.1 - 0.00089 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase Kinesin PF00225.18 EMC86561.1 - 0.0017 17.1 0.6 0.0052 15.5 0.3 1.7 1 1 1 2 2 2 1 Kinesin motor domain AAA_14 PF13173.1 EMC86561.1 - 0.0047 16.8 0.6 0.14 12.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 EMC86561.1 - 0.041 12.8 0.0 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.24 EMC86561.1 - 0.076 13.2 0.0 0.24 11.6 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC86561.1 - 0.11 13.3 0.0 0.28 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMC86561.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EMC86561.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase PF00069.20 EMC86563.1 - 1.8e-34 119.0 6.7 1.2e-22 80.2 0.3 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86563.1 - 2.9e-13 49.4 0.1 1e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase TruD PF01142.13 EMC86564.1 - 6.9e-68 229.0 0.0 1.1e-65 221.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) R3H PF01424.17 EMC86564.1 - 0.036 13.7 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 R3H domain XPG_I_2 PF12813.2 EMC86564.1 - 0.067 12.6 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing RINT1_TIP1 PF04437.8 EMC86565.1 - 8e-159 529.3 10.2 8e-159 529.3 7.1 2.1 2 0 0 2 2 2 2 RINT-1 / TIP-1 family DUF3886 PF13025.1 EMC86565.1 - 6.1 6.8 9.5 8.8 6.3 4.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) EF-hand_6 PF13405.1 EMC86566.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EMC86566.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain pair SCA7 PF08313.7 EMC86567.1 - 5.7e-28 96.3 4.9 6.4e-28 96.1 2.4 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF3505 PF12013.3 EMC86567.1 - 0.08 13.1 1.9 0.32 11.2 1.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) MARVEL PF01284.18 EMC86568.1 - 2.2e-35 121.5 14.0 2.8e-35 121.2 9.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4418 PF14387.1 EMC86568.1 - 0.047 13.4 2.5 0.082 12.6 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) NAPRTase PF04095.11 EMC86569.1 - 4.3e-80 268.5 0.0 5.9e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family PI3Ka PF00613.15 EMC86570.1 - 5.5e-63 211.4 1.5 5.5e-63 211.4 1.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EMC86570.1 - 5.6e-54 183.1 0.3 1.1e-53 182.1 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EMC86570.1 - 3.3e-28 98.2 0.4 9.1e-28 96.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 EMC86570.1 - 1.5e-27 95.6 5.7 2.2e-26 91.8 0.0 3.6 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain BMFP PF04380.8 EMC86570.1 - 0.047 13.8 0.8 1.1 9.5 0.0 3.1 3 0 0 3 3 3 0 Membrane fusogenic activity COX5A PF02284.11 EMC86570.1 - 0.081 12.8 0.2 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va cNMP_binding PF00027.24 EMC86571.1 - 1.5e-42 143.2 0.1 1.1e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF627 PF04781.7 EMC86571.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF627) AXH PF08517.7 EMC86572.1 - 1.7e-43 147.3 0.0 3.4e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) HMG_box PF00505.14 EMC86572.1 - 9.6e-15 54.6 0.8 1.8e-14 53.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC86572.1 - 4.5e-09 36.5 2.0 9.3e-09 35.5 1.4 1.5 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EMC86572.1 - 0.014 14.7 0.4 0.024 13.9 0.3 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 COG5 PF10392.4 EMC86573.1 - 2.8e-31 108.2 2.2 2.8e-31 108.2 1.6 2.9 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.6 EMC86573.1 - 5.6e-09 35.7 4.1 6.2e-09 35.5 0.1 3.3 4 1 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.6 EMC86573.1 - 0.00077 19.3 0.5 0.00077 19.3 0.4 4.0 4 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 EMC86573.1 - 0.076 11.9 7.3 0.029 13.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) 7tm_1 PF00001.16 EMC86574.1 - 1.1e-25 90.2 20.3 1.7e-25 89.6 14.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.6 EMC86574.1 - 5.6 5.6 13.9 0.86 8.3 6.4 2.1 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Dus PF01207.12 EMC86575.1 - 2.1e-73 246.8 0.2 2.5e-73 246.5 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EMC86575.1 - 4.9e-07 29.2 0.4 0.0012 18.1 0.0 1.5 1 1 1 2 2 2 2 Histidine biosynthesis protein Oxidored_FMN PF00724.15 EMC86575.1 - 2.9e-05 23.2 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.12 EMC86575.1 - 0.004 16.3 0.0 0.0076 15.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI ThiG PF05690.9 EMC86575.1 - 0.048 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Imm33 PF15580.1 EMC86575.1 - 0.14 11.6 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 33 Bap31 PF05529.7 EMC86576.1 - 1.6e-41 141.8 4.0 2.2e-41 141.4 2.8 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like HALZ PF02183.13 EMC86576.1 - 0.0012 18.5 11.0 0.11 12.2 0.1 3.2 3 0 0 3 3 3 2 Homeobox associated leucine zipper MscS_porin PF12795.2 EMC86576.1 - 0.0031 16.8 6.0 0.0031 16.8 4.2 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain AATF-Che1 PF13339.1 EMC86576.1 - 0.013 15.6 6.6 0.013 15.6 4.5 1.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor ADIP PF11559.3 EMC86576.1 - 0.019 14.8 12.3 0.041 13.7 8.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding PspA_IM30 PF04012.7 EMC86576.1 - 0.02 14.2 14.1 0.034 13.4 9.7 1.3 1 0 0 1 1 1 0 PspA/IM30 family DUF948 PF06103.6 EMC86576.1 - 0.035 13.9 9.7 1.1 9.2 0.1 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HOOK PF05622.7 EMC86576.1 - 0.043 11.6 13.8 0.033 12.0 8.1 1.7 2 0 0 2 2 2 0 HOOK protein APG6 PF04111.7 EMC86576.1 - 0.047 12.7 18.2 0.15 11.1 12.6 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EMC86576.1 - 0.2 10.8 19.2 0.03 13.5 10.0 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cluap1 PF10234.4 EMC86576.1 - 0.23 10.6 9.6 0.41 9.7 6.7 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3450 PF11932.3 EMC86576.1 - 0.58 9.3 9.5 0.27 10.4 4.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.1 EMC86576.1 - 0.8 9.7 10.2 0.47 10.5 3.5 2.4 2 1 1 3 3 3 0 Syntaxin-like protein DUF724 PF05266.9 EMC86576.1 - 0.85 9.2 13.2 4.4 6.8 9.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.4 EMC86576.1 - 0.91 8.4 9.5 1.5 7.7 6.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 EMC86576.1 - 1.1 8.6 11.4 0.24 10.7 5.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF1664 PF07889.7 EMC86576.1 - 3.5 7.4 10.1 0.54 10.0 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 EMC86576.1 - 5.1 7.1 8.1 12 5.9 2.3 3.2 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Cep57_CLD_2 PF14197.1 EMC86576.1 - 7 6.6 11.8 37 4.3 0.3 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 EMC86576.1 - 8.2 6.8 17.6 4.2 7.7 2.6 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF972) Presenilin PF01080.12 EMC86576.1 - 8.3 5.1 15.3 32 3.1 10.6 1.7 1 1 0 1 1 1 0 Presenilin UPF0449 PF15136.1 EMC86576.1 - 8.4 6.6 10.9 0.59 10.3 1.6 2.8 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 Occludin_ELL PF07303.8 EMC86576.1 - 9.1 7.0 11.6 3.1 8.5 2.4 2.8 2 1 1 3 3 3 0 Occludin homology domain DivIVA PF05103.8 EMC86576.1 - 9.4 6.3 16.6 0.78 9.7 8.1 1.7 2 0 0 2 2 2 0 DivIVA protein Sulfate_transp PF00916.15 EMC86577.1 - 1.2e-66 224.6 12.8 2.2e-66 223.7 8.8 1.5 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EMC86577.1 - 3.8e-33 113.3 0.4 8.4e-33 112.2 0.3 1.6 1 0 0 1 1 1 1 STAS domain Sulfate_tra_GLY PF13792.1 EMC86577.1 - 1.7e-18 66.0 6.1 1.7e-18 66.0 4.2 3.7 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif MIG-14_Wnt-bd PF06664.7 EMC86577.1 - 0.096 11.4 5.1 0.17 10.6 3.4 1.5 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion 7tm_6 PF02949.15 EMC86577.1 - 0.2 10.4 2.4 4.6 6.0 0.1 2.5 2 0 0 2 2 2 0 7tm Odorant receptor zf-C3HC4_3 PF13920.1 EMC86578.1 - 0.00025 20.6 7.5 0.00055 19.5 5.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC86578.1 - 0.00069 19.5 9.3 0.0017 18.2 6.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC86578.1 - 0.0011 18.6 8.7 0.0022 17.5 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC86578.1 - 0.0019 17.9 7.8 0.0039 16.8 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC86578.1 - 0.03 14.1 7.9 0.07 12.9 5.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 EMC86578.1 - 0.046 13.2 6.6 0.11 12.0 4.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 EMC86578.1 - 0.048 13.4 7.3 0.18 11.6 5.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 EMC86578.1 - 1.5 8.5 8.2 3.9 7.1 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_4 PF07975.7 EMC86578.1 - 5.4 7.1 11.5 5.3 7.1 6.4 2.3 2 1 0 2 2 2 0 TFIIH C1-like domain Sulfate_transp PF00916.15 EMC86579.1 - 4.7e-71 239.0 11.1 9e-71 238.1 7.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EMC86579.1 - 2.1e-33 114.2 0.1 3.7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain Sulfate_tra_GLY PF13792.1 EMC86579.1 - 5.6e-29 99.6 3.4 5.6e-29 99.6 2.3 3.0 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif Pyr_redox_2 PF07992.9 EMC86580.1 - 7.7e-41 140.1 8.7 2.9e-40 138.3 6.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMC86580.1 - 1.2e-40 137.9 0.2 1.2e-40 137.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMC86580.1 - 2.9e-19 69.2 6.0 3e-17 62.8 1.0 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMC86580.1 - 1.4e-10 41.6 0.6 6.4e-05 23.1 0.6 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMC86580.1 - 3.8e-09 36.1 0.2 3.8e-09 36.1 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMC86580.1 - 4.1e-09 35.7 4.6 3.5e-07 29.4 0.4 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EMC86580.1 - 2e-07 30.9 2.1 0.0002 21.3 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EMC86580.1 - 1.8e-06 27.0 10.6 4.1e-06 25.9 3.2 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EMC86580.1 - 6.4e-05 22.1 0.9 0.00027 20.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EMC86580.1 - 9.9e-05 21.5 4.4 0.012 14.6 0.1 3.3 3 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EMC86580.1 - 0.00022 19.8 11.8 0.0012 17.4 0.3 3.7 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EMC86580.1 - 0.0004 19.4 1.6 0.46 9.3 0.1 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMC86580.1 - 0.00071 18.5 9.3 0.1 11.5 0.1 3.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMC86580.1 - 0.0012 18.3 4.3 0.08 12.5 0.2 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Glycos_transf_1 PF00534.15 EMC86580.1 - 0.0032 16.8 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 3HCDH_N PF02737.13 EMC86580.1 - 0.037 13.6 5.7 0.5 10.0 0.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMC86580.1 - 0.048 13.0 6.3 1.1 8.6 0.2 3.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UPF0227 PF05728.7 EMC86580.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GFO_IDH_MocA PF01408.17 EMC86580.1 - 0.35 11.3 2.4 65 4.0 0.1 3.4 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EMC86580.1 - 2.9 6.9 5.7 2.6 7.1 0.1 3.1 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Laminin_EGF PF00053.19 EMC86581.1 - 9.4e-122 396.8 237.7 4e-14 52.2 3.9 13.7 11 2 2 13 13 13 13 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 EMC86581.1 - 1.6e-83 279.3 0.1 4.4e-83 277.8 0.0 1.8 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) COPIIcoated_ERV PF07970.7 EMC86582.1 - 5.8e-47 160.1 0.3 8.5e-47 159.6 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMC86582.1 - 5.4e-20 71.1 0.3 1.3e-19 69.9 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 EMC86583.1 - 1.9e-44 151.7 0.0 5.1e-44 150.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86583.1 - 2.8e-40 138.0 0.0 7.1e-40 136.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.1 EMC86583.1 - 2.8e-26 91.0 39.4 8.5e-08 31.8 4.5 6.1 3 2 3 6 6 6 6 Leucine rich repeat Miro PF08477.8 EMC86583.1 - 5e-26 91.5 0.0 1.5e-25 90.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein LRR_4 PF12799.2 EMC86583.1 - 2e-24 84.7 45.2 1.1e-08 34.4 0.4 8.3 3 2 2 7 7 7 7 Leucine Rich repeats (2 copies) Ras PF00071.17 EMC86583.1 - 5.8e-15 55.0 0.0 1.7e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Ras family LRR_1 PF00560.28 EMC86583.1 - 1.7e-08 33.3 46.9 0.38 10.9 0.0 12.7 13 0 0 13 13 11 2 Leucine Rich Repeat Arf PF00025.16 EMC86583.1 - 2.4e-07 30.1 0.8 5.9e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Ank_2 PF12796.2 EMC86583.1 - 3.3e-05 24.1 4.2 0.0017 18.6 0.2 3.1 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) LRR_7 PF13504.1 EMC86583.1 - 0.00024 20.8 36.5 1.7 9.2 0.1 11.4 12 0 0 12 12 8 1 Leucine rich repeat Gtr1_RagA PF04670.7 EMC86583.1 - 0.00036 19.7 0.0 0.00097 18.3 0.0 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region T2SE PF00437.15 EMC86583.1 - 0.0023 16.8 0.0 0.0071 15.2 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Arm PF00514.18 EMC86583.1 - 0.0025 17.5 2.6 0.18 11.6 0.1 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat AAA_17 PF13207.1 EMC86583.1 - 0.0033 18.2 0.1 0.023 15.5 0.0 2.7 2 0 0 2 2 1 1 AAA domain Ank PF00023.25 EMC86583.1 - 0.0033 17.1 0.2 17 5.4 0.0 4.2 3 0 0 3 3 3 0 Ankyrin repeat PduV-EutP PF10662.4 EMC86583.1 - 0.0065 15.9 0.5 0.018 14.5 0.3 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EMC86583.1 - 0.0091 16.1 0.0 0.048 13.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 EMC86583.1 - 0.01 15.7 0.0 0.034 14.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EMC86583.1 - 0.011 16.0 0.2 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.4 EMC86583.1 - 0.018 13.6 0.1 0.042 12.4 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EMC86583.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 EMC86583.1 - 0.019 14.6 0.2 0.052 13.2 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LRR_6 PF13516.1 EMC86583.1 - 0.023 14.7 44.7 3.2 8.1 0.4 12.4 9 3 3 12 12 12 0 Leucine Rich repeat AAA_23 PF13476.1 EMC86583.1 - 0.032 14.5 2.9 0.66 10.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EMC86583.1 - 0.033 13.8 2.0 0.053 13.1 0.3 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EMC86583.1 - 0.051 13.8 0.0 0.23 11.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain Kdo PF06293.9 EMC86583.1 - 0.074 12.1 0.1 0.17 10.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_29 PF13555.1 EMC86583.1 - 0.081 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EMC86583.1 - 0.12 12.2 0.1 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMC86583.1 - 0.2 11.0 0.1 0.6 9.4 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain PQQ_2 PF13360.1 EMC86583.1 - 0.32 10.4 0.0 0.59 9.5 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain Sugar_tr PF00083.19 EMC86584.1 - 7.6e-91 304.9 15.0 1.9e-67 227.8 1.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC86584.1 - 6.1e-15 54.7 24.7 1.8e-07 30.2 1.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EMC86584.1 - 0.00033 19.1 1.0 0.00033 19.1 0.7 2.0 2 1 0 2 2 2 1 MFS/sugar transport protein Ral PF11058.3 EMC86584.1 - 0.098 12.0 1.1 0.19 11.1 0.7 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral DUF4552 PF15089.1 EMC86585.1 - 8.9e-10 38.0 0.9 0.00031 19.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4552) Copine PF07002.11 EMC86586.1 - 4.7e-60 201.5 0.1 7.5e-60 200.9 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 EMC86586.1 - 2.7e-29 100.8 0.5 2.4e-15 56.1 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EMC86586.1 - 1.1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DIE2_ALG10 PF04922.7 EMC86587.1 - 5.7e-136 453.4 30.7 7e-136 453.1 21.3 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family CGI-121 PF08617.5 EMC86588.1 - 1.4e-41 141.8 0.6 1.6e-41 141.6 0.4 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 RBD PF02196.10 EMC86588.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Raf-like Ras-binding domain TrmB PF01978.14 EMC86588.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB GTSE1_N PF15259.1 EMC86589.1 - 3.3e-47 159.9 1.5 7.1e-47 158.8 1.0 1.6 1 0 0 1 1 1 1 G-2 and S-phase expressed 1 K167R PF08065.7 EMC86589.1 - 0.0078 16.3 0.6 0.0078 16.3 0.4 1.7 2 0 0 2 2 2 1 K167R (NUC007) repeat KKLCAg1 PF15204.1 EMC86590.1 - 0.12 12.4 3.3 0.5 10.4 1.8 2.3 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 tRNA_Me_trans PF03054.11 EMC86591.1 - 2.5e-126 421.0 0.0 3e-126 420.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Histone PF00125.19 EMC86592.1 - 4.8e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86592.1 - 1.1e-06 28.5 0.7 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC86592.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A GRAM PF02893.15 EMC86593.1 - 3.5e-16 58.4 0.1 6.5e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.5 EMC86593.1 - 0.00014 21.3 0.1 0.00034 20.1 0.1 1.6 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Tmemb_cc2 PF10267.4 EMC86593.1 - 0.00079 18.1 2.0 0.0027 16.3 1.7 1.6 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein NUDE_C PF04880.8 EMC86593.1 - 0.015 15.6 3.9 0.034 14.4 2.6 1.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Ank PF00023.25 EMC86594.1 - 1.3e-21 75.2 0.9 6.8e-10 38.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EMC86594.1 - 2.2e-19 68.9 1.1 2.9e-11 43.2 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 EMC86594.1 - 2e-18 66.4 0.0 2.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EMC86594.1 - 7e-17 61.5 0.1 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC86594.1 - 7.5e-17 61.3 0.9 1.6e-12 47.5 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86594.1 - 2.8e-13 48.6 0.1 1.2e-06 28.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.20 EMC86594.1 - 4.9e-11 42.2 0.0 7.7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cu-oxidase_3 PF07732.10 EMC86595.1 - 0.98 9.1 3.5 17 5.1 0.0 3.5 4 0 0 4 4 4 0 Multicopper oxidase Guanylate_cyc PF00211.15 EMC86598.1 - 2.6e-114 378.9 0.4 2.3e-60 203.0 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Dynamin_N PF00350.18 EMC86600.1 - 2.3e-18 66.6 0.0 5.9e-17 61.9 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EMC86600.1 - 6.3e-11 42.2 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC86600.1 - 0.02 14.0 0.0 0.17 11.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Miro PF08477.8 EMC86600.1 - 0.031 14.7 0.0 0.65 10.5 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 EMC86600.1 - 0.038 13.4 0.0 0.08 12.3 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HLH PF00010.21 EMC86601.1 - 3.2e-12 45.9 0.0 3.7e-11 42.5 0.0 2.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Lzipper-MIP1 PF14389.1 EMC86601.1 - 0.66 10.1 21.9 0.041 13.9 4.1 3.8 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 CEP19 PF14933.1 EMC86601.1 - 4 7.7 11.6 0.21 11.9 2.7 2.4 3 0 0 3 3 3 0 CEP19-like protein zf-H2C2_2 PF13465.1 EMC86602.1 - 1.8e-15 56.3 34.6 3.9e-08 33.1 1.4 4.8 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC86602.1 - 1e-10 41.2 32.4 5.3e-05 23.3 2.3 4.9 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC86602.1 - 3.8e-07 29.9 18.3 0.014 15.7 0.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC86602.1 - 0.00071 19.3 0.3 0.00071 19.3 0.2 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 EMC86602.1 - 0.0043 17.1 11.3 0.017 15.2 0.8 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC86602.1 - 0.1 12.7 8.7 1.2 9.2 0.6 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMC86602.1 - 0.2 11.8 13.7 0.2 11.8 0.4 3.8 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding Pam16 PF03656.8 EMC86603.1 - 1.2e-41 141.5 1.5 1.3e-41 141.3 1.1 1.0 1 0 0 1 1 1 1 Pam16 DUF848 PF05852.6 EMC86603.1 - 0.042 13.6 0.5 0.045 13.6 0.3 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1900 PF08954.6 EMC86604.1 - 1.1e-80 267.7 0.0 2.8e-49 166.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1900) WD40 PF00400.27 EMC86604.1 - 9.3e-39 129.9 5.7 5.2e-09 35.6 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF1899 PF08953.6 EMC86604.1 - 0.021 14.4 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) LRR_6 PF13516.1 EMC86605.1 - 1.2e-41 136.0 41.8 0.0038 17.1 0.3 15.7 15 0 0 15 15 15 12 Leucine Rich repeat NACHT PF05729.7 EMC86605.1 - 5.7e-29 100.9 0.0 1.2e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain LRR_4 PF12799.2 EMC86605.1 - 2.4e-18 65.3 28.9 0.0048 16.4 0.0 9.5 3 3 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC86605.1 - 5.6e-13 48.4 31.6 2.2e-05 24.0 0.1 7.6 2 2 5 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EMC86605.1 - 1.5e-09 36.5 18.3 5.1 7.5 0.0 12.5 12 2 2 14 14 14 2 Leucine Rich Repeat FISNA PF14484.1 EMC86605.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Fish-specific NACHT associated domain LRR_7 PF13504.1 EMC86605.1 - 0.033 14.3 24.3 45 4.8 0.0 11.0 13 0 0 13 13 13 0 Leucine rich repeat ABC_tran PF00005.22 EMC86605.1 - 0.052 13.8 6.8 1.5 9.0 0.0 4.4 4 0 0 4 4 4 0 ABC transporter Cluap1 PF10234.4 EMC86606.1 - 5.9e-118 392.8 11.4 8.3e-118 392.4 7.9 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.7 EMC86606.1 - 0.12 11.7 3.5 0.11 11.7 1.1 1.9 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family 7tm_2 PF00002.19 EMC86607.1 - 1.6e-39 135.4 11.3 3.5e-39 134.3 7.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EMC86607.1 - 0.18 10.6 7.8 0.26 10.1 5.4 1.5 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Ank_2 PF12796.2 EMC86608.1 - 1.9e-22 79.4 0.6 3.5e-15 56.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86608.1 - 4.7e-17 60.8 1.5 3.3e-07 29.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC86608.1 - 2e-14 53.6 0.1 5.9e-09 36.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SAM_2 PF07647.12 EMC86608.1 - 9.4e-13 47.8 0.0 2e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC86608.1 - 1.7e-12 47.2 0.0 3.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.1 EMC86608.1 - 2.9e-12 45.5 0.2 0.00011 22.1 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMC86608.1 - 1.1e-10 41.3 0.8 4.2e-06 26.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) YlqD PF11068.3 EMC86608.1 - 0.095 12.7 5.2 0.21 11.6 3.6 1.5 1 0 0 1 1 1 0 YlqD protein Syntaxin-6_N PF09177.6 EMC86609.1 - 0.015 15.6 0.9 0.04 14.3 0.6 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SIT PF15330.1 EMC86609.1 - 0.24 11.5 4.5 0.078 13.1 1.1 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT NDK PF00334.14 EMC86612.1 - 2.2e-18 66.3 0.0 3.6e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pkinase PF00069.20 EMC86613.1 - 1.4e-36 125.9 0.0 1.6e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86613.1 - 2.6e-20 72.6 0.0 2.8e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC86613.1 - 1.1e-08 34.3 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC86613.1 - 0.00076 18.6 0.0 0.00095 18.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EMC86613.1 - 0.0026 16.6 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EMC86613.1 - 0.035 13.8 0.1 0.058 13.1 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Xpo1 PF08389.7 EMC86614.1 - 2.5e-27 95.6 18.9 4.4e-27 94.8 0.1 6.3 5 3 0 6 6 6 2 Exportin 1-like protein NDK PF00334.14 EMC86615.1 - 5.3e-55 184.8 0.0 6.3e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase adh_short_C2 PF13561.1 EMC86616.1 - 1.6e-28 100.1 0.0 2e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC86616.1 - 1.8e-17 63.7 0.1 2.3e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC86616.1 - 0.0011 18.6 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 KR domain RBD-FIP PF09457.5 EMC86617.1 - 7.1e-17 60.9 1.0 7.1e-17 60.9 0.7 6.2 6 2 1 7 7 7 1 FIP domain EF-hand_7 PF13499.1 EMC86617.1 - 6.8e-07 29.3 0.1 7.4e-06 26.0 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC86617.1 - 0.00054 19.0 0.1 2 7.8 0.0 3.4 3 0 0 3 3 3 2 EF hand HALZ PF02183.13 EMC86617.1 - 0.00099 18.7 10.8 0.0023 17.6 2.9 5.4 4 1 1 5 5 5 2 Homeobox associated leucine zipper Macoilin PF09726.4 EMC86617.1 - 0.0017 16.7 29.5 0.0027 16.0 20.4 1.3 1 0 0 1 1 1 1 Transmembrane protein DivIC PF04977.10 EMC86617.1 - 0.0046 16.4 3.5 0.0046 16.4 2.5 6.2 3 1 2 6 6 6 1 Septum formation initiator EF-hand_8 PF13833.1 EMC86617.1 - 0.0053 16.3 0.2 0.086 12.4 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.1 EMC86617.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_6 PF13405.1 EMC86617.1 - 0.1 12.5 0.3 34 4.7 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain Tubulin_3 PF14881.1 EMC86617.1 - 0.15 11.4 0.1 0.15 11.4 0.0 3.2 3 1 1 4 4 4 0 Tubulin domain WD40_alt PF14077.1 EMC86617.1 - 0.4 10.3 9.3 0.075 12.6 0.3 3.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF904 PF06005.7 EMC86617.1 - 0.48 10.7 59.4 0.21 11.8 4.6 5.1 1 1 2 4 4 4 0 Protein of unknown function (DUF904) HOOK PF05622.7 EMC86617.1 - 5.8 4.5 50.3 1.5e+02 -0.1 34.8 2.0 1 1 0 1 1 1 0 HOOK protein ATG16 PF08614.6 EMC86617.1 - 8.3 6.1 53.8 0.32 10.7 10.8 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Septin PF00735.13 EMC86618.1 - 5.4e-111 370.1 0.2 6.2e-111 369.9 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMC86618.1 - 2.2e-08 34.0 0.1 3.9e-08 33.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC86618.1 - 3.8e-06 26.1 0.1 7.1e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMC86618.1 - 1.5e-05 24.2 0.1 2.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 EMC86618.1 - 0.00031 20.2 0.1 0.00065 19.2 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EMC86618.1 - 0.00089 19.1 2.2 0.085 12.6 0.5 2.3 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 EMC86618.1 - 0.0012 19.3 0.3 0.0026 18.2 0.2 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC86618.1 - 0.0012 18.2 0.3 0.15 11.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EMC86618.1 - 0.0031 17.0 0.1 0.0056 16.1 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain Ras PF00071.17 EMC86618.1 - 0.0031 16.9 0.1 0.0066 15.8 0.1 1.6 1 0 0 1 1 1 1 Ras family IIGP PF05049.8 EMC86618.1 - 0.0032 16.3 0.5 0.055 12.2 0.0 2.5 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 EMC86618.1 - 0.0034 16.5 0.5 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EMC86618.1 - 0.0053 17.0 0.7 0.016 15.4 0.5 1.9 1 1 0 1 1 1 1 ABC transporter AAA_32 PF13654.1 EMC86618.1 - 0.0066 15.1 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC86618.1 - 0.0088 16.1 0.2 0.036 14.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC86618.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 EMC86618.1 - 0.024 14.1 0.3 0.12 11.7 0.1 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 EMC86618.1 - 0.035 13.6 0.1 0.065 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EMC86618.1 - 0.073 12.6 0.1 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EMC86618.1 - 0.074 12.9 0.1 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC86618.1 - 0.078 13.1 0.2 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 EMC86618.1 - 0.1 11.7 0.1 8.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MARVEL PF01284.18 EMC86619.1 - 1.3e-17 63.9 39.2 4.3e-10 39.5 7.9 2.1 2 0 0 2 2 2 2 Membrane-associating domain IP_trans PF02121.13 EMC86620.1 - 1.5e-67 227.4 0.1 1.8e-67 227.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein zf-MYND PF01753.13 EMC86621.1 - 9.9e-12 44.5 9.4 9.9e-12 44.5 6.5 1.8 2 0 0 2 2 2 1 MYND finger TPR_11 PF13414.1 EMC86622.1 - 4.5e-17 61.4 14.2 2.8e-08 33.2 1.0 4.3 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EMC86622.1 - 4.8e-15 54.1 19.5 7.9e-05 22.2 0.0 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 EMC86622.1 - 1.5e-13 49.7 28.4 5e-06 25.8 0.1 7.3 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMC86622.1 - 7.8e-12 44.0 18.9 0.0002 20.8 0.1 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC86622.1 - 1.3e-09 37.8 4.3 0.016 15.7 0.1 5.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86622.1 - 9.7e-09 35.0 20.5 6.2e-05 22.8 0.7 5.3 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86622.1 - 2.6e-06 27.2 3.7 0.085 13.0 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86622.1 - 2.3e-05 24.6 11.1 0.06 13.7 0.1 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86622.1 - 0.0011 19.5 12.4 0.89 10.3 0.1 5.5 4 2 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC86622.1 - 0.0022 18.0 1.8 0.0022 18.0 1.2 4.2 4 1 2 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMC86622.1 - 0.0044 16.7 16.8 0.071 12.9 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC86622.1 - 0.02 14.7 5.3 0.61 9.9 0.0 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Tir_receptor_N PF07490.6 EMC86622.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus TPR_6 PF13174.1 EMC86622.1 - 2.1 8.9 11.4 15 6.3 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 EMC86623.1 - 1.7e-61 202.0 55.4 1.6e-08 34.0 0.4 20.4 20 2 0 20 20 20 15 WD domain, G-beta repeat DUF667 PF05018.8 EMC86623.1 - 0.00023 20.4 0.0 0.00045 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Nucleoporin_N PF08801.6 EMC86623.1 - 0.00058 18.7 2.0 0.97 8.1 0.0 5.0 5 2 1 6 6 6 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 EMC86623.1 - 0.024 13.4 0.0 0.07 11.9 0.0 1.7 2 0 0 2 2 2 0 Coatomer WD associated region BBS2_Mid PF14783.1 EMC86623.1 - 0.032 13.9 0.0 8.3 6.2 0.0 4.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EMC86623.1 - 0.061 12.7 1.1 4.5 6.6 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain EF_assoc_2 PF08356.7 EMC86624.1 - 2.2e-35 120.2 0.0 6.1e-35 118.8 0.0 1.8 2 0 0 2 2 2 1 EF hand associated Miro PF08477.8 EMC86624.1 - 4e-31 107.9 0.0 3.5e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EMC86624.1 - 4.6e-27 93.1 0.5 2e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 EMC86624.1 - 1.7e-21 76.2 0.0 1.2e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 Ras family EF-hand_6 PF13405.1 EMC86624.1 - 7.6e-07 28.4 0.2 0.00011 21.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EMC86624.1 - 9.3e-07 28.9 0.3 0.0013 18.8 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC86624.1 - 3e-06 26.1 0.5 0.0016 17.6 0.0 2.5 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 EMC86624.1 - 7.1e-05 22.7 0.0 0.064 13.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_8 PF13833.1 EMC86624.1 - 0.00011 21.7 0.1 0.44 10.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 EMC86624.1 - 0.00014 21.7 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EF-hand_5 PF13202.1 EMC86624.1 - 0.0024 17.1 0.1 0.0049 16.1 0.0 1.6 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.4 EMC86624.1 - 0.015 15.3 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EMC86624.1 - 0.042 13.5 1.2 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 EF hand ABC_tran PF00005.22 EMC86624.1 - 0.052 13.8 0.0 5.4 7.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EMC86624.1 - 0.057 13.3 0.0 6.5 6.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain Rhomboid PF01694.17 EMC86625.1 - 4.2e-34 117.6 8.4 9.4e-34 116.5 5.8 1.6 1 0 0 1 1 1 1 Rhomboid family U-box PF04564.10 EMC86626.1 - 2.9e-31 107.2 0.0 4.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.23 EMC86626.1 - 2.3e-16 58.5 7.0 5.3e-10 38.4 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC86626.1 - 4.2e-14 51.9 3.8 9.5e-14 50.8 2.6 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EMC86626.1 - 1.7e-12 46.2 6.1 8.1e-06 25.3 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86626.1 - 5.3e-12 45.4 2.6 1.3e-11 44.2 1.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC86626.1 - 7.6e-11 42.0 2.1 1.9e-10 40.7 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMC86626.1 - 1.1e-09 37.3 3.8 0.00027 20.4 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86626.1 - 1.3e-07 32.1 0.7 2.7e-07 31.0 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86626.1 - 1.9e-07 31.3 2.5 4.6e-07 30.0 1.7 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86626.1 - 6.6e-07 29.0 0.6 0.014 15.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC86626.1 - 1.8e-05 24.5 1.2 5e-05 23.0 0.8 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC86626.1 - 5e-05 23.5 0.7 0.0076 16.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC86626.1 - 0.00014 21.3 3.1 0.084 12.7 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC86626.1 - 0.00061 20.0 2.6 1 9.9 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMC86626.1 - 0.01 15.0 2.0 0.06 12.6 0.1 2.3 2 0 0 2 2 2 1 SHNi-TPR Rsc14 PF08586.5 EMC86626.1 - 0.035 14.5 1.9 4.9 7.6 0.0 3.1 1 1 1 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit TPR_10 PF13374.1 EMC86626.1 - 0.18 11.7 1.7 5.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMC86626.1 - 1.8 8.7 8.5 8 6.6 1.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Cupin_8 PF13621.1 EMC86627.1 - 0.0009 18.8 0.0 0.0071 15.8 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain WD40 PF00400.27 EMC86628.1 - 1.6e-27 94.3 3.5 4.4e-11 42.2 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat LRR_4 PF12799.2 EMC86629.1 - 2.8e-07 29.9 2.1 0.0015 18.1 0.0 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC86629.1 - 5.1e-05 22.9 0.8 0.33 11.1 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 EMC86629.1 - 0.00047 19.8 2.3 2.6 8.3 0.0 3.4 2 1 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EMC86629.1 - 0.00071 19.3 6.3 1.1 9.8 0.3 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_8 PF13855.1 EMC86629.1 - 0.0013 18.4 1.9 0.0024 17.5 1.3 1.5 1 1 0 1 1 1 1 Leucine rich repeat F-box PF00646.28 EMC86630.1 - 0.0055 16.3 1.5 0.011 15.3 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC86630.1 - 0.006 16.2 1.3 0.006 16.2 0.9 1.7 2 0 0 2 2 2 1 F-box-like Methyltransf_26 PF13659.1 EMC86632.1 - 0.0046 16.9 0.0 0.0059 16.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain IL22 PF14565.1 EMC86633.1 - 0.016 15.3 2.1 0.12 12.4 0.1 2.4 1 1 1 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF1664 PF07889.7 EMC86633.1 - 0.043 13.5 13.2 0.28 10.9 4.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) PyocinActivator PF11112.3 EMC86633.1 - 0.071 12.9 0.7 0.4 10.5 0.0 2.5 3 0 0 3 3 3 0 Pyocin activator protein PrtN IncA PF04156.9 EMC86633.1 - 0.12 11.9 28.0 0.14 11.7 8.7 2.8 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 EMC86633.1 - 0.13 12.0 29.7 0.72 9.7 8.5 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EMC86633.1 - 0.27 10.6 27.1 0.31 10.4 6.9 3.1 1 1 1 3 3 3 0 Intermediate filament protein Hemerythrin PF01814.18 EMC86633.1 - 0.3 11.2 9.9 0.12 12.5 1.1 3.6 2 2 2 4 4 4 0 Hemerythrin HHE cation binding domain CAGE1 PF15066.1 EMC86633.1 - 2 6.7 14.5 0.4 9.0 4.9 2.6 2 1 0 2 2 2 0 Cancer-associated gene protein 1 family TPR_MLP1_2 PF07926.7 EMC86633.1 - 2 8.1 26.7 4.3 7.0 5.3 3.0 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein FH2 PF02181.18 EMC86633.1 - 4.8 5.9 13.7 1.2 7.9 3.5 2.5 2 1 0 2 2 2 0 Formin Homology 2 Domain DUF883 PF05957.8 EMC86633.1 - 6.8 7.1 20.1 19 5.7 1.4 4.8 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF883) FliD_N PF02465.13 EMC86633.1 - 8.4 6.8 13.8 13 6.2 2.6 3.7 3 2 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus LRR_8 PF13855.1 EMC86634.1 - 1.7e-87 287.0 67.7 9e-18 63.7 1.0 9.2 4 2 5 10 10 10 8 Leucine rich repeat LRR_4 PF12799.2 EMC86634.1 - 5.2e-45 150.4 63.8 3.4e-07 29.7 0.0 11.8 5 2 10 15 15 15 14 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC86634.1 - 1.1e-35 122.1 0.0 4.9e-10 39.2 0.0 4.4 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC86634.1 - 2.1e-28 93.9 76.6 0.21 11.7 0.2 20.7 22 0 0 22 22 22 14 Leucine Rich Repeat LRR_7 PF13504.1 EMC86634.1 - 1.1e-09 36.8 83.4 1.1 9.6 0.2 19.1 21 1 0 21 21 21 7 Leucine rich repeat LRR_9 PF14580.1 EMC86634.1 - 7.3e-09 35.4 10.5 0.0047 16.4 0.4 4.9 1 1 4 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.1 EMC86634.1 - 6.3e-08 31.9 58.9 2 8.7 0.0 15.6 16 2 2 18 18 18 5 Leucine Rich repeat LRRNT PF01462.13 EMC86634.1 - 7.7e-07 28.4 1.9 7.7e-07 28.4 1.3 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Herpes_BTRF1 PF04682.7 EMC86634.1 - 0.97 8.7 10.3 0.082 12.2 0.7 3.3 2 1 2 4 4 4 0 Herpesvirus BTRF1 protein conserved region ParA PF10609.4 EMC86635.1 - 1.1e-34 118.0 0.0 2.2e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMC86635.1 - 4e-16 58.9 0.0 6.3e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EMC86635.1 - 2e-08 33.6 0.0 6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EMC86635.1 - 2e-07 30.8 0.0 7.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EMC86635.1 - 2.2e-07 30.9 0.0 1.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EMC86635.1 - 5.5e-07 28.9 0.4 3.7e-06 26.1 0.0 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase ArgK PF03308.11 EMC86635.1 - 5.2e-05 22.1 0.1 7.7e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 ArgK protein Fer4_NifH PF00142.13 EMC86635.1 - 0.00021 20.5 0.0 0.0092 15.1 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 EMC86635.1 - 0.0066 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein APS_kinase PF01583.15 EMC86635.1 - 0.0066 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 EMC86635.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.17 EMC86635.1 - 0.019 14.4 0.0 0.083 12.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EMC86635.1 - 0.025 13.9 0.1 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMC86635.1 - 0.03 15.1 0.3 0.13 13.0 0.4 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMC86635.1 - 0.073 13.3 0.6 0.096 12.9 0.4 1.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EMC86635.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EMC86635.1 - 0.092 11.9 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EMC86635.1 - 0.15 11.7 0.2 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 NTPase SPRY PF00622.23 EMC86636.1 - 5.7e-17 61.9 0.2 2e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 SPRY domain SOCS_box PF07525.11 EMC86636.1 - 0.0029 17.4 2.7 0.0068 16.2 1.8 1.6 1 0 0 1 1 1 1 SOCS box NDK PF00334.14 EMC86637.1 - 1.8e-55 186.4 0.0 2e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EMC86637.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ UBN_AB PF14075.1 EMC86638.1 - 7.5e-59 198.9 0.9 8e-41 140.0 0.1 3.7 2 2 1 3 3 3 2 Ubinuclein conserved middle domain HUN PF08729.5 EMC86638.1 - 3.7e-20 71.5 0.4 3.7e-20 71.5 0.3 3.5 3 0 0 3 3 3 1 HPC2 and ubinuclein domain Cellulose_synt PF03552.9 EMC86638.1 - 1 7.5 2.7 1.6 6.9 1.9 1.2 1 0 0 1 1 1 0 Cellulose synthase Plectin PF00681.15 EMC86639.1 - 0.00032 20.1 0.0 0.02 14.4 0.0 2.9 2 0 0 2 2 2 1 Plectin repeat ATG16 PF08614.6 EMC86639.1 - 0.00095 19.0 15.9 0.00095 19.0 11.1 13.2 6 2 7 13 13 13 1 Autophagy protein 16 (ATG16) PDZ PF00595.19 EMC86640.1 - 1.5e-11 44.3 0.0 3.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF812 PF05667.6 EMC86640.1 - 0.0055 15.2 9.6 0.0071 14.9 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF1192 PF06698.6 EMC86640.1 - 0.039 13.7 4.4 1 9.2 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Laminin_II PF06009.7 EMC86640.1 - 0.046 13.4 8.7 0.089 12.5 6.0 1.5 1 0 0 1 1 1 0 Laminin Domain II PDZ_2 PF13180.1 EMC86640.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain CCDC74_C PF14917.1 EMC86640.1 - 0.24 11.4 5.0 0.73 9.9 3.5 1.9 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal TPR_MLP1_2 PF07926.7 EMC86640.1 - 0.33 10.7 21.0 0.12 12.1 6.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Membralin PF09746.4 EMC86640.1 - 0.52 9.3 3.2 0.78 8.7 2.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein AAA_23 PF13476.1 EMC86640.1 - 0.8 10.0 6.0 1.2 9.4 3.6 1.5 1 1 0 1 1 1 0 AAA domain Med9 PF07544.8 EMC86640.1 - 0.98 9.1 8.2 0.63 9.8 0.6 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 EMC86640.1 - 3 7.4 16.5 0.4 10.2 2.9 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.1 EMC86640.1 - 5.9 6.8 20.0 8.8 6.2 12.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 EMC86640.1 - 6.6 6.2 16.9 1 8.9 6.6 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EMC86640.1 - 8.3 6.5 10.5 6.7 6.8 5.9 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EMC86640.1 - 10 5.0 17.6 15 4.4 11.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 PRELI PF04707.9 EMC86641.1 - 1.8e-47 160.8 0.5 2.8e-47 160.2 0.3 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.15 EMC86641.1 - 6.3e-43 146.0 0.0 1.8e-42 144.5 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC86641.1 - 5e-10 39.3 0.2 1.3e-09 38.0 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMC86641.1 - 0.017 14.9 0.0 0.069 13.0 0.0 2.0 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2233 PF09992.4 EMC86642.1 - 1e-37 129.8 0.1 1.3e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2233) EGF_2 PF07974.8 EMC86642.1 - 0.00047 20.2 12.6 0.00047 20.2 8.7 4.9 3 1 1 4 4 4 3 EGF-like domain hEGF PF12661.2 EMC86642.1 - 0.025 14.6 21.4 0.057 13.5 1.5 4.3 3 0 0 3 3 3 0 Human growth factor-like EGF Glyco_trans_1_4 PF13692.1 EMC86643.1 - 4.9e-20 72.0 0.0 9.2e-20 71.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EMC86643.1 - 2e-10 40.3 0.0 2.9e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMC86643.1 - 0.0017 18.5 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EMC86643.1 - 0.011 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_16 PF10294.4 EMC86644.1 - 5.2e-18 65.0 0.1 9e-09 35.0 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EMC86644.1 - 0.0074 16.8 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC86644.1 - 0.11 13.0 0.1 0.26 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMC86644.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TSKS PF15358.1 EMC86645.1 - 0.049 11.7 0.9 0.052 11.7 0.7 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Peptidase_C2 PF00648.16 EMC86646.1 - 1e-84 284.0 0.0 1.5e-84 283.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.13 EMC86646.1 - 1.7e-26 90.9 69.7 5.6e-08 31.7 1.3 7.6 8 0 0 8 8 8 6 Zn-finger in Ran binding protein and others DZR PF12773.2 EMC86646.1 - 5.3e-08 32.5 53.4 0.0054 16.5 5.9 6.5 5 1 1 6 6 6 5 Double zinc ribbon zf-C2H2_7 PF15269.1 EMC86647.1 - 4.8e-39 132.0 11.7 1e-38 130.9 8.1 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C2H2 PF00096.21 EMC86647.1 - 4.8 7.7 7.8 13 6.3 5.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type NHL PF01436.16 EMC86648.1 - 2.1e-12 46.3 2.5 3.4e-05 23.5 0.1 3.1 3 0 0 3 3 3 2 NHL repeat SGL PF08450.7 EMC86648.1 - 0.024 14.0 0.0 0.22 10.8 0.0 2.0 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Gpi1 PF05024.10 EMC86649.1 - 3.8e-75 251.7 9.5 7.6e-75 250.7 6.6 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.17 EMC86650.1 - 2.1e-34 118.2 0.0 2.4e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC86650.1 - 9.6e-10 38.9 0.0 1.4e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC86650.1 - 0.0029 16.8 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF938 PF06080.7 EMC86651.1 - 1.1e-42 145.9 0.0 1.2e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 EMC86651.1 - 5.1e-06 26.8 0.0 7.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC86651.1 - 7.5e-06 25.4 0.0 2e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMC86651.1 - 1.2e-05 25.8 0.0 1.9e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC86651.1 - 0.00044 20.6 0.0 0.00082 19.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC86651.1 - 0.0014 18.9 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC86651.1 - 0.0018 18.2 0.1 0.0063 16.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC86651.1 - 0.008 15.9 0.0 0.012 15.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC86651.1 - 0.073 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAM195 PF14799.1 EMC86652.1 - 1.6e-31 108.0 0.2 1.8e-31 107.9 0.1 1.0 1 0 0 1 1 1 1 FAM195 family LAP2alpha PF11560.3 EMC86652.1 - 0.051 12.7 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha PPDFL PF15060.1 EMC86652.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Differentiation and proliferation regulator ABC2_membrane_3 PF12698.2 EMC86653.1 - 1.7e-61 208.1 37.7 3e-33 115.3 16.0 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 EMC86653.1 - 5e-49 166.1 0.0 5.6e-24 84.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMC86653.1 - 2e-17 64.0 0.1 5.8e-05 23.1 0.0 4.3 3 1 0 4 4 4 3 AAA domain SbcCD_C PF13558.1 EMC86653.1 - 7.8e-05 22.5 0.0 0.006 16.4 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EMC86653.1 - 0.00011 22.5 3.1 0.0057 17.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EMC86653.1 - 0.00099 18.3 1.0 0.013 14.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EMC86653.1 - 0.0012 18.0 0.0 0.4 9.6 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 EMC86653.1 - 0.0026 17.2 3.2 0.061 12.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 EMC86653.1 - 0.026 14.1 0.8 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EMC86653.1 - 0.027 13.6 0.2 9.8 5.3 0.0 3.2 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain Arf PF00025.16 EMC86653.1 - 0.068 12.4 0.7 11 5.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.1 EMC86653.1 - 0.076 13.1 0.5 5.7 7.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EMC86653.1 - 0.12 11.7 5.4 0.85 9.0 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EMC86653.1 - 0.14 12.0 0.1 12 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMC86653.1 - 0.17 11.5 1.9 2.6 7.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 EMC86653.1 - 0.2 10.0 0.2 2.2 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EMC86653.1 - 0.47 9.8 2.1 12 5.2 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RELT PF12606.3 EMC86653.1 - 3.4 6.8 5.1 10 5.3 3.6 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Pkinase PF00069.20 EMC86654.1 - 2.7e-12 46.4 0.0 3.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86654.1 - 9.6e-06 24.8 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclin_N PF00134.18 EMC86655.1 - 5.5e-26 90.6 0.3 1.1e-25 89.6 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC86655.1 - 1.2e-10 41.2 0.1 4.2e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain fn3 PF00041.16 EMC86658.1 - 7.8e-12 45.1 0.2 1.5e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ank_2 PF12796.2 EMC86658.1 - 6e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC86658.1 - 0.00011 22.5 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC86658.1 - 0.0051 17.0 0.0 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EMC86658.1 - 0.007 16.1 0.1 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Big_5 PF13205.1 EMC86658.1 - 0.063 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain Tmemb_cc2 PF10267.4 EMC86659.1 - 0.0029 16.2 1.4 0.0029 16.2 0.9 1.5 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Retrotrans_gag PF03732.12 EMC86659.1 - 0.022 14.8 1.8 0.04 13.9 1.0 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein DUF1221 PF06760.6 EMC86659.1 - 0.06 12.5 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) TLD PF07534.11 EMC86661.1 - 4.3e-29 101.2 0.1 4.4e-27 94.7 0.1 2.3 1 1 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 EMC86661.1 - 2.1e-23 82.9 0.1 3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ATP-synt_C PF00137.16 EMC86662.1 - 4.9e-31 106.4 29.2 5.1e-19 67.9 8.2 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Amidohydro_1 PF01979.15 EMC86663.1 - 2.9e-13 50.1 1.4 7.2e-13 48.8 0.9 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC86663.1 - 3.9e-09 36.9 0.4 1e-07 32.2 0.3 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMC86663.1 - 0.00014 21.6 0.0 0.00036 20.2 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMC86663.1 - 0.00074 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family DUF4615 PF15393.1 EMC86664.1 - 7e-41 139.3 2.6 7e-41 139.3 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4615) Rep_4 PF05797.6 EMC86664.1 - 0.071 11.8 5.8 0.096 11.3 4.0 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF2408 PF10303.4 EMC86665.1 - 0.015 15.4 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PX PF00787.19 EMC86665.1 - 0.033 13.9 0.1 0.054 13.2 0.1 1.4 1 0 0 1 1 1 0 PX domain EssA PF10661.4 EMC86665.1 - 0.038 13.6 0.5 0.043 13.4 0.4 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Sec2p PF06428.6 EMC86665.1 - 0.26 11.1 2.1 0.2 11.5 0.2 1.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p RP-C_C PF11800.3 EMC86665.1 - 0.29 10.8 2.9 0.42 10.2 2.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SelP_N PF04592.9 EMC86665.1 - 3.7 6.8 10.3 4 6.7 7.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EMC86665.1 - 7.8 5.4 10.5 8.6 5.2 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LTD PF00932.14 EMC86666.1 - 8.8e-05 22.5 0.1 0.00026 21.0 0.1 1.8 1 1 0 1 1 1 1 Lamin Tail Domain NPV_P10 PF05531.7 EMC86667.1 - 0.013 15.7 2.0 0.015 15.5 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 EMC86667.1 - 1.2 9.1 8.8 2.2 8.2 6.1 1.3 1 0 0 1 1 1 0 FlxA-like protein RRM_1 PF00076.17 EMC86668.1 - 3.5e-20 71.4 0.0 5.1e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC86668.1 - 1.2e-15 57.1 0.0 1.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC86668.1 - 3.3e-10 39.6 0.0 4.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC86668.1 - 0.00055 19.6 0.0 0.0018 17.9 0.0 1.9 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 EMC86668.1 - 0.001 18.8 0.0 0.0027 17.5 0.0 1.7 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMC86668.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Macoilin PF09726.4 EMC86668.1 - 0.5 8.5 26.2 0.72 8.0 18.1 1.2 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 EMC86668.1 - 0.55 10.5 26.7 0.87 9.9 18.2 1.5 1 1 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.10 EMC86668.1 - 6.4 5.2 6.2 8.2 4.9 4.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Telomere_reg-2 PF10193.4 EMC86669.1 - 1.4e-36 125.1 0.2 4.2e-36 123.6 0.1 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Melibiase PF02065.13 EMC86669.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Melibiase L_HGMIC_fpl PF10242.4 EMC86670.1 - 4.6e-05 23.4 1.4 4.6e-05 23.4 1.0 2.3 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 EMC86670.1 - 0.00044 19.5 0.1 0.00044 19.5 0.1 2.1 2 1 1 3 3 3 1 Clc-like Claudin_3 PF06653.6 EMC86670.1 - 0.00058 19.6 4.3 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 Tight junction protein, Claudin-like Claudin_2 PF13903.1 EMC86670.1 - 0.046 13.4 7.8 0.56 9.8 5.4 2.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Neurensin PF14927.1 EMC86670.1 - 0.054 12.8 0.3 0.14 11.5 0.1 1.9 1 1 0 1 1 1 0 Neurensin Myb_DNA-binding PF00249.26 EMC86671.1 - 0.019 14.9 0.0 0.11 12.6 0.0 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain Jnk-SapK_ap_N PF09744.4 EMC86673.1 - 3.7e-46 156.9 17.2 3.7e-46 156.9 11.9 3.0 2 2 0 2 2 2 1 JNK_SAPK-associated protein-1 Baculo_LEF-10 PF07206.6 EMC86673.1 - 0.32 10.6 3.2 0.24 11.0 0.1 2.3 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) NAD_binding_2 PF03446.10 EMC86675.1 - 7.4e-41 139.6 0.0 1.5e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMC86675.1 - 5.4e-23 81.3 1.3 9.6e-23 80.5 0.9 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.12 EMC86675.1 - 3.7e-17 62.3 0.9 8.7e-17 61.1 0.6 1.7 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.12 EMC86675.1 - 6.2e-08 32.9 0.0 1.7e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMC86675.1 - 2.5e-05 23.5 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMC86675.1 - 0.00023 21.2 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EMC86675.1 - 0.0005 19.5 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMC86675.1 - 0.0045 16.6 1.3 0.006 16.2 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMC86675.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus BSP_II PF05432.6 EMC86675.1 - 0.13 11.5 6.1 0.11 11.7 1.5 2.4 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) AT_hook PF02178.14 EMC86675.1 - 3.8 7.4 11.9 0.09 12.5 2.8 2.6 2 0 0 2 2 2 0 AT hook motif Rogdi_lz PF10259.4 EMC86676.1 - 7.8e-63 212.1 0.4 1.4e-62 211.3 0.3 1.4 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein Takusan PF04822.8 EMC86676.1 - 0.14 11.9 1.0 0.32 10.7 0.7 1.6 1 0 0 1 1 1 0 Takusan 7tm_1 PF00001.16 EMC86677.1 - 1.3e-59 201.4 16.3 1.7e-59 201.0 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC86677.1 - 5.1e-13 48.8 12.1 1.6e-11 43.9 8.4 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 EMC86677.1 - 8.5e-08 31.6 13.3 8.5e-08 31.6 9.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Flavi_capsid PF01003.14 EMC86677.1 - 0.13 11.8 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus capsid protein C DUF420 PF04238.7 EMC86677.1 - 1.4 8.8 14.3 0.046 13.6 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF420) 7tm_1 PF00001.16 EMC86678.1 - 2e-25 89.4 27.8 2.6e-25 89.0 19.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC86678.1 - 2.2e-09 36.9 28.6 4.9e-06 25.8 8.3 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Thioredoxin_6 PF13848.1 EMC86679.1 - 1.7e-08 34.5 0.5 2.7e-08 33.8 0.3 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain AMP-binding PF00501.23 EMC86680.1 - 1.6e-88 296.9 0.0 2.1e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC86680.1 - 2.2e-21 76.5 1.3 5.3e-21 75.3 0.9 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EMC86681.1 - 2.3e-83 279.9 0.0 3.1e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC86681.1 - 4.6e-21 75.5 0.4 8.9e-21 74.6 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain THUMP PF02926.12 EMC86682.1 - 4e-24 85.1 0.8 7.1e-24 84.3 0.5 1.6 1 1 0 1 1 1 1 THUMP domain DUF1796 PF08795.5 EMC86682.1 - 0.01 15.4 0.2 0.021 14.4 0.2 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) RNase_P_Rpp14 PF01900.14 EMC86682.1 - 0.033 14.1 0.0 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 Rpp14/Pop5 family BHD_1 PF10403.4 EMC86682.1 - 0.052 13.0 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 AMP-binding PF00501.23 EMC86683.1 - 8.9e-89 297.7 0.0 1.1e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC86683.1 - 6.9e-21 74.9 2.5 1e-20 74.4 1.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RNase_T PF00929.19 EMC86684.1 - 3.2e-20 73.0 0.0 4.8e-20 72.4 0.0 1.3 1 1 0 1 1 1 1 Exonuclease Tnp_DNA_bind PF14706.1 EMC86684.1 - 0.13 12.0 0.4 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Transposase DNA-binding RRM_1 PF00076.17 EMC86685.1 - 9.6e-22 76.4 0.0 3.5e-13 48.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EMC86685.1 - 4.9e-21 75.7 0.0 1.4e-20 74.2 0.0 1.8 2 0 0 2 2 2 1 Exonuclease RRM_6 PF14259.1 EMC86685.1 - 8.9e-13 48.0 0.0 3.5e-08 33.3 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC86685.1 - 2.6e-07 30.3 0.0 0.0071 16.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4513 PF14983.1 EMC86685.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) Cullin_binding PF03556.10 EMC86686.1 - 8.8e-36 122.5 0.1 1.5e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 Cullin binding Complex1_LYR PF05347.10 EMC86687.1 - 6.3e-18 64.3 0.1 1.1e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC86687.1 - 1.5e-13 50.7 0.1 2.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMC86687.1 - 0.11 12.9 0.4 0.17 12.4 0.1 1.4 2 0 0 2 2 2 0 Complex1_LYR-like DUF1119 PF06550.6 EMC86688.1 - 1.3 8.1 14.6 2.1 7.4 10.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1119) DUF1129 PF06570.6 EMC86688.1 - 4.3 6.5 5.2 6.6 5.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Zona_pellucida PF00100.18 EMC86689.1 - 1e-49 169.3 0.2 4.6e-49 167.2 0.0 2.0 2 0 0 2 2 2 1 Zona pellucida-like domain Ank_2 PF12796.2 EMC86690.1 - 1.1e-21 76.9 0.6 1.5e-17 63.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86690.1 - 2.5e-18 64.9 1.7 2.3e-10 39.7 0.3 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMC86690.1 - 6.5e-18 64.3 1.1 1.6e-10 40.8 0.2 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC86690.1 - 2.3e-16 59.8 1.2 4.3e-08 33.4 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86690.1 - 7.6e-14 50.4 0.4 1.1e-06 28.2 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat SAM_1 PF00536.25 EMC86690.1 - 1.4e-07 31.5 0.0 3.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_S18 PF01084.15 EMC86690.1 - 0.00063 19.5 0.7 0.0014 18.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 OCD_Mu_crystall PF02423.10 EMC86691.1 - 1.2e-88 296.9 0.2 1.3e-88 296.8 0.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EMC86691.1 - 8.7e-09 35.5 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EMC86691.1 - 8.2e-05 22.4 0.3 0.00052 19.8 0.1 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMC86691.1 - 0.00016 22.0 0.0 0.00041 20.7 0.0 1.8 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Peptidase_M16 PF00675.15 EMC86692.1 - 4.6e-31 107.5 0.0 7.6e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMC86692.1 - 1.5e-25 89.9 0.1 1.5e-24 86.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Bac_Ubq_Cox PF01654.12 EMC86693.1 - 1.2e-05 23.9 3.1 1.3e-05 23.7 2.2 1.1 1 0 0 1 1 1 1 Bacterial Cytochrome Ubiquinol Oxidase Claudin_2 PF13903.1 EMC86693.1 - 8.7e-05 22.2 3.9 0.00017 21.3 2.7 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TauE PF01925.14 EMC86693.1 - 0.038 13.4 5.3 0.046 13.1 3.7 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF998 PF06197.8 EMC86693.1 - 0.087 12.1 9.1 0.21 10.8 6.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) L_HGMIC_fpl PF10242.4 EMC86693.1 - 0.099 12.6 6.1 0.15 12.0 4.0 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Tetraspannin PF00335.15 EMC86693.1 - 0.17 11.1 7.6 0.22 10.7 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family SLAC1 PF03595.12 EMC86693.1 - 0.19 10.3 10.6 1.1 7.8 7.3 1.9 1 1 0 1 1 1 0 Voltage-dependent anion channel HlyIII PF03006.15 EMC86693.1 - 0.21 11.0 5.8 0.054 12.9 1.5 1.6 1 1 0 1 1 1 0 Haemolysin-III related DUF456 PF04306.8 EMC86693.1 - 0.23 11.4 8.9 0.12 12.4 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF2269 PF10027.4 EMC86693.1 - 0.55 9.9 4.8 0.99 9.1 3.3 1.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF204 PF02659.10 EMC86693.1 - 1.1 9.4 5.3 0.27 11.4 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF 7TMR-DISM_7TM PF07695.6 EMC86693.1 - 1.7 8.2 13.0 4.4 6.9 8.2 1.8 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4131 PF13567.1 EMC86693.1 - 1.9 7.8 6.9 0.33 10.3 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1218 PF06749.7 EMC86693.1 - 2.4 8.6 6.4 1.3 9.5 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF423 PF04241.10 EMC86693.1 - 2.9 7.8 6.3 0.36 10.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF2975 PF11188.3 EMC86693.1 - 7 6.3 7.9 20 4.9 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2721 PF11026.3 EMC86693.1 - 7.5 6.2 10.3 3.8 7.1 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) VWA_3 PF13768.1 EMC86694.1 - 0.00012 21.8 0.0 0.00049 19.8 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain 3Beta_HSD PF01073.14 EMC86695.1 - 3.7e-67 225.9 0.0 4.7e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC86695.1 - 1.4e-32 113.0 0.0 1.8e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC86695.1 - 1.5e-12 47.0 0.0 9.2e-11 41.1 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EMC86695.1 - 7.6e-12 45.6 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC86695.1 - 1.3e-10 40.6 0.0 1.6e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMC86695.1 - 4.6e-08 32.3 0.5 2.2e-07 30.0 0.2 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMC86695.1 - 3.8e-05 23.0 0.0 5.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMC86695.1 - 0.005 16.7 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EMC86696.1 - 3.2e-67 226.1 0.0 4.1e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC86696.1 - 1.9e-27 96.2 0.0 2.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC86696.1 - 7.3e-12 44.7 0.0 1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMC86696.1 - 2e-08 33.4 0.0 3.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMC86696.1 - 2.3e-07 30.0 0.4 1.2e-06 27.6 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMC86696.1 - 2.5e-07 30.8 0.0 4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMC86696.1 - 0.00015 21.1 0.0 0.00042 19.6 0.0 1.8 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EMC86696.1 - 0.14 12.0 0.3 0.36 10.7 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Alpha_kinase PF02816.13 EMC86697.1 - 2.5e-55 187.0 0.2 3.8e-55 186.4 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.7 EMC86697.1 - 1.2e-06 28.9 12.3 0.2 12.3 0.1 5.2 5 0 0 5 5 5 3 Sel1 repeat Sin_N PF04801.8 EMC86698.1 - 2.1e-162 540.8 2.7 2.1e-162 540.8 1.9 1.9 3 0 0 3 3 3 1 Sin-like protein conserved region TORC_M PF12885.2 EMC86698.1 - 0.33 10.6 3.9 0.26 11.0 1.2 1.9 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain PRKCSH_1 PF13015.1 EMC86699.1 - 3.4e-10 39.6 0.4 2.4e-09 36.8 0.0 2.2 1 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EMC86699.1 - 7.1e-07 29.9 3.0 7.1e-07 29.9 2.1 1.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein DPM3 PF08285.6 EMC86699.1 - 0.078 12.8 0.3 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4116 PF13475.1 EMC86699.1 - 0.079 12.4 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF530 PF04409.7 EMC86699.1 - 0.098 10.7 5.7 0.13 10.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) DUF4582 PF15189.1 EMC86699.1 - 0.12 11.5 0.7 0.2 10.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Transposase_22 PF02994.9 EMC86699.1 - 1 7.7 6.3 1.4 7.3 4.4 1.1 1 0 0 1 1 1 0 L1 transposable element DUF367 PF04034.8 EMC86700.1 - 2.2e-50 169.5 0.0 2.8e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EMC86700.1 - 1.2e-12 47.1 1.3 2.3e-12 46.2 0.9 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Cwf_Cwc_15 PF04889.7 EMC86700.1 - 0.26 10.9 3.1 0.35 10.5 2.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UQ_con PF00179.21 EMC86701.1 - 9.8e-49 164.3 0.0 1.1e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC86701.1 - 0.00018 21.2 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Pkinase PF00069.20 EMC86702.1 - 3.7e-66 222.9 0.0 4.9e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.1 EMC86702.1 - 1.4e-43 146.9 0.0 2.7e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.12 EMC86702.1 - 4.1e-34 117.8 0.0 5.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC86702.1 - 2.2e-07 30.1 0.0 3.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC86702.1 - 0.00016 21.5 0.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMC86702.1 - 0.0032 16.5 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 EMC86702.1 - 0.04 12.4 0.0 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC fn3 PF00041.16 EMC86703.1 - 0.0077 16.3 0.1 0.012 15.7 0.1 1.4 1 1 0 1 1 1 1 Fibronectin type III domain EpoR_lig-bind PF09067.5 EMC86704.1 - 5.9e-05 23.0 0.7 0.00017 21.5 0.5 1.7 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 EMC86704.1 - 0.00011 22.2 0.4 0.00044 20.3 0.3 2.1 1 1 0 1 1 1 1 Fibronectin type III domain Interfer-bind PF09294.5 EMC86704.1 - 0.031 14.2 0.1 0.089 12.8 0.1 1.8 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III LRR19-TM PF15176.1 EMC86704.1 - 0.081 12.6 1.8 0.15 11.7 0.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain IL4Ra_N PF09238.5 EMC86705.1 - 2.3e-30 104.5 0.4 7.7e-30 102.8 0.3 1.9 1 0 0 1 1 1 1 Interleukin-4 receptor alpha chain, N-terminal fn3 PF00041.16 EMC86705.1 - 2.2e-05 24.5 0.3 0.00061 19.8 0.5 2.3 2 0 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.5 EMC86705.1 - 3.4e-05 23.9 0.8 6.4e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 EMC86705.1 - 0.0077 16.2 0.9 0.0077 16.2 0.6 1.9 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding SMC_Nse1 PF07574.8 EMC86706.1 - 5.7e-42 143.6 1.7 2.2e-41 141.6 1.2 1.7 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EMC86706.1 - 3e-09 36.7 14.0 3e-09 36.7 9.7 2.5 3 0 0 3 3 3 1 RING-like domain DUF1390 PF07150.6 EMC86706.1 - 0.01 15.2 0.3 0.016 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) RTX_C PF08339.5 EMC86706.1 - 0.028 14.1 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 RTX C-terminal domain DAP3 PF10236.4 EMC86706.1 - 0.031 13.2 0.5 0.047 12.6 0.3 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 zf-C3HC4_2 PF13923.1 EMC86706.1 - 0.033 14.2 14.6 0.12 12.4 10.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC86706.1 - 3.6 7.3 16.2 1.9 8.2 9.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cupin_8 PF13621.1 EMC86707.1 - 1.3e-48 165.6 0.1 1.6e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMC86707.1 - 2.3e-07 30.3 0.1 5.5e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EMC86707.1 - 0.019 15.1 0.0 0.074 13.2 0.0 1.9 1 1 0 1 1 1 0 JmjC domain, hydroxylase Sulfotransfer_1 PF00685.22 EMC86708.1 - 1.3e-42 145.9 0.0 1.5e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 EMC86708.1 - 0.0025 17.5 0.1 0.053 13.2 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_3 PF13469.1 EMC86708.1 - 0.081 13.8 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family UCH PF00443.24 EMC86709.1 - 4.6e-44 150.5 0.0 8.8e-44 149.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC86709.1 - 7.5e-11 42.0 0.0 1.9e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2296 PF10058.4 EMC86709.1 - 0.019 14.7 1.5 6.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-MIZ PF02891.15 EMC86709.1 - 1.4 8.5 11.7 0.33 10.4 3.6 2.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EMC86709.1 - 2.1 8.0 5.7 2.4 7.7 0.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ASC PF00858.19 EMC86710.1 - 1.4e-105 353.5 4.2 1.7e-105 353.2 2.9 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel tRNA-synt_1c PF00749.16 EMC86711.1 - 9.1e-84 280.7 0.0 1.5e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain LexA_DNA_bind PF01726.11 EMC86711.1 - 0.076 12.5 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 LexA DNA binding domain ubiquitin PF00240.18 EMC86712.1 - 2.2e-10 39.7 0.0 4.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EMC86712.1 - 0.003 17.7 0.0 0.024 14.8 0.0 2.4 1 1 1 2 2 2 1 Ubiquitin-like domain DUF4249 PF14054.1 EMC86712.1 - 0.023 14.0 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Epimerase_2 PF02350.14 EMC86712.1 - 0.067 11.9 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pkinase PF00069.20 EMC86713.1 - 3e-08 33.1 0.0 3.4e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86713.1 - 0.00021 20.4 0.0 0.00021 20.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EMC86714.1 - 9e-47 156.9 0.9 1.4e-22 79.4 0.0 2.4 2 0 0 2 2 2 2 POLO box duplicated region Pkinase PF00069.20 EMC86714.1 - 8.7e-46 156.1 0.0 1.3e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86714.1 - 5.4e-25 87.9 0.0 8e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC86714.1 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Hexapep PF00132.19 EMC86715.1 - 8.9e-17 59.7 19.8 1.4e-06 27.4 0.5 4.4 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMC86715.1 - 7.3e-06 25.4 13.4 0.00011 21.6 2.1 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EMC86715.1 - 0.079 11.5 0.1 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase EB PF01683.13 EMC86715.1 - 0.2 11.7 2.0 1.2 9.3 1.4 2.2 1 1 0 1 1 1 0 EB module PP-binding PF00550.20 EMC86717.1 - 9.4e-11 41.8 0.1 1e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EMC86717.1 - 0.00052 20.0 0.2 0.00057 19.8 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier Ago_hook PF10427.4 EMC86719.1 - 1.6e-25 89.8 14.6 1.6e-25 89.8 10.1 12.7 5 2 9 14 14 14 1 Argonaute hook RRM_5 PF13893.1 EMC86719.1 - 4e-06 26.5 0.0 7.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC86719.1 - 0.002 17.6 0.0 0.0052 16.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC86719.1 - 0.0028 17.5 0.0 0.0078 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SMP_2 PF10144.4 EMC86719.1 - 5.5 6.0 6.1 9.6 5.2 4.2 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin PMP22_Claudin PF00822.15 EMC86720.1 - 2.7e-33 114.9 0.6 3.8e-33 114.4 0.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC86720.1 - 4.7e-10 39.4 0.1 7.7e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 EMC86720.1 - 0.0031 16.8 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 Tetraspanin family AtpR PF12966.2 EMC86720.1 - 0.14 12.3 0.9 0.37 10.9 0.1 2.0 2 0 0 2 2 2 0 N-ATPase, AtpR subunit Pkinase_C PF00433.19 EMC86721.1 - 2.1e-11 44.1 2.4 2.3e-11 44.0 1.7 1.0 1 0 0 1 1 1 1 Protein kinase C terminal domain MIP PF00230.15 EMC86722.1 - 2.3e-49 167.8 11.8 3.2e-49 167.4 8.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein LCM PF04072.9 EMC86723.1 - 2e-19 69.8 0.0 3.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Filament PF00038.16 EMC86725.1 - 1.3e-57 195.6 13.9 1.7e-56 192.0 9.6 2.0 1 1 0 1 1 1 1 Intermediate filament protein DUF4407 PF14362.1 EMC86725.1 - 0.011 14.6 1.2 2.4 7.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2580 PF10824.3 EMC86725.1 - 0.016 15.5 0.0 7.2 7.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2580) IncA PF04156.9 EMC86725.1 - 0.021 14.4 0.6 0.021 14.4 0.4 2.4 3 0 0 3 3 3 0 IncA protein DUF4494 PF14902.1 EMC86725.1 - 0.11 12.1 0.2 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4494) Apolipoprotein PF01442.13 EMC86725.1 - 0.26 10.7 7.2 0.67 9.4 3.6 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Tektin PF03148.9 EMC86725.1 - 0.42 9.1 5.0 0.097 11.2 0.4 2.1 3 0 0 3 3 3 0 Tektin family DUF1192 PF06698.6 EMC86725.1 - 0.43 10.4 8.4 0.88 9.4 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) BRE1 PF08647.6 EMC86725.1 - 0.57 10.1 10.7 0.77 9.7 2.2 3.3 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF972 PF06156.8 EMC86725.1 - 0.6 10.4 7.3 1.1 9.6 2.3 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF4618 PF15397.1 EMC86725.1 - 0.7 9.1 11.4 2.2 7.5 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF1640 PF07798.6 EMC86725.1 - 0.85 9.6 5.0 2 8.4 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cep57_MT_bd PF06657.8 EMC86725.1 - 1.2 9.1 9.5 1.3 9.0 3.2 3.0 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Phage_Mu_Gam PF07352.7 EMC86725.1 - 1.4 8.4 4.5 2.7 7.4 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein OmpH PF03938.9 EMC86725.1 - 2.7 7.9 6.2 0.83 9.5 1.4 2.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Tropomyosin PF00261.15 EMC86725.1 - 2.7 7.0 11.4 2.7 7.0 1.3 2.8 2 1 0 2 2 2 0 Tropomyosin DUF904 PF06005.7 EMC86725.1 - 3.9 7.8 9.6 4.7 7.5 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) FliJ PF02050.11 EMC86725.1 - 7.8 6.5 13.6 0.52 10.3 4.2 2.6 3 0 0 3 3 3 0 Flagellar FliJ protein DUF4200 PF13863.1 EMC86725.1 - 9.4 6.1 13.2 3 7.7 1.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Tubulin_C PF03953.12 EMC86726.1 - 1.1e-51 174.0 0.0 1.9e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 EMC86726.1 - 1.9e-45 155.3 0.0 2.6e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain gp37_C PF12604.3 EMC86727.1 - 0.00093 18.9 12.5 0.19 11.5 0.0 4.7 2 1 1 4 4 4 3 Tail fiber protein gp37 C terminal V-set PF07686.12 EMC86731.1 - 6.8e-16 58.1 0.0 7.7e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC86731.1 - 2.5e-07 30.4 0.0 6.6e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC86731.1 - 1.9e-05 24.6 0.0 0.00063 19.8 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC86731.1 - 0.00011 22.1 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC86732.1 - 7e-16 58.1 0.0 8.5e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC86732.1 - 4.2e-07 29.7 0.0 7.8e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC86732.1 - 4.7e-06 26.6 0.0 0.00053 20.0 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC86732.1 - 0.00025 21.1 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Pico_P2B PF01552.12 EMC86732.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Picornavirus 2B protein PI3_PI4_kinase PF00454.22 EMC86735.1 - 2.4e-16 59.9 0.1 2.8e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF788 PF05620.6 EMC86735.1 - 0.0012 18.7 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) FATC PF02260.15 EMC86736.1 - 3.5e-13 48.7 0.1 4.8e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 FATC domain CDP-OH_P_transf PF01066.16 EMC86737.1 - 8.3e-11 42.0 24.1 1.9e-09 37.7 16.5 3.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase BEN PF10523.4 EMC86738.1 - 0.068 13.2 0.2 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 BEN domain zf-H2C2 PF09337.5 EMC86738.1 - 0.077 12.4 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger DUF2205 PF10224.4 EMC86739.1 - 0.076 12.5 0.3 0.076 12.5 0.2 2.7 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) HTH_37 PF13744.1 EMC86739.1 - 0.089 12.6 1.1 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CppA_C PF14507.1 EMC86739.1 - 0.24 11.5 3.5 0.34 11.0 0.2 2.6 1 1 1 3 3 3 0 CppA C-terminal DUF771 PF05595.6 EMC86739.1 - 0.35 10.7 4.4 53 3.8 0.9 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF771) DUF1664 PF07889.7 EMC86739.1 - 0.47 10.2 4.5 0.26 11.0 0.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) LAGLIDADG_1 PF00961.14 EMC86739.1 - 1.2 9.7 4.1 2 8.9 0.3 2.6 1 1 1 2 2 2 0 LAGLIDADG endonuclease DUF2968 PF11180.3 EMC86739.1 - 1.3 8.4 6.1 2.2 7.5 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1268 PF06896.6 EMC86739.1 - 1.7 9.0 7.6 0.85 9.9 2.0 2.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1268) Zot PF05707.7 EMC86740.1 - 0.011 15.1 0.2 0.014 14.9 0.1 1.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3552 PF12072.3 EMC86740.1 - 0.073 12.2 1.6 0.09 11.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Peptidase_M9_N PF08453.5 EMC86740.1 - 0.075 12.3 0.5 0.14 11.5 0.1 1.6 1 1 0 1 1 1 0 Peptidase family M9 N-terminal GAS PF13851.1 EMC86740.1 - 0.13 11.4 8.8 0.19 10.8 6.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DIL PF01843.14 EMC86740.1 - 0.13 12.1 1.4 0.16 11.8 1.0 1.3 1 0 0 1 1 1 0 DIL domain DUF972 PF06156.8 EMC86740.1 - 0.16 12.3 6.1 3.2 8.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FliJ PF02050.11 EMC86740.1 - 0.25 11.4 7.7 0.3 11.1 5.3 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Rep_fac_C PF08542.6 EMC86740.1 - 0.31 11.0 2.8 9.8 6.2 0.1 2.2 1 1 1 2 2 2 0 Replication factor C C-terminal domain Microtub_assoc PF07989.6 EMC86740.1 - 0.34 10.7 5.7 2.4 8.0 0.9 2.7 2 1 0 2 2 2 0 Microtubule associated DUF2205 PF10224.4 EMC86740.1 - 0.35 10.4 4.0 0.78 9.3 2.5 1.8 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF342 PF03961.8 EMC86740.1 - 0.62 8.4 4.9 0.67 8.2 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nnf1 PF03980.9 EMC86740.1 - 1.5 8.8 5.8 50 3.9 4.0 2.2 1 1 0 1 1 1 0 Nnf1 IncA PF04156.9 EMC86740.1 - 2.3 7.7 5.7 3.1 7.3 4.0 1.2 1 0 0 1 1 1 0 IncA protein Collagen PF01391.13 EMC86741.1 - 3.9e-42 141.6 161.4 1.1e-09 37.6 18.3 6.2 3 1 3 6 6 6 6 Collagen triple helix repeat (20 copies) VWA PF00092.23 EMC86741.1 - 4.4e-35 121.0 0.1 1.4e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Kunitz_BPTI PF00014.18 EMC86742.1 - 8.8e-19 67.4 8.7 9.6e-19 67.3 6.1 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain ThiF PF00899.16 EMC86744.1 - 7.7e-36 122.9 0.0 1.4e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.9 EMC86744.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MoeZ_MoeB PF05237.8 EMC86744.1 - 0.026 14.1 0.6 0.072 12.6 0.1 2.1 2 1 0 2 2 2 0 MoeZ/MoeB domain NAD_binding_7 PF13241.1 EMC86744.1 - 0.035 14.3 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMC86744.1 - 0.056 12.5 0.3 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EMC86744.1 - 0.17 10.9 0.3 0.26 10.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain APH PF01636.18 EMC86745.1 - 1.3e-45 156.0 0.1 2.2e-45 155.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.19 EMC86745.1 - 7.2e-35 120.2 1.1 1.2e-34 119.6 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC86745.1 - 2e-17 62.3 0.1 3.7e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMC86745.1 - 1.1e-13 51.7 0.3 2.8e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC86745.1 - 6.9e-13 48.9 0.5 1.8e-12 47.6 0.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EcKinase PF02958.15 EMC86745.1 - 0.00034 19.8 0.1 0.0012 18.1 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase RIO1 PF01163.17 EMC86745.1 - 0.017 14.5 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 RIO1 family HpaB_N PF11794.3 EMC86745.1 - 0.022 14.1 0.0 0.069 12.5 0.0 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Astro_capsid_p PF12226.3 EMC86745.1 - 0.21 10.7 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Turkey astrovirus capsid protein 7tm_1 PF00001.16 EMC86746.1 - 1.2e-51 175.3 17.3 1.5e-51 175.0 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86746.1 - 6e-07 28.8 16.0 8e-07 28.4 11.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF621 PF04789.10 EMC86746.1 - 0.0083 15.1 7.1 0.015 14.2 4.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF621) DUF202 PF02656.10 EMC86746.1 - 0.026 14.7 1.9 0.88 9.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF2339 PF10101.4 EMC86746.1 - 7.5 4.6 13.6 0.54 8.4 3.3 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2339) Adaptin_N PF01602.15 EMC86747.1 - 0.0014 17.0 1.7 0.37 9.0 0.1 2.6 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 EMC86747.1 - 0.0048 17.1 1.6 1.8 8.9 0.0 3.9 3 2 1 4 4 4 1 HEAT repeats DRIM PF07539.7 EMC86747.1 - 0.0068 15.8 0.3 0.16 11.4 0.0 3.0 3 0 0 3 3 3 1 Down-regulated in metastasis INTS5_N PF14837.1 EMC86747.1 - 0.0077 15.6 2.3 0.014 14.7 0.3 2.4 3 0 0 3 3 3 1 Integrator complex subunit 5 N-terminus HEAT PF02985.17 EMC86747.1 - 2.6 8.3 5.2 5.9 7.2 0.0 4.4 6 0 0 6 6 6 0 HEAT repeat DUF1367 PF07105.6 EMC86748.1 - 0.1 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) His_Phos_2 PF00328.17 EMC86749.1 - 6.6e-61 206.5 0.2 8.8e-61 206.1 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EMC86749.1 - 0.002 18.2 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EMC86750.1 - 6.9e-39 134.1 4.1 1.8e-38 132.8 2.8 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SecM PF06558.7 EMC86750.1 - 0.061 12.9 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) His_Phos_1 PF00300.17 EMC86750.1 - 0.1 12.6 0.1 0.29 11.2 0.0 1.8 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Copine PF07002.11 EMC86751.1 - 1.7e-64 216.0 0.1 3.5e-64 214.9 0.0 1.6 1 0 0 1 1 1 1 Copine C2 PF00168.25 EMC86751.1 - 2.6e-25 88.0 0.2 4e-13 49.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EMC86751.1 - 6.9e-09 35.8 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EMC86751.1 - 0.0014 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.20 EMC86752.1 - 6.2e-63 212.3 0.0 1.1e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86752.1 - 1.7e-44 151.8 0.0 2.7e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC86752.1 - 0.013 15.2 0.0 0.045 13.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RP-C_C PF11800.3 EMC86754.1 - 0.023 14.3 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Pkinase PF00069.20 EMC86755.1 - 1.4e-22 80.0 0.0 4.3e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.27 EMC86755.1 - 1e-18 66.4 11.8 7.7e-08 31.9 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.17 EMC86755.1 - 1.6e-11 43.2 1.1 0.043 13.9 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 EMC86755.1 - 6.2e-07 28.7 0.0 3.1e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EMC86755.1 - 0.00047 20.3 0.1 0.31 11.3 0.1 3.6 1 1 0 2 2 2 1 HEAT repeats Urm1 PF09138.6 EMC86758.1 - 7.9e-38 128.4 0.0 8.7e-38 128.3 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EMC86758.1 - 0.00083 19.7 0.0 0.00097 19.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family AMP-binding PF00501.23 EMC86760.1 - 5.5e-68 229.2 0.0 6.5e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC86760.1 - 0.00028 21.7 0.0 0.00052 20.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coq4 PF05019.8 EMC86761.1 - 3.4e-96 320.4 0.0 3.9e-96 320.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rnk_N PF14760.1 EMC86761.1 - 0.053 13.5 0.3 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Rnk N-terminus 7tm_1 PF00001.16 EMC86762.1 - 1.7e-17 63.4 4.0 1.9e-17 63.2 2.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86762.1 - 0.03 13.5 3.2 0.031 13.4 2.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_8 PF13855.1 EMC86764.1 - 1.5e-53 178.3 26.5 8.6e-16 57.4 0.5 5.4 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EMC86764.1 - 2.4e-31 106.8 17.8 4.3e-07 29.3 0.1 7.2 3 3 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC86764.1 - 5.9e-21 71.2 25.4 0.067 13.2 0.2 11.5 12 0 0 12 12 12 6 Leucine Rich Repeat LRR_5 PF13306.1 EMC86764.1 - 1.2e-19 70.2 0.0 9.3e-10 38.3 0.0 2.8 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC86764.1 - 3.6e-12 44.3 17.4 0.55 10.6 0.0 10.8 11 0 0 11 11 11 3 Leucine rich repeat LRR_9 PF14580.1 EMC86764.1 - 2.8e-09 36.7 0.4 0.0093 15.5 0.0 3.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 EMC86764.1 - 3.4e-07 29.6 23.2 1.8 8.9 0.0 9.9 10 1 1 11 11 10 2 Leucine Rich repeat LRRNT PF01462.13 EMC86764.1 - 4.5e-05 22.7 1.5 4.5e-05 22.7 1.1 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain HemY_N PF07219.8 EMC86764.1 - 0.012 15.1 0.2 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 HemY protein N-terminus UL97 PF06734.7 EMC86764.1 - 0.047 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 UL97 Ni_hydr_CYTB PF01292.15 EMC86764.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Vinculin PF01044.14 EMC86765.1 - 2.7e-15 55.5 0.4 3.2e-15 55.3 0.3 1.0 1 0 0 1 1 1 1 Vinculin family CRISPR_Cse1 PF09481.5 EMC86765.1 - 0.027 13.2 0.1 0.033 12.9 0.1 1.2 1 1 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) CorA PF01544.13 EMC86765.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein 7tm_1 PF00001.16 EMC86767.1 - 5.8e-83 277.9 12.6 7.1e-83 277.6 8.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86767.1 - 6e-18 64.9 6.2 1.1e-17 64.0 4.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC86767.1 - 3e-05 23.2 11.4 3e-05 23.2 7.9 2.0 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Amino_oxidase PF01593.19 EMC86768.1 - 1.6e-81 274.6 0.0 3.7e-81 273.4 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC86768.1 - 2.9e-15 56.0 0.6 7e-15 54.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC86768.1 - 4.6e-07 29.0 0.0 1.1e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC86768.1 - 3.4e-06 27.2 0.3 7.9e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC86768.1 - 4.5e-06 25.7 0.9 6.8e-06 25.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMC86768.1 - 0.00013 22.2 2.8 0.00018 21.8 0.5 2.3 2 1 1 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC86768.1 - 0.00098 19.0 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC86768.1 - 0.0029 16.1 0.4 0.0071 14.8 0.3 1.7 1 1 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EMC86768.1 - 0.0038 16.1 0.7 0.006 15.4 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 EMC86768.1 - 0.0062 16.6 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EMC86768.1 - 0.011 14.8 2.0 0.011 14.8 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EMC86768.1 - 0.017 14.2 0.2 0.042 12.9 0.1 1.6 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 EMC86768.1 - 0.019 14.0 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMC86768.1 - 0.026 14.3 0.3 0.087 12.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FMO-like PF00743.14 EMC86768.1 - 0.041 12.0 0.0 0.061 11.5 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.16 EMC86768.1 - 0.053 13.0 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EMC86768.1 - 0.057 13.2 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 EMC86768.1 - 0.089 11.6 0.6 0.35 9.7 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EMC86768.1 - 0.16 11.5 1.5 2.7 7.6 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RING_2 PF13639.1 EMC86769.1 - 3e-06 26.9 2.0 5.8e-06 26.0 1.4 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 EMC86769.1 - 0.0022 17.6 1.2 0.0034 17.0 0.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 EMC86769.1 - 0.0029 17.2 2.8 0.0056 16.3 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Orthoreo_P10 PF07204.6 EMC86769.1 - 0.022 14.4 0.6 0.032 13.9 0.4 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 zf-RING_5 PF14634.1 EMC86769.1 - 0.027 14.2 2.2 0.044 13.5 1.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF1301 PF06979.7 EMC86769.1 - 0.075 13.1 0.2 0.09 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) zf-C3HC4_3 PF13920.1 EMC86769.1 - 0.1 12.2 2.1 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC86769.1 - 0.35 11.0 2.7 0.61 10.2 1.8 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC86769.1 - 0.99 9.4 6.0 0.12 12.4 1.3 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fumble PF03630.9 EMC86770.1 - 1.1e-93 313.8 0.0 1.2e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Fumble Y_phosphatase PF00102.22 EMC86772.1 - 9.2e-174 574.9 9.8 1.2e-88 296.4 0.4 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EMC86772.1 - 7.7e-10 38.4 0.1 0.00077 19.0 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC86772.1 - 4.3e-08 33.5 1.3 0.002 18.3 0.0 3.0 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC86772.1 - 2e-07 31.1 1.4 0.0023 17.9 0.0 3.2 3 0 0 3 3 3 2 Inositol hexakisphosphate Rifin_STEVOR PF02009.11 EMC86772.1 - 0.0077 15.9 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 EMC86772.1 - 0.016 14.7 0.2 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF912 PF06024.7 EMC86772.1 - 0.024 14.6 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 EMC86772.1 - 0.034 14.5 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 EMC86772.1 - 0.053 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 CD34/Podocalyxin family Tn7_Tnp_TnsA_C PF08721.6 EMC86772.1 - 0.075 13.0 0.0 8.2 6.5 0.0 3.4 3 1 0 3 3 2 0 TnsA endonuclease C terminal TMEM154 PF15102.1 EMC86772.1 - 0.16 11.6 8.8 0.96 9.1 6.1 2.2 1 1 0 1 1 1 0 TMEM154 protein family Y_phosphatase2 PF03162.8 EMC86772.1 - 0.19 11.0 2.1 2.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Tyrosine phosphatase family DUF3149 PF11346.3 EMC86772.1 - 0.35 10.4 2.5 0.84 9.2 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF1180 PF06679.7 EMC86772.1 - 0.37 10.6 15.6 23 4.8 10.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Adeno_E3_CR2 PF02439.10 EMC86772.1 - 2.2 7.9 6.9 2 8.0 1.8 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 MRP-S26 PF14943.1 EMC86774.1 - 2.1e-30 105.4 12.8 2.3e-30 105.3 8.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 MAP7 PF05672.6 EMC86774.1 - 0.052 12.9 17.9 0.059 12.7 12.4 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Tom37_C PF11801.3 EMC86774.1 - 0.062 13.1 3.4 0.073 12.9 2.4 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain ERM PF00769.14 EMC86774.1 - 0.07 12.6 11.7 0.073 12.5 8.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APG6 PF04111.7 EMC86774.1 - 0.16 10.9 9.9 0.17 10.9 6.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF641 PF04859.7 EMC86774.1 - 0.18 11.5 6.4 0.2 11.4 4.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DNA_pol_viral_N PF00242.12 EMC86774.1 - 0.2 10.6 1.7 0.21 10.5 1.2 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2654 PF10849.3 EMC86774.1 - 0.22 11.2 6.1 0.79 9.5 0.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2654) FadA PF09403.5 EMC86774.1 - 0.3 11.1 10.6 0.34 10.9 7.4 1.2 1 0 0 1 1 1 0 Adhesion protein FadA Daxx PF03344.10 EMC86774.1 - 1.1 7.6 7.9 1.2 7.5 5.4 1.0 1 0 0 1 1 1 0 Daxx Family OmpH PF03938.9 EMC86774.1 - 2.6 7.9 8.6 2.9 7.8 6.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 EMC86774.1 - 5.6 5.8 6.5 5.9 5.7 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 EMC86774.1 - 6 5.0 8.1 6.1 5.0 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Hormone_5 PF00184.12 EMC86775.1 - 1.6e-30 105.4 24.6 2.8e-30 104.6 17.0 1.4 1 0 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain Hormone_4 PF00220.12 EMC86775.1 - 0.0012 18.2 5.0 0.0012 18.2 3.5 2.4 2 0 0 2 2 2 1 Neurohypophysial hormones, N-terminal Domain Hormone_5 PF00184.12 EMC86776.1 - 6.9e-31 106.6 26.5 8.7e-31 106.2 18.4 1.1 1 0 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain U-box PF04564.10 EMC86777.1 - 2.4e-26 91.5 0.1 5.7e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.1 EMC86777.1 - 0.00012 21.6 6.4 0.00012 21.6 4.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC86777.1 - 0.00051 19.8 5.4 0.00051 19.8 3.7 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC86777.1 - 0.00092 19.1 6.7 0.00092 19.1 4.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC86777.1 - 0.0014 18.2 5.0 0.0014 18.2 3.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC86777.1 - 0.0077 15.9 4.9 0.04 13.6 0.3 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EMC86777.1 - 0.016 14.8 4.9 0.016 14.8 3.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EMC86777.1 - 0.32 10.9 5.1 1.5 8.7 3.6 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 EMC86777.1 - 0.82 9.6 12.8 0.24 11.3 5.3 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING FAST_1 PF06743.10 EMC86778.1 - 3.8e-17 61.7 0.8 7.3e-16 57.6 0.0 3.4 4 1 1 5 5 5 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 EMC86778.1 - 1.3e-16 60.7 0.0 3e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 RAP PF08373.5 EMC86778.1 - 1.6e-12 47.0 1.1 3.3e-12 46.0 0.8 1.6 1 0 0 1 1 1 1 RAP domain Fez1 PF06818.10 EMC86780.1 - 9.3e-76 254.3 24.4 9.3e-76 254.3 16.9 2.4 2 0 0 2 2 2 1 Fez1 GAS PF13851.1 EMC86780.1 - 1.9 7.6 57.7 2.4 7.3 19.1 3.2 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EMC86780.1 - 10 5.9 58.2 0.11 12.2 11.2 4.4 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DDRGK PF09756.4 EMC86781.1 - 7e-67 224.4 31.9 7e-67 224.4 22.1 1.4 2 0 0 2 2 2 1 DDRGK domain PCI PF01399.22 EMC86781.1 - 8.3e-05 22.8 0.1 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain FeoC PF09012.5 EMC86781.1 - 9.6e-05 22.0 0.2 0.29 10.8 0.0 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator UPF0181 PF03701.9 EMC86781.1 - 0.0045 16.2 0.0 0.023 14.0 0.0 2.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) HTH_DeoR PF08220.7 EMC86781.1 - 0.0073 15.8 0.2 2.3 7.8 0.0 2.4 2 0 0 2 2 2 2 DeoR-like helix-turn-helix domain CAF-1_p150 PF11600.3 EMC86781.1 - 0.18 11.1 44.3 0.25 10.6 30.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BORG_CEP PF14957.1 EMC86781.1 - 1.1 10.1 7.8 2.9 8.8 5.4 1.7 1 0 0 1 1 1 0 Cdc42 effector Cytochrom_C PF00034.16 EMC86781.1 - 1.9 9.3 0.0 1.9 9.3 0.0 3.1 2 1 0 2 2 2 0 Cytochrome c U79_P34 PF03064.11 EMC86781.1 - 6.4 6.2 18.4 11 5.4 12.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HCO3_cotransp PF00955.16 EMC86782.1 - 1.3e-97 327.5 8.1 1.8e-97 327.1 5.6 1.1 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.17 EMC86782.1 - 3e-07 30.2 0.0 1.8e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.8 EMC86782.1 - 4.1e-06 26.4 0.0 1.7e-05 24.4 0.0 1.7 1 1 1 2 2 2 1 Band 3 cytoplasmic domain Sulfate_transp PF00916.15 EMC86782.1 - 0.07 12.1 7.1 3.4 6.5 0.1 3.4 2 1 1 3 3 3 0 Sulfate transporter family Kelch_1 PF01344.20 EMC86784.1 - 2.2e-25 87.9 4.7 2.3e-06 27.0 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 EMC86784.1 - 2.3e-24 84.8 7.4 0.0012 18.5 0.1 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EMC86784.1 - 4.7e-24 83.5 17.3 2.4e-06 27.4 0.0 7.4 8 0 0 8 8 7 5 Kelch motif Kelch_5 PF13854.1 EMC86784.1 - 3.4e-19 68.3 14.6 7.5e-05 22.5 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 EMC86784.1 - 1.1e-18 66.8 1.2 0.0037 17.3 0.0 6.9 6 0 0 6 6 6 6 Galactose oxidase, central domain Lectin_C PF00059.16 EMC86784.1 - 2.3e-17 63.5 0.4 2.3e-17 63.5 0.3 3.4 2 1 1 3 3 1 1 Lectin C-type domain PSI PF01437.20 EMC86784.1 - 6.5e-16 58.2 108.8 2.2e-09 37.3 6.5 7.5 7 0 0 7 7 5 5 Plexin repeat CUB PF00431.15 EMC86784.1 - 8.8e-13 48.2 0.0 3.3e-12 46.4 0.0 2.1 1 0 0 1 1 1 1 CUB domain Kelch_2 PF07646.10 EMC86784.1 - 3.2e-12 45.6 7.6 0.28 11.0 0.0 6.7 6 0 0 6 6 6 4 Kelch motif Rax2 PF12768.2 EMC86784.1 - 0.0014 17.8 1.3 0.051 12.7 0.2 2.4 1 1 1 2 2 2 2 Cortical protein marker for cell polarity Laminin_EGF PF00053.19 EMC86784.1 - 0.0015 18.3 16.5 0.0015 18.3 11.4 8.6 6 3 2 8 8 5 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EMC86784.1 - 0.0085 16.2 10.5 0.0085 16.2 7.3 9.1 8 3 0 8 8 3 2 EGF-like domain GDNF PF02351.11 EMC86785.1 - 5.4e-23 81.3 34.9 1.3e-11 44.8 9.0 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain NIP_1 PF08995.5 EMC86785.1 - 7.1 6.8 18.0 1.8 8.7 0.8 3.6 3 0 0 3 3 3 0 Necrosis inducing protein-1 Reprolysin PF01421.14 EMC86786.1 - 2.5e-69 232.8 0.0 6.2e-69 231.5 0.0 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EMC86786.1 - 5.8e-33 113.4 0.2 9.6e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.7 EMC86786.1 - 8e-31 106.5 10.1 8e-31 106.5 7.0 3.2 3 0 0 3 3 1 1 ADAM cysteine-rich Reprolysin_5 PF13688.1 EMC86786.1 - 2.4e-25 89.6 0.7 2.4e-25 89.6 0.5 2.3 3 0 0 3 3 2 1 Metallo-peptidase family M12 Disintegrin PF00200.18 EMC86786.1 - 5.1e-25 87.4 27.0 5.1e-25 87.4 18.7 4.2 3 1 0 3 3 2 1 Disintegrin Reprolysin_3 PF13582.1 EMC86786.1 - 7.3e-19 68.5 0.1 2.4e-18 66.8 0.0 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC86786.1 - 1.4e-18 67.5 0.2 2.8e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC86786.1 - 1.9e-15 56.9 0.2 3.3e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 EMC86786.1 - 0.00056 20.0 12.9 0.00056 20.0 8.9 5.5 4 1 0 4 4 2 1 EGF-like domain Peptidase_M43 PF05572.8 EMC86786.1 - 0.0015 18.1 0.4 0.8 9.2 0.0 2.5 2 0 0 2 2 2 2 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.6 EMC86786.1 - 0.052 13.3 0.3 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M10 PF00413.19 EMC86786.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 EMC86786.1 - 0.074 11.9 0.3 0.14 11.0 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 ALMS_motif PF15309.1 EMC86787.1 - 4e-35 120.6 12.2 4.4e-35 120.5 8.4 1.0 1 0 0 1 1 1 1 ALMS motif DUF2782 PF11191.3 EMC86787.1 - 0.093 12.7 0.2 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Hemolysin_N PF12563.3 EMC86788.1 - 0.24 10.7 1.2 5.2 6.4 0.1 2.3 2 0 0 2 2 2 0 Hemolytic toxin N terminal RRM_1 PF00076.17 EMC86791.1 - 3e-34 116.4 0.0 6.4e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC86791.1 - 1.9e-25 88.6 0.1 6.3e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC86791.1 - 1.1e-20 73.1 0.1 3.3e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EMC86791.1 - 3e-08 33.1 3.6 5.4e-08 32.4 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Calcipressin PF04847.7 EMC86791.1 - 7.1e-05 22.4 0.1 0.14 11.7 0.0 2.1 1 1 1 2 2 2 2 Calcipressin zf-CCHC_3 PF13917.1 EMC86791.1 - 0.0015 18.2 0.5 0.0028 17.3 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF3791 PF12668.2 EMC86791.1 - 0.0067 16.0 0.7 0.57 9.8 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3791) Limkain-b1 PF11608.3 EMC86791.1 - 0.0088 15.7 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 DbpA PF03880.10 EMC86791.1 - 0.0093 15.6 0.0 0.49 10.0 0.0 2.3 2 0 0 2 2 2 1 DbpA RNA binding domain RNA_bind PF08675.6 EMC86791.1 - 0.016 15.1 0.1 9.5 6.2 0.0 3.1 2 1 1 3 3 3 0 RNA binding domain OxoDH_E1alpha_N PF12573.3 EMC86791.1 - 0.042 13.4 0.2 0.096 12.2 0.0 1.6 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal zf-CCHC_5 PF14787.1 EMC86791.1 - 0.23 10.9 5.4 0.41 10.1 3.7 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Lectin_C PF00059.16 EMC86793.1 - 1.5e-06 28.8 0.1 2.8e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 EMC86793.1 - 0.12 11.8 0.2 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 UL45 protein Lectin_C PF00059.16 EMC86795.1 - 1.6e-17 64.0 0.3 3.1e-17 63.1 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain PMP22_Claudin PF00822.15 EMC86796.1 - 4.6e-44 149.9 19.0 5.3e-44 149.8 13.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC86796.1 - 6.6e-07 29.1 22.5 1e-06 28.5 13.2 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 EMC86796.1 - 3.1e-05 23.6 15.9 5.9e-05 22.7 11.0 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF998 PF06197.8 EMC86796.1 - 0.00036 19.8 2.1 0.00036 19.8 1.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF998) DUF1422 PF07226.6 EMC86796.1 - 0.0018 18.0 2.8 0.0018 18.0 1.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1422) L_HGMIC_fpl PF10242.4 EMC86796.1 - 0.065 13.2 16.3 0.11 12.4 11.2 1.5 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF2615 PF11027.3 EMC86796.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2615) DUF4064 PF13273.1 EMC86796.1 - 0.17 12.0 19.2 0.39 10.8 7.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Claudin_3 PF06653.6 EMC86796.1 - 0.23 11.1 21.6 0.61 9.8 14.9 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like ABC2_membrane_5 PF13346.1 EMC86796.1 - 0.31 10.3 19.3 0.013 14.8 6.3 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein MIG-14_Wnt-bd PF06664.7 EMC86796.1 - 0.75 8.5 13.6 1.3 7.7 9.4 1.6 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Virul_fac_BrkB PF03631.10 EMC86796.1 - 0.88 8.8 14.3 1.1 8.5 9.9 1.2 1 0 0 1 1 1 0 Virulence factor BrkB MARVEL PF01284.18 EMC86796.1 - 2.9 7.7 22.2 11 5.8 8.9 2.8 1 1 1 2 2 2 0 Membrane-associating domain UbiA PF01040.13 EMC86796.1 - 3 7.0 14.5 0.029 13.5 4.2 1.7 2 0 0 2 2 2 0 UbiA prenyltransferase family DUF1218 PF06749.7 EMC86796.1 - 9.4 6.7 23.5 5.6 7.5 3.7 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) Pox_P21 PF05313.7 EMC86796.1 - 9.5 5.4 8.9 0.3 10.3 1.1 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein 7TMR-DISM_7TM PF07695.6 EMC86796.1 - 9.6 5.8 29.3 19 4.8 2.5 2.8 1 1 1 2 2 2 0 7TM diverse intracellular signalling GSG-1 PF07803.6 EMC86797.1 - 1.1e-48 163.6 0.0 2e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 EMC86797.1 - 9.2e-09 35.2 0.8 1.7e-08 34.3 0.5 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC86797.1 - 1.5e-08 34.4 3.1 2.9e-08 33.5 2.1 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.6 EMC86797.1 - 0.00048 19.8 1.3 0.03 14.0 0.5 2.2 2 0 0 2 2 2 1 Tight junction protein, Claudin-like L_HGMIC_fpl PF10242.4 EMC86797.1 - 0.0021 18.1 3.8 0.013 15.5 2.6 2.0 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 EMC86797.1 - 0.037 13.2 7.1 0.89 8.7 0.0 2.8 3 0 0 3 3 3 0 Clc-like PQQ_2 PF13360.1 EMC86798.1 - 2.1e-07 30.6 0.1 0.0043 16.5 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.18 EMC86798.1 - 2.8e-07 30.0 1.9 0.0014 18.2 0.0 3.0 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 EMC86798.1 - 2.7e-06 27.6 0.1 0.045 14.1 0.0 3.1 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EMC86798.1 - 0.031 13.7 0.2 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region DUF1409 PF07197.7 EMC86799.1 - 0.012 15.6 0.1 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) HxlR PF01638.12 EMC86799.1 - 0.084 12.5 2.9 0.11 12.1 0.6 2.0 2 0 0 2 2 2 0 HxlR-like helix-turn-helix FlaC_arch PF05377.6 EMC86799.1 - 0.092 12.6 0.8 0.19 11.6 0.5 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) GSCFA PF08885.6 EMC86799.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 GSCFA family HALZ PF02183.13 EMC86799.1 - 0.16 11.7 0.8 0.42 10.3 0.4 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper Uds1 PF15456.1 EMC86799.1 - 3.4 7.6 5.2 24 4.9 3.6 2.0 1 1 0 1 1 1 0 Up-regulated During Septation SOUL PF04832.7 EMC86800.1 - 1.4e-43 148.4 0.0 1.5e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein 7tm_3 PF00003.17 EMC86801.1 - 2.6e-33 115.3 28.0 3.2e-33 115.0 19.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1772 PF08592.6 EMC86801.1 - 0.024 14.3 0.4 0.024 14.3 0.3 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF1345 PF07077.6 EMC86801.1 - 0.12 11.9 11.7 1.3 8.5 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) Tmpp129 PF10272.4 EMC86801.1 - 0.14 10.8 1.4 0.2 10.3 1.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor 7TMR-DISM_7TM PF07695.6 EMC86801.1 - 3.5 7.2 34.3 21 4.6 23.7 2.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling DEAD PF00270.24 EMC86802.1 - 3.4e-46 156.8 0.2 5.6e-46 156.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC86802.1 - 6.5e-29 99.6 0.2 2.1e-27 94.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC86802.1 - 0.00024 20.9 0.0 0.00078 19.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ApoL PF05461.6 EMC86803.1 - 4.2e-21 75.5 1.3 6.9e-21 74.8 0.1 1.7 2 0 0 2 2 2 1 Apolipoprotein L SseC PF04888.7 EMC86803.1 - 0.00026 20.4 1.1 0.004 16.5 0.2 2.0 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Serum_albumin PF00273.15 EMC86803.1 - 0.015 14.7 0.9 0.034 13.5 0.7 1.5 1 1 0 1 1 1 0 Serum albumin family DUF4231 PF14015.1 EMC86803.1 - 0.099 12.6 0.4 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Snapin_Pallidin PF14712.1 EMC86803.1 - 0.17 12.1 1.6 7.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.12 EMC86803.1 - 0.31 10.6 2.0 8.9 5.9 0.0 2.5 3 0 0 3 3 3 0 Prefoldin subunit Histone PF00125.19 EMC86804.1 - 3.5e-27 94.3 0.0 4.5e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86804.1 - 3.2e-05 23.9 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC86805.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86805.1 - 9.7e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC86805.1 - 0.0024 18.0 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 EMC86805.1 - 0.059 12.8 0.2 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 EMC86806.1 - 3.9e-26 90.9 0.1 5.5e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86806.1 - 1.1e-06 28.5 1.2 2.1e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC86806.1 - 0.0026 18.0 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 EMC86806.1 - 0.099 12.0 0.2 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 EMC86807.1 - 4.4e-27 94.0 0.0 5.7e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86807.1 - 3.9e-05 23.6 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC86808.1 - 3.5e-26 91.1 0.1 4.9e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86808.1 - 1.3e-06 28.3 1.6 1.9e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC86808.1 - 0.0023 18.1 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EMC86809.1 - 4.4e-27 94.0 0.0 5.7e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86809.1 - 3.9e-05 23.6 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC86810.1 - 4.8e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86810.1 - 1.2e-06 28.4 0.9 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC86810.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EMC86811.1 - 4.1e-27 94.1 0.0 5.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86811.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Linker_histone PF00538.14 EMC86812.1 - 1.2e-22 79.7 2.4 2.7e-22 78.6 1.6 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Histone PF00125.19 EMC86813.1 - 5.9e-15 55.1 0.1 7.2e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC86813.1 - 1.5e-05 25.0 0.1 2e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EMC86813.1 - 3.4e-05 23.6 0.2 4.7e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMC86813.1 - 0.00024 21.1 0.1 0.00038 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC86813.1 - 0.016 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMC86813.1 - 0.019 14.2 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC86813.1 - 0.041 13.6 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EMC86814.1 - 3.9e-27 94.1 0.0 5e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86814.1 - 3.5e-05 23.7 0.0 4.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC86815.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC86815.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC86815.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EMC86815.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EMC86816.1 - 4.1e-27 94.1 0.0 5.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC86816.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC86817.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC86817.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EMC86817.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMC86817.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC86817.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMC86817.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC86817.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit 7tm_1 PF00001.16 EMC86818.1 - 2.5e-66 223.4 22.0 3.3e-66 223.0 15.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86818.1 - 1.1e-10 41.1 22.4 1.5e-10 40.6 15.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC86818.1 - 1.2e-07 31.1 17.7 1.2e-07 31.1 12.3 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC86818.1 - 4.4e-05 22.7 18.3 4.4e-05 22.7 12.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx EVC2_like PF12297.3 EMC86818.1 - 0.00048 18.8 0.4 0.018 13.7 0.0 2.0 2 0 0 2 2 2 2 Ellis van Creveld protein 2 like protein Herpes_US9 PF06072.6 EMC86818.1 - 0.12 12.1 0.2 0.12 12.1 0.1 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 7tm_1 PF00001.16 EMC86819.1 - 8e-56 189.0 23.0 9.6e-56 188.7 16.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86819.1 - 1.1e-11 44.3 21.0 1.6e-11 43.8 14.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC86819.1 - 6.3e-07 28.8 13.1 6.3e-07 28.8 9.1 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv SK_channel PF03530.9 EMC86819.1 - 0.085 12.6 6.9 0.42 10.4 4.8 2.2 1 1 0 1 1 1 0 Calcium-activated SK potassium channel PSP1 PF04468.7 EMC86820.1 - 0.018 15.0 0.3 0.053 13.5 0.1 1.9 2 0 0 2 2 2 0 PSP1 C-terminal conserved region ATG11 PF10377.4 EMC86821.1 - 6.4e-28 97.2 0.0 6.4e-28 97.2 0.0 4.3 4 1 1 5 5 5 1 Autophagy-related protein 11 MYT1 PF08474.6 EMC86822.1 - 9.9e-96 320.1 9.7 9.9e-96 320.1 6.7 2.6 2 0 0 2 2 2 1 Myelin transcription factor 1 zf-C2HC PF01530.13 EMC86822.1 - 2e-91 299.2 66.7 4.7e-17 61.3 3.3 6.6 6 0 0 6 6 6 6 Zinc finger, C2HC type DUF1664 PF07889.7 EMC86822.1 - 0.0023 17.7 0.2 0.0072 16.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF342 PF03961.8 EMC86822.1 - 0.095 11.1 5.4 0.19 10.1 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Sina PF03145.11 EMC86822.1 - 0.11 12.1 3.1 0.79 9.3 0.4 2.6 2 0 0 2 2 2 0 Seven in absentia protein family DivIC PF04977.10 EMC86822.1 - 3.8 7.0 7.8 2.5 7.6 3.0 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EMC86822.1 - 4.1 7.8 13.8 0.036 14.4 2.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EMC86822.1 - 7 4.3 13.7 0.25 9.1 2.5 2.5 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family IBR PF01485.16 EMC86822.1 - 7.4 6.5 19.7 43 4.0 0.0 6.3 5 2 1 6 6 6 0 IBR domain PCMT PF01135.14 EMC86823.1 - 2.4e-28 99.0 0.0 3.4e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.11 EMC86823.1 - 1.7e-06 27.7 3.1 0.003 17.3 0.7 2.7 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.8 EMC86823.1 - 0.00012 21.4 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EMC86823.1 - 0.00031 21.3 0.0 0.0006 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC86823.1 - 0.00036 20.1 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EMC86823.1 - 0.0053 16.2 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Septin PF00735.13 EMC86824.1 - 2.1e-128 427.2 0.4 2.9e-128 426.7 0.3 1.1 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 EMC86824.1 - 6.5e-07 28.6 0.0 1.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMC86824.1 - 9.2e-07 28.8 0.1 1.9e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC86824.1 - 3.5e-05 23.3 0.0 0.017 14.5 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EMC86824.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_10 PF12846.2 EMC86824.1 - 0.0041 16.5 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EMC86824.1 - 0.008 16.5 0.2 0.038 14.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain Ras PF00071.17 EMC86824.1 - 0.011 15.1 0.1 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.18 EMC86824.1 - 0.014 15.1 4.9 0.22 11.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 EMC86824.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EMC86824.1 - 0.031 14.4 0.2 0.15 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EMC86824.1 - 0.04 13.4 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EMC86824.1 - 0.056 13.9 0.1 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EMC86824.1 - 0.067 12.6 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EMC86824.1 - 0.072 13.3 1.2 0.12 12.6 0.1 2.0 2 1 0 2 2 2 0 ABC transporter LRR_8 PF13855.1 EMC86825.1 - 3.3e-07 29.9 0.0 6.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRRNT PF01462.13 EMC86825.1 - 1.7e-05 24.1 2.1 1.7e-05 24.1 1.4 2.9 3 1 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 EMC86825.1 - 0.00016 21.1 0.1 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC86825.1 - 0.0012 18.5 0.4 0.11 12.6 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich Repeat LRRCT PF01463.19 EMC86825.1 - 0.037 14.2 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain T-box PF00907.17 EMC86826.1 - 1.2e-66 223.7 0.3 1.4e-66 223.5 0.2 1.0 1 0 0 1 1 1 1 T-box WD40 PF00400.27 EMC86827.1 - 5.1e-25 86.4 3.0 3.7e-07 29.7 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EMC86827.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pyr_redox_2 PF07992.9 EMC86828.1 - 4.2e-36 124.7 0.0 1.5e-35 122.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMC86828.1 - 1.7e-30 105.2 0.0 3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMC86828.1 - 1.1e-11 44.9 0.3 5e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMC86828.1 - 7.8e-08 31.5 4.9 7.1e-07 28.4 0.5 2.8 2 2 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EMC86828.1 - 1.1e-05 24.0 0.9 0.0003 19.4 0.1 2.4 2 1 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMC86828.1 - 2.8e-05 23.3 0.1 4.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EMC86828.1 - 5.9e-05 22.0 1.4 0.00041 19.3 1.0 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EMC86828.1 - 6.9e-05 21.9 0.0 0.075 11.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EMC86828.1 - 0.00019 20.6 0.2 0.00032 19.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC86828.1 - 0.0006 19.7 0.4 0.0016 18.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC86828.1 - 0.00076 18.4 1.7 0.0014 17.6 0.3 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC86828.1 - 0.0013 18.8 0.1 0.0048 16.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1775 PF07987.6 EMC86828.1 - 0.021 14.6 0.4 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) MOZART2 PF12926.2 EMC86828.1 - 0.049 13.2 0.0 1.6 8.3 0.0 2.9 4 0 0 4 4 4 0 Mitotic-spindle organizing gamma-tubulin ring associated Nup35_RRM_2 PF14605.1 EMC86828.1 - 0.079 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Lycopene_cycl PF05834.7 EMC86828.1 - 0.13 11.1 0.6 0.4 9.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_3 PF01596.12 EMC86829.1 - 9.9e-23 80.2 0.0 1.5e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMC86829.1 - 3.2e-13 50.4 0.0 4.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC86829.1 - 4.7e-08 33.5 0.0 8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC86829.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC86829.1 - 2.6e-05 23.8 0.0 6.7e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.7 EMC86829.1 - 0.00054 19.3 0.0 0.0011 18.3 0.0 1.5 1 1 1 2 2 2 1 Cephalosporin hydroxylase PCMT PF01135.14 EMC86829.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1188 PF06690.6 EMC86829.1 - 0.064 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Cons_hypoth95 PF03602.10 EMC86829.1 - 0.076 12.3 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 GCD14 PF08704.5 EMC86829.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Arm PF00514.18 EMC86830.1 - 4.4e-36 121.4 1.8 1.3e-07 31.1 0.0 7.5 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC86830.1 - 7.9e-16 58.1 3.2 4.5e-08 33.2 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats Arm_2 PF04826.8 EMC86830.1 - 2.7e-09 36.5 0.2 0.00036 19.7 0.0 4.1 2 2 1 4 4 4 2 Armadillo-like HEAT PF02985.17 EMC86830.1 - 3.2e-08 32.9 0.5 0.61 10.3 0.1 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EMC86830.1 - 6e-07 29.7 2.0 0.45 11.0 0.1 5.8 6 0 0 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 EMC86830.1 - 0.0049 16.5 0.2 0.14 11.9 0.0 3.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain G6PD_C PF02781.11 EMC86830.1 - 0.075 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain RICTOR_V PF14668.1 EMC86830.1 - 0.14 12.1 0.1 0.7 9.8 0.0 2.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 NRDE PF05742.7 EMC86831.1 - 1.6e-10 40.8 0.0 1.6e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 NRDE protein dsrm PF00035.20 EMC86832.1 - 5.9e-20 71.6 4.3 3.4e-12 46.7 0.0 3.9 3 1 0 3 3 3 2 Double-stranded RNA binding motif Ran_BP1 PF00638.13 EMC86833.1 - 2.3e-54 182.6 0.4 2.3e-54 182.6 0.3 1.9 2 0 0 2 2 2 1 RanBP1 domain DUF1681 PF07933.9 EMC86833.1 - 0.0078 15.7 0.7 0.011 15.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PKI PF02827.11 EMC86833.1 - 0.019 15.0 4.7 0.019 15.0 3.3 1.9 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor DUF883 PF05957.8 EMC86833.1 - 0.028 14.8 2.7 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) His_Phos_1 PF00300.17 EMC86834.1 - 3.4e-18 66.2 0.7 4.5e-17 62.5 0.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CUB PF00431.15 EMC86835.1 - 2.3e-20 72.6 0.1 6.2e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 CUB domain Kringle PF00051.13 EMC86835.1 - 2.8e-19 68.9 7.3 6.4e-19 67.8 5.1 1.7 1 0 0 1 1 1 1 Kringle domain WSC PF01822.14 EMC86835.1 - 1.1e-18 66.9 9.7 1.1e-18 66.9 6.8 1.9 2 0 0 2 2 2 1 WSC domain zf-RING_2 PF13639.1 EMC86836.1 - 3.2e-07 30.0 9.0 3.2e-07 30.0 6.3 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EMC86836.1 - 0.00064 19.3 5.4 0.00064 19.3 3.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC86836.1 - 0.001 19.1 7.9 0.001 19.1 5.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC86836.1 - 0.0022 17.9 5.5 0.0022 17.9 3.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC86836.1 - 0.0073 15.9 5.1 0.0073 15.9 3.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.17 EMC86837.1 - 0.048 13.3 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 PA domain HSCB_C PF07743.8 EMC86840.1 - 8.3e-16 58.2 8.6 1.4e-15 57.5 6.0 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EMC86840.1 - 0.011 15.3 2.0 0.056 13.1 0.0 2.8 2 1 0 2 2 2 0 DnaJ domain UCH PF00443.24 EMC86840.1 - 0.016 14.3 2.2 0.016 14.3 1.5 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CDC37_C PF08564.5 EMC86840.1 - 0.046 13.5 2.1 0.09 12.6 0.2 2.1 1 1 1 2 2 2 0 Cdc37 C terminal domain FliT PF05400.8 EMC86840.1 - 0.071 13.5 1.6 0.13 12.7 1.0 1.6 1 1 0 1 1 1 0 Flagellar protein FliT TRM PF02005.11 EMC86840.1 - 0.22 10.4 1.5 0.27 10.0 1.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Spectrin PF00435.16 EMC86840.1 - 1.2 9.4 6.6 1.1 9.5 3.1 2.0 2 1 0 2 2 2 0 Spectrin repeat cwf21 PF08312.7 EMC86840.1 - 4.6 7.1 8.9 0.52 10.2 2.6 2.0 2 1 0 2 2 2 0 cwf21 domain Pkinase PF00069.20 EMC86841.1 - 3.1e-73 246.1 0.0 4.2e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86841.1 - 2.3e-32 112.0 0.0 3.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMC86841.1 - 7.6e-13 48.3 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EMC86841.1 - 1.2e-07 30.9 0.0 2.3e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EMC86841.1 - 0.0046 15.8 0.1 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 EMC86841.1 - 0.024 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMC86841.1 - 0.025 13.9 0.1 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EMC86841.1 - 0.045 12.8 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Perm-CXXC PF15629.1 EMC86842.1 - 0.043 13.8 1.0 0.073 13.0 0.7 1.4 1 0 0 1 1 1 0 Permuted single zf-CXXC unit IP_trans PF02121.13 EMC86843.1 - 1.2e-135 450.5 2.9 1.4e-135 450.3 2.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Crystall PF00030.14 EMC86845.1 - 5.6e-53 176.7 4.2 5.6e-27 93.4 0.6 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall PF00030.14 EMC86846.1 - 1.3e-59 198.0 3.5 5.4e-29 99.9 0.3 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EMC86846.1 - 1.5e-06 27.8 0.2 0.012 15.3 0.0 2.9 2 2 1 3 3 3 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.8 EMC86846.1 - 0.013 15.8 0.1 1.6 9.1 0.0 2.4 1 1 1 2 2 2 0 Peptidase inhibitor family I36 GCFC PF07842.7 EMC86848.1 - 5.7e-98 327.6 16.2 1.9e-97 325.9 9.7 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EMC86848.1 - 1.3e-25 89.5 9.1 1.3e-25 89.5 6.3 1.7 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EMC86848.1 - 4.4e-16 58.3 4.7 8.5e-16 57.4 3.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC86848.1 - 0.0024 17.6 1.0 0.0024 17.6 0.7 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site SRR1 PF07985.7 EMC86849.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 SRR1 Asp_Arg_Hydrox PF05118.10 EMC86851.1 - 2e-32 112.2 0.0 2.7e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sushi PF00084.15 EMC86852.1 - 1.2e-43 147.2 26.7 6.9e-10 39.1 1.3 5.4 5 0 0 5 5 5 5 Sushi domain (SCR repeat) CUB PF00431.15 EMC86852.1 - 2.7e-40 136.8 0.0 4.2e-19 68.6 0.0 3.6 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.15 EMC86852.1 - 2.5e-05 23.7 0.0 0.43 10.1 0.0 3.4 3 0 0 3 3 3 3 CUB-like domain Pkinase PF00069.20 EMC86853.1 - 1.3e-70 237.5 0.0 5.4e-70 235.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86853.1 - 9.8e-29 100.1 0.0 1.6e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EMC86853.1 - 6.4e-19 68.1 2.9 1.2e-18 67.3 2.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.24 EMC86853.1 - 1.5e-10 41.2 0.2 3.4e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EMC86853.1 - 0.00065 18.7 0.0 0.00099 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC86853.1 - 0.03 13.4 0.1 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 EMC86853.1 - 0.22 11.8 3.4 0.3 11.3 0.3 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Crystall PF00030.14 EMC86854.1 - 4.4e-42 141.8 3.4 6.2e-30 102.9 0.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EMC86854.1 - 0.00055 19.6 1.2 0.0028 17.3 0.2 2.3 2 1 0 2 2 2 1 Beta/Gamma crystallin Crystall PF00030.14 EMC86855.1 - 9.3e-57 188.8 0.3 2.2e-27 94.7 0.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EMC86855.1 - 0.0032 17.1 0.0 5.7 6.7 0.0 3.1 2 1 0 3 3 3 2 Beta/Gamma crystallin Tankyrase_bdg_C PF15327.1 EMC86856.1 - 7.3e-62 208.6 16.9 7.3e-62 208.6 11.7 6.6 7 2 1 8 8 8 1 Tankyrase binding protein C terminal domain SNF PF00209.13 EMC86858.1 - 4.8e-142 474.0 19.9 5.4e-142 473.9 13.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GPCR_chapero_1 PF11904.3 EMC86860.1 - 9.3e-105 350.1 0.6 2.1e-104 348.9 0.0 1.7 2 0 0 2 2 2 1 GPCR-chaperone Ank_2 PF12796.2 EMC86860.1 - 9.8e-14 51.4 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86860.1 - 5.4e-13 48.0 0.0 4.2e-06 26.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMC86860.1 - 2.9e-11 43.5 0.0 1e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC86860.1 - 7.9e-11 41.8 0.0 7.1e-08 32.4 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86860.1 - 3.7e-10 39.0 0.0 0.001 19.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat UIM PF02809.15 EMC86860.1 - 0.033 13.7 14.9 0.34 10.5 1.5 3.7 3 0 0 3 3 3 0 Ubiquitin interaction motif RNA_pol_Rbc25 PF08292.7 EMC86860.1 - 0.15 12.2 1.5 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 GIT1_C PF12205.3 EMC86861.1 - 1e-59 199.7 3.9 2.9e-59 198.2 2.7 1.8 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.6 EMC86861.1 - 1.4e-31 107.4 2.0 2.4e-15 55.5 0.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.13 EMC86861.1 - 4.6e-22 78.0 0.1 4.6e-22 78.0 0.0 2.3 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EMC86861.1 - 5.9e-15 55.3 0.0 2.9e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86861.1 - 2.9e-09 36.2 0.5 9.2e-05 22.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EMC86861.1 - 5.1e-09 36.4 0.0 0.00017 22.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC86861.1 - 2e-08 34.1 0.1 1.6e-07 31.3 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC86861.1 - 0.0005 20.0 0.0 0.46 10.8 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat DUF4319 PF14203.1 EMC86861.1 - 0.014 14.9 0.1 0.071 12.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) DUF3347 PF11827.3 EMC86861.1 - 0.41 10.6 6.2 1.3 8.9 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Trichoplein PF13868.1 EMC86862.1 - 5.2e-11 41.5 119.9 5.7e-11 41.4 83.1 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin GLTP PF08718.6 EMC86863.1 - 5.7e-31 107.5 0.0 7.7e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GN3L_Grn1 PF08701.6 EMC86863.1 - 0.074 12.9 0.3 0.074 12.9 0.2 1.6 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Uso1_p115_head PF04869.9 EMC86863.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Ank_2 PF12796.2 EMC86864.1 - 1.1e-14 54.5 0.2 2.2e-05 24.6 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMC86864.1 - 2.6e-14 52.2 0.1 1.6e-06 27.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EMC86864.1 - 3.3e-12 45.3 0.1 0.00022 21.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMC86864.1 - 5.1e-12 45.6 0.1 0.0028 17.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ion_trans PF00520.26 EMC86864.1 - 1.7e-07 30.7 19.7 3e-07 29.8 13.2 1.7 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.1 EMC86864.1 - 1.7e-07 31.5 0.3 0.044 14.3 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF4065 PF13274.1 EMC86864.1 - 0.034 14.8 0.0 0.074 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) YbhQ PF11076.3 EMC86864.1 - 1.5 8.4 6.3 0.6 9.7 1.0 2.4 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ FAM222A PF15258.1 EMC86865.1 - 2.7e-120 402.9 10.4 6.9e-64 216.8 2.4 2.1 1 1 1 2 2 2 2 Protein family of FAM222A Cob_adeno_trans PF01923.13 EMC86866.1 - 1.1e-41 142.2 0.0 1.3e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase T2SF PF00482.18 EMC86866.1 - 0.037 13.9 0.0 0.086 12.7 0.0 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF2737 PF10930.3 EMC86866.1 - 0.16 11.6 0.0 5.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) HECT PF00632.20 EMC86867.1 - 7.8e-92 307.8 0.0 1.8e-91 306.6 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EMC86867.1 - 0.00025 20.3 2.2 0.00095 18.6 1.5 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_TH1 PF06017.8 EMC86868.1 - 3.5e-35 121.1 1.4 4.1e-35 120.9 1.0 1.1 1 0 0 1 1 1 1 Myosin tail Fork_head PF00250.13 EMC86869.1 - 1.5e-30 105.0 0.4 2.6e-30 104.2 0.2 1.3 1 0 0 1 1 1 1 Fork head domain UDG PF03167.14 EMC86870.1 - 6.8e-29 100.2 0.0 1.1e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sugar_tr PF00083.19 EMC86871.1 - 1.4e-37 129.3 28.4 5.3e-25 87.9 7.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC86871.1 - 5.1e-36 124.1 38.3 2e-21 76.0 15.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC86871.1 - 1.5 7.1 27.6 0.11 10.8 2.2 3.8 3 1 1 4 4 4 0 MFS/sugar transport protein Transformer PF06495.6 EMC86872.1 - 0.015 15.1 4.3 0.018 14.9 3.0 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein DUF1900 PF08954.6 EMC86873.1 - 4.4e-58 194.6 0.0 1.3e-57 193.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EMC86873.1 - 4.2e-35 119.2 0.1 7.7e-35 118.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EMC86873.1 - 4.6e-24 83.3 6.9 1.3e-09 37.5 0.4 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 EMC86873.1 - 0.0079 15.9 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF4094 PF13334.1 EMC86873.1 - 0.53 10.7 3.0 1.2 9.5 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CDP-OH_P_transf PF01066.16 EMC86875.1 - 0.0078 16.4 0.3 0.01 16.0 0.2 1.1 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase TMEM154 PF15102.1 EMC86875.1 - 0.027 14.1 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family LSR PF05624.9 EMC86875.1 - 0.054 13.2 0.4 0.078 12.7 0.3 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) NifU_N PF01592.11 EMC86876.1 - 2.6e-52 176.0 0.1 3e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Jag_N PF14804.1 EMC86876.1 - 0.03 14.3 0.9 3.6 7.6 0.0 2.5 3 0 0 3 3 3 0 Jag N-terminus CO_deh_flav_C PF03450.12 EMC86876.1 - 0.08 12.8 0.2 0.64 9.9 0.0 2.0 1 1 1 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain RRM_1 PF00076.17 EMC86877.1 - 3.6e-32 109.7 0.1 2.4e-17 62.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC86877.1 - 1.6e-24 85.6 0.0 5.7e-13 48.6 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC86877.1 - 4.7e-14 51.9 0.1 1.5e-05 24.7 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EMC86877.1 - 1.3e-05 24.3 1.5 3.8e-05 22.9 1.0 1.9 1 0 0 1 1 1 1 Lsm interaction motif DUF1993 PF09351.5 EMC86877.1 - 0.032 14.1 2.4 8.6 6.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) Nup35_RRM_2 PF14605.1 EMC86877.1 - 0.11 12.2 0.0 8.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TMCO5 PF14992.1 EMC86877.1 - 0.51 9.4 12.1 9.8 5.2 6.1 2.8 2 0 0 2 2 2 0 TMCO5 family DUF908 PF06012.7 EMC86877.1 - 0.58 9.4 4.3 12 5.1 1.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) TPR_14 PF13428.1 EMC86877.1 - 2.3 9.0 14.9 21 6.1 0.2 6.7 7 1 1 8 8 8 0 Tetratricopeptide repeat Fic PF02661.13 EMC86878.1 - 4e-28 97.9 0.1 8.3e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family TPR_11 PF13414.1 EMC86878.1 - 8.7e-05 22.0 1.0 0.0026 17.3 0.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC86878.1 - 0.00082 19.1 0.7 0.018 14.9 0.3 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86878.1 - 0.03 14.4 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86878.1 - 0.07 13.8 0.2 0.24 12.1 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86878.1 - 0.082 12.8 0.7 4.4 7.3 0.0 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC86878.1 - 0.58 9.8 2.5 6.4 6.5 0.5 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Sulfotransfer_1 PF00685.22 EMC86879.1 - 9.7e-06 25.0 0.0 3e-05 23.4 0.0 1.8 1 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC86879.1 - 0.0021 19.0 0.1 0.0027 18.6 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family C2 PF00168.25 EMC86881.1 - 5.4e-47 157.5 0.0 6.4e-23 80.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 EMC86881.1 - 2.6e-35 120.8 7.9 2.6e-35 120.8 5.4 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger zf-piccolo PF05715.8 EMC86881.1 - 0.056 13.4 10.6 0.16 12.0 5.8 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger C1_1 PF00130.17 EMC86881.1 - 3.1 7.6 12.9 0.33 10.7 5.1 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Y_phosphatase PF00102.22 EMC86882.1 - 6.4e-84 280.9 1.4 9.2e-84 280.4 0.5 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase SH2 PF00017.19 EMC86882.1 - 1.4e-49 165.7 0.1 2.4e-23 81.7 0.0 2.7 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.15 EMC86882.1 - 1.6e-05 24.5 1.3 7e-05 22.4 0.0 2.7 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMC86882.1 - 0.004 17.2 4.9 0.0046 17.0 0.0 2.9 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC86882.1 - 0.0044 17.2 0.1 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF1092 PF06485.6 EMC86882.1 - 0.047 12.6 0.7 0.088 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1092) Ribosomal_L6e PF01159.14 EMC86883.1 - 2e-41 140.6 1.3 2e-41 140.6 0.9 2.4 3 0 0 3 3 3 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EMC86883.1 - 7.2e-24 83.4 12.6 7.2e-24 83.4 8.8 3.1 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain NatB_MDM20 PF09797.4 EMC86884.1 - 8.7e-107 356.9 1.4 8.7e-107 356.9 1.0 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 EMC86884.1 - 5e-06 26.6 3.9 0.91 10.3 0.0 6.2 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86884.1 - 1.2e-05 25.7 4.2 0.014 16.0 0.2 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86884.1 - 0.0034 17.6 8.2 0.43 10.9 0.3 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EMC86884.1 - 0.0099 16.1 0.9 0.17 12.1 0.3 3.0 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_2 PF07719.12 EMC86884.1 - 0.12 12.3 3.2 12 6.1 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3510 PF12022.3 EMC86884.1 - 0.19 11.8 3.5 0.42 10.7 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) TPR_11 PF13414.1 EMC86884.1 - 0.31 10.6 9.8 1.9 8.2 0.1 4.3 3 1 2 5 5 5 0 TPR repeat ERp29_N PF07912.8 EMC86885.1 - 3.8e-44 149.6 0.5 6.1e-44 149.0 0.3 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.7 EMC86885.1 - 2.9e-16 59.8 4.5 5.2e-16 59.0 3.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain PRTase_1 PF11202.3 EMC86885.1 - 0.0037 16.2 1.9 0.0057 15.6 1.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase (PRTase) Git3_C PF11970.3 EMC86886.1 - 9.7e-05 22.0 2.4 0.00028 20.5 1.6 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EMC86886.1 - 0.088 11.9 9.9 0.52 9.4 6.8 2.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Reprolysin PF01421.14 EMC86887.1 - 1e-52 178.6 0.3 1e-52 178.6 0.2 1.6 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC86887.1 - 3.2e-35 120.7 6.3 3.2e-35 120.7 4.4 3.5 4 1 0 4 4 3 1 ADAM cysteine-rich Disintegrin PF00200.18 EMC86887.1 - 1e-19 70.5 26.7 1e-19 70.5 18.5 3.8 3 1 1 4 4 4 1 Disintegrin Reprolysin_5 PF13688.1 EMC86887.1 - 1.4e-18 67.5 0.1 3.6e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC86887.1 - 4.7e-17 62.6 0.0 8.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC86887.1 - 8.8e-17 61.6 0.2 1.9e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC86887.1 - 5.2e-14 52.2 0.2 1.5e-13 50.7 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC86887.1 - 0.0043 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EMC86887.1 - 0.023 13.5 0.1 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.8 EMC86887.1 - 0.035 13.6 0.2 0.071 12.7 0.2 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.6 EMC86887.1 - 0.11 12.3 0.6 0.25 11.1 0.4 1.5 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin PF01421.14 EMC86888.1 - 1.3e-47 161.9 1.6 3.2e-47 160.7 0.0 2.1 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC86888.1 - 3.2e-34 117.4 3.3 3.2e-34 117.4 2.3 4.1 5 1 0 5 5 5 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 EMC86888.1 - 6.9e-30 103.5 0.1 1.1e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 EMC86888.1 - 2e-19 69.5 28.8 2e-19 69.5 20.0 4.5 3 1 1 4 4 4 1 Disintegrin EGF_2 PF07974.8 EMC86888.1 - 0.00033 20.7 13.1 0.00033 20.7 9.1 7.1 6 1 1 7 7 7 1 EGF-like domain Reprolysin_3 PF13582.1 EMC86888.1 - 0.055 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC86888.1 - 0.056 13.4 0.1 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Pkinase PF00069.20 EMC86889.1 - 6.6e-62 208.9 0.1 1.4e-61 207.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86889.1 - 1.4e-22 79.9 0.1 1.4e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC86889.1 - 8.1e-06 25.0 0.1 2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC86889.1 - 0.00022 20.3 0.1 0.00041 19.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NTP_transf_4 PF13562.1 EMC86889.1 - 0.042 13.5 0.3 0.52 9.9 0.2 2.3 1 1 0 1 1 1 0 Sugar nucleotidyl transferase Choline_kinase PF01633.15 EMC86889.1 - 0.044 13.3 0.1 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EMC86889.1 - 0.099 12.3 0.3 0.4 10.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family APH PF01636.18 EMC86890.1 - 6.2e-37 127.6 0.0 1.1e-36 126.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.1 EMC86890.1 - 1.9e-12 47.7 0.0 1.5e-11 44.8 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase EcKinase PF02958.15 EMC86890.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Hydrolase PF00702.21 EMC86890.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RIO1 PF01163.17 EMC86890.1 - 0.052 12.8 0.0 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EMC86890.1 - 0.061 12.3 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acid_PPase PF12689.2 EMC86890.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Hydrolase_like PF13242.1 EMC86890.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like BRAP2 PF07576.7 EMC86891.1 - 4.3e-41 138.9 1.1 8.4e-41 137.9 0.7 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EMC86891.1 - 3.7e-20 71.8 8.8 3.7e-20 71.8 6.1 2.2 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EMC86891.1 - 1.2e-09 37.8 7.0 1.2e-09 37.8 4.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EMC86891.1 - 1.4e-06 27.9 5.6 1.4e-06 27.9 3.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain RRM_6 PF14259.1 EMC86891.1 - 4.8e-05 23.2 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EMC86891.1 - 6.2e-05 22.5 6.2 6.2e-05 22.5 4.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC86891.1 - 7.8e-05 22.7 5.7 7.8e-05 22.7 4.0 2.6 2 1 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMC86891.1 - 8.5e-05 22.5 5.6 8.5e-05 22.5 3.9 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC86891.1 - 0.00016 21.2 17.7 0.00043 19.8 5.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EMC86891.1 - 0.00064 19.2 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Apc11 PF12861.2 EMC86891.1 - 0.0042 16.8 3.1 0.017 14.9 2.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_PEP_C PF04513.7 EMC86891.1 - 0.091 12.5 8.1 0.1 12.4 4.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 EMC86891.1 - 0.21 11.0 3.6 0.58 9.6 0.7 2.7 1 1 1 2 2 2 0 Chordopoxvirus fusion protein Sec34 PF04136.10 EMC86891.1 - 0.31 10.7 13.6 0.62 9.7 9.4 1.4 1 0 0 1 1 1 0 Sec34-like family Adenylsucc_synt PF00709.16 EMC86891.1 - 0.32 9.6 5.4 0.48 9.0 3.7 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase DUF342 PF03961.8 EMC86891.1 - 0.4 9.0 15.0 0.61 8.4 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2317 PF10079.4 EMC86891.1 - 0.45 9.0 13.6 0.69 8.4 9.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) GBP_C PF02841.9 EMC86891.1 - 0.77 8.8 23.3 0.17 11.0 13.2 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain NPV_P10 PF05531.7 EMC86891.1 - 0.94 9.7 8.1 7 6.9 4.0 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-RING_6 PF14835.1 EMC86891.1 - 4.4 7.1 11.1 0.24 11.2 3.3 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-ribbon_3 PF13248.1 EMC86891.1 - 5.7 6.2 8.8 5 6.4 4.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Phe_ZIP PF08916.6 EMC86893.1 - 7.6e-22 77.4 5.8 1.5e-21 76.4 4.0 1.5 1 0 0 1 1 1 1 Phenylalanine zipper SH2 PF00017.19 EMC86893.1 - 1.2e-09 37.8 0.0 2.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH PF00169.24 EMC86893.1 - 3.1e-08 33.7 0.0 4.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EMC86893.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.24 EMC86894.1 - 4.3e-19 68.6 0.0 6.5e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC86894.1 - 2.9e-08 33.9 0.2 6.7e-06 26.3 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMC86894.1 - 1.9e-06 27.8 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 EMC86894.1 - 0.0011 19.0 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 EMC86894.1 - 0.014 15.2 0.9 0.13 12.1 0.6 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.1 EMC86894.1 - 0.017 14.6 0.1 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain EF-hand_1 PF00036.27 EMC86895.1 - 9.6e-13 46.4 3.3 5.1e-06 25.4 0.6 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EMC86895.1 - 5.9e-11 41.8 2.5 0.00058 19.4 0.0 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 EMC86895.1 - 1.1e-10 41.5 0.7 1.4e-06 28.3 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC86895.1 - 5.8e-09 35.1 1.2 2.9e-06 26.7 0.5 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EMC86895.1 - 4.6e-05 22.5 3.0 0.00032 19.8 1.1 2.9 3 0 0 3 3 3 1 EF hand mTERF PF02536.9 EMC86895.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 mTERF EF-hand_1 PF00036.27 EMC86896.1 - 9.6e-13 46.4 3.3 5.1e-06 25.4 0.6 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EMC86896.1 - 5.9e-11 41.8 2.5 0.00058 19.4 0.0 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 EMC86896.1 - 1.1e-10 41.5 0.7 1.4e-06 28.3 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC86896.1 - 5.8e-09 35.1 1.2 2.9e-06 26.7 0.5 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EMC86896.1 - 4.6e-05 22.5 3.0 0.00032 19.8 1.1 2.9 3 0 0 3 3 3 1 EF hand mTERF PF02536.9 EMC86896.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 mTERF Metallophos PF00149.23 EMC86898.1 - 1.9e-44 151.4 0.4 2.2e-44 151.2 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ion_trans PF00520.26 EMC86899.1 - 9.3e-05 21.7 7.7 9.3e-05 21.7 5.4 1.5 2 0 0 2 2 2 1 Ion transport protein IncA PF04156.9 EMC86899.1 - 0.0049 16.4 2.7 0.0088 15.6 1.9 1.4 1 0 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 EMC86899.1 - 0.037 13.8 7.4 0.056 13.2 5.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ERp29 PF07749.7 EMC86899.1 - 0.077 13.6 0.6 0.12 12.9 0.4 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain CcdA PF07362.7 EMC86899.1 - 7.4 6.5 6.7 0.24 11.3 0.5 1.5 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF1619 PF07773.6 EMC86900.1 - 1.3e-67 228.6 3.8 1.3e-67 228.6 2.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) SpoIIE PF07228.7 EMC86901.1 - 3.6e-15 56.1 0.0 5.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EMC86901.1 - 7.2e-07 28.8 0.1 2e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EMC86901.1 - 1.7e-05 24.3 0.1 0.0067 15.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Metallophos_2 PF12850.2 EMC86902.1 - 4.8e-21 75.2 0.1 5.7e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EMC86902.1 - 2.6e-07 30.2 2.3 0.00087 18.7 0.2 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Rod_C PF10493.4 EMC86903.1 - 9.5e-227 753.6 3.0 9.5e-227 753.6 2.1 1.8 2 0 0 2 2 2 1 Rough deal protein C-terminal region Turandot PF07240.6 EMC86903.1 - 0.098 12.1 0.1 0.4 10.1 0.1 2.1 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot PSP PF04046.11 EMC86904.1 - 5.3e-18 64.1 0.2 1.2e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.18 EMC86904.1 - 3e-06 26.8 3.9 5.3e-06 26.1 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EMC86904.1 - 0.0044 16.6 0.5 0.0099 15.5 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle CAP_GLY PF01302.20 EMC86905.1 - 1.5e-46 155.9 3.1 4.1e-24 84.0 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain HTH_11 PF08279.7 EMC86905.1 - 0.0083 15.7 0.2 0.18 11.4 0.0 3.3 2 0 0 2 2 2 1 HTH domain Sec1 PF00995.18 EMC86906.1 - 5.5e-125 418.1 0.0 6.3e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Galactosyl_T PF01762.16 EMC86907.1 - 7.6e-45 152.9 0.0 8.9e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC86907.1 - 2.4e-09 36.7 0.0 3.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Fringe-like LRR_4 PF12799.2 EMC86908.1 - 1.2e-14 53.5 14.9 2.8e-05 23.6 6.7 3.8 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC86908.1 - 8.6e-10 38.2 6.5 0.00091 18.9 2.0 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EMC86908.1 - 5.9e-06 25.6 12.5 0.49 10.6 1.7 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 EMC86908.1 - 9.7e-06 25.2 0.5 0.0025 17.4 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EMC86908.1 - 2.4e-05 23.9 13.0 0.044 13.8 1.6 5.2 3 2 2 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EMC86908.1 - 0.029 14.5 12.2 1.2 9.6 0.7 5.5 5 0 0 5 5 5 0 Leucine rich repeat HLH PF00010.21 EMC86909.1 - 3.9e-06 26.4 0.2 3.9e-06 26.4 0.1 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain FliJ PF02050.11 EMC86909.1 - 0.0045 17.0 1.1 0.011 15.7 0.7 1.6 1 0 0 1 1 1 1 Flagellar FliJ protein Troponin PF00992.15 EMC86909.1 - 0.016 15.2 0.1 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 Troponin DivIC PF04977.10 EMC86909.1 - 0.019 14.4 2.7 0.037 13.5 1.9 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 EMC86909.1 - 0.019 15.2 2.5 0.046 14.0 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4618 PF15397.1 EMC86909.1 - 0.057 12.7 2.4 0.11 11.8 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.16 EMC86909.1 - 0.34 10.9 3.4 0.96 9.4 2.2 1.8 1 1 1 2 2 2 0 bZIP transcription factor BCL_N PF04714.8 EMC86910.1 - 1.1e-08 34.5 1.7 1.5e-08 34.0 0.6 1.7 2 0 0 2 2 2 1 BCL7, N-terminal conserver region Defensin_propep PF00879.13 EMC86910.1 - 0.012 15.5 1.4 0.031 14.2 1.0 1.7 1 0 0 1 1 1 0 Defensin propeptide DUF1675 PF07897.6 EMC86910.1 - 2.6 7.8 16.5 3.3 7.5 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PDZ_2 PF13180.1 EMC86911.1 - 9.3e-10 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EMC86911.1 - 3.4e-07 30.3 0.1 5.1e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 EMC86911.1 - 5.1e-05 23.2 0.0 8e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain Glyoxalase PF00903.20 EMC86912.1 - 6.7e-22 77.8 0.6 2.2e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMC86912.1 - 5e-13 49.0 0.1 5.7e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMC86912.1 - 1.1e-07 32.3 0.1 8.4e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EMC86912.1 - 0.00068 19.5 0.1 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EMC86912.1 - 0.0013 18.6 0.0 1.5 8.7 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Rubella_E2 PF05749.6 EMC86913.1 - 0.0021 17.3 0.2 0.0021 17.3 0.1 1.4 2 0 0 2 2 2 1 Rubella membrane glycoprotein E2 Ras PF00071.17 EMC86915.1 - 1.2e-28 99.5 0.0 1.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC86915.1 - 3.1e-06 27.6 0.0 6.5e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein GTSE1_N PF15259.1 EMC86915.1 - 0.14 12.0 0.6 0.18 11.7 0.4 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 TMPIT PF07851.8 EMC86916.1 - 2.7e-158 526.3 16.9 3.3e-158 526.0 11.7 1.0 1 0 0 1 1 1 1 TMPIT-like protein MORN PF02493.15 EMC86917.1 - 4.6e-25 85.8 44.2 3.8e-05 23.1 1.9 6.9 7 0 0 7 7 7 6 MORN repeat Orai-1 PF07856.7 EMC86918.1 - 4.6e-59 198.9 3.2 5.3e-59 198.7 2.2 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity 7tm_3 PF00003.17 EMC86918.1 - 0.013 14.8 1.5 0.017 14.4 1.1 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR KASH PF10541.4 EMC86918.1 - 0.024 14.4 0.5 0.71 9.7 0.1 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain 7TM_GPCR_Str PF10326.4 EMC86918.1 - 0.026 13.6 3.8 1.5 7.8 0.2 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str MscS_TM PF12794.2 EMC86918.1 - 0.032 12.8 0.4 0.032 12.8 0.3 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF2207 PF09972.4 EMC86918.1 - 0.052 12.1 0.0 0.071 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) m04gp34like PF12216.3 EMC86918.1 - 0.071 12.4 0.2 0.76 9.0 0.0 2.0 1 1 1 2 2 2 0 Immune evasion protein DUF3357 PF11837.3 EMC86918.1 - 0.081 12.7 3.9 1.9 8.3 0.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) DUF4328 PF14219.1 EMC86918.1 - 0.095 11.9 0.8 2.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) DctQ PF04290.7 EMC86918.1 - 0.099 12.4 0.2 0.099 12.4 0.2 1.8 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1282 PF06930.7 EMC86918.1 - 0.11 12.1 2.6 0.085 12.5 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) Neurensin PF14927.1 EMC86918.1 - 0.22 10.8 2.2 1.7 8.0 0.7 2.3 1 1 1 2 2 2 0 Neurensin zf-CXXC PF02008.15 EMC86919.1 - 1.3e-14 53.7 21.5 1.3e-14 53.7 14.9 3.0 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.28 EMC86919.1 - 2.9e-13 49.0 6.9 1.5e-12 46.8 1.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC86919.1 - 4.7e-09 35.8 6.1 1.3e-08 34.4 4.2 1.8 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.1 EMC86919.1 - 1.3e-06 28.1 2.2 2.9e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 Cupin-like domain LRR_8 PF13855.1 EMC86919.1 - 1.6e-05 24.5 7.4 0.28 10.9 0.2 4.4 4 0 0 4 4 4 3 Leucine rich repeat JmjC PF02373.17 EMC86919.1 - 6e-05 23.2 0.3 6e-05 23.2 0.2 3.2 3 1 0 3 3 3 1 JmjC domain, hydroxylase LRR_6 PF13516.1 EMC86919.1 - 0.00042 20.0 14.5 1 9.6 0.0 6.9 8 0 0 8 8 8 2 Leucine Rich repeat DUF4109 PF13397.1 EMC86919.1 - 0.0061 16.9 0.6 0.026 14.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4109) LRR_1 PF00560.28 EMC86919.1 - 8.8 6.8 12.6 30 5.1 0.1 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat 7tm_1 PF00001.16 EMC86920.1 - 1.4e-34 119.4 26.6 1.9e-34 118.9 18.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC86920.1 - 4.2e-10 39.2 25.9 5.4e-10 38.8 17.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Rax2 PF12768.2 EMC86920.1 - 0.097 11.8 1.1 2 7.5 0.1 2.2 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Pkinase PF00069.20 EMC86921.1 - 3.2e-66 223.1 0.0 4.8e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC86921.1 - 5.3e-34 117.4 0.0 1e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC86921.1 - 2.8e-09 36.3 0.0 4.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC86921.1 - 0.011 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EMC86921.1 - 0.036 13.8 0.2 0.81 9.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMC86921.1 - 0.19 10.5 0.4 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 DUF948 PF06103.6 EMC86922.1 - 0.4 10.5 16.9 1.7 8.5 0.4 5.0 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EMC86922.1 - 4.7 6.2 8.4 1.8 7.6 0.2 3.0 2 1 0 3 3 3 0 Reovirus sigma C capsid protein NPBW PF15180.1 EMC86922.1 - 7.6 6.2 7.5 0.46 10.1 0.1 2.8 3 1 0 3 3 3 0 Neuropeptides B and W NPV_P10 PF05531.7 EMC86922.1 - 7.6 6.8 15.3 36 4.6 0.4 5.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein SH3_2 PF07653.12 EMC86923.1 - 0.074 12.5 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain E1-E2_ATPase PF00122.15 EMC86924.1 - 9.6e-60 201.4 2.7 1.3e-57 194.4 1.2 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC86924.1 - 5.5e-45 153.1 2.4 5.5e-45 153.1 1.7 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC86924.1 - 4.1e-29 102.5 0.1 8.3e-23 81.9 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC86924.1 - 1e-22 79.8 0.4 2.5e-22 78.6 0.3 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMC86924.1 - 5.7e-18 64.1 1.2 4.2e-17 61.3 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC86924.1 - 1.6e-14 54.5 0.4 6.2e-14 52.5 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC86924.1 - 2.3e-05 24.1 0.6 2.3e-05 24.1 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 EMC86925.1 - 7.8e-21 73.5 12.8 0.00058 19.4 0.3 6.8 5 2 1 6 6 6 5 TPR repeat TPR_16 PF13432.1 EMC86925.1 - 2.2e-17 63.1 0.7 0.00047 20.7 0.1 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC86925.1 - 4.7e-17 60.4 18.2 0.00042 20.0 0.0 9.5 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86925.1 - 7.2e-17 61.4 5.7 7.2e-05 23.0 0.0 5.9 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC86925.1 - 3e-16 58.4 9.1 0.054 14.1 0.0 8.8 5 4 5 10 10 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC86925.1 - 2.5e-12 45.8 12.6 0.0035 16.8 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMC86925.1 - 3.6e-09 35.7 3.2 0.12 12.1 0.0 5.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86925.1 - 3.9e-09 36.3 15.0 2.8 7.9 0.0 7.9 4 2 2 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EMC86925.1 - 5.2e-07 29.7 17.0 0.19 11.8 0.3 5.9 5 2 2 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMC86925.1 - 9.2e-07 28.2 7.1 0.45 10.4 0.0 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC86925.1 - 6.5e-05 23.1 11.1 1.6 9.3 0.0 6.9 9 0 0 9 9 7 2 Tetratricopeptide repeat ChAPs PF09295.5 EMC86925.1 - 0.0002 20.2 2.5 0.22 10.2 0.1 3.3 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 EMC86925.1 - 0.00024 21.0 8.2 0.00035 20.5 0.9 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86925.1 - 0.033 14.3 10.7 40 4.7 0.1 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.2 EMC86925.1 - 0.046 13.7 1.3 4 7.4 0.0 3.8 3 1 2 5 5 5 0 Tetratrico peptide repeat TPR_20 PF14561.1 EMC86925.1 - 0.051 13.6 5.5 8.9 6.5 0.2 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat P21-Arc PF04062.9 EMC86926.1 - 4.4e-80 267.5 0.1 4.9e-80 267.4 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit SUI1 PF01253.17 EMC86927.1 - 3.4e-17 62.0 0.3 6e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TMF_DNA_bd PF12329.3 EMC86928.1 - 0.015 15.0 5.2 0.015 15.0 3.6 4.8 2 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding BRX_N PF13713.1 EMC86928.1 - 0.016 14.6 0.9 0.66 9.4 0.1 3.2 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain Golgin_A5 PF09787.4 EMC86928.1 - 0.21 10.0 38.7 0.049 12.1 11.0 2.4 1 1 0 2 2 2 0 Golgin subfamily A member 5 Reo_sigmaC PF04582.7 EMC86928.1 - 2.8 7.0 8.0 6.6 5.8 0.3 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein ANTH PF07651.11 EMC86930.1 - 2.9e-71 239.4 0.1 2.9e-71 239.4 0.0 2.6 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 EMC86930.1 - 3.3e-26 92.0 1.6 3.3e-26 92.0 1.1 5.6 3 1 1 6 6 6 1 I/LWEQ domain ENTH PF01417.15 EMC86930.1 - 3.8e-07 30.0 0.0 1.2e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 ENTH domain DUF3584 PF12128.3 EMC86930.1 - 1.9 5.6 60.1 0.083 10.2 35.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Mod_r PF07200.8 EMC86931.1 - 2.5e-40 137.8 9.7 3.1e-40 137.5 6.7 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Muted PF14942.1 EMC86931.1 - 0.096 12.5 1.2 0.39 10.5 0.0 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ABC_membrane PF00664.18 EMC86932.1 - 1.9e-53 181.6 17.9 3.8e-53 180.6 12.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMC86932.1 - 9.8e-34 116.5 0.0 2.2e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMC86932.1 - 1.3e-10 40.9 0.8 2.2e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMC86932.1 - 4e-05 22.8 0.1 0.00011 21.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_membrane_3 PF13748.1 EMC86932.1 - 4.1e-05 22.7 4.0 8.7e-05 21.6 2.8 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 EMC86932.1 - 0.00019 21.5 0.2 0.00045 20.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EMC86932.1 - 0.00022 21.3 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC86932.1 - 0.001 19.2 0.0 0.0043 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMC86932.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4191 PF13829.1 EMC86932.1 - 0.016 14.3 0.0 0.061 12.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SbcCD_C PF13558.1 EMC86932.1 - 0.03 14.2 0.4 0.22 11.4 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EMC86932.1 - 0.078 12.3 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMC86932.1 - 0.17 12.1 0.0 0.57 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain zf-H2C2 PF09337.5 EMC86933.1 - 2.8e-05 23.4 1.2 5.1e-05 22.5 0.8 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 EMC86933.1 - 0.0047 17.0 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF2348 PF09807.4 EMC86933.1 - 0.015 14.3 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) 2OG-FeII_Oxy PF03171.15 EMC86934.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.4 EMC86935.1 - 4.3e-72 242.2 76.9 1.9e-71 240.1 20.1 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein DUF936 PF06075.7 EMC86935.1 - 1.7 7.4 36.8 1.9 7.2 25.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) IP_trans PF02121.13 EMC86936.1 - 6e-97 323.7 0.6 6.6e-97 323.6 0.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Cast PF10174.4 EMC86937.1 - 0.0002 19.5 35.0 0.00059 18.0 24.2 1.8 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Myosin_tail_1 PF01576.14 EMC86937.1 - 0.00029 18.7 31.3 0.00029 18.7 21.7 2.3 2 1 0 2 2 2 1 Myosin tail AAA_13 PF13166.1 EMC86937.1 - 0.00035 19.1 25.8 0.00082 17.9 17.9 1.5 1 0 0 1 1 1 1 AAA domain Tropomyosin PF00261.15 EMC86937.1 - 0.0014 17.8 29.6 0.12 11.4 12.5 3.1 1 1 1 2 2 2 2 Tropomyosin Tup_N PF08581.5 EMC86937.1 - 0.0076 16.4 18.8 0.045 13.9 0.2 4.2 2 1 1 3 3 3 2 Tup N-terminal ATG16 PF08614.6 EMC86937.1 - 0.011 15.5 8.9 0.011 15.5 6.2 4.3 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EMC86937.1 - 0.014 15.3 41.9 0.16 11.8 5.5 4.4 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EMC86937.1 - 0.017 14.3 9.9 0.063 12.4 2.5 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EMC86937.1 - 0.022 14.9 21.8 0.71 10.0 5.3 3.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 EMC86937.1 - 0.071 11.2 23.4 0.15 10.2 16.2 1.5 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF745 PF05335.8 EMC86937.1 - 0.082 12.4 12.4 0.13 11.7 8.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Lebercilin PF15619.1 EMC86937.1 - 0.2 11.0 39.2 0.072 12.5 8.7 3.0 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease RPW8 PF05659.6 EMC86937.1 - 0.21 11.1 7.2 0.51 9.8 3.4 2.6 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.7 EMC86937.1 - 0.24 11.1 20.8 0.08 12.7 2.7 3.3 2 1 1 3 3 2 0 Laminin Domain II CCDC155 PF14662.1 EMC86937.1 - 0.25 10.9 27.1 0.93 9.0 6.1 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 IncA PF04156.9 EMC86937.1 - 0.26 10.8 33.1 0.052 13.1 10.7 3.8 2 1 1 3 3 3 0 IncA protein Fib_alpha PF08702.5 EMC86937.1 - 0.28 11.3 24.2 0.23 11.6 1.9 4.3 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 EMC86937.1 - 0.6 9.8 26.1 0.15 11.8 0.6 5.5 2 1 2 4 4 4 0 Prefoldin subunit GAS PF13851.1 EMC86937.1 - 1.1 8.3 41.0 0.045 12.9 9.0 3.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding CENP-F_N PF10481.4 EMC86937.1 - 1.4 8.2 33.5 0.089 12.1 9.2 3.6 2 1 2 4 4 4 0 Cenp-F N-terminal domain Med9 PF07544.8 EMC86937.1 - 2 8.2 14.2 1.5 8.6 0.4 4.5 2 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 EMC86937.1 - 2.3 7.9 36.4 2.9 7.6 5.6 4.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.4 EMC86937.1 - 2.7 6.6 31.7 0.12 11.0 10.9 2.6 2 1 1 3 3 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.7 EMC86937.1 - 3.1 7.5 13.8 0.32 10.8 1.1 3.1 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 EMC86937.1 - 3.1 8.2 16.4 5.6 7.4 1.5 4.6 1 1 2 4 4 4 0 SlyX WXG100 PF06013.7 EMC86937.1 - 4 7.4 10.9 3.8 7.5 0.7 3.8 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Fzo_mitofusin PF04799.8 EMC86937.1 - 8 5.8 24.8 0.62 9.4 1.1 4.2 2 1 2 4 4 4 0 fzo-like conserved region Tropomyosin_1 PF12718.2 EMC86937.1 - 8.8 6.1 46.3 0.052 13.3 14.2 3.6 3 1 1 4 4 2 0 Tropomyosin like DMPK_coil PF08826.5 EMC86937.1 - 9.2 6.2 22.4 1.7 8.5 1.2 5.1 2 1 2 4 4 4 0 DMPK coiled coil domain like RF-1 PF00472.15 EMC86938.1 - 3.1e-24 84.9 4.7 4.1e-24 84.5 3.3 1.1 1 0 0 1 1 1 1 RF-1 domain DUF620 PF04788.7 EMC86938.1 - 0.04 13.0 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF620) DUF4337 PF14235.1 EMC86938.1 - 9.9 5.9 7.6 14 5.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CDK2AP PF09806.4 EMC86939.1 - 3.7e-36 125.1 0.0 4.2e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AAA_34 PF13872.1 EMC86940.1 - 5e-137 455.6 0.0 7.2e-137 455.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.1 EMC86940.1 - 9e-117 389.4 0.0 1.5e-116 388.6 0.0 1.4 1 0 0 1 1 1 1 Helicase_C-like ResIII PF04851.10 EMC86940.1 - 1.7e-06 27.9 0.6 6.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMC86940.1 - 0.0024 17.6 0.1 0.0077 16.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SET PF00856.23 EMC86941.1 - 8.6e-20 71.6 1.3 8.8e-19 68.3 0.0 2.7 2 1 0 2 2 2 1 SET domain DUF3723 PF12520.3 EMC86942.1 - 0.038 12.4 0.2 0.038 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) RRM_1 PF00076.17 EMC86943.1 - 7.9e-18 63.8 0.1 1.2e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC86943.1 - 1.5e-11 44.0 0.0 2.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC86943.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RILP PF11461.3 EMC86944.1 - 1.9e-23 82.3 3.5 1.9e-23 82.3 2.4 2.6 2 1 0 2 2 2 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.4 EMC86944.1 - 2.9e-13 50.0 6.5 2.9e-13 50.0 4.5 3.5 2 1 1 4 4 4 1 JNK_SAPK-associated protein-1 YflT PF11181.3 EMC86944.1 - 0.0053 16.8 2.5 0.014 15.5 1.1 2.2 2 1 0 2 2 2 1 Heat induced stress protein YflT Spc42p PF11544.3 EMC86944.1 - 0.033 14.1 1.0 0.033 14.1 0.7 3.9 3 1 0 3 3 3 0 Spindle pole body component Spc42p UBA_e1_C PF09358.5 EMC86944.1 - 0.98 9.5 5.4 0.28 11.3 0.1 2.7 2 2 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain IncA PF04156.9 EMC86944.1 - 4.5 6.8 34.5 1.2 8.6 8.5 2.2 1 1 1 2 2 2 0 IncA protein DUF4407 PF14362.1 EMC86944.1 - 6.9 5.5 17.3 3.6 6.4 7.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DEAD PF00270.24 EMC86945.1 - 1.5e-41 141.7 0.0 1.7e-40 138.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMC86945.1 - 1.1e-20 72.9 0.6 2.9e-20 71.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMC86945.1 - 4.5e-20 71.3 0.1 3.2e-19 68.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4137 PF13593.1 EMC86945.1 - 0.0027 16.8 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.1 EMC86945.1 - 0.023 14.8 0.3 0.071 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IF-2B PF01008.12 EMC86946.1 - 8.6e-71 238.1 0.0 9.8e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Tfb4 PF03850.9 EMC86947.1 - 2.1e-97 325.7 0.8 2.5e-97 325.4 0.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Ku_N PF03731.10 EMC86947.1 - 0.045 13.1 0.1 0.29 10.5 0.1 1.9 1 1 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 EMC86947.1 - 0.045 13.8 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Baculo_IE-1 PF05290.6 EMC86947.1 - 1.8 8.3 8.1 0.56 9.9 3.3 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF1619 PF07773.6 EMC86948.1 - 3.3e-55 187.9 5.4 5.5e-55 187.2 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) L_protein_N PF15518.1 EMC86948.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus DHC_N1 PF08385.7 EMC86949.1 - 1.5e-101 340.6 15.1 5.1e-58 196.8 0.9 3.2 2 1 1 3 3 3 3 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 EMC86950.1 - 2.2e-206 687.1 0.0 5.6e-206 685.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EMC86950.1 - 7e-135 449.6 7.9 7e-135 449.6 5.5 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EMC86950.1 - 3.4e-104 347.3 0.1 3.2e-103 344.2 0.1 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EMC86950.1 - 1.4e-80 270.1 0.0 2.7e-80 269.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 EMC86950.1 - 1.8e-56 191.1 1.2 1.4e-55 188.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 EMC86950.1 - 8.8e-56 188.2 2.2 1.2e-55 187.8 0.5 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 EMC86950.1 - 2.1e-48 164.8 15.0 3.5e-48 164.1 10.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EMC86950.1 - 3.8e-26 91.4 0.6 7.9e-07 28.8 0.0 6.1 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMC86950.1 - 4.1e-11 43.1 0.1 0.18 11.9 0.0 5.6 4 0 0 4 4 4 3 AAA domain AAA PF00004.24 EMC86950.1 - 1.1e-07 32.0 5.9 0.61 10.2 0.0 5.8 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC86950.1 - 2.6e-07 31.4 0.1 0.2 12.4 0.0 4.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMC86950.1 - 8.1e-06 25.9 5.7 0.39 10.6 0.0 5.7 6 1 1 7 7 5 1 AAA ATPase domain DUF258 PF03193.11 EMC86950.1 - 4.6e-05 22.6 0.0 0.0052 15.9 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMC86950.1 - 5.5e-05 23.2 0.1 3.3 7.9 0.0 3.8 3 0 0 3 3 3 1 RNA helicase Sigma54_activat PF00158.21 EMC86950.1 - 0.0002 20.8 0.1 2.4 7.5 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.1 EMC86950.1 - 0.0015 18.8 2.9 2.9 8.1 0.0 5.5 6 0 0 6 6 4 1 AAA domain T2SE PF00437.15 EMC86950.1 - 0.0022 16.9 0.7 0.9 8.3 0.0 3.1 3 0 0 3 3 2 1 Type II/IV secretion system protein Cep57_CLD_2 PF14197.1 EMC86950.1 - 0.0028 17.5 4.9 0.0028 17.5 3.4 3.1 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 AAA_33 PF13671.1 EMC86950.1 - 0.0079 16.0 0.4 14 5.5 0.0 3.9 4 0 0 4 4 3 0 AAA domain DnaB_bind PF10410.4 EMC86950.1 - 0.0093 15.9 0.2 0.16 11.9 0.0 3.1 3 0 0 3 3 2 1 DnaB-helicase binding domain of primase AAA_29 PF13555.1 EMC86950.1 - 0.014 14.8 0.0 0.53 9.8 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EMC86950.1 - 0.014 14.7 0.9 13 5.1 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EMC86950.1 - 0.015 15.0 3.4 8.3 6.2 0.5 4.3 4 0 0 4 4 4 0 Part of AAA domain ABC_tran PF00005.22 EMC86950.1 - 0.036 14.3 0.2 1.7 8.9 0.1 3.6 3 0 0 3 3 3 0 ABC transporter Sigma54_activ_2 PF14532.1 EMC86950.1 - 0.037 14.0 4.1 3.2 7.7 0.0 5.1 5 0 0 5 5 5 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EMC86950.1 - 0.075 12.5 0.0 21 4.5 0.0 3.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 EMC86950.1 - 0.12 11.5 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EMC86950.1 - 0.14 11.5 4.1 0.58 9.5 0.0 3.6 4 0 0 4 4 3 0 AAA-like domain CCDC92 PF14916.1 EMC86951.1 - 3.8e-23 80.8 15.0 8.9e-23 79.6 2.2 2.8 2 1 1 3 3 3 2 Coiled-coil domain of unknown function Sigma54_DBD PF04552.8 EMC86951.1 - 0.0033 16.9 2.7 0.0033 16.9 1.9 1.8 2 0 0 2 2 2 1 Sigma-54, DNA binding domain Angiomotin_C PF12240.3 EMC86951.1 - 0.0034 16.9 7.2 0.0034 16.9 5.0 2.2 1 1 2 3 3 3 1 Angiomotin C terminal DUF812 PF05667.6 EMC86951.1 - 0.005 15.4 8.0 0.005 15.4 5.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF812) DUF4407 PF14362.1 EMC86951.1 - 0.0079 15.1 5.3 0.01 14.7 3.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.4 EMC86951.1 - 0.0083 15.9 25.8 0.093 12.5 0.7 2.5 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSBP1 PF06825.7 EMC86951.1 - 0.013 15.0 1.5 0.025 14.1 0.0 2.3 2 1 1 3 3 2 0 Heat shock factor binding protein 1 DUF4618 PF15397.1 EMC86951.1 - 0.017 14.4 1.2 0.017 14.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) CagA PF03507.8 EMC86951.1 - 0.023 14.5 1.2 0.047 13.5 0.7 1.7 1 1 1 2 2 2 0 CagA exotoxin Rootletin PF15035.1 EMC86951.1 - 0.036 14.0 16.5 0.13 12.2 11.4 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion XLF PF09302.6 EMC86951.1 - 0.05 13.3 1.1 0.05 13.3 0.8 2.7 2 1 0 2 2 2 0 XLF (XRCC4-like factor) IncA PF04156.9 EMC86951.1 - 0.052 13.1 22.4 0.38 10.3 0.9 2.9 2 1 1 3 3 3 0 IncA protein Med30 PF11315.3 EMC86951.1 - 0.058 13.5 8.7 0.015 15.4 3.5 1.8 1 1 1 2 2 2 0 Mediator complex subunit 30 FlxA PF14282.1 EMC86951.1 - 0.091 12.7 17.0 0.054 13.4 1.8 3.2 1 1 2 3 3 3 0 FlxA-like protein DUF2775 PF10950.3 EMC86951.1 - 0.14 12.4 3.2 2.6 8.2 2.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2775) V_ATPase_I PF01496.14 EMC86951.1 - 0.14 10.0 9.4 0.18 9.6 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phenol_Hydrox PF02332.13 EMC86951.1 - 0.14 11.4 1.8 0.18 11.0 0.3 1.7 2 0 0 2 2 2 0 Methane/Phenol/Toluene Hydroxylase HrpB7 PF09486.5 EMC86951.1 - 0.17 11.8 12.7 5.3 6.9 5.2 2.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Phage_GP20 PF06810.6 EMC86951.1 - 0.27 10.6 19.6 0.33 10.3 0.4 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 NYD-SP28 PF14772.1 EMC86951.1 - 0.34 11.0 14.3 0.46 10.6 5.3 2.6 2 1 0 2 2 2 0 Sperm tail DUF3584 PF12128.3 EMC86951.1 - 0.4 7.9 14.7 0.46 7.7 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.6 EMC86951.1 - 0.46 10.2 22.0 1.2 8.8 1.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 EMC86951.1 - 0.49 10.3 22.9 0.56 10.1 4.5 3.5 2 2 1 3 3 3 0 bZIP transcription factor APG6 PF04111.7 EMC86951.1 - 0.64 9.0 21.2 0.15 11.0 10.8 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1098 PF06497.6 EMC86951.1 - 0.65 10.0 6.0 0.21 11.6 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) CENP-Q PF13094.1 EMC86951.1 - 1.6 8.7 25.1 1.8 8.5 2.2 2.5 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 EMC86951.1 - 1.7 7.5 18.8 0.25 10.2 7.6 2.0 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SseC PF04888.7 EMC86951.1 - 1.8 7.7 9.2 0.52 9.6 2.2 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family TPR_MLP1_2 PF07926.7 EMC86951.1 - 3.1 7.5 23.6 0.46 10.2 8.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EMC86951.1 - 3.2 7.6 25.5 3.5 7.4 3.3 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 EMC86951.1 - 3.4 7.5 8.3 35 4.3 0.1 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 EMC86951.1 - 3.8 7.0 17.0 0.44 10.0 3.4 3.7 2 2 0 3 3 3 0 Septum formation initiator MSG PF02349.10 EMC86951.1 - 5.2 7.1 13.2 13 5.8 8.4 2.2 1 1 1 2 2 2 0 Major surface glycoprotein ADIP PF11559.3 EMC86951.1 - 7.1 6.5 24.3 15 5.4 2.6 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 EMC86951.1 - 7.5 6.3 16.6 16 5.2 6.7 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) FAM101 PF15068.1 EMC86952.1 - 7.1e-97 322.8 0.0 8.1e-97 322.6 0.0 1.0 1 0 0 1 1 1 1 FAM101 family ubiquitin PF00240.18 EMC86953.1 - 3.2e-106 346.7 11.8 8e-35 118.0 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EMC86953.1 - 8.4e-62 204.8 10.9 6.9e-20 70.5 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC86953.1 - 1.7e-21 76.2 3.6 2.4e-05 24.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMC86953.1 - 9.9e-16 57.8 0.1 0.0012 18.5 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMC86953.1 - 1.4e-11 44.2 0.9 0.049 13.5 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMC86953.1 - 5.4e-10 39.3 0.2 0.16 12.2 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EMC86953.1 - 4.9e-09 35.9 1.1 0.25 11.3 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF2870 PF11069.3 EMC86953.1 - 6.5e-08 32.5 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EMC86953.1 - 8e-06 25.5 0.6 3.7 7.3 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain USP7_C2 PF14533.1 EMC86953.1 - 8.3e-05 22.1 1.6 4.2 6.7 0.0 3.1 1 1 0 3 3 3 3 Ubiquitin-specific protease C-terminal CTDII PF01556.13 EMC86953.1 - 0.0022 17.8 8.8 1.8 8.5 0.2 3.3 1 1 1 3 3 3 2 DnaJ C terminal domain Plexin_cytopl PF08337.7 EMC86953.1 - 0.0025 16.2 5.1 3.8 5.7 0.1 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain FERM_N PF09379.5 EMC86953.1 - 0.0033 17.4 3.6 27 4.9 0.1 4.7 3 3 0 3 3 3 0 FERM N-terminal domain GABP-alpha PF11620.3 EMC86953.1 - 0.014 15.3 1.0 38 4.3 0.0 3.0 3 0 0 3 3 3 0 GA-binding protein alpha chain YfmQ PF10787.4 EMC86953.1 - 0.015 14.6 0.2 33 3.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein from bacillus cereus group EMG1 PF03587.9 EMC86953.1 - 0.02 14.1 0.1 13 5.0 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase DUF3781 PF12636.2 EMC86953.1 - 0.33 10.9 1.9 1.1e+02 2.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) YajC PF02699.10 EMC86953.1 - 0.62 9.7 4.1 37 4.0 0.0 3.1 3 0 0 3 3 3 0 Preprotein translocase subunit Sec_GG PF07549.9 EMC86953.1 - 1.9 7.8 5.5 1.8e+02 1.6 0.0 4.6 5 0 0 5 5 5 0 SecD/SecF GG Motif OB_NTP_bind PF07717.11 EMC86954.1 - 1.8e-25 88.9 0.0 3.8e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC86954.1 - 1.2e-17 63.7 0.0 1.2e-17 63.7 0.0 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) DEAD PF00270.24 EMC86954.1 - 3.3e-12 46.2 0.1 3.3e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC86954.1 - 1.2e-08 34.6 0.0 4.5e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMC86954.1 - 3e-07 30.6 0.1 2.5e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EMC86954.1 - 0.0022 16.9 0.0 0.0084 15.0 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EMC86954.1 - 0.003 17.3 1.0 0.037 13.7 0.0 2.8 3 0 0 3 3 3 1 Flavivirus DEAD domain KaiC PF06745.8 EMC86954.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 EMC86954.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMC86954.1 - 0.024 14.3 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 EMC86954.1 - 0.028 14.1 0.2 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EMC86954.1 - 0.04 14.2 10.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EMC86954.1 - 0.09 12.6 6.5 0.15 11.9 0.1 3.4 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit G-alpha PF00503.15 EMC86954.1 - 3.4 6.2 6.2 0.17 10.5 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit BRI3BP PF14965.1 EMC86955.1 - 3.5e-80 267.5 0.5 3.9e-80 267.3 0.3 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 AMP-binding PF00501.23 EMC86956.1 - 3.6e-46 157.3 0.0 5.2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PTR2 PF00854.16 EMC86960.1 - 1.2e-83 280.9 8.7 1.7e-83 280.4 6.0 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 EMC86960.1 - 8.2e-10 37.9 11.5 8.2e-10 37.9 7.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Glycos_transf_1 PF00534.15 EMC86961.1 - 2.1e-21 76.0 0.0 3.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC86961.1 - 8.1e-12 45.4 0.0 1.6e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMC86961.1 - 1.9e-09 37.6 0.0 3.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Frizzled PF01534.12 EMC86964.1 - 3.9e-143 476.1 22.0 4.9e-143 475.8 15.3 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 EMC86964.1 - 7.7e-34 116.5 6.4 1.8e-33 115.3 4.5 1.7 1 0 0 1 1 1 1 Fz domain Piwi PF02171.12 EMC86965.1 - 1.6e-108 362.2 0.0 2.7e-108 361.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EMC86965.1 - 1.9e-39 134.0 0.5 3.2e-39 133.3 0.3 1.4 1 0 0 1 1 1 1 PAZ domain SH3_2 PF07653.12 EMC86966.1 - 4.3e-33 112.5 0.0 1.4e-10 40.4 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.1 EMC86966.1 - 1.5e-30 104.5 1.7 8.4e-13 47.6 0.1 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 EMC86966.1 - 2.4e-16 58.8 0.1 1.1e-06 27.9 0.0 3.9 3 1 0 3 3 3 3 SH3 domain fn3 PF00041.16 EMC86966.1 - 3e-13 49.7 4.9 0.00011 22.2 0.1 4.1 3 1 0 3 3 3 3 Fibronectin type III domain ADIP PF11559.3 EMC86966.1 - 1.3 8.9 12.6 2.5 8.0 8.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1423 PF07227.6 EMC86966.1 - 1.4 7.4 6.9 2.2 6.8 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Syntaxin PF00804.20 EMC86967.1 - 3.3e-36 123.5 6.3 3.3e-36 123.5 4.3 2.5 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 EMC86967.1 - 5.1e-23 80.5 3.3 5.1e-23 80.5 2.3 3.2 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 EMC86967.1 - 2.8e-05 24.0 16.4 3.3e-05 23.8 5.4 2.9 1 1 1 2 2 2 1 Syntaxin-like protein UBN2 PF14223.1 EMC86967.1 - 0.0062 16.3 0.8 0.0062 16.3 0.6 2.9 2 1 1 3 3 3 1 gag-polypeptide of LTR copia-type MCPsignal PF00015.16 EMC86967.1 - 0.0085 15.6 11.4 0.18 11.3 0.8 2.4 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain COG5 PF10392.4 EMC86967.1 - 0.0097 15.8 9.3 0.36 10.7 0.8 2.7 2 2 0 2 2 2 2 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EMC86967.1 - 0.01 15.6 2.4 0.42 10.4 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med28 PF11594.3 EMC86967.1 - 0.018 15.2 6.4 1.1 9.4 0.4 2.5 1 1 0 2 2 2 0 Mediator complex subunit 28 Takusan PF04822.8 EMC86967.1 - 0.042 13.6 0.7 0.042 13.6 0.5 3.3 3 1 0 3 3 3 0 Takusan SUR7 PF06687.7 EMC86967.1 - 0.052 13.0 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF3899 PF13038.1 EMC86967.1 - 0.057 13.5 2.9 0.13 12.4 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) AAA_13 PF13166.1 EMC86967.1 - 0.059 11.8 19.8 0.041 12.3 9.3 2.0 1 1 1 2 2 2 0 AAA domain DUF1845 PF08900.6 EMC86967.1 - 0.063 12.5 2.5 0.09 12.0 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1845) PBP1_TM PF14812.1 EMC86967.1 - 0.075 13.3 1.2 0.19 12.0 0.1 2.3 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KIP1 PF07765.7 EMC86967.1 - 0.079 12.8 5.5 1.8 8.4 0.3 3.0 3 1 0 3 3 2 0 KIP1-like protein DUF3753 PF12575.3 EMC86967.1 - 0.11 12.3 0.4 0.31 10.8 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF677 PF05055.7 EMC86967.1 - 0.11 11.1 14.1 0.076 11.6 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF677) NPV_P10 PF05531.7 EMC86967.1 - 0.13 12.5 4.3 12 6.2 0.0 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Flu_NS2 PF00601.14 EMC86967.1 - 0.13 12.4 7.2 0.055 13.6 0.8 2.9 2 2 1 3 3 3 0 Influenza non-structural protein (NS2) Serine_rich PF08824.5 EMC86967.1 - 0.13 11.9 4.4 0.31 10.7 0.7 2.4 1 1 1 2 2 2 0 Serine rich protein interaction domain CENP-Q PF13094.1 EMC86967.1 - 0.14 12.2 16.4 1.2 9.1 0.3 3.2 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Mur_ligase_M PF08245.7 EMC86967.1 - 0.14 12.1 6.4 0.088 12.8 0.7 2.6 2 1 0 2 2 2 0 Mur ligase middle domain DUF912 PF06024.7 EMC86967.1 - 0.15 12.1 1.1 0.53 10.3 0.7 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3671 PF12420.3 EMC86967.1 - 0.16 11.9 1.2 0.29 11.1 0.1 2.0 2 0 0 2 2 1 0 Protein of unknown function FH2 PF02181.18 EMC86967.1 - 0.2 10.5 15.7 0.17 10.7 1.3 2.6 1 1 1 3 3 3 0 Formin Homology 2 Domain T2SF PF00482.18 EMC86967.1 - 0.21 11.5 6.2 0.3 11.0 0.7 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF713 PF05218.9 EMC86967.1 - 0.22 11.2 12.3 0.09 12.5 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) DUF342 PF03961.8 EMC86967.1 - 0.23 9.8 17.8 0.0055 15.1 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SF3b1 PF08920.5 EMC86967.1 - 0.26 11.2 2.8 0.3 11.1 0.8 2.1 1 1 1 2 2 1 0 Splicing factor 3B subunit 1 DUF2116 PF09889.4 EMC86967.1 - 0.3 10.9 1.2 0.67 9.8 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF479 PF04336.7 EMC86967.1 - 1.8 8.6 6.8 6.8 6.8 0.1 3.4 1 1 3 4 4 4 0 Protein of unknown function, DUF479 DUF16 PF01519.11 EMC86967.1 - 1.9 8.7 16.8 0.17 12.1 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.6 EMC86967.1 - 2.1 8.7 14.6 0.09 13.1 1.4 3.3 1 1 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 EMC86967.1 - 2.4 8.1 19.0 1.5 8.7 0.3 4.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.6 EMC86967.1 - 2.6 7.2 10.8 0.93 8.7 1.2 2.2 1 1 0 2 2 2 0 Allexivirus 40kDa protein WXG100 PF06013.7 EMC86967.1 - 3.2 7.8 9.1 11 6.0 0.1 3.8 4 1 0 4 4 3 0 Proteins of 100 residues with WXG Filo_VP35 PF02097.10 EMC86967.1 - 3.9 6.5 6.6 0.79 8.8 1.0 1.9 1 1 0 2 2 2 0 Filoviridae VP35 DUF4094 PF13334.1 EMC86967.1 - 4 7.8 6.2 1.4 9.3 0.2 3.0 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) TSC22 PF01166.13 EMC86967.1 - 4.2 7.4 8.2 4.1 7.4 0.0 2.9 3 0 0 3 3 2 0 TSC-22/dip/bun family FliT PF05400.8 EMC86967.1 - 4.5 7.7 7.8 0.8 10.1 0.8 2.6 2 1 0 2 2 2 0 Flagellar protein FliT FlxA PF14282.1 EMC86967.1 - 4.7 7.2 10.8 1.1 9.1 1.9 2.6 2 1 0 2 2 2 0 FlxA-like protein DUF972 PF06156.8 EMC86967.1 - 4.7 7.6 18.0 0.23 11.7 3.4 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF972) Phage_GPO PF05929.6 EMC86967.1 - 4.7 6.3 13.1 1.6 7.9 4.2 2.6 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Sec34 PF04136.10 EMC86967.1 - 5 6.8 8.8 0.64 9.7 1.9 2.3 1 1 0 2 2 2 0 Sec34-like family CM_2 PF01817.16 EMC86967.1 - 5.6 7.1 10.3 0.24 11.5 1.1 2.9 3 1 0 3 3 2 0 Chorismate mutase type II DUF904 PF06005.7 EMC86967.1 - 6.3 7.1 10.9 1.1 9.5 2.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) ETRAMP PF09716.5 EMC86967.1 - 6.3 6.8 9.1 1.2 9.0 0.8 2.9 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF883 PF05957.8 EMC86967.1 - 6.4 7.2 8.4 4.5 7.7 1.4 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 EMC86967.1 - 7 6.4 15.2 12 5.6 0.5 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EMC86967.1 - 9.2 6.0 16.7 17 5.1 4.6 3.7 1 1 2 3 3 3 0 Laminin Domain II GvpK PF05121.7 EMC86967.1 - 9.9 6.0 8.1 38 4.1 0.1 3.7 2 2 1 3 3 3 0 Gas vesicle protein K 7tm_2 PF00002.19 EMC86968.1 - 1.3e-51 175.0 20.1 1.3e-51 175.0 13.9 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Laminin_G_3 PF13385.1 EMC86968.1 - 2.1e-16 60.5 0.2 4.8e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.16 EMC86968.1 - 3e-12 46.4 1.4 8.2e-12 45.0 1.0 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Mycobact_memb PF05423.8 EMC86968.1 - 0.028 14.1 0.8 0.053 13.2 0.1 1.8 2 0 0 2 2 2 0 Mycobacterium membrane protein Peptidase_M10 PF00413.19 EMC86969.1 - 1.4e-47 161.2 0.6 2.6e-47 160.3 0.4 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC86969.1 - 8.9e-41 137.3 19.6 4e-12 45.6 0.2 5.1 5 0 0 5 5 5 4 Hemopexin PG_binding_1 PF01471.13 EMC86969.1 - 2.6e-14 52.9 0.2 7.1e-14 51.5 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 EMC86969.1 - 0.043 13.1 1.7 0.55 9.5 0.6 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.4 EMC86969.1 - 0.047 12.5 0.1 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Pkinase PF00069.20 EMC86970.1 - 1.8e-63 214.1 0.1 1.8e-63 214.1 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain DUF3543 PF12063.3 EMC86970.1 - 1.7e-46 158.4 7.7 2.8e-46 157.6 5.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 EMC86970.1 - 1.5e-45 155.3 0.1 2.5e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC86970.1 - 6.6e-06 25.3 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC86970.1 - 0.00011 21.3 0.0 0.00033 19.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC86970.1 - 0.00014 21.2 0.1 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMC86970.1 - 0.015 15.0 0.0 0.16 11.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC86970.1 - 0.031 13.8 0.3 8.5 5.8 0.0 2.8 2 1 1 3 3 3 0 Choline/ethanolamine kinase CBF PF03914.12 EMC86971.1 - 2.6e-49 166.8 0.4 4.4e-49 166.0 0.3 1.4 1 0 0 1 1 1 1 CBF/Mak21 family Glycos_transf_2 PF00535.21 EMC86972.1 - 1.4e-23 83.3 0.2 2.9e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC86972.1 - 4.6e-18 65.4 0.0 7.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC86972.1 - 3.7e-08 33.4 0.0 2.1e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC86972.1 - 0.0001 21.6 0.0 0.00026 20.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC86972.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Auts2 PF15336.1 EMC86973.1 - 7e-118 392.1 13.5 7e-118 392.1 9.4 5.3 5 1 1 6 6 6 1 Autism susceptibility gene 2 protein Ank_2 PF12796.2 EMC86975.1 - 3.3e-08 33.7 0.0 1.7e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC86975.1 - 9.7e-08 32.0 0.0 0.013 15.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) LEM PF03020.10 EMC86975.1 - 2.2e-07 30.2 0.0 5.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 LEM domain Ank PF00023.25 EMC86975.1 - 2.9e-07 29.9 0.0 0.00046 19.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EMC86975.1 - 4.7e-06 26.3 0.0 0.0016 18.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EMC86975.1 - 1e-05 25.9 0.0 6.3e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Cauli_VI PF01693.11 EMC86975.1 - 0.032 14.2 0.1 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Caulimovirus viroplasmin Reticulon PF02453.12 EMC86976.1 - 0.018 14.6 0.8 0.038 13.6 0.5 1.5 1 0 0 1 1 1 0 Reticulon ALMT PF11744.3 EMC86976.1 - 0.097 11.3 0.3 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter zf-C2H2_2 PF12756.2 EMC86977.1 - 5.1e-36 122.8 10.2 1.1e-28 99.3 0.2 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMC86977.1 - 1.5e-12 47.3 13.9 5.7e-09 35.8 1.8 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC86977.1 - 4.8e-05 23.4 3.3 4.8e-05 23.4 2.3 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EMC86977.1 - 0.0026 17.3 0.5 0.0026 17.3 0.3 3.0 3 0 0 3 3 3 1 DBF zinc finger zf-C2H2_4 PF13894.1 EMC86977.1 - 0.0065 16.7 1.3 0.0065 16.7 0.9 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger DUF629 PF04780.7 EMC86977.1 - 0.0077 14.7 0.5 0.0077 14.7 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 EMC86977.1 - 0.016 15.0 1.3 0.016 15.0 0.9 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger AKAP95 PF04988.7 EMC86977.1 - 1.2 8.9 14.3 2.1 8.1 0.0 3.9 3 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf-LYAR PF08790.6 EMC86977.1 - 4.8 6.9 7.6 8.3 6.2 0.2 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger TRAP_alpha PF03896.11 EMC86977.1 - 8.8 5.2 10.0 0.86 8.5 3.7 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RINGv PF12906.2 EMC86978.1 - 3e-10 39.9 3.6 3e-10 39.9 2.5 1.8 2 0 0 2 2 2 1 RING-variant domain ABC_cobalt PF09819.4 EMC86978.1 - 0.089 12.7 2.7 0.13 12.1 1.9 1.2 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component LRR_6 PF13516.1 EMC86979.1 - 6.5e-28 93.6 0.9 0.018 15.0 0.0 10.7 11 0 0 11 11 11 6 Leucine Rich repeat F-box-like PF12937.2 EMC86979.1 - 2.7e-17 62.1 4.3 7.9e-17 60.7 3.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EMC86979.1 - 5.1e-17 61.0 0.0 0.0043 16.6 0.0 6.7 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC86979.1 - 5.7e-17 59.1 6.7 0.39 10.9 0.0 10.8 10 1 1 11 11 11 3 Leucine Rich Repeat F-box PF00646.28 EMC86979.1 - 2.3e-12 46.1 2.1 2.3e-12 46.1 1.4 2.7 2 0 0 2 2 2 1 F-box domain LRR_7 PF13504.1 EMC86979.1 - 2.8e-12 44.6 10.7 1.6 9.2 0.0 10.0 10 1 0 10 10 10 2 Leucine rich repeat LRR_8 PF13855.1 EMC86979.1 - 1.3e-08 34.4 1.4 0.29 10.9 0.0 6.0 3 3 3 6 6 6 3 Leucine rich repeat TLE_N PF03920.10 EMC86980.1 - 1.3e-72 241.9 10.1 1.9e-72 241.3 7.0 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 EMC86980.1 - 4.1e-30 102.5 24.5 4.2e-08 32.7 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat HALZ PF02183.13 EMC86980.1 - 0.02 14.6 0.6 0.045 13.4 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Transketolase_N PF00456.16 EMC86980.1 - 0.068 11.9 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Cytochrom_D1 PF02239.11 EMC86980.1 - 0.068 11.4 0.0 1.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Aminotran_5 PF00266.14 EMC86981.1 - 3.1e-59 200.5 0.0 3.5e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V EGF_alliinase PF04863.8 EMC86981.1 - 0.05 13.5 0.4 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain VWD PF00094.20 EMC86982.1 - 1.1e-91 305.2 25.9 1.8e-32 112.7 2.0 4.8 5 0 0 5 5 5 3 von Willebrand factor type D domain C8 PF08742.6 EMC86982.1 - 2.6e-54 181.3 51.4 1.7e-21 76.2 11.0 6.2 7 1 0 7 7 7 3 C8 domain Mucin2_WxxW PF13330.1 EMC86982.1 - 2.9e-30 104.5 6.1 2e-21 76.1 2.0 5.4 7 0 0 7 7 7 2 Mucin-2 protein WxxW repeating region TIL PF01826.12 EMC86982.1 - 1.5e-15 57.0 57.4 1e-08 35.1 12.5 12.7 9 3 2 11 11 11 4 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 EMC86982.1 - 0.00029 20.8 20.7 0.00066 19.7 5.1 13.6 7 5 5 12 12 12 2 von Willebrand factor type C domain PTB PF08416.8 EMC86984.1 - 4.3e-30 104.3 0.0 6.3e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.19 EMC86984.1 - 1.6e-10 40.6 0.0 2.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 SH2 domain PID PF00640.18 EMC86984.1 - 0.0011 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Endostatin PF06482.6 EMC86985.1 - 3.3e-60 204.1 0.0 4.1e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Hormone_recep PF00104.25 EMC86986.1 - 0.0039 16.3 0.1 0.0067 15.5 0.1 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF3482 PF11981.3 EMC86986.1 - 0.13 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Cytochrom_NNT PF03264.9 EMC86986.1 - 0.14 11.6 0.1 0.17 11.3 0.1 1.0 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region zf-C4 PF00105.13 EMC86987.1 - 2.2e-34 117.4 16.1 2.5e-34 117.3 11.2 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PAN_3 PF08277.7 EMC86987.1 - 2.7 7.6 8.6 0.17 11.5 2.2 1.7 2 0 0 2 2 2 0 PAN-like domain C1_3 PF07649.7 EMC86987.1 - 7.3 6.7 12.0 1.5 8.9 2.5 3.1 3 0 0 3 3 3 0 C1-like domain EF-hand_1 PF00036.27 EMC86988.1 - 5.1e-18 62.9 6.6 6.1e-09 34.5 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EMC86988.1 - 9.8e-17 60.8 1.8 7e-14 51.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC86988.1 - 1.8e-15 55.3 2.1 2.5e-08 33.1 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EMC86988.1 - 2.4e-14 51.9 4.7 5.2e-06 25.5 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EMC86988.1 - 4.2e-13 48.6 8.1 8.3e-11 41.3 0.3 4.1 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 EMC86988.1 - 0.005 16.7 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EMC86988.1 - 0.0056 16.7 0.3 0.026 14.5 0.0 2.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC86988.1 - 0.014 15.0 0.2 0.034 13.8 0.1 1.6 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EMC86988.1 - 0.16 11.9 0.4 0.9 9.5 0.0 2.4 2 2 0 2 2 2 0 Ca2+ insensitive EF hand 7tm_4 PF13853.1 EMC86989.1 - 3.8e-31 107.8 6.1 3.8e-31 107.8 4.2 1.9 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC86989.1 - 1.1e-29 103.3 11.5 1.3e-29 103.1 8.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Apc3 PF12895.2 EMC86990.1 - 4.7e-27 93.9 12.1 1.4e-18 66.8 7.1 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EMC86990.1 - 1.1e-25 89.0 21.0 6.7e-14 51.2 0.1 7.3 6 2 0 8 8 8 5 TPR repeat TPR_2 PF07719.12 EMC86990.1 - 2.2e-25 86.4 17.5 6.8e-06 25.6 0.1 10.3 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 EMC86990.1 - 1e-21 75.5 19.4 4.1e-08 32.5 0.1 8.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMC86990.1 - 2.1e-21 75.6 0.7 4.8e-12 45.6 0.3 7.3 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC86990.1 - 1e-16 59.3 2.2 0.011 15.4 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC86990.1 - 4.6e-15 55.7 2.2 0.011 16.0 0.0 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC86990.1 - 3.9e-13 49.6 10.1 0.00023 21.7 0.0 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC86990.1 - 7.4e-13 47.2 7.2 1.8e-05 24.1 0.1 5.2 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC86990.1 - 1.4e-11 43.5 1.7 0.024 14.8 0.0 5.8 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMC86990.1 - 4.2e-11 42.4 0.4 0.00014 21.6 0.2 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC86990.1 - 4.7e-10 39.1 6.8 1.1 10.0 0.0 7.7 6 3 3 9 9 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMC86990.1 - 1.1e-07 31.6 5.7 0.0073 16.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 EMC86990.1 - 0.062 13.1 5.4 5.8 6.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat GFP PF01353.17 EMC86990.1 - 0.079 12.3 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Green fluorescent protein APC8 PF04049.8 EMC86990.1 - 0.095 12.4 3.5 0.16 11.7 1.6 2.0 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_6 PF13174.1 EMC86990.1 - 0.18 12.3 15.9 3 8.5 0.2 6.8 9 0 0 9 9 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC86990.1 - 0.54 10.1 9.3 0.98 9.3 0.2 4.2 4 1 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Laminin_G_1 PF00054.18 EMC86991.1 - 3.1e-29 101.6 0.0 1.3e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.19 EMC86991.1 - 1.9e-28 99.0 0.1 7.9e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.10 EMC86991.1 - 1.7e-19 69.5 50.6 6e-08 32.5 5.6 4.9 3 1 1 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.2 EMC86991.1 - 1.8e-11 43.4 32.8 9.6e-07 28.3 2.6 4.9 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.22 EMC86991.1 - 5.8e-10 38.9 40.4 0.00033 20.5 4.1 4.7 4 0 0 4 4 4 4 EGF-like domain FXa_inhibition PF14670.1 EMC86991.1 - 1.8e-07 31.1 47.6 0.0056 16.7 6.4 4.6 3 1 1 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EMC86991.1 - 7.1e-05 22.6 37.7 0.0034 17.3 2.1 4.9 3 1 1 4 4 4 3 EGF domain FAM70 PF14967.1 EMC86992.1 - 5.9e-177 587.7 8.5 6.6e-177 587.5 5.9 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.1 EMC86992.1 - 0.0043 17.1 11.0 0.17 11.9 4.9 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) DUF1097 PF06496.6 EMC86992.1 - 0.53 10.0 11.0 2.5 7.8 3.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1097) DUF2407_C PF13373.1 EMC86992.1 - 0.67 9.8 2.3 8.6 6.2 0.7 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain Na_K-ATPase PF00287.13 EMC86993.1 - 1.3e-101 339.1 0.6 1.5e-101 338.9 0.4 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DP PF08781.5 EMC86994.1 - 4.9e-60 201.3 2.1 1.1e-59 200.1 1.5 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.15 EMC86994.1 - 6.5e-27 92.9 0.3 1.4e-26 91.8 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Na_H_Exchanger PF00999.16 EMC86995.1 - 3e-73 246.5 42.8 4e-73 246.1 29.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF16 PF01519.11 EMC86995.1 - 2.6 8.2 5.8 5.1 7.3 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cullin_binding PF03556.10 EMC86996.1 - 2.5e-40 137.2 3.9 2.5e-40 137.2 0.5 2.2 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 EMC86996.1 - 1.9e-09 36.8 1.7 5.4e-09 35.4 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain PV_NSP1 PF12433.3 EMC86996.1 - 0.27 11.3 2.7 0.56 10.3 1.4 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein 1 ADP_ribosyl_GH PF03747.9 EMC86997.1 - 2.2e-42 145.8 0.0 2.6e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase TRH PF05438.7 EMC86998.1 - 0.007 15.7 0.9 0.007 15.7 0.7 1.5 1 1 1 2 2 2 1 Thyrotropin-releasing hormone (TRH) RabGAP-TBC PF00566.13 EMC87000.1 - 2.5e-56 190.5 0.1 3.6e-56 189.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lamp PF01299.12 EMC87001.1 - 6.7e-117 390.0 8.9 8e-112 373.3 4.6 2.1 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) Cullin PF00888.17 EMC87002.1 - 2.1e-174 581.3 21.2 3.1e-174 580.7 14.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMC87002.1 - 1.3e-26 92.2 0.2 5.1e-26 90.2 0.1 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Membr_traf_MHD PF10540.4 EMC87002.1 - 0.006 16.3 1.0 0.61 9.8 0.0 3.6 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain HTH_34 PF13601.1 EMC87002.1 - 0.019 14.9 0.0 0.92 9.5 0.0 2.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain PCI PF01399.22 EMC87003.1 - 1.8e-17 63.5 1.8 4.3e-17 62.3 1.3 1.7 1 0 0 1 1 1 1 PCI domain Trypsin PF00089.21 EMC87004.1 - 2.2e-20 73.1 0.0 3.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin FXa_inhibition PF14670.1 EMC87004.1 - 2.4e-10 40.3 28.0 1.2e-07 31.6 7.7 2.9 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site Gla PF00594.15 EMC87004.1 - 3.6e-09 36.1 7.5 7.4e-09 35.1 5.2 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain EGF PF00008.22 EMC87004.1 - 4.4e-08 32.9 8.6 4.4e-08 32.9 6.0 3.5 4 0 0 4 4 4 2 EGF-like domain cEGF PF12662.2 EMC87004.1 - 3.6e-06 26.4 16.0 7.3e-05 22.3 0.3 3.3 3 0 0 3 3 3 2 Complement Clr-like EGF-like hEGF PF12661.2 EMC87004.1 - 0.0013 18.6 6.6 0.021 14.8 1.7 3.3 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_CA PF07645.10 EMC87004.1 - 0.0034 17.3 31.6 0.039 13.9 5.9 3.1 2 1 1 3 3 3 2 Calcium-binding EGF domain DUF1986 PF09342.6 EMC87004.1 - 0.0085 15.4 0.0 0.0085 15.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) EGF_3 PF12947.2 EMC87004.1 - 0.54 10.2 21.0 0.22 11.5 4.5 3.0 2 1 0 2 2 2 0 EGF domain Trypsin PF00089.21 EMC87005.1 - 2e-58 197.6 0.0 2.2e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC87005.1 - 2.2e-05 23.8 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.21 EMC87006.1 - 6.2e-71 238.4 0.1 9.8e-71 237.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Gla PF00594.15 EMC87006.1 - 3.8e-17 61.6 11.0 8.6e-17 60.5 7.7 1.7 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.1 EMC87006.1 - 1.5e-09 37.8 29.4 1.8e-09 37.5 3.4 3.0 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 EMC87006.1 - 4.3e-07 29.7 11.5 4.3e-07 29.7 7.9 3.0 3 0 0 3 3 3 2 EGF-like domain DUF1986 PF09342.6 EMC87006.1 - 8.6e-07 28.5 0.0 2.6e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) cEGF PF12662.2 EMC87006.1 - 3e-06 26.7 16.2 0.0011 18.6 2.5 3.2 3 0 0 3 3 3 2 Complement Clr-like EGF-like Trypsin_2 PF13365.1 EMC87006.1 - 3.7e-05 23.6 0.0 9.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.2 EMC87006.1 - 0.015 15.3 6.5 0.058 13.4 1.7 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_3 PF12947.2 EMC87006.1 - 4 7.4 24.3 10 6.1 4.4 3.1 2 0 0 2 2 2 0 EGF domain Trypsin PF00089.21 EMC87007.1 - 1.2e-63 214.6 0.2 1.8e-63 214.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin Gla PF00594.15 EMC87007.1 - 7.8e-17 60.6 6.5 1.6e-16 59.6 4.5 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.1 EMC87007.1 - 4.2e-10 39.5 19.7 2.7e-09 36.9 4.1 2.8 1 1 1 2 2 2 2 Coagulation Factor Xa inhibitory site DUF1986 PF09342.6 EMC87007.1 - 3e-08 33.3 0.0 5.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF PF00008.22 EMC87007.1 - 2.4e-06 27.4 8.2 2.4e-06 27.4 5.7 3.1 3 0 0 3 3 3 1 EGF-like domain Trypsin_2 PF13365.1 EMC87007.1 - 0.0051 16.7 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 EMC87007.1 - 0.02 15.0 11.8 0.02 15.0 8.2 3.1 2 0 0 2 2 2 0 EGF-like domain RhoGEF PF00621.15 EMC87008.1 - 2.6e-39 134.9 5.9 2.6e-39 134.9 4.1 3.2 2 1 0 2 2 2 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 EMC87008.1 - 9.9e-16 57.9 0.0 2.8e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.24 EMC87008.1 - 6.2e-07 29.5 0.1 2e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EMC87008.1 - 2e-06 27.0 0.1 2e-06 27.0 0.1 2.1 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EMC87008.1 - 1.8e-05 24.1 1.1 7.6e-05 22.2 0.1 2.5 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EMC87008.1 - 5.2e-05 22.6 0.0 0.00013 21.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Spectrin PF00435.16 EMC87008.1 - 0.00016 21.9 19.3 0.0094 16.2 0.0 5.2 4 2 1 5 5 5 2 Spectrin repeat E1-E2_ATPase PF00122.15 EMC87009.1 - 4.8e-19 68.3 0.0 4.6e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EMC87009.1 - 1.4e-18 67.7 0.0 4.5e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC87009.1 - 3.3e-14 53.8 1.5 1.6e-10 41.7 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC87009.1 - 1.5e-11 44.0 0.1 1.2e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMC87009.1 - 0.00053 19.6 0.0 0.075 12.6 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4014 PF13198.1 EMC87009.1 - 0.25 11.7 4.6 1 9.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) Spc97_Spc98 PF04130.8 EMC87010.1 - 4.4e-127 424.6 7.3 6.3e-127 424.1 5.1 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family PT PF04886.7 EMC87011.1 - 0.022 14.0 1.6 5.3 6.4 0.0 4.5 5 0 0 5 5 5 0 PT repeat HECT PF00632.20 EMC87012.1 - 3.2e-47 161.2 0.1 3.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Phage_fiber_C PF06820.7 EMC87013.1 - 0.11 12.6 0.6 1.2e+02 2.9 0.0 4.4 1 1 5 6 6 6 0 Putative prophage tail fibre C-terminus Suf PF05843.9 EMC87015.1 - 0.0008 19.2 0.0 0.00093 19.0 0.0 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EMC87015.1 - 0.031 13.3 0.0 0.035 13.1 0.0 1.0 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_8 PF13855.1 EMC87016.1 - 1.8e-28 98.0 14.4 7.3e-11 41.6 0.7 4.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EMC87016.1 - 3e-19 68.2 13.0 2e-05 24.0 1.7 5.0 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) I-set PF07679.11 EMC87016.1 - 2.2e-16 59.4 0.0 3.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 EMC87016.1 - 3.1e-13 49.5 0.5 1.3e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC87016.1 - 1.1e-11 43.0 19.1 0.12 12.4 0.7 7.9 9 0 0 9 9 8 5 Leucine Rich Repeat Ig_2 PF13895.1 EMC87016.1 - 4e-10 39.6 0.0 8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC87016.1 - 5.7e-09 36.3 0.0 1.7e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 EMC87016.1 - 8.1e-06 25.8 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.20 EMC87016.1 - 1.5e-05 24.9 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 EMC87016.1 - 0.0017 17.9 2.7 0.013 15.0 0.4 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 EMC87016.1 - 0.017 15.2 19.7 6.5 7.4 0.2 7.7 8 0 0 8 8 8 0 Leucine rich repeat V-set PF07686.12 EMC87016.1 - 0.02 14.7 0.0 0.076 12.9 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRR_6 PF13516.1 EMC87016.1 - 1.1 9.5 22.6 2.7 8.3 0.7 5.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_3 PF07725.7 EMC87016.1 - 6.7 6.6 7.7 28 4.7 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat TPMT PF05724.6 EMC87017.1 - 5.5e-64 215.5 0.0 6.1e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EMC87017.1 - 0.0015 19.1 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC87017.1 - 0.011 15.2 0.0 0.082 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Amino_oxidase PF01593.19 EMC87018.1 - 4.1e-91 306.3 0.0 1.3e-90 304.6 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase zf-CW PF07496.10 EMC87018.1 - 1.7e-12 46.8 2.0 5.2e-12 45.2 1.4 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger NAD_binding_8 PF13450.1 EMC87018.1 - 1.1e-11 44.5 0.2 2.7e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC87018.1 - 1.2e-10 40.8 0.1 6.8e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMC87018.1 - 3.8e-09 35.9 0.1 1.9e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EMC87018.1 - 1e-08 35.4 1.8 1.6e-05 25.1 0.7 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC87018.1 - 7.5e-07 29.4 0.6 0.00013 22.3 0.2 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC87018.1 - 2.6e-06 26.1 1.7 2.3e-05 23.0 0.5 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 EMC87018.1 - 3e-06 26.3 0.9 1.3e-05 24.2 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EMC87018.1 - 5.8e-06 25.5 0.3 5.5e-05 22.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC87018.1 - 7.3e-06 25.9 1.3 4.3e-05 23.4 0.7 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SWIRM PF04433.12 EMC87018.1 - 1e-05 25.5 0.1 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Lycopene_cycl PF05834.7 EMC87018.1 - 0.00013 21.0 0.2 0.00073 18.5 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EMC87018.1 - 0.00017 20.7 0.0 0.00065 18.8 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMC87018.1 - 0.00021 20.4 0.2 0.00037 19.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMC87018.1 - 0.0005 19.0 0.8 0.00083 18.3 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EMC87018.1 - 0.0013 18.5 0.8 0.14 11.9 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding zf-RING_2 PF13639.1 EMC87018.1 - 0.0019 17.9 4.2 0.006 16.3 2.9 1.9 1 0 0 1 1 1 1 Ring finger domain Shikimate_DH PF01488.15 EMC87018.1 - 0.0054 16.8 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EMC87018.1 - 0.0081 15.5 0.3 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EMC87018.1 - 0.0097 15.7 0.2 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.16 EMC87018.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EMC87018.1 - 0.071 13.3 1.5 0.23 11.7 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding zf-C3HC4 PF00097.20 EMC87018.1 - 0.085 12.5 4.0 0.32 10.6 2.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Malic_M PF03949.10 EMC87018.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain CPSase_L_chain PF00289.17 EMC87018.1 - 0.19 11.8 0.2 0.51 10.4 0.1 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain DEK_C PF08766.6 EMC87019.1 - 1.1e-18 66.7 0.7 2.3e-18 65.7 0.5 1.6 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.22 EMC87019.1 - 4.8e-06 25.9 1.4 1.5e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 SAP domain MIP-T3 PF10243.4 EMC87019.1 - 0.76 8.1 52.0 0.051 12.0 20.7 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EMC87019.1 - 7.9 4.8 42.6 4.6 5.6 15.4 2.1 2 0 0 2 2 2 0 Daxx Family FLO_LFY PF01698.11 EMC87019.1 - 9 5.0 23.5 3.5 6.3 7.8 2.4 2 0 0 2 2 2 0 Floricaula / Leafy protein IBR PF01485.16 EMC87020.1 - 1e-18 66.9 21.7 6.8e-13 48.2 5.5 5.1 4 1 1 5 5 5 2 IBR domain zf-RING_2 PF13639.1 EMC87020.1 - 0.00038 20.2 11.5 0.00038 20.2 8.0 4.4 3 1 1 4 4 4 3 Ring finger domain HLH PF00010.21 EMC87021.1 - 5.2e-06 26.0 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MBOAT PF03062.14 EMC87022.1 - 4.4e-31 108.1 9.7 4.4e-31 108.1 6.7 2.1 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family E2F_TDP PF02319.15 EMC87023.1 - 1.5e-25 88.5 0.2 3.3e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain UPF0004 PF00919.15 EMC87024.1 - 4.4e-21 74.5 0.0 9.2e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.16 EMC87024.1 - 8.6e-20 71.5 0.1 2.7e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.15 EMC87024.1 - 3.8e-06 26.5 0.0 8.3e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Hormone_1 PF00103.15 EMC87026.1 - 5.3e-74 248.1 0.0 6e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Neurensin PF14927.1 EMC87027.1 - 7.5e-52 174.4 0.0 9.2e-52 174.1 0.0 1.1 1 0 0 1 1 1 1 Neurensin DUF624 PF04854.9 EMC87027.1 - 0.033 14.0 0.9 0.14 12.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF624 DUF3995 PF13160.1 EMC87027.1 - 0.034 14.1 0.6 1.9 8.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) COX8 PF02285.10 EMC87027.1 - 0.22 11.0 1.0 0.46 10.0 0.7 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII DCX PF03607.12 EMC87028.1 - 2.3e-43 145.5 0.0 1.6e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 Doublecortin FG-GAP PF01839.18 EMC87030.1 - 7.3e-23 79.6 30.0 2.7e-07 30.0 0.3 5.9 5 0 0 5 5 5 4 FG-GAP repeat Zn_dep_PLPC PF00882.13 EMC87030.1 - 1.9e-20 73.1 2.5 4.1e-20 72.0 1.8 1.6 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.1 EMC87030.1 - 4.5e-15 55.7 10.9 3e-07 30.6 0.9 5.0 2 1 2 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EMC87030.1 - 0.00011 21.6 0.5 0.03 13.7 0.0 3.4 3 1 1 4 4 4 1 Insecticide toxin TcdB middle/N-terminal region Aldedh PF00171.17 EMC87031.1 - 2.4e-149 497.6 1.4 2.7e-149 497.4 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Y_Y_Y PF07495.8 EMC87032.1 - 4.7e-18 64.6 0.0 0.001 18.7 0.0 5.5 5 0 0 5 5 5 4 Y_Y_Y domain REJ PF02010.10 EMC87032.1 - 2.9e-16 58.8 2.0 1.8e-06 26.6 0.0 4.2 1 1 2 3 3 3 3 REJ domain PKD PF00801.15 EMC87032.1 - 6.7e-13 48.1 6.5 0.057 13.1 0.1 5.6 5 0 0 5 5 5 4 PKD domain DUF4625 PF15418.1 EMC87032.1 - 3.3e-09 36.9 0.0 0.67 10.0 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) Big_3_4 PF13754.1 EMC87032.1 - 1.1e-08 35.2 5.7 0.064 13.5 0.0 4.9 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 3) He_PIG PF05345.7 EMC87032.1 - 1.7e-06 27.9 4.0 5.9 6.9 0.0 5.0 5 0 0 5 5 5 2 Putative Ig domain Big_2 PF02368.13 EMC87032.1 - 0.00017 21.4 0.6 0.22 11.4 0.0 3.5 3 0 0 3 3 3 2 Bacterial Ig-like domain (group 2) Cadherin PF00028.12 EMC87032.1 - 0.0046 17.1 2.3 7.2 6.9 0.2 4.2 3 1 0 3 3 3 1 Cadherin domain PA14 PF07691.7 EMC87032.1 - 0.011 15.3 0.7 4.9 6.7 0.0 4.4 4 1 0 4 4 4 0 PA14 domain Shisa PF13908.1 EMC87032.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EGF_2 PF07974.8 EMC87032.1 - 0.026 14.6 2.8 0.026 14.6 1.9 1.7 2 0 0 2 2 1 0 EGF-like domain DUF1180 PF06679.7 EMC87032.1 - 0.066 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SieB PF14163.1 EMC87032.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B Sec7 PF01369.15 EMC87033.1 - 1.5e-72 243.2 0.6 4.3e-72 241.7 0.4 1.8 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.5 EMC87033.1 - 7.3e-32 108.7 0.1 7.3e-32 108.7 0.1 4.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 EMC87033.1 - 4.7e-14 52.1 0.6 4.7e-14 52.1 0.4 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Rep_trans PF02486.14 EMC87033.1 - 0.086 12.3 1.1 0.29 10.6 0.4 2.1 2 0 0 2 2 2 0 Replication initiation factor CAF-1_p150 PF11600.3 EMC87034.1 - 0.00014 21.2 38.0 0.00014 21.2 26.3 6.5 6 1 0 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal CCDC66 PF15236.1 EMC87034.1 - 0.00057 19.5 39.2 0.00057 19.5 27.2 8.5 9 2 1 10 10 10 2 Coiled-coil domain-containing protein 66 JAB PF01398.16 EMC87035.1 - 2.1e-32 111.2 0.0 3.1e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMC87035.1 - 1.1e-06 28.1 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EMC87035.1 - 0.0039 16.7 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.2 EMC87036.1 - 4.1e-26 90.0 45.2 6.3e-08 32.0 1.8 5.2 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC87036.1 - 5.7e-15 54.8 22.7 3.6e-06 26.6 2.6 4.4 2 2 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EMC87036.1 - 1e-11 43.1 22.7 0.43 10.8 0.1 7.3 6 2 0 6 6 6 5 Leucine Rich Repeat LRR_9 PF14580.1 EMC87036.1 - 1.1e-09 38.1 9.4 7.1e-05 22.4 0.3 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EMC87036.1 - 2.7e-09 36.1 24.9 0.33 11.1 0.0 6.8 6 3 1 7 7 7 5 Leucine Rich repeat LRR_7 PF13504.1 EMC87036.1 - 4.9e-06 25.8 16.1 0.87 10.0 0.0 7.0 7 0 0 7 7 7 3 Leucine rich repeat FNIP PF05725.7 EMC87036.1 - 2.6 8.0 10.0 5 7.1 4.0 3.0 2 1 0 2 2 2 0 FNIP Repeat HLH PF00010.21 EMC87037.1 - 1.1e-12 47.3 0.0 1.3e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MCM PF00493.18 EMC87038.1 - 2.1e-17 62.9 0.1 1.1e-16 60.5 0.0 1.9 1 1 0 1 1 1 1 MCM2/3/5 family Pkinase PF00069.20 EMC87039.1 - 4.1e-66 222.7 0.0 5.2e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87039.1 - 2.7e-34 118.4 0.0 4e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 EMC87039.1 - 1.6e-20 72.9 0.2 4.3e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 PX domain Pkinase_C PF00433.19 EMC87039.1 - 3.4e-05 24.2 1.4 0.00055 20.4 0.1 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC87039.1 - 7.7e-05 21.7 0.0 0.00019 20.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC87039.1 - 0.0086 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC87039.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cmyb_C PF09316.5 EMC87040.1 - 7.9e-69 230.5 3.2 7.9e-69 230.5 2.2 2.0 2 0 0 2 2 2 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 EMC87040.1 - 2.5e-51 171.5 16.2 2.5e-17 62.6 1.4 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC87040.1 - 5.7e-42 141.6 20.2 4.6e-19 68.2 1.2 4.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMSTEN PF07988.7 EMC87040.1 - 1.8e-24 84.7 0.6 3.7e-24 83.7 0.4 1.6 1 0 0 1 1 1 1 LMSTEN motif Sigma70_r4_2 PF08281.7 EMC87040.1 - 0.024 14.0 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Rap1_C PF11626.3 EMC87040.1 - 0.33 10.8 11.0 47 3.9 4.7 3.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4648 PF15505.1 EMC87041.1 - 5e-34 117.9 0.1 5.3e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4648) Fe-ADH PF00465.14 EMC87042.1 - 8.1e-104 347.1 0.0 9.6e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMC87042.1 - 3.6e-15 55.9 0.0 2e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EMC87042.1 - 0.0039 16.5 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein CRF PF00473.12 EMC87043.1 - 2e-17 62.9 1.1 4.6e-17 61.8 0.7 1.6 1 0 0 1 1 1 1 Corticotropin-releasing factor family UCN2 PF11613.3 EMC87043.1 - 0.017 15.0 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 Elongin_A PF06881.6 EMC87043.1 - 0.024 14.9 0.1 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C3HC4_2 PF13923.1 EMC87044.1 - 7e-10 38.7 5.2 7e-10 38.7 3.6 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC87044.1 - 5.6e-09 35.5 4.4 8.1e-09 35.0 1.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMC87044.1 - 2e-08 33.9 4.7 2e-08 33.9 3.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC87044.1 - 5e-08 32.4 4.2 5e-08 32.4 2.9 2.7 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC87044.1 - 6e-08 32.2 3.6 6e-08 32.2 2.5 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87044.1 - 7.7e-07 28.7 4.7 7.7e-07 28.7 3.3 2.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC87044.1 - 1.3e-05 24.9 7.3 1.3e-05 24.9 5.0 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EMC87044.1 - 2.3e-05 24.0 0.4 2.3e-05 24.0 0.3 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-B_box PF00643.19 EMC87044.1 - 4.5e-05 23.2 9.6 4.5e-05 23.2 6.7 3.9 4 0 0 4 4 4 1 B-box zinc finger DUF1886 PF09171.5 EMC87044.1 - 0.06 12.3 0.3 0.13 11.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1886) Flagellin_C PF00700.16 EMC87044.1 - 0.083 13.0 0.1 0.29 11.3 0.1 1.9 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region RPW8 PF05659.6 EMC87044.1 - 0.38 10.2 4.2 0.58 9.6 2.3 1.7 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DnaJ PF00226.26 EMC87045.1 - 8.4e-26 89.4 3.0 1.4e-25 88.7 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain GP41 PF00517.12 EMC87045.1 - 0.073 12.6 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Retroviral envelope protein Mito_fiss_reg PF05308.6 EMC87046.1 - 2.6e-85 285.8 5.8 4e-85 285.2 4.0 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator FlxA PF14282.1 EMC87046.1 - 0.0082 16.0 0.8 0.023 14.6 0.6 1.7 1 0 0 1 1 1 1 FlxA-like protein DUF4391 PF14335.1 EMC87046.1 - 0.042 13.2 0.1 0.071 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Totivirus_coat PF05518.6 EMC87046.1 - 0.4 8.4 4.5 0.51 8.0 3.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein Arm PF00514.18 EMC87047.1 - 2.3e-05 24.0 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.21 EMC87047.1 - 0.0022 18.0 0.2 0.0046 17.0 0.2 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain HEAT_2 PF13646.1 EMC87047.1 - 0.061 13.6 0.1 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats p450 PF00067.17 EMC87048.1 - 1.1e-51 175.8 0.3 1.4e-51 175.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 YTH PF04146.10 EMC87049.1 - 1.1e-47 161.1 0.1 1.6e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain Channel_Tsx PF03502.8 EMC87049.1 - 0.02 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx PAT1 PF09770.4 EMC87049.1 - 6.2 4.9 26.0 9.4 4.3 18.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRAL_TRIO PF00650.15 EMC87050.1 - 1.1e-31 109.4 0.0 1.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain NARG2_C PF10505.4 EMC87050.1 - 0.03 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus Peptidase_C26 PF07722.8 EMC87051.1 - 3.2e-35 121.5 0.0 4.5e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EMC87051.1 - 5.6e-10 38.9 0.0 7.3e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NKAIN PF05640.9 EMC87052.1 - 6e-85 283.2 10.7 6.6e-85 283.1 7.4 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.6 EMC87052.1 - 0.025 14.4 0.3 0.046 13.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) CRAL_TRIO PF00650.15 EMC87053.1 - 1.5e-34 118.7 0.0 2.3e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC87053.1 - 1.7e-09 37.6 0.1 4.7e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMC87053.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SNF2_N PF00176.18 EMC87054.1 - 9.6e-70 234.7 0.2 1.5e-69 234.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain BRK PF07533.11 EMC87054.1 - 3.6e-42 141.5 3.5 1.5e-20 72.3 0.4 2.6 2 0 0 2 2 2 2 BRK domain Chromo PF00385.19 EMC87054.1 - 2.8e-24 84.5 8.0 2.8e-12 46.0 0.3 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EMC87054.1 - 4.8e-13 48.7 0.0 1.5e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ras PF00071.17 EMC87055.1 - 3.5e-59 198.8 0.1 4.3e-59 198.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC87055.1 - 3.8e-16 59.6 0.0 7.8e-16 58.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC87055.1 - 5.8e-12 45.1 0.0 7.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC87055.1 - 0.00053 19.2 0.0 0.00066 18.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC87055.1 - 0.00082 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Carb_anhydrase PF00194.16 EMC87056.1 - 7.9e-97 323.2 0.0 8.7e-97 323.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HMG_box PF00505.14 EMC87057.1 - 6.2e-18 64.8 0.5 1.4e-17 63.7 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC87057.1 - 3.9e-12 46.3 0.8 7.3e-12 45.4 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 EMC87057.1 - 1.9 8.7 7.4 0.27 11.4 0.3 2.6 2 1 1 3 3 3 0 YABBY protein Beach PF02138.13 EMC87058.1 - 2.7e-103 345.0 0.0 4.9e-103 344.2 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EMC87058.1 - 1.8e-24 84.6 18.7 2.1e-06 27.4 0.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat GRAM PF02893.15 EMC87058.1 - 3.8e-10 39.1 0.1 3.9e-09 35.8 0.0 2.7 3 0 0 3 3 3 1 GRAM domain PH_BEACH PF14844.1 EMC87058.1 - 7.5e-10 38.6 0.0 2.8e-06 27.1 0.0 3.6 2 2 0 2 2 2 2 PH domain associated with Beige/BEACH PDZ PF00595.19 EMC87059.1 - 3.4e-21 75.1 2.2 5.4e-13 48.9 0.1 3.0 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC87059.1 - 1.4e-11 44.1 0.3 5.4e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 PDZ domain p450 PF00067.17 EMC87060.1 - 9.9e-79 264.9 1.3 1.2e-78 264.7 0.9 1.0 1 0 0 1 1 1 1 Cytochrome P450 SEP PF08059.8 EMC87061.1 - 1e-29 102.6 0.7 2.4e-29 101.4 0.1 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EMC87061.1 - 3.8e-19 68.5 0.3 6.9e-19 67.6 0.2 1.5 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 EMC87061.1 - 0.0022 17.3 0.1 0.005 16.2 0.0 1.7 1 1 0 1 1 1 1 Spt20 family FAM110_N PF14161.1 EMC87062.1 - 1.3e-52 176.6 5.2 1.3e-52 176.6 3.6 2.1 2 0 0 2 2 2 1 Centrosome-associated N terminus FAM110_C PF14160.1 EMC87062.1 - 2.4e-47 160.5 1.5 2.4e-47 160.5 1.1 2.2 3 0 0 3 3 3 1 Centrosome-associated C terminus adh_short PF00106.20 EMC87063.1 - 6.5e-30 104.2 0.2 8e-30 103.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC87063.1 - 2.3e-11 43.9 0.0 3.1e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC87063.1 - 3.5e-11 43.1 0.2 5.2e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMC87063.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EMC87063.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EMC87063.1 - 0.042 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EMC87063.1 - 0.1 12.0 0.1 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EMC87063.1 - 0.13 12.2 0.4 0.84 9.6 0.3 2.0 1 1 0 1 1 1 0 NADH(P)-binding DUF1903 PF08991.5 EMC87064.1 - 0.00012 22.1 0.7 0.00015 21.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CEP1-DNA_bind PF09287.5 EMC87064.1 - 0.00054 19.4 0.1 0.00067 19.1 0.1 1.1 1 0 0 1 1 1 1 CEP-1, DNA binding CHCH PF06747.8 EMC87064.1 - 0.15 12.0 5.3 0.22 11.4 3.7 1.3 1 0 0 1 1 1 0 CHCH domain zf-H2C2_2 PF13465.1 EMC87065.1 - 3.1e-28 96.6 57.8 2.6e-05 24.3 0.7 8.5 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87065.1 - 3.6e-23 80.4 64.6 0.00018 21.6 1.0 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87065.1 - 2.3e-20 71.3 54.2 0.00052 20.1 1.7 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC87065.1 - 2e-07 30.9 46.2 0.04 14.0 1.0 7.2 7 1 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC87065.1 - 9.8e-06 25.2 31.9 0.0015 18.3 0.1 6.7 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.2 EMC87065.1 - 0.0002 21.4 28.0 0.59 10.4 0.3 5.9 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC87065.1 - 0.038 14.1 40.5 0.79 9.8 1.1 5.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EMC87065.1 - 3.1 8.0 37.1 0.34 11.0 0.3 5.2 2 1 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 EMC87065.1 - 4.8 6.7 23.7 0.3 10.5 1.3 5.4 4 2 2 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Pkinase PF00069.20 EMC87066.1 - 2.7e-57 193.8 0.0 3.3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87066.1 - 6.4e-42 143.4 0.0 7.6e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87066.1 - 0.0039 16.1 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ribosomal_S10 PF00338.17 EMC87067.1 - 5.4e-34 115.9 0.4 6.3e-34 115.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkinase_Tyr PF07714.12 EMC87068.1 - 1.5e-97 325.7 0.0 1.9e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC87068.1 - 1.3e-50 171.9 0.0 1.9e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC87068.1 - 1.6e-24 85.5 0.0 3.3e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC87068.1 - 6.1e-17 60.7 0.1 1.4e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC87068.1 - 6.9e-12 44.7 0.0 1.8e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC87068.1 - 1.3e-09 37.3 0.5 3.8e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Acyltransferase PF01553.16 EMC87069.1 - 1.7e-07 30.7 0.0 7.7e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.8 EMC87069.1 - 0.0001 21.1 0.1 0.00021 20.0 0.0 1.5 2 0 0 2 2 2 1 Diacylglycerol acyltransferase XK-related PF09815.4 EMC87070.1 - 1.7e-105 352.6 24.5 2e-105 352.4 17.0 1.0 1 0 0 1 1 1 1 XK-related protein PLAT PF01477.18 EMC87072.1 - 2.7e-18 66.4 0.0 4.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain DCX PF03607.12 EMC87073.1 - 2.3e-39 132.7 0.0 8.3e-22 76.5 0.0 2.5 2 0 0 2 2 2 2 Doublecortin HMG_box PF00505.14 EMC87074.1 - 1.9e-11 44.0 0.0 2.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC87074.1 - 0.026 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 HMG-box domain Ribosomal_L18e PF00828.14 EMC87075.1 - 8.2e-13 48.8 1.7 4.7e-12 46.3 1.2 2.2 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_2 PF02230.11 EMC87076.1 - 2.8e-72 242.6 0.0 3.1e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMC87076.1 - 3.6e-11 42.9 0.0 4.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC87076.1 - 2e-07 31.1 0.0 1.9e-06 27.9 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMC87076.1 - 1.2e-06 28.3 0.0 2.6e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EMC87076.1 - 0.00013 21.5 0.0 0.00022 20.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC87076.1 - 0.0004 19.6 0.0 0.78 8.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Cutinase PF01083.17 EMC87076.1 - 0.00043 20.0 0.1 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 EMC87076.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.13 EMC87076.1 - 0.0031 16.8 0.0 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EMC87076.1 - 0.0037 16.7 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EMC87076.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 EMC87076.1 - 0.052 12.9 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 EMC87076.1 - 0.16 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RGS PF00615.14 EMC87077.1 - 1.1e-34 119.0 1.3 1.5e-34 118.6 0.9 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain V-ATPase_H_N PF03224.9 EMC87078.1 - 1.1e-103 346.5 9.6 1.8e-103 345.9 4.9 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EMC87078.1 - 1.8e-48 163.3 0.4 1.8e-48 163.3 0.3 2.7 3 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.18 EMC87078.1 - 1.1e-07 31.3 0.8 0.0031 17.2 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EMC87078.1 - 5.6e-05 22.3 0.6 0.0003 19.9 0.0 2.2 3 0 0 3 3 3 1 Armadillo-like Adaptin_N PF01602.15 EMC87078.1 - 0.00029 19.3 3.3 0.0011 17.4 0.1 2.7 3 0 0 3 3 3 1 Adaptin N terminal region UCH PF00443.24 EMC87078.1 - 0.0019 17.3 1.4 0.0021 17.2 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3826 PF12875.2 EMC87078.1 - 0.0036 17.0 0.6 0.0087 15.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) YlbD_coat PF14071.1 EMC87078.1 - 0.0058 16.6 1.0 0.0058 16.6 0.7 2.5 3 0 0 3 3 3 1 Putative coat protein HEAT PF02985.17 EMC87078.1 - 0.013 15.5 0.1 0.67 10.1 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Cnd1 PF12717.2 EMC87078.1 - 0.09 12.6 4.2 3.2 7.5 0.0 3.4 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF2326 PF10088.4 EMC87078.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2326) CcdB PF01845.12 EMC87078.1 - 0.12 12.2 0.3 1.6 8.6 0.0 2.9 4 0 0 4 4 4 0 CcdB protein CP2 PF04516.10 EMC87079.1 - 1.6e-44 151.7 0.0 1.8e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 CP2 transcription factor LEM PF03020.10 EMC87081.1 - 3.6e-10 39.1 0.1 7.7e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 LEM domain Abhydrolase_6 PF12697.2 EMC87082.1 - 1.2e-35 123.5 0.0 1.6e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC87082.1 - 3.5e-21 75.8 0.2 8.8e-14 51.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC87082.1 - 3.1e-19 69.1 0.1 1.5e-18 66.9 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMC87082.1 - 7e-07 29.0 0.2 5e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EMC87082.1 - 6.2e-05 22.5 0.4 0.24 10.8 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 EMC87082.1 - 0.018 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.16 EMC87082.1 - 0.02 14.1 0.0 0.17 11.0 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 EMC87082.1 - 0.021 14.2 0.0 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.13 EMC87082.1 - 0.03 13.6 0.0 4.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.9 EMC87082.1 - 0.068 11.6 0.0 0.97 7.8 0.0 2.0 2 0 0 2 2 2 0 Ndr family Abhydrolase_8 PF06259.7 EMC87082.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.20 EMC87082.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.8 EMC87082.1 - 0.16 11.5 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.6 EMC87082.1 - 0.17 11.6 0.0 1.6 8.4 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ribosomal_L34 PF00468.12 EMC87083.1 - 4.2e-20 71.1 2.3 4.2e-20 71.1 1.6 1.2 1 1 0 1 1 1 1 Ribosomal protein L34 DDA1 PF10172.4 EMC87084.1 - 1.1e-35 121.3 0.2 1.5e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase Anoctamin PF04547.7 EMC87085.1 - 1.3e-62 211.9 0.1 1.8e-62 211.5 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel MMR_HSR1 PF01926.18 EMC87087.1 - 2.8e-05 24.0 0.1 0.00011 22.1 0.1 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC87087.1 - 0.0007 18.8 0.0 0.11 11.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FeoB_N PF02421.13 EMC87087.1 - 0.0031 16.8 0.0 0.019 14.2 0.0 2.0 1 1 1 2 2 2 1 Ferrous iron transport protein B AAA_25 PF13481.1 EMC87087.1 - 0.034 13.5 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 EMC87087.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 EMC87087.1 - 0.16 12.7 0.0 0.33 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain YjeF_N PF03853.10 EMC87088.1 - 5.1e-12 45.7 0.0 1.8e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 YjeF-related protein N-terminus GATA PF00320.22 EMC87089.1 - 5.4e-05 22.4 6.9 0.00012 21.2 4.7 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF2299 PF10061.4 EMC87089.1 - 0.12 11.8 0.7 0.24 10.8 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) Cohesin_load PF10345.4 EMC87090.1 - 3.7e-102 342.5 13.7 4.4e-102 342.2 9.5 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_11 PF13414.1 EMC87090.1 - 6.1e-11 41.8 7.8 0.00066 19.2 0.0 4.9 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 EMC87090.1 - 2.3e-10 40.2 11.2 0.00053 19.8 0.0 5.5 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC87090.1 - 9.6e-08 31.3 5.3 0.16 11.9 0.1 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87090.1 - 0.00015 21.2 4.8 0.6 10.0 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87090.1 - 0.00016 22.0 1.5 1.1 10.0 0.0 6.0 5 2 2 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC87090.1 - 0.00052 20.0 5.8 0.37 10.9 0.0 4.4 3 2 3 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMC87090.1 - 0.0024 17.3 5.1 1.5 8.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat HemY_N PF07219.8 EMC87090.1 - 0.0027 17.2 0.1 0.021 14.3 0.0 2.4 2 1 0 2 2 2 1 HemY protein N-terminus TPR_10 PF13374.1 EMC87090.1 - 0.0098 15.8 0.2 2 8.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87090.1 - 0.062 13.6 4.8 2.8 8.3 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMC87090.1 - 0.09 12.7 0.3 7.7 6.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Cupin_7 PF12973.2 EMC87090.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 ChrR Cupin-like domain Surp PF01805.15 EMC87091.1 - 7.7e-23 79.9 3.2 6.1e-14 51.4 0.1 2.6 2 0 0 2 2 2 2 Surp module G-patch PF01585.18 EMC87091.1 - 5.3e-15 54.9 3.0 5.3e-15 54.9 2.1 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EMC87091.1 - 1.4e-08 34.4 2.1 1.8e-07 30.8 0.3 2.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site SOBP PF15279.1 EMC87091.1 - 5.2e-05 23.7 4.2 5.2e-05 23.7 2.9 3.5 2 1 1 3 3 3 1 Sine oculis-binding protein RtcB PF01139.12 EMC87091.1 - 0.08 11.9 1.0 0.12 11.3 0.7 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB DUF2781 PF10914.3 EMC87092.1 - 3.6e-37 127.4 15.8 5e-35 120.4 6.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2781) F5_F8_type_C PF00754.20 EMC87093.1 - 7.4e-05 22.5 0.0 0.00017 21.3 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain RasGAP_C PF03836.10 EMC87094.1 - 0.016 14.9 0.1 0.017 14.7 0.1 1.0 1 0 0 1 1 1 0 RasGAP C-terminus NEP PF10167.4 EMC87095.1 - 2.2e-28 98.3 0.0 2.3e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Jiraiya PF15038.1 EMC87096.1 - 4.9e-41 140.0 8.5 1e-40 139.0 5.9 1.5 1 1 0 1 1 1 1 Jiraiya DUF2215 PF10225.4 EMC87096.1 - 0.028 13.8 0.2 0.1 12.0 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF1469 PF07332.6 EMC87096.1 - 0.052 13.2 3.5 0.088 12.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3481 PF11980.3 EMC87096.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) TRP PF06011.7 EMC87096.1 - 0.87 8.0 3.4 1.6 7.2 2.4 1.5 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Tmemb_161AB PF10268.4 EMC87098.1 - 4.4e-220 731.2 0.6 5.8e-220 730.8 0.4 1.2 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Arm PF00514.18 EMC87100.1 - 1.4e-10 40.6 5.4 0.059 13.2 0.0 5.7 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EMC87100.1 - 0.0037 16.9 3.6 0.44 10.3 0.1 4.5 3 1 2 5 5 5 2 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.3 EMC87100.1 - 0.031 13.9 0.5 0.19 11.3 0.0 2.6 2 2 1 3 3 3 0 Myosin-binding striated muscle assembly central UBA_3 PF09288.5 EMC87100.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Surp PF01805.15 EMC87101.1 - 3e-19 68.4 0.5 6.4e-12 44.9 0.1 2.7 2 0 0 2 2 2 2 Surp module G-patch PF01585.18 EMC87101.1 - 2.5e-14 52.7 4.2 4.6e-14 51.9 2.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC87101.1 - 0.0033 17.2 2.6 0.0033 17.2 1.8 2.4 2 0 0 2 2 2 1 DExH-box splicing factor binding site CDC45 PF02724.9 EMC87101.1 - 0.83 7.6 6.4 1.2 7.0 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMC87101.1 - 5.6 4.7 19.1 0.36 8.6 9.7 1.5 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 EMC87101.1 - 6.6 5.0 20.9 0.25 9.7 10.3 1.6 2 0 0 2 2 2 0 Daxx Family WH1 PF00568.18 EMC87103.1 - 7.9e-37 125.3 0.2 1.5e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 WH1 domain CENP-B_N PF04218.8 EMC87103.1 - 0.0075 15.6 0.5 0.023 14.0 0.4 1.9 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Reo_sigmaC PF04582.7 EMC87103.1 - 0.61 9.2 7.4 1.2 8.2 1.3 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3461 PF11944.3 EMC87103.1 - 0.67 9.8 11.5 0.026 14.3 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) RTBV_P46 PF06216.6 EMC87103.1 - 0.91 8.2 6.9 4.1 6.1 0.8 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Flu_M1_C PF08289.6 EMC87103.1 - 1.1 9.3 4.7 0.56 10.2 0.5 2.5 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain Phage_GP20 PF06810.6 EMC87103.1 - 3.8 6.9 21.1 0.81 9.1 6.9 2.7 2 1 0 2 2 2 0 Phage minor structural protein GP20 Helicase_C PF00271.26 EMC87104.1 - 1.1e-23 82.8 0.0 2.2e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3978 PF13123.1 EMC87104.1 - 0.056 12.8 0.2 3.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3978) Coatomer_E PF04733.9 EMC87105.1 - 7.4e-73 245.2 1.3 8.2e-73 245.1 0.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EMC87105.1 - 2.8e-09 37.1 5.1 3.6e-05 24.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87105.1 - 2.4e-07 30.7 0.9 0.00098 19.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC87105.1 - 8.9e-06 25.5 0.4 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87105.1 - 1.2e-05 25.8 0.0 0.00082 19.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC87105.1 - 1.2e-05 24.8 4.6 0.00037 20.1 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMC87105.1 - 2.4e-05 23.8 0.1 0.00015 21.3 0.0 2.2 1 1 0 2 2 2 1 TPR repeat Apc3 PF12895.2 EMC87105.1 - 0.00033 20.7 5.4 0.023 14.8 0.1 2.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMC87105.1 - 0.0005 19.6 1.3 0.0015 18.1 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC87105.1 - 0.001 18.5 3.3 0.0026 17.2 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC87105.1 - 0.006 16.4 0.1 0.006 16.4 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 EMC87105.1 - 0.0077 16.1 1.4 3.5 7.8 0.0 3.3 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.1 EMC87105.1 - 0.035 14.0 2.7 19 5.3 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family DUF964 PF06133.6 EMC87105.1 - 0.039 13.9 0.4 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) CysG_dimeriser PF10414.4 EMC87105.1 - 0.091 12.2 0.8 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region TPR_6 PF13174.1 EMC87105.1 - 0.092 13.2 0.3 0.69 10.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87105.1 - 0.11 12.3 1.3 2.6 8.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat YfdX PF10938.3 EMC87105.1 - 0.13 11.9 0.9 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 YfdX protein TPR_17 PF13431.1 EMC87105.1 - 0.15 12.2 0.5 30 5.1 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMC87105.1 - 0.28 11.1 4.5 2.9 7.8 2.9 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.11 EMC87106.1 - 3.4e-20 72.4 26.9 1.5e-15 57.3 3.8 2.0 2 0 0 2 2 2 2 TLC domain TGF_beta PF00019.15 EMC87107.1 - 1.4e-42 144.1 0.2 2.6e-42 143.3 0.1 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC87107.1 - 6.7e-16 58.3 0.0 1.2e-15 57.4 0.0 1.4 2 0 0 2 2 2 1 TGF-beta propeptide TSP_C PF05735.7 EMC87109.1 - 6.1e-107 355.7 1.8 8.5e-107 355.2 1.3 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 EMC87109.1 - 3.2e-55 183.2 133.7 1.1e-11 43.9 7.7 9.4 7 2 1 8 8 8 8 Thrombospondin type 3 repeat EGF_CA PF07645.10 EMC87109.1 - 4.5e-18 64.9 44.7 4.8e-09 36.0 4.4 5.7 4 0 0 4 4 4 4 Calcium-binding EGF domain COMP PF11598.3 EMC87109.1 - 4.4e-15 55.4 1.6 1e-14 54.3 1.1 1.7 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein cEGF PF12662.2 EMC87109.1 - 2.5e-12 46.1 24.7 3.3e-06 26.6 2.2 6.1 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 EMC87109.1 - 1.6e-07 31.1 54.7 0.00023 21.0 3.2 6.1 6 0 0 6 6 6 4 EGF domain hEGF PF12661.2 EMC87109.1 - 0.0002 21.2 17.3 0.97 9.6 1.1 6.2 4 0 0 4 4 4 3 Human growth factor-like EGF EGF PF00008.22 EMC87109.1 - 0.0041 17.0 2.7 0.0041 17.0 1.8 5.5 4 0 0 4 4 4 3 EGF-like domain EGF_MSP1_1 PF12946.2 EMC87109.1 - 4.2 7.2 25.7 0.05 13.3 2.7 4.5 4 0 0 4 4 4 0 MSP1 EGF domain 1 BSMAP PF12280.3 EMC87110.1 - 2.1e-59 200.9 0.0 2.5e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein DNA_repr_REX1B PF14966.1 EMC87111.1 - 1.2e-06 28.8 0.0 1.3e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 DNA repair REX1-B KxDL PF10241.4 EMC87112.1 - 4.6e-27 93.7 1.8 6.4e-27 93.2 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein TPR_11 PF13414.1 EMC87113.1 - 5.4e-19 67.6 2.4 4.8e-10 38.9 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMC87113.1 - 2.7e-15 55.2 5.3 1e-05 24.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_C PF00254.23 EMC87113.1 - 3.7e-13 49.2 0.0 7.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.12 EMC87113.1 - 4.7e-13 47.9 3.3 4e-05 23.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87113.1 - 4.5e-11 43.1 0.1 2.2e-08 34.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC87113.1 - 1.6e-08 34.3 1.5 2.1e-06 27.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87113.1 - 2.6e-08 33.8 0.1 0.00071 19.9 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC87113.1 - 2.6e-08 33.6 2.2 0.00051 19.8 0.1 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EMC87113.1 - 1.1e-06 28.4 0.2 1.1e-05 25.1 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87113.1 - 1.7e-06 27.3 2.9 0.0005 19.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87113.1 - 2.5e-06 27.7 1.2 1.1e-05 25.6 0.5 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC87113.1 - 4.2e-06 26.1 0.7 0.0045 16.6 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87113.1 - 0.0001 22.2 0.7 0.0024 17.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC87113.1 - 0.00029 20.9 0.6 0.0019 18.3 0.1 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 EMC87113.1 - 0.0021 16.9 0.2 0.0028 16.4 0.2 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EMC87113.1 - 0.0067 16.8 0.9 0.34 11.4 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC87113.1 - 0.0073 16.2 7.3 3.1 7.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMC87113.1 - 0.073 13.1 0.2 0.28 11.3 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat NAD_binding_5 PF07994.7 EMC87114.1 - 4.2e-112 374.4 0.0 5e-112 374.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EMC87114.1 - 2.4e-47 159.3 0.1 3.8e-47 158.7 0.1 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase SSDP PF04503.8 EMC87115.1 - 3.6e-36 125.3 27.1 5.6e-36 124.7 18.8 1.3 1 0 0 1 1 1 1 Single-stranded DNA binding protein, SSDP TGF_beta PF00019.15 EMC87116.1 - 6.3e-29 100.3 2.1 7.4e-29 100.1 1.5 1.1 1 0 0 1 1 1 1 Transforming growth factor beta like domain Peptidase_C15 PF01470.12 EMC87117.1 - 1.1e-05 25.3 0.0 1.2e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase LSM PF01423.17 EMC87118.1 - 3.8e-15 55.2 0.0 5.6e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain PDEase_I PF00233.14 EMC87120.1 - 5.7e-104 347.0 6.4 7.8e-104 346.5 4.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DFP PF04127.10 EMC87120.1 - 0.1 12.2 0.3 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ras PF00071.17 EMC87121.1 - 1.3e-61 206.7 0.8 1.5e-61 206.4 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC87121.1 - 7.4e-19 68.4 0.0 1.1e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC87121.1 - 1.2e-14 53.9 0.1 1.5e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC87121.1 - 4.5e-06 25.9 0.1 5.8e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMC87121.1 - 5.1e-05 22.5 0.1 6.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC87121.1 - 0.00012 21.5 0.0 0.0005 19.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC87121.1 - 0.0034 17.3 0.0 0.0057 16.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC87121.1 - 0.0092 15.2 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_14 PF13173.1 EMC87121.1 - 0.016 15.0 0.1 0.039 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EMC87121.1 - 0.054 12.5 0.0 0.71 8.8 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_17 PF13207.1 EMC87121.1 - 0.081 13.7 0.1 1.7 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 EMC87121.1 - 0.084 11.5 0.6 5.1 5.6 0.0 2.8 2 1 0 3 3 3 0 G-protein alpha subunit Mpv17_PMP22 PF04117.7 EMC87122.1 - 1e-31 108.3 0.4 1.9e-31 107.4 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2818 PF10993.3 EMC87122.1 - 0.077 13.4 0.5 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) GILT PF03227.11 EMC87123.1 - 1.3e-24 86.0 0.1 1.9e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SH2 PF00017.19 EMC87124.1 - 1.6e-40 136.7 0.1 2e-19 69.1 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 EMC87124.1 - 8.9e-26 90.3 1.0 5.5e-25 87.7 0.0 2.5 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.23 EMC87124.1 - 5.5e-05 22.4 0.3 0.0068 15.7 0.0 3.3 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EMC87124.1 - 0.00075 19.0 0.3 0.0034 16.9 0.2 2.3 2 1 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC87124.1 - 0.0038 16.6 0.3 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain ATG11 PF10377.4 EMC87124.1 - 0.0057 16.5 0.6 0.0057 16.5 0.4 1.8 2 0 0 2 2 2 1 Autophagy-related protein 11 CENP-Q PF13094.1 EMC87124.1 - 0.11 12.4 15.6 0.19 11.7 10.3 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit fn3 PF00041.16 EMC87125.1 - 4.9e-10 39.4 0.1 1.7e-06 28.0 0.0 3.4 3 0 0 3 3 3 2 Fibronectin type III domain DUF2840 PF11000.3 EMC87125.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) Arrestin_N PF00339.24 EMC87126.1 - 2.6e-29 101.9 0.0 3.7e-28 98.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMC87126.1 - 7.4e-27 94.1 0.1 2.1e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 EMC87126.1 - 0.0077 15.0 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 LDB19 PF13002.2 EMC87126.1 - 0.078 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Arrestin_N terminal like PEX11 PF05648.9 EMC87127.1 - 1.3e-45 155.4 0.1 1.4e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Nodulin-like PF06813.8 EMC87127.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Nodulin-like PsbJ PF01788.12 EMC87127.1 - 6.5 6.3 7.0 0.53 9.8 1.0 2.0 2 0 0 2 2 2 0 PsbJ C1_1 PF00130.17 EMC87128.1 - 0.013 15.2 0.8 0.027 14.1 0.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LCD1 PF09798.4 EMC87128.1 - 2.3 6.0 6.4 3.2 5.6 4.4 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Pkinase_Tyr PF07714.12 EMC87129.1 - 2.7e-98 328.1 0.0 7.2e-98 326.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.19 EMC87129.1 - 1.1e-58 196.0 2.3 5.6e-29 100.3 0.1 2.4 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.20 EMC87129.1 - 4e-42 144.1 0.0 7.9e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 EMC87129.1 - 3.4e-36 124.1 43.1 8.4e-36 122.8 29.9 1.7 1 0 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.16 EMC87129.1 - 2.5e-21 75.6 2.0 4.1e-08 33.2 0.0 5.2 5 1 0 5 5 5 4 Fibronectin type III domain Kinase-like PF14531.1 EMC87129.1 - 8.5e-05 21.6 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like B2 PF11473.3 EMC87129.1 - 0.076 12.6 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 RNA binding protein B2 GF_recep_IV PF14843.1 EMC87129.1 - 8.6 5.9 44.6 0.65 9.6 19.7 3.4 1 1 1 2 2 2 0 Growth factor receptor domain IV Myosin_head PF00063.16 EMC87130.1 - 1.5e-188 628.0 3.8 1.5e-188 628.0 2.6 4.0 3 1 0 3 3 3 1 Myosin head (motor domain) RhoGAP PF00620.22 EMC87130.1 - 1.8e-47 160.7 0.2 6.2e-47 159.0 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain RA PF00788.18 EMC87130.1 - 2.6e-15 56.6 0.8 1.3e-14 54.3 0.0 2.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain IQ PF00612.22 EMC87130.1 - 2.6e-08 32.7 20.6 0.0018 17.7 0.4 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif C1_1 PF00130.17 EMC87130.1 - 0.00038 20.1 17.5 0.0008 19.0 12.1 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.1 EMC87130.1 - 0.0043 17.1 0.2 0.28 11.3 0.1 3.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC87130.1 - 0.21 11.3 0.1 0.51 10.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain A2M_comp PF07678.9 EMC87132.1 - 1.5e-80 269.9 0.5 2.2e-80 269.4 0.3 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 EMC87132.1 - 5e-34 117.0 1.1 9.5e-32 109.6 0.0 3.4 3 0 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 EMC87132.1 - 5.6e-29 99.5 0.1 5.6e-29 99.5 0.1 3.8 5 0 0 5 5 5 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 EMC87132.1 - 3.6e-28 97.5 0.0 1.2e-27 95.9 0.0 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor Methyltransf_FA PF12248.3 EMC87132.1 - 4.2e-27 94.1 0.1 1.3e-26 92.5 0.0 1.9 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase Thiol-ester_cl PF10569.4 EMC87132.1 - 5.7e-17 60.6 0.1 1.3e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region A2M_N PF01835.14 EMC87132.1 - 6.4e-16 58.4 0.0 2.4e-15 56.6 0.0 2.1 1 0 0 1 1 1 1 MG2 domain Prenyltrans_2 PF13249.1 EMC87132.1 - 1.9e-08 34.7 1.9 0.0072 16.7 0.0 3.3 1 1 2 3 3 3 3 Prenyltransferase-like Kazal_2 PF07648.10 EMC87132.1 - 3.1e-08 33.3 3.0 8.7e-08 31.9 2.1 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC87132.1 - 0.00091 19.1 10.2 0.001 19.0 5.9 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Prenyltrans_1 PF13243.1 EMC87132.1 - 0.0022 18.0 0.1 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 Prenyltransferase-like Rib PF08428.5 EMC87132.1 - 0.0081 15.9 0.2 0.083 12.6 0.0 2.5 2 0 0 2 2 2 1 Rib/alpha-like repeat 7tm_1 PF00001.16 EMC87133.1 - 2.8e-48 164.2 20.5 4.2e-48 163.7 14.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87133.1 - 1.2e-05 24.6 11.5 1.5e-05 24.2 8.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC87133.1 - 0.0033 16.5 12.5 0.0057 15.7 8.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 EMC87133.1 - 0.0039 16.3 10.5 0.006 15.7 2.3 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw TRIC PF05197.8 EMC87134.1 - 1.2e-92 308.7 6.8 1.5e-92 308.4 4.7 1.1 1 0 0 1 1 1 1 TRIC channel DUF788 PF05620.6 EMC87134.1 - 2.9 7.7 6.0 0.7 9.7 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF788) DUF2505 PF10698.4 EMC87135.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) TPT PF03151.11 EMC87136.1 - 6.3e-37 126.5 11.3 6.3e-37 126.5 7.8 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EMC87136.1 - 1.5e-09 37.9 15.5 1.8e-05 24.8 5.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EMC87136.1 - 1.6e-05 23.9 17.1 3.8e-05 22.7 11.9 1.6 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EMC87136.1 - 1.9e-05 24.8 11.2 0.0031 17.6 0.4 2.4 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EMC87136.1 - 0.0066 15.5 8.5 0.19 10.8 1.4 2.6 1 1 1 2 2 2 2 Nucleotide-sugar transporter DUF4131 PF13567.1 EMC87136.1 - 0.05 13.0 6.1 0.39 10.1 3.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) YwiC PF14256.1 EMC87136.1 - 0.48 10.5 6.1 0.088 12.8 0.4 2.2 1 1 1 2 2 2 0 YwiC-like protein DUF4614 PF15391.1 EMC87137.1 - 3.4e-07 30.2 0.2 3.4e-07 30.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) Calreticulin PF00262.13 EMC87138.1 - 6.6e-43 146.7 0.6 7.4e-43 146.5 0.4 1.0 1 0 0 1 1 1 1 Calreticulin family Kinetocho_Slk19 PF12709.2 EMC87138.1 - 0.068 13.2 0.8 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Central kinetochore-associated Adap_comp_sub PF00928.16 EMC87139.1 - 4.6e-92 307.8 0.3 5.9e-92 307.4 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMC87139.1 - 3.1e-05 23.7 0.8 5.3e-05 22.9 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SH3_5 PF08460.5 EMC87139.1 - 0.094 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain UPF0172 PF03665.8 EMC87140.1 - 0.0048 16.4 2.7 0.0056 16.2 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Ribosomal_L17 PF01196.14 EMC87140.1 - 0.21 12.1 3.8 0.26 11.8 2.6 1.1 1 0 0 1 1 1 0 Ribosomal protein L17 DUF1754 PF08555.5 EMC87140.1 - 0.27 11.8 19.5 0.29 11.7 10.9 2.5 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Wx5_PLAF3D7 PF09688.5 EMC87140.1 - 0.32 10.9 4.7 0.35 10.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) DDE_Tnp_IS240 PF13610.1 EMC87140.1 - 0.59 10.1 5.1 0.69 9.8 3.5 1.1 1 0 0 1 1 1 0 DDE domain UPF0242 PF06785.6 EMC87140.1 - 1.2 7.7 5.5 1.4 7.5 3.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) V_ATPase_I PF01496.14 EMC87140.1 - 1.8 6.3 4.7 1.9 6.2 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAUB PF08164.7 EMC87140.1 - 1.8 8.6 8.2 2.6 8.2 5.7 1.3 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Ebp2 PF05890.7 EMC87140.1 - 5 6.3 16.9 7.9 5.7 11.7 1.3 1 1 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 HSP70 PF00012.15 EMC87140.1 - 5.2 4.8 8.5 5.6 4.7 5.9 1.0 1 0 0 1 1 1 0 Hsp70 protein EF-hand_7 PF13499.1 EMC87141.1 - 9.1e-15 54.5 5.7 9.5e-12 44.8 1.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC87141.1 - 5e-12 44.2 9.5 2e-05 23.5 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC87141.1 - 5.1e-09 35.2 9.6 0.0045 16.7 0.2 4.2 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EMC87141.1 - 6e-05 22.1 6.3 0.0012 18.0 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EMC87141.1 - 0.00011 21.6 10.8 0.00058 19.4 0.4 3.2 2 1 2 4 4 4 3 EF-hand domain pair AF0941-like PF14591.1 EMC87141.1 - 0.0026 17.8 0.1 0.0095 15.9 0.1 1.8 2 1 0 2 2 2 1 AF0941-like VCBS PF13517.1 EMC87141.1 - 0.068 13.5 0.1 17 5.8 0.0 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SPARC_Ca_bdg PF10591.4 EMC87141.1 - 0.069 13.1 1.0 0.17 11.9 0.7 1.8 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Mob1_phocein PF03637.12 EMC87142.1 - 6.2e-79 263.7 0.4 7.3e-79 263.4 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family PHR PF08005.7 EMC87145.1 - 3.6e-52 176.5 0.6 5.4e-52 175.9 0.4 1.3 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 EMC87145.1 - 8.5e-22 77.2 0.3 6.6e-20 71.1 0.0 2.9 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.10 EMC87145.1 - 7.5e-10 38.5 0.8 2.2e-08 33.8 0.1 3.0 1 1 1 2 2 2 1 BTB And C-terminal Kelch zf-C4 PF00105.13 EMC87146.1 - 4.5e-33 113.3 13.6 1.1e-32 112.0 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 EMC87146.1 - 3e-32 111.4 2.6 6e-32 110.4 1.8 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-A20 PF01754.11 EMC87147.1 - 3.2e-13 48.9 6.1 7.4e-13 47.8 4.2 1.7 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 EMC87147.1 - 9.9e-12 44.5 5.7 9.9e-12 44.5 3.9 2.5 3 0 0 3 3 3 1 AN1-like Zinc finger Abhydrolase_5 PF12695.2 EMC87148.1 - 2e-17 63.2 0.0 3.9e-16 59.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC87148.1 - 2.9e-08 33.8 0.0 0.00055 19.8 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC87148.1 - 0.0047 16.4 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC87148.1 - 0.0057 15.9 0.0 0.0078 15.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.7 EMC87148.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 EMC87148.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 EMC87148.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMC87148.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CUT PF02376.10 EMC87150.1 - 5.8e-32 109.3 0.1 1.2e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 CUT domain Homeobox PF00046.24 EMC87150.1 - 1e-09 37.8 1.3 1.9e-09 36.9 0.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC87150.1 - 0.0057 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain HLH PF00010.21 EMC87151.1 - 4.2e-10 39.1 1.0 7.9e-10 38.2 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4349 PF14257.1 EMC87151.1 - 0.076 12.2 0.6 0.12 11.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) UCR_6-4kD PF08997.5 EMC87152.1 - 5.2e-18 64.5 1.3 5.8e-18 64.3 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.4 EMC87152.1 - 0.00064 19.3 1.6 0.0035 16.9 1.1 1.8 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MBD_C PF14048.1 EMC87153.1 - 1.1e-26 93.2 0.2 2.5e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.14 EMC87153.1 - 1.7e-11 43.4 0.2 7.7e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Methyl-CpG binding domain DUF1107 PF06526.7 EMC87153.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1107) KH_1 PF00013.24 EMC87154.1 - 2e-19 69.0 3.4 1.1e-13 50.6 0.2 2.7 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 EMC87154.1 - 3.1e-10 39.4 0.1 1e-06 28.2 0.0 3.0 3 0 0 3 3 3 2 KH domain zf-C3HC4_3 PF13920.1 EMC87154.1 - 7.8e-10 38.2 10.9 1.2e-09 37.6 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC87154.1 - 7.4e-07 29.0 11.7 1.3e-06 28.3 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC87154.1 - 0.00071 19.1 10.9 0.0012 18.4 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87154.1 - 0.0043 16.7 11.0 0.0081 15.8 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain KH_2 PF07650.12 EMC87154.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 KH domain zf-RING_6 PF14835.1 EMC87154.1 - 1.3 8.8 6.3 3.1 7.6 4.4 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EMC87154.1 - 1.8 8.5 10.3 5 7.0 7.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC87154.1 - 3.1 7.4 9.2 6.7 6.3 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain 7tm_4 PF13853.1 EMC87155.1 - 6.8e-50 168.6 7.2 7.6e-50 168.4 5.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC87155.1 - 3.5e-06 26.3 4.8 4.1e-06 26.1 3.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Herpes_UL45 PF05473.7 EMC87156.1 - 0.049 13.0 0.6 0.053 12.9 0.4 1.1 1 0 0 1 1 1 0 UL45 protein PSP1 PF04468.7 EMC87158.1 - 0.019 14.9 0.3 0.053 13.5 0.1 1.8 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Ten_N PF06484.7 EMC87159.1 - 5.5e-29 101.4 3.3 6.4e-29 101.1 2.3 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region dCMP_cyt_deam_1 PF00383.17 EMC87160.1 - 2.8e-28 97.5 0.1 4.6e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1293 PF06950.6 EMC87160.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) Rap_GAP PF02145.10 EMC87162.1 - 3.8e-40 137.2 0.0 2.7e-38 131.2 0.0 2.5 1 1 0 1 1 1 1 Rap/ran-GAP MA3 PF02847.12 EMC87165.1 - 5.9e-53 177.3 0.3 6e-27 93.5 0.2 2.1 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.10 EMC87165.1 - 0.015 15.7 0.1 0.015 15.7 0.0 1.9 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family LRR_4 PF12799.2 EMC87166.1 - 1.8e-64 212.5 84.5 1.4e-09 37.3 2.3 11.5 5 3 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC87166.1 - 2.6e-55 184.0 113.7 1.4e-10 40.7 3.7 9.6 3 2 9 12 12 12 12 Leucine rich repeat LRR_1 PF00560.28 EMC87166.1 - 4.8e-41 132.4 63.8 0.17 12.0 0.0 19.6 20 0 0 20 20 20 16 Leucine Rich Repeat LRR_7 PF13504.1 EMC87166.1 - 4e-21 71.3 72.6 0.62 10.4 0.1 18.8 19 0 0 19 19 19 7 Leucine rich repeat LRR_9 PF14580.1 EMC87166.1 - 0.0014 18.2 27.3 0.23 10.9 2.1 5.0 1 1 6 7 7 7 5 Leucine-rich repeat LRR_6 PF13516.1 EMC87166.1 - 0.035 14.1 70.1 13 6.2 0.1 16.7 14 5 4 18 18 18 0 Leucine Rich repeat SUFU_C PF12470.3 EMC87166.1 - 1.3 8.5 3.5 0.84 9.1 0.3 2.2 3 0 0 3 3 3 0 Suppressor of Fused Gli/Ci N terminal binding domain 7tm_1 PF00001.16 EMC87167.1 - 7e-83 277.6 0.0 9.5e-83 277.2 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87167.1 - 1.7e-10 40.4 12.1 1.3e-06 27.7 3.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC87167.1 - 6.7e-06 25.4 16.0 1.3e-05 24.4 5.8 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx T2SM PF04612.7 EMC87167.1 - 0.043 13.6 0.1 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Herpes_US9 PF06072.6 EMC87167.1 - 0.26 11.1 1.6 2.4 8.0 0.1 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Acyltransferase PF01553.16 EMC87168.1 - 9.6e-22 76.8 0.0 2.7e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 Acyltransferase Zona_pellucida PF00100.18 EMC87169.1 - 1.7e-40 139.1 7.6 2e-40 138.9 5.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain AMP-binding PF00501.23 EMC87170.1 - 2e-102 342.7 0.0 2.5e-102 342.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme zf-DHHC PF01529.15 EMC87171.1 - 3.1e-36 124.3 6.1 4.7e-36 123.7 4.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase SH3_2 PF07653.12 EMC87171.1 - 5.2e-09 35.4 0.4 1.7e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EMC87171.1 - 0.0026 17.2 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain V-SNARE PF05008.10 EMC87172.1 - 6.7e-25 87.0 0.2 6.7e-25 87.0 0.1 2.4 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EMC87172.1 - 9.7e-22 76.8 6.9 1.2e-20 73.3 4.2 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 EMC87172.1 - 0.0023 17.6 0.2 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 Laminin Domain II DUF1664 PF07889.7 EMC87172.1 - 0.018 14.8 0.9 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.6 EMC87172.1 - 0.032 14.2 5.6 0.41 10.6 0.3 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Peptidase_S46 PF10459.4 EMC87172.1 - 0.043 12.2 4.5 0.052 11.9 3.1 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF2730 PF10805.3 EMC87172.1 - 0.15 11.7 1.3 0.76 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Sec20 PF03908.8 EMC87172.1 - 0.18 11.5 0.7 1 9.1 0.1 2.2 2 1 0 2 2 2 0 Sec20 TMPIT PF07851.8 EMC87172.1 - 0.54 9.2 5.0 4 6.4 0.1 2.1 1 1 0 2 2 2 0 TMPIT-like protein Pox_A_type_inc PF04508.7 EMC87172.1 - 0.83 9.6 0.0 0.83 9.6 0.0 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 EMC87172.1 - 2.2 8.2 5.6 0.57 10.1 0.6 2.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Metal_resist PF13801.1 EMC87172.1 - 5.9 6.8 8.5 6.1 6.8 0.6 2.7 2 2 0 2 2 2 0 Heavy-metal resistance Mnd1 PF03962.10 EMC87172.1 - 7.1 6.2 10.0 80 2.8 6.9 2.1 1 1 0 1 1 1 0 Mnd1 family THOC7 PF05615.8 EMC87172.1 - 8.5 6.6 12.5 1.4 9.1 1.5 2.4 1 1 0 2 2 2 0 Tho complex subunit 7 CTNNB1_binding PF08347.6 EMC87173.1 - 1.7e-36 126.4 9.9 1.7e-36 126.4 6.9 2.8 2 1 1 3 3 3 1 N-terminal CTNNB1 binding HMG_box PF00505.14 EMC87173.1 - 2.4e-22 78.9 1.0 5.1e-22 77.9 0.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC87173.1 - 5e-08 33.2 1.5 1.1e-07 32.1 1.1 1.5 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EMC87173.1 - 0.058 12.7 0.1 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 7tm_1 PF00001.16 EMC87174.1 - 4.1e-50 170.3 20.5 5e-50 170.0 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87174.1 - 8.5e-17 61.1 17.5 1.1e-16 60.8 12.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC87174.1 - 0.00017 20.7 19.3 0.00027 20.1 13.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx RhoGAP PF00620.22 EMC87175.1 - 6.7e-32 110.2 0.1 1.4e-31 109.1 0.1 1.5 1 1 0 1 1 1 1 RhoGAP domain RhoGAP PF00620.22 EMC87176.1 - 0.004 16.7 0.1 0.0074 15.9 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Gal-bind_lectin PF00337.17 EMC87177.1 - 5.2e-23 80.8 0.0 5.7e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin SERTA PF06031.8 EMC87178.1 - 6.5e-17 60.5 1.3 1e-16 59.9 0.9 1.3 1 0 0 1 1 1 1 SERTA motif SDF PF00375.13 EMC87179.1 - 2.4e-101 339.3 17.9 2.7e-101 339.1 12.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Ras PF00071.17 EMC87180.1 - 1.4e-67 226.1 1.1 1.6e-67 225.9 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC87180.1 - 1.8e-23 83.2 0.0 2.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC87180.1 - 1.6e-17 63.3 0.2 1.9e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC87180.1 - 4.2e-07 29.3 0.1 4.8e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC87180.1 - 2.6e-06 27.0 0.2 5.8e-06 25.8 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC87180.1 - 7.5e-06 25.8 0.1 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMC87180.1 - 1.2e-05 24.6 0.1 1.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EMC87180.1 - 0.00051 20.2 0.0 0.076 13.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC87180.1 - 0.00061 19.9 0.0 0.00095 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EMC87180.1 - 0.0022 17.3 0.0 0.012 14.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EMC87180.1 - 0.0059 15.7 0.1 0.021 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EMC87180.1 - 0.017 14.6 0.1 0.86 9.0 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EMC87180.1 - 0.033 14.1 0.1 0.092 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EMC87180.1 - 0.046 14.0 0.0 0.065 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EMC87180.1 - 0.049 13.3 0.0 0.068 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EMC87180.1 - 0.05 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EMC87180.1 - 0.069 12.1 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 EMC87180.1 - 1.1 7.9 5.9 5.8 5.4 0.7 2.8 1 1 1 2 2 2 0 G-protein alpha subunit Actin PF00022.14 EMC87181.1 - 4e-117 390.9 0.0 4.6e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 Actin Sprouty PF05210.8 EMC87182.1 - 1.2e-39 134.6 27.4 1.2e-39 134.6 19.0 2.0 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.18 EMC87182.1 - 1.8e-10 40.4 0.0 3.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 WH1 domain Homeobox_KN PF05920.6 EMC87184.1 - 2.1e-16 59.3 0.1 3.2e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC87184.1 - 1.1e-07 31.3 0.1 1.6e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Homeobox domain ETAA1 PF15350.1 EMC87185.1 - 1.8e-132 443.1 30.9 3.2e-97 326.5 2.7 2.0 1 1 0 2 2 2 2 Ewing's tumour-associated antigen 1 homologue DUF1065 PF06358.6 EMC87185.1 - 0.18 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) Sas10_Utp3 PF04000.10 EMC87186.1 - 6.6e-19 67.8 0.6 1e-18 67.3 0.4 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SF-assemblin PF06705.6 EMC87186.1 - 0.041 13.0 0.2 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Herpes_V23 PF01802.12 EMC87186.1 - 0.045 12.7 0.1 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF932 PF06067.6 EMC87186.1 - 0.078 12.2 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Spc7 PF08317.6 EMC87186.1 - 0.09 11.4 2.0 0.28 9.7 1.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.27 EMC87187.1 - 4.5e-17 61.2 1.9 4.6e-06 26.3 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMC87187.1 - 0.0072 16.0 0.1 0.14 11.9 0.0 2.6 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EMC87187.1 - 0.029 14.0 0.1 12 5.5 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A KH_1 PF00013.24 EMC87188.1 - 3.4e-07 29.7 1.3 8.3e-07 28.5 0.9 1.6 1 0 0 1 1 1 1 KH domain EF-hand_1 PF00036.27 EMC87189.1 - 3.3e-28 94.8 13.3 1.2e-06 27.4 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 EMC87189.1 - 2.5e-27 94.8 2.5 6.5e-14 51.8 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC87189.1 - 2.9e-22 76.4 6.6 9.1e-06 25.1 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC87189.1 - 9.7e-22 75.2 10.8 2.9e-05 23.1 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EMC87189.1 - 1.5e-20 72.5 7.5 0.00012 21.5 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC87189.1 - 3.2e-08 33.5 0.1 0.00064 19.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC87189.1 - 1.2e-07 31.3 4.7 0.0032 17.1 0.2 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMC87189.1 - 0.00035 20.4 0.1 0.035 14.0 0.0 2.6 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.8 EMC87189.1 - 0.056 12.9 0.5 3.6 7.1 0.0 2.3 1 1 1 2 2 2 0 Caleosin related protein OST-HTH PF12872.2 EMC87189.1 - 0.12 12.2 0.1 1.9 8.3 0.1 2.7 3 1 0 3 3 3 0 OST-HTH/LOTUS domain RhoGAP PF00620.22 EMC87190.1 - 0.0029 17.2 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.11 EMC87191.1 - 2.8e-43 147.9 28.4 9e-36 123.2 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC87191.1 - 2.1e-05 24.1 11.6 0.18 11.6 3.0 4.4 3 1 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.19 EMC87191.1 - 0.00048 18.8 10.9 0.00048 18.8 7.5 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter DUF2140 PF09911.4 EMC87191.1 - 0.058 12.5 0.0 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) MFS_3 PF05977.8 EMC87191.1 - 0.58 8.2 4.5 0.11 10.5 0.3 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector TAFA PF12020.3 EMC87192.1 - 6.3e-40 135.2 8.6 8.1e-40 134.8 5.9 1.1 1 0 0 1 1 1 1 TAFA family UCH PF00443.24 EMC87193.1 - 6.6e-93 310.6 0.0 1.4e-92 309.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.1 EMC87193.1 - 6.2e-38 128.3 0.1 1.3e-37 127.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain UCH_1 PF13423.1 EMC87193.1 - 1.7e-22 80.2 0.0 6.3e-13 48.8 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EMC87193.1 - 7.2e-21 74.4 1.2 7.2e-21 74.4 0.8 2.8 2 0 0 2 2 2 1 DUSP domain USP7_C2 PF14533.1 EMC87193.1 - 1.2e-08 34.6 0.1 1.8e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal CW_binding_1 PF01473.15 EMC87193.1 - 0.29 11.3 8.0 0.27 11.4 3.3 2.7 2 0 0 2 2 2 0 Putative cell wall binding repeat Sec7_N PF12783.2 EMC87194.1 - 3.6e-22 78.5 2.6 3.2e-13 49.4 0.4 3.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMC87194.1 - 1.1e-18 66.4 0.4 7.7e-17 60.5 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.17 EMC87194.1 - 0.0012 18.7 0.5 14 6.0 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Cullin PF00888.17 EMC87195.1 - 4.9e-14 51.7 0.1 5.4e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Cullin family Exo70 PF03081.10 EMC87195.1 - 0.031 13.0 0.1 0.031 13.0 0.1 1.3 2 0 0 2 2 2 0 Exo70 exocyst complex subunit PCI PF01399.22 EMC87196.1 - 2.3e-18 66.4 0.1 2.3e-18 66.4 0.1 2.7 2 0 0 2 2 2 1 PCI domain Gag_p30 PF02093.11 EMC87197.1 - 1.1e-23 83.5 0.1 1.3e-23 83.3 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein TipAS PF07739.8 EMC87197.1 - 0.021 15.1 0.1 0.56 10.5 0.0 2.5 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain PPP4R2 PF09184.6 EMC87197.1 - 0.098 12.1 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 PPP4R2 C1-set PF07654.10 EMC87198.1 - 6.6e-05 22.8 0.2 0.00013 21.9 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin C1-set domain Trypsin PF00089.21 EMC87199.1 - 3.6e-58 196.7 0.2 4.1e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMC87199.1 - 0.0032 17.4 0.0 0.0063 16.5 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 EMC87199.1 - 0.012 14.9 0.1 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Ion_trans_N PF08412.5 EMC87199.1 - 0.048 12.9 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ion transport protein N-terminal VIT PF08487.5 EMC87200.1 - 2.3e-12 46.6 0.0 3.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.1 EMC87200.1 - 2.5e-12 46.7 0.0 9.4e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 EMC87200.1 - 5.6e-07 28.9 0.5 9.7e-07 28.1 0.3 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain 7tm_4 PF13853.1 EMC87201.1 - 7.8e-38 129.5 18.4 7.8e-38 129.5 12.7 2.0 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC87201.1 - 3.7e-21 75.4 26.1 5.3e-21 74.9 18.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC87202.1 - 1.2e-49 167.8 15.4 1.2e-49 167.8 10.7 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC87202.1 - 2.8e-32 111.8 22.4 3.8e-32 111.4 15.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87202.1 - 5.7e-07 28.9 24.2 1.4e-06 27.6 16.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Trypsin PF00089.21 EMC87203.1 - 3.6e-58 196.7 0.2 4.1e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMC87203.1 - 0.0032 17.4 0.0 0.0063 16.5 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 EMC87203.1 - 0.012 14.9 0.1 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Ion_trans_N PF08412.5 EMC87203.1 - 0.048 12.9 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ion transport protein N-terminal DUF1731 PF08338.6 EMC87204.1 - 1.2e-17 63.0 0.0 2.4e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.16 EMC87204.1 - 0.0048 16.3 0.0 0.019 14.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 7tm_4 PF13853.1 EMC87205.1 - 1.8e-43 147.7 17.8 1.8e-43 147.7 12.3 2.6 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC87205.1 - 6.4e-29 100.8 22.3 7.9e-29 100.5 15.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87205.1 - 1.5e-05 24.2 26.6 3.1e-05 23.2 18.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC87206.1 - 1.7e-40 138.1 20.8 1.7e-40 138.1 14.4 2.6 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC87206.1 - 4.1e-29 101.5 27.8 5.5e-29 101.0 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87206.1 - 0.007 15.5 29.9 0.01 15.0 20.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF760 PF05542.6 EMC87206.1 - 0.15 12.2 1.2 21 5.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF760) 7TM_GPCR_Srx PF10328.4 EMC87206.1 - 1.2 8.2 32.1 2 7.4 22.2 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 EMC87208.1 - 3.5e-42 143.6 19.1 3.5e-42 143.6 13.3 2.6 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC87208.1 - 6.7e-29 100.8 30.6 6.7e-29 100.8 21.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC87209.1 - 5.7e-45 152.6 14.6 5.7e-45 152.6 10.1 2.7 2 1 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC87209.1 - 3.2e-33 114.9 22.3 4.3e-33 114.5 15.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sterol_MT_C PF08498.5 EMC87209.1 - 0.087 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal 7TM_GPCR_Srsx PF10320.4 EMC87209.1 - 4.9 6.2 28.4 56 2.7 19.2 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx BRICHOS PF04089.9 EMC87214.1 - 4.2e-11 42.5 0.0 7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 BRICHOS domain BRICHOS PF04089.9 EMC87215.1 - 1.3e-17 63.4 0.0 1.5e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 BRICHOS domain TGF_beta PF00019.15 EMC87216.1 - 1.2e-36 125.1 0.6 2.2e-36 124.3 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC87216.1 - 3.3e-32 111.6 0.1 5e-32 111.1 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide RhoGAP PF00620.22 EMC87217.1 - 8.7e-44 148.7 0.7 1.4e-42 144.8 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EMC87217.1 - 1.5e-17 63.7 0.0 3.8e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC87217.1 - 1.2e-05 25.5 2.7 1.2e-05 25.5 1.9 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EMC87217.1 - 1.4e-05 25.0 0.6 0.00033 20.6 0.4 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Tropomyosin_1 PF12718.2 EMC87217.1 - 0.008 16.0 20.4 0.013 15.3 14.1 1.3 1 0 0 1 1 1 1 Tropomyosin like Nsp1_C PF05064.8 EMC87217.1 - 0.0091 15.6 12.8 0.0096 15.5 7.8 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.4 EMC87217.1 - 0.024 14.4 20.1 0.048 13.5 14.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PH_9 PF15410.1 EMC87217.1 - 0.032 14.3 2.1 0.38 10.9 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain LUC7 PF03194.10 EMC87217.1 - 0.24 10.8 11.5 0.37 10.2 8.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus ADIP PF11559.3 EMC87217.1 - 0.4 10.5 14.4 1 9.2 10.0 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EMC87217.1 - 2.9 7.7 22.5 0.65 9.8 7.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Microtub_assoc PF07989.6 EMC87217.1 - 4.2 7.2 17.3 2.5 7.9 9.4 2.3 2 0 0 2 2 2 0 Microtubule associated APG6 PF04111.7 EMC87217.1 - 4.3 6.2 17.4 6.6 5.6 12.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EMC87217.1 - 6.5 6.3 16.8 1.2 8.7 8.8 1.8 2 0 0 2 2 2 0 IncA protein CTP_transf_1 PF01148.15 EMC87218.1 - 1e-89 300.6 25.5 1.2e-89 300.3 17.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF373 PF04123.8 EMC87218.1 - 7 5.5 8.2 2.9 6.8 3.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) PCNA_C PF02747.10 EMC87219.1 - 4.6e-68 227.0 0.0 7.5e-68 226.3 0.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EMC87219.1 - 2.9e-55 185.1 0.1 1.1e-54 183.3 0.1 1.9 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 EMC87219.1 - 2.1e-06 26.7 0.0 0.00047 19.0 0.0 2.1 1 1 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EMC87219.1 - 7.4e-05 21.9 0.0 0.00014 21.0 0.0 1.4 1 1 0 1 1 1 1 Rad9 DUF872 PF05915.7 EMC87220.1 - 9.5e-28 96.3 0.9 1.2e-27 96.0 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) UbiA PF01040.13 EMC87220.1 - 0.013 14.7 0.9 0.015 14.5 0.6 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF308 PF03729.8 EMC87220.1 - 0.033 14.1 11.0 0.05 13.5 6.9 1.7 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Pox_A14 PF05767.7 EMC87220.1 - 0.07 13.1 0.9 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF973 PF06157.6 EMC87220.1 - 0.23 10.4 4.9 0.3 10.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1700 PF08006.6 EMC87220.1 - 0.23 10.7 2.9 0.3 10.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Neurensin PF14927.1 EMC87220.1 - 0.3 10.4 3.4 3.4 7.0 2.3 2.0 1 1 0 1 1 1 0 Neurensin RseC_MucC PF04246.7 EMC87220.1 - 0.92 9.0 4.3 1.2 8.6 3.0 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SdpI PF13630.1 EMC87220.1 - 2.3 8.0 7.9 3.3 7.4 5.5 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Tetraspannin PF00335.15 EMC87220.1 - 2.7 7.1 5.0 3.5 6.8 3.5 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2627 PF11118.3 EMC87220.1 - 5.2 7.2 7.8 1.1 9.4 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Xan_ur_permease PF00860.15 EMC87221.1 - 1.1e-90 303.9 21.1 1.6e-90 303.4 14.6 1.2 1 0 0 1 1 1 1 Permease family Prion PF00377.13 EMC87224.1 - 9.1e-42 141.4 0.0 1.3e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Prion/Doppel alpha-helical domain SNARE_assoc PF09335.6 EMC87224.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Prominin PF05478.6 EMC87225.1 - 7.4e-131 437.2 0.0 9e-131 436.9 0.0 1.0 1 0 0 1 1 1 1 Prominin DSPc PF00782.15 EMC87226.1 - 1.3e-15 57.1 0.0 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC87226.1 - 0.0028 17.0 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC87226.1 - 0.0037 17.5 0.3 0.0071 16.6 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPn PF14671.1 EMC87226.1 - 0.0082 16.1 0.0 0.031 14.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half USP8_dimer PF08969.6 EMC87227.1 - 1.8e-20 72.9 0.4 1.8e-20 72.9 0.3 1.8 1 1 1 2 2 2 1 USP8 dimerisation domain JAB PF01398.16 EMC87227.1 - 1.9e-19 69.4 0.1 1.9e-19 69.4 0.1 2.0 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMC87227.1 - 9.3e-08 31.5 0.0 9.3e-08 31.5 0.0 2.3 3 0 0 3 3 3 1 Prokaryotic homologs of the JAB domain DUF3959 PF13105.1 EMC87227.1 - 1.8 7.8 6.8 2.8 7.1 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) MRP-S27 PF10037.4 EMC87227.1 - 3.3 6.5 12.6 4.5 6.0 8.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Actin PF00022.14 EMC87228.1 - 7.6e-127 422.9 0.0 8.6e-127 422.8 0.0 1.0 1 0 0 1 1 1 1 Actin dNK PF01712.14 EMC87229.1 - 1.1e-36 125.9 0.0 1.4e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 EMC87229.1 - 0.0002 21.6 0.2 0.033 14.4 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EMC87229.1 - 0.0021 17.9 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 EMC87229.1 - 0.066 12.5 0.0 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase BolA PF01722.13 EMC87230.1 - 1e-15 57.4 0.0 1.2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Glucokinase PF02685.11 EMC87230.1 - 0.012 14.3 0.1 0.014 14.2 0.0 1.0 1 0 0 1 1 1 0 Glucokinase THF_DHG_CYH PF00763.18 EMC87231.1 - 1.5e-34 118.4 0.1 1.7e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EMC87231.1 - 0.00021 20.4 0.0 0.00043 19.3 0.0 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HCO3_cotransp PF00955.16 EMC87232.1 - 3.5e-237 788.0 9.4 4.3e-237 787.8 6.5 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 EMC87232.1 - 1e-61 208.6 0.0 1.7e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Xan_ur_permease PF00860.15 EMC87232.1 - 0.48 8.8 15.7 0.041 12.3 0.7 2.7 3 0 0 3 3 3 0 Permease family Tetraspannin PF00335.15 EMC87233.1 - 4.7e-34 117.5 10.3 6e-34 117.2 7.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF996 PF06195.8 EMC87233.1 - 0.08 12.9 6.7 0.04 13.8 3.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF805 PF05656.9 EMC87233.1 - 6.9 6.5 7.7 6.1 6.6 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF4064 PF13273.1 EMC87233.1 - 8.9 6.4 13.2 7.6 6.7 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) 7tm_1 PF00001.16 EMC87234.1 - 7.5e-35 120.3 11.4 9.4e-35 119.9 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87234.1 - 0.0011 18.1 3.9 0.0014 17.8 2.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1673 PF07895.6 EMC87234.1 - 0.066 12.7 3.2 0.19 11.2 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF1282 PF06930.7 EMC87234.1 - 7 6.2 10.9 0.18 11.4 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Cnd2 PF05786.9 EMC87235.1 - 3.3e-17 62.2 0.1 3.4e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Cnd2 PF05786.9 EMC87236.1 - 2e-91 307.6 0.1 2.3e-91 307.4 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Pkinase PF00069.20 EMC87237.1 - 2e-65 220.5 0.0 6.5e-65 218.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87237.1 - 2e-43 148.3 1.8 2.8e-43 147.8 0.0 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase PKK PF12474.3 EMC87237.1 - 5.8e-17 61.7 83.9 2.8e-16 59.5 24.5 4.7 3 2 2 5 5 5 3 Polo kinase kinase ARID PF01388.16 EMC87238.1 - 9.7e-17 60.6 0.0 1e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Abhydrolase_5 PF12695.2 EMC87239.1 - 8e-08 32.1 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC87239.1 - 0.011 15.6 0.5 1.8 8.3 0.2 2.7 2 1 1 3 3 3 0 Alpha/beta hydrolase family PRY PF13765.1 EMC87242.1 - 7.2e-19 67.0 0.1 8.9e-19 66.7 0.0 1.1 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 EMC87242.1 - 0.0019 18.3 0.7 0.003 17.6 0.3 1.5 2 0 0 2 2 2 1 SPRY domain DUF3279 PF11682.3 EMC87242.1 - 0.083 12.4 0.4 0.083 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) 7tm_4 PF13853.1 EMC87244.1 - 3.2e-26 91.8 0.5 3.7e-26 91.6 0.3 1.0 1 0 0 1 1 1 1 Olfactory receptor DUF1242 PF06842.7 EMC87244.1 - 0.027 13.9 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) GCOM2 PF15328.1 EMC87246.1 - 4.2e-08 33.2 4.0 4.9e-08 32.9 2.7 1.1 1 0 0 1 1 1 1 Putative GRINL1B complex locus protein 2 bZIP_1 PF00170.16 EMC87246.1 - 0.002 18.0 18.4 0.0079 16.1 0.6 3.5 3 1 0 3 3 3 2 bZIP transcription factor Cast PF10174.4 EMC87246.1 - 0.0028 15.7 13.1 0.0028 15.7 9.1 1.5 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 EMC87246.1 - 0.011 14.8 0.5 0.013 14.7 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SlyX PF04102.7 EMC87246.1 - 0.012 15.9 17.8 0.16 12.3 4.3 3.2 2 1 1 3 3 3 0 SlyX Prominin PF05478.6 EMC87246.1 - 0.024 12.2 2.7 0.025 12.1 1.8 1.1 1 0 0 1 1 1 0 Prominin Herpes_env PF01673.13 EMC87246.1 - 0.031 12.8 0.7 0.092 11.2 0.0 1.8 1 1 1 2 2 2 0 Herpesvirus putative major envelope glycoprotein Tropomyosin_1 PF12718.2 EMC87246.1 - 0.031 14.1 17.9 0.061 13.1 12.4 1.5 1 1 0 1 1 1 0 Tropomyosin like IDO PF01231.13 EMC87246.1 - 0.033 12.6 0.5 0.052 11.9 0.3 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF2265 PF10023.4 EMC87246.1 - 0.053 12.6 3.0 0.063 12.4 2.1 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) HAUS5 PF14817.1 EMC87246.1 - 0.056 11.9 13.6 0.073 11.5 9.2 1.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Gp58 PF07902.6 EMC87246.1 - 0.058 11.6 2.3 0.064 11.4 1.6 1.0 1 0 0 1 1 1 0 gp58-like protein NYD-SP28 PF14772.1 EMC87246.1 - 0.06 13.4 12.1 4 7.5 8.1 2.4 1 1 0 1 1 1 0 Sperm tail VirC1 PF07015.6 EMC87246.1 - 0.073 12.1 0.3 0.093 11.7 0.2 1.1 1 0 0 1 1 1 0 VirC1 protein bZIP_2 PF07716.10 EMC87246.1 - 0.079 12.8 1.1 0.079 12.8 0.7 3.6 3 2 0 3 3 2 0 Basic region leucine zipper RasGAP_C PF03836.10 EMC87246.1 - 0.1 12.3 8.3 0.21 11.2 2.5 2.2 1 1 1 2 2 2 0 RasGAP C-terminus ADIP PF11559.3 EMC87246.1 - 0.1 12.5 17.5 0.29 11.0 7.8 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EMC87246.1 - 0.11 11.0 12.8 0.15 10.6 8.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LMBR1 PF04791.11 EMC87246.1 - 0.13 10.8 2.3 0.13 10.7 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein COG2 PF06148.6 EMC87246.1 - 0.14 12.0 9.8 0.21 11.4 5.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.4 EMC87246.1 - 0.15 12.0 17.0 1 9.3 8.1 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4200 PF13863.1 EMC87246.1 - 0.15 12.0 19.5 0.05 13.5 7.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fmp27_WPPW PF10359.4 EMC87246.1 - 0.16 10.3 7.7 0.18 10.1 5.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HalX PF08663.5 EMC87246.1 - 0.16 11.9 5.4 0.24 11.4 0.7 2.5 1 1 1 2 2 2 0 HalX domain DUF2937 PF11157.3 EMC87246.1 - 0.19 11.0 6.9 0.096 12.0 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Bacillus_HBL PF05791.6 EMC87246.1 - 0.2 11.0 4.8 0.2 10.9 2.0 1.6 1 1 2 3 3 1 0 Bacillus haemolytic enterotoxin (HBL) Hemerythrin PF01814.18 EMC87246.1 - 0.2 11.7 9.5 0.85 9.7 0.9 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain CASP_C PF08172.7 EMC87246.1 - 0.21 10.5 8.3 2.9 6.8 5.8 2.0 1 1 0 1 1 1 0 CASP C terminal DUF342 PF03961.8 EMC87246.1 - 0.23 9.8 7.6 0.28 9.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_32 PF13654.1 EMC87246.1 - 0.23 10.0 9.2 0.27 9.8 6.4 1.1 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 EMC87246.1 - 0.32 10.5 13.5 0.11 12.0 7.4 1.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EMC87246.1 - 0.34 8.6 7.4 0.38 8.5 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 EMC87246.1 - 0.36 10.6 7.4 0.46 10.2 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EMC87246.1 - 0.37 10.6 2.5 0.61 9.9 1.7 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 EMC87246.1 - 0.37 10.6 17.1 0.35 10.6 9.5 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EMC87246.1 - 0.38 10.8 10.8 4.6 7.3 4.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EMC87246.1 - 0.4 10.5 20.7 0.75 9.6 9.9 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 EMC87246.1 - 0.4 9.5 5.4 0.49 9.2 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF445 PF04286.7 EMC87246.1 - 0.46 9.9 9.2 0.51 9.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Prefoldin_2 PF01920.15 EMC87246.1 - 0.47 10.2 17.9 0.41 10.4 2.6 3.1 1 1 1 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 EMC87246.1 - 0.49 10.5 8.0 0.66 10.1 1.1 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EMC87246.1 - 0.52 8.7 7.6 0.58 8.5 5.2 1.1 1 0 0 1 1 1 0 AAA domain CCDC-167 PF15188.1 EMC87246.1 - 0.56 10.1 13.7 0.47 10.4 2.2 2.7 1 1 2 3 3 2 0 Coiled-coil domain-containing protein 167 DUF4618 PF15397.1 EMC87246.1 - 0.58 9.4 14.3 1.3 8.3 6.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF3450 PF11932.3 EMC87246.1 - 0.76 8.9 10.6 1.3 8.1 7.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 EMC87246.1 - 0.81 9.5 20.6 2.3 8.0 1.3 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EMC87246.1 - 0.87 9.1 19.5 2.7 7.5 13.5 1.8 1 1 0 1 1 1 0 IncA protein TSC22 PF01166.13 EMC87246.1 - 0.9 9.5 9.1 2.8 7.9 0.2 3.4 1 1 2 3 3 3 0 TSC-22/dip/bun family TMPIT PF07851.8 EMC87246.1 - 0.95 8.4 5.4 1.1 8.2 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.17 EMC87246.1 - 1 9.4 13.6 1.6 8.7 7.0 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sec2p PF06428.6 EMC87246.1 - 1.4 8.8 15.0 3.9 7.3 6.5 2.9 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Allexi_40kDa PF05549.6 EMC87246.1 - 1.4 8.1 5.3 2 7.6 3.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein CorA PF01544.13 EMC87246.1 - 1.4 7.8 6.7 1.8 7.5 4.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF972 PF06156.8 EMC87246.1 - 1.8 8.9 14.7 1.6 9.0 3.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Med9 PF07544.8 EMC87246.1 - 2 8.2 12.4 2.2 8.0 6.3 2.7 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fzo_mitofusin PF04799.8 EMC87246.1 - 2 7.7 6.8 1.9 7.8 2.5 1.9 1 1 1 2 2 2 0 fzo-like conserved region Syntaxin PF00804.20 EMC87246.1 - 2.1 8.5 10.6 5.3 7.2 7.4 1.8 1 1 0 1 1 1 0 Syntaxin Val_tRNA-synt_C PF10458.4 EMC87246.1 - 2.2 8.3 10.9 0.64 10.1 0.8 3.1 1 1 3 4 4 4 0 Valyl tRNA synthetase tRNA binding arm COG5 PF10392.4 EMC87246.1 - 2.6 8.0 9.2 1.8 8.5 5.1 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ACCA PF03255.9 EMC87246.1 - 2.7 7.5 9.1 0.87 9.1 3.7 2.0 2 1 0 2 2 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HemX PF04375.9 EMC87246.1 - 3.1 6.3 12.3 3.1 6.2 6.5 1.8 1 1 1 2 2 2 0 HemX CENP-Q PF13094.1 EMC87246.1 - 3.8 7.5 19.1 0.48 10.4 8.3 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FemAB PF02388.11 EMC87246.1 - 4.2 5.9 7.4 12 4.4 5.1 1.8 1 1 0 1 1 1 0 FemAB family DUF4600 PF15372.1 EMC87246.1 - 4.2 7.5 16.0 8.6 6.5 0.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) GAS PF13851.1 EMC87246.1 - 4.4 6.4 17.7 4.4 6.4 7.9 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FUSC PF04632.7 EMC87246.1 - 4.5 5.5 4.8 5.8 5.2 3.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MRP-S26 PF14943.1 EMC87246.1 - 5.5 6.5 15.0 7.9 6.0 7.4 2.1 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 APG6 PF04111.7 EMC87246.1 - 6.5 5.7 13.4 8.8 5.2 9.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EMC87246.1 - 6.9 6.2 18.1 10 5.6 3.1 3.3 1 1 2 3 3 3 0 Septum formation initiator DUF4404 PF14357.1 EMC87246.1 - 6.9 7.1 11.2 2.9 8.3 4.8 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) Mnd1 PF03962.10 EMC87246.1 - 7 6.2 15.3 3.3 7.3 6.8 2.0 1 1 1 2 2 2 0 Mnd1 family Atg14 PF10186.4 EMC87246.1 - 7.5 5.3 18.3 4.3 6.1 0.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GP41 PF00517.12 EMC87246.1 - 7.7 6.0 7.7 17 4.9 2.8 2.0 1 1 1 2 2 2 0 Retroviral envelope protein GrpE PF01025.14 EMC87246.1 - 8.5 5.8 14.5 2.1 7.8 2.8 2.7 1 1 1 2 2 2 0 GrpE DUF641 PF04859.7 EMC87246.1 - 9 6.0 13.7 6.2 6.5 4.7 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PX PF00787.19 EMC87247.1 - 1.7e-19 69.6 0.1 3e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 PX domain DUF3457 PF11939.3 EMC87247.1 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) RRM_1 PF00076.17 EMC87248.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC87248.1 - 0.0014 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F5_F8_type_C PF00754.20 EMC87249.1 - 5.9e-13 48.7 0.0 6.7e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Collagen PF01391.13 EMC87250.1 - 1.3e-18 66.2 103.7 0.0027 17.2 4.0 7.7 1 1 4 5 5 5 4 Collagen triple helix repeat (20 copies) Ribosomal_S14 PF00253.16 EMC87251.1 - 4.6e-14 51.5 1.5 4.7e-14 51.5 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e LRR_4 PF12799.2 EMC87252.1 - 5.6e-21 73.7 10.4 1.3e-09 37.4 0.2 4.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC87252.1 - 1.3e-13 50.4 17.0 2e-08 33.8 1.9 3.3 2 1 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EMC87252.1 - 6.1e-13 46.6 13.2 0.014 15.5 0.1 7.8 7 0 0 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 EMC87252.1 - 2.4e-11 42.0 17.6 0.018 14.9 0.0 7.6 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.1 EMC87252.1 - 1.2e-05 24.8 13.1 0.82 9.9 0.0 6.7 6 1 1 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.1 EMC87252.1 - 0.13 11.8 2.6 0.48 9.9 0.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeat SapA PF02199.10 EMC87252.1 - 0.13 12.0 1.8 0.28 10.9 1.3 1.6 1 0 0 1 1 1 0 Saposin A-type domain DNA_pol_E_B PF04042.11 EMC87254.1 - 1.7e-52 177.7 1.2 3e-52 176.9 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 EMC87254.1 - 6.4e-19 67.6 0.3 1.4e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Kelch_3 PF13415.1 EMC87255.1 - 4.8e-32 109.3 18.5 3e-07 30.4 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC87255.1 - 5.8e-32 109.2 20.2 3.9e-09 36.1 0.5 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EMC87255.1 - 3.7e-26 90.1 19.2 3.7e-07 30.0 0.1 6.7 4 1 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMC87255.1 - 2.7e-19 68.6 4.4 0.00071 19.4 0.1 5.9 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 EMC87255.1 - 1.4e-18 66.1 10.0 4.4e-05 22.9 0.3 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EMC87255.1 - 4.9e-17 60.9 18.5 2.3e-06 27.1 0.0 6.1 5 2 1 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EMC87256.1 - 6.2e-31 105.9 24.2 4.8e-10 39.0 0.0 7.8 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC87256.1 - 6.1e-30 102.6 15.5 2.1e-06 27.7 0.2 8.0 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC87256.1 - 7.9e-24 83.1 14.1 3.5e-05 23.6 0.0 7.4 7 2 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EMC87256.1 - 1.5e-22 78.7 13.9 9.2e-07 28.7 0.0 7.0 6 1 1 7 7 7 3 Kelch motif Kelch_1 PF01344.20 EMC87256.1 - 4e-18 64.6 13.7 0.0011 18.4 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EMC87256.1 - 1.6e-14 52.9 19.3 0.00011 21.7 0.0 7.0 6 1 0 6 6 6 5 Kelch motif Rax2 PF12768.2 EMC87256.1 - 0.013 14.7 0.0 0.039 13.1 0.0 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Arf PF00025.16 EMC87257.1 - 1e-78 262.5 0.1 1.2e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC87257.1 - 1.6e-14 53.6 0.0 1.8e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMC87257.1 - 2.9e-13 49.4 0.0 3.5e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMC87257.1 - 9.7e-12 44.2 1.3 4.4e-08 32.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMC87257.1 - 1.1e-10 41.0 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMC87257.1 - 5.1e-08 33.4 0.0 7.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC87257.1 - 0.00023 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC87257.1 - 0.0023 17.4 0.1 0.016 14.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EMC87257.1 - 0.0042 16.2 0.2 0.0063 15.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Methyltransf_16 PF10294.4 EMC87258.1 - 4e-31 107.7 0.0 4.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMC87258.1 - 0.099 12.3 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RasGEF PF00617.14 EMC87259.1 - 6.3e-51 172.7 0.7 1.3e-50 171.7 0.5 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMC87259.1 - 8e-32 109.4 1.4 7.2e-31 106.3 0.0 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif RhoGEF PF00621.15 EMC87259.1 - 7.1e-18 65.1 1.5 7.1e-18 65.1 1.1 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EMC87259.1 - 9e-11 41.9 0.2 7.2e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 PH domain Histone PF00125.19 EMC87259.1 - 2e-07 31.0 0.0 5.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH_10 PF15411.1 EMC87259.1 - 0.013 15.6 0.1 0.05 13.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.1 EMC87259.1 - 0.12 12.4 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DAO PF01266.19 EMC87260.1 - 1.1e-44 152.8 0.0 1.3e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase LRR_8 PF13855.1 EMC87261.1 - 0.015 15.0 0.3 0.47 10.2 0.1 2.4 1 1 1 2 2 2 0 Leucine rich repeat Pkinase PF00069.20 EMC87262.1 - 6.1e-74 248.4 0.0 7.2e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87262.1 - 4.4e-32 111.1 0.0 2.8e-31 108.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC87262.1 - 0.024 14.3 0.4 0.093 12.4 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMC87262.1 - 0.14 11.0 0.1 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GBP PF02263.14 EMC87263.1 - 7.2e-88 293.9 0.0 9.7e-88 293.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 EMC87263.1 - 3.4e-06 26.4 0.1 5.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tic20 PF09685.5 EMC87263.1 - 0.027 14.4 1.3 0.064 13.2 0.9 1.5 1 0 0 1 1 1 0 Tic20-like protein WW PF00397.21 EMC87264.1 - 2.4e-14 52.8 14.4 2.6e-09 36.7 3.4 3.6 3 0 0 3 3 3 2 WW domain Suppressor_APC PF11414.3 EMC87264.1 - 0.66 9.7 7.5 0.14 11.9 2.1 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein TSC22 PF01166.13 EMC87265.1 - 0.00048 20.0 2.4 0.00048 20.0 1.7 10.7 6 3 4 11 11 11 3 TSC-22/dip/bun family TMF_TATA_bd PF12325.3 EMC87265.1 - 0.0024 17.6 8.9 0.0024 17.6 6.2 8.7 3 3 6 9 9 9 2 TATA element modulatory factor 1 TATA binding DUF2205 PF10224.4 EMC87265.1 - 0.0093 15.5 0.4 0.0093 15.5 0.3 9.1 5 4 4 9 9 9 2 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 EMC87265.1 - 0.01 15.4 12.1 0.01 15.4 8.4 6.8 1 1 5 6 6 6 0 IncA protein Tropomyosin_1 PF12718.2 EMC87265.1 - 0.01 15.6 29.6 0.01 15.6 20.5 7.9 1 1 6 7 7 7 0 Tropomyosin like DUF904 PF06005.7 EMC87265.1 - 0.02 15.1 9.6 0.02 15.1 6.6 11.5 4 4 6 10 10 10 0 Protein of unknown function (DUF904) Myosin_tail_1 PF01576.14 EMC87265.1 - 0.95 7.0 120.5 0.094 10.4 47.4 3.5 1 1 1 3 3 3 0 Myosin tail Abhydrolase_5 PF12695.2 EMC87267.1 - 8.1e-12 45.1 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC87267.1 - 1.7e-09 37.9 0.0 3.1e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC87267.1 - 7.9e-06 25.5 0.0 0.00043 19.9 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMC87267.1 - 2.2e-05 24.1 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMC87267.1 - 0.0014 18.8 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EMC87267.1 - 0.006 16.1 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EMC87267.1 - 0.011 15.2 0.1 0.29 10.5 0.0 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMC87267.1 - 0.045 12.9 0.0 0.092 11.9 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Cutinase PF01083.17 EMC87267.1 - 0.064 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF676 PF05057.9 EMC87267.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Phosphorylase PF00343.15 EMC87268.1 - 0 1042.5 0.1 0 1042.3 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase SPRY PF00622.23 EMC87269.1 - 1.6e-11 44.3 0.0 3e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 SPRY domain fn3 PF00041.16 EMC87269.1 - 1.1e-09 38.3 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.1 EMC87269.1 - 0.00084 18.8 0.1 0.0023 17.3 0.0 1.8 1 1 1 2 2 2 1 SPRY-associated domain ATP-synt_E_2 PF08112.6 EMC87269.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase epsilon subunit BLOC1_2 PF10046.4 EMC87269.1 - 0.34 11.0 2.1 15 5.8 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 EMC87269.1 - 0.35 10.8 3.1 0.5 10.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Nup54 PF13874.1 EMC87269.1 - 0.53 9.9 3.9 0.98 9.0 2.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 7tm_1 PF00001.16 EMC87271.1 - 7.7e-15 54.7 2.0 9.8e-15 54.3 1.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-CCCH PF00642.19 EMC87272.1 - 1.1e-10 40.8 22.1 0.00019 21.0 0.5 4.6 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GCK PF07802.6 EMC87272.1 - 5.9 7.0 9.0 1.2 9.2 1.3 2.4 2 0 0 2 2 2 0 GCK domain 7tm_1 PF00001.16 EMC87273.1 - 5.8e-42 143.6 25.0 7e-42 143.3 17.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC87274.1 - 1.7e-39 135.5 23.8 2.5e-39 134.9 16.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CopD PF05425.8 EMC87274.1 - 0.0075 16.4 0.8 0.019 15.1 0.5 1.7 1 0 0 1 1 1 1 Copper resistance protein D DUF898 PF05987.8 EMC87274.1 - 5.2 5.8 21.6 0.035 12.9 4.7 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Sulfotransfer_2 PF03567.9 EMC87275.1 - 1.4e-50 172.3 1.3 1.4e-50 172.3 0.9 1.4 2 0 0 2 2 2 1 Sulfotransferase family UDP-g_GGTase PF06427.6 EMC87276.1 - 2.2e-78 262.4 0.3 6.2e-77 257.6 0.1 3.1 4 0 0 4 4 4 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EMC87276.1 - 1.2e-08 34.5 0.8 3.7e-08 33.0 0.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 TPR_11 PF13414.1 EMC87277.1 - 2.4e-42 142.4 22.0 1.1e-11 44.1 0.7 6.3 4 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 EMC87277.1 - 2.9e-33 111.0 20.7 0.0002 20.9 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.23 EMC87277.1 - 1.5e-32 109.8 21.9 6.2e-07 28.7 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87277.1 - 1.5e-31 108.3 12.4 2.8e-06 27.8 0.6 6.8 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87277.1 - 1.9e-27 95.3 19.6 1.7e-06 28.2 0.7 6.9 3 3 4 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 EMC87277.1 - 4.5e-22 77.5 4.7 3.3e-21 74.7 1.6 3.1 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.1 EMC87277.1 - 4.7e-22 76.4 11.3 0.022 15.3 0.0 10.0 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87277.1 - 3.7e-19 66.9 22.0 9.8e-05 21.8 0.0 8.9 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EMC87277.1 - 8.7e-18 63.9 10.4 3.4e-05 23.6 0.2 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87277.1 - 3.6e-15 54.8 10.7 0.00082 19.3 0.0 7.6 9 0 0 9 9 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EMC87277.1 - 4.4e-15 55.5 24.9 1.1e-05 25.5 0.7 5.4 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EMC87277.1 - 2.2e-13 49.9 23.4 0.0034 17.3 0.2 7.4 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 EMC87277.1 - 1.9e-12 46.7 18.4 0.077 13.4 0.0 9.8 9 2 0 9 9 8 3 Tetratricopeptide repeat TPR_20 PF14561.1 EMC87277.1 - 3.8e-10 39.7 23.3 0.083 13.0 0.0 7.6 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC87277.1 - 2.6e-08 33.0 17.3 3.8 7.5 0.2 8.8 7 2 1 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC87277.1 - 4.5e-05 23.2 12.4 0.25 11.2 0.3 6.2 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat COPI_C PF06957.6 EMC87277.1 - 0.00033 19.3 0.5 0.37 9.2 0.0 2.8 2 1 2 4 4 4 2 Coatomer (COPI) alpha subunit C-terminus NARP1 PF12569.3 EMC87277.1 - 0.0048 15.7 2.5 0.0048 15.7 1.7 3.6 1 1 3 4 4 3 1 NMDA receptor-regulated protein 1 DUF3887 PF13026.1 EMC87277.1 - 0.006 16.8 0.3 0.006 16.8 0.2 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3887) DUF4363 PF14276.1 EMC87277.1 - 0.046 13.4 0.2 0.046 13.4 0.1 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF4363) Alkyl_sulf_dimr PF14863.1 EMC87277.1 - 0.12 12.5 0.2 0.12 12.5 0.2 4.3 1 1 1 4 4 4 0 Alkyl sulfatase dimerisation TPR_4 PF07721.9 EMC87277.1 - 0.18 12.3 13.3 1.1 9.8 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Virulence_fact PF13769.1 EMC87277.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.6 4 1 1 5 5 5 0 Virulence factor MAS20 PF02064.10 EMC87277.1 - 0.25 11.2 15.1 3.5 7.5 0.0 5.1 2 2 3 6 6 6 0 MAS20 protein import receptor PMP22_Claudin PF00822.15 EMC87279.1 - 2.4e-26 92.3 8.3 3.2e-26 91.9 5.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC87279.1 - 3.8e-05 23.4 10.5 5.2e-05 23.0 7.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Kelch_6 PF13964.1 EMC87279.1 - 0.054 13.6 0.1 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Kelch motif DUF4282 PF14110.1 EMC87279.1 - 0.17 12.1 1.0 0.34 11.1 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) PIRT PF15099.1 EMC87279.1 - 0.59 9.3 2.5 1.1 8.5 1.7 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family ABC_membrane PF00664.18 EMC87280.1 - 3.9e-71 239.6 39.5 1.6e-38 132.7 9.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC87280.1 - 5.3e-57 191.9 0.0 7.4e-31 107.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC87280.1 - 2.8e-12 46.3 2.1 0.01 15.1 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC87280.1 - 1.1e-09 38.7 0.4 0.0042 17.0 0.0 4.6 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 EMC87280.1 - 2.8e-08 33.9 0.8 0.00058 19.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMC87280.1 - 6.2e-08 32.0 0.0 0.0057 16.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EMC87280.1 - 1.9e-07 31.0 0.3 0.0044 16.9 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EMC87280.1 - 5e-07 30.2 0.0 0.0079 16.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EMC87280.1 - 5.3e-06 26.3 0.0 0.0079 16.0 0.0 2.8 2 0 0 2 2 2 2 Dynamin family DUF258 PF03193.11 EMC87280.1 - 5.5e-06 25.6 0.0 0.039 13.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EMC87280.1 - 4.5e-05 22.4 0.0 0.013 14.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 EMC87280.1 - 5.8e-05 23.5 0.0 0.62 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMC87280.1 - 0.00011 22.3 3.8 0.78 9.8 0.1 4.2 4 1 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 EMC87280.1 - 0.00068 19.4 0.3 0.043 13.4 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 EMC87280.1 - 0.00069 20.4 0.8 1.7 9.4 0.1 3.0 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.12 EMC87280.1 - 0.00095 19.0 0.4 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 EMC87280.1 - 0.0018 17.9 0.3 8 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EMC87280.1 - 0.0019 17.6 0.0 0.83 9.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMC87280.1 - 0.0024 16.9 0.3 1.4 7.9 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 EMC87280.1 - 0.0038 16.9 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EMC87280.1 - 0.008 15.6 0.3 3 7.2 0.0 3.4 4 0 0 4 4 4 1 IstB-like ATP binding protein cobW PF02492.14 EMC87280.1 - 0.014 14.8 0.3 2.2 7.6 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EMC87280.1 - 0.018 13.8 0.2 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 EMC87280.1 - 0.022 14.2 1.9 7.4 5.9 0.0 3.3 2 1 1 3 3 3 0 AAA-like domain DUF815 PF05673.8 EMC87280.1 - 0.023 13.6 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.1 EMC87280.1 - 0.033 13.2 0.0 12 4.8 0.0 3.2 3 1 1 4 4 4 0 AAA ATPase domain AAA_18 PF13238.1 EMC87280.1 - 0.042 14.1 0.1 8.4 6.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EMC87280.1 - 0.067 13.0 0.1 10 6.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMC87280.1 - 0.089 12.2 0.0 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.24 EMC87280.1 - 0.1 12.7 1.3 9.8 6.3 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.16 EMC87280.1 - 0.11 11.8 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_19 PF13245.1 EMC87280.1 - 0.17 11.6 0.4 4.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain DUF4637 PF15470.1 EMC87281.1 - 0.0033 17.0 13.5 0.0033 17.0 9.3 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4637) SAPS PF04499.10 EMC87281.1 - 0.059 12.0 19.1 0.069 11.7 13.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DHHW PF14286.1 EMC87281.1 - 3.5 6.8 15.0 4.8 6.3 10.4 1.2 1 0 0 1 1 1 0 DHHW protein Hid1 PF12722.2 EMC87281.1 - 5.1 4.6 23.4 6 4.4 16.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 EMC87281.1 - 6.9 5.7 26.0 8.8 5.3 18.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein HMG_box PF00505.14 EMC87282.1 - 5e-18 65.1 4.2 1e-17 64.1 2.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC87282.1 - 5.5e-06 26.6 2.6 1.2e-05 25.5 1.8 1.5 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.3 EMC87282.1 - 0.0034 17.9 1.1 0.0082 16.7 0.8 1.6 1 0 0 1 1 1 1 SOX transcription factor GpcrRhopsn4 PF10192.4 EMC87283.1 - 3.1e-80 269.0 5.9 3.8e-80 268.7 4.1 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 EMC87283.1 - 8.1e-09 34.8 2.8 1.6e-08 33.8 1.8 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor PLAC8 PF04749.12 EMC87283.1 - 0.0093 16.5 2.7 0.0093 16.5 1.9 3.1 2 1 0 2 2 2 1 PLAC8 family DUF2567 PF10821.3 EMC87283.1 - 0.034 13.6 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) MraZ PF02381.13 EMC87283.1 - 0.039 13.7 0.5 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 MraZ protein Epimerase PF01370.16 EMC87284.1 - 1e-58 198.5 0.0 1.2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC87284.1 - 2.8e-26 92.0 0.0 3.4e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMC87284.1 - 1.2e-23 83.4 0.0 4.8e-23 81.4 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMC87284.1 - 1.3e-21 76.5 0.0 1.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMC87284.1 - 2.9e-18 65.6 0.0 4.2e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMC87284.1 - 1.6e-07 31.4 0.0 2.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Tyrosinase PF00264.15 EMC87285.1 - 8.5e-20 71.8 0.0 1.4e-19 71.1 0.0 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Glypican PF01153.14 EMC87286.1 - 1.3e-29 103.3 0.1 1.3e-29 103.2 0.1 1.0 1 0 0 1 1 1 1 Glypican TGF_beta_GS PF08515.7 EMC87286.1 - 0.11 11.8 3.8 0.18 11.1 2.6 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Yae1_N PF09811.4 EMC87287.1 - 1.7e-08 33.8 39.4 61 3.2 22.3 4.2 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Glypican PF01153.14 EMC87289.1 - 3.9e-147 491.2 0.4 4.8e-147 490.9 0.2 1.0 1 0 0 1 1 1 1 Glypican LRR_4 PF12799.2 EMC87290.1 - 3e-29 100.1 49.2 3.9e-09 35.9 0.9 9.1 7 1 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC87290.1 - 4.5e-23 80.7 27.3 6.8e-08 32.1 2.8 6.7 6 0 0 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EMC87290.1 - 1.1e-08 33.9 36.4 0.3 11.2 0.1 11.6 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC87290.1 - 5.2 7.7 51.1 1.1 9.7 0.2 11.5 13 0 0 13 13 13 0 Leucine rich repeat RRM_1 PF00076.17 EMC87291.1 - 1.5e-43 146.2 0.2 8.1e-19 67.0 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC87291.1 - 7.6e-30 102.7 0.0 5e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC87291.1 - 1.4e-24 85.6 0.3 7.4e-10 38.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC87291.1 - 0.0017 18.1 0.0 0.6 9.9 0.0 2.9 2 0 0 2 2 2 2 RNA binding motif OB_RNB PF08206.6 EMC87291.1 - 0.016 14.6 0.0 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain RseA_C PF03873.8 EMC87291.1 - 0.022 14.6 0.3 0.081 12.8 0.2 2.0 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Pkinase_Tyr PF07714.12 EMC87294.1 - 3.8e-17 62.2 0.0 4.1e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC87294.1 - 1.1e-16 60.7 0.1 1.8e-16 60.1 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain C6_DPF PF10170.4 EMC87295.1 - 0.034 14.1 1.6 1.1 9.3 0.0 3.0 1 1 2 3 3 3 0 Cysteine-rich domain Fer4_11 PF13247.1 EMC87295.1 - 0.15 11.9 8.2 0.65 9.9 0.3 4.5 2 2 4 6 6 6 0 4Fe-4S dicluster domain Plectin PF00681.15 EMC87296.1 - 3.1e-44 148.2 0.0 5.2e-18 64.2 0.0 5.6 4 1 1 5 5 5 4 Plectin repeat Phage_XkdX PF09693.5 EMC87296.1 - 1.5e-07 30.8 3.5 1.4 8.5 0.1 4.6 4 0 0 4 4 4 3 Phage uncharacterised protein (Phage_XkdX) GatB_Yqey PF02637.13 EMC87296.1 - 2.1e-07 30.7 17.0 1 9.0 0.1 6.7 7 0 0 7 7 7 4 GatB domain Nitr_red_alph_N PF14710.1 EMC87296.1 - 0.00017 21.7 2.2 10 6.4 0.0 3.7 3 0 0 3 3 3 3 Respiratory nitrate reductase alpha N-terminal tify PF06200.9 EMC87296.1 - 0.0041 16.3 0.0 3.6 6.9 0.0 3.9 4 0 0 4 4 4 1 tify domain DUF2095 PF09868.4 EMC87296.1 - 0.0073 16.0 1.5 49 3.6 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2095) DUF4148 PF13663.1 EMC87296.1 - 0.038 13.8 17.4 14 5.5 0.2 7.2 7 0 0 7 7 7 0 Domain of unknown function (DUF4148) Clr5 PF14420.1 EMC87296.1 - 0.13 12.2 14.7 24 4.9 0.2 6.4 8 0 0 8 8 8 0 Clr5 domain zf-HC2 PF13490.1 EMC87296.1 - 0.13 12.2 23.3 11 6.0 0.0 7.7 8 0 0 8 8 8 0 Putative zinc-finger Biliv-reduc_cat PF09166.5 EMC87296.1 - 5.1 7.1 7.4 31 4.6 0.1 3.3 3 0 0 3 3 3 0 Biliverdin reductase, catalytic Plectin PF00681.15 EMC87298.1 - 3.3e-94 308.1 1.3 1.7e-20 72.2 0.0 10.3 9 1 1 10 10 10 5 Plectin repeat PG_binding_1 PF01471.13 EMC87298.1 - 0.00026 20.8 0.3 42 4.2 0.0 5.4 5 0 0 5 5 5 0 Putative peptidoglycan binding domain TfuA PF07812.7 EMC87298.1 - 0.0045 16.4 0.0 5.3 6.5 0.0 3.6 2 2 2 4 4 4 2 TfuA-like protein HTH_10 PF04967.7 EMC87298.1 - 0.0055 16.2 0.1 9.8 5.8 0.0 3.6 4 0 0 4 4 4 2 HTH DNA binding domain NADH_dh_m_C1 PF15088.1 EMC87298.1 - 0.086 12.3 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DUF4099 PF13351.1 EMC87298.1 - 0.12 12.3 0.0 31 4.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4099) Pkinase PF00069.20 EMC87299.1 - 3e-31 108.5 0.0 4.1e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87299.1 - 9.5e-13 47.8 0.0 1.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC87299.1 - 8.2e-05 22.4 0.0 0.00062 19.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMC87299.1 - 0.026 13.3 0.2 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glypican PF01153.14 EMC87300.1 - 3.7e-116 388.9 3.6 4.1e-116 388.8 2.5 1.0 1 0 0 1 1 1 1 Glypican zf-TFIIB PF13453.1 EMC87300.1 - 0.075 12.2 1.6 0.16 11.1 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger MYEOV2 PF15004.1 EMC87301.1 - 1.2e-33 115.4 6.0 1.2e-33 115.3 4.2 1.0 1 0 0 1 1 1 1 Myeloma-overexpressed-like C1q PF00386.16 EMC87302.1 - 7.3e-41 139.1 0.6 8.9e-41 138.8 0.4 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC87302.1 - 1.3e-10 40.6 32.5 2.2e-09 36.7 22.5 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) PPV_E2_N PF00508.12 EMC87302.1 - 0.042 13.0 0.6 0.056 12.6 0.4 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal Glyco_transf_29 PF00777.13 EMC87303.1 - 7.3e-63 212.2 0.0 1.1e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) 7tm_1 PF00001.16 EMC87304.1 - 1.5e-23 83.2 11.2 2e-23 82.8 7.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87304.1 - 0.0014 17.8 10.0 0.0017 17.5 6.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1705 PF08019.7 EMC87304.1 - 0.17 11.3 7.6 0.77 9.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) DUF1049 PF06305.6 EMC87304.1 - 1.1 8.7 5.9 2.1 7.8 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) 7tm_1 PF00001.16 EMC87305.1 - 1.7e-32 112.5 27.1 2.2e-32 112.2 18.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC87306.1 - 7e-38 130.2 15.2 8.5e-38 129.9 10.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC87306.1 - 9.1e-05 21.7 8.0 0.00027 20.1 2.7 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv H_PPase PF03030.11 EMC87306.1 - 0.14 10.3 1.1 0.26 9.4 0.3 1.6 1 1 1 2 2 2 0 Inorganic H+ pyrophosphatase 7tm_1 PF00001.16 EMC87307.1 - 1e-39 136.2 29.3 1.3e-39 135.9 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC87308.1 - 2.4e-36 125.1 21.4 2.8e-36 124.9 14.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BRICHOS PF04089.9 EMC87309.1 - 5.8e-30 103.0 0.0 8.3e-30 102.5 0.0 1.2 1 0 0 1 1 1 1 BRICHOS domain Mo25 PF08569.6 EMC87310.1 - 4.6e-145 482.8 14.7 5.2e-145 482.6 10.2 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 EMC87310.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats HLH PF00010.21 EMC87311.1 - 1.8e-14 53.1 1.6 3.7e-14 52.1 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 EMC87311.1 - 2.5e-07 30.3 0.0 5.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Hairy Orange Period_C PF12114.3 EMC87312.1 - 2.3e-79 265.5 4.9 2.3e-79 265.5 3.4 4.1 3 1 1 4 4 4 1 Period protein 2/3C-terminal region PAS_11 PF14598.1 EMC87312.1 - 1.3e-11 44.4 0.0 4.4e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 EMC87312.1 - 1.8e-09 37.5 0.0 5e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EMC87312.1 - 6.1e-06 25.9 0.0 0.00027 20.6 0.0 2.7 2 0 0 2 2 2 1 PAS fold Synaptobrevin PF00957.16 EMC87313.1 - 2.3e-35 120.0 3.9 2.8e-35 119.7 2.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Spore_III_AB PF09548.5 EMC87313.1 - 0.037 13.7 0.9 0.054 13.2 0.3 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ATP-synt_F6 PF05511.6 EMC87313.1 - 0.075 12.9 0.1 0.096 12.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 CD34_antigen PF06365.7 EMC87313.1 - 0.076 12.6 0.5 0.082 12.5 0.3 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family ERM PF00769.14 EMC87313.1 - 0.08 12.4 1.6 0.099 12.1 1.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tweety PF04906.8 EMC87313.1 - 0.088 11.2 0.7 0.094 11.1 0.5 1.0 1 0 0 1 1 1 0 Tweety DUF912 PF06024.7 EMC87313.1 - 0.12 12.4 0.5 0.17 11.9 0.4 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Seryl_tRNA_N PF02403.17 EMC87313.1 - 0.18 11.8 2.1 0.4 10.7 1.4 1.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PI3Ka PF00613.15 EMC87314.1 - 3.7e-62 208.7 1.3 8.1e-62 207.6 0.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EMC87314.1 - 8.4e-58 195.6 0.0 1.4e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.11 EMC87314.1 - 2.8e-37 125.9 0.1 1.6e-36 123.5 0.0 2.3 2 0 0 2 2 2 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.13 EMC87314.1 - 1.2e-31 108.8 0.1 2.7e-31 107.6 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 EMC87314.1 - 4.5e-25 88.1 0.0 8.5e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 RWD PF05773.17 EMC87314.1 - 0.061 13.2 0.1 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 RWD domain Fork_head PF00250.13 EMC87315.1 - 1.6e-41 140.2 0.1 2.3e-41 139.7 0.1 1.2 1 0 0 1 1 1 1 Fork head domain Coatomer_WDAD PF04053.9 EMC87316.1 - 2.2e-169 563.9 0.0 3.6e-169 563.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EMC87316.1 - 4.6e-56 184.8 6.1 4.3e-13 48.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Lipocalin PF00061.18 EMC87317.1 - 5.1e-18 65.4 4.0 5.7e-18 65.2 2.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 EMC87317.1 - 4e-08 33.0 0.3 4.6e-08 32.8 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 EMC87318.1 - 5.1e-18 65.4 0.3 5.9e-18 65.2 0.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 EMC87318.1 - 2.2e-05 24.1 0.2 2.7e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family CTP_transf_2 PF01467.21 EMC87319.1 - 2.8e-26 92.4 0.0 5e-26 91.6 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase DARPP-32 PF05395.7 EMC87320.1 - 3.7e-35 121.6 3.6 4.2e-35 121.4 2.5 1.0 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 Collagen PF01391.13 EMC87322.1 - 3e-26 90.7 73.1 1.6e-08 33.9 8.6 5.1 2 1 3 5 5 5 5 Collagen triple helix repeat (20 copies) Trypan_PARP PF05887.6 EMC87325.1 - 1.2 8.9 17.1 0.024 14.4 4.7 2.9 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.1 EMC87326.1 - 2.7e-40 135.9 32.1 5.6e-14 51.6 7.3 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EMC87326.1 - 1.9e-19 68.8 14.6 1.9e-05 24.1 3.9 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC87326.1 - 7.5e-16 55.7 15.5 0.01 15.7 0.0 7.9 8 0 0 8 8 7 5 Leucine Rich Repeat I-set PF07679.11 EMC87326.1 - 1.5e-15 56.7 0.0 3.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 EMC87326.1 - 6e-15 55.0 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) Ig_2 PF13895.1 EMC87326.1 - 6.9e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC87326.1 - 2.4e-07 31.1 0.0 5.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC87326.1 - 5.4e-06 26.4 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 EMC87326.1 - 7.2e-06 25.6 2.1 0.0014 18.2 0.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat fn3 PF00041.16 EMC87326.1 - 8.9e-05 22.5 0.1 0.00025 21.1 0.0 1.8 2 0 0 2 2 1 1 Fibronectin type III domain LRR_7 PF13504.1 EMC87326.1 - 0.0001 21.8 23.9 0.41 11.0 0.0 7.6 8 0 0 8 8 6 2 Leucine rich repeat V-set PF07686.12 EMC87326.1 - 0.0062 16.4 0.0 0.032 14.1 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.1 EMC87326.1 - 0.0086 16.0 21.4 3.1 8.1 0.0 6.7 8 0 0 8 8 7 2 Leucine Rich repeat C2-set_2 PF08205.7 EMC87326.1 - 0.022 14.6 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF240 PF03086.9 EMC87326.1 - 0.14 11.8 4.9 0.19 11.3 2.6 1.8 1 1 1 2 2 2 0 MG032/MG096/MG288 family 2 P12 PF12669.2 EMC87326.1 - 0.81 9.9 3.4 2.3 8.5 2.3 1.7 1 0 0 1 1 1 0 Virus attachment protein p12 family LSR PF05624.9 EMC87326.1 - 1.1 9.0 11.9 0.056 13.1 1.6 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Adipokin_hormo PF06377.6 EMC87328.1 - 0.61 10.2 9.8 3.7 7.7 0.2 2.9 2 1 0 2 2 2 0 Adipokinetic hormone FA_desaturase PF00487.19 EMC87328.1 - 1 8.7 10.2 2.3 7.5 0.7 2.5 2 0 0 2 2 2 0 Fatty acid desaturase DUF605 PF04652.11 EMC87329.1 - 6.4 6.0 12.3 7.3 5.8 8.5 1.1 1 0 0 1 1 1 0 Vta1 like Kelch_1 PF01344.20 EMC87330.1 - 2.6e-64 212.5 8.8 8.1e-15 54.0 0.1 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 EMC87330.1 - 3e-41 137.9 3.7 4.5e-09 36.0 0.0 5.5 2 2 3 5 5 5 5 Kelch motif BACK PF07707.10 EMC87330.1 - 5.2e-35 119.3 1.2 5.2e-35 119.3 0.9 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 EMC87330.1 - 1.6e-31 108.5 0.8 1.6e-31 108.5 0.6 2.1 3 0 0 3 3 3 1 BTB/POZ domain Kelch_2 PF07646.10 EMC87330.1 - 1.1e-24 85.1 7.3 0.00013 21.5 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_3 PF13415.1 EMC87330.1 - 1.3e-22 79.2 2.5 0.00013 22.0 0.0 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC87330.1 - 3.2e-17 62.0 7.4 1.8e-06 27.6 0.0 5.6 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC87330.1 - 1.5e-08 34.4 10.8 0.021 14.7 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Skp1_POZ PF03931.10 EMC87330.1 - 0.054 13.6 0.2 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain TPR_16 PF13432.1 EMC87331.1 - 3.9e-09 36.9 2.8 0.00083 19.9 0.2 2.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87331.1 - 1.4e-08 34.6 0.1 0.55 11.0 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87331.1 - 5.3e-07 29.8 0.1 0.02 15.2 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC87331.1 - 3.2e-06 26.6 0.7 0.63 10.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC87331.1 - 1.1e-05 25.0 1.0 0.0055 16.3 0.1 3.2 1 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.1 EMC87331.1 - 1.4e-05 24.9 1.2 0.008 16.0 0.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87331.1 - 0.00024 20.6 0.2 3.5 7.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC87331.1 - 0.0051 16.3 1.5 1.5 8.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87331.1 - 0.0075 16.3 0.0 5.3 7.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc5 PF12862.2 EMC87331.1 - 0.0093 15.7 1.0 0.23 11.2 0.2 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 5 Ribophorin_II PF05817.9 EMC87331.1 - 0.01 14.0 0.0 0.011 13.9 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II TPR_6 PF13174.1 EMC87331.1 - 0.012 15.9 0.1 13 6.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMC87331.1 - 0.023 14.6 0.3 0.16 11.9 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat PPR PF01535.15 EMC87331.1 - 0.026 14.4 0.2 2.1 8.4 0.1 3.1 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.2 EMC87331.1 - 0.033 13.6 0.2 5.4 6.5 0.1 2.8 3 0 0 3 3 3 0 PPR repeat DUF4226 PF10774.4 EMC87331.1 - 0.048 13.7 0.2 0.08 12.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4226) Apc3 PF12895.2 EMC87331.1 - 0.057 13.5 0.1 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EMC87331.1 - 0.096 12.6 1.8 4.1 7.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMC87331.1 - 0.47 10.3 2.2 11 6.0 0.1 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat FKBP_C PF00254.23 EMC87332.1 - 1.1e-32 111.9 0.1 1.3e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SOUL PF04832.7 EMC87333.1 - 2e-40 138.2 0.0 2.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Myb_DNA-binding PF00249.26 EMC87334.1 - 0.018 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain PDDEXK_4 PF14281.1 EMC87334.1 - 0.032 14.0 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily SANTA PF09133.5 EMC87335.1 - 7.9e-25 86.6 0.3 8.8e-25 86.5 0.2 1.0 1 0 0 1 1 1 1 SANTA (SANT Associated) Ras PF00071.17 EMC87336.1 - 1.4e-55 187.1 0.3 1.7e-55 186.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC87336.1 - 6.7e-15 55.6 0.1 1.6e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC87336.1 - 1.7e-10 40.4 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC87336.1 - 1.7e-05 24.3 0.1 7.2e-05 22.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC87336.1 - 0.0021 17.9 0.0 0.0039 17.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC87336.1 - 0.0041 16.3 0.1 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMC87336.1 - 0.0058 16.0 0.2 0.018 14.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EMC87336.1 - 0.015 14.3 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin ArgK PF03308.11 EMC87336.1 - 0.09 11.5 0.4 0.97 8.1 0.2 2.0 2 0 0 2 2 2 0 ArgK protein Med1 PF10744.4 EMC87337.1 - 1.8e-65 221.2 0.0 2.3e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 CTD_bind PF04818.8 EMC87337.1 - 0.081 13.1 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Yae1_N PF09811.4 EMC87338.1 - 1.4e-12 46.9 2.1 1.4e-12 46.9 1.5 1.6 2 0 0 2 2 2 1 Essential protein Yae1, N terminal DUF2385 PF09539.5 EMC87338.1 - 0.012 16.0 0.1 0.041 14.2 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2385) Clathrin PF00637.15 EMC87339.1 - 3.7e-23 81.7 1.7 3.7e-23 81.7 1.2 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.4 EMC87339.1 - 0.001 19.2 0.7 0.0029 17.7 0.5 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EMC87339.1 - 0.009 15.8 5.4 0.032 14.0 3.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC87339.1 - 0.032 14.3 2.7 0.1 12.6 1.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC87339.1 - 2 8.1 9.4 0.41 10.3 3.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87339.1 - 3.2 7.5 11.5 0.34 10.6 4.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain BAR PF03114.13 EMC87341.1 - 7.1e-53 179.4 7.5 1e-52 178.9 5.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EMC87341.1 - 1.1e-09 37.7 0.0 2.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC87341.1 - 4.2e-06 26.0 0.1 3.8e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC87341.1 - 5.6e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.8 EMC87341.1 - 0.0088 15.4 4.1 0.013 14.8 2.8 1.3 1 0 0 1 1 1 1 Arfaptin-like domain IFT57 PF10498.4 EMC87341.1 - 0.052 12.2 4.4 0.32 9.6 0.5 2.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 HD_3 PF13023.1 EMC87341.1 - 0.065 12.9 0.3 0.065 12.9 0.2 2.4 2 0 0 2 2 2 0 HD domain EzrA PF06160.7 EMC87341.1 - 0.18 9.9 5.2 1.2 7.1 0.3 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA GAS PF13851.1 EMC87341.1 - 0.24 10.5 4.4 4.9 6.2 0.9 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.8 EMC87341.1 - 1.3 9.8 6.7 9.7 6.9 0.6 2.5 2 0 0 2 2 2 0 Occludin homology domain V-set PF07686.12 EMC87342.1 - 1.4e-11 44.2 1.3 1.7e-11 44.0 0.9 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC87342.1 - 0.00049 20.1 4.3 0.011 15.7 3.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC87342.1 - 0.002 17.9 1.0 0.004 16.9 0.7 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC87342.1 - 0.039 14.0 0.3 0.052 13.6 0.2 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.1 EMC87342.1 - 0.3 11.6 3.7 0.81 10.2 2.6 1.8 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC87343.1 - 3.8e-17 62.2 0.0 5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC87343.1 - 3.9e-05 23.6 1.4 0.00034 20.6 1.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC87343.1 - 0.00051 19.8 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC87343.1 - 0.00062 19.8 0.0 0.00086 19.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC87343.1 - 0.0013 19.1 0.2 0.0034 17.8 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC87344.1 - 3.4e-10 39.8 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC87344.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC87344.1 - 0.047 13.5 0.0 0.076 12.8 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.12 EMC87345.1 - 3.6e-10 39.7 0.4 4.2e-10 39.5 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC87345.1 - 0.0014 18.4 0.3 0.0028 17.4 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC87345.1 - 0.0017 18.4 0.8 0.0034 17.4 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 EMC87345.1 - 0.027 14.5 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.1 EMC87345.1 - 0.13 12.7 1.6 0.62 10.6 1.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain RINGv PF12906.2 EMC87346.1 - 1.4e-15 57.0 17.0 3.7e-15 55.6 11.8 1.8 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.7 EMC87346.1 - 0.0017 18.1 0.9 0.0033 17.1 0.6 1.4 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component zf-RING_2 PF13639.1 EMC87346.1 - 0.01 15.6 16.3 0.01 15.6 11.3 2.7 3 0 0 3 3 3 0 Ring finger domain FANCL_C PF11793.3 EMC87346.1 - 5.2 7.1 12.1 3 7.8 6.4 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain ubiquitin PF00240.18 EMC87347.1 - 2e-17 62.3 0.0 4e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.11 EMC87347.1 - 4.4e-11 42.4 7.6 8.5e-11 41.5 5.3 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 EMC87347.1 - 1.2e-06 28.1 0.0 2.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC87347.1 - 3.6e-05 23.9 0.0 0.00012 22.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain KCl_Cotrans_1 PF03522.10 EMC87347.1 - 5.2 6.6 5.7 1.3 8.6 0.7 2.2 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) PSP94 PF05825.6 EMC87350.1 - 1.6e-21 76.4 8.7 1.7e-21 76.2 6.0 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) TILa PF12714.2 EMC87350.1 - 0.006 16.3 6.1 0.006 16.3 4.2 1.8 2 1 0 2 2 2 1 TILa domain VWC PF00093.13 EMC87350.1 - 0.2 11.8 9.6 0.66 10.1 6.6 1.8 1 1 0 1 1 1 0 von Willebrand factor type C domain Annexin PF00191.15 EMC87351.1 - 8.7e-98 320.2 14.0 8e-28 96.1 0.6 4.1 4 0 0 4 4 4 4 Annexin DUF445 PF04286.7 EMC87351.1 - 0.086 12.3 0.8 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FmdE PF02663.9 EMC87351.1 - 0.094 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CRS1_YhbY PF01985.16 EMC87351.1 - 0.14 12.1 0.6 0.68 9.9 0.0 2.4 3 0 0 3 3 3 0 CRS1 / YhbY (CRM) domain DUF2179 PF10035.4 EMC87351.1 - 0.24 11.0 1.3 2.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) Ant_C PF05586.6 EMC87352.1 - 3.1e-45 152.5 0.5 5.1e-45 151.8 0.3 1.4 1 0 0 1 1 1 1 Anthrax receptor C-terminus region Anth_Ig PF05587.8 EMC87352.1 - 1.2e-44 150.4 1.0 1.7e-44 149.9 0.7 1.2 1 0 0 1 1 1 1 Anthrax receptor extracellular domain VWA PF00092.23 EMC87352.1 - 1.9e-17 63.5 0.0 2.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC87352.1 - 2.6e-09 37.4 0.0 4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMC87352.1 - 0.00078 18.6 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF3328 PF11807.3 EMC87352.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3328) zf-C2H2 PF00096.21 EMC87353.1 - 6.7e-05 22.9 30.6 0.016 15.5 4.4 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87353.1 - 0.007 16.6 25.6 0.074 13.4 4.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger SET PF00856.23 EMC87353.1 - 0.011 16.0 0.0 0.011 16.0 0.0 2.5 3 1 0 3 3 3 0 SET domain zf-C2H2_2 PF12756.2 EMC87353.1 - 0.063 13.3 17.2 1.4 9.0 2.0 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 EMC87353.1 - 0.25 10.9 4.3 0.26 10.8 1.6 2.1 2 0 0 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.3 EMC87353.1 - 0.38 10.9 20.3 0.6 10.3 1.3 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Uso1_p115_C PF04871.8 EMC87353.1 - 0.43 10.5 10.6 1 9.2 6.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-met PF12874.2 EMC87353.1 - 4.9 7.5 16.5 0.39 10.9 1.3 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC87353.1 - 7.8 6.5 20.2 0.14 12.0 1.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_S41 PF03572.13 EMC87354.1 - 5.2e-127 419.7 0.0 9e-32 109.8 0.0 4.2 4 0 0 4 4 4 4 Peptidase family S41 DUF3436 PF11918.3 EMC87354.1 - 1.7e-18 66.5 3.8 2.2e-17 63.0 0.1 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3436) muHD PF10291.4 EMC87354.1 - 0.00023 20.4 0.0 2.8 7.0 0.0 4.0 4 1 1 5 5 5 3 Muniscin C-terminal mu homology domain TGF_beta PF00019.15 EMC87355.1 - 1.6e-36 124.7 0.5 3.4e-36 123.6 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC87355.1 - 4.5e-35 121.0 0.1 7.3e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC87356.1 - 4.9e-35 119.9 0.2 1e-34 118.9 0.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Y_phosphatase PF00102.22 EMC87357.1 - 1.5e-75 253.5 0.2 1.9e-75 253.2 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC87357.1 - 6.2e-05 22.6 0.1 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EMC87357.1 - 0.0093 14.7 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.1 EMC87357.1 - 0.029 14.4 0.1 0.052 13.5 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate PDZ PF00595.19 EMC87358.1 - 3.7e-43 145.5 8.2 1.1e-14 54.2 0.5 3.2 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC87358.1 - 1.2e-19 69.9 0.7 1.2e-05 25.1 0.1 3.4 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.1 EMC87358.1 - 0.0089 15.7 0.7 0.94 9.3 0.1 3.2 3 1 0 3 3 3 1 Tricorn protease PDZ domain Pkinase PF00069.20 EMC87359.1 - 5e-66 222.4 0.0 6.3e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87359.1 - 1.2e-29 103.1 0.0 1.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC87359.1 - 5.6e-07 28.8 0.1 8.7e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC87359.1 - 5.1e-05 22.3 0.1 9.1e-05 21.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC87359.1 - 0.00034 20.0 0.2 0.00066 19.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMC87359.1 - 0.00057 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RhoGAP PF00620.22 EMC87360.1 - 3.5e-48 163.0 0.9 5.9e-48 162.3 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain APG6 PF04111.7 EMC87360.1 - 0.013 14.5 9.6 0.023 13.7 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ATG16 PF08614.6 EMC87360.1 - 0.02 14.7 10.6 0.045 13.5 7.3 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PH PF00169.24 EMC87360.1 - 0.045 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 PH domain DUF4337 PF14235.1 EMC87360.1 - 0.05 13.4 2.6 0.097 12.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ADIP PF11559.3 EMC87360.1 - 0.095 12.6 9.1 0.2 11.5 6.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Lzipper-MIP1 PF14389.1 EMC87360.1 - 0.13 12.3 7.9 0.17 12.0 2.7 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 I_LWEQ PF01608.12 EMC87360.1 - 0.36 10.7 8.9 0.27 11.1 4.5 2.0 2 0 0 2 2 2 0 I/LWEQ domain DUF2951 PF11166.3 EMC87360.1 - 0.39 10.5 5.0 0.9 9.4 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) V_ATPase_I PF01496.14 EMC87360.1 - 0.4 8.4 5.4 0.61 7.8 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-18_N PF10496.4 EMC87360.1 - 0.58 10.0 4.9 2.9 7.8 0.5 2.6 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus SPX PF03105.14 EMC87360.1 - 1.2 8.8 13.2 1.6 8.4 9.1 1.4 1 1 0 1 1 1 0 SPX domain Tropomyosin_1 PF12718.2 EMC87360.1 - 2.4 7.9 17.9 7.4 6.4 12.1 1.8 1 1 0 1 1 1 0 Tropomyosin like Beach PF02138.13 EMC87361.1 - 1.2e-104 349.5 0.1 2.3e-104 348.6 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EMC87361.1 - 8.1e-12 44.9 0.1 2e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EMC87361.1 - 5.6e-08 32.3 0.2 5.6e-08 32.3 0.1 5.2 4 1 0 4 4 4 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EMC87361.1 - 0.00084 19.5 0.0 0.0025 18.0 0.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily V-set PF07686.12 EMC87362.1 - 1.6e-08 34.4 0.3 2.8e-08 33.6 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC87362.1 - 2.3e-05 24.1 0.0 6e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC87362.1 - 6.4e-05 23.0 0.1 0.0003 20.8 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Shisa PF13908.1 EMC87362.1 - 0.021 15.0 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Homeobox PF00046.24 EMC87364.1 - 4.4e-25 87.0 5.1 7.2e-25 86.3 3.5 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 EMC87364.1 - 3.1e-07 29.6 1.5 3.1e-07 29.6 1.0 2.0 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.6 EMC87364.1 - 0.029 14.0 0.4 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Homeobox KN domain EspF PF04806.7 EMC87364.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.4 2 0 0 2 2 2 0 EspF protein repeat TP2 PF01254.13 EMC87364.1 - 1.8 8.8 5.9 0.56 10.5 0.3 2.1 2 0 0 2 2 2 0 Nuclear transition protein 2 IL8 PF00048.15 EMC87365.1 - 1.8e-10 40.5 1.1 2.1e-10 40.4 0.8 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like zf-CSL PF05207.8 EMC87365.1 - 0.077 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 CSL zinc finger IL12p40_C PF10420.4 EMC87366.1 - 0.092 12.8 1.1 8 6.6 0.3 2.5 2 1 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus DUF1966 PF09260.6 EMC87366.1 - 0.12 12.4 0.2 6.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) ABC1 PF03109.11 EMC87367.1 - 3e-14 53.0 0.0 4.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 ABC1 family OMPdecase PF00215.19 EMC87369.1 - 2.7e-79 265.7 0.0 4.1e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 EMC87369.1 - 1.8e-12 47.0 0.1 7.5e-12 45.0 0.1 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Integrin_beta PF00362.13 EMC87370.1 - 2.4e-186 619.7 0.0 3.9e-186 619.0 0.0 1.3 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 EMC87370.1 - 5e-19 67.4 0.2 1.1e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 EMC87370.1 - 1.1e-17 64.1 5.6 1.1e-17 64.1 3.9 4.5 4 1 1 5 5 5 1 Integrin beta tail domain EGF_2 PF07974.8 EMC87370.1 - 2.2e-07 30.8 99.1 0.00084 19.4 10.8 6.2 5 1 1 6 6 6 4 EGF-like domain hEGF PF12661.2 EMC87370.1 - 0.059 13.4 0.4 0.057 13.5 0.9 6.1 7 1 0 7 7 7 0 Human growth factor-like EGF EGF PF00008.22 EMC87371.1 - 0.0029 17.5 7.1 0.0029 17.5 4.9 4.8 4 0 0 4 4 4 2 EGF-like domain EphA2_TM PF14575.1 EMC87371.1 - 0.0087 16.4 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EMC87371.1 - 0.047 13.3 0.2 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF1191 PF06697.7 EMC87371.1 - 0.1 11.4 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2189 PF09955.4 EMC87371.1 - 0.92 9.4 4.5 0.29 11.0 0.9 1.7 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) EGF_CA PF07645.10 EMC87372.1 - 2.1e-07 30.8 29.3 2.1e-07 30.8 3.6 3.8 2 1 2 4 4 4 2 Calcium-binding EGF domain EGF PF00008.22 EMC87372.1 - 2.3e-05 24.2 5.6 2.3e-05 24.2 3.9 2.7 2 0 0 2 2 2 1 EGF-like domain EGF_MSP1_1 PF12946.2 EMC87372.1 - 0.00042 20.0 6.5 0.00042 20.0 4.5 3.3 2 1 1 3 3 3 1 MSP1 EGF domain 1 EGF_3 PF12947.2 EMC87372.1 - 0.0023 17.8 20.4 0.0023 17.8 2.5 2.9 3 0 0 3 3 3 2 EGF domain Orthoreo_P10 PF07204.6 EMC87372.1 - 0.027 14.1 0.1 0.074 12.8 0.1 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 hEGF PF12661.2 EMC87372.1 - 0.1 12.7 5.2 4.9 7.4 0.4 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF FXa_inhibition PF14670.1 EMC87372.1 - 0.75 9.9 29.9 0.074 13.1 6.2 3.5 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site EB PF01683.13 EMC87372.1 - 3.2 7.8 25.0 1.6 8.8 5.1 3.2 2 1 1 3 3 3 0 EB module cEGF PF12662.2 EMC87372.1 - 3.6 7.3 21.9 0.87 9.2 0.4 4.4 5 0 0 5 5 5 0 Complement Clr-like EGF-like AA_permease PF00324.16 EMC87373.1 - 4.6e-44 150.5 38.1 4.6e-44 150.5 26.4 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 EMC87373.1 - 4e-19 68.4 36.8 4e-19 68.4 25.5 2.1 2 0 0 2 2 2 1 Amino acid permease YrhC PF14143.1 EMC87373.1 - 0.67 9.9 0.0 0.67 9.9 0.0 3.8 5 0 0 5 5 5 0 YrhC-like protein zf-H2C2_2 PF13465.1 EMC87374.1 - 5.9e-24 83.1 24.5 1e-07 31.8 0.4 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87374.1 - 2.1e-12 46.5 39.5 0.00071 19.7 0.9 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87374.1 - 1.8e-07 30.9 35.6 0.031 14.6 3.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EMC87374.1 - 0.22 11.3 13.4 0.25 11.1 1.9 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 EMC87374.1 - 0.31 10.8 8.1 1.4 8.8 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.3 EMC87374.1 - 1.7 8.8 18.5 4.6 7.5 1.9 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 EMC87374.1 - 7.9 6.0 7.4 26 4.3 0.0 3.3 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 PX PF00787.19 EMC87375.1 - 7.6e-23 80.4 0.1 1.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EMC87375.1 - 3.2e-07 29.8 11.4 0.00055 19.2 3.2 2.2 1 1 1 2 2 2 2 Vps5 C terminal like Pkinase PF00069.20 EMC87376.1 - 3.9e-48 163.8 0.0 5.9e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ecTbetaR2 PF08917.5 EMC87376.1 - 6.2e-39 132.4 13.3 6.2e-39 132.4 9.2 2.0 2 0 0 2 2 2 1 Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr PF07714.12 EMC87376.1 - 6.4e-32 110.6 0.0 1.4e-31 109.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase BLVR PF06375.6 EMC87376.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Choline_kinase PF01633.15 EMC87376.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Oxysterol_BP PF01237.13 EMC87377.1 - 4.2e-47 160.3 7.9 4.1e-31 107.7 0.2 3.0 2 1 0 2 2 2 2 Oxysterol-binding protein PH PF00169.24 EMC87377.1 - 2.5e-12 46.9 0.0 5.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EMC87377.1 - 1e-08 35.1 0.0 3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 EMC87377.1 - 2.6e-05 24.2 0.0 6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EMC87377.1 - 0.0043 17.2 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain NAD_Gly3P_dh_C PF07479.9 EMC87378.1 - 2e-56 189.8 0.1 3.1e-56 189.2 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EMC87378.1 - 4.5e-49 166.1 0.1 1.9e-48 164.1 0.0 2.0 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EMC87378.1 - 0.065 13.6 0.1 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF643 PF04867.7 EMC87378.1 - 0.072 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF643) KH_1 PF00013.24 EMC87378.1 - 0.41 10.3 0.0 0.41 10.3 0.0 3.1 5 0 0 5 5 5 0 KH domain Peptidase_M8 PF01457.11 EMC87379.1 - 2.1e-102 343.1 1.6 2.6e-102 342.8 1.1 1.0 1 0 0 1 1 1 1 Leishmanolysin WWE PF02825.15 EMC87380.1 - 1.1e-06 28.0 0.1 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 WWE domain LSM PF01423.17 EMC87380.1 - 0.1 12.1 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 LSM domain DUF971 PF06155.7 EMC87380.1 - 0.13 12.7 0.1 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Gag_p24 PF00607.15 EMC87381.1 - 0.082 12.4 0.0 1.1 8.7 0.1 2.0 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Macro PF01661.16 EMC87382.1 - 3.8e-65 217.1 0.2 2.7e-31 107.8 0.0 4.1 3 0 0 3 3 3 3 Macro domain PARP PF00644.15 EMC87382.1 - 1.2e-27 96.6 0.6 4.4e-27 94.8 0.4 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WGG PF10273.4 EMC87382.1 - 0.00076 19.5 0.6 0.6 10.2 0.1 3.8 3 0 0 3 3 3 1 Pre-rRNA-processing protein TSR2 WWE PF02825.15 EMC87382.1 - 0.004 16.5 0.9 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 WWE domain RRM_6 PF14259.1 EMC87382.1 - 0.013 15.4 0.1 0.049 13.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ETF_QO PF05187.8 EMC87382.1 - 0.045 13.7 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase zf-RING_2 PF13639.1 EMC87383.1 - 5.3e-09 35.7 7.9 1e-08 34.8 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC87383.1 - 1.7e-08 34.0 8.8 3.8e-08 32.8 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC87383.1 - 6.3e-07 29.3 10.7 6.3e-07 29.3 7.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87383.1 - 8.6e-07 28.5 9.9 1.9e-06 27.5 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC87383.1 - 8.8e-07 28.4 11.4 2e-06 27.3 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC87383.1 - 0.0033 17.5 7.4 0.0095 16.0 5.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC87383.1 - 0.0046 16.7 9.3 0.012 15.4 6.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EMC87383.1 - 0.0062 16.0 6.5 0.024 14.1 4.5 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EMC87383.1 - 0.0066 16.1 3.0 0.014 15.1 2.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMC87383.1 - 0.02 14.6 5.2 0.023 14.4 2.4 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Siva PF05458.7 EMC87383.1 - 0.026 14.0 1.8 0.052 13.1 1.2 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-Nse PF11789.3 EMC87383.1 - 0.054 13.0 6.1 0.15 11.6 4.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EMC87383.1 - 0.054 13.0 9.0 0.13 11.8 6.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EMC87383.1 - 0.69 9.4 8.8 1.3 8.5 6.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EMC87383.1 - 1.1 8.8 8.7 4.1 6.9 6.0 1.9 1 1 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 EMC87383.1 - 6.8 6.5 7.9 21 5.0 5.5 1.8 1 0 0 1 1 1 0 Double zinc ribbon Macro PF01661.16 EMC87384.1 - 9e-41 138.4 0.2 3.5e-30 104.3 0.1 2.8 3 0 0 3 3 3 2 Macro domain PARP PF00644.15 EMC87384.1 - 2.1e-05 24.0 0.1 8.3e-05 22.0 0.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain FAIM1 PF06905.8 EMC87385.1 - 7.1e-93 308.7 3.7 8.2e-93 308.4 2.5 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) 5_nucleotid_C PF02872.13 EMC87385.1 - 0.002 18.1 0.1 0.0059 16.6 0.0 1.7 1 1 0 2 2 2 1 5'-nucleotidase, C-terminal domain DUF365 PF04033.7 EMC87386.1 - 1.8 8.6 6.6 0.26 11.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF365) C2 PF00168.25 EMC87387.1 - 4.8e-47 157.7 0.7 1.2e-18 66.7 0.0 3.5 3 0 0 3 3 3 3 C2 domain PapD-like PF14874.1 EMC87389.1 - 2.9e-05 23.9 0.1 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like 7tm_2 PF00002.19 EMC87390.1 - 4.7e-86 287.8 17.2 5.9e-86 287.4 11.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC87390.1 - 3.2e-19 68.6 4.2 3.2e-19 68.6 2.9 1.8 2 0 0 2 2 2 1 Hormone receptor domain DUF4231 PF14015.1 EMC87390.1 - 0.81 9.6 5.3 7.9 6.5 3.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) TMEM37 PF15108.1 EMC87391.1 - 7.3e-90 299.6 13.4 8.1e-90 299.4 9.3 1.0 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family SK_channel PF03530.9 EMC87391.1 - 0.31 10.8 6.7 0.097 12.5 0.6 2.2 2 1 0 2 2 2 0 Calcium-activated SK potassium channel NVEALA PF14055.1 EMC87391.1 - 1.3 8.8 5.3 5.8 6.7 0.0 3.2 3 0 0 3 3 3 0 NVEALA protein Ninjurin PF04923.7 EMC87391.1 - 2.6 7.8 5.1 13 5.5 3.5 2.2 1 1 0 1 1 1 0 Ninjurin ACBP PF00887.14 EMC87392.1 - 2.9e-33 113.3 2.0 3.1e-33 113.2 1.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 EMC87392.1 - 0.053 13.7 0.2 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 FERM central domain DUF2340 PF10209.4 EMC87393.1 - 7.8e-46 155.2 0.1 8.7e-46 155.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ferric_reduct PF01794.14 EMC87394.1 - 1.2e-19 70.6 5.4 2.3e-16 60.0 1.2 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component F420_oxidored PF03807.12 EMC87394.1 - 3.3e-16 59.5 0.1 2.4e-15 56.7 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMC87394.1 - 6e-05 22.9 0.0 0.0006 19.6 0.0 2.1 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EMC87394.1 - 0.006 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 EMC87394.1 - 0.006 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EMC87394.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF781 PF05612.7 EMC87394.1 - 0.044 12.4 0.2 0.17 10.5 0.0 2.0 2 0 0 2 2 2 0 Mouse protein of unknown function (DUF781) C1q PF00386.16 EMC87395.1 - 1.5e-12 47.5 0.1 1.6e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 EMC87395.1 - 0.0091 15.5 0.0 0.0097 15.4 0.0 1.0 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 EMC87396.1 - 4.9e-40 134.8 127.0 1.1e-09 37.6 19.5 5.3 1 1 4 5 5 5 5 Collagen triple helix repeat (20 copies) SRCR PF00530.13 EMC87396.1 - 1.7e-30 105.2 3.3 3.1e-30 104.4 2.3 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC87396.1 - 4.5e-07 30.0 0.4 1.4e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain MHC2-interact PF09307.5 EMC87396.1 - 0.0024 17.6 0.1 0.0038 16.9 0.1 1.3 1 0 0 1 1 1 1 CLIP, MHC2 interacting Homeobox PF00046.24 EMC87397.1 - 8.3e-23 79.7 8.0 1.1e-22 79.3 5.5 1.2 1 0 0 1 1 1 1 Homeobox domain Engrail_1_C_sig PF10525.4 EMC87397.1 - 4.7e-20 70.3 0.4 6.9e-20 69.8 0.3 1.3 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain DUF2316 PF10078.4 EMC87397.1 - 0.00036 20.4 1.0 0.0004 20.3 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) Homeobox_KN PF05920.6 EMC87397.1 - 0.0016 18.0 1.1 0.0031 17.1 0.6 1.6 1 1 0 1 1 1 1 Homeobox KN domain TPD52 PF04201.10 EMC87397.1 - 0.013 15.1 0.7 0.016 14.9 0.5 1.1 1 0 0 1 1 1 0 Tumour protein D52 family CENP-B_N PF04218.8 EMC87397.1 - 0.016 14.5 0.3 0.016 14.5 0.2 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain QLQ PF08880.6 EMC87397.1 - 0.84 9.0 4.2 0.26 10.7 1.0 1.7 2 1 0 2 2 2 0 QLQ INSIG PF07281.7 EMC87398.1 - 1.2e-56 191.1 0.7 1.4e-56 190.9 0.5 1.0 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) OMP_b-brl PF13505.1 EMC87398.1 - 0.028 14.3 0.1 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain KOG2701 PF09762.4 EMC87399.1 - 5.7e-82 274.1 0.1 5.7e-82 274.1 0.0 3.6 3 1 0 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) DUF4200 PF13863.1 EMC87399.1 - 0.013 15.4 5.5 0.013 15.4 3.8 4.7 3 1 0 4 4 4 0 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EMC87399.1 - 0.019 14.1 1.1 0.04 13.0 0.8 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PMC2NT PF08066.7 EMC87399.1 - 0.084 13.1 7.5 1.1 9.6 0.3 3.6 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Pox_A_type_inc PF04508.7 EMC87399.1 - 0.12 12.2 3.5 2.1 8.3 0.8 3.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.7 EMC87399.1 - 0.71 10.1 5.8 9.6 6.5 3.6 3.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EMC87399.1 - 1 9.1 10.5 2.3 8.0 4.5 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus 7tm_1 PF00001.16 EMC87400.1 - 1.7e-69 233.7 10.2 2.3e-69 233.4 7.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC87400.1 - 0.22 10.6 11.6 0.0073 15.4 3.4 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF3278 PF11683.3 EMC87400.1 - 0.81 9.6 5.1 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF2208 PF09973.4 EMC87400.1 - 0.97 8.6 4.4 22 4.1 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DEAD PF00270.24 EMC87401.1 - 2.3e-45 154.1 0.0 5.1e-45 152.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC87401.1 - 1.4e-21 76.1 0.0 4.5e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMC87401.1 - 9.3e-20 69.9 0.4 1.8e-19 69.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EMC87401.1 - 1.4e-05 24.9 0.6 2.8e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DPPIV_N PF00930.16 EMC87402.1 - 1.8e-110 368.8 0.4 2.7e-110 368.3 0.3 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMC87402.1 - 6.8e-48 162.7 0.0 1e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMC87402.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EMC87402.1 - 2.4e-05 23.8 0.0 0.2 11.3 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.13 EMC87402.1 - 7.7e-05 22.0 0.1 0.00028 20.2 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EMC87402.1 - 0.0011 18.9 0.0 0.016 15.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMC87402.1 - 0.0062 15.9 0.3 0.0062 15.9 0.2 2.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMC87402.1 - 0.017 14.6 0.0 0.26 10.8 0.0 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EMC87402.1 - 0.074 12.4 0.1 3.1 7.1 0.0 2.7 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) DUF384 PF04064.8 EMC87403.1 - 7.4e-23 79.8 2.1 1e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.9 EMC87403.1 - 6e-18 65.0 0.0 1.8e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF383) CNRIP1 PF15043.1 EMC87405.1 - 7.3e-76 252.8 0.1 8.1e-76 252.7 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 PH PF00169.24 EMC87406.1 - 4e-37 126.5 0.0 2.4e-17 63.0 0.0 2.6 3 0 0 3 3 3 2 PH domain DEP PF00610.16 EMC87406.1 - 3e-14 52.5 0.0 5.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_9 PF15410.1 EMC87406.1 - 3.4e-11 43.3 0.2 4.8e-05 23.5 0.0 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 EMC87406.1 - 1.1e-09 38.2 0.0 3.7e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EMC87406.1 - 5.8e-09 36.1 5.6 0.0043 17.2 0.2 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EMC87406.1 - 0.0011 18.9 0.2 0.065 13.3 0.0 3.3 2 2 1 3 3 3 1 Pleckstrin homology domain F-box-like PF12937.2 EMC87407.1 - 1.3e-09 37.6 0.2 1.3e-09 37.6 0.1 2.3 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 EMC87407.1 - 0.00043 19.8 3.9 0.00074 19.1 0.1 2.9 2 1 1 3 3 3 1 F-box domain zf-CCHH PF10283.4 EMC87408.1 - 2.4e-22 78.4 15.2 1e-11 44.4 1.7 2.4 2 0 0 2 2 2 2 Zinc-finger (CX5CX6HX5H) motif HUN PF08729.5 EMC87408.1 - 0.00013 21.7 6.5 0.00033 20.4 4.5 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain 7tm_1 PF00001.16 EMC87409.1 - 1e-47 162.4 23.6 1.3e-47 162.1 16.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87409.1 - 1.7e-05 24.1 27.3 2.4e-05 23.6 18.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Filament PF00038.16 EMC87410.1 - 2.3e-25 89.7 47.3 3.6e-22 79.2 13.6 2.5 3 0 0 3 3 3 2 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMC87410.1 - 0.0074 16.0 12.2 0.0074 16.0 8.5 4.8 4 1 0 4 4 4 1 TPR/MLP1/MLP2-like protein ApoO PF09769.4 EMC87410.1 - 0.042 13.5 1.2 2.4 7.8 0.9 3.2 2 0 0 2 2 2 0 Apolipoprotein O Cut8_M PF14483.1 EMC87410.1 - 0.072 12.9 0.0 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Cut8 dimerisation domain Lectin_N PF03954.9 EMC87410.1 - 0.29 10.5 4.4 0.54 9.6 1.3 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 EMC87410.1 - 0.49 10.2 10.5 0.2 11.4 0.7 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S8 PF00082.17 EMC87411.1 - 3.3e-53 180.6 4.1 4.4e-53 180.2 2.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EMC87411.1 - 3.9e-30 103.4 0.1 8.7e-30 102.3 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain SH3_2 PF07653.12 EMC87412.1 - 1.7e-18 65.8 0.0 2.5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC87412.1 - 7.3e-05 22.2 0.1 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF239 PF03080.10 EMC87412.1 - 0.011 14.7 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF239) RRM_1 PF00076.17 EMC87413.1 - 8.3e-27 92.6 0.5 1.5e-14 53.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC87413.1 - 9.8e-18 63.7 0.3 2.2e-11 43.3 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC87413.1 - 9.3e-15 54.3 0.4 8.2e-07 28.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EMC87413.1 - 4.7e-05 23.0 0.6 0.00092 18.8 0.0 2.5 2 1 0 2 2 2 1 Calcipressin DUF45 PF01863.12 EMC87413.1 - 0.069 12.9 0.4 0.15 11.7 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF45 Kinesin PF00225.18 EMC87414.1 - 5.1e-112 373.8 0.3 5.1e-112 373.8 0.2 3.7 2 1 2 4 4 4 1 Kinesin motor domain PX PF00787.19 EMC87414.1 - 4.8e-16 58.5 1.0 4.8e-16 58.5 0.7 3.4 2 1 1 3 3 3 1 PX domain RecO_N_2 PF13114.1 EMC87414.1 - 0.042 13.5 0.0 0.17 11.5 0.0 2.1 1 0 0 1 1 1 0 RecO N terminal Cytadhesin_P30 PF07271.6 EMC87415.1 - 0.021 14.1 6.0 0.16 11.2 3.7 2.1 1 1 0 1 1 1 0 Cytadhesin P30/P32 Nucleic_acid_bd PF13820.1 EMC87415.1 - 0.11 12.1 5.3 0.1 12.1 0.4 2.1 1 1 1 2 2 2 0 Putative nucleic acid-binding region Serglycin PF04360.7 EMC87415.1 - 0.57 9.9 42.9 2.9e+03 -2.2 8.2 3.3 1 1 1 2 2 2 0 Serglycin RAP1 PF07218.6 EMC87415.1 - 2.3 6.2 7.9 2.9 5.8 5.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TPR_1 PF00515.23 EMC87416.1 - 3.7e-45 149.7 13.2 1e-09 37.5 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EMC87416.1 - 5.4e-42 141.2 16.6 1.4e-12 47.0 1.3 7.5 4 1 4 8 8 8 6 TPR repeat Apc3 PF12895.2 EMC87416.1 - 1.3e-32 111.7 25.8 5e-21 74.6 3.6 5.5 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EMC87416.1 - 5.4e-32 107.1 14.8 6.5e-06 25.6 0.1 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMC87416.1 - 1.1e-29 102.1 7.5 4.5e-08 32.9 0.0 7.2 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87416.1 - 2.5e-26 89.4 6.4 6e-06 25.6 0.2 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87416.1 - 1.3e-23 81.2 9.0 0.014 15.5 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87416.1 - 2.6e-22 78.9 1.6 1.9e-07 31.5 0.0 6.5 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87416.1 - 1.5e-20 73.2 6.4 0.00016 21.9 0.0 7.5 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87416.1 - 1.2e-15 56.6 0.0 0.07 13.8 0.0 8.5 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC87416.1 - 5.7e-14 51.5 10.5 0.015 15.7 0.0 8.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMC87416.1 - 9.3e-09 34.4 2.0 0.23 11.3 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC87416.1 - 2e-08 33.9 0.0 0.021 14.6 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EMC87416.1 - 3.8e-05 22.8 0.1 1.3 7.9 0.0 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.5 EMC87416.1 - 9.6e-05 21.3 1.5 0.065 11.9 0.0 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 EMC87416.1 - 0.0065 16.4 0.0 0.96 9.3 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMC87416.1 - 0.017 15.0 2.2 18 5.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMC87416.1 - 0.022 14.8 0.4 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.4 EMC87416.1 - 7.5 5.9 8.8 1.8 7.9 0.1 3.3 2 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) PEHE PF15275.1 EMC87417.1 - 1.4e-30 106.2 3.0 1.4e-30 106.2 2.1 4.3 4 1 0 4 4 4 1 PEHE domain Tubulin-binding PF00418.14 EMC87418.1 - 1.2e-65 216.8 28.3 3.5e-17 61.7 1.3 5.0 5 0 0 5 5 5 4 Tau and MAP protein, tubulin-binding repeat Mito_carr PF00153.22 EMC87419.1 - 1.4e-44 149.7 0.8 3e-20 71.7 0.0 4.2 4 1 0 4 4 4 4 Mitochondrial carrier protein RIIa PF02197.12 EMC87419.1 - 0.16 11.4 0.9 0.33 10.4 0.6 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit RUN PF02759.14 EMC87420.1 - 7e-28 97.0 0.0 1.9e-27 95.6 0.0 1.7 2 0 0 2 2 2 1 RUN domain HMG_box_5 PF14887.1 EMC87421.1 - 2e-50 168.5 18.7 4.2e-48 161.0 4.0 5.9 5 2 1 6 6 6 3 HMG (high mobility group) box 5 HMG_box PF00505.14 EMC87421.1 - 1.6e-47 159.5 77.0 1.1e-17 63.9 5.2 8.5 7 1 1 8 8 8 5 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC87421.1 - 4.8e-22 78.1 70.8 2.1e-08 34.3 0.1 8.2 8 1 1 9 9 9 5 HMG-box domain GIDA PF01134.17 EMC87421.1 - 8.1 5.1 7.2 1.5 7.5 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF4539 PF15072.1 EMC87422.1 - 1.2e-18 66.5 0.0 1.4e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4539) Glyco_hydro_31 PF01055.21 EMC87423.1 - 2.5e-90 303.4 2.7 2.5e-54 184.7 0.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 MFS_1 PF07690.11 EMC87424.1 - 1.7e-14 53.2 30.4 4e-13 48.8 17.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC87424.1 - 3.4e-10 38.9 1.6 3.4e-10 38.9 1.1 3.2 4 0 0 4 4 4 2 MFS/sugar transport protein FAM220 PF15487.1 EMC87424.1 - 0.23 10.7 2.0 0.35 10.2 1.4 1.1 1 0 0 1 1 1 0 FAM220 family zf-C2H2 PF00096.21 EMC87425.1 - 1.5e-14 53.3 20.1 2e-05 24.6 0.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC87425.1 - 3.8e-12 45.8 18.5 2.8e-07 30.5 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC87425.1 - 1.4e-09 37.6 19.6 0.006 16.8 0.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC87425.1 - 0.0011 18.7 2.0 0.83 9.6 0.0 3.1 3 1 0 3 3 3 2 C2H2-type zinc finger Ogr_Delta PF04606.7 EMC87425.1 - 0.034 13.7 1.7 0.32 10.6 0.1 2.7 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-met PF12874.2 EMC87425.1 - 0.047 13.9 8.8 0.14 12.4 0.9 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.16 EMC87425.1 - 0.53 10.1 4.3 3.6 7.5 3.0 2.3 1 1 0 1 1 1 0 IBR domain zf-CGNR PF11706.3 EMC87425.1 - 3.8 7.0 6.7 17 5.0 0.1 2.6 2 1 0 2 2 2 0 CGNR zinc finger zf-C2H2_jaz PF12171.3 EMC87425.1 - 7.4 6.8 9.8 19 5.5 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ets PF00178.17 EMC87426.1 - 5.9e-38 128.8 2.0 9e-38 128.2 1.4 1.3 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 EMC87426.1 - 0.1 12.7 1.4 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 HSF-type DNA-binding MFS_1 PF07690.11 EMC87427.1 - 8.3e-09 34.6 42.3 8.5e-05 21.4 19.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GLTT PF01744.15 EMC87428.1 - 4.9e-19 67.2 8.0 0.00035 19.9 0.0 5.5 3 2 4 7 7 7 6 GLTT repeat (6 copies) Pentapeptide_2 PF01469.13 EMC87428.1 - 1.6e-07 30.8 7.0 0.0045 16.5 0.1 3.6 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Lamprin PF06403.6 EMC87428.1 - 0.0014 18.3 16.2 3.3e+02 0.9 11.3 3.0 1 1 0 1 1 1 0 Lamprin DUF2960 PF11173.3 EMC87428.1 - 0.29 11.4 12.1 5.8 7.2 1.2 5.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2960) Kelch_1 PF01344.20 EMC87429.1 - 6.6e-45 150.4 0.0 2.2e-08 33.5 0.0 7.1 7 0 0 7 7 7 7 Kelch motif Kelch_6 PF13964.1 EMC87429.1 - 9.6e-37 123.6 0.9 5.7e-08 32.6 0.0 7.1 3 3 4 7 7 7 7 Kelch motif Kelch_3 PF13415.1 EMC87429.1 - 4.1e-21 74.5 0.0 2.4e-05 24.3 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC87429.1 - 1.9e-20 72.3 0.5 3.7e-06 26.6 0.0 6.4 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC87429.1 - 3e-18 64.8 0.1 4e-05 23.2 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMC87429.1 - 1.7e-05 24.6 0.8 10 6.1 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Pkinase PF00069.20 EMC87430.1 - 1.6e-78 263.4 0.1 2.2e-78 262.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87430.1 - 1e-43 149.2 0.0 1.5e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87430.1 - 6.2e-07 28.6 0.0 9.6e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC87430.1 - 3.8e-06 26.3 0.5 6.6e-06 25.5 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMC87430.1 - 3.5e-05 22.9 0.3 5.8e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC87430.1 - 0.006 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tmemb_cc2 PF10267.4 EMC87431.1 - 2.5e-191 635.4 9.0 3.9e-191 634.8 6.2 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein ABC2_membrane_3 PF12698.2 EMC87431.1 - 0.0049 15.9 0.6 0.014 14.4 0.1 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF1479 PF07350.7 EMC87431.1 - 0.014 13.9 4.4 0.035 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) DUF2313 PF10076.4 EMC87431.1 - 0.014 14.7 1.0 0.025 14.0 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) Lipoprotein_20 PF13942.1 EMC87431.1 - 0.65 9.5 16.8 1.3 8.5 1.1 2.5 2 1 0 2 2 2 0 YfhG lipoprotein Baculo_PEP_C PF04513.7 EMC87431.1 - 0.84 9.4 13.7 0.044 13.6 1.0 3.5 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 EMC87431.1 - 1.8 6.0 19.5 0.13 9.8 7.0 2.6 2 1 0 2 2 2 0 Prominin DUF3584 PF12128.3 EMC87431.1 - 8.8 3.5 29.8 0.86 6.8 9.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF2207 PF09972.4 EMC87431.1 - 9.1 4.7 8.2 0.53 8.8 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Archease PF01951.11 EMC87432.1 - 0.01 15.7 0.7 0.051 13.5 0.0 2.3 2 1 1 3 3 3 0 Archease protein family (MTH1598/TM1083) Pkinase PF00069.20 EMC87433.1 - 1.3e-43 149.0 0.0 1.7e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87433.1 - 9.1e-37 126.5 0.0 1.2e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87433.1 - 4.5e-05 22.5 0.0 7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC87433.1 - 0.0008 18.5 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC87433.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.8 2 1 2 4 4 4 0 Phosphotransferase enzyme family WD40 PF00400.27 EMC87434.1 - 4.3e-15 54.9 23.2 4e-07 29.6 1.8 6.7 7 1 0 7 7 7 5 WD domain, G-beta repeat DUF3312 PF11768.3 EMC87434.1 - 0.097 10.8 0.1 0.15 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) ig PF00047.20 EMC87435.1 - 0.00039 20.4 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC87435.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC87435.1 - 0.01 15.6 0.1 0.057 13.3 0.0 2.2 2 1 0 2 2 2 0 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC87435.1 - 0.037 14.5 0.8 0.071 13.6 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain TSP_1 PF00090.14 EMC87435.1 - 0.21 11.7 5.0 0.41 10.8 3.4 1.4 1 0 0 1 1 1 0 Thrombospondin type 1 domain I-set PF07679.11 EMC87436.1 - 4.6e-72 237.9 0.0 2.5e-13 49.6 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC87436.1 - 5.7e-52 173.7 0.0 9.8e-11 41.6 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 EMC87436.1 - 2.3e-43 146.4 0.0 1.7e-06 28.4 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 EMC87436.1 - 3.4e-38 129.6 31.7 3.8e-12 46.1 0.0 6.1 6 0 0 6 6 6 5 Fibronectin type III domain ig PF00047.20 EMC87436.1 - 2.1e-29 101.4 8.5 5.2e-08 32.9 0.0 8.5 9 0 0 9 9 9 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 EMC87436.1 - 8.9e-26 90.6 8.1 2.1e-25 89.4 5.6 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 EMC87436.1 - 6.7e-13 48.5 11.7 0.0021 17.9 0.0 7.7 6 5 1 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC87436.1 - 3.4e-08 33.2 16.6 0.075 12.9 0.0 7.6 8 0 0 8 8 8 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 EMC87436.1 - 1.6e-05 24.7 0.3 0.084 12.8 0.0 4.7 6 0 0 6 6 6 1 Penicillin-Binding Protein C-terminus Family Frag1 PF10277.4 EMC87437.1 - 2e-45 154.9 18.3 2.4e-45 154.6 12.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1301 PF06979.7 EMC87437.1 - 0.31 11.2 2.8 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1301) Bac_export_2 PF01312.14 EMC87437.1 - 0.73 8.6 6.3 0.68 8.7 3.4 1.7 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DUF3989 PF13150.1 EMC87437.1 - 9.9 5.7 7.9 4 6.9 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) CDP-OH_P_transf PF01066.16 EMC87438.1 - 1.5e-22 79.7 3.0 2.2e-22 79.2 2.1 1.3 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase TLV_coat PF00429.14 EMC87438.1 - 0.086 11.2 0.2 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Cation_efflux PF01545.16 EMC87438.1 - 0.087 11.8 0.1 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family DUF606 PF04657.8 EMC87438.1 - 0.38 10.8 3.1 1.1 9.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF606 Spore_YabQ PF09578.5 EMC87438.1 - 0.71 9.8 5.3 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF4131 PF13567.1 EMC87438.1 - 2 7.7 6.8 2.9 7.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DENN PF02141.16 EMC87439.1 - 2.9e-56 190.1 2.5 5.2e-56 189.2 1.8 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EMC87439.1 - 7.7e-26 89.8 0.1 1.5e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EMC87439.1 - 7.7e-20 70.7 1.3 1.4e-19 69.9 0.9 1.4 1 0 0 1 1 1 1 dDENN domain HPD PF05044.7 EMC87439.1 - 0.028 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Homeo-prospero domain Basic PF01586.11 EMC87440.1 - 3.5e-28 98.1 0.2 1e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 Myogenic Basic domain Glyco_transf_54 PF04666.8 EMC87441.1 - 9.6e-95 316.7 0.0 1.3e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Tmemb_9 PF05434.6 EMC87442.1 - 1.3e-49 167.8 8.8 1.9e-27 95.8 1.3 2.1 2 0 0 2 2 2 2 TMEM9 fn3 PF00041.16 EMC87443.1 - 2.1e-59 197.5 8.1 8.7e-15 54.6 0.0 4.6 4 0 0 4 4 4 4 Fibronectin type III domain I-set PF07679.11 EMC87443.1 - 1.4e-55 185.1 0.1 6.5e-18 64.3 0.0 6.5 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC87443.1 - 3.1e-18 65.6 0.0 2.8e-06 27.3 0.1 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Tissue_fac PF01108.12 EMC87443.1 - 2.4e-11 43.3 0.2 0.0026 17.4 0.0 4.3 4 0 0 4 4 4 3 Tissue factor ig PF00047.20 EMC87443.1 - 1.7e-09 37.6 0.9 0.024 14.7 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin domain Receptor_2B4 PF11465.3 EMC87443.1 - 3.5e-08 33.3 0.1 0.0018 18.1 0.0 3.9 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 V-set PF07686.12 EMC87443.1 - 2.3e-06 27.4 3.5 0.055 13.3 0.0 5.5 5 2 1 6 6 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC87443.1 - 8.5e-06 25.5 0.0 0.027 14.3 0.0 3.9 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 EMC87443.1 - 3e-05 24.4 1.8 0.089 13.3 0.1 5.0 5 1 1 6 6 4 1 Immunoglobulin domain Y_Y_Y PF07495.8 EMC87443.1 - 0.0047 16.6 1.3 0.52 10.1 0.1 4.2 4 1 1 5 5 4 1 Y_Y_Y domain DUF2369 PF10179.4 EMC87443.1 - 0.0047 16.0 0.0 2 7.4 0.0 3.1 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) Reeler PF02014.11 EMC87443.1 - 0.0084 16.3 0.5 1.9 8.7 0.0 4.0 4 0 0 4 4 4 1 Reeler domain A2M_N PF01835.14 EMC87443.1 - 0.011 15.9 0.1 3.2 8.0 0.0 3.7 4 0 0 4 4 3 0 MG2 domain SusE PF14292.1 EMC87443.1 - 0.014 15.2 1.7 2.4 8.0 0.1 4.0 4 0 0 4 4 4 0 SusE outer membrane protein FixG_C PF11614.3 EMC87443.1 - 0.1 12.7 0.1 4.6 7.3 0.0 3.3 3 0 0 3 3 3 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PhoD PF09423.5 EMC87443.1 - 0.13 10.7 0.9 2.1 6.8 0.0 2.7 3 1 0 3 3 3 0 PhoD-like phosphatase Arm PF00514.18 EMC87444.1 - 7.9e-30 101.6 6.7 6.6e-10 38.4 0.0 7.7 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC87444.1 - 4.5e-07 30.0 0.7 0.0018 18.5 0.0 3.1 2 2 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EMC87444.1 - 0.00012 22.4 1.2 0.45 11.0 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 EMC87444.1 - 0.00053 19.8 0.2 0.7 10.1 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 EMC87444.1 - 0.024 12.9 1.0 4.4 5.5 0.0 2.5 1 1 0 2 2 2 0 Adaptin N terminal region Mo25 PF08569.6 EMC87444.1 - 0.092 11.7 0.0 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Mo25-like DUF383 PF04063.9 EMC87444.1 - 0.093 12.2 0.5 5.7 6.4 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF383) Arm_2 PF04826.8 EMC87444.1 - 0.1 11.7 1.3 0.83 8.7 0.1 2.6 2 1 1 3 3 3 0 Armadillo-like Troponin PF00992.15 EMC87445.1 - 1.3e-42 145.0 39.3 6.6e-40 136.2 20.9 2.0 1 1 1 2 2 2 2 Troponin PLRV_ORF5 PF01690.12 EMC87445.1 - 3.8 6.5 13.2 4.4 6.3 9.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NBP1 PF08537.5 EMC87445.1 - 8.2 5.5 29.0 0.84 8.7 11.2 2.3 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 Caldesmon PF02029.10 EMC87447.1 - 1.5e-06 26.8 0.2 1.5e-06 26.8 0.1 1.0 1 0 0 1 1 1 1 Caldesmon Troponin PF00992.15 EMC87448.1 - 2e-51 173.4 8.4 2.9e-51 172.9 5.8 1.2 1 0 0 1 1 1 1 Troponin ADIP PF11559.3 EMC87448.1 - 0.065 13.1 2.6 0.16 11.8 1.2 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding XkdW PF09636.5 EMC87448.1 - 0.067 13.0 2.5 0.47 10.3 1.7 2.2 1 1 0 1 1 1 0 XkdW protein IFT20 PF14931.1 EMC87448.1 - 0.069 13.0 5.4 0.49 10.2 0.3 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 TMF_TATA_bd PF12325.3 EMC87448.1 - 3.2 7.5 10.0 4.7 6.9 4.5 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Med9 PF07544.8 EMC87448.1 - 4.2 7.1 6.5 15 5.3 0.6 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PH PF00169.24 EMC87449.1 - 1.4e-05 25.2 0.0 1.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 PH domain FAM194 PF14977.1 EMC87449.1 - 0.013 14.4 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 FAM194 protein LIM PF00412.17 EMC87450.1 - 6.6e-30 102.9 24.8 5.6e-17 61.5 3.7 2.1 2 0 0 2 2 2 2 LIM domain DZR PF12773.2 EMC87450.1 - 0.45 10.3 22.5 0.19 11.5 3.9 3.9 2 2 1 3 3 3 0 Double zinc ribbon zf-DNA_Pol PF08996.5 EMC87450.1 - 0.49 9.7 10.7 0.58 9.4 0.4 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-NADH-PPase PF09297.6 EMC87450.1 - 4 7.0 9.0 5.1 6.7 0.2 3.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain FAST_1 PF06743.10 EMC87451.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Ank PF00023.25 EMC87452.1 - 1.2e-30 103.7 7.2 4.2e-09 35.7 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMC87452.1 - 1.8e-30 105.0 1.6 2e-14 53.6 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC87452.1 - 6.3e-27 93.4 1.4 9.5e-13 48.2 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC87452.1 - 5.5e-24 83.6 3.6 1.9e-10 40.6 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC87452.1 - 1.1e-19 68.5 3.2 2.2e-05 24.2 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat DUF342 PF03961.8 EMC87452.1 - 0.001 17.5 5.8 0.001 17.5 4.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF342) C2 PF00168.25 EMC87453.1 - 3.2e-54 180.7 0.5 1.4e-26 92.1 0.1 2.3 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 EMC87453.1 - 0.00016 21.3 0.4 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 EMC87453.1 - 0.00016 21.2 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 CEP76 C2 domain UPF0561 PF10573.4 EMC87453.1 - 0.0094 15.7 0.1 4.3 7.2 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised protein family UPF0561 EphA2_TM PF14575.1 EMC87453.1 - 0.054 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.1 EMC87453.1 - 0.097 12.3 0.6 0.17 11.5 0.4 1.4 1 0 0 1 1 1 0 FAM176 family TMEM52 PF14979.1 EMC87453.1 - 0.21 11.5 4.2 0.38 10.6 2.9 1.3 1 0 0 1 1 1 0 Transmembrane 52 Prothymosin PF03247.9 EMC87453.1 - 3.7 7.7 15.0 0.61 10.2 5.8 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family Trypan_PARP PF05887.6 EMC87454.1 - 0.37 10.5 13.8 0.93 9.3 9.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Peptidase_M1 PF01433.15 EMC87455.1 - 7.2e-68 229.4 0.0 9.3e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EMC87455.1 - 1.7e-41 141.1 0.6 2.5e-41 140.6 0.4 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EMC87455.1 - 4.8e-19 68.6 0.1 1.4e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase MA superfamily IBN_N PF03810.14 EMC87456.1 - 6.9e-07 29.0 0.0 3.6e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMC87456.1 - 0.00039 20.3 6.0 0.0024 17.7 0.0 4.2 5 0 0 5 5 5 1 Exportin 1-like protein RIX1 PF08167.7 EMC87456.1 - 0.0069 16.0 4.3 0.28 10.8 0.2 3.2 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis HisG_C PF08029.6 EMC87456.1 - 0.01 15.7 0.1 12 5.9 0.0 3.7 3 0 0 3 3 3 0 HisG, C-terminal domain HEAT_EZ PF13513.1 EMC87456.1 - 0.46 11.0 5.9 6.8 7.3 0.0 5.4 4 1 1 5 5 5 0 HEAT-like repeat PLU-1 PF08429.6 EMC87457.1 - 2.6e-98 329.0 14.6 1.3e-93 313.5 2.4 3.4 3 0 0 3 3 3 3 PLU-1-like protein JmjC PF02373.17 EMC87457.1 - 2.1e-44 150.3 0.7 4.5e-44 149.3 0.5 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EMC87457.1 - 1.3e-27 95.1 32.9 2.6e-11 43.0 2.8 4.2 3 0 0 3 3 3 3 PHD-finger ARID PF01388.16 EMC87457.1 - 1.5e-24 85.6 0.0 4.6e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EMC87457.1 - 1e-17 63.9 12.1 1e-17 63.9 8.4 2.9 2 0 0 2 2 2 1 C5HC2 zinc finger PHD_2 PF13831.1 EMC87457.1 - 6.4e-05 22.1 22.8 0.17 11.2 3.5 4.0 3 0 0 3 3 3 3 PHD-finger Kelch_1 PF01344.20 EMC87458.1 - 1.5e-69 229.3 15.5 1.1e-14 53.6 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC87458.1 - 4.3e-40 134.2 13.4 2.2e-09 37.0 0.0 6.2 2 2 4 6 6 6 6 Kelch motif BACK PF07707.10 EMC87458.1 - 1.5e-34 117.8 0.7 3.1e-34 116.8 0.5 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 EMC87458.1 - 7e-28 96.1 10.3 1.3e-08 34.7 0.4 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC87458.1 - 3.7e-27 93.8 13.8 9e-05 22.1 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC87458.1 - 1.6e-25 87.7 6.1 0.0013 18.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EMC87458.1 - 4.6e-14 52.0 10.0 0.022 14.7 0.1 6.2 6 0 0 6 6 6 4 Kelch motif BTB PF00651.26 EMC87458.1 - 7.1e-12 45.2 0.7 1.4e-11 44.3 0.1 1.8 2 1 1 3 3 3 1 BTB/POZ domain HARP PF07443.8 EMC87458.1 - 0.17 11.2 0.9 1.6 8.2 0.0 2.7 3 0 0 3 3 3 0 HepA-related protein (HARP) LRR_8 PF13855.1 EMC87459.1 - 1.9e-82 270.9 49.1 7.1e-15 54.5 0.8 9.0 2 2 8 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 EMC87459.1 - 1.1e-44 149.3 28.1 2.3e-09 36.6 0.0 9.8 3 2 7 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC87459.1 - 3.8e-32 105.3 32.1 0.016 15.1 0.0 16.2 16 1 1 17 17 17 10 Leucine Rich Repeat LRR_5 PF13306.1 EMC87459.1 - 6.6e-27 93.7 0.0 2e-08 33.9 0.0 4.0 1 1 4 5 5 5 5 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC87459.1 - 8.9e-18 62.3 25.6 0.88 9.8 0.0 14.4 13 2 1 14 14 14 5 Leucine Rich repeat LRR_7 PF13504.1 EMC87459.1 - 1.3e-15 54.6 33.6 0.15 12.4 0.0 14.3 15 0 0 15 15 15 5 Leucine rich repeat LRR_9 PF14580.1 EMC87459.1 - 1.5e-10 40.8 3.9 0.02 14.4 0.2 5.2 1 1 3 5 5 5 4 Leucine-rich repeat 7tm_1 PF00001.16 EMC87459.1 - 1.7e-07 30.6 13.7 0.0017 17.5 4.8 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) LRRNT PF01462.13 EMC87459.1 - 1.1e-05 24.7 1.9 3.3e-05 23.2 1.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Y_phosphatase PF00102.22 EMC87460.1 - 1.5e-72 243.7 0.0 1.9e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC87460.1 - 0.00013 21.5 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC87460.1 - 0.0019 18.4 0.2 0.0044 17.2 0.1 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC87460.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Arf PF00025.16 EMC87461.1 - 4.2e-39 133.5 0.1 5e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC87461.1 - 2.7e-14 52.8 0.0 3e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC87461.1 - 9.9e-07 29.2 0.0 4.6e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EMC87461.1 - 1.7e-06 27.3 0.0 1.9e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC87461.1 - 1.6e-05 23.7 0.0 2.4e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 EMC87461.1 - 0.00019 20.9 0.0 0.00022 20.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC87461.1 - 0.00068 18.8 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit 7tm_1 PF00001.16 EMC87462.1 - 1.1e-19 70.6 11.5 1.3e-19 70.3 8.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PDR_CDR PF06422.7 EMC87462.1 - 0.02 14.5 0.9 0.052 13.2 0.1 2.0 2 0 0 2 2 2 0 CDR ABC transporter Rab15_effector PF15208.1 EMC87462.1 - 0.04 13.3 0.2 0.059 12.8 0.2 1.2 1 0 0 1 1 1 0 Rab15 effector Ets PF00178.17 EMC87463.1 - 3.9e-29 100.6 2.0 6.7e-29 99.8 1.4 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 EMC87463.1 - 1.3e-17 63.3 0.1 5e-17 61.4 0.0 2.0 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain EF1G PF00647.14 EMC87463.1 - 0.076 12.7 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain AT_hook PF02178.14 EMC87463.1 - 0.14 11.8 5.2 0.33 10.7 3.6 1.7 1 0 0 1 1 1 0 AT hook motif Lys PF00062.15 EMC87465.1 - 1.7e-52 176.6 2.4 1.9e-52 176.4 1.7 1.0 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.15 EMC87465.1 - 8.5e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Destabilase PF05497.7 EMC87465.1 - 0.0006 19.8 2.5 0.00094 19.2 1.7 1.3 1 0 0 1 1 1 1 Destabilase Transglycosylas PF06737.9 EMC87465.1 - 0.014 15.7 0.3 0.036 14.3 0.2 1.7 1 1 0 1 1 1 0 Transglycosylase-like domain 7tm_4 PF13853.1 EMC87466.1 - 2.4e-60 202.5 10.6 2.4e-60 202.5 7.3 1.8 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC87466.1 - 9.3e-34 116.7 13.2 1.4e-33 116.1 9.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87466.1 - 8.3e-05 21.8 11.8 0.00016 20.9 8.2 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Baculo_11_kDa PF06143.6 EMC87466.1 - 0.023 14.0 2.1 0.063 12.6 1.5 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family FlaG PF03646.10 EMC87468.1 - 0.057 13.5 0.8 0.057 13.5 0.5 6.3 4 3 0 4 4 4 0 FlaG protein DCX PF03607.12 EMC87469.1 - 6.5e-32 108.9 0.0 2.3e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 Doublecortin Sox_C_TAD PF12067.3 EMC87470.1 - 3.4e-39 135.0 13.5 6.2e-39 134.2 9.4 1.4 1 0 0 1 1 1 1 Sox C-terminal transactivation domain G-patch PF01585.18 EMC87470.1 - 3.1e-16 58.8 3.8 5.2e-16 58.1 2.7 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC87470.1 - 3.1e-09 36.5 1.7 8.4e-09 35.1 1.2 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site HMG_box PF00505.14 EMC87470.1 - 2.1e-06 27.8 3.2 4.3e-06 26.9 2.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC87470.1 - 0.013 15.8 1.1 0.032 14.6 0.7 1.7 1 1 0 1 1 1 0 HMG-box domain XK-related PF09815.4 EMC87472.1 - 1.8e-105 352.6 19.9 2.1e-105 352.3 13.8 1.1 1 0 0 1 1 1 1 XK-related protein Meleagrin PF08189.6 EMC87474.1 - 4.8e-14 51.5 17.6 7.1e-14 51.0 12.2 1.3 1 1 0 1 1 1 1 Meleagrin/Cygnin family Nodulin_late PF07127.6 EMC87474.1 - 5 7.3 8.9 1.5e+02 2.5 6.5 2.3 1 1 1 2 2 2 0 Late nodulin protein DUF2116 PF09889.4 EMC87474.1 - 6.3 6.6 7.1 9.3 6.1 1.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Meleagrin PF08189.6 EMC87475.1 - 2.2e-07 30.2 8.5 3.2e-07 29.7 5.9 1.3 1 0 0 1 1 1 1 Meleagrin/Cygnin family Meleagrin PF08189.6 EMC87476.1 - 1.8e-12 46.5 13.8 2.4e-12 46.1 9.6 1.2 1 0 0 1 1 1 1 Meleagrin/Cygnin family Nodulin_late PF07127.6 EMC87476.1 - 0.074 13.1 6.5 2.6 8.2 4.7 2.2 1 1 1 2 2 2 0 Late nodulin protein Myotub-related PF06602.9 EMC87477.1 - 1.2e-130 435.3 1.1 1.6e-130 435.0 0.8 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 EMC87477.1 - 0.0016 17.8 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Hydrolase_6 PF13344.1 EMC87477.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Epimerase PF01370.16 EMC87478.1 - 1.2e-20 73.9 0.0 8.1e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMC87478.1 - 7e-08 31.7 0.0 1.6e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EMC87478.1 - 8.3e-08 31.4 0.0 1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMC87478.1 - 7.1e-07 28.1 0.0 1.1e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC87478.1 - 0.00075 18.4 0.0 0.0091 14.9 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMC87478.1 - 0.0019 18.1 0.2 0.0041 17.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMC87478.1 - 0.019 14.6 0.1 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 KR domain DUF3259 PF11652.3 EMC87479.1 - 2.3e-47 159.0 2.5 4.3e-47 158.1 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3259) LURAP PF14854.1 EMC87479.1 - 0.0014 18.3 0.4 0.0035 17.0 0.1 1.8 2 0 0 2 2 2 1 Leucine rich adaptor protein Dapper PF15268.1 EMC87479.1 - 0.057 12.2 2.7 0.05 12.4 1.0 1.3 1 1 0 1 1 1 0 Dapper DUF2388 PF09498.5 EMC87479.1 - 0.12 11.9 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) IncA PF04156.9 EMC87479.1 - 0.25 10.9 4.9 0.67 9.5 3.3 1.8 1 1 0 1 1 1 0 IncA protein DUF4530 PF15039.1 EMC87479.1 - 1 9.3 4.1 0.28 11.1 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) Pkinase_Tyr PF07714.12 EMC87480.1 - 9.2e-95 316.6 0.0 1.2e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC87480.1 - 1.1e-48 165.6 0.0 1.6e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC87480.1 - 3e-27 94.2 0.1 5.5e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 EMC87480.1 - 3.1e-15 55.2 0.0 7.1e-15 54.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC87480.1 - 1e-11 44.2 0.0 2.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC87480.1 - 4.4e-08 32.4 0.0 1.1e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SusD-like_3 PF14322.1 EMC87480.1 - 0.0095 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Starch-binding associating with outer membrane SH3_3 PF08239.6 EMC87480.1 - 0.013 15.6 0.2 0.041 14.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain SRCR PF00530.13 EMC87481.1 - 6.3e-125 408.1 60.2 2.6e-29 101.4 4.9 5.2 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC87481.1 - 7.8e-16 58.1 21.7 0.002 18.3 1.1 5.5 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain Yeast_MT PF11403.3 EMC87481.1 - 0.037 14.1 8.6 2.4 8.3 0.7 3.6 2 0 0 2 2 2 0 Yeast metallothionein VWD PF00094.20 EMC87482.1 - 1.4e-32 113.0 3.0 1.4e-32 113.0 2.1 2.6 3 0 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.6 EMC87482.1 - 7e-16 58.2 1.7 7e-16 58.2 1.2 4.6 3 1 0 3 3 3 1 C8 domain VWC PF00093.13 EMC87482.1 - 0.00096 19.2 15.1 0.00096 19.2 10.4 8.4 6 2 1 7 7 7 4 von Willebrand factor type C domain VWD PF00094.20 EMC87483.1 - 9.1e-106 350.9 37.3 2.9e-30 105.5 3.1 5.2 5 0 0 5 5 5 4 von Willebrand factor type D domain C8 PF08742.6 EMC87483.1 - 9.8e-61 201.9 56.2 2e-21 76.0 7.2 9.4 10 3 1 11 11 11 4 C8 domain TIL PF01826.12 EMC87483.1 - 1.3e-18 66.7 54.8 1.6e-12 47.3 10.8 18.3 16 3 3 19 19 19 5 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 EMC87483.1 - 1.5e-08 34.5 45.4 1.3e-05 25.1 4.7 17.8 15 6 3 18 18 18 7 von Willebrand factor type C domain uDENN PF03456.13 EMC87485.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 uDENN domain DENN PF02141.16 EMC87485.1 - 0.037 13.7 0.1 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 DENN (AEX-3) domain PKD_channel PF08016.7 EMC87486.1 - 1.1e-06 27.3 11.8 1.3e-06 27.1 8.2 1.0 1 0 0 1 1 1 1 Polycystin cation channel LRR_6 PF13516.1 EMC87488.1 - 1.2e-14 52.6 24.6 0.14 12.2 0.0 10.7 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 EMC87488.1 - 1.7e-11 43.4 24.1 0.016 14.8 1.3 7.1 5 2 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC87488.1 - 7.4e-05 22.2 14.8 17 5.9 0.1 9.8 10 2 1 11 11 11 2 Leucine Rich Repeat HEAT_2 PF13646.1 EMC87489.1 - 1.5e-05 25.1 3.2 9e-05 22.6 0.2 2.8 1 1 1 2 2 2 1 HEAT repeats Arm PF00514.18 EMC87489.1 - 0.0017 18.0 3.7 0.53 10.1 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EMC87489.1 - 0.078 13.1 0.1 0.59 10.3 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 EMC87489.1 - 0.85 10.1 3.0 70 4.1 0.2 3.9 3 1 0 3 3 3 0 HEAT-like repeat Geminin PF07412.7 EMC87490.1 - 1.6e-82 276.1 13.6 1.7e-82 275.9 9.4 1.0 1 0 0 1 1 1 1 Geminin Laminin_II PF06009.7 EMC87490.1 - 0.0088 15.7 2.7 0.0088 15.7 1.9 1.9 2 0 0 2 2 2 1 Laminin Domain II DivIC PF04977.10 EMC87490.1 - 0.01 15.3 0.9 0.01 15.3 0.6 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF342 PF03961.8 EMC87490.1 - 0.049 12.0 5.0 0.057 11.8 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3688 PF12461.3 EMC87490.1 - 0.091 13.1 1.1 0.11 12.8 0.4 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3688) Snapin_Pallidin PF14712.1 EMC87490.1 - 0.33 11.2 4.8 0.077 13.3 0.9 1.8 2 0 0 2 2 2 0 Snapin/Pallidin DUF1342 PF07072.6 EMC87490.1 - 0.54 9.8 5.7 0.98 9.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) Fzo_mitofusin PF04799.8 EMC87490.1 - 0.65 9.3 4.0 0.93 8.8 2.1 1.7 1 1 1 2 2 2 0 fzo-like conserved region NYD-SP28_assoc PF14775.1 EMC87490.1 - 0.68 9.6 4.2 3.9 7.2 2.9 2.3 1 1 0 1 1 1 0 Sperm tail C-terminal domain Spc42p PF11544.3 EMC87490.1 - 0.98 9.3 10.8 0.75 9.7 0.3 3.0 3 0 0 3 3 3 0 Spindle pole body component Spc42p FAR1 PF03101.10 EMC87490.1 - 1.2 9.7 5.8 2.5 8.6 2.7 2.2 1 1 1 2 2 2 0 FAR1 DNA-binding domain DUF641 PF04859.7 EMC87490.1 - 1.3 8.7 8.0 0.19 11.4 2.0 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PhoU PF01895.14 EMC87490.1 - 5.5 7.5 6.7 2.9 8.3 2.1 2.1 1 1 1 2 2 2 0 PhoU domain CCDC-167 PF15188.1 EMC87490.1 - 5.7 6.9 15.0 1.4 8.8 7.3 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4566 PF15130.1 EMC87491.1 - 5.9e-148 490.5 2.1 6.6e-148 490.3 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) 4HBT PF03061.17 EMC87492.1 - 7.1e-14 51.6 0.1 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EMC87492.1 - 3.6e-05 23.6 0.1 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 EMC87492.1 - 0.0019 18.1 0.1 0.0038 17.1 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) Exo_endo_phos PF03372.18 EMC87493.1 - 4.8e-16 59.4 0.0 5.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DOMON PF03351.12 EMC87493.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 DOMON domain 7tm_1 PF00001.16 EMC87494.1 - 1.8e-61 207.5 16.3 2.2e-61 207.2 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC87494.1 - 1e-05 24.8 15.1 0.00063 18.9 10.5 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 EMC87494.1 - 0.00016 20.9 12.3 0.00021 20.5 8.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srd PF10317.4 EMC87494.1 - 0.00024 20.2 21.0 0.022 13.7 14.5 2.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Bac_rhodopsin PF01036.13 EMC87494.1 - 0.83 8.9 13.9 0.051 12.8 4.5 2.2 2 1 0 2 2 2 0 Bacteriorhodopsin-like protein Myelin_MBP PF01669.12 EMC87495.1 - 4e-47 159.5 3.3 6.7e-47 158.7 2.3 1.3 1 0 0 1 1 1 1 Myelin basic protein zf-H2C2_2 PF13465.1 EMC87496.1 - 1.4e-138 444.9 233.8 1.2e-09 37.9 0.2 32.6 33 0 0 33 33 33 26 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87496.1 - 6.4e-106 340.6 289.8 1.1e-05 25.5 1.7 30.9 31 0 0 31 31 31 29 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87496.1 - 2.6e-73 237.1 250.2 0.00043 20.4 0.1 30.7 31 0 0 31 31 31 28 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC87496.1 - 2.2e-42 142.2 177.7 0.0015 18.5 3.2 28.0 29 1 0 29 29 29 18 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC87496.1 - 0.00013 22.0 6.3 0.014 15.5 0.0 26.4 28 0 0 28 28 28 11 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EMC87496.1 - 0.0028 17.2 0.4 0.0028 17.2 0.3 18.4 21 0 0 21 21 21 3 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EMC87496.1 - 0.0039 17.2 4.0 0.0039 17.2 2.8 19.7 11 7 6 19 19 19 10 Drought induced 19 protein (Di19), zinc-binding TerY-C PF15616.1 EMC87496.1 - 0.0064 16.4 0.6 0.0064 16.4 0.4 9.4 8 4 4 12 12 12 2 TerY-C metal binding domain Imm-NTF2-2 PF15631.1 EMC87496.1 - 0.0093 15.9 0.0 17 5.4 0.0 5.3 7 0 0 7 7 7 0 NTF2 fold immunity protein zf-RING_3 PF14369.1 EMC87496.1 - 0.64 10.0 90.1 2.9 7.9 0.2 18.6 20 3 1 21 21 21 0 zinc-finger zf-C2H2 PF00096.21 EMC87497.1 - 7.2e-27 92.0 87.1 0.00026 21.1 4.2 10.8 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87497.1 - 1.5e-20 71.9 80.9 0.0022 18.1 2.5 10.8 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC87497.1 - 6.9e-09 35.5 2.0 6.9e-09 35.5 1.4 13.2 13 1 0 13 13 13 3 Zinc-finger double domain zf-Di19 PF05605.7 EMC87497.1 - 2.9e-05 24.0 34.4 0.97 9.6 0.1 6.1 4 2 0 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 EMC87497.1 - 0.0014 17.2 6.6 0.25 9.8 0.1 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF629) zf-H2C2_5 PF13909.1 EMC87497.1 - 0.0016 18.5 0.4 0.0016 18.5 0.3 8.8 10 0 0 10 10 10 2 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 EMC87497.1 - 0.4 10.4 41.5 0.085 12.5 1.5 7.2 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EMC87497.1 - 0.49 10.5 50.4 0.24 11.5 7.2 7.8 6 2 3 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_2 PF12756.2 EMC87498.1 - 1.2e-12 47.8 21.2 0.0031 17.5 0.8 5.6 4 2 1 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EMC87498.1 - 1.7e-09 37.4 29.0 0.069 13.5 1.0 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87498.1 - 1.3e-07 31.4 19.8 0.058 13.7 1.6 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC87498.1 - 0.0001 22.0 25.8 0.13 12.1 0.4 5.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 EMC87498.1 - 0.0049 17.0 9.4 0.018 15.2 1.4 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF678 PF05077.7 EMC87498.1 - 0.064 13.2 7.6 4.7 7.2 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF678) zf-C2HC_2 PF13913.1 EMC87498.1 - 0.066 12.9 0.2 0.066 12.9 0.1 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.10 EMC87498.1 - 0.095 12.1 1.6 1.7 8.1 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 EMC87498.1 - 0.26 11.2 11.6 4.7 7.2 0.0 5.2 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 EMC87498.1 - 0.46 10.6 22.8 0.19 11.9 0.6 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding ADH_zinc_N PF00107.21 EMC87499.1 - 2.6e-29 101.3 0.0 4.2e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMC87499.1 - 3.4e-10 40.8 0.0 1.9e-09 38.5 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMC87499.1 - 3.8e-09 36.2 0.3 4.7e-06 26.3 0.0 3.2 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EMC87499.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding PHB_acc_N PF07879.6 EMC87500.1 - 0.91 9.3 4.4 0.92 9.2 0.1 3.2 4 1 1 5 5 5 0 PHB/PHA accumulation regulator DNA-binding domain Peptidase_M20 PF01546.23 EMC87501.1 - 1e-33 116.4 0.0 1.6e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMC87501.1 - 3.6e-17 62.1 0.0 9.6e-17 60.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain PIP49_C PF12260.3 EMC87502.1 - 2.7e-59 199.7 0.9 3.9e-59 199.2 0.2 1.5 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 EMC87502.1 - 1.8e-12 47.2 0.3 1.8e-12 47.2 0.2 1.5 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 TIM21 PF08294.6 EMC87504.1 - 1.7e-47 160.7 0.3 2.1e-47 160.4 0.2 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EMC87504.1 - 3.9e-07 29.5 0.0 1.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 F-box-like PF12937.2 EMC87505.1 - 7.8e-11 41.5 0.0 1.8e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC87505.1 - 2e-09 36.8 0.1 4.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Fucokinase PF07959.7 EMC87505.1 - 0.076 11.5 0.0 4.3 5.7 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase CUB PF00431.15 EMC87506.1 - 2.9e-40 136.7 0.1 2.9e-26 91.7 0.0 2.5 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.13 EMC87506.1 - 1.2e-06 28.2 3.9 1.2e-06 28.2 2.7 2.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A C1q PF00386.16 EMC87508.1 - 1.1e-29 102.9 0.3 1.3e-29 102.7 0.2 1.0 1 0 0 1 1 1 1 C1q domain MIP-T3 PF10243.4 EMC87509.1 - 0.87 7.9 73.6 1.1 7.6 51.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rtf2 PF04641.7 EMC87509.1 - 1.2 8.2 42.5 1.4 8.0 29.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1510 PF07423.6 EMC87509.1 - 1.2 8.4 52.5 1.6 8.0 36.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 EMC87509.1 - 2.2 7.0 41.9 2.4 6.9 29.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3807 PF12720.2 EMC87509.1 - 4.8 7.3 40.7 6.5 6.8 28.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2201_N PF13203.1 EMC87509.1 - 6.5 5.8 24.8 7.3 5.6 17.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EMC87509.1 - 8.4 4.2 39.8 9.9 4.0 27.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 EMC87509.1 - 8.9 6.1 20.5 9.6 6.0 14.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.1 EMC87509.1 - 9.4 5.3 33.6 10 5.2 23.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RTTN_N PF14726.1 EMC87510.1 - 6.7e-27 93.9 6.1 2.8e-26 91.9 0.0 5.2 5 1 0 6 6 6 1 Rotatin, an armadillo repeat protein, centriole functioning IRS PF02174.12 EMC87511.1 - 2.9e-29 100.6 0.0 5.4e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 EMC87511.1 - 1.2e-06 28.6 0.7 2.6e-06 27.5 0.5 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC87511.1 - 5.8 7.1 6.8 15 5.8 2.6 2.9 2 2 1 3 3 3 0 Pleckstrin homology domain Myosin_tail_1 PF01576.14 EMC87513.1 - 0.00056 17.7 7.1 0.00074 17.3 4.9 1.1 1 0 0 1 1 1 1 Myosin tail WD40_alt PF14077.1 EMC87513.1 - 0.0014 18.1 0.5 0.07 12.7 0.1 2.6 2 0 0 2 2 2 1 Alternative WD40 repeat motif Filament PF00038.16 EMC87513.1 - 0.011 15.1 4.0 0.017 14.6 2.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein YPEB PF14620.1 EMC87513.1 - 0.031 13.3 0.3 0.033 13.2 0.2 1.2 1 0 0 1 1 1 0 YpeB sporulation ERM PF00769.14 EMC87513.1 - 0.05 13.1 7.6 0.081 12.4 5.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ALIX_LYPXL_bnd PF13949.1 EMC87513.1 - 0.052 12.4 4.3 0.077 11.9 3.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TBPIP PF07106.8 EMC87513.1 - 0.53 9.8 8.3 0.16 11.4 3.5 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apolipoprotein PF01442.13 EMC87513.1 - 0.62 9.5 7.4 0.068 12.6 2.3 1.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Seryl_tRNA_N PF02403.17 EMC87513.1 - 0.64 10.0 7.5 0.24 11.4 1.6 2.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 EMC87513.1 - 0.91 9.2 5.4 0.21 11.3 1.6 1.5 2 0 0 2 2 2 0 Laminin Domain II DUF3166 PF11365.3 EMC87513.1 - 1 9.8 4.7 2.7 8.5 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) BRE1 PF08647.6 EMC87513.1 - 1.3 9.0 10.2 0.55 10.2 5.1 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Matrilin_ccoil PF10393.4 EMC87513.1 - 1.5 8.2 6.8 1.2 8.5 0.7 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CENP-F_leu_zip PF10473.4 EMC87513.1 - 5.2 6.9 14.4 0.62 9.9 6.9 1.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 EMC87513.1 - 6.4 7.5 6.8 11 6.7 1.3 2.4 2 1 1 3 3 2 0 Occludin homology domain DUF972 PF06156.8 EMC87513.1 - 7.5 6.9 6.5 4.2 7.7 2.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Thioredoxin PF00085.15 EMC87514.1 - 1.7e-27 95.1 0.0 1.4e-25 88.9 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 EMC87514.1 - 6.1e-26 91.3 0.1 1.9e-23 83.2 0.3 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EMC87514.1 - 2.9e-07 30.6 0.1 9.1e-06 25.8 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC87514.1 - 3.4e-05 23.8 0.2 0.055 13.5 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin-like Calsequestrin PF01216.12 EMC87514.1 - 0.009 14.8 0.2 0.015 14.0 0.2 1.4 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.1 EMC87514.1 - 0.023 14.7 0.3 0.087 12.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like SH3_5 PF08460.5 EMC87514.1 - 0.062 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Transglut_C PF00927.17 EMC87515.1 - 8.6e-28 96.5 0.0 1.5e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 EMC87515.1 - 2.1e-11 44.0 0.1 4.5e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Snf7 PF03357.16 EMC87517.1 - 2.8e-50 170.0 20.5 3.2e-50 169.8 14.2 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 EMC87517.1 - 0.00071 19.7 1.6 0.00071 19.7 1.1 2.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein BCDHK_Adom3 PF10436.4 EMC87517.1 - 0.055 12.9 2.1 0.074 12.5 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Prefoldin_2 PF01920.15 EMC87517.1 - 0.079 12.7 22.1 0.53 10.0 0.6 3.4 2 1 1 3 3 3 0 Prefoldin subunit BTV_NS2 PF04514.7 EMC87517.1 - 0.11 11.4 10.9 0.13 11.1 7.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF45 PF01863.12 EMC87517.1 - 0.5 10.1 6.5 0.52 10.0 3.9 1.4 1 1 1 2 2 2 0 Protein of unknown function DUF45 His_binding PF02098.11 EMC87517.1 - 0.65 9.7 4.0 1.1 9.0 2.7 1.4 1 1 0 1 1 1 0 Tick histamine binding protein GvpK PF05121.7 EMC87517.1 - 0.72 9.7 11.7 0.84 9.4 1.8 3.1 2 1 1 3 3 3 0 Gas vesicle protein K DUF848 PF05852.6 EMC87517.1 - 0.85 9.4 10.3 0.39 10.5 4.8 2.1 1 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) PRA-PH PF01503.12 EMC87517.1 - 1.4 9.2 4.4 2 8.7 2.4 1.8 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF948 PF06103.6 EMC87517.1 - 3.8 7.4 6.7 1.5 8.7 2.3 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EMC87517.1 - 4.6 6.8 11.8 29 4.1 8.2 2.0 1 1 0 1 1 1 0 IncA protein CorA PF01544.13 EMC87517.1 - 6.4 5.7 15.6 7.3 5.5 6.1 2.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein PEP-utilisers_N PF05524.8 EMC87517.1 - 7.6 6.3 11.1 0.93 9.2 1.3 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal BAG PF02179.11 EMC87518.1 - 2.7e-12 46.6 4.3 1.2e-11 44.5 3.0 2.0 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EMC87518.1 - 9.6e-08 31.3 0.3 2.2e-07 30.1 0.0 1.7 2 0 0 2 2 1 1 Ubiquitin family PHTB1_C PF14728.1 EMC87518.1 - 4.4e-06 25.7 1.1 4.8e-06 25.6 0.7 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus YPEB PF14620.1 EMC87518.1 - 0.00091 18.3 0.6 0.0014 17.7 0.4 1.3 1 0 0 1 1 1 1 YpeB sporulation V_ATPase_I PF01496.14 EMC87518.1 - 0.0026 15.6 1.1 0.0029 15.5 0.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Nup54 PF13874.1 EMC87518.1 - 0.054 13.1 3.3 2.3 7.8 0.1 2.5 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Uds1 PF15456.1 EMC87518.1 - 0.082 12.9 1.6 0.2 11.6 0.2 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Sigma54_DBD PF04552.8 EMC87518.1 - 0.083 12.4 0.7 0.14 11.6 0.4 1.4 1 1 0 1 1 1 0 Sigma-54, DNA binding domain DUF3786 PF12654.2 EMC87518.1 - 0.084 12.1 0.2 0.14 11.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3786) DUF4041 PF13250.1 EMC87518.1 - 0.11 12.0 1.3 3.3 7.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4041) Spectrin PF00435.16 EMC87518.1 - 0.12 12.7 4.1 1.3 9.3 2.5 2.3 2 0 0 2 2 2 0 Spectrin repeat Occludin_ELL PF07303.8 EMC87518.1 - 0.15 12.8 2.6 0.45 11.2 1.7 2.0 1 1 0 1 1 1 0 Occludin homology domain MscS_porin PF12795.2 EMC87518.1 - 0.15 11.3 4.6 0.32 10.2 3.2 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain MitMem_reg PF13012.1 EMC87518.1 - 0.16 12.0 1.9 2.9 8.0 1.3 2.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF1664 PF07889.7 EMC87518.1 - 0.19 11.5 4.1 0.96 9.2 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EMC87518.1 - 0.19 11.5 1.6 0.48 10.2 1.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EMC87518.1 - 0.3 10.6 7.5 0.46 10.0 5.1 1.6 1 1 0 1 1 1 0 IncA protein AATF-Che1 PF13339.1 EMC87518.1 - 0.31 11.1 3.7 0.44 10.6 2.1 1.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor WXG100 PF06013.7 EMC87518.1 - 0.38 10.7 2.3 8.7 6.4 0.0 2.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Fib_alpha PF08702.5 EMC87518.1 - 0.42 10.7 3.2 0.6 10.2 1.8 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2408 PF10303.4 EMC87518.1 - 0.58 10.2 4.4 0.97 9.5 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF342 PF03961.8 EMC87518.1 - 0.7 8.2 8.9 1.3 7.3 6.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF1319 PF07028.6 EMC87518.1 - 0.88 9.7 6.9 0.6 10.3 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) NYD-SP28 PF14772.1 EMC87518.1 - 1 9.4 6.7 1.9 8.6 3.7 2.1 1 1 0 2 2 2 0 Sperm tail Erp_C PF06780.6 EMC87518.1 - 1.2 8.9 6.7 4.4 7.1 4.0 2.1 1 1 1 2 2 2 0 Erp protein C-terminus TMF_DNA_bd PF12329.3 EMC87518.1 - 1.2 9.0 11.9 0.27 11.0 1.9 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 EMC87518.1 - 1.2 9.1 11.5 0.97 9.4 6.1 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 EMC87518.1 - 1.7 8.1 8.2 3.3 7.2 5.4 1.6 1 1 0 1 1 1 0 GrpE Laminin_II PF06009.7 EMC87518.1 - 1.9 8.2 6.9 1.3 8.7 0.7 2.6 2 1 1 3 3 3 0 Laminin Domain II FliJ PF02050.11 EMC87518.1 - 3 7.9 9.1 1.2 9.1 4.5 1.7 2 0 0 2 2 1 0 Flagellar FliJ protein Prefoldin PF02996.12 EMC87518.1 - 3.2 7.4 10.4 0.85 9.2 1.0 2.6 2 1 1 3 3 3 0 Prefoldin subunit DUF16 PF01519.11 EMC87518.1 - 8.4 6.6 9.9 14 5.9 6.2 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 7tm_4 PF13853.1 EMC87520.1 - 2.1e-60 202.7 11.8 2.1e-60 202.7 8.2 2.7 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC87520.1 - 3.3e-33 114.9 16.6 4.1e-33 114.5 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87520.1 - 0.058 12.5 15.7 0.11 11.5 10.4 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1980 PF09323.5 EMC87520.1 - 0.16 11.7 1.9 0.33 10.6 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) ECH PF00378.15 EMC87521.1 - 3.8e-07 29.4 0.0 6.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family PAAR_motif PF05488.8 EMC87521.1 - 0.55 10.2 4.7 0.32 11.0 1.4 2.2 2 1 0 2 2 2 0 PAAR motif Shal-type PF11601.3 EMC87522.1 - 0.34 10.4 4.1 45 3.6 0.0 3.2 3 0 0 3 3 3 0 Shal-type voltage-gated potassium channels TLV_coat PF00429.14 EMC87523.1 - 3.2e-48 164.5 0.9 3.5e-48 164.4 0.6 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC87523.1 - 0.0044 16.6 0.0 0.0047 16.5 0.0 1.0 1 0 0 1 1 1 1 Retroviral envelope protein DUF2951 PF11166.3 EMC87523.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) THOC7 PF05615.8 EMC87523.1 - 0.09 13.0 0.2 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 TLV_coat PF00429.14 EMC87524.1 - 3.5e-12 45.5 6.2 4.2e-12 45.3 4.3 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DUF1073 PF06381.6 EMC87524.1 - 0.045 12.1 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) GP41 PF00517.12 EMC87524.1 - 0.73 9.3 6.6 0.14 11.7 1.9 1.7 1 1 1 2 2 2 0 Retroviral envelope protein SdpI PF13630.1 EMC87524.1 - 1.1 9.0 5.8 10 5.9 0.1 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family Ephrin PF00812.12 EMC87526.1 - 5.2e-47 159.0 0.3 6.3e-47 158.7 0.2 1.1 1 0 0 1 1 1 1 Ephrin PTH2 PF01981.11 EMC87527.1 - 0.018 14.6 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 LRR_6 PF13516.1 EMC87528.1 - 2.4e-13 48.6 7.2 0.57 10.4 0.0 9.1 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.2 EMC87528.1 - 3.4e-08 33.0 4.4 3.4e-08 33.0 3.1 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EMC87528.1 - 4e-06 26.3 7.9 0.22 11.1 0.0 5.5 3 3 3 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EMC87528.1 - 0.00023 20.7 5.0 0.00039 19.9 1.7 2.8 3 1 0 3 3 3 1 F-box domain LRR_8 PF13855.1 EMC87528.1 - 0.0004 20.0 7.1 0.61 9.8 0.1 4.7 2 1 4 6 6 6 3 Leucine rich repeat Aldedh PF00171.17 EMC87528.1 - 0.033 12.5 0.0 0.067 11.5 0.0 1.4 2 0 0 2 2 2 0 Aldehyde dehydrogenase family LRR_1 PF00560.28 EMC87528.1 - 0.45 10.7 11.3 29 5.2 0.0 6.1 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 EMC87528.1 - 1.7 9.1 10.6 2.1 8.9 0.0 5.1 4 1 0 4 4 4 0 Leucine rich repeat Pkinase_Tyr PF07714.12 EMC87529.1 - 7.2e-103 343.1 0.1 2.7e-102 341.2 0.0 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 EMC87529.1 - 2.2e-53 181.0 0.0 6.8e-53 179.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EMC87529.1 - 2.3e-22 78.5 0.0 8e-22 76.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain FCH PF00611.18 EMC87529.1 - 8.5e-18 64.3 1.6 8.5e-18 64.3 1.1 3.9 3 1 1 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain zf-RING_2 PF13639.1 EMC87530.1 - 2.1e-14 53.0 11.7 3.8e-14 52.2 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC87530.1 - 2.7e-07 30.4 11.4 5e-07 29.6 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC87530.1 - 1.2e-06 28.0 10.7 2.5e-06 27.0 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87530.1 - 2.4e-06 27.1 9.4 4.2e-06 26.3 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC87530.1 - 4.4e-06 26.7 11.7 1.2e-05 25.3 8.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC87530.1 - 6.3e-06 25.7 7.8 1.3e-05 24.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC87530.1 - 0.00037 20.2 4.3 0.00078 19.2 3.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMC87530.1 - 0.013 15.4 11.8 0.032 14.2 8.2 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EMC87530.1 - 0.32 11.0 12.4 1.7 8.6 8.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EMC87530.1 - 2.6 7.6 7.3 6.7 6.3 5.1 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMC87530.1 - 3.9 7.2 6.6 1.6 8.4 2.6 1.9 1 1 1 2 2 2 0 RING-type zinc-finger Glyco_hydro_38 PF01074.17 EMC87531.1 - 4.8e-98 327.7 5.3 7.9e-98 327.0 3.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EMC87531.1 - 3.1e-79 266.8 0.0 4.7e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EMC87531.1 - 3.8e-26 91.1 0.0 8.6e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain DUF1664 PF07889.7 EMC87531.1 - 0.13 12.0 1.1 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Polysacc_deac_1 PF01522.16 EMC87531.1 - 0.14 11.7 0.0 0.53 9.9 0.0 1.9 1 1 0 1 1 1 0 Polysaccharide deacetylase Mito_carr PF00153.22 EMC87532.1 - 1.7e-18 66.1 0.1 7e-12 44.9 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein Utp21 PF04192.7 EMC87533.1 - 4.4e-70 235.4 0.1 6e-70 235.0 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EMC87533.1 - 3.9e-28 96.2 8.7 1e-10 41.0 0.5 8.6 9 0 0 9 9 9 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC87533.1 - 0.0046 15.7 2.8 2.2 6.9 0.0 3.3 2 2 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EMC87533.1 - 0.018 13.3 0.0 0.033 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain SGL PF08450.7 EMC87533.1 - 0.094 12.0 0.0 0.49 9.7 0.0 2.2 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Utp12 PF04003.7 EMC87533.1 - 0.15 11.9 3.9 0.39 10.6 1.9 2.0 2 0 0 2 2 2 0 Dip2/Utp12 Family Pkinase PF00069.20 EMC87534.1 - 2.2e-52 177.7 0.0 2.5e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87534.1 - 3.4e-18 65.6 0.0 4.1e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87534.1 - 1.6e-05 24.0 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMC87534.1 - 0.0083 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EMC87534.1 - 0.026 13.6 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC87534.1 - 0.043 13.5 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Alveol-reg_P311 PF11092.3 EMC87535.1 - 2e-31 107.7 0.0 2.3e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Neuronal protein 3.1 (p311) SRP19 PF01922.12 EMC87536.1 - 9.5e-30 103.0 0.1 1.2e-29 102.7 0.1 1.1 1 0 0 1 1 1 1 SRP19 protein NUDIX PF00293.23 EMC87537.1 - 0.061 12.9 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 NUDIX domain MCC-bdg_PDZ PF10506.4 EMC87538.1 - 7.1e-60 198.7 40.1 6.1e-29 99.6 4.8 6.3 6 0 0 6 6 6 3 PDZ domain of MCC-2 bdg protein for Usher syndrome ERM PF00769.14 EMC87538.1 - 0.00026 20.5 70.8 0.00059 19.4 6.8 5.1 4 2 0 4 4 4 2 Ezrin/radixin/moesin family APG6 PF04111.7 EMC87538.1 - 0.011 14.8 1.3 0.011 14.8 0.9 5.7 4 1 1 6 6 6 0 Autophagy protein Apg6 DUF1359 PF07097.6 EMC87538.1 - 0.062 13.3 7.5 0.83 9.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1359) GAS PF13851.1 EMC87538.1 - 3.7 6.6 71.0 0.25 10.5 0.9 6.0 6 0 0 6 6 6 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EMC87538.1 - 6.4 4.3 78.0 0.061 11.0 11.4 4.3 3 1 0 4 4 4 0 Myosin tail CaMBD PF02888.11 EMC87539.1 - 6.5e-36 121.9 9.2 6.5e-36 121.9 6.4 2.1 2 0 0 2 2 2 1 Calmodulin binding domain SK_channel PF03530.9 EMC87539.1 - 6.9e-36 122.6 1.3 6.9e-36 122.6 0.9 2.2 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.11 EMC87539.1 - 3.4e-13 49.1 3.0 3.4e-13 49.1 2.1 2.0 2 0 0 2 2 2 1 Ion channel Med9 PF07544.8 EMC87539.1 - 0.0064 16.2 0.2 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 EMC87539.1 - 1.3 8.8 11.5 29 4.4 5.9 3.2 1 1 1 2 2 2 0 Prefoldin subunit Prenyltrans PF00432.16 EMC87541.1 - 6.2e-41 137.6 8.1 7.5e-10 38.2 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMC87541.1 - 1.3e-16 60.9 0.0 2.9e-09 37.3 0.0 3.4 2 1 2 4 4 4 3 Prenyltransferase-like Ank_2 PF12796.2 EMC87542.1 - 5.6e-74 244.5 14.8 5.9e-24 84.2 0.5 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMC87542.1 - 2.8e-60 197.2 16.1 4.7e-08 32.4 0.0 8.8 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 EMC87542.1 - 3.1e-43 141.4 12.4 1.3e-06 28.0 0.0 10.3 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 EMC87542.1 - 5e-42 141.5 6.5 6e-10 39.3 0.0 7.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC87542.1 - 1e-39 133.6 13.2 2.2e-09 37.2 0.2 8.1 4 2 5 9 9 9 7 Ankyrin repeats (many copies) TPR_12 PF13424.1 EMC87542.1 - 1.6e-05 24.7 0.0 0.009 15.9 0.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC87542.1 - 0.019 14.8 0.7 0.36 10.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMC87542.1 - 0.11 12.4 0.1 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CDO_I PF05995.7 EMC87544.1 - 4.1e-47 159.5 0.1 4.8e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EMC87544.1 - 1.5e-05 24.4 0.4 2.9e-05 23.5 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) 2OG-FeII_Oxy_4 PF13661.1 EMC87544.1 - 0.029 13.9 0.2 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Clat_adaptor_s PF01217.15 EMC87545.1 - 1.2e-41 141.7 2.9 1.4e-41 141.5 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M1 PF01433.15 EMC87546.1 - 1e-88 298.0 0.1 1.8e-88 297.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMC87546.1 - 1.4e-21 77.1 0.6 2.1e-21 76.5 0.4 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMC87546.1 - 1.1e-10 41.6 0.0 3.4e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Peptidase MA superfamily ARF7EP_C PF14949.1 EMC87547.1 - 1.6e-35 121.6 11.1 1.9e-35 121.4 7.7 1.0 1 0 0 1 1 1 1 ARF7 effector protein C-terminus HCaRG PF07258.9 EMC87548.1 - 3e-29 101.8 8.1 3.6e-29 101.5 5.6 1.0 1 0 0 1 1 1 1 HCaRG protein IZUMO PF15005.1 EMC87548.1 - 0.13 12.3 1.7 0.26 11.3 1.2 1.5 1 1 0 1 1 1 0 Izumo sperm-egg fusion Sema PF01403.14 EMC87549.1 - 2.8e-141 470.9 0.1 2.8e-141 470.9 0.1 1.4 2 0 0 2 2 2 1 Sema domain PSI PF01437.20 EMC87549.1 - 3.3e-08 33.5 2.4 7.1e-08 32.4 1.6 1.6 1 0 0 1 1 1 1 Plexin repeat DTW PF03942.10 EMC87551.1 - 1.2e-45 155.3 0.3 1.5e-45 154.9 0.2 1.1 1 0 0 1 1 1 1 DTW domain Rav1p_C PF12234.3 EMC87552.1 - 3.7e-73 246.7 0.0 1.1e-70 238.6 0.0 3.2 2 1 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 EMC87552.1 - 6.6e-28 95.5 27.7 3.1e-06 26.8 0.0 12.4 13 0 0 13 13 13 8 WD domain, G-beta repeat DUF758 PF05527.6 EMC87553.1 - 6.2e-93 309.5 8.5 7e-93 309.4 5.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) RAG1 PF12940.2 EMC87553.1 - 0.00051 18.5 0.8 0.00063 18.2 0.5 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) Pico_P2B PF01552.12 EMC87553.1 - 0.0043 17.1 1.0 0.013 15.6 0.3 2.1 1 1 0 1 1 1 1 Picornavirus 2B protein CH PF00307.26 EMC87553.1 - 0.0079 16.2 0.1 0.022 14.8 0.0 2.0 1 1 0 1 1 1 1 Calponin homology (CH) domain Nup54 PF13874.1 EMC87553.1 - 0.016 14.8 2.1 0.019 14.6 0.9 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FadR_C PF07840.7 EMC87553.1 - 0.017 14.7 0.7 0.024 14.2 0.5 1.4 1 0 0 1 1 1 0 FadR C-terminal domain UCH PF00443.24 EMC87553.1 - 0.035 13.2 1.4 0.043 12.9 1.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2408 PF10303.4 EMC87553.1 - 0.049 13.7 4.4 0.1 12.6 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HD_3 PF13023.1 EMC87553.1 - 0.066 12.9 0.6 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 HD domain MaoC_dehydratas PF01575.14 EMC87554.1 - 2.4e-36 123.7 0.0 4.4e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain SCP2 PF02036.12 EMC87554.1 - 6.7e-25 87.3 0.3 1.7e-24 86.0 0.2 1.7 1 0 0 1 1 1 1 SCP-2 sterol transfer family adh_short PF00106.20 EMC87554.1 - 1e-21 77.5 0.0 2.1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase MaoC_dehydrat_N PF13452.1 EMC87554.1 - 5.2e-11 42.4 0.0 3.3e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase KR PF08659.5 EMC87554.1 - 9.6e-11 41.6 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 EMC87554.1 - 6.7e-08 32.5 0.1 1.6e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF4589 PF15252.1 EMC87555.1 - 4.9e-69 232.5 0.2 5.5e-69 232.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) BUD22 PF09073.5 EMC87556.1 - 2.2e-10 40.1 8.0 2.2e-10 40.1 5.5 2.1 1 1 1 2 2 2 1 BUD22 Tom22 PF04281.8 EMC87556.1 - 0.56 9.7 4.3 1.1 8.7 3.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4196 PF13846.1 EMC87556.1 - 2.7 8.3 14.8 0.72 10.1 7.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4196) Lysyl_oxidase PF01186.12 EMC87557.1 - 6.7e-101 336.1 7.6 7.4e-101 336.0 5.2 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.6 EMC87557.1 - 0.0028 17.6 0.0 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 CARDB zf-C2HC_2 PF13913.1 EMC87558.1 - 2.3e-18 65.3 7.0 4.5e-10 38.9 0.4 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 EMC87558.1 - 0.00018 21.6 4.7 0.016 15.5 0.1 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type c-SKI_SMAD_bind PF08782.5 EMC87558.1 - 0.02 15.0 1.3 0.049 13.7 0.1 1.9 2 0 0 2 2 2 0 c-SKI Smad4 binding domain Sgf11 PF08209.6 EMC87558.1 - 0.024 13.9 0.2 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_ribbon_recom PF13408.1 EMC87558.1 - 0.08 13.2 1.3 4.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2318 PF10080.4 EMC87558.1 - 0.098 12.4 1.1 8 6.2 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Rad50_zn_hook PF04423.9 EMC87558.1 - 0.13 11.7 0.5 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.1 EMC87558.1 - 0.13 12.2 6.0 1.4 8.9 0.7 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 EMC87558.1 - 0.13 11.9 0.9 14 5.4 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMC87558.1 - 0.15 11.6 1.0 14 5.3 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 EMC87558.1 - 1.1 9.6 3.4 6.2 7.2 0.0 2.7 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 EMC87559.1 - 3.2e-20 71.2 6.5 2e-11 43.2 0.5 2.6 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 EMC87559.1 - 0.0068 16.6 4.6 0.02 15.1 0.1 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type Sgf11 PF08209.6 EMC87559.1 - 0.019 14.2 1.3 0.37 10.1 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Lar_restr_allev PF14354.1 EMC87559.1 - 0.04 14.2 2.1 5.8 7.3 0.3 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-HC5HC2H PF13771.1 EMC87559.1 - 0.091 12.9 0.2 0.93 9.6 0.1 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain BIR PF00653.16 EMC87559.1 - 0.2 12.0 1.9 30 5.1 1.0 2.8 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain zf-H2C2_2 PF13465.1 EMC87559.1 - 1.3 9.4 4.3 2.6 8.4 0.0 3.1 4 0 0 4 4 4 0 Zinc-finger double domain DUF4428 PF14471.1 EMC87559.1 - 2.4 7.9 4.5 9.3 6.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-C2H2_4 PF13894.1 EMC87559.1 - 5.8 7.4 6.9 11 6.6 0.5 3.0 2 2 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.2 EMC87560.1 - 2.3e-20 72.7 3.8 3.1e-09 37.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC87560.1 - 5.3e-18 65.0 0.1 2.6e-07 30.9 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC87560.1 - 3.4e-15 55.7 1.8 2.3e-05 24.5 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC87560.1 - 4.4e-14 51.4 3.6 1.1e-07 31.2 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EMC87560.1 - 4.1e-08 32.7 0.9 0.015 15.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Vps5 PF09325.5 EMC87561.1 - 2.6e-85 285.4 19.1 2.6e-85 285.4 13.2 1.4 2 0 0 2 2 2 1 Vps5 C terminal like Sorting_nexin PF03700.8 EMC87561.1 - 1.2e-32 112.7 4.2 2.5e-32 111.7 2.9 1.6 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain PX PF00787.19 EMC87561.1 - 3.5e-30 104.0 0.4 1.2e-28 99.1 0.1 2.4 2 0 0 2 2 2 1 PX domain SH3BP5 PF05276.9 EMC87561.1 - 0.0093 15.2 7.8 0.3 10.3 0.2 2.7 3 0 0 3 3 3 2 SH3 domain-binding protein 5 (SH3BP5) GAS PF13851.1 EMC87561.1 - 0.32 10.1 18.1 0.19 10.9 2.8 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EMC87561.1 - 0.38 9.3 16.6 0.17 10.5 3.2 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF3138 PF11336.3 EMC87561.1 - 0.43 8.6 3.5 0.66 8.0 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Tropomyosin PF00261.15 EMC87561.1 - 0.44 9.5 17.3 0.019 14.0 2.8 2.4 2 0 0 2 2 2 0 Tropomyosin Reo_sigmaC PF04582.7 EMC87561.1 - 0.51 9.4 2.8 0.47 9.5 0.6 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein HR1 PF02185.11 EMC87561.1 - 0.61 9.8 10.9 2.2 8.1 0.1 3.6 3 0 0 3 3 3 0 Hr1 repeat DUF4618 PF15397.1 EMC87561.1 - 1.5 8.1 13.4 0.94 8.7 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF848 PF05852.6 EMC87561.1 - 2.2 8.1 14.0 0.52 10.1 3.5 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Allexi_40kDa PF05549.6 EMC87561.1 - 2.8 7.1 7.9 0.51 9.5 0.5 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein GrpE PF01025.14 EMC87561.1 - 5.6 6.4 18.4 0.11 11.9 4.0 2.7 2 1 0 2 2 2 0 GrpE 4HB_MCP_1 PF12729.2 EMC87561.1 - 8.2 5.7 12.1 0.84 8.9 1.7 2.8 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction PX PF00787.19 EMC87562.1 - 5.2e-14 52.0 2.8 7.6e-14 51.4 1.5 1.6 1 1 1 2 2 2 1 PX domain Pro_isomerase PF00160.16 EMC87563.1 - 3.4e-45 154.0 0.1 3.9e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-H2C2_2 PF13465.1 EMC87564.1 - 1.2e-13 50.5 13.6 5.6e-05 23.2 0.1 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87564.1 - 1.9e-12 46.7 19.6 5.4e-05 23.2 1.0 4.6 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87564.1 - 9e-11 41.3 13.7 0.0016 18.6 1.0 4.5 3 0 0 3 3 3 3 C2H2-type zinc finger SET PF00856.23 EMC87564.1 - 4.5e-07 30.3 0.2 6.8e-06 26.4 0.1 2.5 1 1 0 1 1 1 1 SET domain zf-C2H2_jaz PF12171.3 EMC87564.1 - 0.0014 18.6 0.6 0.038 14.1 0.0 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC87564.1 - 0.0033 17.5 3.7 0.012 15.7 1.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EMC87564.1 - 0.012 15.4 9.3 0.64 9.9 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 EMC87564.1 - 0.14 11.9 4.8 0.72 9.6 0.1 3.2 3 0 0 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.1 EMC87564.1 - 0.32 10.7 0.0 0.32 10.7 0.0 3.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type SprT-like PF10263.4 EMC87564.1 - 0.62 9.7 5.6 1.7 8.2 2.3 2.5 2 1 0 2 2 2 0 SprT-like family zf-CHCC PF10276.4 EMC87564.1 - 1.3 8.8 5.2 0.71 9.7 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.7 EMC87564.1 - 3.7 7.7 13.1 2 8.6 0.0 3.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMC87564.1 - 7.9 6.6 8.1 29 4.8 0.0 3.5 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) TLV_coat PF00429.14 EMC87565.1 - 0.086 11.2 0.1 0.094 11.1 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) DUF2132 PF09905.4 EMC87565.1 - 0.13 12.1 0.2 0.6 10.1 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2132) SGT1 PF07093.6 EMC87566.1 - 1.1e-176 588.7 0.4 1.3e-176 588.4 0.3 1.0 1 0 0 1 1 1 1 SGT1 protein DUF3719 PF12516.3 EMC87567.1 - 1.2e-18 66.3 0.1 4.2e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) Ndc1_Nup PF09531.5 EMC87567.1 - 1.7 6.9 4.1 0.87 7.9 0.3 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup HMG_box PF00505.14 EMC87568.1 - 7.3e-28 96.6 9.2 4e-19 68.6 2.0 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC87568.1 - 1.7e-17 63.5 17.8 3.8e-10 40.0 2.3 3.3 3 1 0 3 3 3 2 HMG-box domain DegS PF05384.6 EMC87568.1 - 0.068 12.3 0.3 0.068 12.3 0.2 2.0 2 0 0 2 2 2 0 Sensor protein DegS YABBY PF04690.8 EMC87568.1 - 0.086 13.0 0.3 0.086 13.0 0.2 2.6 1 1 2 3 3 3 0 YABBY protein DUF1074 PF06382.6 EMC87568.1 - 1.9 8.4 10.0 5.9 6.8 0.8 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1074) UQ_con PF00179.21 EMC87569.1 - 1.8e-51 173.2 0.0 2e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC87569.1 - 6.6e-05 22.6 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC87569.1 - 0.00058 19.7 0.0 0.00083 19.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMC87569.1 - 0.05 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-CDGSH PF09360.5 EMC87571.1 - 2.4e-12 46.4 0.3 3.7e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.4 EMC87571.1 - 5.9e-10 38.8 0.6 8e-10 38.4 0.4 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus IPK PF03770.11 EMC87572.1 - 2e-66 223.3 0.4 2.8e-66 222.9 0.3 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase dUTPase PF00692.14 EMC87573.1 - 4.5e-14 52.0 0.0 5.7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase PT PF04886.7 EMC87575.1 - 0.0032 16.7 0.4 0.19 11.0 0.0 3.1 2 1 0 2 2 2 1 PT repeat Yae1_N PF09811.4 EMC87576.1 - 2.7e-16 58.7 44.7 0.025 14.0 4.0 5.1 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Prokineticin PF06607.6 EMC87580.1 - 0.00023 21.1 5.8 0.00034 20.6 4.0 1.3 1 0 0 1 1 1 1 Prokineticin UPF0506 PF11703.3 EMC87580.1 - 7.9 6.5 13.7 2.3 8.2 1.2 3.2 1 1 2 3 3 3 0 UPF0506 Pkinase PF00069.20 EMC87581.1 - 4e-69 232.6 0.0 5e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87581.1 - 3.5e-36 124.6 0.0 4.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 EMC87581.1 - 4.9e-22 77.5 0.0 1.2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Kinase-like PF14531.1 EMC87581.1 - 1.1e-05 24.5 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC87581.1 - 0.021 14.5 0.0 0.31 10.7 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 EMC87581.1 - 0.18 12.3 6.1 0.12 12.8 2.8 1.9 2 0 0 2 2 2 0 Protein kinase C terminal domain cNMP_binding PF00027.24 EMC87582.1 - 5.8e-06 26.0 0.0 9.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RRM_1 PF00076.17 EMC87583.1 - 2e-40 136.2 1.5 3.7e-17 61.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC87583.1 - 3.7e-32 110.1 0.5 1.6e-10 40.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 EMC87583.1 - 5.6e-30 103.4 0.2 1.4e-29 102.2 0.1 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_5 PF13893.1 EMC87583.1 - 8.3e-23 80.0 0.4 2e-08 33.9 0.2 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC87583.1 - 0.00059 19.5 0.2 0.23 11.2 0.0 2.6 3 0 0 3 3 3 2 Limkain b1 dsrm PF00035.20 EMC87583.1 - 0.058 13.9 0.7 2.2 8.9 0.0 3.0 3 0 0 3 3 3 0 Double-stranded RNA binding motif Ceramidase_alk PF04734.8 EMC87584.1 - 1.6e-272 905.4 0.0 1.8e-272 905.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase PAP2_C PF14360.1 EMC87585.1 - 4.8e-30 103.6 14.7 4.8e-30 103.6 10.2 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EMC87585.1 - 5.7e-06 26.0 9.2 5.7e-06 26.0 6.4 1.9 2 1 0 2 2 2 1 PAP2 superfamily SAM_1 PF00536.25 EMC87585.1 - 0.0003 20.8 0.0 0.0007 19.7 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_3 PF14378.1 EMC87585.1 - 0.00033 20.2 7.7 0.00033 20.2 5.3 1.8 1 1 1 2 2 2 1 PAP2 superfamily SAM_2 PF07647.12 EMC87585.1 - 0.0041 16.9 0.1 0.0096 15.7 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC87585.1 - 0.13 12.0 0.2 0.13 12.0 0.1 2.9 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain His_Phos_2 PF00328.17 EMC87586.1 - 2.2e-18 66.7 0.1 2.6e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) APS_kinase PF01583.15 EMC87587.1 - 5e-73 243.9 0.0 8e-73 243.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 EMC87587.1 - 1.1e-67 227.5 0.0 1.5e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EMC87587.1 - 8e-45 152.1 0.0 1.5e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EMC87587.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC87587.1 - 1.6e-05 25.7 0.1 6e-05 23.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMC87587.1 - 0.00033 20.9 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMC87588.1 - 9.8e-37 126.0 0.0 3.1e-36 124.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC87588.1 - 1.1e-06 28.7 0.1 0.00042 20.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC87588.1 - 8.1e-06 25.9 1.0 0.00045 20.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EMC87588.1 - 1.2e-05 26.0 0.1 4.8e-05 24.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EMC87588.1 - 1.4e-05 24.2 0.0 4.9e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMC87588.1 - 2e-05 24.5 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC87588.1 - 3.1e-05 23.4 1.0 0.18 11.1 0.1 2.6 2 1 1 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EMC87588.1 - 9.7e-05 21.5 0.2 0.00034 19.7 0.0 2.0 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.9 EMC87588.1 - 0.00011 21.8 0.1 0.0012 18.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMC87588.1 - 0.0025 17.7 0.0 0.0061 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EMC87588.1 - 0.0026 17.2 0.1 0.26 10.7 0.0 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EMC87588.1 - 0.003 16.7 0.1 0.035 13.2 0.0 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EMC87588.1 - 0.0048 16.3 0.1 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 EMC87588.1 - 0.0065 16.7 0.3 0.038 14.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.10 EMC87588.1 - 0.0072 15.0 0.2 0.017 13.8 0.1 1.8 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein SKI PF01202.17 EMC87588.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase AAA_2 PF07724.9 EMC87588.1 - 0.012 15.5 0.0 0.046 13.6 0.0 2.0 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EMC87588.1 - 0.015 15.2 1.3 0.89 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EMC87588.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EMC87588.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 EMC87588.1 - 0.024 14.7 0.4 0.21 11.6 0.0 2.8 3 1 0 3 3 2 0 Sigma-54 interaction domain TIP49 PF06068.8 EMC87588.1 - 0.028 13.1 0.0 0.063 11.9 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 EMC87588.1 - 0.03 13.5 0.1 0.43 9.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EMC87588.1 - 0.041 13.4 0.1 0.15 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EMC87588.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMC87588.1 - 0.08 12.0 0.2 0.75 8.8 0.0 2.5 2 1 1 3 3 3 0 KaiC AAA_21 PF13304.1 EMC87588.1 - 0.14 12.1 0.7 1.6 8.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EMC87588.1 - 0.16 12.2 0.4 1.2 9.4 0.0 2.5 3 1 0 3 3 3 0 ABC transporter AAA_10 PF12846.2 EMC87588.1 - 0.23 10.8 1.6 6.3 6.1 0.0 2.9 3 1 0 3 3 3 0 AAA-like domain PTEN_C2 PF10409.4 EMC87589.1 - 4e-44 149.5 3.2 6.3e-44 148.9 2.2 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 EMC87589.1 - 9.4e-09 34.9 0.0 4.2e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC87589.1 - 3.1e-05 23.4 0.0 7.6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMC87589.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC87589.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate DUF3256 PF11644.3 EMC87589.1 - 0.02 14.3 0.3 0.052 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) Abhydro_lipase PF04083.11 EMC87590.1 - 2.1e-19 68.6 0.1 3.8e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMC87590.1 - 5.9e-17 61.9 0.0 1.1e-16 61.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC87590.1 - 1.1e-06 28.4 0.1 1.3e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC87590.1 - 1.8e-05 24.7 0.0 3.6e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family RE_NgoFVII PF09565.5 EMC87590.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Abhydro_lipase PF04083.11 EMC87591.1 - 2.7e-20 71.4 0.0 5.4e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMC87591.1 - 3.8e-20 72.4 0.3 5.9e-20 71.8 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC87591.1 - 1.1e-10 41.3 0.0 3e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC87591.1 - 8.4e-09 35.6 0.2 1.5e-08 34.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EMC87591.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2305 PF10230.4 EMC87591.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) VirJ PF06057.6 EMC87591.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF900 PF05990.7 EMC87591.1 - 0.13 11.5 0.1 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Amino_oxidase PF01593.19 EMC87592.1 - 1.6e-67 228.5 0.0 1.8e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase MMR_HSR1 PF01926.18 EMC87593.1 - 1.3e-12 47.6 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC87593.1 - 1.2e-05 24.6 0.0 0.00013 21.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMC87593.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMC87593.1 - 0.0031 16.6 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EMC87593.1 - 0.0099 15.7 0.5 0.95 9.2 0.1 2.2 1 1 1 2 2 2 1 Dynamin family Ras PF00071.17 EMC87593.1 - 0.0099 15.2 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Ras family ATP_bind_1 PF03029.12 EMC87593.1 - 0.01 15.3 0.0 6 6.3 0.0 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EMC87593.1 - 0.012 15.5 0.2 0.082 12.8 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.22 EMC87593.1 - 0.083 12.3 0.0 9.6 5.5 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain IIGP PF05049.8 EMC87593.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 EMC87593.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EMC87593.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC87593.1 - 0.15 12.5 0.1 0.35 11.3 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein ECH PF00378.15 EMC87594.1 - 4.6e-53 179.8 0.1 5.2e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 EMC87595.1 - 2.7e-48 164.4 0.1 5.8e-48 163.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87595.1 - 4.8e-33 114.3 0.0 1.2e-32 112.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.3 EMC87595.1 - 6.5e-15 54.6 2.7 6.5e-15 54.6 1.9 2.3 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain Kdo PF06293.9 EMC87595.1 - 8.2e-05 21.7 0.0 0.00021 20.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC87595.1 - 0.0028 17.4 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC87595.1 - 0.0093 15.3 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pep_M12B_propep PF01562.14 EMC87596.1 - 1.9e-36 124.7 0.1 3e-36 124.1 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 EMC87596.1 - 2e-23 82.4 31.0 2e-23 82.4 21.5 3.9 3 1 0 3 3 3 1 Disintegrin Reprolysin PF01421.14 EMC87596.1 - 7.5e-23 81.1 3.6 4.3e-16 59.1 0.2 2.5 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC87596.1 - 5.8e-22 77.9 5.9 5.8e-22 77.9 4.1 3.6 3 2 0 3 3 3 1 ADAM cysteine-rich Reprolysin_2 PF13574.1 EMC87596.1 - 4.5e-08 33.3 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC87596.1 - 8.6e-08 32.3 0.1 3.8e-06 26.9 0.1 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMC87596.1 - 2.3e-06 27.2 0.0 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMC87596.1 - 0.00044 20.7 0.1 0.0011 19.5 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC87596.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin MRI PF15325.1 EMC87596.1 - 0.072 14.0 0.1 0.16 12.9 0.1 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Spc97_Spc98 PF04130.8 EMC87597.1 - 4.6e-125 418.0 12.0 7.5e-125 417.2 8.3 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family NUDIX PF00293.23 EMC87599.1 - 1.6e-15 56.9 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EMC87599.1 - 2e-12 47.3 0.0 3.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EMC87599.1 - 1.3e-09 37.3 0.2 2.4e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain P4Ha_N PF08336.6 EMC87600.1 - 9.7e-45 151.6 0.1 2.3e-44 150.4 0.1 1.6 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 EMC87600.1 - 9.5e-13 48.2 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMC87600.1 - 1.7e-06 28.4 0.0 4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.12 EMC87600.1 - 0.00022 20.8 2.1 0.0006 19.5 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC87600.1 - 0.0012 18.6 1.2 0.011 15.6 0.8 2.5 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EMC87600.1 - 0.0079 16.7 0.9 0.024 15.2 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_18 PF13512.1 EMC87600.1 - 0.021 14.8 0.7 0.045 13.7 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC87600.1 - 0.035 14.0 1.6 0.083 12.8 1.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC87600.1 - 0.04 14.0 0.8 0.27 11.3 0.2 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EMC87600.1 - 0.088 12.4 1.0 0.32 10.6 0.5 1.9 1 1 1 2 2 2 0 TPR repeat PLA2G12 PF06951.6 EMC87601.1 - 1e-89 299.1 8.3 1.2e-89 298.8 5.7 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Zona_pellucida PF00100.18 EMC87602.1 - 5.7e-45 153.8 0.2 5.7e-45 153.8 0.1 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain FXa_inhibition PF14670.1 EMC87602.1 - 4.8e-18 64.9 30.0 4.3e-11 42.7 7.6 4.8 6 0 0 6 6 6 2 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC87602.1 - 3.7e-05 23.2 16.8 0.006 16.1 0.3 4.3 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_3 PF12947.2 EMC87602.1 - 0.02 14.8 6.0 0.02 14.8 4.1 4.6 5 0 0 5 5 5 0 EGF domain DUF607 PF04678.8 EMC87603.1 - 4e-48 163.7 4.1 5.3e-45 153.5 2.8 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF607 DUF2960 PF11173.3 EMC87603.1 - 0.018 15.3 0.1 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) WD40 PF00400.27 EMC87604.1 - 1.7e-23 81.5 13.7 9.6e-09 34.8 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EMC87604.1 - 0.00011 21.8 0.2 0.00023 20.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC87604.1 - 0.008 15.8 0.1 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EMC87604.1 - 0.012 13.7 0.3 0.13 10.3 0.1 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 p450 PF00067.17 EMC87605.1 - 9.4e-126 420.0 0.0 1.1e-125 419.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.13 EMC87606.1 - 1.7e-48 165.1 2.8 3e-48 164.3 1.9 1.4 1 0 0 1 1 1 1 BAR domain RhoGAP PF00620.22 EMC87606.1 - 4.7e-46 156.1 0.1 2.6e-45 153.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DUF2935 PF11155.3 EMC87606.1 - 0.12 12.5 0.4 0.83 9.7 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) UCH PF00443.24 EMC87607.1 - 5.4e-11 42.0 0.0 5.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC87607.1 - 8.6e-08 31.9 0.0 1e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin PF00301.15 EMC87607.1 - 0.064 13.1 0.4 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Rubredoxin Homeobox PF00046.24 EMC87609.1 - 7e-23 80.0 7.6 7e-23 80.0 5.2 1.7 2 0 0 2 2 2 1 Homeobox domain Terminase_5 PF06056.7 EMC87609.1 - 0.036 13.6 0.1 0.086 12.4 0.1 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trep_dent_lipo PF09710.5 EMC87609.1 - 0.055 12.1 1.0 0.07 11.7 0.7 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) FA_hydroxylase PF04116.8 EMC87610.1 - 1.1e-19 70.9 14.2 1.1e-19 70.9 9.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily F-box-like PF12937.2 EMC87611.1 - 1.4e-08 34.2 3.0 2.6e-08 33.4 0.5 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EMC87611.1 - 2.2e-08 33.5 2.6 2.6e-08 33.2 0.1 2.5 3 0 0 3 3 3 1 F-box domain DUF4116 PF13475.1 EMC87611.1 - 0.008 15.6 0.4 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) CLN5 PF15014.1 EMC87612.1 - 7.6e-178 590.2 4.8 8.5e-178 590.1 3.3 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Lipase3_N PF03893.11 EMC87612.1 - 0.047 13.5 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Lipase 3 N-terminal region EIIA-man PF03610.11 EMC87612.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component DJ-1_PfpI PF01965.19 EMC87613.1 - 2.5e-12 46.4 0.8 3.6e-12 45.9 0.5 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family MmgE_PrpD PF03972.9 EMC87614.1 - 5.6e-65 219.2 0.0 6.5e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PDZ PF00595.19 EMC87617.1 - 3.9e-09 36.5 0.0 1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 EMC87617.1 - 1.5e-06 28.1 8.8 3.2e-06 27.1 6.1 1.6 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 EMC87617.1 - 8.6e-06 25.5 0.0 2.5e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_C12 PF01088.16 EMC87618.1 - 6.1e-80 267.4 0.0 6.8e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LMP PF04778.7 EMC87618.1 - 0.067 12.9 0.5 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 LMP repeated region HCaRG PF07258.9 EMC87619.1 - 6.9e-24 84.3 0.0 7.6e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein Lipase_GDSL_2 PF13472.1 EMC87620.1 - 2.4e-07 31.0 0.0 5.7e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMC87620.1 - 0.026 14.3 0.0 0.069 12.9 0.0 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase zf-C2H2 PF00096.21 EMC87621.1 - 2.8e-14 52.4 22.9 9.7e-06 25.6 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC87621.1 - 2.6e-11 43.2 8.9 9.7e-08 31.9 1.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC87621.1 - 2.1e-07 30.7 20.5 0.0093 16.2 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMC87621.1 - 0.021 15.0 3.6 2.6 8.3 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC87621.1 - 0.13 12.4 4.0 4.7 7.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC87621.1 - 2.6 8.0 7.5 0.48 10.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC87623.1 - 1.8e-15 56.2 20.5 7e-06 26.0 1.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC87623.1 - 2.8e-12 46.2 6.9 2.2e-07 30.7 0.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC87623.1 - 7.9e-11 41.5 19.8 0.00062 19.9 1.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMC87623.1 - 0.0016 18.5 6.2 0.039 14.1 0.5 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EMC87623.1 - 0.003 17.6 10.5 0.17 12.1 0.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain IBR PF01485.16 EMC87623.1 - 0.19 11.5 4.3 1 9.2 3.0 2.1 1 1 0 1 1 1 0 IBR domain zf-C2H2_6 PF13912.1 EMC87623.1 - 0.93 9.4 4.3 0.45 10.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EMC87623.1 - 1.8 8.3 10.0 4.4 7.1 0.9 2.6 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 EMC87623.1 - 8.8 6.6 11.3 3.5 7.8 0.1 3.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Reo_sigmaC PF04582.7 EMC87624.1 - 0.12 11.4 18.8 0.038 13.1 2.2 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein RNB PF00773.14 EMC87625.1 - 2.6e-94 316.1 2.6 3.9e-94 315.5 0.1 2.1 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 EMC87625.1 - 2e-08 34.4 1.0 6.7e-08 32.7 0.7 1.9 1 0 0 1 1 1 1 PIN domain BORA_N PF15280.1 EMC87626.1 - 3.7e-63 212.7 4.0 3.7e-63 212.7 2.7 2.0 2 0 0 2 2 2 1 Protein aurora borealis N-terminus MOZART1 PF12554.3 EMC87627.1 - 3.4e-23 80.8 0.3 3.9e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Yae1_N PF09811.4 EMC87628.1 - 3.2e-14 52.1 42.8 0.098 12.2 1.7 4.5 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Kelch_1 PF01344.20 EMC87629.1 - 2.3e-57 190.2 12.0 8e-16 57.3 0.0 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 EMC87629.1 - 1.3e-36 123.2 7.3 1.1e-10 41.2 0.0 5.4 2 2 3 5 5 5 5 Kelch motif BACK PF07707.10 EMC87629.1 - 2e-33 114.2 0.1 5.3e-33 112.9 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 EMC87629.1 - 1.7e-29 102.0 0.4 4.4e-29 100.7 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 EMC87629.1 - 6.8e-21 73.1 10.8 7.8e-07 28.6 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EMC87629.1 - 1.8e-20 72.4 9.1 6.1e-07 29.1 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC87629.1 - 5.9e-17 61.3 5.8 1.5e-05 25.0 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC87629.1 - 3.5e-08 33.2 3.9 0.023 14.6 0.0 5.3 5 0 0 5 5 5 1 Kelch motif HARP PF07443.8 EMC87629.1 - 1.9 7.9 5.5 35 3.8 0.0 3.8 4 0 0 4 4 4 0 HepA-related protein (HARP) bZIP_1 PF00170.16 EMC87630.1 - 0.0014 18.5 10.7 0.0014 18.5 7.4 5.4 1 1 5 6 6 6 2 bZIP transcription factor CCDC155 PF14662.1 EMC87630.1 - 0.0024 17.4 58.5 0.0037 16.8 17.9 2.4 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 DUF2968 PF11180.3 EMC87630.1 - 0.0029 17.0 18.0 0.0029 17.0 12.5 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF2968) GAGA_bind PF06217.7 EMC87630.1 - 0.018 15.0 27.6 0.35 10.7 5.4 3.0 1 1 2 3 3 3 0 GAGA binding protein-like family DivIC PF04977.10 EMC87630.1 - 0.066 12.7 55.8 0.13 11.7 6.0 5.0 1 1 4 5 5 5 0 Septum formation initiator DUF2353 PF09789.4 EMC87630.1 - 0.082 12.1 36.7 0.59 9.3 11.2 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF904 PF06005.7 EMC87630.1 - 0.17 12.2 69.0 6.9 7.0 12.7 5.3 1 1 4 5 5 5 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 EMC87630.1 - 0.19 12.2 41.7 0.068 13.6 5.4 4.2 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EMC87630.1 - 0.31 10.6 58.1 0.22 11.1 20.4 2.8 1 1 2 3 3 3 0 IncA protein HALZ PF02183.13 EMC87630.1 - 0.73 9.5 54.3 0.54 10.0 4.2 6.8 3 1 4 7 7 7 0 Homeobox associated leucine zipper DUF972 PF06156.8 EMC87630.1 - 1.5 9.2 46.6 54 4.2 9.7 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Sbi-IV PF11621.3 EMC87630.1 - 2.3 8.4 23.2 1.5 9.0 4.3 3.5 2 2 2 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI bZIP_Maf PF03131.12 EMC87630.1 - 4 7.7 45.0 1.9 8.8 2.5 4.4 1 1 3 4 4 4 0 bZIP Maf transcription factor APG6 PF04111.7 EMC87630.1 - 6.4 5.7 60.6 2.1 7.3 14.6 2.9 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF3888 PF13027.1 EMC87633.1 - 0.019 14.7 0.0 0.047 13.5 0.0 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3888) RVT_1 PF00078.22 EMC87633.1 - 0.088 12.1 0.3 0.38 10.0 0.1 1.8 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.12 EMC87635.1 - 1.1e-89 294.8 0.0 1.2e-19 70.3 0.0 6.7 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 EMC87635.1 - 4.9e-09 35.6 0.0 0.18 11.3 0.0 5.2 5 0 0 5 5 5 3 Cadherin-like DUF1767 PF08585.7 EMC87636.1 - 1.5e-17 63.6 0.0 3.8e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) SMN PF06003.7 EMC87636.1 - 1.4e-10 40.6 0.0 1.4e-10 40.6 0.0 2.5 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) UBA PF00627.26 EMC87636.1 - 2.8e-10 39.7 0.5 7.1e-10 38.4 0.2 1.8 2 0 0 2 2 2 1 UBA/TS-N domain TUDOR PF00567.19 EMC87636.1 - 3.2e-10 39.8 0.0 8.1e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Tudor domain HBS1_N PF08938.5 EMC87636.1 - 0.031 14.3 0.7 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 HBS1 N-terminus UBA_4 PF14555.1 EMC87636.1 - 0.11 12.0 0.2 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain RhoGAP PF00620.22 EMC87637.1 - 8e-18 64.4 1.5 2.1e-15 56.6 0.5 2.4 2 0 0 2 2 2 2 RhoGAP domain Drf_GBD PF06371.8 EMC87638.1 - 1.1e-21 77.0 2.3 1.5e-21 76.6 1.6 1.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Closter_coat PF01785.12 EMC87638.1 - 0.031 13.3 0.3 0.039 12.9 0.2 1.1 1 0 0 1 1 1 0 Closterovirus coat protein FH2 PF02181.18 EMC87639.1 - 1.2e-107 360.0 27.6 1.2e-107 360.0 19.1 3.6 3 2 2 5 5 5 2 Formin Homology 2 Domain Drf_FH3 PF06367.11 EMC87639.1 - 1.3e-57 194.4 3.5 1.3e-57 194.4 2.4 4.0 4 1 1 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EMC87639.1 - 3e-24 85.4 0.2 3e-24 85.4 0.1 3.3 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_DAD PF06345.6 EMC87639.1 - 2.7e-08 33.1 2.7 6.5e-08 31.9 1.9 1.7 1 0 0 1 1 1 1 DRF Autoregulatory Domain Cadherin PF00028.12 EMC87640.1 - 8.4e-92 301.6 0.0 1.1e-17 64.0 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 EMC87640.1 - 1.6e-16 59.6 0.1 5.6e-09 35.4 0.0 4.5 5 0 0 5 5 5 2 Cadherin-like BRICHOS PF04089.9 EMC87642.1 - 3.4e-28 97.3 0.0 6.4e-28 96.4 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain SGS PF05002.10 EMC87643.1 - 3.6e-29 100.3 2.6 3.6e-29 100.3 1.8 2.1 2 0 0 2 2 2 1 SGS domain CS PF04969.11 EMC87643.1 - 2.7e-20 72.6 2.1 6.6e-20 71.4 1.5 1.7 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EMC87643.1 - 1.4e-12 47.0 5.9 6.8e-09 35.2 1.5 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMC87643.1 - 7.3e-10 38.0 8.4 6e-06 25.6 2.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMC87643.1 - 1.5e-09 37.0 8.2 7.4e-06 25.4 1.9 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87643.1 - 1.5e-08 34.2 3.2 0.00028 20.8 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87643.1 - 1.3e-05 25.6 2.4 5.4e-05 23.7 0.7 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87643.1 - 0.00043 20.6 1.5 0.048 14.3 0.4 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC87643.1 - 0.0079 16.0 2.0 0.071 12.9 0.3 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC87643.1 - 0.0085 16.2 3.3 0.32 11.1 0.1 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMC87643.1 - 0.02 15.2 2.9 0.23 11.8 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMC87643.1 - 0.021 14.9 2.9 0.062 13.4 0.6 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87643.1 - 0.024 14.4 5.0 0.65 9.9 1.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMC87643.1 - 0.12 12.3 3.5 0.28 11.1 2.1 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC87643.1 - 0.59 10.0 4.8 8.5 6.3 0.5 2.9 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Elf-1_N PF12310.3 EMC87644.1 - 8.2e-47 157.6 5.0 2.2e-46 156.2 3.5 1.8 1 0 0 1 1 1 1 Transcription factor protein N terminal Ets PF00178.17 EMC87644.1 - 2.7e-35 120.3 2.4 4.4e-35 119.6 1.6 1.3 1 0 0 1 1 1 1 Ets-domain WW PF00397.21 EMC87645.1 - 8.8e-18 63.8 23.4 2.3e-09 36.9 4.3 3.0 3 0 0 3 3 3 2 WW domain zf-U1 PF06220.7 EMC87645.1 - 2.8e-14 52.3 0.9 4.4e-14 51.7 0.6 1.3 1 0 0 1 1 1 1 U1 zinc finger PQQ PF01011.16 EMC87645.1 - 0.021 14.3 0.1 0.69 9.5 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat RF-1 PF00472.15 EMC87646.1 - 2e-39 133.9 2.2 5.1e-39 132.6 1.5 1.7 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EMC87646.1 - 1.6e-29 101.9 0.0 1.6e-29 101.9 0.0 2.8 2 1 2 4 4 4 1 PCRF domain CDI PF02234.14 EMC87646.1 - 0.097 12.4 1.1 0.42 10.4 0.0 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor HisKA PF00512.20 EMC87646.1 - 0.33 10.9 6.9 1.4 8.9 0.4 3.4 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain zf-C4pol PF14260.1 EMC87646.1 - 1.1 9.3 4.7 1.1 9.3 0.2 2.9 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF4635 PF15466.1 EMC87646.1 - 5.8 6.2 10.0 18 4.6 1.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) NARP1 PF12569.3 EMC87647.1 - 1.6e-214 713.4 21.1 1.6e-214 713.4 14.6 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EMC87647.1 - 1.8e-16 59.5 24.0 3.7e-07 29.6 0.3 7.9 6 2 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 EMC87647.1 - 5.3e-15 54.0 23.6 3.5e-05 23.3 0.1 8.1 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87647.1 - 8.3e-14 51.6 12.1 0.01 16.1 0.1 6.3 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87647.1 - 1.4e-13 50.1 0.5 0.17 12.6 0.0 8.7 7 1 2 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87647.1 - 5.6e-11 42.8 12.4 0.0017 19.0 0.0 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC87647.1 - 6e-11 42.1 13.9 0.042 13.7 0.1 7.3 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMC87647.1 - 4.3e-10 38.7 32.0 1.6e-05 24.3 0.4 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EMC87647.1 - 7.6e-07 29.1 22.9 0.00068 19.7 0.3 6.5 4 3 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMC87647.1 - 1.8e-06 27.2 27.1 0.0014 18.3 0.2 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMC87647.1 - 9.1e-05 21.6 2.3 9.1e-05 21.6 1.6 3.7 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC87647.1 - 0.00013 21.4 12.6 0.011 15.5 0.1 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.13 EMC87647.1 - 0.00099 18.9 4.4 0.035 13.9 0.0 4.2 3 2 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 EMC87647.1 - 0.0028 17.4 8.2 0.28 11.0 0.3 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC87647.1 - 0.0087 15.9 3.1 27 4.8 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC87647.1 - 0.032 14.6 10.7 20 5.9 0.1 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMC87647.1 - 0.13 12.7 0.0 2.5e+02 2.5 0.1 4.4 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87647.1 - 0.2 11.9 22.7 3.2 8.1 0.0 8.0 10 0 0 10 10 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC87647.1 - 1 9.3 22.4 8.1 6.4 0.1 6.6 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EMC87647.1 - 3.9 7.3 18.8 0.43 10.4 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DAGK_acc PF00609.14 EMC87648.1 - 5.7e-54 182.6 0.0 1.2e-53 181.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EMC87648.1 - 2.7e-29 101.2 0.0 7.9e-29 99.7 0.0 1.9 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EMC87648.1 - 1.6e-19 69.3 25.7 1e-10 41.1 3.9 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 EMC87648.1 - 2.5e-18 66.2 1.1 7.6e-18 64.6 0.8 1.9 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 EMC87648.1 - 2.1e-17 62.7 0.2 6.6e-17 61.1 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC87648.1 - 7.6e-16 58.0 0.5 1.7e-15 56.9 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EMC87648.1 - 5.2e-06 26.6 6.2 2e-05 24.8 1.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EMC87648.1 - 0.00015 21.7 0.3 0.00032 20.7 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C1_3 PF07649.7 EMC87648.1 - 0.001 19.0 2.7 0.001 19.0 1.8 2.8 2 0 0 2 2 2 1 C1-like domain Mcp5_PH PF12814.2 EMC87648.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology TNF PF00229.13 EMC87650.1 - 9.4e-30 102.7 0.9 1.4e-29 102.1 0.6 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Cytomega_US3 PF05963.6 EMC87651.1 - 0.098 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus US3 protein NAD_binding_1 PF00175.16 EMC87651.1 - 0.12 12.9 3.7 2.2 8.8 0.4 2.4 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain DnaJ PF00226.26 EMC87652.1 - 3.4e-10 39.5 0.0 5.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EMC87652.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EMC87652.1 - 1 8.7 3.6 0.44 9.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) DUF464 PF04327.7 EMC87653.1 - 0.13 12.5 4.6 0.65 10.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF464) CENP-F_leu_zip PF10473.4 EMC87653.1 - 0.14 12.0 42.1 0.63 9.9 8.5 3.9 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fer4_12 PF13353.1 EMC87653.1 - 1.1 9.3 5.3 4.1 7.5 0.2 3.3 2 2 2 4 4 4 0 4Fe-4S single cluster domain Atg14 PF10186.4 EMC87653.1 - 6.6 5.5 32.2 1.8 7.4 12.5 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 EMC87653.1 - 8.7 6.1 6.9 4.7 7.0 0.9 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EMC87653.1 - 9.2 5.8 39.0 0.7 9.4 2.4 3.3 1 1 2 3 3 3 0 IncA protein Cu-oxidase_4 PF02578.10 EMC87654.1 - 7.2e-62 208.5 0.0 9.2e-62 208.1 0.0 1.1 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase TSC22 PF01166.13 EMC87655.1 - 3.7e-31 106.8 4.1 3.7e-31 106.8 2.8 2.2 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF972 PF06156.8 EMC87655.1 - 0.003 17.8 1.9 0.0087 16.3 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Nucleocap_ssRNA PF11128.3 EMC87655.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid bZIP_2 PF07716.10 EMC87655.1 - 0.94 9.3 5.0 2 8.2 3.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 EMC87655.1 - 1.4 8.9 3.2 2.7 7.9 2.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor NUFIP1 PF10453.4 EMC87656.1 - 3e-21 74.6 5.2 3e-21 74.6 3.6 2.5 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 EMC87656.1 - 0.00012 22.1 4.2 0.00028 20.9 2.9 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMC87656.1 - 0.25 11.7 1.6 0.82 10.1 1.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3752 PF12572.3 EMC87657.1 - 5.3e-15 55.8 3.5 5.3e-15 55.8 2.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) TFIIF_beta PF02270.10 EMC87658.1 - 3e-86 289.6 7.6 4.7e-85 285.7 5.3 1.9 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Wound_ind PF08186.6 EMC87658.1 - 0.023 14.6 1.7 0.29 11.0 0.0 2.7 3 0 0 3 3 3 0 Wound-inducible basic protein family BTB_2 PF02214.17 EMC87659.1 - 5.8e-18 64.8 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Mito_carr PF00153.22 EMC87660.1 - 3.3e-70 231.8 0.5 1.8e-24 85.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 EMC87661.1 - 7.5e-74 246.6 7.2 7.5e-74 246.6 5.0 3.9 5 0 0 5 5 5 1 Sec34-like family CLTH PF10607.4 EMC87661.1 - 0.025 14.2 5.8 0.025 14.2 1.1 3.0 2 1 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Laminin_I PF06008.9 EMC87661.1 - 0.026 13.8 0.5 0.026 13.8 0.3 3.1 4 0 0 4 4 4 0 Laminin Domain I PP2C_C PF07830.8 EMC87661.1 - 0.12 12.4 0.6 1.4 9.0 0.1 2.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Aha1_N PF09229.6 EMC87661.1 - 0.18 11.6 2.4 0.38 10.5 0.2 2.7 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal NPV_P10 PF05531.7 EMC87661.1 - 0.23 11.7 4.7 4.8 7.4 0.1 4.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EMC87661.1 - 4.7 7.4 11.1 4.4 7.5 0.5 4.5 4 2 0 4 4 4 0 Syntaxin FAM194 PF14977.1 EMC87662.1 - 8.5e-55 184.9 0.0 9.3e-55 184.8 0.0 1.0 1 0 0 1 1 1 1 FAM194 protein MORN PF02493.15 EMC87662.1 - 0.0027 17.3 2.5 0.064 13.0 0.3 2.6 2 0 0 2 2 2 1 MORN repeat MORN_2 PF07661.8 EMC87662.1 - 0.13 12.3 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 MORN repeat variant DASH_Spc34 PF08657.5 EMC87664.1 - 0.00072 19.3 7.4 0.001 18.7 5.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 Chibby PF14645.1 EMC87664.1 - 0.37 10.6 5.0 9.7 6.1 0.4 2.8 2 0 0 2 2 2 0 Chibby family ABC2_membrane_3 PF12698.2 EMC87664.1 - 0.52 9.3 1.4 0.6 9.0 1.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MecA PF05389.7 EMC87664.1 - 0.53 9.7 6.8 0.76 9.2 4.4 1.4 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) HALZ PF02183.13 EMC87664.1 - 1.1 9.0 9.6 5 6.9 0.1 3.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF972 PF06156.8 EMC87664.1 - 7.5 6.9 12.5 5.1 7.4 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Sina PF03145.11 EMC87665.1 - 3.5e-36 124.7 0.1 5.6e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family Peptidase_M14 PF00246.19 EMC87666.1 - 1.2e-83 280.9 0.0 1.6e-83 280.5 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMC87666.1 - 4.1e-13 48.8 0.8 1e-12 47.4 0.5 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF1642 PF07852.6 EMC87666.1 - 0.0041 17.4 0.6 0.031 14.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1642) DUF2011 PF09428.5 EMC87666.1 - 5.7 6.8 7.7 4.2 7.2 0.0 2.8 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF2011) LRR_8 PF13855.1 EMC87667.1 - 8.2e-24 83.1 11.3 4e-09 36.0 1.4 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC87667.1 - 2.3e-23 81.3 14.6 1.2e-07 31.1 0.2 5.8 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC87667.1 - 2.8e-17 60.0 14.9 0.02 14.8 0.4 9.1 8 0 0 8 8 8 5 Leucine Rich Repeat CH PF00307.26 EMC87667.1 - 3.7e-11 43.0 0.0 9.6e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 EMC87667.1 - 1.7e-10 39.3 12.8 0.48 10.8 0.2 8.0 7 0 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 EMC87667.1 - 7.5e-07 28.5 10.6 0.95 9.7 0.2 7.5 9 0 0 9 9 9 2 Leucine Rich repeat CAMSAP_CH PF11971.3 EMC87667.1 - 8.8e-05 22.0 0.0 0.00032 20.2 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 EMC87667.1 - 0.00064 19.7 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin RVT_1 PF00078.22 EMC87668.1 - 0.043 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.16 EMC87669.1 - 3e-72 242.8 13.2 4.2e-72 242.3 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87669.1 - 3.3e-16 59.2 17.0 5.4e-16 58.5 11.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC87669.1 - 2.9e-06 26.5 7.8 2.9e-06 26.5 5.4 3.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1385 PF07136.6 EMC87669.1 - 0.47 9.4 7.5 0.15 11.0 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1385) ATP-grasp_2 PF08442.5 EMC87670.1 - 4.6e-75 251.4 0.6 6.4e-75 250.9 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EMC87670.1 - 2.3e-26 92.2 2.5 3.9e-26 91.4 1.7 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EMC87670.1 - 5.7e-10 38.7 0.5 1.1e-09 37.8 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EMC87670.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.14 EMC87670.1 - 0.046 13.2 0.4 0.14 11.7 0.3 1.7 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HipA_N PF07805.7 EMC87670.1 - 0.076 13.2 0.0 0.3 11.3 0.0 2.0 1 0 0 1 1 1 0 HipA-like N-terminal domain nsp7 PF08716.5 EMC87670.1 - 0.21 12.0 1.6 4.7 7.6 0.2 2.6 2 1 0 2 2 2 0 nsp7 replicase BRICHOS PF04089.9 EMC87671.1 - 4.3e-28 97.0 0.0 7.1e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 BRICHOS domain RB_A PF01858.12 EMC87672.1 - 7.6e-82 273.6 1.5 1.1e-81 273.2 0.2 1.9 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain Rb_C PF08934.5 EMC87672.1 - 6.2e-78 259.7 3.8 6.2e-78 259.7 2.7 2.6 3 0 0 3 3 3 1 Rb C-terminal domain RB_B PF01857.15 EMC87672.1 - 1.1e-38 131.8 4.6 3.7e-38 130.0 3.2 2.0 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.3 EMC87672.1 - 8e-33 112.7 4.9 4.3e-30 103.8 2.7 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3452) 7tm_1 PF00001.16 EMC87673.1 - 7.2e-60 202.2 29.3 7.2e-60 202.2 20.3 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC87673.1 - 6.3e-05 22.2 20.4 6.3e-05 22.2 14.1 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RCC1 PF00415.13 EMC87674.1 - 4.8e-65 215.5 23.3 7.4e-16 58.1 0.9 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC87674.1 - 1.8e-31 107.0 25.0 2.8e-11 42.6 0.8 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EMC87674.1 - 2.2e-20 72.6 1.3 1.2e-17 63.8 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 EMC87674.1 - 1.3e-05 25.0 2.4 0.00077 19.2 0.2 3.1 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.1 EMC87674.1 - 0.036 14.2 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) CBM_X PF06204.6 EMC87674.1 - 3.2 7.2 12.0 12 5.4 0.1 4.6 5 0 0 5 5 5 0 Putative carbohydrate binding domain Kelch_2 PF07646.10 EMC87674.1 - 5.4 6.9 8.7 13 5.7 0.1 4.7 5 0 0 5 5 5 0 Kelch motif 7tm_1 PF00001.16 EMC87675.1 - 3.6e-50 170.4 26.1 4.8e-50 170.0 18.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC87675.1 - 2.2e-05 23.7 16.5 2.2e-05 23.7 11.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC87675.1 - 3.4e-05 23.0 22.0 3.4e-05 23.0 15.3 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 EMC87675.1 - 0.00014 21.7 12.9 0.00014 21.7 8.9 2.5 1 1 1 2 2 2 1 Olfactory receptor TAS2R PF05296.8 EMC87675.1 - 0.0023 16.8 25.5 0.0064 15.4 17.7 1.6 1 1 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) DUF3382 PF11862.3 EMC87675.1 - 0.17 11.8 2.4 0.97 9.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) fn3 PF00041.16 EMC87676.1 - 1.5e-90 297.4 0.0 4.6e-11 42.7 0.0 9.8 9 1 0 9 9 9 9 Fibronectin type III domain SusE PF14292.1 EMC87676.1 - 4.8e-08 32.8 0.1 2.2 8.1 0.0 6.6 7 0 0 7 7 7 3 SusE outer membrane protein IL6Ra-bind PF09240.5 EMC87676.1 - 0.011 15.8 2.8 3.3 7.9 0.2 2.7 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding DUF912 PF06024.7 EMC87676.1 - 0.058 13.4 0.2 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_1 PF00001.16 EMC87677.1 - 5.2e-29 101.1 3.9 5.6e-29 101.0 2.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC87677.1 - 1.1e-05 24.7 0.7 1.1e-05 24.6 0.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC87677.1 - 0.0028 16.8 1.7 0.0034 16.5 1.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.16 EMC87678.1 - 1.8e-18 66.6 1.7 2.1e-18 66.3 1.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC87678.1 - 6.1e-10 38.7 0.2 7.5e-10 38.4 0.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 EMC87678.1 - 1.3e-06 27.8 1.4 1.6e-06 27.4 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Herpes_US9 PF06072.6 EMC87678.1 - 0.37 10.6 1.8 0.39 10.5 0.1 1.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Sigma_reg_N PF13800.1 EMC87678.1 - 0.61 10.1 3.2 1.5 8.9 0.3 2.3 1 1 1 2 2 2 0 Sigma factor regulator N-terminal dCMP_cyt_deam_1 PF00383.17 EMC87679.1 - 7e-18 64.1 0.5 7.2e-09 35.2 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Mo25 PF08569.6 EMC87680.1 - 1.6e-139 464.6 14.0 1.8e-139 464.4 9.7 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 EMC87680.1 - 0.0081 16.4 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats UME PF08064.8 EMC87680.1 - 0.25 11.2 4.2 0.27 11.2 0.1 2.9 2 2 2 4 4 4 0 UME (NUC010) domain DUF544 PF04424.8 EMC87680.1 - 0.91 9.3 4.1 2.3 8.0 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF544) zf-HC5HC2H PF13771.1 EMC87682.1 - 2.6e-15 56.3 4.2 2.6e-15 56.3 2.9 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC87682.1 - 1.6e-06 28.0 8.5 1.1e-05 25.4 5.6 2.3 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 EMC87682.1 - 0.0011 18.5 11.9 0.032 13.8 6.2 2.7 2 1 0 2 2 2 2 PHD-finger RCC1 PF00415.13 EMC87683.1 - 7.1e-65 215.0 24.4 4.2e-16 58.8 1.5 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC87683.1 - 8.2e-33 111.3 31.6 2.8e-10 39.5 0.1 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EMC87683.1 - 4e-22 78.2 0.6 4.2e-20 71.7 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 EMC87683.1 - 5.1e-06 26.2 1.0 0.0084 15.9 0.1 3.1 2 1 0 2 2 2 2 BTB And C-terminal Kelch SUKH-3 PF14433.1 EMC87683.1 - 0.036 13.8 0.6 2.3 7.9 0.0 3.4 3 0 0 3 3 3 0 SUKH-3 immunity protein PQQ_3 PF13570.1 EMC87683.1 - 1.1 9.6 5.4 12 6.2 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain Arf PF00025.16 EMC87684.1 - 3.5e-50 169.6 0.0 4.4e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMC87684.1 - 5e-11 42.2 0.0 6.2e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMC87684.1 - 1.2e-10 40.6 0.0 4.7e-08 32.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMC87684.1 - 8.6e-09 34.8 0.0 1.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMC87684.1 - 6.2e-08 33.1 0.0 8.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EMC87684.1 - 4.7e-07 29.1 0.0 5.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC87684.1 - 0.00011 22.1 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMC87684.1 - 0.041 12.9 0.0 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Arm PF00514.18 EMC87685.1 - 4e-86 280.2 16.9 3.2e-13 48.9 0.3 9.7 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC87685.1 - 4.6e-23 81.2 0.1 6.5e-09 35.9 0.0 5.9 2 2 5 7 7 7 6 HEAT repeats HEAT PF02985.17 EMC87685.1 - 2.1e-18 64.6 7.9 0.0013 18.6 0.0 6.9 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.1 EMC87685.1 - 2.9e-18 65.7 1.9 2.5e-06 27.7 0.1 6.6 3 3 4 7 7 7 5 HEAT-like repeat Adaptin_N PF01602.15 EMC87685.1 - 4.8e-09 35.0 0.1 8.7e-09 34.2 0.1 1.3 1 1 0 1 1 1 1 Adaptin N terminal region IBB PF01749.15 EMC87685.1 - 3e-08 33.6 0.9 5.4e-08 32.9 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 EMC87685.1 - 7.3e-07 28.5 0.6 0.74 8.8 0.0 4.3 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.9 EMC87685.1 - 3e-05 23.3 0.4 0.0066 15.5 0.1 2.6 1 1 1 2 2 2 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EMC87685.1 - 5.1e-05 21.7 0.3 0.012 13.8 0.0 3.0 2 2 0 3 3 3 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 EMC87685.1 - 0.0004 20.2 0.5 6.5 6.7 0.0 4.2 4 1 1 5 5 5 1 V-ATPase subunit H Cnd3 PF12719.2 EMC87685.1 - 0.0099 14.8 0.1 1.3 7.8 0.0 3.4 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF1981 PF09324.5 EMC87685.1 - 0.02 14.3 0.7 0.59 9.7 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) Mo25 PF08569.6 EMC87685.1 - 0.022 13.8 0.1 0.063 12.2 0.0 1.8 1 0 0 1 1 1 0 Mo25-like RasGEF_N_2 PF14663.1 EMC87685.1 - 0.057 13.3 0.0 0.61 10.0 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RuvA_C PF07499.8 EMC87685.1 - 6.1 7.0 6.0 34 4.7 0.0 4.3 5 0 0 5 5 5 0 RuvA, C-terminal domain SPRY PF00622.23 EMC87687.1 - 2.7e-12 46.8 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain IMS_HHH PF11798.3 EMC87687.1 - 0.097 12.7 0.0 0.7 10.0 0.0 2.3 3 0 0 3 3 3 0 IMS family HHH motif zf-RING_2 PF13639.1 EMC87688.1 - 1.4e-08 34.4 10.2 1.4e-08 34.4 7.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.19 EMC87688.1 - 1.4e-08 34.4 1.6 1.4e-08 34.4 1.1 3.5 4 0 0 4 4 3 1 B-box zinc finger zf-C3HC4_2 PF13923.1 EMC87688.1 - 3e-08 33.5 11.0 3e-08 33.5 7.6 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC87688.1 - 3.3e-08 33.0 8.6 3.3e-08 33.0 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC87688.1 - 5.5e-07 29.1 7.0 5.5e-07 29.1 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87688.1 - 9.8e-07 28.4 8.5 9.8e-07 28.4 5.9 2.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC87688.1 - 1.8e-06 27.5 6.5 1.8e-06 27.5 4.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMC87688.1 - 1.9e-06 27.6 10.6 1.9e-06 27.6 7.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC87688.1 - 0.0065 16.0 8.9 0.026 14.1 6.2 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Herpes_IE2_3 PF03361.9 EMC87688.1 - 0.018 14.3 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 U-box PF04564.10 EMC87688.1 - 0.071 13.0 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 U-box domain ATP-synt_E_2 PF08112.6 EMC87688.1 - 0.11 12.5 1.7 0.95 9.5 0.2 2.7 1 1 1 2 2 2 0 ATP synthase epsilon subunit BTB_2 PF02214.17 EMC87689.1 - 1.1e-18 67.1 0.2 2.4e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4286 PF14114.1 EMC87689.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) RNase_H2-Ydr279 PF09468.5 EMC87691.1 - 2.7e-65 220.5 4.6 3.1e-65 220.3 3.2 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) FAM124 PF15067.1 EMC87693.1 - 2.2e-114 380.7 0.0 3e-114 380.3 0.0 1.2 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.15 EMC87694.1 - 2.8e-96 322.8 0.9 3.1e-96 322.7 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Propep_M14 PF02244.11 EMC87694.1 - 0.013 15.1 0.1 0.14 11.7 0.0 2.4 2 1 0 2 2 2 0 Carboxypeptidase activation peptide DTW PF03942.10 EMC87694.1 - 0.1 11.8 0.1 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 DTW domain WD40 PF00400.27 EMC87695.1 - 3.7e-27 93.1 16.8 1.5e-10 40.5 1.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat FYVE PF01363.16 EMC87695.1 - 2.2e-15 56.2 8.2 5.1e-15 55.1 5.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger Nucleoporin_N PF08801.6 EMC87695.1 - 2.2e-07 29.9 0.1 0.05 12.3 0.0 3.7 2 1 1 3 3 3 2 Nup133 N terminal like FYVE_2 PF02318.11 EMC87695.1 - 0.054 13.3 4.8 0.12 12.2 3.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.19 EMC87695.1 - 0.84 9.5 9.6 0.14 12.0 0.4 3.4 3 0 0 3 3 3 0 B-box zinc finger DiS_P_DiS PF06750.8 EMC87695.1 - 2.8 7.7 6.6 32 4.4 4.1 2.8 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain adh_short PF00106.20 EMC87696.1 - 8.4e-20 71.3 0.1 1.6e-19 70.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC87696.1 - 2.3e-10 40.4 0.1 4.7e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC87696.1 - 6e-08 32.4 0.1 7.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMC87696.1 - 6.3e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMC87696.1 - 2.3e-05 24.4 3.9 0.0012 18.9 1.7 2.9 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EMC87696.1 - 0.00016 20.9 0.1 0.015 14.4 0.0 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMC87696.1 - 0.01 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase IncA PF04156.9 EMC87698.1 - 0.0096 15.5 3.1 0.0096 15.5 2.1 1.8 2 0 0 2 2 2 1 IncA protein COG2 PF06148.6 EMC87698.1 - 0.016 15.0 0.6 0.03 14.2 0.4 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MscS_porin PF12795.2 EMC87698.1 - 0.018 14.3 2.6 0.018 14.3 1.8 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4618 PF15397.1 EMC87698.1 - 0.022 14.0 0.7 0.038 13.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CRM1_C PF08767.6 EMC87698.1 - 0.029 13.2 0.8 0.039 12.8 0.6 1.2 1 0 0 1 1 1 0 CRM1 C terminal DUF972 PF06156.8 EMC87698.1 - 0.065 13.5 4.2 0.11 12.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2353 PF09789.4 EMC87698.1 - 0.11 11.7 4.8 0.36 10.0 3.4 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TBCA PF02970.11 EMC87698.1 - 0.15 12.1 9.0 2.5 8.2 1.9 2.3 2 1 0 2 2 2 0 Tubulin binding cofactor A Borrelia_REV PF03978.8 EMC87698.1 - 0.17 11.6 2.7 1.9 8.2 0.6 2.0 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein Bul1_C PF04426.7 EMC87698.1 - 0.22 10.6 2.5 0.24 10.5 1.8 1.2 1 0 0 1 1 1 0 Bul1 C terminus LRS4 PF10422.4 EMC87698.1 - 0.4 9.9 2.8 0.68 9.2 1.9 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 bZIP_1 PF00170.16 EMC87698.1 - 0.7 9.9 5.1 3.2 7.7 0.7 2.8 2 1 0 2 2 2 0 bZIP transcription factor TBPIP PF07106.8 EMC87698.1 - 1.2 8.6 6.6 0.13 11.7 1.3 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3829 PF12889.2 EMC87698.1 - 1.6 7.8 6.4 0.088 11.9 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) APG6 PF04111.7 EMC87698.1 - 2.5 7.0 18.0 0.032 13.2 4.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Jnk-SapK_ap_N PF09744.4 EMC87698.1 - 2.9 7.8 9.5 0.19 11.7 1.7 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HMA PF00403.21 EMC87699.1 - 7.9e-76 250.1 1.1 5.8e-15 55.1 0.0 6.7 6 0 0 6 6 6 6 Heavy-metal-associated domain Hydrolase PF00702.21 EMC87699.1 - 1.4e-74 251.1 1.9 3.2e-74 249.9 1.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMC87699.1 - 4.3e-47 160.0 3.8 1.4e-46 158.3 2.6 2.0 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMC87699.1 - 2.2e-15 57.3 0.0 5.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC87699.1 - 3.8e-07 29.9 2.4 9.1e-05 22.1 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMC87699.1 - 0.00027 20.7 0.8 0.0075 16.1 0.1 3.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Toxin_63 PF15541.1 EMC87699.1 - 0.012 15.5 0.0 2.6 8.0 0.0 2.9 2 0 0 2 2 2 0 Putative toxin 63 RRM_3 PF08777.6 EMC87699.1 - 0.11 12.3 0.1 4 7.3 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif Glycos_transf_1 PF00534.15 EMC87700.1 - 2.7e-28 98.5 0.0 5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMC87700.1 - 2.5e-10 40.6 0.0 2.8e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMC87700.1 - 6.4e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMC87700.1 - 0.016 14.8 0.0 0.18 11.5 0.0 2.3 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Pkinase PF00069.20 EMC87701.1 - 2.8e-69 233.1 0.2 2.8e-69 233.1 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87701.1 - 2.1e-49 167.9 0.1 2.1e-49 167.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87701.1 - 1.5e-07 30.6 0.0 1.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 EMC87702.1 - 8.5e-68 228.3 0.1 1.3e-67 227.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87702.1 - 3.4e-45 154.1 0.0 5.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87702.1 - 3.5e-09 36.0 0.0 4.2e-08 32.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EMC87702.1 - 0.0057 16.4 0.0 2.2 7.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC87702.1 - 0.4 9.7 2.1 0.52 9.3 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EAP30 PF04157.11 EMC87703.1 - 1.2e-57 194.6 2.3 1.2e-57 194.6 1.6 1.4 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EMC87703.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DUF1448 PF07289.6 EMC87703.1 - 0.016 14.1 0.0 0.067 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1448) MA3 PF02847.12 EMC87703.1 - 0.026 14.2 0.9 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 MA3 domain RPW8 PF05659.6 EMC87703.1 - 0.064 12.8 1.1 0.11 11.9 0.8 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Glyco_transf_8 PF01501.15 EMC87703.1 - 0.067 12.5 0.1 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 8 Fib_alpha PF08702.5 EMC87703.1 - 0.081 13.0 0.6 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Glutaredoxin2_C PF04399.8 EMC87703.1 - 0.12 11.9 0.3 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF4319 PF14203.1 EMC87703.1 - 1.6 8.3 5.4 0.73 9.4 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) TSP_1 PF00090.14 EMC87704.1 - 1.6e-11 44.0 8.2 1.6e-11 44.0 5.7 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain Fibrinogen_C PF00147.13 EMC87705.1 - 1e-77 260.9 15.3 1.2e-77 260.7 10.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PTEN_C2 PF10409.4 EMC87706.1 - 5.2e-27 94.2 0.3 1e-26 93.2 0.2 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 EMC87706.1 - 1.1e-09 37.9 0.0 3.7e-09 36.2 0.0 1.8 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Ion_trans PF00520.26 EMC87706.1 - 4.3e-09 35.9 5.1 4.3e-09 35.9 3.6 1.7 2 0 0 2 2 2 1 Ion transport protein Y_phosphatase PF00102.22 EMC87706.1 - 4.1e-06 26.3 0.0 7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC87706.1 - 4.7e-05 23.4 0.0 9.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate PKD_channel PF08016.7 EMC87706.1 - 0.0035 15.8 4.4 0.0056 15.1 3.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel Y_phosphatase3 PF13350.1 EMC87706.1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Mito_carr PF00153.22 EMC87707.1 - 6.9e-64 211.6 5.8 1.2e-22 79.3 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MogR_DNAbind PF12181.3 EMC87707.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) MRP-S31 PF15433.1 EMC87708.1 - 7.6e-69 232.3 5.9 8.2e-69 232.2 4.1 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Fork_head PF00250.13 EMC87709.1 - 4.7e-07 29.7 0.4 9.5e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 Fork head domain NdhM PF10664.4 EMC87709.1 - 0.098 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M COG6 PF06419.6 EMC87710.1 - 5.6e-199 662.2 9.3 6.3e-199 662.1 6.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 BLOC1_2 PF10046.4 EMC87710.1 - 0.001 19.1 2.7 0.0039 17.3 1.9 2.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cast PF10174.4 EMC87710.1 - 0.0025 15.9 3.4 0.0039 15.3 2.3 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF972 PF06156.8 EMC87710.1 - 0.039 14.3 1.6 0.17 12.2 1.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Nup54 PF13874.1 EMC87710.1 - 0.14 11.8 4.8 0.075 12.7 0.8 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 EMC87710.1 - 0.37 10.3 10.3 0.031 13.8 3.1 2.1 2 0 0 2 2 2 0 IncA protein Syntaxin PF00804.20 EMC87710.1 - 1 9.5 6.7 1.2 9.3 2.4 2.6 1 1 2 3 3 3 0 Syntaxin ERM PF00769.14 EMC87710.1 - 1.9 7.9 10.9 0.089 12.3 3.0 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family L_HGMIC_fpl PF10242.4 EMC87711.1 - 1.7e-30 106.4 5.1 2e-30 106.1 3.5 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 EMC87711.1 - 0.00056 19.6 0.7 0.00056 19.6 0.5 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction UPF0016 PF01169.14 EMC87711.1 - 0.0096 16.0 1.2 0.0096 16.0 0.9 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0016 EI24 PF07264.6 EMC87711.1 - 0.12 11.8 1.4 0.15 11.4 1.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) L_HGMIC_fpl PF10242.4 EMC87712.1 - 3.1e-11 43.6 0.1 5.9e-11 42.6 0.1 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein NHL PF01436.16 EMC87713.1 - 2.2e-15 55.7 6.0 2e-07 30.6 0.1 5.4 5 1 0 5 5 5 3 NHL repeat SGL PF08450.7 EMC87713.1 - 0.00014 21.3 0.7 0.023 14.0 0.1 3.2 3 2 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Tachylectin PF14517.1 EMC87713.1 - 0.014 14.7 0.2 0.042 13.1 0.0 1.6 2 1 0 2 2 2 0 Tachylectin Proteasome_A_N PF10584.4 EMC87713.1 - 0.055 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF4476 PF14771.1 EMC87714.1 - 3.7e-22 78.1 0.2 5.7e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) Band_7 PF01145.20 EMC87715.1 - 7.2e-30 104.2 1.3 8.9e-30 103.9 0.9 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMC87715.1 - 0.012 15.1 0.1 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family A2M_comp PF07678.9 EMC87716.1 - 3.9e-72 242.4 2.8 6.8e-72 241.6 1.9 1.4 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 EMC87716.1 - 9.4e-34 114.8 0.3 3.5e-33 113.0 0.2 2.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 EMC87716.1 - 2.1e-25 89.0 2.0 5.2e-24 84.5 0.0 3.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M_recep PF07677.9 EMC87716.1 - 1.9e-24 85.6 0.2 3.2e-22 78.5 0.0 3.2 2 0 0 2 2 2 1 A-macroglobulin receptor NTR PF01759.16 EMC87716.1 - 3.1e-24 84.6 0.6 1e-23 82.9 0.4 2.0 1 0 0 1 1 1 1 UNC-6/NTR/C345C module A2M_N PF01835.14 EMC87716.1 - 2.6e-22 78.9 1.1 1.6e-17 63.5 0.0 5.1 6 0 0 6 6 6 1 MG2 domain ANATO PF01821.13 EMC87716.1 - 2.1e-14 53.3 8.7 2.1e-14 53.3 6.0 1.8 2 0 0 2 2 2 1 Anaphylotoxin-like domain Thiol-ester_cl PF10569.4 EMC87716.1 - 2.5e-14 52.1 0.0 5.2e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 EMC87716.1 - 6.1e-11 42.7 1.3 3e-06 27.6 0.0 2.9 1 1 2 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMC87716.1 - 4e-06 26.8 0.0 0.00025 20.9 0.0 2.8 1 1 1 2 2 2 1 Prenyltransferase-like Ufm1 PF03671.9 EMC87717.1 - 4e-51 170.6 0.3 4.5e-51 170.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein RA PF00788.18 EMC87717.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Ion_trans PF00520.26 EMC87718.1 - 2.2e-34 118.4 14.5 3.6e-34 117.7 10.0 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.6 EMC87718.1 - 1.9e-30 104.5 1.7 5.9e-30 102.9 1.2 2.0 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 EMC87718.1 - 7.6e-13 48.6 0.8 2.8e-07 30.7 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC87718.1 - 4.8e-11 42.8 0.1 0.00011 22.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC87718.1 - 3.7e-09 35.9 1.7 0.00052 19.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EMC87718.1 - 1e-06 28.3 3.3 0.054 13.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMC87718.1 - 1.1e-06 28.7 0.1 0.047 13.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.7 EMC87718.1 - 0.0021 16.5 16.9 0.033 12.6 11.7 2.4 1 1 0 1 1 1 1 Polycystin cation channel Fasciclin PF02469.17 EMC87719.1 - 4.5e-105 346.7 0.1 2.2e-27 95.6 0.3 4.4 4 0 0 4 4 4 4 Fasciclin domain Pkinase PF00069.20 EMC87720.1 - 2.4e-34 118.6 0.0 2.6e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87720.1 - 1.8e-28 99.3 0.0 2.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC87720.1 - 0.08 12.6 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family CoaE PF01121.15 EMC87720.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase Kdo PF06293.9 EMC87720.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EMC87721.1 - 1.1e-43 149.3 0.0 1.1e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87721.1 - 4.8e-34 117.6 0.0 5.2e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Fringe PF02434.11 EMC87723.1 - 8.2e-15 54.7 0.7 3.8e-14 52.5 0.5 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EMC87723.1 - 1.4e-09 37.8 0.5 3.3e-05 23.5 0.2 2.2 1 1 1 2 2 2 2 Galactosyltransferase Asn_synthase PF00733.16 EMC87724.1 - 1.7e-60 204.6 0.0 2.3e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMC87724.1 - 6.6e-26 90.4 0.0 1.2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMC87724.1 - 4.4e-21 75.2 0.0 1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMC87724.1 - 8.3e-09 34.6 0.0 0.00012 20.8 0.0 2.4 1 1 0 2 2 2 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 EMC87724.1 - 8.4e-08 31.6 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein Tachykinin PF02202.11 EMC87725.1 - 2e-10 39.2 1.1 0.0007 19.0 0.6 2.4 2 0 0 2 2 2 2 Tachykinin family Bombesin PF02044.12 EMC87725.1 - 1.4 8.5 5.1 4.7 6.7 0.4 2.5 2 0 0 2 2 2 0 Bombesin-like peptide CEP19 PF14933.1 EMC87726.1 - 0.051 13.8 1.0 0.054 13.7 0.7 1.1 1 0 0 1 1 1 0 CEP19-like protein Tup_N PF08581.5 EMC87726.1 - 0.073 13.2 2.3 0.088 13.0 1.6 1.2 1 0 0 1 1 1 0 Tup N-terminal DLL_N PF12413.3 EMC87727.1 - 1.4e-25 90.1 22.2 1.4e-25 90.1 15.4 2.1 2 0 0 2 2 2 1 Homeobox protein distal-less-like N terminal Homeobox PF00046.24 EMC87727.1 - 2.1e-20 72.0 2.4 3.2e-20 71.4 1.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC87727.1 - 0.036 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain DSS1_SEM1 PF05160.8 EMC87728.1 - 1.8e-12 46.8 10.6 2.1e-12 46.6 7.3 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Mito_carr PF00153.22 EMC87729.1 - 7.2e-74 243.6 0.8 4.1e-27 93.7 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EMC87729.1 - 3.6e-09 35.2 1.1 0.047 13.0 0.1 5.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 EMC87729.1 - 1.8e-08 33.5 0.8 0.0048 16.6 0.0 5.5 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EMC87729.1 - 3.2e-07 30.3 1.0 0.05 13.7 0.0 4.7 3 1 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC87729.1 - 1.9e-06 27.4 1.5 0.15 11.6 0.0 4.3 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC87729.1 - 3.5e-05 22.9 0.3 1.1 8.7 0.0 3.8 3 0 0 3 3 3 2 EF hand Dynein_IC2 PF11540.3 EMC87730.1 - 1.1e-17 63.0 0.0 2.3e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.27 EMC87730.1 - 2.5e-14 52.5 14.6 5.1e-06 26.1 0.2 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat BCDHK_Adom3 PF10436.4 EMC87731.1 - 6.1e-50 168.9 0.0 8.5e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMC87731.1 - 8.7e-20 70.5 0.0 1.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC87731.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.2 EMC87732.1 - 4e-68 225.8 34.4 1.5e-17 63.7 0.6 4.5 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EMC87732.1 - 1e-30 103.9 13.7 0.00017 21.2 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EMC87732.1 - 2.6e-24 85.1 7.8 6.5e-08 32.8 0.2 6.8 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC87732.1 - 8.7e-20 70.3 11.7 5.6e-05 23.2 0.1 5.1 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC87732.1 - 1.6e-15 55.6 17.3 0.03 14.5 0.3 8.3 9 1 0 9 9 9 4 Ankyrin repeat SOCS_box PF07525.11 EMC87732.1 - 3.3e-13 49.2 5.1 7.8e-13 48.0 3.5 1.7 1 0 0 1 1 1 1 SOCS box Arylesterase PF01731.15 EMC87733.1 - 2.9e-41 139.3 1.4 5e-41 138.5 0.9 1.4 1 0 0 1 1 1 1 Arylesterase SGL PF08450.7 EMC87733.1 - 4.8e-09 35.9 0.0 6.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EMC87733.1 - 0.00021 21.2 0.0 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 Strictosidine synthase Glyco_hydro_42C PF08533.5 EMC87733.1 - 0.11 12.0 0.1 0.35 10.3 0.1 1.9 1 1 0 1 1 1 0 Beta-galactosidase C-terminal domain SAM_2 PF07647.12 EMC87734.1 - 2e-16 59.5 0.9 4.6e-16 58.4 0.6 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 EMC87734.1 - 3.4e-14 52.7 2.0 9.8e-14 51.3 1.4 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SAM_1 PF00536.25 EMC87734.1 - 1.2e-13 51.0 1.1 2.7e-13 49.8 0.8 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC87734.1 - 0.0083 15.8 0.1 0.027 14.2 0.1 1.8 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sarcoglycan_2 PF05510.8 EMC87735.1 - 2e-162 539.9 0.0 2.3e-162 539.7 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Cas1_AcylT PF07779.7 EMC87736.1 - 6.6e-226 750.4 29.0 8.6e-226 750.0 20.1 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EMC87736.1 - 8.4e-29 101.1 0.2 1.2e-28 100.6 0.2 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Collagen PF01391.13 EMC87737.1 - 7.5e-167 541.0 677.1 4.9e-10 38.7 23.7 20.9 2 1 13 15 15 15 12 Collagen triple helix repeat (20 copies) COLFI PF01410.13 EMC87737.1 - 4.3e-95 317.1 0.0 5.3e-95 316.8 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SNARE PF05739.14 EMC87739.1 - 5.8e-12 45.1 0.2 6.9e-12 44.8 0.1 1.1 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 EMC87739.1 - 0.00043 19.9 0.1 0.00056 19.5 0.1 1.2 1 0 0 1 1 1 1 Sec20 Use1 PF09753.4 EMC87739.1 - 0.013 14.9 0.0 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF4407 PF14362.1 EMC87739.1 - 0.032 13.2 0.0 0.037 12.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Polysacc_synt_4 PF04669.8 EMC87739.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis G-gamma PF00631.17 EMC87740.1 - 5.1e-15 54.9 3.0 5.9e-14 51.5 2.1 1.9 1 1 0 1 1 1 1 GGL domain DUF4391 PF14335.1 EMC87740.1 - 0.11 11.9 0.3 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) HALZ PF02183.13 EMC87740.1 - 0.21 11.3 1.9 0.36 10.5 1.3 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Kunitz_BPTI PF00014.18 EMC87741.1 - 5.9e-59 196.0 33.5 1.8e-22 79.2 2.8 3.1 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Prion PF00377.13 EMC87741.1 - 0.0017 18.0 0.1 0.0017 18.0 0.1 1.8 2 0 0 2 2 2 1 Prion/Doppel alpha-helical domain Toxin_2 PF00451.14 EMC87741.1 - 0.22 11.6 7.5 0.22 11.6 0.2 4.2 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Thionin PF00321.12 EMC87741.1 - 0.35 11.1 0.1 0.35 11.1 0.0 3.5 3 0 0 3 3 3 0 Plant thionin 7tm_2 PF00002.19 EMC87742.1 - 4.8e-78 261.6 17.4 6.1e-78 261.2 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC87742.1 - 3.3e-18 65.4 7.4 3.3e-18 65.4 5.1 1.9 2 0 0 2 2 2 1 Hormone receptor domain DUF2451 PF10474.4 EMC87743.1 - 9e-101 336.5 2.8 2.3e-100 335.2 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 EMC87743.1 - 4.6e-96 321.1 11.5 1.2e-95 319.7 8.0 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) I-set PF07679.11 EMC87744.1 - 1.3e-16 60.1 0.0 2.1e-08 33.9 0.0 4.3 4 1 0 4 4 4 3 Immunoglobulin I-set domain V-set PF07686.12 EMC87744.1 - 9.1e-14 51.3 0.1 0.00016 21.5 0.0 4.1 2 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC87744.1 - 1.8e-12 47.1 0.2 6.3e-07 29.4 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 EMC87744.1 - 2.7e-12 46.9 4.1 5.9e-09 36.3 0.8 3.5 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 EMC87744.1 - 3.8e-09 36.5 0.1 4.8e-05 23.3 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC87744.1 - 0.02 14.8 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain SAM_1 PF00536.25 EMC87745.1 - 5.7e-05 23.2 0.1 0.00033 20.7 0.0 2.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC87745.1 - 0.0084 15.8 0.1 0.05 13.3 0.1 2.2 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Pkinase PF00069.20 EMC87746.1 - 1.4e-69 234.1 0.0 1.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87746.1 - 3.1e-36 124.7 0.0 6.7e-36 123.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMC87746.1 - 3.4e-07 30.2 0.1 0.0016 18.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC87746.1 - 9e-05 21.6 0.0 0.0002 20.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC87746.1 - 0.0006 18.8 0.0 0.0013 17.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EMC87746.1 - 0.035 13.4 0.0 0.088 12.1 0.0 1.7 1 1 0 1 1 1 0 RIO1 family RRM_5 PF13893.1 EMC87748.1 - 2.6e-07 30.4 0.1 4.5e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC87748.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Sipho_Gp37 PF14594.1 EMC87749.1 - 0.09 11.9 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein IBR PF01485.16 EMC87750.1 - 1.9e-22 78.8 36.4 1.4e-13 50.4 0.9 5.0 4 1 1 5 5 5 2 IBR domain Ank_2 PF12796.2 EMC87750.1 - 6.4e-16 58.4 0.4 3e-10 40.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC87750.1 - 1.3e-12 47.4 0.9 5.2e-08 32.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC87750.1 - 5.9e-12 44.7 0.0 1.7e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMC87750.1 - 1e-07 32.2 0.6 0.0068 16.9 0.0 3.6 4 1 1 5 5 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC87750.1 - 8.5e-07 28.6 1.7 0.005 16.9 0.0 3.4 3 0 0 3 3 2 2 Ankyrin repeat zf-RING_2 PF13639.1 EMC87750.1 - 2.5e-05 23.9 31.5 5.7e-05 22.8 3.8 3.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 EMC87750.1 - 0.0027 17.5 6.5 0.0027 17.5 4.5 4.2 3 1 1 4 4 4 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMC87750.1 - 0.0046 16.5 6.1 0.0046 16.5 4.2 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC87750.1 - 0.0081 16.1 8.9 0.0081 16.1 6.2 4.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) UIM PF02809.15 EMC87750.1 - 0.017 14.6 1.8 0.036 13.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-RING_UBOX PF13445.1 EMC87750.1 - 3.3 7.5 21.0 0.021 14.5 2.8 4.4 4 0 0 4 4 4 0 RING-type zinc-finger FERM_M PF00373.13 EMC87751.1 - 2.4e-20 72.9 0.1 6.5e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 FERM central domain Ank_5 PF13857.1 EMC87751.1 - 9.2e-18 63.8 0.5 1.3e-10 41.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC87751.1 - 5e-16 58.8 0.0 1.6e-08 34.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC87751.1 - 1.9e-13 50.5 0.5 5.3e-07 29.9 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC87751.1 - 2.9e-12 45.7 0.2 0.0026 17.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMC87751.1 - 7.1e-10 38.1 0.1 0.011 15.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.17 EMC87752.1 - 1.2e-74 251.4 0.0 1.5e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Frizzled PF01534.12 EMC87754.1 - 2.8e-114 381.3 9.8 3.1e-114 381.1 6.8 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 EMC87754.1 - 0.00036 19.5 3.9 0.00036 19.5 2.7 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7TM_GPCR_Srw PF10324.4 EMC87754.1 - 0.014 14.5 0.8 0.02 14.0 0.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw zf-DHHC PF01529.15 EMC87754.1 - 0.034 13.5 1.3 0.88 8.9 0.0 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase Pkinase PF00069.20 EMC87755.1 - 5.5e-66 222.3 0.0 7.3e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87755.1 - 1.5e-32 112.7 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87755.1 - 0.0007 18.6 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC87755.1 - 0.0021 17.8 0.0 0.092 12.4 0.0 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family Shisa PF13908.1 EMC87756.1 - 0.00025 21.2 0.6 0.00027 21.1 0.4 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 EMC87756.1 - 0.001 18.6 3.7 0.0023 17.5 2.6 1.5 1 1 0 1 1 1 1 IncA protein FAM163 PF15069.1 EMC87756.1 - 0.0021 18.6 0.3 0.004 17.7 0.2 1.5 1 0 0 1 1 1 1 FAM163 family EphA2_TM PF14575.1 EMC87756.1 - 0.0026 18.1 0.2 0.0045 17.3 0.1 1.5 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 EMC87756.1 - 0.004 16.8 2.1 0.004 16.8 1.4 1.6 1 1 0 1 1 1 1 CD34/Podocalyxin family Corona_S2 PF01601.11 EMC87756.1 - 0.0046 15.1 1.6 0.007 14.5 1.1 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein UPF0560 PF10577.4 EMC87756.1 - 0.0051 15.1 0.4 0.0051 15.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 TMEM154 PF15102.1 EMC87756.1 - 0.0087 15.7 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF3609 PF12259.3 EMC87756.1 - 0.014 14.0 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF3481 PF11980.3 EMC87756.1 - 0.029 14.2 0.2 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) LST1 PF05083.8 EMC87756.1 - 0.03 14.3 2.2 0.059 13.3 1.5 1.4 1 0 0 1 1 1 0 LST-1 protein DUF4094 PF13334.1 EMC87756.1 - 0.031 14.6 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) MAS20 PF02064.10 EMC87756.1 - 0.034 14.0 0.7 0.047 13.6 0.5 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor DUF4500 PF14937.1 EMC87756.1 - 0.04 13.7 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Protocadherin PF08374.6 EMC87756.1 - 0.069 12.7 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF1191 PF06697.7 EMC87756.1 - 0.074 11.8 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CCER1 PF15482.1 EMC87756.1 - 0.14 11.7 3.7 0.17 11.4 2.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Prominin PF05478.6 EMC87756.1 - 1.7 6.0 5.7 2.1 5.7 4.0 1.1 1 0 0 1 1 1 0 Prominin Synaphin PF05835.7 EMC87756.1 - 1.8 8.6 7.9 2.3 8.3 5.5 1.1 1 0 0 1 1 1 0 Synaphin protein Claudin_2 PF13903.1 EMC87757.1 - 9.1e-08 31.9 9.6 1.6e-07 31.1 6.7 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MMR_HSR1 PF01926.18 EMC87758.1 - 1.6e-21 76.4 0.0 2.8e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 EMC87758.1 - 5.5e-18 65.1 3.0 4.3e-17 62.1 2.0 2.2 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.13 EMC87758.1 - 9e-12 44.5 0.1 5.2e-11 42.0 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMC87758.1 - 4.3e-06 26.2 0.1 0.00074 18.9 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMC87758.1 - 0.00031 19.6 0.1 0.34 9.6 0.0 2.2 2 0 0 2 2 2 2 ArgK protein ATP_bind_1 PF03029.12 EMC87758.1 - 0.0042 16.6 0.3 0.025 14.1 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EMC87758.1 - 0.015 15.8 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EMC87758.1 - 0.097 12.4 3.0 3.5 7.4 0.0 2.6 2 2 1 3 3 3 0 Dynamin family cobW PF02492.14 EMC87758.1 - 0.11 11.8 0.1 5 6.5 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ferric_reduct PF01794.14 EMC87761.1 - 1.9e-19 69.9 5.0 1.9e-19 69.9 3.4 2.6 2 1 1 3 3 3 2 Ferric reductase like transmembrane component F420_oxidored PF03807.12 EMC87761.1 - 1.4e-17 63.9 0.0 2.5e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMC87761.1 - 5.4e-06 26.3 0.0 9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EMC87761.1 - 0.00095 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMC87761.1 - 0.0061 16.5 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF202 PF02656.10 EMC87761.1 - 0.01 16.0 4.6 0.34 11.1 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF202) IlvN PF07991.7 EMC87761.1 - 0.058 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EMC87761.1 - 0.16 12.2 0.1 0.56 10.4 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF2768 PF10966.3 EMC87761.1 - 0.88 9.7 7.0 0.17 12.0 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Ferric_reduct PF01794.14 EMC87762.1 - 3.9e-17 62.5 14.1 1e-16 61.1 5.0 2.5 2 1 1 3 3 3 2 Ferric reductase like transmembrane component DUF3671 PF12420.3 EMC87762.1 - 0.82 9.6 8.8 0.52 10.3 0.8 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF999 PF06198.6 EMC87762.1 - 0.83 9.4 5.6 0.65 9.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF999) Ferric_reduct PF01794.14 EMC87763.1 - 2.2e-24 85.9 4.7 2.2e-24 85.9 3.3 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component F420_oxidored PF03807.12 EMC87763.1 - 5.2e-13 49.2 0.0 9e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EMC87763.1 - 8.7e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EMC87763.1 - 0.00075 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EMC87763.1 - 0.0018 17.4 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMC87763.1 - 0.0048 16.9 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Rossmann-like PF10727.4 EMC87763.1 - 0.049 13.3 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 EMC87763.1 - 0.067 12.9 0.1 0.63 9.7 0.0 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EF-hand_1 PF00036.27 EMC87764.1 - 5.5e-18 62.8 0.3 0.00018 20.5 0.0 5.3 5 1 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EMC87764.1 - 3.9e-16 58.3 0.1 1.3e-12 47.0 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 EMC87764.1 - 1.6e-13 50.5 0.2 2.9e-06 27.3 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC87764.1 - 1.9e-13 49.0 0.5 0.00089 18.9 0.0 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EMC87764.1 - 9.5e-13 46.8 0.2 0.00072 18.7 0.0 4.0 4 0 0 4 4 4 3 EF hand Reprolysin PF01421.14 EMC87765.1 - 2.9e-55 186.9 0.0 6.3e-55 185.8 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC87765.1 - 6.4e-30 103.6 7.0 6.4e-30 103.6 4.9 3.8 3 2 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.18 EMC87765.1 - 3.1e-18 65.7 29.6 3.1e-18 65.7 20.5 3.5 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 EMC87765.1 - 2.4e-17 62.9 0.8 4.4e-17 62.1 0.6 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.1 EMC87765.1 - 4.2e-09 36.9 0.0 8.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMC87765.1 - 1.2e-06 28.5 0.0 4e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMC87765.1 - 0.00012 21.7 0.1 0.0004 19.9 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC87765.1 - 0.00037 20.6 0.1 0.0051 16.8 0.1 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 EMC87765.1 - 0.0039 17.3 11.4 0.0039 17.3 7.9 6.5 4 2 1 5 5 5 1 EGF-like domain zf-DBF PF07535.7 EMC87766.1 - 7.5e-17 60.7 2.0 2.7e-16 58.9 1.3 2.0 2 0 0 2 2 2 1 DBF zinc finger BRCT PF00533.21 EMC87766.1 - 0.00042 20.4 0.3 0.002 18.2 0.2 2.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DnaI_N PF07319.6 EMC87766.1 - 0.023 14.9 1.3 0.3 11.3 0.1 3.1 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Mito_carr PF00153.22 EMC87767.1 - 1.5e-67 223.3 0.1 2e-22 78.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RUN PF02759.14 EMC87768.1 - 5.6e-29 100.5 0.1 1.5e-28 99.2 0.0 1.7 2 0 0 2 2 2 1 RUN domain DUF4477 PF14780.1 EMC87768.1 - 0.044 13.1 0.4 0.31 10.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Drf_FH3 PF06367.11 EMC87768.1 - 0.064 12.6 5.6 0.14 11.5 3.8 1.6 1 0 0 1 1 1 0 Diaphanous FH3 Domain ABC_membrane PF00664.18 EMC87769.1 - 4.2e-153 508.5 36.8 1.1e-89 300.5 9.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC87769.1 - 1.9e-75 251.6 0.3 3.4e-37 127.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC87769.1 - 1.4e-16 60.4 1.8 7.3e-08 31.9 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EMC87769.1 - 3.7e-11 42.2 1.2 1.3e-05 24.0 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 EMC87769.1 - 7.6e-11 42.4 0.0 0.18 11.7 0.0 4.6 3 1 0 3 3 3 3 AAA domain AAA_22 PF13401.1 EMC87769.1 - 5e-07 29.9 3.5 0.026 14.6 0.2 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMC87769.1 - 6.3e-07 29.5 4.7 0.012 15.5 0.7 3.3 2 2 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EMC87769.1 - 6.3e-07 28.7 0.0 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EMC87769.1 - 2.2e-06 27.4 2.4 0.05 13.5 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EMC87769.1 - 3.2e-06 26.5 0.8 0.067 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMC87769.1 - 3.8e-06 27.7 0.0 0.094 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EMC87769.1 - 1.4e-05 25.2 4.0 0.36 11.0 0.6 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC87769.1 - 1.5e-05 24.7 0.7 0.45 10.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMC87769.1 - 1.6e-05 24.1 0.2 0.0087 15.1 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.15 EMC87769.1 - 6.3e-05 21.8 0.0 0.13 10.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_14 PF13173.1 EMC87769.1 - 0.0001 22.2 0.2 0.21 11.4 0.0 3.9 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 EMC87769.1 - 0.00012 22.0 3.3 0.075 12.8 0.2 3.6 3 1 0 3 3 3 2 Domain of unknown function DUF87 Rad17 PF03215.10 EMC87769.1 - 0.00026 19.8 0.9 0.3 9.7 0.0 2.8 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EMC87769.1 - 0.00061 19.7 3.0 0.8 9.6 0.4 3.4 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.1 EMC87769.1 - 0.00092 19.5 0.1 1.3 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EMC87769.1 - 0.00094 18.6 1.6 1.1 8.6 0.0 3.2 3 1 0 3 3 2 2 AAA domain PRK PF00485.13 EMC87769.1 - 0.0015 18.0 0.2 1.3 8.5 0.0 2.6 2 1 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.20 EMC87769.1 - 0.0024 17.4 3.2 3 7.2 0.4 3.5 2 1 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EMC87769.1 - 0.0028 17.3 0.9 0.83 9.4 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_10 PF12846.2 EMC87769.1 - 0.0028 17.1 1.1 9.2 5.5 0.0 4.2 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 EMC87769.1 - 0.0041 17.2 0.0 5.8 7.1 0.0 3.1 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 EMC87769.1 - 0.0043 17.5 0.1 3.4 8.1 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein DUF815 PF05673.8 EMC87769.1 - 0.0054 15.6 0.0 0.88 8.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EMC87769.1 - 0.011 14.9 0.0 0.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI tRNA_lig_kinase PF08303.6 EMC87769.1 - 0.012 15.5 0.0 6.3 6.6 0.0 2.8 2 0 0 2 2 2 0 tRNA ligase kinase domain APS_kinase PF01583.15 EMC87769.1 - 0.021 14.4 0.2 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.1 EMC87769.1 - 0.023 14.5 0.5 6 6.7 0.2 2.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EMC87769.1 - 0.024 14.2 0.3 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Carn_acyltransf PF00755.15 EMC87770.1 - 7.9e-188 625.2 0.0 9e-188 625.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Thioesterase PF00975.15 EMC87771.1 - 9e-41 140.5 0.0 1.1e-40 140.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EMC87771.1 - 1.5e-07 31.5 0.0 2.7e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC87771.1 - 5.1e-05 23.0 0.0 7.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC87771.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EMC87771.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 EMC87771.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ACBP PF00887.14 EMC87772.1 - 3.4e-31 106.7 0.1 3.7e-31 106.6 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 EMC87772.1 - 0.097 12.8 0.1 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 FERM central domain Ribosomal_L7Ae PF01248.21 EMC87773.1 - 3.1e-08 33.0 0.0 6.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMC87773.1 - 8.1e-06 25.7 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 NMT_C PF02799.10 EMC87775.1 - 8.5e-83 276.4 0.2 2.8e-82 274.7 0.1 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EMC87775.1 - 1.2e-81 272.1 0.0 1.9e-81 271.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_7 PF13508.1 EMC87775.1 - 0.0098 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC87775.1 - 0.014 15.2 0.0 0.069 13.0 0.0 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC87775.1 - 0.039 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NST1 PF13945.1 EMC87775.1 - 0.14 12.2 5.4 0.23 11.4 3.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator UPF0560 PF10577.4 EMC87776.1 - 0 1264.9 4.2 0 1264.8 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 MG1 PF11974.3 EMC87776.1 - 0.051 14.1 0.1 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 Alpha-2-macroglobulin MG1 domain Alpha_E2_glycop PF00943.14 EMC87776.1 - 0.082 11.5 0.3 0.14 10.7 0.2 1.3 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Orthoreo_P10 PF07204.6 EMC87776.1 - 0.092 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 IncA PF04156.9 EMC87776.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 IncA protein Adeno_E3_CR2 PF02439.10 EMC87776.1 - 0.2 11.2 1.5 0.36 10.3 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Integrin_alpha2 PF08441.7 EMC87777.1 - 1.4e-101 340.6 1.0 1.7e-101 340.3 0.7 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 EMC87777.1 - 1.3e-20 72.4 15.2 3.1e-08 33.0 0.0 5.2 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.1 EMC87777.1 - 3.3e-09 36.9 8.7 4e-07 30.3 1.0 4.2 1 1 4 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 EMC87777.1 - 0.00014 21.3 0.2 0.00014 21.3 0.2 2.0 2 0 0 2 2 2 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.1 EMC87777.1 - 0.012 15.6 3.5 0.62 10.1 0.0 4.6 5 0 0 5 5 5 0 FG-GAP repeat DUF4205 PF13898.1 EMC87778.1 - 3.9e-57 193.5 0.1 2.7e-51 174.3 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) CheR PF01739.13 EMC87778.1 - 0.026 13.8 0.1 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PTE PF02126.13 EMC87779.1 - 3.8e-120 400.5 0.0 4.4e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.16 EMC87779.1 - 4.4e-07 29.3 0.0 6.9e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase C1q PF00386.16 EMC87780.1 - 6.5e-18 64.9 0.0 7.1e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 EMC87780.1 - 0.039 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family LRR_4 PF12799.2 EMC87781.1 - 5.5e-28 96.0 25.3 1.5e-08 34.0 1.9 5.6 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC87781.1 - 5.6e-22 77.2 17.6 5.9e-09 35.5 2.7 4.0 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EMC87781.1 - 3.8e-20 68.7 21.6 0.0097 15.8 0.1 7.4 7 0 0 7 7 7 7 Leucine Rich Repeat LRR_7 PF13504.1 EMC87781.1 - 1.7e-12 45.3 20.4 1.2 9.6 0.0 7.8 8 0 0 8 8 8 7 Leucine rich repeat LRR_6 PF13516.1 EMC87781.1 - 4.7e-07 29.2 22.7 3.5 7.9 0.3 7.4 7 0 0 7 7 7 5 Leucine Rich repeat CUB PF00431.15 EMC87782.1 - 0 2352.4 16.7 1.3e-33 115.3 0.0 27.0 27 0 0 27 27 27 27 CUB domain CUB_2 PF02408.15 EMC87782.1 - 3.3e-21 75.0 43.2 0.0075 15.8 0.1 19.6 21 0 0 21 21 21 8 CUB-like domain RIO1 PF01163.17 EMC87782.1 - 2.8 7.2 0.0 9.7 5.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family PaRep2b PF07775.6 EMC87782.1 - 4.5 5.3 0.0 6.8 4.7 0.0 1.1 1 0 0 1 1 1 0 PaRep2b protein zf-H2C2_2 PF13465.1 EMC87785.1 - 1.2e-35 120.0 61.8 1.3e-08 34.6 3.7 8.7 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87785.1 - 2.4e-24 84.1 78.7 0.00033 20.7 3.4 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87785.1 - 9.6e-16 56.8 63.1 0.00022 21.3 0.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC87785.1 - 2.6e-11 43.2 54.8 0.0016 18.4 0.9 8.6 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC87785.1 - 6e-08 32.6 54.3 0.016 15.4 0.3 8.5 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC87785.1 - 7.1e-08 32.4 2.0 7.1e-08 32.4 1.4 4.5 4 1 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding Homeobox PF00046.24 EMC87785.1 - 4.5e-05 22.9 0.0 0.00032 20.2 0.0 2.5 2 0 0 2 2 2 1 Homeobox domain zf-C2H2_6 PF13912.1 EMC87785.1 - 0.0046 16.8 61.7 0.0084 15.9 0.6 8.5 8 0 0 8 8 8 3 C2H2-type zinc finger zf-C3HC4_4 PF15227.1 EMC87786.1 - 5.7e-16 58.1 8.7 5.7e-16 58.1 6.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMC87786.1 - 3.1e-12 45.9 6.9 3.1e-12 45.9 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 EMC87786.1 - 4.4e-10 39.2 0.7 4.4e-10 39.2 0.5 3.6 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_2 PF13923.1 EMC87786.1 - 4.5e-09 36.1 8.3 4.5e-09 36.1 5.7 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC87786.1 - 4.2e-08 32.7 5.0 4.2e-08 32.7 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC87786.1 - 5.4e-08 32.4 1.4 5.4e-08 32.4 1.0 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMC87786.1 - 8.9e-07 28.6 7.2 8.9e-07 28.6 5.0 2.2 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EMC87786.1 - 9e-07 28.5 6.9 9e-07 28.5 4.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EMC87786.1 - 0.00044 19.9 1.6 0.001 18.8 1.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EMC87786.1 - 0.0026 17.3 7.6 0.0026 17.3 5.2 3.0 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EMC87786.1 - 0.0026 17.5 1.7 0.0026 17.5 1.2 1.5 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) U-box PF04564.10 EMC87786.1 - 0.01 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 U-box domain zf-UDP PF14569.1 EMC87786.1 - 0.017 14.8 2.0 0.017 14.8 1.4 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-Nse PF11789.3 EMC87786.1 - 0.03 13.8 3.7 0.067 12.7 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EMC87786.1 - 0.17 11.7 8.3 0.04 13.7 2.4 2.3 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMC87786.1 - 0.71 10.0 10.8 0.73 9.9 4.4 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger IBR PF01485.16 EMC87786.1 - 0.79 9.6 15.4 0.36 10.7 0.8 3.2 1 1 1 2 2 2 0 IBR domain DZR PF12773.2 EMC87786.1 - 5.4 6.9 14.4 20 5.1 5.5 3.0 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EMC87786.1 - 6.7 6.5 10.0 9.9 5.9 4.0 2.9 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ARGLU PF15346.1 EMC87789.1 - 0.21 11.3 16.0 0.25 11.1 11.1 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 TRAP_alpha PF03896.11 EMC87789.1 - 0.31 9.9 7.1 0.38 9.7 4.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Afi1 PF07792.7 EMC87789.1 - 0.32 10.9 5.5 0.37 10.7 3.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TFIIF_alpha PF05793.7 EMC87789.1 - 0.58 8.4 20.2 0.63 8.3 14.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EMC87789.1 - 2.3 6.1 12.9 2.6 5.9 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 EMC87789.1 - 2.4 7.9 8.2 3.6 7.3 5.7 1.3 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 EMC87789.1 - 3 7.1 9.2 3.5 6.9 6.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Nop14 PF04147.7 EMC87789.1 - 3.3 5.5 16.3 3.6 5.3 11.3 1.0 1 0 0 1 1 1 0 Nop14-like family XAP5 PF04921.9 EMC87789.1 - 4.1 6.9 10.3 5.6 6.4 7.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3807 PF12720.2 EMC87789.1 - 5.6 7.0 14.7 6.8 6.8 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.7 EMC87789.1 - 7.2 6.4 14.7 9 6.0 10.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.8 EMC87789.1 - 7.7 5.6 16.1 8.7 5.4 11.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4604 PF15377.1 EMC87789.1 - 9.6 6.3 21.5 10 6.2 14.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) TraB PF01963.12 EMC87790.1 - 4.9e-08 32.7 0.0 3.9e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 TraB family Ras PF00071.17 EMC87791.1 - 7.9e-18 64.3 0.0 8.3e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 EMC87791.1 - 0.0062 15.8 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B TPP_enzyme_M PF00205.17 EMC87791.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain GTP_EFTU PF00009.22 EMC87791.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HEAT_2 PF13646.1 EMC87792.1 - 5e-22 77.9 0.7 8.6e-12 45.1 0.0 6.6 4 1 2 6 6 6 2 HEAT repeats HEAT PF02985.17 EMC87792.1 - 1.7e-19 68.0 10.4 1.9e-05 24.3 0.0 9.1 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EMC87792.1 - 2.2e-19 69.3 1.2 5.4e-07 29.9 0.0 8.0 8 0 0 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMC87792.1 - 3.4e-12 46.5 6.9 1.9e-05 24.9 0.0 8.2 6 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EMC87792.1 - 2.7e-05 23.8 0.8 3.6 7.5 0.0 5.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EMC87792.1 - 2.9e-05 23.9 0.1 0.0011 18.8 0.0 3.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain PTP_N PF12453.3 EMC87793.1 - 0.58 9.8 3.8 4 7.1 0.2 2.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal RhoGEF PF00621.15 EMC87794.1 - 5.1e-31 107.9 1.2 5.1e-31 107.9 0.8 1.8 2 0 0 2 2 2 1 RhoGEF domain FERM_C PF09380.5 EMC87794.1 - 2.4e-25 88.5 0.4 5.7e-25 87.3 0.3 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.24 EMC87794.1 - 5.7e-25 87.5 0.5 1.7e-15 57.1 0.6 2.7 2 0 0 2 2 2 2 PH domain FA PF08736.6 EMC87794.1 - 6.5e-16 57.8 3.6 1.2e-15 56.9 1.7 2.2 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.5 EMC87794.1 - 7.4e-14 51.5 0.1 2.7e-13 49.7 0.0 2.1 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 EMC87794.1 - 1.7e-11 44.3 0.8 1.7e-11 44.3 0.5 2.4 2 1 0 2 2 2 1 FERM central domain Pkinase PF00069.20 EMC87795.1 - 1e-53 182.1 0.0 1.4e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87795.1 - 5.7e-39 133.7 0.0 7.6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.6 EMC87795.1 - 9.7e-05 21.6 0.0 0.00022 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.1 EMC87795.1 - 0.00076 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC87795.1 - 0.082 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTR2 PF00854.16 EMC87796.1 - 3.5e-123 411.0 11.3 3e-121 404.7 4.9 2.1 2 0 0 2 2 2 2 POT family AlgF PF11182.3 EMC87796.1 - 0.002 17.8 0.0 0.024 14.3 0.0 2.4 3 0 0 3 3 3 1 Alginate O-acetyl transferase AlgF Ded_cyto PF06920.8 EMC87797.1 - 2.2e-65 219.2 1.2 2.2e-65 219.2 0.8 2.7 3 0 0 3 3 3 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EMC87797.1 - 1.3e-58 197.6 0.2 5e-58 195.7 0.1 2.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 EMC87797.1 - 5.4e-31 106.3 0.2 1.6e-30 104.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.24 EMC87797.1 - 1.3e-12 47.8 0.2 7.4e-12 45.3 0.1 2.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EMC87797.1 - 2.8e-05 24.2 0.0 0.00016 21.8 0.0 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMC87797.1 - 0.023 14.7 0.1 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain UBA PF00627.26 EMC87798.1 - 7e-13 47.9 0.4 1.3e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain FeoA PF04023.9 EMC87798.1 - 0.046 13.6 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 FeoA domain TetR_C PF02909.12 EMC87798.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain 7tm_1 PF00001.16 EMC87799.1 - 5.5e-52 176.4 13.7 7.2e-52 176.0 9.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC87799.1 - 0.00017 21.4 2.2 0.00017 21.4 1.5 3.1 2 1 1 3 3 3 1 Olfactory receptor TAS2R PF05296.8 EMC87799.1 - 0.12 11.2 9.0 0.17 10.7 1.6 2.2 2 0 0 2 2 2 0 Mammalian taste receptor protein (TAS2R) DUF3357 PF11837.3 EMC87799.1 - 0.31 10.9 2.0 0.37 10.6 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Na_Ca_ex PF01699.19 EMC87799.1 - 6.9 6.2 8.7 0.39 10.3 0.4 2.6 2 1 1 3 3 3 0 Sodium/calcium exchanger protein HpcH_HpaI PF03328.9 EMC87800.1 - 1.4e-46 158.1 0.0 1.8e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EMC87800.1 - 2.3e-10 39.8 0.2 4e-06 25.8 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold zf-C2H2 PF00096.21 EMC87801.1 - 3.3e-12 45.9 19.7 6e-06 26.2 2.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC87801.1 - 9.5e-11 41.4 27.2 7.7e-07 29.0 2.1 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC87801.1 - 6.4e-09 35.5 14.0 0.00044 20.4 0.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC87801.1 - 0.012 15.7 15.4 0.03 14.4 1.2 3.9 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC87801.1 - 0.027 14.6 15.2 0.067 13.4 0.8 4.0 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC87801.1 - 0.065 13.1 3.7 4 7.4 0.1 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.7 EMC87801.1 - 2.6 8.3 11.0 2.7 8.2 0.1 3.0 1 1 2 3 3 3 0 CHORD p450 PF00067.17 EMC87802.1 - 3.5e-17 62.0 0.1 3.7e-17 61.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.1 EMC87803.1 - 3e-09 36.5 10.2 5.4e-09 35.7 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC87803.1 - 3.2e-08 33.1 9.4 6e-08 32.2 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC87803.1 - 5.3e-06 26.3 11.4 1.1e-05 25.3 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC87803.1 - 2.3e-05 24.0 7.9 2.5e-05 23.9 3.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EMC87803.1 - 7.8e-05 22.2 10.3 0.00014 21.4 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC87803.1 - 8.3e-05 22.1 8.7 8.3e-05 22.1 6.0 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EMC87803.1 - 0.0069 16.2 4.7 0.0069 16.2 3.2 1.6 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 EMC87803.1 - 0.027 14.3 2.3 0.027 14.3 1.6 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger GAGA PF09237.6 EMC87803.1 - 0.038 13.5 4.8 0.52 9.9 0.2 2.5 1 1 1 2 2 2 0 GAGA factor zf-RING_4 PF14570.1 EMC87803.1 - 0.044 13.3 7.6 0.083 12.4 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMC87803.1 - 0.92 9.4 16.7 0.72 9.7 9.0 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EMC87803.1 - 1.3 9.1 5.5 3.7 7.7 3.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DUF4379 PF14311.1 EMC87803.1 - 1.5 8.7 4.1 12 5.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4379) zf-MIZ PF02891.15 EMC87803.1 - 5.8 6.5 11.7 25 4.4 8.1 2.2 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EMC87803.1 - 7.9 6.3 11.2 19 5.0 3.8 2.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein PIRT PF15099.1 EMC87804.1 - 2.6e-48 162.5 0.1 3e-48 162.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family 7TM_GPCR_Srz PF10325.4 EMC87804.1 - 0.00079 18.6 1.2 0.00091 18.4 0.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz SdpI PF13630.1 EMC87804.1 - 0.0015 18.1 4.0 0.06 13.0 3.3 2.1 1 1 1 2 2 2 2 SdpI/YhfL protein family L_HGMIC_fpl PF10242.4 EMC87804.1 - 0.0015 18.5 0.3 0.0017 18.3 0.2 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein TMEM171 PF15471.1 EMC87804.1 - 0.077 11.7 0.3 0.1 11.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF973 PF06157.6 EMC87804.1 - 0.088 11.7 0.4 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Neurensin PF14927.1 EMC87804.1 - 0.21 10.9 3.1 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 Neurensin Shisa PF13908.1 EMC87805.1 - 1.9e-17 64.0 0.6 2.4e-17 63.7 0.4 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3136 PF11334.3 EMC87805.1 - 0.03 13.7 0.7 0.056 12.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) PBP PF01161.15 EMC87808.1 - 4.1e-22 78.5 0.1 4.9e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MHC_II_alpha PF00993.15 EMC87809.1 - 3.5e-27 93.8 0.1 4.8e-27 93.3 0.1 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain C1-set PF07654.10 EMC87809.1 - 7.1e-26 90.0 0.0 1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC87809.1 - 8.8e-06 25.5 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain MHC_II_beta PF00969.14 EMC87810.1 - 1e-37 127.9 0.2 1.3e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain MHC_I PF00129.13 EMC87810.1 - 0.0079 15.5 0.1 0.0097 15.2 0.0 1.0 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 7tm_1 PF00001.16 EMC87811.1 - 1.9e-19 69.8 2.8 2.4e-19 69.5 2.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Se-cys_synth_N PF12390.3 EMC87812.1 - 3.8e-05 23.6 11.5 1.2 9.2 0.1 4.5 4 0 0 4 4 4 4 Selenocysteine synthase N terminal ART PF01129.13 EMC87813.1 - 4.1e-31 107.8 0.4 4.5e-31 107.6 0.3 1.0 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.9 EMC87813.1 - 0.0085 15.3 0.0 0.0099 15.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme zf-RING_2 PF13639.1 EMC87814.1 - 1.7e-10 40.5 5.7 2.9e-10 39.7 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC87814.1 - 5.9e-07 29.5 3.0 9.9e-07 28.7 2.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC87814.1 - 5.2e-05 22.8 5.6 9.3e-05 22.0 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC87814.1 - 0.00047 19.7 5.8 0.0011 18.5 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC87814.1 - 0.00051 19.6 6.1 0.0014 18.2 4.0 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC87814.1 - 0.0075 16.0 5.1 0.022 14.5 3.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.7 EMC87814.1 - 0.022 14.8 1.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.1 EMC87814.1 - 0.046 13.7 10.0 0.18 11.8 6.8 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC87814.1 - 0.047 13.4 2.5 0.086 12.5 1.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EMC87814.1 - 0.063 13.2 7.8 1.4 8.8 5.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Cys_rich_CPXG PF14255.1 EMC87814.1 - 0.07 12.9 1.9 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-UDP PF14569.1 EMC87814.1 - 0.23 11.2 1.9 0.44 10.3 1.3 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.2 EMC87814.1 - 0.24 11.2 2.7 0.72 9.7 1.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon XRCC1_N PF01834.11 EMC87815.1 - 0.00041 19.8 0.0 0.00042 19.8 0.0 1.0 1 0 0 1 1 1 1 XRCC1 N terminal domain Reo_sigmaC PF04582.7 EMC87816.1 - 0.0058 15.8 11.6 0.26 10.4 0.8 3.1 1 1 1 3 3 3 2 Reovirus sigma C capsid protein DUF3584 PF12128.3 EMC87816.1 - 0.015 12.6 43.3 0.02 12.2 30.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2580 PF10824.3 EMC87816.1 - 0.29 11.5 4.7 0.47 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) CENP-F_leu_zip PF10473.4 EMC87816.1 - 0.36 10.6 57.0 1.3 8.8 9.1 4.6 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.10 EMC87816.1 - 0.98 9.4 43.8 0.044 13.8 16.2 2.9 1 1 2 3 3 3 0 Fez1 ATG16 PF08614.6 EMC87816.1 - 1.9 8.3 46.5 2 8.2 6.4 3.8 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.6 EMC87816.1 - 6.6 6.0 25.7 2.7 7.3 2.3 3.8 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) LAMTOR PF15454.1 EMC87817.1 - 4.7e-18 65.2 0.4 7e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ANAPC15 PF15243.1 EMC87819.1 - 6e-44 148.0 14.8 6e-44 148.0 10.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 RNA_pol_3_Rpc31 PF11705.3 EMC87819.1 - 0.0033 17.3 19.4 0.0039 17.1 13.4 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 EMC87819.1 - 0.032 12.9 25.7 0.037 12.7 17.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CEP19 PF14933.1 EMC87819.1 - 0.066 13.5 6.7 0.083 13.1 4.6 1.1 1 0 0 1 1 1 0 CEP19-like protein BUD22 PF09073.5 EMC87819.1 - 0.43 9.5 14.8 0.48 9.4 10.3 1.0 1 0 0 1 1 1 0 BUD22 EBV-NA3 PF05009.7 EMC87819.1 - 2.2 7.4 9.7 2.5 7.2 6.8 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC27 PF09507.5 EMC87819.1 - 2.4 7.2 11.8 2.8 7.0 8.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.5 EMC87819.1 - 4.6 7.2 9.8 5.6 6.9 6.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EMC87819.1 - 5.7 4.8 19.7 6.6 4.6 13.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EMC87819.1 - 7.1 4.9 24.8 8.1 4.7 17.2 1.0 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EMC87819.1 - 9.8 5.3 16.8 13 4.9 11.6 1.3 1 0 0 1 1 1 0 NOA36 protein zf-H2C2_2 PF13465.1 EMC87820.1 - 3e-77 251.3 112.8 7.1e-09 35.5 2.5 14.4 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87820.1 - 3e-47 156.1 133.4 7.6e-06 25.9 1.6 13.9 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87820.1 - 4.1e-24 83.0 112.6 0.00089 19.4 0.2 13.7 14 1 0 14 14 14 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC87820.1 - 3.1e-12 46.2 61.8 0.043 13.9 0.1 12.5 12 1 1 13 13 13 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC87820.1 - 1.7e-07 30.9 92.2 0.012 15.5 0.2 13.6 14 0 0 14 14 14 7 C2H2-type zinc finger LIM PF00412.17 EMC87820.1 - 0.049 13.6 70.1 0.85 9.7 3.5 10.4 2 2 9 11 11 11 0 LIM domain BHD_1 PF10403.4 EMC87820.1 - 0.084 12.4 2.8 12 5.5 0.0 4.2 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 1 FYDLN_acid PF09538.5 EMC87820.1 - 0.16 12.5 25.3 99 3.5 1.0 9.4 3 3 5 8 8 8 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.17 EMC87820.1 - 7.1 6.4 61.6 1.3 8.8 1.8 8.4 4 4 3 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.1 EMC87822.1 - 6.2e-97 313.5 86.8 2.7e-09 36.8 0.2 14.3 14 0 0 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87822.1 - 1.3e-63 207.6 114.1 2.6e-06 27.4 1.7 13.7 13 1 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC87822.1 - 3.2e-39 130.4 97.6 0.0014 18.8 0.4 13.3 13 0 0 13 13 13 13 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC87822.1 - 1e-25 88.7 76.2 6e-05 22.7 0.1 13.4 13 0 0 13 13 13 9 C2H2-type zinc finger KRAB PF01352.22 EMC87822.1 - 8.2e-19 66.7 0.1 1.6e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 KRAB box zf-C2H2_jaz PF12171.3 EMC87822.1 - 6.4e-14 51.6 50.1 0.51 10.5 0.0 12.6 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC87822.1 - 5.2e-10 39.1 70.9 0.21 11.8 0.2 12.4 13 0 0 13 13 12 5 Zinc-finger of C2H2 type zf-LYAR PF08790.6 EMC87822.1 - 9.5e-07 28.4 66.2 0.11 12.2 0.8 11.6 12 0 0 12 12 12 6 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EMC87822.1 - 1.6e-06 27.6 52.4 0.59 9.8 0.1 11.6 13 0 0 13 13 13 4 Probable zinc-binding domain LIM PF00412.17 EMC87822.1 - 4e-05 23.5 63.3 1.4 9.0 1.5 11.3 2 1 11 13 13 12 8 LIM domain BolA PF01722.13 EMC87822.1 - 0.002 18.0 19.2 1 9.3 0.3 5.6 3 1 1 5 5 5 2 BolA-like protein YhfH PF14149.1 EMC87822.1 - 0.0028 17.4 27.8 11 5.9 0.2 9.1 9 0 0 9 9 9 0 YhfH-like protein BHD_1 PF10403.4 EMC87822.1 - 0.0054 16.2 0.5 22 4.6 0.0 4.4 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 1 FYDLN_acid PF09538.5 EMC87822.1 - 0.044 14.3 25.2 1.2 9.8 0.1 8.4 2 2 6 8 8 8 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.5 EMC87822.1 - 0.047 13.6 65.8 1.3 9.0 3.2 11.4 6 3 5 11 11 11 0 Zinc ribbon domain zf-AN1 PF01428.11 EMC87822.1 - 0.28 11.0 68.6 12 5.8 0.3 13.0 11 2 2 13 13 13 0 AN1-like Zinc finger zf-Di19 PF05605.7 EMC87822.1 - 0.43 10.7 68.1 0.65 10.1 0.5 8.9 4 2 3 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 EMC87822.1 - 0.78 9.4 52.4 0.56 9.9 1.0 8.1 1 1 10 11 11 11 0 Transcription elongation factor Elf1 like Siva PF05458.7 EMC87822.1 - 6.7 6.2 18.6 0.49 9.9 1.1 4.4 1 1 3 5 5 5 0 Cd27 binding protein (Siva) C1_4 PF07975.7 EMC87822.1 - 9.4 6.3 60.0 1.4 8.9 1.0 8.8 2 1 7 11 11 11 0 TFIIH C1-like domain CAF-1_p150 PF11600.3 EMC87823.1 - 0.0079 15.6 57.5 0.0096 15.3 39.8 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 EMC87823.1 - 0.61 9.7 14.5 0.76 9.3 10.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PLRV_ORF5 PF01690.12 EMC87823.1 - 1.1 8.3 15.4 1.3 8.1 10.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MIP-T3 PF10243.4 EMC87823.1 - 1.3 7.4 54.4 1.6 7.0 37.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CT47 PF15623.1 EMC87823.1 - 1.4 8.5 30.0 1.7 8.2 20.8 1.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 SprA-related PF12118.3 EMC87823.1 - 1.6 7.9 21.4 2.1 7.5 14.9 1.2 1 0 0 1 1 1 0 SprA-related family Hid1 PF12722.2 EMC87823.1 - 2.1 5.9 12.2 2.3 5.7 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF262 PF03235.9 EMC87823.1 - 2.4 8.0 9.1 2.6 7.9 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Hex_IIIa PF02455.11 EMC87823.1 - 6.7 5.2 11.3 7.7 5.0 7.8 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF1777 PF08648.7 EMC87823.1 - 9.4 5.9 46.6 15 5.3 32.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Asp-B-Hydro_N PF05279.6 EMC87823.1 - 9.6 5.9 25.9 12 5.6 17.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-H2C2_5 PF13909.1 EMC87824.1 - 3.8e-52 171.5 269.4 0.00015 21.8 0.6 32.4 32 0 0 32 32 32 26 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EMC87824.1 - 0.0003 20.8 0.7 0.0017 18.5 0.1 31.9 33 1 0 33 33 33 17 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC87824.1 - 0.0027 17.8 6.7 0.0027 17.8 4.7 29.9 34 0 0 34 34 34 11 Zinc-finger double domain zf-C2H2 PF00096.21 EMC87824.1 - 0.012 15.9 0.2 0.012 15.9 0.1 30.6 35 0 0 35 35 35 0 Zinc finger, C2H2 type DUF647 PF04884.9 EMC87826.1 - 8.2e-25 87.4 0.3 9.9e-25 87.1 0.2 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis 7tm_1 PF00001.16 EMC87827.1 - 2.5e-60 203.8 18.3 2.5e-60 203.8 12.7 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC87827.1 - 1.5e-05 24.3 25.4 0.0054 15.9 4.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx zf-LITAF-like PF10601.4 EMC87827.1 - 5.3 6.9 7.0 5.9 6.8 0.3 3.3 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain Serum_albumin PF00273.15 EMC87828.1 - 2.3e-74 248.6 14.9 3.1e-43 147.2 3.1 2.4 3 0 0 3 3 3 2 Serum albumin family VitD-bind_III PF09164.5 EMC87828.1 - 7.2e-16 57.5 19.6 1.6e-12 46.8 0.1 5.5 5 2 0 5 5 5 3 Vitamin D binding protein, domain III Mac PF12464.3 EMC87828.1 - 0.076 13.0 1.0 0.41 10.6 0.7 2.2 1 1 0 1 1 1 0 Maltose acetyltransferase dNK PF01712.14 EMC87830.1 - 1.6e-45 154.6 0.9 2.3e-45 154.0 0.6 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 EMC87830.1 - 3.7e-05 24.0 0.0 7.5e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMC87830.1 - 0.0011 18.3 0.1 0.0034 16.7 0.1 1.9 1 1 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EMC87830.1 - 0.0033 17.4 0.1 0.0055 16.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC87830.1 - 0.0049 16.7 0.0 0.056 13.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Mob1_phocein PF03637.12 EMC87831.1 - 4e-81 270.8 0.3 4.7e-81 270.6 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family RRM_6 PF14259.1 EMC87832.1 - 6.3e-37 125.3 0.1 4.9e-13 48.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC87832.1 - 6.3e-18 64.1 0.0 1.4e-07 31.0 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC87832.1 - 5.5e-05 22.9 0.1 3.5 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC87832.1 - 0.0028 17.4 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif PSCyt1 PF07635.6 EMC87832.1 - 0.071 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Planctomycete cytochrome C Nup35_RRM_2 PF14605.1 EMC87832.1 - 0.078 12.7 0.0 12 5.7 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DPRP PF04244.8 EMC87832.1 - 0.079 12.4 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein RUN PF02759.14 EMC87833.1 - 3.5e-33 114.1 0.9 4.6e-32 110.5 0.0 2.6 3 0 0 3 3 3 1 RUN domain Mod_r PF07200.8 EMC87833.1 - 0.01 15.7 1.4 0.01 15.7 1.0 3.8 4 1 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.7 EMC87833.1 - 0.014 15.2 2.8 0.014 15.2 2.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EMC87833.1 - 0.79 8.8 10.7 2.3 7.2 0.6 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 EMC87833.1 - 2.1 7.8 29.3 0.98 8.9 9.9 2.3 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Sas10 PF09368.5 EMC87834.1 - 7.8e-27 93.2 11.7 7.8e-27 93.2 8.1 2.0 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EMC87834.1 - 4.7e-16 58.7 0.2 4.7e-16 58.7 0.1 2.5 3 0 0 3 3 3 1 Sas10/Utp3/C1D family PRP1_N PF06424.7 EMC87834.1 - 7.3 6.9 13.7 1.1 9.5 2.9 2.5 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal Ig_J_chain PF15097.1 EMC87835.1 - 1.3e-68 228.7 7.6 1.5e-68 228.5 5.2 1.0 1 0 0 1 1 1 1 Immunoglobulin J chain PMG PF05287.7 EMC87835.1 - 0.28 10.9 4.8 0.14 11.9 1.7 1.6 2 0 0 2 2 2 0 PMG protein SDA1 PF05285.7 EMC87836.1 - 7.2e-67 225.9 50.1 2.1e-33 116.0 12.5 4.1 2 1 2 4 4 4 4 SDA1 NUC130_3NT PF08158.7 EMC87836.1 - 1.9e-24 85.6 1.1 1.9e-24 85.6 0.7 3.4 4 0 0 4 4 4 1 NUC130/3NT domain NAAA-beta PF15508.1 EMC87837.1 - 2.9e-10 40.3 0.0 6.3e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 EMC87837.1 - 7e-08 32.2 0.1 7.9e-05 22.2 0.0 2.3 2 1 0 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family Metallophos PF00149.23 EMC87838.1 - 1.5e-40 138.7 0.0 3.7e-40 137.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 EMC87838.1 - 4e-18 63.2 1.1 6.8e-06 25.0 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EMC87838.1 - 6.4e-16 58.2 9.2 8.6e-10 38.6 2.8 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC87838.1 - 4e-15 54.3 2.0 0.00068 18.8 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EMC87838.1 - 4.1e-15 55.1 1.8 4.9e-06 26.0 0.0 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC87838.1 - 1.3e-13 49.5 1.6 0.0035 17.0 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain PPP5 PF08321.7 EMC87838.1 - 4.2e-10 39.5 0.1 2e-08 34.1 0.0 3.2 2 1 1 3 3 3 1 PPP5 TPR repeat region IQ PF00612.22 EMC87838.1 - 0.00013 21.3 2.3 0.00037 19.8 1.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_4 PF12763.2 EMC87838.1 - 0.0018 17.9 4.3 0.3 10.8 0.2 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC87838.1 - 0.013 15.4 0.1 2.6 8.1 0.1 3.2 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Nup54 PF13874.1 EMC87839.1 - 5.2e-49 165.5 4.1 5.2e-49 165.5 2.8 2.1 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 FAST_2 PF08368.7 EMC87839.1 - 0.0097 16.2 0.5 0.064 13.6 0.0 2.5 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 Nucleoporin_FG PF13634.1 EMC87839.1 - 3.7 7.8 41.3 6.8 6.9 28.6 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region CBM_20 PF00686.14 EMC87840.1 - 1.4e-15 56.6 0.2 4.3e-15 55.0 0.1 1.8 2 0 0 2 2 2 1 Starch binding domain Reo_sigmaC PF04582.7 EMC87841.1 - 0.0002 20.6 28.2 0.0011 18.2 3.9 5.0 4 1 1 5 5 5 3 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 EMC87841.1 - 0.0026 17.1 4.6 0.0026 17.1 3.2 5.6 4 1 1 6 6 6 2 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.6 EMC87841.1 - 0.0048 16.7 1.0 0.0048 16.7 0.7 7.8 6 4 2 8 8 8 1 Flagella accessory protein C (FlaC) B2 PF11473.3 EMC87841.1 - 0.1 12.2 6.9 2.4 7.8 0.1 4.4 5 0 0 5 5 5 0 RNA binding protein B2 DUF869 PF05911.6 EMC87841.1 - 7.5 4.6 79.2 4.4 5.4 0.3 3.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) PIF PF05092.7 EMC87842.1 - 0.091 11.1 0.1 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Per os infectivity Gal-bind_lectin PF00337.17 EMC87843.1 - 4.2e-30 103.8 0.0 4.5e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin CIA30 PF08547.7 EMC87843.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Ank_5 PF13857.1 EMC87844.1 - 2.6e-12 46.5 0.1 7e-09 35.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC87844.1 - 2.9e-09 36.2 1.0 1.5e-06 27.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMC87844.1 - 1.4e-07 31.7 0.0 3.5e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC87844.1 - 9e-07 29.2 1.1 1.1e-05 25.8 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC87844.1 - 0.00014 21.7 0.1 0.04 14.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Septin PF00735.13 EMC87845.1 - 4.6e-99 330.9 1.3 4.6e-99 330.9 0.9 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMC87845.1 - 8.9e-07 28.8 0.5 2.3e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC87845.1 - 0.0011 19.0 0.7 0.0044 17.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 EMC87845.1 - 0.0016 17.8 0.0 0.0048 16.2 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 EMC87845.1 - 0.0022 18.0 0.4 0.0067 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EMC87845.1 - 0.0062 16.0 1.0 0.015 14.7 0.7 1.8 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 EMC87845.1 - 0.0097 15.3 3.6 1.3 8.3 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EMC87845.1 - 0.015 14.8 0.1 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EMC87845.1 - 0.029 14.8 1.7 0.061 13.8 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EMC87845.1 - 0.17 11.3 3.4 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EMC87845.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.6 2 2 0 2 2 1 0 ABC transporter Dynamin_N PF00350.18 EMC87845.1 - 0.27 11.0 9.3 3.8 7.2 0.1 3.4 2 1 0 2 2 2 0 Dynamin family DUF87 PF01935.12 EMC87845.1 - 0.55 10.0 9.2 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 Fzo_mitofusin PF04799.8 EMC87845.1 - 1 8.7 11.1 0.75 9.1 6.2 1.8 2 0 0 2 2 2 0 fzo-like conserved region IncA PF04156.9 EMC87845.1 - 2.6 7.6 13.9 4.6 6.7 9.6 1.4 1 0 0 1 1 1 0 IncA protein AAA_11 PF13086.1 EMC87845.1 - 3.8 7.0 11.9 7.5 6.0 7.9 1.7 1 1 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 EMC87846.1 - 3.7e-25 87.9 0.1 8.9e-25 86.7 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC87846.1 - 0.00096 19.0 2.5 0.0045 16.9 0.7 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 EMC87847.1 - 2.9e-17 62.4 0.4 2.9e-17 62.4 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain IL8 PF00048.15 EMC87848.1 - 1.5e-17 63.3 1.1 1.7e-17 63.1 0.7 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 EMC87849.1 - 3.7e-17 62.0 0.1 4.1e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like AdoMetDC_leader PF08132.6 EMC87849.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide IL8 PF00048.15 EMC87850.1 - 9.6e-06 25.4 0.1 1.1e-05 25.3 0.1 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Exo_endo_phos PF03372.18 EMC87851.1 - 3.3e-20 73.0 0.0 4.4e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EMC87851.1 - 2.7e-14 52.4 15.8 1.3e-09 37.4 1.1 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC87851.1 - 2.4e-10 40.0 8.6 2.4e-10 40.0 6.0 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EMC87851.1 - 8.9e-07 28.0 17.4 0.03 14.3 0.1 5.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC87851.1 - 0.0032 17.3 16.7 0.47 10.8 0.2 5.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EMC87851.1 - 0.77 10.0 13.5 6.7 7.1 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat MRL1 PF13003.2 EMC87853.1 - 2.8e-18 66.0 0.1 5.5e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L1 Ribosomal_L1 PF00687.16 EMC87853.1 - 1.5e-15 57.1 0.3 1.8e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cornifin PF02389.10 EMC87854.1 - 0.00018 21.3 22.7 0.00031 20.5 15.7 1.4 1 1 0 1 1 1 1 Cornifin (SPRR) family Antitoxin-MazE PF04014.13 EMC87854.1 - 0.0054 16.4 0.8 24 4.8 0.0 4.0 3 2 1 4 4 4 2 Antidote-toxin recognition MazE TRAPPC9-Trs120 PF08626.6 EMC87856.1 - 1.7e-10 39.0 0.0 2.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit UCH_1 PF13423.1 EMC87857.1 - 4.7e-28 98.4 0.0 6.4e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3456 PF11938.3 EMC87858.1 - 1.2e-38 132.4 0.5 1.4e-38 132.2 0.3 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.12 EMC87858.1 - 0.021 14.8 0.1 0.1 12.6 0.0 2.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 DUF72 PF01904.13 EMC87858.1 - 0.091 12.4 0.0 0.29 10.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF72 Citrate_synt PF00285.16 EMC87859.1 - 1.4e-80 270.6 0.0 1.6e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Pkinase PF00069.20 EMC87860.1 - 5.2e-11 42.1 0.0 5.6e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87860.1 - 0.0002 20.5 0.0 0.00024 20.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC87861.1 - 4.6e-57 193.1 0.1 5.4e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87861.1 - 5.3e-27 94.5 0.0 6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC87861.1 - 5e-06 25.7 0.1 6.5e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC87861.1 - 0.00093 18.9 0.0 0.0066 16.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC87861.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EMC87861.1 - 0.0057 15.6 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3890 PF13029.1 EMC87861.1 - 0.05 13.6 0.4 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) 7tm_1 PF00001.16 EMC87863.1 - 3.2e-20 72.3 4.3 3.3e-20 72.3 3.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC87863.1 - 1.4e-19 70.2 2.8 1.4e-19 70.2 1.9 1.7 2 0 0 2 2 2 1 Olfactory receptor ATP-synt_E PF05680.7 EMC87864.1 - 3.5e-18 65.3 0.1 4.1e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain Trichoplein PF13868.1 EMC87864.1 - 0.1 10.9 7.6 0.13 10.6 5.3 1.0 1 0 0 1 1 1 0 Tumour suppressor, Mitostatin DUF1211 PF06736.6 EMC87865.1 - 5.9e-57 189.8 5.8 2.9e-32 110.6 0.0 3.3 4 1 0 4 4 4 2 Protein of unknown function (DUF1211) Chordopox_A13L PF05961.6 EMC87865.1 - 0.084 12.8 0.3 0.084 12.8 0.2 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Pkinase PF00069.20 EMC87866.1 - 1.4e-51 175.1 0.0 2.2e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87866.1 - 1.7e-29 102.7 0.0 2.9e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PTEN_C2 PF10409.4 EMC87866.1 - 7e-27 93.7 0.0 1.6e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.26 EMC87866.1 - 1.8e-06 27.5 0.0 4.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Kinase-like PF14531.1 EMC87866.1 - 2.5e-06 26.6 0.0 8.9e-05 21.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Y_phosphatase PF00102.22 EMC87866.1 - 0.0015 17.9 3.0 0.0025 17.2 0.2 2.4 2 1 1 3 3 3 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC87866.1 - 0.0055 16.2 0.3 0.018 14.6 0.2 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Seadorna_VP7 PF07387.6 EMC87866.1 - 0.093 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMC87866.1 - 0.22 11.2 0.0 0.47 10.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family IN_DBD_C PF00552.16 EMC87867.1 - 2.8e-08 33.0 1.5 5.1e-08 32.2 1.0 1.5 1 0 0 1 1 1 1 Integrase DNA binding domain SNF2_N PF00176.18 EMC87869.1 - 1.3e-74 250.6 1.0 2.8e-74 249.6 0.7 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EMC87869.1 - 2.4e-33 114.3 0.9 2.4e-33 114.3 0.7 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EMC87869.1 - 1.8e-27 94.7 8.5 5.3e-16 58.0 0.0 4.2 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EMC87869.1 - 6.3e-14 51.5 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RIO1 PF01163.17 EMC87870.1 - 4.4e-53 179.4 2.1 1.5e-52 177.7 1.5 1.9 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EMC87870.1 - 5.9e-34 116.0 2.9 4.2e-33 113.2 0.2 2.7 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 EMC87870.1 - 5.4e-09 36.1 4.1 0.00025 20.8 0.8 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC87870.1 - 5.4e-08 32.1 1.2 1.1e-06 27.9 0.8 2.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EMC87870.1 - 0.00091 18.5 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 EMC87870.1 - 0.06 12.4 2.6 0.039 13.1 0.3 1.8 2 0 0 2 2 2 0 Protein kinase domain MarR_2 PF12802.2 EMC87870.1 - 0.12 12.0 0.1 0.7 9.6 0.0 2.2 3 0 0 3 3 3 0 MarR family SH2 PF00017.19 EMC87871.1 - 8.4e-18 63.9 0.1 1.3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain zf-RING_2 PF13639.1 EMC87872.1 - 1.8e-14 53.2 9.7 3.9e-14 52.1 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC87872.1 - 2.1e-08 34.1 6.1 2.1e-08 34.1 4.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMC87872.1 - 1.6e-07 30.8 7.5 1.6e-07 30.8 5.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC87872.1 - 6.3e-07 28.9 9.2 1.2e-06 28.0 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87872.1 - 6.5e-07 28.9 7.6 1.3e-06 27.9 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC87872.1 - 1.1e-06 28.5 9.9 2.6e-06 27.3 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC87872.1 - 0.0011 18.7 3.2 0.0011 18.7 2.2 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMC87872.1 - 0.1 12.6 9.5 0.2 11.7 6.6 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EMC87872.1 - 0.81 9.6 7.5 2.6 8.0 5.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EMC87872.1 - 1.7 8.3 7.3 4.5 6.9 5.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PRY PF13765.1 EMC87873.1 - 1.5e-08 34.0 0.1 1.5e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 SPRY-associated domain UPF0137 PF03677.8 EMC87873.1 - 0.11 11.9 3.7 0.17 11.3 2.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) SPRY PF00622.23 EMC87874.1 - 2.5e-11 43.7 0.0 3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 SPRY domain NeuB PF03102.9 EMC87875.1 - 5.9e-80 267.8 0.0 7.2e-80 267.6 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.7 EMC87875.1 - 1.4e-09 38.1 0.2 2.9e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 SAF domain SAF_2 PF13144.1 EMC87875.1 - 0.0014 18.1 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 SAF-like DUF849 PF05853.7 EMC87875.1 - 0.012 14.4 0.1 0.53 9.1 0.0 2.3 1 1 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) Clathrin_lg_ch PF01086.12 EMC87876.1 - 3.1e-65 220.2 9.4 3.5e-65 220.0 6.5 1.0 1 0 0 1 1 1 1 Clathrin light chain CENP-Q PF13094.1 EMC87876.1 - 0.0049 16.9 10.5 0.0092 16.0 7.3 1.5 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Myc-LZ PF02344.10 EMC87876.1 - 0.022 14.3 3.7 0.038 13.6 2.5 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain TBCA PF02970.11 EMC87876.1 - 0.099 12.7 6.9 0.25 11.4 4.8 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF2262 PF10020.4 EMC87876.1 - 0.18 11.9 4.9 0.26 11.4 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) APG6 PF04111.7 EMC87876.1 - 0.27 10.2 6.8 0.37 9.8 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Epimerase_2 PF02350.14 EMC87877.1 - 4.8e-73 245.9 0.1 7.9e-73 245.2 0.1 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase ROK PF00480.15 EMC87877.1 - 3.2e-39 134.6 1.8 1e-38 132.9 0.5 2.2 2 0 0 2 2 2 1 ROK family BcrAD_BadFG PF01869.15 EMC87877.1 - 4.5e-05 22.8 1.4 0.22 10.7 0.2 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 EMC87877.1 - 0.0021 17.4 0.0 0.0051 16.1 0.0 1.6 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 EMC87877.1 - 0.0032 16.8 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DRTGG PF07085.7 EMC87877.1 - 0.0035 16.9 0.2 0.012 15.2 0.1 1.9 1 0 0 1 1 1 1 DRTGG domain PLDc_3 PF13918.1 EMC87878.1 - 1.1e-35 122.7 0.0 1.8e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.1 EMC87878.1 - 9.7e-22 77.0 0.6 1.2e-12 47.7 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMC87878.1 - 7.7e-14 50.9 3.8 7.3e-09 35.1 0.5 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif CEP170_C PF15308.1 EMC87879.1 - 0 1021.6 52.0 0 1021.6 36.1 2.9 3 1 0 3 3 3 1 CEP170 C-terminus FHA PF00498.21 EMC87879.1 - 1.9e-17 63.1 0.1 5.6e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.20 EMC87880.1 - 1.2e-75 253.9 0.0 1.8e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87880.1 - 7e-36 123.6 0.0 1.1e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EMC87880.1 - 1.7e-13 50.6 0.6 4.4e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 EMC87880.1 - 4e-08 32.5 0.0 1.8e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EMC87880.1 - 2.6e-07 31.0 3.0 6.5e-07 29.7 2.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.1 EMC87880.1 - 0.0001 22.5 1.6 0.00067 19.8 1.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Seadorna_VP7 PF07387.6 EMC87880.1 - 0.038 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMC87880.1 - 0.073 12.7 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Adenylsucc_synt PF00709.16 EMC87882.1 - 7.7e-148 492.6 0.0 8.7e-148 492.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase FH2 PF02181.18 EMC87883.1 - 0.00014 20.9 1.5 0.00014 20.9 1.0 1.4 2 0 0 2 2 2 1 Formin Homology 2 Domain DUF3113 PF11310.3 EMC87883.1 - 0.083 12.5 0.5 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Ku_C PF03730.9 EMC87883.1 - 4 8.0 8.4 4.6 7.8 5.1 1.6 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm DUF1282 PF06930.7 EMC87884.1 - 0.028 14.1 2.5 0.045 13.4 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) SHR3_chaperone PF08229.6 EMC87884.1 - 0.24 10.3 4.5 0.034 13.0 0.3 1.9 2 1 0 2 2 2 0 ER membrane protein SH3 Yip1 PF04893.12 EMC87884.1 - 3.5 7.0 11.1 9.9 5.6 7.7 1.8 1 1 0 1 1 1 0 Yip1 domain RskA PF10099.4 EMC87885.1 - 0.0075 16.0 1.2 0.015 15.0 0.6 1.6 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DUF4131 PF13567.1 EMC87885.1 - 0.026 13.9 0.1 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1192 PF06698.6 EMC87885.1 - 0.056 13.2 1.7 2 8.2 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF3470 PF11953.3 EMC87885.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) Vinculin PF01044.14 EMC87885.1 - 0.07 11.1 3.5 0.1 10.5 2.4 1.1 1 0 0 1 1 1 0 Vinculin family CcmH PF03918.9 EMC87885.1 - 0.087 11.8 1.6 0.099 11.6 0.1 1.8 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF2681 PF10883.3 EMC87885.1 - 0.11 12.7 3.3 11 6.3 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) AAA_32 PF13654.1 EMC87885.1 - 0.33 9.5 5.4 0.57 8.7 3.7 1.3 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 EMC87886.1 - 9e-61 205.4 0.0 1.6e-60 204.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Asparaginase PF00710.15 EMC87888.1 - 1.3e-111 372.5 0.0 2.1e-111 371.7 0.0 1.4 2 0 0 2 2 2 1 Asparaginase Ank_2 PF12796.2 EMC87888.1 - 3e-21 75.5 0.0 1.2e-18 67.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC87888.1 - 3.8e-19 68.6 0.2 6.6e-12 45.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC87888.1 - 4.2e-15 55.4 1.0 8.8e-11 41.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC87888.1 - 1.7e-14 52.7 0.0 1.1e-08 34.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EMC87888.1 - 1.3e-11 43.5 0.5 1.4e-06 27.9 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat HA2 PF04408.18 EMC87889.1 - 2.4e-16 59.6 0.0 5.8e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) TUDOR PF00567.19 EMC87889.1 - 5e-15 55.4 0.0 1.4e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 Tudor domain Helicase_C PF00271.26 EMC87889.1 - 5.5e-12 45.3 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RD3 PF14473.1 EMC87890.1 - 4.6e-49 165.2 1.7 6.2e-49 164.8 1.2 1.1 1 0 0 1 1 1 1 RD3 protein Taxilin PF09728.4 EMC87890.1 - 0.025 13.6 0.2 0.031 13.3 0.2 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Mit_proteolip PF08039.6 EMC87891.1 - 7.3e-12 45.0 2.4 7.4e-12 45.0 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial proteolipid Ank PF00023.25 EMC87892.1 - 5.5e-19 66.9 1.3 5.1e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMC87892.1 - 1e-17 64.2 0.1 2.1e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC87892.1 - 6.1e-14 52.0 0.4 1.4e-09 38.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 EMC87892.1 - 8.7e-14 50.6 1.5 1.7e-13 49.6 1.1 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.1 EMC87892.1 - 1.4e-12 46.5 1.2 8.9e-06 25.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.1 EMC87892.1 - 5.5e-12 45.0 0.2 1.1e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.1 EMC87892.1 - 1.7e-11 43.9 1.9 2.3e-09 37.2 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_2 PF07653.12 EMC87892.1 - 6.9e-10 38.2 0.0 1.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FYVE PF01363.16 EMC87893.1 - 1.3e-11 44.1 23.9 2.5e-11 43.2 16.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Rad51 PF08423.6 EMC87894.1 - 2.2e-27 95.5 0.0 1.6e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMC87894.1 - 9.3e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EMC87894.1 - 2.5e-05 23.4 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EMC87894.1 - 2.9e-05 23.2 0.2 0.025 13.6 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein RNA_pol_A_CTD PF03118.10 EMC87894.1 - 0.0016 17.8 0.1 0.0029 16.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH_5 PF14520.1 EMC87894.1 - 0.012 15.7 0.1 0.036 14.2 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2315 PF10231.4 EMC87895.1 - 2.3e-24 85.7 0.1 2.4e-24 85.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) V-ATPase_G PF03179.10 EMC87895.1 - 0.039 14.2 0.9 0.046 14.0 0.6 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit BAG PF02179.11 EMC87896.1 - 2.5e-62 206.9 25.4 2.8e-16 59.3 2.9 5.1 5 0 0 5 5 5 5 BAG domain Snapin_Pallidin PF14712.1 EMC87896.1 - 0.83 9.9 13.1 0.69 10.2 3.1 3.3 3 0 0 3 3 3 0 Snapin/Pallidin DUF4061 PF13270.1 EMC87896.1 - 1.7 8.7 7.2 1.4 9.1 0.7 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4061) GCD14 PF08704.5 EMC87897.1 - 1.7e-110 368.3 0.0 2e-110 368.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EMC87897.1 - 2.9e-07 30.1 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC87897.1 - 9.6e-07 29.3 0.0 1.5e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC87897.1 - 2.2e-05 24.4 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMC87897.1 - 2.2e-05 24.1 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.1 EMC87897.1 - 0.0036 16.8 0.6 0.0074 15.8 0.4 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.1 EMC87897.1 - 0.0085 16.9 0.0 0.015 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMC87897.1 - 0.0098 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EMC87897.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMC87897.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMC87897.1 - 0.028 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EMC87897.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ATP-gua_Ptrans PF00217.14 EMC87898.1 - 1.6e-92 309.2 0.0 2.3e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 EMC87898.1 - 4.8e-35 119.5 0.0 7e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain eIF-5_eIF-2B PF01873.12 EMC87899.1 - 8.6e-47 157.8 0.6 4.4e-46 155.6 0.1 2.1 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 EMC87899.1 - 8.4e-25 86.5 5.7 8.4e-25 86.5 3.9 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PGA2 PF07543.7 EMC87899.1 - 4.4 7.0 11.7 3.9 7.2 0.5 2.8 2 0 0 2 2 2 0 Protein trafficking PGA2 LIN37 PF15306.1 EMC87899.1 - 5.8 6.8 9.0 0.93 9.4 2.7 2.2 2 0 0 2 2 2 0 LIN37 Sec6 PF06046.8 EMC87900.1 - 0.00021 19.5 0.3 0.0015 16.6 0.0 2.0 2 1 0 2 2 2 1 Exocyst complex component Sec6 DUF2702 PF10863.3 EMC87900.1 - 0.12 12.0 0.3 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) Sec6 PF06046.8 EMC87902.1 - 1.7e-79 267.4 14.7 2.2e-79 267.0 10.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 Sec6 PF06046.8 EMC87903.1 - 6.7e-74 248.9 5.3 9.6e-74 248.4 3.7 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Laps PF10169.4 EMC87903.1 - 0.027 14.7 0.9 0.057 13.6 0.6 1.5 1 0 0 1 1 1 0 Learning-associated protein DUF433 PF04255.9 EMC87903.1 - 0.068 12.6 0.2 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF433) DUF479 PF04336.7 EMC87903.1 - 0.24 11.5 3.2 2.9 8.0 0.2 3.8 2 1 1 3 3 3 0 Protein of unknown function, DUF479 CNH PF00780.17 EMC87904.1 - 5.8e-69 232.5 0.1 1.2e-68 231.5 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 EMC87904.1 - 1e-54 185.4 1.9 1.3e-54 185.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87904.1 - 7.7e-29 100.5 0.0 7.7e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DMPK_coil PF08826.5 EMC87904.1 - 1.9e-26 91.6 12.6 1.9e-26 91.6 8.7 9.2 7 2 3 10 10 10 1 DMPK coiled coil domain like C1_1 PF00130.17 EMC87904.1 - 1.3e-09 37.6 5.4 2.7e-09 36.5 3.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMC87904.1 - 0.00077 19.9 1.8 0.00077 19.9 1.2 2.3 2 0 0 2 2 1 1 Protein kinase C terminal domain PBD PF00786.23 EMC87904.1 - 0.001 19.4 0.0 0.0045 17.3 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Myosin_tail_1 PF01576.14 EMC87904.1 - 0.02 12.6 104.6 0.05 11.3 23.5 2.1 1 1 1 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 EMC87904.1 - 0.12 11.5 15.3 1.4 8.0 1.1 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein APH PF01636.18 EMC87904.1 - 1 9.0 3.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Filament PF00038.16 EMC87904.1 - 3 7.2 89.3 0.3 10.4 13.2 4.6 1 1 4 5 5 5 0 Intermediate filament protein Baculo_PEP_C PF04513.7 EMC87904.1 - 4.4 7.1 16.6 2.4 7.9 0.4 4.3 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Amnionless PF14828.1 EMC87905.1 - 5.7e-88 295.3 0.1 6.3e-88 295.1 0.1 1.0 1 0 0 1 1 1 1 Amnionless VWC PF00093.13 EMC87905.1 - 0.56 10.3 8.3 1.6 8.9 5.7 1.8 1 0 0 1 1 1 0 von Willebrand factor type C domain MATH PF00917.21 EMC87906.1 - 1.7e-28 99.2 0.0 1.3e-27 96.3 0.0 2.4 2 0 0 2 2 2 1 MATH domain zf-TRAF PF02176.13 EMC87906.1 - 5.9e-25 87.4 24.2 2.6e-16 59.7 5.4 4.4 2 2 2 4 4 3 2 TRAF-type zinc finger FliJ PF02050.11 EMC87906.1 - 0.0013 18.7 9.0 0.0025 17.8 6.3 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein Sina PF03145.11 EMC87906.1 - 0.0021 17.7 9.1 0.0074 15.9 0.8 3.9 2 1 3 5 5 4 2 Seven in absentia protein family zf-C3HC4_2 PF13923.1 EMC87906.1 - 0.0039 17.1 14.4 0.0039 17.1 10.0 3.1 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC87906.1 - 0.0045 16.6 14.9 0.0045 16.6 10.3 3.2 3 2 0 3 3 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC87906.1 - 0.0055 16.3 15.8 0.0055 16.3 11.0 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) BLOC1_2 PF10046.4 EMC87906.1 - 0.016 15.3 7.1 0.44 10.7 3.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C3HC4_4 PF15227.1 EMC87906.1 - 0.016 15.0 12.8 0.016 15.0 8.9 2.7 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING HrpB7 PF09486.5 EMC87906.1 - 0.02 14.8 2.8 0.056 13.3 0.2 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-RING_6 PF14835.1 EMC87906.1 - 0.088 12.6 6.4 0.095 12.4 3.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein IncA PF04156.9 EMC87906.1 - 0.11 12.0 12.3 0.2 11.2 8.5 1.4 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EMC87906.1 - 0.15 11.2 14.0 0.025 13.7 6.4 2.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EMC87906.1 - 0.16 9.8 7.3 0.22 9.3 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EMC87906.1 - 0.24 11.2 17.5 0.1 12.4 7.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Med9 PF07544.8 EMC87906.1 - 0.24 11.1 9.9 1 9.1 3.6 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin_1 PF12718.2 EMC87906.1 - 0.36 10.6 14.0 1.1 9.0 9.7 1.9 1 1 0 1 1 1 0 Tropomyosin like DUF3450 PF11932.3 EMC87906.1 - 0.73 9.0 8.3 1.2 8.3 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.6 EMC87906.1 - 1 8.7 8.2 0.18 11.2 2.6 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 SNARE PF05739.14 EMC87906.1 - 1.1 8.9 7.6 0.39 10.4 2.5 2.1 2 0 0 2 2 2 0 SNARE domain ADIP PF11559.3 EMC87906.1 - 1.6 8.6 18.5 0.26 11.1 8.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EMC87906.1 - 2.2 7.3 5.5 1.8 7.6 1.1 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Myb_DNA-binding PF00249.26 EMC87908.1 - 8.4e-17 60.9 0.2 1.6e-08 34.4 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.19 EMC87908.1 - 0.00017 22.1 2.7 0.00021 21.8 0.0 2.6 2 1 0 2 2 2 1 ELM2 domain Myb_DNA-bind_6 PF13921.1 EMC87908.1 - 0.00039 20.4 3.0 0.46 10.6 0.1 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Tropomyosin_1 PF12718.2 EMC87908.1 - 0.11 12.3 13.7 0.3 10.9 9.5 1.7 1 0 0 1 1 1 0 Tropomyosin like Ank_5 PF13857.1 EMC87910.1 - 4.8e-08 32.9 0.3 6.7e-07 29.3 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC87910.1 - 5.3e-08 33.1 0.5 7.2e-06 26.3 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC87910.1 - 9.9e-08 32.2 0.1 1.1e-06 28.8 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMC87910.1 - 5.5e-07 29.0 1.9 1.8e-06 27.4 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EMC87910.1 - 0.02 15.0 1.4 0.29 11.5 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeat Med17 PF10156.4 EMC87911.1 - 0.03 12.6 1.3 0.85 7.8 0.1 2.0 2 0 0 2 2 2 0 Subunit 17 of Mediator complex AAA_8 PF12780.2 EMC87911.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Fer2 PF00111.22 EMC87913.1 - 0.15 11.8 0.8 0.72 9.6 0.7 2.0 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-C2H2 PF00096.21 EMC87914.1 - 0.056 13.8 0.2 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pkinase PF00069.20 EMC87915.1 - 1.6e-67 227.4 0.0 2e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87915.1 - 4.8e-30 104.5 0.0 7.5e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC87915.1 - 0.00098 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC87915.1 - 0.089 11.8 0.1 0.19 10.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EMC87916.1 - 2.3e-16 58.9 12.0 8.3e-07 28.6 0.2 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 EMC87916.1 - 0.0013 18.3 0.3 1.7 8.4 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EMC87916.1 - 0.01 15.5 0.0 0.075 12.7 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A B56 PF01603.15 EMC87918.1 - 4e-177 588.8 11.7 5e-177 588.5 8.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) T4_deiodinase PF00837.12 EMC87919.1 - 1.8e-61 207.2 0.0 2e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase EGF PF00008.22 EMC87920.1 - 4.3e-31 106.4 87.3 8.5e-09 35.2 7.7 6.8 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 EMC87920.1 - 2.9e-12 45.8 46.3 0.0011 18.9 0.6 7.2 6 0 0 6 6 6 6 Human growth factor-like EGF EGF_2 PF07974.8 EMC87920.1 - 9.4e-12 44.8 100.8 0.006 16.7 6.3 6.4 6 0 0 6 6 6 6 EGF-like domain EGF_CA PF07645.10 EMC87920.1 - 0.1 12.5 77.2 0.15 12.0 6.3 6.7 3 2 2 5 5 5 0 Calcium-binding EGF domain Laminin_EGF PF00053.19 EMC87920.1 - 0.14 12.1 70.9 0.061 13.2 5.2 6.5 3 2 2 6 6 6 0 Laminin EGF-like (Domains III and V) Pilt PF15453.1 EMC87921.1 - 8.2e-07 29.0 13.7 8.2e-07 29.0 9.5 3.1 2 1 0 2 2 2 1 Protein incorporated later into Tight Junctions Homeobox PF00046.24 EMC87921.1 - 0.053 13.1 0.9 0.2 11.3 0.6 2.1 1 0 0 1 1 1 0 Homeobox domain V_ATPase_I PF01496.14 EMC87921.1 - 0.059 11.2 4.1 0.099 10.4 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMC87921.1 - 0.098 12.2 15.8 0.059 12.9 9.2 2.0 1 1 1 2 2 2 0 IncA protein DUF342 PF03961.8 EMC87921.1 - 0.34 9.2 6.5 0.59 8.4 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ApoO PF09769.4 EMC87921.1 - 1.1 8.9 5.4 0.26 11.0 0.3 2.4 2 1 0 2 2 2 0 Apolipoprotein O DUF1664 PF07889.7 EMC87921.1 - 1.4 8.7 5.7 0.99 9.2 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.10 EMC87921.1 - 4.5 7.2 18.1 0.067 13.2 4.6 3.2 3 1 0 3 3 3 0 Fez1 WD40 PF00400.27 EMC87922.1 - 1.4e-30 104.0 11.2 8.6e-08 31.7 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC87922.1 - 1.7e-09 37.6 0.0 0.00028 20.6 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMC87922.1 - 0.0051 15.0 0.1 0.042 11.9 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 tRNA-synt_1b PF00579.20 EMC87923.1 - 3.2e-23 82.2 0.0 5.6e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.15 EMC87923.1 - 2.4e-21 75.1 0.1 5.3e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 WHEP-TRS domain Mito_carr PF00153.22 EMC87925.1 - 2.3e-68 225.9 0.2 7.6e-24 83.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EMC87926.1 - 4.8e-67 221.7 1.9 8.7e-24 83.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 EMC87927.1 - 4.5e-19 67.5 22.9 2.5e-05 24.3 0.3 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC87927.1 - 1.3e-18 66.2 23.1 3e-08 33.5 0.1 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC87927.1 - 4.3e-14 51.7 17.6 0.00012 22.1 0.1 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger Transpos_assoc PF13963.1 EMC87927.1 - 0.0022 17.9 6.4 0.029 14.3 0.1 2.8 3 0 0 3 3 3 2 Transposase-associated domain zf-RING_3 PF14369.1 EMC87927.1 - 0.0056 16.6 2.8 0.5 10.4 0.0 3.3 3 0 0 3 3 3 1 zinc-finger zf-C2H2_jaz PF12171.3 EMC87927.1 - 0.0057 16.7 13.5 2.1 8.5 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EMC87927.1 - 0.0059 16.9 11.7 2 8.8 0.1 3.3 1 1 2 3 3 3 2 TRAF-type zinc finger CCAP PF11105.3 EMC87927.1 - 0.012 15.3 4.2 0.38 10.4 0.6 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Raffinose_syn PF05691.7 EMC87927.1 - 0.024 12.1 0.0 0.029 11.8 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 IBR PF01485.16 EMC87927.1 - 0.047 13.5 0.9 0.047 13.5 0.6 2.8 1 1 1 3 3 3 0 IBR domain CHORD PF04968.7 EMC87927.1 - 0.049 13.8 10.8 8 6.7 1.4 3.5 1 1 3 4 4 4 0 CHORD XPA_N PF01286.13 EMC87927.1 - 0.1 12.2 2.4 0.29 10.8 0.0 2.8 3 0 0 3 3 3 0 XPA protein N-terminal zf-CGNR PF11706.3 EMC87927.1 - 0.18 11.3 7.1 2.7 7.5 0.1 3.3 3 1 0 3 3 3 0 CGNR zinc finger zf-met PF12874.2 EMC87927.1 - 0.21 11.8 6.0 2.3 8.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC87927.1 - 1.4 8.8 0.1 1.4 8.8 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger FA_desaturase PF00487.19 EMC87928.1 - 4.2e-25 88.6 16.2 8e-25 87.7 11.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EMC87928.1 - 7.2e-06 25.1 0.4 2.7e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) WH1 PF00568.18 EMC87929.1 - 3.3e-35 120.1 0.5 4.9e-35 119.6 0.4 1.3 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.6 EMC87929.1 - 7.9e-24 82.6 5.2 7.9e-24 82.6 3.6 1.6 2 0 0 2 2 2 1 VASP tetramerisation domain Ran_BP1 PF00638.13 EMC87929.1 - 0.0018 18.3 0.2 0.0055 16.7 0.0 1.9 2 1 0 2 2 2 1 RanBP1 domain DUF3130 PF11328.3 EMC87929.1 - 0.06 13.3 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 HELP PF03451.9 EMC87930.1 - 4.2e-38 128.7 0.3 7.5e-38 127.9 0.2 1.4 1 0 0 1 1 1 1 HELP motif WD40 PF00400.27 EMC87930.1 - 4.1e-27 93.0 39.7 7e-05 22.5 0.2 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat DPPIV_N PF00930.16 EMC87930.1 - 0.019 13.5 0.0 0.044 12.3 0.0 1.6 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Macoilin PF09726.4 EMC87930.1 - 0.4 8.9 1.8 0.59 8.3 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EMC87930.1 - 0.5 10.7 4.0 0.41 11.0 1.7 1.7 2 0 0 2 2 2 0 SlyX Matrilin_ccoil PF10393.4 EMC87930.1 - 1.1 8.6 3.1 2.4 7.5 0.4 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin PIP49_C PF12260.3 EMC87931.1 - 1.3e-10 40.9 0.0 2.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Nodulin_late PF07127.6 EMC87931.1 - 1.3 9.2 3.8 1.1 9.3 0.9 2.1 2 0 0 2 2 2 0 Late nodulin protein GSDH PF07995.6 EMC87932.1 - 2.7e-40 138.4 0.0 3.4e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.9 EMC87932.1 - 5.4e-12 45.6 1.6 1.1e-11 44.6 1.1 1.4 1 0 0 1 1 1 1 Folate receptor family Cyclin_N PF00134.18 EMC87933.1 - 6.8e-17 61.2 5.0 2.2e-16 59.6 0.0 2.8 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC87933.1 - 0.0073 16.2 0.1 0.0073 16.2 0.1 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain eIF-3_zeta PF05091.7 EMC87933.1 - 1.6 7.2 9.8 2.1 6.8 6.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mitofilin PF09731.4 EMC87933.1 - 2 6.9 12.7 2.6 6.6 8.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Borrelia_P83 PF05262.6 EMC87933.1 - 4.8 5.3 8.3 1.1e+02 0.8 0.0 1.9 2 0 0 2 2 2 0 Borrelia P83/100 protein Hid1 PF12722.2 EMC87933.1 - 6.1 4.3 10.3 8.1 3.9 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleo_P87 PF07267.6 EMC87933.1 - 6.2 5.3 7.8 8.3 4.9 5.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4557 PF15101.1 EMC87933.1 - 7.2 6.3 13.6 12 5.6 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Rubis-subs-bind PF09273.6 EMC87934.1 - 1.7e-35 121.7 0.1 4.2e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EMC87934.1 - 2.2e-10 41.0 0.2 2.5e-09 37.6 0.0 2.6 3 0 0 3 3 3 1 SET domain zf-C2H2 PF00096.21 EMC87935.1 - 3.5e-10 39.6 25.4 5.9e-05 23.1 1.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC87935.1 - 1.1e-09 37.8 6.3 8.1e-07 28.7 0.1 4.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC87935.1 - 9.1e-06 25.7 1.8 9.1e-06 25.7 1.2 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC87935.1 - 0.00088 19.4 25.5 0.07 13.4 3.5 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger FYVE PF01363.16 EMC87935.1 - 0.038 13.8 9.4 0.11 12.4 0.7 3.3 3 0 0 3 3 3 0 FYVE zinc finger Daxx PF03344.10 EMC87935.1 - 0.44 8.9 15.1 0.61 8.5 10.5 1.1 1 0 0 1 1 1 0 Daxx Family zf-C2H2_2 PF12756.2 EMC87935.1 - 1.2 9.3 14.7 11 6.1 0.0 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 EMC87937.1 - 7e-17 61.4 0.1 3.5e-16 59.1 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87937.1 - 2.4e-08 33.3 0.1 1.9e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase EcKinase PF02958.15 EMC87937.1 - 0.0031 16.6 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EMC87937.1 - 0.02 14.6 0.1 0.099 12.3 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family PAP_central PF04928.12 EMC87938.1 - 2.3e-109 364.0 0.0 4.6e-109 363.1 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EMC87938.1 - 1.3e-36 125.4 1.9 3.2e-36 124.2 1.3 1.7 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EMC87938.1 - 3.2e-09 37.0 0.1 7.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain UPF0058 PF01893.11 EMC87939.1 - 0.0093 15.9 0.3 0.022 14.8 0.0 1.7 1 1 1 2 2 2 1 Uncharacterised protein family UPF0058 LAGLIDADG_1 PF00961.14 EMC87939.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 LAGLIDADG endonuclease DUF727 PF05303.7 EMC87940.1 - 1.8e-40 137.0 0.1 2.1e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Glyco_hydro_77 PF02446.12 EMC87940.1 - 0.023 13.3 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase 7tm_1 PF00001.16 EMC87941.1 - 9.9e-57 192.0 14.8 1.3e-56 191.6 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC87941.1 - 3.6e-07 29.6 14.7 2.6e-06 26.8 10.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF202 PF02656.10 EMC87941.1 - 6 7.1 7.1 3.6 7.8 0.9 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) 7tm_1 PF00001.16 EMC87942.1 - 6.4e-55 186.0 31.8 7.5e-55 185.8 22.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glutaredoxin PF00462.19 EMC87943.1 - 1.9e-05 24.5 0.2 0.00016 21.6 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF2639 PF11121.3 EMC87943.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) CH PF00307.26 EMC87944.1 - 2.1e-37 127.4 0.1 1.5e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC87944.1 - 2.6e-08 33.4 0.0 0.00029 20.4 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Pex14_N PF04695.8 EMC87944.1 - 0.15 12.1 0.8 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribonuclease_3 PF00636.21 EMC87946.1 - 4.7e-75 249.3 0.1 2e-48 163.5 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.17 EMC87946.1 - 1.5e-39 134.3 0.3 3.8e-39 133.0 0.1 1.8 2 0 0 2 2 2 1 PAZ domain Dicer_dimer PF03368.9 EMC87946.1 - 1.3e-30 104.9 0.0 4.8e-30 103.1 0.0 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 EMC87946.1 - 1.3e-25 89.8 0.0 3.4e-17 62.5 0.0 3.9 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 EMC87946.1 - 7.8e-18 64.1 0.0 2.1e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMC87946.1 - 1e-12 47.8 0.0 2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMC87946.1 - 2.2e-11 43.9 0.0 6.7e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EMC87946.1 - 0.0007 20.1 0.0 0.0031 18.0 0.0 2.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif Flavi_DEAD PF07652.9 EMC87946.1 - 0.11 12.3 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain Serpin PF00079.15 EMC87947.1 - 1.5e-114 382.9 0.4 1.7e-114 382.8 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4198 PF10670.4 EMC87947.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4198) Borrelia_orfA PF02414.10 EMC87947.1 - 0.25 10.4 3.3 0.2 10.7 0.9 1.8 2 0 0 2 2 2 0 Borrelia ORF-A Serpin PF00079.15 EMC87948.1 - 4.9e-116 387.8 0.5 5.5e-116 387.7 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC87949.1 - 5.2e-114 381.2 0.8 5.8e-114 381.0 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) JHBP PF06585.6 EMC87949.1 - 0.0054 15.5 1.4 0.11 11.2 0.0 2.3 2 0 0 2 2 2 2 Haemolymph juvenile hormone binding protein (JHBP) Serpin PF00079.15 EMC87950.1 - 8.1e-75 252.2 1.6 9e-75 252.1 1.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Fer4_12 PF13353.1 EMC87950.1 - 0.023 14.7 0.4 1.1 9.3 0.2 2.2 1 1 1 2 2 2 0 4Fe-4S single cluster domain Serpin PF00079.15 EMC87952.1 - 5.6e-121 404.1 5.1 6.3e-121 403.9 3.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 EMC87953.1 - 3.5e-103 345.5 7.4 4e-103 345.4 5.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) HEAT PF02985.17 EMC87954.1 - 1.2e-14 52.9 6.7 0.00017 21.3 0.1 7.5 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 EMC87954.1 - 1.9e-09 37.6 0.0 0.00017 21.8 0.1 5.1 3 2 0 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EMC87954.1 - 3.2e-05 24.2 4.0 1.2 9.5 0.0 4.7 3 1 3 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC87954.1 - 0.00049 20.4 3.4 0.38 11.3 0.1 5.0 4 2 1 5 5 5 1 HEAT-like repeat Arm PF00514.18 EMC87954.1 - 0.66 9.8 4.7 4.2 7.3 0.1 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.2 EMC87955.1 - 1.5e-73 243.1 10.5 1.3e-19 70.3 0.2 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EMC87955.1 - 1.1e-63 208.0 16.1 5e-07 29.2 0.0 11.4 10 1 1 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 EMC87955.1 - 3.4e-52 173.9 8.5 8.1e-10 38.9 0.0 8.8 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC87955.1 - 1.2e-47 155.1 12.1 0.00017 21.5 0.0 11.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 EMC87955.1 - 6.1e-41 137.5 17.1 2.9e-11 43.2 0.3 10.5 2 1 10 12 12 12 10 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC87955.1 - 1.3e-13 50.5 3.4 1.6e-12 47.0 3.4 2.0 2 0 0 2 2 2 1 SOCS box FAM181 PF15238.1 EMC87956.1 - 3.5e-77 260.4 17.9 5.6e-76 256.4 12.4 1.9 1 1 0 1 1 1 1 FAM181 PAT1 PF09770.4 EMC87956.1 - 0.084 11.1 2.9 0.1 10.8 2.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EphA2_TM PF14575.1 EMC87957.1 - 0.0046 17.3 0.3 0.0071 16.7 0.2 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.2 EMC87957.1 - 0.0068 15.6 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.1 EMC87957.1 - 0.0072 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF1191 PF06697.7 EMC87957.1 - 0.0083 14.9 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Mito_fiss_reg PF05308.6 EMC87957.1 - 0.016 14.5 3.1 0.02 14.3 2.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Herpes_gE PF02480.11 EMC87957.1 - 0.022 13.0 0.0 0.026 12.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAM163 PF15069.1 EMC87957.1 - 0.027 15.0 0.3 0.062 13.8 0.2 1.5 1 0 0 1 1 1 0 FAM163 family CD34_antigen PF06365.7 EMC87957.1 - 0.034 13.7 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family TRP PF06011.7 EMC87957.1 - 0.045 12.3 0.1 0.055 12.0 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel S1FA PF04689.8 EMC87957.1 - 0.047 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA FAM176 PF14851.1 EMC87957.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 FAM176 family gpUL132 PF11359.3 EMC87957.1 - 0.081 12.2 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 OATP PF03137.15 EMC87957.1 - 0.084 10.9 0.0 0.18 9.8 0.0 1.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Shisa PF13908.1 EMC87957.1 - 5 7.2 9.9 0.068 13.3 1.2 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator UNC-79 PF14776.1 EMC87958.1 - 4.4e-11 41.8 0.1 5.7e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 BTB PF00651.26 EMC87959.1 - 3.7e-25 88.0 0.4 6.8e-14 51.8 0.0 3.4 2 1 0 2 2 2 2 BTB/POZ domain BACK PF07707.10 EMC87959.1 - 1.5e-10 40.8 0.2 4.7e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch PHD PF00628.24 EMC87960.1 - 0.00074 19.1 4.7 0.00074 19.1 3.3 3.4 4 1 0 4 4 4 1 PHD-finger DUF4583 PF15190.1 EMC87961.1 - 2.7e-74 246.9 2.6 3e-74 246.7 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4583) DUF4064 PF13273.1 EMC87961.1 - 0.0028 17.7 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) AA_permease PF00324.16 EMC87961.1 - 0.031 12.6 0.2 0.042 12.1 0.1 1.2 1 0 0 1 1 1 0 Amino acid permease DUF4131 PF13567.1 EMC87961.1 - 0.065 12.6 7.0 0.028 13.8 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) GpcrRhopsn4 PF10192.4 EMC87961.1 - 0.23 10.6 0.1 0.23 10.6 0.1 2.1 2 1 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain DUF485 PF04341.7 EMC87961.1 - 2.2 8.0 6.7 1.6 8.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF485 Ins134_P3_kin PF05770.6 EMC87962.1 - 2.1e-115 385.0 0.2 2.6e-115 384.6 0.1 1.1 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase Rep_fac_C PF08542.6 EMC87962.1 - 0.086 12.8 0.1 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Replication factor C C-terminal domain Granin PF01271.12 EMC87963.1 - 5.4e-34 117.8 25.7 8.7e-22 77.5 14.4 3.0 2 1 1 3 3 3 2 Granin (chromogranin or secretogranin) Golgin_A5 PF09787.4 EMC87964.1 - 7.7e-158 526.1 62.6 7.7e-158 526.1 43.4 3.4 1 1 1 3 3 3 1 Golgin subfamily A member 5 AAA_27 PF13514.1 EMC87964.1 - 7 4.1 73.2 0.2 9.2 16.9 3.2 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.6 EMC87964.1 - 7.5 5.1 84.7 0.026 13.2 6.6 5.0 2 1 3 5 5 5 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EMC87964.1 - 9.3 6.1 95.6 0.12 12.1 19.0 4.9 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_C13 PF01650.13 EMC87965.1 - 4.8e-117 389.7 1.6 7.4e-117 389.1 1.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family Toxin_49 PF15529.1 EMC87965.1 - 0.095 12.6 0.6 0.29 11.0 0.0 2.1 3 0 0 3 3 3 0 Putative toxin 49 VPS9 PF02204.13 EMC87966.1 - 3.3e-28 97.7 0.1 3.3e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.18 EMC87966.1 - 1.2e-06 28.8 0.8 3.1e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.19 EMC87966.1 - 0.047 13.4 0.1 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 SH2 domain CPSF100_C PF13299.1 EMC87967.1 - 4.9e-44 150.3 0.8 3e-43 147.8 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EMC87967.1 - 3.3e-23 82.0 0.0 7.9e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EMC87967.1 - 4e-11 42.5 0.0 8.7e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EMC87967.1 - 9.3e-08 31.9 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NADH_oxidored PF08040.6 EMC87968.1 - 1.6e-33 114.0 0.1 1.8e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 MNLL subunit Josephin PF02099.12 EMC87969.1 - 8.3e-62 207.4 0.0 1.6e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 Josephin UIM PF02809.15 EMC87969.1 - 8.7e-14 49.7 21.0 5.7e-05 22.3 0.9 4.2 3 0 0 3 3 3 3 Ubiquitin interaction motif Lebercilin PF15619.1 EMC87970.1 - 0.0011 18.4 11.9 0.0011 18.4 8.2 16.3 7 3 7 15 15 15 4 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.7 EMC87970.1 - 0.017 15.3 0.7 0.017 15.3 0.5 18.1 13 8 4 17 17 17 0 Nucleopolyhedrovirus P10 protein EGF_CA PF07645.10 EMC87971.1 - 1.5e-46 156.0 88.2 2e-11 43.6 5.8 7.2 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.2 EMC87971.1 - 8.6e-32 108.4 60.6 1.1e-10 40.9 2.4 7.7 9 0 0 9 9 9 6 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EMC87971.1 - 1.7e-25 88.8 91.0 2.9e-08 33.7 6.7 8.1 8 1 0 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EMC87971.1 - 6.8e-13 48.3 64.6 4.3e-06 26.5 3.6 7.4 6 1 1 7 7 7 5 EGF domain EGF PF00008.22 EMC87971.1 - 1.1e-08 34.9 84.4 7.3e-05 22.6 5.2 8.4 8 2 0 8 8 8 4 EGF-like domain C2 PF00168.25 EMC87972.1 - 3.7e-11 42.7 0.0 9.3e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain SMK-1 PF04802.10 EMC87973.1 - 1.5e-84 282.3 9.2 2.6e-81 271.7 5.3 3.1 3 0 0 3 3 3 2 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 EMC87973.1 - 0.00034 20.2 0.0 0.00078 19.1 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.13 EMC87973.1 - 0.0058 16.6 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 RanBP1 domain Collagen PF01391.13 EMC87973.1 - 0.026 14.0 1.8 0.041 13.4 1.2 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.16 EMC87974.1 - 1.9e-45 155.0 19.8 1.9e-45 155.0 13.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC87974.1 - 3.5e-05 23.0 17.4 3.5e-05 23.0 12.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4392 PF14336.1 EMC87975.1 - 8.6e-92 307.0 0.0 1.2e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.7 EMC87975.1 - 2.2e-52 176.4 0.1 4.5e-52 175.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Pkinase PF00069.20 EMC87976.1 - 1.9e-140 466.4 0.4 1.9e-70 237.0 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC87976.1 - 6.9e-68 228.5 0.1 5.6e-34 117.3 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMC87976.1 - 1.1e-15 57.3 0.0 2.9e-06 26.4 0.0 3.3 3 1 0 3 3 3 2 Kinase-like APH PF01636.18 EMC87976.1 - 2.1e-13 50.5 4.0 9.6e-05 22.2 0.0 4.3 2 2 2 4 4 4 4 Phosphotransferase enzyme family Kdo PF06293.9 EMC87976.1 - 3.7e-13 48.9 0.3 2.5e-09 36.4 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EMC87976.1 - 7.6e-09 35.9 0.4 7.6e-09 35.9 0.3 2.3 3 0 0 3 3 3 1 Protein kinase C terminal domain RIO1 PF01163.17 EMC87976.1 - 3.9e-07 29.6 1.6 5.2e-05 22.6 0.1 2.5 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 EMC87976.1 - 0.001 18.7 1.4 0.02 14.4 0.0 3.0 3 0 0 3 3 3 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EMC87976.1 - 0.0041 16.4 6.5 0.03 13.6 0.0 3.5 3 1 0 4 4 4 1 PhoP regulatory network protein YrbL DUF2087 PF09860.4 EMC87976.1 - 0.045 13.5 1.0 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) EF-hand_1 PF00036.27 EMC87977.1 - 1.7e-43 142.5 10.0 3.2e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC87977.1 - 8.9e-39 131.4 3.9 1.3e-21 76.4 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC87977.1 - 5.9e-36 121.8 10.2 4.3e-17 61.4 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMC87977.1 - 1.4e-31 105.5 5.4 1.1e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC87977.1 - 2.9e-28 95.9 5.4 6.2e-07 28.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMC87977.1 - 8.8e-15 54.3 0.1 2.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC87977.1 - 2.2e-10 40.2 0.4 4.2e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC87977.1 - 1.2e-08 34.9 0.0 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EMC87977.1 - 6e-07 29.3 1.6 8.2e-06 25.7 0.2 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EMC87977.1 - 1.3e-06 27.9 0.0 0.18 11.4 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.6 EMC87977.1 - 0.00058 19.3 1.4 0.00068 19.0 1.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 EMC87977.1 - 0.0011 18.7 0.5 0.21 11.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 EMC87977.1 - 0.0013 18.3 0.1 0.036 13.6 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 EMC87977.1 - 0.015 15.3 1.7 2 8.4 0.1 2.5 3 0 0 3 3 2 0 RNA polymerase Rpb4 DUF3349 PF11829.3 EMC87977.1 - 0.016 15.5 0.4 13 6.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Poly_export PF02563.11 EMC87977.1 - 0.049 13.4 0.1 2.8 7.7 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 EMC87977.1 - 0.071 12.8 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 EMC87977.1 - 0.079 12.5 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 EMC87977.1 - 0.083 13.2 0.9 15 6.0 0.0 2.5 1 1 1 2 2 2 0 Toprim-like Tenui_NCP PF04876.7 EMC87977.1 - 0.098 12.1 0.1 0.96 8.9 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF1880 PF08976.6 EMC87977.1 - 0.12 12.4 0.0 2.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) CMD PF02627.15 EMC87977.1 - 0.19 11.5 1.0 4.9 7.0 0.0 2.8 2 2 2 4 4 3 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 EMC87977.1 - 2.8 8.3 6.3 60 4.1 0.6 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella NRDE-2 PF08424.5 EMC87978.1 - 2.1e-108 362.0 22.9 5.9e-108 360.5 2.0 4.2 4 1 1 5 5 5 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EMC87978.1 - 4.2e-09 36.2 0.8 0.56 10.9 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87978.1 - 0.00089 19.5 1.0 2.1 8.7 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87978.1 - 0.0051 17.4 0.6 10 6.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87978.1 - 0.56 10.5 6.3 76 3.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMC87978.1 - 1.2 9.7 4.3 89 3.8 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.24 EMC87979.1 - 2.2e-37 128.1 0.0 5.8e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC87979.1 - 9.1e-07 29.0 0.0 0.00011 22.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC87979.1 - 1.2e-05 25.1 0.2 9.7e-05 22.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EMC87979.1 - 2.6e-05 23.2 0.0 4.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EMC87979.1 - 2.8e-05 23.2 0.0 5.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMC87979.1 - 5.5e-05 23.1 0.0 0.00017 21.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMC87979.1 - 0.00014 21.9 0.0 0.0017 18.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMC87979.1 - 0.00041 21.1 0.2 0.0026 18.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMC87979.1 - 0.00054 19.4 0.1 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein SKI PF01202.17 EMC87979.1 - 0.0013 18.5 0.0 1.7 8.5 0.0 2.7 2 1 0 2 2 2 2 Shikimate kinase AAA_19 PF13245.1 EMC87979.1 - 0.0015 18.2 0.2 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMC87979.1 - 0.0017 18.6 0.1 0.0054 17.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EMC87979.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMC87979.1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EMC87979.1 - 0.0028 17.2 0.2 0.041 13.4 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMC87979.1 - 0.003 17.5 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMC87979.1 - 0.0044 16.6 0.3 0.03 13.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMC87979.1 - 0.0051 16.4 0.2 0.8 9.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMC87979.1 - 0.0052 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EMC87979.1 - 0.011 14.5 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 EMC87979.1 - 0.011 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EMC87979.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMC87979.1 - 0.015 14.6 0.6 0.1 11.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EMC87979.1 - 0.017 14.3 0.0 0.044 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EMC87979.1 - 0.025 13.7 0.1 0.21 10.6 0.0 2.3 2 1 1 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 EMC87979.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EMC87979.1 - 0.031 13.1 0.0 0.069 11.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EMC87979.1 - 0.041 13.5 0.1 0.22 11.1 0.0 2.2 2 1 1 3 3 2 0 NACHT domain Sigma54_activat PF00158.21 EMC87979.1 - 0.045 13.2 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DivIC PF04977.10 EMC87979.1 - 0.061 12.8 0.2 1.8 8.0 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator AAA_30 PF13604.1 EMC87979.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMC87979.1 - 0.088 13.1 0.0 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 EMC87979.1 - 0.091 11.6 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EMC87979.1 - 0.22 11.8 2.1 19 5.5 0.4 2.6 2 0 0 2 2 2 0 AAA domain Ion_trans_2 PF07885.11 EMC87980.1 - 1.2e-20 72.9 20.6 3.4e-15 55.4 6.1 2.3 2 0 0 2 2 2 2 Ion channel Presenilin PF01080.12 EMC87980.1 - 0.0001 21.2 3.3 0.00015 20.7 2.3 1.2 1 0 0 1 1 1 1 Presenilin Bap31 PF05529.7 EMC87980.1 - 0.011 15.1 0.9 3.5 7.0 0.0 3.1 2 1 0 3 3 3 0 B-cell receptor-associated protein 31-like FtsX PF02687.16 EMC87980.1 - 2.6 7.8 7.9 4.1 7.1 0.3 2.4 2 0 0 2 2 2 0 FtsX-like permease family Tyr-DNA_phospho PF06087.7 EMC87981.1 - 9.1e-129 429.9 0.0 1.1e-128 429.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Fork_head PF00250.13 EMC87982.1 - 4e-36 122.9 0.2 5.9e-36 122.3 0.2 1.2 1 0 0 1 1 1 1 Fork head domain TPR_11 PF13414.1 EMC87983.1 - 1.6e-24 85.3 30.8 1.4e-08 34.2 0.5 5.3 3 1 3 6 6 6 6 TPR repeat TPR_2 PF07719.12 EMC87983.1 - 6.3e-23 78.8 18.8 0.00067 19.3 0.0 8.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMC87983.1 - 2.1e-22 77.7 17.5 0.00069 19.1 0.2 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMC87983.1 - 2.3e-21 75.5 14.4 2.9e-06 27.1 0.1 5.5 2 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMC87983.1 - 3.1e-17 60.9 6.2 0.0099 15.5 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC87983.1 - 2.2e-15 55.7 6.1 0.014 15.9 0.0 7.4 3 3 6 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC87983.1 - 3.8e-15 56.0 8.9 2.4e-06 28.0 0.0 5.5 2 1 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC87983.1 - 1.2e-14 54.4 6.6 0.0026 18.0 0.0 5.8 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC87983.1 - 6.4e-14 50.5 9.3 0.002 17.8 0.0 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMC87983.1 - 7.7e-09 35.0 12.3 0.0093 16.0 0.2 7.7 7 1 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC87983.1 - 6.8e-07 29.3 13.0 0.67 10.5 0.3 6.9 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMC87983.1 - 6.9e-06 25.3 4.0 2.8e-05 23.3 0.7 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC87983.1 - 8.6e-06 25.8 17.7 0.01 15.9 2.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EMC87983.1 - 2.3e-05 24.1 8.5 0.023 14.6 0.6 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC87983.1 - 2.4e-05 24.0 2.5 4.5 7.1 0.1 4.8 2 2 3 5 5 5 1 Tetratricopeptide repeat WD40 PF00400.27 EMC87984.1 - 7.7e-72 234.8 74.0 5.2e-05 22.9 0.0 27.1 28 0 0 28 28 28 18 WD domain, G-beta repeat HELP PF03451.9 EMC87984.1 - 6.2e-29 99.3 0.3 1.6e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 HELP motif Nucleoporin_N PF08801.6 EMC87984.1 - 1.1e-05 24.4 0.0 1.2 7.8 0.0 4.2 3 1 1 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EMC87984.1 - 0.0008 17.8 9.7 1.5 6.9 0.0 6.4 7 1 0 8 8 8 2 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 EMC87984.1 - 0.0011 18.4 0.0 0.22 11.0 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EMC87984.1 - 0.0064 15.3 2.3 2.5 6.7 0.0 4.4 5 0 0 5 5 5 2 Coatomer WD associated region Gmad1 PF10647.4 EMC87984.1 - 0.013 14.9 0.0 23 4.2 0.0 4.7 5 0 0 5 5 5 0 Lipoprotein LpqB beta-propeller domain zf-CCCH_2 PF14608.1 EMC87985.1 - 1.7e-16 59.4 57.7 6.4e-07 29.1 3.9 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Y_phosphatase PF00102.22 EMC87986.1 - 2.1e-73 246.5 0.0 3.5e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.13 EMC87986.1 - 7.5e-20 71.3 1.4 2.2e-19 69.8 1.0 1.8 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 EMC87986.1 - 1.8e-17 63.1 0.3 1.8e-17 63.1 0.2 2.4 3 0 0 3 3 3 1 FERM N-terminal domain FERM_C PF09380.5 EMC87986.1 - 4.4e-17 62.0 0.2 9.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.15 EMC87986.1 - 2.5e-05 23.8 0.0 5.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC87986.1 - 0.0024 18.1 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family HSD3 PF15244.1 EMC87987.1 - 1.5e-31 110.0 2.1 2.3e-31 109.5 1.5 1.1 1 0 0 1 1 1 1 Hydroxy-steroid dehydrogenase CARD PF00619.16 EMC87987.1 - 0.0055 16.5 0.6 0.011 15.5 0.4 1.5 1 0 0 1 1 1 1 Caspase recruitment domain PUF PF00806.14 EMC87987.1 - 0.069 12.6 0.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat DUF3767 PF12597.3 EMC87987.1 - 0.12 12.0 0.4 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Ion_trans_2 PF07885.11 EMC87988.1 - 1.1e-36 124.3 23.1 4.3e-19 68.0 0.5 3.2 3 1 1 4 4 4 3 Ion channel OST3_OST6 PF04756.8 EMC87988.1 - 0.00037 20.1 2.9 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family 7tm_1 PF00001.16 EMC87988.1 - 0.027 13.6 1.6 0.031 13.4 0.3 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.7 EMC87988.1 - 0.41 10.6 5.0 3.2 7.7 0.6 2.9 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.16 EMC87989.1 - 2.1e-48 164.7 20.0 3.1e-48 164.1 13.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC87989.1 - 0.0028 16.8 16.6 0.004 16.3 11.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Str PF10326.4 EMC87989.1 - 0.035 13.2 19.8 61 2.5 13.7 2.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Glyco_hydro_59 PF02057.10 EMC87990.1 - 0 1120.5 4.8 0 1120.3 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Laminin_G_3 PF13385.1 EMC87990.1 - 0.0021 18.3 6.0 0.0028 17.8 2.3 2.5 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily LRR_8 PF13855.1 EMC87991.1 - 3e-33 113.3 26.0 2.1e-12 46.5 3.4 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EMC87991.1 - 6.4e-26 89.4 29.6 1.9e-06 27.3 1.4 7.4 4 3 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC87991.1 - 2e-17 60.5 21.1 0.079 13.0 0.1 11.7 10 1 1 11 11 11 2 Leucine Rich Repeat LRR_5 PF13306.1 EMC87991.1 - 6.7e-10 38.7 0.0 3.1e-06 26.9 0.0 3.4 2 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC87991.1 - 1.2e-06 27.7 25.3 5.7 7.6 0.1 11.1 11 0 0 11 11 11 1 Leucine rich repeat LRR_9 PF14580.1 EMC87991.1 - 2.6e-05 23.8 7.8 0.079 12.5 0.1 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 EMC87991.1 - 0.00011 21.9 24.1 5.9 7.2 0.0 8.8 7 3 2 9 9 9 2 Leucine Rich repeat LRRNT PF01462.13 EMC87991.1 - 0.00014 21.2 2.1 0.00014 21.2 1.5 3.8 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain fn3 PF00041.16 EMC87991.1 - 0.00089 19.3 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 EMC87991.1 - 0.0013 18.8 0.1 0.0045 17.1 0.1 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain MLANA PF14991.1 EMC87991.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A HemY_N PF07219.8 EMC87991.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Herpes_LMP1 PF05297.6 EMC87993.1 - 0.02 13.8 23.4 2.3 7.0 1.2 4.5 1 1 4 5 5 5 0 Herpesvirus latent membrane protein 1 (LMP1) DEADboxA PF12343.3 EMC87993.1 - 5.5 7.3 177.5 6.2 7.1 10.4 8.7 1 1 7 8 8 8 0 Cold shock protein DEAD box A Homeobox PF00046.24 EMC87994.1 - 8.1e-20 70.1 0.4 1.6e-19 69.2 0.3 1.5 1 0 0 1 1 1 1 Homeobox domain Pou PF00157.12 EMC87994.1 - 1.1e-17 63.4 0.5 2.4e-17 62.3 0.4 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox_KN PF05920.6 EMC87994.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 EMC87994.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MIP-T3 PF10243.4 EMC87995.1 - 0.00066 18.2 83.6 0.00078 18.0 58.0 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CENP-T PF15511.1 EMC87995.1 - 0.45 9.6 27.7 0.47 9.6 19.2 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EMC87995.1 - 0.71 7.7 57.5 0.89 7.4 39.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EMC87995.1 - 2.3 7.4 61.8 3.9 6.6 42.8 1.3 1 0 0 1 1 1 0 SDA1 Claudin_2 PF13903.1 EMC87996.1 - 2.3e-32 112.0 5.6 3.2e-32 111.5 3.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.4 EMC87996.1 - 0.014 13.9 1.3 0.022 13.3 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MnhB PF04039.8 EMC87996.1 - 7.1 6.7 14.1 2.5 8.1 0.5 2.4 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter MFS_1 PF07690.11 EMC87997.1 - 1.9e-39 135.3 22.6 2.4e-39 135.0 15.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC87997.1 - 2.7e-08 32.8 7.4 2.7e-08 32.8 5.2 2.8 1 1 0 3 3 3 2 Sugar (and other) transporter Na_H_Exchanger PF00999.16 EMC87998.1 - 9.7e-80 267.9 35.7 1.1e-79 267.6 24.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TIR PF01582.15 EMC87999.1 - 3.4e-32 110.7 0.1 1.2e-31 108.9 0.0 2.0 2 0 0 2 2 2 1 TIR domain Ig_2 PF13895.1 EMC87999.1 - 4.1e-14 52.4 1.9 2.3e-05 24.4 0.8 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 EMC87999.1 - 5.1e-09 35.8 4.6 0.0012 18.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain TIR_2 PF13676.1 EMC87999.1 - 2.7e-06 27.4 0.0 6.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain ig PF00047.20 EMC87999.1 - 5.7e-05 23.1 1.0 0.3 11.2 0.1 3.9 4 0 0 4 4 4 1 Immunoglobulin domain Ig_3 PF13927.1 EMC87999.1 - 7.5e-05 23.1 0.3 0.11 13.0 0.0 4.1 2 1 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.10 EMC87999.1 - 0.0061 16.5 0.2 1.1 9.3 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin C1-set domain V-set PF07686.12 EMC87999.1 - 0.0079 16.0 7.4 6.8 6.6 2.7 3.9 2 1 1 3 3 3 2 Immunoglobulin V-set domain DUF2180 PF09947.4 EMC87999.1 - 0.061 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) TIR PF01582.15 EMC88000.1 - 4.5e-33 113.6 0.6 7.1e-33 113.0 0.4 1.3 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 EMC88000.1 - 1.5e-19 69.8 0.4 8.6e-06 25.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC88000.1 - 8.2e-15 55.0 2.2 8.5e-05 22.9 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.11 EMC88000.1 - 3.6e-14 52.3 1.2 2.2e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 EMC88000.1 - 7.6e-12 45.1 5.2 0.00016 21.7 0.1 4.0 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 EMC88000.1 - 1.9e-11 43.8 2.0 0.00067 19.5 0.1 3.9 2 1 0 3 3 3 3 Immunoglobulin V-set domain V-set_CD47 PF08204.6 EMC88000.1 - 0.0002 21.1 0.2 0.098 12.4 0.0 3.2 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain TIR_2 PF13676.1 EMC88000.1 - 0.0079 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain BiPBP_C PF06832.7 EMC88000.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.7 EMC88000.1 - 0.021 14.6 0.0 1.9 8.4 0.0 3.2 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain TIR PF01582.15 EMC88001.1 - 3.9e-32 110.6 0.0 6.4e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain I-set PF07679.11 EMC88001.1 - 2.3e-16 59.3 3.1 0.00016 21.4 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC88001.1 - 6.9e-16 58.1 2.7 1.1e-05 25.4 0.2 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC88001.1 - 6.7e-08 32.9 8.1 0.25 11.8 0.5 4.4 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC88001.1 - 5.7e-06 26.3 3.2 0.11 12.6 0.1 3.9 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 EMC88001.1 - 0.00015 21.6 11.1 0.17 11.7 0.6 4.8 2 2 1 3 3 3 2 Immunoglobulin V-set domain Lep_receptor_Ig PF06328.6 EMC88001.1 - 0.033 14.0 0.9 0.28 11.0 0.0 2.9 3 1 1 4 4 4 0 Ig-like C2-type domain TIR PF01582.15 EMC88002.1 - 4.7e-35 120.0 0.3 1.5e-34 118.4 0.1 2.0 2 0 0 2 2 2 1 TIR domain Ig_2 PF13895.1 EMC88002.1 - 4.7e-16 58.6 1.2 1.4e-06 28.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 EMC88002.1 - 8.1e-16 57.6 0.0 9.5e-06 25.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC88002.1 - 2.1e-07 31.3 1.1 0.96 10.0 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 EMC88002.1 - 3.6e-07 30.2 1.3 0.0043 17.1 0.0 4.0 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 EMC88002.1 - 0.00044 20.1 5.8 0.94 9.3 0.5 4.4 3 3 0 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC88003.1 - 2.8e-17 62.6 0.2 5.6e-06 26.3 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC88003.1 - 1.4e-13 50.7 2.1 0.00024 21.1 0.0 4.8 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.11 EMC88003.1 - 3.7e-13 49.1 0.0 0.00012 21.8 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC88003.1 - 2.9e-10 40.4 2.2 0.046 14.2 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC88003.1 - 2.3e-07 30.6 1.8 0.0099 15.7 0.1 3.9 3 2 0 3 3 3 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 EMC88003.1 - 0.039 12.2 0.0 0.21 9.8 0.0 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E CNH PF00780.17 EMC88004.1 - 8.8e-60 202.4 0.0 1.5e-59 201.7 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 EMC88004.1 - 1e-53 182.1 0.0 1e-53 182.1 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88004.1 - 2.2e-38 131.8 0.0 5.2e-38 130.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase FBD PF08387.5 EMC88005.1 - 0.065 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 FBD Pyrid_oxidase_2 PF13883.1 EMC88006.1 - 1.1e-40 139.1 0.0 1.2e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EMC88006.1 - 0.027 14.4 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-RING_2 PF13639.1 EMC88007.1 - 1.1e-14 53.9 7.3 1.8e-14 53.2 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EMC88007.1 - 4.7e-10 39.0 0.1 9.3e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EMC88007.1 - 9e-10 38.5 4.2 1.8e-09 37.5 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC88007.1 - 4.4e-08 32.6 6.9 7.2e-08 31.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC88007.1 - 4.7e-07 29.7 7.8 8.3e-07 28.9 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC88007.1 - 4.9e-07 29.3 5.1 7.6e-07 28.7 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC88007.1 - 8.4e-07 28.5 4.4 1.4e-06 27.8 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0233 PF06781.7 EMC88007.1 - 0.007 15.9 1.6 0.012 15.1 0.7 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0233) zf-Apc11 PF12861.2 EMC88007.1 - 0.027 14.3 4.3 0.055 13.3 3.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EMC88007.1 - 0.028 14.1 3.5 0.061 13.0 2.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PspB PF06667.7 EMC88007.1 - 0.13 12.1 0.7 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Phage shock protein B Prok-RING_1 PF14446.1 EMC88007.1 - 0.17 11.6 5.7 0.094 12.4 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 EMC88007.1 - 0.53 9.8 4.8 0.48 10.0 2.3 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.24 EMC88007.1 - 1.3 8.8 4.8 2.8 7.7 3.3 1.6 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EMC88007.1 - 2.8 8.0 6.1 5.6 7.0 4.2 1.5 1 0 0 1 1 1 0 RING-variant domain DUF2363 PF10155.4 EMC88008.1 - 5.4e-54 181.4 6.6 7.6e-54 180.9 4.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) RabGAP-TBC PF00566.13 EMC88009.1 - 2.7e-46 157.7 0.0 6.2e-46 156.5 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EMC88009.1 - 3.1e-33 113.1 1.6 4e-16 58.2 0.1 2.5 2 0 0 2 2 2 2 GRAM domain Ribosomal_L31e PF01198.14 EMC88010.1 - 2.3e-40 136.1 2.8 3.3e-40 135.6 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.10 EMC88010.1 - 0.056 13.0 0.1 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 DNA mismatch endonuclease Vsr Phosducin PF02114.11 EMC88012.1 - 1.7e-17 63.0 1.8 1.9e-17 62.8 0.9 1.3 1 1 0 1 1 1 1 Phosducin GOLD_2 PF13897.1 EMC88012.1 - 0.33 11.1 2.6 0.29 11.3 0.8 1.7 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF3210 PF11489.3 EMC88012.1 - 0.57 8.8 3.2 0.77 8.3 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) Histone PF00125.19 EMC88013.1 - 8.5e-24 83.4 0.0 1.1e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC88013.1 - 1.4e-05 25.0 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ACT_4 PF13291.1 EMC88013.1 - 0.13 12.6 0.0 4.7 7.6 0.0 2.1 2 0 0 2 2 2 0 ACT domain Histone PF00125.19 EMC88014.1 - 5.5e-22 77.6 0.1 9.1e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC88014.1 - 6.4e-05 22.9 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EMC88014.1 - 0.0031 17.4 0.1 0.0048 16.8 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) tRNA-synt_1f PF01921.13 EMC88014.1 - 0.1 11.2 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) Sulfotransfer_2 PF03567.9 EMC88016.1 - 9.5e-52 176.1 0.1 1.2e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family LON PF02190.11 EMC88017.1 - 2.7e-25 89.2 0.0 5.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EMC88017.1 - 4.3e-09 36.2 15.2 9.7e-09 35.1 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC88017.1 - 6.6e-09 35.3 9.8 1.5e-08 34.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC88017.1 - 2.6e-08 33.5 15.4 6.5e-08 32.2 10.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMC88017.1 - 5.4e-07 29.1 14.7 1.3e-06 27.9 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC88017.1 - 4e-06 26.4 13.7 8.3e-06 25.4 9.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_2 PF07719.12 EMC88017.1 - 4.6e-05 23.0 0.8 0.066 13.1 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 EMC88017.1 - 5.3e-05 23.0 14.4 5.3e-05 23.0 10.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC88017.1 - 0.00032 20.3 7.4 0.00054 19.6 2.9 2.8 2 1 1 3 3 3 1 RING-type zinc-finger TPR_11 PF13414.1 EMC88017.1 - 0.00054 19.5 0.8 0.0062 16.1 0.2 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMC88017.1 - 0.00061 19.2 2.7 6.4 6.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat U-box PF04564.10 EMC88017.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 EMC88017.1 - 0.0083 16.2 6.0 0.021 14.9 4.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EMC88017.1 - 0.012 15.1 9.7 0.035 13.7 6.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_9 PF13371.1 EMC88017.1 - 0.02 14.7 0.2 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 EMC88017.1 - 0.029 14.1 6.1 0.07 12.9 4.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AF-4 PF05110.8 EMC88018.1 - 4.4e-76 256.7 19.1 1.1e-55 189.2 3.0 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein IMS PF00817.15 EMC88020.1 - 2.4e-42 144.2 0.0 4.3e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMC88020.1 - 1.4e-19 70.2 0.0 3.9e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EMC88020.1 - 4.5e-08 33.1 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 EMC88020.1 - 6.7e-07 29.1 5.1 0.0038 17.1 0.3 3.4 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EMC88020.1 - 1.3e-05 24.9 0.0 0.0011 18.8 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 EMC88020.1 - 5.5e-05 22.9 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 EMC88020.1 - 0.0023 18.0 0.0 0.0089 16.1 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 EMC88020.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.6 EMC88020.1 - 0.13 12.0 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) GTP_EFTU PF00009.22 EMC88021.1 - 1.1e-32 113.0 0.3 1.1e-32 113.0 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMC88021.1 - 1.1e-18 67.0 0.1 4.6e-18 65.1 0.0 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMC88021.1 - 5.2e-10 39.2 4.6 6e-07 29.4 0.2 3.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EMC88021.1 - 4.7e-08 32.5 0.8 1.3e-07 31.1 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Sec23_helical PF04815.10 EMC88021.1 - 0.097 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Thioredoxin PF00085.15 EMC88022.1 - 3.4e-10 39.5 0.1 7.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EMC88022.1 - 1.3e-09 37.2 0.6 1.7e-09 36.7 0.4 1.1 1 0 0 1 1 1 1 Phosducin TPK_B1_binding PF04265.9 EMC88022.1 - 0.2 11.4 0.5 1.2 8.8 0.0 2.3 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF342 PF03961.8 EMC88022.1 - 1.1 7.5 6.2 1.3 7.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BAG PF02179.11 EMC88022.1 - 4.6 7.4 9.4 1.3 9.1 4.1 1.9 2 0 0 2 2 2 0 BAG domain SLT PF01464.15 EMC88023.1 - 1.8e-08 33.9 0.0 2.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Melibiase PF02065.13 EMC88023.1 - 0.016 13.9 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 Melibiase SLT PF01464.15 EMC88024.1 - 1.9e-18 66.1 0.1 2.4e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Toxin_16 PF07945.6 EMC88024.1 - 0.0044 16.6 0.6 0.01 15.5 0.4 1.5 1 0 0 1 1 1 1 Janus-atracotoxin SLT PF01464.15 EMC88025.1 - 1.9e-14 53.2 0.0 2.4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.1 EMC88025.1 - 0.05 12.5 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain Ribosomal_L30 PF00327.15 EMC88026.1 - 5.9e-11 41.7 1.0 8.7e-11 41.2 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e VWD PF00094.20 EMC88027.1 - 9.9e-80 266.3 25.0 1.5e-30 106.4 2.3 4.9 4 1 0 4 4 4 3 von Willebrand factor type D domain C8 PF08742.6 EMC88027.1 - 2.6e-56 187.7 47.1 4.6e-22 78.0 10.7 7.2 7 2 1 8 8 8 3 C8 domain TIL PF01826.12 EMC88027.1 - 3.4e-20 71.9 54.8 2.2e-11 43.6 10.4 11.4 9 3 1 10 10 10 4 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 EMC88027.1 - 8.1e-06 25.8 25.0 0.00025 21.0 5.6 11.6 6 5 2 8 8 8 2 von Willebrand factor type C domain CUE PF02845.11 EMC88028.1 - 5.5e-16 57.7 0.2 1.1e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 CUE domain C2 PF00168.25 EMC88028.1 - 8.3e-10 38.3 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain UBA PF00627.26 EMC88028.1 - 0.0046 16.7 0.1 0.0094 15.7 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.14 EMC88028.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Pkinase PF00069.20 EMC88029.1 - 1.2e-62 211.4 0.0 1.7e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88029.1 - 9.6e-33 113.3 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC88029.1 - 9.9e-05 22.1 0.0 0.002 17.8 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC88029.1 - 0.0023 17.5 0.3 0.0067 16.0 0.2 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EMC88029.1 - 0.003 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC88029.1 - 0.03 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.12 EMC88030.1 - 2.9e-59 199.6 4.9 3.7e-59 199.3 3.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family DSPc PF00782.15 EMC88031.1 - 6.1e-44 148.8 0.0 9.3e-44 148.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EMC88031.1 - 1.2e-11 44.9 0.0 2e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 EMC88031.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC88031.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Dispanin PF04505.7 EMC88032.1 - 1.4e-21 75.7 0.1 1.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein ScdA_N PF04405.9 EMC88032.1 - 0.034 13.5 0.5 0.17 11.2 0.1 2.1 1 1 1 2 2 2 0 Domain of Unknown function (DUF542) Asp PF00026.18 EMC88033.1 - 5.5e-128 426.6 0.0 6.3e-128 426.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC88033.1 - 1.1e-09 38.4 0.0 1.4e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 EMC88033.1 - 1e-07 31.4 0.0 1e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 A1 Propeptide TAXi_C PF14541.1 EMC88033.1 - 4.6e-06 26.2 0.0 1.9e-05 24.2 0.0 2.0 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EMC88033.1 - 7.3e-05 23.1 0.2 0.2 12.1 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease 5-nucleotidase PF06189.7 EMC88034.1 - 3e-85 285.2 0.0 1.3e-84 283.1 0.0 1.7 1 1 1 2 2 2 2 5'-nucleotidase C2 PF00168.25 EMC88036.1 - 4.7e-50 167.3 4.8 3.2e-25 87.7 0.1 2.2 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 EMC88036.1 - 1.7e-06 27.7 0.5 0.00017 21.2 0.0 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 EMC88036.1 - 0.00026 20.5 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 2 CEP76 C2 domain Adeno_E3_CR2 PF02439.10 EMC88036.1 - 0.0052 16.3 2.2 0.01 15.3 1.6 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Shisa PF13908.1 EMC88036.1 - 0.0091 16.1 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 EMC88036.1 - 0.02 14.5 0.8 0.086 12.5 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family SIT PF15330.1 EMC88036.1 - 0.026 14.6 0.1 0.049 13.7 0.1 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT LRRC37AB_C PF14914.1 EMC88036.1 - 0.044 13.2 0.3 0.11 11.9 0.2 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Tweety PF04906.8 EMC88036.1 - 0.066 11.6 1.3 0.12 10.7 0.9 1.3 1 0 0 1 1 1 0 Tweety Rhabdo_glycop PF00974.13 EMC88036.1 - 0.098 10.8 0.5 0.16 10.2 0.4 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein EphA2_TM PF14575.1 EMC88036.1 - 0.11 12.8 0.7 0.31 11.4 0.5 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 EMC88036.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 IncA protein Troponin PF00992.15 EMC88037.1 - 1.5e-52 177.1 8.8 1.5e-52 177.1 6.1 1.4 2 0 0 2 2 2 1 Troponin DUF919 PF06034.6 EMC88037.1 - 0.0058 16.2 1.6 0.0058 16.2 1.1 2.7 2 1 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF919) His_Phos_2 PF00328.17 EMC88037.1 - 0.099 11.9 3.2 0.17 11.1 0.1 2.0 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Erp_C PF06780.6 EMC88037.1 - 0.12 12.2 9.3 1 9.2 1.4 2.3 2 0 0 2 2 2 0 Erp protein C-terminus Laminin_II PF06009.7 EMC88037.1 - 0.14 11.9 2.6 0.28 10.9 1.0 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF2408 PF10303.4 EMC88037.1 - 0.17 11.9 5.2 0.44 10.6 3.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CENP-F_leu_zip PF10473.4 EMC88037.1 - 1.3 8.8 16.2 0.11 12.4 5.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 EMC88037.1 - 3.9 5.1 5.2 2.2 6.0 2.3 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Microtub_bind PF13931.1 EMC88037.1 - 4.5 7.4 7.9 2.7 8.1 1.7 2.1 1 1 0 2 2 2 0 Kinesin-associated microtubule-binding Tropomyosin_1 PF12718.2 EMC88037.1 - 4.8 7.0 19.5 0.29 10.9 1.3 3.1 3 0 0 3 3 3 0 Tropomyosin like TMPIT PF07851.8 EMC88037.1 - 6 5.8 5.6 24 3.8 1.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein Caldesmon PF02029.10 EMC88038.1 - 6.8e-30 103.9 65.4 2.6e-14 52.5 0.4 4.1 2 2 1 3 3 3 3 Caldesmon Recep_L_domain PF01030.19 EMC88038.1 - 0.076 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Receptor L domain LMBR1 PF04791.11 EMC88038.1 - 7.3 5.0 6.3 9.1 4.7 4.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4643 PF15485.1 EMC88039.1 - 5.3e-60 203.3 15.0 5.3e-60 203.3 10.4 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4643) Troponin PF00992.15 EMC88041.1 - 6.9e-38 129.6 42.2 1.7e-36 125.1 24.4 2.1 2 0 0 2 2 2 2 Troponin Peptidase_S64 PF08192.6 EMC88041.1 - 0.093 11.0 8.1 0.11 10.8 5.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_L23 PF00276.15 EMC88042.1 - 1.6e-13 50.4 1.0 2.4e-13 49.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpc4 PF05132.9 EMC88042.1 - 0.19 11.7 0.9 0.25 11.3 0.2 1.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Insulin PF00049.13 EMC88046.1 - 3.4e-14 53.3 5.5 1.4e-06 28.9 1.6 2.4 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family IGF2_C PF08365.6 EMC88046.1 - 1.6e-06 27.7 4.3 3.2e-06 26.7 3.0 1.6 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Ins_beta PF03488.9 EMC88046.1 - 0.46 10.3 4.7 5.5 6.8 0.1 2.4 2 1 0 2 2 2 0 Nematode insulin-related peptide beta type Insulin PF00049.13 EMC88047.1 - 2.7e-24 85.7 1.0 3.5e-24 85.4 0.7 1.1 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.9 EMC88047.1 - 0.019 14.7 4.7 0.61 9.9 0.1 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type TRM13 PF05206.9 EMC88047.1 - 0.057 12.6 0.4 0.21 10.8 0.3 1.7 1 1 0 1 1 1 0 Methyltransferase TRM13 Biopterin_H PF00351.16 EMC88048.1 - 6.3e-195 646.4 0.7 8e-195 646.0 0.5 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TOH_N PF12549.3 EMC88048.1 - 4.4e-17 60.9 9.2 1.5e-11 43.3 0.5 3.1 3 0 0 3 3 3 2 Tyrosine hydroxylase N terminal DUF4559 PF15112.1 EMC88048.1 - 0.046 12.8 0.1 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tetraspannin PF00335.15 EMC88049.1 - 8.4e-20 70.9 10.4 1e-19 70.7 7.2 1.0 1 0 0 1 1 1 1 Tetraspanin family ABC2_membrane_2 PF12679.2 EMC88049.1 - 1.2 7.8 9.6 2.7 6.7 6.5 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Tetraspannin PF00335.15 EMC88050.1 - 1.3e-39 135.7 11.6 1.5e-39 135.5 8.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Cad PF03596.8 EMC88050.1 - 0.089 12.4 0.2 0.089 12.4 0.2 1.9 2 0 0 2 2 2 0 Cadmium resistance transporter Claudin_2 PF13903.1 EMC88050.1 - 0.09 12.4 5.2 0.17 11.5 1.2 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TSSC4 PF15264.1 EMC88051.1 - 3.5e-29 101.6 0.7 6.5e-29 100.7 0.0 1.8 2 0 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 Ion_trans PF00520.26 EMC88052.1 - 0.00015 21.1 24.9 0.00015 21.1 17.3 2.7 2 1 0 2 2 2 1 Ion transport protein Mso1_Sec1_bdg PF14475.1 EMC88052.1 - 0.039 13.3 0.1 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Ion_trans PF00520.26 EMC88053.1 - 1.7e-24 86.2 8.0 1.7e-24 86.2 5.5 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EMC88053.1 - 1.2e-11 44.0 7.0 1.2e-11 44.0 4.9 2.5 2 0 0 2 2 2 1 Ion channel Dispanin PF04505.7 EMC88053.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.4 3 0 0 3 3 3 0 Interferon-induced transmembrane protein MFS_1 PF07690.11 EMC88054.1 - 1.5e-32 112.7 71.9 5.5e-26 91.1 31.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EMC88054.1 - 5.6e-05 21.4 16.1 0.015 13.4 2.0 3.6 2 2 2 4 4 4 3 Transmembrane secretion effector PH PF00169.24 EMC88055.1 - 2.9e-06 27.4 0.1 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 PH domain NAP PF00956.13 EMC88056.1 - 5.6e-93 310.5 4.8 5.6e-93 310.5 3.3 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) tRNA-synt_1e PF01406.14 EMC88057.1 - 4.6e-128 426.5 0.1 4.6e-128 426.5 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EMC88057.1 - 3.4e-08 32.5 0.3 0.00011 20.9 0.1 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMC88057.1 - 0.00081 17.5 2.4 0.0016 16.4 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) GST_C_3 PF14497.1 EMC88057.1 - 0.027 14.9 1.6 0.18 12.2 0.0 3.3 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain TNFR_c6 PF00020.13 EMC88058.1 - 1.2e-07 31.6 4.4 1.2e-07 31.6 3.1 3.0 2 1 1 3 3 3 2 TNFR/NGFR cysteine-rich region hEGF PF12661.2 EMC88058.1 - 0.13 12.3 1.4 0.13 12.3 1.0 3.2 4 0 0 4 4 4 0 Human growth factor-like EGF Y_phosphatase PF00102.22 EMC88059.1 - 5.7e-87 290.9 1.0 1.1e-86 290.0 0.7 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.16 EMC88059.1 - 1e-50 169.7 22.2 3e-08 33.6 0.3 7.4 7 0 0 7 7 7 6 Fibronectin type III domain GPI-anchored PF10342.4 EMC88059.1 - 2.9e-05 24.4 25.5 0.51 10.8 0.5 6.7 3 2 5 8 8 8 3 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PTPlike_phytase PF14566.1 EMC88059.1 - 0.0013 18.7 0.0 0.0037 17.3 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF2136 PF09907.4 EMC88059.1 - 0.0031 17.5 0.1 21 5.2 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2136) Y_phosphatase3 PF13350.1 EMC88059.1 - 0.0041 17.3 0.0 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EMC88059.1 - 0.0053 16.3 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 EMC88059.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Syndecan PF01034.15 EMC88059.1 - 0.081 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain Y_phosphatase PF00102.22 EMC88060.1 - 2.3e-75 252.9 0.9 4.5e-75 251.9 0.6 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC88060.1 - 6e-07 29.1 0.0 1.9e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC88060.1 - 0.00066 19.9 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC88060.1 - 0.03 14.3 0.0 0.099 12.6 0.0 1.8 1 1 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 EMC88060.1 - 0.058 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3910 PF13049.1 EMC88060.1 - 0.09 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) CPSase_L_D2 PF02786.12 EMC88060.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF307 PF03733.8 EMC88060.1 - 0.15 12.5 1.1 0.44 11.0 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF307) I-set PF07679.11 EMC88061.1 - 0.00019 21.2 0.1 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain YhhN PF07947.9 EMC88062.1 - 3.8e-45 153.5 24.1 3.8e-45 153.5 16.7 1.3 2 0 0 2 2 2 1 YhhN-like protein YtpI PF14007.1 EMC88062.1 - 3.4 7.6 8.8 0.44 10.4 0.4 3.0 2 1 1 3 3 3 0 YtpI-like protein UEV PF05743.8 EMC88063.1 - 2.6e-42 143.3 0.1 4.2e-42 142.6 0.1 1.3 1 0 0 1 1 1 1 UEV domain Ldh_1_N PF00056.18 EMC88063.1 - 6.2e-23 81.1 0.4 1e-22 80.4 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMC88063.1 - 1.3e-13 51.0 0.0 3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.12 EMC88063.1 - 0.014 15.8 1.0 0.047 14.1 0.2 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 EMC88063.1 - 0.11 11.3 0.1 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UEV PF05743.8 EMC88064.1 - 2.4e-47 159.5 1.3 2.4e-46 156.3 0.2 2.2 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 EMC88064.1 - 1.3e-28 98.4 0.2 2.3e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EMC88064.1 - 0.00036 19.9 0.4 0.00036 19.9 0.3 2.0 2 0 0 2 2 1 1 Ubiquitin-conjugating enzyme APG6 PF04111.7 EMC88064.1 - 0.0027 16.8 7.4 0.0039 16.2 5.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3450 PF11932.3 EMC88064.1 - 0.0054 16.0 6.7 0.0054 16.0 4.7 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Macoilin PF09726.4 EMC88064.1 - 0.0088 14.3 3.8 0.012 13.9 2.6 1.1 1 0 0 1 1 1 1 Transmembrane protein V_ATPase_I PF01496.14 EMC88064.1 - 0.024 12.5 2.4 0.031 12.1 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMC88064.1 - 0.027 14.0 6.6 0.039 13.5 4.5 1.3 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 EMC88064.1 - 0.027 12.3 1.3 0.034 12.0 0.9 1.1 1 0 0 1 1 1 0 Hsp70 protein SlyX PF04102.7 EMC88064.1 - 0.032 14.6 3.9 0.032 14.6 2.7 2.9 2 1 1 3 3 3 0 SlyX LXG PF04740.7 EMC88064.1 - 0.038 13.7 3.4 0.07 12.9 2.4 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF1640 PF07798.6 EMC88064.1 - 0.048 13.7 8.5 0.048 13.7 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) TBPIP PF07106.8 EMC88064.1 - 0.049 13.1 7.8 0.078 12.5 5.4 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EMC88064.1 - 0.058 11.7 4.9 0.081 11.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EMC88064.1 - 0.11 12.2 13.0 0.28 10.8 4.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF848 PF05852.6 EMC88064.1 - 0.12 12.2 4.5 0.22 11.3 3.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2317 PF10079.4 EMC88064.1 - 0.16 10.5 4.9 0.24 9.9 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Reo_sigmaC PF04582.7 EMC88064.1 - 0.17 11.0 0.3 0.26 10.4 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Nup88 PF10168.4 EMC88064.1 - 0.18 9.6 3.8 0.26 9.0 2.6 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF1002 PF06207.6 EMC88064.1 - 0.19 11.0 5.7 0.3 10.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Fzo_mitofusin PF04799.8 EMC88064.1 - 0.2 11.0 4.3 0.36 10.1 3.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region Nsp1_C PF05064.8 EMC88064.1 - 0.24 11.0 7.8 0.21 11.2 3.8 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region FlxA PF14282.1 EMC88064.1 - 0.36 10.7 4.6 0.63 10.0 3.2 1.3 1 0 0 1 1 1 0 FlxA-like protein Bap31 PF05529.7 EMC88064.1 - 0.39 10.1 5.6 0.66 9.4 3.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF641 PF04859.7 EMC88064.1 - 0.55 9.9 5.8 1.1 9.0 4.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF724 PF05266.9 EMC88064.1 - 0.86 9.1 8.6 1.4 8.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.17 EMC88064.1 - 0.86 9.6 10.8 0.76 9.8 5.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3552 PF12072.3 EMC88064.1 - 0.87 8.7 12.1 1.4 8.1 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) NPV_P10 PF05531.7 EMC88064.1 - 1.3 9.3 5.7 3.4 7.9 2.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 EMC88064.1 - 3.3 7.3 10.5 2.7 7.6 1.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF4164 PF13747.1 EMC88064.1 - 4.1 7.6 12.1 2.6 8.2 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.15 EMC88064.1 - 4.5 7.0 15.1 4.2 7.1 2.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 EMC88064.1 - 6.4 6.2 13.0 0.37 10.2 1.3 2.7 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF972 PF06156.8 EMC88064.1 - 9.6 6.6 9.5 26 5.2 6.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) BSD PF03909.12 EMC88065.1 - 5.6e-29 99.6 0.8 3e-15 55.7 0.0 3.0 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EMC88065.1 - 8.8e-22 76.5 0.0 1.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF2652 PF10851.3 EMC88065.1 - 0.039 13.9 0.2 8 6.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2652) HNF-1_N PF04814.8 EMC88065.1 - 0.1 12.7 1.7 14 5.7 0.2 2.5 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SAA PF00277.13 EMC88067.1 - 9.6e-44 147.9 6.7 1.2e-43 147.6 4.7 1.1 1 0 0 1 1 1 1 Serum amyloid A protein Golgin_A5 PF09787.4 EMC88068.1 - 0.0084 14.6 0.6 0.01 14.4 0.4 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 SCRG1 PF15224.1 EMC88068.1 - 0.028 14.2 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 Scrapie-responsive protein 1 IKKbetaNEMObind PF12179.3 EMC88068.1 - 0.18 11.6 2.3 0.23 11.3 0.5 2.0 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Biopterin_H PF00351.16 EMC88069.1 - 3.7e-189 627.4 0.1 4.8e-189 627.1 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EMC88069.1 - 2.8e-07 29.8 0.0 6.7e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EMC88069.1 - 0.31 11.4 2.4 0.24 11.7 0.2 1.9 2 0 0 2 2 2 0 ACT domain RCC1 PF00415.13 EMC88070.1 - 4.1e-55 183.7 16.5 5.6e-10 39.2 0.1 7.4 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMC88070.1 - 5e-31 105.6 41.7 1.9e-08 33.7 1.2 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Ion_trans PF00520.26 EMC88071.1 - 1.5e-32 112.4 8.3 1.5e-32 112.4 5.7 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC88071.1 - 1.8e-28 98.6 0.0 4.3e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC88071.1 - 8.9e-11 41.3 2.9 8.9e-11 41.3 2.0 2.5 2 0 0 2 2 2 1 Ion channel DUF202 PF02656.10 EMC88071.1 - 0.66 10.2 4.4 1.3e+02 2.9 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PKD_channel PF08016.7 EMC88071.1 - 5.2 5.3 9.2 1.1 7.6 2.4 2.0 1 1 1 2 2 2 0 Polycystin cation channel VWD PF00094.20 EMC88073.1 - 5.6e-75 250.8 8.8 1.6e-34 119.3 0.1 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.6 EMC88073.1 - 1.2e-50 169.6 54.7 1.3e-19 70.1 8.8 9.0 8 1 1 9 9 9 4 C8 domain AbfB PF05270.8 EMC88073.1 - 3.8e-18 65.5 0.1 8.6e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) TIL PF01826.12 EMC88073.1 - 5.3e-13 48.8 77.8 3.9e-10 39.7 13.7 17.1 15 4 4 19 19 19 5 Trypsin Inhibitor like cysteine rich domain ABC_membrane PF00664.18 EMC88074.1 - 2.6e-72 243.5 31.1 4.4e-38 131.2 3.9 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC88074.1 - 3.4e-50 169.9 2.3 1.8e-24 86.5 0.0 3.7 4 0 0 4 4 4 2 ABC transporter SMC_N PF02463.14 EMC88074.1 - 1e-10 41.2 2.1 0.00077 18.7 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMC88074.1 - 7.1e-08 32.7 2.0 0.56 10.1 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_25 PF13481.1 EMC88074.1 - 2e-07 30.6 0.0 0.00093 18.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EMC88074.1 - 7.5e-05 21.4 1.0 0.027 13.0 0.0 3.1 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 EMC88074.1 - 0.00015 21.2 0.2 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EMC88074.1 - 0.0003 21.2 0.1 1.1 9.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EMC88074.1 - 0.0012 18.0 0.1 0.043 13.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 EMC88074.1 - 0.0032 16.3 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EMC88074.1 - 0.0044 16.9 0.0 0.64 9.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMC88074.1 - 0.005 16.8 0.0 0.049 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.20 EMC88074.1 - 0.0064 16.0 0.1 0.3 10.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EMC88074.1 - 0.0074 15.4 0.1 0.22 10.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EMC88074.1 - 0.017 14.5 0.4 2.2 7.6 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EMC88074.1 - 0.025 14.7 0.1 11 6.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EMC88074.1 - 0.043 12.9 0.3 7.1 5.6 0.0 2.5 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.13 EMC88074.1 - 0.069 12.6 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF688 PF05097.7 EMC88074.1 - 0.2 10.5 0.1 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) AAA_23 PF13476.1 EMC88074.1 - 0.37 11.0 11.1 16 5.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMC88074.1 - 7.5 6.3 8.9 0.65 9.8 0.1 3.0 3 0 0 3 3 3 0 Dynamin family IRK PF01007.15 EMC88075.1 - 1.6e-151 503.8 0.0 2e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC88075.1 - 0.02 14.6 1.5 0.02 14.6 1.1 2.1 2 0 0 2 2 2 0 Ion channel EF-hand_7 PF13499.1 EMC88076.1 - 3.9e-13 49.3 3.5 3.9e-13 49.3 2.4 3.8 4 2 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC88076.1 - 1.5e-09 36.4 2.8 0.00024 20.1 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EMC88076.1 - 5.2e-06 25.9 4.2 0.00012 21.6 0.4 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EMC88076.1 - 0.00054 19.1 4.0 0.0055 16.0 0.3 4.2 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 EMC88076.1 - 2.5 7.7 10.4 3 7.5 0.0 4.0 5 0 0 5 5 5 0 EF-hand domain pair SlyX PF04102.7 EMC88076.1 - 4.5 7.7 19.1 1.6 9.1 10.0 2.8 2 0 0 2 2 2 0 SlyX Ribosomal_S13_N PF08069.7 EMC88077.1 - 2.8e-18 65.5 0.1 3.1e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain PH PF00169.24 EMC88078.1 - 5e-15 55.5 0.0 1.7e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC88078.1 - 2.2e-09 37.5 0.0 1.1e-08 35.3 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMC88078.1 - 2.5e-05 24.2 0.0 0.022 14.7 0.0 2.9 1 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EMC88078.1 - 0.0014 18.8 0.2 0.017 15.2 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain HMG_box_5 PF14887.1 EMC88078.1 - 0.028 14.1 6.0 0.036 13.8 1.2 2.9 2 0 0 2 2 2 0 HMG (high mobility group) box 5 SMAP PF15477.1 EMC88079.1 - 2.3e-06 27.7 0.3 2.3e-06 27.7 0.2 2.5 2 1 0 2 2 2 1 Small acidic protein family RNA_polI_A34 PF08208.6 EMC88079.1 - 0.33 10.5 14.5 0.064 12.9 7.4 1.5 1 1 1 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.7 EMC88079.1 - 0.5 8.2 16.9 0.61 7.9 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EMC88079.1 - 0.56 9.2 18.4 0.67 8.9 12.7 1.1 1 0 0 1 1 1 0 BUD22 DUF2052 PF09747.4 EMC88079.1 - 0.64 9.9 13.9 0.88 9.4 9.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AUX_IAA PF02309.11 EMC88079.1 - 1.7 8.3 7.2 2.1 8.0 5.0 1.1 1 0 0 1 1 1 0 AUX/IAA family FAM60A PF15396.1 EMC88079.1 - 2.2 7.9 6.6 2.6 7.7 4.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.7 EMC88079.1 - 2.2 8.0 11.4 2.9 7.6 7.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EMC88079.1 - 2.5 6.0 14.4 2.9 5.8 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein FCP1_C PF09309.5 EMC88079.1 - 3 7.0 19.8 5.9 6.1 13.7 1.5 1 1 0 1 1 1 0 FCP1, C-terminal AF-4 PF05110.8 EMC88079.1 - 4.2 5.1 19.1 4.8 4.9 13.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein VID27 PF08553.5 EMC88079.1 - 4.9 5.2 11.2 5.7 5.0 7.8 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein DDHD PF02862.12 EMC88079.1 - 7 6.3 9.8 9.8 5.8 6.8 1.2 1 0 0 1 1 1 0 DDHD domain DUF3408 PF11888.3 EMC88079.1 - 7.3 6.5 13.9 20 5.0 9.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) NOA36 PF06524.7 EMC88079.1 - 8 5.6 11.0 10 5.2 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 EMC88079.1 - 8.6 5.1 9.7 10 4.9 6.7 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HMG_box PF00505.14 EMC88080.1 - 2.1e-22 79.1 4.3 6.8e-22 77.5 3.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC88080.1 - 6.8e-09 35.9 1.0 6.8e-09 35.9 0.7 3.2 3 0 0 3 3 3 1 HMG-box domain AAA_23 PF13476.1 EMC88080.1 - 0.24 11.6 13.5 0.52 10.6 8.1 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.9 EMC88080.1 - 2.9 7.8 25.3 3.2 7.6 0.1 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Arm PF00514.18 EMC88081.1 - 0.00046 19.9 12.2 0.0026 17.4 0.2 5.1 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat Ribosomal_S14 PF00253.16 EMC88081.1 - 0.1 12.0 0.5 0.64 9.4 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e CMS1 PF14617.1 EMC88081.1 - 0.19 10.8 1.9 1.6 7.7 0.0 3.1 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Calc_CGRP_IAPP PF00214.14 EMC88082.1 - 2.7e-31 108.3 0.1 3.1e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family p450 PF00067.17 EMC88083.1 - 5.8e-115 384.4 0.0 6.5e-115 384.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.21 EMC88084.1 - 3e-47 160.3 0.0 3.7e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC88084.1 - 9.4e-13 47.2 0.0 2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Adaptin_N PF01602.15 EMC88085.1 - 8.1e-121 403.9 9.3 1.3e-120 403.2 6.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EMC88085.1 - 1.6e-64 215.4 0.0 3.4e-64 214.3 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EMC88085.1 - 3.4e-62 208.2 0.2 8.5e-62 206.9 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EMC88085.1 - 3.1e-11 43.4 5.1 0.0004 20.6 0.0 6.0 3 1 2 6 6 6 2 HEAT repeats HEAT PF02985.17 EMC88085.1 - 9.5e-08 31.5 0.1 0.017 15.1 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EMC88085.1 - 5e-06 26.8 0.7 0.041 14.3 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 EMC88085.1 - 7.7e-05 22.6 11.6 0.063 13.1 0.0 4.6 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EMC88085.1 - 0.00017 21.3 0.1 2.7 7.9 0.0 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EMC88085.1 - 0.00025 20.3 0.1 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Ras PF00071.17 EMC88086.1 - 1.4e-47 161.0 0.3 1.7e-47 160.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88086.1 - 6.5e-12 46.0 0.0 1.5e-11 44.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMC88086.1 - 6e-07 29.0 0.0 7.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMC88086.1 - 6.7e-06 25.4 0.1 7.6e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EMC88086.1 - 0.0045 16.5 0.0 0.0056 16.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Tub PF01167.13 EMC88087.1 - 9.2e-118 391.6 0.0 9.2e-118 391.6 0.0 2.3 3 1 0 3 3 3 1 Tub family UpxZ PF06603.6 EMC88087.1 - 0.22 11.5 1.0 14 5.7 0.1 3.0 2 2 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists Macoilin PF09726.4 EMC88087.1 - 3.3 5.8 14.0 4.9 5.3 9.7 1.4 1 0 0 1 1 1 0 Transmembrane protein RIC3 PF15361.1 EMC88088.1 - 1e-37 129.7 0.1 2.7e-37 128.3 0.0 1.8 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 IER PF05760.7 EMC88088.1 - 0.1 12.5 9.7 0.14 12.0 6.7 1.4 1 1 0 1 1 1 0 Immediate early response protein (IER) DUF2408 PF10303.4 EMC88088.1 - 2.8 8.0 9.9 0.41 10.7 1.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2408) LIM PF00412.17 EMC88089.1 - 2e-30 104.6 22.0 2.5e-15 56.2 5.8 2.1 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 EMC88089.1 - 4.1 7.4 22.2 0.37 10.8 4.6 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Ribosomal_L18e PF00828.14 EMC88090.1 - 6.5e-38 130.0 0.4 7.8e-38 129.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RTC4 PF14474.1 EMC88090.1 - 0.15 11.9 0.3 0.96 9.4 0.1 2.0 1 1 1 2 2 2 0 RTC4-like domain DENN PF02141.16 EMC88091.1 - 4.1e-58 196.1 0.7 4.1e-58 196.1 0.5 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 EMC88091.1 - 2.8e-23 81.6 0.2 8.8e-23 80.0 0.2 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EMC88091.1 - 1.5e-21 76.2 3.8 3.3e-21 75.1 2.6 1.6 1 0 0 1 1 1 1 dDENN domain CarboxypepD_reg PF13620.1 EMC88092.1 - 0.00021 21.2 0.3 0.0003 20.7 0.2 1.4 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Tad_C PF09977.4 EMC88092.1 - 0.018 16.0 0.4 0.026 15.5 0.3 1.2 1 0 0 1 1 1 0 Putative Tad-like Flp pilus-assembly zf-C5HC2 PF02928.11 EMC88092.1 - 0.098 12.7 0.7 0.16 12.0 0.5 1.4 1 0 0 1 1 1 0 C5HC2 zinc finger DUF4537 PF15057.1 EMC88093.1 - 1.7e-36 124.7 0.0 2.3e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tmemb_9 PF05434.6 EMC88094.1 - 2.3e-74 248.1 0.4 2.7e-74 247.8 0.3 1.1 1 0 0 1 1 1 1 TMEM9 Neurensin PF14927.1 EMC88094.1 - 0.037 13.4 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Neurensin Asp_protease PF09668.5 EMC88095.1 - 6.8e-11 41.8 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EMC88095.1 - 1.6e-09 37.4 0.0 4.8e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EMC88095.1 - 1.1e-07 32.2 0.0 2.7e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EMC88095.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease PilO PF04350.8 EMC88095.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilO DENN PF02141.16 EMC88096.1 - 1.3e-60 204.2 5.2 2.5e-60 203.3 3.1 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.14 EMC88096.1 - 6.1e-26 90.7 5.8 1.9e-13 50.3 0.0 2.9 3 0 0 3 3 3 2 RUN domain uDENN PF03456.13 EMC88096.1 - 2.3e-20 72.2 0.6 6.9e-20 70.7 0.1 2.2 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 EMC88096.1 - 2.4e-20 72.3 4.5 6.1e-20 71.0 3.1 1.8 1 0 0 1 1 1 1 dDENN domain PLAT PF01477.18 EMC88096.1 - 4.8e-16 59.1 0.0 9.8e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain SNARE_assoc PF09335.6 EMC88097.1 - 1e-23 83.8 6.2 1e-23 83.8 4.3 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF3357 PF11837.3 EMC88097.1 - 0.018 14.8 0.3 0.077 12.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) IncA PF04156.9 EMC88097.1 - 1.1 8.7 6.4 2.3 7.7 0.0 2.6 3 0 0 3 3 3 0 IncA protein Phtf-FEM1B_bdg PF12129.3 EMC88097.1 - 6.1 6.1 7.1 4.9 6.4 0.8 2.5 2 1 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor zf-H2C2_2 PF13465.1 EMC88098.1 - 3.4e-42 140.7 50.9 3.6e-09 36.4 0.4 7.6 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.21 EMC88098.1 - 8e-28 95.0 47.6 8.1e-06 25.8 0.8 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC88098.1 - 6.7e-21 73.0 41.1 0.0046 17.2 0.4 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger CopK PF11525.3 EMC88098.1 - 2.4e-05 23.8 3.0 6 6.5 0.0 5.4 4 2 2 6 6 6 2 Copper resistance protein K zf-C2H2_jaz PF12171.3 EMC88098.1 - 0.0005 20.1 27.7 3.9 7.7 0.7 7.6 6 1 1 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EMC88098.1 - 0.0038 17.5 1.0 0.0038 17.5 0.7 3.9 3 1 1 4 4 4 1 TRAF-type zinc finger DUF2291 PF10054.4 EMC88098.1 - 0.041 13.1 3.9 0.49 9.6 0.2 2.6 2 1 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) Pkinase PF00069.20 EMC88099.1 - 1.7e-53 181.4 0.0 2.3e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88099.1 - 2.9e-27 95.4 0.0 3.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EMC88100.1 - 9.5e-19 67.5 0.8 3.7e-18 65.6 0.5 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC88100.1 - 5.6e-05 23.3 14.3 0.0002 21.5 2.8 3.9 2 2 1 3 3 3 1 Pleckstrin homology domain Calc_CGRP_IAPP PF00214.14 EMC88101.1 - 2.4e-33 114.9 0.0 2.7e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family zf-C3HC4_3 PF13920.1 EMC88102.1 - 9.3e-11 41.2 10.7 1.5e-10 40.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC88102.1 - 1.1e-10 41.1 13.3 2.1e-10 40.2 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC88102.1 - 2.2e-07 30.7 14.0 4.1e-07 29.9 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC88102.1 - 1.1e-06 28.1 12.5 2.1e-06 27.2 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC88102.1 - 4.5e-05 23.0 14.1 0.00025 20.6 9.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EMC88102.1 - 8.3e-05 22.0 5.7 0.00017 21.0 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EMC88102.1 - 0.00047 19.8 7.0 0.00082 19.0 3.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMC88102.1 - 0.0015 18.6 14.8 0.0099 15.9 10.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC88102.1 - 0.035 13.9 12.6 0.079 12.8 8.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sulfotransfer_2 PF03567.9 EMC88102.1 - 0.054 13.1 0.1 0.098 12.3 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family zf-RING_4 PF14570.1 EMC88102.1 - 0.28 10.8 11.8 0.61 9.7 8.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EMC88102.1 - 0.4 10.5 9.3 0.82 9.5 5.9 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EMC88102.1 - 1.3 8.5 7.8 0.49 9.9 0.3 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif Xlink PF00193.12 EMC88103.1 - 3.1e-19 68.8 0.1 5.7e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Extracellular link domain MGC-24 PF05283.6 EMC88103.1 - 0.00084 19.1 5.2 0.00084 19.1 3.6 2.0 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) DUF3068 PF11271.3 EMC88103.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) Nucleoside_tran PF01733.13 EMC88103.1 - 0.045 12.9 0.2 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter SID-1_RNA_chan PF13965.1 EMC88103.1 - 0.13 10.3 2.1 0.61 8.1 0.3 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TMEM154 PF15102.1 EMC88103.1 - 0.84 9.3 4.8 2.8 7.6 3.3 1.9 1 1 0 1 1 1 0 TMEM154 protein family OAD_gamma PF04277.8 EMC88103.1 - 0.88 9.9 3.9 3.2 8.1 2.7 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MRVI1 PF05781.7 EMC88104.1 - 1.2e-169 565.2 16.8 1.6e-169 564.7 11.6 1.1 1 0 0 1 1 1 1 MRVI1 protein DUF2799 PF10973.3 EMC88104.1 - 0.015 15.3 1.7 0.062 13.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2799) MIF4G PF02854.14 EMC88105.1 - 1.3e-57 194.5 1.4 1.3e-57 194.5 1.0 2.2 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.13 EMC88105.1 - 2.6e-21 75.3 1.3 2.8e-20 72.0 1.0 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.12 EMC88105.1 - 2.1e-11 43.5 5.7 2.5e-11 43.2 0.1 3.0 3 0 0 3 3 3 1 MA3 domain Glycos_transf_2 PF00535.21 EMC88106.1 - 2.6e-22 79.2 0.1 3.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC88106.1 - 1.5e-14 54.0 1.5 2.9e-14 53.1 1.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC88106.1 - 1.5e-06 28.1 0.1 0.031 14.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC88106.1 - 1.2e-05 24.6 0.0 3.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC88106.1 - 4.9e-05 22.5 0.0 7.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 UCH PF00443.24 EMC88107.1 - 2.4e-58 197.4 1.6 6.1e-58 196.0 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC88107.1 - 2e-32 112.8 0.4 2e-32 112.8 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.1 EMC88107.1 - 1.6e-08 34.6 0.1 0.082 13.1 0.0 4.1 4 0 0 4 4 4 3 Ubiquitin-like domain ubiquitin PF00240.18 EMC88107.1 - 1.6e-07 30.5 0.2 0.089 12.2 0.0 3.9 3 0 0 3 3 3 3 Ubiquitin family Ribosomal_S2 PF00318.15 EMC88107.1 - 0.046 12.9 0.1 0.51 9.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S2 CP2 PF04516.10 EMC88107.1 - 0.15 11.0 5.5 0.3 10.0 0.6 2.5 2 0 0 2 2 2 0 CP2 transcription factor Dickkopf_N PF04706.7 EMC88108.1 - 1.5e-18 66.6 19.9 1.5e-18 66.6 13.8 2.9 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.6 EMC88108.1 - 3.9e-05 23.6 5.4 3.9e-05 23.6 3.8 2.7 1 1 2 3 3 3 1 Prokineticin CH PF00307.26 EMC88109.1 - 1.3e-19 70.2 0.0 3.4e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC88109.1 - 2.8e-13 49.2 0.0 6.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.17 EMC88109.1 - 2e-09 37.3 10.7 4.8e-09 36.1 7.4 1.7 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.14 EMC88109.1 - 6.5e-07 28.7 0.0 1.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EMC88109.1 - 5.2e-05 22.2 0.0 7.6e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC88109.1 - 0.00012 22.0 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMC88109.1 - 0.00015 22.0 0.1 0.00052 20.3 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMC88109.1 - 0.00018 20.5 0.0 0.00032 19.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMC88109.1 - 0.00045 18.8 0.0 0.00078 18.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.1 EMC88109.1 - 0.00068 19.8 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EMC88109.1 - 0.006 15.5 0.0 0.014 14.3 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMC88109.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMC88109.1 - 0.007 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC88109.1 - 0.0077 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMC88109.1 - 0.012 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EMC88109.1 - 0.08 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3585 PF12130.3 EMC88110.1 - 5e-36 123.6 25.3 5e-36 123.6 17.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) DUF1823 PF08853.6 EMC88110.1 - 0.016 14.9 0.3 0.045 13.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) LMBR1 PF04791.11 EMC88110.1 - 4.1 5.8 8.8 7 5.1 6.1 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein CH PF00307.26 EMC88111.1 - 1.1e-11 44.7 0.6 1.8e-11 44.0 0.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC88111.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain FlaG PF03646.10 EMC88111.1 - 0.018 15.1 0.8 0.037 14.1 0.5 1.5 1 0 0 1 1 1 0 FlaG protein CH PF00307.26 EMC88112.1 - 4.1e-05 23.5 0.0 4.3e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain TEA PF01285.13 EMC88113.1 - 3.5e-173 576.7 0.0 4.2e-173 576.4 0.0 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EMC88113.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PAS_11 PF14598.1 EMC88114.1 - 1.2e-27 96.1 0.2 1.1e-22 80.1 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EMC88114.1 - 5.1e-21 74.5 0.0 2.4e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 EMC88114.1 - 3.7e-17 62.1 0.0 5.1e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 EMC88114.1 - 6.2e-17 61.0 0.7 1.1e-16 60.2 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EMC88114.1 - 1.6e-09 38.1 0.0 0.0028 17.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMC88114.1 - 2.4e-05 24.3 0.0 0.0085 16.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.6 EMC88114.1 - 0.084 13.3 0.0 0.23 11.9 0.0 1.7 2 0 0 2 2 2 0 PAS fold BTB_2 PF02214.17 EMC88115.1 - 0.00047 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Parathyroid PF01279.12 EMC88116.1 - 1.4e-23 83.4 2.2 1.7e-23 83.1 1.5 1.1 1 0 0 1 1 1 1 Parathyroid hormone family NAD_binding_4 PF07993.7 EMC88117.1 - 4.6e-76 255.0 0.0 5.9e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.14 EMC88117.1 - 6e-23 80.9 1.1 1.4e-22 79.7 0.8 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMC88117.1 - 6.7e-10 38.8 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC88117.1 - 2.9e-06 26.2 0.1 0.0099 14.6 0.1 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMC88117.1 - 0.00024 20.1 0.0 0.00066 18.6 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EMC88117.1 - 0.00099 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EMC88117.1 - 0.0021 16.9 0.2 2.5 6.8 0.1 3.1 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMC88117.1 - 0.0022 18.0 0.1 0.093 12.7 0.0 3.0 2 1 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 EMC88117.1 - 0.057 13.3 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EMC88117.1 - 0.061 13.2 0.2 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 short chain dehydrogenase KR PF08659.5 EMC88117.1 - 0.062 12.9 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 KR domain Trypsin PF00089.21 EMC88118.1 - 7.8e-66 221.7 0.0 8.8e-66 221.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC88118.1 - 4.8e-08 32.6 0.0 6.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC88118.1 - 0.0004 20.3 0.0 0.00099 19.0 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EMC88119.1 - 1.7e-73 246.8 0.1 1.9e-73 246.7 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC88119.1 - 1.1e-11 44.4 0.3 1.7e-11 43.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC88119.1 - 0.00025 21.0 0.0 0.00055 19.9 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain SAM_1 PF00536.25 EMC88120.1 - 2.1e-40 136.7 5.9 2.1e-18 66.2 0.0 4.3 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC88120.1 - 1.5e-39 133.6 3.5 5.7e-15 54.9 0.0 3.9 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Integrase_DNA PF02920.10 EMC88120.1 - 4.2e-20 70.9 11.0 9.7e-20 69.7 7.6 1.7 1 0 0 1 1 1 1 DNA binding domain of tn916 integrase Reo_sigmaC PF04582.7 EMC88120.1 - 0.02 14.0 5.9 0.052 12.7 1.5 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein SAM_PNT PF02198.11 EMC88120.1 - 0.25 11.1 3.4 6.3 6.6 0.0 3.3 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain ADIP PF11559.3 EMC88120.1 - 1 9.2 30.1 1.3 8.9 11.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 EMC88120.1 - 1 10.1 15.4 0.57 10.9 3.3 3.0 1 1 1 2 2 2 0 Occludin homology domain OLF PF02191.11 EMC88121.1 - 2.8e-74 249.5 0.0 3.6e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain C2 PF00168.25 EMC88122.1 - 2.6e-57 190.6 0.3 1.6e-28 98.3 0.1 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 EMC88122.1 - 0.013 15.2 0.0 7.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.1 EMC88122.1 - 0.023 14.1 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain PAD_N PF08526.5 EMC88122.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) N-terminal domain TSP_1 PF00090.14 EMC88123.1 - 3.8e-83 273.4 85.8 2e-16 59.8 4.1 6.7 6 0 0 6 6 6 6 Thrombospondin type 1 domain Spond_N PF06468.8 EMC88123.1 - 4.4e-79 264.7 0.2 7.7e-79 263.9 0.1 1.4 1 0 0 1 1 1 1 Spondin_N Reeler PF02014.11 EMC88123.1 - 6.5e-32 110.5 0.0 1.3e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 Reeler domain DUF3827 PF12877.2 EMC88124.1 - 4.9e-258 857.7 8.8 4.9e-258 857.7 6.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3827) Pkinase PF00069.20 EMC88125.1 - 1.9e-50 171.4 0.0 3.7e-50 170.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88125.1 - 6.6e-24 84.3 0.0 1.2e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC88125.1 - 9.2e-06 24.8 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC88125.1 - 0.0033 17.2 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC88125.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Suf PF05843.9 EMC88126.1 - 3.3e-87 292.7 2.8 3.9e-84 282.7 0.0 4.0 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMC88126.1 - 0.00012 22.4 0.7 0.13 12.9 0.0 4.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC88126.1 - 0.00094 19.7 0.7 0.0082 16.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC88126.1 - 0.0035 17.6 0.4 0.17 12.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC88126.1 - 0.013 15.8 5.2 0.071 13.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EMC88126.1 - 0.03 13.1 18.0 0.78 8.5 3.1 5.5 2 1 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 EMC88126.1 - 0.055 13.1 9.1 2.9 7.6 2.1 3.6 2 1 1 3 3 3 0 TPR repeat HAT PF02184.11 EMC88126.1 - 6 6.6 7.5 10 5.9 0.0 4.5 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat Tcp11 PF05794.8 EMC88127.1 - 4.3e-129 431.0 0.1 5.2e-129 430.7 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1819 PF08849.6 EMC88127.1 - 0.073 12.4 0.3 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) EF_TS PF00889.14 EMC88127.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor TS DEP PF00610.16 EMC88128.1 - 4.7e-16 58.2 1.0 4.3e-15 55.2 0.1 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Imm16 PF15565.1 EMC88128.1 - 0.037 13.8 0.1 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 16 DUF4211 PF13926.1 EMC88129.1 - 1.2e-33 115.6 0.4 3.7e-33 114.1 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Gla PF00594.15 EMC88131.1 - 1.5e-14 53.3 5.1 2.8e-14 52.5 3.6 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain CD34_antigen PF06365.7 EMC88131.1 - 0.0003 20.5 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family EphA2_TM PF14575.1 EMC88131.1 - 0.00082 19.7 0.2 0.0018 18.6 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMC88131.1 - 0.0017 18.5 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.6 EMC88131.1 - 0.0022 17.7 0.3 0.0041 16.8 0.2 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 WBP-1 PF11669.3 EMC88131.1 - 0.017 15.1 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 Adeno_E3_CR2 PF02439.10 EMC88131.1 - 0.037 13.5 4.0 0.066 12.7 2.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM190 PF15431.1 EMC88131.1 - 0.073 12.9 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 Transmembrane protein 190 IncA PF04156.9 EMC88131.1 - 0.17 11.5 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 IncA protein ATP1G1_PLM_MAT8 PF02038.11 EMC88131.1 - 0.75 8.8 2.7 0.72 8.9 0.5 1.9 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Mst1_SARAH PF11629.3 EMC88132.1 - 1.8 8.4 13.3 1.8 8.4 1.2 4.1 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Lipoprotein_20 PF13942.1 EMC88132.1 - 5.5 6.4 42.7 0.18 11.3 7.1 4.2 2 2 2 4 4 4 0 YfhG lipoprotein PCI PF01399.22 EMC88133.1 - 3.4e-15 56.2 1.5 2.3e-14 53.5 0.6 2.4 2 0 0 2 2 2 1 PCI domain Death PF00531.17 EMC88133.1 - 0.075 12.8 1.2 1.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Death domain WT1 PF02165.10 EMC88135.1 - 1.3e-136 454.4 14.7 8.2e-119 396.0 4.8 2.1 1 1 1 2 2 2 2 Wilm's tumour protein zf-H2C2_2 PF13465.1 EMC88135.1 - 9.2e-16 57.2 40.2 3.1e-07 30.3 1.9 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC88135.1 - 1.5e-15 56.4 39.0 1.9e-05 24.7 2.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC88135.1 - 9e-09 35.0 32.8 0.00075 19.6 1.6 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EMC88135.1 - 0.024 14.8 2.3 0.024 14.8 1.6 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Ofd1_CTDD PF10637.4 EMC88135.1 - 0.16 11.0 2.6 0.18 10.9 0.9 1.6 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term zinc_ribbon_4 PF13717.1 EMC88135.1 - 0.41 10.3 3.8 36 4.1 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain CCAP PF11105.3 EMC88135.1 - 3.1 7.5 6.1 0.55 9.9 0.2 2.1 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a EF-hand_7 PF13499.1 EMC88136.1 - 5.3e-20 71.3 17.2 5.4e-09 36.0 0.2 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EMC88136.1 - 4.8e-18 63.0 16.7 0.002 17.3 0.5 6.8 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.1 EMC88136.1 - 1.8e-16 58.4 14.7 0.0071 16.1 0.0 6.5 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.1 EMC88136.1 - 1.9e-07 30.0 27.0 0.0006 19.0 0.6 6.5 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.1 EMC88136.1 - 1.2e-06 27.9 17.4 0.017 14.7 0.4 6.3 5 2 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC88136.1 - 0.00042 20.3 9.1 0.072 13.1 0.2 3.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.6 EMC88136.1 - 0.031 14.3 0.3 0.75 9.8 0.0 2.9 3 1 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like DUF2852 PF11014.3 EMC88136.1 - 0.086 12.7 3.6 0.27 11.1 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) DUF3887 PF13026.1 EMC88136.1 - 0.61 10.4 6.3 0.43 10.8 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3887) DUF1965 PF09248.5 EMC88136.1 - 0.9 9.4 5.3 3 7.8 0.1 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF1965) EF-hand_4 PF12763.2 EMC88136.1 - 2.1 8.1 12.0 1.4 8.6 0.2 4.2 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand PAXNEB PF05625.6 EMC88137.1 - 1.3e-110 369.7 0.0 1.4e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein DUF3926 PF13080.1 EMC88137.1 - 0.31 10.6 1.9 8 6.0 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3926) Peptidase_S24 PF00717.18 EMC88138.1 - 2.6e-14 52.6 0.0 4.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EMC88138.1 - 2.3e-07 30.3 0.0 0.00035 20.1 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DnaJ PF00226.26 EMC88139.1 - 2.3e-19 68.8 0.5 3.2e-19 68.4 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EMC88139.1 - 1.1e-11 43.9 6.2 1.8e-11 43.3 4.3 1.3 1 0 0 1 1 1 1 CSL zinc finger fn1 PF00039.13 EMC88139.1 - 0.035 13.8 1.7 0.1 12.4 1.2 1.7 1 0 0 1 1 1 0 Fibronectin type I domain Metallophos PF00149.23 EMC88140.1 - 3.3e-09 36.4 2.5 7.7e-09 35.2 1.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC88140.1 - 9e-06 25.6 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ARF7EP_C PF14949.1 EMC88141.1 - 2.9e-36 124.0 6.6 2.9e-36 124.0 4.5 1.8 2 0 0 2 2 2 1 ARF7 effector protein C-terminus Cys_knot PF00007.17 EMC88142.1 - 1.2e-30 105.6 17.2 1.5e-30 105.3 12.0 1.1 1 0 0 1 1 1 1 Cystine-knot domain Methyltransf_5 PF01795.14 EMC88143.1 - 5.1e-87 292.0 0.0 1.3e-85 287.3 0.0 2.0 1 1 0 1 1 1 1 MraW methylase family Methyltransf_18 PF12847.2 EMC88143.1 - 2.3e-05 24.9 0.0 0.0019 18.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC88143.1 - 0.00038 20.4 0.0 0.0027 17.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC88143.1 - 0.0018 17.8 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 EMC88143.1 - 0.0023 17.1 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EMC88143.1 - 0.0028 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EMC88143.1 - 0.0039 16.5 0.0 0.36 10.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EMC88143.1 - 0.0063 16.9 0.1 0.5 10.8 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_15 PF09445.5 EMC88143.1 - 0.026 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Adenine_glyco PF03352.8 EMC88143.1 - 0.065 12.7 0.2 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Methyladenine glycosylase Met_10 PF02475.11 EMC88143.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.7 EMC88143.1 - 0.14 12.6 0.0 2.6 8.5 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Kinesin PF00225.18 EMC88144.1 - 7.4e-114 379.9 0.6 7.4e-114 379.9 0.4 2.3 2 0 0 2 2 2 1 Kinesin motor domain NGF PF00243.13 EMC88145.1 - 5.2e-59 197.0 3.5 7.2e-59 196.6 2.4 1.2 1 0 0 1 1 1 1 Nerve growth factor family PDZ PF00595.19 EMC88146.1 - 2.9e-21 75.4 0.6 4.3e-21 74.8 0.4 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 EMC88146.1 - 1.2e-20 72.8 0.2 2.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 L27 domain PDZ_2 PF13180.1 EMC88146.1 - 0.00057 19.7 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF2057 PF09829.4 EMC88146.1 - 0.0039 16.8 0.5 0.0097 15.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) LRR_8 PF13855.1 EMC88147.1 - 2.9e-30 103.8 15.2 2.5e-14 52.7 1.6 4.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EMC88147.1 - 9.7e-20 69.7 18.5 2.2e-10 39.9 0.1 6.1 3 3 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC88147.1 - 1.6e-16 57.7 16.0 0.0044 16.8 0.1 7.8 8 0 0 8 8 8 5 Leucine Rich Repeat 7tm_1 PF00001.16 EMC88147.1 - 3.3e-16 59.2 12.6 5.1e-16 58.5 8.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.1 EMC88147.1 - 2e-13 50.1 0.1 2.5e-07 30.4 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC88147.1 - 8.8e-09 34.5 13.9 0.39 10.9 0.0 7.0 6 0 0 6 6 6 4 Leucine Rich repeat LRR_7 PF13504.1 EMC88147.1 - 3e-07 29.5 13.2 0.7 10.3 0.1 7.5 8 0 0 8 8 8 3 Leucine rich repeat LRR_9 PF14580.1 EMC88147.1 - 0.00012 21.7 0.2 0.00037 20.0 0.1 1.8 1 1 1 2 2 2 1 Leucine-rich repeat DUF4207 PF13904.1 EMC88148.1 - 2.6e-36 125.3 40.6 3.5e-36 124.9 28.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DUF3824 PF12868.2 EMC88148.1 - 0.011 16.6 6.9 0.011 16.6 4.7 3.0 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) SAPS PF04499.10 EMC88148.1 - 0.014 14.0 7.1 0.015 13.9 4.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TauD PF02668.11 EMC88149.1 - 1e-47 163.0 0.0 1.5e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EMC88149.1 - 2.2e-11 43.9 0.6 4.5e-05 23.7 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.5 EMC88149.1 - 0.00073 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 CsiD DSBA PF01323.15 EMC88149.1 - 0.11 11.9 0.2 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 DSBA-like thioredoxin domain SSF PF00474.12 EMC88151.1 - 1.4e-37 129.3 23.6 1.8e-37 128.9 16.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family NdhL PF10716.4 EMC88151.1 - 0.026 14.2 2.0 0.18 11.6 1.0 2.6 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit Leu_zip PF15294.1 EMC88152.1 - 1.5e-63 214.5 32.4 1.8e-63 214.3 22.4 1.0 1 0 0 1 1 1 1 Leucine zipper Reo_sigmaC PF04582.7 EMC88152.1 - 0.0056 15.9 3.7 0.0056 15.9 2.6 1.9 1 1 0 2 2 2 1 Reovirus sigma C capsid protein DUF4107 PF13389.1 EMC88152.1 - 0.0058 16.3 0.1 0.0091 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Fib_alpha PF08702.5 EMC88152.1 - 0.06 13.4 23.1 0.42 10.7 9.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2119 PF09892.4 EMC88152.1 - 0.063 12.5 2.2 1.1 8.5 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) BAR PF03114.13 EMC88152.1 - 0.22 10.9 22.9 0.29 10.5 15.9 1.2 1 0 0 1 1 1 0 BAR domain DUF1612 PF07756.7 EMC88152.1 - 0.3 11.1 8.3 8.9 6.4 0.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) LAGLIDADG_1 PF00961.14 EMC88152.1 - 0.56 10.7 3.5 1 9.9 2.5 1.5 1 0 0 1 1 1 0 LAGLIDADG endonuclease CTNNB1_binding PF08347.6 EMC88152.1 - 0.6 10.3 7.1 0.7 10.1 4.8 1.4 1 1 0 1 1 1 0 N-terminal CTNNB1 binding EzrA PF06160.7 EMC88152.1 - 0.63 8.1 26.2 1.5 6.8 18.1 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3584 PF12128.3 EMC88152.1 - 0.67 7.2 28.1 0.97 6.6 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FTCD_C PF04961.7 EMC88152.1 - 1.2 8.5 10.2 0.16 11.3 3.7 2.1 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase IncA PF04156.9 EMC88152.1 - 1.2 8.6 39.2 1 8.9 11.6 2.9 1 1 2 3 3 3 0 IncA protein SSFA2_C PF14723.1 EMC88152.1 - 1.5 8.5 14.3 0.54 9.9 6.3 2.1 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus Filament PF00038.16 EMC88152.1 - 1.9 7.8 30.3 1.6 8.1 11.6 2.4 1 1 0 2 2 2 0 Intermediate filament protein Cep57_CLD_2 PF14197.1 EMC88152.1 - 2.4 8.1 30.5 1.6 8.7 2.1 3.6 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 MAD PF05557.8 EMC88152.1 - 3.4 5.6 35.6 4.6 5.1 24.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.6 EMC88152.1 - 3.7 6.1 33.7 2.4 6.7 16.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein WEMBL PF05701.6 EMC88152.1 - 4.7 5.5 35.2 4.6 5.5 16.9 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Glyco_hydro_63 PF03200.11 EMC88152.1 - 4.8 4.8 9.6 5.5 4.6 6.7 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase TMEM192 PF14802.1 EMC88152.1 - 7.6 5.3 7.9 60 2.3 5.5 2.1 1 1 0 1 1 1 0 TMEM192 family Phage_GP20 PF06810.6 EMC88152.1 - 8 5.8 38.0 1.3 8.4 4.2 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 PhoU PF01895.14 EMC88152.1 - 8.2 6.9 11.0 1.7 9.1 2.4 2.9 3 0 0 3 3 3 0 PhoU domain GAS2 PF02187.12 EMC88153.1 - 5.1e-36 122.2 0.2 8.6e-36 121.5 0.2 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 EMC88153.1 - 4.7e-08 33.0 0.0 7.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain MFS_1 PF07690.11 EMC88154.1 - 5.2e-50 170.1 24.8 1.3e-48 165.5 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.17 EMC88156.1 - 6.7e-41 139.3 0.1 2.2e-40 137.7 0.1 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC88156.1 - 8.9e-18 64.9 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC88156.1 - 1.1e-14 54.0 0.1 1.4e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC88156.1 - 3.5e-05 23.0 0.1 5.1e-05 22.5 0.0 1.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMC88156.1 - 0.00024 20.4 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EMC88156.1 - 0.001 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EMC88156.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EMC88156.1 - 0.0026 17.7 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.6 EMC88156.1 - 0.013 14.1 0.3 0.62 8.6 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.1 EMC88156.1 - 0.035 14.2 0.0 0.057 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EMC88156.1 - 0.07 12.6 0.3 2 7.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 EMC88156.1 - 0.095 12.8 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMC88156.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EMC88156.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_M20 PF01546.23 EMC88157.1 - 2.1e-28 99.1 0.0 3.8e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMC88157.1 - 9.7e-17 60.7 0.0 1.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Sulfate_transp PF00916.15 EMC88158.1 - 5.3e-54 183.1 13.0 5.3e-54 183.1 9.0 2.0 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMC88158.1 - 3.3e-27 93.9 1.4 3.3e-27 93.9 1.0 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMC88158.1 - 1.1e-25 89.3 0.0 1.7e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain Ras PF00071.17 EMC88159.1 - 1.8e-32 112.0 0.0 1.9e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88159.1 - 5.7e-10 39.7 0.0 9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC88159.1 - 7.5e-09 35.0 0.0 7.6e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC88159.1 - 0.00034 20.0 0.0 0.00063 19.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Asp PF00026.18 EMC88160.1 - 1.5e-124 415.3 0.1 1.8e-124 415.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC88160.1 - 1.7e-09 37.8 0.2 8.7e-09 35.5 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 EMC88160.1 - 4e-06 26.4 0.7 6.2e-06 25.8 0.5 1.3 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.1 EMC88160.1 - 0.00032 21.1 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMC88160.1 - 0.019 14.4 0.0 0.73 9.3 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Na_trans_assoc PF06512.8 EMC88161.1 - 0.088 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated 7tm_1 PF00001.16 EMC88162.1 - 3.4e-56 190.2 8.7 4.1e-56 189.9 6.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88162.1 - 3e-09 36.4 4.4 4.6e-09 35.8 3.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC88162.1 - 5.2e-06 25.7 0.0 1.2e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.16 EMC88162.1 - 0.0031 16.9 4.2 0.0031 16.9 2.9 2.1 2 1 0 2 2 2 1 Srg family chemoreceptor RhoGAP PF00620.22 EMC88163.1 - 1e-47 161.5 0.8 7.1e-47 158.8 0.0 2.8 2 1 1 3 3 3 1 RhoGAP domain FCH PF00611.18 EMC88163.1 - 4.8e-20 71.5 3.8 3.6e-19 68.7 2.6 2.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMC88163.1 - 6.3e-10 38.4 0.0 1.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC88163.1 - 9.9e-10 37.6 0.0 1.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC88163.1 - 8.8e-09 34.7 0.0 1.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 EMC88163.1 - 0.0087 15.9 6.8 0.029 14.2 1.8 3.3 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Rnf-Nqr PF02508.9 EMC88163.1 - 0.34 10.4 0.2 0.59 9.6 0.1 1.3 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein KIP1 PF07765.7 EMC88163.1 - 0.85 9.5 5.0 4.8 7.0 0.3 3.2 3 0 0 3 3 3 0 KIP1-like protein Pkinase PF00069.20 EMC88164.1 - 1e-40 139.5 0.0 1.6e-40 138.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88164.1 - 9.5e-25 87.1 0.0 1.3e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC88164.1 - 0.0005 19.1 0.0 0.00087 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMC88164.1 - 0.095 12.4 0.0 1.3 8.7 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family CortBP2 PF09727.4 EMC88165.1 - 2.5e-58 196.8 16.9 2.5e-58 196.8 11.7 2.2 1 1 1 2 2 2 1 Cortactin-binding protein-2 Striatin PF08232.7 EMC88165.1 - 0.019 15.2 2.5 0.019 15.2 1.7 3.4 2 1 1 3 3 3 0 Striatin family DUF3584 PF12128.3 EMC88165.1 - 0.84 6.8 28.3 1.3 6.2 19.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.4 EMC88165.1 - 1.2 7.4 26.1 0.0063 14.9 4.1 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.1 EMC88165.1 - 3.7 5.8 24.4 6.5 5.0 16.9 1.4 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 EMC88165.1 - 4.2 7.3 47.8 3.4 7.6 14.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3399 PF11879.3 EMC88166.1 - 3.5e-47 158.9 7.9 1.1e-46 157.3 5.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) Ion_trans PF00520.26 EMC88166.1 - 1.8e-30 105.6 14.0 2.9e-30 105.0 9.0 1.8 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC88166.1 - 5.7e-29 100.1 0.1 1.7e-28 98.6 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain Shal-type PF11601.3 EMC88166.1 - 8.3e-16 57.1 13.9 1.4e-15 56.4 9.6 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels Ion_trans_2 PF07885.11 EMC88166.1 - 5e-13 48.5 6.0 5e-13 48.5 4.2 2.5 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 EMC88166.1 - 0.0046 15.4 11.2 0.0085 14.5 7.8 1.4 1 1 0 1 1 1 1 Polycystin cation channel DEAD PF00270.24 EMC88167.1 - 7.7e-29 100.3 0.0 1.6e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC88167.1 - 2.1e-21 75.5 0.0 5.3e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC88167.1 - 0.00013 21.8 0.5 0.00073 19.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EMC88167.1 - 0.00046 19.8 0.1 0.00093 18.9 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EMC88167.1 - 0.065 13.3 0.0 0.27 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMC88167.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.1 EMC88167.1 - 0.15 11.0 0.0 0.15 11.0 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FAM212 PF15342.1 EMC88168.1 - 3e-29 100.4 0.7 7.1e-29 99.1 0.5 1.7 1 0 0 1 1 1 1 FAM212 family Ras PF00071.17 EMC88169.1 - 4.1e-34 117.2 0.1 4.8e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88169.1 - 3e-12 47.0 0.0 5.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMC88169.1 - 6e-06 25.8 0.1 1.3e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMC88169.1 - 4e-05 22.9 0.0 5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family 7tm_2 PF00002.19 EMC88170.1 - 3.6e-67 225.9 19.9 5.5e-67 225.3 13.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC88170.1 - 7.3e-17 61.1 8.3 1.5e-16 60.1 5.8 1.5 1 0 0 1 1 1 1 Hormone receptor domain UPF0560 PF10577.4 EMC88171.1 - 8.5e-234 778.4 21.4 3.8e-140 468.6 2.7 2.0 1 1 1 2 2 2 2 Uncharacterised protein family UPF0560 Prominin PF05478.6 EMC88171.1 - 0.0027 15.3 0.0 0.004 14.7 0.0 1.1 1 0 0 1 1 1 1 Prominin OPA3 PF07047.7 EMC88171.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) FAM163 PF15069.1 EMC88171.1 - 0.12 12.9 4.8 0.13 12.8 1.4 2.4 2 1 0 2 2 2 0 FAM163 family Integrin_alpha2 PF08441.7 EMC88172.1 - 1.7e-112 376.6 0.0 2.1e-112 376.3 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 EMC88172.1 - 1.1e-23 82.2 21.7 1.7e-07 30.7 0.5 4.5 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.1 EMC88172.1 - 6.4e-14 52.0 8.7 5.3e-05 23.4 0.3 4.5 3 1 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 EMC88172.1 - 4.4e-05 22.9 0.9 9.4e-05 21.9 0.6 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region TcdB_toxin_midN PF12256.3 EMC88172.1 - 0.0097 15.3 1.5 0.74 9.2 0.1 3.2 2 1 1 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region DUF1049 PF06305.6 EMC88172.1 - 0.025 14.0 0.2 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CD34_antigen PF06365.7 EMC88172.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1191 PF06697.7 EMC88172.1 - 0.21 10.3 0.0 0.36 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) zf-CCCH PF00642.19 EMC88173.1 - 7.7e-06 25.4 0.8 7.7e-06 25.4 0.6 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMC88173.1 - 0.0052 16.7 10.9 0.11 12.5 3.3 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type HJURP_C PF12347.3 EMC88179.1 - 1.6 8.3 27.2 18 5.0 0.6 6.8 1 1 7 8 8 8 0 Holliday junction regulator protein family C-terminal repeat Keratin PF02422.11 EMC88181.1 - 5.8e-45 151.2 19.4 6.6e-45 151.0 13.4 1.0 1 0 0 1 1 1 1 Keratin Cadherin PF00028.12 EMC88182.1 - 3.4e-59 197.0 0.3 1.6e-16 60.2 0.0 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC88182.1 - 1.5e-10 41.2 0.0 3.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC88182.1 - 0.0021 17.5 0.0 8.9 5.9 0.0 3.5 3 0 0 3 3 3 2 Cadherin-like Transthyretin PF00576.16 EMC88183.1 - 2.6e-38 130.3 0.1 3.1e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Transthyretin PF00576.16 EMC88184.1 - 5.6e-35 119.6 0.0 6.6e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF290 PF01060.18 EMC88184.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Transthyretin-like family Glyco_transf_7N PF13733.1 EMC88185.1 - 1.1e-43 147.9 0.0 1.6e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 EMC88185.1 - 1.5e-27 94.8 0.9 2.7e-27 94.0 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC88185.1 - 4e-08 32.6 0.2 0.00036 19.7 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 7tm_1 PF00001.16 EMC88186.1 - 1.9e-41 141.9 16.1 2.1e-41 141.7 11.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88186.1 - 0.0018 17.5 13.2 0.0022 17.1 9.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TAS2R PF05296.8 EMC88186.1 - 0.0033 16.3 9.4 0.019 13.8 0.2 2.0 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) DUF4349 PF14257.1 EMC88186.1 - 0.29 10.3 1.8 0.22 10.7 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) 7tm_4 PF13853.1 EMC88186.1 - 2.6 7.8 19.2 0.047 13.4 4.0 2.6 2 1 0 2 2 2 0 Olfactory receptor TRAPPC-Trs85 PF12739.2 EMC88187.1 - 3.1e-06 26.1 0.0 3.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit zf-Di19 PF05605.7 EMC88188.1 - 8e-15 54.7 1.9 8e-15 54.7 1.3 3.7 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4 PF00097.20 EMC88188.1 - 2.8e-09 36.4 10.1 2.8e-09 36.4 7.0 4.0 3 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC88188.1 - 8.5e-09 35.1 10.6 8.5e-09 35.1 7.3 3.9 3 1 2 5 5 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC88188.1 - 3e-08 33.5 10.6 3e-08 33.5 7.3 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC88188.1 - 2.7e-07 30.1 3.4 2.7e-07 30.1 2.4 3.4 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EMC88188.1 - 6.3e-07 28.9 7.3 6.3e-07 28.9 5.0 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 EMC88188.1 - 9.3e-07 28.2 16.7 2.3e-05 23.8 5.1 3.4 3 0 0 3 3 3 2 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 EMC88188.1 - 1.7e-06 27.6 10.4 1.7e-06 27.6 7.2 4.0 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC88188.1 - 4.4e-06 26.4 9.2 4.4e-06 26.4 6.4 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EMC88188.1 - 2.8e-05 23.5 6.8 2.8e-05 23.5 4.7 2.8 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EMC88188.1 - 8.2e-05 22.3 3.6 8.2e-05 22.3 2.5 2.8 2 1 1 3 3 3 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EMC88188.1 - 0.00021 20.7 2.5 0.00021 20.7 1.7 4.3 5 0 0 5 5 5 1 RING/Ubox like zinc-binding domain U-box PF04564.10 EMC88188.1 - 0.0081 16.0 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 U-box domain GAGA PF09237.6 EMC88188.1 - 0.83 9.2 18.0 0.089 12.3 1.0 4.4 3 1 1 4 4 4 0 GAGA factor Astacin PF01400.19 EMC88189.1 - 1.5e-70 236.5 0.1 2.3e-70 235.8 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.18 EMC88189.1 - 4.4e-40 137.0 1.3 2.2e-39 134.8 0.1 2.4 3 0 0 3 3 3 1 MAM domain MATH PF00917.21 EMC88189.1 - 7.8e-27 93.8 0.0 1.6e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 MATH domain EGF PF00008.22 EMC88189.1 - 4.4e-05 23.3 2.9 0.00012 21.9 2.0 1.8 1 0 0 1 1 1 1 EGF-like domain DAG1 PF05454.6 EMC88189.1 - 0.017 14.3 0.1 0.024 13.8 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EGF_2 PF07974.8 EMC88189.1 - 0.065 13.4 5.6 0.17 12.0 3.9 1.8 1 0 0 1 1 1 0 EGF-like domain Peptidase_M91 PF14891.1 EMC88189.1 - 0.13 12.2 0.1 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Effector protein CABIT PF12736.2 EMC88190.1 - 1.2e-51 175.1 0.7 2e-51 174.4 0.3 1.5 2 0 0 2 2 2 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.25 EMC88190.1 - 0.0019 18.2 0.1 0.0035 17.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras PF00071.17 EMC88191.1 - 1.8e-45 154.2 0.0 2.4e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88191.1 - 2.6e-11 44.0 0.0 4.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC88191.1 - 6.5e-09 35.2 0.0 9e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC88191.1 - 1.9e-05 24.1 0.0 2.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC88191.1 - 0.00085 18.5 0.0 0.0012 18.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Sad1_UNC PF07738.8 EMC88193.1 - 8.2e-20 70.9 0.0 1.5e-19 70.0 0.0 1.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal TLV_coat PF00429.14 EMC88194.1 - 9.7e-05 21.0 1.6 0.0001 20.9 1.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) 7tm_4 PF13853.1 EMC88195.1 - 6.9e-59 197.7 13.9 6.9e-59 197.7 9.6 2.3 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC88195.1 - 3e-31 108.4 19.4 3.8e-31 108.1 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC88196.1 - 7.6e-64 213.8 11.1 7.6e-64 213.8 7.7 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC88196.1 - 1.1e-36 126.2 16.5 1.4e-36 125.9 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC88197.1 - 2.4e-40 137.6 10.8 4.3e-40 136.8 7.5 1.4 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC88197.1 - 9.7e-28 96.9 17.2 1.2e-27 96.7 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC88198.1 - 1.9e-60 202.8 13.9 1.9e-60 202.8 9.6 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC88198.1 - 1.3e-33 116.1 18.8 1.8e-33 115.7 13.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC88199.1 - 1.1e-22 80.3 4.1 1.1e-22 80.3 2.8 2.1 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC88199.1 - 2.6e-16 59.5 9.8 1.3e-14 54.0 6.8 2.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Het-C PF07217.6 EMC88200.1 - 0.086 11.0 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Arm_2 PF04826.8 EMC88200.1 - 0.099 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Armadillo-like DWNN PF08783.6 EMC88201.1 - 1.9e-13 50.1 0.1 3e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 DWNN domain Ank_2 PF12796.2 EMC88202.1 - 9.2e-18 64.3 1.0 1.5e-11 44.4 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC88202.1 - 1.2e-15 56.4 1.9 7.5e-07 28.6 0.3 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMC88202.1 - 8.4e-15 53.4 0.5 5.5e-06 26.1 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMC88202.1 - 1.9e-12 47.3 4.0 3.2e-08 33.8 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC88202.1 - 9.9e-12 44.7 3.4 0.0001 22.4 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-DHHC PF01529.15 EMC88203.1 - 9e-41 139.1 3.3 1.3e-40 138.6 2.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Peptidase_M24 PF00557.19 EMC88204.1 - 2.9e-33 115.2 0.0 3.5e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMC88205.1 - 0.00027 21.4 0.0 0.00034 21.1 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF218 PF02698.12 EMC88205.1 - 0.12 11.8 0.4 0.18 11.2 0.2 1.3 1 1 0 1 1 1 0 DUF218 domain Exo_endo_phos PF03372.18 EMC88206.1 - 1.5e-31 110.2 0.0 2.5e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EMC88206.1 - 2.2e-25 89.0 0.2 4e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Minor_capsid_3 PF12691.2 EMC88206.1 - 0.076 12.7 0.1 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Sigma70_r1_1 PF03979.9 EMC88206.1 - 0.087 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 SNF2_N PF00176.18 EMC88207.1 - 5.4e-59 199.4 0.1 1.9e-58 197.6 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC88207.1 - 3.6e-16 58.7 0.2 8e-14 51.2 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMC88207.1 - 1.8e-10 40.9 0.0 4.5e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC88207.1 - 4.3e-07 29.5 0.0 1.4e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EMC88207.1 - 1.2e-06 27.5 0.0 2.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 EMC88207.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Rotamase_3 PF13616.1 EMC88208.1 - 4.3e-20 72.1 0.0 1.3e-19 70.5 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EMC88208.1 - 4.9e-19 68.8 0.0 8.1e-19 68.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EMC88208.1 - 2.6e-05 24.8 0.0 3.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain NHS PF15273.1 EMC88209.1 - 5.7e-33 114.5 43.1 7.5e-29 100.8 16.5 3.1 3 0 0 3 3 3 2 NHS-like Amidase PF01425.16 EMC88211.1 - 4.8e-88 295.9 0.0 6.2e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Crystall PF00030.14 EMC88214.1 - 0.083 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin 7tm_1 PF00001.16 EMC88215.1 - 1.7e-39 135.5 22.7 2.1e-39 135.2 15.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3611 PF12263.3 EMC88215.1 - 0.012 15.0 0.8 0.012 15.0 0.6 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3611) DUF2917 PF11142.3 EMC88215.1 - 0.043 13.0 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) DUF2852 PF11014.3 EMC88215.1 - 0.37 10.7 3.4 5.2 7.0 2.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) NfeD PF01957.13 EMC88215.1 - 3.1 7.9 6.9 1.9 8.6 0.3 2.6 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2976 PF11190.3 EMC88215.1 - 5.6 6.5 12.2 0.14 11.7 2.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) 7tm_1 PF00001.16 EMC88216.1 - 2.2e-43 148.2 21.6 2.9e-43 147.8 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC88216.1 - 0.0074 15.4 32.6 0.093 11.8 22.5 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx P12 PF12669.2 EMC88216.1 - 1.8 8.8 5.5 0.52 10.5 0.4 2.6 2 0 0 2 2 2 0 Virus attachment protein p12 family 7tm_1 PF00001.16 EMC88217.1 - 8.9e-35 120.0 21.9 1.2e-34 119.6 15.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ni_hydr_CYTB PF01292.15 EMC88217.1 - 0.004 16.5 2.9 0.018 14.4 2.0 2.0 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 YtpI PF14007.1 EMC88217.1 - 0.0079 16.0 11.6 0.45 10.4 0.0 4.0 1 1 2 3 3 3 2 YtpI-like protein 60KD_IMP PF02096.15 EMC88217.1 - 0.033 13.8 1.1 0.087 12.4 0.6 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein PgaD PF13994.1 EMC88217.1 - 0.48 9.9 5.3 0.77 9.2 0.5 2.7 1 1 1 2 2 2 0 PgaD-like protein 7tm_1 PF00001.16 EMC88218.1 - 1.2e-33 116.3 13.2 1.2e-33 116.3 9.1 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) OST3_OST6 PF04756.8 EMC88218.1 - 0.41 10.1 8.8 0.34 10.4 0.1 3.3 3 1 0 3 3 3 0 OST3 / OST6 family DUF805 PF05656.9 EMC88218.1 - 0.83 9.4 16.7 0.81 9.5 3.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF805) UPF0104 PF03706.8 EMC88219.1 - 4.3e-05 22.9 4.6 4.3e-05 22.9 3.2 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0104) Claudin_2 PF13903.1 EMC88219.1 - 0.016 14.8 15.0 0.0094 15.6 8.6 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Synaptobrevin PF00957.16 EMC88219.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF4205 PF13898.1 EMC88220.1 - 3.7e-26 91.6 0.0 4e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) FAM194 PF14977.1 EMC88221.1 - 5.8e-60 201.8 0.0 7.1e-60 201.5 0.0 1.1 1 0 0 1 1 1 1 FAM194 protein 7tm_1 PF00001.16 EMC88222.1 - 6.2e-41 140.2 3.4 7.5e-41 139.9 2.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC88222.1 - 4e-05 22.8 0.1 0.00015 20.9 0.1 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 EMC88222.1 - 0.00062 18.9 1.9 0.00082 18.6 1.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 EMC88222.1 - 0.0007 18.9 1.7 0.001 18.3 1.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc Rdx PF10262.4 EMC88223.1 - 1.4e-14 53.8 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family SH3_3 PF08239.6 EMC88224.1 - 0.013 15.7 0.7 7.2 6.8 0.0 2.7 2 1 0 2 2 2 0 Bacterial SH3 domain CK1gamma_C PF12605.3 EMC88225.1 - 9e-31 106.3 4.9 1.4e-30 105.7 3.4 1.2 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase PF00069.20 EMC88225.1 - 1.5e-28 99.6 0.0 2.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88225.1 - 4.7e-11 42.2 0.0 6.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EMC88225.1 - 0.028 13.7 0.0 0.083 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pro_isomerase PF00160.16 EMC88226.1 - 2.5e-41 141.4 0.8 2.9e-41 141.2 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PX PF00787.19 EMC88227.1 - 6e-14 51.7 0.3 7.2e-14 51.5 0.2 1.1 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EMC88228.1 - 5.5e-84 281.1 20.9 5.5e-84 281.1 14.5 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 EMC88228.1 - 1.1e-27 96.0 0.9 3.8e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 PX domain Sorting_nexin PF03700.8 EMC88228.1 - 2e-13 50.5 3.6 5.4e-13 49.1 2.5 1.7 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain BAR_3_WASP_bdg PF10456.4 EMC88228.1 - 0.00021 20.6 3.3 0.018 14.2 2.2 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Glyco_hydro_48 PF02011.10 EMC88228.1 - 0.026 12.6 0.4 0.041 12.0 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 HR1 PF02185.11 EMC88228.1 - 0.043 13.5 4.6 0.61 9.8 0.5 2.9 2 0 0 2 2 2 0 Hr1 repeat Lipase_chap PF03280.9 EMC88228.1 - 0.21 11.0 13.7 0.75 9.2 8.7 2.6 1 1 1 3 3 3 0 Proteobacterial lipase chaperone protein DivIC PF04977.10 EMC88228.1 - 0.3 10.5 6.6 1.5 8.3 1.1 2.9 2 0 0 2 2 2 0 Septum formation initiator FUSC PF04632.7 EMC88228.1 - 0.49 8.7 4.0 0.71 8.2 2.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Arfaptin PF06456.8 EMC88228.1 - 2.1 7.6 12.6 0.061 12.6 2.4 2.4 2 0 0 2 2 2 0 Arfaptin-like domain YgaB PF14182.1 EMC88228.1 - 2.9 8.1 13.0 0.28 11.4 2.0 3.7 3 1 1 4 4 4 0 YgaB-like protein TBPIP PF07106.8 EMC88228.1 - 3.9 7.0 16.7 0.46 10.0 4.1 2.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PAT1 PF09770.4 EMC88229.1 - 2.2e-31 108.9 11.9 1.6e-19 69.6 0.6 2.1 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 C1-set PF07654.10 EMC88230.1 - 2.5e-21 75.4 0.0 3e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 EMC88230.1 - 0.00065 19.5 0.0 0.00088 19.1 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 EMC88230.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC88230.1 - 0.033 14.0 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.20 EMC88230.1 - 0.071 13.2 0.1 0.42 10.7 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin domain DUF4557 PF15101.1 EMC88231.1 - 2.2e-55 187.8 0.0 2.5e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Ribosomal_S17e PF00833.13 EMC88232.1 - 6.8e-63 209.8 0.5 7.7e-63 209.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 RRM_1 PF00076.17 EMC88233.1 - 9.7e-08 31.5 0.0 0.0064 16.0 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC88233.1 - 1e-05 25.4 0.0 3.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.19 EMC88233.1 - 0.38 10.6 7.0 0.77 9.7 4.8 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF3906 PF13046.1 EMC88234.1 - 0.13 11.9 0.1 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) Adaptin_N PF01602.15 EMC88235.1 - 1.1e-62 212.1 2.8 1.2e-62 212.0 1.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMC88235.1 - 0.00091 19.1 0.7 0.68 9.7 0.0 2.5 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMC88235.1 - 0.001 19.2 0.1 0.0099 16.1 0.0 2.2 1 1 1 2 2 2 1 HEAT repeats GRIP PF01465.15 EMC88235.1 - 0.088 12.3 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 GRIP domain 7tm_4 PF13853.1 EMC88236.1 - 1.1e-61 206.7 6.9 1.1e-61 206.7 4.8 2.0 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC88236.1 - 1.9e-29 102.5 9.6 2.5e-29 102.1 6.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC88236.1 - 0.037 13.1 2.3 0.15 11.1 1.6 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Keratin PF02422.11 EMC88237.1 - 1.8e-44 149.7 19.5 2e-44 149.5 13.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC88238.1 - 3e-43 145.7 19.6 3.3e-43 145.6 13.6 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 EMC88239.1 - 1.2e-07 31.5 0.2 1.4e-07 31.3 0.2 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC88239.1 - 0.0019 18.2 0.1 0.002 18.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC88239.1 - 0.0085 15.9 0.0 0.0098 15.7 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain 7tm_4 PF13853.1 EMC88240.1 - 4.2e-37 127.1 13.2 4.2e-37 127.1 9.2 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC88240.1 - 2.7e-26 92.2 25.6 3.4e-26 91.9 17.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4389 PF14333.1 EMC88240.1 - 3.7 7.3 14.5 0.49 10.1 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Keratin PF02422.11 EMC88241.1 - 5.2e-40 135.3 11.8 5.7e-40 135.2 8.2 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 EMC88242.1 - 3.1e-05 23.8 0.0 3.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Keratin PF02422.11 EMC88243.1 - 5.9e-43 144.8 10.8 6.4e-43 144.6 7.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC88244.1 - 1.1e-42 143.9 11.7 1.2e-42 143.8 8.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC88245.1 - 1.7e-42 143.3 12.3 1.9e-42 143.1 8.6 1.0 1 0 0 1 1 1 1 Keratin DUF4211 PF13926.1 EMC88248.1 - 7.8e-32 109.8 3.3 2.5e-31 108.1 2.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4211) DUF4196 PF13846.1 EMC88248.1 - 8e-08 32.5 0.3 8e-08 32.5 0.2 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4196) Myotub-related PF06602.9 EMC88251.1 - 3e-147 490.0 0.1 4e-147 489.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 EMC88251.1 - 3.5e-11 42.4 0.0 7.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 EMC88251.1 - 9.1e-05 21.8 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC88251.1 - 0.0023 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC88251.1 - 0.0051 17.0 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family NYD-SP28_assoc PF14775.1 EMC88251.1 - 0.014 15.0 3.9 0.47 10.1 0.5 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Cep57_CLD PF14073.1 EMC88252.1 - 5.8e-66 221.6 37.6 5.8e-66 221.6 26.1 2.3 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.8 EMC88252.1 - 2.3e-19 69.1 3.6 2.3e-19 69.1 2.5 4.1 2 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.3 EMC88252.1 - 0.00065 19.4 10.2 0.00065 19.4 7.1 4.1 2 2 1 3 3 3 1 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EMC88252.1 - 0.16 11.5 56.6 0.042 13.4 6.2 3.2 2 1 1 3 3 3 0 IncA protein AAA_27 PF13514.1 EMC88252.1 - 5 4.6 38.6 0.12 10.0 3.7 2.4 2 0 0 2 2 2 0 AAA domain DUF3552 PF12072.3 EMC88253.1 - 0.0096 15.1 13.4 0.0096 15.1 9.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Myosin_HC-like PF07058.6 EMC88253.1 - 0.026 13.6 7.5 0.1 11.6 3.2 2.2 2 0 0 2 2 2 0 Myosin II heavy chain-like ATP-synt_B PF00430.13 EMC88253.1 - 0.08 12.7 6.7 0.19 11.5 4.6 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Metal_resist PF13801.1 EMC88253.1 - 2.5 8.0 4.8 22 5.0 0.5 2.4 2 0 0 2 2 2 0 Heavy-metal resistance DUF2614 PF11023.3 EMC88253.1 - 2.9 7.7 8.1 1.6 8.5 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Innate_immun PF12782.2 EMC88253.1 - 2.9 7.0 11.7 5.1 6.2 8.1 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family NicO PF03824.11 EMC88253.1 - 8.1 5.6 10.2 13 5.0 7.1 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein OmpH PF03938.9 EMC88253.1 - 8.3 6.3 16.2 17 5.2 11.1 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PA26 PF04636.8 EMC88254.1 - 4.4e-212 704.6 1.1 5e-212 704.5 0.8 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.15 EMC88254.1 - 0.0011 18.7 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DnaJ-X PF14308.1 EMC88254.1 - 0.015 14.6 1.5 0.027 13.7 1.0 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing Angiomotin_C PF12240.3 EMC88258.1 - 2.3e-93 311.4 33.6 3.7e-93 310.7 11.7 3.4 2 1 0 2 2 2 2 Angiomotin C terminal IncA PF04156.9 EMC88258.1 - 0.32 10.5 0.0 0.32 10.5 0.0 3.8 2 1 0 2 2 2 0 IncA protein NPV_P10 PF05531.7 EMC88258.1 - 0.78 10.0 3.9 0.95 9.7 0.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.1 EMC88258.1 - 3 7.2 43.2 1.7 8.0 21.0 3.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Ank_2 PF12796.2 EMC88260.1 - 7e-45 151.2 10.5 8.6e-22 77.2 0.1 2.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMC88260.1 - 1.9e-34 115.7 4.1 2.6e-13 49.0 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EMC88260.1 - 2.6e-33 113.8 5.3 4.3e-15 55.7 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC88260.1 - 3.9e-25 85.4 2.4 5.6e-07 29.1 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EMC88260.1 - 6.1e-25 86.6 12.2 9.4e-11 41.6 0.2 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) TRAPPC-Trs85 PF12739.2 EMC88260.1 - 0.043 12.4 1.1 0.069 11.7 0.5 1.3 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Mre11_DNA_bind PF04152.9 EMC88261.1 - 1.8e-48 164.6 0.6 1.8e-48 164.6 0.4 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EMC88261.1 - 1.6e-27 96.2 1.3 2.3e-27 95.6 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMC88261.1 - 1.8e-07 31.0 0.0 5.9e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 7tm_1 PF00001.16 EMC88262.1 - 3.3e-59 200.1 24.4 4.5e-59 199.6 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88262.1 - 2.2e-17 63.1 23.4 2.8e-17 62.7 16.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Innexin PF00876.13 EMC88263.1 - 5e-15 55.4 4.3 8.7e-15 54.6 3.0 1.5 1 0 0 1 1 1 1 Innexin DUF3733 PF12534.3 EMC88263.1 - 0.13 11.5 0.2 0.13 11.5 0.1 2.2 3 0 0 3 3 3 0 Leucine-rich repeat containing protein 8 Cu-oxidase_3 PF07732.10 EMC88264.1 - 2e-29 101.6 0.5 3e-10 39.8 0.0 5.1 5 0 0 5 5 5 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC88264.1 - 8.7e-22 77.1 9.8 6.7e-11 41.8 2.7 5.8 6 1 0 6 6 6 3 Multicopper oxidase L6_membrane PF05805.7 EMC88265.1 - 1.2e-57 194.6 13.7 1.4e-57 194.4 9.5 1.0 1 0 0 1 1 1 1 L6 membrane protein V-set PF07686.12 EMC88266.1 - 1.6e-07 31.2 0.2 2.5e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.3 EMC88266.1 - 0.0012 18.7 0.1 0.0019 18.0 0.1 1.3 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 I-set PF07679.11 EMC88266.1 - 0.018 14.8 0.3 0.05 13.4 0.2 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain Herpes_gE PF02480.11 EMC88266.1 - 0.085 11.1 0.2 0.085 11.1 0.1 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1907 PF08925.6 EMC88267.1 - 8.7e-128 425.3 0.0 9.9e-128 425.1 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) TAF1D PF15333.1 EMC88268.1 - 2e-49 168.3 10.1 8.2e-48 163.0 1.9 2.0 1 1 1 2 2 2 2 TATA box-binding protein-associated factor 1D ALMS_motif PF15309.1 EMC88269.1 - 7.5e-21 74.4 19.9 1.1e-20 73.9 13.8 1.2 1 0 0 1 1 1 1 ALMS motif Exonuc_VII_L PF02601.10 EMC88269.1 - 3.4 6.7 10.6 5 6.2 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.8 EMC88270.1 - 0.56 10.0 8.2 0.8 9.5 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4519 PF15012.1 EMC88271.1 - 1.8e-27 95.0 5.7 2e-27 94.8 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.1 EMC88271.1 - 1.8e-05 24.2 0.1 2e-05 24.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 EMC88271.1 - 0.0005 20.0 0.0 0.00052 20.0 0.0 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 EMC88271.1 - 0.00056 20.0 0.0 0.00059 19.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) DUF2232 PF09991.4 EMC88271.1 - 0.0011 18.0 0.0 0.0012 17.9 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) Vma12 PF11712.3 EMC88271.1 - 0.0023 17.6 0.0 0.0024 17.5 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3753 PF12575.3 EMC88271.1 - 0.0076 16.0 0.1 0.0091 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) DUF106 PF01956.11 EMC88271.1 - 0.019 14.4 0.1 0.021 14.3 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 FTCD_C PF04961.7 EMC88271.1 - 0.031 13.7 0.1 0.031 13.7 0.1 1.0 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase CoatB PF10389.4 EMC88271.1 - 0.054 13.3 0.2 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF2077 PF09850.4 EMC88271.1 - 0.056 12.8 0.0 0.062 12.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF3357 PF11837.3 EMC88271.1 - 0.057 13.2 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) RskA PF10099.4 EMC88271.1 - 0.057 13.1 0.0 0.057 13.1 0.0 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2208 PF09973.4 EMC88271.1 - 0.062 12.5 0.0 0.062 12.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) AHSP PF09236.5 EMC88271.1 - 0.064 13.4 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein DUF3290 PF11694.3 EMC88271.1 - 0.086 12.5 0.4 0.11 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) UPF0233 PF06781.7 EMC88271.1 - 0.13 11.8 0.1 0.14 11.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2116 PF09889.4 EMC88271.1 - 1 9.1 3.4 1.5 8.6 2.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Tup_N PF08581.5 EMC88272.1 - 0.03 14.5 9.2 0.03 14.5 6.4 3.2 3 1 0 3 3 3 0 Tup N-terminal Reo_sigmaC PF04582.7 EMC88272.1 - 0.11 11.6 1.3 0.12 11.5 0.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_11 PF13086.1 EMC88272.1 - 0.65 9.5 7.7 0.79 9.2 5.4 1.3 1 0 0 1 1 1 0 AAA domain DUF4250 PF14056.1 EMC88272.1 - 0.76 9.5 6.6 2.4 7.9 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) MotA_ExbB PF01618.11 EMC88272.1 - 3.6 7.1 9.0 0.5 9.9 1.9 2.2 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family Phos_pyr_kin PF08543.7 EMC88272.1 - 4.2 6.4 6.9 5.7 6.0 1.6 2.0 1 1 1 2 2 2 0 Phosphomethylpyrimidine kinase IF-2B PF01008.12 EMC88272.1 - 6.2 5.7 7.1 11 4.8 4.9 1.4 1 1 0 1 1 1 0 Initiation factor 2 subunit family Tup_N PF08581.5 EMC88273.1 - 0.0011 19.0 7.7 0.0011 19.0 5.4 5.0 3 1 1 4 4 4 1 Tup N-terminal H-kinase_dim PF02895.9 EMC88273.1 - 0.69 10.2 14.3 1.6 9.1 1.8 3.0 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Spectrin PF00435.16 EMC88273.1 - 1.9 8.8 27.3 11 6.3 4.7 3.4 1 1 2 3 3 3 0 Spectrin repeat PEARLI-4 PF05278.7 EMC88273.1 - 9 5.5 30.0 0.28 10.5 2.0 3.0 1 1 2 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) YodL PF14191.1 EMC88273.1 - 9.1 6.8 10.5 0.39 11.2 1.7 2.6 2 1 1 3 3 3 0 YodL-like UPAR_LY6 PF00021.16 EMC88274.1 - 1.1e-09 38.5 12.6 1.5e-09 38.1 8.8 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Topoisom_I_N PF02919.10 EMC88275.1 - 1.3e-101 338.4 4.2 1.3e-101 338.4 2.9 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EMC88275.1 - 2.2e-95 318.2 8.9 2.2e-95 318.2 6.2 2.1 1 1 1 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EMC88275.1 - 3.2e-34 116.3 0.2 1.1e-33 114.6 0.1 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Hanta_nucleocap PF00846.13 EMC88275.1 - 0.007 15.1 9.0 0.012 14.2 6.3 1.3 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein MRP-S23 PF10484.4 EMC88275.1 - 0.028 14.3 0.9 0.028 14.3 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 DUF641 PF04859.7 EMC88275.1 - 0.048 13.4 13.0 0.025 14.3 2.0 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PmbA_TldD PF01523.11 EMC88275.1 - 0.55 9.4 4.2 1.1 8.5 2.9 1.4 1 0 0 1 1 1 0 Putative modulator of DNA gyrase FAM194 PF14977.1 EMC88275.1 - 1.1 8.1 5.9 2.7 6.9 4.1 1.6 1 0 0 1 1 1 0 FAM194 protein Atg14 PF10186.4 EMC88275.1 - 2.2 7.1 16.0 0.099 11.5 6.8 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EMC88275.1 - 3.6 5.9 14.8 0.21 9.9 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 EMC88275.1 - 5 4.3 25.8 0.0024 15.3 9.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF4407 PF14362.1 EMC88275.1 - 5.1 5.9 12.0 0.41 9.5 4.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IncA PF04156.9 EMC88275.1 - 9.9 5.6 14.5 1.6 8.2 5.8 2.3 2 0 0 2 2 2 0 IncA protein BRO1 PF03097.13 EMC88276.1 - 1.2e-114 383.0 0.2 1.9e-114 382.3 0.1 1.3 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.11 EMC88276.1 - 1.3e-15 56.8 4.6 2.6e-15 55.8 3.2 1.6 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.19 EMC88276.1 - 3.3e-13 49.6 0.0 6.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC88276.1 - 2.1e-05 24.3 0.0 5.7e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 PDZ domain DUF1669 PF07894.7 EMC88276.1 - 0.00019 20.7 0.1 0.00039 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) Tricorn_PDZ PF14685.1 EMC88276.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Fmp27_WPPW PF10359.4 EMC88276.1 - 0.058 11.7 2.3 0.099 11.0 1.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain bZIP_Maf PF03131.12 EMC88277.1 - 4.8e-34 116.5 12.7 7e-34 115.9 8.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Maf_N PF08383.6 EMC88277.1 - 4e-22 77.4 2.1 8.1e-22 76.4 1.5 1.6 1 0 0 1 1 1 1 Maf N-terminal region CCDC155 PF14662.1 EMC88277.1 - 0.012 15.1 5.6 0.019 14.5 3.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 EMC88277.1 - 0.032 14.2 14.5 0.096 12.6 10.0 1.8 1 1 0 1 1 1 0 bZIP transcription factor Peptidase_S49 PF01343.13 EMC88277.1 - 0.079 12.7 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 DUF1192 PF06698.6 EMC88277.1 - 0.092 12.5 3.2 3.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF342 PF03961.8 EMC88277.1 - 0.097 11.0 3.4 0.13 10.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_2 PF07716.10 EMC88277.1 - 0.16 11.7 11.3 0.12 12.2 6.3 1.9 1 1 1 2 2 2 0 Basic region leucine zipper Lge1 PF11488.3 EMC88277.1 - 0.56 10.4 4.7 3.7 7.7 2.3 2.3 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DivIC PF04977.10 EMC88277.1 - 4.8 6.7 9.2 1.1 8.8 3.6 1.9 1 1 1 2 2 2 0 Septum formation initiator zf-CCCH PF00642.19 EMC88278.1 - 7e-22 76.6 35.1 4.1e-07 29.5 2.7 6.1 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EMC88278.1 - 0.00033 20.0 0.3 0.00033 20.0 0.2 4.1 4 0 0 4 4 4 2 Putative zinc-finger domain CAP_GLY PF01302.20 EMC88279.1 - 1.1e-32 111.5 1.1 8.2e-16 57.4 0.0 2.4 2 0 0 2 2 2 2 CAP-Gly domain UCH PF00443.24 EMC88279.1 - 8.4e-08 31.6 0.6 4.9e-07 29.1 0.4 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC88279.1 - 0.0078 15.6 4.9 0.27 10.6 0.1 2.6 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Hrs_helical PF12210.3 EMC88279.1 - 0.038 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate NAPRTase PF04095.11 EMC88280.1 - 1.2e-14 54.1 0.0 4.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family EF1_GNE PF00736.14 EMC88282.1 - 1.8e-35 120.4 1.4 4.1e-35 119.3 1.0 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EMC88282.1 - 4.3e-12 45.9 7.7 4.3e-12 45.9 5.4 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Striatin PF08232.7 EMC88282.1 - 0.017 15.4 1.2 0.017 15.4 0.9 2.2 2 0 0 2 2 2 0 Striatin family MinC_N PF05209.8 EMC88282.1 - 0.097 12.4 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain HTH_Tnp_Tc5 PF03221.11 EMC88283.1 - 6.3e-14 51.5 0.0 2.1e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EMC88283.1 - 2.1e-07 30.2 0.0 2.5e-06 26.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease P5CR_dimer PF14748.1 EMC88284.1 - 3.1e-15 56.1 0.3 4.6e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Keratin PF02422.11 EMC88286.1 - 3.4e-33 113.4 6.4 4.1e-33 113.2 4.5 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC88287.1 - 3.4e-33 113.5 15.5 2.6e-32 110.6 10.7 1.9 1 1 0 1 1 1 1 Keratin SNF2_N PF00176.18 EMC88288.1 - 3.7e-23 81.7 0.1 3.7e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain AKAP28 PF14469.1 EMC88289.1 - 1.4e-49 166.7 1.7 1.5e-49 166.5 1.2 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor SynMuv_product PF06047.6 EMC88290.1 - 3.3e-53 177.8 2.3 3.3e-53 177.8 1.6 3.0 2 1 1 3 3 3 1 Ras-induced vulval development antagonist MIP-T3 PF10243.4 EMC88290.1 - 0.0013 17.2 44.1 0.0018 16.8 30.6 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 EMC88290.1 - 1.3 7.2 23.9 1.8 6.7 16.5 1.2 1 0 0 1 1 1 0 Transmembrane protein CDC27 PF09507.5 EMC88290.1 - 1.5 7.9 48.5 0.05 12.8 29.3 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF1675 PF07897.6 EMC88290.1 - 6.2 6.6 31.6 0.19 11.5 17.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Peptidase_S64 PF08192.6 EMC88290.1 - 8.7 4.5 17.6 10 4.2 12.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 PAP2 PF01569.16 EMC88291.1 - 4.7e-24 84.4 0.9 7.9e-24 83.7 0.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily BTB PF00651.26 EMC88292.1 - 2.4e-26 91.8 0.6 3.8e-26 91.2 0.4 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC88292.1 - 5.5e-09 35.8 2.8 5.5e-09 35.8 1.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC88292.1 - 6.4e-08 32.4 13.9 0.00027 21.0 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC88292.1 - 9.7e-07 28.7 13.7 0.00045 20.4 0.6 3.1 3 0 0 3 3 2 2 Zinc finger, C2H2 type DUF3342 PF11822.3 EMC88292.1 - 9.9e-07 28.1 0.3 2.2e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-met PF12874.2 EMC88292.1 - 0.00072 19.6 2.5 0.015 15.4 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC88292.1 - 0.00078 19.5 1.0 0.02 15.0 0.0 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding BTB_2 PF02214.17 EMC88292.1 - 0.0058 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3212 PF11486.3 EMC88292.1 - 0.036 13.8 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) Elf1 PF05129.8 EMC88292.1 - 0.042 13.5 0.3 0.15 11.7 0.2 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF1722 PF08349.6 EMC88292.1 - 0.046 13.5 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) zf-H2C2_5 PF13909.1 EMC88292.1 - 0.048 13.9 2.5 0.048 13.9 1.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EMC88292.1 - 0.33 11.0 3.1 7.6 6.7 0.2 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.2 EMC88292.1 - 0.43 10.4 5.1 0.96 9.3 3.5 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-Di19 PF05605.7 EMC88292.1 - 0.51 10.4 5.5 1.3 9.1 3.8 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 EMC88292.1 - 0.63 10.0 6.1 1.4 8.9 0.1 2.9 3 0 0 3 3 2 0 Zinc ribbon domain Archease PF01951.11 EMC88293.1 - 2.6e-47 160.2 0.1 3.5e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) WD40 PF00400.27 EMC88294.1 - 3.8e-40 134.3 11.4 6.4e-09 35.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMC88294.1 - 2.3e-27 94.6 0.6 7.2e-27 93.1 0.4 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EMC88294.1 - 4.8e-05 23.1 0.9 0.014 15.1 0.1 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.7 EMC88294.1 - 0.024 13.6 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein tRNA-synt_1b PF00579.20 EMC88296.1 - 1.7e-74 250.5 0.0 2.2e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.15 EMC88296.1 - 1.9e-32 110.9 0.0 4.5e-32 109.7 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain fn3 PF00041.16 EMC88297.1 - 1.3e-11 44.4 0.1 2.6e-11 43.4 0.0 1.5 2 0 0 2 2 2 1 Fibronectin type III domain UPF0270 PF06794.7 EMC88297.1 - 0.022 14.4 0.5 5 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Interfer-bind PF09294.5 EMC88297.1 - 0.048 13.6 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF1149 PF06619.6 EMC88297.1 - 0.086 12.7 0.4 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) EF-hand_1 PF00036.27 EMC88298.1 - 2.1e-27 92.3 5.8 2.1e-07 29.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC88298.1 - 1.7e-25 88.9 1.3 2.1e-16 59.7 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC88298.1 - 3.2e-24 83.1 2.9 1.2e-07 30.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC88298.1 - 1.1e-22 77.8 0.1 2.6e-06 26.8 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EMC88298.1 - 1.2e-18 66.4 4.0 5e-09 35.6 0.1 3.7 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC88298.1 - 8.6e-08 32.1 0.1 0.00021 21.2 0.0 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC88298.1 - 6.7e-07 28.9 0.7 0.23 11.2 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMC88298.1 - 0.0008 19.0 0.2 2.8 7.6 0.0 3.2 3 0 0 3 3 3 2 EF hand BCLP PF12304.3 EMC88299.1 - 1.2e-57 194.3 9.2 1.4e-57 194.1 6.4 1.0 1 0 0 1 1 1 1 Beta-casein like protein DUF4383 PF14325.1 EMC88299.1 - 0.095 12.7 9.2 1.1 9.3 4.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) DUF4203 PF13886.1 EMC88299.1 - 0.38 10.1 11.2 0.069 12.6 4.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) IBR PF01485.16 EMC88300.1 - 6.6e-21 73.9 40.6 1.4e-12 47.2 12.3 3.3 3 0 0 3 3 3 2 IBR domain ADK PF00406.17 EMC88301.1 - 1.4e-41 141.8 0.0 1.6e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMC88301.1 - 2.4e-07 30.2 0.0 4.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid Orn_Arg_deC_N PF02784.11 EMC88302.1 - 1.1e-59 201.6 0.0 1.4e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EMC88302.1 - 1e-11 44.5 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EMC88302.1 - 0.00011 21.5 0.0 0.00034 19.9 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Ndufs5 PF10200.4 EMC88303.1 - 7.2e-06 25.9 0.2 8.2e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa WD40 PF00400.27 EMC88305.1 - 7.5e-05 22.4 10.2 1.4 8.8 0.4 6.9 8 1 0 8 8 8 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EMC88305.1 - 0.019 14.4 0.7 0.56 9.6 0.0 3.4 4 1 0 4 4 4 0 PQQ-like domain PQQ PF01011.16 EMC88305.1 - 0.021 14.3 0.2 5.8 6.6 0.0 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat Pkinase_Tyr PF07714.12 EMC88306.1 - 4.3e-104 347.1 0.0 5.8e-104 346.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC88306.1 - 3.1e-48 164.2 0.0 4.6e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 EMC88306.1 - 1.3e-37 127.4 0.0 8.9e-15 54.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC88306.1 - 1.7e-29 101.7 0.0 1e-10 41.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC88306.1 - 4.2e-21 74.8 0.2 1.5e-06 28.2 0.0 5.2 5 1 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 EMC88306.1 - 5.6e-20 71.5 0.0 4.1e-06 27.1 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC88306.1 - 1.6e-16 60.1 1.2 0.0017 18.2 0.0 5.6 3 3 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC88306.1 - 0.0028 17.5 1.7 0.97 9.3 0.0 4.2 3 1 1 5 5 5 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC88306.1 - 0.011 15.7 0.0 0.39 10.7 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Kinase-like PF14531.1 EMC88306.1 - 0.069 12.0 0.1 0.22 10.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like DUF1083 PF06452.6 EMC88306.1 - 0.081 12.7 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1083) ATE_C PF04377.10 EMC88307.1 - 5.1e-45 152.6 0.8 1.6e-44 151.0 0.3 2.0 2 1 1 3 3 3 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EMC88307.1 - 1e-21 76.5 1.0 2.7e-21 75.1 0.7 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF956 PF06115.6 EMC88307.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Nse4_C PF08743.5 EMC88308.1 - 2.9e-26 91.3 0.1 6.1e-26 90.2 0.0 1.6 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EMC88308.1 - 1.5e-17 63.1 0.7 3.7e-17 61.9 0.5 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Plant_tran PF04827.9 EMC88308.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein Yae1_N PF09811.4 EMC88309.1 - 3e-09 36.2 42.0 14 5.3 22.8 4.1 2 1 0 2 2 2 1 Essential protein Yae1, N terminal PH PF00169.24 EMC88310.1 - 2.2e-31 108.1 0.1 1e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC88310.1 - 5.2e-13 49.2 1.2 4.9e-07 29.9 0.3 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EMC88310.1 - 1.9e-12 47.0 0.1 1.4e-05 25.0 0.0 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EMC88310.1 - 9.7e-08 31.9 0.0 0.0081 16.0 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 EMC88310.1 - 1.9e-07 31.2 0.3 0.028 14.5 0.1 2.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EMC88310.1 - 3.1e-05 23.7 0.9 0.006 16.4 0.1 2.8 2 2 0 2 2 2 1 PH domain Trypsin_2 PF13365.1 EMC88311.1 - 1.5e-22 79.8 0.3 2.4e-22 79.1 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EMC88311.1 - 1.3e-16 60.8 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EMC88311.1 - 2.4e-10 40.1 2.6 2.5e-10 40.1 0.3 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 EMC88311.1 - 5.2e-10 39.3 0.4 1.5e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 EMC88311.1 - 6.8e-07 28.1 0.2 0.013 13.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.8 EMC88311.1 - 1.4e-05 24.1 0.1 0.063 12.2 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 LSM PF01423.17 EMC88311.1 - 0.005 16.3 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 LSM domain GRASP55_65 PF04495.9 EMC88311.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain ROF PF07073.7 EMC88311.1 - 0.15 12.0 0.1 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) CUB PF00431.15 EMC88312.1 - 2.3e-230 748.6 0.0 1.2e-27 96.1 0.0 8.1 8 0 0 8 8 8 8 CUB domain CUB_2 PF02408.15 EMC88312.1 - 8.7e-19 67.2 0.0 0.3 10.6 0.0 8.5 8 0 0 8 8 8 7 CUB-like domain DUF3750 PF12570.3 EMC88312.1 - 0.28 11.4 0.3 2.4 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3750) SRCR PF00530.13 EMC88313.1 - 4.8e-62 206.4 16.7 1e-33 115.5 5.0 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC88313.1 - 9e-09 35.4 1.0 0.0057 16.8 0.1 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain DUF3027 PF11228.3 EMC88313.1 - 0.041 13.5 3.4 4 7.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) CUB PF00431.15 EMC88314.1 - 8.1e-16 58.0 0.0 1.4e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 CUB domain Zona_pellucida PF00100.18 EMC88314.1 - 8.5e-15 54.8 1.1 8.5e-15 54.8 0.7 1.5 2 0 0 2 2 2 1 Zona pellucida-like domain SRCR PF00530.13 EMC88315.1 - 5.6e-67 222.3 23.4 1.1e-33 115.5 5.1 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC88315.1 - 1.5e-08 34.8 2.0 0.0049 17.0 0.1 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain DUF3027 PF11228.3 EMC88315.1 - 0.036 13.7 3.7 3.5 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) SapB_2 PF03489.12 EMC88315.1 - 1.7 8.7 4.5 49 4.0 0.1 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 2 SRCR PF00530.13 EMC88316.1 - 2.6e-63 210.5 20.4 1.9e-32 111.4 3.3 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC88316.1 - 2.4e-11 43.7 7.2 4.2e-05 23.7 0.9 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR PF00530.13 EMC88317.1 - 3.6e-64 213.2 18.7 5.5e-32 110.0 3.6 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC88317.1 - 1e-09 38.5 5.3 1.8e-05 24.9 0.6 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Peptidase_C25_C PF03785.9 EMC88317.1 - 0.18 11.6 0.0 22 4.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain DUF4506 PF14958.1 EMC88318.1 - 5.1e-28 97.3 0.1 9.4e-28 96.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) KTI12 PF08433.5 EMC88319.1 - 3.9e-16 59.0 2.6 5e-16 58.7 1.8 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EMC88319.1 - 5.1e-05 23.1 0.1 0.0002 21.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain DUF4259 PF14078.1 EMC88319.1 - 0.031 14.7 1.2 0.052 14.0 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) SNAPc19 PF15497.1 EMC88319.1 - 0.44 10.7 4.8 0.58 10.4 0.1 2.4 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 zf-H2C2_2 PF13465.1 EMC88320.1 - 4.8e-13 48.6 43.1 6.3e-07 29.3 2.6 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMC88320.1 - 2.7e-07 30.4 44.7 0.0024 17.9 4.2 5.2 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EMC88320.1 - 2.1e-05 24.6 49.5 0.12 12.7 5.8 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC88320.1 - 4.4 7.8 50.2 0.21 11.9 3.4 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger Acyl-CoA_dh_1 PF00441.19 EMC88321.1 - 1.7e-50 171.0 0.5 4.1e-49 166.5 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC88321.1 - 2.7e-26 92.3 0.1 6.5e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC88321.1 - 7.7e-25 87.6 0.0 1.4e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC88321.1 - 1e-18 66.5 0.0 1.8e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain WD40 PF00400.27 EMC88322.1 - 1.3e-28 97.7 7.3 2.5e-08 33.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat 7tm_1 PF00001.16 EMC88323.1 - 1.5e-41 142.2 15.8 2.1e-41 141.7 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC88323.1 - 8e-06 25.1 16.6 1.4e-05 24.3 9.8 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.3 EMC88323.1 - 5.8e-05 22.7 10.9 8.3e-05 22.2 7.2 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srbc PF10316.4 EMC88323.1 - 0.0058 15.9 15.1 0.0076 15.5 9.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2243 PF10002.4 EMC88323.1 - 0.01 15.6 0.3 0.027 14.2 0.2 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) DUF2516 PF10724.4 EMC88323.1 - 4.5 7.3 12.6 2.5 8.1 3.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2516) Peptidase_M14 PF00246.19 EMC88324.1 - 6.1e-73 245.8 0.1 1.3e-72 244.7 0.1 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.20 EMC88324.1 - 1e-28 99.7 0.1 2.3e-28 98.6 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain CarboxypepD_reg PF13620.1 EMC88324.1 - 4.1e-12 45.9 0.1 9.5e-12 44.8 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMC88324.1 - 0.00018 21.4 0.2 0.00046 20.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) PEGA PF08308.6 EMC88324.1 - 0.047 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 PEGA domain DUF1533 PF07550.6 EMC88324.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) phage_tail_N PF08400.5 EMC88324.1 - 0.14 11.8 0.3 0.36 10.5 0.2 1.7 1 1 0 1 1 1 0 Prophage tail fibre N-terminal Sulfotransfer_1 PF00685.22 EMC88325.1 - 1.2e-15 57.5 0.0 1.4e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC88325.1 - 2.1e-09 38.4 0.4 4e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Sulfotransferase family PVL_ORF50 PF07768.6 EMC88325.1 - 0.11 12.4 0.1 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family Aminotran_3 PF00202.16 EMC88326.1 - 1.1e-114 382.8 0.0 1.3e-114 382.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMC88326.1 - 0.024 13.5 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Hydrolase_like PF13242.1 EMC88327.1 - 3.9e-17 61.7 0.0 1.3e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMC88327.1 - 1.3e-08 34.6 0.0 2.5e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMC88327.1 - 5.8e-05 23.3 0.1 0.00075 19.7 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMC88327.1 - 0.065 13.6 0.1 0.94 9.8 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.1 EMC88329.1 - 1.5e-18 66.8 0.0 1.9e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC88329.1 - 4e-15 56.3 0.0 5.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC88329.1 - 9.9e-10 38.3 0.0 5.1e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC88329.1 - 1.5e-09 37.8 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC88329.1 - 4e-09 36.8 0.0 5.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC88329.1 - 1.1e-08 35.4 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMC88329.1 - 2.3e-07 30.3 0.0 4.5e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMC88329.1 - 1.4e-06 27.7 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EMC88329.1 - 5.2e-06 26.7 0.0 8.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMC88329.1 - 9.2e-05 21.5 0.0 0.00022 20.3 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase TPMT PF05724.6 EMC88329.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 EMC88329.1 - 0.00019 20.6 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMC88329.1 - 0.00066 18.8 0.0 0.00092 18.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EMC88329.1 - 0.0014 19.4 0.0 0.0019 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EMC88329.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.11 EMC88329.1 - 0.019 13.8 0.0 3.3 6.4 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme PCMT PF01135.14 EMC88329.1 - 0.019 14.5 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NNMT_PNMT_TEMT PF01234.12 EMC88329.1 - 0.028 13.3 0.0 4.3 6.2 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family MetW PF07021.7 EMC88329.1 - 0.034 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EMC88329.1 - 0.035 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Cluap1 PF10234.4 EMC88330.1 - 0.0034 16.6 2.4 0.005 16.0 1.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Rabaptin PF03528.10 EMC88330.1 - 0.021 14.7 2.3 0.021 14.7 1.6 1.9 2 0 0 2 2 2 0 Rabaptin KorB PF08535.5 EMC88330.1 - 0.037 14.1 0.5 0.071 13.2 0.3 1.4 1 0 0 1 1 1 0 KorB domain FlxA PF14282.1 EMC88330.1 - 3.1 7.7 11.1 0.12 12.2 3.0 2.2 2 0 0 2 2 2 0 FlxA-like protein OTU PF02338.14 EMC88331.1 - 2.7e-33 115.1 0.0 6.3e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.13 EMC88331.1 - 9.4e-08 31.0 40.1 1.2e-05 24.2 4.3 4.1 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others DZR PF12773.2 EMC88331.1 - 9.8 6.0 21.8 1.3 8.9 4.0 3.1 2 1 1 3 3 3 0 Double zinc ribbon 2-Hacid_dh_C PF02826.14 EMC88332.1 - 3e-55 186.1 0.0 5.2e-55 185.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMC88332.1 - 4.2e-29 100.6 0.1 5.3e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMC88332.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HDNR PF15115.1 EMC88333.1 - 2.7e-12 46.9 0.1 3.1e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function with conserved HDNR motif Linocin_M18 PF04454.7 EMC88334.1 - 0.14 11.0 0.2 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Encapsulating protein for peroxidase TPR_2 PF07719.12 EMC88334.1 - 0.36 10.8 10.5 0.62 10.1 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC88334.1 - 0.94 9.1 9.1 6.2 6.5 0.6 4.3 4 1 1 5 5 5 0 TPR repeat HEM4 PF02602.10 EMC88335.1 - 1.8e-48 164.7 0.0 2.1e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD BCIP PF13862.1 EMC88336.1 - 3.7e-64 215.8 5.5 4.3e-64 215.5 3.8 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DRY_EERY PF09750.4 EMC88336.1 - 0.082 13.0 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Alternative splicing regulator Reprolysin PF01421.14 EMC88337.1 - 2.7e-71 239.3 0.0 2.7e-71 239.3 0.0 1.8 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 EMC88337.1 - 2.5e-34 117.8 3.6 2.5e-34 117.8 2.5 3.2 3 0 0 3 3 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 EMC88337.1 - 5.4e-34 116.8 0.1 9.6e-34 116.0 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 EMC88337.1 - 5.6e-25 87.3 26.3 5.6e-25 87.3 18.2 4.0 3 1 1 4 4 4 1 Disintegrin Reprolysin_5 PF13688.1 EMC88337.1 - 3.2e-21 76.1 0.0 6.8e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMC88337.1 - 1.4e-15 57.7 0.0 2.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMC88337.1 - 1.9e-15 57.5 0.0 4.7e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC88337.1 - 2.7e-15 56.4 0.0 4.5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 EMC88337.1 - 0.0073 15.9 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.4 EMC88337.1 - 0.083 11.7 0.3 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF1025 PF06262.6 EMC88337.1 - 0.21 11.4 0.2 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase DOCK-C2 PF14429.1 EMC88338.1 - 9.2e-57 191.6 0.2 2e-56 190.5 0.1 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EMC88338.1 - 8.2e-40 135.9 0.1 2.1e-39 134.6 0.1 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_9 PF14604.1 EMC88338.1 - 6.4e-11 41.6 0.0 1.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC88338.1 - 7.9e-10 37.9 0.0 1.7e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC88338.1 - 7.8e-07 28.4 0.0 1.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Neuropeptide_S PF14993.1 EMC88339.1 - 1.6e-23 82.1 4.5 1.7e-21 75.6 3.1 2.2 1 1 0 1 1 1 1 Neuropeptide S precursor protein Claudin_2 PF13903.1 EMC88340.1 - 1.3e-13 51.0 14.7 1.8e-13 50.5 10.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Mito_carr PF00153.22 EMC88340.1 - 0.059 13.0 0.2 0.059 13.0 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial carrier protein zf-LITAF-like PF10601.4 EMC88340.1 - 1 9.2 0.0 1 9.2 0.0 3.9 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain FtsX PF02687.16 EMC88340.1 - 4.3 7.1 14.1 0.74 9.5 0.9 2.7 2 1 0 2 2 2 0 FtsX-like permease family Chordopox_G3 PF06129.7 EMC88342.1 - 0.084 13.0 0.1 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Chordopoxvirus G3 protein LIM PF00412.17 EMC88343.1 - 2.4e-10 40.3 0.1 2.9e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 LIM domain RRN7 PF11781.3 EMC88343.1 - 0.13 11.8 1.9 0.2 11.1 1.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Rad50_zn_hook PF04423.9 EMC88343.1 - 2.6 7.5 5.0 1.4 8.4 0.5 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-HC5HC2H PF13771.1 EMC88344.1 - 5.3e-18 64.9 3.3 5.3e-18 64.9 2.3 3.4 3 2 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMC88344.1 - 7.4e-10 38.8 4.1 7.4e-10 38.8 2.8 3.0 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-RING_2 PF13639.1 EMC88344.1 - 1.8e-05 24.4 9.6 1.8e-05 24.4 6.7 4.1 4 1 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 EMC88344.1 - 0.02 14.9 6.7 0.02 14.9 4.7 3.2 2 1 0 3 3 3 0 RING-H2 zinc finger CPSase_L_D2 PF02786.12 EMC88345.1 - 2.1e-86 288.5 0.0 2.8e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EMC88345.1 - 7.8e-36 122.3 0.0 1.4e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EMC88345.1 - 1.6e-13 50.8 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMC88345.1 - 5.2e-09 35.7 0.0 3.1e-08 33.2 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EMC88345.1 - 2.2e-08 33.2 0.0 3.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMC88345.1 - 2.6e-07 30.1 0.0 4.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMC88345.1 - 5.1e-06 26.1 0.0 1.5e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EMC88345.1 - 3.7e-05 23.6 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain SLT_beta PF02258.11 EMC88345.1 - 0.0026 17.5 0.1 0.0092 15.7 0.0 1.8 2 0 0 2 2 2 1 Shiga-like toxin beta subunit ATP-grasp_5 PF13549.1 EMC88345.1 - 0.017 14.3 0.0 0.047 12.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.14 EMC88345.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain UPF0150 PF03681.10 EMC88345.1 - 0.043 13.4 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) WD40 PF00400.27 EMC88348.1 - 1.4e-10 40.6 1.8 0.013 15.4 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Reprolysin PF01421.14 EMC88350.1 - 8.5e-41 139.7 0.7 8.5e-41 139.7 0.5 2.2 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EMC88350.1 - 6.2e-28 97.2 0.0 9.8e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.7 EMC88350.1 - 3.8e-27 94.6 12.7 3.8e-27 94.6 8.8 3.8 3 2 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.18 EMC88350.1 - 3.2e-21 75.3 23.3 3.2e-21 75.3 16.2 4.1 4 0 0 4 4 4 1 Disintegrin Reprolysin_5 PF13688.1 EMC88350.1 - 3.4e-11 43.4 0.5 7.6e-11 42.3 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMC88350.1 - 9.2e-11 42.3 0.0 1.7e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC88350.1 - 3.8e-10 39.6 0.1 6.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC88350.1 - 1.2e-08 35.2 0.4 2e-08 34.4 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 EMC88350.1 - 0.0016 18.5 12.4 0.0016 18.5 8.6 7.8 6 3 0 6 6 6 1 EGF-like domain Peptidase_M10 PF00413.19 EMC88350.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin RNA_pol_Rpb1_R PF05001.8 EMC88351.1 - 1.4 9.1 11.3 5.3 7.4 2.0 3.1 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Pentapeptide_4 PF13599.1 EMC88352.1 - 7.9e-16 57.6 0.0 4.4e-06 26.4 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Lamprin PF06403.6 EMC88352.1 - 3.8e-07 29.9 48.0 0.075 12.7 2.3 5.8 1 1 4 5 5 5 4 Lamprin Pentapeptide_3 PF13576.1 EMC88352.1 - 0.0043 16.9 0.2 1.2 9.1 0.0 3.8 4 1 1 5 5 5 2 Pentapeptide repeats (9 copies) PMG PF05287.7 EMC88352.1 - 2.5 7.8 6.5 11 5.7 0.7 2.7 1 1 0 2 2 2 0 PMG protein Abhydrolase_5 PF12695.2 EMC88353.1 - 1.3e-29 102.7 0.0 2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC88353.1 - 8.6e-15 55.2 0.1 1.3e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC88353.1 - 1.4e-07 31.3 0.0 0.015 14.8 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC88353.1 - 4.2e-07 29.3 0.0 1.5e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EMC88353.1 - 9.3e-05 21.8 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.7 EMC88353.1 - 0.00063 19.5 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DUF818 PF05677.7 EMC88353.1 - 0.00097 17.9 0.1 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 EMC88353.1 - 0.0062 15.9 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EMC88353.1 - 0.007 15.8 0.0 0.03 13.7 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase RNA_ligase PF09414.5 EMC88353.1 - 0.075 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Abhydrolase_4 PF08386.5 EMC88353.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PAS_11 PF14598.1 EMC88354.1 - 1.4e-24 86.1 0.2 8.8e-20 70.7 0.1 3.0 2 1 1 3 3 3 2 PAS domain PAS_3 PF08447.6 EMC88354.1 - 1.2e-23 83.0 0.0 2.3e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EMC88354.1 - 1.6e-23 82.6 0.0 8e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 EMC88354.1 - 7e-15 54.4 1.1 1.6e-14 53.2 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EMC88354.1 - 2e-10 40.9 0.0 6e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EMC88354.1 - 3.5e-05 23.8 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_6 PF08348.6 EMC88354.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 YheO-like PAS domain FAA_hydrolase PF01557.13 EMC88355.1 - 2.9e-51 174.0 0.0 3.8e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMC88355.1 - 9.3e-36 122.0 0.0 2e-35 121.0 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal zf-A20 PF01754.11 EMC88356.1 - 8.2e-13 47.6 7.7 2.1e-12 46.3 5.3 1.8 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 EMC88356.1 - 1.6e-11 43.8 6.0 1.6e-11 43.8 4.2 2.2 3 0 0 3 3 3 1 AN1-like Zinc finger Bcl-2 PF00452.14 EMC88357.1 - 2.2e-25 88.6 0.1 3.7e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family 5-FTHF_cyc-lig PF01812.15 EMC88358.1 - 1.5e-44 151.9 0.0 1.7e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family UPF0258 PF06789.7 EMC88359.1 - 1.6e-78 262.2 1.4 3.5e-78 261.1 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0258) Peptidase_M8 PF01457.11 EMC88360.1 - 0.036 12.4 0.0 0.044 12.1 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin DUF1712 PF08217.6 EMC88360.1 - 0.058 11.6 0.1 0.2 9.8 0.0 1.7 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1712) DUF3312 PF11768.3 EMC88360.1 - 0.1 10.7 0.0 0.15 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) WD40 PF00400.27 EMC88360.1 - 0.12 12.3 0.6 0.31 10.9 0.4 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat ERK-JNK_inhib PF15002.1 EMC88360.1 - 0.13 11.6 0.2 15 4.9 0.0 2.2 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor LVIVD PF08309.6 EMC88360.1 - 0.2 10.6 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 LVIVD repeat Perilipin PF03036.11 EMC88361.1 - 2e-56 191.5 0.3 2.2e-56 191.3 0.2 1.0 1 0 0 1 1 1 1 Perilipin family NPV_P10 PF05531.7 EMC88361.1 - 0.097 12.9 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ras PF00071.17 EMC88362.1 - 3.4e-20 72.0 0.0 4e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88362.1 - 5.9e-12 46.1 0.0 7e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC88362.1 - 0.042 13.1 0.0 0.078 12.2 0.0 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family Kinesin PF00225.18 EMC88363.1 - 1.1e-13 50.5 0.4 3.4e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain NPV_P10 PF05531.7 EMC88363.1 - 0.025 14.7 4.1 0.11 12.7 0.8 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rsd_AlgQ PF04353.8 EMC88363.1 - 0.061 13.0 4.8 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ SPT16 PF08644.6 EMC88363.1 - 0.063 13.1 4.4 0.41 10.4 0.2 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) ADIP PF11559.3 EMC88363.1 - 0.11 12.3 13.9 0.64 9.9 4.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FH2 PF02181.18 EMC88363.1 - 0.17 10.7 6.5 3.3 6.4 2.1 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain TMPIT PF07851.8 EMC88363.1 - 0.24 10.4 5.3 0.74 8.8 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein HemX PF04375.9 EMC88363.1 - 0.3 9.6 10.3 0.23 10.0 3.0 2.1 2 0 0 2 2 2 0 HemX YlqD PF11068.3 EMC88363.1 - 0.31 11.0 14.0 1.4 8.9 3.2 2.3 2 0 0 2 2 2 0 YlqD protein DUF3573 PF12097.3 EMC88363.1 - 0.36 9.3 3.7 3.5 6.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Prominin PF05478.6 EMC88363.1 - 0.37 8.2 3.9 3.3 5.1 0.3 2.1 2 0 0 2 2 2 0 Prominin DUF4559 PF15112.1 EMC88363.1 - 0.77 8.8 13.5 2.3 7.3 5.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4559) CENP-F_leu_zip PF10473.4 EMC88363.1 - 0.82 9.5 20.0 2 8.2 7.3 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapA PF05164.8 EMC88363.1 - 0.98 9.4 8.8 0.57 10.1 1.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapA HOOK PF05622.7 EMC88363.1 - 1.3 6.7 22.6 1.3 6.7 1.9 2.0 1 1 0 2 2 2 0 HOOK protein FlxA PF14282.1 EMC88363.1 - 1.4 8.8 16.6 1.3 9.0 0.2 2.7 2 1 0 2 2 2 0 FlxA-like protein MRP-L28 PF09812.4 EMC88363.1 - 2.5 7.9 8.7 5.2 6.8 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 FemAB PF02388.11 EMC88363.1 - 4.6 5.8 7.4 6.4 5.3 0.1 2.1 2 0 0 2 2 2 0 FemAB family Rho_Binding PF08912.6 EMC88363.1 - 6.7 7.0 12.8 1.8 8.9 2.1 2.8 3 0 0 3 3 2 0 Rho Binding APG6 PF04111.7 EMC88363.1 - 7.2 5.5 18.2 3.6 6.5 8.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2576 PF10845.3 EMC88364.1 - 0.0082 15.2 1.0 0.033 13.3 0.7 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2576) Treslin_N PF15292.1 EMC88366.1 - 8.6e-276 916.9 7.3 9.7e-276 916.7 5.1 1.0 1 0 0 1 1 1 1 Treslin N-terminus DNA_pol_A PF00476.15 EMC88367.1 - 2.3e-127 424.7 0.0 3.2e-127 424.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EMC88367.1 - 0.041 13.3 0.1 0.26 10.7 0.1 2.1 1 1 0 1 1 1 0 3'-5' exonuclease FANCI_S4 PF14678.1 EMC88368.1 - 1.4e-102 342.2 3.9 1.2e-101 339.1 2.3 2.6 2 0 0 2 2 2 1 FANCI solenoid 4 FANCI_HD2 PF14680.1 EMC88368.1 - 5.1e-101 336.6 3.9 5.1e-101 336.6 2.7 2.2 2 0 0 2 2 2 1 FANCI helical domain 2 FANCI_S3 PF14677.1 EMC88368.1 - 1.5e-88 295.8 3.2 1.5e-88 295.8 2.2 3.0 4 0 0 4 4 4 1 FANCI solenoid 3 FANCI_S1 PF14675.1 EMC88368.1 - 4.4e-76 255.1 1.0 1.9e-75 253.0 0.7 2.2 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_S2 PF14676.1 EMC88368.1 - 1.6e-52 177.5 5.2 2.1e-52 177.1 0.1 3.8 4 0 0 4 4 4 1 FANCI solenoid 2 FANCI_HD1 PF14679.1 EMC88368.1 - 3.7e-32 109.8 0.3 1.6e-31 107.8 0.2 2.2 1 0 0 1 1 1 1 FANCI helical domain 1 FANCI_S1-cap PF14674.1 EMC88368.1 - 1.2e-24 86.1 0.8 6.1e-24 83.8 0.5 2.4 1 0 0 1 1 1 1 FANCI solenoid 1 cap CRAL_TRIO PF00650.15 EMC88369.1 - 4.8e-38 130.1 0.0 7.1e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EMC88369.1 - 2.8e-12 46.7 0.0 6e-12 45.6 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC88369.1 - 2.2e-08 34.0 0.6 1.1e-07 31.8 0.4 2.4 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain Abhydrolase_1 PF00561.15 EMC88370.1 - 1.4e-25 90.2 0.0 2e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC88370.1 - 2.6e-09 37.2 0.0 4.1e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC88370.1 - 2.8e-06 27.1 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EMC88370.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Cutinase Ndr PF03096.9 EMC88370.1 - 0.0071 14.8 0.0 0.01 14.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.6 EMC88370.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EMC88370.1 - 0.025 14.1 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) VirJ PF06057.6 EMC88370.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Xlink PF00193.12 EMC88371.1 - 1.4e-51 172.4 0.2 1.4e-30 105.2 0.0 2.5 2 1 0 2 2 2 2 Extracellular link domain V-set PF07686.12 EMC88371.1 - 7e-11 42.0 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC88371.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC88371.1 - 0.00084 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.16 EMC88371.1 - 0.0028 18.2 0.3 0.63 10.7 0.1 2.5 2 0 0 2 2 2 1 Lectin C-type domain Chordopox_A33R PF05966.7 EMC88371.1 - 0.0053 15.5 0.0 0.22 10.2 0.0 2.1 2 0 0 2 2 2 1 Chordopoxvirus A33R protein ig PF00047.20 EMC88371.1 - 0.0058 16.7 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 EMC88371.1 - 0.0063 16.9 0.0 0.061 13.8 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Xlink PF00193.12 EMC88372.1 - 9.1e-142 461.5 17.6 1.8e-37 127.2 0.8 4.9 5 0 0 5 5 5 4 Extracellular link domain Lectin_C PF00059.16 EMC88372.1 - 1.3e-22 80.4 16.5 2.2e-19 70.0 2.1 5.1 5 0 0 5 5 5 3 Lectin C-type domain Sushi PF00084.15 EMC88372.1 - 2.6e-10 40.5 1.8 7e-10 39.1 1.2 1.8 1 0 0 1 1 1 1 Sushi domain (SCR repeat) V-set PF07686.12 EMC88372.1 - 8.8e-09 35.2 0.0 2.6e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain EGF PF00008.22 EMC88372.1 - 0.00029 20.7 4.3 0.00095 19.0 3.0 2.0 1 0 0 1 1 1 1 EGF-like domain Chordopox_A33R PF05966.7 EMC88372.1 - 0.019 13.7 4.8 2.9 6.6 0.1 4.2 4 0 0 4 4 4 0 Chordopoxvirus A33R protein EGF_CA PF07645.10 EMC88372.1 - 0.062 13.3 8.8 0.058 13.4 4.1 2.5 2 1 0 2 2 2 0 Calcium-binding EGF domain RNase_T PF00929.19 EMC88373.1 - 8.7e-30 104.1 0.0 1.3e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EMC88373.1 - 4e-05 23.1 0.0 9.3e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease RNase_H_2 PF13482.1 EMC88373.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily Det1 PF09737.4 EMC88374.1 - 7e-181 601.4 0.6 8.4e-181 601.1 0.4 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 Ribosomal_S11 PF00411.14 EMC88375.1 - 2.2e-29 101.8 1.4 2.5e-29 101.6 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 MRP-L46 PF11788.3 EMC88376.1 - 1.4e-06 28.9 2.8 2.8e-06 27.9 1.9 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EMC88376.1 - 0.071 12.7 0.0 0.41 10.3 0.0 2.0 1 1 0 1 1 1 0 NUDIX domain NUDIX_4 PF14815.1 EMC88376.1 - 0.082 12.3 0.0 9.3 5.7 0.0 2.5 2 0 0 2 2 2 0 NUDIX domain Pkinase_Tyr PF07714.12 EMC88377.1 - 2.4e-91 305.4 0.5 4.8e-89 297.8 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC88377.1 - 4e-47 160.5 0.0 9.9e-47 159.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain I-set PF07679.11 EMC88377.1 - 7.2e-19 67.4 0.0 1.1e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain LRR_8 PF13855.1 EMC88377.1 - 1e-12 47.5 3.8 3.9e-12 45.7 0.7 2.7 2 0 0 2 2 2 1 Leucine rich repeat Ig_2 PF13895.1 EMC88377.1 - 2.1e-12 46.9 0.6 2.2e-06 27.7 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC88377.1 - 4.3e-10 39.5 2.6 1.6e-08 34.5 0.3 3.0 3 0 0 3 3 2 1 Immunoglobulin domain LRR_4 PF12799.2 EMC88377.1 - 2.2e-08 33.5 1.6 6.4e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Ig_3 PF13927.1 EMC88377.1 - 2.4e-06 27.9 5.8 0.00027 21.3 1.3 3.1 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC88377.1 - 1.1e-05 25.2 0.1 0.09 12.6 0.1 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain LRRNT PF01462.13 EMC88377.1 - 0.00015 21.1 1.6 0.00047 19.5 1.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.28 EMC88377.1 - 0.001 18.7 4.3 0.015 15.2 0.1 4.0 4 0 0 4 4 3 1 Leucine Rich Repeat LRR_5 PF13306.1 EMC88377.1 - 0.0054 16.4 0.0 0.016 14.8 0.0 1.8 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) SKG6 PF08693.5 EMC88377.1 - 0.21 10.9 0.4 0.43 9.9 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_7 PF13504.1 EMC88377.1 - 0.31 11.4 0.1 0.31 11.4 0.1 3.4 3 0 0 3 3 2 0 Leucine rich repeat Peptidase_M14 PF00246.19 EMC88378.1 - 1.1e-22 80.9 0.0 2.3e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Neurochondrin PF05536.6 EMC88378.1 - 0.00083 17.7 0.0 0.0016 16.8 0.0 1.3 1 0 0 1 1 1 1 Neurochondrin AstE_AspA PF04952.9 EMC88378.1 - 0.14 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Kelch_1 PF01344.20 EMC88379.1 - 6.7e-53 176.0 0.5 6e-12 44.9 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EMC88379.1 - 4.5e-33 112.0 1.7 7.4e-07 29.0 0.0 6.2 2 2 4 6 6 6 5 Kelch motif BACK PF07707.10 EMC88379.1 - 4.7e-33 113.1 3.3 5.9e-33 112.7 1.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 EMC88379.1 - 2.2e-28 97.7 0.3 1.7e-07 31.1 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB PF00651.26 EMC88379.1 - 2.5e-26 91.8 0.2 5.4e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 EMC88379.1 - 4.5e-25 87.1 1.9 4.1e-09 36.0 0.0 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC88379.1 - 1.1e-23 82.0 4.6 0.00016 21.3 0.0 6.3 5 1 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 EMC88379.1 - 7.6e-17 60.8 0.6 1.1e-08 34.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 EMC88379.1 - 0.0036 16.4 0.0 0.0087 15.2 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) DUF1668 PF07893.8 EMC88379.1 - 0.0061 15.7 0.2 0.03 13.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) Root_cap PF06830.6 EMC88379.1 - 0.045 13.6 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Root cap OATP PF03137.15 EMC88380.1 - 2.3e-189 629.9 2.5 2.8e-189 629.6 1.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EMC88380.1 - 4.9e-26 91.2 9.2 4.9e-26 91.2 6.4 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.10 EMC88380.1 - 8.6e-06 25.5 9.3 9.4e-06 25.4 4.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC88380.1 - 0.0024 17.8 9.0 0.0024 17.8 6.2 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain PUCC PF03209.10 EMC88380.1 - 0.11 11.2 0.1 0.11 11.2 0.1 3.9 4 0 0 4 4 4 0 PUCC protein DUF1180 PF06679.7 EMC88381.1 - 6.3e-21 74.9 0.5 7.2e-21 74.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) SNF2_N PF00176.18 EMC88383.1 - 1.8e-74 250.2 1.0 4.5e-74 248.9 0.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EMC88383.1 - 4.8e-33 112.6 6.7 7.2e-20 70.4 0.0 4.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EMC88383.1 - 2.5e-31 107.8 1.0 2.5e-31 107.8 0.7 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EMC88383.1 - 1.6e-14 53.5 0.0 4.8e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 EMC88383.1 - 0.00098 19.1 0.0 0.13 12.2 0.0 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain RGM_C PF06534.8 EMC88384.1 - 1.4e-74 249.2 0.0 2.2e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.7 EMC88384.1 - 3.2e-68 228.8 1.2 4.6e-68 228.2 0.8 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus C2 PF00168.25 EMC88386.1 - 4.4e-33 112.9 0.1 7e-19 67.4 0.1 2.2 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 EMC88386.1 - 0.014 15.0 0.0 0.1 12.2 0.0 1.9 1 1 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 EMC88386.1 - 0.026 14.0 0.0 0.21 11.0 0.0 2.3 2 1 0 2 2 2 0 CEP76 C2 domain Cadherin PF00028.12 EMC88387.1 - 1e-81 269.2 6.4 1.3e-18 66.9 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 EMC88387.1 - 5.1e-53 179.1 1.2 1.4e-52 177.7 0.8 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 EMC88387.1 - 0.0016 17.9 0.0 12 5.5 0.0 4.4 4 1 0 4 4 4 1 Cadherin-like ASFV_J13L PF05568.6 EMC88387.1 - 0.049 13.1 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF443 PF04276.7 EMC88387.1 - 0.23 10.8 0.3 0.39 10.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF443) He_PIG PF05345.7 EMC88387.1 - 1.2 9.2 4.8 48 4.0 0.1 4.5 4 0 0 4 4 4 0 Putative Ig domain Big_3_4 PF13754.1 EMC88387.1 - 7.1 7.0 12.4 3.3 8.0 0.2 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Lipase_GDSL_2 PF13472.1 EMC88388.1 - 0.0027 17.8 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BASP1 PF05466.7 EMC88391.1 - 2.3e-92 309.0 95.9 2.6e-92 308.9 66.5 1.0 1 0 0 1 1 1 1 Brain acid soluble protein 1 (BASP1 protein) CBM_1 PF00734.13 EMC88392.1 - 7.6e-15 54.2 63.4 0.098 12.3 0.9 11.9 11 0 0 11 11 11 11 Fungal cellulose binding domain TILa PF12714.2 EMC88392.1 - 2.2e-13 49.7 105.5 0.022 14.5 1.9 11.0 7 4 4 11 11 11 11 TILa domain FOLN PF09289.5 EMC88392.1 - 6.3e-08 32.3 92.8 0.13 12.1 0.3 12.7 11 2 1 12 12 12 10 Follistatin/Osteonectin-like EGF domain TILa PF12714.2 EMC88393.1 - 3.3e-15 55.5 111.0 0.023 14.4 1.3 11.0 6 5 5 11 11 11 10 TILa domain FOLN PF09289.5 EMC88393.1 - 2.1e-12 46.6 92.2 0.0024 17.6 2.8 11.5 11 0 0 11 11 11 10 Follistatin/Osteonectin-like EGF domain CBM_1 PF00734.13 EMC88393.1 - 9e-09 34.8 65.7 0.064 12.9 0.6 11.2 10 0 0 10 10 10 9 Fungal cellulose binding domain zf-C3HC4_2 PF13923.1 EMC88394.1 - 3.9e-08 33.1 9.9 3.9e-08 33.1 6.9 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC88394.1 - 4.9e-08 32.5 7.8 1.2e-07 31.2 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC88394.1 - 6.5e-07 29.0 9.7 6.5e-07 29.0 6.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMC88394.1 - 7.1e-07 28.7 9.2 7.1e-07 28.7 6.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC88394.1 - 7.4e-07 28.8 8.7 7.4e-07 28.8 6.0 2.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC88394.1 - 0.0022 18.0 6.0 0.0022 18.0 4.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMC88394.1 - 0.053 13.3 10.2 0.041 13.7 2.9 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PWI PF01480.12 EMC88394.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 PWI domain zf-C3HC4_4 PF15227.1 EMC88394.1 - 0.13 12.1 12.9 0.045 13.6 6.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMC88394.1 - 0.23 11.0 6.5 0.97 9.0 4.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EMC88394.1 - 0.25 11.1 3.9 0.68 9.7 2.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMC88394.1 - 0.66 9.7 7.1 1.7 8.4 4.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EMC88394.1 - 1.6 8.2 10.0 0.73 9.3 0.3 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger SRCR PF00530.13 EMC88395.1 - 3.8e-116 380.0 43.4 4.4e-33 113.5 4.0 4.2 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 EMC88395.1 - 1.7e-14 53.8 19.2 0.0019 18.3 0.5 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain zf-H2C2_2 PF13465.1 EMC88396.1 - 1e-55 183.4 40.3 1.5e-10 40.8 0.7 6.7 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 EMC88396.1 - 1.7e-39 131.7 44.1 8.5e-08 32.1 0.3 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC88396.1 - 2.4e-28 96.3 48.8 7.3e-06 25.9 0.4 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC88396.1 - 5.3e-15 54.7 33.6 0.0012 18.6 0.2 7.3 7 2 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC88396.1 - 7.4e-11 41.8 16.2 0.038 14.1 0.0 6.4 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 EMC88396.1 - 2.7e-05 23.7 14.0 0.054 13.2 0.3 4.6 1 1 3 4 4 4 4 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.7 EMC88396.1 - 0.00022 21.2 26.3 0.65 10.1 2.8 5.1 2 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 EMC88396.1 - 0.00031 20.1 14.3 2.8 7.5 0.0 5.8 6 0 0 6 6 6 1 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EMC88396.1 - 0.00068 19.3 22.5 0.31 10.8 2.3 4.0 1 1 2 3 3 3 3 Double zinc ribbon Zn-ribbon_8 PF09723.5 EMC88396.1 - 0.0009 19.1 29.5 1.1 9.3 0.1 6.2 3 2 2 5 5 5 2 Zinc ribbon domain C1_3 PF07649.7 EMC88396.1 - 0.0014 18.6 17.7 5.2 7.1 0.0 5.8 6 0 0 6 6 6 0 C1-like domain zf-LYAR PF08790.6 EMC88396.1 - 0.005 16.5 15.6 2.1 8.1 0.1 6.5 7 0 0 7 7 7 1 LYAR-type C2HC zinc finger BolA PF01722.13 EMC88396.1 - 0.0067 16.3 3.7 2.7 8.0 0.2 3.6 1 1 1 2 2 2 1 BolA-like protein zf-RING_3 PF14369.1 EMC88396.1 - 0.011 15.7 21.2 0.37 10.8 0.1 5.7 6 0 0 6 6 6 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 EMC88396.1 - 0.011 15.5 1.5 0.011 15.5 1.1 4.8 3 1 0 4 4 4 0 Transposase zinc-ribbon domain CpXC PF14353.1 EMC88396.1 - 0.016 15.1 20.9 1.5 8.7 0.0 5.7 4 1 0 5 5 5 0 CpXC protein C1_4 PF07975.7 EMC88396.1 - 0.016 15.1 17.6 3.5 7.7 0.6 4.8 1 1 4 5 5 5 0 TFIIH C1-like domain zf-HIT PF04438.11 EMC88396.1 - 0.032 13.8 27.1 4.8 6.9 0.1 6.0 6 0 0 6 6 6 0 HIT zinc finger Ogr_Delta PF04606.7 EMC88396.1 - 0.033 13.8 1.1 0.033 13.8 0.7 4.5 4 2 0 4 4 4 0 Ogr/Delta-like zinc finger GAGA PF09237.6 EMC88396.1 - 0.035 13.7 23.5 0.043 13.4 2.0 5.0 2 2 3 5 5 5 0 GAGA factor FYDLN_acid PF09538.5 EMC88396.1 - 0.035 14.6 13.5 3.3 8.3 0.0 5.0 1 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) zf-IS66 PF13005.2 EMC88396.1 - 0.038 13.9 19.5 4.2 7.4 0.0 6.1 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 DUF329 PF03884.9 EMC88396.1 - 0.068 12.7 19.7 5.3 6.6 0.1 6.2 7 0 0 7 7 7 0 Domain of unknown function (DUF329) zf-trcl PF13451.1 EMC88396.1 - 0.074 12.6 27.5 0.044 13.4 3.8 5.3 4 1 1 5 5 5 0 Probable zinc-binding domain XPA_N PF01286.13 EMC88396.1 - 0.11 12.2 14.9 15 5.3 0.0 6.2 7 0 0 7 7 7 0 XPA protein N-terminal HypA PF01155.14 EMC88396.1 - 0.53 10.0 19.0 6.4 6.4 1.9 3.9 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF2256 PF10013.4 EMC88396.1 - 0.85 9.4 0.0 0.85 9.4 0.0 6.5 6 1 1 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.16 EMC88396.1 - 1.1 9.2 28.4 29 4.6 3.5 5.3 1 1 2 3 3 3 0 FYVE zinc finger zf-AN1 PF01428.11 EMC88396.1 - 1.5 8.7 23.3 12 5.8 0.1 6.1 5 1 0 5 5 5 0 AN1-like Zinc finger LIM PF00412.17 EMC88396.1 - 1.9 8.6 17.6 2 8.5 1.3 4.7 3 2 2 5 5 5 0 LIM domain zf-ISL3 PF14690.1 EMC88396.1 - 2.9 8.0 31.1 1.8 8.6 0.4 6.1 4 1 2 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-met PF12874.2 EMC88396.1 - 3.2 8.0 27.7 1.7 8.9 0.2 6.2 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC88396.1 - 3.2 7.9 20.0 9.6 6.3 0.2 5.3 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) PHF5 PF03660.9 EMC88396.1 - 4.5 7.3 8.2 2.6 8.1 1.2 2.4 1 1 2 3 3 3 0 PHF5-like protein COX5B PF01215.14 EMC88396.1 - 5.5 6.6 14.3 4.8 6.8 0.1 4.8 1 1 5 6 6 6 0 Cytochrome c oxidase subunit Vb GF_recep_IV PF14843.1 EMC88396.1 - 6.3 6.4 14.3 6 6.4 3.4 2.4 1 1 0 2 2 2 0 Growth factor receptor domain IV DUF2321 PF10083.4 EMC88396.1 - 6.5 6.2 21.3 4.7 6.6 0.5 4.7 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-CSL PF05207.8 EMC88396.1 - 10 5.7 18.1 34 4.0 0.1 4.6 1 1 4 5 5 5 0 CSL zinc finger Trypsin PF00089.21 EMC88397.1 - 1.9e-42 145.3 0.1 2.1e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC88397.1 - 8.2e-05 22.0 0.2 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC88397.1 - 0.011 15.7 0.1 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain Annexin PF00191.15 EMC88398.1 - 2.5e-67 222.6 9.3 6.6e-24 83.5 0.2 3.9 4 0 0 4 4 4 3 Annexin TPR_8 PF13181.1 EMC88398.1 - 0.084 12.6 0.1 13 5.8 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3186 PF11382.3 EMC88398.1 - 0.11 11.5 2.7 0.24 10.5 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3186) XkdN PF08890.6 EMC88398.1 - 0.27 10.9 2.6 0.35 10.6 0.1 2.3 2 1 0 2 2 2 0 Phage XkdN-like protein Annexin PF00191.15 EMC88399.1 - 9.6e-88 288.0 11.8 4.1e-24 84.2 0.2 4.0 4 0 0 4 4 4 4 Annexin XkdN PF08890.6 EMC88399.1 - 0.0024 17.6 0.5 0.11 12.3 0.1 2.5 2 1 0 2 2 2 1 Phage XkdN-like protein TPR_8 PF13181.1 EMC88399.1 - 0.021 14.5 0.1 20 5.2 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat CPL PF08144.6 EMC88399.1 - 0.039 13.8 0.2 6.4 6.6 0.0 2.8 3 0 0 3 3 3 0 CPL (NUC119) domain TPR_2 PF07719.12 EMC88399.1 - 0.042 13.7 1.6 5.5 7.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3461 PF11944.3 EMC88399.1 - 0.043 13.6 1.2 0.88 9.4 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) DrrA_P4M PF14860.1 EMC88399.1 - 0.066 12.9 1.0 6.4 6.5 0.0 2.9 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF3186 PF11382.3 EMC88399.1 - 0.088 11.9 0.9 0.11 11.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Cep57_MT_bd PF06657.8 EMC88399.1 - 0.29 11.0 2.0 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 zf-A20 PF01754.11 EMC88400.1 - 7.5e-13 47.7 7.7 2.2e-12 46.3 5.3 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 EMC88400.1 - 1.7e-12 46.9 5.9 1.7e-12 46.9 4.1 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger zf-RING_5 PF14634.1 EMC88400.1 - 7.7 6.3 9.4 51 3.7 0.1 2.6 2 0 0 2 2 2 0 zinc-RING finger domain Amidohydro_1 PF01979.15 EMC88401.1 - 6.3e-44 150.9 0.0 7.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMC88401.1 - 3.7e-07 30.4 0.0 0.00017 21.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EMC88401.1 - 5.5e-06 25.8 0.1 0.00087 18.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMC88401.1 - 0.00031 20.4 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase DUF2039 PF10217.4 EMC88402.1 - 1e-24 86.3 11.4 1.1e-24 86.2 7.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.4 EMC88402.1 - 0.024 14.9 6.7 0.024 14.9 4.6 1.8 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Stc1 PF12898.2 EMC88402.1 - 0.03 14.3 7.0 0.062 13.3 5.0 1.4 1 1 0 1 1 1 0 Stc1 domain DUF2256 PF10013.4 EMC88402.1 - 0.18 11.5 0.2 0.18 11.5 0.2 3.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_3 PF13920.1 EMC88402.1 - 0.25 11.0 13.5 6.9 6.4 2.2 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 EMC88402.1 - 0.37 10.7 9.0 0.61 10.0 0.3 2.8 1 1 2 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.9 EMC88402.1 - 0.52 10.0 11.4 2.6 7.7 0.0 3.1 2 1 1 3 3 3 0 Adenylate kinase, active site lid zinc-ribbons_6 PF07191.7 EMC88402.1 - 4.1 7.2 10.1 46 3.8 7.0 2.0 1 1 0 1 1 1 0 zinc-ribbons zf-RING_5 PF14634.1 EMC88402.1 - 5.2 6.8 14.6 5.8 6.7 5.8 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-ribbon_3 PF13248.1 EMC88402.1 - 6.3 6.1 7.7 2.5 7.4 2.0 2.4 2 1 0 2 2 2 0 zinc-ribbon domain Abhydrolase_5 PF12695.2 EMC88403.1 - 3.5e-29 101.4 0.0 4.9e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC88403.1 - 1.7e-15 57.5 0.1 1e-12 48.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC88403.1 - 3.4e-08 33.3 0.0 0.00067 19.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC88403.1 - 1.1e-07 31.2 0.0 1.2e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EMC88403.1 - 3.3e-05 23.2 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.7 EMC88403.1 - 0.0018 18.0 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 EMC88403.1 - 0.0033 16.8 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.7 EMC88403.1 - 0.0038 16.0 0.1 0.0053 15.5 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 EMC88403.1 - 0.012 15.0 0.0 0.068 12.6 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase RNA_ligase PF09414.5 EMC88403.1 - 0.091 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Hydrolase_4 PF12146.3 EMC88403.1 - 0.092 12.6 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase G8 PF10162.4 EMC88404.1 - 2.2e-26 92.0 0.0 4.8e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 G8 domain Ion_trans PF00520.26 EMC88405.1 - 6e-11 41.9 11.8 6e-11 41.9 8.2 1.9 2 1 0 2 2 2 1 Ion transport protein zf-C2H2 PF00096.21 EMC88406.1 - 1.6e-12 47.0 11.8 3.6e-06 26.9 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC88406.1 - 8.2e-11 41.4 11.0 3.6e-05 23.7 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC88406.1 - 2.8e-10 39.9 9.9 3.2e-09 36.6 2.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 EMC88406.1 - 0.0002 21.0 2.5 0.0028 17.3 1.3 2.0 1 1 1 2 2 2 1 BED zinc finger zf-met PF12874.2 EMC88406.1 - 0.00027 21.0 1.3 0.031 14.5 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC88406.1 - 0.0011 18.8 3.6 0.13 12.2 0.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EMC88406.1 - 0.0074 15.7 0.3 0.011 15.2 0.2 1.4 1 1 0 1 1 1 1 Rad50 zinc hook motif zf-TRAF PF02176.13 EMC88406.1 - 0.0094 16.3 1.5 0.012 15.9 1.0 1.1 1 0 0 1 1 1 1 TRAF-type zinc finger zf-Di19 PF05605.7 EMC88406.1 - 0.019 15.0 3.1 0.039 14.0 2.2 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EMC88406.1 - 0.024 14.8 3.1 0.29 11.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC88406.1 - 0.035 14.2 0.9 0.05 13.7 0.6 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EMC88406.1 - 0.044 13.2 0.1 0.049 13.0 0.1 1.1 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS1 PF03811.8 EMC88406.1 - 0.049 13.1 0.9 0.09 12.2 0.6 1.5 1 0 0 1 1 1 0 InsA N-terminal domain Tmpp129 PF10272.4 EMC88406.1 - 0.065 11.9 1.7 0.074 11.7 1.2 1.0 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-Sec23_Sec24 PF04810.10 EMC88406.1 - 0.069 12.7 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.1 EMC88406.1 - 0.085 12.5 2.7 0.68 9.6 0.5 2.2 1 1 1 2 2 2 0 zinc-finger of a C2HC-type DUF2225 PF09986.4 EMC88406.1 - 0.13 11.6 1.0 0.2 11.0 0.2 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Prok-RING_4 PF14447.1 EMC88406.1 - 0.14 11.6 0.8 0.34 10.4 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RRN7 PF11781.3 EMC88406.1 - 0.15 11.5 1.2 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_5 PF13909.1 EMC88406.1 - 4.3 7.7 6.0 12 6.3 0.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain MAM PF00629.18 EMC88407.1 - 6.3e-137 451.8 0.0 2.9e-45 153.9 0.0 4.0 4 0 0 4 4 4 4 MAM domain CBM_4_9 PF02018.12 EMC88407.1 - 0.12 12.4 0.8 2 8.4 0.0 2.8 3 0 0 3 3 3 0 Carbohydrate binding domain GGGtGRT PF14057.1 EMC88409.1 - 3.9 6.1 7.6 12 4.5 0.6 2.7 1 1 2 3 3 3 0 GGGtGRT protein Pkinase_C PF00433.19 EMC88410.1 - 5.6e-10 39.5 2.0 7.5e-10 39.1 1.4 1.2 1 0 0 1 1 1 1 Protein kinase C terminal domain MA3 PF02847.12 EMC88411.1 - 2.6e-12 46.4 0.3 4.3e-12 45.7 0.2 1.4 1 0 0 1 1 1 1 MA3 domain zf-met PF12874.2 EMC88412.1 - 1.2e-29 101.5 24.7 4e-08 33.1 1.4 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC88412.1 - 6e-25 86.7 20.1 2.6e-07 30.5 1.7 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EMC88412.1 - 1.6e-09 37.1 12.2 0.013 15.0 0.0 4.3 4 0 0 4 4 4 4 U1 zinc finger zf-C2H2_2 PF12756.2 EMC88412.1 - 2.3e-09 37.2 11.3 0.11 12.5 0.2 4.2 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EMC88412.1 - 1.6e-07 31.2 6.1 0.088 12.5 0.1 4.2 4 0 0 4 4 4 2 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.7 EMC88412.1 - 0.0026 17.4 11.7 0.28 10.8 0.7 4.2 4 0 0 4 4 4 1 DBF zinc finger Elf1 PF05129.8 EMC88412.1 - 0.062 12.9 6.6 3.9 7.2 0.1 4.0 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like DUF3449 PF11931.3 EMC88412.1 - 0.18 11.2 6.5 5.3 6.4 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2 PF00096.21 EMC88412.1 - 0.47 10.8 15.5 3.9 8.0 1.0 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Eapp_C PF10238.4 EMC88412.1 - 0.66 9.8 11.9 0.11 12.4 3.9 2.7 3 1 0 3 3 3 0 E2F-associated phosphoprotein C1_1 PF00130.17 EMC88412.1 - 0.73 9.6 4.5 17 5.2 0.0 3.8 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_4 PF13894.1 EMC88412.1 - 1.6 9.2 13.0 23 5.6 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger CRAL_TRIO_2 PF13716.1 EMC88413.1 - 9.9e-12 44.9 0.0 2.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.16 EMC88413.1 - 1.2e-05 25.5 21.0 0.00034 20.8 0.3 4.3 3 1 1 4 4 4 2 Spectrin repeat Arch_ATPase PF01637.13 EMC88413.1 - 0.0028 17.3 0.2 0.0054 16.4 0.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase PH PF00169.24 EMC88414.1 - 9.8e-09 35.3 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC88414.1 - 3.6e-06 27.1 0.2 1.6e-05 25.1 0.0 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EMC88414.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 EMC88414.1 - 0.045 13.8 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DNA_pol3_delta2 PF13177.1 EMC88414.1 - 0.051 13.2 0.7 0.079 12.6 0.5 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Cmc1 PF08583.5 EMC88414.1 - 0.13 12.0 2.0 6.3 6.6 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Gasdermin PF04598.7 EMC88415.1 - 2.7e-41 141.8 0.1 3.2e-41 141.5 0.1 1.0 1 0 0 1 1 1 1 Gasdermin family C1_3 PF07649.7 EMC88415.1 - 0.0031 17.4 1.1 0.0031 17.4 0.8 2.1 3 0 0 3 3 3 1 C1-like domain PAP_central PF04928.12 EMC88415.1 - 0.14 10.9 0.0 0.51 9.1 0.0 1.8 2 0 0 2 2 2 0 Poly(A) polymerase central domain Oxysterol_BP PF01237.13 EMC88416.1 - 1.6e-131 438.0 0.6 1.6e-131 438.0 0.4 2.4 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EMC88416.1 - 2.8e-13 49.7 0.4 6.3e-13 48.6 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EMC88416.1 - 0.00018 21.7 0.6 0.013 15.7 0.4 3.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMC88416.1 - 0.00064 19.8 2.8 0.0014 18.7 0.8 2.5 2 1 0 2 2 2 1 PH domain AAA_27 PF13514.1 EMC88416.1 - 0.022 12.4 2.0 2.4 5.7 0.7 2.1 2 0 0 2 2 2 0 AAA domain GAF PF01590.21 EMC88417.1 - 9.5e-43 145.9 0.0 5.3e-24 85.0 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EMC88417.1 - 6.1e-21 74.8 0.0 2.1e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.1 EMC88417.1 - 2e-19 70.5 0.0 5.1e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 GAF domain PDEase_I PF00233.14 EMC88417.1 - 0.016 14.9 2.5 0.026 14.2 0.6 2.0 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase WTX PF09422.5 EMC88418.1 - 4.8e-57 193.9 13.6 4.8e-57 193.9 9.5 3.4 2 1 0 3 3 3 2 WTX protein 7tm_1 PF00001.16 EMC88419.1 - 7.2e-09 35.1 23.5 1.6e-08 33.9 16.2 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88419.1 - 0.0042 16.2 21.8 0.0061 15.7 15.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC88419.1 - 0.64 9.0 24.6 0.15 11.1 9.0 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Kelch_1 PF01344.20 EMC88420.1 - 3.5e-44 148.1 0.2 1.7e-12 46.7 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC88420.1 - 4.9e-35 118.2 0.1 1.6e-07 31.1 0.0 5.8 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 EMC88420.1 - 7.6e-32 109.2 0.3 1.7e-31 108.0 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 EMC88420.1 - 7.9e-28 96.6 5.3 5.7e-27 93.8 1.7 2.5 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 EMC88420.1 - 1.5e-26 91.1 0.8 1.3e-05 24.7 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 EMC88420.1 - 1.3e-17 63.2 0.0 0.029 14.1 0.0 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC88420.1 - 9.6e-16 57.4 0.1 0.013 15.6 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC88420.1 - 6.7e-13 48.2 0.8 0.00041 20.2 0.0 6.0 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.3 EMC88420.1 - 0.00031 20.0 3.8 0.00034 19.8 0.6 2.3 1 1 2 3 3 3 1 Domain of unknown function (DUF3342) Kelch_1 PF01344.20 EMC88421.1 - 8e-44 146.9 16.0 1.1e-13 50.4 0.0 6.0 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 EMC88421.1 - 2.6e-32 110.6 0.6 2.6e-32 110.6 0.4 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 EMC88421.1 - 6.3e-32 108.4 8.9 5.8e-07 29.4 0.0 5.6 2 1 3 5 5 5 5 Kelch motif BTB PF00651.26 EMC88421.1 - 6.7e-29 100.1 1.7 1.4e-28 99.0 0.6 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 EMC88421.1 - 3.8e-23 81.0 3.7 5.6e-05 23.1 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC88421.1 - 7e-21 73.7 4.0 2.9e-05 23.7 0.0 5.9 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC88421.1 - 5.1e-18 64.0 6.0 1e-05 25.0 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EMC88421.1 - 3.4e-08 33.2 9.2 0.088 12.7 0.1 5.6 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.3 EMC88421.1 - 0.0022 17.1 0.8 0.0042 16.2 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) STOP PF05217.7 EMC88422.1 - 0.0015 18.2 0.7 0.0026 17.5 0.5 1.3 1 0 0 1 1 1 1 STOP protein PMP22_Claudin PF00822.15 EMC88423.1 - 1.2e-34 119.4 12.4 1.6e-34 118.9 8.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC88423.1 - 7.9e-09 35.4 14.3 8.4e-09 35.3 8.5 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EMC88423.1 - 6.6e-05 22.2 6.8 0.0087 15.3 0.2 2.2 1 1 0 2 2 2 2 Clc-like DUF996 PF06195.8 EMC88423.1 - 0.21 11.5 3.6 0.21 11.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Amastin PF07344.6 EMC88423.1 - 2.2 7.8 13.3 0.051 13.1 3.1 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein MgtE PF01769.11 EMC88423.1 - 3.4 7.9 7.9 0.29 11.4 0.9 2.2 2 1 0 2 2 2 0 Divalent cation transporter Hydrophob_seed PF14547.1 EMC88424.1 - 0.21 11.5 9.6 0.018 14.9 3.1 1.9 1 1 1 2 2 2 0 Hydrophobic seed protein KOW PF00467.24 EMC88425.1 - 0.046 13.4 0.2 0.18 11.6 0.1 2.1 1 0 0 1 1 1 0 KOW motif Sulfotransfer_1 PF00685.22 EMC88426.1 - 2.2e-31 109.0 0.0 2.6e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 EMC88426.1 - 0.012 15.2 0.0 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family FAA_hydrolase PF01557.13 EMC88428.1 - 1.4e-54 184.8 0.0 1.6e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Lactamase_B PF00753.22 EMC88429.1 - 1.8e-27 96.2 0.4 2.3e-27 95.9 0.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC88429.1 - 8.4e-05 22.1 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC88429.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMC88430.1 - 5.1e-27 94.7 0.3 6.9e-27 94.3 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC88430.1 - 3.6e-07 29.9 0.1 5.6e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC88430.1 - 0.049 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Fe_hyd_lg_C PF02906.9 EMC88431.1 - 7.6e-90 301.0 0.0 1.1e-89 300.4 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 EMC88431.1 - 9.7e-11 41.5 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Mesothelin PF06060.7 EMC88433.1 - 1.9e-123 412.7 0.2 2.3e-123 412.4 0.1 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Mesothelin PF06060.7 EMC88435.1 - 4.5e-10 38.2 0.1 5.1e-10 38.0 0.1 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) PseudoU_synth_2 PF00849.17 EMC88437.1 - 3.4e-24 85.5 0.0 4.8e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Corona_S1 PF01600.11 EMC88437.1 - 0.028 12.7 0.1 0.04 12.2 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein AAA PF00004.24 EMC88438.1 - 5.2e-14 52.5 0.0 8.1e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMC88438.1 - 2.1e-10 40.4 0.0 4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMC88438.1 - 2.6e-08 33.2 0.0 3.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC88438.1 - 1.5e-07 31.5 0.0 7.1e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC88438.1 - 1.2e-06 28.4 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EMC88438.1 - 2.3e-06 26.5 0.0 4.7e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EMC88438.1 - 6.3e-06 27.0 0.2 2.9e-05 24.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EMC88438.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC88438.1 - 0.00015 22.0 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC88438.1 - 0.00019 21.4 0.0 0.068 13.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EMC88438.1 - 0.00022 20.9 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMC88438.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EMC88438.1 - 0.0031 16.6 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EMC88438.1 - 0.0036 16.9 0.0 0.13 11.9 0.0 2.3 1 1 1 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.1 EMC88438.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EMC88438.1 - 0.0072 15.8 0.1 0.12 11.8 0.0 2.1 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EMC88438.1 - 0.0077 15.6 0.2 0.026 13.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMC88438.1 - 0.0078 14.9 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 EMC88438.1 - 0.0085 16.0 0.8 0.049 13.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 EMC88438.1 - 0.0086 15.7 0.3 0.21 11.2 0.0 2.3 1 1 1 2 2 2 1 NTPase RNA_helicase PF00910.17 EMC88438.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EMC88438.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMC88438.1 - 0.013 15.0 0.0 0.03 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EMC88438.1 - 0.016 14.3 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMC88438.1 - 0.016 15.4 0.0 0.044 14.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EMC88438.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMC88438.1 - 0.018 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NAD_binding_1 PF00175.16 EMC88438.1 - 0.036 14.6 0.0 0.93 10.0 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain AAA_2 PF07724.9 EMC88438.1 - 0.073 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Bac_DnaA PF00308.13 EMC88438.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 EMC88438.1 - 0.11 11.9 0.0 1.4 8.3 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EMC88438.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 EMC88438.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain G-gamma PF00631.17 EMC88440.1 - 3.1e-05 23.6 0.0 3.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain LMF1 PF06762.9 EMC88443.1 - 1e-86 291.1 2.5 1.3e-86 290.8 1.7 1.1 1 0 0 1 1 1 1 Lipase maturation factor HMG_box PF00505.14 EMC88444.1 - 2.5e-25 88.5 1.3 4.9e-25 87.5 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.3 EMC88444.1 - 2.3e-22 79.8 0.1 2.3e-22 79.8 0.1 3.6 3 2 0 3 3 3 1 Sox developmental protein N terminal HMG_box_2 PF09011.5 EMC88444.1 - 5.3e-11 42.7 1.3 1e-10 41.8 0.4 1.8 2 0 0 2 2 2 1 HMG-box domain 7tm_1 PF00001.16 EMC88445.1 - 2.9e-68 229.8 26.0 3.8e-68 229.4 18.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88445.1 - 2.1e-14 53.3 22.3 2.6e-14 53.0 15.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC88445.1 - 3e-08 33.1 20.9 4.3e-08 32.6 14.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC88445.1 - 3.4e-06 26.3 21.9 6.2e-06 25.5 15.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Herpes_US9 PF06072.6 EMC88445.1 - 0.067 13.0 5.4 0.049 13.4 1.2 2.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 C1q PF00386.16 EMC88446.1 - 2.4e-33 114.8 1.5 3e-33 114.5 1.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 EMC88446.1 - 4.2e-08 32.5 15.7 6.5e-08 31.9 10.9 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Tektin PF03148.9 EMC88447.1 - 3.7e-146 486.5 32.4 4.2e-146 486.4 22.5 1.0 1 0 0 1 1 1 1 Tektin family tRNA-synt_2 PF00152.15 EMC88447.1 - 0.054 12.2 2.7 0.088 11.5 1.8 1.5 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Baculo_PEP_C PF04513.7 EMC88447.1 - 0.13 12.0 6.7 0.25 11.1 0.2 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SAB PF04382.8 EMC88447.1 - 0.38 10.4 3.9 5.4 6.8 0.2 3.2 3 0 0 3 3 3 0 SAB domain DUF1818 PF08848.6 EMC88447.1 - 0.85 9.6 5.4 0.2 11.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) Fzo_mitofusin PF04799.8 EMC88447.1 - 2.7 7.3 12.2 0.27 10.5 0.4 3.2 2 1 1 3 3 3 0 fzo-like conserved region TMF_DNA_bd PF12329.3 EMC88447.1 - 4.9 7.0 29.3 0.14 11.9 0.6 3.9 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EMC88447.1 - 5.1 6.6 20.8 0.82 9.1 1.5 4.0 4 0 0 4 4 4 0 Septum formation initiator B9-C2 PF07162.6 EMC88448.1 - 4.9e-35 120.7 0.1 5.7e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SH3_1 PF00018.23 EMC88449.1 - 3.2e-30 103.2 0.5 1.1e-16 59.9 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC88449.1 - 2.3e-28 97.4 0.3 5.8e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMC88449.1 - 2.5e-23 81.3 0.1 1.4e-10 40.4 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.19 EMC88449.1 - 3.2e-23 81.3 0.3 4.9e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 EMC88449.1 - 0.00061 19.9 0.1 0.0074 16.4 0.0 2.5 3 0 0 3 3 3 1 Bacterial SH3 domain SSF PF00474.12 EMC88450.1 - 1.9e-134 448.3 25.3 6.1e-134 446.6 17.5 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family Gemini_mov PF01708.11 EMC88450.1 - 0.62 9.6 5.2 4.8 6.8 0.0 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein Pribosyl_synth PF14572.1 EMC88451.1 - 2.2e-101 337.2 1.4 3.6e-101 336.4 1.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMC88451.1 - 2e-38 130.6 1.2 3.5e-38 129.8 0.3 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMC88451.1 - 0.00039 20.1 3.3 0.0036 17.0 1.2 2.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain RelB PF04221.7 EMC88451.1 - 0.025 14.3 0.1 3.7 7.3 0.0 2.7 2 0 0 2 2 2 0 RelB antitoxin UN_NPL4 PF11543.3 EMC88451.1 - 0.03 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 7tm_1 PF00001.16 EMC88452.1 - 1.3e-51 175.2 20.1 1.9e-51 174.6 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Synaptobrevin PF00957.16 EMC88452.1 - 1.6 8.4 4.8 8.2 6.1 0.1 3.0 2 1 1 3 3 3 0 Synaptobrevin SHMT PF00464.14 EMC88453.1 - 7.4e-206 683.1 0.0 8.7e-206 682.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.12 EMC88453.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Folliculin PF11704.3 EMC88454.1 - 1.3e-07 31.3 0.1 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Topoisom_bac PF01131.15 EMC88455.1 - 4.5e-103 345.1 0.0 6.4e-103 344.6 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 EMC88455.1 - 4.2e-35 119.4 19.3 6.1e-19 67.6 3.2 3.4 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.17 EMC88455.1 - 3.1e-17 62.3 0.0 8e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 EMC88455.1 - 4e-12 45.4 1.7 4e-12 45.4 1.2 3.5 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger Mab-21 PF03281.9 EMC88456.1 - 5.9e-21 74.8 0.0 6.3e-19 68.2 0.0 2.1 1 1 0 1 1 1 1 Mab-21 protein Gelsolin PF00626.17 EMC88457.1 - 3.8e-64 212.3 2.4 4.9e-15 54.9 0.0 6.9 6 0 0 6 6 6 6 Gelsolin repeat LRR_4 PF12799.2 EMC88457.1 - 4.1e-34 115.6 54.7 7.9e-09 34.9 3.3 8.4 6 2 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC88457.1 - 5.9e-33 112.4 46.2 2.1e-09 37.0 5.1 6.6 2 2 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EMC88457.1 - 1.3e-16 58.0 51.5 0.0095 15.8 0.2 13.3 13 0 0 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 EMC88457.1 - 5.2e-09 34.8 48.8 0.15 12.3 0.5 11.7 11 0 0 11 11 11 6 Leucine rich repeat LRR_6 PF13516.1 EMC88457.1 - 0.0025 17.6 45.5 0.12 12.4 0.2 10.7 9 2 1 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.1 EMC88457.1 - 0.065 12.7 12.8 1.3 8.6 0.1 3.7 1 1 1 3 3 3 0 Leucine-rich repeat LRR_5 PF13306.1 EMC88457.1 - 0.29 10.8 1.8 7.1 6.3 0.1 2.9 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) 2OG-FeII_Oxy_2 PF13532.1 EMC88458.1 - 5.9e-10 39.2 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ApoO PF09769.4 EMC88458.1 - 0.049 13.3 0.2 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O TGS PF02824.16 EMC88459.1 - 1.8e-23 82.1 0.0 3.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMC88459.1 - 1.1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC88459.1 - 2.6e-10 39.8 0.0 4.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EMC88459.1 - 0.0023 18.4 0.0 0.0067 16.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EMC88459.1 - 0.0073 16.1 0.3 0.76 9.5 0.0 2.3 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 EMC88459.1 - 0.11 11.2 0.8 0.5 9.0 0.0 2.2 1 1 1 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 EMC88459.1 - 0.14 11.5 0.5 7.3 5.9 0.2 2.9 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Vac_ImportDeg PF09783.4 EMC88460.1 - 8.3e-58 194.7 5.2 9.3e-58 194.6 3.6 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Amidase_6 PF12671.2 EMC88460.1 - 0.048 13.7 1.2 0.067 13.2 0.4 1.3 1 1 0 1 1 1 0 Putative amidase domain ATP12 PF07542.6 EMC88461.1 - 3.6e-42 143.1 0.4 5.3e-42 142.6 0.3 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein LRR_4 PF12799.2 EMC88462.1 - 7e-16 57.4 18.4 6.7e-07 28.7 0.6 4.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EMC88462.1 - 1.1e-11 44.6 5.5 2.7e-11 43.3 2.3 2.5 2 1 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 EMC88462.1 - 1.5e-11 43.8 19.0 3.7e-06 26.5 2.6 3.5 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EMC88462.1 - 8.8e-06 25.0 16.7 0.29 11.3 0.1 6.6 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC88462.1 - 0.015 15.3 11.2 26 5.6 0.0 6.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EMC88462.1 - 0.018 15.0 23.0 1 9.6 0.2 6.8 6 1 2 8 8 8 0 Leucine Rich repeat VHS PF00790.14 EMC88463.1 - 8.8e-45 151.8 0.1 2.6e-44 150.2 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EMC88463.1 - 6.6e-35 119.1 2.1 6.2e-34 115.9 2.3 2.0 2 0 0 2 2 2 1 GAT domain ENTH PF01417.15 EMC88463.1 - 0.0094 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 ENTH domain PEMT PF04191.8 EMC88465.1 - 1.2e-31 108.9 5.6 1.2e-31 108.9 3.9 1.9 3 0 0 3 3 3 1 Phospholipid methyltransferase Herpes_UL74 PF07982.7 EMC88465.1 - 0.053 12.1 0.1 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpes UL74 glycoproteins ICMT PF04140.9 EMC88465.1 - 0.1 12.7 0.2 0.27 11.4 0.1 1.8 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ras PF00071.17 EMC88466.1 - 1.7e-37 128.2 0.0 2.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88466.1 - 5e-16 59.2 0.0 1.4e-15 57.7 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC88466.1 - 2.3e-07 30.2 0.0 4.5e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC88466.1 - 4.6e-06 26.1 0.0 2.4e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC88466.1 - 0.0069 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EMC88466.1 - 0.013 15.2 0.1 0.077 12.6 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 EMC88466.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EMC88466.1 - 0.094 12.8 0.0 5 7.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain Adenyl_transf PF04439.7 EMC88466.1 - 0.099 11.6 0.1 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Streptomycin adenylyltransferase HSP70 PF00012.15 EMC88466.1 - 0.14 10.0 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Med9 PF07544.8 EMC88467.1 - 6.5e-21 73.8 1.9 6.9e-21 73.7 1.3 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 EMC88467.1 - 1e-07 32.0 2.2 1.2e-07 31.7 1.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex PHA_synth_III_E PF09712.5 EMC88467.1 - 0.0064 15.9 0.9 0.0064 15.9 0.6 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) MinC_N PF05209.8 EMC88467.1 - 0.0068 16.1 0.3 0.0085 15.8 0.2 1.1 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain 4HB_MCP_1 PF12729.2 EMC88467.1 - 0.0088 15.4 0.1 0.01 15.2 0.1 1.1 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction DUF3452 PF11934.3 EMC88467.1 - 0.0093 15.2 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) DASH_Duo1 PF08651.5 EMC88467.1 - 0.012 15.2 0.2 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 TBPIP PF07106.8 EMC88467.1 - 0.014 14.9 2.1 0.018 14.6 1.4 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PilJ PF13675.1 EMC88467.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Seryl_tRNA_N PF02403.17 EMC88467.1 - 0.021 14.8 0.6 0.025 14.6 0.4 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ELK PF03789.8 EMC88467.1 - 0.022 14.5 1.8 0.17 11.7 0.3 2.3 2 0 0 2 2 2 0 ELK domain DUF342 PF03961.8 EMC88467.1 - 0.025 12.9 1.8 0.031 12.6 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CHASE3 PF05227.8 EMC88467.1 - 0.029 14.0 0.5 0.037 13.7 0.3 1.1 1 0 0 1 1 1 0 CHASE3 domain GrpE PF01025.14 EMC88467.1 - 0.033 13.7 0.2 0.037 13.5 0.2 1.1 1 0 0 1 1 1 0 GrpE IncA PF04156.9 EMC88467.1 - 0.043 13.4 3.4 0.051 13.1 2.3 1.1 1 0 0 1 1 1 0 IncA protein HAP1_N PF04849.8 EMC88467.1 - 0.06 12.2 4.9 0.14 11.1 3.4 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region SRP_SPB PF02978.14 EMC88467.1 - 0.076 13.2 1.3 0.11 12.7 0.9 1.4 1 1 0 1 1 1 0 Signal peptide binding domain BSD PF03909.12 EMC88467.1 - 0.085 12.6 0.6 0.87 9.3 0.2 2.1 2 0 0 2 2 2 0 BSD domain UvrD-helicase PF00580.16 EMC88467.1 - 0.086 12.1 0.6 0.094 11.9 0.4 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Myb_DNA-bind_4 PF13837.1 EMC88467.1 - 0.089 12.9 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Fib_alpha PF08702.5 EMC88467.1 - 0.09 12.9 4.6 0.16 12.0 3.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF964 PF06133.6 EMC88467.1 - 0.092 12.7 3.2 0.13 12.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF964) zf-CpG_bind_C PF12269.3 EMC88467.1 - 0.095 12.1 0.5 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF4047 PF13256.1 EMC88467.1 - 0.11 12.4 0.6 0.15 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) COG6 PF06419.6 EMC88467.1 - 0.11 10.5 2.3 0.13 10.3 1.6 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 HSBP1 PF06825.7 EMC88467.1 - 0.13 11.8 0.4 0.13 11.8 0.3 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF2232 PF09991.4 EMC88467.1 - 0.13 11.1 0.6 0.14 11.1 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) KSR1-SAM PF13543.1 EMC88467.1 - 0.16 11.7 2.5 1.7 8.4 0.0 2.0 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Enkurin PF13864.1 EMC88467.1 - 0.18 12.0 5.6 2.7 8.2 0.0 2.0 1 1 1 2 2 2 0 Calmodulin-binding XPC-binding PF09280.6 EMC88467.1 - 0.19 11.2 6.3 4.8 6.7 0.0 2.4 2 1 0 2 2 2 0 XPC-binding domain Med30 PF11315.3 EMC88467.1 - 0.28 11.2 6.8 5.1 7.2 4.7 1.9 1 1 1 2 2 2 0 Mediator complex subunit 30 FlaC_arch PF05377.6 EMC88467.1 - 0.36 10.7 2.1 2 8.3 0.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 EMC88467.1 - 0.48 9.8 3.7 0.73 9.2 2.5 1.2 1 1 0 1 1 1 0 Phage minor structural protein GP20 WXG100 PF06013.7 EMC88467.1 - 0.6 10.1 3.2 6.6 6.8 2.2 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG SlyX PF04102.7 EMC88467.1 - 0.83 10.0 4.5 4.4 7.7 1.3 2.0 2 0 0 2 2 2 0 SlyX MitMem_reg PF13012.1 EMC88467.1 - 2.7 8.1 5.7 4.8 7.2 1.3 2.0 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function FliJ PF02050.11 EMC88467.1 - 5.4 7.0 9.2 18 5.3 6.4 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein DUF897 PF05982.7 EMC88468.1 - 1.4 7.6 4.5 1.3 7.7 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF897) NT5C PF06941.7 EMC88469.1 - 1.3e-78 262.9 0.0 1.5e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) PCI PF01399.22 EMC88470.1 - 5.2e-19 68.5 1.5 1.1e-18 67.5 0.1 2.1 2 0 0 2 2 2 1 PCI domain YjfB_motility PF14070.1 EMC88470.1 - 0.0031 17.2 0.1 0.014 15.2 0.1 2.1 1 0 0 1 1 1 1 Putative motility protein TPR_8 PF13181.1 EMC88470.1 - 0.0048 16.5 1.9 0.048 13.4 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC88470.1 - 0.0071 15.9 2.5 0.015 14.8 0.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC88470.1 - 0.017 15.0 0.9 0.28 11.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC88470.1 - 0.071 13.0 2.3 0.16 11.9 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC88470.1 - 0.48 10.1 2.7 1.6 8.4 0.3 2.6 3 0 0 3 3 3 0 TPR repeat Folliculin PF11704.3 EMC88471.1 - 8.6e-56 188.1 0.0 1.4e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PH PF00169.24 EMC88473.1 - 1.4e-19 70.1 0.3 3.7e-17 62.4 0.1 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC88473.1 - 3.9e-05 23.8 11.0 0.00038 20.6 1.2 4.8 4 2 1 5 5 5 2 Pleckstrin homology domain Baculo_PEP_C PF04513.7 EMC88473.1 - 6.2 6.6 14.0 1 9.1 4.9 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACI-CRD2 PF09305.5 EMC88474.1 - 4.5e-15 55.1 21.7 3.6e-14 52.2 5.1 3.3 3 1 1 4 4 4 2 TACI, cysteine-rich domain BCMA-Tall_bind PF09257.5 EMC88474.1 - 0.32 10.9 26.1 0.12 12.3 4.8 3.2 3 0 0 3 3 3 0 BCMA, TALL-1 binding UCH PF00443.24 EMC88475.1 - 2.9e-64 216.7 0.2 3.6e-64 216.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC88475.1 - 4.2e-29 101.9 0.1 5.6e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EMC88475.1 - 0.094 11.9 11.4 0.12 11.6 0.2 3.4 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3795 PF12675.2 EMC88475.1 - 7.5 6.8 14.2 6.4 7.0 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3795) PAT1 PF09770.4 EMC88476.1 - 2.7 6.1 19.4 3.1 5.9 13.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 EMC88477.1 - 8.7e-30 103.8 0.1 1.4e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC88477.1 - 1.7e-15 57.4 0.2 2.3e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC88477.1 - 2.3e-12 46.9 0.3 3.5e-12 46.3 0.0 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMC88477.1 - 3.9e-06 26.9 0.1 1.2e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMC88477.1 - 1.1e-05 24.7 0.0 0.00012 21.3 0.0 2.1 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EMC88477.1 - 0.0043 16.0 0.1 0.0064 15.4 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EMC88477.1 - 0.014 15.2 0.1 0.035 13.9 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 EMC88477.1 - 0.027 13.8 0.3 0.081 12.3 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMC88477.1 - 0.062 12.3 0.7 2.4 7.2 0.0 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Nitro_FeMo-Co PF02579.12 EMC88477.1 - 0.22 11.6 1.1 0.54 10.3 0.1 2.0 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Mito_morph_reg PF14972.1 EMC88478.1 - 3.1e-80 267.3 0.4 4e-80 267.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator Pkinase PF00069.20 EMC88479.1 - 3.3e-54 183.7 0.0 3.9e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88479.1 - 6.2e-39 133.6 0.0 7.8e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC88479.1 - 1.8e-08 33.7 0.0 3.9e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMC88479.1 - 0.0031 16.4 0.2 0.0048 15.7 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EMC88479.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC88479.1 - 0.04 13.4 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EMC88479.1 - 0.081 12.2 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family IRK PF01007.15 EMC88480.1 - 4.8e-171 568.0 0.1 5.8e-171 567.8 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.5 EMC88480.1 - 2.4e-28 97.7 0.3 4.3e-28 96.9 0.2 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.11 EMC88480.1 - 0.038 13.6 7.1 0.11 12.1 4.9 1.8 1 1 0 1 1 1 0 Ion channel G10 PF01125.12 EMC88482.1 - 8.6e-66 219.9 5.1 9.5e-66 219.8 3.5 1.0 1 0 0 1 1 1 1 G10 protein Metallothio_11 PF02066.10 EMC88482.1 - 2.5 8.0 9.6 0.33 10.8 3.8 1.6 1 1 1 2 2 2 0 Metallothionein family 11 PP28 PF10252.4 EMC88483.1 - 3.6e-32 110.2 17.5 3.6e-32 110.2 12.1 2.4 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 WD40 PF00400.27 EMC88484.1 - 1.2e-21 75.6 20.9 1.4e-08 34.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EMC88484.1 - 4.8e-05 23.1 0.9 0.19 11.3 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 EMC88484.1 - 0.00013 21.3 1.2 0.019 14.1 0.1 2.4 2 0 0 2 2 2 2 Cortical protein marker for cell polarity Apc4_WD40 PF12894.2 EMC88484.1 - 0.049 13.1 0.1 11 5.5 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EMC88485.1 - 4.2e-18 64.4 19.9 3.6e-07 29.8 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EMC88485.1 - 7.5e-06 25.3 0.2 0.00046 19.5 0.0 2.6 3 0 0 3 3 3 2 Cortical protein marker for cell polarity HECT PF00632.20 EMC88486.1 - 5.4e-101 337.8 0.0 7.1e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMC88486.1 - 5.3e-18 64.5 4.0 1.1e-09 37.9 0.1 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.25 EMC88486.1 - 2.2e-14 53.0 0.1 4.3e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Actin PF00022.14 EMC88488.1 - 2.6e-162 539.7 0.0 2.9e-162 539.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EMC88488.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) F-box PF00646.28 EMC88490.1 - 7e-07 28.7 1.7 7e-07 28.7 1.2 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMC88490.1 - 7.2e-07 28.8 1.0 7.2e-07 28.8 0.7 2.8 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.2 EMC88490.1 - 0.0005 19.6 11.9 0.44 10.2 0.1 6.2 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC88490.1 - 8.1 6.8 28.5 5.7 7.3 0.4 7.2 8 1 0 8 8 8 0 Leucine Rich repeat Nucleoside_tran PF01733.13 EMC88492.1 - 5.8e-51 173.4 2.1 5.8e-51 173.4 1.4 2.0 2 1 0 2 2 2 1 Nucleoside transporter DUF485 PF04341.7 EMC88492.1 - 5 6.9 17.4 2 8.1 0.1 4.7 3 1 1 4 4 4 0 Protein of unknown function, DUF485 WD40 PF00400.27 EMC88493.1 - 6.2e-07 29.0 0.2 0.1 12.5 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat HlyIII PF03006.15 EMC88494.1 - 9.8e-46 155.9 19.8 1.1e-45 155.7 13.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related DIL PF01843.14 EMC88495.1 - 9.2e-23 80.1 0.2 1.8e-22 79.2 0.2 1.5 1 0 0 1 1 1 1 DIL domain RA PF00788.18 EMC88495.1 - 2e-17 63.4 0.0 3.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 EMC88495.1 - 4.1e-11 42.8 0.0 7.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC88495.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SPG48 PF14764.1 EMC88496.1 - 4.1e-176 586.0 15.2 4.1e-176 586.0 10.5 1.5 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking Fork_head PF00250.13 EMC88496.1 - 4.7e-41 138.7 0.3 9e-41 137.8 0.2 1.5 1 0 0 1 1 1 1 Fork head domain UNC45-central PF11701.3 EMC88496.1 - 0.062 12.9 0.6 1.2 8.7 0.0 2.9 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central p450 PF00067.17 EMC88497.1 - 5.2e-121 404.3 0.2 6e-121 404.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC88498.1 - 9.5e-119 396.9 0.2 1.1e-118 396.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 CARD PF00619.16 EMC88499.1 - 3.7e-21 74.7 0.0 1.2e-20 73.1 0.0 2.0 1 0 0 1 1 1 1 Caspase recruitment domain PDZ PF00595.19 EMC88499.1 - 3.3e-06 27.1 0.0 8.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 EMC88499.1 - 0.00074 18.9 7.1 0.0014 18.1 0.0 2.7 2 0 0 2 2 2 1 Guanylate kinase Striatin PF08232.7 EMC88499.1 - 7.3 6.9 46.1 2.6 8.3 7.5 4.3 1 1 1 3 3 3 0 Striatin family Peptidase_M54 PF07998.6 EMC88500.1 - 6.6e-05 22.7 1.5 0.00074 19.3 2.3 1.8 2 0 0 2 2 2 1 Peptidase family M54 Peptidase_M10 PF00413.19 EMC88500.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin HEAT_2 PF13646.1 EMC88501.1 - 1.7e-08 34.6 0.0 1.5e-05 25.2 0.0 4.2 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EMC88501.1 - 2.1e-06 27.3 10.9 0.0085 16.0 0.0 5.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EMC88501.1 - 0.00071 19.9 8.8 0.0038 17.6 0.0 5.0 6 0 0 6 6 6 1 HEAT-like repeat DUF2435 PF10363.4 EMC88501.1 - 0.0065 16.3 0.0 0.048 13.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EMC88501.1 - 0.024 14.6 0.0 1.9 8.5 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion IQ PF00612.22 EMC88502.1 - 3.8e-13 47.7 2.1 0.00012 21.3 0.0 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif SlyX PF04102.7 EMC88502.1 - 0.053 13.9 0.3 0.053 13.9 0.2 7.1 6 2 1 7 7 7 0 SlyX Tropomyosin_1 PF12718.2 EMC88502.1 - 1.6 8.5 59.0 1.3 8.9 2.8 3.6 2 1 1 3 3 3 0 Tropomyosin like APG6 PF04111.7 EMC88502.1 - 3 6.8 45.2 1.4 7.9 8.4 3.5 2 1 1 3 3 3 0 Autophagy protein Apg6 FliE PF02049.13 EMC88502.1 - 7.2 6.7 9.0 3.3 7.8 0.3 3.2 2 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Gal-bind_lectin PF00337.17 EMC88503.1 - 7e-31 106.3 1.0 1.6e-19 69.5 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin 7tm_1 PF00001.16 EMC88504.1 - 5.9e-47 159.9 17.2 7.9e-47 159.5 11.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC88504.1 - 0.0065 15.6 18.0 0.02 14.0 12.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 EMC88504.1 - 0.015 15.1 3.4 0.015 15.1 2.4 3.0 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa DUF1426 PF07234.6 EMC88504.1 - 0.12 12.0 2.7 0.15 11.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1426) Git3 PF11710.3 EMC88504.1 - 2.9 7.4 16.2 0.077 12.5 6.7 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Sulfotransfer_2 PF03567.9 EMC88505.1 - 1.1e-63 215.2 1.8 1.7e-63 214.7 1.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family eIF2A PF08662.6 EMC88506.1 - 7.5e-73 244.3 8.2 4.6e-67 225.5 1.7 4.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EMC88506.1 - 1.3e-06 27.9 0.1 3.2e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC88506.1 - 5e-05 23.0 0.1 0.00015 21.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.7 EMC88506.1 - 0.0012 16.7 0.3 0.39 8.4 0.1 2.4 1 1 0 2 2 2 2 IKI3 family WD40 PF00400.27 EMC88506.1 - 0.004 17.0 4.0 28 4.8 0.0 5.7 7 0 0 7 7 7 0 WD domain, G-beta repeat RRM_6 PF14259.1 EMC88506.1 - 0.0072 16.2 0.1 0.036 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EMC88506.1 - 0.075 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PX PF00787.19 EMC88507.1 - 1.8e-21 76.0 2.1 1.8e-21 76.0 1.5 2.0 2 0 0 2 2 2 1 PX domain EPSP_synthase PF00275.15 EMC88507.1 - 0.098 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TMPIT PF07851.8 EMC88507.1 - 0.48 9.4 6.0 0.25 10.3 2.7 1.5 2 0 0 2 2 2 0 TMPIT-like protein NUDIX PF00293.23 EMC88508.1 - 2.5e-17 62.7 0.0 3.3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EMC88508.1 - 0.013 14.9 0.1 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain FtsJ PF01728.14 EMC88509.1 - 5.6e-52 176.3 0.0 6.8e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EMC88509.1 - 0.03 14.0 0.0 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MAD PF05557.8 EMC88510.1 - 7.1e-239 794.6 100.1 8e-239 794.4 69.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.13 EMC88510.1 - 0.0014 18.5 6.3 0.0014 18.5 4.3 10.4 7 3 4 11 11 11 1 TSC-22/dip/bun family AhpC-TSA PF00578.16 EMC88510.1 - 0.025 14.2 1.8 2.9 7.5 0.0 3.2 3 0 0 3 3 3 0 AhpC/TSA family PRK PF00485.13 EMC88510.1 - 4.3 6.8 9.6 0.34 10.4 1.1 2.7 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family LRR_8 PF13855.1 EMC88511.1 - 2.5e-23 81.5 5.8 3.7e-14 52.2 0.2 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC88511.1 - 3.8e-12 45.5 10.0 7.9e-05 22.1 0.3 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC88511.1 - 9.4e-08 31.8 0.2 2e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC88511.1 - 3.7e-07 29.2 8.1 1 9.6 0.0 5.6 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.1 EMC88511.1 - 0.00058 19.6 7.8 10 6.5 0.1 5.5 4 1 0 4 4 4 1 Leucine Rich repeat MSC PF09402.5 EMC88511.1 - 0.0007 18.4 1.8 0.0024 16.6 0.2 2.1 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain FixQ PF05545.6 EMC88511.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ LRR_7 PF13504.1 EMC88511.1 - 1.6 9.2 5.9 34 5.2 0.2 4.5 5 0 0 5 5 5 0 Leucine rich repeat DUF2372 PF10178.4 EMC88512.1 - 2.3e-31 107.7 0.1 3e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Solute_trans_a PF03619.11 EMC88513.1 - 8.6e-98 326.9 20.9 1.1e-97 326.6 14.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1642 PF07852.6 EMC88513.1 - 0.096 13.0 0.1 0.21 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) bZIP_Maf PF03131.12 EMC88514.1 - 1.1e-34 118.5 12.5 1.4e-34 118.2 8.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 EMC88514.1 - 0.00019 20.8 5.4 0.00019 20.8 3.7 2.2 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 EMC88514.1 - 0.0061 16.4 16.7 0.14 12.1 11.5 2.4 1 1 0 1 1 1 1 bZIP transcription factor Spc24 PF08286.6 EMC88514.1 - 0.012 15.2 0.4 0.012 15.2 0.3 1.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1192 PF06698.6 EMC88514.1 - 0.018 14.8 8.2 0.048 13.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2046 PF09755.4 EMC88514.1 - 0.019 13.8 6.2 0.028 13.3 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF972 PF06156.8 EMC88514.1 - 0.034 14.4 2.2 0.034 14.4 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tox-ODYAM1 PF15642.1 EMC88514.1 - 0.041 12.5 2.1 0.048 12.3 1.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus HGTP_anticodon2 PF12745.2 EMC88514.1 - 0.067 12.3 3.9 0.075 12.1 2.7 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Mnd1 PF03962.10 EMC88514.1 - 0.081 12.5 2.4 0.11 12.1 1.7 1.3 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 EMC88514.1 - 0.082 11.3 2.6 0.087 11.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EMC88514.1 - 0.16 10.9 6.4 0.2 10.6 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EMC88514.1 - 0.23 11.3 15.9 0.24 11.2 9.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF4164 PF13747.1 EMC88514.1 - 0.42 10.7 8.4 0.096 12.8 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Uds1 PF15456.1 EMC88514.1 - 0.48 10.4 8.0 1.3 9.0 1.0 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Microtub_assoc PF07989.6 EMC88514.1 - 0.6 9.9 8.3 1.8 8.4 5.8 1.8 1 1 0 1 1 1 0 Microtubule associated IncA PF04156.9 EMC88514.1 - 0.97 8.9 9.8 3.7 7.1 6.8 1.8 1 1 0 1 1 1 0 IncA protein Mst1_SARAH PF11629.3 EMC88514.1 - 1.3 8.9 6.1 14 5.6 0.1 2.7 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 HALZ PF02183.13 EMC88514.1 - 1.9 8.2 9.1 0.94 9.2 3.3 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 EMC88514.1 - 5.9 7.2 12.2 29 5.0 8.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 EMC88514.1 - 6.4 7.2 9.3 5.6 7.4 3.0 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) XkdW PF09636.5 EMC88514.1 - 7.1 6.5 6.4 5.1 7.0 1.7 2.1 1 1 1 2 2 2 0 XkdW protein Glyco_hydro_31 PF01055.21 EMC88515.1 - 1.8e-171 570.8 0.0 2.3e-171 570.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Trefoil PF00088.13 EMC88515.1 - 5e-15 54.8 4.0 5e-15 54.8 2.7 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.1 EMC88515.1 - 4.2e-08 32.9 0.1 2.2e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF3585 PF12130.3 EMC88516.1 - 3.8e-46 156.4 23.2 5.7e-46 155.9 16.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) LIM PF00412.17 EMC88516.1 - 5.9e-06 26.2 2.7 1.4e-05 25.0 1.9 1.6 1 0 0 1 1 1 1 LIM domain CH PF00307.26 EMC88516.1 - 0.0059 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Homeobox PF00046.24 EMC88517.1 - 5.9e-20 70.6 3.4 7.7e-20 70.2 2.4 1.1 1 0 0 1 1 1 1 Homeobox domain 7tm_1 PF00001.16 EMC88518.1 - 1.5e-46 158.5 16.9 2e-46 158.2 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88518.1 - 2.7e-05 23.4 16.0 3.6e-05 23.0 11.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC88518.1 - 0.015 15.1 3.4 0.015 15.1 2.4 2.8 1 1 0 2 2 2 0 Olfactory receptor Ni_hydr_CYTB PF01292.15 EMC88519.1 - 0.42 9.9 4.6 0.88 8.9 3.2 1.7 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 7tm_1 PF00001.16 EMC88520.1 - 7.4e-17 61.3 18.2 1.1e-16 60.7 12.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Col_cuticle_N PF01484.12 EMC88520.1 - 0.73 9.5 0.0 0.73 9.5 0.0 3.2 4 0 0 4 4 4 0 Nematode cuticle collagen N-terminal domain DUF2373 PF10180.4 EMC88521.1 - 6.4e-24 83.2 1.2 6.4e-24 83.2 0.8 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) YL1 PF05764.8 EMC88521.1 - 0.0032 17.1 7.0 0.0039 16.8 4.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PriCT_2 PF08707.6 EMC88521.1 - 0.037 13.8 0.3 0.056 13.3 0.2 1.3 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) DUF3492 PF11997.3 EMC88521.1 - 0.21 11.0 1.7 0.25 10.8 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) SynMuv_product PF06047.6 EMC88521.1 - 0.34 10.6 5.0 0.55 9.9 3.4 1.4 1 0 0 1 1 1 0 Ras-induced vulval development antagonist GBP_C PF02841.9 EMC88521.1 - 0.62 9.1 7.5 0.79 8.8 5.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain p450 PF00067.17 EMC88522.1 - 6.3e-134 446.9 0.1 7.1e-134 446.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol3_a_NII PF11490.3 EMC88522.1 - 0.063 12.9 0.3 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF4648 PF15505.1 EMC88523.1 - 0.11 12.6 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) ArfGap PF01412.13 EMC88524.1 - 8.7e-27 93.2 0.0 1.5e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EMC88524.1 - 1.3e-15 57.4 0.5 2.7e-08 33.9 0.2 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC88524.1 - 2.7e-14 53.3 0.4 2.9e-09 37.1 0.1 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EMC88524.1 - 9.3e-05 22.4 4.0 0.083 12.9 0.1 2.9 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 EMC88524.1 - 0.0015 18.3 0.2 0.33 10.8 0.0 2.8 3 0 0 3 3 3 1 PH domain Mcp5_PH PF12814.2 EMC88524.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF410 PF04190.8 EMC88525.1 - 5.7e-100 334.1 0.0 6.6e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.12 EMC88525.1 - 0.017 14.9 0.1 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sad1_UNC PF07738.8 EMC88526.1 - 8.5e-43 145.3 0.0 1.6e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1818 PF08848.6 EMC88526.1 - 0.068 13.2 1.8 0.79 9.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) DUF3287 PF11690.3 EMC88526.1 - 0.24 11.4 1.4 3.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF2458 PF10454.4 EMC88526.1 - 0.69 9.7 6.6 0.11 12.4 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) MRP PF09387.5 EMC88527.1 - 2.3e-15 56.8 1.8 3.2e-15 56.3 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP HEAT_2 PF13646.1 EMC88528.1 - 2.2e-15 56.7 0.0 0.0033 17.6 0.0 6.0 3 2 1 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EMC88528.1 - 1.8e-08 34.6 0.2 0.1 12.9 0.0 4.8 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC88528.1 - 1.8e-07 31.4 4.6 0.19 12.2 0.1 6.6 6 1 2 8 8 8 2 HEAT-like repeat HEAT PF02985.17 EMC88528.1 - 1.5e-05 24.6 23.9 0.46 10.7 0.0 9.3 10 0 0 10 10 9 1 HEAT repeat CLASP_N PF12348.3 EMC88528.1 - 0.00015 21.1 9.0 0.0046 16.3 0.2 3.9 3 2 1 4 4 4 2 CLASP N terminal MIF4G PF02854.14 EMC88528.1 - 0.00076 18.9 1.3 0.0026 17.2 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain DUF3535 PF12054.3 EMC88528.1 - 0.0013 17.4 0.1 0.0044 15.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) VHS PF00790.14 EMC88528.1 - 0.0036 16.9 0.3 0.11 12.0 0.0 2.9 3 0 0 3 3 3 1 VHS domain MA3 PF02847.12 EMC88528.1 - 0.025 14.2 0.5 0.16 11.7 0.0 2.6 2 1 0 3 3 3 0 MA3 domain IFRD PF05004.8 EMC88528.1 - 0.026 13.6 0.4 0.026 13.6 0.3 3.2 2 2 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Ipi1_N PF12333.3 EMC88528.1 - 0.085 12.8 4.8 0.51 10.3 0.0 4.5 5 1 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation DUF1068 PF06364.7 EMC88528.1 - 0.16 11.5 5.3 2.9 7.4 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1068) UME PF08064.8 EMC88528.1 - 7.2 6.6 8.1 4.7 7.2 1.3 3.6 2 1 0 3 3 3 0 UME (NUC010) domain cNMP_binding PF00027.24 EMC88529.1 - 6.1e-45 150.9 0.1 3.8e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EMC88529.1 - 1.1e-13 50.3 0.1 2.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit GXGXG PF01493.14 EMC88529.1 - 0.0052 15.8 0.1 0.14 11.1 0.0 2.1 2 0 0 2 2 2 1 GXGXG motif DUF4018 PF13210.1 EMC88531.1 - 3.4 7.0 13.2 0.71 9.2 0.1 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4018) Suppressor_APC PF11414.3 EMC88532.1 - 8.4e-31 105.6 8.0 8.5e-30 102.3 2.5 2.3 2 0 0 2 2 2 2 Adenomatous polyposis coli tumour suppressor protein DUF3134 PF11332.3 EMC88532.1 - 0.1 12.7 0.2 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) CENP-F_leu_zip PF10473.4 EMC88532.1 - 0.11 12.3 9.1 0.58 10.0 1.7 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EMC88532.1 - 0.23 10.6 8.2 1.3 8.1 1.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EMC88532.1 - 0.3 9.7 6.1 1.1 7.8 0.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 EMC88532.1 - 0.31 10.7 7.0 0.12 12.1 0.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EMC88532.1 - 0.54 9.7 6.1 0.073 12.5 1.2 1.8 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 EMC88532.1 - 0.8 9.5 9.3 7.6 6.4 0.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ING PF12998.2 EMC88532.1 - 0.82 9.9 6.5 10 6.4 4.5 2.3 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Glyco_hydro_47 PF01532.15 EMC88533.1 - 7.3e-160 532.5 0.0 2.1e-159 530.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_S28 PF05577.7 EMC88535.1 - 2.2e-77 260.4 0.0 2.6e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EMC88535.1 - 5.9e-07 29.6 0.0 2.3e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC88535.1 - 1.6e-05 24.6 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC88535.1 - 3.6e-05 23.4 1.8 5.9e-05 22.7 1.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMC88535.1 - 0.0047 16.1 0.1 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.6 EMC88535.1 - 0.0079 14.7 0.0 0.014 13.8 0.0 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_2 PF02230.11 EMC88535.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2920 PF11144.3 EMC88535.1 - 0.099 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Kelch_1 PF01344.20 EMC88536.1 - 2.9e-38 129.1 0.0 1.1e-07 31.2 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EMC88536.1 - 8.6e-34 114.3 1.0 9.1e-07 28.8 0.0 5.7 4 2 2 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EMC88536.1 - 2.1e-23 81.7 7.0 0.00025 20.7 0.1 6.5 3 3 3 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 EMC88536.1 - 1.4e-22 79.7 0.0 3e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 EMC88536.1 - 1.2e-17 63.5 7.7 0.00022 21.3 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.10 EMC88536.1 - 6.6e-16 58.0 0.0 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 EMC88536.1 - 4.2e-15 55.3 1.8 0.0015 18.4 0.0 6.8 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 EMC88536.1 - 2.4e-08 33.4 2.7 0.2 11.4 0.0 6.4 6 1 0 6 6 6 2 Kelch motif Pkinase_Tyr PF07714.12 EMC88537.1 - 2.9e-49 167.4 0.0 3.9e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC88537.1 - 1.2e-48 165.5 0.0 2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EMC88537.1 - 0.0048 15.9 0.0 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC88537.1 - 0.011 15.4 0.0 2.2 7.9 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family HSCB_C PF07743.8 EMC88537.1 - 0.44 11.0 2.0 0.85 10.1 0.0 2.3 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Fibrinogen_C PF00147.13 EMC88538.1 - 2e-70 237.0 11.0 2.4e-70 236.8 7.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Collagen PF01391.13 EMC88538.1 - 2.9e-07 29.9 12.3 6.1e-07 28.8 8.5 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF4593 PF15263.1 EMC88538.1 - 6.4 6.6 13.3 1.1 9.1 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4593) MORN PF02493.15 EMC88539.1 - 1.5e-09 37.0 12.6 2.6e-05 23.6 1.2 3.5 3 0 0 3 3 3 3 MORN repeat TLV_coat PF00429.14 EMC88540.1 - 3.2e-06 25.8 0.7 3.9e-06 25.6 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Pkinase PF00069.20 EMC88543.1 - 1.3e-24 86.7 0.0 1.4e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88543.1 - 9.2e-09 34.7 0.0 9.8e-09 34.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC88543.1 - 0.047 12.6 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like ubiquitin PF00240.18 EMC88545.1 - 8.8e-09 34.6 0.0 1.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMC88545.1 - 0.00033 20.2 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMC88545.1 - 0.043 14.0 0.0 0.083 13.1 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain Actin PF00022.14 EMC88546.1 - 1.7e-161 537.0 0.0 1.9e-161 536.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EMC88546.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ARID PF01388.16 EMC88547.1 - 3.7e-27 93.9 0.0 6.7e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF1451 PF07295.6 EMC88547.1 - 0.047 13.4 0.3 0.082 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) NLPC_P60 PF00877.14 EMC88548.1 - 0.0084 15.9 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family LRAT PF04970.8 EMC88548.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SEA PF01390.15 EMC88549.1 - 0.0036 16.9 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 SEA domain TLV_coat PF00429.14 EMC88551.1 - 0.013 13.9 0.3 0.015 13.8 0.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Flavoprotein PF02441.14 EMC88552.1 - 1.6e-45 153.9 0.0 2.1e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein SCAMP PF04144.8 EMC88553.1 - 7e-75 250.7 13.3 8.4e-75 250.5 9.2 1.0 1 0 0 1 1 1 1 SCAMP family ODV-E18 PF10717.4 EMC88553.1 - 0.057 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Alba PF01918.16 EMC88554.1 - 3.9e-16 58.4 1.5 5.1e-16 58.0 1.1 1.2 1 0 0 1 1 1 1 Alba COX5A PF02284.11 EMC88555.1 - 4.9e-57 190.5 0.0 5.5e-57 190.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va FAM219A PF15260.1 EMC88556.1 - 1e-42 145.4 0.4 1.8e-42 144.6 0.3 1.4 1 1 0 1 1 1 1 Protein family FAM219A PMI_typeI PF01238.16 EMC88557.1 - 1.5e-120 402.6 0.0 6.9e-62 209.5 0.0 2.0 2 0 0 2 2 2 2 Phosphomannose isomerase type I Cupin_6 PF12852.2 EMC88557.1 - 0.12 12.0 0.0 5 6.6 0.0 2.3 2 0 0 2 2 2 0 Cupin Pkinase PF00069.20 EMC88558.1 - 1.4e-63 214.4 0.0 2.4e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88558.1 - 1.3e-38 132.6 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.13 EMC88558.1 - 1.7e-36 123.9 12.8 2.2e-22 78.7 0.6 2.7 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Kdo PF06293.9 EMC88558.1 - 2.2e-05 23.6 0.1 6.6e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMC88558.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EMC88558.1 - 0.0046 16.7 1.1 0.0087 15.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family COP23 PF14218.1 EMC88559.1 - 0.026 14.0 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Synaphin PF05835.7 EMC88560.1 - 1.5e-38 132.0 11.2 1.8e-38 131.8 7.8 1.1 1 0 0 1 1 1 1 Synaphin protein PFEMP PF03011.10 EMC88560.1 - 0.064 13.5 4.4 0.052 13.8 2.2 1.4 1 1 0 1 1 1 0 PFEMP DBL domain AHSP PF09236.5 EMC88560.1 - 0.068 13.3 1.4 0.16 12.2 1.0 1.6 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Complex1_LYR PF05347.10 EMC88560.1 - 0.2 11.4 1.9 0.5 10.1 0.8 1.9 1 1 1 2 2 2 0 Complex 1 protein (LYR family) Pkinase_Tyr PF07714.12 EMC88561.1 - 7.2e-49 166.1 0.0 1.4e-28 99.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EMC88561.1 - 5e-21 75.0 0.0 3.4e-10 39.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain p450 PF00067.17 EMC88562.1 - 1.3e-108 363.4 0.1 1.6e-108 363.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMC88563.1 - 1.9e-109 366.2 0.0 2.3e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YjeF_N PF03853.10 EMC88564.1 - 7.5e-18 64.6 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EMC88564.1 - 5.3e-13 49.3 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.2 EMC88564.1 - 1.9e-12 46.7 0.0 6.9e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Scd6-like Sm domain Pkinase PF00069.20 EMC88565.1 - 1.9e-54 184.5 0.1 2.7e-54 184.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88565.1 - 7.4e-23 80.9 0.2 2.7e-21 75.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CEP170_C PF15308.1 EMC88565.1 - 2.6 6.1 11.8 3.7 5.6 8.2 1.1 1 0 0 1 1 1 0 CEP170 C-terminus Pkinase PF00069.20 EMC88566.1 - 3.9e-72 242.5 0.0 5e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88566.1 - 2.1e-36 125.3 0.0 2.8e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMC88566.1 - 1.4e-05 24.5 0.2 2.3e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMC88566.1 - 0.00018 20.6 0.1 0.0004 19.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_trans_3N PF02885.12 EMC88566.1 - 0.043 13.4 0.3 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Choline_kinase PF01633.15 EMC88566.1 - 0.066 12.7 0.3 0.16 11.5 0.2 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_7 PF13499.1 EMC88567.1 - 4.6e-14 52.3 1.9 8.2e-11 41.8 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC88567.1 - 1.1e-09 36.8 9.0 0.00013 20.9 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EMC88567.1 - 1.1e-06 28.0 6.8 0.029 14.2 0.3 3.8 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EMC88567.1 - 1.7e-05 24.2 8.4 0.014 15.0 2.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC88567.1 - 7.2e-05 21.9 10.0 0.011 15.1 0.5 3.9 4 0 0 4 4 4 2 EF hand PMBR PF09373.5 EMC88567.1 - 0.017 15.0 0.0 6.4 6.9 0.0 3.4 4 0 0 4 4 4 0 Pseudomurein-binding repeat Peptidase_C2 PF00648.16 EMC88567.1 - 0.14 11.0 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Calpain family cysteine protease EF-hand_4 PF12763.2 EMC88567.1 - 0.18 11.5 0.9 1.7 8.4 0.1 2.2 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Iso_dh PF00180.15 EMC88568.1 - 1.9e-110 369.1 0.0 2.2e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AMP-binding PF00501.23 EMC88569.1 - 1.2e-90 303.9 0.0 1.5e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DnaJ PF00226.26 EMC88570.1 - 1.4e-27 95.2 1.9 2.3e-27 94.5 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMC88570.1 - 1.7e-22 79.1 0.8 1e-17 63.7 0.0 2.7 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMC88570.1 - 1.1e-13 51.0 18.9 2e-13 50.1 13.1 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EMC88570.1 - 0.19 11.4 10.4 1.5 8.5 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 EMC88570.1 - 6.7 6.5 6.3 4.6 7.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) WD40 PF00400.27 EMC88571.1 - 1e-58 193.1 20.5 1.3e-11 43.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMC88571.1 - 1.3e-09 38.0 0.0 6.3e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMC88571.1 - 2e-06 26.3 1.9 0.21 9.8 0.0 3.6 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nup160 PF11715.3 EMC88571.1 - 5.1e-05 21.6 2.0 0.054 11.6 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 GSDH PF07995.6 EMC88571.1 - 0.00089 18.4 0.0 0.24 10.4 0.0 2.6 1 1 0 2 2 2 2 Glucose / Sorbosone dehydrogenase PD40 PF07676.7 EMC88571.1 - 0.0019 17.7 0.2 2.4 7.9 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ PF01011.16 EMC88571.1 - 0.016 14.7 2.4 13 5.5 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat DUF2415 PF10313.4 EMC88571.1 - 0.021 14.4 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Nucleoporin_N PF08801.6 EMC88571.1 - 0.027 13.2 2.1 0.51 9.0 0.0 3.0 1 1 1 2 2 2 0 Nup133 N terminal like DUF3312 PF11768.3 EMC88571.1 - 0.081 11.1 0.0 0.17 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Lipocalin PF00061.18 EMC88572.1 - 4.4e-17 62.4 0.3 4.7e-17 62.3 0.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Aconitase PF00330.15 EMC88573.1 - 7.9e-114 380.6 0.0 1e-103 347.3 0.0 2.1 2 0 0 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMC88573.1 - 1.3e-38 132.1 0.0 2.1e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain APH PF01636.18 EMC88574.1 - 9e-21 74.7 0.0 1.2e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMC88574.1 - 0.044 12.9 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 EMC88574.1 - 0.099 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome PF00227.21 EMC88575.1 - 4e-56 189.3 0.0 5.2e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC88575.1 - 1.1e-14 53.3 0.2 1.9e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phenol_monoox PF04663.7 EMC88575.1 - 0.065 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Neur_chan_LBD PF02931.18 EMC88576.1 - 4.5e-71 238.4 0.8 5.8e-71 238.0 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC88576.1 - 6.7e-59 199.6 12.3 4.3e-46 157.7 6.3 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 EMC88577.1 - 2.3e-85 286.2 5.6 2.9e-85 285.9 3.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC88577.1 - 1.6e-72 243.1 1.9 2.6e-72 242.4 1.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC88578.1 - 1.9e-82 276.7 2.6 2.5e-82 276.3 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 EMC88578.1 - 3.9e-70 235.3 2.3 6.3e-70 234.6 1.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.4 EMC88578.1 - 0.0027 17.1 0.5 0.0027 17.1 0.4 2.2 3 0 0 3 3 3 1 Region of unknown function (DUF2417) UQ_con PF00179.21 EMC88579.1 - 4.1e-11 42.4 0.0 5.5e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC88579.1 - 0.0017 18.0 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMC88579.1 - 0.095 12.6 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 RWD domain RNA_pol_Rpb2_4 PF04566.8 EMC88579.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 KIAA1430 PF13879.1 EMC88579.1 - 0.43 11.0 5.9 2.5 8.5 0.2 2.7 3 0 0 3 3 3 0 KIAA1430 homologue FIST_C PF10442.4 EMC88580.1 - 1.9e-10 40.8 0.0 3.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 FIST C domain FIST PF08495.5 EMC88580.1 - 0.00036 19.7 0.0 0.73 8.9 0.0 3.0 2 1 1 3 3 3 3 FIST N domain PBP_GOBP PF01395.17 EMC88580.1 - 0.052 13.1 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 PBP/GOBP family Toprim_3 PF13362.1 EMC88580.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Toprim domain DUF2759 PF10958.3 EMC88580.1 - 0.11 12.1 1.2 0.44 10.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) EGF PF00008.22 EMC88582.1 - 0.035 14.0 2.1 0.035 14.0 1.5 2.0 2 1 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 EMC88582.1 - 0.066 13.1 0.7 0.066 13.1 0.5 1.8 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EMC88582.1 - 0.15 12.2 8.1 0.069 13.3 2.7 2.5 2 1 0 2 2 2 0 EGF-like domain IncA PF04156.9 EMC88582.1 - 0.16 11.5 0.5 0.2 11.2 0.3 1.2 1 0 0 1 1 1 0 IncA protein Ion_trans PF00520.26 EMC88583.1 - 7.6e-05 22.0 3.0 7.6e-05 22.0 2.1 1.5 2 0 0 2 2 2 1 Ion transport protein Fib_alpha PF08702.5 EMC88583.1 - 0.11 12.5 1.7 0.44 10.6 1.2 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_S10 PF00450.17 EMC88583.1 - 0.64 9.1 2.0 0.55 9.3 0.4 1.5 2 0 0 2 2 2 0 Serine carboxypeptidase MoaF PF10703.4 EMC88584.1 - 0.73 8.8 4.9 0.98 8.4 3.4 1.2 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F ETF_alpha PF00766.14 EMC88585.1 - 2.3e-39 132.8 1.2 6.4e-39 131.4 0.1 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EMC88585.1 - 9.1e-38 129.5 0.1 1.4e-37 128.9 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GRP PF07172.6 EMC88587.1 - 0.11 12.9 4.8 0.11 12.9 3.3 1.1 1 0 0 1 1 1 0 Glycine rich protein family HATPase_c PF02518.21 EMC88588.1 - 3.1e-19 68.7 0.0 2.5e-18 65.8 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carb_anhydrase PF00194.16 EMC88589.1 - 1.7e-63 213.9 0.0 1.9e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase V-set PF07686.12 EMC88590.1 - 8.7e-14 51.3 0.0 9.5e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC88590.1 - 8e-05 22.6 0.3 0.00099 19.1 0.2 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC88590.1 - 0.00017 21.3 0.1 0.00081 19.1 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC88590.1 - 0.01 15.9 0.1 0.013 15.6 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.1 EMC88590.1 - 0.044 14.2 1.2 0.34 11.4 0.8 2.1 1 1 0 1 1 1 0 Immunoglobulin domain DNA_ligase_ZBD PF03119.11 EMC88590.1 - 0.15 11.8 0.2 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain RHIM PF12721.2 EMC88590.1 - 0.67 10.4 4.0 0.18 12.2 0.7 1.9 2 1 0 2 2 2 0 RIP homotypic interaction motif V-set PF07686.12 EMC88591.1 - 1.3e-15 57.2 0.0 1.6e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC88591.1 - 0.00016 21.6 1.1 0.0053 16.8 0.7 2.2 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC88591.1 - 0.00079 19.2 0.0 0.0031 17.3 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC88591.1 - 0.0015 18.5 0.1 0.0021 18.1 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC88591.1 - 0.0034 17.8 2.6 0.077 13.5 1.8 2.2 1 1 0 1 1 1 1 Immunoglobulin domain RHIM PF12721.2 EMC88591.1 - 5.5 7.4 6.6 2.3 8.6 1.9 2.3 2 1 0 2 2 2 0 RIP homotypic interaction motif V-set PF07686.12 EMC88592.1 - 3.9e-17 62.1 0.4 4.4e-17 62.0 0.3 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC88592.1 - 9.9e-05 22.3 1.1 0.0019 18.2 0.8 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC88592.1 - 0.00026 20.7 0.1 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC88592.1 - 0.0012 19.3 4.0 0.017 15.6 2.7 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC88592.1 - 0.0028 17.7 0.2 0.0039 17.2 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Toxin_58 PF15536.1 EMC88592.1 - 0.03 14.1 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 58 V-set PF07686.12 EMC88593.1 - 1.5e-15 57.0 0.8 1.7e-15 56.8 0.6 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC88593.1 - 0.00025 20.8 0.1 0.00073 19.3 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC88593.1 - 0.00086 19.7 5.2 0.011 16.1 3.6 2.3 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC88593.1 - 0.00097 19.2 0.9 0.0017 18.4 0.6 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC88593.1 - 0.0073 16.4 0.4 0.0098 16.0 0.3 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC88594.1 - 1.1e-13 51.0 0.1 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC88594.1 - 0.00012 22.0 0.9 0.00031 20.8 0.6 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC88594.1 - 0.0053 16.5 0.0 0.016 15.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC88594.1 - 0.0071 16.8 4.1 0.16 12.4 2.8 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC88594.1 - 0.021 14.9 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC88595.1 - 3.8e-16 58.9 0.3 4.1e-16 58.9 0.2 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC88595.1 - 0.00016 21.7 1.7 0.0008 19.4 1.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC88595.1 - 0.00017 21.6 0.3 0.00023 21.2 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC88595.1 - 0.00029 20.6 0.1 0.00074 19.3 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC88595.1 - 0.00038 20.9 4.8 0.0017 18.8 3.3 1.9 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC88596.1 - 5.4e-09 35.9 0.2 5.9e-09 35.8 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC88596.1 - 0.13 12.7 3.3 0.41 11.1 2.3 1.8 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 EMC88597.1 - 2.9e-17 62.5 0.2 3.1e-17 62.4 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC88597.1 - 3.7e-05 23.5 0.1 8.4e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC88597.1 - 0.0003 21.2 3.3 0.0015 18.9 2.3 2.0 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC88597.1 - 0.00047 20.2 1.6 0.0037 17.3 1.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC88597.1 - 0.0019 18.3 0.1 0.0026 17.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC88598.1 - 2.9e-15 56.1 0.0 3.6e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC88598.1 - 2.1e-06 27.7 0.4 1.2e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 EMC88598.1 - 5.2e-05 23.0 0.0 9.8e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC88598.1 - 0.0014 18.7 0.2 0.0028 17.7 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC88598.1 - 0.14 12.6 1.5 0.47 11.0 1.0 1.8 1 1 0 1 1 1 0 Immunoglobulin domain CHCH PF06747.8 EMC88599.1 - 8.6e-08 31.9 5.8 8.6e-08 31.9 4.0 1.6 2 0 0 2 2 2 1 CHCH domain Peptidase_M10 PF00413.19 EMC88600.1 - 5e-55 185.4 0.0 8.3e-55 184.7 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC88600.1 - 4.4e-44 147.9 13.8 2.5e-12 46.2 0.7 4.5 4 0 0 4 4 4 4 Hemopexin Peptidase_M43 PF05572.8 EMC88600.1 - 0.0015 18.1 0.1 0.0027 17.3 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EMC88600.1 - 0.0034 17.8 0.1 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EMC88600.1 - 0.0045 16.4 0.2 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 EMC88600.1 - 0.0068 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMC88600.1 - 0.01 15.3 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC88600.1 - 0.057 13.4 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 EMC88600.1 - 0.13 11.7 0.1 9.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) SNF5 PF04855.7 EMC88601.1 - 6e-65 219.1 4.5 3.5e-63 213.3 1.4 2.7 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 DUF1679 PF07914.6 EMC88601.1 - 0.0041 15.8 0.0 0.0061 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DER1 PF04511.10 EMC88602.1 - 1.3e-60 204.2 13.9 1.5e-60 204.1 9.6 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 EMC88602.1 - 0.085 12.8 16.4 0.13 12.2 11.4 1.3 1 0 0 1 1 1 0 Rhomboid family Sugar_tr PF00083.19 EMC88603.1 - 9e-91 304.7 23.5 1e-90 304.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC88603.1 - 3.1e-24 85.3 45.9 2.1e-22 79.3 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC88604.1 - 2.1e-28 99.1 8.3 2.4e-28 98.9 5.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC88604.1 - 8.3e-16 57.6 6.6 9.2e-16 57.4 4.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMC88604.1 - 1.2e-05 23.9 0.9 1.4e-05 23.7 0.6 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 EMC88605.1 - 5e-94 315.4 23.7 5.6e-94 315.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC88605.1 - 5.6e-29 100.9 27.9 4.9e-20 71.5 0.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EMC88605.1 - 0.0017 16.5 1.7 0.79 7.7 0.3 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector PUCC PF03209.10 EMC88605.1 - 0.5 9.0 15.8 0.055 12.1 2.3 2.2 2 0 0 2 2 2 0 PUCC protein DEAD PF00270.24 EMC88606.1 - 1e-42 145.5 0.1 2.8e-42 144.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC88606.1 - 8.4e-24 83.2 0.5 1.9e-23 82.0 0.2 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC88606.1 - 3.5e-14 53.0 0.0 5.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 EMC88606.1 - 0.0025 16.4 0.0 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 EMC88606.1 - 0.0031 16.3 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EMC88606.1 - 0.0076 15.5 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 EMC88606.1 - 0.019 15.1 0.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF1253 PF06862.7 EMC88606.1 - 0.028 12.8 0.2 0.091 11.1 0.0 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1253) IMS_HHH PF11798.3 EMC88606.1 - 0.085 12.9 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 IMS family HHH motif AAA_19 PF13245.1 EMC88606.1 - 0.11 12.2 0.4 0.47 10.2 0.1 2.2 2 1 0 2 2 2 0 Part of AAA domain GST_C PF00043.20 EMC88607.1 - 1e-10 41.4 0.0 1.6e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC88607.1 - 1.7e-06 27.7 0.0 3.6e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC88607.1 - 4.8e-05 23.7 0.0 7.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC88607.1 - 0.00014 21.9 0.0 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMC88607.1 - 0.008 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC88608.1 - 4.2e-09 36.2 0.0 7.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC88608.1 - 4.8e-06 26.3 0.2 2.2e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC88608.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC88608.1 - 0.0004 20.8 0.0 0.00061 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC88608.1 - 0.00087 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SH3_2 PF07653.12 EMC88609.1 - 1.4e-24 85.3 0.2 2.3e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMC88609.1 - 6.4e-22 76.6 0.2 1.2e-16 59.8 0.1 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC88609.1 - 1.5e-18 66.0 1.5 2.9e-11 42.7 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.19 EMC88610.1 - 3.1e-22 78.1 0.0 3.8e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Kelch_1 PF01344.20 EMC88611.1 - 3.2e-50 167.4 10.0 1.6e-13 49.9 0.0 6.0 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EMC88611.1 - 5.4e-42 140.2 0.7 8.9e-09 35.1 0.0 5.7 3 1 2 5 5 5 5 Kelch motif BTB PF00651.26 EMC88611.1 - 4.5e-27 94.2 1.6 5.4e-25 87.5 0.2 2.4 1 1 1 2 2 2 2 BTB/POZ domain Kelch_2 PF07646.10 EMC88611.1 - 3.6e-24 83.5 5.3 1.1e-05 24.9 0.0 6.0 5 2 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EMC88611.1 - 4.3e-23 80.8 1.0 2.7e-06 27.3 0.0 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC88611.1 - 7.7e-21 73.5 0.3 0.006 16.3 0.1 5.5 4 1 1 5 5 5 5 Galactose oxidase, central domain BACK PF07707.10 EMC88611.1 - 4.1e-15 55.4 0.2 1.4e-14 53.7 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 EMC88611.1 - 6.4e-09 35.5 1.9 0.19 11.7 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Med15 PF09606.5 EMC88612.1 - 5.6e-270 898.0 183.0 6.3e-270 897.8 126.8 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Caldesmon PF02029.10 EMC88612.1 - 0.0017 16.8 19.4 0.0025 16.2 13.4 1.1 1 0 0 1 1 1 1 Caldesmon mit_SMPDase PF14724.1 EMC88613.1 - 0 1535.4 3.4 0 1535.2 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase G_glu_transpept PF01019.16 EMC88614.1 - 1.6e-130 435.9 0.0 1.9e-130 435.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.16 EMC88615.1 - 5.6e-170 566.1 0.0 6.3e-170 566.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase LRR_4 PF12799.2 EMC88616.1 - 5.8e-05 22.6 0.5 0.00042 19.8 0.2 2.3 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC88616.1 - 0.0044 16.9 1.4 0.97 9.7 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 EMC88616.1 - 0.019 14.9 3.2 1.2 9.3 0.3 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 EMC88616.1 - 0.04 13.6 1.5 0.14 11.8 0.7 2.1 1 1 0 1 1 1 0 Leucine rich repeat LRR_7 PF13504.1 EMC88616.1 - 0.11 12.7 1.0 1.1 9.7 0.1 3.1 2 0 0 2 2 2 0 Leucine rich repeat LSM PF01423.17 EMC88617.1 - 2.2e-13 49.5 0.2 3e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.13 EMC88617.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Kringle domain Guanylate_cyc_2 PF09778.4 EMC88618.1 - 4.1e-94 313.6 7.8 4.7e-94 313.5 5.4 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.1 EMC88618.1 - 2.5e-11 44.1 0.0 7.3e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase_C39 like family DUF3335 PF11814.3 EMC88618.1 - 0.00021 20.5 0.2 0.21 10.7 0.1 2.3 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.10 EMC88618.1 - 0.00034 20.4 0.1 0.0036 17.1 0.1 2.3 2 1 0 2 2 2 1 Peptidase C39 family Peptidase_C70 PF12385.3 EMC88618.1 - 0.019 14.6 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 DEDD_Tnp_IS110 PF01548.12 EMC88618.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Transposase TMEM52 PF14979.1 EMC88618.1 - 0.025 14.5 3.3 0.045 13.6 2.3 1.4 1 0 0 1 1 1 0 Transmembrane 52 Doppel PF11466.3 EMC88618.1 - 0.047 13.2 0.3 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel CN_hydrolase PF00795.17 EMC88619.1 - 7.1e-39 133.0 0.1 9.3e-39 132.7 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.16 EMC88620.1 - 9.4e-53 178.9 16.8 1.1e-52 178.7 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88620.1 - 6.7e-08 31.9 20.0 9.9e-07 28.1 13.9 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC88620.1 - 0.058 12.4 26.7 0.45 9.5 18.5 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Ni_hydr_CYTB PF01292.15 EMC88620.1 - 2.4 7.5 9.4 0.037 13.4 0.5 2.2 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 PgaD PF13994.1 EMC88620.1 - 3.1 7.2 6.6 11 5.4 0.3 2.9 3 0 0 3 3 3 0 PgaD-like protein WEMBL PF05701.6 EMC88621.1 - 0.00012 20.7 49.8 0.00012 20.7 34.5 3.2 2 1 1 3 3 3 2 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 EMC88621.1 - 0.0016 18.1 11.4 0.0016 18.1 7.9 6.7 3 2 2 5 5 5 3 TPR/MLP1/MLP2-like protein RhoGAP PF00620.22 EMC88622.1 - 5.1e-50 169.0 0.2 8.8e-49 165.0 0.0 2.6 2 0 0 2 2 2 1 RhoGAP domain Bcr-Abl_Oligo PF09036.5 EMC88622.1 - 1.2e-45 153.3 0.7 4.8e-45 151.4 0.5 2.1 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain RhoGEF PF00621.15 EMC88622.1 - 2.1e-36 125.5 0.9 4.4e-36 124.4 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.25 EMC88622.1 - 4.4e-10 39.2 0.0 1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.24 EMC88622.1 - 2.2e-08 34.2 0.3 9.2e-08 32.2 0.2 2.1 1 0 0 1 1 1 1 PH domain FUN14 PF04930.10 EMC88622.1 - 0.24 11.6 0.2 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 FUN14 family Ras PF00071.17 EMC88623.1 - 9.1e-45 151.9 0.2 1.3e-44 151.4 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88623.1 - 1.2e-16 61.2 0.0 2.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC88623.1 - 9.9e-15 54.2 0.0 1.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC88623.1 - 8.1e-06 25.1 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC88623.1 - 9.1e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC88623.1 - 0.00064 19.2 0.0 0.013 14.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EMC88623.1 - 0.021 14.5 0.1 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EMC88623.1 - 0.023 13.9 0.0 0.34 10.1 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 EMC88623.1 - 0.11 12.4 0.1 0.24 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain HEAT_2 PF13646.1 EMC88624.1 - 2.3e-19 69.4 11.1 3.1e-08 33.7 0.2 4.2 2 1 2 4 4 4 4 HEAT repeats HEAT PF02985.17 EMC88624.1 - 1.4e-15 55.8 4.6 0.049 13.7 0.0 7.2 7 0 0 7 7 7 4 HEAT repeat Arm PF00514.18 EMC88624.1 - 1.2e-14 53.5 6.4 0.0014 18.3 0.0 7.5 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EMC88624.1 - 3.9e-12 45.2 0.4 3.5e-09 35.5 0.3 2.8 1 1 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 EMC88624.1 - 1e-09 37.2 1.5 0.00031 19.1 0.1 3.0 2 1 0 3 3 3 3 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 EMC88624.1 - 1.7e-08 34.6 7.7 0.0024 18.2 0.1 6.3 5 1 1 6 6 6 1 HEAT-like repeat Arm_2 PF04826.8 EMC88624.1 - 4.7e-07 29.1 0.0 0.0064 15.6 0.0 2.4 1 1 1 2 2 2 2 Armadillo-like CLASP_N PF12348.3 EMC88624.1 - 3.7e-05 23.1 0.1 0.67 9.2 0.0 3.6 1 1 2 4 4 4 2 CLASP N terminal Cnd1 PF12717.2 EMC88624.1 - 0.00018 21.3 0.3 3.8 7.3 0.0 3.9 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IU_nuc_hydro PF01156.14 EMC88624.1 - 0.0012 18.1 0.1 0.0025 17.0 0.0 1.5 2 0 0 2 2 2 1 Inosine-uridine preferring nucleoside hydrolase DUF2435 PF10363.4 EMC88624.1 - 0.011 15.6 0.1 8.6 6.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) RICTOR_N PF14664.1 EMC88624.1 - 0.016 13.8 0.4 1.7 7.1 0.0 3.0 2 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term ALF PF03752.8 EMC88624.1 - 0.017 15.0 0.1 3.6 7.5 0.0 3.0 3 0 0 3 3 3 0 Short repeats of unknown function G-alpha PF00503.15 EMC88625.1 - 4.2e-129 430.6 1.3 5.2e-129 430.3 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC88625.1 - 8.9e-17 60.8 0.3 6.4e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC88625.1 - 0.0006 19.0 5.7 0.023 13.8 0.3 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMC88625.1 - 0.0017 18.3 0.1 0.31 10.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EMC88625.1 - 0.0098 15.4 0.1 0.03 13.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2951 PF11166.3 EMC88625.1 - 0.0099 15.7 1.5 0.32 10.8 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2951) TniB PF05621.6 EMC88625.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Miro PF08477.8 EMC88625.1 - 0.12 12.8 2.2 6.6 7.2 0.2 2.8 3 0 0 3 3 3 0 Miro-like protein SSF PF00474.12 EMC88626.1 - 2.4e-166 553.3 24.6 3.7e-166 552.7 17.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family 14-3-3 PF00244.15 EMC88627.1 - 1.3e-109 364.8 12.4 1.4e-109 364.6 8.6 1.0 1 0 0 1 1 1 1 14-3-3 protein CodY PF06018.9 EMC88627.1 - 0.044 13.0 0.2 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 CodY GAF-like domain DUF837 PF05769.6 EMC88627.1 - 0.13 11.8 4.2 2.1 7.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Homeobox PF00046.24 EMC88628.1 - 2.4e-10 39.8 2.1 6.9e-10 38.4 1.5 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC88628.1 - 2e-07 30.5 1.4 2.9e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_1 PF01527.15 EMC88628.1 - 0.037 13.9 1.1 0.085 12.8 0.2 2.0 2 1 0 2 2 2 0 Transposase CENP-B_N PF04218.8 EMC88628.1 - 0.12 11.8 0.4 0.42 10.0 0.0 2.1 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain DUF3608 PF12257.3 EMC88629.1 - 1.8e-59 200.9 0.2 2.7e-59 200.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EMC88629.1 - 5.5e-11 42.0 0.0 1.7e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Las1 PF04031.8 EMC88629.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Las1-like DUF3375 PF11855.3 EMC88629.1 - 0.013 14.2 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) PS_Dcarbxylase PF02666.10 EMC88630.1 - 2.4e-72 242.4 0.0 3.4e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Tantalus PF15386.1 EMC88630.1 - 1.1e-14 53.9 1.2 3.1e-14 52.4 0.8 1.8 1 0 0 1 1 1 1 Drosophila Tantalus-like TGS PF02824.16 EMC88631.1 - 3.8e-24 84.3 0.1 9e-24 83.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMC88631.1 - 2.1e-17 63.1 0.1 5.3e-17 61.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC88631.1 - 7.1e-11 41.6 0.0 9.1e-10 38.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMC88631.1 - 0.00075 18.9 0.1 0.57 9.5 0.0 3.6 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMC88631.1 - 0.0013 18.6 0.4 1.7 8.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EMC88631.1 - 0.0038 16.0 0.2 0.023 13.5 0.0 2.0 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EMC88631.1 - 0.021 15.3 0.0 0.066 13.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EMC88631.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 EMC88632.1 - 9.4e-31 103.8 41.4 2.2e-05 24.4 0.0 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC88632.1 - 6.3e-24 82.8 50.7 3.9e-05 23.7 0.6 8.1 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC88632.1 - 1.6e-16 59.6 56.0 6.1e-07 29.4 1.5 9.3 10 0 0 10 10 9 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC88632.1 - 7.9e-10 38.5 28.2 0.11 12.7 0.0 8.2 7 1 1 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC88632.1 - 3.6e-08 33.3 28.6 0.3 11.3 0.0 8.0 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC88632.1 - 0.00065 19.7 29.8 0.14 12.2 1.0 5.6 4 1 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMC88632.1 - 0.0048 16.7 4.6 0.017 15.0 0.9 7.4 8 0 0 8 8 8 2 C2H2-type zinc finger ROS_MUCR PF05443.6 EMC88632.1 - 0.012 15.4 0.2 3.4 7.4 0.0 2.7 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein XPA_N PF01286.13 EMC88632.1 - 0.015 14.9 16.1 0.09 12.4 0.0 6.1 7 0 0 7 7 7 0 XPA protein N-terminal ARS2 PF04959.8 EMC88632.1 - 0.26 11.4 4.6 1.3 9.1 0.1 3.2 2 1 1 3 3 3 0 Arsenite-resistance protein 2 DUF629 PF04780.7 EMC88632.1 - 0.46 8.9 5.1 1.3 7.4 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF629) Zn_ribbon_2 PF12674.2 EMC88632.1 - 1.8 8.9 16.0 0.81 10.0 1.3 3.8 3 2 1 5 5 5 0 Putative zinc ribbon domain zf-C2H2_2 PF12756.2 EMC88632.1 - 1.8 8.6 28.2 20 5.3 1.6 7.0 3 1 4 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 EMC88632.1 - 2 8.5 15.5 1.4 9.0 0.1 5.2 6 0 0 6 6 6 0 zinc-finger GAGA PF09237.6 EMC88632.1 - 3.3 7.3 22.3 3.7 7.2 0.3 5.8 6 1 1 7 7 7 0 GAGA factor AT_hook PF02178.14 EMC88632.1 - 6.8 6.7 13.5 0.061 13.0 2.8 2.4 2 0 0 2 2 2 0 AT hook motif zf-FPG_IleRS PF06827.9 EMC88632.1 - 8.5 6.1 17.8 31 4.3 0.0 6.5 6 1 0 6 6 6 0 Zinc finger found in FPG and IleRS Ribosomal_L37ae PF01780.14 EMC88632.1 - 8.5 6.3 10.5 11 5.9 0.1 4.7 4 1 0 4 4 4 0 Ribosomal L37ae protein family TMEM154 PF15102.1 EMC88633.1 - 0.031 13.9 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family EI24 PF07264.6 EMC88633.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) zf-C3HC4_2 PF13923.1 EMC88634.1 - 1.5e-10 40.9 9.0 2e-10 40.5 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC88634.1 - 1.5e-10 40.5 7.5 2.1e-10 40.0 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC88634.1 - 2.6e-10 39.7 5.1 3.7e-10 39.2 3.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC88634.1 - 1.4e-09 37.6 9.4 1.9e-09 37.1 6.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC88634.1 - 1.1e-07 31.4 6.5 1.6e-07 30.9 4.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC88634.1 - 5.5e-06 25.9 4.8 4.4e-05 23.0 1.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMC88634.1 - 6.9e-05 22.6 2.6 0.0001 22.0 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC88634.1 - 0.00011 22.0 7.7 0.00016 21.4 5.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EMC88634.1 - 0.00051 19.7 2.8 0.00078 19.1 1.9 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 EMC88634.1 - 0.0021 18.0 9.4 0.004 17.2 6.5 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 EMC88634.1 - 0.0062 15.7 0.1 0.0079 15.4 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 EMC88634.1 - 0.018 14.5 5.4 0.038 13.5 3.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EMC88634.1 - 0.047 13.4 1.5 0.1 12.3 0.9 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 EMC88634.1 - 0.054 13.0 4.6 0.25 10.9 3.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 EMC88634.1 - 0.66 9.9 3.5 0.96 9.3 2.4 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 EMC88634.1 - 1.8 8.5 8.8 31 4.5 6.3 2.4 1 1 1 2 2 2 0 IBR domain DUF1272 PF06906.6 EMC88634.1 - 2.5 7.9 5.8 14 5.6 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) RabGAP-TBC PF00566.13 EMC88635.1 - 0.038 13.4 1.5 0.049 13.0 1.0 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain HNF-1B_C PF04812.8 EMC88636.1 - 4.1e-107 357.0 35.9 4.1e-107 357.0 24.9 2.2 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.8 EMC88636.1 - 1.4e-85 285.9 2.5 4e-85 284.4 1.7 1.8 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C PF04813.7 EMC88636.1 - 5e-35 119.6 16.2 5e-35 119.6 11.2 3.1 2 1 1 3 3 3 1 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Homeobox PF00046.24 EMC88636.1 - 1.7e-06 27.5 0.2 8.2e-06 25.3 0.1 2.2 1 1 0 1 1 1 1 Homeobox domain Peptidase_A22B PF04258.8 EMC88637.1 - 1.5e-96 323.3 10.7 1.9e-96 323.0 7.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Acyl-CoA_dh_1 PF00441.19 EMC88638.1 - 1.5e-51 174.4 8.5 2.2e-51 173.8 5.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMC88638.1 - 7.3e-36 123.1 0.2 3.7e-35 120.9 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMC88638.1 - 3.7e-23 82.2 5.0 6.1e-23 81.5 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMC88638.1 - 4e-18 64.6 1.9 7.3e-18 63.8 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain GMP_PDE_delta PF05351.6 EMC88639.1 - 8.8e-79 262.7 1.6 1e-78 262.5 1.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Malectin PF11721.3 EMC88640.1 - 2.5e-36 125.0 0.2 2.5e-36 125.0 0.1 1.5 2 0 0 2 2 2 1 Di-glucose binding within endoplasmic reticulum EF-hand_1 PF00036.27 EMC88641.1 - 4.9e-30 100.5 14.6 2.6e-10 38.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EMC88641.1 - 6.1e-24 81.7 5.4 6.2e-09 35.0 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EMC88641.1 - 7.6e-24 83.6 6.8 7.8e-16 57.9 0.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC88641.1 - 1.1e-20 71.9 12.3 2.1e-08 33.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EMC88641.1 - 6.8e-20 70.4 13.7 2.1e-13 49.6 0.4 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EMC88641.1 - 5.6e-09 35.7 0.1 0.0036 17.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EMC88641.1 - 0.00014 21.8 0.0 0.0024 17.9 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region POTRA_2 PF08479.6 EMC88641.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 POTRA domain, ShlB-type EF-hand_4 PF12763.2 EMC88641.1 - 0.0091 15.7 2.1 0.051 13.3 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.13 EMC88641.1 - 0.2 11.4 9.8 1.9 8.3 0.9 3.5 3 0 0 3 3 3 0 Dockerin type I repeat zf-C3HC4_2 PF13923.1 EMC88642.1 - 4e-09 36.3 10.1 1.3e-08 34.7 7.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC88642.1 - 5.1e-08 32.6 9.1 1.2e-07 31.4 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC88642.1 - 3.7e-07 29.7 6.7 1.1e-06 28.2 4.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMC88642.1 - 4.2e-07 29.5 8.4 1.3e-06 27.9 5.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC88642.1 - 4.4e-06 26.2 5.5 1.2e-05 24.8 3.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC88642.1 - 0.0027 17.7 7.9 0.006 16.6 5.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC88642.1 - 0.0041 16.9 9.1 0.0041 16.9 6.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC88642.1 - 0.005 16.5 5.9 0.019 14.6 4.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EMC88642.1 - 0.024 14.4 5.6 0.08 12.7 3.9 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EMC88642.1 - 0.026 14.3 5.6 0.051 13.4 3.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EMC88642.1 - 2.1 7.9 11.3 6.9 6.2 7.8 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMC88642.1 - 3 7.4 6.6 9.2 5.8 4.6 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ubie_methyltran PF01209.13 EMC88643.1 - 8.4e-90 299.9 0.0 1.1e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EMC88643.1 - 8.1e-18 64.7 0.0 1.6e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC88643.1 - 2e-16 59.9 0.0 6.5e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC88643.1 - 3.3e-11 43.4 0.0 6.5e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC88643.1 - 2e-08 34.5 0.0 9.8e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC88643.1 - 2.5e-08 34.4 0.0 2.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC88643.1 - 7.4e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC88643.1 - 9.1e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMC88643.1 - 0.0069 16.0 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase UPF0020 PF01170.13 EMC88643.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 EMC88643.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Dynein_light PF01221.13 EMC88644.1 - 1.5e-46 156.2 1.5 1.6e-46 156.1 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.24 EMC88644.1 - 0.0038 16.3 0.1 0.0044 16.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ground-like PF04155.13 EMC88644.1 - 0.036 14.3 0.2 0.051 13.8 0.1 1.4 1 1 0 1 1 1 0 Ground-like domain CotJB PF12652.2 EMC88644.1 - 0.086 12.9 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 CotJB protein Imm28 PF15574.1 EMC88644.1 - 0.11 12.1 0.3 0.16 11.5 0.2 1.4 1 1 0 1 1 1 0 Immunity protein 28 SpoIIIAH PF12685.2 EMC88644.1 - 0.46 9.9 2.9 0.54 9.7 2.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Glu-tRNAGln PF02686.10 EMC88645.1 - 1.6e-15 56.6 0.1 2.3e-15 56.1 0.1 1.3 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit COX6A PF02046.10 EMC88646.1 - 7.3e-29 100.0 0.1 8e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RRM_1 PF00076.17 EMC88647.1 - 1.2e-11 44.0 0.6 2e-11 43.3 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC88647.1 - 3.4e-10 39.7 0.1 5e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phospholip_A2_1 PF00068.14 EMC88648.1 - 6.6e-41 139.1 15.0 7.5e-41 139.0 10.4 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 EMC88648.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.7 EMC88648.1 - 1 9.3 13.0 17 5.4 9.0 2.2 1 1 0 1 1 1 0 Phospholipase A2 SIR2 PF02146.12 EMC88649.1 - 3.5e-51 173.4 0.0 4.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zf-C3HC4_3 PF13920.1 EMC88649.1 - 0.099 12.3 1.0 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Paxillin PF03535.8 EMC88650.1 - 1e-91 306.2 24.6 1e-91 306.2 17.1 1.7 2 0 0 2 2 2 1 Paxillin family LIM PF00412.17 EMC88650.1 - 1.2e-67 223.7 38.1 8e-19 67.4 1.5 4.4 4 0 0 4 4 4 4 LIM domain DUF164 PF02591.10 EMC88650.1 - 0.00095 18.9 0.5 0.00095 18.9 0.4 4.7 4 1 1 5 5 5 1 Putative zinc ribbon domain DUF1797 PF08796.5 EMC88650.1 - 0.19 11.6 0.3 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) Ion_trans PF00520.26 EMC88651.1 - 3.1e-19 69.0 1.5 4.5e-19 68.5 1.0 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 EMC88651.1 - 7.2e-18 64.2 0.0 1.3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 EMC88651.1 - 0.12 12.0 7.2 0.43 10.3 5.0 2.0 1 1 0 1 1 1 0 Ion channel Miff PF05644.6 EMC88652.1 - 1.5e-09 37.8 0.0 1.7e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff PAD_M PF08527.5 EMC88653.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Nsp1_C PF05064.8 EMC88654.1 - 7.3e-42 141.7 5.2 2.1e-41 140.2 3.6 1.7 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF4164 PF13747.1 EMC88654.1 - 0.028 14.5 1.5 0.028 14.5 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Prp18 PF02840.10 EMC88654.1 - 0.052 13.3 6.7 2.7 7.7 1.8 2.3 1 1 1 2 2 2 0 Prp18 domain AAA_32 PF13654.1 EMC88654.1 - 0.07 11.7 5.5 0.088 11.4 3.8 1.3 1 0 0 1 1 1 0 AAA domain CDC37_N PF03234.9 EMC88654.1 - 0.43 10.8 9.0 0.47 10.7 5.4 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Cauli_DNA-bind PF03310.8 EMC88654.1 - 0.59 9.9 3.8 4.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein BLOC1_2 PF10046.4 EMC88654.1 - 1.7 8.8 10.3 1.6 8.9 1.4 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 EMC88654.1 - 7.7 6.3 11.6 1.7 8.4 2.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 EMC88654.1 - 8.3 4.6 7.4 19 3.5 4.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Nsp1_C PF05064.8 EMC88655.1 - 2e-41 140.3 5.2 2e-41 140.3 3.6 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region DUF4164 PF13747.1 EMC88655.1 - 0.034 14.2 1.7 0.034 14.2 1.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) AAA_32 PF13654.1 EMC88655.1 - 0.1 11.2 5.5 0.13 10.9 3.8 1.3 1 0 0 1 1 1 0 AAA domain Prp18 PF02840.10 EMC88655.1 - 0.16 11.7 7.8 2.6 7.8 1.8 2.3 1 1 1 2 2 2 0 Prp18 domain Laminin_II PF06009.7 EMC88655.1 - 1.3 8.7 9.0 1.5 8.5 0.8 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 EMC88655.1 - 4 7.2 12.3 1.3 8.7 1.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EMC88655.1 - 4.5 7.4 11.3 1.7 8.8 1.5 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EMC88655.1 - 5.7 7.2 10.1 25 5.2 0.2 3.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 EMC88655.1 - 6.2 5.1 8.2 1.5 7.1 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Clat_adaptor_s PF01217.15 EMC88657.1 - 2e-54 183.1 1.3 2.3e-54 182.9 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ATX_III PF08098.6 EMC88658.1 - 0.85 9.5 10.3 21 5.0 0.1 4.0 3 0 0 3 3 3 0 Anemonia sulcata toxin III family ATP-synt_ab PF00006.20 EMC88660.1 - 1.1e-96 322.4 0.0 1.8e-96 321.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMC88660.1 - 7.2e-16 58.6 1.1 1.1e-15 58.0 0.7 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMC88660.1 - 7.8e-09 35.6 2.3 9.7e-09 35.3 0.3 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain C2 PF00168.25 EMC88663.1 - 5e-13 48.6 0.0 6.7e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain 7tm_4 PF13853.1 EMC88664.1 - 5.5e-60 201.3 9.1 1.2e-59 200.2 6.3 1.6 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC88664.1 - 8.4e-33 113.5 14.5 1.1e-32 113.1 10.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88664.1 - 0.0026 16.9 9.8 0.0026 16.9 6.8 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx bZIP_1 PF00170.16 EMC88666.1 - 5.6e-13 48.6 9.1 9.3e-13 47.9 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC88666.1 - 3e-11 42.9 7.7 5.6e-11 42.0 5.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC88666.1 - 1.4e-05 25.2 4.3 3.6e-05 23.9 3.0 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 EMC88666.1 - 0.0087 16.3 0.3 0.017 15.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF1843 PF08898.5 EMC88666.1 - 0.2 11.7 1.3 0.59 10.2 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DivIC PF04977.10 EMC88666.1 - 0.27 10.7 2.9 0.46 9.9 2.0 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EMC88666.1 - 0.94 9.2 4.4 1.9 8.2 3.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 EMC88666.1 - 1.3 8.8 5.4 1.8 8.3 2.2 2.2 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region LRR_8 PF13855.1 EMC88667.1 - 5.8e-56 186.1 36.8 1.6e-15 56.5 0.9 5.1 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EMC88667.1 - 2.4e-29 100.4 32.0 4.6e-05 22.9 0.6 7.9 1 1 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC88667.1 - 1.5e-23 79.2 29.7 0.052 13.5 0.0 11.8 12 0 0 12 12 12 9 Leucine Rich Repeat LRR_7 PF13504.1 EMC88667.1 - 6.8e-13 46.5 36.1 0.75 10.2 0.1 11.3 11 0 0 11 11 11 5 Leucine rich repeat LRR_9 PF14580.1 EMC88667.1 - 2.1e-09 37.2 1.9 0.00018 21.1 0.0 3.6 1 1 3 4 4 4 2 Leucine-rich repeat LRR_5 PF13306.1 EMC88667.1 - 4e-09 36.2 0.0 0.016 14.9 0.0 3.2 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMC88667.1 - 3.4e-06 26.5 30.1 3.8 7.8 0.0 10.9 9 2 1 10 10 10 1 Leucine Rich repeat LRRNT PF01462.13 EMC88667.1 - 0.036 13.5 1.6 0.071 12.6 1.1 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain WH2 PF02205.15 EMC88668.1 - 2.5e-10 39.6 0.6 2.5e-10 39.6 0.4 2.1 2 0 0 2 2 2 1 WH2 motif Peptidase_C69 PF03577.10 EMC88670.1 - 3.5e-09 36.0 0.0 4.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 EMC88670.1 - 0.044 13.2 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase GLTP PF08718.6 EMC88671.1 - 1.8e-34 118.9 0.1 6.2e-34 117.1 0.0 1.9 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PH PF00169.24 EMC88671.1 - 1.6e-07 31.4 0.1 1.2e-06 28.5 0.0 2.5 3 0 0 3 3 3 1 PH domain PH_8 PF15409.1 EMC88671.1 - 2.9e-05 24.0 0.0 0.00011 22.2 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EMC88671.1 - 0.0021 18.2 0.0 0.013 15.7 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Sec1 PF00995.18 EMC88671.1 - 0.0073 15.0 2.9 0.01 14.5 2.0 1.1 1 0 0 1 1 1 1 Sec1 family Collagen PF01391.13 EMC88672.1 - 1.1e-29 101.7 100.7 7.9e-10 38.1 19.8 4.6 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) DUF4215 PF13948.1 EMC88672.1 - 3.7e-05 23.8 5.3 3.7e-05 23.8 3.7 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4215) CN_hydrolase PF00795.17 EMC88673.1 - 2.3e-13 49.9 0.0 4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ank_2 PF12796.2 EMC88674.1 - 1.5e-195 634.2 53.1 2.5e-22 79.0 0.1 13.8 3 3 9 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 EMC88674.1 - 1.9e-194 620.7 76.1 6.2e-11 41.5 0.1 28.1 28 0 0 28 28 28 27 Ankyrin repeat Ank_4 PF13637.1 EMC88674.1 - 1.2e-157 509.8 49.3 1.6e-13 50.7 0.8 21.2 7 4 16 23 23 23 23 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC88674.1 - 5.5e-143 461.8 63.7 3e-11 43.1 0.2 22.5 7 5 16 23 23 23 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC88674.1 - 6.5e-126 397.4 63.9 1.5e-07 30.9 0.1 28.4 29 0 0 29 29 29 26 Ankyrin repeat Glycos_transf_2 PF00535.21 EMC88675.1 - 6.4e-27 94.2 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC88675.1 - 5.1e-21 74.9 0.2 8.6e-21 74.2 0.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EMC88675.1 - 3.8e-07 29.4 0.0 8.9e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC88675.1 - 5.7e-07 28.9 0.0 1.7e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EMC88675.1 - 1.7e-05 24.7 0.0 7e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 EMC88675.1 - 0.02 15.2 0.1 0.29 11.5 0.1 2.4 3 1 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like zf-CSL PF05207.8 EMC88676.1 - 1.4e-26 91.7 2.6 1.9e-26 91.3 1.8 1.2 1 0 0 1 1 1 1 CSL zinc finger Lar_restr_allev PF14354.1 EMC88676.1 - 0.058 13.7 0.5 0.083 13.2 0.4 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 EMC88676.1 - 0.089 12.7 0.6 0.18 11.7 0.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain NAD_binding_1 PF00175.16 EMC88677.1 - 2.7e-13 50.4 0.0 6.5e-13 49.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMC88677.1 - 1.8e-06 27.9 0.0 3.9e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF1707 PF08044.6 EMC88677.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) FAD_binding_6 PF00970.19 EMC88677.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Chibby PF14645.1 EMC88677.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Chibby family Raftlin PF15250.1 EMC88678.1 - 9.1e-195 647.4 2.2 1.1e-194 647.2 1.6 1.1 1 0 0 1 1 1 1 Raftlin DUF4177 PF13783.1 EMC88678.1 - 0.0063 16.1 0.0 0.46 10.1 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4177) PilO PF04350.8 EMC88678.1 - 0.066 13.0 0.1 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO TLP-20 PF06088.6 EMC88678.1 - 0.22 11.1 5.7 0.043 13.4 1.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RRM_1 PF00076.17 EMC88679.1 - 1e-14 53.8 0.4 1.6e-14 53.2 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC88679.1 - 7e-13 48.3 0.2 1.1e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC88679.1 - 3.8e-06 26.6 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI-PLC-X PF00388.14 EMC88680.1 - 9.1e-60 200.2 0.2 2.3e-59 198.9 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMC88680.1 - 2.6e-43 146.7 0.3 8.4e-43 145.1 0.2 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC88680.1 - 8.7e-27 92.9 0.2 2.1e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EMC88680.1 - 7e-17 61.0 0.0 1.5e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 EMC88680.1 - 4.8e-05 23.2 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 EMC88680.1 - 5.9e-05 23.2 0.1 0.00027 21.0 0.0 2.2 2 0 0 2 2 2 1 PH domain CUT PF02376.10 EMC88681.1 - 5.6e-45 151.0 11.2 7.3e-28 96.2 0.2 4.4 4 1 1 5 5 5 2 CUT domain Homeobox PF00046.24 EMC88681.1 - 4.6e-08 32.5 0.0 1.2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Homeobox domain PAT1 PF09770.4 EMC88681.1 - 0.015 13.6 30.3 0.0062 14.8 8.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HTH_3 PF01381.17 EMC88681.1 - 0.038 13.8 0.0 0.39 10.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix RuvA_C PF07499.8 EMC88681.1 - 0.044 13.9 0.3 0.33 11.1 0.1 2.6 3 0 0 3 3 3 0 RuvA, C-terminal domain PAS_9 PF13426.1 EMC88682.1 - 6.4e-20 71.4 0.0 2.2e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 PAS domain Ion_trans PF00520.26 EMC88682.1 - 1.7e-17 63.3 9.7 3.4e-17 62.3 6.7 1.6 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 EMC88682.1 - 3.3e-11 42.8 0.0 6.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 EMC88682.1 - 6.6e-11 41.7 0.5 6.6e-11 41.7 0.3 2.7 3 0 0 3 3 3 1 Ion channel PAS_3 PF08447.6 EMC88682.1 - 1.7e-05 24.7 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMC88682.1 - 0.00016 21.6 0.0 0.00087 19.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EMC88682.1 - 0.00019 21.2 0.0 0.00054 19.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold CENP-F_leu_zip PF10473.4 EMC88682.1 - 0.0029 17.4 1.7 2.5 7.9 1.0 2.6 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ion_trans_N PF08412.5 EMC88682.1 - 0.061 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal DUF1664 PF07889.7 EMC88682.1 - 0.076 12.8 1.4 0.19 11.5 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EMC88682.1 - 2.6 7.9 6.3 0.92 9.4 1.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EF-hand_7 PF13499.1 EMC88683.1 - 3.2e-12 46.3 6.1 7.7e-12 45.1 4.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC88683.1 - 6.9e-12 43.7 3.1 2.1e-06 26.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC88683.1 - 3.3e-10 38.9 4.9 6.6e-06 25.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EMC88683.1 - 1.1e-09 37.1 2.7 8.4e-06 24.9 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMC88683.1 - 9.6e-06 25.1 5.6 4e-05 23.1 3.4 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC88683.1 - 0.00034 20.6 0.3 0.00081 19.3 0.2 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF4483 PF14825.1 EMC88683.1 - 0.0022 17.7 0.0 0.22 11.1 0.0 3.1 1 1 3 4 4 4 1 Domain of unknown function (DUF4483) EF-hand_10 PF14788.1 EMC88683.1 - 0.014 15.0 5.2 0.018 14.6 0.9 2.9 2 1 1 3 3 3 0 EF hand Ras PF00071.17 EMC88684.1 - 2.6e-63 212.2 0.3 3e-63 212.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88684.1 - 4.4e-21 75.5 0.0 7.7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC88684.1 - 7.9e-13 48.0 0.0 9.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC88684.1 - 2.8e-06 26.6 0.0 3.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC88684.1 - 8.6e-05 22.0 0.1 0.0002 20.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC88684.1 - 0.00015 21.6 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC88684.1 - 0.065 12.4 0.1 0.17 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PP2C PF00481.16 EMC88685.1 - 1.3e-30 106.6 0.3 4e-24 85.3 0.0 3.6 3 1 1 4 4 4 2 Protein phosphatase 2C PCAF_N PF06466.6 EMC88686.1 - 3.2e-122 406.7 0.1 4.9e-122 406.1 0.0 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.20 EMC88686.1 - 8.7e-27 92.8 0.3 2e-26 91.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EMC88686.1 - 3.7e-11 43.0 0.3 8.8e-11 41.8 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMC88686.1 - 6.4e-09 35.7 0.1 1.7e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-met PF12874.2 EMC88687.1 - 2.8e-22 78.1 16.9 1.2e-08 34.8 1.8 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC88687.1 - 2.9e-18 65.4 15.3 1.4e-07 31.4 1.9 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC88687.1 - 7e-08 32.5 6.0 0.013 15.5 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EMC88687.1 - 1.1e-06 28.0 6.6 0.049 13.1 0.0 3.3 3 0 0 3 3 3 3 U1 zinc finger AKAP95 PF04988.7 EMC88687.1 - 2.2e-06 27.5 8.7 0.11 12.2 0.6 3.2 3 0 0 3 3 3 3 A-kinase anchoring protein 95 (AKAP95) OrfB_Zn_ribbon PF07282.6 EMC88687.1 - 0.0024 17.4 5.8 0.13 11.9 0.5 3.5 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zf-C2H2_4 PF13894.1 EMC88687.1 - 0.0061 16.8 9.0 1.7 9.1 1.0 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC88687.1 - 0.011 16.0 11.0 1.1 9.7 1.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-DBF PF07535.7 EMC88687.1 - 0.024 14.3 7.2 0.087 12.5 0.8 3.1 3 0 0 3 3 3 0 DBF zinc finger DUF3449 PF11931.3 EMC88687.1 - 0.13 11.7 8.7 0.73 9.3 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3449) zinc-ribbons_6 PF07191.7 EMC88687.1 - 0.61 9.9 5.8 8.5 6.2 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbons DUF493 PF04359.9 EMC88687.1 - 1.9 8.8 4.7 1.3 9.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Med3 PF11593.3 EMC88687.1 - 5.2 6.1 14.5 7.3 5.7 10.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-met PF12874.2 EMC88688.1 - 1.9e-08 34.2 0.6 4.2e-08 33.1 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC88688.1 - 4e-06 26.8 0.4 4e-06 26.8 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Endonuc-EcoRV PF09233.6 EMC88688.1 - 0.029 13.7 0.1 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease EcoRV Tox-GHH PF15636.1 EMC88689.1 - 2.2e-30 104.0 1.2 5.1e-30 102.9 0.8 1.7 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin Ten_N PF06484.7 EMC88689.1 - 6.3e-22 78.2 7.3 9.2e-22 77.6 5.0 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region EGF_2 PF07974.8 EMC88689.1 - 3.2e-17 62.3 153.1 0.0013 18.7 9.2 9.7 8 1 1 9 9 9 7 EGF-like domain NHL PF01436.16 EMC88689.1 - 1.9e-12 46.4 0.3 0.017 15.0 0.0 6.8 6 0 0 6 6 6 3 NHL repeat hEGF PF12661.2 EMC88689.1 - 1.5e-06 27.8 77.8 0.0047 16.9 2.4 9.3 8 0 0 8 8 8 7 Human growth factor-like EGF RHS_repeat PF05593.9 EMC88689.1 - 2.1e-06 27.7 34.1 0.013 15.6 0.4 8.5 8 1 1 9 9 9 4 RHS Repeat RHS PF03527.9 EMC88689.1 - 0.0002 21.0 0.3 0.0083 15.8 0.0 2.8 2 0 0 2 2 2 1 RHS protein SGL PF08450.7 EMC88689.1 - 0.00021 20.7 0.1 0.41 9.9 0.0 4.0 3 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region CarboxypepD_reg PF13620.1 EMC88689.1 - 0.0015 18.5 0.0 0.0053 16.7 0.0 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SH2 PF00017.19 EMC88690.1 - 2.3e-14 52.9 0.0 3.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 SH2 domain AraC_N PF06719.8 EMC88691.1 - 0.12 11.6 0.3 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus STAG PF08514.6 EMC88692.1 - 1.7e-47 159.9 0.2 7.3e-47 157.9 0.1 2.2 1 0 0 1 1 1 1 STAG domain Phage_DsbA PF11126.3 EMC88692.1 - 0.0082 16.1 0.6 7.2 6.7 0.0 3.2 2 0 0 2 2 2 2 Transcriptional regulator DsbA AdoHcyase_NAD PF00670.16 EMC88692.1 - 0.028 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain BIR PF00653.16 EMC88693.1 - 4.8e-64 212.7 16.4 8.1e-24 83.8 0.5 3.7 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 EMC88693.1 - 5.2e-14 51.6 9.6 5.2e-14 51.6 6.6 4.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC88693.1 - 3.2e-06 27.0 10.8 3.2e-06 27.0 7.5 4.1 6 0 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EMC88693.1 - 0.00023 20.6 2.1 0.00023 20.6 1.4 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 EMC88693.1 - 0.0032 17.1 8.0 0.0032 17.1 5.5 3.5 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC88693.1 - 0.018 14.8 8.1 0.018 14.8 5.6 3.4 4 0 0 4 4 4 0 Ring finger domain DUF581 PF04570.9 EMC88693.1 - 3.4 7.0 13.4 0.099 11.9 0.4 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF581) DUF2039 PF10217.4 EMC88693.1 - 9.7 6.2 10.7 0.51 10.3 2.9 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) Tho2 PF11262.3 EMC88694.1 - 2.8e-97 325.3 2.2 2.8e-97 325.3 1.5 3.4 3 1 2 5 5 5 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EMC88694.1 - 2.6e-34 116.8 0.2 1.8e-32 110.9 0.1 2.9 3 0 0 3 3 3 1 Transcription- and export-related complex subunit Lig_chan PF00060.21 EMC88695.1 - 2.5e-60 202.4 0.0 4.5e-60 201.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 EMC88695.1 - 1.6e-48 165.2 0.3 2.4e-48 164.7 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 EMC88695.1 - 2.1e-26 91.6 2.1 2.2e-26 91.5 0.2 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC88695.1 - 1e-25 90.3 0.0 1.9e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TLV_coat PF00429.14 EMC88696.1 - 3.8e-08 32.2 1.9 4.4e-08 32.0 1.3 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) PUA PF01472.15 EMC88698.1 - 7.4e-21 73.6 0.1 1.3e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 PUA domain Cullin PF00888.17 EMC88699.1 - 1.2e-177 592.0 20.3 1.7e-177 591.5 14.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMC88699.1 - 1.2e-27 95.4 1.0 1.2e-27 95.4 0.7 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain SecA_SW PF07516.8 EMC88699.1 - 0.00027 20.7 1.1 0.00027 20.7 0.7 3.3 4 0 0 4 4 4 1 SecA Wing and Scaffold domain TrmB PF01978.14 EMC88699.1 - 0.064 12.9 0.2 9.1 6.0 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Lamp PF01299.12 EMC88700.1 - 4.3e-106 354.5 12.8 9.5e-102 340.2 5.7 2.0 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) DUF368 PF04018.8 EMC88700.1 - 0.0055 15.9 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF368) FAM70 PF14967.1 EMC88701.1 - 3.4e-163 542.4 5.3 3.8e-163 542.3 3.7 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.1 EMC88701.1 - 0.0024 17.9 11.4 0.95 9.6 6.9 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) DUF1097 PF06496.6 EMC88701.1 - 9.9 5.9 11.1 3.5 7.4 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) Connexin PF00029.14 EMC88703.1 - 1.6e-36 124.5 1.5 1.6e-36 124.5 1.0 1.8 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 EMC88703.1 - 2.8e-31 107.1 1.8 2.8e-31 107.1 1.2 1.9 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Homeobox PF00046.24 EMC88704.1 - 1.8e-25 88.3 3.7 2e-25 88.1 2.6 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC88704.1 - 0.054 13.2 0.3 0.15 11.8 0.1 1.7 1 1 1 2 2 2 0 Homeobox KN domain Cytadhesin_P30 PF07271.6 EMC88705.1 - 9.9 5.3 57.2 11 5.2 6.4 3.6 1 1 3 4 4 4 0 Cytadhesin P30/P32 Peptidase_M14 PF00246.19 EMC88708.1 - 3.6e-58 197.3 0.0 9.6e-58 195.9 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.20 EMC88708.1 - 1.6e-22 79.7 0.1 2.9e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain CarboxypepD_reg PF13620.1 EMC88708.1 - 5.3e-14 52.0 0.1 9.9e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMC88708.1 - 4.1e-06 26.7 0.1 1.8e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) phage_tail_N PF08400.5 EMC88708.1 - 0.002 17.8 0.2 0.0067 16.1 0.2 1.8 1 1 0 1 1 1 1 Prophage tail fibre N-terminal Gelsolin PF00626.17 EMC88709.1 - 6.3e-13 48.2 0.0 2.2e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 Gelsolin repeat SH3_9 PF14604.1 EMC88710.1 - 1.9e-13 49.7 0.4 9.4e-13 47.5 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC88710.1 - 4.2e-13 48.4 0.2 4.2e-13 48.4 0.1 3.1 4 0 0 4 4 4 1 SH3 domain SH3_2 PF07653.12 EMC88710.1 - 7.5e-07 28.5 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ycf1 PF05758.7 EMC88710.1 - 0.067 10.9 2.2 0.065 10.9 1.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF1675 PF07897.6 EMC88710.1 - 1.5 8.6 7.9 2.1 8.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) U79_P34 PF03064.11 EMC88710.1 - 7 6.0 18.5 10 5.5 12.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF899 PF05988.7 EMC88711.1 - 0.34 10.3 7.6 0.58 9.5 0.1 3.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF899) HMG_box PF00505.14 EMC88712.1 - 1.1e-21 76.8 1.1 2e-21 75.9 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box CTNNB1_binding PF08347.6 EMC88712.1 - 5e-18 66.0 2.1 5e-18 66.0 1.5 2.7 2 1 1 3 3 3 1 N-terminal CTNNB1 binding HMG_box_2 PF09011.5 EMC88712.1 - 2.5e-08 34.1 1.5 4.1e-08 33.4 1.0 1.4 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EMC88712.1 - 0.0096 15.2 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Homeobox PF00046.24 EMC88717.1 - 2.3e-24 84.7 7.3 2.5e-24 84.6 5.1 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC88717.1 - 9.9e-05 21.9 0.6 0.00015 21.3 0.2 1.4 1 1 0 1 1 1 1 Homeobox KN domain CENP-B_N PF04218.8 EMC88717.1 - 0.00035 19.9 0.7 0.00068 19.0 0.5 1.7 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF2316 PF10078.4 EMC88717.1 - 0.0033 17.3 0.9 0.0033 17.3 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) Homez PF11569.3 EMC88717.1 - 0.025 13.6 0.1 0.027 13.5 0.1 1.1 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_Tnp_1 PF01527.15 EMC88717.1 - 0.072 13.0 0.3 0.11 12.4 0.2 1.6 1 1 0 1 1 1 0 Transposase Phage_CII PF05269.6 EMC88717.1 - 0.11 12.4 0.1 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CII protein HTH_26 PF13443.1 EMC88717.1 - 0.15 12.3 0.1 0.41 10.8 0.1 1.8 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain QLQ PF08880.6 EMC88717.1 - 0.26 10.7 2.5 0.22 10.9 0.7 1.9 2 1 0 2 2 2 0 QLQ PPDFL PF15060.1 EMC88718.1 - 0.056 13.4 1.6 0.098 12.6 1.1 1.5 1 1 0 1 1 1 0 Differentiation and proliferation regulator MIP-T3 PF10243.4 EMC88719.1 - 0.31 9.4 110.6 0.42 9.0 76.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MIP-T3 PF10243.4 EMC88720.1 - 0.25 9.7 115.8 0.47 8.8 80.2 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 I-set PF07679.11 EMC88721.1 - 9.9e-10 38.1 0.0 1.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC88721.1 - 3.9e-08 33.2 0.1 1.4e-07 31.5 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC88721.1 - 8.9e-08 32.1 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC88721.1 - 2e-06 27.6 1.8 0.0038 17.1 0.5 2.9 1 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC88721.1 - 1.3e-05 25.5 0.1 3.7e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.3 EMC88721.1 - 0.025 14.5 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 I-set PF07679.11 EMC88722.1 - 4.5e-12 45.6 0.0 1.5e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 EMC88722.1 - 8.1e-11 41.8 0.4 4.1e-06 26.6 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC88722.1 - 5.1e-09 36.1 0.3 4.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC88722.1 - 1.1e-07 31.8 0.1 2.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 EMC88722.1 - 0.00037 20.9 0.3 0.0011 19.4 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.3 EMC88722.1 - 0.0029 17.5 0.2 1.5 8.7 0.0 2.9 2 1 1 3 3 3 1 Natural killer cell receptor 2B4 Herpes_gE PF02480.11 EMC88722.1 - 0.075 11.2 0.0 0.21 9.8 0.0 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E I-set PF07679.11 EMC88724.1 - 1.1e-12 47.6 0.0 1.9e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 EMC88724.1 - 1.8e-10 40.7 0.1 4.5e-07 29.7 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC88724.1 - 3.1e-09 37.1 0.1 3.3e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC88724.1 - 1.5e-07 31.4 0.0 2.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC88724.1 - 0.00046 20.2 0.2 1 9.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain SEEK1 PF15357.1 EMC88724.1 - 0.061 13.2 0.0 0.34 10.7 0.0 2.0 1 1 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 V-set PF07686.12 EMC88725.1 - 3.5e-05 23.6 0.0 8.3e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.11 EMC88725.1 - 0.11 10.7 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TauD PF02668.11 EMC88726.1 - 4e-38 131.5 0.1 6.3e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EMC88726.1 - 0.0022 18.3 0.0 0.005 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 EMC88726.1 - 0.0037 16.2 0.0 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 CsiD Sprouty PF05210.8 EMC88727.1 - 8.9e-32 109.3 33.6 1.7e-31 108.4 23.3 1.5 1 0 0 1 1 1 1 Sprouty protein (Spry) 2OG-FeII_Oxy_2 PF13532.1 EMC88728.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 7tm_1 PF00001.16 EMC88729.1 - 7.9e-37 126.7 15.1 1.2e-36 126.1 10.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC88729.1 - 0.0015 17.7 16.8 0.0029 16.8 9.5 3.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC88729.1 - 0.0051 15.9 7.5 0.0071 15.4 4.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx RNA_pol_L_2 PF13656.1 EMC88730.1 - 5e-30 102.7 0.0 5.6e-30 102.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMC88730.1 - 2.7e-11 42.4 0.0 3.1e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Longin PF13774.1 EMC88731.1 - 9.1e-29 98.8 0.6 1.2e-28 98.4 0.4 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EMC88731.1 - 4.2e-12 45.5 0.7 6.9e-12 44.8 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin SLAIN PF15301.1 EMC88732.1 - 5.1e-110 368.1 50.6 1e-109 367.1 35.0 1.4 1 1 0 1 1 1 1 SLAIN motif-containing family DUF4095 PF13338.1 EMC88732.1 - 0.0048 17.0 0.1 3.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4095) 3Beta_HSD PF01073.14 EMC88733.1 - 2.7e-36 124.7 0.0 2.9e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC88733.1 - 1.3e-16 60.7 0.0 1.5e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC88733.1 - 0.00012 21.1 0.0 0.00014 20.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain EF-hand_1 PF00036.27 EMC88734.1 - 2.2e-33 110.9 11.0 1.3e-08 33.4 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC88734.1 - 1e-28 99.2 6.8 4.4e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC88734.1 - 7.8e-26 87.6 7.8 1.6e-08 33.7 0.0 4.6 4 2 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EMC88734.1 - 9.6e-24 82.7 8.7 9.2e-12 44.3 0.7 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EMC88734.1 - 2.9e-20 70.6 13.8 6e-06 25.3 0.0 4.5 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMC88734.1 - 2.3e-15 56.2 0.1 2e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC88734.1 - 1.4e-05 24.7 4.4 0.51 10.0 1.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand PMBR PF09373.5 EMC88734.1 - 0.0044 16.9 0.2 28 4.8 0.0 4.5 4 1 1 5 5 5 0 Pseudomurein-binding repeat SPARC_Ca_bdg PF10591.4 EMC88734.1 - 0.0066 16.4 0.1 2.8 7.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SRI PF08236.6 EMC88734.1 - 0.028 14.3 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain DUF21 PF01595.15 EMC88734.1 - 0.086 12.1 1.4 0.66 9.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 LETM1 PF07766.8 EMC88734.1 - 0.11 11.4 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 LETM1-like protein Toprim_2 PF13155.1 EMC88734.1 - 0.19 12.0 1.2 11 6.4 0.3 2.3 1 1 0 2 2 2 0 Toprim-like EF-hand_1 PF00036.27 EMC88735.1 - 4.8e-25 84.9 8.9 3.3e-08 32.2 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC88735.1 - 3.5e-20 71.9 4.1 8.8e-14 51.4 0.9 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC88735.1 - 6.8e-19 66.0 6.4 1.9e-05 24.1 0.0 4.7 4 2 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 EMC88735.1 - 6.9e-17 60.8 10.6 6.6e-11 41.6 1.6 4.1 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EMC88735.1 - 6.9e-12 44.1 15.9 8.1e-05 21.7 0.0 5.0 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.1 EMC88735.1 - 6.8e-11 41.9 0.3 1.3e-07 31.4 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 EMC88735.1 - 0.00046 19.8 0.4 0.00046 19.8 0.3 2.1 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC88735.1 - 0.14 12.1 0.4 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RNA_pol_Rpb4 PF03874.11 EMC88735.1 - 0.27 11.2 3.0 0.82 9.6 2.1 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb4 DJ-1_PfpI PF01965.19 EMC88736.1 - 4.3e-15 55.4 0.5 6.2e-15 54.9 0.4 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Sua5_yciO_yrdC PF01300.13 EMC88737.1 - 4.4e-34 117.2 0.0 6.2e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Sua5_yciO_yrdC PF01300.13 EMC88738.1 - 2e-28 98.8 0.1 4.1e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 Telomere recombination Grp1_Fun34_YaaH PF01184.14 EMC88738.1 - 2e-10 40.3 53.5 4.8e-08 32.5 12.6 3.3 3 0 0 3 3 3 3 GPR1/FUN34/yaaH family MmgE_PrpD PF03972.9 EMC88739.1 - 1e-58 198.6 0.0 1.2e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Sec3_C PF09763.4 EMC88740.1 - 1e-140 470.1 0.8 1.6e-140 469.5 0.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EMC88740.1 - 3.1e-25 87.8 1.2 6.5e-25 86.8 0.8 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH zf-C2H2 PF00096.21 EMC88741.1 - 3.4e-13 49.0 25.5 0.00017 21.6 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC88741.1 - 1.7e-09 37.5 10.2 9.7e-06 25.6 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC88741.1 - 5.4e-08 32.6 23.2 0.0071 16.5 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger DBD_Tnp_Mut PF03108.10 EMC88741.1 - 0.11 12.1 0.7 0.59 9.7 0.3 2.1 2 0 0 2 2 2 0 MuDR family transposase zf-C2H2_jaz PF12171.3 EMC88741.1 - 3.4 7.9 8.8 10 6.3 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMC88742.1 - 2.4e-14 52.7 22.7 7.3e-06 26.0 2.8 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC88742.1 - 1.9e-12 46.7 23.1 2.5e-08 33.7 0.9 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC88742.1 - 1.4e-08 34.5 19.5 0.0055 16.9 1.4 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMC88742.1 - 0.0029 17.7 3.0 1.4 9.1 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC88742.1 - 0.13 12.3 2.5 13 6.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC88742.1 - 2.7 8.0 7.1 0.29 11.0 0.5 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger Gtr1_RagA PF04670.7 EMC88743.1 - 2.4e-108 360.6 1.0 3.1e-108 360.2 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EMC88743.1 - 7.7e-09 35.1 0.0 1.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EMC88743.1 - 1.8e-08 33.8 0.1 3.1e-08 33.0 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC88743.1 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC88743.1 - 3.7e-05 24.2 0.1 0.00013 22.4 0.0 2.0 2 1 1 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EMC88743.1 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC88743.1 - 0.0042 16.3 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EMC88743.1 - 0.014 14.9 0.2 0.06 12.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EMC88743.1 - 0.022 13.6 1.7 0.23 10.3 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EMC88743.1 - 0.023 15.0 0.2 0.044 14.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EMC88743.1 - 0.035 13.6 0.3 0.063 12.8 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 EMC88743.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF4606 PF15379.1 EMC88744.1 - 2.6e-18 65.9 1.7 2.9e-18 65.8 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) zf-4CXXC_R1 PF10497.4 EMC88744.1 - 0.099 12.7 0.3 0.12 12.5 0.2 1.0 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 WTX PF09422.5 EMC88746.1 - 4.9e-63 213.7 18.4 4.6e-49 167.6 9.3 3.0 1 1 1 2 2 2 2 WTX protein Reovirus_M2 PF05993.7 EMC88746.1 - 0.13 10.0 0.0 0.19 9.4 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Ank_2 PF12796.2 EMC88747.1 - 4.2e-34 116.7 0.0 8.2e-16 58.1 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC88747.1 - 3.2e-33 111.8 5.0 1.3e-06 27.9 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EMC88747.1 - 5.7e-23 78.6 1.2 0.00011 22.1 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EMC88747.1 - 1.7e-21 75.7 3.7 0.00011 22.3 0.0 6.0 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC88747.1 - 2.4e-20 72.4 0.8 7.9e-10 38.9 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC88747.1 - 4.7e-07 29.5 0.4 1.2e-06 28.2 0.3 1.7 1 0 0 1 1 1 1 SOCS box Myotub-related PF06602.9 EMC88748.1 - 5.6e-143 475.9 0.0 7.1e-143 475.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EMC88748.1 - 0.00016 21.1 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Vps36_ESCRT-II PF11605.3 EMC88748.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase3 PF13350.1 EMC88748.1 - 0.0019 18.4 0.1 0.0055 16.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EMC88748.1 - 0.0033 16.8 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EMC88748.1 - 0.0036 16.8 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LIM PF00412.17 EMC88749.1 - 3.7e-13 49.3 3.3 6.5e-13 48.5 2.3 1.4 1 0 0 1 1 1 1 LIM domain TRAM_LAG1_CLN8 PF03798.11 EMC88750.1 - 2.2e-38 131.8 28.5 2.6e-38 131.6 19.7 1.1 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 EMC88750.1 - 0.0014 18.1 0.3 0.0025 17.3 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain NAD_Gly3P_dh_N PF01210.18 EMC88751.1 - 1.4e-56 190.5 0.1 7e-56 188.3 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EMC88751.1 - 6.8e-56 188.1 0.4 1e-55 187.5 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EMC88751.1 - 0.0012 19.2 1.3 0.051 14.0 0.1 3.3 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ASC PF00858.19 EMC88752.1 - 1.3e-171 571.0 0.1 1.7e-171 570.7 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel HLH PF00010.21 EMC88753.1 - 2.8e-18 65.3 0.4 5.1e-18 64.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Toxin_trans PF07952.7 EMC88753.1 - 0.014 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain DUF773 PF05600.7 EMC88753.1 - 0.068 11.9 0.1 0.082 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) PIP5K PF01504.13 EMC88754.1 - 4.2e-80 268.4 0.2 6e-80 267.9 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4542 PF15075.1 EMC88754.1 - 0.07 13.0 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) Frataxin_Cyay PF01491.11 EMC88755.1 - 3.2e-34 116.9 0.0 3.6e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain PDZ PF00595.19 EMC88756.1 - 8.6e-46 154.0 7.8 1.4e-15 57.2 0.2 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC88756.1 - 8.6e-16 57.6 3.6 0.00012 21.9 0.1 3.7 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 EMC88756.1 - 1e-11 44.5 0.1 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 EMC88756.1 - 2.3e-08 33.3 0.4 4.8e-07 29.1 0.0 3.2 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.23 EMC88756.1 - 0.0002 20.6 0.0 0.0029 16.9 0.0 2.9 2 0 0 2 2 2 1 SH3 domain C1q PF00386.16 EMC88757.1 - 1.1e-11 44.8 0.0 1.1e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 EMC88757.1 - 0.097 12.2 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family DnaJ PF00226.26 EMC88758.1 - 5e-15 54.9 0.0 5.2e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain DUF1387 PF07139.6 EMC88759.1 - 1e-25 91.0 7.8 2.6e-22 79.8 1.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1387) DUF1049 PF06305.6 EMC88761.1 - 0.13 11.7 2.5 0.2 11.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Integrin_alpha PF00357.15 EMC88761.1 - 0.19 11.5 1.8 0.34 10.7 1.3 1.4 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region adh_short PF00106.20 EMC88762.1 - 1.8e-13 50.7 0.0 2.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EMC88762.1 - 0.0046 16.1 0.0 0.0057 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) AsiA PF09010.5 EMC88762.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A adh_short_C2 PF13561.1 EMC88762.1 - 0.067 12.9 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2115 PF09888.4 EMC88762.1 - 0.088 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) SchA_CurD PF04486.7 EMC88763.1 - 0.079 12.7 0.2 0.86 9.4 0.0 2.1 2 0 0 2 2 2 0 SchA/CurD like domain SAP PF02037.22 EMC88764.1 - 1e-10 40.8 4.3 2.1e-09 36.6 1.0 2.5 2 0 0 2 2 2 2 SAP domain LETM1 PF07766.8 EMC88764.1 - 0.022 13.7 0.2 0.04 12.9 0.1 1.4 1 0 0 1 1 1 0 LETM1-like protein PBP_sp32 PF07222.7 EMC88764.1 - 5.5 6.0 12.1 0.87 8.7 5.3 1.8 1 1 1 2 2 2 0 Proacrosin binding protein sp32 Gasdermin PF04598.7 EMC88765.1 - 5.4e-37 127.6 0.1 5.9e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 Gasdermin family Guanylate_kin PF00625.16 EMC88766.1 - 7.2e-48 162.4 0.0 1.4e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.11 EMC88766.1 - 1.9e-29 101.0 1.5 8.2e-15 54.2 0.1 2.9 3 0 0 3 3 3 2 L27 domain SH3_2 PF07653.12 EMC88766.1 - 1.1e-11 43.9 0.2 3.7e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.19 EMC88766.1 - 8.4e-11 41.9 1.1 1.8e-10 40.8 0.7 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_9 PF14604.1 EMC88766.1 - 9.8e-07 28.2 0.0 2.8e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMC88766.1 - 1.8e-06 27.2 0.1 5e-06 25.8 0.1 1.8 2 0 0 2 2 2 1 SH3 domain PDZ_2 PF13180.1 EMC88766.1 - 2.7e-05 23.9 0.1 8.2e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 EMC88766.1 - 0.00072 19.2 0.1 0.01 15.6 0.1 2.7 2 1 0 2 2 2 1 Tricorn protease PDZ domain zf-RanBP PF00641.13 EMC88768.1 - 5.5e-08 31.7 2.1 9.1e-08 31.0 1.5 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Maf1 PF09174.5 EMC88769.1 - 1.7e-67 226.7 0.1 2e-67 226.4 0.1 1.1 1 0 0 1 1 1 1 Maf1 regulator DUF4201 PF13870.1 EMC88770.1 - 0.00046 19.6 21.1 0.00046 19.6 14.6 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.6 EMC88770.1 - 0.0091 15.3 2.2 0.0091 15.3 1.5 4.5 3 1 1 4 4 4 2 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 EMC88770.1 - 0.066 10.5 74.5 0.31 8.3 25.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 EMC88770.1 - 2 7.9 93.7 0.36 10.3 6.4 4.4 2 2 1 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 EMC88770.1 - 4.5 6.3 26.6 2.9 6.9 0.5 3.8 2 2 2 4 4 4 0 Reovirus sigma C capsid protein APG6 PF04111.7 EMC88770.1 - 5.1 6.0 81.8 0.017 14.1 9.2 4.1 2 2 2 4 4 4 0 Autophagy protein Apg6 Pellino PF04710.9 EMC88771.1 - 6.4e-227 753.0 0.3 7.2e-227 752.8 0.2 1.0 1 0 0 1 1 1 1 Pellino zf-C3HC4_3 PF13920.1 EMC88771.1 - 1.9e-05 24.2 3.5 0.04 13.5 0.4 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC88771.1 - 0.0017 18.3 7.9 0.27 11.2 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC88771.1 - 0.0035 17.0 1.9 0.28 10.9 0.2 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMC88771.1 - 0.19 11.5 14.7 1.5 8.6 2.2 3.1 2 1 0 2 2 2 0 Ring finger domain DUF2723 PF11028.3 EMC88773.1 - 1.2e-17 63.9 2.2 1.2e-17 63.9 1.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) TF_Otx PF03529.8 EMC88774.1 - 2.6e-37 126.9 14.5 2.6e-37 126.9 10.0 2.7 1 1 1 2 2 2 1 Otx1 transcription factor Homeobox PF00046.24 EMC88774.1 - 5.6e-22 77.1 2.2 8.7e-22 76.5 1.5 1.3 1 0 0 1 1 1 1 Homeobox domain Sec10 PF07393.6 EMC88775.1 - 3.2e-151 504.9 31.6 3e-149 498.4 16.4 3.5 2 1 0 2 2 2 1 Exocyst complex component Sec10 S-methyl_trans PF02574.11 EMC88775.1 - 0.035 13.4 0.2 0.079 12.2 0.1 1.5 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Phage_GP20 PF06810.6 EMC88775.1 - 1.2 8.5 13.1 0.032 13.6 2.9 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 Acetyltransf_1 PF00583.19 EMC88776.1 - 1.6e-17 63.2 0.0 2.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC88776.1 - 1.7e-10 40.8 0.1 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC88776.1 - 4.7e-09 35.8 0.0 8.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMC88776.1 - 5e-09 36.2 0.0 8.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMC88776.1 - 6e-07 29.4 0.0 9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMC88776.1 - 7.8e-06 26.1 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC88776.1 - 0.00037 20.3 0.0 0.00061 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EMC88776.1 - 0.029 13.2 0.1 0.04 12.7 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Ribosomal_60s PF00428.14 EMC88776.1 - 0.27 11.6 2.8 0.58 10.5 1.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4619 PF15398.1 EMC88778.1 - 9.8e-86 287.8 7.6 3.3e-84 282.8 5.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4619) EmrE PF13536.1 EMC88779.1 - 7.7e-10 38.9 0.7 7.7e-10 38.9 0.5 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMC88779.1 - 1.5e-06 28.2 5.0 1.5e-06 28.2 3.5 4.0 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 EMC88779.1 - 1.5e-05 24.0 11.1 2.3e-05 23.4 7.7 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EMC88779.1 - 0.0083 15.7 2.2 0.0083 15.7 1.6 2.7 3 0 0 3 3 3 1 Triose-phosphate Transporter family Mab-21 PF03281.9 EMC88780.1 - 6.5e-14 51.7 0.7 8.1e-13 48.1 0.5 2.1 1 1 0 1 1 1 1 Mab-21 protein zf-TRM13_CCCH PF11722.3 EMC88780.1 - 0.086 12.2 1.5 0.39 10.1 0.2 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein Nucleoplasmin PF03066.10 EMC88781.1 - 0.00027 20.4 8.9 0.0055 16.2 6.2 2.3 2 0 0 2 2 2 1 Nucleoplasmin Nop14 PF04147.7 EMC88781.1 - 0.0012 16.9 7.3 0.0014 16.6 5.1 1.1 1 0 0 1 1 1 1 Nop14-like family Drc1-Sld2 PF11719.3 EMC88781.1 - 0.0018 17.4 1.1 0.0022 17.1 0.7 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein CDC45 PF02724.9 EMC88781.1 - 0.0049 14.9 1.2 0.0062 14.6 0.8 1.3 1 0 0 1 1 1 1 CDC45-like protein TRAP_alpha PF03896.11 EMC88781.1 - 0.0083 15.1 3.2 0.014 14.3 2.2 1.4 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Plasmodium_Vir PF05795.6 EMC88781.1 - 0.025 13.7 0.2 0.054 12.6 0.1 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Voldacs PF03517.8 EMC88781.1 - 0.068 13.0 5.7 0.12 12.2 4.0 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling YqfQ PF14181.1 EMC88781.1 - 0.07 13.1 3.2 0.2 11.7 2.2 1.7 1 0 0 1 1 1 0 YqfQ-like protein CAF1A PF12253.3 EMC88781.1 - 0.15 12.2 14.2 5.9 7.0 8.6 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF1980 PF09323.5 EMC88781.1 - 0.19 11.4 0.1 9.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RRN3 PF05327.6 EMC88781.1 - 0.25 9.3 4.8 0.36 8.8 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.8 EMC88781.1 - 0.71 8.5 11.5 1.1 7.8 8.0 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 EMC88781.1 - 0.77 8.8 14.3 1.3 8.0 9.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PAXIP1_C PF15364.1 EMC88781.1 - 0.93 9.4 11.3 0.097 12.5 3.4 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Sigma70_ner PF04546.8 EMC88781.1 - 1.2 8.7 13.9 2.5 7.6 9.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region HSP90 PF00183.13 EMC88781.1 - 1.7 6.9 11.3 2.5 6.3 7.9 1.1 1 0 0 1 1 1 0 Hsp90 protein Pox_Ag35 PF03286.9 EMC88781.1 - 2.1 7.8 10.9 0.06 12.8 2.2 2.2 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Pox_RNA_Pol_19 PF05320.7 EMC88781.1 - 2.3 7.9 8.6 4.8 6.8 6.0 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Radial_spoke PF04712.7 EMC88781.1 - 3 6.5 13.7 4.7 5.8 9.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.1 EMC88781.1 - 5.4 6.6 12.4 0.95 9.1 3.9 2.9 4 0 0 4 4 4 0 FAM176 family Tim54 PF11711.3 EMC88781.1 - 7 5.1 8.2 7.7 4.9 5.4 1.4 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 EMC88781.1 - 8.3 6.1 7.3 16 5.1 5.1 1.5 1 1 0 1 1 1 0 DDHD domain bPH_6 PF10756.4 EMC88782.1 - 0.15 12.0 4.3 1.7 8.5 0.4 2.3 2 0 0 2 2 2 0 Bacterial PH domain KH_1 PF00013.24 EMC88783.1 - 2.2e-19 68.8 2.3 1.9e-14 53.0 0.3 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EMC88783.1 - 7.5e-10 38.2 0.2 2.7e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.1 EMC88783.1 - 0.021 14.5 1.2 0.039 13.6 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) KH_2 PF07650.12 EMC88783.1 - 0.027 14.0 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 KH domain Ras PF00071.17 EMC88784.1 - 1.6e-59 199.9 0.5 2e-59 199.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88784.1 - 2.8e-17 63.3 0.2 8e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC88784.1 - 1.7e-13 50.1 0.1 2.4e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC88784.1 - 1.4e-07 31.4 0.2 2.6e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC88784.1 - 7.4e-06 25.2 0.1 1.4e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.9 EMC88784.1 - 9.8e-06 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 EMC88784.1 - 2.5e-05 24.4 0.2 0.00071 19.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.5 EMC88784.1 - 3.7e-05 23.0 0.2 0.0016 17.7 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMC88784.1 - 0.00016 21.1 0.3 0.00083 18.8 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMC88784.1 - 0.00057 19.1 0.9 0.0063 15.7 0.6 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EMC88784.1 - 0.00068 18.8 0.4 0.0049 16.0 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMC88784.1 - 0.0015 18.4 0.0 0.0055 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EMC88784.1 - 0.0053 16.2 0.0 0.017 14.6 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EMC88784.1 - 0.0056 15.7 0.5 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_5 PF07728.9 EMC88784.1 - 0.007 16.1 0.1 0.029 14.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMC88784.1 - 0.0079 16.2 1.1 0.1 12.5 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EMC88784.1 - 0.014 14.5 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EMC88784.1 - 0.018 15.0 0.7 0.51 10.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain cobW PF02492.14 EMC88784.1 - 0.027 13.9 0.4 1.1 8.6 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 EMC88784.1 - 0.035 13.5 0.2 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EMC88784.1 - 0.036 13.6 0.4 0.16 11.5 0.0 2.1 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.22 EMC88784.1 - 0.051 13.8 1.8 0.18 12.0 1.2 2.0 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 EMC88784.1 - 0.054 13.1 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EMC88784.1 - 0.11 11.8 0.1 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EMC88784.1 - 0.12 12.6 0.1 0.39 11.0 0.0 1.9 1 1 0 2 2 2 0 AAA domain Robl_LC7 PF03259.12 EMC88785.1 - 3e-13 49.1 0.0 4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain ubiquitin PF00240.18 EMC88786.1 - 2.4e-13 49.2 0.2 3.8e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMC88786.1 - 6.6e-07 28.9 0.5 6.6e-07 28.9 0.3 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 EMC88786.1 - 0.00014 21.4 0.1 0.00025 20.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arm_2 PF04826.8 EMC88786.1 - 0.024 13.7 0.2 0.024 13.7 0.1 2.7 3 0 0 3 3 3 0 Armadillo-like Rad60-SLD_2 PF13881.1 EMC88786.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ComX PF05952.7 EMC88786.1 - 0.082 12.4 4.3 11 5.6 0.0 4.1 2 2 2 4 4 4 0 Bacillus competence pheromone ComX Herpes_Helicase PF02689.9 EMC88786.1 - 0.2 9.3 0.2 0.28 8.8 0.1 1.1 1 0 0 1 1 1 0 Helicase Kinesin-relat_1 PF12711.2 EMC88786.1 - 0.45 10.9 14.2 8.1 6.9 1.2 4.3 2 1 1 3 3 3 0 Kinesin motor Clathrin-link PF09268.5 EMC88786.1 - 6.2 5.9 9.1 35 3.5 0.2 3.9 3 0 0 3 3 3 0 Clathrin, heavy-chain linker Drf_FH1 PF06346.7 EMC88787.1 - 2.1 7.8 93.2 18 4.8 23.2 3.4 1 1 1 2 2 2 0 Formin Homology Region 1 G-patch PF01585.18 EMC88788.1 - 2.4e-06 27.2 1.6 3.2e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 G-patch domain MDMPI_C PF07398.6 EMC88788.1 - 0.06 13.9 0.4 0.11 13.0 0.3 1.5 1 0 0 1 1 1 0 MDMPI C-terminal domain UvrD-helicase PF00580.16 EMC88788.1 - 0.37 10.0 8.1 0.49 9.6 5.6 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PLRV_ORF5 PF01690.12 EMC88788.1 - 4.7 6.2 23.2 6.7 5.7 16.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein YjeF_N PF03853.10 EMC88789.1 - 2.2e-37 128.2 0.0 2.6e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus wnt PF00110.14 EMC88790.1 - 2.4e-119 398.1 24.6 2.7e-119 397.9 17.0 1.0 1 0 0 1 1 1 1 wnt family VWA_N PF08399.6 EMC88791.1 - 2.2e-41 141.3 0.3 5.4e-41 140.0 0.2 1.7 1 0 0 1 1 1 1 VWA N-terminal Cache_1 PF02743.13 EMC88791.1 - 4.9e-30 102.9 0.3 5.3e-29 99.6 0.0 2.7 3 0 0 3 3 3 1 Cache domain VWA_2 PF13519.1 EMC88791.1 - 4.8e-16 59.3 0.0 8.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMC88791.1 - 1.3e-15 57.4 0.0 2.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMC88791.1 - 5.4e-13 49.0 0.0 9.9e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMC88791.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein LRR_8 PF13855.1 EMC88792.1 - 3.2e-24 84.4 15.8 9e-15 54.1 2.6 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC88792.1 - 1.4e-12 46.9 17.6 3.5e-06 26.4 1.9 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC88792.1 - 1.8e-07 30.2 17.0 0.01 15.7 0.2 5.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.1 EMC88792.1 - 2.8e-07 30.2 0.1 2.3e-06 27.3 0.3 2.0 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC88792.1 - 6.9e-05 22.4 4.0 0.054 13.0 0.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EMC88792.1 - 0.00012 21.8 7.2 0.8 9.9 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRRNT PF01462.13 EMC88792.1 - 0.0038 16.6 1.5 0.0038 16.6 1.0 2.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EMC88792.1 - 0.014 15.4 16.7 0.17 12.1 0.1 5.5 7 0 0 7 7 7 0 Leucine rich repeat DUF2763 PF10961.3 EMC88793.1 - 1.4e-27 95.8 0.3 1.7e-27 95.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) Actin PF00022.14 EMC88794.1 - 4.1e-31 107.7 0.0 5.6e-30 104.0 0.0 2.1 1 1 0 1 1 1 1 Actin GMC_oxred_N PF00732.14 EMC88795.1 - 3.6e-96 321.7 0.0 4.8e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMC88795.1 - 4.3e-41 140.5 0.0 7.2e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMC88795.1 - 0.00011 21.1 0.0 0.32 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EMC88795.1 - 0.0013 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMC88795.1 - 0.0013 17.7 0.2 0.073 11.9 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMC88795.1 - 0.024 14.6 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC88795.1 - 0.036 14.1 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMC88795.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ion_trans PF00520.26 EMC88796.1 - 2e-210 693.1 82.1 8.2e-65 217.8 6.6 4.6 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.6 EMC88796.1 - 3.6e-19 67.6 1.9 1.2e-18 66.0 1.3 2.0 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.7 EMC88796.1 - 6.7e-09 34.6 5.3 6.7e-09 34.6 3.7 9.1 7 3 1 8 8 8 5 Polycystin cation channel DCP1 PF06058.8 EMC88797.1 - 1.3e-34 118.8 0.1 2.4e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family Transketolase_N PF00456.16 EMC88798.1 - 1.7e-81 273.6 0.0 2.9e-81 272.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMC88798.1 - 6.8e-42 142.9 0.0 1.3e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMC88798.1 - 3.2e-28 98.1 1.1 5.1e-28 97.4 0.3 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.15 EMC88798.1 - 2e-08 33.3 0.0 7.8e-08 31.3 0.0 1.8 1 1 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EMC88798.1 - 2.5e-06 27.1 0.1 9.9e-05 21.9 0.0 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EMC88798.1 - 9.3e-06 24.7 0.0 0.00067 18.6 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EMC88798.1 - 0.0036 15.9 0.1 0.014 13.9 0.0 1.8 1 1 1 2 2 2 1 XFP N-terminal domain Muskelin_N PF06588.6 EMC88799.1 - 4.6e-89 297.3 0.3 7.3e-89 296.7 0.2 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 EMC88799.1 - 6.2e-24 83.5 9.1 2.9e-11 43.2 0.0 5.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC88799.1 - 1.9e-21 75.5 11.8 1.6e-05 24.5 0.2 7.3 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EMC88799.1 - 8.1e-18 63.6 11.8 2.6e-05 23.6 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EMC88799.1 - 5.4e-15 54.8 4.7 0.0066 16.5 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EMC88799.1 - 5.8e-13 48.4 10.3 0.0044 16.9 0.0 6.1 6 1 0 6 6 6 4 Kelch motif F5_F8_type_C PF00754.20 EMC88799.1 - 1.2e-06 28.3 0.0 3.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.10 EMC88799.1 - 1.1e-05 24.9 12.3 0.086 12.6 0.1 6.1 6 1 1 7 7 7 2 Kelch motif Sad1_UNC PF07738.8 EMC88799.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal CD34_antigen PF06365.7 EMC88800.1 - 2e-65 220.2 2.3 2.2e-65 220.0 1.6 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family IncA PF04156.9 EMC88800.1 - 0.0011 18.6 0.1 0.0068 16.0 0.0 2.0 2 0 0 2 2 2 1 IncA protein EphA2_TM PF14575.1 EMC88800.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LSPR PF06049.7 EMC88801.1 - 0.72 9.5 35.9 8.7 6.2 0.2 8.5 8 0 0 8 8 8 0 Coagulation Factor V LSPD Repeat KA1 PF02149.14 EMC88803.1 - 4.3e-19 67.6 0.0 5.6e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Kinase associated domain 1 HECT PF00632.20 EMC88804.1 - 6.9e-27 94.4 0.0 7.4e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Alpha_kinase PF02816.13 EMC88806.1 - 2e-43 148.2 0.1 2.8e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family Tsg PF04668.7 EMC88806.1 - 0.0096 16.1 0.5 0.015 15.5 0.3 1.4 1 0 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region Ig_2 PF13895.1 EMC88807.1 - 5.5e-25 87.3 0.1 2.6e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Peptidase_C14 PF00656.17 EMC88807.1 - 7.8e-19 68.3 0.0 1.1e-17 64.5 0.0 2.1 1 1 0 1 1 1 1 Caspase domain Ig_3 PF13927.1 EMC88807.1 - 2.7e-18 66.1 2.8 2.8e-08 34.1 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC88807.1 - 6.9e-15 54.9 1.2 6.3e-07 29.4 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC88807.1 - 8.5e-15 54.3 0.1 7.9e-06 25.6 0.0 3.0 2 2 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 EMC88807.1 - 2.2e-09 37.1 2.0 0.014 15.2 0.1 4.0 2 2 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC88807.1 - 0.0036 17.1 0.1 0.68 9.8 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Death PF00531.17 EMC88807.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 Death domain Trehalose_PPase PF02358.11 EMC88807.1 - 0.12 11.2 0.4 0.23 10.3 0.0 1.6 2 0 0 2 2 2 0 Trehalose-phosphatase Glyco_transf_21 PF13506.1 EMC88807.1 - 0.14 11.4 0.1 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 21 Peptidase_S24 PF00717.18 EMC88808.1 - 2.3e-11 43.1 0.1 3.8e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF504 PF04457.7 EMC88808.1 - 0.066 13.3 1.3 0.13 12.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF504) Lectin_leg-like PF03388.8 EMC88809.1 - 6.1e-79 264.3 0.1 8.1e-79 263.9 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EMC88809.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Legume lectin domain Med30 PF11315.3 EMC88809.1 - 0.047 13.8 3.1 7.1 6.7 0.0 2.8 3 0 0 3 3 3 0 Mediator complex subunit 30 OmpH PF03938.9 EMC88809.1 - 0.33 10.8 9.4 0.98 9.3 6.5 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 EMC88809.1 - 0.47 9.3 3.0 0.7 8.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-SNARE PF05008.10 EMC88809.1 - 0.59 10.3 5.8 0.19 11.9 0.7 2.7 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Cytochrom_B562 PF07361.6 EMC88809.1 - 0.68 10.3 3.9 2.3 8.6 0.4 2.5 2 1 0 2 2 2 0 Cytochrome b562 ApoLp-III PF07464.6 EMC88809.1 - 0.91 9.5 5.0 0.92 9.5 0.4 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Kinetocho_Slk19 PF12709.2 EMC88809.1 - 5.1 7.2 8.6 3.6 7.7 0.1 2.9 3 0 0 3 3 3 0 Central kinetochore-associated Synaphin PF05835.7 EMC88810.1 - 4.9e-24 85.0 11.2 6.7e-24 84.6 7.8 1.2 1 0 0 1 1 1 1 Synaphin protein DUF4449 PF14613.1 EMC88810.1 - 4.6 7.1 9.3 0.57 10.0 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Homeobox PF00046.24 EMC88811.1 - 1.3e-24 85.5 4.6 2.3e-24 84.7 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 EMC88811.1 - 7.8e-11 41.1 0.4 1.3e-10 40.4 0.3 1.4 1 0 0 1 1 1 1 OAR domain Myosin_tail_1 PF01576.14 EMC88812.1 - 0 1100.1 286.1 0 1081.2 152.6 3.2 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 EMC88812.1 - 1.8e-274 912.1 0.7 1.8e-274 912.1 0.5 3.5 4 1 1 5 5 5 1 Myosin head (motor domain) Filament PF00038.16 EMC88812.1 - 0.00021 20.8 237.3 0.0015 18.1 12.0 8.4 1 1 5 6 6 6 4 Intermediate filament protein Reo_sigmaC PF04582.7 EMC88812.1 - 0.0051 16.0 76.9 0.008 15.3 2.5 9.1 1 1 7 10 10 10 6 Reovirus sigma C capsid protein IQ PF00612.22 EMC88812.1 - 0.032 13.8 3.8 0.098 12.3 0.8 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif CTD_bind PF04818.8 EMC88814.1 - 2e-20 72.7 1.7 2.5e-20 72.4 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Acetyltransf_11 PF13720.1 EMC88814.1 - 0.074 13.2 0.2 23 5.2 0.0 2.8 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Het-C PF07217.6 EMC88814.1 - 0.078 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C PRP3 PF08572.5 EMC88815.1 - 5.3e-43 146.9 2.2 5.1e-25 88.1 0.0 3.6 4 1 0 4 4 4 2 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EMC88815.1 - 2.4e-36 124.2 1.3 2.4e-36 124.2 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PWI PF01480.12 EMC88815.1 - 2e-16 59.8 0.0 5.6e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 PWI domain LRR_4 PF12799.2 EMC88817.1 - 8.2e-17 60.4 13.5 1.9e-11 43.3 2.8 2.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC88817.1 - 3.9e-13 48.9 14.1 6e-09 35.5 2.6 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 EMC88817.1 - 2.5e-10 40.2 0.4 3.3e-10 39.8 0.3 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EMC88817.1 - 1.4e-08 33.5 9.4 0.062 13.5 0.1 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EMC88817.1 - 1.5e-08 33.8 13.8 3.6e-05 23.3 0.2 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 EMC88817.1 - 5e-06 25.8 10.7 0.025 14.5 0.1 4.9 4 1 1 5 5 5 2 Leucine Rich Repeat BUD22 PF09073.5 EMC88817.1 - 7.4e-05 21.9 7.2 8.8e-05 21.7 5.0 1.1 1 0 0 1 1 1 1 BUD22 PH PF00169.24 EMC88818.1 - 9.8e-11 41.7 0.7 2.1e-10 40.7 0.5 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EMC88818.1 - 0.001 19.2 0.7 0.013 15.6 0.5 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EMC88818.1 - 0.002 18.3 0.6 0.002 18.3 0.4 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain OTU PF02338.14 EMC88819.1 - 1.3e-27 96.7 0.3 3.2e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease MIB_HERC2 PF06701.8 EMC88819.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 Mib_herc2 RRM_1 PF00076.17 EMC88820.1 - 5.5e-41 138.0 0.0 1.4e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC88820.1 - 3.1e-26 91.1 0.0 5.4e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC88820.1 - 6.6e-21 73.9 0.0 2.7e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC88820.1 - 0.0013 18.4 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 EMC88820.1 - 0.0038 16.6 0.1 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain RGM_N PF06535.7 EMC88821.1 - 4.8e-63 211.9 0.1 5.7e-63 211.7 0.1 1.1 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus RGM_C PF06534.8 EMC88821.1 - 7.3e-08 31.8 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus Collagen PF01391.13 EMC88822.1 - 0.0021 17.5 60.4 1.5e+04 -41.2 41.9 6.3 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Sad1_UNC PF07738.8 EMC88823.1 - 2.2e-25 89.0 0.0 9.7e-25 86.9 0.0 1.8 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Herpes_BLLF1 PF05109.8 EMC88823.1 - 0.042 11.8 1.3 0.046 11.6 0.9 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) HEAT PF02985.17 EMC88826.1 - 4.3e-42 138.4 19.2 6.4e-05 22.6 0.0 11.5 11 0 0 11 11 11 10 HEAT repeat HEAT_2 PF13646.1 EMC88826.1 - 9.4e-31 105.9 3.4 9.7e-10 38.6 0.0 6.2 2 1 4 6 6 6 5 HEAT repeats Vac14_Fab1_bd PF12755.2 EMC88826.1 - 1.3e-10 41.4 0.3 0.16 12.3 0.0 6.3 3 2 3 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC88826.1 - 5.5e-10 39.4 6.6 1.9 9.0 0.0 7.9 6 3 3 9 9 9 4 HEAT-like repeat CLASP_N PF12348.3 EMC88826.1 - 0.0042 16.4 0.5 2.8 7.2 0.0 4.5 3 2 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.2 EMC88826.1 - 0.023 14.5 0.1 7.7 6.3 0.0 3.6 2 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 EMC88826.1 - 0.059 13.8 0.0 31 5.4 0.0 4.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF3989 PF13150.1 EMC88826.1 - 0.12 11.8 0.0 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Gag_p30 PF02093.11 EMC88827.1 - 1e-24 86.9 0.1 1.1e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Exo_endo_phos PF03372.18 EMC88828.1 - 8.9e-26 91.3 0.1 1.2e-25 90.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CALCOCO1 PF07888.6 EMC88828.1 - 1.9e-08 33.0 0.3 2.6e-08 32.6 0.2 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Sep15_SelM PF08806.6 EMC88829.1 - 5.9e-13 48.3 0.0 7.6e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Sep15/SelM redox domain CH PF00307.26 EMC88830.1 - 1.7e-19 69.8 0.0 3.5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Smoothelin PF12510.3 EMC88830.1 - 1.7e-17 62.9 13.0 6.8e-17 61.0 9.0 2.1 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein CAMSAP_CH PF11971.3 EMC88830.1 - 4e-09 36.0 0.0 9.1e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain Ub-Mut7C PF14451.1 EMC88830.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF572 PF04502.8 EMC88830.1 - 0.96 8.6 28.1 1.5 7.9 19.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.4 EMC88830.1 - 4.7 5.3 20.0 5.8 5.0 13.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Smoothelin PF12510.3 EMC88831.1 - 1.1e-20 73.2 23.1 3.7e-15 55.5 6.8 2.3 2 0 0 2 2 2 2 Smoothelin cytoskeleton protein DUF3663 PF12404.3 EMC88831.1 - 0.2 11.4 3.2 0.45 10.3 0.2 2.3 2 1 0 2 2 2 0 Peptidase HATPase_c_3 PF13589.1 EMC88832.1 - 1e-24 86.7 0.0 2.9e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.10 EMC88832.1 - 1.8e-16 59.5 4.4 4.1e-16 58.4 3.1 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger RhoGAP PF00620.22 EMC88833.1 - 5.6e-35 120.2 0.0 6.1e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain XFP_C PF09363.5 EMC88833.1 - 0.035 13.5 0.1 0.05 13.0 0.1 1.1 1 0 0 1 1 1 0 XFP C-terminal domain Phage_int_SAM_3 PF14659.1 EMC88833.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF2189 PF09955.4 EMC88834.1 - 0.12 12.3 3.4 0.26 11.2 2.4 1.5 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Pellino PF04710.9 EMC88835.1 - 2.9e-238 790.4 0.1 3.2e-238 790.2 0.1 1.0 1 0 0 1 1 1 1 Pellino zf-C3HC4_3 PF13920.1 EMC88835.1 - 0.00078 19.0 6.2 0.5 10.0 0.2 3.0 2 2 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC88835.1 - 0.0012 18.7 6.6 0.028 14.4 0.0 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC88835.1 - 0.0059 16.3 0.8 6.6 6.5 0.0 3.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.1 EMC88835.1 - 0.26 11.1 12.5 0.9 9.4 1.3 3.2 3 1 0 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.1 EMC88835.1 - 3.2 7.3 10.9 5.8 6.5 0.1 3.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EMC88835.1 - 4.5 7.4 7.1 0.82 9.8 0.2 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC88835.1 - 6.1 6.6 10.2 0.57 9.9 0.1 3.4 2 2 0 2 2 2 0 zinc-RING finger domain Vps54 PF07928.7 EMC88836.1 - 4.5e-60 201.6 4.3 7.2e-60 201.0 0.7 3.0 3 0 0 3 3 3 1 Vps54-like protein DUF2450 PF10475.4 EMC88836.1 - 3e-09 36.2 7.4 3e-09 36.2 5.1 2.9 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) UDPGP PF01704.13 EMC88837.1 - 1e-192 640.3 0.6 1.5e-192 639.7 0.4 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EMC88837.1 - 0.008 14.7 0.2 1.2 7.6 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4301) Ldh_1_C PF02866.13 EMC88838.1 - 1.6e-50 171.2 0.0 4.3e-50 169.8 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EMC88838.1 - 5.4e-39 133.2 0.4 1e-38 132.3 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain DUF3312 PF11768.3 EMC88839.1 - 2e-246 818.4 0.9 2.3e-246 818.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) NT-C2 PF10358.4 EMC88840.1 - 9.1e-29 99.7 0.4 2e-28 98.6 0.3 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3585 PF12130.3 EMC88840.1 - 1.3e-23 83.4 9.9 1.3e-23 83.4 6.8 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3585) CH PF00307.26 EMC88840.1 - 6.3e-18 64.7 0.0 1.8e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC88840.1 - 4.2e-08 32.7 0.2 2.3e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain Isochorismatase PF00857.15 EMC88840.1 - 0.1 12.5 0.7 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 Isochorismatase family DUF4287 PF14117.1 EMC88840.1 - 0.16 11.7 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Baculo_19 PF04798.7 EMC88840.1 - 0.18 11.2 0.7 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 Baculovirus 19 kDa protein conserved region Transmemb_17 PF09799.4 EMC88841.1 - 2.8e-34 117.7 13.9 4.5e-34 117.0 9.6 1.3 1 0 0 1 1 1 1 Predicted membrane protein DUF3043 PF11241.3 EMC88841.1 - 4 6.9 10.6 1.3 8.6 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) EGF_CA PF07645.10 EMC88842.1 - 3.9e-10 39.5 6.7 7e-10 38.7 4.7 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.2 EMC88842.1 - 3.5e-05 23.6 4.4 6.1e-05 22.8 3.1 1.4 1 0 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.2 EMC88842.1 - 0.00013 21.6 3.1 0.00022 20.9 2.1 1.5 1 0 0 1 1 1 1 MSP1 EGF domain 1 DUF3844 PF12955.2 EMC88842.1 - 0.00081 19.4 0.4 0.0012 18.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF PF00008.22 EMC88842.1 - 0.0015 18.4 6.1 0.0027 17.6 2.8 2.3 3 0 0 3 3 3 1 EGF-like domain FXa_inhibition PF14670.1 EMC88842.1 - 0.14 12.2 4.9 0.79 9.9 3.6 2.0 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EMC88842.1 - 6.2 6.5 6.9 0.28 10.8 0.9 1.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_2 PF07974.8 EMC88842.1 - 9.6 6.4 9.2 0.84 9.8 3.2 1.6 2 0 0 2 2 2 0 EGF-like domain Galactosyl_T PF01762.16 EMC88843.1 - 1.2e-42 145.7 0.0 2e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC88843.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EMC88843.1 - 0.0084 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 CDP-OH_P_transf PF01066.16 EMC88844.1 - 1.1e-13 51.3 10.2 3.8e-13 49.5 7.1 2.0 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MCM PF00493.18 EMC88845.1 - 2.6e-126 420.9 0.0 3.3e-126 420.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EMC88845.1 - 2.8e-08 33.1 0.0 5.6e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMC88845.1 - 1.2e-07 31.5 0.0 2.9e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.1 EMC88845.1 - 7.3e-05 23.2 1.4 0.00071 20.0 0.1 2.9 3 0 0 3 3 3 1 MCM N-terminal domain AAA_3 PF07726.6 EMC88845.1 - 0.00042 19.9 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EMC88845.1 - 0.001 18.5 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 EMC88845.1 - 0.0076 16.4 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC88845.1 - 0.021 14.9 0.0 0.069 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMC88845.1 - 0.032 13.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 EMC88845.1 - 0.079 12.9 2.5 0.86 9.5 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain Gcd10p PF04189.8 EMC88846.1 - 4.2e-76 255.9 0.2 4.2e-76 255.9 0.1 2.3 1 1 0 2 2 2 1 Gcd10p family INTS5_C PF14838.1 EMC88846.1 - 0.05 11.9 0.1 0.079 11.2 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Granin PF01271.12 EMC88847.1 - 2.6e-27 95.8 12.8 2.7e-27 95.7 8.9 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) DUF4521 PF15021.1 EMC88848.1 - 1.2e-66 224.2 2.2 3.1e-66 222.8 1.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4521) Collagen PF01391.13 EMC88849.1 - 1.6e-35 120.4 218.3 5.5e-09 35.4 19.8 8.8 5 2 3 8 8 8 7 Collagen triple helix repeat (20 copies) Fz PF01392.17 EMC88849.1 - 7.5e-17 61.7 0.4 1.1e-16 61.2 0.3 1.2 1 0 0 1 1 1 1 Fz domain Laminin_G_3 PF13385.1 EMC88849.1 - 1.2e-06 28.8 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF2341 PF10102.4 EMC88849.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) KH_1 PF00013.24 EMC88850.1 - 2.6e-41 139.0 13.8 1.5e-17 62.9 0.2 4.1 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EMC88850.1 - 3.2e-29 100.0 21.8 1.2e-13 50.3 0.3 4.0 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EMC88850.1 - 7.3e-11 41.4 1.8 1.6e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 KH domain KH_4 PF13083.1 EMC88850.1 - 3.9e-05 23.2 0.6 2.1 8.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMC88850.1 - 0.0017 18.1 2.6 1.1 9.1 0.1 2.7 3 0 0 3 3 3 2 NusA-like KH domain VWA PF00092.23 EMC88851.1 - 7e-84 279.9 7.2 9.4e-35 119.9 0.1 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.13 EMC88851.1 - 4.7e-52 173.3 210.0 3.9e-10 39.1 15.7 7.3 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 EMC88851.1 - 4.1e-31 108.3 1.5 2.9e-09 37.2 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain FTCD PF02971.9 EMC88853.1 - 1.7e-81 270.9 0.1 2.9e-81 270.2 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_N PF07837.7 EMC88853.1 - 1.2e-74 249.6 0.0 1.9e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.7 EMC88853.1 - 3.4e-63 212.4 0.4 5.4e-63 211.7 0.3 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Keratin PF02422.11 EMC88854.1 - 7.9e-33 112.3 12.8 8.5e-33 112.2 8.9 1.0 1 0 0 1 1 1 1 Keratin SAC3_GANP PF03399.11 EMC88855.1 - 6.9e-56 189.0 2.3 1.4e-55 187.9 1.6 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMC88855.1 - 1.7e-05 24.6 0.0 5.3e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RRM_6 PF14259.1 EMC88855.1 - 0.0021 18.0 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC88855.1 - 0.0088 15.6 0.0 0.028 14.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0158 PF03682.8 EMC88855.1 - 0.024 14.2 0.8 0.091 12.3 0.4 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0158) Tobravirus_2B PF05271.6 EMC88855.1 - 0.064 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Tobravirus 2B protein SAC3 PF12209.3 EMC88855.1 - 0.09 12.9 3.8 0.48 10.5 0.7 3.2 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain O-FucT PF10250.4 EMC88856.1 - 4.6e-84 282.5 0.0 5.7e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SNF2_N PF00176.18 EMC88858.1 - 1.9e-22 79.4 0.0 2.2e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EMC88858.1 - 0.0014 18.7 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EMC88858.1 - 0.0015 18.4 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC88858.1 - 0.06 12.8 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EMC88858.1 - 0.066 12.1 0.0 0.066 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.10 EMC88858.1 - 0.085 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 DEAD_2 DUF1086 PF06461.6 EMC88861.1 - 1.3e-23 83.3 0.0 1.5e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) PWWP PF00855.12 EMC88864.1 - 5.1e-19 68.2 0.3 1.3e-18 66.9 0.2 1.7 1 0 0 1 1 1 1 PWWP domain DNA_methylase PF00145.12 EMC88864.1 - 8.8e-16 57.9 0.0 3.2e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase GST_C_2 PF13410.1 EMC88865.1 - 2.1e-05 24.2 0.0 7.2e-05 22.6 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC88865.1 - 0.00028 20.8 0.1 0.00059 19.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4208 PF13907.1 EMC88865.1 - 0.0026 17.9 0.8 0.017 15.3 0.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4208) GST_C_3 PF14497.1 EMC88865.1 - 0.03 14.7 0.0 0.069 13.6 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP-gua_PtransN PF02807.10 EMC88865.1 - 0.12 12.5 0.1 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain FliT PF05400.8 EMC88865.1 - 0.31 11.4 1.6 0.62 10.5 1.1 1.5 1 0 0 1 1 1 0 Flagellar protein FliT Scs3p PF10261.4 EMC88866.1 - 6.9e-35 120.2 17.1 1.3e-34 119.3 11.8 1.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 EMC88866.1 - 0.00017 21.2 5.1 0.00017 21.2 3.5 1.9 1 1 1 2 2 2 1 PAP2 superfamily ARL6IP6 PF15062.1 EMC88866.1 - 0.036 13.9 0.6 0.036 13.9 0.4 1.9 2 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix DHDPS PF00701.17 EMC88866.1 - 0.17 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family CAP PF00188.21 EMC88867.1 - 1.5e-20 73.9 4.5 2e-20 73.5 3.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CRAL_TRIO PF00650.15 EMC88868.1 - 4.6e-34 117.2 0.0 6.4e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC88868.1 - 2.8e-11 43.3 0.2 8.7e-11 41.7 0.3 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMC88868.1 - 5.5e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Serinc PF03348.10 EMC88869.1 - 6.8e-180 598.3 19.8 7.7e-180 598.1 13.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) PKI PF02827.11 EMC88870.1 - 9e-16 57.7 0.0 9.3e-16 57.7 0.0 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor A_deaminase PF00962.17 EMC88871.1 - 1.3e-89 300.4 0.0 1.4e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase IGFBP PF00219.13 EMC88872.1 - 3.5e-14 53.0 22.0 3.5e-14 53.0 15.3 2.6 2 1 0 2 2 2 1 Insulin-like growth factor binding protein VWC PF00093.13 EMC88872.1 - 1.7e-05 24.7 2.6 1.7e-05 24.7 1.8 3.1 3 1 0 3 3 3 1 von Willebrand factor type C domain PMR5N PF14416.1 EMC88872.1 - 0.066 13.2 0.9 0.066 13.2 0.6 2.7 2 1 1 3 3 3 0 PMR5 N terminal Domain 7tm_1 PF00001.16 EMC88873.1 - 1.3e-43 149.0 3.3 1.6e-43 148.7 2.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cad PF03596.8 EMC88873.1 - 0.038 13.7 1.3 0.085 12.5 0.9 1.5 1 0 0 1 1 1 0 Cadmium resistance transporter DUF2975 PF11188.3 EMC88873.1 - 0.065 12.9 0.7 0.14 11.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) YfhO PF09586.5 EMC88873.1 - 0.18 9.7 1.9 0.26 9.2 1.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ion_trans_2 PF07885.11 EMC88874.1 - 3.3e-36 122.8 16.0 8.6e-20 70.2 0.6 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 EMC88874.1 - 0.0012 18.1 15.4 0.045 12.9 0.8 2.6 1 1 1 2 2 2 2 Ion transport protein IRK PF01007.15 EMC88874.1 - 0.39 9.4 3.9 0.28 9.9 0.1 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel DUF981 PF06168.6 EMC88874.1 - 0.93 9.2 8.5 0.12 12.1 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF981) zf-DHHC PF01529.15 EMC88874.1 - 3.2 7.1 6.8 0.52 9.6 1.6 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2101 PF09874.4 EMC88874.1 - 7.5 5.9 10.3 15 4.9 0.2 2.6 1 1 0 2 2 2 0 Predicted membrane protein (DUF2101) C2 PF00168.25 EMC88875.1 - 4.9e-13 48.7 0.0 7.2e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain 14-3-3 PF00244.15 EMC88876.1 - 1.5e-112 374.4 11.9 1.7e-112 374.2 8.3 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.10 EMC88876.1 - 0.042 13.5 0.2 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF4303 PF14136.1 EMC88876.1 - 0.11 12.1 2.6 2.6 7.6 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) DUF3802 PF12290.3 EMC88876.1 - 0.22 11.8 2.3 39 4.6 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3802) CCDC-167 PF15188.1 EMC88876.1 - 0.85 9.6 5.8 0.52 10.3 0.4 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Drf_FH3 PF06367.11 EMC88876.1 - 1.6 8.0 5.6 0.26 10.6 0.8 2.0 3 0 0 3 3 3 0 Diaphanous FH3 Domain RRM_1 PF00076.17 EMC88877.1 - 5.3e-86 282.2 1.5 1.2e-20 72.8 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC88877.1 - 7.7e-56 185.9 3.5 2.7e-12 46.4 0.0 4.9 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC88877.1 - 9.6e-42 140.6 0.1 1.3e-10 40.9 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EMC88877.1 - 1.1e-31 108.3 0.2 2.5e-31 107.1 0.1 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EMC88877.1 - 3.1e-05 23.6 0.1 1.2 8.9 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EMC88877.1 - 0.041 14.1 0.0 15 5.9 0.0 3.7 4 0 0 4 4 4 0 Cobalamin biosynthesis central region OB_RNB PF08206.6 EMC88877.1 - 0.077 12.5 5.5 14 5.2 0.1 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain TPR_11 PF13414.1 EMC88878.1 - 2.2e-29 100.8 15.5 3.2e-15 55.5 1.3 3.2 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EMC88878.1 - 1.6e-25 87.5 12.2 2.7e-10 39.3 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMC88878.1 - 6.1e-21 72.6 9.6 5e-07 29.1 0.1 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC88878.1 - 1.6e-12 47.7 0.0 5.8e-07 30.0 0.0 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC88878.1 - 8.5e-12 43.9 12.9 4.1e-05 23.0 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC88878.1 - 3.1e-10 39.7 5.6 0.0017 18.7 0.1 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMC88878.1 - 3.9e-09 36.3 8.7 3.4e-05 23.7 0.7 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC88878.1 - 2.2e-07 30.5 6.6 0.00032 20.6 0.1 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC88878.1 - 9.7e-07 28.5 3.0 0.00077 19.2 0.2 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMC88878.1 - 1.3e-06 28.6 8.9 3.3e-05 24.1 3.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EMC88878.1 - 2.7e-06 27.4 4.9 2.7e-06 27.4 3.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EMC88878.1 - 3.5e-05 23.6 9.7 0.0035 17.1 0.5 3.5 4 1 1 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EMC88878.1 - 4.5e-05 22.9 5.4 0.61 10.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EMC88878.1 - 0.018 15.3 0.5 0.018 15.3 0.4 2.0 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_15 PF13429.1 EMC88878.1 - 0.023 13.7 5.6 0.026 13.5 0.4 2.9 2 1 2 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMC88878.1 - 0.076 12.2 6.8 2.5 7.4 0.0 4.3 5 0 0 5 5 5 0 SHNi-TPR GNT-I PF03071.10 EMC88878.1 - 0.088 11.3 0.2 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 GNT-I family MIT PF04212.13 EMC88878.1 - 0.11 12.3 11.9 8.5 6.3 0.3 3.7 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EMC88878.1 - 0.12 12.8 12.8 0.43 11.1 0.4 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 EMC88879.1 - 9.1e-69 231.4 0.0 1.4e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88879.1 - 1.5e-51 174.9 0.0 2.2e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC88879.1 - 0.0024 16.9 0.1 0.37 9.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Cortexin PF11057.3 EMC88880.1 - 9e-40 134.1 0.1 9.2e-40 134.1 0.1 1.0 1 0 0 1 1 1 1 Cortexin of kidney Ca_hom_mod PF14798.1 EMC88880.1 - 0.018 13.9 0.0 0.019 13.9 0.0 1.0 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF3317 PF11779.3 EMC88880.1 - 0.077 12.4 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF2701 PF10857.3 EMC88880.1 - 0.15 11.8 2.9 0.19 11.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) Tim44 PF04280.10 EMC88881.1 - 8.6e-40 136.0 0.3 3.8e-39 133.9 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain HalX PF08663.5 EMC88881.1 - 0.06 13.3 2.5 0.32 11.0 0.0 2.9 1 1 2 3 3 3 0 HalX domain Prominin PF05478.6 EMC88881.1 - 0.067 10.7 0.4 0.1 10.1 0.3 1.2 1 0 0 1 1 1 0 Prominin ISG65-75 PF11727.3 EMC88881.1 - 2.6 7.0 11.4 5.2 6.0 7.9 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein RRM_1 PF00076.17 EMC88882.1 - 7.3e-23 79.9 0.1 1e-10 41.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC88882.1 - 8.9e-14 51.2 0.3 3.9e-06 26.7 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC88882.1 - 8.5e-06 25.5 0.1 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF572 PF04502.8 EMC88883.1 - 1.4e-94 316.9 22.0 1.6e-94 316.8 15.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EMC88883.1 - 0.093 12.5 0.3 2.1 8.2 0.0 2.1 1 1 0 2 2 2 0 Benyvirus 14KDa protein DUF1436 PF07262.6 EMC88883.1 - 0.2 11.1 2.9 0.42 10.0 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) SH2 PF00017.19 EMC88884.1 - 1.9e-15 56.4 0.0 2.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain SPRY PF00622.23 EMC88885.1 - 9.4e-14 51.5 0.1 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.16 EMC88885.1 - 8.4e-08 32.2 0.0 4.6e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain CENP-K PF11802.3 EMC88885.1 - 0.059 12.5 2.9 0.082 12.1 2.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K AAA_13 PF13166.1 EMC88885.1 - 0.14 10.5 3.8 0.18 10.2 2.6 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 EMC88885.1 - 0.21 10.7 4.3 0.3 10.2 3.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit JAB PF01398.16 EMC88886.1 - 6.3e-10 38.8 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMC88886.1 - 1.6e-06 27.6 0.1 2.3e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain BAR PF03114.13 EMC88887.1 - 1.1e-40 139.5 8.3 1.3e-40 139.3 5.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EMC88887.1 - 2.3e-15 55.8 0.1 3.9e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC88887.1 - 3e-15 55.3 0.1 6.4e-15 54.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC88887.1 - 2.9e-13 49.1 0.0 5.4e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 EMC88887.1 - 1.9e-08 33.5 6.9 2.6e-08 33.1 4.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Exonuc_VII_L PF02601.10 EMC88887.1 - 0.012 14.8 2.7 0.014 14.6 1.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MscS_porin PF12795.2 EMC88887.1 - 0.11 11.8 5.5 0.14 11.4 3.6 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF29 PF01724.11 EMC88887.1 - 0.25 11.1 3.6 0.44 10.3 2.1 1.6 1 1 1 2 2 2 0 Domain of unknown function DUF29 Perilipin PF03036.11 EMC88888.1 - 1e-141 472.3 13.6 1.1e-141 472.1 9.4 1.0 1 0 0 1 1 1 1 Perilipin family Prefoldin_3 PF13758.1 EMC88888.1 - 0.054 13.2 0.2 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 Prefoldin subunit SF-assemblin PF06705.6 EMC88888.1 - 0.072 12.2 0.3 0.29 10.2 0.0 2.0 2 1 0 2 2 2 0 SF-assemblin/beta giardin FANCI_S4 PF14678.1 EMC88888.1 - 0.11 11.6 0.4 0.45 9.5 0.0 2.0 1 1 1 2 2 2 0 FANCI solenoid 4 COG2 PF06148.6 EMC88888.1 - 0.19 11.6 2.0 3 7.7 1.3 3.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin PF00804.20 EMC88888.1 - 0.32 11.1 3.4 0.85 9.8 0.6 2.8 2 1 1 3 3 3 0 Syntaxin Carbpep_Y_N PF05388.6 EMC88888.1 - 0.41 10.8 2.0 0.94 9.6 0.1 2.5 3 1 0 3 3 3 0 Carboxypeptidase Y pro-peptide DUF2580 PF10824.3 EMC88888.1 - 0.61 10.4 6.8 0.35 11.2 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2580) PilJ PF13675.1 EMC88888.1 - 0.73 10.1 8.0 3.3 8.0 0.4 3.1 2 2 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EMC88888.1 - 2.3 8.0 6.7 15 5.4 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 EMC88888.1 - 3.1 7.3 10.8 10 5.6 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 YlbD_coat PF14071.1 EMC88888.1 - 3.4 7.7 5.8 1.6 8.8 0.3 2.9 1 1 1 2 2 2 0 Putative coat protein LRR_8 PF13855.1 EMC88889.1 - 4.5e-37 125.6 7.1 9.5e-19 66.9 0.3 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC88889.1 - 2.1e-24 84.6 13.2 1.1e-06 28.1 0.1 4.9 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC88889.1 - 2.3e-22 75.5 11.2 0.039 13.9 0.0 8.0 8 0 0 8 8 8 7 Leucine Rich Repeat LRR_7 PF13504.1 EMC88889.1 - 1e-13 49.0 25.9 0.045 13.9 0.1 8.3 8 1 0 8 8 8 6 Leucine rich repeat LRR_6 PF13516.1 EMC88889.1 - 5.5e-09 35.1 15.0 1.6 8.9 0.0 7.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_9 PF14580.1 EMC88889.1 - 8e-05 22.2 1.9 0.014 14.9 0.2 2.4 1 1 2 3 3 3 3 Leucine-rich repeat DUF758 PF05527.6 EMC88891.1 - 6.5e-98 325.8 3.9 7.2e-98 325.6 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF3877 PF12993.2 EMC88891.1 - 0.0045 16.5 0.5 0.0085 15.6 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3387 PF11867.3 EMC88891.1 - 0.033 13.1 2.0 0.05 12.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Pilus_CpaD PF09476.5 EMC88891.1 - 0.086 12.3 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pico_P2B PF01552.12 EMC88891.1 - 0.1 12.7 0.1 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Picornavirus 2B protein UPF0556 PF10572.4 EMC88892.1 - 5e-65 217.4 0.2 5.5e-65 217.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 Peptidase_C1 PF00112.18 EMC88893.1 - 2.8e-60 203.9 0.1 3.6e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EMC88893.1 - 1.1e-15 57.6 0.5 1.8e-15 56.9 0.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EMC88893.1 - 0.00019 20.1 0.2 0.13 10.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DPPIV_N PF00930.16 EMC88894.1 - 9.5e-102 340.1 0.0 1.2e-101 339.7 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMC88894.1 - 1.2e-53 181.5 0.0 2.2e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMC88894.1 - 7.2e-07 28.9 0.1 1.5e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EMC88894.1 - 2.1e-05 24.2 0.0 7.3e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMC88894.1 - 0.00011 22.1 0.0 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EMC88894.1 - 0.01 15.3 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EMC88894.1 - 0.024 14.0 0.1 7.3 5.9 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EMC88894.1 - 0.03 13.5 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF4439 PF14530.1 EMC88894.1 - 0.075 13.5 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) TIR_2 PF13676.1 EMC88895.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 TIR domain Perilipin PF03036.11 EMC88896.1 - 3.1e-119 398.3 18.8 5e-118 394.3 13.0 1.9 1 1 0 1 1 1 1 Perilipin family Cdd1 PF11731.3 EMC88896.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus DUF948 PF06103.6 EMC88896.1 - 0.65 9.9 8.0 7.4 6.5 0.0 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-HC5HC2H_2 PF13832.1 EMC88897.1 - 8.4e-37 125.5 7.3 8.4e-37 125.5 5.1 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain JmjC PF02373.17 EMC88897.1 - 6.6e-34 116.5 1.0 6.7e-33 113.3 0.7 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 EMC88897.1 - 2.3e-18 66.1 3.8 2.3e-18 66.1 2.6 2.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 EMC88897.1 - 1.3e-13 50.2 0.0 3.3e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 EMC88897.1 - 2.2e-13 49.2 6.6 2.2e-13 49.2 4.6 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EMC88897.1 - 3.4e-06 26.6 20.8 4e-05 23.2 1.7 3.4 3 0 0 3 3 3 2 PHD-finger LBR_tudor PF09465.5 EMC88897.1 - 0.0024 17.4 0.8 0.37 10.4 0.0 2.7 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.1 EMC88897.1 - 0.021 14.5 0.1 0.091 12.5 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) zf-RING_2 PF13639.1 EMC88898.1 - 2.9e-14 52.5 8.7 8.5e-14 51.1 6.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMC88898.1 - 1.5e-10 41.0 3.0 3.4e-10 39.8 2.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC88898.1 - 1e-07 31.5 8.4 2.4e-07 30.3 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMC88898.1 - 1.1e-07 31.7 9.4 3.1e-07 30.2 6.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC88898.1 - 4.7e-07 29.3 9.6 1.3e-06 27.9 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC88898.1 - 2.7e-06 26.9 6.6 6.1e-06 25.8 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.17 EMC88898.1 - 0.00015 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-Apc11 PF12861.2 EMC88898.1 - 0.00024 20.8 4.0 0.00049 19.8 2.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMC88898.1 - 0.26 11.3 8.1 0.75 9.8 5.6 1.8 1 0 0 1 1 1 0 RING-variant domain GAGA PF09237.6 EMC88898.1 - 0.26 10.9 2.5 16 5.1 1.1 2.6 2 0 0 2 2 2 0 GAGA factor FANCL_C PF11793.3 EMC88898.1 - 0.29 11.1 8.4 1.5 8.8 5.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EMC88898.1 - 0.91 9.2 8.9 0.19 11.4 0.9 2.6 2 0 0 2 2 2 0 RING-type zinc-finger PHD PF00628.24 EMC88898.1 - 3.5 7.3 11.7 0.81 9.4 5.6 1.9 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.1 EMC88899.1 - 1.1e-10 41.1 8.3 1.1e-10 41.1 5.7 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EMC88899.1 - 8.2e-06 25.4 6.6 8.2e-06 25.4 4.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC88899.1 - 2.9e-05 24.0 6.1 2.9e-05 24.0 4.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMC88899.1 - 7.5e-05 22.2 11.3 0.0001 21.9 5.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC88899.1 - 0.00032 20.2 5.5 0.00032 20.2 3.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC88899.1 - 0.0009 19.2 8.6 0.0009 19.2 6.0 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMC88899.1 - 0.0034 17.1 5.8 0.0065 16.2 3.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EMC88899.1 - 4 7.2 10.1 1 9.0 4.5 2.0 2 0 0 2 2 2 0 PHD-finger Tropomyosin PF00261.15 EMC88900.1 - 7.1e-105 349.3 85.9 3.1e-99 330.8 43.0 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 EMC88900.1 - 6.3e-40 136.3 73.4 7.6e-36 123.0 27.8 3.1 2 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.7 EMC88900.1 - 1.6e-07 31.1 31.8 0.00042 20.0 4.5 3.3 1 1 2 3 3 3 2 Laminin Domain II MscS_porin PF12795.2 EMC88900.1 - 5.1e-05 22.6 37.9 0.017 14.4 12.1 2.6 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain Laminin_I PF06008.9 EMC88900.1 - 0.00025 20.4 49.1 0.0013 18.0 9.3 3.0 1 1 2 3 3 3 2 Laminin Domain I TMF_DNA_bd PF12329.3 EMC88900.1 - 0.00059 19.5 14.9 0.00059 19.5 10.3 6.2 1 1 3 5 5 4 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EMC88900.1 - 0.00097 18.7 56.5 0.0018 17.9 14.7 3.0 1 1 2 3 3 3 1 IncA protein Reo_sigmaC PF04582.7 EMC88900.1 - 0.0015 17.7 7.1 0.025 13.7 0.6 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EMC88900.1 - 0.0038 17.0 65.9 0.021 14.6 21.7 2.5 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EMC88900.1 - 0.0053 15.2 49.8 0.045 12.2 20.3 2.0 1 1 1 2 2 2 2 AAA domain ATG16 PF08614.6 EMC88900.1 - 0.012 15.4 9.9 0.012 15.4 6.8 3.7 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) WEMBL PF05701.6 EMC88900.1 - 0.017 13.5 70.3 0.0071 14.8 12.6 3.8 1 1 3 4 4 4 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 EMC88900.1 - 0.069 10.8 68.5 0.0092 13.7 40.1 2.2 1 1 0 1 1 1 0 Myosin tail Flagellin_N PF00669.15 EMC88900.1 - 0.082 12.6 14.5 0.38 10.5 2.6 3.6 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region RmuC PF02646.11 EMC88900.1 - 0.12 11.1 28.7 0.08 11.7 1.4 3.9 1 1 3 4 4 4 0 RmuC family DUF4200 PF13863.1 EMC88900.1 - 0.13 12.1 67.7 0.28 11.1 17.8 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 EMC88900.1 - 0.39 10.9 19.0 3.4 7.9 1.6 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EMC88900.1 - 0.4 10.8 32.1 1 9.4 4.8 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EMC88900.1 - 0.5 10.7 37.6 0.15 12.4 0.6 5.8 2 2 2 5 5 5 0 SlyX DUF869 PF05911.6 EMC88900.1 - 0.6 8.2 52.8 4.9 5.2 16.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) EzrA PF06160.7 EMC88900.1 - 0.6 8.2 49.9 15 3.5 21.8 3.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA APG6 PF04111.7 EMC88900.1 - 1.5 7.7 60.4 0.53 9.2 15.8 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 ADIP PF11559.3 EMC88900.1 - 1.9 8.4 49.7 1.1 9.1 4.6 4.0 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Nup54 PF13874.1 EMC88900.1 - 2.4 7.8 34.2 2.6 7.7 1.3 4.1 1 1 4 5 5 5 0 Nucleoporin complex subunit 54 FH2 PF02181.18 EMC88900.1 - 2.7 6.7 38.7 0.22 10.3 6.1 3.2 1 1 2 3 3 3 0 Formin Homology 2 Domain DUF3584 PF12128.3 EMC88900.1 - 4.3 4.5 54.9 1.1 6.4 16.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GTPase_Cys_C PF12631.2 EMC88900.1 - 4.8 7.6 20.7 0.21 11.9 3.1 4.5 1 1 3 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE GAS PF13851.1 EMC88900.1 - 5.6 6.1 61.8 6 6.0 11.6 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Flagellin_C PF00700.16 EMC88900.1 - 6.6 6.9 15.0 3.6 7.8 0.2 4.4 2 2 2 4 4 4 0 Bacterial flagellin C-terminal helical region TMCO5 PF14992.1 EMC88900.1 - 7.1 5.6 51.5 0.53 9.3 7.1 2.9 1 1 2 3 3 3 0 TMCO5 family MAD PF05557.8 EMC88900.1 - 7.8 4.4 58.7 20 3.1 33.6 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein LOH1CR12 PF10158.4 EMC88900.1 - 9.2 6.0 15.7 1 9.1 1.3 3.5 2 2 2 4 4 4 0 Tumour suppressor protein Uds1 PF15456.1 EMC88900.1 - 9.9 6.1 49.2 58 3.7 7.6 5.4 1 1 4 5 5 5 0 Up-regulated During Septation Ras PF00071.17 EMC88901.1 - 5.7e-51 172.1 0.2 6.7e-51 171.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC88901.1 - 3.6e-11 43.6 0.0 6.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC88901.1 - 2.6e-10 39.8 0.2 3e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC88901.1 - 0.00058 19.3 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC88901.1 - 0.0026 16.9 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3963 PF13124.1 EMC88901.1 - 0.056 13.2 0.4 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) DGF-1_5 PF11038.3 EMC88902.1 - 0.43 9.7 5.4 1.4 8.0 1.2 2.4 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Crisp PF08562.5 EMC88902.1 - 2.9 8.2 10.0 5.6 7.3 0.4 2.8 1 1 2 3 3 3 0 Crisp Metallothio_Euk PF12749.2 EMC88902.1 - 7.7 6.6 14.6 1.3 9.1 5.3 2.1 1 1 1 2 2 2 0 Eukaryotic metallothionein Phage_NinH PF06322.6 EMC88902.1 - 10 5.8 9.9 44 3.7 0.1 3.9 1 1 3 4 4 4 0 Phage NinH protein DOT1 PF08123.8 EMC88903.1 - 1.9e-83 278.7 0.4 6.9e-83 276.9 0.0 2.0 2 0 0 2 2 2 1 Histone methylation protein DOT1 PH PF00169.24 EMC88904.1 - 7.3e-09 35.7 0.1 1.2e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC88904.1 - 0.00038 20.6 0.1 0.0016 18.6 0.0 1.9 1 1 1 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EMC88904.1 - 0.0025 17.6 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EMC88904.1 - 0.011 15.7 0.0 0.085 12.9 0.0 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.1 EMC88904.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-met PF12874.2 EMC88905.1 - 1.3e-06 28.4 2.0 1.3e-06 28.4 1.4 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EMC88905.1 - 0.0091 15.5 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EMC88905.1 - 0.052 12.8 2.5 0.09 12.0 1.7 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like AMH_N PF04709.7 EMC88906.1 - 1.1e-115 386.5 10.3 1.5e-115 386.1 7.1 1.1 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.15 EMC88906.1 - 5.1e-20 71.7 0.2 8.3e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain JSRP PF15312.1 EMC88907.1 - 8.6e-18 64.0 2.3 8.6e-18 64.0 1.6 2.7 3 0 0 3 3 3 1 Junctional sarcoplasmic reticulum protein DUF4593 PF15263.1 EMC88907.1 - 0.028 14.3 0.3 0.028 14.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4593) Sigma70_ner PF04546.8 EMC88907.1 - 1.4 8.4 12.0 2.2 7.8 8.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.20 EMC88908.1 - 0.077 12.1 0.0 0.19 10.8 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain LRR_8 PF13855.1 EMC88909.1 - 3.4e-41 138.7 37.1 7.4e-13 48.0 2.5 5.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EMC88909.1 - 1.4e-22 78.8 31.9 2.8e-07 29.9 0.2 6.6 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC88909.1 - 7.4e-18 64.4 0.1 2e-11 43.6 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) I-set PF07679.11 EMC88909.1 - 1.5e-16 59.9 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 EMC88909.1 - 6.9e-13 46.7 31.7 0.02 14.8 0.0 10.7 11 0 0 11 11 11 3 Leucine Rich Repeat Ig_2 PF13895.1 EMC88909.1 - 7.4e-08 32.4 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 EMC88909.1 - 2.3e-07 30.1 20.8 2.1 8.6 0.0 8.9 7 1 1 8 8 8 1 Leucine Rich repeat Ig_3 PF13927.1 EMC88909.1 - 6.5e-07 29.7 0.0 3.8e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC88909.1 - 7.7e-07 29.0 0.0 5.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 EMC88909.1 - 2.3e-05 24.4 0.0 5.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRRCT PF01463.19 EMC88909.1 - 0.001 19.1 1.9 0.68 10.4 0.1 4.0 3 1 0 3 3 3 1 Leucine rich repeat C-terminal domain LRRNT PF01462.13 EMC88909.1 - 0.0075 15.7 3.4 0.0075 15.7 2.3 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EMC88909.1 - 0.012 15.6 28.1 7.6 7.2 0.1 9.6 10 0 0 10 10 10 0 Leucine rich repeat p450 PF00067.17 EMC88911.1 - 1.7e-50 171.9 5.0 3.9e-27 94.8 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 Hormone_recep PF00104.25 EMC88912.1 - 4.1e-30 104.4 0.2 1.9e-29 102.2 0.2 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PRT_C PF08372.5 EMC88913.1 - 1.8e-08 34.0 0.1 2.2e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal MHC2-interact PF09307.5 EMC88913.1 - 0.052 13.3 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting DUF1426 PF07234.6 EMC88913.1 - 0.23 11.2 1.5 0.31 10.7 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1426) Lectin_C PF00059.16 EMC88914.1 - 4.2e-18 65.9 2.2 4.7e-18 65.7 0.6 1.8 2 0 0 2 2 2 1 Lectin C-type domain Ldl_recept_a PF00057.13 EMC88914.1 - 8.3e-11 41.6 7.5 8.3e-11 41.6 5.2 3.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A Herpes_UL45 PF05473.7 EMC88914.1 - 0.001 18.5 0.4 0.0023 17.3 0.0 1.7 2 0 0 2 2 2 1 UL45 protein Pkinase PF00069.20 EMC88915.1 - 8.3e-66 221.7 0.1 9.4e-66 221.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88915.1 - 2.7e-37 128.2 0.0 3.3e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC88915.1 - 3.4e-05 22.9 0.0 5.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC88915.1 - 4.8e-05 22.4 0.0 8.2e-05 21.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EMC88915.1 - 0.0022 17.5 0.4 0.0042 16.6 0.2 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMC88915.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Homeobox PF00046.24 EMC88916.1 - 1.5e-22 78.9 4.6 2.5e-22 78.2 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC88916.1 - 0.027 14.1 0.1 0.078 12.6 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain TSP_1 PF00090.14 EMC88917.1 - 1.7e-09 37.6 6.2 1.7e-09 37.6 4.3 2.4 3 0 0 3 3 3 1 Thrombospondin type 1 domain Somatomedin_B PF01033.12 EMC88917.1 - 5.2e-06 26.3 20.5 5.2e-06 26.3 14.2 3.1 3 0 0 3 3 3 1 Somatomedin B domain Mito_carr PF00153.22 EMC88918.1 - 3.5e-68 225.3 0.2 1.5e-22 79.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3748 PF12566.3 EMC88918.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) PI3_PI4_kinase PF00454.22 EMC88919.1 - 1.3e-39 136.0 0.2 1.3e-38 132.8 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EMC88919.1 - 3e-33 114.5 0.0 7.2e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 EMC88919.1 - 0.0073 16.2 0.5 0.37 10.7 0.1 3.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation BTB PF00651.26 EMC88921.1 - 7.2e-27 93.5 0.2 1.1e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 EMC88921.1 - 2.8e-25 87.0 24.7 8.9e-06 25.7 0.8 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC88921.1 - 5e-22 76.5 21.0 1.7e-05 24.7 0.2 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC88921.1 - 1.9e-21 75.2 29.5 2.5e-08 33.7 0.2 7.5 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC88921.1 - 3.9e-18 65.0 4.5 0.00032 20.7 0.2 5.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC88921.1 - 6.3e-12 45.2 14.1 0.0028 17.7 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC88921.1 - 5.3e-10 38.8 12.1 0.06 13.2 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.7 EMC88921.1 - 0.00087 19.3 11.5 0.14 12.3 0.4 3.7 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMC88921.1 - 0.0018 18.3 14.8 5.6 7.1 0.1 5.1 1 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.14 EMC88921.1 - 0.013 15.5 6.0 7.3 6.7 0.0 3.8 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.10 EMC88921.1 - 0.065 13.0 18.5 1.8 8.4 3.4 5.6 4 1 1 5 5 5 0 BED zinc finger LIM PF00412.17 EMC88921.1 - 0.1 12.6 0.4 0.1 12.6 0.3 3.5 3 1 1 4 4 2 0 LIM domain GAGA PF09237.6 EMC88921.1 - 0.11 12.0 4.1 1.3 8.6 0.1 3.1 2 1 1 3 3 3 0 GAGA factor C1_1 PF00130.17 EMC88921.1 - 0.15 11.7 7.4 0.42 10.3 0.8 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 EMC88921.1 - 0.62 10.2 9.1 8.5 6.6 4.7 3.0 2 1 0 2 2 1 0 CHY zinc finger zf-HYPF PF07503.7 EMC88921.1 - 0.65 9.4 8.0 4.4 6.8 0.6 3.3 3 1 0 3 3 3 0 HypF finger zf-AN1 PF01428.11 EMC88921.1 - 1.9 8.3 10.6 42 4.1 0.2 4.5 4 0 0 4 4 4 0 AN1-like Zinc finger zf-RING_5 PF14634.1 EMC88921.1 - 4.3 7.1 7.6 84 3.0 0.1 3.6 2 1 0 2 2 2 0 zinc-RING finger domain UQ_con PF00179.21 EMC88923.1 - 6.5e-43 145.5 0.3 7.2e-43 145.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC88923.1 - 2e-07 30.8 0.0 2.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EMC88923.1 - 5.1e-05 22.9 0.1 8.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EMC88923.1 - 0.00016 21.5 0.8 0.0002 21.2 0.5 1.6 1 1 0 1 1 1 1 RWD domain YdjC PF04794.7 EMC88924.1 - 1e-36 126.7 0.0 1.1e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein MIR PF02815.14 EMC88925.1 - 7.6e-15 54.9 0.1 5.2e-12 45.6 0.0 2.3 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 EMC88925.1 - 0.064 12.2 0.0 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.1 EMC88925.1 - 0.087 13.1 0.2 0.96 9.8 0.1 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Topoisom_bac PF01131.15 EMC88926.1 - 1.7e-105 353.1 0.0 2.1e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EMC88926.1 - 1.3e-18 66.7 0.0 2.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF3628 PF12300.3 EMC88926.1 - 0.049 13.6 1.3 0.09 12.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Fer4_11 PF13247.1 EMC88926.1 - 1.5 8.7 11.4 0.15 11.9 4.4 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain PP2C PF00481.16 EMC88927.1 - 4.7e-65 219.5 0.0 5.8e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMC88927.1 - 0.00084 18.8 0.2 0.0047 16.3 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C HHH_5 PF14520.1 EMC88927.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Pkinase PF00069.20 EMC88929.1 - 2.8e-66 223.3 0.2 3.2e-66 223.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88929.1 - 5.3e-32 110.9 0.0 7.7e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC88929.1 - 0.00021 21.1 0.1 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YukC PF10140.4 EMC88929.1 - 0.011 14.3 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 EMC88929.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EMC88929.1 - 0.1 11.6 0.4 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMC88929.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Yippee-Mis18 PF03226.9 EMC88930.1 - 4.1e-18 65.2 0.3 5.4e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 EMC88930.1 - 0.008 16.3 5.3 0.023 14.8 3.7 1.8 1 1 0 1 1 1 1 CHY zinc finger RIG-I_C-RD PF11648.3 EMC88930.1 - 0.11 12.4 0.4 0.21 11.4 0.3 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 EMC88930.1 - 0.29 11.0 3.8 0.48 10.3 0.5 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Pro_isomerase PF00160.16 EMC88931.1 - 8.9e-50 168.9 0.1 2e-49 167.7 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EMC88931.1 - 1.8e-06 27.3 0.1 1.8e-06 27.3 0.1 2.5 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EMC88931.1 - 0.0012 18.8 0.0 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 1 U-box domain Hira PF07569.6 EMC88932.1 - 2.3e-57 193.6 0.1 5.6e-57 192.4 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EMC88932.1 - 2.5e-40 134.9 25.4 3.1e-09 36.3 3.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat HIRA_B PF09453.5 EMC88932.1 - 1.1e-08 34.3 0.1 2.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 HIRA B motif MRP-L28 PF09812.4 EMC88933.1 - 4.2e-52 176.1 8.7 4.6e-52 175.9 6.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PsiA PF06952.6 EMC88933.1 - 0.033 13.2 3.2 0.041 12.9 2.2 1.1 1 0 0 1 1 1 0 PsiA protein Histone_HNS PF00816.16 EMC88933.1 - 0.2 12.1 6.5 2.9 8.4 0.4 2.2 2 0 0 2 2 2 0 H-NS histone family DUF4207 PF13904.1 EMC88933.1 - 0.78 9.0 13.3 1.3 8.3 9.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) DUF3128 PF11326.3 EMC88934.1 - 0.009 16.1 2.5 0.011 15.8 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) UFD1 PF03152.9 EMC88935.1 - 2.8e-81 270.8 0.0 3.4e-81 270.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EMC88935.1 - 0.018 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 CDC45 PF02724.9 EMC88936.1 - 1.6e-181 604.5 17.8 5.7e-180 599.4 12.3 2.6 1 1 0 1 1 1 1 CDC45-like protein CLAMP PF14769.1 EMC88936.1 - 0.025 14.7 0.3 0.24 11.5 0.0 2.6 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Septin PF00735.13 EMC88937.1 - 1.3e-122 408.2 0.1 1.6e-122 407.9 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMC88937.1 - 1.9e-07 30.9 0.0 4.1e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC88937.1 - 1.2e-05 24.8 0.0 0.0012 18.3 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EMC88937.1 - 3.7e-05 22.9 0.9 0.0001 21.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EMC88937.1 - 4.5e-05 23.3 1.6 0.047 13.5 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 EMC88937.1 - 7e-05 22.2 0.0 0.00024 20.5 0.0 1.9 1 1 0 1 1 1 1 Ras family DUF258 PF03193.11 EMC88937.1 - 0.0001 21.5 0.1 0.00025 20.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMC88937.1 - 0.0004 20.5 0.1 0.002 18.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EMC88937.1 - 0.0027 17.2 0.1 0.0031 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 EMC88937.1 - 0.0066 15.6 0.0 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EMC88937.1 - 0.011 15.9 1.4 0.024 14.9 0.2 2.1 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 EMC88937.1 - 0.016 15.6 0.9 0.045 14.2 0.0 2.2 3 0 0 3 3 2 0 Miro-like protein AAA_29 PF13555.1 EMC88937.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMC88937.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EMC88937.1 - 0.043 14.1 0.5 0.16 12.2 0.4 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EMC88937.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF977 PF06163.6 EMC88937.1 - 0.091 12.5 0.7 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Glyco_transf_6 PF03414.8 EMC88937.1 - 0.17 10.3 0.1 0.17 10.3 0.1 1.7 2 0 0 2 2 2 0 Glycosyltransferase family 6 FtsK_SpoIIIE PF01580.13 EMC88937.1 - 0.27 10.6 2.3 0.47 9.9 0.0 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family Cpn60_TCP1 PF00118.19 EMC88938.1 - 1.2e-137 459.4 9.6 1.5e-137 459.1 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_4 PF12799.2 EMC88939.1 - 1.2e-23 82.2 21.5 3.2e-06 26.6 4.2 5.6 2 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC88939.1 - 3.4e-13 49.1 18.8 0.00014 21.5 2.9 4.0 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EMC88939.1 - 4.2e-11 41.2 28.7 0.045 13.7 0.6 8.3 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC88939.1 - 0.0003 20.4 24.6 5.7 7.6 0.4 8.1 8 0 0 8 8 8 3 Leucine rich repeat Rota_NS6 PF04866.7 EMC88939.1 - 2 8.4 7.1 0.94 9.5 1.3 2.8 3 1 1 4 4 4 0 Rotavirus non-structural protein 6 Asp PF00026.18 EMC88940.1 - 1.7e-115 385.6 0.2 2e-115 385.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC88940.1 - 2.9e-07 30.5 0.0 5.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 EMC88940.1 - 4.2e-06 26.3 1.0 7.5e-06 25.5 0.7 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.1 EMC88940.1 - 2.8e-05 23.7 0.0 6.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Bestrophin PF01062.16 EMC88941.1 - 3.6e-96 321.5 6.5 4.5e-96 321.2 4.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sec2p PF06428.6 EMC88942.1 - 1.4e-25 89.0 9.2 2.7e-25 88.1 6.2 1.6 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 EMC88942.1 - 0.00091 17.0 10.6 0.0013 16.6 7.4 1.1 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 EMC88942.1 - 0.014 13.9 4.8 0.019 13.4 3.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EMC88942.1 - 0.1 9.9 7.5 0.14 9.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EMC88942.1 - 0.5 9.3 9.1 0.76 8.7 6.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 EMC88942.1 - 0.9 9.4 14.8 2.2 8.2 10.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 EMC88942.1 - 0.93 9.5 10.0 1.9 8.5 6.9 1.5 1 0 0 1 1 1 0 DivIVA protein Tropomyosin_1 PF12718.2 EMC88942.1 - 1.4 8.7 16.0 4.2 7.2 11.1 1.7 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 EMC88942.1 - 6.1 6.4 13.0 16 4.9 9.0 1.6 1 1 0 1 1 1 0 IncA protein NOT2_3_5 PF04153.13 EMC88943.1 - 5.4e-34 116.9 0.2 1e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family SBDS_C PF09377.5 EMC88944.1 - 6.5e-43 145.4 0.9 9.6e-43 144.8 0.6 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EMC88944.1 - 7.8e-21 73.6 0.7 1.6e-20 72.7 0.5 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.14 EMC88944.1 - 0.055 12.6 0.1 0.17 11.0 0.0 1.8 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dehydratase_SU PF02287.10 EMC88944.1 - 0.069 12.8 0.5 0.093 12.4 0.3 1.3 1 0 0 1 1 1 0 Dehydratase small subunit Radical_SAM PF04055.16 EMC88945.1 - 3.8e-33 114.9 0.0 8.2e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EMC88945.1 - 4e-25 87.6 0.0 1.5e-24 85.8 0.0 2.1 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EMC88945.1 - 8e-22 77.7 0.0 1.7e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Adaptin_binding PF10199.4 EMC88945.1 - 0.028 14.7 1.5 0.059 13.6 1.0 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Flavodoxin_NdrI PF07972.6 EMC88945.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 NrdI Flavodoxin like Exo_endo_phos_2 PF14529.1 EMC88946.1 - 3.4e-06 26.6 0.0 5.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PDEase_I PF00233.14 EMC88947.1 - 7.1e-42 143.7 0.2 1.2e-37 129.9 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase OATP PF03137.15 EMC88948.1 - 3.1e-53 180.6 12.4 3.7e-53 180.3 8.6 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.10 EMC88948.1 - 5.8e-11 42.1 4.9 1.4e-10 40.9 3.4 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC88948.1 - 0.0013 18.7 5.5 0.0043 17.0 3.8 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Pre-SET PF05033.11 EMC88948.1 - 0.078 13.2 0.7 0.078 13.2 0.5 2.3 1 1 1 2 2 2 0 Pre-SET motif DUF4149 PF13664.1 EMC88948.1 - 6.4 6.9 6.9 1.1 9.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) OATP PF03137.15 EMC88949.1 - 6.3e-92 308.3 3.4 7.4e-92 308.1 2.3 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EMC88949.1 - 6.9e-21 74.3 8.5 8.6e-21 74.0 5.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC88949.1 - 1.5e-06 27.1 2.7 2e-06 26.6 1.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter SNN_linker PF09050.5 EMC88949.1 - 0.13 11.8 0.4 0.29 10.6 0.3 1.6 1 0 0 1 1 1 0 Stannin unstructured linker TLD PF07534.11 EMC88950.1 - 5.8e-28 97.6 0.1 1.4e-15 57.5 0.0 2.4 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.13 EMC88950.1 - 1.2e-22 80.4 0.9 2.2e-22 79.6 0.6 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SNARE PF05739.14 EMC88951.1 - 4.3e-14 51.9 7.0 4.3e-14 51.9 4.8 2.2 2 0 0 2 2 2 1 SNARE domain HD_assoc PF13286.1 EMC88951.1 - 0.025 14.8 0.3 0.8 10.0 0.0 2.4 2 1 0 2 2 2 0 Phosphohydrolase-associated domain Spore_III_AB PF09548.5 EMC88951.1 - 0.03 14.0 0.3 0.03 14.0 0.2 2.1 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DASH_Duo1 PF08651.5 EMC88951.1 - 0.07 12.7 2.6 0.12 11.9 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 Syntaxin-6_N PF09177.6 EMC88951.1 - 0.077 13.4 7.9 0.43 11.0 0.4 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 EMC88951.1 - 0.08 12.7 4.9 0.14 11.9 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4006 PF13179.1 EMC88951.1 - 0.13 11.8 0.3 0.27 10.8 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) IMS_C PF11799.3 EMC88951.1 - 0.15 11.9 1.0 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain Use1 PF09753.4 EMC88951.1 - 0.2 11.0 4.2 0.43 9.9 2.7 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 Sec20 PF03908.8 EMC88951.1 - 0.21 11.3 3.7 0.23 11.2 0.3 2.2 2 0 0 2 2 2 0 Sec20 Synaptobrevin PF00957.16 EMC88951.1 - 0.4 10.3 3.2 0.44 10.1 0.6 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF1664 PF07889.7 EMC88951.1 - 2.3 8.0 6.0 1.7 8.4 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V-SNARE PF05008.10 EMC88951.1 - 2.4 8.4 8.9 0.59 10.3 1.2 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.7 EMC88951.1 - 7.2 6.9 9.3 3.4 7.9 1.7 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PI3K_1B_p101 PF10486.4 EMC88954.1 - 0 1361.5 7.6 2.7e-205 683.6 0.3 2.0 1 1 1 2 2 2 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ARPC4 PF05856.7 EMC88954.1 - 0.012 15.0 1.7 0.41 10.0 1.0 2.7 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) PI3K_1B_p101 PF10486.4 EMC88955.1 - 8e-43 146.1 0.6 2.7e-42 144.3 0.4 1.7 1 1 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TnpW PF14202.1 EMC88955.1 - 0.012 15.1 0.0 0.051 13.1 0.0 2.0 2 0 0 2 2 2 0 Transposon-encoded protein TnpW MFS_1 PF07690.11 EMC88956.1 - 8.7e-12 44.4 32.8 5.7e-11 41.7 13.8 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMC88956.1 - 0.00086 17.8 18.3 0.00086 17.8 12.7 1.9 2 1 0 2 2 2 1 MFS/sugar transport protein DUF3585 PF12130.3 EMC88957.1 - 2.9e-33 114.7 15.4 3.8e-33 114.3 10.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) Hep_59 PF07052.6 EMC88957.1 - 0.0078 16.5 2.8 0.065 13.6 0.2 2.1 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 NACHT PF05729.7 EMC88957.1 - 0.014 15.0 0.4 0.018 14.7 0.3 1.2 1 0 0 1 1 1 0 NACHT domain Histone_HNS PF00816.16 EMC88957.1 - 0.24 11.9 7.3 0.69 10.4 5.1 1.8 1 1 0 1 1 1 0 H-NS histone family Fmp27_WPPW PF10359.4 EMC88957.1 - 0.29 9.4 6.9 0.34 9.2 4.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1027 PF06265.6 EMC88957.1 - 0.49 10.3 2.2 1.4 8.7 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1027) DUF515 PF04415.7 EMC88957.1 - 0.57 8.3 6.0 0.67 8.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Telomere_Sde2 PF13019.1 EMC88957.1 - 1.6 8.3 6.6 0.47 10.1 0.4 2.2 2 0 0 2 2 2 0 Telomere stability and silencing FlxA PF14282.1 EMC88957.1 - 5.4 7.0 10.5 0.48 10.3 2.6 2.1 2 0 0 2 2 2 0 FlxA-like protein Phage_gp53 PF11246.3 EMC88957.1 - 7.6 5.9 7.1 8.1 5.8 0.2 2.0 1 1 1 2 2 2 0 Base plate wedge protein 53 DUF4200 PF13863.1 EMC88959.1 - 1.6e-22 79.7 29.9 1.6e-22 79.7 20.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Hemerythrin PF01814.18 EMC88959.1 - 0.25 11.4 10.8 0.16 12.1 3.1 2.8 1 1 1 3 3 3 0 Hemerythrin HHE cation binding domain UvrD-helicase PF00580.16 EMC88959.1 - 2.7 7.2 21.2 3.8 6.7 14.7 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Barstar PF01337.13 EMC88959.1 - 3.2 7.6 8.5 3.6 7.4 0.3 3.3 2 1 1 3 3 3 0 Barstar (barnase inhibitor) Fib_alpha PF08702.5 EMC88959.1 - 5.1 7.2 26.9 3.4 7.7 7.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-CCHC_2 PF13696.1 EMC88960.1 - 0.0071 15.8 4.0 0.0071 15.8 2.8 2.0 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 EMC88960.1 - 0.069 13.1 15.9 0.43 10.5 4.7 2.6 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EMC88960.1 - 0.18 11.5 9.7 0.23 11.1 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.20 EMC88961.1 - 1.4e-58 198.0 0.0 1.8e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88961.1 - 8.7e-39 133.1 0.0 1.1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC88961.1 - 7.7e-11 41.4 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMC88961.1 - 0.00012 21.0 0.1 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DXP_redisom_C PF08436.7 EMC88961.1 - 0.01 15.7 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal APH PF01636.18 EMC88961.1 - 0.051 13.3 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3110 PF11360.3 EMC88962.1 - 0.036 13.8 0.4 0.18 11.6 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Mitofilin PF09731.4 EMC88962.1 - 7.2 5.1 41.8 0.02 13.6 14.6 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein FMN_dh PF01070.13 EMC88963.1 - 2.5e-135 450.9 0.1 2.8e-135 450.7 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMC88963.1 - 1.1e-05 24.5 0.3 3.4e-05 22.8 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMC88963.1 - 7e-05 21.9 0.1 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EMC88963.1 - 0.00018 20.6 0.5 0.25 10.4 0.1 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EMC88963.1 - 0.00066 19.0 0.2 0.0052 16.0 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 EMC88963.1 - 0.0042 16.0 0.1 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase TMP-TENI PF02581.12 EMC88963.1 - 0.014 14.5 0.5 0.14 11.3 0.0 2.5 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI Dus PF01207.12 EMC88963.1 - 0.02 13.7 0.0 5.5 5.7 0.0 2.3 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) NMO PF03060.10 EMC88963.1 - 0.023 13.8 2.2 0.062 12.4 1.6 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase PA PF02225.17 EMC88963.1 - 0.055 13.1 0.1 12 5.6 0.1 2.6 2 1 1 3 3 3 0 PA domain G3P_antiterm PF04309.7 EMC88963.1 - 0.12 11.3 0.3 7.6 5.5 0.1 2.2 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PI-PLC-X PF00388.14 EMC88964.1 - 2.9e-65 218.1 0.0 2.9e-65 218.1 0.0 2.4 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PLC-beta_C PF08703.5 EMC88964.1 - 5.3e-46 156.6 34.3 5.3e-46 156.6 23.8 2.8 3 0 0 3 3 3 1 PLC-beta C terminal PI-PLC-Y PF00387.14 EMC88964.1 - 8.4e-45 151.5 2.0 8.4e-45 151.5 1.4 3.9 3 1 1 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC88964.1 - 4.6e-24 84.2 0.0 4.6e-24 84.2 0.0 3.2 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-X PF00388.14 EMC88965.1 - 1.9e-66 221.9 0.8 4.1e-66 220.8 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMC88965.1 - 9.6e-45 151.3 0.6 9.6e-45 151.3 0.4 3.8 4 1 1 5 5 5 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC88965.1 - 1.4e-24 85.9 2.5 3.6e-24 84.5 0.1 3.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1154 PF06631.6 EMC88965.1 - 4.7e-19 67.7 11.7 4.7e-19 67.7 8.1 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1154) C2 PF00168.25 EMC88965.1 - 9.1e-11 41.4 0.0 2.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 EMC88965.1 - 0.017 15.2 1.7 0.11 12.6 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EMC88965.1 - 0.075 12.9 0.4 0.31 11.0 0.3 2.1 1 0 0 1 1 1 0 EF-hand domain BCAS3 PF12490.3 EMC88967.1 - 7.6e-31 107.3 0.0 1.9e-30 106.0 0.0 1.5 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.27 EMC88967.1 - 9.5e-06 25.3 0.5 0.00096 18.9 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat PP2C PF00481.16 EMC88968.1 - 1.5e-59 201.4 0.0 2.2e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMC88968.1 - 0.0012 18.3 0.0 0.046 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C TPR_12 PF13424.1 EMC88969.1 - 9.7e-24 83.1 22.2 7.4e-09 35.4 0.7 7.5 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 EMC88969.1 - 2.2e-17 62.3 0.9 4.5e-05 23.2 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC88969.1 - 3.4e-08 32.6 3.8 0.0052 16.4 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMC88969.1 - 1.5e-06 27.7 20.0 0.0029 17.2 2.0 6.4 3 3 3 6 6 6 3 TPR repeat TPR_1 PF00515.23 EMC88969.1 - 3.2e-06 26.5 21.9 0.00028 20.3 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC88969.1 - 1.6e-05 24.4 14.1 2.9 8.0 0.1 7.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC88969.1 - 2.4 8.1 16.8 3.1 7.7 0.1 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Carb_anhydrase PF00194.16 EMC88970.1 - 5e-72 241.9 0.1 5.9e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GSG-1 PF07803.6 EMC88970.1 - 0.014 15.0 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 GSG1-like protein 7tm_1 PF00001.16 EMC88971.1 - 4.9e-31 107.7 17.5 5.7e-31 107.5 12.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2628 PF10947.3 EMC88971.1 - 0.17 11.6 3.3 0.48 10.2 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) 7TM_GPCR_Srsx PF10320.4 EMC88971.1 - 1.9 7.5 17.3 3.3 6.7 12.0 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Myosin_head PF00063.16 EMC88972.1 - 2.9e-195 650.3 0.3 3.5e-195 650.0 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.1 EMC88972.1 - 6.4e-05 23.0 0.3 0.065 13.2 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMC88972.1 - 0.00097 19.2 0.7 0.0061 16.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain IQ PF00612.22 EMC88972.1 - 0.0014 18.1 1.0 0.0014 18.1 0.7 3.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif GWT1 PF06423.7 EMC88973.1 - 4.8e-34 117.3 5.5 4.8e-34 117.3 3.8 2.8 2 1 0 2 2 2 1 GWT1 DUF3096 PF11295.3 EMC88973.1 - 0.033 13.6 2.2 0.23 11.0 1.6 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) BLVR PF06375.6 EMC88974.1 - 9.1 6.0 12.8 6.3 6.5 1.2 2.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) adh_short PF00106.20 EMC88975.1 - 8.2e-15 55.1 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC88975.1 - 5.2e-09 36.2 0.0 6.3e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC88975.1 - 0.0027 17.3 0.0 0.0075 15.9 0.0 1.6 2 0 0 2 2 2 1 KR domain SpoU_methylase PF00588.14 EMC88976.1 - 2.5e-31 108.4 0.0 3e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF4177 PF13783.1 EMC88976.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4177) LIM PF00412.17 EMC88978.1 - 6.7e-33 112.5 17.3 2.5e-16 59.4 0.6 2.3 1 1 1 2 2 2 2 LIM domain Homeobox PF00046.24 EMC88978.1 - 2.8e-10 39.6 0.2 5e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain SpoIIIAH PF12685.2 EMC88978.1 - 0.16 11.4 5.0 0.22 10.9 3.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein AATF-Che1 PF13339.1 EMC88979.1 - 1.9e-37 128.3 0.7 1.9e-37 128.3 0.5 1.9 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EMC88979.1 - 6.5e-29 99.8 0.2 6.5e-29 99.8 0.2 2.2 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal PaREP1 PF05942.6 EMC88979.1 - 0.013 15.3 0.5 0.042 13.7 0.1 2.2 2 1 0 2 2 2 0 Archaeal PaREP1/PaREP8 family DUF1203 PF06718.6 EMC88980.1 - 0.038 13.8 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) SWIRM PF04433.12 EMC88981.1 - 3.3e-15 55.9 0.0 1.3e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EMC88981.1 - 9.2e-10 38.4 0.3 2e-09 37.3 0.1 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMC88981.1 - 2.8e-05 24.1 0.4 0.00015 21.7 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EMC88981.1 - 0.021 14.3 2.3 0.044 13.3 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type RPA_C PF08784.6 EMC88981.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Pedibin PF08182.6 EMC88981.1 - 2.3 7.7 7.4 0.75 9.3 0.1 2.4 2 0 0 2 2 2 0 Pedibin/Hym-346 family DSPc PF00782.15 EMC88982.1 - 4.6e-38 129.8 0.0 5.5e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC88982.1 - 5.4e-06 25.9 0.0 7.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC88982.1 - 0.0008 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMC88982.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family HNF-1B_C PF04812.8 EMC88983.1 - 4.9e-96 320.7 38.5 8.3e-96 319.9 26.7 1.4 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.8 EMC88983.1 - 2.2e-65 220.1 0.5 2.2e-65 220.1 0.4 1.9 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 EMC88983.1 - 1.5e-05 24.5 0.6 1.5e-05 24.5 0.4 2.6 2 1 0 2 2 2 1 Homeobox domain HTH_5 PF01022.15 EMC88983.1 - 0.36 10.5 2.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF4042 PF13251.1 EMC88984.1 - 5.3e-70 234.5 2.7 1.2e-68 230.1 0.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 EMC88984.1 - 3.4e-25 88.1 8.1 2.9e-08 33.8 0.3 7.8 5 1 5 10 10 10 6 HEAT repeats HEAT PF02985.17 EMC88984.1 - 9.8e-17 59.4 18.1 0.00057 19.7 0.0 10.4 12 0 0 12 12 12 5 HEAT repeat HEAT_EZ PF13513.1 EMC88984.1 - 4.5e-16 58.8 17.3 0.017 15.5 0.4 9.4 10 1 1 11 11 11 5 HEAT-like repeat Adaptin_N PF01602.15 EMC88984.1 - 3.3e-07 29.0 0.5 0.031 12.5 0.1 4.7 3 2 2 5 5 5 2 Adaptin N terminal region FANCI_S2 PF14676.1 EMC88984.1 - 0.0029 17.5 1.0 0.54 10.1 0.0 2.9 3 0 0 3 3 3 1 FANCI solenoid 2 Arm PF00514.18 EMC88984.1 - 0.022 14.5 22.6 0.48 10.3 0.1 8.0 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EMC88984.1 - 0.031 14.7 10.2 3 8.5 0.0 6.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Arm_2 PF04826.8 EMC88984.1 - 0.051 12.6 0.9 0.79 8.7 0.0 2.8 3 0 0 3 3 3 0 Armadillo-like Dynein_light PF01221.13 EMC88985.1 - 5.1e-46 154.5 1.7 5.8e-46 154.4 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HEXIM PF15313.1 EMC88985.1 - 0.014 15.5 0.2 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein TraH PF06122.6 EMC88985.1 - 0.037 12.8 0.0 0.041 12.7 0.0 1.0 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein WIYLD PF10440.4 EMC88985.1 - 0.061 13.2 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain HTH_33 PF13592.1 EMC88985.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix UCH PF00443.24 EMC88985.1 - 0.085 11.9 0.1 0.098 11.7 0.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ground-like PF04155.13 EMC88985.1 - 0.088 13.1 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 Ground-like domain Peptidase_C3 PF00548.15 EMC88985.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Ectatomin PF06457.6 EMC88985.1 - 0.14 11.9 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Ectatomin SpoIIIAH PF12685.2 EMC88985.1 - 0.29 10.6 2.2 0.37 10.2 1.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein zf-C2H2 PF00096.21 EMC88987.1 - 1.7e-19 68.9 51.4 0.00023 21.2 1.5 7.1 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC88987.1 - 4.1e-16 58.0 51.7 0.00022 21.3 0.8 6.9 7 0 0 7 7 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC88987.1 - 1.4e-15 56.6 61.6 1.1e-06 28.6 2.0 8.5 9 0 0 9 9 8 4 Zinc-finger double domain zf-Di19 PF05605.7 EMC88987.1 - 0.00065 19.7 31.5 0.29 11.3 4.6 4.6 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Med15 PF09606.5 EMC88987.1 - 0.00073 17.8 42.4 0.0012 17.1 29.4 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal zf-BED PF02892.10 EMC88987.1 - 0.025 14.3 2.1 0.025 14.3 1.5 6.9 4 2 3 7 7 7 0 BED zinc finger Suf PF05843.9 EMC88987.1 - 0.047 13.4 13.1 0.079 12.6 9.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF342 PF03961.8 EMC88987.1 - 0.1 11.0 7.1 0.14 10.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LMBR1 PF04791.11 EMC88987.1 - 0.12 10.9 2.7 0.18 10.3 1.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.1 EMC88987.1 - 0.14 11.1 15.8 0.21 10.5 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SpaB_C PF14028.1 EMC88987.1 - 0.17 11.4 0.2 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain zf-met PF12874.2 EMC88987.1 - 0.18 12.0 0.2 0.18 12.0 0.1 6.5 7 0 0 7 7 6 0 Zinc-finger of C2H2 type AUX_IAA PF02309.11 EMC88987.1 - 0.22 11.2 12.5 0.4 10.4 8.6 1.4 1 0 0 1 1 1 0 AUX/IAA family Dala_Dala_lig_N PF01820.16 EMC88987.1 - 0.29 11.4 5.3 0.58 10.4 3.7 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus CPSF100_C PF13299.1 EMC88987.1 - 0.34 11.0 10.6 0.99 9.5 7.2 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.10 EMC88987.1 - 0.4 9.3 10.2 0.7 8.5 7.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4045 PF13254.1 EMC88987.1 - 0.45 9.7 19.8 0.068 12.4 9.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DZR PF12773.2 EMC88987.1 - 0.52 10.1 22.8 0.67 9.8 0.5 4.8 3 1 1 4 4 4 0 Double zinc ribbon XPA_N PF01286.13 EMC88987.1 - 0.56 9.9 0.1 0.56 9.9 0.0 5.3 7 0 0 7 7 5 0 XPA protein N-terminal AAA_23 PF13476.1 EMC88987.1 - 0.86 9.8 12.6 1.2 9.3 8.7 1.2 1 0 0 1 1 1 0 AAA domain Band_3_cyto PF07565.8 EMC88987.1 - 0.91 8.9 13.2 1.6 8.1 9.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain zf-C2H2_2 PF12756.2 EMC88987.1 - 1.1 9.4 0.0 1.1 9.4 0.0 6.5 2 1 4 6 6 5 0 C2H2 type zinc-finger (2 copies) Pex16 PF08610.5 EMC88987.1 - 1.2 8.0 10.9 2.2 7.1 7.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SID-1_RNA_chan PF13965.1 EMC88987.1 - 1.4 7.0 7.0 1.8 6.5 4.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.12 EMC88987.1 - 1.5 8.5 13.5 0.78 9.4 7.4 1.9 2 0 0 2 2 2 0 DDHD domain FimP PF09766.4 EMC88987.1 - 2 7.3 24.7 3.2 6.7 17.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein Paramyxo_ncap PF00973.14 EMC88987.1 - 2.3 6.8 11.1 3.4 6.2 7.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.7 EMC88987.1 - 2.3 8.0 12.0 4 7.2 8.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.5 EMC88987.1 - 2.8 7.7 11.4 5.1 6.8 7.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4557 PF15101.1 EMC88987.1 - 3 7.6 22.9 5.4 6.7 15.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DHHW PF14286.1 EMC88987.1 - 4.2 6.5 9.8 6.5 5.9 6.8 1.2 1 0 0 1 1 1 0 DHHW protein Ctr PF04145.10 EMC88987.1 - 4.3 7.3 6.6 9.2 6.3 4.6 1.6 1 0 0 1 1 1 0 Ctr copper transporter family AIF_C PF14721.1 EMC88987.1 - 4.3 7.5 9.9 9.2 6.5 6.9 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folate_carrier PF01770.13 EMC88987.1 - 5.7 5.3 8.0 8.5 4.7 5.5 1.2 1 0 0 1 1 1 0 Reduced folate carrier Cellulose_synt PF03552.9 EMC88987.1 - 8.7 4.5 8.1 13 3.9 5.6 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4175 PF13779.1 EMC88987.1 - 9.2 3.8 40.0 13 3.3 27.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM176 PF14851.1 EMC88987.1 - 9.2 5.9 8.9 18 4.9 6.2 1.5 1 0 0 1 1 1 0 FAM176 family DUF1341 PF07071.6 EMC88989.1 - 0.14 11.6 0.5 0.18 11.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1341) MRP-S23 PF10484.4 EMC88990.1 - 6.4e-09 35.7 0.0 7e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 Cir_Bir_Yir PF06022.6 EMC88990.1 - 0.063 12.5 0.2 0.071 12.3 0.2 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir RRM_6 PF14259.1 EMC88991.1 - 0.0093 15.9 0.0 0.021 14.8 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC88991.1 - 0.016 14.8 0.8 0.022 14.3 0.1 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 EMC88991.1 - 0.051 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) TUDOR PF00567.19 EMC88992.1 - 1.7e-19 69.8 0.0 2.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.24 EMC88992.1 - 1.5e-12 46.9 0.0 2.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC88992.1 - 1.2e-05 24.7 0.0 4.1e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 KH domain Agenet PF05641.7 EMC88992.1 - 0.0078 16.3 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Agenet domain KH_4 PF13083.1 EMC88992.1 - 0.023 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 KH domain DUF2708 PF10917.3 EMC88993.1 - 0.0057 16.4 0.2 0.0095 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2708) WD40 PF00400.27 EMC88994.1 - 4.8e-42 140.3 15.3 9.6e-09 34.8 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat SOCS_box PF07525.11 EMC88994.1 - 4.5e-13 48.8 0.4 9.2e-13 47.8 0.3 1.6 1 0 0 1 1 1 1 SOCS box eIF2A PF08662.6 EMC88994.1 - 1.2e-05 25.1 0.0 0.042 13.5 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EMC88994.1 - 0.0015 17.7 0.3 2.8 6.9 0.0 3.2 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EMC88994.1 - 0.0022 17.6 1.3 4.8 6.9 0.1 4.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EMC88994.1 - 0.0028 15.8 0.3 0.013 13.6 0.1 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMC88994.1 - 0.0056 15.0 0.1 0.63 8.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain Pkinase_Tyr PF07714.12 EMC88995.1 - 4.3e-51 173.4 0.0 6.7e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC88995.1 - 1.3e-43 149.0 0.0 2.4e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EMC88995.1 - 9.6e-06 24.7 0.0 1.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.17 EMC88995.1 - 0.00025 20.7 12.4 0.00043 19.9 8.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.17 EMC88995.1 - 0.0021 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMC88995.1 - 0.047 12.7 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC88995.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING-like PF08746.6 EMC88995.1 - 0.076 13.0 7.9 0.18 11.8 5.5 1.6 1 0 0 1 1 1 0 RING-like domain Complex1_LYR PF05347.10 EMC88996.1 - 3.6e-14 52.3 0.9 4.1e-14 52.1 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC88996.1 - 2.1e-13 50.2 0.3 2.5e-13 49.9 0.2 1.0 1 0 0 1 1 1 1 Complex1_LYR-like DUF982 PF06169.7 EMC88996.1 - 0.067 12.9 0.2 0.084 12.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF982) Pkinase PF00069.20 EMC88997.1 - 5.2e-68 229.0 0.0 6.9e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC88997.1 - 4.2e-31 107.9 0.0 6.6e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC88997.1 - 0.00012 21.1 0.0 0.00045 19.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMC88997.1 - 0.0046 16.7 1.7 0.018 14.8 1.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family IFT20 PF14931.1 EMC88999.1 - 3e-32 111.0 8.7 3.3e-32 110.9 6.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 HRDC PF00570.18 EMC88999.1 - 0.024 14.3 1.4 0.032 13.9 1.0 1.2 1 0 0 1 1 1 0 HRDC domain BTB_2 PF02214.17 EMC89000.1 - 1.7e-20 72.9 0.0 3.3e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EMC89000.1 - 2.1e-06 27.7 0.0 4.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EMC89001.1 - 4.9e-87 283.0 18.6 4.3e-14 51.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMC89001.1 - 1.6e-12 46.3 12.2 0.0049 15.0 0.0 6.5 2 2 5 7 7 7 5 Nucleoporin Nup120/160 LisH PF08513.6 EMC89001.1 - 9.9e-09 34.6 0.4 2.3e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 EMC89001.1 - 1.2e-05 24.3 0.5 0.77 8.4 0.0 4.4 1 1 3 4 4 4 2 Nup133 N terminal like Rav1p_C PF12234.3 EMC89001.1 - 0.012 13.7 0.1 0.05 11.7 0.0 1.8 2 0 0 2 2 2 0 RAVE protein 1 C terminal Pox_A_type_inc PF04508.7 EMC89001.1 - 0.037 13.8 0.4 0.037 13.8 0.3 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 EMC89001.1 - 0.12 12.6 1.5 0.21 11.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CCDC92 PF14916.1 EMC89002.1 - 3.7e-16 58.4 14.0 3.7e-16 58.4 9.7 2.3 1 1 1 2 2 2 1 Coiled-coil domain of unknown function CENP-P PF13096.1 EMC89002.1 - 0.042 13.1 1.6 0.055 12.7 1.1 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUF2702 PF10863.3 EMC89002.1 - 0.08 12.6 2.6 0.16 11.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2702) DCD PF06559.6 EMC89002.1 - 0.14 10.4 0.9 0.18 10.1 0.6 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DivIC PF04977.10 EMC89002.1 - 0.75 9.3 16.4 3 7.3 2.1 3.3 1 1 1 2 2 2 0 Septum formation initiator FlxA PF14282.1 EMC89002.1 - 0.77 9.7 14.7 0.85 9.6 3.5 2.5 1 1 1 2 2 2 0 FlxA-like protein DUF1311 PF07007.7 EMC89002.1 - 0.89 9.6 7.3 2.3 8.3 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1311) FlaC_arch PF05377.6 EMC89002.1 - 1.2 9.0 6.9 3.7 7.5 0.8 3.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Tox-ODYAM1 PF15642.1 EMC89002.1 - 1.6 7.3 9.2 1.8 7.1 6.4 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TPD52 PF04201.10 EMC89002.1 - 2.2 7.9 16.2 1.1 8.9 5.8 2.4 1 1 1 2 2 2 0 Tumour protein D52 family Peptidase_S49_N PF08496.5 EMC89002.1 - 3.2 7.5 8.0 4.4 7.0 5.5 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Spc7 PF08317.6 EMC89002.1 - 5.9 5.4 17.2 7.4 5.1 11.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1515 PF07439.6 EMC89002.1 - 8.3 6.2 6.6 2.4 8.0 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) WSC PF01822.14 EMC89004.1 - 1.6e-20 72.7 12.6 7.3e-13 48.2 0.6 2.5 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.22 EMC89004.1 - 1.8e-08 34.0 0.5 2.7e-08 33.3 0.2 1.5 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC89004.1 - 0.01 16.7 0.1 0.027 15.4 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family DUF164 PF02591.10 EMC89005.1 - 1.9 8.3 0.0 1.9 8.3 0.0 4.2 3 1 1 4 4 4 0 Putative zinc ribbon domain DUF3371 PF11851.3 EMC89005.1 - 7.9 7.1 8.7 23 5.6 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3371) Na_sulph_symp PF00939.14 EMC89006.1 - 6.9e-116 387.8 28.1 8.5e-116 387.5 19.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMC89006.1 - 2.4e-17 62.5 39.7 2.4e-06 26.3 7.5 3.2 3 0 0 3 3 3 3 Citrate transporter UPF0121 PF03661.8 EMC89006.1 - 2.7 7.1 9.3 1.8 7.6 4.9 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Med31 PF05669.7 EMC89007.1 - 5.2e-43 144.9 9.2 6.9e-43 144.5 6.4 1.1 1 0 0 1 1 1 1 SOH1 DUF953 PF06110.6 EMC89008.1 - 1.1e-27 95.7 0.0 1.3e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) DDHD PF02862.12 EMC89010.1 - 1.2e-46 159.3 0.0 2.7e-46 158.2 0.0 1.6 1 0 0 1 1 1 1 DDHD domain LNS2 PF08235.8 EMC89010.1 - 1.2e-37 128.9 0.1 2e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.9 EMC89010.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) CH PF00307.26 EMC89011.1 - 2.4e-17 62.9 0.1 3.8e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMC89011.1 - 9.8e-06 25.1 0.1 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain F-box-like PF12937.2 EMC89012.1 - 6e-08 32.2 3.1 6e-08 32.2 2.1 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMC89012.1 - 5.8e-06 25.8 0.3 5.8e-06 25.8 0.2 2.9 4 0 0 4 4 4 1 F-box domain DUF1466 PF07326.6 EMC89013.1 - 1e-13 51.1 2.2 1.2e-13 50.9 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1466) DUF4349 PF14257.1 EMC89013.1 - 0.098 11.8 0.2 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1117 PF06547.7 EMC89013.1 - 0.62 10.1 2.6 0.58 10.2 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Glyco_transf_22 PF03901.12 EMC89014.1 - 6.3e-28 97.9 33.2 1.8e-27 96.4 23.0 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family zf-BED PF02892.10 EMC89015.1 - 3.6e-59 196.3 27.3 1.6e-15 56.5 0.2 4.5 4 0 0 4 4 4 4 BED zinc finger Dimer_Tnp_hAT PF05699.9 EMC89015.1 - 8.1e-11 41.4 3.5 9.2e-11 41.2 0.4 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PyrI_C PF02748.10 EMC89015.1 - 0.015 14.7 5.3 6.1 6.3 0.0 4.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4413 PF14372.1 EMC89015.1 - 0.056 13.4 1.1 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) TAFA PF12020.3 EMC89018.1 - 2.6e-12 46.6 0.6 3.1e-12 46.4 0.4 1.1 1 0 0 1 1 1 1 TAFA family RabGAP-TBC PF00566.13 EMC89019.1 - 6.2e-49 166.3 1.6 6.2e-49 166.3 1.1 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DAGK_cat PF00781.19 EMC89020.1 - 5.4e-25 87.3 0.0 9e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain tRNA_anti-codon PF01336.20 EMC89022.1 - 2.4e-07 30.4 0.0 6.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain ICL PF00463.16 EMC89022.1 - 0.06 11.5 0.3 0.07 11.3 0.2 1.1 1 0 0 1 1 1 0 Isocitrate lyase family zf-H2C2_2 PF13465.1 EMC89023.1 - 2.7e-54 178.9 69.3 1.7e-08 34.3 0.6 10.6 11 0 0 11 11 10 10 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89023.1 - 3.2e-44 146.6 80.2 1.5e-06 28.1 0.2 10.1 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89023.1 - 2.2e-24 83.9 73.9 9.8e-05 22.4 0.6 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC89023.1 - 1e-16 60.1 53.1 0.0067 16.2 0.1 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger LIM PF00412.17 EMC89023.1 - 9.1e-08 32.0 46.3 0.31 11.1 2.0 8.6 5 2 4 9 9 9 6 LIM domain zf-LYAR PF08790.6 EMC89023.1 - 2.1e-07 30.4 57.4 0.76 9.5 0.2 9.9 10 0 0 10 10 10 6 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EMC89023.1 - 5.8e-06 25.8 44.6 0.29 10.7 0.1 10.0 10 0 0 10 10 10 3 Probable zinc-binding domain SAS4 PF15460.1 EMC89023.1 - 0.022 14.6 0.1 43 4.0 0.0 3.6 2 2 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 BolA PF01722.13 EMC89023.1 - 0.036 14.0 11.2 1 9.3 0.3 4.6 3 2 2 5 5 5 0 BolA-like protein zf-met PF12874.2 EMC89023.1 - 0.037 14.2 2.3 0.33 11.2 0.1 8.8 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EMC89023.1 - 0.039 13.6 0.4 0.039 13.6 0.3 7.8 10 0 0 10 10 10 0 zinc-finger of a C2HC-type DUF1635 PF07795.6 EMC89023.1 - 0.076 12.3 2.7 64 2.8 0.0 4.5 2 1 4 6 6 6 0 Protein of unknown function (DUF1635) RRN7 PF11781.3 EMC89023.1 - 0.16 11.5 27.7 0.17 11.4 0.3 8.2 10 0 0 10 10 9 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 EMC89023.1 - 0.31 11.2 46.1 0.52 10.5 0.1 8.7 10 0 0 10 10 8 0 Zinc-finger double-stranded RNA-binding Ricin_B_lectin PF00652.17 EMC89023.1 - 0.76 9.8 12.6 0.12 12.4 2.2 3.1 1 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain Zn-ribbon_8 PF09723.5 EMC89023.1 - 1 9.3 55.6 1.7 8.6 2.3 9.2 4 2 6 10 10 10 0 Zinc ribbon domain Crust_neurohorm PF01147.12 EMC89023.1 - 1.7 8.0 23.9 26 4.2 0.0 7.0 6 1 0 7 7 7 0 Crustacean CHH/MIH/GIH neurohormone family CpXC PF14353.1 EMC89023.1 - 1.7 8.5 34.8 2.6 7.9 2.1 7.5 3 2 4 7 7 6 0 CpXC protein DUF899 PF05988.7 EMC89023.1 - 3.8 6.8 11.7 8.3 5.7 0.7 3.8 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF899) PHF5 PF03660.9 EMC89023.1 - 3.9 7.5 25.4 1.5 8.9 1.6 4.7 1 1 6 7 7 7 0 PHF5-like protein XPA_N PF01286.13 EMC89023.1 - 4.7 6.9 43.5 4 7.2 0.1 9.5 10 0 0 10 10 10 0 XPA protein N-terminal Phageshock_PspG PF09583.5 EMC89024.1 - 4.4 7.4 7.0 23 5.1 4.9 2.1 1 1 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) Pyr_redox_dim PF02852.17 EMC89025.1 - 7.2e-05 22.7 1.0 69 3.5 0.0 6.2 5 1 1 7 7 7 3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain hEGF PF12661.2 EMC89025.1 - 4.7 7.5 12.7 2e+02 2.4 0.0 6.8 7 0 0 7 7 7 0 Human growth factor-like EGF UQ_con PF00179.21 EMC89027.1 - 3.6e-32 110.7 0.3 4.6e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMC89027.1 - 0.059 13.1 0.1 0.3 10.8 0.1 2.1 1 1 0 1 1 1 0 Prokaryotic E2 family B Nrap PF03813.9 EMC89028.1 - 4e-243 809.1 0.0 4.8e-243 808.8 0.0 1.1 1 0 0 1 1 1 1 Nrap protein MIP PF00230.15 EMC89029.1 - 2.3e-52 177.7 11.6 2.9e-52 177.4 8.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein PLA2_inh PF02988.10 EMC89030.1 - 3.2e-20 72.3 21.4 9.1e-18 64.4 6.5 2.1 2 0 0 2 2 2 2 Phospholipase A2 inhibitor UPAR_LY6 PF00021.16 EMC89030.1 - 1.8e-11 44.2 21.8 7.8e-07 29.4 3.3 2.1 2 0 0 2 2 2 2 u-PAR/Ly-6 domain MIP PF00230.15 EMC89031.1 - 5.3e-45 153.6 11.8 6.5e-45 153.3 8.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3172 PF11371.3 EMC89031.1 - 0.061 12.8 0.1 0.061 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) KIAA1328 PF15369.1 EMC89033.1 - 4.5e-141 470.3 41.7 6.1e-141 469.9 28.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein KIAA1328 Endonuc_BglI PF14562.1 EMC89033.1 - 0.049 12.4 0.4 0.085 11.6 0.3 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglI ERM PF00769.14 EMC89033.1 - 0.57 9.6 26.2 0.024 14.1 7.6 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Mod_r PF07200.8 EMC89033.1 - 1.4 8.8 25.8 0.62 9.9 7.8 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GDNF PF02351.11 EMC89033.1 - 2.9 8.4 14.9 0.65 10.5 6.1 2.7 2 0 0 2 2 2 0 GDNF/GAS1 domain APG6 PF04111.7 EMC89033.1 - 3.1 6.7 22.4 3.9 6.4 1.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 RRM_1 PF00076.17 EMC89034.1 - 3.5e-37 125.8 0.0 2.2e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89034.1 - 3.1e-27 94.3 0.1 1.1e-12 47.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89034.1 - 2.8e-23 81.5 0.2 3e-10 39.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EMC89034.1 - 0.00039 20.3 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA binding domain RRM_3 PF08777.6 EMC89034.1 - 0.0098 15.7 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EMC89034.1 - 0.013 15.2 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EMC89035.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89035.1 - 0.04 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC37_C PF08564.5 EMC89036.1 - 4.1e-26 90.7 0.0 4.1e-26 90.7 0.0 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain CDC37_M PF08565.6 EMC89036.1 - 9.1e-24 83.8 6.1 4.7e-17 61.9 0.8 2.4 2 1 0 2 2 2 2 Cdc37 Hsp90 binding domain Arb1 PF09692.5 EMC89036.1 - 0.079 11.7 2.9 0.062 12.1 0.6 1.7 2 0 0 2 2 2 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PDEase_I PF00233.14 EMC89038.1 - 5.8e-50 170.2 0.3 6.4e-50 170.1 0.2 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Kelch_1 PF01344.20 EMC89039.1 - 3.6e-38 128.8 3.9 1.1e-15 56.8 0.1 4.3 4 0 0 4 4 4 4 Kelch motif BACK PF07707.10 EMC89039.1 - 1.3e-32 111.6 1.1 1.3e-32 111.6 0.8 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 EMC89039.1 - 2.9e-27 94.8 0.0 5.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 EMC89039.1 - 5.8e-24 83.2 3.7 5.2e-08 32.7 0.0 4.3 1 1 3 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EMC89039.1 - 2.8e-11 42.9 2.9 0.00097 18.8 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC89039.1 - 2.3e-09 37.1 5.7 0.046 13.8 0.1 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC89039.1 - 5.7e-09 35.3 0.7 0.032 14.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EMC89039.1 - 0.0015 18.3 7.9 0.092 12.7 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Galactosyl_T PF01762.16 EMC89040.1 - 9.2e-46 155.9 0.0 9.8e-29 100.3 0.0 2.0 1 1 1 2 2 2 2 Galactosyltransferase rRNA_processing PF08524.6 EMC89042.1 - 5e-05 23.1 6.9 5e-05 23.1 4.8 2.3 2 0 0 2 2 2 1 rRNA processing DNA_photolyase PF00875.13 EMC89042.1 - 0.22 11.2 2.0 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 DNA photolyase Arrestin_C PF02752.17 EMC89043.1 - 3.7e-20 72.4 0.0 1.6e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMC89043.1 - 9.2e-20 70.9 0.1 5e-18 65.3 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EMC89043.1 - 0.031 13.7 0.0 0.076 12.4 0.0 1.8 1 0 0 1 1 1 0 Arrestin_N terminal like 7tm_1 PF00001.16 EMC89044.1 - 2.1e-33 115.5 18.4 2.4e-33 115.3 12.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Scs3p PF10261.4 EMC89044.1 - 0.6 9.0 8.2 0.55 9.2 2.1 2.1 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2516 PF10724.4 EMC89044.1 - 0.95 9.4 5.0 0.47 10.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) CbiQ PF02361.11 EMC89044.1 - 9.4 5.7 12.1 56 3.1 8.4 2.0 1 1 0 1 1 1 0 Cobalt transport protein AMP-binding PF00501.23 EMC89046.1 - 3.2e-74 249.7 2.1 8e-50 169.4 0.2 2.4 2 0 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 EMC89046.1 - 4e-25 88.5 0.7 8.1e-25 87.5 0.5 1.5 1 0 0 1 1 1 1 DMAP1-binding Domain Macoilin PF09726.4 EMC89046.1 - 0.65 8.2 7.4 0.95 7.6 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein S_100 PF01023.14 EMC89047.1 - 1.9e-20 71.8 1.8 3e-20 71.2 1.2 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 EMC89047.1 - 0.00028 20.9 0.9 0.00039 20.4 0.6 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMC89047.1 - 0.00085 18.4 0.4 0.00085 18.4 0.2 2.4 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 EMC89047.1 - 0.018 14.7 0.7 0.022 14.4 0.5 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Leuk-A4-hydro_C PF09127.6 EMC89047.1 - 0.035 13.7 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal EF-hand_8 PF13833.1 EMC89047.1 - 0.052 13.1 1.3 0.088 12.4 0.9 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EMC89047.1 - 0.053 13.4 0.6 1.9 8.5 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain Prenyltrans_2 PF13249.1 EMC89048.1 - 5.4e-30 104.1 3.0 5.3e-15 55.8 0.1 4.3 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans PF00432.16 EMC89048.1 - 2.1e-23 81.5 7.3 1.1e-10 40.8 0.3 4.7 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EMC89048.1 - 1.3e-18 67.0 0.1 5.9e-07 29.4 0.0 4.2 2 1 4 6 6 6 3 Prenyltransferase-like Pec_lyase PF09492.5 EMC89048.1 - 1.3e-06 27.8 0.0 0.58 9.2 0.0 4.0 4 1 1 5 5 5 3 Pectic acid lyase WD40 PF00400.27 EMC89049.1 - 8.9e-53 174.3 30.7 2.9e-10 39.5 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 EMC89049.1 - 0.00098 19.0 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain DUF4206 PF13901.1 EMC89050.1 - 1.1e-74 250.3 10.9 2e-74 249.5 6.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4206) PH PF00169.24 EMC89050.1 - 4e-14 52.6 0.2 2.2e-09 37.4 0.0 2.7 2 0 0 2 2 2 2 PH domain Frizzled PF01534.12 EMC89051.1 - 5.2e-105 350.8 5.3 6.5e-105 350.5 3.7 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 EMC89051.1 - 0.14 11.0 7.5 0.0071 15.2 1.7 1.4 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor DUF2975 PF11188.3 EMC89051.1 - 0.15 11.8 2.9 0.12 12.1 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Cyclin_N PF00134.18 EMC89052.1 - 1.9e-15 56.5 0.3 3.3e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EMC89052.1 - 4.6e-12 46.5 0.5 6.6e-12 46.0 0.1 1.5 2 0 0 2 2 2 1 Cyclin Methyltransf_16 PF10294.4 EMC89053.1 - 2.3e-35 121.5 0.0 2.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMC89053.1 - 3.8e-05 24.2 0.0 6.3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMC89053.1 - 5.2e-05 22.5 0.0 6.2e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMC89053.1 - 7.5e-05 22.1 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMC89053.1 - 0.00041 20.0 0.0 0.00051 19.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMC89053.1 - 0.031 14.3 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMC89053.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain pKID PF02173.12 EMC89054.1 - 1.6e-21 75.2 2.7 3.9e-21 73.9 1.8 1.7 1 0 0 1 1 1 1 pKID domain bZIP_1 PF00170.16 EMC89054.1 - 8.8e-20 70.4 12.1 1.4e-19 69.7 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC89054.1 - 4.7e-07 29.5 12.1 1.1e-06 28.3 8.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC89054.1 - 0.0021 18.2 5.6 0.0064 16.7 3.9 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor zf-H2C2_2 PF13465.1 EMC89055.1 - 1.6e-10 40.7 21.1 9.8e-06 25.6 0.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89055.1 - 4.8e-07 29.7 22.7 0.00041 20.5 0.4 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89055.1 - 3.4e-05 23.8 19.4 0.0037 17.5 0.9 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC89055.1 - 0.24 11.6 0.1 0.24 11.6 0.0 3.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Peptidase_M14 PF00246.19 EMC89056.1 - 1.2e-82 277.7 0.4 1.4e-82 277.4 0.3 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMC89056.1 - 1.7e-13 50.0 1.1 3.4e-13 49.0 0.8 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF1642 PF07852.6 EMC89056.1 - 5.1e-05 23.6 0.1 0.00012 22.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1642) FAST_2 PF08368.7 EMC89057.1 - 1.4e-12 47.7 0.7 8.2e-12 45.3 0.0 2.5 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.10 EMC89057.1 - 5.5e-09 35.6 9.9 2.4e-08 33.5 0.2 4.8 4 2 2 6 6 6 1 FAST kinase-like protein, subdomain 1 RAP PF08373.5 EMC89057.1 - 2e-07 30.6 0.0 4.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RAP domain Ldh_1_C PF02866.13 EMC89058.1 - 1.6e-09 37.7 0.0 1.4e-08 34.6 0.0 2.3 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain EF-hand_3 PF09069.6 EMC89059.1 - 9.3e-19 67.2 0.0 1.3e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand EF-hand_2 PF09068.6 EMC89059.1 - 0.0028 17.7 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 EF hand Inh PF02974.9 EMC89060.1 - 0.094 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protease inhibitor Inh zf-DBF PF07535.7 EMC89062.1 - 4.6e-08 32.5 6.8 1.1e-07 31.4 4.7 1.6 1 0 0 1 1 1 1 DBF zinc finger 7tm_1 PF00001.16 EMC89063.1 - 4.3e-49 166.9 24.2 5.9e-49 166.5 16.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC89063.1 - 0.0003 20.0 5.0 0.0003 20.0 3.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF788 PF05620.6 EMC89063.1 - 1.4 8.7 6.9 3.8 7.3 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) EF1_GNE PF00736.14 EMC89064.1 - 1.5e-35 120.7 0.4 2.5e-35 120.0 0.3 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EMC89064.1 - 1e-13 51.1 9.6 3.9e-13 49.2 6.7 2.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EMC89064.1 - 0.0063 16.9 0.1 0.019 15.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC89064.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Molybdopterin PF00384.17 EMC89065.1 - 2.9e-75 253.6 0.0 1.9e-74 250.9 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EMC89065.1 - 1e-18 66.2 0.1 2.4e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EMC89065.1 - 1.7e-17 62.9 0.1 4.4e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EMC89065.1 - 3.2e-16 59.1 0.1 6.8e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EMC89065.1 - 1.9e-09 37.1 0.5 1.9e-09 37.1 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EMC89065.1 - 0.01 15.5 0.5 0.92 9.2 0.1 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-C3Hc3H PF13891.1 EMC89066.1 - 1.9e-20 72.6 5.6 5.5e-20 71.1 3.9 1.8 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.6 EMC89066.1 - 0.067 12.8 0.1 0.067 12.8 0.1 2.4 2 0 0 2 2 2 0 Primase zinc finger CUB PF00431.15 EMC89067.1 - 1.2e-61 205.5 0.0 1.8e-29 101.9 0.0 2.6 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.20 EMC89067.1 - 4.6e-53 178.4 2.3 5.9e-27 94.0 0.8 2.5 2 0 0 2 2 2 2 F5/8 type C domain MAM PF00629.18 EMC89067.1 - 1.2e-33 116.1 0.2 3.3e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 MAM domain DUF3481 PF11980.3 EMC89067.1 - 2.1e-24 85.1 0.1 4.1e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) PDZ PF00595.19 EMC89068.1 - 5.6e-38 128.9 4.2 1.4e-17 63.5 0.1 3.8 4 0 0 4 4 4 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC89068.1 - 1.1e-15 57.3 0.1 4.5e-08 32.8 0.0 3.4 3 0 0 3 3 3 2 PDZ domain MIP-T3 PF10243.4 EMC89068.1 - 1.8 6.9 29.2 2.6 6.4 20.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_DNAp_acc PF04929.7 EMC89068.1 - 5.8 5.7 11.3 11 4.8 7.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3534 PF12053.3 EMC89069.1 - 1.9e-14 53.7 0.0 2e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3534) FAM176 PF14851.1 EMC89070.1 - 0.074 12.7 0.7 0.12 12.0 0.5 1.3 1 0 0 1 1 1 0 FAM176 family DUF3609 PF12259.3 EMC89070.1 - 0.17 10.5 2.8 0.27 9.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) EphA2_TM PF14575.1 EMC89070.1 - 0.17 12.2 0.9 0.99 9.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain V-set PF07686.12 EMC89071.1 - 2e-11 43.7 0.0 3.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain stn_TNFRSF12A PF12191.3 EMC89071.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.11 EMC89071.1 - 0.029 12.6 0.0 0.43 8.7 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ig_3 PF13927.1 EMC89071.1 - 0.029 14.8 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 EMC89071.1 - 0.045 13.6 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.12 EMC89072.1 - 5e-05 23.1 0.5 0.0001 22.1 0.4 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain PsbJ PF01788.12 EMC89072.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 PsbJ RA PF00788.18 EMC89073.1 - 1.3e-13 51.2 2.5 3.6e-13 49.8 0.1 2.7 2 1 1 3 3 3 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 EMC89073.1 - 7.2e-09 35.7 0.1 2.1e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 PH domain FERM_N PF09379.5 EMC89073.1 - 0.0033 17.4 0.2 0.0095 15.9 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain Abi_HHR PF07815.9 EMC89074.1 - 1.4e-34 117.9 0.1 2.8e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.1 EMC89074.1 - 1.2e-17 63.1 0.2 2.1e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC89074.1 - 1.7e-16 59.3 0.2 2.6e-16 58.7 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC89074.1 - 1.4e-12 46.9 0.1 2.9e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.17 EMC89075.1 - 1.7e-47 162.0 0.1 2.1e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S51 PF03575.12 EMC89076.1 - 1.3e-44 151.6 0.0 1.5e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 CDC14 PF08045.6 EMC89078.1 - 0.00028 20.0 2.7 0.25 10.4 0.1 3.2 2 1 0 3 3 3 2 Cell division control protein 14, SIN component DUF1148 PF06618.6 EMC89078.1 - 0.088 12.7 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1148) ROKNT PF08067.6 EMC89079.1 - 0.022 14.5 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 ROKNT (NUC014) domain Iso_dh PF00180.15 EMC89080.1 - 4.3e-78 262.6 0.0 5.2e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.3 EMC89080.1 - 0.1 12.6 0.4 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) PIP5K PF01504.13 EMC89081.1 - 8.3e-66 221.6 0.4 1.8e-65 220.5 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EMC89081.1 - 3.1e-30 105.2 0.2 5.4e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EMC89081.1 - 2.7e-16 59.2 14.1 2.7e-16 59.2 9.8 2.2 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.16 EMC89081.1 - 0.00017 21.2 0.0 0.00056 19.6 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Thioredoxin PF00085.15 EMC89082.1 - 4.1e-94 309.1 0.0 5e-25 87.1 0.1 5.7 6 0 0 6 6 6 4 Thioredoxin DnaJ PF00226.26 EMC89082.1 - 3.9e-23 80.9 3.1 7.3e-23 80.0 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_8 PF13905.1 EMC89082.1 - 6.4e-18 64.6 3.0 0.0025 17.8 0.0 5.6 5 1 1 6 6 6 4 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC89082.1 - 5.9e-17 61.8 3.3 0.0053 16.9 0.0 6.6 4 3 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EMC89082.1 - 9.4e-15 54.8 0.0 8e-05 22.5 0.0 3.8 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC89082.1 - 1.9e-11 43.8 3.6 0.033 14.2 0.1 4.7 4 0 0 4 4 4 3 Thioredoxin-like Redoxin PF08534.5 EMC89082.1 - 2.4e-08 33.6 3.2 0.06 12.8 0.0 4.0 4 0 0 4 4 4 3 Redoxin AhpC-TSA PF00578.16 EMC89082.1 - 5e-07 29.4 4.4 0.53 9.9 0.0 4.8 5 0 0 5 5 5 3 AhpC/TSA family Thioredoxin_9 PF14595.1 EMC89082.1 - 8.2e-06 25.4 0.6 1.1 8.8 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_3 PF13192.1 EMC89082.1 - 0.015 15.1 0.0 2.6 7.9 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain Calsequestrin PF01216.12 EMC89082.1 - 0.016 13.9 0.0 3 6.5 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin RMMBL PF07521.7 EMC89082.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Thioredoxin_4 PF13462.1 EMC89082.1 - 0.028 14.4 0.8 6.5 6.7 0.0 3.9 3 1 1 4 4 4 0 Thioredoxin DUF3228 PF11539.3 EMC89082.1 - 0.09 11.8 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) HyaE PF07449.6 EMC89082.1 - 0.13 12.1 0.0 29 4.6 0.0 2.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Pkinase PF00069.20 EMC89083.1 - 4.2e-64 216.1 0.0 5.2e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89083.1 - 8.2e-36 123.4 0.0 1.1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC89083.1 - 0.0045 16.0 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMC89083.1 - 0.064 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EMC89083.1 - 0.097 12.3 0.1 0.26 10.9 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.20 EMC89084.1 - 2e-45 155.3 0.0 2.1e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.2 EMC89086.1 - 3.8e-196 636.1 63.1 1.7e-24 85.9 0.3 13.7 2 2 10 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 EMC89086.1 - 9.4e-196 624.7 75.0 5.6e-10 38.5 0.5 28.2 28 0 0 28 28 28 27 Ankyrin repeat Ank_4 PF13637.1 EMC89086.1 - 5.3e-159 514.1 52.7 6.1e-15 55.2 0.2 21.5 6 5 17 23 23 23 23 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC89086.1 - 2e-140 453.6 71.6 7.3e-10 38.7 0.5 23.5 5 4 20 25 25 25 23 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89086.1 - 1.2e-121 384.1 63.0 3.5e-08 32.9 0.1 27.9 28 0 0 28 28 28 24 Ankyrin repeat Ribosomal_S6 PF01250.12 EMC89086.1 - 0.046 13.5 0.0 4.6 7.1 0.0 3.5 3 1 1 4 4 4 0 Ribosomal protein S6 SF3b1 PF08920.5 EMC89087.1 - 3.4e-42 143.9 30.5 6.9e-39 133.2 7.3 4.5 1 1 2 3 3 3 3 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EMC89087.1 - 4e-11 43.0 3.4 0.0018 18.4 0.0 6.4 5 2 3 8 8 7 3 HEAT repeats HEAT PF02985.17 EMC89087.1 - 9.2e-10 37.7 3.9 0.32 11.1 0.0 8.7 9 0 0 9 9 8 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EMC89087.1 - 8.2e-06 26.1 0.5 1.3 9.4 0.0 4.5 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC89087.1 - 8.7e-06 26.0 3.0 1.5 9.4 0.0 7.4 8 1 1 9 9 9 1 HEAT-like repeat TIP120 PF08623.5 EMC89087.1 - 0.0011 18.5 0.2 0.11 12.1 0.0 2.9 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.3 EMC89087.1 - 0.0027 17.1 0.8 3.3 6.9 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal Adaptin_N PF01602.15 EMC89087.1 - 0.015 13.6 3.0 0.31 9.3 2.0 2.8 1 1 0 1 1 1 0 Adaptin N terminal region Arm PF00514.18 EMC89087.1 - 0.028 14.2 1.4 10 6.1 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4047 PF13256.1 EMC89087.1 - 0.053 13.4 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) UME PF08064.8 EMC89087.1 - 0.13 12.2 0.0 2.6 8.0 0.0 3.3 3 1 1 4 4 3 0 UME (NUC010) domain Polyketide_cyc PF03364.15 EMC89088.1 - 8.3e-11 41.9 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Cpn60_TCP1 PF00118.19 EMC89089.1 - 4.9e-112 375.0 12.5 5.5e-112 374.8 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EMC89089.1 - 0.24 11.0 3.0 0.68 9.6 0.2 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) Cpn10 PF00166.16 EMC89090.1 - 1.5e-24 85.7 0.5 1.7e-24 85.5 0.4 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Mob1_phocein PF03637.12 EMC89091.1 - 5.9e-60 201.9 1.1 6.8e-60 201.7 0.8 1.0 1 0 0 1 1 1 1 Mob1/phocein family Raftlin PF15250.1 EMC89092.1 - 1.6e-192 640.1 0.0 1.9e-192 639.8 0.0 1.0 1 0 0 1 1 1 1 Raftlin RRM_1 PF00076.17 EMC89093.1 - 3.6e-20 71.3 0.7 5.9e-20 70.6 0.5 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89093.1 - 4.5e-18 64.9 0.1 7.1e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89093.1 - 1.6e-09 37.4 0.1 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMC89093.1 - 0.00014 21.6 0.2 0.00021 21.0 0.1 1.2 1 0 0 1 1 1 1 RNA binding motif PI-PLC-X PF00388.14 EMC89094.1 - 1.7e-50 170.2 0.1 3.8e-50 169.0 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMC89094.1 - 3.8e-45 152.6 0.1 8.5e-45 151.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMC89094.1 - 2.8e-24 84.9 0.1 7.3e-24 83.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EMC89094.1 - 5.2e-18 64.6 0.0 1.3e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 EMC89094.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_7 PF13499.1 EMC89094.1 - 0.011 15.8 0.5 1.4 9.1 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair PH PF00169.24 EMC89094.1 - 0.037 14.2 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 PH domain UPF0565 PF10561.4 EMC89095.1 - 1e-82 277.4 0.1 1.2e-82 277.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Cupin_8 PF13621.1 EMC89096.1 - 3.2e-42 144.7 0.0 4e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMC89096.1 - 2.8e-11 43.2 0.1 4.1e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein DUF1493 PF07377.7 EMC89096.1 - 0.033 14.2 0.7 0.081 13.0 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) JmjC PF02373.17 EMC89096.1 - 0.046 13.9 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Sox_N PF12444.3 EMC89097.1 - 3.3e-06 28.0 0.0 8.1 7.6 0.0 5.8 6 1 1 7 7 7 2 Sox developmental protein N terminal Orthopox_A36R PF05950.6 EMC89097.1 - 0.0043 17.0 3.3 1.3 8.9 0.0 4.0 2 2 2 4 4 4 1 Orthopoxvirus A36R protein OTU PF02338.14 EMC89097.1 - 0.088 13.3 19.9 9.3 6.8 0.1 7.6 6 4 1 7 7 7 0 OTU-like cysteine protease Tom5 PF10642.4 EMC89097.1 - 0.1 12.2 7.6 65 3.2 0.0 5.8 4 3 4 8 8 8 0 Mitochondrial import receptor subunit or translocase DUF308 PF03729.8 EMC89097.1 - 2.5 8.1 18.5 5.2 7.1 0.1 5.2 1 1 5 6 6 6 0 Short repeat of unknown function (DUF308) zf-H2C2_2 PF13465.1 EMC89098.1 - 1.2e-92 299.9 84.9 1.1e-08 34.8 0.5 12.1 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89098.1 - 1.7e-54 178.9 129.6 1.7e-06 27.9 3.7 12.6 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89098.1 - 1.5e-34 115.7 110.8 0.00048 20.2 0.7 12.3 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC89098.1 - 1.3e-11 44.0 91.9 0.0022 17.8 1.4 12.2 12 0 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89098.1 - 0.0074 16.4 51.2 0.19 11.9 0.0 9.6 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 EMC89098.1 - 0.016 14.9 50.4 0.3 10.8 0.8 8.1 1 1 8 9 9 9 0 Transcription elongation factor Elf1 like DUF2664 PF10867.3 EMC89098.1 - 0.024 15.2 15.7 1.5 9.4 0.0 5.7 5 1 1 6 6 6 0 Protein of unknown function (DUF2664) LIM PF00412.17 EMC89098.1 - 0.11 12.6 57.3 0.51 10.4 3.6 8.6 2 2 8 10 10 10 0 LIM domain zf-CHCC PF10276.4 EMC89098.1 - 0.12 12.2 0.3 0.12 12.2 0.2 8.7 11 0 0 11 11 10 0 Zinc-finger domain RTC4 PF14474.1 EMC89098.1 - 0.13 12.2 0.2 38 4.2 0.0 3.6 3 1 1 4 4 4 0 RTC4-like domain Zn-ribbon_8 PF09723.5 EMC89098.1 - 0.22 11.4 68.5 2 8.4 2.5 10.7 4 2 6 10 10 10 0 Zinc ribbon domain RRN7 PF11781.3 EMC89098.1 - 0.28 10.7 52.7 1.2 8.6 0.1 10.6 12 0 0 12 12 12 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF164 PF02591.10 EMC89098.1 - 2.2 8.1 34.3 4.1 7.2 0.0 9.6 10 1 0 10 10 10 0 Putative zinc ribbon domain zf-HYPF PF07503.7 EMC89098.1 - 6 6.3 45.0 9.9 5.6 0.0 10.6 11 0 0 11 11 11 0 HypF finger Dopey_N PF04118.9 EMC89099.1 - 0.013 14.3 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal DUF2454 PF10521.4 EMC89099.1 - 0.018 14.0 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) Thiolase_N PF00108.18 EMC89100.1 - 2.5e-79 265.9 0.7 4.9e-78 261.7 0.5 2.1 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMC89100.1 - 1.8e-49 166.2 0.0 4e-49 165.1 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMC89100.1 - 1.2e-07 31.4 1.8 1.2e-07 31.4 1.2 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HEM4 PF02602.10 EMC89100.1 - 0.003 16.8 0.2 0.011 15.0 0.2 1.8 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD UIM PF02809.15 EMC89100.1 - 0.3 10.7 1.5 0.99 9.1 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif ACP_syn_III PF08545.5 EMC89100.1 - 0.49 10.0 5.5 2.3 7.9 0.2 3.3 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ECH PF00378.15 EMC89101.1 - 6.6e-80 267.7 0.2 1e-79 267.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 EMC89101.1 - 4.3e-57 192.6 1.2 8.2e-57 191.7 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMC89101.1 - 9.4e-26 90.0 0.2 2.8e-25 88.5 0.2 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain CABIT PF12736.2 EMC89102.1 - 2.2e-48 164.4 0.3 2.1e-32 112.1 0.1 3.1 2 1 1 3 3 3 3 Cell-cycle sustaining, positive selection, Cornifin PF02389.10 EMC89104.1 - 0.0012 18.6 12.7 0.0012 18.6 8.8 3.2 1 1 2 3 3 3 2 Cornifin (SPRR) family Pkinase PF00069.20 EMC89105.1 - 7.2e-36 123.6 0.2 8.2e-36 123.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89105.1 - 2.1e-18 66.3 0.1 2.4e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC89105.1 - 0.00016 20.8 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EMC89106.1 - 8.7e-27 93.8 0.0 1.1e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89106.1 - 2.7e-06 26.6 0.0 3.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC89107.1 - 1e-72 244.4 0.0 1.3e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89107.1 - 1.8e-30 105.8 0.1 2.8e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC89107.1 - 3.7e-05 22.8 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC89107.1 - 3.9e-05 23.5 0.3 0.00014 21.7 0.0 1.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC89107.1 - 0.00073 18.5 0.1 0.0037 16.2 0.0 2.1 2 1 1 3 3 3 1 Kinase-like DUF3754 PF12576.3 EMC89107.1 - 0.0027 17.3 0.1 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3754) Lipase_GDSL_2 PF13472.1 EMC89108.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AKNA PF12443.3 EMC89108.1 - 0.085 12.8 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor adh_short PF00106.20 EMC89109.1 - 1.1e-16 61.1 0.0 1.4e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EMC89109.1 - 0.00059 19.0 0.0 0.00079 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 EMC89109.1 - 0.0023 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC89109.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.0 1 0 0 1 1 1 0 KR domain RecA PF00154.16 EMC89109.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.3 1 1 0 1 1 1 0 recA bacterial DNA recombination protein GSG-1 PF07803.6 EMC89110.1 - 7.3e-43 144.9 0.2 1.3e-42 144.1 0.2 1.4 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 EMC89110.1 - 5.1e-12 45.8 5.6 7.3e-12 45.3 3.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EMC89110.1 - 2e-08 34.0 8.1 3.3e-08 33.3 5.5 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 EMC89110.1 - 0.0036 17.3 6.4 0.0094 15.9 4.4 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PepSY_TM PF03929.11 EMC89110.1 - 0.38 11.2 0.2 0.38 11.2 0.1 3.1 4 0 0 4 4 4 0 PepSY-associated TM helix CD20 PF04103.10 EMC89110.1 - 1.4 8.8 9.9 9.3 6.1 4.3 3.1 3 1 0 3 3 3 0 CD20-like family 7tm_2 PF00002.19 EMC89111.1 - 2e-79 266.0 17.6 2.5e-79 265.8 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC89111.1 - 4.1e-14 52.3 4.3 9.9e-14 51.1 3.0 1.7 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.7 EMC89111.1 - 0.00041 19.9 0.5 0.00074 19.1 0.0 1.7 2 0 0 2 2 2 1 SUR7/PalI family Hint_2 PF13403.1 EMC89112.1 - 0.019 14.9 3.7 1.5 8.7 0.4 3.3 1 1 2 3 3 3 0 Hint domain Toxin_58 PF15536.1 EMC89112.1 - 0.13 12.1 3.2 1.3 8.8 0.2 2.5 1 1 0 2 2 2 0 Putative toxin 58 Arm PF00514.18 EMC89113.1 - 7.2e-32 108.1 0.8 2.9e-09 36.4 0.0 7.1 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EMC89113.1 - 2.1e-09 36.8 1.8 0.00023 20.3 0.0 3.0 2 1 1 3 3 3 2 Armadillo-like HEAT_2 PF13646.1 EMC89113.1 - 6.9e-06 26.2 0.5 0.0091 16.2 0.0 3.0 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 EMC89113.1 - 0.027 14.5 0.3 9.6 6.5 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat Atx10homo_assoc PF09759.4 EMC89113.1 - 0.071 12.8 0.1 1.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 EMC89113.1 - 0.63 10.6 3.5 8.4 7.0 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat DUF4535 PF15054.1 EMC89115.1 - 2.9e-15 55.3 0.1 3.3e-15 55.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) Na_sulph_symp PF00939.14 EMC89116.1 - 7.8e-94 315.1 18.5 9.5e-94 314.9 12.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMC89116.1 - 1.5e-14 53.3 28.7 1.8e-06 26.7 7.9 3.1 2 1 1 3 3 3 3 Citrate transporter ArsB PF02040.10 EMC89116.1 - 3.2e-05 23.0 14.2 0.0065 15.4 2.6 2.6 3 0 0 3 3 3 2 Arsenical pump membrane protein SbmA_BacA PF05992.7 EMC89116.1 - 2.4 7.2 7.9 4.2 6.4 1.2 2.5 2 0 0 2 2 2 0 SbmA/BacA-like family FAM180 PF15173.1 EMC89117.1 - 5.1e-61 204.4 0.2 6.2e-61 204.1 0.2 1.1 1 0 0 1 1 1 1 FAM180 family Flag1_repress PF03614.8 EMC89117.1 - 0.13 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Pkinase PF00069.20 EMC89118.1 - 1.8e-58 197.7 0.0 2.3e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89118.1 - 1.3e-19 70.3 0.0 1.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC89118.1 - 3e-05 23.8 0.0 8.2e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC89118.1 - 0.0021 17.4 0.4 0.043 13.1 0.0 2.3 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMC89118.1 - 0.0029 16.9 0.0 0.0066 15.8 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EMC89118.1 - 0.0062 16.1 0.9 0.011 15.2 0.6 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EMC89118.1 - 0.0097 14.9 0.0 0.029 13.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like DUF2362 PF10154.4 EMC89121.1 - 6.3e-191 635.4 9.4 7.7e-191 635.1 6.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Noelin-1 PF12308.3 EMC89121.1 - 0.097 12.4 1.5 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF4412 PF14371.1 EMC89121.1 - 0.14 12.7 0.4 1.3 9.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4412) APG6 PF04111.7 EMC89121.1 - 3.1 6.7 11.7 0.15 11.0 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 FGF PF00167.13 EMC89122.1 - 1.6e-42 144.1 0.1 2.1e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Peptidase_C25_C PF03785.9 EMC89122.1 - 0.025 14.3 0.1 5.8 6.8 0.0 2.4 1 1 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain FGF PF00167.13 EMC89123.1 - 2.5e-20 72.4 0.0 3.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Cyclin_N PF00134.18 EMC89124.1 - 1.2e-35 121.8 1.4 1.2e-35 121.8 1.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC89124.1 - 4.8e-21 74.8 0.9 2.2e-20 72.7 0.0 2.3 3 1 0 3 3 3 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.5 EMC89124.1 - 0.033 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal 3Beta_HSD PF01073.14 EMC89125.1 - 2.1e-14 52.8 0.0 2.5e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC89125.1 - 1.6e-13 50.6 0.0 2.9e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMC89125.1 - 3.5e-13 49.9 0.0 5.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMC89125.1 - 2.6e-12 46.2 0.0 1.9e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EMC89125.1 - 1.6e-10 40.6 0.0 6.8e-10 38.6 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EMC89125.1 - 4.6e-05 22.4 0.2 0.11 11.3 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein Glycos_transf_2 PF00535.21 EMC89126.1 - 4.3e-22 78.5 0.2 6.6e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EMC89126.1 - 1.3e-10 41.3 0.0 2.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EMC89126.1 - 1.4e-05 25.0 0.0 5e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EMC89126.1 - 0.00025 20.4 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Lipase_GDSL_2 PF13472.1 EMC89127.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RasGEF_N_2 PF14663.1 EMC89127.1 - 0.098 12.6 0.2 0.28 11.1 0.1 1.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Avl9 PF09794.4 EMC89129.1 - 5.6e-11 41.5 0.1 3.7e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EMC89129.1 - 4.1e-10 39.3 0.0 8.6e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 EMC89129.1 - 4e-08 32.8 0.0 1e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.20 EMC89130.1 - 7.9e-62 208.7 0.0 1.2e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89130.1 - 7.2e-34 117.0 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EMC89130.1 - 4e-23 81.7 0.1 1.2e-22 80.1 0.1 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.1 EMC89130.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Arteri_nucleo PF01481.11 EMC89130.1 - 0.19 11.8 1.5 2.8 8.0 0.0 3.0 3 1 0 3 3 3 0 Arterivirus nucleocapsid protein RGS PF00615.14 EMC89132.1 - 1.5e-33 115.4 5.1 1.5e-33 115.4 3.5 1.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.6 EMC89132.1 - 0.00057 19.4 0.1 0.00074 19.0 0.0 1.4 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain RRM_1 PF00076.17 EMC89133.1 - 1.8e-59 197.2 0.1 2.1e-21 75.2 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89133.1 - 6.1e-32 109.4 0.2 2.3e-14 53.1 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89133.1 - 4.1e-31 106.6 0.4 1.2e-10 41.0 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC89133.1 - 7.7e-05 22.3 0.5 0.037 13.7 0.0 3.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EMC89133.1 - 8.4e-05 22.2 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 Calcipressin Nup35_RRM PF05172.8 EMC89133.1 - 0.00077 19.1 0.2 0.3 10.8 0.2 3.5 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMC89133.1 - 0.0061 16.3 0.0 4.5 7.1 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.6 EMC89133.1 - 0.078 12.9 0.1 4.4 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA binding domain HATPase_c PF02518.21 EMC89133.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Syja_N PF02383.13 EMC89135.1 - 3e-93 312.0 0.6 5e-93 311.3 0.4 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EMC89135.1 - 2.4e-32 110.6 0.1 1.9e-31 107.7 0.0 2.3 2 0 0 2 2 2 1 Inositol phosphatase MCM_bind PF09739.4 EMC89136.1 - 1.7e-41 140.5 0.1 2.9e-41 139.8 0.1 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 EMC89136.1 - 4.3e-36 123.2 1.5 8.8e-36 122.2 0.0 2.3 3 0 0 3 3 3 1 Putative alanine racemase RII_binding_1 PF10522.4 EMC89136.1 - 0.13 12.5 0.0 0.8 10.0 0.0 2.3 2 0 0 2 2 2 0 RII binding domain DDHD PF02862.12 EMC89137.1 - 1.5e-58 198.3 0.3 9.9e-57 192.3 0.0 2.3 2 0 0 2 2 2 1 DDHD domain SAM_1 PF00536.25 EMC89137.1 - 4.9e-13 49.0 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.15 EMC89137.1 - 8e-07 28.3 1.0 0.0037 16.6 0.1 2.6 1 1 1 2 2 2 2 WWE domain SAM_2 PF07647.12 EMC89137.1 - 5.2e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EMC89137.1 - 0.0043 16.9 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 IGR protein motif AIF_C PF14721.1 EMC89137.1 - 2.5 8.3 4.7 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TGF_beta PF00019.15 EMC89138.1 - 4.8e-38 129.6 0.6 8.7e-38 128.8 0.4 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC89138.1 - 1.9e-19 69.9 0.0 3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Ubiq_cyt_C_chap PF03981.7 EMC89139.1 - 4.6e-42 143.2 0.1 6.1e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Chlorophyllase PF07224.6 EMC89139.1 - 0.07 11.9 0.4 0.12 11.1 0.3 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF1669 PF07894.7 EMC89140.1 - 7.4e-62 209.1 0.5 7.4e-62 209.1 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1669) Actin PF00022.14 EMC89140.1 - 0.1 11.0 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Actin PLDc_2 PF13091.1 EMC89140.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain zf-CCCH_2 PF14608.1 EMC89141.1 - 0.00096 19.0 0.1 5.4 7.1 0.0 4.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Cornifin PF02389.10 EMC89141.1 - 5.3 6.7 29.5 4 7.1 15.6 2.6 1 1 1 2 2 2 0 Cornifin (SPRR) family eIF-6 PF01912.13 EMC89142.1 - 7.2e-40 136.2 0.1 5e-32 110.6 0.0 2.6 3 0 0 3 3 3 2 eIF-6 family Peptidase_M10 PF00413.19 EMC89143.1 - 6.1e-60 201.4 0.2 1.1e-59 200.6 0.2 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 EMC89143.1 - 1.9e-54 181.1 20.6 7.5e-16 57.5 0.6 4.5 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.3 EMC89143.1 - 2e-32 110.6 2.2 3.5e-32 109.8 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.13 EMC89143.1 - 6.3e-13 48.4 0.1 1.3e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 EMC89143.1 - 0.00015 21.2 0.8 0.45 9.8 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4293 PF14126.1 EMC89143.1 - 0.0066 16.3 0.1 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) Metallopep PF12044.3 EMC89143.1 - 0.055 11.9 0.1 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M54 PF07998.6 EMC89143.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_3 PF13582.1 EMC89143.1 - 0.097 13.1 0.7 0.21 12.1 0.5 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC89143.1 - 0.23 11.4 1.0 0.4 10.7 0.7 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ig_3 PF13927.1 EMC89144.1 - 0.0063 16.9 2.0 0.0074 16.7 0.5 1.8 2 1 0 2 2 2 1 Immunoglobulin domain SLAM PF06214.6 EMC89144.1 - 0.15 11.9 0.2 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein V-set PF07686.12 EMC89145.1 - 3.7e-07 30.0 0.0 7.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC89145.1 - 0.0061 16.6 1.2 1.6 8.8 0.7 2.8 1 1 1 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC89145.1 - 0.019 14.7 0.0 0.089 12.6 0.0 2.2 2 1 0 2 2 2 0 Immunoglobulin I-set domain ig PF00047.20 EMC89145.1 - 0.019 15.0 0.9 0.34 11.0 0.0 3.3 4 1 1 5 5 5 0 Immunoglobulin domain Strabismus PF06638.6 EMC89146.1 - 3.1e-252 837.3 3.3 7e-252 836.1 2.3 1.5 1 1 0 1 1 1 1 Strabismus protein MnhB PF04039.8 EMC89146.1 - 0.48 10.4 4.8 1 9.4 3.3 1.6 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter HLH PF00010.21 EMC89147.1 - 6.4e-19 67.3 0.3 6.4e-19 67.3 0.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RRXRR PF14239.1 EMC89147.1 - 0.064 12.6 1.6 0.086 12.2 1.1 1.3 1 0 0 1 1 1 0 RRXRR protein Nicastrin PF05450.10 EMC89148.1 - 9.6e-72 241.0 0.8 1.4e-71 240.4 0.6 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 EMC89148.1 - 3e-07 30.3 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 S_100 PF01023.14 EMC89149.1 - 2.8e-19 68.1 0.0 4.9e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 EMC89149.1 - 3.5e-08 32.1 1.5 1.5e-06 27.0 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMC89149.1 - 1.5e-07 31.3 0.1 1.9e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC89149.1 - 1.4e-05 24.5 0.4 0.014 15.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EMC89149.1 - 2.1e-05 23.6 2.3 0.00013 21.1 0.5 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC89149.1 - 6.5e-05 22.4 2.1 0.00095 18.7 1.5 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 EMC89149.1 - 0.024 14.3 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand S_100 PF01023.14 EMC89150.1 - 1.4e-07 30.7 0.0 2.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 EMC89150.1 - 0.0014 17.8 0.9 0.0023 17.0 0.6 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EMC89150.1 - 0.006 15.8 1.4 0.013 14.8 1.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.2 EMC89150.1 - 0.01 15.5 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 EMC89150.1 - 0.011 15.2 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair Enolase_N PF03952.11 EMC89150.1 - 0.018 14.9 3.1 18 5.2 0.1 3.5 2 1 1 3 3 3 0 Enolase, N-terminal domain EF-hand_7 PF13499.1 EMC89150.1 - 0.021 14.9 0.1 0.051 13.7 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EMC89150.1 - 0.054 13.4 0.6 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 EF-hand domain S_100 PF01023.14 EMC89151.1 - 0.0022 17.2 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain Potyvirid-P3 PF13608.1 EMC89152.1 - 4.1 6.3 10.8 17 4.3 3.9 2.1 1 1 1 2 2 2 0 Protein P3 of Potyviral polyprotein HC2 PF07382.6 EMC89155.1 - 0.00021 21.2 26.5 0.00021 21.2 18.4 2.5 1 1 1 2 2 2 1 Histone H1-like nucleoprotein HC2 GATase_5 PF13507.1 EMC89155.1 - 0.057 12.3 9.8 1 8.1 0.3 3.1 1 1 4 5 5 5 0 CobB/CobQ-like glutamine amidotransferase domain Keratin PF02422.11 EMC89157.1 - 2.4e-18 65.8 9.5 2.5e-18 65.8 6.6 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC89157.1 - 0.15 12.1 1.3 0.18 11.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) LELP1 PF15042.1 EMC89157.1 - 1.5 8.9 8.0 1.8 8.8 5.5 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 EMC89158.1 - 1.4e-19 69.8 10.1 1.6e-19 69.6 7.0 1.1 1 0 0 1 1 1 1 Keratin TIL PF01826.12 EMC89158.1 - 0.019 15.0 2.1 0.019 15.0 1.5 1.4 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 EMC89159.1 - 7.9e-19 67.4 12.9 8.8e-19 67.2 9.0 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.10 EMC89159.1 - 0.078 12.7 5.7 0.089 12.5 4.0 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3432 PF11914.3 EMC89159.1 - 0.13 12.2 3.6 0.23 11.4 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 EMC89160.1 - 7.9e-19 67.4 12.9 8.8e-19 67.2 9.0 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.10 EMC89160.1 - 0.078 12.7 5.7 0.089 12.5 4.0 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3432 PF11914.3 EMC89160.1 - 0.13 12.2 3.6 0.23 11.4 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 EMC89161.1 - 9e-22 76.8 8.4 1.4e-21 76.2 5.8 1.4 1 1 0 1 1 1 1 Keratin Cornifin PF02389.10 EMC89161.1 - 0.0098 15.6 5.5 0.0097 15.6 3.8 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family TMEM171 PF15471.1 EMC89161.1 - 0.019 13.7 0.6 0.019 13.7 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3432 PF11914.3 EMC89161.1 - 0.023 14.7 1.5 0.026 14.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) TIL PF01826.12 EMC89161.1 - 6 7.0 12.5 2.2 8.4 5.7 2.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 EMC89162.1 - 1.6e-20 72.8 4.7 1.6e-20 72.8 3.3 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC89162.1 - 0.43 10.6 5.1 0.52 10.3 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) LELP1 PF15042.1 EMC89162.1 - 6.5 6.9 9.4 7.6 6.7 6.5 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 EMC89163.1 - 6e-18 64.6 8.3 6.6e-18 64.4 5.8 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89164.1 - 3.7e-19 68.4 8.6 4.1e-19 68.3 6.0 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC89164.1 - 0.19 11.7 2.2 0.28 11.2 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 EMC89165.1 - 8.2e-30 102.6 9.9 9.7e-30 102.4 6.9 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89166.1 - 1.2e-30 105.3 10.3 1.4e-30 105.1 7.1 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89167.1 - 2.1e-28 98.1 4.5 2.2e-28 98.0 3.1 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89168.1 - 8.4e-31 105.8 7.2 9.3e-31 105.6 5.0 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89169.1 - 1.5e-30 105.0 10.6 1.7e-30 104.8 7.3 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89170.1 - 4.6e-39 132.3 15.3 8.5e-39 131.4 10.6 1.4 1 1 0 1 1 1 1 Keratin TIL PF01826.12 EMC89170.1 - 0.17 12.0 6.9 0.3 11.2 4.8 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 EMC89171.1 - 4.2e-46 154.9 9.6 4.4e-46 154.8 6.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89172.1 - 4.2e-47 158.0 10.7 4.6e-47 157.9 7.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 EMC89173.1 - 2.2e-46 155.7 10.7 2.4e-46 155.6 7.4 1.0 1 0 0 1 1 1 1 Keratin SERTA PF06031.8 EMC89174.1 - 4.9e-08 32.1 11.5 10 5.5 0.0 7.0 6 0 0 6 6 6 6 SERTA motif DUF1586 PF07625.6 EMC89174.1 - 0.00039 20.0 8.0 49 3.8 0.0 6.0 6 0 0 6 6 6 0 Protein of unknown function (DUF1586) NHL PF01436.16 EMC89174.1 - 0.0023 17.7 11.3 75 3.5 0.0 6.4 6 0 0 6 6 6 0 NHL repeat tRNA_int_end_N2 PF12928.2 EMC89174.1 - 0.053 12.9 5.0 2.2e+02 1.3 0.0 5.9 6 0 0 6 6 6 0 tRNA-splicing endonuclease subunit sen54 N-term TSP_1 PF00090.14 EMC89174.1 - 2.1 8.5 29.0 26 5.0 0.2 6.7 5 2 1 6 6 6 0 Thrombospondin type 1 domain DUF2685 PF10886.3 EMC89174.1 - 8.1 6.5 43.0 6.4 6.8 0.9 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF2685) COesterase PF00135.23 EMC89175.1 - 2.4e-79 267.4 0.0 2.6e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family 7tm_4 PF13853.1 EMC89176.1 - 9.9e-58 194.0 12.0 9.9e-58 194.0 8.3 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC89176.1 - 2.6e-31 108.6 21.2 4.5e-31 107.9 14.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CBFB_NFYA PF02045.10 EMC89177.1 - 2.8e-28 98.2 9.3 4.8e-28 97.4 6.4 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Packaging_FI PF14000.1 EMC89177.1 - 1.8 8.7 7.2 0.59 10.3 0.8 2.7 2 1 1 3 3 3 0 DNA packaging protein FI V-set PF07686.12 EMC89178.1 - 1.2e-09 38.0 0.4 2.3e-09 37.1 0.3 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain SIT PF15330.1 EMC89179.1 - 0.00036 20.6 0.1 0.00088 19.3 0.0 1.6 1 1 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.1 EMC89179.1 - 0.0048 16.6 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family V-set PF07686.12 EMC89180.1 - 5.5e-27 93.9 8.1 1.9e-14 53.4 1.0 2.0 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC89180.1 - 2.7e-07 30.5 5.9 0.00012 22.1 1.5 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC89180.1 - 1.2e-06 28.4 4.4 0.00074 19.5 0.5 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 EMC89180.1 - 2.6e-06 27.1 2.0 0.0056 16.4 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC89180.1 - 0.021 15.3 3.4 1.2 9.7 1.1 2.9 2 2 0 2 2 2 0 Immunoglobulin domain Histone PF00125.19 EMC89181.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89181.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EMC89181.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMC89181.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC89181.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMC89181.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC89181.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EMC89182.1 - 3.9e-33 113.4 0.4 6e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89182.1 - 0.00023 21.2 0.0 0.00035 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC89182.1 - 0.011 15.7 0.1 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EMC89182.1 - 0.014 14.6 0.5 0.022 14.0 0.4 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EMC89183.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89183.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC89183.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EMC89183.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EMC89184.1 - 5.8e-15 55.1 0.1 7e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89184.1 - 1.5e-05 25.0 0.1 2e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EMC89184.1 - 3.4e-05 23.7 0.2 4.6e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMC89184.1 - 0.00023 21.1 0.1 0.00037 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC89184.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMC89184.1 - 0.019 14.2 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC89184.1 - 0.04 13.6 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Linker_histone PF00538.14 EMC89185.1 - 1.6e-22 79.4 2.5 4.1e-22 78.0 1.7 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family Histone PF00125.19 EMC89186.1 - 4.1e-26 90.8 0.1 5.8e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC89186.1 - 1.2e-06 28.5 1.2 2.2e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC89186.1 - 0.0027 17.9 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 EMC89186.1 - 0.037 13.4 0.3 0.054 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 EMC89187.1 - 2.2e-27 94.9 0.0 2.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC89187.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC89188.1 - 5.9e-15 55.1 0.1 7.2e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89188.1 - 1.5e-05 25.0 0.1 2e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EMC89188.1 - 3.4e-05 23.6 0.2 4.7e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMC89188.1 - 0.00024 21.1 0.1 0.00038 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC89188.1 - 0.016 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMC89188.1 - 0.019 14.2 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC89188.1 - 0.041 13.6 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EMC89189.1 - 3.8e-26 90.9 0.1 5.3e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC89189.1 - 1.1e-06 28.5 1.1 2e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC89189.1 - 0.0025 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EMC89190.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89190.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC89190.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EMC89190.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EMC89191.1 - 4.3e-26 90.8 0.1 6e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC89191.1 - 1.2e-06 28.4 1.2 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC89191.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 EMC89191.1 - 0.059 12.8 0.2 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 EMC89192.1 - 4.1e-27 94.1 0.0 5.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC89192.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMC89193.1 - 2.6e-15 56.2 0.1 2.8e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89193.1 - 8.3e-06 25.9 0.1 1e-05 25.5 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EMC89193.1 - 1.9e-05 24.5 0.1 2.3e-05 24.2 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMC89193.1 - 0.00013 21.9 0.1 0.00018 21.4 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC89193.1 - 0.0087 15.7 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EMC89193.1 - 0.012 14.8 0.0 0.012 14.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC89193.1 - 0.023 14.4 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 EMC89193.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EMC89194.1 - 2e-19 69.4 0.3 1.4e-16 60.3 0.0 2.1 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89194.1 - 0.009 16.1 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EMC89195.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89195.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMC89195.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EMC89195.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EMC89196.1 - 4.2e-15 55.6 0.1 5e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMC89196.1 - 1.1e-05 25.4 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EMC89196.1 - 2.6e-05 24.0 0.2 3.5e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMC89196.1 - 0.00017 21.5 0.1 0.0003 20.7 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMC89196.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMC89196.1 - 0.014 14.6 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EMC89196.1 - 0.032 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EMC89197.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMC89197.1 - 9.5e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMC89197.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 EMC89197.1 - 0.038 13.4 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Linker_histone PF00538.14 EMC89198.1 - 5e-09 36.1 1.0 9.8e-09 35.1 0.7 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Wbp11 PF09429.5 EMC89199.1 - 9.1e-22 76.8 15.0 9.1e-22 76.8 10.4 3.3 3 1 0 3 3 3 1 WW domain binding protein 11 DUF4533 PF15047.1 EMC89200.1 - 1.4e-82 276.5 8.7 1.6e-82 276.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) BAR_3_WASP_bdg PF10456.4 EMC89200.1 - 0.022 14.0 0.7 0.037 13.2 0.3 1.5 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DNA_repr_REX1B PF14966.1 EMC89200.1 - 0.037 14.4 4.4 0.19 12.1 0.6 2.5 2 2 0 2 2 2 0 DNA repair REX1-B MobC PF05713.6 EMC89200.1 - 0.72 9.8 2.8 24 5.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) DUF4319 PF14203.1 EMC89200.1 - 0.84 9.2 3.8 1.8 8.1 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) ART PF01129.13 EMC89201.1 - 2.5e-51 173.9 1.8 2.9e-51 173.7 1.2 1.0 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.9 EMC89201.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 0 ADP-ribosyltransferase exoenzyme SGT1 PF07093.6 EMC89201.1 - 0.012 13.9 0.3 0.014 13.8 0.2 1.1 1 0 0 1 1 1 0 SGT1 protein Gla PF00594.15 EMC89202.1 - 1.1e-09 37.8 0.4 1.4e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain zf-C4_Topoisom PF01396.14 EMC89202.1 - 0.21 11.1 2.0 0.32 10.5 0.5 1.9 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Gla PF00594.15 EMC89203.1 - 2.7e-12 46.1 7.4 2.9e-12 46.0 3.2 2.0 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Thioredoxin_6 PF13848.1 EMC89205.1 - 1e-26 93.8 0.3 1.2e-26 93.6 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain Rho_GDI PF02115.12 EMC89206.1 - 4e-91 303.8 0.3 4.4e-91 303.7 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4316 PF14195.1 EMC89206.1 - 0.032 14.3 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) PDE6_gamma PF04868.7 EMC89207.1 - 3.6e-48 161.3 1.2 4e-48 161.1 0.8 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit TP1 PF02079.11 EMC89207.1 - 0.21 11.3 1.0 0.28 10.9 0.7 1.2 1 0 0 1 1 1 0 Nuclear transition protein 1 Peptidase_M14 PF00246.19 EMC89208.1 - 3.7e-30 105.4 0.0 6.1e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 EMC89208.1 - 0.0015 17.5 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TM140 PF14985.1 EMC89209.1 - 1.6e-22 80.0 0.2 1.8e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 TM140 protein family Yae1_N PF09811.4 EMC89210.1 - 2e-08 33.5 22.6 0.27 10.7 10.4 4.1 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Homeobox PF00046.24 EMC89211.1 - 1.7e-08 33.9 1.0 2e-08 33.6 0.7 1.1 1 0 0 1 1 1 1 Homeobox domain DNA_pol_B PF00136.16 EMC89212.1 - 7.1e-124 414.1 0.2 1.1e-123 413.4 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EMC89212.1 - 2.3e-58 196.6 6.9 4.3e-58 195.7 4.8 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EMC89212.1 - 2.9e-53 180.8 0.0 7.2e-53 179.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EMC89212.1 - 1.1e-15 57.1 14.1 1.1e-15 57.1 9.8 2.6 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.7 EMC89212.1 - 0.0091 14.6 0.5 0.041 12.4 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) CTP_transf_2 PF01467.21 EMC89213.1 - 1.2e-23 83.9 0.0 2.1e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase GldM_N PF12081.3 EMC89213.1 - 0.015 14.8 1.5 0.023 14.2 1.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Lipoprotein_6 PF01441.14 EMC89213.1 - 0.024 14.4 2.7 0.042 13.6 1.9 1.3 1 0 0 1 1 1 0 Lipoprotein UPF0158 PF03682.8 EMC89213.1 - 0.19 11.3 7.2 2.1 7.9 4.4 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0158) BCDHK_Adom3 PF10436.4 EMC89214.1 - 4.2e-53 179.2 0.0 6.3e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMC89214.1 - 3e-19 68.7 0.0 4.7e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMC89214.1 - 0.0064 16.1 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Solute_trans_a PF03619.11 EMC89215.1 - 1.6e-15 57.1 11.8 5.3e-15 55.4 8.2 1.6 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DUF2427 PF10348.4 EMC89215.1 - 0.092 12.3 9.4 0.23 11.0 0.7 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF2427) Zfx_Zfy_act PF04704.8 EMC89216.1 - 1.2e-161 537.1 22.4 1.2e-161 537.1 15.5 1.5 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-H2C2_2 PF13465.1 EMC89216.1 - 2.4e-46 153.8 117.8 2.8e-08 33.6 0.8 13.5 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89216.1 - 2.5e-40 134.3 115.9 1.4e-05 25.1 1.3 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89216.1 - 7e-30 101.1 98.6 0.00077 19.6 1.4 13.3 13 0 0 13 13 13 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89216.1 - 6.6e-17 61.1 71.0 0.0011 18.9 0.0 12.2 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC89216.1 - 4.1e-16 58.1 93.9 0.00044 20.3 1.0 12.3 12 0 0 12 12 12 8 C2H2-type zinc-finger domain ROS_MUCR PF05443.6 EMC89216.1 - 0.013 15.3 0.1 0.013 15.3 0.1 3.4 4 0 0 4 4 4 0 ROS/MUCR transcriptional regulator protein zf-C2H2_6 PF13912.1 EMC89216.1 - 0.039 13.8 0.7 0.039 13.8 0.5 10.5 11 0 0 11 11 11 0 C2H2-type zinc finger Adhes-Ig_like PF09085.5 EMC89216.1 - 0.14 12.0 1.2 0.37 10.6 0.8 1.7 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like zf-met PF12874.2 EMC89216.1 - 0.26 11.5 0.0 0.26 11.5 0.0 11.5 12 1 0 12 12 12 0 Zinc-finger of C2H2 type GTP_EFTU PF00009.22 EMC89217.1 - 8.3e-40 136.2 0.1 1.3e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EMC89217.1 - 1.2e-37 127.7 0.3 3e-37 126.5 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EMC89217.1 - 9.4e-13 48.0 0.3 2.7e-12 46.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMC89217.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC89217.1 - 0.079 12.7 0.2 0.54 10.0 0.1 2.1 1 1 0 2 2 2 0 Dynamin family Kelch_1 PF01344.20 EMC89218.1 - 6.2e-47 156.9 8.4 1.4e-12 46.9 0.0 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 EMC89218.1 - 2.1e-36 122.5 2.8 2.5e-10 40.0 0.0 5.7 3 2 2 5 5 5 5 Kelch motif BTB PF00651.26 EMC89218.1 - 4.4e-24 84.6 1.8 4.4e-24 84.6 1.2 2.2 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 EMC89218.1 - 2.1e-21 75.4 5.0 0.00064 19.4 0.0 6.2 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC89218.1 - 2.5e-19 68.9 0.3 6.4e-06 26.1 0.0 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.10 EMC89218.1 - 1.3e-16 60.3 0.7 2.7e-16 59.2 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 EMC89218.1 - 2e-14 52.7 11.4 0.00097 18.8 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EMC89218.1 - 2e-08 33.9 6.6 1.3 9.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Rax2 PF12768.2 EMC89218.1 - 0.00033 19.9 0.0 0.011 15.0 0.0 2.7 3 0 0 3 3 3 1 Cortical protein marker for cell polarity ApoO PF09769.4 EMC89219.1 - 3.5e-34 117.7 0.0 4.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein O Acetyltransf_1 PF00583.19 EMC89220.1 - 3.4e-16 59.0 0.0 5.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC89220.1 - 2.9e-08 33.7 0.2 8.2e-08 32.3 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC89220.1 - 4.7e-06 26.7 0.0 6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMC89220.1 - 0.00031 20.7 0.1 0.0022 17.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMC89220.1 - 0.00043 19.9 0.0 0.00099 18.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EMC89220.1 - 0.0019 18.3 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 4HBT PF03061.17 EMC89221.1 - 3.6e-10 39.8 0.0 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Patched PF02460.13 EMC89222.1 - 1.5e-98 330.7 22.5 2.7e-98 329.9 15.6 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EMC89222.1 - 1.9e-24 85.8 2.4 1.9e-24 85.8 1.7 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Peptidase_M13_N PF05649.8 EMC89223.1 - 4.3e-115 384.8 2.8 5.6e-115 384.4 1.9 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EMC89223.1 - 9.5e-57 191.4 0.2 1.9e-56 190.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 Spermine_synth PF01564.12 EMC89224.1 - 3.5e-61 206.2 0.1 4.3e-61 205.9 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Peptidase_M50 PF02163.17 EMC89225.1 - 1.8e-25 89.0 0.0 1e-24 86.5 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M50 PDZ_2 PF13180.1 EMC89225.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Chisel PF15355.1 EMC89226.1 - 2.6e-48 161.9 3.8 2.8e-48 161.8 2.7 1.0 1 0 0 1 1 1 1 Stretch-responsive small skeletal muscle X protein, Chisel Kelch_1 PF01344.20 EMC89227.1 - 2.3e-41 139.0 1.5 7.8e-11 41.3 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMC89227.1 - 2e-30 103.6 6.1 2.6e-07 30.5 0.0 6.3 3 3 3 6 6 6 5 Kelch motif BTB PF00651.26 EMC89227.1 - 4.9e-25 87.6 0.6 9.4e-25 86.7 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 EMC89227.1 - 7.9e-24 83.1 0.8 2.1e-05 24.1 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC89227.1 - 2.1e-23 81.8 0.2 0.0014 18.7 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC89227.1 - 5.7e-14 51.2 5.4 3.5e-06 26.5 0.0 5.4 5 2 0 5 5 5 3 Kelch motif BACK PF07707.10 EMC89227.1 - 2.5e-12 46.5 0.2 5.6e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 EMC89227.1 - 8.8e-10 38.3 5.9 0.29 11.1 0.0 5.5 6 0 0 6 6 6 3 Kelch motif DUF1170 PF06663.8 EMC89228.1 - 2.1e-80 269.1 5.2 2.1e-80 269.1 3.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 EMC89228.1 - 2.9e-36 123.3 5.0 1.7e-35 120.9 0.9 3.3 3 1 0 3 3 3 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.25 EMC89228.1 - 1e-14 54.4 2.9 1.9e-14 53.5 0.2 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PH PF00169.24 EMC89228.1 - 9.9e-14 51.4 6.2 1.9e-13 50.4 2.4 2.8 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 EMC89228.1 - 5.8e-10 38.8 0.6 3.8e-09 36.2 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 EMC89228.1 - 5.5e-09 36.0 0.1 1.6e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PH_9 PF15410.1 EMC89228.1 - 0.0015 18.6 4.7 0.095 12.8 2.0 3.6 4 1 0 4 4 4 1 Pleckstrin homology domain PDZ_2 PF13180.1 EMC89228.1 - 0.0056 16.5 0.1 0.036 13.9 0.0 2.3 2 0 0 2 2 2 1 PDZ domain ATG11 PF10377.4 EMC89228.1 - 0.037 13.9 0.5 0.089 12.6 0.3 1.6 1 0 0 1 1 1 0 Autophagy-related protein 11 PH_11 PF15413.1 EMC89228.1 - 0.071 13.3 11.0 0.057 13.6 4.7 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain eIF-1a PF01176.14 EMC89229.1 - 1.8e-27 94.5 0.2 2.3e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 MAP7 PF05672.6 EMC89230.1 - 1.2e-52 177.7 80.9 1.2e-52 177.7 56.1 3.2 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family THRAP3_BCLAF1 PF15440.1 EMC89231.1 - 2.2e-83 281.0 11.1 2.4e-83 280.9 7.7 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Gtr1_RagA PF04670.7 EMC89231.1 - 0.078 12.1 0.5 0.13 11.3 0.3 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Pentapeptide_2 PF01469.13 EMC89232.1 - 0.022 14.4 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Histone PF00125.19 EMC89233.1 - 7e-21 74.1 0.0 8.9e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Vps35 PF03635.12 EMC89235.1 - 0 1013.9 14.0 0 1013.7 9.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 ORC6 PF05460.8 EMC89236.1 - 2.5e-11 43.2 12.7 9.7e-10 38.0 0.7 2.9 2 1 1 3 3 3 2 Origin recognition complex subunit 6 (ORC6) HTH_36 PF13730.1 EMC89236.1 - 0.091 12.8 1.0 0.19 11.8 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain Synaptonemal_3 PF15191.1 EMC89236.1 - 0.54 10.0 4.0 0.93 9.2 0.9 2.7 2 2 0 2 2 2 0 Synaptonemal complex central element protein 3 Pkinase PF00069.20 EMC89237.1 - 1.7e-69 233.8 0.1 2.1e-69 233.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89237.1 - 3.2e-41 141.1 0.0 4.1e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC89237.1 - 0.00079 18.4 0.0 0.0013 17.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC89237.1 - 0.00086 18.4 0.2 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC89237.1 - 0.018 14.7 0.0 0.28 10.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMC89237.1 - 0.085 12.4 1.6 0.22 11.0 0.9 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase UPF0547 PF10571.4 EMC89238.1 - 0.00092 18.8 2.4 0.0015 18.2 1.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 GAGA_bind PF06217.7 EMC89238.1 - 0.12 12.3 3.8 0.13 12.1 2.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.5 EMC89238.1 - 0.19 11.7 7.2 0.21 11.6 5.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 G-7-MTase PF12803.2 EMC89238.1 - 0.23 10.5 2.3 0.77 8.8 1.0 1.8 1 1 1 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF1510 PF07423.6 EMC89238.1 - 0.46 9.8 7.4 0.55 9.5 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 EMC89238.1 - 1.6 8.5 6.0 1.7 8.4 4.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Transformer PF06495.6 EMC89238.1 - 3.1 7.6 16.9 4.1 7.2 11.7 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein NPR3 PF03666.8 EMC89238.1 - 5.6 5.3 8.6 6.4 5.1 6.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dsh_C PF12316.3 EMC89238.1 - 7 6.7 7.6 8.4 6.4 5.2 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.9 EMC89238.1 - 8.5 4.2 9.5 9.5 4.1 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein CTNNB1_binding PF08347.6 EMC89238.1 - 9.7 6.3 9.5 13 5.9 6.6 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding TPR_4 PF07721.9 EMC89239.1 - 3.5e-10 39.3 4.9 1.7e+02 3.1 0.0 10.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TSCPD PF12637.2 EMC89239.1 - 8.3e-05 22.4 7.5 2.8e+02 1.5 0.0 8.9 10 0 0 10 10 10 0 TSCPD domain Aminotran_1_2 PF00155.16 EMC89240.1 - 1.9e-30 106.0 0.0 2.2e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Borealin PF10512.4 EMC89241.1 - 3.2e-08 33.4 0.0 3.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 CTDII PF01556.13 EMC89242.1 - 5.5e-26 90.2 0.1 2.2e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain CUB PF00431.15 EMC89243.1 - 6.5e-42 142.0 0.3 4.3e-27 94.3 0.0 3.0 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.13 EMC89243.1 - 3.9e-06 26.6 4.7 3.9e-06 26.6 3.2 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Collagen PF01391.13 EMC89244.1 - 0.34 10.4 8.7 1.3 8.6 6.0 1.9 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Glyco_hydro_15 PF00723.16 EMC89245.1 - 2e-115 385.9 0.0 2.6e-115 385.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Lon_C PF05362.8 EMC89246.1 - 3e-79 265.0 0.0 4.9e-79 264.4 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EMC89246.1 - 8.7e-22 77.7 0.0 2.4e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EMC89246.1 - 3.1e-21 76.0 1.3 4.2e-21 75.5 0.1 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 EMC89246.1 - 1.2e-08 34.8 0.0 3e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EMC89246.1 - 9.9e-07 28.3 0.0 2.8e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EMC89246.1 - 2e-06 27.9 0.3 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 EMC89246.1 - 0.00025 20.6 0.0 0.00056 19.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMC89246.1 - 0.0011 19.7 0.0 0.004 17.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMC89246.1 - 0.0019 18.1 0.0 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 EMC89246.1 - 0.0029 16.3 0.0 0.027 13.1 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.1 EMC89246.1 - 0.0038 17.3 0.5 0.03 14.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMC89246.1 - 0.0064 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 TIP49 PF06068.8 EMC89246.1 - 0.0089 14.7 0.1 1.9 7.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus SKI PF01202.17 EMC89246.1 - 0.014 15.2 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.1 EMC89246.1 - 0.015 15.5 0.0 0.053 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EMC89246.1 - 0.023 13.7 0.0 0.077 12.0 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMC89246.1 - 0.024 14.5 0.7 0.063 13.1 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 EMC89246.1 - 0.038 13.5 2.1 0.15 11.5 0.3 2.4 2 1 1 3 3 3 0 AAA domain MobB PF03205.9 EMC89246.1 - 0.05 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EMC89246.1 - 0.086 12.7 0.1 0.96 9.3 0.0 2.6 2 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 EMC89246.1 - 0.12 11.7 0.3 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Birna_VP4 PF01768.11 EMC89246.1 - 0.15 11.1 0.1 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Birnavirus VP4 protein Sina PF03145.11 EMC89247.1 - 4e-81 271.4 0.2 6.3e-81 270.7 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family RNase_Zc3h12a PF11977.3 EMC89248.1 - 7.4e-57 191.5 0.0 1.5e-56 190.5 0.0 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF4392 PF14336.1 EMC89248.1 - 0.15 10.8 0.1 0.35 9.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4392) CCDC142 PF14923.1 EMC89249.1 - 0.066 11.5 0.0 0.089 11.1 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil protein 142 C1q PF00386.16 EMC89250.1 - 4e-08 33.3 0.0 4.2e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 C1q domain zf-C2H2 PF00096.21 EMC89251.1 - 1.5e-56 185.4 219.3 0.00022 21.3 0.8 30.7 31 0 0 31 31 31 26 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89251.1 - 1e-47 156.9 202.6 0.0049 17.1 0.4 30.5 31 0 0 31 31 31 21 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC89251.1 - 1.2e-40 135.8 196.8 4.8e-05 23.4 0.3 31.3 33 1 0 33 33 33 20 Zinc-finger double domain zf-Di19 PF05605.7 EMC89251.1 - 5.2e-24 84.1 186.4 8.8e-05 22.5 1.3 20.3 17 4 3 22 22 22 14 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMC89251.1 - 3.1e-21 74.5 165.8 2.2e-06 27.3 0.1 27.1 29 1 1 30 30 30 13 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89251.1 - 1.3e-19 69.7 162.8 0.001 19.1 0.8 26.2 26 2 2 28 28 28 14 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC89251.1 - 5.4e-06 26.4 172.4 0.3 11.1 3.3 24.6 7 5 12 21 21 21 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC89251.1 - 0.00089 19.3 8.0 0.0027 17.8 1.5 23.3 26 0 0 26 26 26 8 Zinc-finger of C2H2 type DUF4475 PF14753.1 EMC89252.1 - 0.012 15.1 2.8 0.013 15.0 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4475) Cys_rich_CWC PF14375.1 EMC89252.1 - 0.027 14.3 0.9 0.032 14.1 0.7 1.1 1 0 0 1 1 1 0 Cysteine-rich CWC Tmemb_18A PF09771.4 EMC89253.1 - 3.6e-59 198.2 0.4 3.9e-59 198.1 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 CopD PF05425.8 EMC89253.1 - 0.0036 17.4 0.1 0.0044 17.2 0.0 1.1 1 0 0 1 1 1 1 Copper resistance protein D DUF418 PF04235.7 EMC89253.1 - 0.047 13.3 0.3 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) HEAT_2 PF13646.1 EMC89254.1 - 1.2e-07 31.8 5.8 0.00057 20.1 0.0 4.1 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EMC89254.1 - 1.5e-05 24.6 10.8 0.1 12.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EMC89254.1 - 1.5e-05 25.2 5.2 0.00017 21.9 0.3 4.3 3 2 1 4 4 4 1 HEAT-like repeat Arm PF00514.18 EMC89254.1 - 0.0033 17.1 0.3 0.0033 17.1 0.2 5.9 7 1 1 8 8 8 1 Armadillo/beta-catenin-like repeat DUF1546 PF07571.8 EMC89254.1 - 0.047 13.8 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) PAP_assoc PF03828.14 EMC89255.1 - 1.5e-15 56.8 0.1 4.8e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMC89255.1 - 7.2e-15 55.0 0.1 1.8e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nitroreductase PF00881.19 EMC89256.1 - 0.00097 18.9 0.2 0.025 14.4 0.0 2.3 2 1 0 2 2 2 1 Nitroreductase family EF-hand_6 PF13405.1 EMC89256.1 - 0.0017 18.0 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EMC89256.1 - 0.014 15.5 0.2 0.059 13.5 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 EMC89256.1 - 0.016 14.4 0.0 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 EF hand Ribosomal_L23 PF00276.15 EMC89256.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L23 PX PF00787.19 EMC89257.1 - 1e-16 60.7 5.7 7.2e-16 57.9 2.7 2.8 3 0 0 3 3 3 1 PX domain TPR_12 PF13424.1 EMC89257.1 - 0.0016 18.3 0.0 0.0047 16.8 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat Ocnus PF05005.10 EMC89257.1 - 0.0023 17.7 0.1 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Janus/Ocnus family (Ocnus) MHC_I PF00129.13 EMC89257.1 - 0.051 12.9 0.2 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 TPR_11 PF13414.1 EMC89257.1 - 0.085 12.5 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 TPR repeat CAP_GLY PF01302.20 EMC89258.1 - 1.6e-41 139.8 1.0 2.3e-16 59.2 0.0 3.4 3 0 0 3 3 3 3 CAP-Gly domain UCH PF00443.24 EMC89258.1 - 2e-09 36.9 0.0 4.4e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COX_ARM PF06481.9 EMC89258.1 - 0.014 15.0 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 COX Aromatic Rich Motif HMG_box PF00505.14 EMC89259.1 - 6.3e-18 64.8 0.4 1.7e-17 63.4 0.2 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC89259.1 - 5.4e-12 45.9 0.7 5.4e-12 45.9 0.5 2.3 2 1 1 3 3 3 1 HMG-box domain PA-IL PF07828.7 EMC89259.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 PA-IL-like protein PMSI1 PF15322.1 EMC89259.1 - 0.34 9.9 23.4 0.15 11.1 1.5 2.5 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative UQ_con PF00179.21 EMC89260.1 - 2.7e-22 78.7 0.0 4.5e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3250 PF11618.3 EMC89261.1 - 3.4e-41 139.7 2.5 2.7e-35 120.7 0.8 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3250) C2 PF00168.25 EMC89261.1 - 7.3e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain FTO_NTD PF12933.2 EMC89262.1 - 7.3e-103 343.1 0.0 1.1e-102 342.5 0.0 1.2 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.2 EMC89262.1 - 5.8e-48 162.7 5.4 1.1e-47 161.7 3.7 1.5 1 0 0 1 1 1 1 FTO C-terminal domain Viral_protease PF08715.5 EMC89262.1 - 0.04 12.9 0.1 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 Papain like viral protease Homeobox_KN PF05920.6 EMC89263.1 - 5.1e-16 58.0 0.3 8.5e-16 57.3 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC89263.1 - 7.5e-09 35.0 0.4 9.1e-09 34.8 0.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC89263.1 - 0.0045 16.0 0.1 0.0092 15.0 0.0 1.6 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 EMC89263.1 - 0.016 15.2 0.1 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 Helicase associated domain MRP-S32 PF10210.4 EMC89263.1 - 0.05 13.9 1.1 0.06 13.6 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Homeobox_KN PF05920.6 EMC89265.1 - 6.1e-16 57.8 0.3 8.1e-16 57.4 0.2 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC89265.1 - 5.9e-09 35.4 0.8 7.2e-09 35.1 0.5 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC89265.1 - 0.0056 15.7 0.0 0.0089 15.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 EMC89265.1 - 0.0091 16.0 0.1 0.012 15.7 0.0 1.3 1 1 0 1 1 1 1 Helicase associated domain MRP-S32 PF10210.4 EMC89265.1 - 0.083 13.2 1.3 0.088 13.1 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Homeobox_KN PF05920.6 EMC89266.1 - 1.7e-16 59.6 0.2 2.8e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC89266.1 - 5.6e-09 35.4 1.9 6.8e-09 35.2 1.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC89266.1 - 0.0052 15.8 0.1 0.0092 15.0 0.0 1.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez MRP-S32 PF10210.4 EMC89266.1 - 0.13 12.6 2.0 0.14 12.5 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Phage_P2_GpE PF06528.7 EMC89266.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Phage P2 GpE Peptidase_M10 PF00413.19 EMC89267.1 - 1.2e-65 219.8 0.2 1.1e-64 216.7 0.1 2.2 1 1 0 1 1 1 1 Matrixin fn2 PF00040.14 EMC89267.1 - 4.8e-56 186.4 36.8 4.4e-19 68.1 2.5 3.7 3 0 0 3 3 3 3 Fibronectin type II domain Hemopexin PF00045.14 EMC89267.1 - 3e-41 138.8 8.9 3.5e-12 45.8 0.4 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 EMC89267.1 - 3.9e-09 36.3 0.0 9.1e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 EMC89267.1 - 0.0095 16.4 0.1 0.069 13.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EMC89267.1 - 0.012 15.0 0.0 4.7 6.5 0.0 2.6 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 EMC89267.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3152 PF11350.3 EMC89267.1 - 0.11 12.0 0.0 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Reprolysin_2 PF13574.1 EMC89267.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sulfotransfer_1 PF00685.22 EMC89268.1 - 1e-25 90.5 0.3 1.4e-25 90.0 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC89268.1 - 2.1e-06 28.7 0.1 5.9e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family PsbM PF05151.7 EMC89268.1 - 0.09 12.3 0.7 0.16 11.5 0.5 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) TM231 PF10149.4 EMC89269.1 - 1.5e-96 323.1 0.3 3.7e-96 321.8 0.2 1.5 1 1 0 1 1 1 1 Transmembrane protein 231 Atg8 PF02991.11 EMC89270.1 - 2e-50 169.0 0.1 2.3e-50 168.9 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMC89270.1 - 2.6e-06 27.5 0.0 3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_2 PF00152.15 EMC89271.1 - 7e-89 297.8 0.1 9.5e-89 297.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMC89271.1 - 5.3e-16 58.2 0.1 1.8e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC89271.1 - 7.6e-08 31.8 0.0 0.0049 16.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EMC89271.1 - 0.013 15.1 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Dec-1 PF04624.9 EMC89271.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Dec-1 repeat Rap1_C PF11626.3 EMC89272.1 - 1.9e-12 46.8 0.1 3.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Cep57_MT_bd PF06657.8 EMC89272.1 - 0.044 13.7 0.1 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sulfotransfer_1 PF00685.22 EMC89273.1 - 1.8e-26 93.0 0.0 2.6e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC89273.1 - 3.6e-06 27.9 0.0 1.3e-05 26.1 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Aminotran_1_2 PF00155.16 EMC89274.1 - 1.2e-74 251.4 0.0 1.4e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TAT_ubiq PF07706.7 EMC89274.1 - 2.6e-11 43.2 0.5 4.2e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase ubiquitination site Beta_elim_lyase PF01212.16 EMC89274.1 - 2.5e-07 30.1 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMC89274.1 - 1.4e-06 27.6 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EMC89274.1 - 3.4e-06 26.0 0.0 6.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMC89274.1 - 0.0042 15.4 0.0 0.0065 14.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 EMC89274.1 - 0.047 12.2 0.0 0.066 11.7 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MARVEL PF01284.18 EMC89275.1 - 4.3e-06 26.6 4.1 5.7e-06 26.2 2.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF1469 PF07332.6 EMC89275.1 - 0.00053 19.7 2.6 0.34 10.6 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1469) DUF3483 PF11982.3 EMC89275.1 - 0.067 12.4 0.5 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF3784 PF12650.2 EMC89275.1 - 0.093 12.6 1.2 0.26 11.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) LRR_8 PF13855.1 EMC89277.1 - 1.5e-44 149.5 67.9 1.6e-10 40.5 3.7 9.3 7 3 1 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 EMC89277.1 - 1.4e-43 145.8 69.9 9.5e-08 31.4 0.6 13.2 3 3 8 14 14 14 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC89277.1 - 2.4e-34 112.0 64.7 0.037 14.0 0.0 19.7 19 1 1 20 20 20 13 Leucine Rich Repeat PP2C PF00481.16 EMC89277.1 - 1.6e-28 99.7 0.0 2.7e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_7 PF13504.1 EMC89277.1 - 9.7e-13 46.0 73.6 0.45 10.9 0.1 19.2 20 0 0 20 20 20 7 Leucine rich repeat LRR_6 PF13516.1 EMC89277.1 - 2.5e-05 23.9 59.7 0.61 10.3 0.1 16.3 16 3 2 18 18 18 4 Leucine Rich repeat PH PF00169.24 EMC89277.1 - 0.0024 18.0 0.0 0.0067 16.6 0.0 1.7 1 0 0 1 1 1 1 PH domain AXH PF08517.7 EMC89278.1 - 1.4e-39 134.8 0.0 2.2e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) zf-met PF12874.2 EMC89280.1 - 4.8e-07 29.7 3.8 0.59 10.4 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMC89280.1 - 1e-05 25.5 0.2 0.37 11.1 0.0 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC89280.1 - 3.7e-05 23.7 10.9 0.1 13.0 0.6 3.8 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89280.1 - 0.00069 19.6 0.1 16 5.8 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMC89280.1 - 0.00071 19.6 1.6 0.00071 19.6 1.1 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EMC89280.1 - 0.0017 18.5 12.5 0.01 16.0 0.0 3.8 4 0 0 4 4 3 1 Zinc finger, C2H2 type CAF-1_p150 PF11600.3 EMC89280.1 - 0.0033 16.8 14.8 0.0033 16.8 10.3 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DZR PF12773.2 EMC89280.1 - 0.026 14.3 2.6 0.056 13.2 0.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.9 EMC89280.1 - 0.042 13.3 5.3 0.16 11.4 0.0 3.6 2 1 0 3 3 3 0 Rad50 zinc hook motif RRN7 PF11781.3 EMC89280.1 - 0.31 10.5 2.6 8.7 5.9 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 EMC89280.1 - 0.54 9.5 3.3 0.72 9.1 0.2 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-tcix PF14952.1 EMC89280.1 - 0.56 9.5 3.0 1.2 8.5 0.0 2.8 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding Peptidase_S46 PF10459.4 EMC89280.1 - 0.9 7.8 9.5 1.2 7.4 6.6 1.1 1 0 0 1 1 1 0 Peptidase S46 PhnA_Zn_Ribbon PF08274.7 EMC89280.1 - 3.4 7.5 12.9 12 5.7 0.1 3.8 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_4 PF14447.1 EMC89280.1 - 4.4 6.9 5.6 33 4.1 0.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Ist1 PF03398.9 EMC89281.1 - 1.9e-60 202.9 4.1 2.4e-60 202.7 2.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DHO_dh PF01180.16 EMC89282.1 - 1.2e-107 359.2 0.0 1.4e-107 359.1 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EMC89282.1 - 0.0026 16.6 0.2 0.011 14.6 0.2 2.0 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EMC89282.1 - 0.023 13.8 0.1 0.038 13.1 0.1 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase PcrB PF01884.12 EMC89282.1 - 0.035 13.3 0.0 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 PcrB family Trypsin PF00089.21 EMC89283.1 - 9.6e-47 159.3 0.0 1.1e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin BicD PF09730.4 EMC89284.1 - 0.00083 17.8 16.9 0.00094 17.6 11.7 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Myosin_tail_1 PF01576.14 EMC89284.1 - 0.0044 14.8 20.2 0.0049 14.6 14.0 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 EMC89284.1 - 0.0073 15.4 19.0 0.011 14.8 13.2 1.3 1 0 0 1 1 1 1 Tropomyosin BRE1 PF08647.6 EMC89284.1 - 0.039 13.9 18.3 0.051 13.5 10.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.4 EMC89284.1 - 0.052 13.4 23.5 0.066 13.0 16.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EMC89284.1 - 0.092 12.3 29.6 0.11 12.1 20.5 1.1 1 0 0 1 1 1 0 IncA protein DUF4201 PF13870.1 EMC89284.1 - 0.093 12.1 18.9 0.027 13.9 5.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 EMC89284.1 - 0.095 12.4 21.2 0.28 10.9 14.7 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Adap_comp_sub PF00928.16 EMC89284.1 - 0.097 11.7 0.4 0.1 11.6 0.3 1.1 1 0 0 1 1 1 0 Adaptor complexes medium subunit family WEMBL PF05701.6 EMC89284.1 - 0.14 10.6 22.4 0.22 9.9 15.5 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light CENP-Q PF13094.1 EMC89284.1 - 0.19 11.7 21.3 0.26 11.3 14.8 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 EMC89284.1 - 0.21 11.3 20.5 0.33 10.7 14.2 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Imm15 PF15590.1 EMC89284.1 - 0.26 10.4 4.1 0.19 10.8 0.3 2.1 1 1 1 2 2 2 0 Immunity protein 15 CALCOCO1 PF07888.6 EMC89284.1 - 0.29 9.3 15.2 0.33 9.1 10.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Thioesterase PF00975.15 EMC89284.1 - 0.29 11.3 4.8 0.33 11.1 3.3 1.1 1 0 0 1 1 1 0 Thioesterase domain DUF3086 PF11285.3 EMC89284.1 - 0.41 9.4 8.9 0.49 9.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) APG6 PF04111.7 EMC89284.1 - 0.42 9.6 23.2 0.52 9.3 16.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BBS2_C PF14782.1 EMC89284.1 - 0.44 9.0 9.0 0.54 8.7 6.3 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF3450 PF11932.3 EMC89284.1 - 0.48 9.6 19.2 0.57 9.3 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fez1 PF06818.10 EMC89284.1 - 0.53 10.2 23.4 0.081 12.9 9.3 2.0 1 1 1 2 2 2 0 Fez1 XPG_I_2 PF12813.2 EMC89284.1 - 0.54 9.6 7.1 0.59 9.5 4.9 1.2 1 0 0 1 1 1 0 XPG domain containing DNA_ligase_A_C PF04679.10 EMC89284.1 - 0.6 10.5 5.7 0.27 11.6 0.5 2.1 1 1 2 3 3 3 0 ATP dependent DNA ligase C terminal region TBPIP PF07106.8 EMC89284.1 - 0.72 9.3 15.8 0.45 10.0 9.8 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Macoilin PF09726.4 EMC89284.1 - 0.96 7.6 18.0 1.1 7.4 12.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 EMC89284.1 - 1.1 8.1 20.6 1.2 8.0 14.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CPSF100_C PF13299.1 EMC89284.1 - 1.2 9.2 7.9 1.6 8.9 5.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TetR_C_6 PF13977.1 EMC89284.1 - 1.6 8.7 7.9 7.9 6.5 5.3 1.9 1 1 1 2 2 2 0 Bacterial transcriptional repressor Rab5-bind PF09311.6 EMC89284.1 - 1.6 8.6 28.5 1.8 8.3 19.8 1.0 1 0 0 1 1 1 0 Rabaptin-like protein ERM PF00769.14 EMC89284.1 - 1.6 8.2 27.8 2.1 7.8 19.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FUSC PF04632.7 EMC89284.1 - 1.8 6.8 10.1 2 6.7 7.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Allexi_40kDa PF05549.6 EMC89284.1 - 2 7.6 6.0 2.8 7.1 3.9 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein DivIVA PF05103.8 EMC89284.1 - 2.1 8.4 20.1 7.4 6.6 12.7 2.1 1 1 1 2 2 2 0 DivIVA protein HAUS6_N PF14661.1 EMC89284.1 - 2.1 7.6 17.5 2.3 7.4 12.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 EMC89284.1 - 2.3 5.9 12.9 2.4 5.9 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 EMC89284.1 - 2.8 7.6 9.7 1.2 8.8 5.2 1.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Tho2 PF11262.3 EMC89284.1 - 2.9 6.8 8.4 3.4 6.6 5.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CENP-H PF05837.7 EMC89284.1 - 3 8.0 16.8 1.6 8.9 9.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.1 EMC89284.1 - 3.3 6.8 21.3 12 4.9 14.8 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Peptidase_S64 PF08192.6 EMC89284.1 - 3.6 5.8 9.4 3.7 5.7 6.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 TPR_MLP1_2 PF07926.7 EMC89284.1 - 3.9 7.2 28.1 5.8 6.6 19.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EMC89284.1 - 4.5 7.1 23.1 0.77 9.6 9.2 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding phage_tail_N PF08400.5 EMC89284.1 - 4.9 6.8 5.3 2.2 7.9 2.1 1.6 1 1 1 2 2 2 0 Prophage tail fibre N-terminal Fmp27_WPPW PF10359.4 EMC89284.1 - 6.1 5.1 15.3 0.63 8.3 3.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Rnk_N PF14760.1 EMC89284.1 - 6.2 6.9 8.4 6.1 7.0 0.1 3.3 3 0 0 3 3 3 0 Rnk N-terminus DUF4200 PF13863.1 EMC89284.1 - 6.6 6.6 24.0 70 3.3 16.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 EMC89284.1 - 6.9 5.2 18.2 2.9 6.4 9.0 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF972 PF06156.8 EMC89284.1 - 7.5 6.9 15.7 35 4.7 9.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) HR1 PF02185.11 EMC89284.1 - 8 6.2 24.7 0.51 10.1 1.0 3.7 1 1 2 3 3 3 0 Hr1 repeat Av_adeno_fibre PF06536.6 EMC89287.1 - 0.011 15.4 0.3 0.011 15.4 0.2 1.9 2 0 0 2 2 2 0 Avian adenovirus fibre MitMem_reg PF13012.1 EMC89289.1 - 4.8e-40 136.2 0.2 1.6e-39 134.5 0.3 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMC89289.1 - 5.9e-23 80.7 0.8 2.3e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNase_H2-Ydr279 PF09468.5 EMC89289.1 - 0.017 14.3 4.2 0.022 13.9 2.9 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) BSMAP PF12280.3 EMC89289.1 - 0.15 11.9 1.0 0.21 11.4 0.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein OAD_gamma PF04277.8 EMC89289.1 - 0.26 11.6 1.5 0.63 10.4 1.1 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain YqfQ PF14181.1 EMC89289.1 - 1.5 8.8 8.8 2.4 8.1 6.1 1.3 1 0 0 1 1 1 0 YqfQ-like protein Bap31 PF05529.7 EMC89289.1 - 3.9 6.8 7.3 6.1 6.2 5.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NOB1_Zn_bind PF08772.6 EMC89290.1 - 2.2e-30 104.3 0.1 3.4e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EMC89290.1 - 1.8e-06 27.7 3.1 2.9e-06 27.0 2.1 1.3 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Cys_rich_KTR PF14205.1 EMC89290.1 - 0.01 15.2 0.1 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR zf-ribbon_3 PF13248.1 EMC89290.1 - 0.021 14.0 0.3 0.046 12.9 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMC89290.1 - 0.034 13.6 0.4 0.075 12.5 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EMC89290.1 - 0.034 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_C31 PF05410.8 EMC89290.1 - 0.036 13.9 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha Zn-ribbon_8 PF09723.5 EMC89290.1 - 0.084 12.8 0.5 0.18 11.7 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 EMC89290.1 - 0.11 12.1 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EMC89290.1 - 0.19 11.8 0.2 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-RING_3 PF14369.1 EMC89290.1 - 0.67 10.0 2.9 1.7 8.6 2.0 1.6 1 0 0 1 1 1 0 zinc-finger RecR PF02132.10 EMC89290.1 - 2 7.9 4.0 43 3.6 1.9 2.9 2 1 0 2 2 2 0 RecR protein RHD PF00554.17 EMC89291.1 - 3.6e-21 75.6 0.2 2.5e-20 72.9 0.1 2.5 1 1 0 1 1 1 1 Rel homology domain (RHD) Cyt-b5 PF00173.23 EMC89292.1 - 2.1e-12 46.6 0.0 2.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EMP24_GP25L PF01105.19 EMC89293.1 - 1.7e-27 96.3 0.0 1.9e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dor1 PF04124.7 EMC89294.1 - 3.9e-98 328.0 1.2 4.9e-98 327.7 0.8 1.0 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 EMC89294.1 - 0.0012 18.6 1.7 0.0012 18.5 0.2 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec5 Utp13 PF08625.6 EMC89294.1 - 0.044 13.4 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain tRNA_m1G_MT PF01746.16 EMC89294.1 - 0.045 13.3 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase DUF1758 PF05585.7 EMC89294.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) DUF2450 PF10475.4 EMC89294.1 - 0.1 11.5 1.0 0.18 10.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Vps4_C PF09336.5 EMC89296.1 - 6.2e-26 90.0 0.4 1.4e-25 88.9 0.2 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA PF00004.24 EMC89296.1 - 8.5e-05 22.7 0.0 0.00032 20.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EMC89297.1 - 6.2e-31 107.3 0.0 1.2e-30 106.4 0.0 1.4 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMC89297.1 - 2.3e-07 30.9 0.2 5.6e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMC89297.1 - 3.8e-07 29.7 0.2 0.0066 15.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EMC89297.1 - 8.6e-07 28.5 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EMC89297.1 - 1.7e-06 26.9 0.0 2.3e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EMC89297.1 - 4.4e-06 26.7 0.1 0.001 19.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMC89297.1 - 6.9e-06 26.8 0.0 1.2e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMC89297.1 - 1.3e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC89297.1 - 1.6e-05 24.6 0.0 4.9e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMC89297.1 - 2.1e-05 23.7 0.0 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMC89297.1 - 6.2e-05 22.9 0.0 0.00016 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMC89297.1 - 9.6e-05 21.4 0.0 0.00013 20.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EMC89297.1 - 0.00014 21.7 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EMC89297.1 - 0.00035 20.2 0.0 0.086 12.4 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 EMC89297.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EMC89297.1 - 0.0022 17.1 0.2 0.9 8.6 0.0 2.2 1 1 1 2 2 2 2 KaiC RNA_helicase PF00910.17 EMC89297.1 - 0.0024 18.0 0.0 0.0042 17.2 0.0 1.5 1 1 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EMC89297.1 - 0.0026 16.8 0.0 0.0082 15.2 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 EMC89297.1 - 0.0035 17.0 0.0 0.23 11.1 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase PhoH PF02562.11 EMC89297.1 - 0.0037 16.5 0.1 0.0059 15.8 0.0 1.5 1 1 0 1 1 1 1 PhoH-like protein Sigma54_activ_2 PF14532.1 EMC89297.1 - 0.0041 17.1 0.0 0.0098 15.9 0.0 1.7 2 1 0 2 2 1 1 Sigma-54 interaction domain ResIII PF04851.10 EMC89297.1 - 0.0046 16.8 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Guanylate_kin PF00625.16 EMC89297.1 - 0.0064 15.9 0.0 0.062 12.7 0.0 2.1 1 1 0 2 2 2 1 Guanylate kinase Mg_chelatase PF01078.16 EMC89297.1 - 0.0065 15.6 0.2 0.015 14.4 0.0 1.6 2 1 0 2 2 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EMC89297.1 - 0.0092 15.4 0.0 0.049 13.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 EMC89297.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain EF-1_beta_acid PF10587.4 EMC89297.1 - 0.015 15.4 0.8 0.43 10.7 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region AAA_28 PF13521.1 EMC89297.1 - 0.03 14.2 0.0 0.052 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 EMC89297.1 - 0.03 13.1 0.0 0.051 12.3 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family KAP_NTPase PF07693.9 EMC89297.1 - 0.033 13.1 0.1 0.22 10.5 0.1 2.0 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 EMC89297.1 - 0.045 13.3 0.1 0.073 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMC89297.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EMC89297.1 - 0.06 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 EMC89297.1 - 0.065 12.6 0.1 0.51 9.7 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_21 PF13304.1 EMC89297.1 - 0.066 13.1 0.3 2.5 7.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMC89297.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter KTI12 PF08433.5 EMC89297.1 - 0.094 11.9 0.1 0.23 10.6 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EMC89297.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EMC89297.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.11 EMC89297.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase NTPase_1 PF03266.10 EMC89297.1 - 0.12 12.0 0.0 3.8 7.1 0.0 2.1 2 0 0 2 2 2 0 NTPase Zot PF05707.7 EMC89297.1 - 0.12 11.7 0.3 1.4 8.3 0.2 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 EMC89297.1 - 0.13 11.2 0.0 0.29 10.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 EMC89297.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin WD40 PF00400.27 EMC89298.1 - 1.1e-08 34.6 17.1 0.0014 18.4 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Ctf8 PF09696.5 EMC89299.1 - 2.2e-19 69.3 0.1 3.9e-19 68.6 0.1 1.4 1 1 0 1 1 1 1 Ctf8 Glycos_transf_2 PF00535.21 EMC89300.1 - 1.3e-09 37.9 0.0 0.00067 19.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMC89300.1 - 5.9e-09 36.0 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 EMC89300.1 - 0.00025 19.5 0.0 0.3 9.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMC89300.1 - 0.0024 17.5 0.4 0.0024 17.5 0.3 3.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 CD52 PF15116.1 EMC89300.1 - 0.22 11.3 1.2 0.44 10.3 0.8 1.5 1 0 0 1 1 1 0 CAMPATH-1 antigen DUF2435 PF10363.4 EMC89301.1 - 8.4e-20 70.4 0.5 4.2e-19 68.2 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EMC89301.1 - 2.2e-09 36.6 1.4 5.2e-09 35.3 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT_2 PF13646.1 EMC89301.1 - 6.8e-05 23.0 5.2 0.17 12.1 0.2 3.4 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EMC89301.1 - 0.00012 22.4 0.1 0.00012 22.4 0.1 5.3 5 1 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 EMC89301.1 - 0.00025 20.8 3.5 7.1 7.0 0.1 6.1 4 1 1 5 5 5 2 HEAT repeat Cadherin PF00028.12 EMC89302.1 - 4.8e-73 241.4 4.6 1.5e-21 76.4 0.2 4.1 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.7 EMC89302.1 - 0.0024 17.4 0.0 14 5.3 0.0 3.6 3 0 0 3 3 3 3 Cadherin-like Transthyretin PF00576.16 EMC89303.1 - 5.9e-39 132.4 0.0 6.6e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family GAS PF13851.1 EMC89304.1 - 1.3e-66 223.6 31.6 1.3e-66 223.6 21.9 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Metal_resist PF13801.1 EMC89304.1 - 0.08 12.9 2.8 0.25 11.3 0.0 2.8 1 1 3 4 4 4 0 Heavy-metal resistance Virulence_fact PF13769.1 EMC89304.1 - 0.27 11.1 5.0 0.29 11.0 0.1 3.1 3 0 0 3 3 3 0 Virulence factor DUF948 PF06103.6 EMC89304.1 - 0.4 10.5 0.1 0.4 10.5 0.1 3.8 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4303 PF14136.1 EMC89304.1 - 0.71 9.5 6.8 0.85 9.2 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4303) Baculo_PEP_C PF04513.7 EMC89304.1 - 1.5 8.6 15.4 1.9 8.3 2.1 3.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.13 EMC89304.1 - 2.6 7.7 12.3 0.82 9.4 4.1 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Reo_sigmaC PF04582.7 EMC89304.1 - 3.4 6.7 6.0 11 5.1 0.1 2.8 1 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF4515 PF14988.1 EMC89304.1 - 5.4 6.6 44.6 4.1 7.0 1.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4515) Peptidase_U57 PF05582.7 EMC89304.1 - 8 5.3 9.4 8.3 5.2 5.8 1.6 1 1 0 1 1 1 0 YabG peptidase U57 Dysbindin PF04440.11 EMC89305.1 - 2.2e-36 124.8 0.3 2.4e-36 124.6 0.2 1.0 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) DUF4206 PF13901.1 EMC89306.1 - 2e-63 213.6 7.9 2e-63 213.6 5.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4206) C1_1 PF00130.17 EMC89306.1 - 3.3e-07 29.9 30.0 1.4e-06 27.9 5.8 4.2 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DYW_deaminase PF14432.1 EMC89306.1 - 0.2 11.6 4.9 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases Tubulin PF00091.20 EMC89307.1 - 2.6e-54 184.2 0.0 4.4e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC89307.1 - 2e-49 166.7 0.1 4e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain 7tm_1 PF00001.16 EMC89307.1 - 9.2e-39 133.1 35.9 7.1e-37 126.9 24.9 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC89307.1 - 9e-05 21.7 33.8 0.00027 20.2 23.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Tubulin_3 PF14881.1 EMC89307.1 - 0.039 13.4 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain DUF809 PF05663.6 EMC89307.1 - 0.046 13.6 1.0 0.13 12.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Tcf25 PF04910.9 EMC89308.1 - 4.5e-108 361.4 7.7 5.7e-108 361.0 5.3 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SPT6_acidic PF14632.1 EMC89308.1 - 0.11 12.6 3.3 0.3 11.2 2.3 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 zf-C2H2_4 PF13894.1 EMC89309.1 - 1.3e-14 53.3 37.0 0.0025 18.0 0.8 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC89309.1 - 2.8e-14 52.4 42.2 0.00011 22.3 1.6 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC89309.1 - 1.1e-11 44.4 44.2 0.00019 21.5 0.1 7.1 7 0 0 7 7 7 4 Zinc-finger double domain zf-AD PF07776.10 EMC89309.1 - 0.0019 18.1 0.2 0.0019 18.1 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger associated domain (zf-AD) Zn-ribbon_8 PF09723.5 EMC89309.1 - 0.14 12.1 22.6 0.21 11.5 0.0 4.7 4 1 0 4 4 4 0 Zinc ribbon domain IBR PF01485.16 EMC89309.1 - 0.26 11.1 23.3 3.9 7.4 0.3 5.0 2 1 1 3 3 3 0 IBR domain ADK_lid PF05191.9 EMC89309.1 - 0.47 10.1 13.2 0.45 10.2 0.1 4.5 5 0 0 5 5 5 0 Adenylate kinase, active site lid DUF2197 PF09963.4 EMC89309.1 - 0.61 10.0 8.7 0.43 10.5 0.4 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_6 PF13912.1 EMC89309.1 - 2.3 8.2 20.6 1.8 8.5 0.4 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger Pkinase PF00069.20 EMC89311.1 - 7.4e-65 218.6 0.0 8.8e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89311.1 - 1.7e-33 115.7 0.0 2.4e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC89311.1 - 7e-09 35.0 0.1 3.7e-07 29.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EMC89311.1 - 0.0021 17.4 0.3 0.0035 16.6 0.2 1.3 1 1 0 1 1 1 1 RIO1 family Herpes_IE1 PF07340.6 EMC89311.1 - 0.0042 15.5 0.2 0.0056 15.1 0.1 1.1 1 0 0 1 1 1 1 Cytomegalovirus IE1 protein DUF244 PF03112.9 EMC89311.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF APH PF01636.18 EMC89311.1 - 0.076 12.7 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M19 PF01244.16 EMC89312.1 - 1.3e-45 155.7 1.0 1.4e-45 155.6 0.7 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Sulfotransfer_1 PF00685.22 EMC89313.1 - 4.3e-10 39.2 0.1 7.1e-10 38.5 0.1 1.2 1 1 0 1 1 1 1 Sulfotransferase domain Copine PF07002.11 EMC89314.1 - 4.9e-62 207.9 0.0 7.6e-62 207.3 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EMC89314.1 - 1.7e-07 31.3 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EMC89314.1 - 0.0076 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Peptidase_M41 PF01434.13 EMC89315.1 - 5.5e-71 238.4 0.3 8.7e-71 237.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMC89315.1 - 3.6e-39 133.9 0.0 1e-38 132.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EMC89315.1 - 1.7e-07 31.3 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EMC89315.1 - 9.8e-07 28.5 0.3 1.7e-05 24.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMC89315.1 - 0.00014 22.0 0.1 0.052 13.6 0.0 3.5 2 1 2 4 4 4 1 AAA domain AAA_2 PF07724.9 EMC89315.1 - 0.00015 21.7 0.0 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMC89315.1 - 0.00017 21.6 0.3 0.0033 17.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EMC89315.1 - 0.0012 17.9 0.0 0.0031 16.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMC89315.1 - 0.0028 18.4 0.0 0.013 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMC89315.1 - 0.0028 16.4 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EMC89315.1 - 0.0067 16.1 0.3 0.028 14.1 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 EMC89315.1 - 0.0077 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMC89315.1 - 0.015 14.4 0.1 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMC89315.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMC89315.1 - 0.028 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMC89315.1 - 0.068 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMC89315.1 - 0.084 11.9 0.1 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NAD_binding_1 PF00175.16 EMC89315.1 - 0.091 13.3 0.0 0.86 10.1 0.0 2.5 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain NACHT PF05729.7 EMC89315.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Peptidase_M50B PF13398.1 EMC89315.1 - 0.31 10.3 0.1 0.31 10.3 0.0 2.1 3 0 0 3 3 3 0 Peptidase M50B-like Ank_2 PF12796.2 EMC89316.1 - 1.5e-23 82.9 0.3 3.9e-13 49.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC89316.1 - 2.2e-23 80.8 0.2 9.8e-07 28.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMC89316.1 - 5.5e-20 71.3 3.6 3e-09 37.1 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC89316.1 - 4.8e-19 67.9 0.4 4.3e-09 36.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89316.1 - 3e-13 48.5 0.2 0.00085 19.3 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat AMP-binding PF00501.23 EMC89317.1 - 1.7e-82 277.0 0.1 2.7e-82 276.4 0.1 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC89317.1 - 2e-14 54.2 0.1 5.6e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.17 EMC89318.1 - 6.7e-17 60.8 0.0 9.8e-17 60.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89318.1 - 3.1e-14 52.6 0.0 4.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89318.1 - 4.6e-08 32.8 0.0 7.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Shugoshin_N PF07558.6 EMC89318.1 - 0.11 12.1 0.5 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Nup35_RRM_2 PF14605.1 EMC89318.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sedlin_N PF04628.8 EMC89319.1 - 1.5e-36 125.1 0.6 1.7e-36 125.0 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EMC89319.1 - 2.5e-10 40.2 0.2 3e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family Sulfatase PF00884.18 EMC89320.1 - 2.2e-81 273.3 0.0 3e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMC89320.1 - 2.9e-36 124.6 0.0 4.8e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EMC89320.1 - 3e-10 39.9 0.0 6.4e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMC89320.1 - 0.015 13.7 0.0 0.018 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Pribosyltran PF00156.22 EMC89321.1 - 5.9e-23 80.9 0.0 6.7e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMC89321.1 - 6.9e-05 22.1 0.0 9.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EMC89321.1 - 0.065 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CDT1 PF08839.6 EMC89322.1 - 1.7e-52 177.6 0.4 5.9e-52 175.8 0.2 1.9 3 0 0 3 3 3 1 DNA replication factor CDT1 like DUF3595 PF12166.3 EMC89323.1 - 1.6e-68 231.4 0.1 2.3e-68 230.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) PBP1_TM PF14812.1 EMC89323.1 - 0.0071 16.6 2.3 0.016 15.5 0.4 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Di19 PF05605.7 EMC89324.1 - 2.6e-18 65.8 14.5 1.3e-17 63.6 2.3 2.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Rubredoxin PF00301.15 EMC89324.1 - 0.00044 20.0 2.9 2.8 7.9 0.0 3.5 3 0 0 3 3 3 1 Rubredoxin UIM PF02809.15 EMC89324.1 - 0.0024 17.2 3.8 0.0043 16.5 2.7 1.4 1 0 0 1 1 1 1 Ubiquitin interaction motif PhnA_Zn_Ribbon PF08274.7 EMC89324.1 - 0.0067 16.1 0.1 3.6 7.4 0.0 3.8 3 1 0 3 3 3 1 PhnA Zinc-Ribbon DUF4187 PF13821.1 EMC89324.1 - 0.09 12.3 0.2 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zinc_ribbon_2 PF13240.1 EMC89324.1 - 0.11 12.0 0.1 0.11 12.0 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-BED PF02892.10 EMC89324.1 - 0.21 11.3 8.2 0.51 10.1 0.3 3.4 3 1 0 3 3 3 0 BED zinc finger zf-ribbon_3 PF13248.1 EMC89324.1 - 0.29 10.3 0.0 0.29 10.3 0.0 4.4 5 0 0 5 5 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 EMC89324.1 - 0.41 11.1 15.4 1.5 9.3 0.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Cmc1 PF08583.5 EMC89324.1 - 0.88 9.3 5.3 12 5.7 0.5 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-H2C2_2 PF13465.1 EMC89324.1 - 1 9.7 14.4 2.7 8.4 0.5 4.6 4 0 0 4 4 4 0 Zinc-finger double domain Prok-RING_1 PF14446.1 EMC89324.1 - 1.8 8.3 14.3 7.1 6.4 0.6 4.4 3 2 1 4 4 4 0 Prokaryotic RING finger family 1 zf-C4pol PF14260.1 EMC89324.1 - 3.1 7.8 13.5 0.86 9.6 3.4 2.8 2 2 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Prok-RING_4 PF14447.1 EMC89324.1 - 3.8 7.1 7.4 4 7.0 0.3 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EMC89324.1 - 4.3 6.8 10.3 1.1 8.8 3.7 2.5 2 0 0 2 2 2 0 P-11 zinc finger DZR PF12773.2 EMC89324.1 - 4.9 7.0 22.5 1.5e+04 -6.1 15.6 3.6 1 1 0 1 1 0 0 Double zinc ribbon Elf1 PF05129.8 EMC89324.1 - 7.8 6.2 8.5 1.1 9.0 0.4 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF4451 PF14616.1 EMC89324.1 - 9 6.0 11.0 1.9 8.2 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) GHMP_kinases_N PF00288.21 EMC89325.1 - 0.00029 20.8 0.2 0.00055 19.9 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Sulfotransfer_3 PF13469.1 EMC89325.1 - 0.057 14.3 0.1 0.09 13.7 0.1 1.3 1 1 0 1 1 1 0 Sulfotransferase family Cytochrom_B558a PF05038.8 EMC89326.1 - 4.6e-48 163.3 6.0 5.1e-41 140.3 0.8 2.0 2 0 0 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit IL17 PF06083.6 EMC89327.1 - 8.1e-32 109.1 0.5 1.2e-31 108.6 0.4 1.2 1 0 0 1 1 1 1 Interleukin-17 CIDE-N PF02017.10 EMC89328.1 - 4.5e-13 48.7 0.1 7.5e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 CIDE-N domain GlyL_C PF12524.3 EMC89328.1 - 0.22 11.4 1.0 2 8.4 0.3 2.7 2 1 0 2 2 2 0 dsDNA virus glycoprotein L C terminal zf-C2H2_4 PF13894.1 EMC89329.1 - 1.7e-09 37.3 20.3 0.041 14.2 0.9 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC89329.1 - 6.1e-09 35.6 22.6 0.00097 19.3 0.9 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC89329.1 - 3.6e-06 26.9 0.0 3.6e-06 26.9 0.0 4.8 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC89329.1 - 1e-05 25.5 4.8 0.041 14.0 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC89329.1 - 2.5e-05 24.2 10.7 0.029 14.5 0.7 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC89329.1 - 9.3e-05 22.1 4.4 0.00066 19.4 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger GAGA PF09237.6 EMC89329.1 - 0.099 12.2 2.5 0.68 9.5 0.7 2.4 2 0 0 2 2 2 0 GAGA factor TF_Zn_Ribbon PF08271.7 EMC89329.1 - 5.3 6.4 7.5 5.9 6.3 1.5 3.5 4 1 0 4 4 4 0 TFIIB zinc-binding zf-C2H2 PF00096.21 EMC89330.1 - 6.9e-08 32.3 22.6 0.0044 17.2 2.1 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89330.1 - 1.6e-05 24.9 25.4 0.0016 18.6 0.5 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC89330.1 - 0.0017 18.3 9.9 0.0017 18.3 6.9 2.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EMC89330.1 - 0.0021 18.1 21.1 0.11 12.8 1.6 3.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-met PF12874.2 EMC89330.1 - 0.033 14.4 1.6 0.033 14.4 1.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-FCS PF06467.9 EMC89330.1 - 0.76 9.4 6.3 2.1 8.0 0.1 3.1 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EMC89330.1 - 4.1 7.8 25.2 1 9.7 1.5 5.6 4 1 0 4 4 4 0 Zinc-finger double domain DZR PF12773.2 EMC89330.1 - 5.8 6.8 7.9 5.8 6.8 1.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon BEN PF10523.4 EMC89331.1 - 3.5e-10 39.7 0.1 6.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 BEN domain Tbf5 PF06331.7 EMC89331.1 - 0.027 14.2 0.5 0.06 13.1 0.3 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Carb_anhydrase PF00194.16 EMC89332.1 - 2.3e-107 357.7 0.0 2.8e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AA_permease_2 PF13520.1 EMC89333.1 - 7.6e-64 215.8 43.0 9.1e-64 215.5 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC89333.1 - 1e-25 90.0 39.2 1.5e-25 89.5 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease Kelch_3 PF13415.1 EMC89334.1 - 9e-40 133.9 5.6 4.5e-10 39.4 0.0 7.7 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC89334.1 - 2.1e-38 129.8 3.6 1.9e-09 37.1 0.0 6.9 6 3 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EMC89334.1 - 1e-28 98.2 6.0 2e-06 27.7 0.0 6.4 5 2 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMC89334.1 - 8.1e-26 89.5 6.8 3.6e-06 26.8 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EMC89334.1 - 3e-18 64.7 16.3 4.3e-05 23.1 0.0 8.0 6 3 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EMC89334.1 - 8.4e-17 60.4 11.0 2.2e-06 27.1 0.0 7.6 6 2 0 6 6 6 4 Kelch motif DUF4110 PF13422.1 EMC89334.1 - 0.00015 21.5 0.2 0.00015 21.5 0.1 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4110) Hom_end_hint PF05203.11 EMC89334.1 - 0.033 13.9 1.6 5.6 6.6 0.0 3.0 2 2 1 3 3 3 0 Hom_end-associated Hint Atg8 PF02991.11 EMC89335.1 - 8.7e-44 147.7 0.2 9.8e-44 147.5 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMC89335.1 - 1.5e-06 28.2 0.0 1.9e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2407 PF10302.4 EMC89335.1 - 0.032 14.4 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 EMC89335.1 - 0.066 12.9 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing SBF2 PF12335.3 EMC89336.1 - 1.6e-05 24.3 1.1 0.00011 21.6 0.2 2.3 2 0 0 2 2 2 1 Myotubularin protein ARA70 PF12489.3 EMC89336.1 - 0.17 11.8 5.2 0.22 11.4 0.6 2.5 2 0 0 2 2 2 0 Nuclear coactivator COX4 PF02936.9 EMC89337.1 - 5.8e-44 149.2 0.3 6.7e-44 149.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PepSY_TM_1 PF13172.1 EMC89337.1 - 0.077 12.7 1.0 0.12 12.1 0.7 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DSPc PF00782.15 EMC89338.1 - 1.2e-29 102.5 0.0 1.4e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMC89338.1 - 3.9e-05 23.1 0.0 4.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMC89338.1 - 0.00041 20.4 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate IRF-3 PF10401.4 EMC89339.1 - 4.6e-61 205.5 0.2 6.6e-61 205.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 EMC89339.1 - 4.9e-47 158.2 0.7 8.9e-47 157.4 0.5 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.9 EMC89339.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 MH2 domain Fork_head PF00250.13 EMC89340.1 - 3.1e-26 91.2 0.0 1.4e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 Fork head domain Fork_head PF00250.13 EMC89341.1 - 3.7e-46 155.0 0.1 6.1e-46 154.3 0.1 1.3 1 0 0 1 1 1 1 Fork head domain Fork_head PF00250.13 EMC89342.1 - 2.2e-43 146.1 0.0 2.4e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Fork head domain zf-DHHC PF01529.15 EMC89344.1 - 7.5e-39 132.9 9.3 7.5e-39 132.9 6.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Hormone_recep PF00104.25 EMC89345.1 - 9.9e-39 132.5 0.0 1.4e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC89345.1 - 5.5e-30 103.4 17.9 8.9e-30 102.7 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 EMC89345.1 - 0.098 10.1 2.0 0.12 9.8 1.4 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein LCCL PF03815.14 EMC89346.1 - 1.6e-49 165.8 12.9 1.9e-26 91.8 0.3 3.1 3 0 0 3 3 3 2 LCCL domain CAP PF00188.21 EMC89346.1 - 1.9e-19 70.3 6.1 4.1e-19 69.2 4.2 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.5 EMC89346.1 - 0.00012 22.2 0.0 0.09 13.0 0.1 3.0 2 1 0 2 2 2 2 Histone deacetylation protein Rxt3 UCH PF00443.24 EMC89347.1 - 6.8e-48 163.1 0.0 9e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC89347.1 - 3.8e-21 75.7 0.0 8e-21 74.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PAM2 PF07145.10 EMC89347.1 - 5.4e-05 22.4 0.0 0.00013 21.1 0.0 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Kelch_1 PF01344.20 EMC89348.1 - 1.6e-44 149.1 15.1 7e-11 41.5 0.0 6.9 7 1 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 EMC89348.1 - 2.6e-32 109.6 3.9 4.5e-05 23.4 0.0 6.5 1 1 5 6 6 6 6 Kelch motif BTB PF00651.26 EMC89348.1 - 1.7e-27 95.5 0.5 9.1e-27 93.2 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.1 EMC89348.1 - 2.4e-22 78.4 7.8 0.00032 20.4 0.0 5.8 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC89348.1 - 4.6e-22 76.8 6.0 7.7e-05 22.3 0.2 6.6 6 0 0 6 6 6 4 Kelch motif BACK PF07707.10 EMC89348.1 - 2.7e-21 75.3 0.3 5.2e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 EMC89348.1 - 6.2e-19 67.6 1.0 0.0067 16.5 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC89348.1 - 1.2e-17 63.4 3.3 6.2e-06 26.0 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Cofilin_ADF PF00241.15 EMC89349.1 - 5.8e-11 42.3 0.1 6.9e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TLD PF07534.11 EMC89351.1 - 9e-40 135.8 0.3 1.4e-39 135.2 0.2 1.3 1 0 0 1 1 1 1 TLD E1-E2_ATPase PF00122.15 EMC89352.1 - 1.5e-74 249.9 0.5 1.5e-74 249.9 0.4 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC89352.1 - 5.8e-44 149.7 7.0 5.8e-44 149.7 4.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC89352.1 - 4.2e-25 89.4 0.0 3e-24 86.6 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC89352.1 - 5.7e-17 61.4 0.3 2e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMC89352.1 - 1.6e-16 59.5 0.1 3.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC89352.1 - 2.8e-10 40.6 0.0 9e-10 39.0 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC89352.1 - 0.00021 20.9 2.8 0.00081 19.0 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3329 PF11808.3 EMC89352.1 - 0.092 12.8 0.9 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Pox_F12L PF03337.8 EMC89352.1 - 0.18 9.7 0.0 0.28 9.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F12L protein WAP PF00095.16 EMC89353.1 - 1.8e-06 27.7 15.2 1.8e-06 27.7 10.5 2.3 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' BTB_2 PF02214.17 EMC89354.1 - 6.4e-26 90.3 0.1 1.4e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 EMC89355.1 - 0.068 12.4 0.1 0.072 12.3 0.1 1.1 1 0 0 1 1 1 0 Ion transport protein HSBP1 PF06825.7 EMC89356.1 - 2.8e-23 81.2 3.2 5.3e-23 80.3 2.2 1.4 1 1 0 1 1 1 1 Heat shock factor binding protein 1 EURL PF06937.6 EMC89356.1 - 0.0039 16.6 0.1 0.0043 16.5 0.1 1.0 1 0 0 1 1 1 1 EURL protein CALCOCO1 PF07888.6 EMC89356.1 - 0.018 13.3 0.2 0.019 13.3 0.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Matrilin_ccoil PF10393.4 EMC89356.1 - 0.15 11.4 0.9 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FlaC_arch PF05377.6 EMC89356.1 - 0.19 11.6 2.8 0.48 10.3 0.4 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 EMC89356.1 - 0.23 11.2 0.6 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper UPF0184 PF03670.8 EMC89356.1 - 0.24 11.5 1.2 0.35 11.0 0.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Cadherin PF00028.12 EMC89357.1 - 3.9e-71 235.3 3.7 1.4e-19 70.1 0.0 4.2 4 0 0 4 4 4 4 Cadherin domain MPP6 PF10175.4 EMC89358.1 - 3.1e-33 114.2 7.6 3.1e-33 114.2 5.2 1.8 2 0 0 2 2 2 1 M-phase phosphoprotein 6 FAM117 PF15388.1 EMC89358.1 - 0.062 12.5 0.4 0.077 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Acetyltransf_2 PF00797.12 EMC89359.1 - 1.7e-92 309.3 0.5 1.9e-92 309.1 0.3 1.0 1 0 0 1 1 1 1 N-acetyltransferase DUF553 PF04473.7 EMC89359.1 - 0.017 14.3 1.1 2.1 7.5 0.0 2.6 2 1 0 2 2 2 0 Transglutaminase-like domain Acetyltransf_2 PF00797.12 EMC89360.1 - 8.5e-87 290.7 0.0 9.7e-87 290.5 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase YhjQ PF06564.7 EMC89360.1 - 0.015 14.6 0.0 0.04 13.2 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein ComC PF03047.9 EMC89360.1 - 0.039 13.3 1.9 1.6 8.2 0.5 2.8 2 1 0 2 2 2 0 COMC family Acetyltransf_2 PF00797.12 EMC89361.1 - 8e-89 297.3 0.1 9.1e-89 297.1 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase adh_short PF00106.20 EMC89362.1 - 2.3e-27 95.9 1.6 3.1e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC89362.1 - 5.4e-10 39.4 0.0 8.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC89362.1 - 4.9e-05 23.0 0.7 9.6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 EMC89362.1 - 0.00062 19.0 0.0 0.0017 17.5 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMC89362.1 - 0.1 12.3 1.5 0.22 11.3 0.1 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EMC89363.1 - 7.2e-71 238.1 0.0 9.2e-71 237.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMC89363.1 - 1.1e-24 87.1 0.0 1.6e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC89363.1 - 9e-11 41.1 0.0 1.2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMC89363.1 - 8.4e-09 34.7 0.0 1.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMC89363.1 - 4.5e-08 33.3 0.0 6.8e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMC89363.1 - 2.9e-06 26.4 0.2 9.7e-06 24.6 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein PI-PLC-X PF00388.14 EMC89364.1 - 1.3e-66 222.5 0.1 2.8e-66 221.4 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.19 EMC89364.1 - 1.1e-46 156.5 0.3 9.2e-25 86.2 0.0 2.9 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.14 EMC89364.1 - 1.7e-41 140.8 0.0 5.3e-41 139.3 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EMC89364.1 - 3.8e-14 52.2 0.0 3.1e-13 49.3 0.0 2.5 2 0 0 2 2 2 1 C2 domain SH3_1 PF00018.23 EMC89364.1 - 3.9e-13 48.5 0.1 1.2e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMC89364.1 - 4.1e-12 45.4 0.1 1.4e-11 43.8 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC89364.1 - 7.7e-09 35.6 1.8 0.031 14.4 0.1 3.9 3 0 0 3 3 3 2 PH domain SH3_2 PF07653.12 EMC89364.1 - 1e-05 24.8 0.0 2.7e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain GDPD PF03009.12 EMC89364.1 - 0.015 14.8 0.6 0.043 13.3 0.0 2.1 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_like PF09279.6 EMC89364.1 - 0.036 14.0 4.4 0.038 14.0 0.2 3.0 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Kelch_1 PF01344.20 EMC89365.1 - 5.3e-39 131.5 3.0 1.3e-10 40.6 0.0 6.3 6 0 0 6 6 6 4 Kelch motif BACK PF07707.10 EMC89365.1 - 2.3e-29 101.2 1.5 4.5e-29 100.3 0.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 EMC89365.1 - 1.3e-23 82.0 5.3 2.8e-07 30.4 0.0 7.0 4 2 3 7 7 7 3 Kelch motif Kelch_4 PF13418.1 EMC89365.1 - 4.5e-19 67.9 3.8 9.1e-08 31.7 0.0 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC89365.1 - 5e-14 51.4 0.8 0.022 14.5 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 EMC89365.1 - 1.5e-12 47.3 0.6 0.00058 19.9 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain BTB PF00651.26 EMC89365.1 - 1.3e-10 41.2 0.4 2.6e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 EMC89365.1 - 1e-08 34.9 1.4 0.12 12.4 0.0 5.3 6 0 0 6 6 6 3 Kelch motif DUF1668 PF07893.8 EMC89365.1 - 0.0051 15.9 0.0 0.51 9.4 0.0 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF1668) Skp1 PF01466.14 EMC89365.1 - 0.14 12.2 0.2 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain RPE65 PF03055.10 EMC89366.1 - 6.8e-132 440.4 0.6 7.6e-132 440.2 0.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF4096 PF13340.1 EMC89366.1 - 0.1 12.4 0.3 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) GCV_H PF01597.14 EMC89367.1 - 9.6e-48 160.8 0.1 1.1e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein zf-C2H2_4 PF13894.1 EMC89368.1 - 3.5e-05 23.8 11.3 0.091 13.1 0.2 4.1 2 1 1 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC89368.1 - 0.012 15.8 12.4 0.4 11.1 0.4 4.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type CENP-N PF05238.8 EMC89369.1 - 2.6e-72 244.0 2.3 7.7e-72 242.5 1.6 1.7 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Glyco_hydro_65m PF03632.10 EMC89369.1 - 0.034 12.8 0.8 0.057 12.0 0.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Cmc1 PF08583.5 EMC89370.1 - 9e-16 57.4 4.8 1.1e-15 57.1 3.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3452 PF11934.3 EMC89370.1 - 0.013 14.8 0.1 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF755 PF05501.6 EMC89370.1 - 0.03 14.3 2.2 0.037 14.0 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF217 PF02697.9 EMC89370.1 - 0.048 13.9 1.0 0.061 13.5 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, COG1753 GCK PF07802.6 EMC89370.1 - 1.3 9.1 4.8 9.9 6.3 0.2 2.3 1 1 0 2 2 2 0 GCK domain Robl_LC7 PF03259.12 EMC89372.1 - 7.9e-27 92.6 0.0 8.6e-27 92.5 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF1762 PF08574.5 EMC89373.1 - 9.6e-06 25.9 21.2 9.6e-06 25.9 14.7 3.3 4 1 0 4 4 4 1 Protein of unknown function (DUF1762) AA_permease_2 PF13520.1 EMC89374.1 - 3.5e-66 223.4 40.1 4.4e-66 223.1 27.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC89374.1 - 4.2e-28 97.9 32.0 4.2e-28 97.9 22.2 1.3 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EMC89375.1 - 1.5e-26 93.1 0.0 1.7e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89375.1 - 8.6e-26 90.5 0.0 1.1e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC89375.1 - 0.025 13.6 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC89375.1 - 0.034 13.8 0.6 0.087 12.5 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pyr_redox_3 PF13738.1 EMC89376.1 - 3e-11 43.7 0.0 6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC89376.1 - 2.7e-05 24.1 0.0 5.4e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S8 PF00082.17 EMC89377.1 - 3.4e-43 147.8 0.0 4.8e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family adh_short PF00106.20 EMC89378.1 - 8.6e-26 90.8 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC89378.1 - 2e-11 44.1 0.3 2.7e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC89378.1 - 2.7e-06 27.1 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC89378.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMC89378.1 - 0.00053 18.9 0.2 0.0025 16.7 0.0 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EMC89378.1 - 0.0023 16.9 0.0 0.0042 16.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMC89378.1 - 0.035 13.5 0.4 0.25 10.7 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 EMC89378.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LRR_8 PF13855.1 EMC89379.1 - 2.2e-23 81.7 37.6 1.3e-08 34.4 1.3 3.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EMC89379.1 - 2.3e-19 68.5 18.2 4e-07 29.5 0.3 4.4 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMC89379.1 - 9.1e-08 31.4 8.9 0.026 14.5 0.1 5.4 4 1 1 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.1 EMC89379.1 - 1.4e-07 31.2 2.7 2.2e-07 30.6 1.8 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EMC89379.1 - 1.3e-06 27.5 15.0 1.6 9.0 0.1 6.6 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC89379.1 - 1.6e-05 24.3 12.7 0.79 10.1 0.0 6.8 6 1 1 7 7 7 2 Leucine rich repeat HSF_DNA-bind PF00447.12 EMC89380.1 - 7.2e-36 122.5 0.1 1.4e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Vert_HS_TF PF06546.6 EMC89380.1 - 4.6e-18 65.5 0.0 7.1e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Vertebrate heat shock transcription factor DUF904 PF06005.7 EMC89380.1 - 2 8.7 9.6 6.2 7.2 6.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) F-box-like PF12937.2 EMC89381.1 - 1.8e-14 53.1 1.1 2e-14 53.0 0.7 1.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC89381.1 - 1.2e-08 34.3 0.1 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EMC89381.1 - 0.0027 17.6 0.1 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 PRANC domain TRADD_N PF09034.5 EMC89382.1 - 3.1e-41 139.8 3.1 5.2e-41 139.1 2.2 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain Death PF00531.17 EMC89382.1 - 2.2e-09 36.9 1.1 3.6e-09 36.2 0.2 1.8 2 0 0 2 2 2 1 Death domain Galactosyl_T PF01762.16 EMC89383.1 - 5.9e-46 156.5 0.0 7.3e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC89383.1 - 8.8e-09 34.9 0.0 1.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like UPF0183 PF03676.9 EMC89384.1 - 2.3e-184 612.5 0.8 2.7e-184 612.3 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CBF_beta PF02312.12 EMC89385.1 - 2.6e-47 160.5 0.0 2.9e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit DUF1204 PF06721.6 EMC89385.1 - 0.73 9.0 4.8 0.97 8.6 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) G-alpha PF00503.15 EMC89386.1 - 3.5e-116 388.0 3.2 3.9e-116 387.9 2.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMC89386.1 - 3e-13 49.3 0.0 7.1e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC89386.1 - 0.00096 18.3 0.5 0.0015 17.7 0.3 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DDE_Tnp_1_assoc PF13808.1 EMC89386.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-associated zf-RING_2 PF13639.1 EMC89387.1 - 4.7e-15 55.1 8.6 7.6e-15 54.4 4.4 2.3 2 0 0 2 2 2 1 Ring finger domain CUE PF02845.11 EMC89387.1 - 1.3e-10 40.5 0.1 2.7e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.1 EMC89387.1 - 1.4e-09 37.4 3.3 3.1e-09 36.3 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC89387.1 - 5e-09 36.0 5.7 1.5e-08 34.5 4.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC89387.1 - 3.7e-08 32.8 5.2 7.3e-08 31.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC89387.1 - 3.9e-08 33.2 8.4 2.7e-07 30.6 5.1 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC89387.1 - 2.9e-06 26.8 3.8 6.1e-06 25.8 2.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMC89387.1 - 2.3e-05 24.1 0.6 7.3e-05 22.5 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMC89387.1 - 0.0011 18.7 4.4 0.0021 17.8 3.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC89387.1 - 0.002 17.7 4.5 0.0059 16.2 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 EMC89387.1 - 0.24 11.4 7.7 0.56 10.2 5.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EMC89387.1 - 0.32 10.6 2.4 1 9.0 1.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EMC89387.1 - 0.39 10.6 5.6 1.2 9.1 3.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain NUDIX_2 PF13869.1 EMC89388.1 - 1.6e-74 249.2 0.0 1.9e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 EMC89388.1 - 0.014 15.0 0.1 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 NUDIX domain Metallothio PF00131.15 EMC89389.1 - 1.4e-13 50.4 63.0 1.5e-13 50.3 43.7 1.0 1 0 0 1 1 1 1 Metallothionein Metallothio PF00131.15 EMC89390.1 - 4.7e-13 48.8 63.9 5.1e-13 48.6 44.3 1.0 1 0 0 1 1 1 1 Metallothionein Nic96 PF04097.9 EMC89391.1 - 6.5e-196 652.1 0.7 8e-196 651.8 0.5 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Apc3 PF12895.2 EMC89391.1 - 0.34 11.0 4.8 0.54 10.4 0.3 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BCNT PF07572.7 EMC89392.1 - 5.7e-29 99.8 0.7 5.7e-29 99.8 0.5 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF3513 PF12026.3 EMC89393.1 - 4.8e-90 300.7 0.2 8.5e-90 299.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3513) Serine_rich PF08824.5 EMC89393.1 - 5.4e-60 201.7 0.7 1.1e-59 200.7 0.0 1.9 3 0 0 3 3 3 1 Serine rich protein interaction domain SH3_1 PF00018.23 EMC89393.1 - 3.7e-14 51.8 0.1 9.5e-14 50.5 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC89393.1 - 1.8e-13 49.8 0.5 7.3e-13 47.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMC89393.1 - 4.9e-10 38.7 0.0 1.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Neurokinin_B PF03823.9 EMC89393.1 - 0.81 9.4 7.8 16 5.3 0.0 4.8 3 1 2 5 5 5 0 Neurokinin B Trypsin PF00089.21 EMC89394.1 - 1.2e-72 244.0 0.7 1.4e-72 243.8 0.5 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC89394.1 - 1.4e-05 24.5 0.0 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 EMC89394.1 - 0.006 15.9 0.0 0.11 11.8 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF316) Trypsin_2 PF13365.1 EMC89394.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain WD40 PF00400.27 EMC89395.1 - 3.6e-18 64.6 17.6 2.5e-06 27.1 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EMC89395.1 - 8.7e-05 22.3 0.8 0.14 11.8 0.1 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-rbx1 PF12678.2 EMC89395.1 - 0.34 11.0 11.3 1.4 9.0 7.8 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EMC89395.1 - 0.38 10.6 14.5 0.023 14.5 4.4 2.9 2 0 0 2 2 2 0 Ring finger domain Pkinase_Tyr PF07714.12 EMC89396.1 - 6.9e-44 149.8 0.1 2.5e-41 141.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EMC89396.1 - 8e-33 113.6 0.1 2.3e-32 112.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain CENP-F_leu_zip PF10473.4 EMC89396.1 - 0.032 14.0 0.2 0.032 14.0 0.1 2.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glu-tRNAGln PF02686.10 EMC89396.1 - 0.04 13.7 0.1 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Cys_rich_FGFR PF00839.12 EMC89397.1 - 3e-210 680.3 119.4 1.9e-19 69.3 1.4 15.3 16 0 0 16 16 16 15 Cysteine rich repeat UME PF08064.8 EMC89397.1 - 0.8 9.6 4.7 18 5.3 0.0 4.7 6 0 0 6 6 6 0 UME (NUC010) domain DUF445 PF04286.7 EMC89397.1 - 5.1 6.5 7.6 2.8 7.3 3.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DAO PF01266.19 EMC89398.1 - 8.2e-72 242.0 0.0 1.1e-71 241.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 EMC89398.1 - 5e-55 186.1 0.0 9.1e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMC89398.1 - 7.4e-21 73.9 0.0 2.1e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.19 EMC89398.1 - 2.2e-08 33.3 0.5 6.3e-08 31.8 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC89398.1 - 1.3e-07 31.8 0.8 1.3e-05 25.4 0.6 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EMC89398.1 - 3.9e-05 22.9 0.3 0.053 12.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_oxidored PF12831.2 EMC89398.1 - 4.5e-05 22.6 0.8 0.0001 21.5 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMC89398.1 - 0.00023 19.9 0.8 0.029 13.0 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EMC89398.1 - 0.00029 19.9 1.6 0.0014 17.7 1.2 2.0 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMC89398.1 - 0.00036 20.4 0.1 0.026 14.4 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMC89398.1 - 0.0019 18.1 0.4 0.0062 16.5 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMC89398.1 - 0.0025 16.9 0.4 0.054 12.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EMC89398.1 - 0.0045 15.5 0.4 0.022 13.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.15 EMC89398.1 - 0.0063 16.6 0.0 0.042 13.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMC89398.1 - 0.011 16.1 1.1 1.2 9.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMC89398.1 - 0.056 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EMC89398.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMC89398.1 - 0.23 11.1 0.1 0.42 10.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_29 PF00777.13 EMC89399.1 - 2.9e-99 331.5 0.0 3.4e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.16 EMC89399.1 - 0.019 13.4 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase MIase PF02426.11 EMC89399.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Muconolactone delta-isomerase Fucokinase PF07959.7 EMC89400.1 - 3.3e-97 325.6 0.0 4.3e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.8 EMC89400.1 - 5.7e-08 32.8 0.1 1.6e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EMC89400.1 - 1.5e-06 28.2 0.2 3.5e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain COG4 PF08318.7 EMC89401.1 - 1.6e-99 332.8 7.2 2.6e-99 332.1 5.0 1.3 1 0 0 1 1 1 1 COG4 transport protein DUF3647 PF12363.3 EMC89401.1 - 0.0041 17.1 0.3 2.3 8.3 0.1 3.3 2 0 0 2 2 2 2 Phage protein COG5 PF10392.4 EMC89401.1 - 0.49 10.3 6.1 2 8.3 0.1 3.2 2 1 1 3 3 3 0 Golgi transport complex subunit 5 CPSF_A PF03178.10 EMC89402.1 - 1.7e-100 336.2 0.0 1.2e-97 326.9 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 EMC89402.1 - 4.7e-79 265.8 0.0 1.1e-78 264.5 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term IL34 PF15036.1 EMC89403.1 - 1.5e-49 167.8 3.9 1.6e-49 167.7 2.7 1.0 1 0 0 1 1 1 1 Interleukin 34 IMD PF08397.6 EMC89404.1 - 5.9e-85 284.0 1.4 8.6e-85 283.4 1.0 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain DUF3987 PF13148.1 EMC89404.1 - 0.02 13.4 0.9 0.039 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vac14_Fig4_bd PF11916.3 EMC89405.1 - 2.6e-78 261.3 8.6 4.5e-78 260.5 5.9 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EMC89405.1 - 1.8e-45 153.2 0.2 3e-40 136.5 0.0 4.2 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EMC89405.1 - 5.5e-09 35.3 0.4 0.005 16.8 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EMC89405.1 - 1.8e-07 31.4 0.2 0.099 13.1 0.0 5.2 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 EMC89405.1 - 3.2e-07 30.5 0.0 0.32 11.2 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EMC89405.1 - 0.0048 16.7 1.3 2.6 7.8 0.0 3.9 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Motile_Sperm PF00635.21 EMC89406.1 - 2.1e-07 30.5 0.1 0.0011 18.5 0.0 2.7 3 0 0 3 3 3 2 MSP (Major sperm protein) domain MYCBPAP PF14646.1 EMC89406.1 - 0.00031 19.5 1.0 0.77 8.4 0.0 3.7 4 1 0 4 4 4 2 MYCBP-associated protein family PapD-like PF14874.1 EMC89406.1 - 0.094 12.6 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Flagellar-associated PapD-like PNP_UDP_1 PF01048.15 EMC89407.1 - 1.1e-48 165.3 0.0 1.2e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily EF-hand_1 PF00036.27 EMC89408.1 - 3.9e-26 88.3 4.4 1.2e-06 27.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EMC89408.1 - 3.7e-23 79.2 4.1 1.2e-05 24.7 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EMC89408.1 - 1.3e-22 79.7 4.6 5.8e-11 42.3 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC89408.1 - 2.1e-18 64.7 2.7 0.00074 18.7 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EMC89408.1 - 3.3e-09 36.2 5.0 6e-06 25.7 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_10 PF14788.1 EMC89408.1 - 0.00034 20.2 0.6 0.56 9.9 0.0 3.6 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 EMC89408.1 - 0.015 15.3 0.0 3.4 7.7 0.0 3.0 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Aa_trans PF01490.13 EMC89409.1 - 4e-55 186.9 24.0 5e-55 186.6 16.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMC89409.1 - 3.4e-07 29.4 21.8 8.6e-07 28.1 10.9 2.3 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Rubis-subs-bind PF09273.6 EMC89411.1 - 1.2e-07 31.6 2.9 1.9e-07 31.0 2.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding YlbD_coat PF14071.1 EMC89411.1 - 0.017 15.1 1.1 0.032 14.2 0.7 1.4 1 0 0 1 1 1 0 Putative coat protein SET PF00856.23 EMC89411.1 - 0.18 12.0 0.5 0.51 10.6 0.0 1.9 2 1 0 2 2 2 0 SET domain Pkinase PF00069.20 EMC89412.1 - 1.5e-71 240.5 0.1 2.4e-71 239.9 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89412.1 - 1.1e-41 142.7 0.0 1.5e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC89412.1 - 3.1e-08 32.9 0.0 7.4e-07 28.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EMC89412.1 - 0.0084 15.1 0.1 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EMC89412.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase vATP-synt_AC39 PF01992.11 EMC89413.1 - 2.5e-113 378.6 0.0 2.8e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit adh_short PF00106.20 EMC89414.1 - 9.6e-27 93.9 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC89414.1 - 2.7e-13 50.2 0.0 4.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC89414.1 - 9.4e-06 25.3 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMC89414.1 - 0.0073 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Na_H_Exchanger PF00999.16 EMC89415.1 - 1.4e-60 204.8 30.9 1.6e-60 204.6 21.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family p25-alpha PF05517.7 EMC89416.1 - 1.3e-58 197.5 6.3 1.5e-58 197.4 4.4 1.0 1 0 0 1 1 1 1 p25-alpha DnaB PF00772.16 EMC89416.1 - 0.0096 15.7 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase N terminal domain EF-hand_1 PF00036.27 EMC89416.1 - 0.21 11.0 0.6 4.2 6.9 0.0 2.9 3 0 0 3 3 3 0 EF hand EGF_CA PF07645.10 EMC89418.1 - 2.8e-16 59.2 48.3 1.8e-07 30.9 5.1 5.7 5 2 1 6 6 6 4 Calcium-binding EGF domain EGF PF00008.22 EMC89418.1 - 1.1e-12 47.6 16.4 1.6e-10 40.7 3.4 6.7 5 3 3 8 8 8 2 EGF-like domain cEGF PF12662.2 EMC89418.1 - 1.1e-10 40.9 6.7 5.8e-09 35.4 0.4 6.4 6 1 0 6 6 6 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EMC89418.1 - 2.5e-09 37.1 46.4 1.6e-07 31.3 3.2 5.4 4 1 0 5 5 5 3 Coagulation Factor Xa inhibitory site Sushi PF00084.15 EMC89418.1 - 2.5e-09 37.3 0.3 2.5e-09 37.3 0.2 4.9 4 1 1 5 5 5 1 Sushi domain (SCR repeat) EGF_2 PF07974.8 EMC89418.1 - 0.0095 16.0 13.9 0.0095 16.0 9.7 5.6 5 0 0 5 5 5 1 EGF-like domain hEGF PF12661.2 EMC89418.1 - 0.029 14.4 4.7 0.029 14.4 3.2 6.0 6 0 0 6 6 6 0 Human growth factor-like EGF EGF_3 PF12947.2 EMC89418.1 - 0.33 10.9 0.0 0.33 10.9 0.0 6.1 6 1 1 7 7 7 0 EGF domain RRM_6 PF14259.1 EMC89419.1 - 6.2e-09 35.7 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC89419.1 - 1.2e-07 31.2 0.0 2.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.2 EMC89419.1 - 1.3 9.5 55.6 5 7.7 38.5 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Lys PF00062.15 EMC89420.1 - 2.7e-05 24.1 2.1 0.0025 17.8 1.0 2.0 2 0 0 2 2 2 2 C-type lysozyme/alpha-lactalbumin family YEATS PF03366.11 EMC89421.1 - 1e-32 111.7 0.7 1.7e-32 110.9 0.5 1.4 1 0 0 1 1 1 1 YEATS family DUF3166 PF11365.3 EMC89421.1 - 0.0073 16.7 0.5 0.017 15.5 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3166) DUF1664 PF07889.7 EMC89421.1 - 0.016 15.0 1.5 0.028 14.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DNA_pol3_gamma3 PF12169.3 EMC89421.1 - 0.07 12.8 0.2 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III DUF342 PF03961.8 EMC89421.1 - 0.18 10.1 2.2 0.23 9.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 EMC89421.1 - 0.41 10.0 6.2 0.42 10.0 3.5 1.5 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF904 PF06005.7 EMC89421.1 - 0.59 10.4 6.4 0.2 11.9 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EMC89421.1 - 0.82 9.2 3.5 1.9 8.0 2.4 1.7 1 0 0 1 1 1 0 Septum formation initiator IRS PF02174.12 EMC89422.1 - 4.9e-27 93.4 0.1 9.9e-27 92.4 0.1 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Exo_endo_phos PF03372.18 EMC89423.1 - 1.7e-09 37.9 0.1 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_cc PF11790.3 EMC89423.1 - 0.0011 18.5 1.5 0.41 10.0 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase catalytic core UQ_con PF00179.21 EMC89423.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme 7tm_1 PF00001.16 EMC89424.1 - 9.4e-51 172.4 11.9 1.1e-50 172.1 8.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC89424.1 - 8.9e-08 31.5 8.8 1.1e-07 31.3 6.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC89424.1 - 1.5e-07 30.8 4.3 1.9e-07 30.5 2.9 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 EMC89424.1 - 0.00012 21.3 5.9 0.00043 19.4 4.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_2 PF00002.19 EMC89424.1 - 0.23 10.5 12.1 0.84 8.6 8.4 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) 7tm_4 PF13853.1 EMC89424.1 - 0.27 11.0 11.8 0.016 14.9 2.6 2.9 2 1 1 3 3 3 0 Olfactory receptor HrpB4 PF09502.5 EMC89425.1 - 0.061 12.5 0.1 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) DUF4401 PF14351.1 EMC89425.1 - 0.11 11.4 0.2 0.12 11.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) LCE PF14672.1 EMC89426.1 - 1.8 9.0 67.4 4.4 7.8 6.4 5.2 1 1 4 5 5 5 0 Late cornified envelope Cornifin PF02389.10 EMC89427.1 - 1.9e-07 31.0 44.0 2.3e-07 30.7 30.5 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF1619 PF07773.6 EMC89428.1 - 1e-21 78.0 0.1 1.9e-20 73.8 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1619) M16C_assoc PF08367.6 EMC89429.1 - 1.1e-84 283.1 0.0 3.6e-84 281.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EMC89429.1 - 3.8e-32 111.4 0.0 2.3e-20 73.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMC89429.1 - 1.8e-09 37.5 0.6 4.4e-05 23.2 0.0 3.9 5 0 0 5 5 5 2 Insulinase (Peptidase family M16) DUF3007 PF11460.3 EMC89429.1 - 0.0078 16.2 0.4 0.021 14.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) zf-C2H2 PF00096.21 EMC89430.1 - 1.1e-12 47.4 31.8 0.00019 21.6 6.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC89430.1 - 7.9e-11 41.6 13.3 8.5e-07 28.9 4.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC89430.1 - 1.7e-07 31.1 29.5 0.0097 16.1 1.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMC89430.1 - 0.35 11.2 0.1 0.35 11.2 0.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EMC89430.1 - 3.3 7.9 10.0 11 6.2 1.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Connexin PF00029.14 EMC89432.1 - 5.5e-32 110.0 1.3 1e-31 109.1 0.9 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC89432.1 - 9.2e-26 89.4 2.5 9.2e-26 89.4 1.7 2.3 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Cyclin_N PF00134.18 EMC89433.1 - 1.5e-14 53.6 0.2 3e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EMC89433.1 - 7.1e-13 49.2 0.1 1.1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin bZIP_1 PF00170.16 EMC89434.1 - 4.1e-20 71.5 12.6 7.5e-20 70.6 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.12 EMC89434.1 - 2.2e-18 65.1 1.2 5.7e-18 63.8 0.8 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.10 EMC89434.1 - 1.4e-07 31.2 10.8 2.4e-07 30.4 7.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC89434.1 - 0.0021 18.3 6.2 0.0042 17.3 4.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF3534 PF12053.3 EMC89435.1 - 4.9e-69 230.7 0.1 4.9e-69 230.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3534) PDZ PF00595.19 EMC89435.1 - 1.5e-38 130.7 5.7 4e-16 58.9 0.1 3.7 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC89435.1 - 1.7e-15 56.6 1.1 3.5e-07 30.0 0.1 3.9 3 1 0 3 3 3 3 PDZ domain Integrin_beta PF00362.13 EMC89436.1 - 9e-193 640.9 0.7 9e-193 640.9 0.5 2.0 2 0 0 2 2 2 1 Integrin, beta chain Integrin_b_cyt PF08725.6 EMC89436.1 - 4.4e-24 83.6 0.2 8.1e-24 82.7 0.1 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 EMC89436.1 - 4.8e-24 84.5 7.8 4.8e-24 84.5 5.4 4.7 6 1 1 7 7 7 1 Integrin beta tail domain EGF_2 PF07974.8 EMC89436.1 - 2.4e-09 37.1 59.3 5.2e-06 26.5 11.2 7.3 6 1 1 7 7 7 3 EGF-like domain E_Pc_C PF06752.7 EMC89437.1 - 1.3e-96 322.5 28.6 2.7e-96 321.5 19.9 1.5 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus EPL1 PF10513.4 EMC89437.1 - 1.5e-17 64.2 1.1 1.5e-17 64.2 0.8 3.3 3 0 0 3 3 3 2 Enhancer of polycomb-like RhoGAP PF00620.22 EMC89438.1 - 1.4e-49 167.6 0.1 1.4e-49 167.6 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EMC89438.1 - 9.9e-09 35.3 0.5 4.1e-08 33.3 0.3 2.1 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 EMC89438.1 - 1.5e-07 30.8 0.0 3.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC89438.1 - 1.2e-05 24.6 0.9 0.00015 21.0 0.2 2.6 2 0 0 2 2 2 1 SH3 domain PH_9 PF15410.1 EMC89438.1 - 3.6e-05 23.8 0.4 0.00012 22.2 0.3 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain WW PF00397.21 EMC89438.1 - 0.0002 21.1 4.8 0.0002 21.1 3.3 4.2 3 1 1 4 4 4 2 WW domain zf-H2C2_2 PF13465.1 EMC89439.1 - 9.7e-34 114.0 55.6 1.1e-08 34.9 1.6 7.8 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89439.1 - 6.5e-23 79.6 70.1 0.0003 20.9 3.4 7.7 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89439.1 - 7.4e-17 60.3 54.5 0.0016 18.6 1.0 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89439.1 - 1.1e-13 50.8 48.3 0.0015 18.6 0.9 7.7 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC89439.1 - 8.7e-09 35.2 45.8 0.025 14.7 0.9 6.7 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC89439.1 - 1e-08 35.1 25.2 3.9e-07 30.0 1.0 3.8 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding Homeobox PF00046.24 EMC89439.1 - 1.7e-05 24.3 0.0 4.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_6 PF13912.1 EMC89439.1 - 0.00014 21.6 57.6 0.053 13.4 0.5 7.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC89439.1 - 1.8 8.7 46.1 0.057 13.5 0.7 7.0 3 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) DUF1610 PF07754.6 EMC89439.1 - 3 8.0 11.4 5.9 7.0 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) RVT_1 PF00078.22 EMC89441.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.1 EMC89443.1 - 7.9e-09 35.3 27.8 6.6e-05 23.0 2.3 5.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC89443.1 - 0.0033 17.6 49.2 0.43 11.0 1.6 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC89443.1 - 0.011 16.0 4.0 0.011 16.0 2.8 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type JCAD PF15351.1 EMC89444.1 - 0 1775.1 66.8 0 1768.1 46.3 2.0 1 1 0 1 1 1 1 Junctional protein associated with coronary artery disease PAP_assoc PF03828.14 EMC89445.1 - 4.5e-07 29.7 0.4 1.1e-06 28.4 0.3 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase RRM_5 PF13893.1 EMC89445.1 - 0.017 14.9 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EMC89446.1 - 1.6e-52 178.2 0.0 2.3e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89446.1 - 2.6e-25 88.9 0.0 5.7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMC89446.1 - 0.032 13.9 0.1 0.12 12.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC89446.1 - 0.083 11.8 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 EMC89446.1 - 0.13 11.6 0.2 0.34 10.2 0.0 1.7 1 1 1 2 2 2 0 RIO1 family BAMBI PF06211.7 EMC89447.1 - 2.1e-46 156.3 11.2 2.1e-46 156.3 7.8 1.7 2 0 0 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.18 EMC89447.1 - 0.00014 22.4 10.8 0.00014 22.4 7.5 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain DUF1049 PF06305.6 EMC89447.1 - 0.12 11.8 1.0 0.22 11.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) YajC PF02699.10 EMC89447.1 - 0.15 11.7 0.2 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit KASH PF10541.4 EMC89447.1 - 0.56 10.0 7.3 5.5 6.9 0.5 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain WW PF00397.21 EMC89448.1 - 9.5e-10 38.1 0.9 1.8e-09 37.2 0.6 1.5 1 0 0 1 1 1 1 WW domain DUF2968 PF11180.3 EMC89449.1 - 0.00016 21.1 4.3 0.0002 20.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Filament PF00038.16 EMC89449.1 - 0.00035 20.1 6.1 0.0004 19.9 4.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 EMC89449.1 - 0.0008 17.2 5.7 0.00083 17.2 3.9 1.0 1 0 0 1 1 1 1 Myosin tail Bacillus_HBL PF05791.6 EMC89449.1 - 0.00083 18.7 4.7 0.0012 18.2 3.3 1.4 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 EMC89449.1 - 0.0014 17.8 10.9 0.0052 16.0 5.7 1.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 EMC89449.1 - 0.0018 17.4 5.2 0.0021 17.2 3.6 1.1 1 0 0 1 1 1 1 Tropomyosin ERM PF00769.14 EMC89449.1 - 0.0026 17.3 4.4 0.003 17.1 3.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF869 PF05911.6 EMC89449.1 - 0.0033 15.7 9.8 0.0039 15.5 6.8 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) ADIP PF11559.3 EMC89449.1 - 0.0038 17.1 7.6 0.0046 16.8 5.3 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4559 PF15112.1 EMC89449.1 - 0.0041 16.3 6.6 0.0048 16.1 4.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) DivIVA PF05103.8 EMC89449.1 - 0.0045 17.0 5.5 0.006 16.6 3.8 1.2 1 0 0 1 1 1 1 DivIVA protein Laminin_I PF06008.9 EMC89449.1 - 0.0057 16.0 4.7 0.0062 15.8 3.2 1.1 1 0 0 1 1 1 1 Laminin Domain I Tropomyosin_1 PF12718.2 EMC89449.1 - 0.0069 16.2 6.7 0.0078 16.0 4.6 1.1 1 0 0 1 1 1 1 Tropomyosin like Seryl_tRNA_N PF02403.17 EMC89449.1 - 0.0073 16.3 8.9 0.031 14.2 5.2 2.0 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EMC89449.1 - 0.0077 15.3 7.6 0.0088 15.1 5.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 YlqD PF11068.3 EMC89449.1 - 0.011 15.7 5.1 0.013 15.5 3.5 1.3 1 0 0 1 1 1 0 YlqD protein Lipoprotein_7 PF01540.11 EMC89449.1 - 0.012 14.7 1.6 0.013 14.5 1.1 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein zf-C4H2 PF10146.4 EMC89449.1 - 0.013 15.5 2.9 0.014 15.4 2.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3393 PF11873.3 EMC89449.1 - 0.013 15.0 0.8 0.015 14.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) HR1 PF02185.11 EMC89449.1 - 0.013 15.2 5.3 0.013 15.2 3.6 1.9 1 1 1 2 2 2 0 Hr1 repeat DUF972 PF06156.8 EMC89449.1 - 0.019 15.2 7.2 0.031 14.6 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4047 PF13256.1 EMC89449.1 - 0.02 14.8 4.5 0.025 14.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) H-kinase_dim PF02895.9 EMC89449.1 - 0.023 15.0 3.3 0.095 13.0 2.3 1.9 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain OmpH PF03938.9 EMC89449.1 - 0.034 14.1 3.7 0.04 13.8 2.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Herpes_UL6 PF01763.11 EMC89449.1 - 0.036 12.2 3.0 0.038 12.1 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like AAA_13 PF13166.1 EMC89449.1 - 0.04 12.3 4.2 0.041 12.3 2.9 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EMC89449.1 - 0.04 13.4 8.6 0.052 13.1 6.0 1.2 1 0 0 1 1 1 0 IncA protein Rootletin PF15035.1 EMC89449.1 - 0.059 13.3 7.9 0.074 13.0 5.4 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 EMC89449.1 - 0.069 12.3 0.3 0.081 12.0 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4140 PF13600.1 EMC89449.1 - 0.081 13.3 0.8 0.081 13.3 0.6 1.6 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) rRNA_proc-arch PF13234.1 EMC89449.1 - 0.089 11.9 4.6 0.11 11.6 3.2 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain PEP-utilisers_N PF05524.8 EMC89449.1 - 0.097 12.4 1.1 0.13 12.0 0.8 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Prefoldin PF02996.12 EMC89449.1 - 0.1 12.2 6.9 0.075 12.6 3.2 1.9 1 1 0 1 1 1 0 Prefoldin subunit Kinesin-relat_1 PF12711.2 EMC89449.1 - 0.13 12.6 7.5 0.16 12.4 4.2 1.9 1 1 1 2 2 2 0 Kinesin motor UDPG_MGDP_dh PF00984.14 EMC89449.1 - 0.14 12.3 0.4 0.84 9.8 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Kinetocho_Slk19 PF12709.2 EMC89449.1 - 0.14 12.2 7.2 2.8 8.0 3.4 2.6 1 1 1 2 2 2 0 Central kinetochore-associated Striatin PF08232.7 EMC89449.1 - 0.15 12.3 5.8 0.19 12.0 4.0 1.1 1 0 0 1 1 1 0 Striatin family DUF1043 PF06295.7 EMC89449.1 - 0.16 11.5 3.9 0.18 11.4 2.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) bZIP_Maf PF03131.12 EMC89449.1 - 0.17 12.2 6.2 0.2 11.9 3.6 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor ArsC PF03960.10 EMC89449.1 - 0.17 11.9 2.1 0.48 10.5 0.1 2.3 1 1 2 3 3 3 0 ArsC family SlyX PF04102.7 EMC89449.1 - 0.18 12.2 7.4 0.25 11.7 4.2 1.9 1 1 1 2 2 2 0 SlyX DUF342 PF03961.8 EMC89449.1 - 0.19 10.0 6.9 0.21 9.9 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EMC89449.1 - 0.2 11.3 5.7 0.23 11.1 3.9 1.2 1 0 0 1 1 1 0 Mnd1 family Spc7 PF08317.6 EMC89449.1 - 0.2 10.2 11.1 0.61 8.6 7.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.6 EMC89449.1 - 0.22 11.4 4.9 0.57 10.0 2.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rho_Binding PF08912.6 EMC89449.1 - 0.22 11.8 9.4 0.48 10.7 5.3 2.1 1 1 1 2 2 2 0 Rho Binding Ax_dynein_light PF10211.4 EMC89449.1 - 0.23 11.2 8.3 0.41 10.4 5.6 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.14 EMC89449.1 - 0.25 9.1 3.3 0.25 9.1 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EMC89449.1 - 0.28 10.0 6.0 0.3 9.9 4.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2630 PF10944.3 EMC89449.1 - 0.3 11.2 5.7 0.44 10.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Baculo_PEP_C PF04513.7 EMC89449.1 - 0.33 10.7 4.5 0.49 10.2 3.1 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cortex-I_coil PF09304.5 EMC89449.1 - 0.35 10.9 10.1 0.41 10.7 6.7 1.3 1 1 0 1 1 1 0 Cortexillin I, coiled coil UPF0242 PF06785.6 EMC89449.1 - 0.42 9.2 7.1 0.46 9.1 4.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) CENP-F_leu_zip PF10473.4 EMC89449.1 - 0.49 10.2 11.7 0.89 9.4 8.1 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 EMC89449.1 - 0.5 10.3 9.9 0.74 9.7 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 EMC89449.1 - 0.52 10.6 13.3 3 8.1 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF2408 PF10303.4 EMC89449.1 - 0.54 10.3 7.4 0.85 9.7 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TBPIP PF07106.8 EMC89449.1 - 0.72 9.3 9.9 0.97 8.9 6.8 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2205 PF10224.4 EMC89449.1 - 0.77 9.3 6.0 2 8.0 4.1 1.8 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4600 PF15372.1 EMC89449.1 - 0.9 9.7 8.1 1 9.5 2.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) TMF_DNA_bd PF12329.3 EMC89449.1 - 0.94 9.3 10.8 53 3.7 7.5 2.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 EMC89449.1 - 0.97 9.2 8.3 1.1 9.0 3.8 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.4 EMC89449.1 - 1 9.5 3.7 1.7 8.8 2.3 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.3 EMC89449.1 - 1.5 8.0 7.2 1.6 7.9 4.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Sec2p PF06428.6 EMC89449.1 - 1.6 8.6 10.0 4.1 7.2 6.9 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cep57_CLD_2 PF14197.1 EMC89449.1 - 1.7 8.6 10.7 0.38 10.7 2.5 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 EMC89449.1 - 1.8 8.0 11.3 2.1 7.9 6.1 2.3 1 1 1 2 2 2 0 Septum formation initiator Spc24 PF08286.6 EMC89449.1 - 2.9 7.5 8.3 6.1 6.5 5.8 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Takusan PF04822.8 EMC89449.1 - 5 6.9 8.8 25 4.7 3.3 2.2 1 1 1 2 2 2 0 Takusan Guanylate_kin PF00625.16 EMC89450.1 - 1.1e-49 168.4 0.3 2.8e-48 163.7 0.2 2.2 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.11 EMC89450.1 - 4e-21 74.4 4.2 2.8e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 L27 domain PDZ PF00595.19 EMC89450.1 - 1.9e-13 50.3 1.0 3.9e-13 49.3 0.7 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 EMC89450.1 - 1.9e-07 30.4 0.0 4.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC89450.1 - 2.2e-07 30.1 0.4 2.1e-06 27.0 0.2 2.6 2 1 0 2 2 2 1 SH3 domain PDZ_2 PF13180.1 EMC89450.1 - 1.9e-05 24.4 0.1 6.4e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.1 EMC89450.1 - 2.9e-05 23.5 0.0 6.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.1 EMC89450.1 - 0.06 13.1 0.0 0.39 10.5 0.1 2.3 2 1 0 2 2 2 0 Tricorn protease PDZ domain Homeobox_KN PF05920.6 EMC89451.1 - 1e-14 53.9 0.2 2.1e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMC89451.1 - 2.8e-05 23.6 0.2 6.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMC89451.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Period_C PF12114.3 EMC89451.1 - 0.24 10.9 3.7 0.47 10.0 2.6 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region zf-H2C2_2 PF13465.1 EMC89453.1 - 4.7e-14 51.8 5.5 6.1e-07 29.4 0.8 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89453.1 - 2.7e-07 30.5 17.0 2.7e-07 30.5 0.4 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-HYPF PF07503.7 EMC89453.1 - 0.00071 18.9 1.8 0.34 10.3 0.1 2.2 2 0 0 2 2 2 2 HypF finger zf-LYAR PF08790.6 EMC89453.1 - 0.0019 17.8 4.4 0.013 15.1 0.3 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EMC89453.1 - 0.017 14.7 1.9 0.36 10.4 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain zf-C2H2_4 PF13894.1 EMC89453.1 - 0.018 15.3 0.2 0.018 15.3 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EMC89453.1 - 0.037 13.9 4.3 0.72 9.8 2.9 2.1 1 1 0 1 1 1 0 Zinc ribbon domain Chordopox_RPO7 PF05864.7 EMC89453.1 - 0.046 13.8 1.3 0.066 13.3 0.0 1.8 1 1 1 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) LIM PF00412.17 EMC89453.1 - 0.047 13.7 4.2 0.1 12.6 0.1 2.1 1 1 1 2 2 2 0 LIM domain Sgf11 PF08209.6 EMC89453.1 - 0.054 12.8 1.1 0.81 9.0 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_1 PF00130.17 EMC89453.1 - 0.056 13.1 3.1 0.12 12.1 2.2 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_17 PF13534.1 EMC89453.1 - 0.079 13.3 0.6 9.6 6.6 0.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain HypA PF01155.14 EMC89453.1 - 0.097 12.3 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 EMC89453.1 - 0.11 12.6 1.3 0.17 12.0 0.9 1.3 1 1 0 1 1 1 0 CHY zinc finger DNA_RNApol_7kD PF03604.8 EMC89453.1 - 0.17 11.3 1.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.1 EMC89453.1 - 0.18 11.6 3.4 4.8 7.0 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2_6 PF13912.1 EMC89453.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.6 3 0 0 3 3 2 0 C2H2-type zinc finger zf-ISL3 PF14690.1 EMC89453.1 - 0.25 11.4 2.6 6.8 6.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.2 EMC89453.1 - 0.31 10.8 3.1 0.53 10.1 2.1 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMC89453.1 - 0.35 10.4 5.3 5 6.7 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 EMC89453.1 - 0.41 10.8 5.9 8.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.1 EMC89453.1 - 0.52 10.2 2.4 2.8 7.9 1.7 1.9 1 1 0 1 1 1 0 CpXC protein XPA_N PF01286.13 EMC89453.1 - 0.6 9.8 2.8 1.8 8.3 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal C1_3 PF07649.7 EMC89453.1 - 0.7 9.9 3.1 18 5.4 0.2 2.3 2 1 0 2 2 2 0 C1-like domain zf-Mss51 PF13824.1 EMC89453.1 - 2.9 7.7 5.1 4.1 7.3 0.3 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-met PF12874.2 EMC89453.1 - 4.3 7.6 8.0 1.3 9.3 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TFIIS_C PF01096.13 EMC89453.1 - 6 6.5 7.2 3.7 7.2 0.1 2.4 3 0 0 3 3 2 0 Transcription factor S-II (TFIIS) SWIB PF02201.13 EMC89454.1 - 2.2e-25 88.0 0.1 6e-25 86.7 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.20 EMC89455.1 - 3.3e-56 190.3 0.0 4.8e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89455.1 - 4.1e-36 124.3 0.0 6e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC89455.1 - 0.0061 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Methyltransf_26 PF13659.1 EMC89456.1 - 0.0084 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMC89456.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GDPD PF03009.12 EMC89457.1 - 9.9e-62 208.7 0.1 1.7e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.14 EMC89457.1 - 1.4e-09 37.4 0.0 4.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain PI-PLC-X PF00388.14 EMC89457.1 - 0.054 12.9 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF737 PF05300.6 EMC89458.1 - 2.1e-09 37.6 0.6 5.5e-05 23.2 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF737) Sec8_exocyst PF04048.9 EMC89459.1 - 3.3e-34 117.5 5.5 1.1e-33 115.8 2.3 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EMC89459.1 - 0.00013 20.9 7.0 0.00013 20.9 4.8 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 EMC89459.1 - 0.001 19.0 2.2 0.001 19.0 1.5 3.2 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EMC89459.1 - 0.0067 14.9 11.6 0.0042 15.6 4.5 2.1 2 0 0 2 2 2 1 Dor1-like family PEP-utilisers_N PF05524.8 EMC89459.1 - 0.046 13.5 0.4 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Ead_Ea22 PF13935.1 EMC89459.1 - 0.11 12.8 2.3 0.72 10.1 0.6 2.7 2 1 1 3 3 3 0 Ead/Ea22-like protein DASH_Duo1 PF08651.5 EMC89459.1 - 0.22 11.1 7.7 1.7 8.3 0.4 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 Vps51 PF08700.6 EMC89459.1 - 0.94 9.3 8.6 2.6 7.9 0.9 3.0 3 0 0 3 3 3 0 Vps51/Vps67 Cauli_AT PF03233.8 EMC89459.1 - 1.5 8.4 8.6 0.24 11.1 0.5 2.6 3 0 0 3 3 3 0 Aphid transmission protein Nsp1_C PF05064.8 EMC89459.1 - 3 7.5 7.1 15 5.2 0.2 3.2 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF2451 PF10474.4 EMC89460.1 - 0.0022 17.8 0.6 0.01 15.6 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Guanylate_kin PF00625.16 EMC89461.1 - 3.2e-27 95.1 0.0 5.9e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.2 EMC89461.1 - 2.4e-24 84.4 46.6 2.8e-08 33.2 3.3 6.3 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC89461.1 - 1.7e-18 66.1 38.4 6.6e-06 25.7 2.3 5.3 2 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 EMC89461.1 - 2.2e-15 56.6 6.5 1.8e-12 47.1 1.5 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 EMC89461.1 - 4.1e-09 35.2 35.6 0.64 10.2 0.1 10.3 10 1 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 EMC89461.1 - 1.1e-08 34.2 32.8 0.22 11.6 0.1 9.9 9 1 1 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 EMC89461.1 - 7.2e-06 25.3 26.7 0.66 10.4 0.1 9.4 9 1 1 10 10 10 3 Leucine rich repeat MIP-T3 PF10243.4 EMC89462.1 - 7.1e-05 21.4 81.9 8e-05 21.3 56.7 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 UAA PF08449.6 EMC89463.1 - 3.6e-54 183.7 8.2 4.3e-54 183.4 5.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMC89463.1 - 3e-08 33.4 10.9 4e-08 33.0 7.5 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 EMC89463.1 - 0.00076 19.5 7.6 0.0013 18.7 5.3 1.5 1 0 0 1 1 1 1 EamA-like transporter family Kunitz_BPTI PF00014.18 EMC89464.1 - 2.5e-18 66.0 5.5 2.7e-18 65.9 3.8 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Tubulin PF00091.20 EMC89465.1 - 6.7e-71 238.5 0.0 8.8e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMC89465.1 - 1.3e-50 170.6 0.0 2e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMC89465.1 - 0.0041 16.6 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RhoGEF PF00621.15 EMC89466.1 - 2.5e-37 128.5 0.0 4.7e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EMC89466.1 - 3.3e-10 40.0 0.0 7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_5 PF15405.1 EMC89466.1 - 7.8e-09 35.5 0.3 1.4e-07 31.5 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PT PF04886.7 EMC89467.1 - 1.5e-08 33.8 9.0 0.00056 19.1 1.6 4.8 4 1 0 4 4 4 3 PT repeat DUF1220 PF06758.8 EMC89467.1 - 5.4 6.9 9.7 24 4.8 0.1 3.7 2 1 1 3 3 3 0 Repeat of unknown function (DUF1220) EF-hand_1 PF00036.27 EMC89468.1 - 1.2e-38 127.4 10.6 5e-10 37.9 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC89468.1 - 3e-35 120.1 4.4 9.2e-20 70.5 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC89468.1 - 5e-35 118.9 10.8 1.1e-17 63.3 0.7 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMC89468.1 - 6.9e-29 97.1 9.2 9.8e-10 37.4 0.0 4.4 5 0 0 5 5 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC89468.1 - 3.7e-26 89.2 6.4 1.5e-06 27.2 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMC89468.1 - 1e-14 54.1 0.2 5e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC89468.1 - 9.8e-08 31.6 0.4 0.0021 17.7 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC89468.1 - 1.7e-06 28.0 0.1 0.0011 18.9 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EMC89468.1 - 8.1e-06 25.7 1.9 1.6e-05 24.8 0.6 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EMC89468.1 - 4.5e-05 22.9 0.4 0.093 12.3 0.0 3.4 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 EMC89468.1 - 0.00037 20.2 1.0 0.2 11.3 0.1 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Toprim_2 PF13155.1 EMC89468.1 - 0.00069 19.8 0.5 0.33 11.3 0.2 2.3 1 1 1 2 2 2 2 Toprim-like Caleosin PF05042.8 EMC89468.1 - 0.0014 18.2 0.1 0.023 14.2 0.0 2.5 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 EMC89468.1 - 0.039 13.9 0.9 0.32 11.0 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF3349 PF11829.3 EMC89468.1 - 0.043 14.2 0.2 26 5.3 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Hexokinase_2 PF03727.11 EMC89468.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.4 1 1 0 1 1 1 0 Hexokinase DUF533 PF04391.7 EMC89468.1 - 0.15 11.3 0.9 2.7 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) EF-hand_like PF09279.6 EMC89468.1 - 0.18 11.8 1.2 0.37 10.8 0.3 1.9 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Ank PF00023.25 EMC89469.1 - 1.2e-54 179.5 11.7 1e-09 37.7 0.4 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 EMC89469.1 - 5.4e-50 167.6 13.8 2.3e-21 75.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC89469.1 - 3e-35 119.9 5.4 1.1e-09 38.5 0.6 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89469.1 - 4.6e-33 109.9 4.5 1.8e-05 24.5 0.1 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EMC89469.1 - 8.6e-29 98.9 8.9 1e-06 28.8 0.0 5.7 3 1 4 7 7 7 5 Ankyrin repeats (many copies) SOCS_box PF07525.11 EMC89469.1 - 1.7e-12 46.9 0.5 3e-12 46.1 0.3 1.4 1 0 0 1 1 1 1 SOCS box HTH_22 PF13309.1 EMC89470.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 HTH domain GDI PF00996.13 EMC89472.1 - 8.8e-215 713.0 0.2 1e-214 712.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.19 EMC89472.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UvrD-helicase PF00580.16 EMC89473.1 - 3.3e-15 56.2 0.7 1.1e-08 34.8 0.0 3.0 2 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EMC89473.1 - 3e-07 30.2 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EMC89473.1 - 1.1e-06 28.3 0.0 0.0054 16.2 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EMC89473.1 - 6.1e-06 25.6 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 EMC89473.1 - 6.9e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EMC89473.1 - 1.3e-05 25.3 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EMC89473.1 - 9.7e-05 22.0 1.1 0.0052 16.3 0.7 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EMC89473.1 - 0.00039 20.3 1.5 0.3 10.8 0.2 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit TGS PF02824.16 EMC89473.1 - 0.083 12.7 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 TGS domain AAA_17 PF13207.1 EMC89473.1 - 0.089 13.6 0.1 2.8 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sushi PF00084.15 EMC89474.1 - 4e-06 27.0 1.1 6.7e-06 26.3 0.2 1.9 2 0 0 2 2 2 1 Sushi domain (SCR repeat) PT PF04886.7 EMC89475.1 - 2.4e-11 42.7 0.0 0.013 14.8 0.0 4.2 2 1 0 2 2 2 2 PT repeat Adaptin_N PF01602.15 EMC89476.1 - 4.4e-53 180.3 2.0 4.9e-53 180.2 1.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMC89476.1 - 0.039 13.8 1.4 0.43 10.4 0.1 2.4 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Abhydrolase_6 PF12697.2 EMC89477.1 - 6.8e-23 81.7 0.0 7.6e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC89477.1 - 7.1e-08 32.2 0.0 1.3e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC89477.1 - 2.7e-05 23.9 0.0 7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 EMC89477.1 - 0.0045 15.8 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Rhodanese PF00581.15 EMC89478.1 - 3e-13 50.1 0.0 6.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_M14 PF00246.19 EMC89479.1 - 2.9e-83 279.7 0.0 3.5e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMC89479.1 - 3.5e-22 77.8 0.1 8.2e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Phage_min_tail PF05939.8 EMC89479.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Phage minor tail protein Peptidase_M14 PF00246.19 EMC89480.1 - 4.1e-82 275.9 0.0 5.2e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMC89480.1 - 2e-24 85.0 0.1 4.2e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF4636 PF15468.1 EMC89481.1 - 1.6e-05 24.5 2.5 0.00012 21.5 1.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4636) CytochromB561_N PF09786.4 EMC89482.1 - 3.4e-199 663.0 1.5 4.2e-199 662.7 1.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal NPCC PF08058.6 EMC89482.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.8 1 1 0 1 1 1 0 Nuclear pore complex component CoA_binding_3 PF13727.1 EMC89482.1 - 0.096 12.5 0.4 0.24 11.2 0.2 1.7 2 0 0 2 2 2 0 CoA-binding domain Kelch_6 PF13964.1 EMC89483.1 - 1.5e-40 135.7 6.8 2.5e-07 30.5 0.0 6.2 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EMC89483.1 - 2.4e-40 136.0 4.2 1.1e-09 37.8 0.0 6.4 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EMC89483.1 - 1.4e-39 133.3 13.8 1.1e-08 34.4 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 EMC89483.1 - 1.5e-32 111.0 12.3 8.7e-07 28.9 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC89483.1 - 2.3e-31 107.1 7.8 1e-05 25.3 0.0 6.4 6 1 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EMC89483.1 - 3e-27 93.3 12.3 6.2e-06 25.7 0.1 6.8 5 2 1 6 6 6 6 Kelch motif RAG2 PF03089.9 EMC89483.1 - 0.054 12.2 0.0 0.49 9.0 0.0 2.3 2 0 0 2 2 2 0 Recombination activating protein 2 Rsm1 PF08600.5 EMC89484.1 - 1.2e-12 47.4 0.2 1.5e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Rsm1-like UQ_con PF00179.21 EMC89485.1 - 1.1e-36 125.3 0.0 1.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nrf1_DNA-bind PF10491.4 EMC89486.1 - 1.1e-128 426.6 0.3 1.8e-128 425.9 0.2 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.4 EMC89486.1 - 7.8e-07 29.4 5.4 7.8e-07 29.4 3.8 6.1 3 2 2 5 5 5 1 Nrf1 activator activation site binding domain DUF3459 PF11941.3 EMC89486.1 - 0.024 14.7 1.2 0.095 12.8 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) RNF111_N PF15303.1 EMC89486.1 - 0.06 12.8 0.5 0.14 11.6 0.3 1.6 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus AdoHcyase PF05221.12 EMC89487.1 - 1e-104 349.2 0.0 1.2e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EMC89487.1 - 1.5e-55 187.5 0.1 2.4e-55 186.7 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMC89487.1 - 1.2e-05 24.4 0.0 2.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EMC89487.1 - 0.00039 19.8 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EMC89487.1 - 0.0078 16.1 0.2 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 EMC89487.1 - 0.08 12.0 0.2 0.27 10.2 0.1 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EMC89487.1 - 0.086 13.1 0.2 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Ycf34 PF10718.4 EMC89488.1 - 0.04 14.2 11.5 7.6 7.0 0.0 5.4 2 1 4 6 6 6 0 Hypothetical chloroplast protein Ycf34 Tetraspannin PF00335.15 EMC89491.1 - 7.4e-50 169.2 18.7 1.1e-49 168.6 13.0 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF2755 PF10954.3 EMC89491.1 - 3.4 7.4 7.9 1.2 8.8 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) Xpo1 PF08389.7 EMC89492.1 - 2.9e-25 88.9 0.4 4.8e-25 88.1 0.3 1.4 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 EMC89492.1 - 0.0015 18.4 0.3 0.0085 15.9 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF2984 PF11203.3 EMC89494.1 - 2.9 8.0 8.8 13 5.9 0.2 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2984) EF-hand_7 PF13499.1 EMC89495.1 - 4.2e-28 97.2 16.8 3e-10 40.0 0.1 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EMC89495.1 - 4.7e-24 81.8 18.2 3.3e-05 22.8 0.4 7.1 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.1 EMC89495.1 - 3.3e-18 63.8 17.7 0.003 17.3 0.0 7.2 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.1 EMC89495.1 - 7.2e-18 63.0 24.7 4.5e-05 22.6 0.5 7.0 6 1 0 6 6 6 5 EF hand EF-hand_8 PF13833.1 EMC89495.1 - 3.2e-10 39.4 14.1 0.00071 19.1 0.0 5.9 5 1 1 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC89495.1 - 0.063 13.3 10.5 0.91 9.5 0.2 4.0 2 2 2 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EMC89495.1 - 0.1 12.2 2.5 0.93 9.2 0.2 3.2 3 1 0 3 3 3 0 EF hand 7tm_1 PF00001.16 EMC89496.1 - 2.1e-46 158.1 13.1 2.5e-46 157.8 9.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC89496.1 - 1.1e-07 31.3 16.0 2.6e-07 30.0 11.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC89496.1 - 0.0036 16.4 15.0 0.0064 15.6 10.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Cation_efflux PF01545.16 EMC89496.1 - 0.01 14.9 1.0 0.016 14.2 0.7 1.3 1 0 0 1 1 1 0 Cation efflux family 60KD_IMP PF02096.15 EMC89496.1 - 0.04 13.5 0.3 0.04 13.5 0.2 1.5 2 0 0 2 2 2 0 60Kd inner membrane protein Rhodopsin_N PF10413.4 EMC89496.1 - 0.05 13.2 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin HCV_core PF01542.13 EMC89496.1 - 0.075 13.4 0.6 0.3 11.5 0.4 2.0 1 0 0 1 1 1 0 Hepatitis C virus core protein PufQ PF05398.6 EMC89496.1 - 0.084 12.9 1.0 0.2 11.6 0.1 2.1 2 0 0 2 2 2 0 PufQ cytochrome subunit BHD_1 PF10403.4 EMC89503.1 - 0.01 15.3 2.7 3.5 7.2 0.0 4.1 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 1 GDE_C PF06202.9 EMC89503.1 - 0.21 10.2 0.1 0.29 9.7 0.1 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase RRM_1 PF00076.17 EMC89507.1 - 3.4e-37 125.9 0.0 6.7e-16 57.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89507.1 - 5.6e-33 112.7 0.1 5.1e-11 42.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89507.1 - 7.8e-22 76.8 0.0 6.6e-12 45.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.5 EMC89507.1 - 1.6e-05 24.1 17.4 2.1e-05 23.8 12.1 1.1 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.9 EMC89507.1 - 0.00014 20.0 14.9 0.00018 19.6 10.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Ycf1 PF05758.7 EMC89507.1 - 0.00097 16.9 6.4 0.0012 16.7 4.4 1.0 1 0 0 1 1 1 1 Ycf1 Nop14 PF04147.7 EMC89507.1 - 0.0043 15.0 32.2 0.0058 14.6 22.3 1.1 1 0 0 1 1 1 1 Nop14-like family Spore_coat_CotO PF14153.1 EMC89507.1 - 0.014 14.7 17.0 0.022 14.2 11.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Nup35_RRM_2 PF14605.1 EMC89507.1 - 0.17 11.6 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SAPS PF04499.10 EMC89507.1 - 0.18 10.4 8.0 0.24 9.9 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 EMC89507.1 - 0.23 9.9 36.6 0.33 9.3 25.4 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EMC89507.1 - 0.24 10.6 32.3 0.37 10.0 22.4 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 EMC89507.1 - 0.39 8.3 1.9 0.5 7.9 1.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 EMC89507.1 - 1.1 9.2 18.3 2.1 8.3 12.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2146 PF10220.4 EMC89507.1 - 4.3 5.1 9.2 5.8 4.7 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) U79_P34 PF03064.11 EMC89507.1 - 5 6.5 20.4 8.2 5.8 14.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3530 PF12048.3 EMC89507.1 - 5.4 5.9 7.4 9.4 5.1 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF1510 PF07423.6 EMC89507.1 - 7.8 5.8 32.2 12 5.1 22.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SNase PF00565.12 EMC89509.1 - 2.1e-55 185.5 0.1 5.2e-16 58.8 0.0 4.7 4 1 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.19 EMC89509.1 - 1.2e-26 92.8 0.0 2.7e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Tecti-min-caps PF09300.5 EMC89509.1 - 0.14 11.9 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Tectiviridae, minor capsid PAX PF00292.13 EMC89510.1 - 8.9e-51 170.8 0.2 1.3e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 EMC89510.1 - 7.2e-20 70.3 2.8 1.6e-19 69.2 2.0 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EMC89510.1 - 2.5e-05 23.7 1.9 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EMC89510.1 - 0.00026 21.1 2.9 0.0017 18.4 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix Homeobox_KN PF05920.6 EMC89510.1 - 0.0034 17.0 0.2 0.0093 15.6 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_28 PF13518.1 EMC89510.1 - 0.038 14.0 0.8 0.067 13.2 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.1 EMC89510.1 - 0.069 13.9 0.1 0.66 10.8 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Fe_dep_repress PF01325.14 EMC89510.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Arf PF00025.16 EMC89511.1 - 3.4e-72 241.3 0.2 3.8e-72 241.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC89511.1 - 4.1e-13 48.9 0.0 4.9e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMC89511.1 - 4.7e-13 48.8 0.0 5.1e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMC89511.1 - 6.3e-11 41.8 0.0 7.1e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC89511.1 - 7.1e-10 38.1 0.4 1.8e-09 36.8 0.2 1.6 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 EMC89511.1 - 5.1e-08 33.4 0.0 7.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMC89511.1 - 2.3e-05 24.3 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC89511.1 - 0.005 16.2 0.4 0.013 14.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF3887 PF13026.1 EMC89511.1 - 0.13 12.6 0.1 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) GRIP PF01465.15 EMC89512.1 - 6.6e-17 60.7 0.0 1.8e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 GRIP domain SPA PF08616.5 EMC89515.1 - 4.1e-07 29.6 0.0 2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 EMC89515.1 - 1.3e-05 24.9 1.3 2.9e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 EMC89515.1 - 0.00051 18.6 0.0 0.00096 17.7 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.1 EMC89515.1 - 0.75 10.0 3.9 0.35 11.1 0.2 2.0 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein SAPS PF04499.10 EMC89516.1 - 4.3e-77 259.7 15.1 1.8e-59 201.6 0.9 4.0 4 0 0 4 4 4 3 SIT4 phosphatase-associated protein Arm PF00514.18 EMC89516.1 - 0.0022 17.7 0.1 1.2 9.0 0.0 3.3 2 1 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC89516.1 - 0.068 13.4 1.0 0.28 11.4 0.2 2.4 2 1 1 3 3 3 0 HEAT repeats Myotub-related PF06602.9 EMC89517.1 - 1.7e-47 161.9 3.9 1.8e-47 161.8 2.7 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Myotub-related PF06602.9 EMC89518.1 - 7.5e-29 100.5 0.0 8.7e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DUF1032 PF06278.6 EMC89519.1 - 1.7e-102 343.7 2.9 1.3e-99 334.2 2.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1032) Collagen PF01391.13 EMC89521.1 - 1.8e-06 27.4 61.7 0.28 10.7 9.4 4.4 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Lustrin_cystein PF14625.1 EMC89521.1 - 0.0076 16.3 112.8 2.9 8.0 2.3 11.7 1 1 10 11 11 11 11 Lustrin, cysteine-rich repeated domain Drf_FH1 PF06346.7 EMC89522.1 - 7.2e-09 35.3 23.2 0.00023 20.7 7.0 2.5 1 1 1 2 2 2 2 Formin Homology Region 1 Choline_kinase PF01633.15 EMC89523.1 - 3.6e-55 186.8 0.4 2.3e-54 184.1 0.1 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EMC89523.1 - 8.2e-11 42.0 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMC89523.1 - 1.1e-05 24.8 0.1 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase SH3_9 PF14604.1 EMC89524.1 - 2.2e-12 46.3 0.1 6.2e-12 44.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC89524.1 - 9.4e-07 28.1 0.0 2.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Topo-VIb_trans PF09239.6 EMC89525.1 - 0.42 10.1 15.7 8.8 5.8 1.3 3.6 1 1 4 5 5 5 0 Topoisomerase VI B subunit, transducer Ank_4 PF13637.1 EMC89526.1 - 8.8e-16 57.9 1.3 5.7e-08 33.0 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC89526.1 - 3e-14 53.0 0.6 6.9e-10 39.1 0.5 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC89526.1 - 2.4e-13 49.8 4.1 1.1e-05 25.4 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMC89526.1 - 2.3e-12 46.0 5.1 0.0059 16.3 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EMC89526.1 - 2.5e-08 33.3 4.3 0.0045 17.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat DUF2730 PF10805.3 EMC89528.1 - 1.1e-20 73.3 0.3 50 3.6 0.0 16.3 1 1 18 20 20 20 20 Protein of unknown function (DUF2730) Trypsin PF00089.21 EMC89529.1 - 4.2e-70 235.7 3.8 4.7e-70 235.6 2.6 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC89529.1 - 0.0001 21.6 1.2 0.00016 21.1 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC89529.1 - 0.0011 18.8 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 EMC89529.1 - 0.0024 17.2 2.2 0.61 9.3 0.0 2.6 1 1 0 2 2 2 2 Domain of unknown function (DUF316) Sulfatase_C PF14707.1 EMC89530.1 - 1.2e-30 106.5 0.0 1.3e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Sulfatase PF00884.18 EMC89531.1 - 1.5e-12 47.3 0.0 1.6e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMC89531.1 - 2.4e-07 30.4 0.0 2.5e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 EMC89531.1 - 0.0014 17.5 0.0 0.0015 17.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Trypsin PF00089.21 EMC89532.1 - 3.1e-68 229.6 4.5 3.4e-68 229.5 3.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC89532.1 - 3.1e-05 23.3 1.0 4.7e-05 22.8 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC89532.1 - 3.8e-05 23.6 0.0 7.3e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 EMC89532.1 - 0.00047 19.5 0.2 0.46 9.7 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF316) Ras PF00071.17 EMC89533.1 - 6.1e-29 100.4 0.0 7.4e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC89533.1 - 1.3e-12 48.2 0.0 2.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC89533.1 - 4.4e-07 29.3 0.0 5.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC89533.1 - 3.5e-06 26.5 0.0 6.7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC89533.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMC89533.1 - 0.029 13.8 0.1 0.038 13.5 0.1 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein NDK PF00334.14 EMC89534.1 - 7.4e-18 64.6 0.0 9.3e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase 7tm_4 PF13853.1 EMC89536.1 - 2.2e-38 131.2 4.2 2.2e-38 131.2 2.9 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC89536.1 - 2.6e-32 111.9 12.7 3.4e-32 111.5 8.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC89536.1 - 0.00033 19.9 2.6 0.00048 19.3 1.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC89536.1 - 0.033 13.3 4.7 0.049 12.7 2.7 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF3112 PF11309.3 EMC89536.1 - 3.4 7.4 7.2 6.7 6.4 4.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3112) HS1_rep PF02218.10 EMC89537.1 - 1.8e-56 187.7 46.2 1.5e-17 63.1 3.6 5.8 7 0 0 7 7 7 4 Repeat in HS1/Cortactin SH3_9 PF14604.1 EMC89537.1 - 9.7e-18 63.4 0.2 2.4e-17 62.2 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC89537.1 - 4.6e-16 57.9 0.2 1e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMC89537.1 - 8.5e-09 34.7 0.0 2.4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.1 EMC89537.1 - 0.13 12.4 0.1 1.1e+02 2.9 0.0 3.8 2 2 2 4 4 4 0 TMEM210 family Collagen PF01391.13 EMC89538.1 - 4.2e-07 29.4 11.9 0.0028 17.1 1.7 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Bactofilin PF04519.8 EMC89538.1 - 0.00049 20.0 14.3 0.72 9.8 9.9 2.7 1 1 0 1 1 1 1 Polymer-forming cytoskeletal Chorion_1 PF01723.11 EMC89538.1 - 0.026 14.4 5.1 2.7 7.8 0.2 2.6 1 1 2 3 3 3 0 Chorion protein CRAM_rpt PF07016.6 EMC89538.1 - 0.044 13.1 2.5 2.3 7.6 0.1 3.6 2 2 1 3 3 3 0 Cysteine-rich acidic integral membrane protein precursor EF-hand_1 PF00036.27 EMC89539.1 - 8.8e-24 80.9 13.5 2e-07 29.8 0.1 5.2 4 1 1 5 5 5 3 EF hand EF-hand_6 PF13405.1 EMC89539.1 - 4.5e-22 75.8 4.4 7.1e-06 25.4 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EMC89539.1 - 8.1e-22 77.1 3.0 5.5e-14 52.0 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC89539.1 - 2e-21 75.3 5.2 4.6e-11 42.1 0.0 3.2 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC89539.1 - 3.1e-17 61.0 10.7 6.2e-06 25.3 0.0 4.7 5 1 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 EMC89539.1 - 7.3e-09 35.6 0.0 2.1e-05 24.4 0.0 2.4 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC89539.1 - 1.3e-05 24.9 2.2 0.51 10.1 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMC89539.1 - 0.0056 16.3 1.0 6.1 6.5 0.0 3.6 4 0 0 4 4 4 1 EF hand VCBS PF13517.1 EMC89539.1 - 0.11 12.8 0.1 20 5.6 0.0 3.0 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Acetyltransf_1 PF00583.19 EMC89541.1 - 4e-14 52.4 0.1 5.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMC89541.1 - 1.6e-08 34.1 0.0 2.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EMC89541.1 - 1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC89541.1 - 0.00011 22.3 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMC89541.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PACT_coil_coil PF10495.4 EMC89542.1 - 1.5e-29 101.7 0.1 2.3e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF3138 PF11336.3 EMC89543.1 - 0.15 10.1 1.1 0.16 10.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) pRN1_helical PF13010.1 EMC89543.1 - 0.18 11.4 5.0 0.18 11.4 1.7 1.9 1 1 1 2 2 2 0 Primase helical domain DUF3496 PF12001.3 EMC89543.1 - 4.9 7.4 12.1 0.62 10.3 2.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) DUF445 PF04286.7 EMC89543.1 - 7.3 6.0 13.1 9.4 5.6 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SAE2 PF08573.5 EMC89543.1 - 9.9 6.9 7.6 67 4.2 5.3 2.2 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4587 PF15248.1 EMC89544.1 - 3e-31 107.8 12.7 3e-31 107.8 8.8 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4587) APH PF01636.18 EMC89544.1 - 1.4 8.6 8.5 6.2 6.4 5.8 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family IncA PF04156.9 EMC89544.1 - 4.7 6.7 7.2 6.9 6.2 5.0 1.2 1 0 0 1 1 1 0 IncA protein FAD_binding_3 PF01494.14 EMC89545.1 - 2.2e-19 69.7 0.0 4.6e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMC89545.1 - 2.7e-06 26.5 0.0 3.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMC89545.1 - 2.2e-05 24.3 0.5 8.2e-05 22.5 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMC89545.1 - 0.00021 20.2 0.1 0.11 11.2 0.0 2.4 2 1 0 2 2 2 2 Squalene epoxidase 3HCDH_N PF02737.13 EMC89545.1 - 0.001 18.7 0.2 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMC89545.1 - 0.0062 16.9 0.6 0.013 15.9 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMC89545.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EMC89545.1 - 0.14 11.4 0.2 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Integrin_beta PF00362.13 EMC89546.1 - 2.1e-175 583.7 0.1 3.8e-175 582.8 0.0 1.4 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 EMC89546.1 - 8.3e-21 73.1 0.7 1.7e-20 72.1 0.5 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 EMC89546.1 - 1.9e-17 63.4 12.0 1.9e-17 63.4 8.3 4.1 4 0 0 4 4 4 1 Integrin beta tail domain hEGF PF12661.2 EMC89546.1 - 0.003 17.5 1.8 0.003 17.5 1.2 6.5 9 0 0 9 9 9 1 Human growth factor-like EGF EGF_2 PF07974.8 EMC89546.1 - 0.009 16.1 7.7 0.009 16.1 5.3 7.5 6 2 0 6 6 6 3 EGF-like domain Syndecan PF01034.15 EMC89546.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain SLX9 PF15341.1 EMC89547.1 - 2.3e-20 73.2 1.6 2.6e-20 73.0 1.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF4061 PF13270.1 EMC89547.1 - 0.065 13.3 1.0 4 7.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Keratin PF02422.11 EMC89549.1 - 3.8e-30 103.7 16.3 4.5e-30 103.4 11.3 1.1 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC89549.1 - 0.014 15.4 8.8 0.018 15.0 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) zf-Tim10_DDP PF02953.10 EMC89549.1 - 0.16 11.3 0.6 0.27 10.5 0.4 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Keratin PF02422.11 EMC89550.1 - 7.2e-29 99.6 15.3 8.7e-29 99.3 10.6 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC89550.1 - 0.1 12.6 10.3 0.14 12.2 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) YrhC PF14143.1 EMC89551.1 - 1.8 8.5 5.7 11 5.9 0.2 4.1 2 1 2 4 4 4 0 YrhC-like protein BAR PF03114.13 EMC89552.1 - 2e-71 240.1 8.2 2.3e-71 239.9 5.7 1.0 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EMC89552.1 - 3.3e-15 55.1 0.2 1.4e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMC89552.1 - 8.5e-15 54.0 0.1 1.6e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC89552.1 - 1.9e-13 49.6 0.0 4e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.4 EMC89552.1 - 1.2e-08 34.2 4.0 6.8e-08 31.7 1.9 2.0 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Exonuc_VII_L PF02601.10 EMC89552.1 - 0.14 11.3 3.4 0.2 10.8 2.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FH2 PF02181.18 EMC89552.1 - 0.22 10.3 6.9 0.12 11.2 2.9 1.9 2 0 0 2 2 2 0 Formin Homology 2 Domain Tropomyosin_1 PF12718.2 EMC89553.1 - 6.2e-06 26.1 32.8 6.2e-06 26.1 22.7 3.3 1 1 1 3 3 2 1 Tropomyosin like IncA PF04156.9 EMC89553.1 - 1.1e-05 25.1 28.1 1.1e-05 25.1 19.5 3.3 1 1 2 3 3 2 1 IncA protein Baculo_PEP_C PF04513.7 EMC89553.1 - 0.00017 21.4 18.5 0.001 18.9 3.6 2.6 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 EMC89553.1 - 0.00031 20.4 8.3 0.00031 20.4 5.8 6.4 3 2 2 5 5 4 2 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EMC89553.1 - 0.0011 18.2 18.6 0.061 12.4 1.2 3.0 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EMC89553.1 - 0.0037 17.3 36.1 0.056 13.5 6.9 3.5 1 1 1 3 3 3 2 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 EMC89553.1 - 0.0075 16.0 25.7 0.0075 16.0 17.8 4.1 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 EMC89553.1 - 0.013 15.3 19.7 0.63 9.9 1.9 4.2 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.1 EMC89553.1 - 0.014 15.4 12.7 0.014 15.4 8.8 4.1 1 1 3 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit PGA_cap PF09587.5 EMC89553.1 - 0.061 12.6 0.1 0.16 11.2 0.0 1.8 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap MscS_porin PF12795.2 EMC89553.1 - 0.15 11.3 46.5 1.1 8.5 7.5 3.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF641 PF04859.7 EMC89553.1 - 0.19 11.4 34.9 0.49 10.1 5.0 4.7 1 1 3 5 5 5 0 Plant protein of unknown function (DUF641) Spc7 PF08317.6 EMC89553.1 - 0.39 9.3 48.0 0.015 13.9 19.7 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein IFT57 PF10498.4 EMC89553.1 - 1 8.0 45.6 0.8 8.3 8.7 3.4 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 ATG16 PF08614.6 EMC89553.1 - 1 9.1 50.4 0.11 12.3 7.5 4.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF1192 PF06698.6 EMC89553.1 - 1.5 8.6 10.3 0.47 10.3 1.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) HCR PF07111.7 EMC89553.1 - 2.1 6.2 43.8 0.95 7.3 1.6 2.2 1 1 1 2 2 2 0 Alpha helical coiled-coil rod protein (HCR) DUF1664 PF07889.7 EMC89553.1 - 2.2 8.1 28.6 0.24 11.2 1.9 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EMC89553.1 - 2.4 8.4 19.0 2.1 8.6 0.7 4.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EMC89553.1 - 2.7 6.3 43.7 0.097 11.1 14.3 2.5 1 1 1 2 2 2 0 AAA domain DUF745 PF05335.8 EMC89553.1 - 3.4 7.1 37.9 0.2 11.1 4.1 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF745) Atg14 PF10186.4 EMC89553.1 - 3.5 6.5 48.9 0.051 12.5 14.5 3.0 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DIT1_PvcA PF05141.7 EMC89553.1 - 4.6 6.4 21.8 0.31 10.3 5.0 2.5 1 1 1 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein DUF2968 PF11180.3 EMC89553.1 - 8.5 5.6 33.3 0.24 10.7 4.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) HisKA_3 PF07730.8 EMC89553.1 - 8.8 6.7 11.3 13 6.2 0.9 4.0 3 0 0 3 3 3 0 Histidine kinase zf-C2H2_4 PF13894.1 EMC89554.1 - 6.8e-12 44.8 29.6 0.0097 16.1 0.7 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.21 EMC89554.1 - 6.2e-09 35.6 33.1 0.0036 17.5 1.0 6.9 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.2 EMC89554.1 - 2.2e-07 30.8 21.1 0.0068 16.5 0.1 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC89554.1 - 0.013 15.6 20.9 0.68 10.1 0.4 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Arg_repressor PF01316.16 EMC89554.1 - 0.044 13.3 0.0 0.17 11.4 0.0 2.0 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Yae1_N PF09811.4 EMC89555.1 - 3.6e-09 35.9 43.8 0.034 13.6 14.3 4.5 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Yae1_N PF09811.4 EMC89556.1 - 5.9e-09 35.3 62.9 0.0035 16.8 3.7 5.3 2 2 2 4 4 4 3 Essential protein Yae1, N terminal LEDGF PF11467.3 EMC89557.1 - 6.5e-40 135.1 6.2 6.5e-40 135.1 4.3 2.5 3 0 0 3 3 3 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.12 EMC89557.1 - 8.7e-18 64.3 0.1 8.7e-18 64.3 0.1 3.7 3 1 0 3 3 3 1 PWWP domain DUF3744 PF12558.3 EMC89557.1 - 9.8 6.7 8.5 0.73 10.3 0.4 2.9 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter zf-SNAP50_C PF12251.3 EMC89558.1 - 1e-69 233.8 3.6 1.3e-69 233.4 2.5 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF3808 PF10300.4 EMC89559.1 - 1.2e-163 545.1 10.4 1.4e-163 544.8 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EMC89559.1 - 2.7e-11 43.2 8.3 4.3e-08 32.9 0.1 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC89559.1 - 8.5e-09 34.6 14.1 0.056 13.3 0.4 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMC89559.1 - 1.1e-06 28.1 10.1 0.0034 16.9 0.1 4.7 3 1 2 5 5 5 3 TPR repeat TPR_1 PF00515.23 EMC89559.1 - 0.00014 21.2 11.3 0.1 12.2 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC89559.1 - 0.00027 21.5 4.3 1.4 9.6 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMC89559.1 - 0.0018 18.5 15.4 0.24 11.9 0.4 6.9 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC89559.1 - 0.0048 16.5 9.8 0.29 10.9 0.3 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC89559.1 - 0.0057 16.3 5.6 0.37 10.6 0.2 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC89559.1 - 0.0082 16.6 2.1 42 5.1 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat B1 PF02246.10 EMC89559.1 - 0.025 14.3 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein L b1 domain TPR_19 PF14559.1 EMC89559.1 - 0.11 12.8 10.3 0.11 12.8 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Calx-beta PF03160.9 EMC89560.1 - 4.3e-11 42.6 0.1 1.7e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 Calx-beta domain Herpes_UL45 PF05473.7 EMC89560.1 - 0.15 11.4 0.1 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 UL45 protein DAN PF03045.10 EMC89561.1 - 5.5e-35 119.4 8.9 1e-34 118.5 6.2 1.4 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 EMC89561.1 - 0.00074 19.5 6.6 0.0012 18.9 4.6 1.2 1 0 0 1 1 1 1 Cystine-knot domain Sclerostin PF05463.6 EMC89561.1 - 0.00087 18.8 2.5 0.0029 17.1 1.7 1.7 1 1 0 1 1 1 1 Sclerostin (SOST) DUF1661 PF07877.6 EMC89561.1 - 0.043 13.3 0.2 0.17 11.4 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) zf-DHHC PF01529.15 EMC89562.1 - 2.5e-32 111.6 11.0 2.5e-32 111.6 7.6 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EMC89562.1 - 0.051 13.3 1.4 0.099 12.4 1.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily MH1 PF03165.11 EMC89563.1 - 1.2e-12 47.6 1.3 2.5e-12 46.6 0.9 1.5 1 1 0 1 1 1 1 MH1 domain CTF_NFI PF00859.13 EMC89564.1 - 4.3e-110 368.1 29.8 5.8e-110 367.6 20.7 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region Sema PF01403.14 EMC89566.1 - 4.2e-42 144.1 0.0 4.6e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Sema domain Pox_E10 PF04805.7 EMC89566.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 E10-like protein conserved region IL17 PF06083.6 EMC89567.1 - 2.4e-30 104.3 0.6 5e-30 103.3 0.2 1.7 2 0 0 2 2 2 1 Interleukin-17 IL17 PF06083.6 EMC89568.1 - 1.8e-29 101.6 0.0 2.9e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Interleukin-17 HlyIII PF03006.15 EMC89569.1 - 1.8e-45 155.0 16.7 2.9e-45 154.4 11.5 1.3 1 0 0 1 1 1 1 Haemolysin-III related DUF1126 PF06565.7 EMC89570.1 - 1.2e-43 146.2 3.8 1.9e-15 56.0 0.1 4.2 4 0 0 4 4 4 3 Repeat of unknown function (DUF1126) S_layer_N PF05123.7 EMC89570.1 - 0.28 10.7 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 S-layer like family, N-terminal region TRAM1 PF08390.6 EMC89572.1 - 2.1e-21 75.1 0.4 2.1e-21 75.1 0.3 2.1 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 EMC89572.1 - 6.9e-19 68.1 16.6 1.2e-18 67.4 11.5 1.4 1 0 0 1 1 1 1 TLC domain Cytochrom_B558a PF05038.8 EMC89572.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF3112 PF11309.3 EMC89572.1 - 0.16 11.7 5.0 3.8 7.2 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) AKAP7_RIRII_bdg PF10470.4 EMC89575.1 - 1.1e-05 25.1 2.0 1.2e-05 25.0 1.4 1.1 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein BTB PF00651.26 EMC89576.1 - 3e-28 98.0 0.9 5.7e-28 97.1 0.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 EMC89576.1 - 9.1e-25 85.4 37.6 1.8e-05 24.7 0.1 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC89576.1 - 2.2e-23 81.3 47.7 2.1e-06 27.7 2.6 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC89576.1 - 2.5e-19 68.1 27.6 0.0013 18.9 0.1 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89576.1 - 3.2e-15 55.7 23.4 0.00093 19.2 0.2 5.8 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC89576.1 - 1.1e-13 50.8 21.5 0.0021 18.1 0.4 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type C1_4 PF07975.7 EMC89576.1 - 0.02 14.8 15.7 4.6 7.3 2.3 4.1 2 1 1 3 3 3 0 TFIIH C1-like domain LIM PF00412.17 EMC89576.1 - 0.022 14.8 19.4 2.1 8.4 2.5 4.3 2 2 2 4 4 4 0 LIM domain zf-C2H2_6 PF13912.1 EMC89576.1 - 0.027 14.3 9.7 0.62 10.0 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger BTB_2 PF02214.17 EMC89576.1 - 0.05 13.8 0.3 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain zf-C2HC_2 PF13913.1 EMC89576.1 - 0.065 12.9 5.1 1.5 8.5 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Elf1 PF05129.8 EMC89576.1 - 1.8 8.3 16.8 0.31 10.7 0.5 3.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EMC89576.1 - 2.1 8.5 24.8 1.8 8.7 4.1 3.8 3 2 0 3 3 3 0 CHY zinc finger zf-trcl PF13451.1 EMC89576.1 - 3.3 7.4 12.7 38 4.0 0.1 4.9 5 0 0 5 5 5 0 Probable zinc-binding domain FYDLN_acid PF09538.5 EMC89576.1 - 4.9 7.7 17.8 34 5.0 0.0 4.9 3 2 1 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF678 PF05077.7 EMC89576.1 - 6.5 6.8 8.9 26 4.9 0.5 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF678) RIG-I_C-RD PF11648.3 EMC89576.1 - 9.6 6.0 12.8 0.44 10.4 0.1 3.9 2 1 1 3 3 3 0 C-terminal domain of RIG-I 4_1_CTD PF05902.8 EMC89577.1 - 5.6e-57 190.7 13.6 5.6e-57 190.7 9.4 2.3 2 0 0 2 2 2 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 EMC89577.1 - 2.1e-26 91.3 2.7 5.2e-26 90.0 1.9 1.7 1 0 0 1 1 1 1 SAB domain FERM_N PF09379.5 EMC89577.1 - 6.2e-23 80.6 0.2 8.8e-22 76.9 0.0 2.8 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.5 EMC89577.1 - 7.3e-23 80.6 0.0 1.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 EMC89577.1 - 1.1e-20 74.0 0.0 1.1e-20 74.0 0.0 2.8 3 0 0 3 3 3 1 FERM central domain FA PF08736.6 EMC89577.1 - 1.1e-18 66.7 6.4 2.9e-18 65.4 4.4 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) DUF3184 PF11380.3 EMC89577.1 - 0.043 11.7 0.8 0.073 11.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) 7tm_4 PF13853.1 EMC89578.1 - 2.1e-54 183.2 5.9 2.4e-54 183.0 4.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC89578.1 - 6.3e-06 25.5 3.0 8e-06 25.1 2.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AMP-binding PF00501.23 EMC89580.1 - 3.2e-10 38.9 0.3 3.4e-10 38.8 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme p450 PF00067.17 EMC89581.1 - 2.9e-37 128.2 2.3 2.9e-21 75.5 0.1 3.1 1 1 2 3 3 3 3 Cytochrome P450 DUF1510 PF07423.6 EMC89582.1 - 0.25 10.6 31.0 0.34 10.2 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med12-LCEWAV PF12145.3 EMC89582.1 - 0.64 8.4 7.7 0.87 8.0 5.4 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain DUF4045 PF13254.1 EMC89582.1 - 0.64 9.2 8.0 0.8 8.9 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Daxx PF03344.10 EMC89582.1 - 7.5 4.9 45.0 11 4.3 31.2 1.1 1 0 0 1 1 1 0 Daxx Family SpoIIIAH PF12685.2 EMC89582.1 - 7.8 5.9 16.3 11 5.4 11.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein V-set PF07686.12 EMC89583.1 - 2.6e-10 40.1 1.9 3.3e-10 39.8 1.3 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC89583.1 - 0.00082 19.4 1.1 0.0011 19.0 0.8 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC89583.1 - 0.008 16.0 0.4 0.012 15.4 0.3 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC89583.1 - 0.16 12.4 1.5 0.21 12.1 1.1 1.3 1 1 0 1 1 1 0 Immunoglobulin domain 7tm_4 PF13853.1 EMC89584.1 - 1e-34 119.3 16.1 1e-34 119.3 11.1 3.2 3 1 1 4 4 4 2 Olfactory receptor 7tm_1 PF00001.16 EMC89584.1 - 1e-22 80.5 17.8 1.5e-22 79.9 12.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC89585.1 - 2e-24 86.1 8.7 2e-24 86.1 6.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 EMC89585.1 - 5.5e-07 29.4 1.9 5.5e-07 29.4 1.3 2.9 2 1 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 EMC89585.1 - 6.7e-05 22.1 13.8 8.9e-05 21.7 9.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3814 PF12769.2 EMC89585.1 - 0.011 15.8 3.3 0.026 14.6 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) Keratin PF02422.11 EMC89586.1 - 3.3e-27 94.3 16.9 3.6e-27 94.1 11.7 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC89586.1 - 1.4 8.9 8.4 1.8 8.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 EMC89587.1 - 3e-30 104.0 16.0 3.3e-30 103.9 11.1 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 EMC89587.1 - 0.036 14.0 9.4 0.045 13.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) zf-Tim10_DDP PF02953.10 EMC89587.1 - 0.11 11.7 0.4 0.17 11.1 0.3 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger UQ_con PF00179.21 EMC89588.1 - 1.2e-18 66.8 0.0 1.3e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC89588.1 - 0.0093 15.8 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Voltage_CLC PF00654.15 EMC89589.1 - 2.3e-23 82.8 8.7 2.6e-23 82.6 6.0 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel MtrG PF04210.8 EMC89589.1 - 0.12 12.0 1.6 0.22 11.2 1.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G zf-H2C2_2 PF13465.1 EMC89590.1 - 1.7e-25 87.9 28.0 5.7e-09 35.8 0.2 5.7 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89590.1 - 3.5e-25 86.7 42.2 4.2e-06 26.7 0.3 5.6 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89590.1 - 1.3e-17 62.7 34.8 0.00039 20.5 1.4 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89590.1 - 1.2e-14 53.9 26.9 0.00023 21.2 0.2 6.2 5 1 1 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC89590.1 - 1.2e-13 50.4 31.0 0.00015 21.4 2.9 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-Di19 PF05605.7 EMC89590.1 - 3.4e-07 30.2 18.0 0.0062 16.6 2.7 3.7 3 1 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EMC89590.1 - 7.3e-07 29.1 26.7 0.0055 16.8 0.3 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-BED PF02892.10 EMC89590.1 - 5.2e-06 26.1 26.5 0.18 11.6 1.4 5.5 3 1 2 5 5 5 4 BED zinc finger Elf1 PF05129.8 EMC89590.1 - 0.00031 20.3 16.0 0.023 14.3 0.5 3.2 2 1 1 3 3 3 2 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 EMC89590.1 - 0.0013 18.2 17.1 0.49 10.1 0.3 5.4 5 0 0 5 5 5 3 zinc-finger of a C2HC-type Rpr2 PF04032.11 EMC89590.1 - 0.0032 17.2 12.5 0.057 13.2 0.4 2.4 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_2 PF12756.2 EMC89590.1 - 0.0045 17.0 21.4 1.7 8.7 0.1 5.1 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EMC89590.1 - 0.3 10.5 17.4 2.6 7.5 0.9 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 EMC89590.1 - 0.32 11.0 25.5 0.79 9.7 1.6 4.8 4 1 0 4 4 4 0 Zinc ribbon domain Trm112p PF03966.11 EMC89590.1 - 0.32 11.3 2.1 10 6.5 0.4 3.5 3 1 0 3 3 3 0 Trm112p-like protein zf-HYPF PF07503.7 EMC89590.1 - 1.2 8.5 11.2 2.8 7.4 0.6 3.2 2 1 0 2 2 2 0 HypF finger Zn_Tnp_IS1595 PF12760.2 EMC89590.1 - 2.3 8.0 26.6 0.063 13.0 4.2 4.0 2 2 2 4 4 4 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EMC89590.1 - 3.1 7.8 10.6 0.53 10.3 0.2 4.0 4 0 0 4 4 4 0 zinc-finger zf-CHY PF05495.7 EMC89590.1 - 4.9 7.3 26.0 2.1 8.5 5.0 2.6 2 1 0 2 2 2 0 CHY zinc finger zf-AN1 PF01428.11 EMC89590.1 - 8.4 6.3 24.7 11 6.0 0.1 5.2 5 0 0 5 5 5 0 AN1-like Zinc finger zinc_ribbon_5 PF13719.1 EMC89590.1 - 9.2 5.9 18.1 2.7 7.6 0.2 4.7 5 0 0 5 5 5 0 zinc-ribbon domain XendoU PF09412.5 EMC89592.1 - 1.5e-88 296.3 0.3 1.7e-88 296.1 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.1 EMC89592.1 - 0.0017 18.1 0.2 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial EndoU nuclease DUF643 PF04867.7 EMC89592.1 - 0.086 13.2 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF643) zf-H2C2_2 PF13465.1 EMC89594.1 - 4.7e-14 51.8 9.2 4.9e-08 32.8 2.4 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89594.1 - 6.2e-13 48.2 27.0 2.4e-05 24.3 0.6 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC89594.1 - 1.3e-09 37.6 25.4 0.00011 22.2 0.9 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC89594.1 - 0.0084 16.2 5.2 1.8 8.8 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 EMC89594.1 - 0.016 14.6 0.8 0.58 9.6 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_6 PF13912.1 EMC89594.1 - 0.032 14.1 8.4 0.39 10.6 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.27 EMC89595.1 - 1.5e-09 37.4 8.7 7.4e-07 28.8 0.0 4.2 4 1 1 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.7 EMC89595.1 - 0.00056 19.5 1.1 0.32 10.6 0.1 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF4613 PF15390.1 EMC89595.1 - 0.0018 16.5 3.2 0.18 9.9 0.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4613) eIF2A PF08662.6 EMC89595.1 - 0.0021 17.7 0.0 0.0052 16.5 0.0 1.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EMC89595.1 - 0.037 13.4 1.6 0.15 11.4 0.8 1.6 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Hormone_recep PF00104.25 EMC89596.1 - 1.9e-30 105.5 2.6 3.1e-30 104.8 1.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 EMC89596.1 - 6.2e-29 100.0 15.8 1.1e-28 99.2 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF3782 PF12644.2 EMC89596.1 - 0.52 10.1 2.4 1.4 8.7 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) DUF1356 PF07092.7 EMC89597.1 - 6.7e-98 326.6 4.9 7.4e-98 326.4 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.8 EMC89597.1 - 0.0021 18.3 0.3 0.0035 17.7 0.2 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein Amnionless PF14828.1 EMC89597.1 - 0.036 12.5 0.1 0.042 12.3 0.1 1.1 1 0 0 1 1 1 0 Amnionless Peptidase_A3 PF02160.10 EMC89597.1 - 0.045 13.3 0.3 0.064 12.8 0.2 1.1 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Ank_2 PF12796.2 EMC89598.1 - 2.8e-38 130.1 1.1 2.8e-22 78.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC89598.1 - 6.9e-36 120.2 3.0 6.2e-10 38.3 0.0 5.3 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMC89598.1 - 2.8e-34 116.8 3.6 2.1e-11 44.0 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC89598.1 - 4.9e-28 96.5 4.4 2.7e-12 46.4 0.2 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89598.1 - 3.1e-24 82.6 1.4 0.00011 22.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat SOCS_box PF07525.11 EMC89598.1 - 4.6e-07 29.5 0.0 7.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 SOCS box zf-H2C2_2 PF13465.1 EMC89599.1 - 5.2e-12 45.4 6.8 4.5e-07 29.8 0.4 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC89599.1 - 8.6e-08 32.0 0.6 8.6e-08 32.0 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC89599.1 - 9.9e-06 25.2 0.1 9.9e-06 25.2 0.1 1.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMC89599.1 - 0.0015 18.7 0.3 0.0015 18.7 0.2 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger DNA_RNApol_7kD PF03604.8 EMC89599.1 - 0.023 14.1 0.1 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz PF12171.3 EMC89599.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EMC89599.1 - 0.18 11.7 0.9 0.51 10.3 0.6 1.8 1 1 0 1 1 1 0 Zinc ribbon domain WD40 PF00400.27 EMC89603.1 - 6.5e-08 32.1 7.3 0.00049 19.8 0.1 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat SPATA6 PF14909.1 EMC89605.1 - 9e-23 80.8 0.9 1.6e-22 80.0 0.6 1.4 1 1 0 1 1 1 1 Spermatogenesis-assoc protein 6 CDC37_M PF08565.6 EMC89606.1 - 2.1e-41 141.2 1.8 3.8e-41 140.4 1.2 1.4 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain ADK PF00406.17 EMC89607.1 - 7.5e-31 107.0 0.0 8.9e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMC89607.1 - 3.4e-16 58.6 0.0 7.2e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EMC89607.1 - 0.047 14.5 0.1 0.088 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Matrilin_ccoil PF10393.4 EMC89607.1 - 0.06 12.7 0.2 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Myosin_tail_1 PF01576.14 EMC89608.1 - 1.9e-121 406.4 74.3 2.1e-121 406.2 51.5 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 EMC89608.1 - 1.2e-05 24.5 69.2 0.0024 16.9 21.1 4.1 1 1 4 5 5 5 4 Tropomyosin Reo_sigmaC PF04582.7 EMC89608.1 - 0.23 10.6 18.0 0.31 10.1 4.4 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein NikR_C PF08753.6 EMC89608.1 - 0.3 10.9 3.3 5.5 6.9 0.5 3.4 2 1 0 2 2 2 0 NikR C terminal nickel binding domain WEMBL PF05701.6 EMC89608.1 - 0.35 9.2 65.3 0.025 13.0 27.1 2.6 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 EMC89608.1 - 0.61 9.9 69.8 1.6 8.5 12.6 4.1 1 1 3 4 4 4 0 Tropomyosin like Laminin_I PF06008.9 EMC89608.1 - 0.61 9.3 56.3 0.82 8.9 12.7 3.2 1 1 2 3 3 3 0 Laminin Domain I DUF1664 PF07889.7 EMC89608.1 - 1.3 8.8 41.5 0.92 9.3 4.2 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 EMC89608.1 - 1.7 8.7 41.9 0.85 9.7 4.6 3.7 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 EMC89608.1 - 2 8.1 63.1 0.52 10.0 10.0 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 EMC89608.1 - 2.8 7.2 67.9 1.8 7.8 24.9 4.0 1 1 3 4 4 4 0 PspA/IM30 family HOOK PF05622.7 EMC89608.1 - 3.6 5.2 61.5 0.33 8.7 23.8 2.3 1 1 1 2 2 2 0 HOOK protein Filament PF00038.16 EMC89608.1 - 4.1 6.7 60.1 1 8.7 35.9 2.8 1 1 1 2 2 2 0 Intermediate filament protein IncA PF04156.9 EMC89608.1 - 8.9 5.8 62.8 0.91 9.0 14.4 4.0 1 1 3 4 4 4 0 IncA protein Auts2 PF15336.1 EMC89610.1 - 1e-107 359.0 17.6 1e-107 359.0 12.2 4.0 3 1 0 3 3 3 1 Autism susceptibility gene 2 protein BAF1_ABF1 PF04684.8 EMC89610.1 - 1.4 7.7 10.9 3.4 6.4 7.6 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Rep_fac_C PF08542.6 EMC89612.1 - 6e-23 80.6 0.3 2.8e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 EMC89612.1 - 2.5e-13 50.3 0.1 4.2e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMC89612.1 - 7.9e-12 45.1 0.0 1.7e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EMC89612.1 - 4.5e-07 29.8 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC89612.1 - 2.5e-06 27.5 0.0 0.00016 21.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMC89612.1 - 3.2e-06 27.3 0.3 0.00091 19.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMC89612.1 - 6.9e-06 25.7 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EMC89612.1 - 3.9e-05 23.2 0.0 7.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EMC89612.1 - 8.4e-05 21.8 0.0 0.0011 18.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EMC89612.1 - 0.00012 21.5 0.1 0.12 11.8 0.0 2.5 1 1 0 2 2 2 2 AAA-like domain Rad17 PF03215.10 EMC89612.1 - 0.00021 20.1 0.1 0.21 10.2 0.0 2.5 2 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 EMC89612.1 - 0.0004 20.0 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EMC89612.1 - 0.00049 19.6 1.0 0.08 12.4 0.0 2.9 1 1 2 3 3 3 1 DEAD/DEAH box helicase AAA_18 PF13238.1 EMC89612.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EMC89612.1 - 0.0013 17.8 0.1 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 ATPase MipZ RuvB_N PF05496.7 EMC89612.1 - 0.0014 17.7 0.0 0.0033 16.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EMC89612.1 - 0.0017 17.8 0.4 0.007 15.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMC89612.1 - 0.003 17.2 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EMC89612.1 - 0.0038 16.7 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 EMC89612.1 - 0.011 15.9 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EMC89612.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EMC89612.1 - 0.02 13.6 0.1 0.054 12.2 0.1 1.7 1 1 1 2 2 2 0 ArgK protein AAA_30 PF13604.1 EMC89612.1 - 0.022 14.3 0.4 0.2 11.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMC89612.1 - 0.023 14.4 0.2 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 NTPase SNF2_N PF00176.18 EMC89612.1 - 0.026 13.3 0.1 5.2 5.7 0.0 2.4 1 1 1 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.4 EMC89612.1 - 0.03 13.3 0.4 0.3 10.0 0.3 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EMC89612.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EMC89612.1 - 0.04 14.7 1.5 0.086 13.6 1.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC89612.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMC89612.1 - 0.064 13.4 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase T2SE PF00437.15 EMC89612.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EMC89612.1 - 0.099 12.9 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4597 PF15366.1 EMC89612.1 - 0.12 11.9 0.6 1.9 8.1 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4597) RRM_1 PF00076.17 EMC89614.1 - 2.1e-13 49.7 0.0 3.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89614.1 - 4.9e-10 39.2 0.0 7.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89614.1 - 4.7e-07 29.5 0.0 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 EMC89614.1 - 3.9 6.1 19.6 7.9 5.1 13.6 1.5 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DNA_pol_phi PF04931.8 EMC89615.1 - 9.2e-115 384.2 26.2 1.3e-114 383.7 18.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Mpp10 PF04006.7 EMC89615.1 - 0.022 13.1 20.1 0.035 12.5 13.9 1.3 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.5 EMC89615.1 - 1.7 7.6 21.4 4 6.3 14.8 1.6 1 1 0 1 1 1 0 BUD22 Daxx PF03344.10 EMC89615.1 - 3.4 6.0 21.8 5.4 5.3 15.1 1.2 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 EMC89617.1 - 1.2e-29 103.1 29.6 1.5e-29 102.8 20.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC89617.1 - 2.5e-12 46.1 9.2 2.5e-12 46.1 6.4 2.6 1 1 2 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 EMC89617.1 - 1e-06 27.1 1.3 1e-06 27.1 0.9 3.5 2 2 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 EMC89617.1 - 1.6e-05 23.4 20.1 0.0011 17.3 3.0 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1518 PF07469.7 EMC89618.1 - 2.4e-06 27.5 30.0 0.44 10.7 0.3 6.0 1 1 5 6 6 6 4 Domain of unknown function (DUF1518) Amelogenin PF02948.10 EMC89618.1 - 1.3 9.6 41.3 1.1 9.8 18.6 2.9 1 1 1 2 2 2 0 Amelogenin FlbT PF07378.6 EMC89618.1 - 4.2 7.2 12.8 1.2e+02 2.5 0.1 4.8 5 0 0 5 5 5 0 Flagellar protein FlbT DUF4573 PF15140.1 EMC89618.1 - 6.5 6.3 24.5 18 4.9 9.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4573) Collagen PF01391.13 EMC89619.1 - 1.8e-17 62.6 14.2 1e-05 24.9 3.0 3.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Tmemb_161AB PF10268.4 EMC89620.1 - 6.9e-237 786.6 14.3 7.8e-237 786.5 9.9 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB zf-C3HC4 PF00097.20 EMC89621.1 - 5.9e-11 41.8 9.1 1e-10 41.0 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC89621.1 - 2.4e-09 36.8 9.9 4e-09 36.1 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC89621.1 - 5.9e-09 35.4 6.2 9.1e-09 34.8 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC89621.1 - 1e-08 35.0 10.3 1.7e-08 34.3 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC89621.1 - 5.3e-07 29.2 6.4 8.3e-07 28.6 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMC89621.1 - 0.00013 21.9 7.4 0.0003 20.8 5.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMC89621.1 - 0.0081 15.8 2.4 0.0092 15.6 0.9 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMC89621.1 - 0.052 13.3 2.4 0.11 12.3 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 EMC89621.1 - 0.14 11.8 3.9 0.21 11.2 2.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EMC89621.1 - 0.62 9.9 11.0 1.1 9.1 7.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SRF-TF PF00319.13 EMC89622.1 - 1.6e-22 78.4 0.2 2.8e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 EMC89622.1 - 8.3e-14 50.9 0.0 1.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat EF-hand_1 PF00036.27 EMC89623.1 - 4.4e-22 75.6 13.7 2.9e-07 29.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC89623.1 - 4.2e-20 71.6 10.3 1e-09 38.3 1.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC89623.1 - 9.7e-19 65.5 11.4 2.6e-06 26.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EMC89623.1 - 3.6e-12 45.6 15.0 3.8e-07 29.6 0.4 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EMC89623.1 - 2.5e-11 42.3 15.3 9.1e-05 21.6 0.3 4.7 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMC89623.1 - 3.8e-06 26.7 0.2 0.064 13.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0231 PF06062.6 EMC89623.1 - 0.014 15.2 1.7 0.032 14.0 0.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) MgtE_N PF03448.12 EMC89623.1 - 0.048 13.9 0.7 0.048 13.9 0.5 2.5 1 1 2 3 3 3 0 MgtE intracellular N domain EF-hand_4 PF12763.2 EMC89623.1 - 0.048 13.3 3.7 0.05 13.3 0.2 2.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Cas_Csn2 PF09711.5 EMC89623.1 - 0.06 13.0 0.2 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) DUF4373 PF14297.1 EMC89623.1 - 0.27 11.5 2.6 29 5.0 0.0 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4373) RNA_pol_3_Rpc31 PF11705.3 EMC89624.1 - 2.4e-30 106.1 18.2 2.9e-30 105.9 12.6 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC27 PF09507.5 EMC89624.1 - 0.00059 19.1 14.2 0.00062 19.1 9.9 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PPP4R2 PF09184.6 EMC89624.1 - 0.32 10.5 16.8 0.39 10.2 11.6 1.1 1 0 0 1 1 1 0 PPP4R2 Daxx PF03344.10 EMC89624.1 - 0.47 8.8 25.8 0.57 8.6 17.9 1.0 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 EMC89624.1 - 1.2 7.9 14.2 1.6 7.5 9.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PA26 PF04636.8 EMC89624.1 - 2 7.0 6.1 2.4 6.7 4.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nop14 PF04147.7 EMC89624.1 - 2.7 5.7 21.5 3.2 5.5 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 EMC89624.1 - 2.9 7.2 16.8 4.3 6.7 11.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2413 PF10310.4 EMC89624.1 - 8.7 5.0 17.4 12 4.5 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 EMC89624.1 - 8.7 5.6 21.9 12 5.1 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LysM PF01476.15 EMC89625.1 - 6.8e-05 22.6 0.3 0.00016 21.4 0.0 1.8 2 0 0 2 2 2 1 LysM domain YqhR PF11085.3 EMC89625.1 - 0.032 13.7 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF4199 PF13858.1 EMC89625.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Calx-beta PF03160.9 EMC89626.1 - 1.5e-241 782.2 93.4 5.4e-16 58.3 0.0 37.7 38 0 0 38 38 38 32 Calx-beta domain Laminin_G_3 PF13385.1 EMC89626.1 - 3.3e-16 59.9 0.3 1.5e-15 57.7 0.1 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily 7tm_2 PF00002.19 EMC89626.1 - 2.7e-15 56.1 24.5 4.8e-15 55.3 17.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 EMC89626.1 - 1.6e-08 34.5 1.9 3.2e-08 33.5 1.3 1.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain EPTP PF03736.12 EMC89626.1 - 7.3e-07 28.8 6.1 0.0074 16.0 0.2 5.4 5 0 0 5 5 5 2 EPTP domain PAN_4 PF14295.1 EMC89626.1 - 0.22 11.2 0.5 0.48 10.1 0.3 1.5 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.6 EMC89626.1 - 1.1 9.1 0.1 3.8 7.4 0.1 1.9 1 0 0 1 1 1 0 PAN-like domain Arrestin_N PF00339.24 EMC89627.1 - 2e-35 121.8 0.1 1.5e-34 118.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMC89627.1 - 1.1e-23 83.8 0.0 2.2e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 EMC89627.1 - 0.0018 17.0 0.1 0.012 14.3 0.1 2.1 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Yae1_N PF09811.4 EMC89628.1 - 4.3e-15 54.9 55.7 1.3e+02 2.2 0.5 5.3 2 1 0 2 2 2 1 Essential protein Yae1, N terminal zf-C4 PF00105.13 EMC89629.1 - 1.1e-32 112.0 17.1 1.2e-32 111.8 11.8 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Peptidase_C98 PF15499.1 EMC89629.1 - 0.41 9.8 3.9 0.46 9.7 2.7 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Arb2 PF09757.4 EMC89631.1 - 4.5e-35 120.6 0.5 2.7e-34 118.1 0.0 2.2 2 0 0 2 2 2 1 Arb2 domain Abhydrolase_6 PF12697.2 EMC89631.1 - 0.00071 19.5 0.0 0.0017 18.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC89631.1 - 0.0034 17.1 0.0 0.0099 15.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC89631.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4495 PF14906.1 EMC89632.1 - 1.1e-127 425.4 12.1 1.1e-127 425.4 8.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4495) BRCT PF00533.21 EMC89633.1 - 0.00011 22.2 0.6 0.0018 18.3 0.2 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Ank PF00023.25 EMC89634.1 - 3.1e-20 70.8 0.4 8.5e-07 28.4 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EMC89634.1 - 7.6e-20 71.0 0.2 1.6e-10 41.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMC89634.1 - 5.3e-17 60.2 0.1 4.8e-05 23.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMC89634.1 - 1.1e-13 50.9 0.1 1.5e-05 25.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC89634.1 - 2.6e-13 50.0 0.0 1.4e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) C2 PF00168.25 EMC89635.1 - 8.1e-67 221.0 0.1 2.7e-23 81.6 0.0 3.4 3 0 0 3 3 3 3 C2 domain PRT_C PF08372.5 EMC89635.1 - 1.6e-07 30.9 2.7 2.8e-06 26.9 0.0 2.3 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.6 EMC89635.1 - 2.3e-05 23.3 2.1 4e-05 22.5 1.4 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CEP76-C2 PF15627.1 EMC89635.1 - 0.0027 17.2 0.0 0.45 10.0 0.0 2.7 2 0 0 2 2 2 2 CEP76 C2 domain COG5 PF10392.4 EMC89636.1 - 0.0016 18.4 18.3 0.018 14.9 0.1 3.4 1 1 2 3 3 3 2 Golgi transport complex subunit 5 RuvC PF02075.12 EMC89636.1 - 0.069 12.9 0.1 0.24 11.1 0.1 2.0 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC LPP PF04728.8 EMC89636.1 - 0.34 10.7 4.6 1.8 8.3 0.0 3.7 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.7 EMC89636.1 - 0.51 10.1 13.9 4 7.2 0.1 3.6 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_C_2 PF01322.15 EMC89636.1 - 1.7 9.2 7.3 13 6.3 2.8 3.1 3 1 0 3 3 3 0 Cytochrome C' TPR_11 PF13414.1 EMC89637.1 - 6.5e-62 205.1 76.7 3.5e-10 39.3 0.0 19.0 13 5 3 17 17 17 14 TPR repeat TPR_16 PF13432.1 EMC89637.1 - 7e-42 141.2 43.4 1.5e-07 31.8 0.6 16.4 15 3 5 20 20 18 10 Tetratricopeptide repeat TPR_1 PF00515.23 EMC89637.1 - 2e-37 125.2 84.4 4.6e-05 22.8 0.0 23.6 27 1 0 28 28 28 10 Tetratricopeptide repeat TPR_14 PF13428.1 EMC89637.1 - 5.4e-37 122.8 42.5 0.00091 19.6 0.8 22.4 15 6 9 24 24 22 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMC89637.1 - 1.1e-34 115.5 87.7 0.00047 19.8 0.3 25.4 26 1 0 27 27 25 10 Tetratricopeptide repeat TPR_19 PF14559.1 EMC89637.1 - 3.6e-34 116.9 59.3 0.00046 20.4 2.4 16.4 16 2 2 19 19 17 10 Tetratricopeptide repeat TPR_17 PF13431.1 EMC89637.1 - 2.6e-31 105.1 42.0 0.0067 16.5 0.0 20.4 19 1 1 20 20 20 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMC89637.1 - 6.8e-31 106.0 61.9 0.00025 20.8 0.3 15.8 9 3 8 18 18 18 12 Tetratricopeptide repeat TPR_8 PF13181.1 EMC89637.1 - 3.3e-20 70.2 71.9 0.01 15.5 0.0 20.5 21 2 2 23 23 21 7 Tetratricopeptide repeat TPR_7 PF13176.1 EMC89637.1 - 6.4e-10 38.0 42.2 0.49 10.3 0.0 17.2 20 1 0 20 20 19 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC89637.1 - 1.7e-07 30.9 18.0 0.13 12.1 0.0 8.6 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMC89637.1 - 5e-06 26.6 49.7 3.5 8.3 0.2 17.1 19 0 0 19 19 16 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMC89637.1 - 2e-05 23.8 52.7 0.0002 20.5 3.8 8.1 6 2 1 7 7 7 3 Tetratricopeptide repeat TolB_N PF04052.8 EMC89637.1 - 0.035 14.1 0.1 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 TolB amino-terminal domain TPR_20 PF14561.1 EMC89637.1 - 0.066 13.3 20.7 0.3 11.2 0.0 8.9 11 1 1 12 12 10 0 Tetratricopeptide repeat BTAD PF03704.12 EMC89637.1 - 0.49 10.6 0.0 0.49 10.6 0.0 5.1 5 0 0 5 5 4 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EMC89637.1 - 2.3 8.1 17.2 0.11 12.4 0.3 6.1 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Sulfatase PF00884.18 EMC89638.1 - 5.5e-43 147.3 0.1 1e-42 146.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EMC89638.1 - 2.6e-07 30.2 0.0 4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 EMC89638.1 - 9.4e-05 21.0 0.0 0.00018 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EMC89638.1 - 0.00014 21.3 0.1 0.00032 20.1 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 EMC89638.1 - 0.056 12.2 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4572 PF15139.1 EMC89638.1 - 0.1 12.4 1.6 0.88 9.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4572) Rieske_2 PF13806.1 EMC89639.1 - 1.2e-11 44.2 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 EMC89639.1 - 1.1e-09 37.7 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain BTB PF00651.26 EMC89640.1 - 4e-26 91.1 1.8 3.2e-18 65.7 0.3 3.5 3 0 0 3 3 3 2 BTB/POZ domain Ras PF00071.17 EMC89640.1 - 4e-06 26.3 0.0 8.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC89640.1 - 0.1 13.0 0.1 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ELL PF10390.4 EMC89641.1 - 1.6e-84 283.4 0.2 1.6e-84 283.4 0.1 2.6 1 1 1 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.8 EMC89641.1 - 2.6e-32 111.5 10.8 2.6e-32 111.5 7.5 2.6 2 0 0 2 2 2 1 Occludin homology domain DUF1925 PF09094.6 EMC89641.1 - 3.8 7.5 7.7 0.55 10.2 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1925) GnHR_trans PF12369.3 EMC89641.1 - 7.1 7.1 10.4 7.3 7.1 0.1 3.6 4 0 0 4 4 4 0 Gonadotropin hormone receptor transmembrane region Proho_convert PF12177.3 EMC89642.1 - 1.1e-25 88.8 2.0 1.1e-25 88.8 1.4 1.5 2 0 0 2 2 2 1 Prohormone convertase enzyme Peptidase_S8 PF00082.17 EMC89643.1 - 1.3e-59 201.6 3.6 1.7e-59 201.2 2.5 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EMC89643.1 - 7.2e-28 96.2 0.3 1.4e-27 95.3 0.2 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Calpain_inhib PF00748.14 EMC89644.1 - 1.6e-128 423.3 83.9 7.7e-39 133.0 11.8 6.1 5 1 1 6 6 6 5 Calpain inhibitor Peptidase_M1 PF01433.15 EMC89645.1 - 5.3e-114 381.3 0.3 7.5e-114 380.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMC89645.1 - 1e-50 172.8 0.8 1.2e-50 172.6 0.0 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMC89645.1 - 1.8e-18 66.8 0.1 3.3e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1077 PF06417.7 EMC89646.1 - 7e-12 44.7 0.0 8.3e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) tRNA_m1G_MT PF01746.16 EMC89647.1 - 1.9e-24 86.2 0.0 2.1e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF543 PF04418.7 EMC89647.1 - 0.0095 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF543) RNA_pol_I_A49 PF06870.7 EMC89648.1 - 3.3e-90 302.4 7.7 1.6e-76 257.3 3.3 2.0 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor Fib_alpha PF08702.5 EMC89648.1 - 0.61 10.2 3.6 0.19 11.8 0.3 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PT PF04886.7 EMC89649.1 - 3.2e-05 23.1 55.6 0.64 9.3 0.9 8.4 4 3 2 6 6 6 6 PT repeat zf-CCHC PF00098.18 EMC89650.1 - 3.1e-07 29.9 11.6 2.3e-05 24.0 1.4 5.1 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.1 EMC89650.1 - 0.0011 18.6 0.9 0.0011 18.6 0.6 4.1 3 1 1 4 4 4 2 Zinc knuckle zf-CCHC_2 PF13696.1 EMC89650.1 - 0.0073 15.7 2.5 0.0073 15.7 1.7 4.4 3 1 1 4 4 4 1 Zinc knuckle zf-CCHC_4 PF14392.1 EMC89650.1 - 0.031 13.9 0.3 0.031 13.9 0.2 3.4 4 0 0 4 4 4 0 Zinc knuckle RIG-I_C-RD PF11648.3 EMC89650.1 - 0.13 12.1 3.6 0.24 11.2 2.5 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I PAX PF00292.13 EMC89652.1 - 1.1e-73 244.8 0.7 1.7e-73 244.2 0.5 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_29 PF13551.1 EMC89652.1 - 2.9e-05 24.1 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EMC89652.1 - 4.9e-05 22.8 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 EMC89652.1 - 0.0018 19.0 0.1 0.067 13.9 0.0 2.5 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_IS1 PF12759.2 EMC89652.1 - 0.0082 15.5 0.3 0.048 13.0 0.0 2.1 2 0 0 2 2 2 1 InsA C-terminal domain Ribosomal_S13_N PF08069.7 EMC89652.1 - 0.022 14.6 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Homeobox PF00046.24 EMC89652.1 - 0.046 13.3 0.1 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox domain Lig_chan PF00060.21 EMC89653.1 - 4.5e-55 185.4 0.1 6.6e-55 184.8 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 EMC89653.1 - 7.9e-30 102.6 0.4 7.5e-29 99.5 0.1 2.6 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC89653.1 - 1.8e-20 73.1 0.0 2.8e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.23 EMC89653.1 - 1.1e-10 40.8 0.1 2.1e-10 39.9 0.0 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region DUF874 PF05917.6 EMC89654.1 - 0.076 11.8 1.1 0.09 11.6 0.7 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Pkinase PF00069.20 EMC89655.1 - 3.6e-68 229.5 0.0 4.6e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89655.1 - 7.7e-31 107.0 0.0 1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMC89655.1 - 0.0065 15.5 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Malic_M PF03949.10 EMC89656.1 - 3e-88 295.6 0.1 3.9e-88 295.3 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMC89656.1 - 1.1e-79 266.3 0.0 1.9e-79 265.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pol_alpha_B_N PF08418.5 EMC89656.1 - 0.13 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1992 PF09350.5 EMC89656.1 - 0.13 12.1 0.3 0.33 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) Lactamase_B PF00753.22 EMC89657.1 - 8.8e-14 51.5 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMC89657.1 - 5.3e-10 39.1 0.0 7.3e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EMC89657.1 - 1.4e-06 27.6 0.0 2.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 EMC89657.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II KH_1 PF00013.24 EMC89659.1 - 1.6e-19 69.3 1.7 1.2e-13 50.4 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EMC89659.1 - 4.3e-10 39.0 0.1 9e-07 28.4 0.0 2.8 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.1 EMC89659.1 - 2e-06 27.3 8.0 3e-06 26.8 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC89659.1 - 0.00023 21.1 8.1 0.00037 20.4 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_2 PF07650.12 EMC89659.1 - 0.039 13.5 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 KH domain zf-RING_2 PF13639.1 EMC89659.1 - 0.34 10.7 7.9 0.55 10.0 5.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EMC89659.1 - 0.61 9.8 6.6 1 9.1 4.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CAF-1_p150 PF11600.3 EMC89660.1 - 0.028 13.7 49.7 0.06 12.7 34.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDRGK PF09756.4 EMC89660.1 - 1.9 7.8 35.0 3.8 6.8 24.2 1.4 1 0 0 1 1 1 0 DDRGK domain MIP-T3 PF10243.4 EMC89660.1 - 2.7 6.3 40.4 4.2 5.7 28.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BMP2K_C PF15282.1 EMC89660.1 - 6.5 6.8 12.9 19 5.3 8.9 1.7 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus DUF1510 PF07423.6 EMC89660.1 - 7.5 5.8 25.2 12 5.2 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neogenin_C PF06583.7 EMC89661.1 - 4.4e-32 111.9 0.2 4.4e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 Neogenin C-terminus MBD_C PF14048.1 EMC89662.1 - 2.3e-37 127.4 0.1 3e-37 127.1 0.1 1.1 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 Pardaxin PF07425.6 EMC89662.1 - 0.048 13.0 0.9 0.12 11.7 0.6 1.7 1 0 0 1 1 1 0 Pardaxin IMS PF00817.15 EMC89663.1 - 6.6e-44 149.3 0.0 1.2e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMC89663.1 - 1.5e-10 41.1 0.1 2.7e-09 37.0 0.0 2.6 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMC89663.1 - 6.9e-06 25.8 0.0 2.8e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 IMS family HHH motif DUF4414 PF14377.1 EMC89663.1 - 9.6e-06 25.4 0.7 2.9e-05 23.9 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) HHH_5 PF14520.1 EMC89663.1 - 0.0012 18.9 0.3 0.0046 17.0 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EMC89663.1 - 0.0014 18.1 0.0 0.0046 16.4 0.0 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.3 EMC89663.1 - 0.0031 17.3 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus HHH PF00633.18 EMC89663.1 - 0.0089 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif START PF01852.14 EMC89664.1 - 4.4e-21 75.1 0.0 5e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 START domain SEO_C PF14577.1 EMC89664.1 - 0.093 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Ras PF00071.17 EMC89666.1 - 2.7e-54 182.9 0.0 3.3e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC89666.1 - 6.4e-16 58.9 0.0 9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC89666.1 - 8.6e-13 47.8 0.0 1.4e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC89666.1 - 0.00055 19.4 0.0 0.0015 17.9 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC89666.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMC89666.1 - 0.0048 16.0 0.1 0.016 14.3 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMC89666.1 - 0.0062 16.1 0.3 0.15 11.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMC89666.1 - 0.01 15.9 0.0 0.03 14.4 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EMC89666.1 - 0.11 12.0 0.1 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cep57_CLD_2 PF14197.1 EMC89667.1 - 0.0033 17.3 2.3 0.0033 17.3 1.6 3.9 2 1 1 3 3 3 1 Centrosome localisation domain of PPC89 Gp58 PF07902.6 EMC89667.1 - 0.0048 15.1 10.1 0.007 14.6 7.0 1.1 1 0 0 1 1 1 1 gp58-like protein DUF1359 PF07097.6 EMC89667.1 - 0.0057 16.6 2.2 0.01 15.8 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1359) SlyX PF04102.7 EMC89667.1 - 0.047 14.0 0.6 0.047 14.0 0.4 5.0 1 1 4 5 5 5 0 SlyX ATG16 PF08614.6 EMC89667.1 - 0.16 11.8 34.8 0.091 12.5 21.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GCOM2 PF15328.1 EMC89667.1 - 0.24 11.1 30.4 2.8 7.6 20.2 2.5 1 1 1 2 2 2 0 Putative GRINL1B complex locus protein 2 DUF3584 PF12128.3 EMC89667.1 - 0.29 8.4 34.7 0.09 10.1 20.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Laminin_I PF06008.9 EMC89667.1 - 0.81 8.9 30.8 0.9 8.8 3.1 2.4 1 1 1 2 2 2 0 Laminin Domain I Reo_sigmaC PF04582.7 EMC89667.1 - 0.82 8.7 4.2 0.7 9.0 1.6 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF724 PF05266.9 EMC89667.1 - 1 8.9 29.8 0.67 9.5 8.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) NPV_P10 PF05531.7 EMC89667.1 - 1.4 9.2 6.6 0.61 10.3 0.6 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Rootletin PF15035.1 EMC89667.1 - 3.1 7.7 36.8 0.46 10.4 15.5 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 EMC89667.1 - 9.1 3.9 22.8 0.2 9.4 2.0 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Collagen PF01391.13 EMC89669.1 - 1.6e-06 27.5 32.1 6.7e+02 -0.1 22.2 3.6 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) PITH PF06201.8 EMC89670.1 - 1.5e-45 154.7 0.0 2.2e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EMC89670.1 - 5.8e-15 54.8 0.0 1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Sad1_UNC PF07738.8 EMC89670.1 - 0.0064 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Glyco_transf_29 PF00777.13 EMC89671.1 - 3.5e-77 259.1 0.1 4.6e-77 258.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Homeobox PF00046.24 EMC89673.1 - 1.8e-11 43.4 1.2 2.8e-11 42.8 0.8 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC89673.1 - 4.5e-05 23.0 0.2 9.7e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Homeobox KN domain DUF2194 PF09960.4 EMC89673.1 - 0.054 11.5 0.2 0.052 11.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) PH_3 PF14593.1 EMC89673.1 - 0.071 13.0 0.6 0.087 12.7 0.4 1.1 1 0 0 1 1 1 0 PH domain LTXXQ PF07813.7 EMC89673.1 - 0.092 13.2 0.2 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein Ferrochelatase PF00762.14 EMC89674.1 - 1.1e-106 356.3 0.0 1.3e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase tRNA-synt_2 PF00152.15 EMC89675.1 - 2.1e-79 266.7 0.1 4.1e-79 265.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMC89675.1 - 1.4e-11 44.0 0.0 2.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.6 EMC89675.1 - 0.05 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) tRNA-synt_2d PF01409.15 EMC89675.1 - 0.12 11.4 0.1 4.2 6.5 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) WW PF00397.21 EMC89676.1 - 3.5e-48 161.0 27.7 3.2e-12 46.0 0.1 5.2 5 0 0 5 5 5 4 WW domain C2 PF00168.25 EMC89676.1 - 1.8e-23 82.1 0.1 4.7e-23 80.8 0.1 1.8 1 0 0 1 1 1 1 C2 domain HECT PF00632.20 EMC89676.1 - 1.7e-13 50.4 0.1 2.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Gag_p30 PF02093.11 EMC89677.1 - 1.3e-19 70.2 0.0 1.5e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein ANF_receptor PF01094.23 EMC89678.1 - 4.8e-17 61.7 0.0 5.7e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Cytochrom_B_N_2 PF13631.1 EMC89680.1 - 0.019 14.7 0.1 0.019 14.7 0.1 1.6 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Abhydro_lipase PF04083.11 EMC89681.1 - 5.8e-21 73.6 0.1 1.4e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMC89681.1 - 1.5e-17 63.9 0.0 3e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC89681.1 - 4.1e-09 36.6 0.0 5.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC89681.1 - 2.4e-07 30.6 0.0 6.1e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EMC89681.1 - 0.041 13.6 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase DLH PF01738.13 EMC89681.1 - 0.074 12.3 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.8 EMC89681.1 - 0.089 12.2 0.3 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EMC89682.1 - 5.8e-19 68.5 0.0 1.2e-18 67.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EMC89682.1 - 2.3e-16 58.9 0.1 9.2e-16 56.9 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EMC89682.1 - 1.9e-10 41.0 0.0 4.3e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC89682.1 - 7.4e-09 35.5 0.2 4e-07 29.8 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank PF00023.25 EMC89683.1 - 1.2e-31 106.9 1.0 7.8e-09 34.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EMC89683.1 - 1.5e-30 105.3 1.4 3.2e-15 56.2 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC89683.1 - 1.7e-27 94.8 2.2 3.1e-12 46.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC89683.1 - 2.4e-24 85.2 4.3 1.3e-07 31.9 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89683.1 - 6.1e-22 75.5 3.3 1.4e-05 24.8 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat DUF3098 PF11297.3 EMC89683.1 - 0.012 15.3 0.4 0.024 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Shigella_OspC PF06128.6 EMC89683.1 - 0.058 12.8 0.1 4.7 6.6 0.1 2.1 1 1 1 2 2 2 0 Shigella flexneri OspC protein DUF3447 PF11929.3 EMC89683.1 - 0.14 12.0 3.6 0.66 9.8 0.3 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF3447) RVT_1 PF00078.22 EMC89684.1 - 0.014 14.7 0.0 0.045 13.0 0.0 1.7 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_1 PF00561.15 EMC89685.1 - 7.2e-16 58.4 0.0 5.9e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC89685.1 - 9.6e-09 35.4 0.0 1.9e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC89685.1 - 2.9e-08 33.6 0.1 1.1e-07 31.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 EMC89685.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region BAAT_C PF08840.6 EMC89685.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydro_lipase PF04083.11 EMC89686.1 - 6.8e-21 73.3 0.0 1.6e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMC89686.1 - 3.1e-16 59.6 0.0 3.1e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMC89686.1 - 4.2e-08 33.3 0.0 8.7e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC89686.1 - 2.7e-07 30.4 0.0 1.1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family USP8_dimer PF08969.6 EMC89687.1 - 1.2e-18 67.1 0.1 1.2e-18 67.1 0.1 1.8 2 1 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.16 EMC89687.1 - 2.6e-16 59.3 0.0 7.2e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMC89687.1 - 8.9e-08 31.6 0.0 2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GxGYxYP PF14323.1 EMC89687.1 - 0.076 11.7 0.8 0.12 11.0 0.6 1.2 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Actin PF00022.14 EMC89688.1 - 4.1e-162 539.0 0.0 4.7e-162 538.8 0.0 1.0 1 0 0 1 1 1 1 Actin FA_hydroxylase PF04116.8 EMC89689.1 - 1.3e-14 54.5 18.6 1.3e-14 54.5 12.9 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_1 PF00561.15 EMC89690.1 - 4.7e-25 88.4 0.5 6.2e-25 88.1 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EMC89690.1 - 4.1e-23 80.5 0.0 9.2e-23 79.3 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EMC89690.1 - 3.7e-11 43.3 0.0 6.7e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC89690.1 - 7.7e-11 41.9 0.2 3.5e-10 39.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMC89690.1 - 0.0056 16.1 0.2 0.023 14.1 0.2 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EMC89690.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EMC89690.1 - 0.022 14.1 0.1 0.049 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EMC89691.1 - 2.3e-23 82.9 0.4 3.1e-23 82.5 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EMC89691.1 - 4.1e-23 80.5 0.0 9.2e-23 79.3 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EMC89691.1 - 7.9e-11 42.2 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC89691.1 - 1.5e-10 41.0 0.2 6.9e-10 38.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMC89691.1 - 0.0043 16.5 0.2 0.022 14.2 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EMC89691.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EMC89691.1 - 0.021 14.1 0.0 0.049 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) TPR_11 PF13414.1 EMC89692.1 - 3.1e-31 106.8 23.3 1.3e-05 24.6 0.1 7.1 6 1 1 7 7 7 7 TPR repeat TPR_12 PF13424.1 EMC89692.1 - 5e-27 93.6 16.4 1.5e-06 28.0 0.8 6.1 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMC89692.1 - 2.2e-26 89.5 23.0 0.00014 21.4 0.3 9.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 EMC89692.1 - 1.5e-24 84.5 17.2 2.7e-05 23.5 0.0 8.3 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 EMC89692.1 - 5.6e-24 82.4 0.6 0.0039 17.6 0.0 8.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMC89692.1 - 9e-22 75.1 18.6 0.00097 18.7 0.0 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMC89692.1 - 2e-21 76.0 9.1 1.5e-05 25.4 0.0 6.7 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMC89692.1 - 3.9e-20 71.9 6.0 0.00024 21.3 0.0 6.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMC89692.1 - 3.1e-17 61.2 14.6 0.067 13.4 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMC89692.1 - 1.7e-13 49.2 10.3 0.0086 15.8 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMC89692.1 - 3.9e-12 45.7 12.0 0.21 12.0 0.3 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMC89692.1 - 7.7e-08 32.0 8.5 0.41 10.6 0.1 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMC89692.1 - 1.4e-07 30.8 8.4 0.001 18.2 0.0 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC89692.1 - 1.8e-07 30.8 0.1 1.5 8.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 EMC89692.1 - 3.1e-07 29.5 11.3 1.4e-05 24.0 0.0 4.4 3 1 2 5 5 5 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 EMC89692.1 - 7.9e-06 25.9 23.3 0.56 10.3 0.5 5.7 3 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EMC89692.1 - 0.00025 20.8 7.0 3.1 7.7 0.0 6.1 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 EMC89692.1 - 0.00037 20.4 4.3 0.075 12.9 0.2 4.1 4 2 0 4 4 4 1 Tetratricopeptide repeat Orthopox_B11R PF07033.6 EMC89692.1 - 0.0021 17.4 1.9 0.0043 16.4 0.7 2.1 2 0 0 2 2 1 1 Orthopoxvirus B11R protein RPN7 PF10602.4 EMC89692.1 - 0.0033 16.8 14.6 0.11 11.8 0.7 5.4 5 2 1 6 6 6 1 26S proteasome subunit RPN7 TPR_20 PF14561.1 EMC89692.1 - 0.022 14.8 4.7 5.2 7.2 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TOM20_plant PF06552.7 EMC89692.1 - 0.064 12.8 5.7 13 5.3 0.1 4.6 3 2 3 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 SPOB_a PF14689.1 EMC89692.1 - 0.065 12.8 6.0 2 8.0 0.1 4.1 5 0 0 5 5 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain PPR PF01535.15 EMC89692.1 - 0.12 12.4 3.9 4 7.6 0.0 3.8 4 0 0 4 4 3 0 PPR repeat Apc5 PF12862.2 EMC89692.1 - 0.19 11.5 6.0 0.12 12.2 1.0 3.3 3 1 1 4 4 3 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.7 EMC89692.1 - 0.31 10.9 11.1 2.4 8.0 0.8 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat NSF PF02071.15 EMC89692.1 - 0.56 10.9 6.5 21 6.3 0.3 4.1 4 0 0 4 4 2 0 Aromatic-di-Alanine (AdAR) repeat Fis1_TPR_C PF14853.1 EMC89692.1 - 7.3 6.5 21.3 0.52 10.2 0.1 7.1 9 0 0 9 9 9 0 Fis1 C-terminal tetratricopeptide repeat MFS_1 PF07690.11 EMC89693.1 - 2.7e-37 128.3 33.4 1.6e-20 73.1 9.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC89693.1 - 6.4e-05 22.6 6.7 0.12 12.1 0.2 4.4 4 1 1 5 5 5 2 MFS_1 like family Fumble PF03630.9 EMC89694.1 - 9e-148 491.6 0.1 1e-147 491.4 0.1 1.0 1 0 0 1 1 1 1 Fumble Kinesin PF00225.18 EMC89695.1 - 3e-92 308.8 4.2 3e-92 308.8 2.9 4.1 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EMC89695.1 - 0.006 15.8 42.8 0.0065 15.6 2.8 5.6 4 1 1 5 5 5 4 Reovirus sigma C capsid protein 7tm_1 PF00001.16 EMC89696.1 - 4.9e-78 261.8 12.0 5.9e-78 261.5 8.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC89696.1 - 1.6e-05 24.1 12.5 3e-05 23.3 8.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4491 PF14898.1 EMC89696.1 - 4.3 7.5 7.9 1.3 9.2 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) RNase_P_p30 PF01876.11 EMC89697.1 - 8.6e-53 177.5 0.0 1.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 PTS_EIIA_2 PF00359.17 EMC89697.1 - 0.038 13.7 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Ank PF00023.25 EMC89698.1 - 3.2e-29 99.2 0.0 5.9e-10 38.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EMC89698.1 - 9e-29 99.6 0.6 2.1e-21 76.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC89698.1 - 8.3e-23 79.9 0.5 1.5e-07 31.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89698.1 - 5.6e-22 75.6 0.0 3.1e-06 26.9 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EMC89698.1 - 2.2e-20 72.6 0.0 8.7e-11 42.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) CLU_N PF15044.1 EMC89698.1 - 0.032 14.3 0.3 0.77 9.9 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial function, CLU-N-term DUF1843 PF08898.5 EMC89698.1 - 0.064 13.2 1.4 0.75 9.8 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Phage_Nu1 PF07471.7 EMC89698.1 - 0.12 11.8 1.9 0.2 11.0 1.3 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 zf-C3HC4 PF00097.20 EMC89699.1 - 5e-08 32.4 11.5 5e-08 32.4 8.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC89699.1 - 4.4e-07 29.8 11.1 4.4e-07 29.8 7.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC89699.1 - 2.7e-05 23.8 9.5 2.7e-05 23.8 6.6 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EMC89699.1 - 0.00012 21.7 10.5 0.00012 21.7 7.3 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC89699.1 - 0.00015 21.5 10.5 0.00015 21.5 7.3 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EMC89699.1 - 0.0021 17.6 8.4 0.0021 17.6 5.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EMC89699.1 - 0.0053 16.2 7.5 0.01 15.3 5.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EMC89699.1 - 0.031 14.0 3.0 0.031 14.0 2.1 2.6 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMC89699.1 - 0.13 11.9 10.0 0.056 13.1 4.4 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 EMC89699.1 - 1.5 8.9 11.7 1.5 8.9 5.8 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger Zn_Tnp_IS1595 PF12760.2 EMC89699.1 - 8.2 6.3 13.1 1.4 8.8 0.1 3.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain CBM_21 PF03370.8 EMC89700.1 - 2.8e-36 123.9 2.8 4e-36 123.4 1.9 1.2 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EMC89700.1 - 0.0042 17.1 0.5 0.0097 15.9 0.4 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Ank_2 PF12796.2 EMC89701.1 - 6.7e-163 529.5 64.5 4.6e-24 84.5 0.6 9.6 3 3 9 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EMC89701.1 - 3.7e-135 433.5 48.5 6.7e-12 44.5 0.2 18.5 21 0 0 21 21 21 15 Ankyrin repeat Ank_5 PF13857.1 EMC89701.1 - 1.5e-108 352.3 49.7 3.6e-14 52.4 0.2 15.8 5 5 13 18 18 18 15 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC89701.1 - 1.7e-107 350.1 23.7 4.1e-14 52.6 0.2 14.4 7 5 6 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89701.1 - 5.1e-95 301.7 31.7 2.1e-07 30.5 0.1 18.1 20 0 0 20 20 20 15 Ankyrin repeat PARP PF00644.15 EMC89701.1 - 9.2e-27 93.8 3.8 2.6e-24 85.7 2.6 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.12 EMC89701.1 - 1.4e-13 50.4 0.1 3.6e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC89701.1 - 4e-11 42.9 0.2 9.5e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Shigella_OspC PF06128.6 EMC89701.1 - 5e-06 26.2 0.0 1.5 8.2 0.0 4.8 4 0 0 4 4 4 1 Shigella flexneri OspC protein Vps39_1 PF10366.4 EMC89701.1 - 0.00019 21.4 1.0 1 9.4 0.0 3.5 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 7tm_1 PF00001.16 EMC89702.1 - 4.7e-81 271.7 13.9 5.7e-81 271.4 9.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC89702.1 - 1.2e-09 37.6 10.8 4.8e-09 35.7 7.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC89702.1 - 3.5e-06 26.3 16.5 5.6e-06 25.6 5.7 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx SARS_3b PF12383.3 EMC89702.1 - 0.041 13.8 0.4 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein DUF621 PF04789.10 EMC89702.1 - 2.2 7.1 13.0 6.7 5.6 9.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF621) 7TM_GPCR_Srw PF10324.4 EMC89702.1 - 9.6 5.2 16.0 22 4.0 8.9 2.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw RabGAP-TBC PF00566.13 EMC89703.1 - 3.8e-47 160.5 0.0 6.8e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CBF PF03914.12 EMC89704.1 - 8.3e-37 126.1 0.3 8.3e-37 126.1 0.2 2.2 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 EMC89704.1 - 2.9e-33 113.9 3.2 2.9e-33 113.9 2.2 3.4 4 0 0 4 4 4 1 Nucleolar complex-associated protein PI-PLC-X PF00388.14 EMC89705.1 - 4e-60 201.4 0.0 9.9e-60 200.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMC89705.1 - 3.9e-35 120.3 0.0 8.7e-33 112.8 0.0 3.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain RasGEF PF00617.14 EMC89705.1 - 1.3e-24 86.9 0.0 3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RA PF00788.18 EMC89705.1 - 1e-20 74.0 0.1 2.2e-17 63.3 0.1 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C2 PF00168.25 EMC89705.1 - 4.6e-09 36.0 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain GDPD PF03009.12 EMC89705.1 - 0.053 13.0 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family ADK PF00406.17 EMC89706.1 - 9.8e-22 77.4 0.4 3.1e-18 66.1 0.2 2.6 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 EMC89706.1 - 4.7e-15 56.4 1.3 4e-07 30.8 0.0 3.7 2 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EMC89706.1 - 8.2e-10 39.0 2.7 1.9e-05 24.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA PF00004.24 EMC89706.1 - 2.4e-06 27.8 0.0 0.056 13.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMC89706.1 - 9e-06 25.6 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain SKI PF01202.17 EMC89706.1 - 1.2e-05 25.2 0.7 0.05 13.4 0.0 3.2 2 1 0 2 2 2 2 Shikimate kinase AAA_19 PF13245.1 EMC89706.1 - 4.4e-05 23.1 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EMC89706.1 - 5.2e-05 23.4 0.3 0.014 15.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMC89706.1 - 9.3e-05 22.4 0.3 0.18 11.7 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 EMC89706.1 - 9.8e-05 22.6 1.2 0.5 10.6 0.0 3.2 3 0 0 3 3 3 2 ABC transporter KTI12 PF08433.5 EMC89706.1 - 0.00056 19.2 0.9 0.48 9.5 0.0 2.8 3 0 0 3 3 3 2 Chromatin associated protein KTI12 NACHT PF05729.7 EMC89706.1 - 0.001 18.7 0.0 0.0027 17.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 EMC89706.1 - 0.0012 18.5 0.0 0.041 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EMC89706.1 - 0.004 17.1 2.3 3 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EMC89706.1 - 0.0072 15.9 0.0 0.25 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMC89706.1 - 0.0087 15.5 0.2 0.4 10.0 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain RuvB_N PF05496.7 EMC89706.1 - 0.0095 15.0 0.2 1.1 8.2 0.0 2.9 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 EMC89706.1 - 0.023 14.6 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EMC89706.1 - 0.026 14.7 0.2 9.1 6.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase ZZ PF00569.12 EMC89706.1 - 0.032 13.7 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Zeta_toxin PF06414.7 EMC89706.1 - 0.034 13.2 0.0 0.58 9.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 EMC89706.1 - 0.036 13.2 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EMC89706.1 - 0.06 13.0 0.1 14 5.3 0.0 2.8 2 1 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 EMC89706.1 - 0.16 11.4 0.7 6.2 6.2 0.0 3.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family PPV_E1_C PF00519.12 EMC89706.1 - 0.19 10.2 0.2 9.7 4.6 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase G-alpha PF00503.15 EMC89706.1 - 0.27 9.8 6.2 2.6 6.6 0.0 2.9 2 1 0 3 3 3 0 G-protein alpha subunit DUF1268 PF06896.6 EMC89706.1 - 0.51 10.6 7.5 2.1 8.6 0.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF1268) TPX2 PF06886.6 EMC89706.1 - 3.3 7.8 9.6 23 5.1 0.2 2.9 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Tbf5 PF06331.7 EMC89707.1 - 0.027 14.2 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 zf-FCS PF06467.9 EMC89708.1 - 0.017 14.7 6.1 0.31 10.7 1.2 2.7 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 EMC89708.1 - 0.13 12.4 5.7 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3449 PF11931.3 EMC89708.1 - 0.24 10.9 3.0 3 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-C2H2 PF00096.21 EMC89708.1 - 3.8 8.0 8.4 22 5.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Njmu-R1 PF15053.1 EMC89709.1 - 3.5e-195 647.6 1.2 3.9e-195 647.4 0.9 1.0 1 0 0 1 1 1 1 Mjmu-R1-like protein family Rhomboid PF01694.17 EMC89710.1 - 2.2e-33 115.3 10.9 2.2e-33 115.3 7.6 2.0 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.1 EMC89710.1 - 8.6e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMC89710.1 - 7.6e-07 28.6 0.0 8.6e-05 22.0 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC89710.1 - 9.9e-07 27.6 0.0 0.016 14.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC89710.1 - 0.0032 17.2 0.0 0.047 13.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.1 EMC89710.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF_assoc_2 PF08356.7 EMC89711.1 - 6.5e-35 118.7 0.0 2.1e-34 117.1 0.0 1.9 2 0 0 2 2 2 1 EF hand associated Miro PF08477.8 EMC89711.1 - 1.7e-32 112.4 0.0 3.8e-15 56.4 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EMC89711.1 - 6.5e-31 105.4 2.2 8.5e-31 105.0 0.3 2.0 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 EMC89711.1 - 2.7e-23 82.1 0.2 4.1e-16 58.7 0.0 2.7 2 1 0 2 2 2 2 Ras family EF-hand_1 PF00036.27 EMC89711.1 - 2.6e-06 26.3 2.2 0.048 12.9 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC89711.1 - 9.8e-06 25.6 0.2 0.21 11.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC89711.1 - 1.4e-05 24.5 4.6 0.0081 15.9 0.0 3.3 3 0 0 3 3 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC89711.1 - 0.0012 18.4 1.2 0.22 11.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair MMR_HSR1 PF01926.18 EMC89711.1 - 0.0017 18.2 0.0 0.79 9.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC89711.1 - 0.008 16.0 0.0 0.59 9.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Rad4 PF03835.10 EMC89711.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain AAA_14 PF13173.1 EMC89711.1 - 0.055 13.3 0.0 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMC89711.1 - 0.085 13.1 0.0 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter EF-hand_5 PF13202.1 EMC89711.1 - 0.14 11.5 2.7 3.1 7.2 0.3 2.5 2 0 0 2 2 2 0 EF hand SPRY PF00622.23 EMC89712.1 - 4.9e-17 62.1 0.1 5.8e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 SPRY domain ArfGap PF01412.13 EMC89713.1 - 2.4e-26 91.7 0.1 5e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EMC89713.1 - 9.4e-16 57.9 0.4 5.4e-07 29.7 0.1 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EMC89713.1 - 4.7e-13 49.3 1.5 2.2e-05 24.6 0.1 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EMC89713.1 - 8.6e-09 35.3 1.4 0.0013 18.7 0.0 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EMC89713.1 - 7.4e-05 22.6 0.3 0.00048 20.0 0.0 2.3 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology VEFS-Box PF09733.4 EMC89715.1 - 4.3e-56 188.4 3.1 8.6e-56 187.5 2.1 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-H2C2_5 PF13909.1 EMC89715.1 - 1.4 9.2 5.1 5.6 7.3 3.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc-finger domain RBD-FIP PF09457.5 EMC89716.1 - 5e-13 48.6 2.9 5e-13 48.6 2.0 4.9 5 1 1 6 6 6 1 FIP domain bZIP_1 PF00170.16 EMC89716.1 - 0.00098 19.0 7.9 0.00098 19.0 5.5 6.1 4 1 2 7 7 7 2 bZIP transcription factor bZIP_2 PF07716.10 EMC89716.1 - 0.0033 17.2 4.4 0.0033 17.2 3.1 6.6 6 1 0 6 6 6 2 Basic region leucine zipper DUF904 PF06005.7 EMC89716.1 - 0.014 15.6 8.9 0.014 15.6 6.2 5.8 2 2 2 4 4 4 0 Protein of unknown function (DUF904) Shugoshin_N PF07558.6 EMC89716.1 - 0.14 11.8 17.3 1.9 8.2 0.7 4.6 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EMC89716.1 - 0.92 9.0 39.3 0.025 14.0 1.8 5.4 4 2 2 6 6 6 0 Septum formation initiator TMF_DNA_bd PF12329.3 EMC89716.1 - 1.6 8.6 55.4 0.92 9.3 7.3 5.1 3 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Leu_zip PF15294.1 EMC89716.1 - 6.3 5.8 46.7 7.9 5.4 4.1 3.6 1 1 1 3 3 3 0 Leucine zipper FlxA PF14282.1 EMC89716.1 - 9.2 6.2 37.5 1.8 8.5 4.2 4.9 2 1 2 4 4 4 0 FlxA-like protein Ax_dynein_light PF10211.4 EMC89716.1 - 9.9 5.9 45.5 5.2 6.8 7.1 4.0 1 1 3 4 4 4 0 Axonemal dynein light chain EF-hand_1 PF00036.27 EMC89717.1 - 0.0027 16.8 0.2 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EMC89717.1 - 0.0069 16.4 0.0 0.0095 16.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC89717.1 - 0.018 14.9 0.2 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain Peptidase_S10 PF00450.17 EMC89718.1 - 4.7e-87 292.8 0.2 5.2e-87 292.6 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ACP_syn_III_C PF08541.5 EMC89718.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal zf-C3HC4_4 PF15227.1 EMC89720.1 - 1.1e-08 34.7 8.9 1.2e-08 34.6 6.2 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMC89720.1 - 9.3e-08 31.9 8.3 9.9e-08 31.8 5.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC89720.1 - 1.6e-07 30.8 7.0 1.7e-07 30.7 4.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC89720.1 - 4.6e-07 29.5 6.9 4.8e-07 29.4 4.8 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC89720.1 - 7e-06 25.6 5.7 7.9e-06 25.4 3.9 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMC89720.1 - 1.4e-05 24.6 6.7 1.5e-05 24.5 4.6 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC89720.1 - 8.1e-05 22.2 8.1 9.7e-05 22.0 5.6 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EMC89720.1 - 0.0093 15.7 4.2 0.0096 15.6 2.9 1.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EMC89720.1 - 0.091 12.3 1.8 0.11 12.0 1.2 1.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 EMC89720.1 - 0.1 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 U-box domain IBR PF01485.16 EMC89720.1 - 1.9 8.4 7.7 19 5.2 5.3 2.0 1 1 0 1 1 1 0 IBR domain zf-rbx1 PF12678.2 EMC89720.1 - 2.8 8.1 6.2 15 5.8 4.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Tfb4 PF03850.9 EMC89720.1 - 3.7 6.7 7.6 3.8 6.6 5.3 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4543 PF15076.1 EMC89721.1 - 4.1e-47 158.0 2.7 4.9e-47 157.8 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) Noggin PF05806.7 EMC89722.1 - 1.9e-103 344.4 0.4 2.1e-103 344.3 0.2 1.0 1 0 0 1 1 1 1 Noggin SulA PF03846.9 EMC89723.1 - 0.0045 16.6 0.7 0.094 12.4 0.1 2.8 3 0 0 3 3 3 1 Cell division inhibitor SulA SPRY PF00622.23 EMC89724.1 - 4.3e-06 26.8 2.0 6.1e-06 26.3 0.4 2.0 2 0 0 2 2 2 1 SPRY domain PRY PF13765.1 EMC89724.1 - 0.00056 19.3 0.0 0.0019 17.6 0.0 1.9 1 0 0 1 1 1 1 SPRY-associated domain zf-B_box PF00643.19 EMC89724.1 - 0.0012 18.6 11.6 0.0034 17.2 8.0 1.8 1 0 0 1 1 1 1 B-box zinc finger DUF1875 PF08961.5 EMC89724.1 - 0.14 11.4 6.4 0.32 10.2 4.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DUF848 PF05852.6 EMC89724.1 - 0.22 11.3 9.8 0.33 10.7 5.8 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) WWbp PF10349.4 EMC89726.1 - 3e-20 73.2 17.1 3e-20 73.2 11.8 2.3 1 1 1 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 EMC89726.1 - 2e-14 52.8 0.0 2.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 EMC89726.1 - 0.009 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 EMC89726.1 - 0.026 14.7 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain C2 PF00168.25 EMC89727.1 - 2.8e-39 132.8 0.0 3.8e-20 71.5 0.0 2.7 2 1 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.4 EMC89727.1 - 1.7e-21 76.4 4.2 5.9e-19 68.2 2.9 3.2 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain zf-CCCH PF00642.19 EMC89728.1 - 2.4e-05 23.9 6.0 7.1e-05 22.3 0.7 7.0 8 0 0 8 8 8 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EMC89728.1 - 0.00018 21.1 10.5 0.00018 21.1 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.3 EMC89728.1 - 0.0016 17.7 3.3 0.0024 17.1 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Fez1 PF06818.10 EMC89728.1 - 0.0075 16.3 11.1 0.015 15.3 7.7 1.4 1 0 0 1 1 1 1 Fez1 Laminin_II PF06009.7 EMC89728.1 - 0.011 15.4 1.4 0.022 14.5 1.0 1.4 1 0 0 1 1 1 0 Laminin Domain II WEMBL PF05701.6 EMC89728.1 - 0.065 11.6 11.8 0.096 11.1 8.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF874 PF05917.6 EMC89728.1 - 0.086 11.6 4.8 0.14 11.0 3.3 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Mnd1 PF03962.10 EMC89728.1 - 0.098 12.3 13.1 1.2 8.7 8.3 2.5 2 1 0 2 2 2 0 Mnd1 family DUF2205 PF10224.4 EMC89728.1 - 0.74 9.4 4.3 0.26 10.8 0.7 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) APG6 PF04111.7 EMC89728.1 - 0.99 8.3 12.4 1.6 7.6 8.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 EMC89728.1 - 1.6 5.9 13.2 2.2 5.5 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PID PF00640.18 EMC89729.1 - 0.00016 21.6 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HCNGP PF07818.8 EMC89731.1 - 1.7e-37 127.3 1.1 3e-37 126.5 0.8 1.4 1 0 0 1 1 1 1 HCNGP-like protein DUF2051 PF09738.4 EMC89731.1 - 0.011 15.0 0.3 0.011 15.0 0.2 1.6 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) NOA36 PF06524.7 EMC89731.1 - 2.9 7.0 11.4 4.8 6.3 7.4 1.7 2 0 0 2 2 2 0 NOA36 protein DEAD PF00270.24 EMC89732.1 - 3.9e-21 75.2 0.1 9.4e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ5 PF06959.6 EMC89732.1 - 1.2e-19 70.8 11.9 2.9e-19 69.5 8.2 1.6 1 0 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) Helicase_C PF00271.26 EMC89732.1 - 1.7e-17 63.0 0.0 2.9e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMC89732.1 - 0.00044 20.1 0.0 0.0016 18.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3593 PF12159.3 EMC89733.1 - 0.0012 18.5 0.1 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Shisa PF13908.1 EMC89733.1 - 0.004 17.3 1.9 0.0042 17.2 1.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 EMC89733.1 - 0.039 13.5 0.3 0.054 13.1 0.2 1.1 1 0 0 1 1 1 0 IncA protein Corona_S2 PF01601.11 EMC89733.1 - 0.094 10.8 7.8 0.11 10.6 5.4 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.6 EMC89733.1 - 0.43 8.0 8.4 0.4 8.1 5.8 1.0 1 0 0 1 1 1 0 Prominin MyTH4 PF00784.12 EMC89734.1 - 4.9e-30 103.8 0.1 1.2e-28 99.3 0.0 2.5 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.13 EMC89734.1 - 1.5e-09 38.0 1.6 2.2e-09 37.5 0.3 1.9 2 0 0 2 2 2 1 FERM central domain SH3_2 PF07653.12 EMC89735.1 - 1.7e-11 43.3 0.0 2.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC89735.1 - 6.7e-08 31.9 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC89735.1 - 0.0036 16.6 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Myosin_head PF00063.16 EMC89736.1 - 2.2e-187 624.2 0.1 2.6e-187 624.0 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.12 EMC89736.1 - 1.4e-17 63.7 0.1 7.7e-17 61.2 0.0 2.3 2 0 0 2 2 2 1 MyTH4 domain IQ PF00612.22 EMC89736.1 - 4.8e-07 28.8 12.2 1e-05 24.7 1.4 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_17 PF13207.1 EMC89736.1 - 0.00078 20.2 0.0 0.0028 18.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMC89736.1 - 0.0016 18.5 0.1 0.015 15.4 0.0 2.7 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EMC89736.1 - 0.0046 16.9 0.3 0.018 15.0 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain T2SE PF00437.15 EMC89736.1 - 0.0087 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EMC89736.1 - 0.0087 15.1 0.0 0.024 13.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EMC89736.1 - 0.013 15.2 0.0 0.047 13.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EMC89736.1 - 0.033 14.0 1.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EMC89736.1 - 0.035 14.1 0.5 0.16 12.0 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain UPF0079 PF02367.12 EMC89736.1 - 0.038 13.6 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EMC89736.1 - 0.044 12.6 0.0 0.12 11.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EMC89736.1 - 0.075 13.3 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMC89736.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EMC89736.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter tRNA_int_end_N2 PF12928.2 EMC89737.1 - 9.6e-16 57.0 0.1 2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term 7tm_1 PF00001.16 EMC89738.1 - 2.3e-54 184.2 22.6 2.7e-54 184.0 15.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC89738.1 - 2e-10 40.2 21.1 2.3e-10 40.0 14.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC89738.1 - 0.0009 18.4 10.9 0.0009 18.4 7.5 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HemY_N PF07219.8 EMC89738.1 - 7.5 6.1 8.6 0.69 9.4 0.7 2.5 2 0 0 2 2 2 0 HemY protein N-terminus SH3_1 PF00018.23 EMC89740.1 - 3.4e-34 115.9 0.9 1.2e-16 59.7 0.0 2.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EMC89740.1 - 2e-30 104.1 0.4 9.2e-16 57.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMC89740.1 - 3e-26 90.6 0.0 6.4e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.19 EMC89740.1 - 1e-24 86.1 0.0 1.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 EMC89740.1 - 0.0043 17.2 0.2 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.8 EMC89740.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain MIF4G PF02854.14 EMC89741.1 - 1.3e-07 31.2 1.8 1.8e-07 30.8 1.2 1.2 1 0 0 1 1 1 1 MIF4G domain Ribosomal_S7 PF00177.16 EMC89742.1 - 1e-41 141.9 1.5 1.2e-41 141.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pox_D5 PF03288.11 EMC89742.1 - 0.044 14.0 1.6 3.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus D5 protein-like VHS PF00790.14 EMC89743.1 - 9.3e-46 154.9 1.6 3.7e-45 153.0 0.0 2.3 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 EMC89743.1 - 1.7e-29 101.7 3.0 1.7e-29 101.7 2.1 2.1 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EMC89743.1 - 9.4e-29 100.0 0.0 1.7e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain KAT11 PF08214.6 EMC89743.1 - 0.0047 16.0 0.5 0.0071 15.4 0.3 1.2 1 0 0 1 1 1 1 Histone acetylation protein UCH PF00443.24 EMC89743.1 - 0.035 13.2 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Usg PF06233.7 EMC89743.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Usg-like family RTTN_N PF14726.1 EMC89743.1 - 0.29 11.7 1.9 6.1 7.4 0.1 2.7 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Rad60-SLD PF11976.3 EMC89744.1 - 1e-26 92.3 0.1 1.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMC89744.1 - 1.2e-12 47.0 0.1 1.5e-12 46.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin family NT5C PF06941.7 EMC89746.1 - 8.5e-55 185.2 0.0 9.5e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Arm PF00514.18 EMC89747.1 - 6.4e-11 41.6 0.0 5.4e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMC89747.1 - 0.00056 20.1 0.0 0.0071 16.6 0.0 2.1 1 1 0 1 1 1 1 HEAT repeats RICTOR_N PF14664.1 EMC89747.1 - 0.005 15.4 0.9 0.0078 14.8 0.5 1.6 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Arm_2 PF04826.8 EMC89747.1 - 0.021 13.9 0.1 0.99 8.4 0.0 2.0 1 1 1 2 2 2 0 Armadillo-like GRIP PF01465.15 EMC89747.1 - 0.027 13.9 0.5 0.32 10.5 0.0 2.6 2 0 0 2 2 2 0 GRIP domain WAPL PF07814.8 EMC89747.1 - 0.03 13.0 0.3 0.061 12.0 0.1 1.7 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin Adaptin_N PF01602.15 EMC89747.1 - 0.052 11.8 0.7 0.09 11.0 0.5 1.5 1 1 0 1 1 1 0 Adaptin N terminal region HEAT PF02985.17 EMC89747.1 - 0.086 12.9 0.0 7.2 6.9 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat MFS_1 PF07690.11 EMC89748.1 - 7.2e-39 133.4 46.1 8.1e-33 113.5 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB_2 PF02214.17 EMC89749.1 - 2e-11 43.9 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EMC89749.1 - 0.0054 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PadR PF03551.9 EMC89749.1 - 0.11 12.2 0.2 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Neur_chan_LBD PF02931.18 EMC89751.1 - 2.5e-23 82.3 2.1 3e-23 82.1 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 EMC89751.1 - 0.012 15.4 2.6 0.02 14.7 1.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4369 PF14289.1 EMC89751.1 - 0.037 14.0 0.0 0.067 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4369) RF-1 PF00472.15 EMC89752.1 - 8.6e-18 64.2 2.8 1.2e-17 63.7 1.9 1.3 1 0 0 1 1 1 1 RF-1 domain DUF3540 PF12059.3 EMC89753.1 - 1.6 8.2 11.1 6.7 6.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) DUF1664 PF07889.7 EMC89753.1 - 2.2 8.0 26.1 8.8 6.1 0.5 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF2573 PF10835.3 EMC89753.1 - 4.2 7.4 10.6 5.6 7.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2573) FliD_C PF07195.7 EMC89753.1 - 4.5 6.4 18.3 0.39 9.9 2.7 3.7 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus BLOC1_2 PF10046.4 EMC89753.1 - 6.2 7.0 35.4 0.031 14.3 8.5 4.9 4 2 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EMC89753.1 - 6.5 5.8 8.7 3 6.9 2.0 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Hid1 PF12722.2 EMC89754.1 - 7.4e-246 818.1 0.0 1.2e-244 814.1 0.0 2.0 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EMC89754.1 - 8.7e-230 764.3 0.0 1.1e-229 764.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Otopetrin PF03189.8 EMC89755.1 - 8.9e-21 74.3 24.3 9.7e-13 47.9 9.8 3.0 1 1 1 2 2 2 2 Otopetrin Ank_2 PF12796.2 EMC89756.1 - 1.2e-23 83.2 0.1 8.7e-19 67.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC89756.1 - 2.8e-23 81.8 2.0 1.6e-12 47.6 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMC89756.1 - 5.9e-22 76.3 2.8 8.4e-10 37.9 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EMC89756.1 - 3.9e-16 57.5 1.6 1.2e-05 25.0 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EMC89756.1 - 7e-16 57.8 2.4 1.5e-08 34.6 0.3 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.25 EMC89756.1 - 1.3e-10 41.2 0.1 6e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMC89756.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Paramyxo_C PF01692.13 EMC89756.1 - 0.078 12.5 5.4 0.16 11.5 3.7 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Aa_trans PF01490.13 EMC89757.1 - 1.2e-16 60.2 30.7 2e-08 33.1 2.4 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMC89757.1 - 2.3e-05 23.4 19.1 0.00055 18.8 1.0 2.6 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family EBP50_C-term PF09007.6 EMC89758.1 - 9.4e-22 76.5 0.3 1.4e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 EBP50, C-terminal PDZ PF00595.19 EMC89758.1 - 5e-15 55.4 0.0 8.3e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC89758.1 - 5.1e-06 26.2 0.1 1.1e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.9 EMC89758.1 - 0.076 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Ras PF00071.17 EMC89759.1 - 5.1e-59 198.2 0.2 6e-59 198.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC89759.1 - 4.4e-18 65.8 0.1 1.3e-17 64.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC89759.1 - 3.9e-14 52.2 0.0 5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMC89759.1 - 4e-07 29.3 0.0 5.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMC89759.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC89759.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 EMC89759.1 - 0.041 12.8 0.1 0.13 11.2 0.1 1.8 1 1 0 1 1 1 0 Septin AAA_24 PF13479.1 EMC89759.1 - 0.074 12.6 0.1 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EMC89759.1 - 0.08 12.2 0.1 0.49 9.6 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DAP3 PF10236.4 EMC89759.1 - 0.08 11.8 0.2 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF1792 PF08759.6 EMC89759.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1792) AAA_22 PF13401.1 EMC89759.1 - 0.13 12.4 0.1 0.99 9.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain V-set PF07686.12 EMC89760.1 - 3.1e-13 49.6 0.5 3.7e-13 49.3 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC89760.1 - 0.0057 16.7 0.6 0.013 15.6 0.4 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC89760.1 - 0.0087 16.1 0.7 0.046 13.8 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 EMC89760.1 - 0.022 15.2 2.9 0.08 13.4 2.0 1.8 1 1 0 1 1 1 0 Immunoglobulin domain FecR PF04773.8 EMC89760.1 - 0.031 14.4 0.4 0.066 13.4 0.1 1.6 2 1 0 2 2 2 0 FecR protein I-set PF07679.11 EMC89760.1 - 0.04 13.7 0.0 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 Immunoglobulin I-set domain V-set PF07686.12 EMC89761.1 - 0.096 12.5 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin V-set domain V-set PF07686.12 EMC89762.1 - 2.9e-06 27.1 0.0 3e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC89762.1 - 0.027 14.5 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain DUF4519 PF15012.1 EMC89763.1 - 4.4 7.2 4.9 3.8 7.4 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4519) Xylo_C PF12529.3 EMC89764.1 - 1.1e-70 236.5 0.0 2.2e-70 235.6 0.0 1.5 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.16 EMC89764.1 - 1.2e-53 181.7 1.8 1.7e-53 181.2 1.2 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ribosomal_L27 PF01016.14 EMC89765.1 - 5.2e-29 99.8 0.1 6.6e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Catalase-rel PF06628.7 EMC89766.1 - 0.061 13.1 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Catalase-related immune-responsive LRR_8 PF13855.1 EMC89767.1 - 1.9e-13 49.9 17.5 2.2e-09 36.8 4.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMC89767.1 - 2.7e-11 41.8 18.5 0.021 14.8 0.4 5.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 EMC89767.1 - 4.3e-11 42.1 15.7 2.7e-07 30.0 1.6 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMC89767.1 - 4.5e-06 25.9 22.8 0.33 11.3 0.9 6.3 6 0 0 6 6 6 2 Leucine rich repeat DUF572 PF04502.8 EMC89767.1 - 0.0046 16.2 18.9 0.0065 15.7 13.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) LMBR1 PF04791.11 EMC89767.1 - 0.035 12.6 2.1 0.044 12.3 1.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GAGA_bind PF06217.7 EMC89767.1 - 0.14 12.1 10.1 0.18 11.7 7.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family LRR_6 PF13516.1 EMC89767.1 - 0.31 11.2 18.1 2.8 8.3 0.0 5.8 5 1 1 6 6 6 0 Leucine Rich repeat Ycf1 PF05758.7 EMC89767.1 - 0.33 8.6 9.8 0.39 8.3 6.8 1.1 1 0 0 1 1 1 0 Ycf1 FUSC PF04632.7 EMC89767.1 - 0.39 9.0 2.4 0.58 8.5 1.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec62 PF03839.11 EMC89767.1 - 0.46 9.8 11.2 0.68 9.3 7.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MIP-T3 PF10243.4 EMC89767.1 - 0.56 8.6 29.6 0.76 8.1 20.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 EMC89767.1 - 1.5 8.1 35.8 2.1 7.6 24.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2413 PF10310.4 EMC89767.1 - 2.1 7.1 16.0 2.6 6.7 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1675 PF07897.6 EMC89767.1 - 3.2 7.5 13.9 4.6 7.0 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDHD PF02862.12 EMC89767.1 - 5.2 6.7 10.6 7.5 6.2 7.4 1.2 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.6 EMC89767.1 - 5.3 5.1 21.7 6.7 4.8 15.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.14 EMC89767.1 - 6 4.5 9.6 8.1 4.1 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.11 EMC89767.1 - 6.3 6.6 7.3 9.8 5.9 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Prog_receptor PF02161.10 EMC89767.1 - 6.6 5.4 9.6 8.8 5.0 6.7 1.1 1 0 0 1 1 1 0 Progesterone receptor Asp-B-Hydro_N PF05279.6 EMC89767.1 - 8.8 6.0 17.6 13 5.5 12.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AMP-binding PF00501.23 EMC89768.1 - 3e-99 332.2 0.0 3.6e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMC89768.1 - 1.1e-15 58.3 0.1 3e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_8 PF13855.1 EMC89769.1 - 6.3e-42 141.1 16.9 5.3e-12 45.3 0.3 5.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EMC89769.1 - 1.3e-22 78.9 26.8 4e-06 26.2 0.1 6.7 1 1 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC89769.1 - 2.3e-19 66.4 19.3 0.012 15.5 0.0 11.4 12 1 0 12 12 12 5 Leucine Rich Repeat LRR_5 PF13306.1 EMC89769.1 - 1.9e-14 53.4 0.0 5.1e-06 26.2 0.0 2.7 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRRNT PF01462.13 EMC89769.1 - 1.2e-07 30.9 4.3 1.2e-07 30.9 3.0 2.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 EMC89769.1 - 1.6e-07 30.6 16.4 9.6 6.6 0.0 9.8 11 0 0 11 11 11 2 Leucine Rich repeat LRR_9 PF14580.1 EMC89769.1 - 0.00013 21.5 2.8 0.034 13.7 0.0 3.3 1 1 2 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 EMC89769.1 - 0.00014 21.5 23.1 25 5.6 0.0 10.0 10 0 0 10 10 10 0 Leucine rich repeat LRR_2 PF07723.8 EMC89769.1 - 1.9 9.0 9.0 13 6.4 0.0 5.9 8 0 0 8 8 8 0 Leucine Rich Repeat Radical_SAM PF04055.16 EMC89770.1 - 9.4e-15 55.1 0.0 5.2e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily HemN_C PF06969.11 EMC89770.1 - 7.9e-07 29.0 0.3 2.1e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 HemN C-terminal domain Thioredox_DsbH PF03190.10 EMC89771.1 - 1.9e-72 242.2 0.0 3.3e-72 241.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EMC89771.1 - 1.7e-11 43.9 0.0 3.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMC89771.1 - 0.00042 20.4 0.1 0.00093 19.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain C5-epim_C PF06662.8 EMC89771.1 - 0.007 15.6 0.5 0.22 10.7 0.1 2.4 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 EMC89771.1 - 0.055 12.5 0.2 1 8.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 ABC_membrane PF00664.18 EMC89772.1 - 1.4e-85 287.0 30.6 1.3e-43 149.4 5.0 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMC89772.1 - 7.1e-55 185.0 0.2 2.5e-29 102.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMC89772.1 - 6.4e-10 38.6 0.0 0.00096 18.4 0.0 4.0 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMC89772.1 - 9.7e-06 25.6 0.5 0.01 15.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EMC89772.1 - 3.9e-05 23.5 0.3 0.072 13.0 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMC89772.1 - 6.7e-05 22.1 1.0 0.015 14.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EMC89772.1 - 9.1e-05 22.9 0.3 0.033 14.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 EMC89772.1 - 0.0013 18.1 3.3 0.087 12.2 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMC89772.1 - 0.0026 17.2 1.0 1 8.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EMC89772.1 - 0.0056 16.5 0.7 0.12 12.1 0.0 2.8 3 0 0 3 3 2 1 Dynamin family GTP_EFTU PF00009.22 EMC89772.1 - 0.0095 15.3 0.1 0.26 10.7 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 EMC89772.1 - 0.016 15.5 3.4 2.7 8.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.8 EMC89772.1 - 0.054 12.4 1.2 0.85 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EMC89772.1 - 0.12 12.5 0.1 9 6.5 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EMC89772.1 - 0.18 10.9 1.1 3.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 EMC89772.1 - 0.22 11.6 2.1 14 5.8 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EMC89772.1 - 0.22 11.2 5.4 2.7 7.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 EMC89772.1 - 0.26 10.9 1.7 3.2 7.4 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 EMC89772.1 - 0.3 9.6 0.5 3.4 6.1 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_17 PF13207.1 EMC89772.1 - 0.58 10.9 6.7 3.7 8.3 0.0 3.5 4 0 0 4 4 2 0 AAA domain Ank PF00023.25 EMC89773.1 - 1.8e-08 33.7 0.1 3.4e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EMC89773.1 - 2.4e-06 27.2 0.1 5.7e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EMC89773.1 - 5.8e-06 26.3 0.2 1.4e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC89773.1 - 0.00013 22.2 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC89773.1 - 0.015 15.8 0.1 0.029 14.8 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) FlbD PF06289.6 EMC89774.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein (FlbD) Kunitz_BPTI PF00014.18 EMC89775.1 - 6.3e-34 115.9 31.9 2.8e-21 75.4 4.9 3.4 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.11 EMC89775.1 - 7.4e-17 60.9 0.0 1.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain NTR PF01759.16 EMC89775.1 - 2.9e-11 42.8 0.0 7.4e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Ig_2 PF13895.1 EMC89775.1 - 2.2e-10 40.5 0.0 7.2e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 EMC89775.1 - 1.5e-07 31.2 0.0 4.3e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain WAP PF00095.16 EMC89775.1 - 5.1e-07 29.5 11.2 5.1e-07 29.5 7.7 4.3 4 1 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ig_3 PF13927.1 EMC89775.1 - 7.4e-07 29.5 0.1 2e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.10 EMC89775.1 - 4.1e-06 26.6 2.9 4.1e-06 26.6 2.0 2.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain ig PF00047.20 EMC89775.1 - 6e-05 23.0 0.3 0.00031 20.8 0.2 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Porphobil_deam PF01379.15 EMC89775.1 - 0.05 12.5 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain BTG PF07742.7 EMC89776.1 - 3.8e-42 142.5 0.0 6.3e-42 141.8 0.0 1.3 1 0 0 1 1 1 1 BTG family PAM2 PF07145.10 EMC89776.1 - 7.8e-07 28.1 3.3 0.0025 17.2 0.2 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Jnk-SapK_ap_N PF09744.4 EMC89777.1 - 1.9e-26 92.9 13.6 1.9e-26 92.9 9.4 3.6 4 1 0 4 4 4 1 JNK_SAPK-associated protein-1 Sipho_Gp157 PF05565.6 EMC89777.1 - 0.0024 17.4 3.8 0.0024 17.4 2.6 2.7 2 0 0 2 2 2 1 Siphovirus Gp157 IncA PF04156.9 EMC89777.1 - 0.035 13.7 33.2 0.14 11.7 5.8 4.4 4 0 0 4 4 4 0 IncA protein DUF972 PF06156.8 EMC89777.1 - 0.2 12.0 31.7 0.55 10.6 4.6 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Prominin PF05478.6 EMC89777.1 - 3.8 4.9 10.5 0.21 9.0 0.7 2.3 2 0 0 2 2 2 0 Prominin NDK PF00334.14 EMC89778.1 - 1.5e-100 332.4 0.0 1.5e-56 189.9 0.0 2.0 2 0 0 2 2 2 2 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EMC89778.1 - 0.0005 19.7 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Photosystem I reaction centre subunit IX / PsaJ MarR PF01047.17 EMC89778.1 - 0.011 15.3 0.0 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 MarR family Elong-fact-P_C PF09285.6 EMC89778.1 - 0.089 12.1 0.0 5.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor P, C-terminal MBT PF02820.13 EMC89779.1 - 2e-88 290.3 2.4 2.6e-30 104.1 0.1 4.5 4 0 0 4 4 4 4 mbt repeat WD40 PF00400.27 EMC89780.1 - 7e-12 44.7 0.1 0.43 10.5 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMC89780.1 - 0.044 13.2 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Carb_anhydrase PF00194.16 EMC89781.1 - 1e-54 185.2 0.0 1.2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1647 PF07801.6 EMC89781.1 - 0.072 12.5 0.3 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) GAT PF03127.9 EMC89782.1 - 1.8e-25 88.7 2.9 3.1e-25 88.0 2.0 1.4 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EMC89782.1 - 1.4e-18 66.8 0.2 2.6e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 VHS domain DUF4611 PF15387.1 EMC89782.1 - 0.048 13.8 0.1 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CtaG_Cox11 PF04442.9 EMC89783.1 - 1.7e-41 141.5 2.0 2.1e-41 141.2 1.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 WW PF00397.21 EMC89784.1 - 9.5e-11 41.3 0.6 1.6e-10 40.6 0.4 1.4 1 0 0 1 1 1 1 WW domain PDZ PF00595.19 EMC89784.1 - 1.4e-10 41.1 0.2 4.6e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) TPR_MLP1_2 PF07926.7 EMC89784.1 - 0.0058 16.3 13.1 0.0058 16.3 9.1 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein PDZ_2 PF13180.1 EMC89784.1 - 0.024 14.5 0.0 0.097 12.5 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Pox_A11 PF05061.8 EMC89784.1 - 0.039 13.0 4.1 0.065 12.3 2.8 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein MAD PF05557.8 EMC89784.1 - 0.11 10.5 18.9 0.023 12.8 10.3 1.7 2 0 0 2 2 2 0 Mitotic checkpoint protein DivIVA PF05103.8 EMC89784.1 - 0.21 11.6 16.8 0.44 10.5 10.8 2.2 2 1 1 3 3 3 0 DivIVA protein Rota_NSP4 PF01452.11 EMC89784.1 - 0.23 10.7 2.5 0.48 9.7 1.7 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein Seryl_tRNA_N PF02403.17 EMC89784.1 - 0.42 10.6 17.2 0.2 11.7 7.1 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EMC89784.1 - 0.42 10.4 9.3 0.16 11.7 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.11 EMC89784.1 - 0.43 9.1 4.0 0.6 8.6 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.6 EMC89784.1 - 6.3 6.7 8.1 13 5.6 0.1 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EMC89784.1 - 9.8 6.2 13.3 2.5 8.2 6.8 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.10 EMC89785.1 - 1.9e-17 62.7 12.6 3.7e-17 61.8 8.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC89785.1 - 0.00023 21.0 10.0 0.00045 20.1 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.6 EMC89785.1 - 0.012 15.2 0.4 0.022 14.4 0.3 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.12 EMC89785.1 - 0.025 14.8 8.0 0.029 14.6 4.9 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.13 EMC89785.1 - 0.059 13.0 0.5 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EMC89785.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HlyIII PF03006.15 EMC89786.1 - 2.5e-44 151.3 22.1 2.8e-44 151.1 15.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related Meckelin PF09773.4 EMC89786.1 - 0.11 10.2 2.9 0.14 9.8 2.0 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) PIRT PF15099.1 EMC89787.1 - 8.4e-62 206.1 0.7 9.3e-62 205.9 0.5 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Claudin_2 PF13903.1 EMC89787.1 - 6.6e-05 22.6 0.2 7.3e-05 22.5 0.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Neurensin PF14927.1 EMC89787.1 - 0.00056 19.3 3.0 0.077 12.3 0.0 2.1 1 1 1 2 2 2 2 Neurensin IncA PF04156.9 EMC89787.1 - 0.00099 18.7 1.4 0.0012 18.4 1.0 1.1 1 0 0 1 1 1 1 IncA protein NfeD PF01957.13 EMC89787.1 - 0.0013 18.8 0.3 0.0017 18.5 0.2 1.1 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 EMC89787.1 - 0.0021 17.5 0.2 0.0028 17.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) UPF0542 PF15086.1 EMC89787.1 - 0.012 15.3 0.1 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF373 PF04123.8 EMC89787.1 - 0.044 12.8 0.2 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TMEM51 PF15345.1 EMC89787.1 - 0.08 12.6 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3040 PF11239.3 EMC89787.1 - 0.16 12.0 2.7 0.27 11.2 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) P12 PF12669.2 EMC89787.1 - 1.6 8.9 4.1 30 4.8 0.1 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family START PF01852.14 EMC89788.1 - 1.9e-30 105.7 0.0 2.3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EMC89788.1 - 0.0073 15.9 0.1 0.024 14.2 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Ten1_2 PF15490.1 EMC89789.1 - 3.7e-40 136.1 0.0 4.1e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF960 PF06124.6 EMC89789.1 - 0.074 13.2 0.0 0.091 13.0 0.0 1.2 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) Spectrin PF00435.16 EMC89790.1 - 0.00099 19.3 7.3 0.0028 17.8 1.6 12.1 9 3 3 12 12 12 4 Spectrin repeat TPR_6 PF13174.1 EMC89791.1 - 0.00076 19.7 2.6 1.7 9.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC89791.1 - 0.038 13.6 3.5 0.8 9.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC89791.1 - 0.18 11.4 4.2 3.5 7.3 0.5 3.2 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 EMC89791.1 - 0.25 11.3 10.5 0.72 9.8 0.1 3.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC89791.1 - 0.27 11.2 11.6 0.4 10.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat 7tm_1 PF00001.16 EMC89792.1 - 1.2e-60 204.8 23.5 1.5e-60 204.5 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 EMC89792.1 - 1.7e-13 50.3 18.9 4.2e-12 45.8 13.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 EMC89792.1 - 2.6e-11 43.1 21.5 3.3e-11 42.8 14.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC89792.1 - 7.1e-07 28.6 20.5 9.9e-07 28.1 14.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 EMC89792.1 - 3.4e-05 23.0 18.5 3.4e-05 23.0 12.8 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SecG PF03840.9 EMC89792.1 - 0.022 14.4 2.7 0.66 9.7 0.0 3.3 3 0 0 3 3 3 0 Preprotein translocase SecG subunit Flavi_capsid PF01003.14 EMC89792.1 - 0.11 11.9 0.1 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Flavivirus capsid protein C Git3_C PF11970.3 EMC89792.1 - 0.29 10.9 5.1 0.53 10.0 1.1 2.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3493 PF11998.3 EMC89792.1 - 1.5 8.7 3.9 2.9 7.8 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) Herpes_US9 PF06072.6 EMC89792.1 - 2 8.3 5.0 0.64 9.8 0.2 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Exo70 PF03081.10 EMC89793.1 - 4.9e-81 272.3 3.9 4.9e-81 272.3 2.7 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit GIT1_C PF12205.3 EMC89793.1 - 0.0063 16.3 0.3 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term COG5 PF10392.4 EMC89793.1 - 0.019 14.8 0.7 0.019 14.8 0.5 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Scaffolding_pro PF11418.3 EMC89793.1 - 0.024 14.9 1.2 0.57 10.5 0.1 3.4 3 0 0 3 3 3 0 Phi29 scaffolding protein FlaC_arch PF05377.6 EMC89793.1 - 0.23 11.4 2.4 16 5.5 0.3 3.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF148 PF02520.12 EMC89793.1 - 0.35 10.6 4.6 0.16 11.7 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF148 Poty_PP PF08440.5 EMC89793.1 - 1.3 8.0 6.8 0.38 9.7 0.7 2.5 3 0 0 3 3 3 0 Potyviridae polyprotein BAG PF02179.11 EMC89793.1 - 5.4 7.2 9.2 32 4.7 0.0 4.6 6 0 0 6 6 6 0 BAG domain Fork_head PF00250.13 EMC89794.1 - 8.4e-39 131.5 0.1 1.9e-38 130.3 0.1 1.6 1 0 0 1 1 1 1 Fork head domain zf-C3HC4_3 PF13920.1 EMC89795.1 - 4.2e-14 51.9 9.2 8.3e-14 51.0 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC89795.1 - 2.9e-07 30.3 12.3 6.4e-07 29.2 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC89795.1 - 5e-05 23.0 12.0 0.00012 21.7 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMC89795.1 - 0.0011 18.6 10.2 0.0029 17.2 7.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EMC89795.1 - 0.01 15.3 6.4 0.025 14.1 4.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EMC89795.1 - 0.6 9.7 7.9 1.5 8.4 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EMC89795.1 - 1.8 8.0 11.5 2 7.9 6.7 2.2 2 0 0 2 2 2 0 P-11 zinc finger V-set PF07686.12 EMC89797.1 - 0.0011 18.9 0.3 0.0058 16.5 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain TB2_DP1_HVA22 PF03134.14 EMC89797.1 - 0.045 13.4 0.5 0.063 13.0 0.4 1.2 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Permease PF02405.11 EMC89797.1 - 0.078 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Permease Septin PF00735.13 EMC89798.1 - 3.4e-111 370.7 2.5 4.2e-111 370.4 1.7 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMC89798.1 - 4.5e-09 36.2 0.7 1.7e-08 34.4 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC89798.1 - 9.4e-07 28.1 0.0 1.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMC89798.1 - 1.9e-05 24.5 2.0 0.0041 16.9 0.4 2.5 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.11 EMC89798.1 - 3.7e-05 22.9 0.1 6.1e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EMC89798.1 - 4.5e-05 22.9 0.9 0.00014 21.3 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EMC89798.1 - 0.00012 22.4 0.1 0.0069 16.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EMC89798.1 - 0.00019 21.8 0.1 0.00045 20.6 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMC89798.1 - 0.00037 19.9 0.0 0.00095 18.5 0.0 1.7 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMC89798.1 - 0.002 16.8 0.8 0.0033 16.1 0.0 1.9 2 1 0 2 2 2 1 G-protein alpha subunit AAA_10 PF12846.2 EMC89798.1 - 0.0031 16.9 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EMC89798.1 - 0.0032 16.9 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EMC89798.1 - 0.0062 15.4 0.1 0.041 12.6 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 EMC89798.1 - 0.0091 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC89798.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EMC89798.1 - 0.019 14.4 0.3 0.18 11.2 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EMC89798.1 - 0.028 13.5 0.2 0.077 12.1 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EMC89798.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EMC89798.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EMC89798.1 - 0.062 13.0 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_32 PF13654.1 EMC89798.1 - 0.079 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMC89798.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EMC89798.1 - 0.09 12.0 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family NB-ARC PF00931.17 EMC89798.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EMC89798.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMC89798.1 - 0.14 11.4 0.1 0.34 10.1 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B M_domain PF12938.2 EMC89799.1 - 2.4e-46 158.4 32.9 2.4e-46 158.4 22.8 9.5 6 3 3 11 11 11 1 M domain of GW182 Ago_hook PF10427.4 EMC89799.1 - 2.6e-18 66.4 24.6 2.6e-18 66.4 17.1 11.9 6 1 5 12 12 12 1 Argonaute hook UBA PF00627.26 EMC89799.1 - 1.2e-06 28.1 0.1 2.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RRM_5 PF13893.1 EMC89799.1 - 2.8e-06 27.0 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC89799.1 - 0.00029 20.4 0.0 0.00049 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89799.1 - 0.001 18.9 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) THOC7 PF05615.8 EMC89799.1 - 0.22 11.7 3.6 0.38 11.0 2.5 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Ras PF00071.17 EMC89800.1 - 1.2e-33 115.8 0.0 4.6e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMC89800.1 - 5.3e-20 72.0 0.0 7.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC89800.1 - 1.1e-07 31.3 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMC89800.1 - 7.1e-06 25.3 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMC89800.1 - 2.2e-05 23.9 0.0 0.0019 17.6 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC89800.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC89800.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMC89800.1 - 0.0016 18.5 0.0 0.0099 16.0 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMC89800.1 - 0.0038 17.2 0.2 0.015 15.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EMC89800.1 - 0.0073 16.0 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase Gtr1_RagA PF04670.7 EMC89800.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMC89800.1 - 0.017 13.8 0.0 0.02 13.6 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit Viral_helicase1 PF01443.13 EMC89800.1 - 0.035 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EMC89800.1 - 0.04 13.5 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EMC89800.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EMC89800.1 - 0.061 13.0 0.0 0.091 12.4 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EMC89800.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Guanylin PF02058.10 EMC89800.1 - 0.16 12.0 0.8 0.48 10.5 0.2 2.0 2 0 0 2 2 2 0 Guanylin precursor PRELI PF04707.9 EMC89801.1 - 2.7e-46 156.9 1.2 4.1e-46 156.3 0.8 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.15 EMC89801.1 - 2.1e-41 141.0 0.0 3.6e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMC89801.1 - 8.7e-09 35.3 0.3 7.8e-08 32.3 0.1 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMC89801.1 - 0.0023 17.8 0.0 0.025 14.4 0.0 2.4 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain Phage_fiber_2 PF03406.8 EMC89801.1 - 0.24 11.0 1.6 0.53 9.9 1.1 1.5 1 0 0 1 1 1 0 Phage tail fibre repeat Glyco_transf_18 PF15024.1 EMC89802.1 - 2.4e-220 732.6 0.2 1.4e-219 730.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 18 UNC-93 PF05978.11 EMC89803.1 - 1.1e-49 167.9 15.2 1.1e-49 167.9 10.5 3.3 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EMC89803.1 - 3.7e-12 45.6 38.7 3.4e-10 39.1 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3139 PF11337.3 EMC89803.1 - 4.8 7.5 7.2 35 4.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3139) RRM_1 PF00076.17 EMC89804.1 - 6.9e-20 70.4 0.0 9.6e-20 69.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC89804.1 - 4.3e-14 52.2 0.0 5.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC89804.1 - 3.7e-08 33.0 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC89804.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMC89804.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Methyltransf_16 PF10294.4 EMC89806.1 - 1.2e-17 63.9 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMC89806.1 - 0.002 18.7 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC89806.1 - 0.069 12.8 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMC89806.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PMT_C PF11647.3 EMC89807.1 - 0.064 12.8 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 DUF3782 PF12644.2 EMC89807.1 - 0.083 12.6 0.5 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Glyco_transf_29 PF00777.13 EMC89808.1 - 6.6e-69 232.0 0.0 9.1e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_29 PF00777.13 EMC89809.1 - 1.8e-64 217.4 0.0 2.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Globin PF00042.17 EMC89810.1 - 1.8e-25 89.4 0.1 2.7e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Globin Rhomboid_SP PF12595.3 EMC89811.1 - 2.6e-81 272.2 3.4 4.1e-81 271.5 2.3 1.3 1 0 0 1 1 1 1 Rhomboid serine protease Rhomboid PF01694.17 EMC89811.1 - 8.3e-11 42.1 0.3 8.3e-11 42.1 0.2 1.7 2 0 0 2 2 2 1 Rhomboid family Acetyltransf_1 PF00583.19 EMC89812.1 - 1.1e-12 47.7 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMC89812.1 - 4.3e-07 29.9 0.0 7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMC89812.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DAGK_cat PF00781.19 EMC89813.1 - 3e-27 94.6 0.0 4.4e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pribosyl_synth PF14572.1 EMC89814.1 - 1.4e-102 341.1 0.8 1.4e-102 341.1 0.6 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMC89814.1 - 3.7e-37 126.5 0.2 7.7e-37 125.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMC89814.1 - 0.00018 21.2 2.6 0.0011 18.6 1.2 2.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Viral_env_E26 PF11050.3 EMC89814.1 - 0.12 11.5 0.1 0.27 10.3 0.1 1.5 1 0 0 1 1 1 0 Virus envelope protein E26 Img2 PF05046.9 EMC89815.1 - 0.0094 16.1 1.4 0.036 14.2 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) GLTSCR1 PF15249.1 EMC89815.1 - 0.039 14.0 2.5 1.7 8.8 0.0 3.2 3 1 0 3 3 3 0 Glioma tumor suppressor candidate region Bac_GDH PF05088.7 EMC89815.1 - 0.27 8.5 3.6 0.096 10.0 0.2 1.7 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase DUF4315 PF14193.1 EMC89815.1 - 6.4 6.7 8.1 0.5 10.3 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Synaptobrevin PF00957.16 EMC89815.1 - 9 5.9 6.5 4.8 6.8 0.1 2.9 3 0 0 3 3 3 0 Synaptobrevin 7tm_1 PF00001.16 EMC89816.1 - 4.7e-49 166.8 24.6 6.4e-49 166.4 17.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC89817.1 - 2.6e-19 69.3 5.0 3e-19 69.1 3.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC89817.1 - 0.00018 20.7 2.0 0.00023 20.3 1.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 EMC89817.1 - 0.00077 18.6 1.9 0.0011 18.1 1.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Anticodon_1 PF08264.8 EMC89817.1 - 0.034 13.8 0.4 0.073 12.8 0.2 1.6 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA DUF1129 PF06570.6 EMC89817.1 - 0.051 12.8 0.3 0.081 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 2OG-FeII_Oxy_4 PF13661.1 EMC89818.1 - 5.4e-12 45.1 0.9 1.2e-11 44.0 0.6 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMC89818.1 - 1.8e-08 34.8 0.1 3.5e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TetR_N PF00440.18 EMC89818.1 - 0.14 11.8 0.3 18 5.1 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Glyco_hydro_20 PF00728.17 EMC89819.1 - 9.4e-12 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF3279 PF11682.3 EMC89819.1 - 0.031 13.8 0.1 0.13 11.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) DUF4564 PF15169.1 EMC89820.1 - 1.4e-83 279.3 0.0 1.5e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) UbiA PF01040.13 EMC89820.1 - 0.032 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Fe_hyd_lg_C PF02906.9 EMC89821.1 - 7.2e-77 258.4 0.2 1.1e-75 254.5 0.1 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 EMC89821.1 - 5.5e-11 42.3 1.0 1.1e-10 41.3 0.1 1.9 2 0 0 2 2 2 1 Iron hydrogenase small subunit Fork_head PF00250.13 EMC89823.1 - 4.8e-41 138.7 0.2 7.8e-41 138.0 0.2 1.4 1 0 0 1 1 1 1 Fork head domain WD40 PF00400.27 EMC89825.1 - 3.4e-06 26.7 1.0 0.1 12.5 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3761 PF12587.3 EMC89825.1 - 0.0023 18.0 0.1 0.0052 16.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3761) Me-amine-dh_H PF06433.6 EMC89825.1 - 0.033 12.8 0.2 4.8 5.7 0.1 2.4 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) CPSF_A PF03178.10 EMC89825.1 - 0.047 12.7 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region DUF1513 PF07433.6 EMC89825.1 - 0.13 11.1 0.0 0.34 9.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) Ras PF00071.17 EMC89826.1 - 7e-41 139.3 0.0 9.9e-41 138.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC89826.1 - 9.2e-13 48.7 0.0 1.4e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SOCS_box PF07525.11 EMC89826.1 - 1.1e-07 31.5 2.0 1.8e-07 30.8 1.0 1.7 2 0 0 2 2 2 1 SOCS box Arf PF00025.16 EMC89826.1 - 4e-06 26.1 0.0 5.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Fructosamin_kin PF03881.9 EMC89827.1 - 1.4e-69 234.3 0.1 3.8e-69 232.8 0.1 1.6 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMC89827.1 - 7e-09 35.7 0.0 9.2e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family CENP-Q PF13094.1 EMC89827.1 - 0.013 15.5 0.2 0.029 14.4 0.0 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RIO1 PF01163.17 EMC89827.1 - 0.1 11.9 0.0 3.5 6.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 EMC89828.1 - 1.1e-73 247.7 0.0 2.4e-73 246.6 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMC89828.1 - 1.2e-15 57.8 0.0 1.7e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EMC89828.1 - 0.00038 19.6 0.1 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMC89828.1 - 0.0024 17.2 0.0 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH_6_hur PF04655.9 EMC89828.1 - 0.13 11.4 0.1 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TFCD_C PF12612.3 EMC89829.1 - 1.1e-58 197.8 0.3 1.4e-56 190.9 0.0 3.6 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 EMC89829.1 - 3.5e-06 27.3 13.4 0.29 11.6 0.0 7.4 5 2 1 7 7 7 3 HEAT-like repeat HEAT PF02985.17 EMC89829.1 - 2.6e-05 23.9 3.6 0.15 12.1 0.0 7.2 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.1 EMC89829.1 - 0.0013 18.9 7.0 0.093 13.0 0.3 5.4 4 2 1 5 5 5 1 HEAT repeats HEAT_PBS PF03130.11 EMC89829.1 - 0.32 11.5 5.0 27 5.6 0.0 5.6 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Glycos_transf_2 PF00535.21 EMC89830.1 - 4.9e-21 75.1 0.0 7.6e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EMC89830.1 - 3.8e-09 36.0 0.0 6.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EMC89830.1 - 5.8e-07 29.5 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EMC89830.1 - 1.2e-05 25.5 0.0 0.00094 19.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 TIMP PF00965.12 EMC89832.1 - 0.0035 16.9 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 EMC89832.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Sulfotransfer_1 PF00685.22 EMC89834.1 - 1.1e-31 110.0 0.0 1.4e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 EMC89834.1 - 0.0066 16.1 0.0 0.059 13.0 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family RICTOR_M PF14666.1 EMC89834.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain UbiA PF01040.13 EMC89835.1 - 1.7e-29 102.8 18.3 2.2e-29 102.4 12.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Sulfotransfer_1 PF00685.22 EMC89836.1 - 2.2e-39 135.3 0.0 2.7e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 EMC89836.1 - 0.0092 15.6 0.0 0.068 12.8 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family RICTOR_M PF14666.1 EMC89836.1 - 0.17 10.8 0.1 0.28 10.1 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain PMP22_Claudin PF00822.15 EMC89840.1 - 5.3e-45 153.0 17.0 5.9e-45 152.8 11.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC89840.1 - 3.6e-08 33.2 19.4 3.6e-08 33.2 13.5 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 EMC89840.1 - 0.032 14.2 14.3 0.057 13.4 9.8 1.7 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Amastin PF07344.6 EMC89840.1 - 0.034 13.7 13.1 0.054 13.1 8.8 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_3 PF06653.6 EMC89840.1 - 0.089 12.5 16.4 0.11 12.1 11.4 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF2207 PF09972.4 EMC89840.1 - 0.11 11.0 10.4 0.076 11.5 3.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PepSY_TM PF03929.11 EMC89840.1 - 0.16 12.4 0.1 0.16 12.4 0.1 4.0 4 2 0 4 4 3 0 PepSY-associated TM helix MARVEL PF01284.18 EMC89840.1 - 0.27 11.0 15.3 0.73 9.6 4.5 2.2 2 0 0 2 2 2 0 Membrane-associating domain DUF21 PF01595.15 EMC89840.1 - 0.32 10.2 0.1 0.32 10.2 0.0 2.5 2 2 0 2 2 1 0 Domain of unknown function DUF21 DUF2723 PF11028.3 EMC89840.1 - 0.53 9.7 10.9 0.14 11.6 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2723) DUF373 PF04123.8 EMC89840.1 - 1.1 8.1 9.1 0.49 9.3 2.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF4064 PF13273.1 EMC89840.1 - 3 7.9 13.4 12 6.0 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) 7TMR-DISM_7TM PF07695.6 EMC89840.1 - 3.2 7.3 22.0 18 4.9 14.0 2.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling ABC2_membrane_4 PF12730.2 EMC89840.1 - 5.2 6.1 18.8 53 2.8 13.6 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Tektin PF03148.9 EMC89841.1 - 2.5e-147 490.4 26.0 2.8e-147 490.2 18.0 1.0 1 0 0 1 1 1 1 Tektin family Sin3_corepress PF08295.7 EMC89841.1 - 0.49 10.1 8.3 2.6 7.8 0.1 3.3 3 0 0 3 3 3 0 Sin3 family co-repressor DUF763 PF05559.6 EMC89841.1 - 1.6 7.6 7.5 7.3 5.4 1.3 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF763) DUF2721 PF11026.3 EMC89841.1 - 8.6 6.0 7.9 5.2 6.7 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) DUF846 PF05832.7 EMC89842.1 - 1.1e-54 184.0 9.6 1.2e-54 183.8 6.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM192 PF14802.1 EMC89842.1 - 0.11 11.2 0.6 0.2 10.4 0.4 1.3 1 0 0 1 1 1 0 TMEM192 family PT PF04886.7 EMC89843.1 - 5.9e-06 25.4 29.0 1.4e+03 -1.4 0.3 4.6 2 1 0 2 2 2 0 PT repeat DUF697 PF05128.7 EMC89844.1 - 0.0016 17.9 0.8 0.88 9.0 0.0 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF697) DNA_pol_A_exo1 PF01612.15 EMC89845.1 - 8.9e-23 80.6 0.1 2.9e-22 78.9 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease Mut7-C PF01927.11 EMC89845.1 - 1.6e-14 54.0 0.7 3.5e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Mut7-C RNAse domain C2 PF00168.25 EMC89849.1 - 4.1e-55 183.5 0.6 7.5e-27 93.0 0.2 2.2 2 0 0 2 2 2 2 C2 domain DUF1510 PF07423.6 EMC89849.1 - 0.0025 17.2 0.5 0.0054 16.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) DOCK-C2 PF14429.1 EMC89849.1 - 0.0041 16.7 0.4 0.93 9.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 EMC89849.1 - 0.014 14.9 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain Shisa PF13908.1 EMC89849.1 - 0.067 13.3 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 EMC89849.1 - 0.098 12.2 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 IncA protein Orthopox_F7 PF05813.7 EMC89849.1 - 0.42 10.5 4.8 1 9.3 2.6 2.2 2 0 0 2 2 2 0 Orthopoxvirus F7 protein CLASP_N PF12348.3 EMC89850.1 - 1.5e-43 148.7 10.0 1.4e-38 132.4 0.0 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 EMC89850.1 - 2.4e-10 39.5 6.0 0.078 13.1 0.0 8.2 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EMC89850.1 - 4.9e-08 33.1 6.7 0.027 14.7 0.3 6.6 5 2 2 8 8 7 3 HEAT repeats DUF2435 PF10363.4 EMC89850.1 - 1.8e-06 27.7 2.1 0.074 12.9 0.0 3.8 2 1 1 3 3 3 3 Protein of unknown function (DUF2435) Ipi1_N PF12333.3 EMC89850.1 - 2.3e-06 27.4 1.4 0.008 16.1 0.0 3.5 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EMC89850.1 - 0.00011 22.5 0.1 0.33 11.5 0.0 4.9 4 0 0 4 4 4 1 HEAT-like repeat ParcG PF10274.4 EMC89850.1 - 0.00017 21.5 2.2 0.0017 18.2 0.0 2.9 2 1 1 3 3 3 1 Parkin co-regulated protein Cnd1 PF12717.2 EMC89850.1 - 0.00045 20.1 4.2 0.00098 19.0 0.3 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EMC89850.1 - 0.0013 19.0 1.0 16 5.9 0.0 4.6 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region TAN PF11640.3 EMC89850.1 - 0.0097 15.6 3.3 0.049 13.3 0.1 3.3 2 1 1 3 3 3 1 Telomere-length maintenance and DNA damage repair Sec7_N PF12783.2 EMC89850.1 - 0.015 14.7 6.1 2.4 7.5 0.0 3.8 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal MMS19_N PF14500.1 EMC89850.1 - 0.039 13.2 2.1 5 6.3 0.0 3.6 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EMC89850.1 - 0.45 9.1 9.5 0.05 12.3 0.2 3.4 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal LRR_6 PF13516.1 EMC89851.1 - 4.8e-19 66.2 35.8 0.00028 20.6 0.0 11.0 11 0 0 11 11 11 6 Leucine Rich repeat F-box-like PF12937.2 EMC89851.1 - 1.7e-13 50.0 0.4 8.8e-13 47.7 0.3 2.3 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EMC89851.1 - 2.2e-13 49.4 21.2 0.0022 17.5 0.4 6.7 4 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC89851.1 - 6.2e-11 41.8 28.6 0.00024 20.8 1.1 6.1 2 1 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EMC89851.1 - 8.3e-11 40.3 31.1 0.45 10.7 0.0 11.4 11 1 0 11 11 11 5 Leucine Rich Repeat F-box PF00646.28 EMC89851.1 - 3.1e-08 33.0 1.9 8.7e-08 31.6 0.4 2.6 2 0 0 2 2 2 1 F-box domain LRR_7 PF13504.1 EMC89851.1 - 0.011 15.8 34.6 5.6 7.6 0.1 10.7 9 2 0 9 9 9 0 Leucine rich repeat Mating_N PF12731.2 EMC89851.1 - 0.043 13.6 0.1 1.4 8.7 0.0 2.6 1 1 0 2 2 2 0 Mating-type protein beta 1 Xlink PF00193.12 EMC89852.1 - 3.2e-08 33.5 0.1 6.8e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Extracellular link domain Sushi PF00084.15 EMC89852.1 - 5.4e-06 26.6 0.6 5.4e-06 26.6 0.4 2.1 2 0 0 2 2 2 1 Sushi domain (SCR repeat) SIT PF15330.1 EMC89852.1 - 0.008 16.3 0.9 0.022 14.9 0.1 2.1 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT MLANA PF14991.1 EMC89852.1 - 0.02 14.8 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein melan-A Ly49 PF08391.5 EMC89852.1 - 0.031 14.4 0.3 0.07 13.2 0.2 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region GAPT PF11770.3 EMC89852.1 - 0.074 12.7 0.2 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) P12 PF12669.2 EMC89852.1 - 0.081 13.1 0.1 0.081 13.1 0.1 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF3377 PF11857.3 EMC89852.1 - 0.1 12.2 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) YfiO PF13525.1 EMC89853.1 - 0.048 13.1 0.6 0.048 13.1 0.4 2.5 2 1 0 2 2 2 0 Outer membrane lipoprotein TPR_14 PF13428.1 EMC89853.1 - 0.049 14.2 0.2 0.18 12.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_18 PF13512.1 EMC89853.1 - 0.5 10.3 6.8 0.23 11.4 0.2 2.9 2 2 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC89853.1 - 2.4 8.0 5.6 9.6 6.1 0.2 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat LSM PF01423.17 EMC89854.1 - 9e-19 66.8 0.5 1e-18 66.6 0.3 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 EMC89854.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain Ribosomal_L32p PF01783.18 EMC89855.1 - 4.1e-09 36.4 6.9 5.6e-09 36.0 4.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.10 EMC89855.1 - 0.0005 19.4 0.6 0.00092 18.6 0.4 1.4 1 0 0 1 1 1 1 RecR protein DZR PF12773.2 EMC89855.1 - 0.0096 15.7 2.2 0.019 14.7 1.5 1.5 1 1 0 1 1 1 1 Double zinc ribbon NRDD PF13597.1 EMC89855.1 - 0.067 11.2 1.3 0.073 11.1 0.9 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase PolC_DP2 PF03833.8 EMC89855.1 - 0.07 10.7 0.4 0.075 10.6 0.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 A2L_zn_ribbon PF08792.5 EMC89855.1 - 0.19 11.2 1.7 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Proteasome PF00227.21 EMC89856.1 - 2.5e-59 199.7 0.0 3.8e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMC89856.1 - 3.1e-11 42.3 0.1 5.4e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.10 EMC89856.1 - 0.016 15.2 0.0 2.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain DUF1308 PF07000.6 EMC89857.1 - 9.4e-119 396.2 0.0 1.1e-118 396.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Trypan_PARP PF05887.6 EMC89858.1 - 2.1 8.1 9.4 2.2 8.0 6.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C2H2 PF00096.21 EMC89859.1 - 1.2e-18 66.1 30.2 0.00064 19.9 0.3 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC89859.1 - 2.8e-15 55.7 30.7 3.2e-07 30.2 1.0 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC89859.1 - 2.7e-08 33.5 29.6 0.022 15.0 0.1 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger DUF2454 PF10521.4 EMC89861.1 - 0.071 12.0 0.0 0.071 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) TGF_beta PF00019.15 EMC89862.1 - 1.1e-37 128.4 1.3 2.1e-37 127.5 0.9 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 EMC89862.1 - 8.8e-18 64.4 0.1 1.7e-17 63.5 0.1 1.4 1 1 0 1 1 1 1 TGF-beta propeptide Hs1pro-1_N PF07231.7 EMC89863.1 - 0.044 13.3 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Hs1pro-1 N-terminus CoA_transf_3 PF02515.12 EMC89864.1 - 1.6e-48 164.5 0.1 1.8e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III Pkinase PF00069.20 EMC89866.1 - 2e-73 246.7 0.0 3.7e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89866.1 - 6.3e-36 123.7 0.0 1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC89866.1 - 1.9e-05 23.7 0.1 0.00019 20.4 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC89866.1 - 0.014 14.5 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC89866.1 - 0.1 12.3 0.2 7.4 6.2 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family PDEase_I PF00233.14 EMC89868.1 - 9.9e-93 310.2 17.6 1.1e-91 306.8 11.5 2.6 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 EMC89868.1 - 4e-27 93.8 0.0 8.1e-27 92.8 0.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal FAA_hydrolase_N PF09298.6 EMC89868.1 - 0.024 14.6 0.4 0.091 12.7 0.1 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal MDFI PF15316.1 EMC89869.1 - 4.3e-17 62.6 14.6 6e-17 62.1 10.1 1.2 1 0 0 1 1 1 1 MyoD family inhibitor Methyltransf_3 PF01596.12 EMC89870.1 - 4e-30 104.4 0.1 7.1e-30 103.5 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase adh_short PF00106.20 EMC89870.1 - 1.9e-29 102.7 2.6 1.1e-28 100.1 1.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMC89870.1 - 4e-23 82.4 0.1 6.8e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMC89870.1 - 1.5e-10 41.0 1.8 2.7e-10 40.2 0.5 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_24 PF13578.1 EMC89870.1 - 5.8e-05 23.8 0.1 0.00019 22.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 EMC89870.1 - 0.0019 16.9 1.0 0.46 9.1 0.1 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EMC89870.1 - 0.069 13.5 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain HTH_6 PF01418.12 EMC89870.1 - 0.069 12.8 0.2 0.96 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DHQ_synthase PF01761.15 EMC89871.1 - 1.5e-57 194.4 0.0 1.9e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EMC89871.1 - 6.6e-15 55.1 0.0 1.4e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EMC89871.1 - 4.4e-06 25.5 0.0 7.7e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF3371 PF11851.3 EMC89872.1 - 4.8e-46 156.7 0.9 4.8e-46 156.7 0.6 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3371) HLH PF00010.21 EMC89872.1 - 2e-16 59.3 0.5 2e-16 59.3 0.4 2.0 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain 5-FTHF_cyc-lig PF01812.15 EMC89872.1 - 0.05 13.3 6.3 0.18 11.5 0.5 2.3 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family Ribophorin_I PF04597.9 EMC89872.1 - 0.23 9.9 4.6 0.37 9.2 3.2 1.2 1 0 0 1 1 1 0 Ribophorin I DUF4034 PF13226.1 EMC89872.1 - 0.47 9.5 4.3 0.83 8.6 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4034) 7tm_4 PF13853.1 EMC89873.1 - 6.2e-46 155.7 8.9 7.2e-46 155.5 6.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 EMC89873.1 - 0.00019 20.6 5.6 0.00024 20.3 3.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2269 PF10027.4 EMC89873.1 - 0.01 15.6 0.4 0.19 11.4 0.2 2.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF1980 PF09323.5 EMC89873.1 - 0.012 15.3 0.5 0.017 14.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4519 PF15012.1 EMC89873.1 - 0.46 10.4 1.8 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4515 PF14988.1 EMC89874.1 - 7.1e-17 61.7 16.9 7.1e-17 61.7 11.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) Lectin_N PF03954.9 EMC89874.1 - 0.0073 15.7 0.2 0.0073 15.7 0.1 2.2 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain IncA PF04156.9 EMC89874.1 - 0.0083 15.7 15.5 0.0083 15.7 10.8 2.0 1 1 1 2 2 2 2 IncA protein zf-NPL4 PF05020.10 EMC89874.1 - 0.03 13.9 0.6 0.068 12.8 0.2 1.8 1 1 1 2 2 2 0 NPL4 family, putative zinc binding region DUF4618 PF15397.1 EMC89874.1 - 0.25 10.6 26.3 0.84 8.9 14.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 EMC89874.1 - 1.4 8.7 5.1 6.5 6.5 1.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.16 EMC89874.1 - 7.1 6.9 16.8 5.2 7.4 4.7 3.1 2 1 1 3 3 3 0 Spectrin repeat AAA PF00004.24 EMC89875.1 - 1.5e-31 109.3 0.5 3.2e-31 108.2 0.1 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMC89875.1 - 0.0016 18.2 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EMC89875.1 - 0.091 12.8 0.1 7.6 6.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain Peptidase_M28 PF04389.12 EMC89876.1 - 6e-43 146.6 0.0 8.2e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.20 EMC89877.1 - 8.3e-64 215.2 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89877.1 - 2.8e-33 115.0 0.0 4.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EMC89877.1 - 1.4e-26 91.9 18.9 2.7e-13 49.3 2.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 EMC89877.1 - 5e-10 39.5 0.2 1.6e-08 34.7 0.0 2.5 1 1 0 2 2 2 1 PH domain Kinase-like PF14531.1 EMC89877.1 - 4.3e-07 29.1 0.0 2.4e-05 23.4 0.0 2.7 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.9 EMC89877.1 - 4.5e-05 22.6 0.0 8.6e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC89877.1 - 0.027 14.1 0.0 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMC89877.1 - 0.045 12.5 0.1 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EMC89877.1 - 0.11 11.8 0.2 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family zf-RING-like PF08746.6 EMC89877.1 - 0.11 12.4 16.2 1.4 9.0 3.3 2.8 2 0 0 2 2 2 0 RING-like domain PHD PF00628.24 EMC89877.1 - 0.15 11.7 16.6 1.5 8.5 3.6 2.6 2 0 0 2 2 2 0 PHD-finger C1_3 PF07649.7 EMC89877.1 - 0.15 12.0 13.3 0.86 9.6 0.9 2.7 2 0 0 2 2 2 0 C1-like domain FYVE_2 PF02318.11 EMC89877.1 - 0.31 10.9 10.0 1.8 8.4 3.3 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 EMC89877.1 - 1.8 8.3 16.3 0.25 11.0 1.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EMC89877.1 - 2.6 7.4 10.4 1.1 8.5 0.4 2.8 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 EMC89877.1 - 6.8 6.5 13.6 0.34 10.7 0.6 3.0 2 0 0 2 2 2 0 Double zinc ribbon Methyltransf_28 PF02636.12 EMC89878.1 - 2.4e-73 246.6 0.0 3.2e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CBF PF03914.12 EMC89879.1 - 1.2e-49 167.9 1.3 6.8e-49 165.4 0.2 2.7 2 0 0 2 2 2 1 CBF/Mak21 family Sulfotransfer_1 PF00685.22 EMC89881.1 - 2e-60 204.3 0.0 2.6e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EMC89881.1 - 0.00073 20.4 0.0 0.001 19.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 EMC89881.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Stf0 sulphotransferase VWC PF00093.13 EMC89882.1 - 7.8e-41 137.9 249.0 4.7e-11 42.6 9.9 15.4 9 2 6 15 15 15 7 von Willebrand factor type C domain Antistasin PF02822.9 EMC89882.1 - 7.9e-16 58.0 61.0 4.3e-07 30.1 6.3 16.0 18 2 0 18 18 18 4 Antistasin family TMEM154 PF15102.1 EMC89882.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family FEZ PF07763.8 EMC89883.1 - 4e-95 318.1 15.0 5e-95 317.8 10.4 1.1 1 0 0 1 1 1 1 FEZ-like protein SCHIP-1 PF10148.4 EMC89883.1 - 0.00038 19.9 0.7 0.0006 19.2 0.5 1.3 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 1-cysPrx_C PF10417.4 EMC89883.1 - 0.072 12.7 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin EURL PF06937.6 EMC89883.1 - 0.18 11.2 8.6 0.08 12.3 4.3 1.6 1 1 0 1 1 1 0 EURL protein PmbA_TldD PF01523.11 EMC89883.1 - 0.3 10.2 3.5 0.2 10.8 0.4 1.9 2 0 0 2 2 2 0 Putative modulator of DNA gyrase MRP-L46 PF11788.3 EMC89883.1 - 1 10.0 8.3 0.42 11.2 2.7 2.2 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 Topo-VIb_trans PF09239.6 EMC89883.1 - 1.1 8.7 4.5 0.48 9.9 0.4 2.2 1 1 1 2 2 2 0 Topoisomerase VI B subunit, transducer NPV_P10 PF05531.7 EMC89883.1 - 2.2 8.5 8.5 9.5 6.5 0.6 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Transposase_24 PF03004.9 EMC89883.1 - 3.2 7.6 7.1 26 4.7 1.6 2.8 1 1 2 3 3 3 0 Plant transposase (Ptta/En/Spm family) 7tm_1 PF00001.16 EMC89884.1 - 4.9e-29 101.2 12.4 5.6e-29 101.0 8.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) VWA PF00092.23 EMC89885.1 - 1.6e-78 262.4 4.2 7.3e-43 146.3 0.7 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 EMC89885.1 - 7.6e-28 97.7 0.1 2.8e-13 50.3 0.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.14 EMC89885.1 - 8e-25 86.6 0.1 2.2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 LCCL domain VWA_3 PF13768.1 EMC89885.1 - 1.4e-06 28.0 0.0 0.0075 15.9 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EMC89885.1 - 4.6e-05 23.3 0.2 0.029 14.1 0.0 2.3 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_CoxE PF05762.9 EMC89885.1 - 0.00023 20.3 0.0 0.033 13.3 0.0 2.4 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF1194 PF06707.6 EMC89885.1 - 0.00042 19.3 0.3 0.8 8.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1194) Mucin PF01456.12 EMC89885.1 - 0.0011 18.8 13.1 0.0019 17.9 9.1 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Med3 PF11593.3 EMC89885.1 - 0.021 14.0 4.2 0.026 13.8 2.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rxt3 PF08642.5 EMC89885.1 - 0.098 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 WD40 PF00400.27 EMC89886.1 - 1.9e-44 148.0 13.2 1.7e-09 37.2 0.1 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Striatin PF08232.7 EMC89886.1 - 4.3e-25 88.5 2.0 4.3e-25 88.5 1.4 2.2 2 0 0 2 2 2 1 Striatin family Nup160 PF11715.3 EMC89886.1 - 0.0056 14.8 0.2 1 7.4 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Corona_I PF03187.9 EMC89886.1 - 0.057 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Corona nucleocapsid I protein HEAT_2 PF13646.1 EMC89887.1 - 4.8e-12 45.9 17.7 0.0013 18.9 0.4 8.0 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.17 EMC89887.1 - 3.8e-09 35.8 33.9 0.48 10.6 0.8 11.6 11 0 0 11 11 11 3 HEAT repeat HisKA_3 PF07730.8 EMC89887.1 - 0.11 12.8 2.7 0.75 10.1 0.1 3.5 3 0 0 3 3 3 0 Histidine kinase DUF4187 PF13821.1 EMC89888.1 - 3.9e-19 67.9 4.3 2.2e-18 65.5 3.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EMC89888.1 - 1.5e-15 56.6 1.1 3.3e-15 55.5 0.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMC89888.1 - 6.4e-07 29.1 4.1 6.4e-07 29.1 2.8 2.6 2 1 0 2 2 2 1 DExH-box splicing factor binding site DUF3818 PF12825.2 EMC89888.1 - 0.73 8.4 7.6 0.1 11.2 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) AAA_11 PF13086.1 EMC89888.1 - 1.3 8.5 8.6 2.8 7.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Yae1_N PF09811.4 EMC89889.1 - 5e-10 38.7 40.0 0.003 17.0 11.3 4.2 1 1 1 2 2 2 2 Essential protein Yae1, N terminal p450 PF00067.17 EMC89890.1 - 9.4e-53 179.3 0.2 1.1e-52 179.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_11 PF13414.1 EMC89891.1 - 3.1e-09 36.3 4.7 4.2e-06 26.3 0.6 3.8 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 EMC89891.1 - 2.5e-06 26.8 2.5 0.0039 16.8 0.8 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMC89891.1 - 4.9e-06 25.9 6.1 0.0065 16.0 1.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC89891.1 - 2.1e-05 24.3 1.9 0.88 9.9 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC89891.1 - 8.2e-05 22.8 0.1 0.0041 17.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC89891.1 - 0.0034 17.1 11.1 0.13 12.2 0.6 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMC89891.1 - 0.01 15.7 1.1 0.2 11.5 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Uds1 PF15456.1 EMC89891.1 - 0.059 13.3 3.9 0.2 11.6 2.7 2.0 1 1 0 1 1 1 0 Up-regulated During Septation Sec16_C PF12931.2 EMC89891.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_16 PF13432.1 EMC89891.1 - 0.08 13.6 2.4 1.8 9.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC89891.1 - 1.1 9.4 5.6 0.23 11.6 0.5 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BORG_CEP PF14957.1 EMC89892.1 - 3.8e-40 137.6 1.4 5.5e-40 137.0 1.0 1.3 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.23 EMC89892.1 - 4.2e-08 33.5 0.2 9.7e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain NACHT PF05729.7 EMC89893.1 - 8.4e-26 90.6 0.4 5.9e-25 87.8 0.1 2.4 2 0 0 2 2 2 1 NACHT domain CARD PF00619.16 EMC89893.1 - 2e-17 62.8 1.7 7.2e-17 61.0 0.0 2.9 3 0 0 3 3 3 1 Caspase recruitment domain LRR_4 PF12799.2 EMC89893.1 - 0.0001 21.8 24.3 0.0097 15.5 1.6 7.1 6 2 3 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC89893.1 - 0.00015 21.4 18.2 0.23 11.2 0.8 5.7 3 2 2 5 5 5 4 Leucine rich repeat AAA_19 PF13245.1 EMC89893.1 - 0.0047 16.6 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain LRR_6 PF13516.1 EMC89893.1 - 0.0077 16.1 14.5 0.13 12.3 0.1 6.7 7 0 0 7 7 7 1 Leucine Rich repeat AAA_22 PF13401.1 EMC89893.1 - 0.011 15.8 0.0 0.068 13.3 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMC89893.1 - 0.042 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRR_1 PF00560.28 EMC89893.1 - 0.21 11.7 7.6 17 5.9 0.0 5.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EMC89893.1 - 0.46 10.9 11.0 60 4.5 0.2 6.9 6 0 0 6 6 6 0 Leucine rich repeat DUF3643 PF12356.3 EMC89894.1 - 6.4e-68 227.2 1.8 2.2e-67 225.4 1.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3643) UQ_con PF00179.21 EMC89894.1 - 3.6e-29 100.9 0.0 8.5e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BIR PF00653.16 EMC89894.1 - 2.4e-21 75.9 2.8 8e-21 74.2 1.9 2.0 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UEV PF05743.8 EMC89894.1 - 5.3e-05 22.8 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 UEV domain DUF3138 PF11336.3 EMC89894.1 - 1.2 7.2 7.6 2 6.4 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TPR_11 PF13414.1 EMC89895.1 - 5.3e-22 77.2 7.9 4.9e-11 42.1 0.5 6.9 4 1 3 8 8 8 3 TPR repeat TPR_2 PF07719.12 EMC89895.1 - 1.3e-16 59.1 17.8 0.00072 19.2 0.0 8.8 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC89895.1 - 2e-14 52.7 0.8 0.0037 17.7 0.0 7.7 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMC89895.1 - 3.1e-14 51.8 11.6 0.0024 17.4 0.0 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC89895.1 - 1.6e-10 40.7 14.9 6.8e-05 22.7 0.1 7.0 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC89895.1 - 1e-09 37.4 14.2 0.021 14.5 0.0 8.4 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMC89895.1 - 4.7e-09 35.9 3.0 9.9e-06 25.3 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC89895.1 - 6.8e-09 36.1 0.6 0.00014 22.4 0.1 4.8 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMC89895.1 - 2.1e-07 30.5 7.7 0.00012 22.0 0.0 6.3 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMC89895.1 - 1.2e-06 28.6 5.8 0.0019 18.4 0.2 6.1 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMC89895.1 - 1.4e-05 24.5 7.3 4.7 7.2 0.3 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC89895.1 - 8.5e-05 22.7 2.1 1.6 9.3 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat BTAD PF03704.12 EMC89895.1 - 0.00099 19.4 0.8 0.011 16.0 0.1 2.9 2 2 0 2 2 2 1 Bacterial transcriptional activator domain ChAPs PF09295.5 EMC89895.1 - 0.0044 15.8 0.0 0.96 8.1 0.0 2.5 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 EMC89895.1 - 0.006 16.6 23.2 0.16 12.1 0.9 6.2 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EMC89895.1 - 0.0069 15.7 1.7 0.93 8.8 0.0 3.9 4 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_10 PF13374.1 EMC89895.1 - 0.72 9.8 5.8 19 5.3 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC89895.1 - 2.4 8.0 5.8 7.3 6.5 0.0 4.2 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat EGF_CA PF07645.10 EMC89896.1 - 8e-87 285.0 291.0 8e-10 38.5 3.1 19.4 20 2 1 21 21 21 15 Calcium-binding EGF domain TB PF00683.12 EMC89896.1 - 4.7e-49 163.7 76.3 1.7e-16 59.5 4.8 6.9 7 0 0 7 7 7 4 TB domain cEGF PF12662.2 EMC89896.1 - 6.4e-48 159.9 157.9 2.9e-07 29.9 2.2 17.9 18 1 0 18 18 18 12 Complement Clr-like EGF-like EGF PF00008.22 EMC89896.1 - 2.3e-39 132.8 237.0 0.00014 21.7 2.6 20.0 19 0 0 19 19 19 15 EGF-like domain EGF_3 PF12947.2 EMC89896.1 - 9.2e-19 67.1 190.8 0.00095 19.0 1.1 19.1 18 0 0 18 18 18 14 EGF domain FXa_inhibition PF14670.1 EMC89896.1 - 2.1e-05 24.5 36.2 0.00039 20.4 5.0 19.9 19 2 2 21 21 21 13 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 EMC89896.1 - 0.00033 20.2 12.5 0.00033 20.2 8.7 11.2 7 4 3 10 10 10 3 Plasmodium ookinete surface protein Pvs28 EGF_MSP1_1 PF12946.2 EMC89896.1 - 0.0013 18.4 1.3 0.0013 18.4 0.9 18.2 21 0 0 21 21 21 7 MSP1 EGF domain 1 hEGF PF12661.2 EMC89896.1 - 0.0057 16.6 2.9 0.0057 16.6 2.0 14.8 13 0 0 13 13 13 1 Human growth factor-like EGF RasGEF PF00617.14 EMC89897.1 - 6.8e-47 159.6 0.3 1.1e-46 158.9 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain EF-hand_7 PF13499.1 EMC89897.1 - 1.3e-12 47.6 0.0 8.1e-06 25.8 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair C1_1 PF00130.17 EMC89897.1 - 1.6e-12 46.9 9.3 3.7e-12 45.7 6.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.15 EMC89897.1 - 8.2e-11 41.9 0.1 3.2e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif EF-hand_1 PF00036.27 EMC89897.1 - 1.9e-09 36.1 6.3 0.00015 20.8 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EMC89897.1 - 4.3e-09 35.4 1.6 0.00026 20.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EMC89897.1 - 9.3e-07 27.9 5.9 0.0075 15.5 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EMC89897.1 - 1.6e-05 24.4 1.6 0.091 12.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair Eno-Rase_FAD_bd PF07055.7 EMC89897.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DUF2465 PF10239.4 EMC89898.1 - 3.5e-135 450.2 0.0 4.5e-135 449.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) zf-C2H2_jaz PF12171.3 EMC89899.1 - 0.0004 20.4 1.8 0.0004 20.4 1.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC89899.1 - 0.017 15.2 2.4 2 8.5 0.2 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMC89899.1 - 6.7 7.0 14.8 0.16 12.1 1.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type EGF PF00008.22 EMC89900.1 - 9.3e-31 105.3 75.0 2.2e-08 33.8 5.4 6.4 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 EMC89900.1 - 1.6e-12 46.6 53.5 0.0035 17.3 2.8 7.8 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.8 EMC89900.1 - 3.1e-09 36.8 96.9 0.015 15.4 9.1 6.4 6 0 0 6 6 6 5 EGF-like domain Laminin_EGF PF00053.19 EMC89900.1 - 0.0025 17.6 77.0 0.045 13.6 8.7 6.4 2 2 3 6 6 6 5 Laminin EGF-like (Domains III and V) EGF_3 PF12947.2 EMC89900.1 - 0.017 15.0 67.9 0.12 12.3 3.4 6.3 4 1 1 5 5 5 0 EGF domain EGF_CA PF07645.10 EMC89900.1 - 0.18 11.8 78.3 0.11 12.5 4.8 6.6 3 1 3 6 6 6 0 Calcium-binding EGF domain Pilt PF15453.1 EMC89901.1 - 1.3e-118 396.3 27.7 1.6e-90 304.0 13.3 3.6 2 2 2 4 4 4 2 Protein incorporated later into Tight Junctions Fib_alpha PF08702.5 EMC89901.1 - 0.06 13.4 5.6 0.1 12.6 3.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Lebercilin PF15619.1 EMC89901.1 - 0.15 11.4 18.6 0.71 9.2 12.9 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.14 EMC89901.1 - 0.22 11.0 15.1 0.4 10.1 10.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family IncA PF04156.9 EMC89901.1 - 3.4 7.2 18.6 67 3.0 12.8 2.3 1 1 1 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EMC89901.1 - 4.7 4.9 6.9 6.3 4.5 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 EMC89901.1 - 5.3 7.5 9.9 0.7 10.3 1.1 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CALCOCO1 PF07888.6 EMC89901.1 - 8 4.6 16.2 0.074 11.3 4.9 2.1 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Yip1 PF04893.12 EMC89902.1 - 1.1e-05 24.9 17.5 1.8e-05 24.3 12.1 1.5 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.4 EMC89902.1 - 0.013 15.7 1.3 0.036 14.2 0.9 1.9 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 RNA_pol_A_bac PF01000.21 EMC89903.1 - 3.9e-30 104.2 0.0 6.3e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMC89903.1 - 2.5e-16 58.5 0.0 3.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Xpo1 PF08389.7 EMC89904.1 - 2.8e-33 114.9 2.9 1.1e-32 112.9 1.7 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EMC89904.1 - 0.00083 19.2 0.0 0.0037 17.1 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain GTP_EFTU PF00009.22 EMC89905.1 - 7.5e-28 97.2 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC89905.1 - 1.5e-09 37.9 0.8 4.5e-09 36.3 0.5 1.9 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC89905.1 - 0.00012 22.0 0.1 0.00045 20.2 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EMC89905.1 - 0.00086 18.8 0.1 12 5.3 0.0 3.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EMC89905.1 - 0.0017 18.3 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMC89905.1 - 0.014 15.8 0.0 0.14 12.6 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 EMC89905.1 - 0.042 13.0 0.1 5 6.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMC89905.1 - 0.05 12.8 0.1 3 7.1 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EMC89905.1 - 0.078 12.7 0.2 1.8 8.3 0.1 2.3 1 1 1 2 2 2 0 Dynamin family DUF4461 PF14688.1 EMC89905.1 - 0.099 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) p31comet PF06581.7 EMC89906.1 - 2.9e-66 223.0 0.0 3.5e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding EHN PF06441.7 EMC89907.1 - 7.7e-35 119.2 0.3 1.3e-34 118.4 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMC89907.1 - 7.2e-16 58.7 0.0 7.9e-15 55.3 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC89907.1 - 2.1e-14 53.6 0.1 2.6e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_S18 PF01084.15 EMC89908.1 - 1.2e-15 57.0 0.0 2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 Response_reg PF00072.19 EMC89909.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain VEGF_C PF14554.1 EMC89910.1 - 2.5e-32 110.4 21.2 2.5e-32 110.4 14.7 2.3 2 0 0 2 2 2 1 VEGF heparin-binding domain PDGF PF00341.12 EMC89910.1 - 1.5e-27 95.5 5.7 1.5e-27 95.5 4.0 2.4 2 1 0 2 2 2 1 PDGF/VEGF domain Ribosomal_L14 PF00238.14 EMC89911.1 - 2.1e-24 85.6 0.0 2.6e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF221 PF02714.10 EMC89912.1 - 2.8e-94 315.6 21.1 5.6e-94 314.6 14.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMC89912.1 - 5.6e-20 71.4 0.0 5.6e-20 71.4 0.0 5.7 6 1 1 7 7 7 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMC89912.1 - 1.6e-11 44.5 0.2 3.9e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 EMC89912.1 - 0.045 13.3 0.1 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4006 PF13179.1 EMC89912.1 - 3.6 7.1 5.3 41 3.8 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF4006) HSP90 PF00183.13 EMC89913.1 - 2.5e-22 78.9 0.0 2.9e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Hsp90 protein UAA PF08449.6 EMC89914.1 - 1.3e-89 300.1 21.2 1.6e-89 299.8 14.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMC89914.1 - 4e-07 30.1 21.1 2.7e-05 24.1 8.3 3.0 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EMC89914.1 - 0.019 14.6 21.4 0.17 11.5 14.4 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family Ank PF00023.25 EMC89915.1 - 1.1e-37 125.9 5.8 4.8e-08 32.4 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EMC89915.1 - 4.1e-34 116.7 0.8 1.8e-19 69.8 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMC89915.1 - 8.6e-26 89.3 9.1 1.2e-07 31.7 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC89915.1 - 1.6e-25 86.6 1.2 0.0017 18.3 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EMC89915.1 - 1.7e-24 85.7 0.4 3.6e-10 40.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF3447 PF11929.3 EMC89915.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) LRR_6 PF13516.1 EMC89916.1 - 4.5e-17 60.1 27.1 1.3e-05 24.7 0.1 8.6 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 EMC89916.1 - 3.9e-09 35.9 16.8 5e-05 22.8 0.1 5.5 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC89916.1 - 0.0026 17.4 22.6 0.19 11.5 4.4 4.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EMC89916.1 - 0.003 17.3 14.5 5.6 7.4 0.0 6.6 6 1 0 6 6 6 2 Leucine Rich Repeat tRNA-synt_2c PF01411.14 EMC89917.1 - 3e-162 540.7 0.0 4.4e-162 540.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EMC89917.1 - 8.8e-09 35.1 0.5 7e-08 32.2 0.1 2.5 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain FHA PF00498.21 EMC89918.1 - 3.1e-16 59.2 0.0 4.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain FtsJ PF01728.14 EMC89919.1 - 8.8e-38 130.0 0.0 1.9e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.18 EMC89919.1 - 1.2e-12 47.4 2.5 1.2e-12 47.4 1.7 2.2 2 0 0 2 2 2 1 G-patch domain WW PF00397.21 EMC89919.1 - 0.0015 18.3 0.5 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 WW domain mRNA_cap_enzyme PF01331.14 EMC89919.1 - 0.0023 17.6 0.0 0.0071 16.0 0.0 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 EMC89919.1 - 0.019 14.3 0.5 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 ATP dependent DNA ligase domain G-patch_2 PF12656.2 EMC89919.1 - 0.06 13.2 1.5 0.17 11.7 1.0 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site CCDC-167 PF15188.1 EMC89920.1 - 1e-15 57.3 1.2 1.1e-15 57.3 0.9 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 I-set PF07679.11 EMC89921.1 - 2e-62 207.0 0.1 8e-12 44.8 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC89921.1 - 1.8e-55 184.9 7.6 7.4e-09 35.6 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain MAM PF00629.18 EMC89921.1 - 4.3e-50 169.5 0.0 1.3e-49 167.9 0.0 1.9 2 0 0 2 2 2 1 MAM domain ig PF00047.20 EMC89921.1 - 4.5e-37 125.9 7.6 6.5e-07 29.3 0.0 7.6 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 EMC89921.1 - 2.5e-35 120.7 18.7 1.7e-07 31.6 0.0 7.2 7 1 0 7 7 7 6 Immunoglobulin domain V-set PF07686.12 EMC89921.1 - 4.7e-30 103.8 13.2 2.1e-06 27.5 0.0 9.8 6 4 1 7 7 7 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC89921.1 - 5.6e-11 42.2 6.2 0.027 14.3 0.0 6.1 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 EMC89921.1 - 1.3e-05 25.0 2.2 0.16 12.0 0.0 4.7 4 1 0 4 4 4 1 Immunoglobulin C1-set domain BiPBP_C PF06832.7 EMC89921.1 - 0.021 14.7 0.0 2.4 8.1 0.0 3.5 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family zf-AN1 PF01428.11 EMC89922.1 - 3.6e-11 42.7 7.0 9e-11 41.4 4.9 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 EMC89922.1 - 0.14 12.0 8.8 0.058 13.2 3.5 2.1 2 0 0 2 2 2 0 IBR domain zf-RING_4 PF14570.1 EMC89922.1 - 0.61 9.7 5.1 1.5 8.4 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BTB PF00651.26 EMC89923.1 - 8.9e-28 96.4 0.3 3.5e-26 91.3 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EMC89923.1 - 4.5e-23 81.0 0.4 1e-21 76.7 0.2 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.20 EMC89923.1 - 1.2e-16 60.7 0.1 6.4e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 F5/8 type C domain Tissue_fac PF01108.12 EMC89923.1 - 2 8.2 6.4 2.2 8.0 1.5 2.4 2 0 0 2 2 2 0 Tissue factor Glyoxalase PF00903.20 EMC89924.1 - 6e-26 90.9 0.0 7.6e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMC89924.1 - 1.1e-17 64.5 0.0 2e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMC89924.1 - 7.2e-11 42.0 0.0 5.5e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMC89924.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.8 2 1 0 2 2 2 0 Glyoxalase-like domain DHC_N1 PF08385.7 EMC89925.1 - 1.6e-128 429.6 9.3 1.6e-128 429.6 6.5 3.0 3 2 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 EMC89926.1 - 6.3e-157 523.6 0.2 6.3e-157 523.6 0.2 3.0 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 EMC89926.1 - 5.3e-72 242.0 0.0 1.4e-71 240.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EMC89926.1 - 6.6e-59 198.5 1.8 6.6e-59 198.5 1.3 3.5 4 0 0 4 4 4 1 ATP-binding dynein motor region D5 MT PF12777.2 EMC89926.1 - 4.7e-45 153.8 10.4 8.2e-45 153.0 7.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EMC89926.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 7tm_2 PF00002.19 EMC89927.1 - 6.9e-79 264.3 24.4 9e-79 263.9 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 EMC89927.1 - 7.9e-17 61.0 3.3 2.1e-16 59.6 2.3 1.8 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 EMC89927.1 - 3.1e-06 26.2 17.5 5.4e-06 25.5 12.1 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ion_trans_2 PF07885.11 EMC89928.1 - 1.7e-30 104.5 19.4 4.1e-18 64.8 1.6 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 EMC89928.1 - 0.059 12.6 9.7 0.28 10.4 0.4 2.4 2 0 0 2 2 2 0 Ion transport protein UPF0542 PF15086.1 EMC89928.1 - 0.068 12.9 0.5 0.15 11.7 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Ion_trans_2 PF07885.11 EMC89929.1 - 1.2e-29 101.8 12.0 4e-16 58.4 1.1 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans_2 PF07885.11 EMC89930.1 - 2.2e-34 117.0 15.7 6.5e-19 67.4 0.1 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 EMC89930.1 - 0.00075 18.8 11.9 0.0016 17.7 1.1 2.3 2 0 0 2 2 2 2 Ion transport protein AP-5_subunit_s1 PF15001.1 EMC89930.1 - 0.12 12.2 0.5 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 FUSC_2 PF13515.1 EMC89930.1 - 2.8 7.8 9.5 0.32 10.9 2.4 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein-like Kinesin PF00225.18 EMC89931.1 - 7.3e-73 245.1 0.6 7.3e-73 245.1 0.4 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF1019 PF06254.6 EMC89931.1 - 0.31 11.2 3.2 2.7 8.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1019) FH2 PF02181.18 EMC89932.1 - 1.8e-109 366.0 13.2 1.8e-109 366.0 9.2 2.8 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.11 EMC89932.1 - 2.3e-61 206.6 4.1 2.3e-61 206.6 2.9 4.6 4 2 1 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EMC89932.1 - 4.3e-54 182.7 0.1 4.3e-54 182.7 0.1 3.7 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Bacillus_HBL PF05791.6 EMC89932.1 - 0.088 12.1 9.8 0.082 12.2 3.2 2.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2203 PF09969.4 EMC89932.1 - 4.2 7.6 18.5 0.81 9.9 0.6 4.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) SMN PF06003.7 EMC89932.1 - 9.6 5.2 23.4 0.72 8.9 11.6 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) MoaC PF01967.16 EMC89933.1 - 8.1e-53 177.7 0.7 1.4e-52 176.9 0.5 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EMC89933.1 - 6.8e-39 132.4 0.0 1.1e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EMC89933.1 - 7.2e-30 104.3 0.1 1.9e-29 102.9 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EMC89933.1 - 1.6e-09 38.0 0.0 3.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMC89933.1 - 3.4e-08 33.5 0.0 1.2e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain LRR_8 PF13855.1 EMC89935.1 - 2.2e-28 97.7 17.5 1.2e-12 47.4 2.1 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMC89935.1 - 2.6e-19 68.3 19.7 1.6e-06 27.5 2.8 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.11 EMC89935.1 - 5.1e-15 55.0 0.0 1.1e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 EMC89935.1 - 2.5e-12 45.0 21.6 0.043 13.8 0.5 8.0 8 0 0 8 8 7 4 Leucine Rich Repeat LRR_5 PF13306.1 EMC89935.1 - 3.9e-12 45.9 0.1 1.7e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) Ig_3 PF13927.1 EMC89935.1 - 1.1e-07 32.2 0.3 8.5e-07 29.3 0.0 2.7 2 1 1 3 3 3 1 Immunoglobulin domain fn3 PF00041.16 EMC89935.1 - 2.1e-07 30.9 0.9 6.3e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 Fibronectin type III domain Ig_2 PF13895.1 EMC89935.1 - 4e-06 26.8 0.1 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 1 1 Immunoglobulin domain ig PF00047.20 EMC89935.1 - 2.9e-05 24.0 0.0 7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 EMC89935.1 - 6.5e-05 22.5 3.8 0.003 17.1 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat V-set PF07686.12 EMC89935.1 - 0.0061 16.4 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_7 PF13504.1 EMC89935.1 - 0.03 14.4 21.0 2.2 8.8 0.1 7.1 8 0 0 8 8 6 0 Leucine rich repeat Bromo_TP PF07524.8 EMC89937.1 - 7.4e-22 76.8 0.2 1.8e-21 75.6 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated PfkB PF00294.19 EMC89941.1 - 2.6e-56 190.9 0.1 3.2e-56 190.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMC89941.1 - 9.4e-07 28.2 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CoA_binding_2 PF13380.1 EMC89941.1 - 0.0077 16.3 0.1 0.099 12.8 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Aldolase PF01081.14 EMC89941.1 - 0.032 13.3 1.2 3.5 6.7 0.1 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase Mur_ligase PF01225.20 EMC89941.1 - 0.073 13.1 0.1 0.26 11.3 0.1 2.0 1 1 0 1 1 1 0 Mur ligase family, catalytic domain BRE PF06113.7 EMC89942.1 - 7.7e-228 754.9 0.1 8.8e-228 754.7 0.1 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.21 EMC89942.1 - 0.002 17.5 2.8 0.73 9.2 0.1 2.7 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme bZIP_1 PF00170.16 EMC89943.1 - 2e-09 37.2 20.0 3.1e-09 36.6 13.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC89943.1 - 1.2e-06 28.1 19.1 2.1e-06 27.4 13.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC89943.1 - 2.4e-05 24.5 14.1 4.1e-05 23.7 9.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HAUS6_N PF14661.1 EMC89943.1 - 0.018 14.4 1.9 0.023 14.0 1.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 EMC89943.1 - 0.19 9.5 1.7 0.23 9.2 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMC89943.1 - 0.82 9.2 6.5 1.3 8.5 4.5 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EMC89943.1 - 1 8.3 7.6 1.5 7.8 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EMC89943.1 - 1.1 7.6 4.3 1.5 7.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2681 PF10883.3 EMC89943.1 - 1.3 9.2 6.3 2.6 8.3 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Pox_G5 PF04599.7 EMC89943.1 - 4.9 5.7 6.4 6.9 5.2 4.4 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Lipase_GDSL PF00657.17 EMC89944.1 - 1.2e-91 306.7 0.0 7.4e-30 104.5 0.0 3.9 4 0 0 4 4 4 3 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMC89944.1 - 4.9e-30 104.9 0.1 4.9e-09 36.5 0.1 4.8 3 2 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase family IL7 PF01415.11 EMC89944.1 - 0.063 12.9 0.5 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Interleukin 7/9 family RecR PF02132.10 EMC89944.1 - 0.28 10.6 2.3 4.4 6.8 0.0 3.5 3 0 0 3 3 3 0 RecR protein Metallophos PF00149.23 EMC89945.1 - 1.5e-42 145.3 0.2 1.7e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 EMC89946.1 - 1.1e-43 143.1 10.0 2.9e-10 38.6 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC89946.1 - 6.9e-39 131.8 3.7 1.1e-21 76.7 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC89946.1 - 4.6e-36 122.2 10.0 3.7e-17 61.6 0.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMC89946.1 - 9e-32 106.0 5.4 9.7e-10 37.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMC89946.1 - 2e-28 96.4 5.4 5.6e-07 28.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMC89946.1 - 6.6e-15 54.7 0.1 1.8e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMC89946.1 - 1.3e-09 37.7 0.5 3.5e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMC89946.1 - 1.5e-08 34.6 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EMC89946.1 - 1e-06 28.2 0.0 0.17 11.5 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EMC89946.1 - 1.3e-06 28.2 0.5 6.5e-06 26.0 0.1 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 EMC89946.1 - 0.00061 19.2 1.6 0.00072 19.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 EMC89946.1 - 0.001 18.8 0.5 0.17 11.6 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 EMC89946.1 - 0.0043 16.6 0.1 0.12 11.9 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 EMC89946.1 - 0.013 15.4 1.7 1.8 8.6 0.1 2.4 3 0 0 3 3 2 0 RNA polymerase Rpb4 Poly_export PF02563.11 EMC89946.1 - 0.04 13.6 0.1 2.6 7.8 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein DUF3349 PF11829.3 EMC89946.1 - 0.059 13.8 0.4 11 6.4 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) MotA_activ PF09114.5 EMC89946.1 - 0.059 13.1 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 EMC89946.1 - 0.064 12.8 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 EMC89946.1 - 0.083 12.4 0.1 0.51 9.8 0.0 1.9 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF1880 PF08976.6 EMC89946.1 - 0.1 12.7 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) CMD PF02627.15 EMC89946.1 - 0.13 12.1 0.2 4 7.3 0.0 2.5 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 EMC89946.1 - 6.4 7.2 7.5 81 3.6 0.8 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-C3HC4 PF00097.20 EMC89948.1 - 2.7e-08 33.3 13.9 2.7e-08 33.3 9.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC89948.1 - 6e-08 32.5 13.6 6e-08 32.5 9.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC89948.1 - 2.2e-07 30.6 11.7 5.2e-07 29.3 8.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC89948.1 - 1.4e-05 24.6 11.5 1.4e-05 24.6 7.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC89948.1 - 0.00029 20.4 15.3 0.0014 18.3 10.1 2.3 1 1 2 3 3 3 1 zinc-RING finger domain zf-Nse PF11789.3 EMC89948.1 - 0.00043 19.7 8.7 0.00077 18.9 6.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EMC89948.1 - 0.00069 19.3 3.8 0.00069 19.3 2.6 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EMC89948.1 - 0.0014 18.6 8.9 0.0014 18.6 6.2 1.8 2 1 0 2 2 2 1 RING-H2 zinc finger Rad60-SLD PF11976.3 EMC89948.1 - 0.0045 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-Apc11 PF12861.2 EMC89948.1 - 0.023 14.4 4.5 0.049 13.4 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EMC89948.1 - 0.03 14.1 0.4 0.03 14.1 0.3 1.8 2 0 0 2 2 1 0 Double zinc ribbon ubiquitin PF00240.18 EMC89948.1 - 0.079 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family zf-C3HC4_4 PF15227.1 EMC89948.1 - 0.084 12.7 13.9 0.22 11.4 9.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC89948.1 - 0.59 9.9 9.3 0.15 11.8 4.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EMC89948.1 - 4.1 7.0 11.2 14 5.3 7.4 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EMC89948.1 - 4.6 7.1 9.5 12 5.8 6.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) CUE PF02845.11 EMC89951.1 - 1.6e-10 40.2 0.0 2.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain Trypsin_2 PF13365.1 EMC89952.1 - 3.3e-10 39.9 0.0 3.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EMC89952.1 - 0.0018 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.4 EMC89952.1 - 0.085 11.2 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 IRS PF02174.12 EMC89953.1 - 2.1e-31 107.4 1.4 1.7e-15 56.4 0.1 2.4 2 0 0 2 2 2 2 PTB domain (IRS-1 type) Pkinase PF00069.20 EMC89955.1 - 9.8e-70 234.6 0.0 1.1e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89955.1 - 5e-41 140.4 0.0 6e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC89955.1 - 3.1e-05 23.0 0.0 0.0003 19.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF1998 PF09369.5 EMC89955.1 - 0.094 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1998) FH2 PF02181.18 EMC89956.1 - 2.3e-87 293.2 8.1 2.3e-87 293.2 5.6 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Melibiase PF02065.13 EMC89957.1 - 1.6e-15 56.7 0.0 4.5e-14 51.9 0.0 2.1 1 1 1 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 EMC89957.1 - 9e-05 21.7 0.0 0.00072 18.7 0.0 2.0 2 0 0 2 2 2 1 Glycoside hydrolase 97 PH PF00169.24 EMC89958.1 - 1.3e-14 54.2 0.0 1.7e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EMC89958.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EMC89958.1 - 0.00011 22.4 0.1 0.0087 16.2 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 EMC89958.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain AAA_32 PF13654.1 EMC89958.1 - 0.076 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DDDD PF10161.4 EMC89959.1 - 1.9e-31 107.4 0.4 2.1e-31 107.3 0.2 1.0 1 0 0 1 1 1 1 Putative mitochondrial precursor protein Complex1_LYR PF05347.10 EMC89960.1 - 7.9e-12 44.7 0.1 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMC89960.1 - 4.4e-08 33.2 0.0 9.5e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMC89960.1 - 0.0015 18.9 0.1 0.0018 18.7 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like WWbp PF10349.4 EMC89962.1 - 7e-21 75.2 27.5 7e-21 75.2 19.1 2.2 1 1 1 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 EMC89962.1 - 5.6e-10 38.5 0.1 8.4e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 EMC89962.1 - 0.078 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Septin PF00735.13 EMC89963.1 - 9.8e-116 385.6 1.6 1.1e-115 385.4 1.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMC89963.1 - 2.2e-08 34.0 0.2 4e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC89963.1 - 8.2e-07 28.3 0.5 1.9e-06 27.1 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMC89963.1 - 3e-05 23.2 0.1 5.5e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EMC89963.1 - 5.1e-05 22.7 0.4 0.0051 16.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMC89963.1 - 0.00019 21.3 8.0 0.027 14.2 0.5 3.3 2 2 2 4 4 4 2 Dynamin family FtsK_SpoIIIE PF01580.13 EMC89963.1 - 0.00024 20.6 0.3 0.0016 17.9 0.1 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EMC89963.1 - 0.00031 20.2 0.3 0.00033 20.2 0.2 1.5 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 EMC89963.1 - 0.00062 20.2 0.9 0.0023 18.3 0.6 2.1 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EMC89963.1 - 0.00092 19.5 0.2 0.0034 17.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Ras PF00071.17 EMC89963.1 - 0.0035 16.7 0.2 0.01 15.1 0.1 1.9 1 1 0 2 2 2 1 Ras family AAA_16 PF13191.1 EMC89963.1 - 0.0036 17.3 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMC89963.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EMC89963.1 - 0.0067 15.9 0.1 0.53 9.7 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EMC89963.1 - 0.015 14.8 0.1 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 EMC89963.1 - 0.02 13.5 0.0 0.043 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMC89963.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EMC89963.1 - 0.035 12.9 1.1 0.042 12.6 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain IIGP PF05049.8 EMC89963.1 - 0.039 12.7 0.9 0.072 11.8 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 EMC89963.1 - 0.042 13.1 0.1 0.088 12.0 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.9 EMC89963.1 - 0.043 12.8 0.1 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.9 EMC89963.1 - 0.052 13.2 0.4 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EMC89963.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMC89963.1 - 0.085 12.7 0.1 0.36 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMC89963.1 - 0.096 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 EMC89963.1 - 0.098 11.5 0.1 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EMC89963.1 - 0.11 12.2 1.1 0.22 11.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 BaffR-Tall_bind PF09256.5 EMC89964.1 - 0.021 14.3 1.5 0.051 13.1 1.1 1.6 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Shisa PF13908.1 EMC89965.1 - 3.5e-36 125.0 1.3 3.8e-36 124.9 0.9 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.6 EMC89965.1 - 0.03 14.2 0.3 0.055 13.4 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF2970 PF11174.3 EMC89965.1 - 0.088 12.4 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) ERK-JNK_inhib PF15002.1 EMC89966.1 - 9.1e-49 165.6 0.0 1e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor DUF2111 PF09884.4 EMC89967.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) Ribosomal_L7Ae PF01248.21 EMC89968.1 - 9.2e-26 89.1 0.1 1.1e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMC89968.1 - 0.00025 20.8 0.1 0.00029 20.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EMC89968.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Ku_N PF03731.10 EMC89970.1 - 3.5e-69 232.6 0.1 8.2e-69 231.4 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EMC89970.1 - 7.9e-60 201.6 0.1 1.9e-59 200.4 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EMC89970.1 - 5e-28 97.4 0.4 2e-27 95.5 0.3 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EMC89970.1 - 6.6e-10 38.2 0.1 1.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain VWA PF00092.23 EMC89970.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain EntA_Immun PF08951.5 EMC89970.1 - 0.59 10.3 3.3 0.56 10.3 0.3 2.4 3 0 0 3 3 3 0 Enterocin A Immunity Peptidase_C97 PF05903.9 EMC89971.1 - 1.3e-43 148.3 0.0 1.5e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PMM PF03332.8 EMC89972.1 - 6.8e-97 323.3 0.1 8e-97 323.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase CSD PF00313.17 EMC89973.1 - 2.5e-13 49.5 0.1 3.4e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EMC89973.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain RNA_pol_Rbc25 PF08292.7 EMC89974.1 - 2.2e-45 153.7 0.1 3.5e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EMC89974.1 - 3.2e-20 72.0 0.1 6.3e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aconitase PF00330.15 EMC89975.1 - 3.8e-184 612.5 0.0 7.3e-184 611.5 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMC89975.1 - 4.1e-47 159.5 0.0 1e-46 158.3 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain PHF5 PF03660.9 EMC89976.1 - 8.3e-39 131.9 14.0 9.2e-39 131.8 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 EMC89976.1 - 0.036 11.7 3.8 0.039 11.6 2.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 bZIP_2 PF07716.10 EMC89977.1 - 7.5e-16 57.6 11.6 7.5e-16 57.6 8.0 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EMC89977.1 - 3.9e-06 26.7 8.5 7.2e-06 25.8 5.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Microtub_assoc PF07989.6 EMC89977.1 - 0.03 14.1 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Microtubule associated bZIP_Maf PF03131.12 EMC89977.1 - 0.031 14.5 5.4 0.074 13.3 3.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.6 EMC89977.1 - 0.041 13.7 0.2 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 EMC89977.1 - 0.053 13.2 0.1 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper RanGAP1_C PF07834.6 EMC89978.1 - 9.4e-81 269.6 0.5 1.5e-80 268.9 0.4 1.3 1 0 0 1 1 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.1 EMC89978.1 - 7.3e-21 71.8 2.5 0.17 12.0 0.2 9.1 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.28 EMC89978.1 - 6.7e-08 31.5 0.1 7.7 6.9 0.1 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.2 EMC89978.1 - 9.9e-06 25.0 0.1 1.6 8.4 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC89978.1 - 3.2e-05 23.5 2.5 0.026 14.2 0.1 4.7 4 1 1 5 5 5 1 Leucine rich repeat LRR_7 PF13504.1 EMC89978.1 - 0.00015 21.4 4.7 11 6.7 0.0 5.8 6 0 0 6 6 5 0 Leucine rich repeat Nop14 PF04147.7 EMC89978.1 - 0.0081 14.1 6.0 0.012 13.5 4.2 1.3 1 0 0 1 1 1 1 Nop14-like family MCR_beta_N PF02783.10 EMC89978.1 - 0.043 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain CRS1_YhbY PF01985.16 EMC89978.1 - 0.2 11.6 1.4 4.1 7.4 0.0 3.0 3 0 0 3 3 3 0 CRS1 / YhbY (CRM) domain Nse4-Nse3_bdg PF15412.1 EMC89978.1 - 0.35 10.7 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE CobT PF06213.7 EMC89978.1 - 0.65 9.0 10.9 1.1 8.2 7.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 EMC89978.1 - 0.91 9.0 11.8 2 7.9 8.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 EMC89978.1 - 2 7.6 8.4 3.3 6.8 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 EMC89978.1 - 2 7.3 5.9 3.3 6.6 4.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.13 EMC89978.1 - 2.5 7.1 10.6 2.2 7.3 5.3 2.0 2 0 0 2 2 2 0 Myc amino-terminal region CDC45 PF02724.9 EMC89978.1 - 2.7 5.9 7.1 0.29 9.1 2.0 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF2457 PF10446.4 EMC89978.1 - 4.6 5.8 13.1 6.3 5.4 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LRR_8 PF13855.1 EMC89979.1 - 1.5e-23 82.2 0.4 1.1e-12 47.4 0.0 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMC89979.1 - 4.1e-13 47.4 0.1 0.05 13.6 0.0 4.1 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_4 PF12799.2 EMC89979.1 - 2.1e-11 43.1 0.5 1.9e-05 24.1 0.2 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMC89979.1 - 9.1e-08 31.1 0.6 2.5 8.6 0.0 4.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EMC89979.1 - 1.8e-05 24.2 0.9 1.2 9.3 0.0 4.1 2 1 2 4 4 4 2 Leucine Rich repeat LRR_5 PF13306.1 EMC89979.1 - 0.00025 20.7 0.0 0.00028 20.5 0.0 1.1 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EMC89979.1 - 0.012 15.1 0.0 0.013 15.0 0.0 1.0 1 0 0 1 1 1 0 Leucine-rich repeat LRR_3 PF07725.7 EMC89979.1 - 0.15 11.8 2.5 0.58 10.0 0.0 2.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 EMC89980.1 - 2.1e-63 209.9 1.4 1.7e-13 50.0 0.0 7.1 4 3 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 EMC89980.1 - 1.5e-39 132.9 8.7 7.7e-07 28.5 0.0 9.3 5 3 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC89980.1 - 1.7e-29 97.3 4.6 0.44 10.7 0.0 15.3 17 0 0 17 17 17 7 Leucine Rich Repeat LRR_6 PF13516.1 EMC89980.1 - 4.5e-15 53.9 3.5 1.2 9.4 0.0 11.5 13 0 0 13 13 13 4 Leucine Rich repeat LRR_7 PF13504.1 EMC89980.1 - 1.2e-09 36.7 23.0 0.68 10.3 0.1 12.9 15 0 0 15 15 15 2 Leucine rich repeat LRR_9 PF14580.1 EMC89980.1 - 2.2e-07 30.5 0.2 0.21 11.1 0.0 4.4 3 1 2 5 5 5 2 Leucine-rich repeat MBT PF02820.13 EMC89981.1 - 3.6e-93 305.5 5.3 4e-30 103.5 0.2 4.3 4 0 0 4 4 4 4 mbt repeat KAT11 PF08214.6 EMC89982.1 - 6.5e-80 268.8 0.2 1.2e-79 267.9 0.2 1.4 1 0 0 1 1 1 1 Histone acetylation protein KIX PF02172.11 EMC89982.1 - 1.2e-41 140.5 1.0 2.7e-41 139.4 0.7 1.6 1 0 0 1 1 1 1 KIX domain Creb_binding PF09030.5 EMC89982.1 - 1.8e-33 114.8 21.6 1.8e-33 114.8 15.0 12.7 6 5 7 14 14 14 1 Creb binding DUF902 PF06001.8 EMC89982.1 - 2e-24 85.4 6.8 2e-24 85.4 4.7 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.20 EMC89982.1 - 9.6e-19 67.0 0.0 2.2e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.11 EMC89982.1 - 1.9e-18 66.1 54.1 6.6e-16 58.0 17.8 3.6 3 0 0 3 3 3 2 TAZ zinc finger ZZ PF00569.12 EMC89982.1 - 6.7e-14 51.1 14.2 6.7e-14 51.1 9.8 3.6 4 0 0 4 4 4 1 Zinc finger, ZZ type Npa1 PF11707.3 EMC89982.1 - 0.0019 17.2 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal DREV PF05219.7 EMC89983.1 - 9.3e-136 450.8 0.0 1e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 EMC89983.1 - 7.3e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC89983.1 - 1e-08 35.5 0.0 1.6e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC89983.1 - 3.3e-06 27.4 0.0 5.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC89983.1 - 8.4e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC89983.1 - 6.5e-05 23.4 0.0 0.00031 21.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMC89983.1 - 0.004 16.2 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EMC89983.1 - 0.041 13.2 0.0 0.98 8.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_PK PF05891.7 EMC89983.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase V-set PF07686.12 EMC89984.1 - 1e-07 31.8 0.1 1.5e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC89984.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.20 EMC89984.1 - 0.043 13.9 0.8 0.08 13.0 0.1 2.0 1 1 0 1 1 1 0 Immunoglobulin domain GTPase_Cys_C PF12631.2 EMC89985.1 - 0.011 16.1 0.9 3.7 8.0 0.0 3.6 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Ras PF00071.17 EMC89986.1 - 9.7e-51 171.3 0.0 1.1e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC89986.1 - 3.4e-13 50.1 0.0 4.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC89986.1 - 1.9e-05 23.9 0.0 2.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC89986.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Sec7 PF01369.15 EMC89987.1 - 4.2e-68 228.7 0.1 6e-68 228.2 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EMC89987.1 - 2e-24 85.7 0.0 3.6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMC89987.1 - 2e-06 28.0 2.5 4.7e-06 26.8 0.5 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EMC89987.1 - 0.014 15.3 0.0 0.058 13.2 0.0 2.1 1 1 0 1 1 1 0 PH domain PH_8 PF15409.1 EMC89987.1 - 0.035 14.1 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.20 EMC89988.1 - 1.8e-44 151.8 4.4 1.4e-30 106.2 0.1 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMC89988.1 - 2.2e-25 89.2 1.1 1.3e-18 67.0 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SlyX PF04102.7 EMC89988.1 - 0.0052 17.1 1.4 0.017 15.4 1.0 1.8 1 0 0 1 1 1 1 SlyX DUF641 PF04859.7 EMC89988.1 - 0.0092 15.7 0.7 0.019 14.7 0.5 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) P4Ha_N PF08336.6 EMC89988.1 - 0.012 15.4 1.0 0.031 14.0 0.7 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FliJ PF02050.11 EMC89988.1 - 0.04 13.9 4.2 0.084 12.9 2.9 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein TMF_TATA_bd PF12325.3 EMC89988.1 - 0.068 12.9 5.5 0.075 12.7 2.4 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EMC89988.1 - 0.076 12.8 2.6 0.24 11.2 1.8 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APH PF01636.18 EMC89988.1 - 0.27 10.9 1.5 0.6 9.7 0.1 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family DivIC PF04977.10 EMC89988.1 - 0.41 10.1 3.6 0.34 10.4 1.1 1.9 2 0 0 2 2 2 0 Septum formation initiator Nnf1 PF03980.9 EMC89988.1 - 0.49 10.4 6.8 0.38 10.7 1.3 3.1 3 1 0 3 3 3 0 Nnf1 GST_C_3 PF14497.1 EMC89989.1 - 5.5e-06 26.7 0.3 1.2e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMC89989.1 - 4.6e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC89989.1 - 0.00025 20.8 0.0 0.00063 19.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MutL_C PF08676.6 EMC89990.1 - 1.2e-28 99.4 0.0 3.1e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EMC89990.1 - 3.6e-23 81.2 0.0 3.6e-23 81.2 0.0 2.6 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMC89990.1 - 2e-13 50.1 0.0 4.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMC89990.1 - 7.6e-11 41.7 0.1 2.3e-10 40.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MORN PF02493.15 EMC89991.1 - 9.7e-39 128.8 81.5 9e-08 31.4 0.2 10.9 11 0 0 11 11 11 10 MORN repeat DUF1712 PF08217.6 EMC89992.1 - 2.3e-95 320.1 7.0 3e-85 286.7 0.4 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) Methyltransf_20 PF12147.3 EMC89992.1 - 0.0098 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase EF-hand_1 PF00036.27 EMC89993.1 - 2.6e-13 48.1 2.4 1.7e-06 26.8 0.6 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC89993.1 - 5e-13 48.9 0.7 8.2e-13 48.2 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC89993.1 - 2.8e-12 45.4 1.0 2.2e-06 27.0 0.2 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EMC89993.1 - 5.8e-11 41.2 3.8 2.6e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMC89993.1 - 4.8e-09 35.6 0.9 0.00022 20.7 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC89993.1 - 0.014 15.4 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EMC89993.1 - 0.039 13.6 2.5 0.19 11.4 0.4 2.5 2 1 1 3 3 3 0 EF hand Toprim_2 PF13155.1 EMC89993.1 - 0.09 13.1 0.1 12 6.2 0.0 2.1 1 1 1 2 2 2 0 Toprim-like EF-hand_1 PF00036.27 EMC89994.1 - 5.1e-13 47.2 1.7 1.8e-05 23.6 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EMC89994.1 - 5.2e-11 41.4 1.7 2.8e-05 23.6 0.1 2.8 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EMC89994.1 - 2.8e-10 39.0 2.4 6.6e-05 22.0 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMC89994.1 - 3e-10 39.5 0.6 1.8e-08 33.8 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 EMC89994.1 - 3e-10 40.0 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC89994.1 - 0.002 18.1 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region HLH PF00010.21 EMC89995.1 - 5.7e-17 61.1 3.7 1.2e-16 60.0 2.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RepB PF07506.6 EMC89995.1 - 0.02 14.7 2.4 0.028 14.2 1.7 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein Hyd_WA PF06462.7 EMC89996.1 - 5.5e-88 288.2 62.1 1.4e-14 53.4 1.9 11.9 12 0 0 12 12 12 10 Propeller Pex24p PF06398.6 EMC89996.1 - 7.3e-22 77.6 23.1 1.3e-12 47.1 2.5 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF2367 PF10164.4 EMC89997.1 - 3e-31 107.1 5.1 3.3e-31 107.0 3.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF2636 PF11120.3 EMC89997.1 - 0.0064 15.9 1.5 0.0098 15.3 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2636) zf-ribbon_3 PF13248.1 EMC89997.1 - 0.026 13.7 5.0 0.045 12.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 EMC89997.1 - 0.039 13.5 1.4 4.1 7.0 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 EMC89997.1 - 0.045 13.4 5.9 0.21 11.2 4.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 EMC89997.1 - 0.063 12.7 1.4 0.32 10.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 EMC89997.1 - 0.09 12.7 0.5 15 5.7 0.1 2.4 2 0 0 2 2 2 0 zinc-finger DUF1936 PF09151.5 EMC89997.1 - 0.18 11.3 4.9 0.96 9.0 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) zf-nanos PF05741.8 EMC89997.1 - 0.29 11.1 0.2 0.29 11.1 0.2 1.6 2 0 0 2 2 2 0 Nanos RNA binding domain zinc_ribbon_5 PF13719.1 EMC89997.1 - 1 8.9 3.6 1 8.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMC89997.1 - 1.2 8.8 3.4 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 EMC89997.1 - 2.4 7.8 5.1 31 4.3 0.0 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-NADH-PPase PF09297.6 EMC89997.1 - 2.5 7.6 6.7 0.53 9.8 0.8 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF35_N PF12172.3 EMC89997.1 - 6.2 6.8 8.0 7.4 6.6 2.4 2.7 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) IMD PF08397.6 EMC89998.1 - 2e-77 259.4 6.4 4.1e-77 258.3 4.4 1.5 1 1 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 EMC89998.1 - 5.4e-11 41.8 0.0 9.2e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC89998.1 - 1.3e-06 27.8 0.0 2.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC89998.1 - 4.3e-06 26.0 0.0 8.4e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Rhabdo_M1 PF03342.8 EMC89998.1 - 0.0084 15.2 1.1 0.0084 15.2 0.7 1.8 2 1 0 2 2 2 1 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) DUF3510 PF12022.3 EMC89998.1 - 0.015 15.3 3.2 0.028 14.5 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) NusB PF01029.13 EMC89998.1 - 0.21 11.5 2.2 0.36 10.7 1.5 1.3 1 0 0 1 1 1 0 NusB family SYCE1 PF15233.1 EMC89998.1 - 0.89 9.4 8.1 0.28 11.0 2.9 1.9 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 PKD PF00801.15 EMC89999.1 - 7e-08 32.0 1.5 0.043 13.5 0.0 3.6 3 1 0 3 3 3 3 PKD domain DUF1193 PF06702.7 EMC90003.1 - 4.9e-117 389.0 0.1 1.2e-116 387.8 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1193) Fork_head PF00250.13 EMC90004.1 - 3.3e-38 129.6 0.2 4e-38 129.3 0.2 1.0 1 0 0 1 1 1 1 Fork head domain DUF1388 PF07142.7 EMC90005.1 - 6.3e-05 22.5 0.2 2 8.1 0.0 4.5 4 2 0 4 4 4 3 Repeat of unknown function (DUF1388) Ribosomal_S30 PF04758.9 EMC90006.1 - 0.15 11.8 0.1 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S30 zf-H2C2_2 PF13465.1 EMC90007.1 - 9.4e-16 57.2 11.3 1.7e-06 28.0 0.8 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90007.1 - 2.3e-10 40.1 21.4 4.8e-05 23.4 2.9 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90007.1 - 2.5e-05 24.2 19.2 0.00024 21.2 2.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EMC90007.1 - 0.0013 18.8 2.7 0.0013 18.8 1.9 3.2 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EMC90007.1 - 0.011 15.3 0.0 0.011 15.3 0.0 3.3 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 EMC90007.1 - 0.055 13.6 6.8 0.11 12.7 4.7 1.5 1 1 0 1 1 1 0 CHY zinc finger zf-C2H2_2 PF12756.2 EMC90007.1 - 0.1 12.6 9.9 3 8.0 3.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.11 EMC90007.1 - 0.7 10.0 0.2 0.7 10.0 0.1 3.1 3 0 0 3 3 3 0 C1 domain Endonuclease_7 PF02945.10 EMC90007.1 - 0.79 9.4 6.6 0.27 10.9 1.2 1.9 1 1 1 2 2 2 0 Recombination endonuclease VII zf-RING_5 PF14634.1 EMC90007.1 - 2.2 8.0 10.2 7.5 6.3 0.9 2.9 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.1 EMC90007.1 - 2.2 8.1 9.5 19 5.1 6.6 2.5 1 1 0 1 1 1 0 Ring finger domain zf-CCHC_2 PF13696.1 EMC90007.1 - 4.4 6.8 6.5 6.1 6.4 0.0 2.9 3 0 0 3 3 3 0 Zinc knuckle FYVE PF01363.16 EMC90007.1 - 5.2 7.0 14.0 13 5.7 9.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_6 PF13912.1 EMC90007.1 - 5.8 6.9 17.8 3.4 7.7 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met2 PF12907.2 EMC90007.1 - 8.1 6.5 10.6 12 5.9 0.9 3.2 3 0 0 3 3 3 0 Zinc-binding LIM PF00412.17 EMC90007.1 - 8.2 6.5 9.8 7.2 6.7 2.5 2.5 1 1 1 2 2 2 0 LIM domain BTB PF00651.26 EMC90008.1 - 2.7e-19 69.1 0.0 3e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.17 EMC90009.1 - 1.1e-11 43.9 0.3 1.1e-11 43.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSD3 PF15244.1 EMC90010.1 - 9.6e-33 114.0 12.6 3.3e-20 72.7 4.6 2.1 2 0 0 2 2 2 2 Hydroxy-steroid dehydrogenase CENP-F_N PF10481.4 EMC90011.1 - 7.8e-133 442.5 42.9 7.8e-133 442.5 29.7 16.3 6 3 9 17 17 17 2 Cenp-F N-terminal domain CENP-F_leu_zip PF10473.4 EMC90011.1 - 2e-46 157.3 66.3 1.2e-38 132.1 25.5 24.3 10 5 14 24 24 24 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-F_C_Rb_bdg PF10490.4 EMC90011.1 - 5.1e-07 28.9 0.0 1.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EMC90011.1 - 0.00098 18.6 62.8 0.00098 18.6 43.5 16.6 6 4 7 14 14 14 4 Intermediate filament protein Y_phosphatase PF00102.22 EMC90012.1 - 4.9e-75 251.8 0.6 9.3e-75 250.9 0.4 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.13 EMC90012.1 - 4.2e-23 81.9 0.4 1.4e-22 80.2 0.3 1.9 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 EMC90012.1 - 5.3e-21 74.4 0.1 1.4e-20 73.0 0.1 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.5 EMC90012.1 - 1.4e-09 37.9 0.7 3.9e-09 36.5 0.5 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.15 EMC90012.1 - 7.1e-05 22.3 0.0 0.0002 20.9 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC90012.1 - 0.0031 17.7 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family YcxB PF14317.1 EMC90012.1 - 0.12 11.6 0.1 0.33 10.2 0.1 1.7 1 0 0 1 1 1 0 YcxB-like protein DCAF15_WD40 PF14939.1 EMC90013.1 - 0.046 13.0 0.2 0.055 12.8 0.1 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat DUF1556 PF07590.6 EMC90013.1 - 0.23 11.6 2.6 1.3 9.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) SET PF00856.23 EMC90014.1 - 1.1e-11 45.2 0.1 2.3e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 EMC90014.1 - 1.4e-11 44.0 6.3 3.7e-11 42.7 4.4 1.7 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.1 EMC90014.1 - 5.3e-05 23.0 0.1 0.00015 21.5 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC90014.1 - 0.0078 16.7 0.2 0.12 13.0 0.1 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC90014.1 - 0.025 14.4 0.1 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMC90014.1 - 0.028 14.3 1.0 0.38 10.7 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMC90014.1 - 0.089 12.4 0.2 0.27 10.8 0.1 1.9 1 1 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 EMC90014.1 - 1.1 9.9 3.3 26 5.5 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HPD PF05044.7 EMC90015.1 - 3e-86 286.9 2.0 5.4e-86 286.1 1.4 1.4 1 0 0 1 1 1 1 Homeo-prospero domain Metal_resist PF13801.1 EMC90015.1 - 0.024 14.6 10.9 0.018 15.0 5.9 2.0 2 0 0 2 2 2 0 Heavy-metal resistance NifQ PF04891.7 EMC90015.1 - 0.048 13.8 2.6 1.5 8.9 0.0 3.3 3 0 0 3 3 3 0 NifQ DUF3138 PF11336.3 EMC90015.1 - 0.15 10.2 0.8 7 4.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4613 PF15390.1 EMC90015.1 - 0.15 10.2 5.9 0.23 9.5 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2968 PF11180.3 EMC90015.1 - 0.2 10.9 15.5 0.43 9.9 10.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4407 PF14362.1 EMC90015.1 - 0.82 8.5 8.9 1.2 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 EMC90015.1 - 0.93 7.8 3.7 1.5 7.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1640 PF07798.6 EMC90015.1 - 1.2 9.1 7.6 2.9 7.8 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) HemX PF04375.9 EMC90015.1 - 1.7 7.1 11.3 3 6.3 7.8 1.3 1 0 0 1 1 1 0 HemX Nop25 PF09805.4 EMC90015.1 - 2 8.5 17.4 3.8 7.5 11.9 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) FliD_N PF02465.13 EMC90015.1 - 3.6 7.9 6.9 61 4.0 5.1 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 EMC90015.1 - 5.1 6.6 11.4 9.4 5.7 7.9 1.3 1 0 0 1 1 1 0 IncA protein LETM1 PF07766.8 EMC90016.1 - 1.9e-70 237.0 6.4 4.3e-70 235.8 4.5 1.6 1 1 0 1 1 1 1 LETM1-like protein Pkinase PF00069.20 EMC90017.1 - 1.9e-27 96.0 0.0 2.9e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.13 EMC90017.1 - 8.8e-21 73.5 3.0 1.7e-20 72.6 2.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase_Tyr PF07714.12 EMC90017.1 - 6.3e-13 48.3 0.0 5.5e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.19 EMC90017.1 - 1.5e-11 44.0 0.4 3e-11 43.1 0.3 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 EMC90017.1 - 9.5e-05 21.4 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Exo_endo_phos PF03372.18 EMC90018.1 - 1.6e-24 87.2 0.0 2.6e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EMC90019.1 - 1.3e-25 89.8 26.6 1.3e-25 89.8 18.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Herpes_UL45 PF05473.7 EMC90019.1 - 0.22 10.9 0.1 0.22 10.9 0.1 3.0 3 1 0 3 3 3 0 UL45 protein TatD_DNase PF01026.16 EMC90020.1 - 1.7e-47 161.7 0.0 2.1e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Flexi_CP_N PF08358.5 EMC90020.1 - 0.044 13.5 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Carlavirus coat Mis14 PF08641.7 EMC90021.1 - 3.7e-17 62.6 1.2 6.2e-17 61.9 0.8 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like bZIP_1 PF00170.16 EMC90022.1 - 4e-13 49.1 12.2 5e-13 48.7 8.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC90022.1 - 6.2e-10 38.7 14.3 7.8e-10 38.4 9.9 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC90022.1 - 5.4e-09 36.2 9.6 7e-09 35.8 6.6 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.13 EMC90022.1 - 8.2e-06 25.4 3.0 1.7e-05 24.4 2.1 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper HAP1_N PF04849.8 EMC90022.1 - 0.00058 18.9 5.5 0.00065 18.7 3.8 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TPD52 PF04201.10 EMC90022.1 - 0.0038 16.9 3.1 0.0045 16.7 2.2 1.2 1 0 0 1 1 1 1 Tumour protein D52 family DivIC PF04977.10 EMC90022.1 - 0.0074 15.7 4.7 0.0074 15.7 3.3 1.5 1 1 0 1 1 1 1 Septum formation initiator DUF3450 PF11932.3 EMC90022.1 - 0.0094 15.2 1.0 0.0094 15.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Macoilin PF09726.4 EMC90022.1 - 0.01 14.1 3.6 0.011 14.1 2.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DASH_Spc19 PF08287.6 EMC90022.1 - 0.013 15.1 0.1 0.013 15.1 0.1 2.0 1 1 1 2 2 2 0 Spc19 BLOC1_2 PF10046.4 EMC90022.1 - 0.014 15.5 1.0 0.018 15.1 0.7 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phlebovirus_NSM PF07246.6 EMC90022.1 - 0.015 14.5 2.7 0.015 14.4 1.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMF_TATA_bd PF12325.3 EMC90022.1 - 0.016 14.9 5.6 0.016 14.9 3.9 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 EMC90022.1 - 0.018 13.5 4.4 0.02 13.4 3.1 1.0 1 0 0 1 1 1 0 AAA domain DivIVA PF05103.8 EMC90022.1 - 0.02 14.9 2.1 0.02 14.9 1.4 1.9 1 1 1 2 2 2 0 DivIVA protein TLE_N PF03920.10 EMC90022.1 - 0.027 14.2 2.3 0.034 13.9 1.6 1.2 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain COG5 PF10392.4 EMC90022.1 - 0.027 14.4 1.0 0.032 14.1 0.7 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF342 PF03961.8 EMC90022.1 - 0.044 12.2 4.0 0.048 12.0 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 EMC90022.1 - 0.053 13.3 10.6 0.071 12.9 7.3 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.6 EMC90022.1 - 0.056 10.9 1.4 0.062 10.8 1.0 1.0 1 0 0 1 1 1 0 Prominin APG6 PF04111.7 EMC90022.1 - 0.06 12.3 5.9 0.069 12.1 4.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 EMC90022.1 - 0.061 11.5 2.3 0.061 11.5 1.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_Rpb1_6 PF04992.9 EMC90022.1 - 0.063 13.0 2.5 0.076 12.7 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Ribosomal_L30_N PF08079.7 EMC90022.1 - 0.085 12.8 10.6 0.11 12.4 7.3 1.2 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain ADIP PF11559.3 EMC90022.1 - 0.094 12.6 8.7 0.12 12.3 6.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.4 EMC90022.1 - 0.096 12.6 8.2 0.1 12.5 5.7 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1465 PF07323.7 EMC90022.1 - 0.096 12.2 2.9 0.11 12.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Seryl_tRNA_N PF02403.17 EMC90022.1 - 0.11 12.5 6.7 0.14 12.1 4.6 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SYCE1 PF15233.1 EMC90022.1 - 0.11 12.4 6.6 0.14 12.1 4.1 1.5 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 Microtub_assoc PF07989.6 EMC90022.1 - 0.11 12.3 4.6 0.18 11.6 3.2 1.4 1 0 0 1 1 1 0 Microtubule associated CNPase PF05881.7 EMC90022.1 - 0.13 11.6 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) DUF2009 PF09418.5 EMC90022.1 - 0.14 10.9 1.7 0.15 10.7 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) tRNA-synt_2c PF01411.14 EMC90022.1 - 0.14 10.4 2.8 0.16 10.2 1.9 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) TMCO5 PF14992.1 EMC90022.1 - 0.15 11.1 5.7 0.18 10.8 3.9 1.1 1 0 0 1 1 1 0 TMCO5 family DUF1515 PF07439.6 EMC90022.1 - 0.17 11.7 2.1 0.22 11.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4200 PF13863.1 EMC90022.1 - 0.19 11.6 10.4 0.3 11.0 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 EMC90022.1 - 0.2 11.3 6.8 0.25 10.9 4.7 1.1 1 0 0 1 1 1 0 Mnd1 family Tnp_P_element PF12017.3 EMC90022.1 - 0.2 10.8 1.9 0.23 10.6 1.1 1.3 1 1 0 1 1 1 0 Transposase protein CCDC92 PF14916.1 EMC90022.1 - 0.2 11.2 4.4 0.42 10.2 2.8 1.8 1 1 0 1 1 1 0 Coiled-coil domain of unknown function DUF2681 PF10883.3 EMC90022.1 - 0.23 11.6 6.9 1.2 9.4 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) IncA PF04156.9 EMC90022.1 - 0.27 10.8 7.8 0.34 10.4 5.4 1.2 1 0 0 1 1 1 0 IncA protein DUF4613 PF15390.1 EMC90022.1 - 0.33 9.0 2.3 0.36 8.9 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Cnd1_N PF12922.2 EMC90022.1 - 0.34 10.5 3.4 5.5 6.5 1.5 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF4140 PF13600.1 EMC90022.1 - 0.36 11.2 5.2 0.5 10.8 3.6 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EMC90022.1 - 0.42 10.9 6.7 0.46 10.8 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EMC90022.1 - 0.57 9.9 12.4 1.5 8.6 8.7 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 EMC90022.1 - 0.59 7.9 3.5 0.64 7.8 2.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EMC90022.1 - 0.88 8.4 3.3 0.98 8.3 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 EMC90022.1 - 0.9 7.5 4.9 1.1 7.2 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1640 PF07798.6 EMC90022.1 - 0.93 9.5 6.3 1.1 9.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4094 PF13334.1 EMC90022.1 - 1.3 9.4 4.3 1.5 9.2 2.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TMPIT PF07851.8 EMC90022.1 - 1.6 7.7 3.6 1.9 7.4 2.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Bap31 PF05529.7 EMC90022.1 - 2.6 7.4 7.1 3 7.2 4.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like RRF PF01765.14 EMC90022.1 - 4.8 6.6 10.0 6.3 6.2 6.9 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Spc24 PF08286.6 EMC90022.1 - 5.6 6.6 7.8 15 5.2 5.4 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2762 PF10960.3 EMC90022.1 - 6.3 6.5 10.5 5.9 6.6 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) bZIP_1 PF00170.16 EMC90023.1 - 1.4e-11 44.1 19.6 2.8e-11 43.1 13.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC90023.1 - 1e-10 41.2 18.9 1.6e-10 40.6 13.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMC90023.1 - 7.6e-08 32.5 7.9 7.6e-08 32.5 5.5 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor SNAPc19 PF15497.1 EMC90023.1 - 0.0022 18.1 1.5 0.0022 18.1 1.0 2.0 2 1 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 AOX PF01786.12 EMC90023.1 - 0.018 14.4 0.2 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Alternative oxidase Vps51 PF08700.6 EMC90023.1 - 0.075 12.8 2.5 0.17 11.7 1.7 1.6 1 0 0 1 1 1 0 Vps51/Vps67 DivIC PF04977.10 EMC90023.1 - 0.077 12.4 6.6 0.15 11.6 4.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.4 EMC90023.1 - 0.39 8.9 10.8 0.49 8.6 7.5 1.0 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 EMC90023.1 - 0.45 8.2 3.9 0.51 8.1 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EMC90023.1 - 1.5 8.5 8.3 1.4 8.5 4.8 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ribosomal_L6e PF01159.14 EMC90023.1 - 1.6 9.0 7.7 4.2 7.6 5.3 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e Seryl_tRNA_N PF02403.17 EMC90023.1 - 3 7.8 13.1 4.9 7.2 9.1 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EMC90023.1 - 3.7 7.1 7.5 5.4 6.5 5.2 1.4 1 0 0 1 1 1 0 IncA protein Cyt-b5 PF00173.23 EMC90024.1 - 8.3e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMEM206 PF15122.1 EMC90025.1 - 7.2e-176 583.2 3.4 8.3e-176 583.0 2.4 1.0 1 0 0 1 1 1 1 TMEM206 protein family B56 PF01603.15 EMC90026.1 - 8.7e-177 587.7 9.2 1e-176 587.5 6.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cytochrom_B561 PF03188.11 EMC90026.1 - 0.042 13.6 0.3 0.069 12.9 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 WD40 PF00400.27 EMC90027.1 - 7.2e-35 117.6 10.7 3.9e-09 36.0 0.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat HEAT_2 PF13646.1 EMC90028.1 - 1.7e-05 24.9 3.8 0.32 11.3 0.0 4.5 2 1 2 5 5 5 2 HEAT repeats TPR_6 PF13174.1 EMC90028.1 - 0.0003 21.0 1.0 2 9.0 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3453 PF11935.3 EMC90028.1 - 0.011 15.1 4.4 0.024 14.0 0.1 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3453) TPR_2 PF07719.12 EMC90028.1 - 0.15 12.0 0.8 7.9 6.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FANCI_S2 PF14676.1 EMC90028.1 - 0.53 10.1 6.4 1.1 9.1 0.3 2.6 2 0 0 2 2 2 0 FANCI solenoid 2 WD40 PF00400.27 EMC90031.1 - 2.2e-39 131.9 15.0 3.4e-05 23.5 0.0 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 EMC90031.1 - 0.031 14.0 0.0 0.16 11.6 0.0 2.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A TFIIS_C PF01096.13 EMC90032.1 - 0.00022 20.7 0.3 0.00022 20.7 0.2 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMC90032.1 - 0.0037 16.9 5.9 0.0063 16.1 1.0 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit FerA PF08165.6 EMC90032.1 - 0.11 12.2 0.1 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 FerA (NUC095) domain DUF3716 PF12511.3 EMC90032.1 - 2.1 8.0 5.9 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) RhoGAP PF00620.22 EMC90034.1 - 2.3e-17 63.0 0.1 3.5e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 RhoGAP domain TFIIE_beta PF02186.10 EMC90037.1 - 1.3e-24 85.8 0.2 3.5e-24 84.5 0.1 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF1880 PF08976.6 EMC90037.1 - 0.046 13.8 0.2 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) NusG PF02357.14 EMC90037.1 - 0.11 12.7 0.1 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription termination factor nusG PDZ PF00595.19 EMC90037.1 - 0.11 12.6 0.1 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Hexapep PF00132.19 EMC90038.1 - 5e-10 38.4 20.5 3.2e-05 23.2 2.1 4.5 5 1 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Yeast-kill-tox PF09207.6 EMC90038.1 - 0.065 13.6 0.6 0.1 13.0 0.4 1.3 1 0 0 1 1 1 0 Yeast killer toxin Hexapep_2 PF14602.1 EMC90038.1 - 8.2 6.0 13.5 3.9 7.1 3.0 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase PHO4 PF01384.15 EMC90039.1 - 5.6e-129 429.4 0.0 1.1e-128 428.4 0.0 1.5 1 1 0 1 1 1 1 Phosphate transporter family Vpu PF00558.14 EMC90039.1 - 0.019 14.4 0.1 0.019 14.4 0.1 2.0 2 0 0 2 2 2 0 Vpu protein Pkinase_Tyr PF07714.12 EMC90041.1 - 2e-08 33.6 0.0 4.3e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EMC90041.1 - 2.2e-05 23.7 0.0 0.0031 16.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain PIP49_C PF12260.3 EMC90041.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF1624 PF07786.7 EMC90042.1 - 1.9e-07 30.6 1.2 1.9e-07 30.6 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1624) GWT1 PF06423.7 EMC90042.1 - 4.6 7.3 9.2 0.2 11.7 1.1 2.5 3 0 0 3 3 3 0 GWT1 Yae1_N PF09811.4 EMC90043.1 - 5.8e-26 89.7 164.6 1.5e+04 -130.0 114.1 10.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal CHGN PF05679.11 EMC90044.1 - 4.9e-50 170.6 0.0 6e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 EMC90044.1 - 1.4e-10 40.4 0.3 2.9e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC90044.1 - 1.2e-09 37.7 0.0 2.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 IncA PF04156.9 EMC90044.1 - 0.0071 15.9 0.3 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 IncA protein THOC7 PF05615.8 EMC90044.1 - 0.0078 16.4 1.8 0.016 15.5 0.2 2.1 2 0 0 2 2 2 1 Tho complex subunit 7 Pkinase PF00069.20 EMC90045.1 - 7.4e-75 251.4 0.0 1e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90045.1 - 9.5e-41 139.5 0.0 3.5e-40 137.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC90045.1 - 1.5e-09 37.2 0.8 4.8e-07 29.0 0.0 2.9 2 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 EMC90045.1 - 0.0026 16.8 0.1 0.0064 15.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC90045.1 - 0.01 15.5 0.1 0.21 11.2 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family NUC153 PF08159.7 EMC90045.1 - 0.053 13.1 0.1 12 5.5 0.0 2.8 2 0 0 2 2 2 0 NUC153 domain zinc_ribbon_6 PF14599.1 EMC90046.1 - 3.6e-30 103.5 0.7 3.6e-30 103.5 0.5 3.3 2 1 1 3 3 1 1 Zinc-ribbon zf-RING_2 PF13639.1 EMC90046.1 - 7.5e-11 41.6 6.5 7.5e-11 41.6 4.5 3.9 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMC90046.1 - 3.7e-09 36.4 5.7 3.7e-09 36.4 4.0 4.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC90046.1 - 1.3e-07 31.0 4.5 1.3e-07 31.0 3.1 4.4 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC90046.1 - 2.9e-07 30.0 5.8 2.9e-07 30.0 4.0 5.0 2 2 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC90046.1 - 9.6e-07 28.4 5.4 9.6e-07 28.4 3.7 5.6 2 2 2 4 4 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMC90046.1 - 3.7e-06 26.5 1.7 3.7e-06 26.5 1.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EMC90046.1 - 0.00011 21.7 2.9 0.00011 21.7 2.0 4.4 4 1 1 5 5 4 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EMC90046.1 - 0.015 15.0 0.7 0.015 15.0 0.5 2.9 3 2 0 3 3 3 0 Zinc-binding RING-finger ASFV_p27 PF06556.6 EMC90046.1 - 0.23 11.3 1.9 1.8 8.4 1.5 2.0 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus DUF2367 PF10164.4 EMC90046.1 - 3 7.7 6.7 1.2 9.0 2.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) TMEM154 PF15102.1 EMC90047.1 - 6.9e-05 22.5 0.0 7.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 EMC90047.1 - 8.9e-05 22.8 0.3 0.00013 22.2 0.2 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMC90047.1 - 9.2e-05 22.6 0.3 9.2e-05 22.6 0.2 1.5 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator hEGF PF12661.2 EMC90047.1 - 0.00031 20.6 1.6 0.00031 20.6 1.1 2.8 3 1 0 2 2 2 1 Human growth factor-like EGF FAM163 PF15069.1 EMC90047.1 - 0.00078 20.0 1.0 0.0014 19.2 0.7 1.4 1 0 0 1 1 1 1 FAM163 family Herpes_gE PF02480.11 EMC90047.1 - 0.00081 17.7 0.0 0.0011 17.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Vpu PF00558.14 EMC90047.1 - 0.00094 18.6 0.2 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 Vpu protein EGF PF00008.22 EMC90047.1 - 0.0062 16.4 2.8 0.0062 16.4 1.9 2.4 2 0 0 2 2 1 1 EGF-like domain PAG PF15347.1 EMC90047.1 - 0.0076 15.3 0.0 0.0084 15.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched EGF_2 PF07974.8 EMC90047.1 - 0.01 15.9 3.2 0.01 15.9 2.2 2.6 2 1 0 2 2 2 0 EGF-like domain FAM176 PF14851.1 EMC90047.1 - 0.012 15.3 0.2 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Rax2 PF12768.2 EMC90047.1 - 0.013 14.7 0.1 0.017 14.3 0.1 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3609 PF12259.3 EMC90047.1 - 0.018 13.6 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) LST1 PF05083.8 EMC90047.1 - 0.022 14.7 0.5 0.022 14.7 0.3 1.8 2 0 0 2 2 2 0 LST-1 protein Laminin_EGF PF00053.19 EMC90047.1 - 0.025 14.5 3.7 0.025 14.5 2.6 2.3 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) 7tm_1 PF00001.16 EMC90047.1 - 0.033 13.3 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) IncA PF04156.9 EMC90047.1 - 0.052 13.1 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 IncA protein FixQ PF05545.6 EMC90047.1 - 0.057 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Protocadherin PF08374.6 EMC90047.1 - 0.057 13.0 0.1 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Protocadherin SieB PF14163.1 EMC90047.1 - 0.066 12.7 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B CD34_antigen PF06365.7 EMC90047.1 - 0.071 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1191 PF06697.7 EMC90047.1 - 0.088 11.6 0.2 0.11 11.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) DAG1 PF05454.6 EMC90047.1 - 0.12 11.5 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) AJAP1_PANP_C PF15298.1 EMC90047.1 - 0.15 11.9 1.6 0.21 11.4 1.1 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ATP1G1_PLM_MAT8 PF02038.11 EMC90048.1 - 1.7e-16 58.9 0.0 2.6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family Plectin PF00681.15 EMC90049.1 - 0.13 11.7 6.5 47 3.6 0.0 5.0 5 1 0 5 5 5 0 Plectin repeat DUF3651 PF12371.3 EMC90049.1 - 2 8.4 16.2 7 6.7 2.8 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3651) Plexin_cytopl PF08337.7 EMC90053.1 - 6e-246 816.9 9.1 8.6e-246 816.4 6.3 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.14 EMC90053.1 - 1.8e-35 122.3 9.9 7e-35 120.3 3.3 2.3 1 1 1 2 2 2 2 Sema domain TIG PF01833.19 EMC90053.1 - 4.7e-34 116.2 15.0 8.8e-11 41.6 1.8 6.0 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 EMC90053.1 - 6.5e-15 55.0 52.8 7e-11 42.1 11.6 3.6 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.14 EMC90053.1 - 1.1e-05 25.2 0.0 0.00028 20.5 0.0 2.9 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Amino_oxidase PF01593.19 EMC90054.1 - 1.2e-69 235.5 0.1 1.4e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMC90054.1 - 1.8e-15 56.7 0.1 3.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMC90054.1 - 3.4e-07 29.4 0.3 9.4e-07 28.0 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMC90054.1 - 9.9e-07 29.0 2.2 2.5e-06 27.7 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMC90054.1 - 2.2e-06 26.9 0.0 3.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMC90054.1 - 1.7e-05 24.7 0.0 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMC90054.1 - 2e-05 24.2 1.0 2.9e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EMC90054.1 - 2.8e-05 23.1 0.2 5.1e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EMC90054.1 - 3.7e-05 22.9 0.0 6.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMC90054.1 - 0.00013 22.1 0.1 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMC90054.1 - 0.0003 19.3 0.2 0.0006 18.3 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EMC90054.1 - 0.0007 18.6 0.1 0.18 10.6 0.1 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EMC90054.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.14 EMC90054.1 - 0.0064 14.7 0.0 0.01 14.0 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 EMC90054.1 - 0.0071 15.0 0.8 0.014 14.0 0.3 1.6 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EMC90054.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EMC90054.1 - 0.047 13.6 0.1 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EMC90054.1 - 0.051 13.2 0.1 0.091 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMC90054.1 - 0.067 12.0 0.1 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 EMC90054.1 - 0.087 12.2 1.3 0.35 10.2 0.2 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EMC90054.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EMC90054.1 - 0.13 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPRY PF00622.23 EMC90056.1 - 3.5e-25 88.5 0.4 4e-25 88.2 0.3 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 EMC90056.1 - 7.1e-20 70.2 0.4 8e-19 66.9 0.1 2.2 2 0 0 2 2 2 1 SPRY-associated domain PRY PF13765.1 EMC90058.1 - 2.6e-18 65.2 0.3 5.8e-18 64.1 0.2 1.6 1 0 0 1 1 1 1 SPRY-associated domain V-set PF07686.12 EMC90058.1 - 8.2e-13 48.2 0.0 1.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC90058.1 - 2.3e-08 33.7 0.0 1.1e-06 28.4 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin I-set domain SPRY PF00622.23 EMC90058.1 - 5.1e-08 33.0 0.2 8.5e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Ig_3 PF13927.1 EMC90058.1 - 7.1e-06 26.4 0.0 0.0073 16.7 0.0 3.2 2 2 1 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.1 EMC90058.1 - 0.00011 22.2 0.0 0.00054 20.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC90058.1 - 0.0012 18.6 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC90058.1 - 0.092 12.8 0.0 1.5 9.0 0.0 2.6 1 1 0 1 1 1 0 Immunoglobulin domain Porin_O_P PF07396.6 EMC90058.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Phosphate-selective porin O and P SPRY PF00622.23 EMC90059.1 - 1.8e-19 70.0 0.0 3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 EMC90059.1 - 1.4e-17 62.8 0.2 4.8e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 SPRY-associated domain zf-B_box PF00643.19 EMC90059.1 - 5.8e-09 35.7 0.3 5.8e-09 35.7 0.2 2.9 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_3 PF13920.1 EMC90059.1 - 1.4e-05 24.6 4.1 1.4e-05 24.6 2.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC90059.1 - 3.3e-05 23.4 3.4 3.3e-05 23.4 2.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC90059.1 - 0.00011 22.1 5.7 0.00011 22.1 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC90059.1 - 0.00013 21.6 5.5 0.00013 21.6 3.8 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Fer2 PF00111.22 EMC90059.1 - 0.039 13.6 5.4 0.26 11.0 1.4 2.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain AAA_13 PF13166.1 EMC90059.1 - 0.076 11.4 4.5 0.1 11.0 3.1 1.0 1 0 0 1 1 1 0 AAA domain Fer2_3 PF13085.1 EMC90059.1 - 0.13 12.0 2.0 0.37 10.6 1.4 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain V_ATPase_I PF01496.14 EMC90059.1 - 1.7 6.4 3.9 2.1 6.0 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_4 PF14570.1 EMC90059.1 - 2 8.0 9.0 0.35 10.4 1.1 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EMC90059.1 - 2.7 7.8 7.3 3.9 7.2 0.9 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF342 PF03961.8 EMC90059.1 - 4.4 5.6 7.1 6.3 5.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 EMC90059.1 - 8.8 6.2 10.0 16 5.4 6.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 EMC90059.1 - 9.2 5.3 8.1 13 4.8 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-H2C2_2 PF13465.1 EMC90061.1 - 3.3e-31 106.0 21.5 1.5e-08 34.4 0.2 4.3 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90061.1 - 3.1e-17 61.7 33.5 1.4e-05 25.1 0.1 5.7 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90061.1 - 1.2e-09 37.7 24.7 0.0068 16.6 0.4 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC90061.1 - 1.3e-07 31.2 17.8 0.00051 19.8 0.1 5.0 5 0 0 5 5 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90061.1 - 4e-06 26.7 0.8 2.2 8.5 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMC90061.1 - 3e-05 24.0 12.5 0.02 15.0 0.7 3.7 1 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EMC90061.1 - 3.3e-05 23.9 5.1 0.091 12.9 0.0 4.4 4 1 0 4 4 4 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EMC90061.1 - 3.5e-05 23.6 15.5 0.036 14.0 1.7 4.2 2 1 1 3 3 3 2 Zinc ribbon domain CpXC PF14353.1 EMC90061.1 - 9.4e-05 22.3 10.5 0.18 11.7 0.0 3.8 2 2 1 3 3 3 1 CpXC protein DZR PF12773.2 EMC90061.1 - 0.00012 21.8 3.6 0.00012 21.8 2.5 3.1 1 1 1 2 2 2 1 Double zinc ribbon zf-RING_3 PF14369.1 EMC90061.1 - 0.00038 20.3 10.7 0.79 9.7 0.1 4.1 4 0 0 4 4 4 1 zinc-finger XPA_N PF01286.13 EMC90061.1 - 0.00085 18.9 12.2 0.22 11.2 0.0 4.1 4 0 0 4 4 4 2 XPA protein N-terminal zf-LYAR PF08790.6 EMC90061.1 - 0.0027 17.3 5.1 1.4 8.6 0.2 3.6 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger TF_Zn_Ribbon PF08271.7 EMC90061.1 - 0.0029 16.8 0.4 0.0029 16.8 0.2 3.5 3 1 0 3 3 2 2 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 EMC90061.1 - 0.003 16.9 17.9 0.15 11.5 1.8 4.4 3 3 2 5 5 5 2 zinc-ribbon domain zf-CHY PF05495.7 EMC90061.1 - 0.0041 17.2 1.2 0.0041 17.2 0.8 2.4 1 1 0 2 2 2 1 CHY zinc finger Terminase_GpA PF05876.7 EMC90061.1 - 0.0078 14.6 0.6 0.0078 14.6 0.4 2.0 1 1 1 2 2 2 1 Phage terminase large subunit (GpA) zf-ribbon_3 PF13248.1 EMC90061.1 - 0.0089 15.2 21.0 1.2 8.4 0.1 4.6 4 1 0 4 4 4 1 zinc-ribbon domain zf-CSL PF05207.8 EMC90061.1 - 0.014 14.9 4.1 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 CSL zinc finger LIM PF00412.17 EMC90061.1 - 0.014 15.4 0.9 0.014 15.4 0.7 3.2 3 1 0 3 3 2 0 LIM domain UPF0547 PF10571.4 EMC90061.1 - 0.015 14.9 17.1 3 7.6 0.2 4.2 4 1 0 4 4 3 0 Uncharacterised protein family UPF0547 zf-DNA_Pol PF08996.5 EMC90061.1 - 0.015 14.6 7.0 0.048 13.0 0.3 2.1 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger TerY-C PF15616.1 EMC90061.1 - 0.016 15.1 0.6 0.016 15.1 0.4 2.5 1 1 2 3 3 3 0 TerY-C metal binding domain C1_4 PF07975.7 EMC90061.1 - 0.019 14.9 9.8 18 5.4 0.0 3.9 1 1 3 4 4 4 0 TFIIH C1-like domain C1_3 PF07649.7 EMC90061.1 - 0.02 14.9 8.2 6.3 6.9 0.1 4.3 4 0 0 4 4 4 0 C1-like domain Elf1 PF05129.8 EMC90061.1 - 0.02 14.5 0.8 0.02 14.5 0.6 2.9 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EMC90061.1 - 0.024 14.4 19.8 0.24 11.2 3.3 3.5 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zf-IS66 PF13005.2 EMC90061.1 - 0.026 14.4 12.6 3.8 7.5 0.0 4.3 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-3CxxC PF13695.1 EMC90061.1 - 0.032 14.4 5.3 4 7.7 0.6 3.1 1 1 2 3 3 3 0 Zinc-binding domain TFIIS_C PF01096.13 EMC90061.1 - 0.033 13.8 12.8 8.7 6.0 0.0 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) DUF3268 PF11672.3 EMC90061.1 - 0.037 14.0 6.3 0.59 10.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) zf-ISL3 PF14690.1 EMC90061.1 - 0.041 13.9 18.2 1.2 9.2 0.4 4.4 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.14 EMC90061.1 - 0.042 13.5 8.7 0.36 10.5 0.4 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 EMC90061.1 - 0.05 13.3 9.5 9.7 6.0 0.0 4.6 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.11 EMC90061.1 - 0.073 12.9 12.5 3.3 7.6 0.0 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger DUF164 PF02591.10 EMC90061.1 - 0.075 12.8 8.6 12 5.8 0.1 3.9 4 0 0 4 4 4 0 Putative zinc ribbon domain FYDLN_acid PF09538.5 EMC90061.1 - 0.082 13.4 8.1 3 8.4 0.1 3.3 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_recom PF13408.1 EMC90061.1 - 0.083 13.1 15.7 16 5.8 5.2 3.7 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain HNH PF01844.18 EMC90061.1 - 0.089 12.6 3.1 3.4 7.6 0.4 3.5 2 1 1 3 3 3 0 HNH endonuclease A2L_zn_ribbon PF08792.5 EMC90061.1 - 0.11 11.9 15.8 0.55 9.7 0.1 4.3 4 0 0 4 4 4 0 A2L zinc ribbon domain Prok-RING_4 PF14447.1 EMC90061.1 - 0.14 11.7 4.0 3.1 7.4 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Rep_fac-A_C PF08646.5 EMC90061.1 - 0.14 11.8 5.2 0.16 11.6 0.0 2.7 1 1 1 3 3 3 0 Replication factor-A C terminal domain Lar_restr_allev PF14354.1 EMC90061.1 - 0.15 12.4 11.9 0.87 9.9 3.3 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-C2HC_2 PF13913.1 EMC90061.1 - 0.16 11.7 0.8 0.16 11.7 0.5 4.0 4 0 0 4 4 3 0 zinc-finger of a C2HC-type Cytochrom_CIII PF02085.11 EMC90061.1 - 0.16 12.0 6.4 0.54 10.3 4.4 1.8 1 1 0 1 1 1 0 Class III cytochrome C family zinc_ribbon_5 PF13719.1 EMC90061.1 - 0.21 11.1 15.4 7.8 6.1 0.1 4.2 3 1 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.7 EMC90061.1 - 0.27 10.9 17.5 0.36 10.5 0.3 3.8 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zinc-ribbons_6 PF07191.7 EMC90061.1 - 0.3 10.9 10.3 0.18 11.5 0.3 3.3 1 1 3 4 4 4 0 zinc-ribbons DUF329 PF03884.9 EMC90061.1 - 0.3 10.6 13.4 9.5 5.8 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF329) zf-C4_Topoisom PF01396.14 EMC90061.1 - 0.3 10.6 18.2 1.9 8.0 0.1 4.5 3 1 1 4 4 4 0 Topoisomerase DNA binding C4 zinc finger zf-HIT PF04438.11 EMC90061.1 - 0.32 10.6 18.4 2.7 7.7 0.2 4.3 4 0 0 4 4 4 0 HIT zinc finger zinc_ribbon_4 PF13717.1 EMC90061.1 - 0.34 10.6 15.1 8.8 6.1 0.1 4.2 3 1 0 3 3 3 0 zinc-ribbon domain Sgf11 PF08209.6 EMC90061.1 - 0.5 9.7 11.7 4.3 6.7 0.0 4.2 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) Arc_trans_TRASH PF08394.5 EMC90061.1 - 0.57 10.3 8.2 22 5.3 0.0 4.2 1 1 3 4 4 4 0 Archaeal TRASH domain GcpE PF04551.9 EMC90061.1 - 0.59 8.8 2.7 0.67 8.6 0.0 2.2 1 1 2 3 3 3 0 GcpE protein SprT-like PF10263.4 EMC90061.1 - 0.62 9.6 7.9 0.4 10.3 2.1 2.1 1 1 1 2 2 2 0 SprT-like family zf-trcl PF13451.1 EMC90061.1 - 0.68 9.6 14.6 15 5.3 1.3 3.8 2 2 0 2 2 2 0 Probable zinc-binding domain GFA PF04828.9 EMC90061.1 - 0.76 9.7 12.4 4.1 7.4 0.1 3.5 1 1 3 4 4 3 0 Glutathione-dependent formaldehyde-activating enzyme Fer4_9 PF13187.1 EMC90061.1 - 0.85 9.9 9.4 5.7 7.2 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain DNA_RNApol_7kD PF03604.8 EMC90061.1 - 0.94 9.0 12.6 12 5.4 0.1 4.3 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_5 PF14634.1 EMC90061.1 - 1 9.1 10.9 4.2 7.1 3.7 3.3 2 1 1 3 3 3 0 zinc-RING finger domain IBR PF01485.16 EMC90061.1 - 2.2 8.1 11.3 9.5 6.1 3.6 3.3 2 1 0 2 2 2 0 IBR domain zf-Mss51 PF13824.1 EMC90061.1 - 3.1 7.7 17.5 3.1 7.7 0.2 3.9 2 1 2 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 FYVE PF01363.16 EMC90061.1 - 3.1 7.7 14.1 1.9 8.4 1.7 3.0 1 1 1 2 2 2 0 FYVE zinc finger YhfH PF14149.1 EMC90061.1 - 4.7 7.0 15.9 11 5.9 0.0 4.3 5 0 0 5 5 3 0 YhfH-like protein zf-TRAF PF02176.13 EMC90061.1 - 4.9 7.6 9.8 4.6 7.7 0.2 2.6 2 1 1 3 3 2 0 TRAF-type zinc finger CoiA PF06054.6 EMC90061.1 - 5.2 5.8 7.1 4.2 6.1 0.8 3.1 1 1 2 3 3 3 0 Competence protein CoiA-like family Cript PF10235.4 EMC90061.1 - 6.9 7.0 10.0 10 6.5 0.0 3.7 4 1 0 4 4 3 0 Microtubule-associated protein CRIPT zf-TFIIB PF13453.1 EMC90061.1 - 7 5.9 16.5 1.8 7.7 1.5 3.5 2 1 1 3 3 3 0 Transcription factor zinc-finger DUF1272 PF06906.6 EMC90061.1 - 7 6.5 12.3 40 4.1 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1272) Zn_Tnp_IS91 PF14319.1 EMC90061.1 - 7.1 6.1 11.6 16 5.0 1.2 3.6 1 1 1 2 2 2 0 Transposase zinc-binding domain PhnA_Zn_Ribbon PF08274.7 EMC90061.1 - 7.2 6.4 15.2 27 4.6 0.1 4.2 4 0 0 4 4 4 0 PhnA Zinc-Ribbon PHD PF00628.24 EMC90061.1 - 9.7 5.9 12.8 31 4.3 1.3 3.9 2 1 2 4 4 4 0 PHD-finger OrfB_Zn_ribbon PF07282.6 EMC90061.1 - 10 5.8 15.4 1.5 8.5 0.9 3.7 1 1 3 4 4 4 0 Putative transposase DNA-binding domain DUF4171 PF13775.1 EMC90062.1 - 3.7e-39 133.8 24.7 3.7e-39 133.8 17.1 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4171) HMG_box PF00505.14 EMC90062.1 - 5.1e-15 55.4 2.4 5.1e-15 55.4 1.7 3.4 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC90062.1 - 3.2e-09 37.0 2.2 3.2e-09 37.0 1.5 2.8 2 1 0 2 2 2 1 HMG-box domain p53-inducible11 PF14936.1 EMC90062.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 VHS PF00790.14 EMC90063.1 - 1e-45 154.8 0.0 1.9e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EMC90063.1 - 4.4e-33 113.2 0.9 9e-33 112.2 0.6 1.5 1 0 0 1 1 1 1 GAT domain Baculo_PEP_C PF04513.7 EMC90063.1 - 0.16 11.7 2.0 1.2 8.9 0.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Heme_oxygenase PF01126.15 EMC90065.1 - 7.6e-80 267.3 2.2 9.7e-80 266.9 1.5 1.1 1 0 0 1 1 1 1 Heme oxygenase AAA_assoc_C PF09821.4 EMC90065.1 - 0.031 14.5 0.9 0.048 13.9 0.1 1.7 2 0 0 2 2 2 0 C-terminal AAA-associated domain FliE PF02049.13 EMC90065.1 - 0.17 11.9 0.9 0.44 10.6 0.6 1.7 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Mod_r PF07200.8 EMC90065.1 - 0.33 10.8 6.9 0.25 11.2 1.8 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MCM PF00493.18 EMC90066.1 - 3.2e-135 450.2 0.1 4.3e-135 449.7 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMC90066.1 - 1.1e-16 61.3 0.1 3.5e-16 59.7 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMC90066.1 - 9.7e-07 28.1 0.0 0.00043 19.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMC90066.1 - 0.00046 19.9 0.0 0.0015 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMC90066.1 - 0.006 16.1 0.0 0.02 14.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMC90066.1 - 0.022 14.2 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TrmB PF01978.14 EMC90066.1 - 0.097 12.3 1.3 0.46 10.2 0.3 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB SWIB PF02201.13 EMC90067.1 - 1.2e-19 69.8 0.2 2.5e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C3HC4_3 PF13920.1 EMC90067.1 - 2.8e-11 42.8 9.7 2.8e-11 42.8 6.7 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 EMC90067.1 - 5.4e-09 34.9 1.9 5.4e-09 34.9 1.3 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 EMC90067.1 - 2.6e-06 27.3 10.7 2.6e-06 27.3 7.4 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EMC90067.1 - 0.057 13.2 12.9 0.75 9.6 0.7 3.0 2 0 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 EMC90067.1 - 0.17 11.5 0.1 0.17 11.5 0.1 3.6 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-RING_2 PF13639.1 EMC90067.1 - 0.67 9.8 14.1 0.05 13.4 6.1 2.0 2 0 0 2 2 2 0 Ring finger domain Zip PF02535.17 EMC90067.1 - 2 7.3 4.9 0.36 9.7 0.2 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Peptidase_M14 PF00246.19 EMC90068.1 - 7.9e-69 232.3 0.1 9.6e-69 232.0 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 EMC90068.1 - 2e-11 43.8 0.0 6.6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMC90068.1 - 7.9e-09 35.4 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 EMC90068.1 - 4.3e-07 29.0 0.1 7.5e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Dioxygenase_C PF00775.16 EMC90068.1 - 0.0092 15.2 0.1 0.027 13.7 0.0 1.8 2 0 0 2 2 2 1 Dioxygenase TPR_11 PF13414.1 EMC90069.1 - 2.6e-09 36.5 5.3 0.00018 21.0 1.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC90069.1 - 7.1e-08 31.7 3.5 0.00014 21.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC90069.1 - 0.00048 20.7 1.8 0.39 11.4 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat PaREP1 PF05942.6 EMC90069.1 - 0.047 13.5 0.8 0.077 12.8 0.4 1.7 1 1 0 1 1 1 0 Archaeal PaREP1/PaREP8 family TPR_1 PF00515.23 EMC90069.1 - 0.14 11.7 9.7 0.41 10.3 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat NDUFB10 PF10249.4 EMC90069.1 - 0.15 12.1 1.9 0.22 11.6 1.3 1.4 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 TPR_12 PF13424.1 EMC90069.1 - 0.18 11.7 1.8 8.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMC90069.1 - 0.89 9.7 8.9 2.1 8.5 2.0 2.8 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMC90069.1 - 1.4 9.5 3.8 13 6.4 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat EF-hand_1 PF00036.27 EMC90070.1 - 1.4e-32 108.4 12.8 5.6e-10 37.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EMC90070.1 - 1.1e-25 87.1 6.0 3.8e-09 35.6 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EMC90070.1 - 2.1e-25 88.6 8.6 1.2e-16 60.6 1.2 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC90070.1 - 9.3e-24 82.8 10.8 1.8e-13 49.8 1.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC90070.1 - 1.1e-23 81.4 10.5 3.2e-09 35.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EMC90070.1 - 4.7e-09 36.0 0.2 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EMC90070.1 - 0.0001 22.2 0.0 0.0096 15.9 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC90070.1 - 0.0011 18.7 2.5 0.037 13.7 0.2 2.7 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Prefoldin_3 PF13758.1 EMC90070.1 - 0.0094 15.7 0.0 0.57 9.9 0.0 2.3 1 1 1 2 2 2 1 Prefoldin subunit TerB PF05099.8 EMC90070.1 - 0.063 13.0 0.3 5.8 6.6 0.0 2.6 2 1 0 3 3 3 0 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.5 EMC90070.1 - 0.073 13.0 2.7 0.57 10.1 0.4 2.9 2 2 0 2 2 2 0 Ca2+ insensitive EF hand FliG_N PF14842.1 EMC90070.1 - 0.08 13.0 0.7 1 9.5 0.1 2.3 2 0 0 2 2 2 0 FliG N-terminal domain Lip_prot_lig_C PF10437.4 EMC90070.1 - 0.087 12.5 0.3 1 9.0 0.0 2.6 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus Dockerin_1 PF00404.13 EMC90070.1 - 0.54 10.0 5.6 7.1 6.5 0.1 3.0 3 0 0 3 3 3 0 Dockerin type I repeat Mito_carr PF00153.22 EMC90071.1 - 4e-15 55.2 0.0 3.6e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein WW PF00397.21 EMC90072.1 - 4.8e-15 55.1 17.7 1.8e-07 30.8 4.3 2.6 2 0 0 2 2 2 2 WW domain RhoGEF PF00621.15 EMC90073.1 - 1.4e-44 152.1 0.1 1.6e-44 151.9 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain Prenyltrans PF00432.16 EMC90074.1 - 1.9e-29 100.9 20.3 1.3e-11 43.8 0.4 3.8 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMC90074.1 - 1.2e-08 35.3 0.1 5.3e-06 26.8 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like Churchill PF06573.6 EMC90074.1 - 1.7e-08 34.4 0.8 1.7e-08 34.4 0.5 2.0 2 0 0 2 2 2 1 Churchill protein HLH PF00010.21 EMC90075.1 - 2.5e-19 68.6 0.7 4.5e-19 67.8 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 EMC90075.1 - 0.00024 20.7 3.6 0.00029 20.4 2.5 1.1 1 0 0 1 1 1 1 IncA protein Myosin_tail_1 PF01576.14 EMC90075.1 - 0.0048 14.7 5.2 0.0052 14.5 3.6 1.0 1 0 0 1 1 1 1 Myosin tail bZIP_2 PF07716.10 EMC90075.1 - 0.0059 16.4 5.9 0.01 15.6 2.7 2.3 2 1 0 2 2 2 1 Basic region leucine zipper CENP-Q PF13094.1 EMC90075.1 - 0.0073 16.3 3.4 0.013 15.5 2.3 1.5 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4618 PF15397.1 EMC90075.1 - 0.014 14.7 2.7 0.1 11.9 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Filament PF00038.16 EMC90075.1 - 0.014 14.8 5.7 0.016 14.7 4.0 1.0 1 0 0 1 1 1 0 Intermediate filament protein Ax_dynein_light PF10211.4 EMC90075.1 - 0.018 14.8 3.8 0.021 14.6 2.6 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain SlyX PF04102.7 EMC90075.1 - 0.032 14.6 3.9 0.054 13.8 1.8 2.0 1 1 1 2 2 2 0 SlyX TPR_MLP1_2 PF07926.7 EMC90075.1 - 0.041 13.6 3.1 0.058 13.1 2.1 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CAGE1 PF15066.1 EMC90075.1 - 0.043 12.2 0.7 0.041 12.3 0.5 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family GAS PF13851.1 EMC90075.1 - 0.044 12.9 3.8 0.05 12.8 2.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 EMC90075.1 - 0.06 13.0 3.8 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper ATG16 PF08614.6 EMC90075.1 - 0.069 12.9 6.2 0.082 12.7 4.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EMC90075.1 - 0.076 12.8 3.5 0.077 12.8 1.7 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding LepA_C PF06421.7 EMC90075.1 - 0.1 12.4 1.2 0.11 12.3 0.8 1.1 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus Tropomyosin_1 PF12718.2 EMC90075.1 - 0.11 12.3 3.3 0.048 13.4 0.8 1.5 2 0 0 2 2 2 0 Tropomyosin like PMBR PF09373.5 EMC90075.1 - 0.12 12.3 0.1 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein-binding repeat POLO_box PF00659.13 EMC90075.1 - 0.16 11.9 0.6 0.35 10.8 0.1 1.7 2 0 0 2 2 2 0 POLO box duplicated region Fib_alpha PF08702.5 EMC90075.1 - 0.2 11.7 2.9 0.21 11.6 2.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SLX9 PF15341.1 EMC90075.1 - 0.34 11.3 3.6 0.4 11.1 2.5 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DivIC PF04977.10 EMC90075.1 - 0.36 10.3 5.2 0.3 10.6 2.4 1.7 1 1 1 2 2 2 0 Septum formation initiator Uds1 PF15456.1 EMC90075.1 - 0.4 10.6 5.4 2 8.4 2.8 2.0 1 1 1 2 2 2 0 Up-regulated During Septation DOR PF14839.1 EMC90075.1 - 2.2 8.0 6.4 2.4 7.8 4.5 1.2 1 0 0 1 1 1 0 DOR family Atg14 PF10186.4 EMC90075.1 - 4.9 6.0 7.6 5.7 5.7 5.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UNC-93 PF05978.11 EMC90076.1 - 2.1e-05 24.0 4.0 2.1e-05 24.0 2.7 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Aldedh PF00171.17 EMC90077.1 - 2.2e-88 296.6 0.0 2.8e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMC90077.1 - 0.00011 21.1 0.0 0.00013 20.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Fer4 PF00037.22 EMC90078.1 - 8e-15 53.7 17.3 1.2e-08 34.1 3.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EMC90078.1 - 2.2e-12 47.1 11.3 3.6e-12 46.4 7.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMC90078.1 - 2.2e-11 44.3 6.8 5.8e-05 23.7 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EMC90078.1 - 1.3e-10 40.9 3.8 3.2e-05 23.6 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMC90078.1 - 3.4e-10 39.5 22.5 2.4e-08 33.6 8.8 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMC90078.1 - 4.9e-10 39.2 29.5 6.2e-06 26.1 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMC90078.1 - 5.6e-10 39.3 11.2 1.1e-09 38.4 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMC90078.1 - 4.9e-09 35.5 15.4 6.9e-05 22.5 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EMC90078.1 - 1.7e-08 33.9 17.9 0.00042 20.0 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EMC90078.1 - 1e-06 28.5 12.4 0.00046 20.2 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EMC90078.1 - 3.7e-06 27.2 9.5 0.002 18.4 0.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EMC90078.1 - 5.9e-06 26.5 10.2 0.00029 21.1 8.0 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.1 EMC90078.1 - 0.0013 19.0 14.5 0.14 12.5 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EMC90078.1 - 0.0045 17.5 12.8 0.34 11.5 1.2 3.0 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EMC90078.1 - 0.011 16.1 18.9 0.058 13.9 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EMC90078.1 - 0.23 11.5 5.5 0.8 9.8 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Prenyltrans PF00432.16 EMC90079.1 - 3.5 7.2 11.2 2.3 7.8 1.2 3.2 2 1 1 3 3 3 0 Prenyltransferase and squalene oxidase repeat V_ATPase_I PF01496.14 EMC90080.1 - 2.1e-229 763.2 0.4 2.4e-229 763.1 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family T-box PF00907.17 EMC90081.1 - 3.8e-70 235.1 0.7 2.1e-67 226.1 0.5 2.0 1 1 0 1 1 1 1 T-box ABC_transp_aux PF09822.4 EMC90081.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system 7tm_4 PF13853.1 EMC90082.1 - 1.7e-35 121.8 10.4 1.7e-35 121.8 7.2 2.0 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 EMC90082.1 - 8.8e-33 113.5 13.9 1.3e-32 112.9 9.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90082.1 - 0.002 17.3 14.1 0.0056 15.8 9.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 EMC90083.1 - 5.9e-43 146.1 10.7 5.9e-43 146.1 7.4 2.4 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC90083.1 - 9.4e-28 97.0 17.4 1.3e-27 96.6 12.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF420 PF04238.7 EMC90083.1 - 1.1 9.1 10.3 0.77 9.7 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF420) 7tm_4 PF13853.1 EMC90084.1 - 2.6e-50 169.9 8.4 2.6e-50 169.9 5.8 2.7 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 EMC90084.1 - 1.4e-25 89.9 16.9 2.1e-25 89.3 11.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90084.1 - 0.00057 19.1 14.8 0.0014 17.8 10.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SP_C-Propep PF08999.5 EMC90084.1 - 0.16 11.4 5.4 0.79 9.2 0.0 2.8 2 1 1 3 3 3 0 Surfactant protein C, N terminal propeptide 7tm_1 PF00001.16 EMC90085.1 - 7.3e-45 153.1 16.3 4.6e-24 84.9 5.7 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90085.1 - 1.1e-11 44.3 16.2 4.4e-06 26.0 4.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx XPG_N PF00752.12 EMC90086.1 - 4.2e-37 126.4 0.0 1.4e-36 124.7 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EMC90086.1 - 2.8e-30 104.2 0.0 6.6e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EMC90086.1 - 8e-08 32.4 0.1 3.5e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 EMC90086.1 - 0.056 13.6 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain UPF0197 PF05251.7 EMC90087.1 - 1.6e-35 121.2 8.8 1.8e-35 121.0 6.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Polysacc_synt_C PF14667.1 EMC90087.1 - 0.035 13.9 4.9 0.04 13.7 3.4 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.1 EMC90087.1 - 0.98 8.8 5.8 1.1 8.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) zf-DHHC PF01529.15 EMC90087.1 - 4.2 6.7 5.9 4.2 6.7 4.1 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase CAAD PF14159.1 EMC90087.1 - 8.2 6.1 6.6 0.91 9.2 0.4 1.9 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Sdh5 PF03937.11 EMC90088.1 - 2.3e-22 78.4 0.7 3.2e-22 78.0 0.5 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Transmemb_17 PF09799.4 EMC90089.1 - 2.4e-15 56.7 4.7 3e-15 56.4 3.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein Lactamase_B_4 PF13691.1 EMC90089.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 tRNase Z endonuclease TMEM138 PF14935.1 EMC90090.1 - 7.2e-33 113.4 9.8 1.2e-32 112.7 6.8 1.3 1 0 0 1 1 1 1 Transmembrane protein 138 Cytochrom_B561 PF03188.11 EMC90091.1 - 4.2e-45 152.9 7.8 4.2e-45 152.9 5.4 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM_3 PF13706.1 EMC90091.1 - 0.0044 16.3 1.6 0.0044 16.3 1.1 3.6 4 0 0 4 4 4 1 PepSY-associated TM helix Ni_hydr_CYTB PF01292.15 EMC90091.1 - 0.68 9.3 23.7 22 4.3 14.9 2.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4079 PF13301.1 EMC90091.1 - 0.69 9.9 13.8 0.11 12.4 4.4 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF4079) Dak1 PF02733.12 EMC90092.1 - 2.1e-44 151.4 0.0 3e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMC90092.1 - 1.2e-31 109.7 0.0 1.9e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 DAK2 domain DUF3846 PF12957.2 EMC90092.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) MMS1_N PF10433.4 EMC90093.1 - 2.4e-94 316.2 0.0 8.3e-94 314.5 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EMC90093.1 - 1.4e-83 280.7 0.1 1.5e-82 277.2 0.0 2.6 2 0 0 2 2 2 1 CPSF A subunit region Beta_propel PF09826.4 EMC90093.1 - 0.017 13.5 0.0 0.027 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta propeller domain VWC PF00093.13 EMC90094.1 - 4.5e-22 77.9 90.1 4.6e-09 36.2 7.3 6.5 6 1 0 6 6 6 5 von Willebrand factor type C domain Asp PF00026.18 EMC90095.1 - 1.1e-111 373.1 0.3 1.2e-111 372.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMC90095.1 - 4.8e-14 52.6 0.9 6.3e-13 49.0 0.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMC90095.1 - 8.2e-07 29.4 0.0 0.0079 16.6 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMC90095.1 - 7.8e-06 25.5 0.0 0.0057 16.2 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor C-terminal AvrRpt-cleavage PF05627.6 EMC90095.1 - 0.083 11.9 0.6 1.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr Methyltransf_32 PF13679.1 EMC90096.1 - 1.1e-28 99.7 8.1 2.3e-27 95.4 5.6 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMC90096.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMC90096.1 - 0.00019 21.1 0.0 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMC90096.1 - 0.00032 21.2 0.0 0.00079 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC90096.1 - 0.0035 17.7 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC90096.1 - 0.02 15.3 0.0 0.052 14.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EMC90096.1 - 0.053 12.8 0.0 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 EMC90096.1 - 0.061 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EMC90096.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NapE PF06796.6 EMC90096.1 - 0.095 12.0 0.2 0.36 10.1 0.0 2.1 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE Collagen PF01391.13 EMC90097.1 - 4.8e-13 48.4 82.1 9.4e-09 34.6 25.4 3.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MIP-T3 PF10243.4 EMC90097.1 - 2.3 6.5 43.2 3.4 6.0 30.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 EMC90097.1 - 7.2 4.3 27.6 9.2 4.0 19.1 1.0 1 0 0 1 1 1 0 Nop14-like family NUDIX PF00293.23 EMC90098.1 - 3.1e-16 59.2 0.0 8.8e-16 57.7 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Ank_2 PF12796.2 EMC90098.1 - 6.6e-11 42.3 0.9 2e-10 40.8 0.5 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC90098.1 - 8.1e-10 38.9 3.9 3e-05 24.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC90098.1 - 1.4e-09 37.8 0.2 3.4e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EMC90098.1 - 7.6e-09 34.9 1.1 7.3e-07 28.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat zf-NADH-PPase PF09297.6 EMC90098.1 - 3.5e-08 32.8 0.6 6.1e-08 32.0 0.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 EMC90098.1 - 1.4e-07 31.7 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank_3 PF13606.1 EMC90098.1 - 1.4e-06 27.9 0.4 1.9e-05 24.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PH PF00169.24 EMC90099.1 - 5.2e-25 87.6 0.7 7.8e-15 54.9 0.1 2.6 3 0 0 3 3 3 2 PH domain PDZ PF00595.19 EMC90099.1 - 2e-14 53.4 0.1 3.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH_11 PF15413.1 EMC90099.1 - 8.5e-11 42.0 9.9 1.5e-06 28.4 3.0 4.2 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 EMC90099.1 - 8.3e-08 32.1 0.6 1.8e-06 27.9 0.3 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.1 EMC90099.1 - 4.8e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.1 EMC90099.1 - 0.0035 17.4 1.0 0.95 9.6 0.1 3.4 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EMC90099.1 - 0.007 16.2 0.3 0.088 12.7 0.0 2.3 2 0 0 2 2 2 1 PH domain UNC119_bdg PF15435.1 EMC90100.1 - 5e-109 362.1 0.8 5.7e-109 361.9 0.5 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue His_Phos_2 PF00328.17 EMC90101.1 - 2e-109 366.1 1.0 2.6e-109 365.7 0.7 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EMC90101.1 - 0.00012 21.5 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 EMC90101.1 - 0.017 15.2 0.1 0.082 12.9 0.0 2.2 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) rve PF00665.21 EMC90102.1 - 3.3e-07 30.4 0.0 2.6e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EMC90102.1 - 5.8e-05 22.4 2.6 0.00015 21.1 1.8 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Pox_A3L PF05288.6 EMC90102.1 - 0.025 14.2 0.1 0.09 12.5 0.1 1.9 1 0 0 1 1 1 0 Poxvirus A3L Protein Cu2_monoox_C PF03712.10 EMC90103.1 - 4.5e-50 169.0 0.6 1e-49 167.9 0.4 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.15 EMC90103.1 - 4.1e-32 110.9 0.0 8.6e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.16 EMC90103.1 - 6.9e-26 88.8 6.2 3.8e-07 29.7 0.0 6.1 6 0 0 6 6 6 4 NHL repeat DUF2208 PF09973.4 EMC90103.1 - 0.061 12.5 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) OATP PF03137.15 EMC90104.1 - 9.4e-30 103.1 1.5 1.2e-29 102.7 1.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EMC90104.1 - 0.016 13.9 4.5 0.024 13.3 3.1 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily CRAL_TRIO PF00650.15 EMC90104.1 - 0.02 14.3 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain Claudin_3 PF06653.6 EMC90104.1 - 0.5 10.0 6.5 1.2 8.8 4.5 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Clc-like PF07062.7 EMC90104.1 - 2.8 7.1 6.1 4.5 6.4 4.2 1.3 1 1 0 1 1 1 0 Clc-like TLV_coat PF00429.14 EMC90105.1 - 2.5e-11 42.7 1.4 2.8e-11 42.5 1.0 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC90105.1 - 0.0033 17.0 0.1 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral envelope protein CorA PF01544.13 EMC90105.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2239 PF09998.4 EMC90105.1 - 1.6 8.2 3.9 8.5 5.9 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Glyco_transf_29 PF00777.13 EMC90107.1 - 5.8e-76 255.1 0.0 7.3e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RVT_1 PF00078.22 EMC90108.1 - 0.027 13.8 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PurA PF04845.8 EMC90110.1 - 4.6e-106 352.8 0.0 5.4e-106 352.6 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.3 EMC90110.1 - 1.5e-06 28.0 0.2 0.39 10.5 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3276) Metallophos PF00149.23 EMC90112.1 - 4.9e-42 143.6 0.8 6.4e-42 143.2 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YqzH PF14164.1 EMC90112.1 - 1.1 9.2 3.3 1.2 9.0 0.7 2.1 2 0 0 2 2 2 0 YqzH-like protein Pyr_redox PF00070.22 EMC90113.1 - 6.6e-19 68.0 0.1 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMC90113.1 - 2.1e-15 57.1 0.0 1.2e-14 54.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMC90113.1 - 1.1e-14 54.3 0.1 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 EMC90113.1 - 5.8e-05 23.2 0.0 0.019 15.0 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMC90113.1 - 0.00025 20.0 0.0 0.00072 18.5 0.0 1.6 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Tom5 PF10642.4 EMC90114.1 - 0.072 12.7 0.6 18 5.1 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial import receptor subunit or translocase DUF4091 PF13320.1 EMC90114.1 - 0.28 11.0 6.6 15 5.6 0.1 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF4091) Thia_YuaJ PF09515.5 EMC90114.1 - 1.4 8.6 11.3 0.82 9.4 0.6 2.9 1 1 1 3 3 3 0 Thiamine transporter protein (Thia_YuaJ) SPRY PF00622.23 EMC90115.1 - 2.4e-24 85.7 0.1 3.2e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 EMC90115.1 - 1.3e-20 72.6 0.1 2.2e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain MBT PF02820.13 EMC90116.1 - 3.2e-48 161.5 0.1 2.7e-24 84.8 0.0 2.5 2 0 0 2 2 2 2 mbt repeat DUF3588 PF12140.3 EMC90116.1 - 2.8e-43 146.7 0.2 5e-43 145.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 EMC90116.1 - 3.5e-08 33.5 0.0 6.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMC90116.1 - 2e-05 24.2 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 EMC90116.1 - 0.00018 21.3 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 EMC90116.1 - 0.0024 17.8 2.0 0.0064 16.5 0.1 2.5 2 1 1 3 3 3 1 Ste50p, sterile alpha motif DUF843 PF05814.6 EMC90117.1 - 0.0019 17.9 0.2 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF843) Pescadillo_N PF06732.6 EMC90117.1 - 0.0098 15.1 0.3 0.011 14.9 0.2 1.0 1 0 0 1 1 1 1 Pescadillo N-terminus DUF2140 PF09911.4 EMC90117.1 - 0.028 13.5 0.1 0.03 13.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) FAM209 PF15206.1 EMC90117.1 - 0.03 14.1 0.0 0.032 14.0 0.0 1.0 1 0 0 1 1 1 0 FAM209 family 7TM_GPCR_Srd PF10317.4 EMC90117.1 - 0.051 12.5 0.1 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd OAD_gamma PF04277.8 EMC90117.1 - 0.062 13.6 0.2 0.062 13.6 0.1 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3278 PF11683.3 EMC90117.1 - 0.083 12.8 0.1 0.099 12.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF1632 PF07857.7 EMC90117.1 - 0.1 11.8 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 CEO family (DUF1632) MFS_1 PF07690.11 EMC90117.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Col_cuticle_N PF01484.12 EMC90117.1 - 0.1 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain PDR_CDR PF06422.7 EMC90117.1 - 0.12 12.1 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 CDR ABC transporter TMEM192 PF14802.1 EMC90118.1 - 1.2e-79 266.5 2.6 1.3e-79 266.3 1.8 1.0 1 0 0 1 1 1 1 TMEM192 family Fig1 PF12351.3 EMC90118.1 - 0.03 14.2 1.0 0.04 13.7 0.3 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 NfeD PF01957.13 EMC90118.1 - 0.1 12.7 0.1 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Kelch_1 PF01344.20 EMC90119.1 - 7.8e-82 268.6 18.4 4.8e-15 54.8 0.5 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EMC90119.1 - 5.8e-43 143.3 3.6 9.1e-08 31.9 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EMC90119.1 - 1.3e-33 114.3 13.2 2.2e-06 27.6 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC90119.1 - 1.1e-31 107.3 10.2 1.5e-05 24.5 0.1 6.3 6 0 0 6 6 6 5 Kelch motif BTB PF00651.26 EMC90119.1 - 1.6e-31 108.5 0.1 3.4e-31 107.4 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EMC90119.1 - 1.4e-30 105.1 1.5 5.3e-30 103.3 1.0 2.0 1 1 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 EMC90119.1 - 3.1e-28 97.2 7.2 6.6e-05 22.6 0.1 6.3 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC90119.1 - 1.1e-07 31.6 16.6 0.3 11.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.1 EMC90119.1 - 0.0031 17.7 10.2 1.5 9.1 0.0 4.9 5 0 0 5 5 5 1 PQQ-like domain Ashwin PF15323.1 EMC90119.1 - 0.1 12.5 0.4 0.17 11.8 0.3 1.2 1 0 0 1 1 1 0 Developmental protein FA_hydroxylase PF04116.8 EMC90120.1 - 1.2e-14 54.6 17.2 1.2e-14 54.6 11.9 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M14 PF00246.19 EMC90121.1 - 8.1e-63 212.6 0.0 9.7e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 EMC90121.1 - 1.4e-15 57.0 0.0 2.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMC90121.1 - 2.5e-07 30.6 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 EMC90121.1 - 0.049 12.4 0.1 0.13 11.1 0.0 1.6 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 EMC90121.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) CUB PF00431.15 EMC90122.1 - 6.6e-187 608.7 6.7 2.6e-40 136.8 0.2 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.19 EMC90122.1 - 4e-73 244.8 0.1 9.3e-73 243.6 0.0 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.1 EMC90122.1 - 1.1e-19 70.2 28.3 1.1e-09 38.2 6.7 2.9 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 EMC90122.1 - 2.3e-12 46.6 30.7 3.6e-07 30.0 5.9 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.2 EMC90122.1 - 5.2e-09 35.5 6.7 6.2e-05 22.5 0.9 3.3 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.2 EMC90122.1 - 3.3e-05 23.7 24.3 0.00058 19.7 3.5 3.4 2 1 1 3 3 3 2 EGF domain CUB_2 PF02408.15 EMC90122.1 - 6.6e-05 22.4 5.8 0.71 9.4 0.1 4.4 4 0 0 4 4 4 3 CUB-like domain Peptidase_M10 PF00413.19 EMC90122.1 - 0.003 17.3 0.1 0.55 9.9 0.1 2.6 2 0 0 2 2 2 1 Matrixin Reprolysin_2 PF13574.1 EMC90122.1 - 0.0057 16.7 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC90122.1 - 0.018 14.5 0.1 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SPARC_Ca_bdg PF10591.4 EMC90123.1 - 2.1e-32 111.5 1.9 3.5e-32 110.7 1.3 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.13 EMC90123.1 - 1.5e-15 56.2 7.1 1.5e-15 56.2 4.9 3.3 4 0 0 4 4 4 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.10 EMC90123.1 - 1.2e-10 41.1 7.0 1.2e-10 41.1 4.8 3.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EMC90123.1 - 1.2e-08 34.7 9.0 1.2e-08 34.7 6.2 3.9 4 1 0 4 4 4 1 Kazal-type serine protease inhibitor domain CDC45 PF02724.9 EMC90123.1 - 2 6.3 6.6 2.5 6.0 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein C1-set PF07654.10 EMC90124.1 - 5.5e-13 48.7 0.4 1.1e-12 47.7 0.1 1.6 2 0 0 2 2 2 1 Immunoglobulin C1-set domain V-set PF07686.12 EMC90124.1 - 5.2e-12 45.6 1.0 1e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC90124.1 - 0.0001 22.3 0.3 0.44 10.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC90124.1 - 0.016 15.3 0.2 0.071 13.2 0.0 2.3 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.11 EMC90124.1 - 0.04 13.7 0.5 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin I-set domain Uroplakin_II PF07353.7 EMC90124.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Uroplakin II Ig_3 PF13927.1 EMC90124.1 - 0.61 10.6 2.7 5.7 7.5 0.1 2.9 1 1 2 3 3 3 0 Immunoglobulin domain Reo_sigmaC PF04582.7 EMC90125.1 - 0.11 11.6 2.5 0.056 12.6 0.2 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Cation_ATPase_N PF00690.21 EMC90126.1 - 4.5e-14 51.6 0.0 8.5e-14 50.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF4149 PF13664.1 EMC90126.1 - 0.0084 16.1 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) Tetraspannin PF00335.15 EMC90126.1 - 0.034 13.4 1.0 0.039 13.2 0.7 1.1 1 0 0 1 1 1 0 Tetraspanin family BCCT PF02028.12 EMC90126.1 - 0.044 12.0 0.0 0.05 11.8 0.0 1.0 1 0 0 1 1 1 0 BCCT family transporter ABC2_membrane_4 PF12730.2 EMC90126.1 - 0.045 12.8 0.2 0.056 12.6 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Bax1-I PF01027.15 EMC90126.1 - 0.074 12.6 0.0 0.088 12.3 0.0 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 E1-E2_ATPase PF00122.15 EMC90126.1 - 0.078 12.0 0.3 0.11 11.5 0.0 1.4 2 0 0 2 2 2 0 E1-E2 ATPase Cation_efflux PF01545.16 EMC90126.1 - 0.11 11.5 0.1 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Cation efflux family DUF872 PF05915.7 EMC90126.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) PepSY_TM_3 PF13706.1 EMC90126.1 - 0.93 8.9 4.9 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 PepSY-associated TM helix PRY PF13765.1 EMC90127.1 - 4.8e-20 70.8 0.4 7.5e-20 70.2 0.3 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 EMC90127.1 - 2e-19 69.8 1.0 2.6e-19 69.5 0.7 1.1 1 0 0 1 1 1 1 SPRY domain LRR_8 PF13855.1 EMC90128.1 - 9.5e-31 105.3 23.0 4.6e-15 55.1 1.9 3.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EMC90128.1 - 3.4e-22 77.5 13.5 1.4e-07 30.9 2.8 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC90128.1 - 1e-17 61.4 10.3 0.0062 16.4 0.0 6.9 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 EMC90128.1 - 8e-14 49.3 20.0 0.037 14.1 0.1 7.3 7 0 0 7 7 7 5 Leucine rich repeat LRR_6 PF13516.1 EMC90128.1 - 1.8e-10 39.7 7.6 0.72 10.1 0.1 5.8 5 0 0 5 5 5 5 Leucine Rich repeat LRR_9 PF14580.1 EMC90128.1 - 2.7e-07 30.3 0.8 0.0055 16.2 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.1 EMC90128.1 - 0.0022 17.6 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRRNT PF01462.13 EMC90128.1 - 0.049 13.1 0.5 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Kelch_1 PF01344.20 EMC90129.1 - 2.5e-37 126.1 11.7 7.1e-12 44.6 0.1 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EMC90129.1 - 1.9e-31 106.9 6.8 2e-09 37.2 0.1 5.8 4 2 2 6 6 6 4 Kelch motif BACK PF07707.10 EMC90129.1 - 1.4e-20 73.0 0.0 2.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 EMC90129.1 - 8.6e-20 70.3 9.4 5.3e-05 23.2 0.2 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EMC90129.1 - 3.5e-16 58.6 10.0 0.00053 19.7 0.1 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC90129.1 - 2.2e-14 52.5 6.3 0.03 14.0 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMC90129.1 - 2.1e-10 40.2 17.3 0.00034 20.4 0.5 5.4 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EMC90129.1 - 0.05 13.5 0.0 0.18 11.8 0.0 1.9 1 1 1 2 2 2 0 BTB/POZ domain Tim17 PF02466.14 EMC90130.1 - 8.1e-13 48.5 0.9 1.3e-12 47.8 0.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ran_BP1 PF00638.13 EMC90132.1 - 6.5e-14 52.0 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain FAM101 PF15068.1 EMC90132.1 - 0.066 12.6 0.3 0.066 12.6 0.2 2.9 1 1 3 4 4 4 0 FAM101 family ACOX PF01756.14 EMC90132.1 - 0.51 9.6 3.5 0.15 11.3 0.3 1.6 2 0 0 2 2 2 0 Acyl-CoA oxidase Vanabin-2 PF11437.3 EMC90133.1 - 1.3 9.0 16.3 3.5 7.6 0.3 3.7 2 1 1 3 3 3 0 Vanadium-binding protein 2 I-set PF07679.11 EMC90135.1 - 8.1e-70 230.7 0.9 6.3e-17 61.2 0.0 6.6 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90135.1 - 1.1e-49 166.4 0.1 5.7e-10 39.1 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.16 EMC90135.1 - 8.3e-46 154.0 21.5 9.5e-16 57.7 1.8 4.4 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.12 EMC90135.1 - 8.8e-34 115.8 2.7 1.4e-06 28.1 0.0 8.1 7 1 0 7 7 7 5 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC90135.1 - 5.2e-30 103.7 3.8 1.5e-07 31.7 0.0 7.7 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.20 EMC90135.1 - 1.2e-28 99.0 10.3 3.6e-07 30.2 0.0 8.4 8 2 0 8 8 8 5 Immunoglobulin domain Tissue_fac PF01108.12 EMC90135.1 - 7.5e-09 35.2 6.3 5.3e-06 26.1 0.4 3.3 3 1 1 4 4 4 2 Tissue factor Sp38 PF07354.7 EMC90135.1 - 7.9e-05 21.4 0.1 1.3 7.6 0.0 4.1 5 0 0 5 5 5 2 Zona-pellucida-binding protein (Sp38) C2-set_2 PF08205.7 EMC90135.1 - 0.00023 21.0 8.9 0.83 9.6 0.0 5.4 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 EMC90135.1 - 0.0034 17.3 0.2 4.8 7.2 0.0 3.3 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III zf-C3HC4 PF00097.20 EMC90136.1 - 4.4e-08 32.6 6.2 1.7e-07 30.7 4.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PDZ PF00595.19 EMC90136.1 - 5.2e-08 32.9 0.1 1.3e-07 31.7 0.2 1.5 2 0 0 2 2 1 1 PDZ domain (Also known as DHR or GLGF) zf-C3HC4_2 PF13923.1 EMC90136.1 - 7.2e-08 32.3 8.0 2.5e-07 30.5 5.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMC90136.1 - 1.9e-07 30.7 8.0 1.9e-07 30.7 5.6 2.4 3 0 0 3 3 2 1 Ring finger domain Sina PF03145.11 EMC90136.1 - 9.7e-07 28.6 2.9 1.6e-06 27.9 2.0 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_5 PF14634.1 EMC90136.1 - 1e-06 28.3 6.6 1e-06 28.3 4.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMC90136.1 - 2.3e-06 27.1 5.3 8.4e-06 25.3 3.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMC90136.1 - 1.3e-05 25.0 7.8 3.7e-05 23.5 5.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.13 EMC90136.1 - 8.6e-05 22.8 11.9 0.00064 20.0 3.1 2.9 1 1 1 2 2 2 2 TRAF-type zinc finger zf-RING_6 PF14835.1 EMC90136.1 - 0.0016 18.2 2.5 0.0044 16.7 1.7 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 EMC90136.1 - 0.0053 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 EMC90136.1 - 0.014 15.4 2.9 0.053 13.6 2.0 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EMC90136.1 - 0.04 13.4 4.0 0.15 11.6 2.8 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EMC90136.1 - 0.097 12.4 6.1 0.29 10.9 4.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PDZ_2 PF13180.1 EMC90136.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PPP4R2 PF09184.6 EMC90137.1 - 5.7e-89 298.4 0.5 5.7e-89 298.4 0.3 2.8 1 1 0 2 2 2 1 PPP4R2 Glyco_transf_8 PF01501.15 EMC90138.1 - 1.1e-15 57.6 0.1 2.4e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 zf-RanBP PF00641.13 EMC90139.1 - 1.5e-08 33.5 2.4 3e-08 32.6 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MIP-T3 PF10243.4 EMC90139.1 - 5.7 5.2 27.9 7.2 4.9 19.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Prokineticin PF06607.6 EMC90140.1 - 7.5e-40 134.9 9.5 8.3e-40 134.8 6.6 1.0 1 0 0 1 1 1 1 Prokineticin 7tm_1 PF00001.16 EMC90141.1 - 1.4e-33 116.0 11.4 2e-33 115.6 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 EMC90142.1 - 1.9e-10 40.3 0.1 2.4e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V-set PF07686.12 EMC90143.1 - 5.5e-15 55.2 0.2 5.7e-15 55.1 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC90143.1 - 6e-05 22.8 0.2 0.00015 21.5 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC90143.1 - 0.00013 22.4 0.5 0.00036 20.9 0.3 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC90143.1 - 0.00024 21.1 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC90143.1 - 0.042 13.9 0.6 3.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain V-set PF07686.12 EMC90144.1 - 1.8e-15 56.8 0.0 1.9e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC90144.1 - 3.7e-07 30.1 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC90144.1 - 9.6e-06 26.0 0.1 1.5e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC90144.1 - 4.1e-05 23.3 0.0 0.0001 22.0 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 EMC90144.1 - 5.8e-05 23.1 0.1 0.033 14.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Apelin PF15360.1 EMC90145.1 - 0.32 11.2 0.2 0.32 11.2 0.1 2.3 2 0 0 2 2 2 0 APJ endogenous ligand Choline_transpo PF04515.7 EMC90147.1 - 4.9e-113 377.2 33.4 4.9e-113 377.2 23.1 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter C2 PF00168.25 EMC90149.1 - 3.9e-67 222.1 7.3 3.8e-15 55.5 0.0 9.2 9 0 0 9 9 9 6 C2 domain FerB PF08150.7 EMC90149.1 - 1.9e-37 127.2 0.3 5.9e-37 125.6 0.1 2.0 2 0 0 2 2 2 1 FerB (NUC096) domain FerI PF08151.7 EMC90149.1 - 1.5e-13 50.5 0.8 1.4e-08 34.6 0.0 2.8 1 1 1 2 2 2 2 FerI (NUC094) domain DUF3317 PF11779.3 EMC90149.1 - 0.24 10.8 2.7 31 4.1 1.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) Myotub-related PF06602.9 EMC90152.1 - 5.9e-144 479.2 0.0 7.8e-144 478.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.16 EMC90152.1 - 2.2e-16 59.5 13.4 7.2e-16 57.8 9.3 2.0 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase PF00102.22 EMC90152.1 - 0.0027 17.0 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMC90152.1 - 0.011 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC90152.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_C14 PF00656.17 EMC90153.1 - 7.1e-41 140.5 0.0 9.1e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.16 EMC90153.1 - 4.7e-16 58.3 0.9 1.9e-15 56.4 0.2 2.1 2 0 0 2 2 2 1 Caspase recruitment domain DUF1338 PF07063.8 EMC90153.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) Abhydrolase_6 PF12697.2 EMC90154.1 - 9.4e-27 94.3 0.0 1.1e-26 94.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC90154.1 - 4.7e-20 72.1 0.0 3.1e-18 66.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMC90154.1 - 1.1e-10 41.4 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMC90154.1 - 2.7e-07 30.4 0.1 3.6e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF2048 PF09752.4 EMC90154.1 - 0.0002 20.3 0.0 0.001 18.0 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 EMC90154.1 - 0.00031 20.2 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 EMC90154.1 - 0.0031 16.0 0.0 0.0055 15.2 0.0 1.4 2 0 0 2 2 2 1 Ndr family Lipase_3 PF01764.20 EMC90154.1 - 0.0043 16.6 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EMC90154.1 - 0.033 12.9 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EMC90154.1 - 0.048 12.5 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.15 EMC90154.1 - 0.051 13.7 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF1057 PF06342.7 EMC90154.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.8 EMC90154.1 - 0.14 10.4 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PMP22_Claudin PF00822.15 EMC90155.1 - 1.3e-32 112.7 10.9 1.5e-32 112.5 7.5 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC90155.1 - 1e-09 38.3 10.8 1e-09 38.3 7.5 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trep_Strep PF09605.5 EMC90155.1 - 0.01 15.5 1.4 0.5 10.0 0.0 2.3 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) COPI_assoc PF08507.5 EMC90155.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.5 3 0 0 3 3 3 0 COPI associated protein DUF3185 PF11381.3 EMC90155.1 - 0.23 11.2 6.4 2.1 8.2 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) DUF872 PF05915.7 EMC90155.1 - 1 9.2 4.7 0.55 10.0 0.2 2.4 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF4064 PF13273.1 EMC90155.1 - 2.8 8.0 9.3 4.1 7.5 5.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) SUR7 PF06687.7 EMC90155.1 - 9.4 5.7 11.5 40 3.6 7.9 1.9 1 1 0 1 1 1 0 SUR7/PalI family DUF1510 PF07423.6 EMC90156.1 - 0.069 12.5 6.9 0.083 12.2 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PMP22_Claudin PF00822.15 EMC90157.1 - 4.1e-34 117.6 10.9 4.9e-34 117.3 7.6 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC90157.1 - 1.3e-12 47.7 4.2 1.3e-12 47.7 2.9 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF872 PF05915.7 EMC90157.1 - 6e-05 22.8 0.6 6e-05 22.8 0.4 2.6 3 0 0 3 3 3 1 Eukaryotic protein of unknown function (DUF872) SUR7 PF06687.7 EMC90157.1 - 0.0067 16.0 1.7 0.0067 16.0 1.2 2.1 1 1 0 2 2 2 1 SUR7/PalI family DUF3185 PF11381.3 EMC90157.1 - 0.0097 15.6 13.4 0.017 14.8 3.8 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3185) Neurensin PF14927.1 EMC90157.1 - 0.089 12.1 0.1 0.089 12.1 0.1 2.7 3 0 0 3 3 3 0 Neurensin TMEM240 PF15207.1 EMC90157.1 - 0.19 11.2 4.1 2.5 7.6 0.3 2.6 2 1 0 2 2 2 0 TMEM240 family TMEM37 PF15108.1 EMC90157.1 - 0.4 10.3 9.8 0.08 12.6 4.5 1.5 2 0 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF4064 PF13273.1 EMC90157.1 - 0.84 9.7 13.4 0.06 13.4 1.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) MgtC PF02308.11 EMC90157.1 - 1.3 8.8 6.9 0.1 12.4 1.2 1.7 2 0 0 2 2 2 0 MgtC family SepZ PF06066.6 EMC90157.1 - 3.8 7.5 6.0 5.5 7.0 1.3 2.8 3 0 0 3 3 3 0 SepZ TctB PF07331.6 EMC90157.1 - 4 7.1 9.9 0.76 9.4 2.6 2.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF308 PF03729.8 EMC90157.1 - 6.1 6.9 17.0 4.4 7.3 6.0 3.4 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) CD20 PF04103.10 EMC90157.1 - 7 6.5 13.3 0.12 12.3 1.5 2.5 2 1 1 3 3 3 0 CD20-like family PMP22_Claudin PF00822.15 EMC90158.1 - 5.2e-31 107.5 10.3 6.1e-31 107.3 7.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC90158.1 - 3.6e-09 36.5 5.7 3.6e-09 36.5 4.0 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction COPI_assoc PF08507.5 EMC90158.1 - 0.014 15.0 2.1 0.015 14.9 0.1 2.0 2 0 0 2 2 2 0 COPI associated protein DUF308 PF03729.8 EMC90158.1 - 0.057 13.4 1.4 0.057 13.4 1.0 3.0 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF3185 PF11381.3 EMC90158.1 - 0.081 12.7 0.3 0.081 12.7 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) IncA PF04156.9 EMC90158.1 - 0.2 11.2 0.2 0.2 11.2 0.2 3.3 4 1 0 4 4 4 0 IncA protein YtpI PF14007.1 EMC90158.1 - 0.52 10.2 3.4 9.2 6.2 2.2 2.4 1 1 0 1 1 1 0 YtpI-like protein DUF1129 PF06570.6 EMC90158.1 - 1.1 8.5 5.9 1.2 8.3 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF418 PF04235.7 EMC90158.1 - 1.3 8.6 7.6 0.65 9.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF418) Amastin PF07344.6 EMC90158.1 - 2.8 7.5 10.4 0.57 9.7 4.1 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein PsbX PF06596.6 EMC90158.1 - 5.8 6.6 8.5 30 4.4 0.1 2.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) PT PF04886.7 EMC90160.1 - 2.9e-12 45.6 1.3 0.014 14.7 0.9 4.4 1 1 0 1 1 1 1 PT repeat Pkinase_Tyr PF07714.12 EMC90161.1 - 4.3e-47 160.3 0.0 6.1e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMC90161.1 - 2.7e-46 157.8 0.0 3.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.17 EMC90161.1 - 5.9e-20 71.0 19.1 5.2e-14 52.0 5.2 2.6 2 0 0 2 2 2 2 LIM domain PDZ PF00595.19 EMC90161.1 - 4.2e-10 39.6 0.0 9.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Kdo PF06293.9 EMC90161.1 - 1.1e-05 24.6 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC90161.1 - 0.00098 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMC90161.1 - 0.011 14.7 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Kinase-like PDZ_2 PF13180.1 EMC90161.1 - 0.022 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain RIO1 PF01163.17 EMC90161.1 - 0.024 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ANTH PF07651.11 EMC90162.1 - 1.4e-83 279.8 0.4 1.7e-83 279.5 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EMC90162.1 - 1.5e-14 53.8 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 EMC90162.1 - 0.066 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain Trypsin PF00089.21 EMC90163.1 - 8.4e-12 45.1 0.0 5.2e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.1 EMC90163.1 - 5.8e-06 26.2 0.0 1.8e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain LAP1C PF05609.7 EMC90163.1 - 0.023 13.4 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF316 PF03761.10 EMC90163.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Malic_M PF03949.10 EMC90164.1 - 4.8e-84 281.8 0.0 6.5e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMC90164.1 - 6.4e-81 270.2 0.0 1e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF1115 PF06544.7 EMC90165.1 - 2.4e-25 88.6 0.2 4e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 EMC90165.1 - 2.2e-13 50.0 0.0 4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF950 PF06106.6 EMC90165.1 - 0.0078 16.2 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Staphylococcus protein of unknown function (DUF950) Prok-E2_E PF14462.1 EMC90165.1 - 0.033 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E Acylphosphatase PF00708.13 EMC90165.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase THDPS_N_2 PF14805.1 EMC90165.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PGM_PMM_I PF02878.11 EMC90166.1 - 3.4e-20 71.9 0.2 8.8e-09 34.9 0.0 3.6 2 2 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EMC90166.1 - 4.2e-11 42.6 0.1 1.5e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 EMC90166.1 - 4.4e-10 39.8 0.0 2.6e-09 37.3 0.0 2.4 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EMC90166.1 - 0.00066 19.6 0.5 0.0019 18.2 0.3 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Dopey_N PF04118.9 EMC90167.1 - 1.8e-106 355.3 0.1 1e-105 352.9 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal LRR_8 PF13855.1 EMC90169.1 - 2.1e-20 72.1 7.5 7.3e-16 57.6 3.1 2.8 2 2 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EMC90169.1 - 4e-12 45.4 13.9 0.00027 20.4 0.6 3.9 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC90169.1 - 2.6e-11 41.9 15.9 0.025 14.5 0.0 5.4 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EMC90169.1 - 5e-08 31.8 16.7 0.069 13.3 0.0 5.5 4 1 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 EMC90169.1 - 9.9e-07 28.2 11.9 1.2 9.4 1.0 4.8 4 1 1 5 5 5 4 Leucine Rich repeat LRR_9 PF14580.1 EMC90169.1 - 0.00071 19.1 0.8 0.0048 16.4 0.3 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRRNT PF01462.13 EMC90169.1 - 0.021 14.2 0.2 0.038 13.4 0.2 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain RCC1 PF00415.13 EMC90170.1 - 2.4e-36 123.6 13.8 2.6e-11 43.5 0.7 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EMC90170.1 - 3.9e-32 110.5 7.4 7.1e-16 58.1 0.8 3.0 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 EMC90170.1 - 5.3e-13 48.7 0.0 1.3e-06 28.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EMC90170.1 - 1.7e-10 40.2 8.6 0.00068 19.1 0.0 6.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.25 EMC90170.1 - 4.4e-09 35.6 0.0 8.9e-05 22.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMC90170.1 - 4.7e-09 36.5 0.0 1.5e-05 25.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC90170.1 - 1.2e-08 35.1 0.0 4e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMC90170.1 - 0.00011 22.0 0.0 1.4 9.4 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Transket_pyr PF02779.19 EMC90171.1 - 1.1e-43 148.7 0.0 1.5e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMC90171.1 - 4.3e-36 123.5 0.0 1.3e-35 122.0 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Hormone_recep PF00104.25 EMC90172.1 - 1.4e-17 63.4 0.8 1.9e-17 63.0 0.5 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Pkinase PF00069.20 EMC90173.1 - 6.6e-63 212.2 1.0 1e-62 211.6 0.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90173.1 - 7.9e-34 116.9 0.1 1.6e-33 115.9 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC90173.1 - 5.8e-10 38.5 0.0 2.4e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMC90173.1 - 2.9e-06 27.1 0.0 0.065 12.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMC90173.1 - 0.00018 20.6 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC90173.1 - 0.00086 18.6 3.1 0.007 15.7 0.1 2.2 1 1 1 2 2 2 1 RIO1 family Tubulin PF00091.20 EMC90173.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF1258 PF06869.7 EMC90174.1 - 0.014 14.4 0.0 0.73 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) DUF573 PF04504.9 EMC90174.1 - 0.027 14.7 0.3 0.068 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 TPR_12 PF13424.1 EMC90174.1 - 0.035 14.0 0.4 8.2 6.4 0.0 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EMC90174.1 - 0.081 12.7 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 EMC90174.1 - 0.11 12.4 0.4 22 5.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ELO PF01151.13 EMC90175.1 - 5.1e-65 219.2 28.0 5.8e-65 219.0 19.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SH3BGR PF04908.10 EMC90176.1 - 5.5e-38 128.9 0.2 6.2e-38 128.7 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EMC90176.1 - 2.1e-07 30.7 0.0 2.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Lebercilin PF15619.1 EMC90177.1 - 2.4e-71 239.1 52.8 2.4e-71 239.1 36.6 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease FUSC PF04632.7 EMC90177.1 - 1.5 7.1 9.1 2.3 6.5 6.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 EMC90177.1 - 6.8 6.2 62.9 0.12 11.9 15.2 3.1 2 1 1 3 3 3 0 IncA protein HMG14_17 PF01101.13 EMC90178.1 - 1.3e-23 83.4 19.7 1.8e-23 83.0 13.6 1.1 1 0 0 1 1 1 1 HMG14 and HMG17 TT_ORF2 PF02957.10 EMC90178.1 - 0.68 10.6 6.8 0.93 10.2 4.7 1.3 1 0 0 1 1 1 0 TT viral ORF2 Pox_Ag35 PF03286.9 EMC90178.1 - 1 8.8 8.2 1.2 8.6 5.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2477 PF10631.4 EMC90178.1 - 2.6 8.2 5.4 3.3 7.9 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) DUF566 PF04484.7 EMC90178.1 - 4.4 6.7 8.1 5.1 6.5 5.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) WD40 PF00400.27 EMC90179.1 - 2.3e-47 157.2 18.5 8.5e-08 31.8 0.0 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Bromodomain PF00439.20 EMC90179.1 - 2e-37 126.9 0.1 1.2e-17 63.5 0.0 2.7 2 0 0 2 2 2 2 Bromodomain YccV-like PF08755.6 EMC90180.1 - 2.3e-23 81.9 0.5 4.3e-23 81.1 0.1 1.6 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like SIMPL PF04402.9 EMC90181.1 - 7.1e-07 29.3 0.0 7.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF541) HVSL PF09749.4 EMC90181.1 - 0.083 11.8 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein Mei4 PF13971.1 EMC90182.1 - 2.6e-83 280.0 11.9 3.1e-83 279.8 8.2 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Glt_symporter PF03616.9 EMC90182.1 - 0.22 10.0 1.3 0.32 9.4 0.9 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter 7tm_1 PF00001.16 EMC90183.1 - 3.1e-90 301.7 12.3 4e-90 301.4 8.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90183.1 - 6.8e-11 41.8 10.2 6.4e-10 38.6 7.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC90183.1 - 5.4e-06 25.7 4.7 5.4e-06 25.7 3.2 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ABC2_membrane_2 PF12679.2 EMC90183.1 - 0.17 10.7 13.8 2.2 7.0 0.5 2.8 1 1 1 2 2 2 0 ABC-2 family transporter protein SEA PF01390.15 EMC90184.1 - 3e-43 145.8 2.6 6.4e-21 74.0 0.1 2.5 2 0 0 2 2 2 2 SEA domain Myosin_head PF00063.16 EMC90185.1 - 1.2e-222 740.8 1.3 1.2e-222 740.8 0.9 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 EMC90185.1 - 0.0028 17.1 0.8 0.0072 15.8 0.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif MIP-T3 PF10243.4 EMC90185.1 - 0.02 13.4 40.1 0.031 12.7 27.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Myosin_N PF02736.14 EMC90185.1 - 0.037 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EMC90185.1 - 0.68 10.0 0.0 0.68 10.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain Peptidase_C48 PF02902.14 EMC90186.1 - 3.3e-33 115.1 5.0 7e-20 71.5 0.2 2.7 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain CortBP2 PF09727.4 EMC90187.1 - 6.3e-83 277.0 26.4 6.3e-83 277.0 18.3 7.0 3 2 4 7 7 7 2 Cortactin-binding protein-2 DUF3596 PF12167.3 EMC90187.1 - 0.096 12.2 1.1 0.3 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) BAAT_C PF08840.6 EMC90187.1 - 1.3 8.6 10.4 0.058 13.0 1.6 2.9 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Reo_sigmaC PF04582.7 EMC90187.1 - 3.4 6.7 27.6 0.23 10.5 2.2 4.2 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 EMC90187.1 - 7.8 6.3 11.2 35 4.2 0.2 5.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 CDC50 PF03381.10 EMC90188.1 - 3.1e-98 328.3 0.2 3.6e-98 328.1 0.2 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family COX7a PF02238.10 EMC90189.1 - 3.4e-16 58.6 0.0 4.3e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa MFS_1 PF07690.11 EMC90190.1 - 9.3e-58 195.6 33.8 2.1e-56 191.1 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMC90190.1 - 5.6e-07 28.4 25.1 8.6e-06 24.5 17.4 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter GTP_EFTU PF00009.22 EMC90191.1 - 1.1e-56 191.2 0.0 1.6e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMC90191.1 - 2.6e-36 123.7 0.0 7.6e-36 122.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMC90191.1 - 1.6e-17 63.4 1.0 1.6e-17 63.4 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EMC90191.1 - 3e-05 23.5 0.2 9.3e-05 21.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EMC90191.1 - 0.00068 19.5 0.4 0.002 18.0 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMC90191.1 - 0.048 13.4 0.1 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family GIDA PF01134.17 EMC90192.1 - 2.9e-96 322.7 0.0 3.9e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EMC90192.1 - 7.5e-20 70.7 0.0 1.7e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 Hexapep_2 PF14602.1 EMC90192.1 - 0.097 12.2 0.7 0.2 11.2 0.5 1.5 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Mab-21 PF03281.9 EMC90193.1 - 9.7e-61 205.4 6.2 1.1e-60 205.2 4.3 1.0 1 0 0 1 1 1 1 Mab-21 protein DEAD PF00270.24 EMC90194.1 - 4.8e-35 120.5 0.0 2.7e-34 118.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMC90194.1 - 3e-26 91.0 0.1 2.3e-25 88.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_1 PF00013.24 EMC90194.1 - 7.7e-06 25.4 1.1 1.8e-05 24.2 0.8 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC90194.1 - 8.8e-06 25.2 0.7 1.8e-05 24.2 0.5 1.6 1 0 0 1 1 1 1 KH domain ResIII PF04851.10 EMC90194.1 - 0.0031 17.3 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMC90194.1 - 0.03 13.1 0.0 0.081 11.6 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain KCNQ_channel PF03520.9 EMC90195.1 - 1.4e-91 305.3 1.5 3.1e-91 304.1 1.1 1.6 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.26 EMC90195.1 - 8.6e-26 90.4 11.1 1.7e-25 89.4 7.7 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EMC90195.1 - 1.5e-13 50.2 5.8 4.3e-13 48.7 4.0 1.8 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.7 EMC90195.1 - 0.059 11.7 3.4 0.025 13.0 0.5 1.6 1 1 1 2 2 2 0 Polycystin cation channel IQ PF00612.22 EMC90195.1 - 0.47 10.2 0.1 0.47 10.2 0.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif C2 PF00168.25 EMC90196.1 - 1.4e-34 117.7 0.0 3.1e-17 62.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain PDZ PF00595.19 EMC90196.1 - 3.1e-10 40.0 0.0 6.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FYVE_2 PF02318.11 EMC90196.1 - 3.2e-07 30.2 6.8 9.5e-07 28.7 4.7 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger Asparaginase_2 PF01112.13 EMC90197.1 - 1.2e-77 260.8 3.5 1.5e-77 260.4 2.4 1.1 1 0 0 1 1 1 1 Asparaginase OGFr_N PF04664.8 EMC90198.1 - 2.4e-91 304.8 7.9 3.2e-91 304.4 5.5 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Glyco_transf_43 PF03360.11 EMC90199.1 - 9e-42 142.9 0.1 1e-41 142.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 ArfGap PF01412.13 EMC90200.1 - 6.9e-33 112.8 0.1 6.9e-33 112.8 0.1 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf SR-25 PF10500.4 EMC90200.1 - 0.00029 20.3 11.9 0.00029 20.3 8.2 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein GAGA_bind PF06217.7 EMC90200.1 - 0.14 12.1 7.5 0.26 11.2 5.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 EMC90200.1 - 1.2 7.8 15.1 1.8 7.2 10.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 EMC90200.1 - 5.2 6.7 11.3 0.9 9.2 5.1 1.7 2 0 0 2 2 2 0 DDHD domain DUF1674 PF07896.7 EMC90203.1 - 3.3e-19 68.8 6.5 5.1e-19 68.2 4.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF676 PF05057.9 EMC90204.1 - 5.4e-61 205.6 0.0 9.6e-61 204.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 EMC90204.1 - 1.9e-29 101.5 6.2 3.1e-18 65.5 1.5 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3657) PGAP1 PF07819.8 EMC90204.1 - 2.7e-05 23.8 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 EMC90204.1 - 8.7e-05 21.6 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase LMBR1 PF04791.11 EMC90206.1 - 1.7e-16 59.8 17.6 8.9e-16 57.5 1.7 2.5 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF4294 PF14127.1 EMC90206.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) 7tm_2 PF00002.19 EMC90207.1 - 3.3e-62 209.7 15.1 4.6e-62 209.2 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3497 PF12003.3 EMC90207.1 - 1.2e-48 165.3 0.1 1.8e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) TSP_1 PF00090.14 EMC90207.1 - 4.1e-33 113.2 79.7 2.3e-12 46.8 5.9 5.8 5 1 0 5 5 5 3 Thrombospondin type 1 domain GPS PF01825.16 EMC90207.1 - 8.4e-14 51.4 2.5 8.4e-14 51.4 1.7 3.0 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 EMC90207.1 - 5.9e-08 32.6 0.4 5.9e-08 32.6 0.3 4.1 3 1 0 3 3 3 1 Hormone receptor domain NDUF_B12 PF08122.7 EMC90207.1 - 0.018 14.7 0.1 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family EGF PF00008.22 EMC90210.1 - 3e-66 218.8 151.0 2.4e-08 33.7 3.3 11.4 11 0 0 11 11 11 11 EGF-like domain EGF_CA PF07645.10 EMC90210.1 - 9.2e-26 89.5 157.6 9.7e-06 25.4 2.2 11.4 8 3 3 11 11 11 10 Calcium-binding EGF domain hEGF PF12661.2 EMC90210.1 - 6.2e-22 76.1 102.1 0.00048 20.0 2.1 13.1 12 0 0 12 12 12 10 Human growth factor-like EGF EGF_2 PF07974.8 EMC90210.1 - 3.8e-09 36.5 166.1 0.00023 21.2 5.1 11.4 10 1 1 11 11 11 8 EGF-like domain FXa_inhibition PF14670.1 EMC90210.1 - 2e-08 34.2 130.7 0.053 13.6 1.4 11.8 6 4 5 11 11 11 8 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EMC90210.1 - 3.5e-07 30.0 131.1 0.088 12.7 5.6 12.0 9 2 2 11 11 11 9 EGF domain cEGF PF12662.2 EMC90210.1 - 0.003 17.1 11.9 0.011 15.4 0.7 13.2 13 1 0 13 13 13 9 Complement Clr-like EGF-like Y_phosphatase PF00102.22 EMC90212.1 - 3.4e-13 49.4 0.0 1.1e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EMC90212.1 - 3.1e-09 36.5 0.0 4.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMC90212.1 - 0.036 14.3 0.2 0.37 11.0 0.1 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC90212.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Gln-synt_C PF00120.19 EMC90213.1 - 4.4e-47 160.4 0.0 7.8e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EMC90213.1 - 4.4e-07 29.3 1.4 1.1e-06 28.0 0.1 2.5 3 1 0 3 3 3 1 Glutamine synthetase, beta-Grasp domain DUF1236 PF06823.7 EMC90214.1 - 0.48 10.1 6.8 9.1 6.0 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1236) zf-RING_2 PF13639.1 EMC90216.1 - 9.2e-10 38.2 10.0 9.2e-10 38.2 6.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMC90216.1 - 5.2e-09 35.6 4.3 5.2e-09 35.6 3.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC90216.1 - 7.7e-09 35.0 7.3 1.7e-08 33.9 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC90216.1 - 4.5e-08 32.9 9.7 4.5e-08 32.9 6.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMC90216.1 - 1.3e-07 31.5 5.2 4.1e-07 30.0 3.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMC90216.1 - 3.8e-07 29.7 5.4 1.1e-06 28.2 3.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMC90216.1 - 2.8e-05 23.9 7.8 8.7e-05 22.3 5.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMC90216.1 - 6.4e-05 22.5 1.0 6.4e-05 22.5 0.7 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EMC90216.1 - 0.026 14.2 3.7 0.055 13.2 2.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EMC90216.1 - 0.053 13.3 4.5 0.14 12.0 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.7 EMC90216.1 - 0.058 13.5 1.8 6.9 6.8 0.2 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 EMC90216.1 - 0.14 11.6 1.6 0.28 10.7 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.6 EMC90216.1 - 0.39 10.4 5.1 0.65 9.7 3.5 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EMC90216.1 - 7.3 6.2 10.2 68 3.1 7.0 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 KH_1 PF00013.24 EMC90217.1 - 4.2e-06 26.2 0.0 9.8e-06 25.1 0.0 1.7 1 1 0 1 1 1 1 KH domain KH_3 PF13014.1 EMC90217.1 - 1.4e-05 24.5 0.0 4.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 KH domain DNA_primase_lrg PF04104.9 EMC90219.1 - 6.2e-91 304.2 0.0 1.3e-90 303.1 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Ras PF00071.17 EMC90220.1 - 5e-53 178.7 1.2 8.1e-53 178.1 0.9 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC90220.1 - 1.7e-19 70.4 0.2 3e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC90220.1 - 2.5e-10 39.8 0.8 3.4e-10 39.4 0.6 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMC90220.1 - 9.5e-07 28.7 0.1 2.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMC90220.1 - 9e-06 25.2 0.4 3.4e-05 23.3 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMC90220.1 - 6.4e-05 22.2 0.2 0.00011 21.4 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMC90220.1 - 0.0007 19.2 3.3 0.0015 18.1 0.4 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EMC90220.1 - 0.011 14.9 0.3 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B YwhD PF08741.5 EMC90220.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 YwhD family MobB PF03205.9 EMC90220.1 - 0.15 11.8 0.6 0.38 10.4 0.2 1.9 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B BAG PF02179.11 EMC90221.1 - 7.2e-07 29.2 0.9 1.2e-06 28.5 0.2 1.7 2 0 0 2 2 2 1 BAG domain DUF4168 PF13767.1 EMC90221.1 - 0.029 15.0 0.1 0.063 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) SidE PF12252.3 EMC90221.1 - 0.098 9.9 2.0 0.79 6.9 0.1 2.0 2 0 0 2 2 2 0 Dot/Icm substrate protein DUF4347 PF14252.1 EMC90221.1 - 0.1 12.1 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) DUF4158 PF13700.1 EMC90221.1 - 0.11 11.9 0.3 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Enkurin PF13864.1 EMC90221.1 - 0.39 10.9 4.8 6.9 6.9 0.5 2.3 2 0 0 2 2 2 0 Calmodulin-binding Prefoldin PF02996.12 EMC90221.1 - 1.6 8.3 6.7 1.1 8.8 0.4 2.4 2 1 0 2 2 2 0 Prefoldin subunit BEN PF10523.4 EMC90223.1 - 3.6e-08 33.3 0.0 8.2e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 BEN domain ImcF-related_N PF14331.1 EMC90223.1 - 0.018 13.9 0.6 0.15 10.9 0.1 2.0 2 0 0 2 2 2 0 ImcF-related N-terminal domain RCR PF12273.3 EMC90224.1 - 0.17 12.4 2.3 0.18 12.3 0.3 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF4131 PF13567.1 EMC90224.1 - 3.1 7.1 4.6 0.87 8.9 1.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Spectrin PF00435.16 EMC90225.1 - 4e-220 714.9 474.7 1.3e-16 60.7 5.0 42.0 40 3 4 44 44 44 33 Spectrin repeat GAS2 PF02187.12 EMC90225.1 - 1.3e-34 117.7 1.0 3.9e-34 116.2 0.7 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 EMC90225.1 - 3.2e-34 117.2 20.3 6.8e-17 61.4 0.1 8.8 8 0 0 8 8 8 2 Calponin homology (CH) domain EF-hand_1 PF00036.27 EMC90225.1 - 2.4e-12 45.1 2.3 5.5e-05 22.1 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMC90225.1 - 1.1e-10 41.5 0.6 1.6e-09 37.7 0.4 3.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC90225.1 - 6.4e-10 38.0 2.4 0.00066 19.3 0.4 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMC90225.1 - 4.7e-09 35.7 0.3 3.3e-07 29.7 0.1 3.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMC90225.1 - 1.1e-08 33.9 4.1 3.9e-05 22.7 1.0 3.1 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 EMC90225.1 - 1.6e-07 30.8 3.0 4.5e-05 23.0 0.0 4.8 4 0 0 4 4 4 1 CAMSAP CH domain Laminin_II PF06009.7 EMC90225.1 - 0.015 15.0 0.2 0.015 15.0 0.1 30.8 23 8 11 36 36 36 0 Laminin Domain II Collagen PF01391.13 EMC90226.1 - 2.5e-62 206.3 222.9 1.7e-09 37.0 17.0 8.2 3 3 5 8 8 8 8 Collagen triple helix repeat (20 copies) VWA PF00092.23 EMC90226.1 - 1.3e-43 148.8 0.1 1.8e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMC90226.1 - 4.4e-14 52.9 0.0 6.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_3 PF13385.1 EMC90226.1 - 0.00011 22.5 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily VWA_3 PF13768.1 EMC90226.1 - 0.00042 20.0 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_2 PF02210.19 EMC90226.1 - 0.0078 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain vWA-TerF-like PF10138.4 EMC90226.1 - 0.27 11.0 0.0 0.81 9.4 0.0 1.7 1 1 1 2 2 2 0 vWA found in TerF C terminus TGFb_propeptide PF00688.13 EMC90227.1 - 1e-57 195.2 0.4 3e-57 193.6 0.3 1.8 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 EMC90227.1 - 4.5e-44 149.0 1.0 1e-43 147.8 0.7 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain HMGL-like PF00682.14 EMC90228.1 - 1.9e-66 224.1 0.0 2.2e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 HMGL-like 7tm_1 PF00001.16 EMC90230.1 - 2.8e-59 200.3 22.0 3.7e-59 199.9 15.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orexin_rec2 PF03827.8 EMC90230.1 - 4.2e-25 87.5 2.7 4.4e-25 87.5 0.3 2.2 2 0 0 2 2 2 1 Orexin receptor type 2 7TM_GPCR_Srsx PF10320.4 EMC90230.1 - 0.00015 21.0 21.2 0.00058 19.0 14.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2231 PF09990.4 EMC90230.1 - 1.1 9.6 7.8 0.23 11.8 2.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) ABC2_membrane_5 PF13346.1 EMC90230.1 - 3.2 6.9 21.2 0.99 8.6 4.7 3.3 3 1 1 4 4 4 0 ABC-2 family transporter protein DUF1669 PF07894.7 EMC90231.1 - 1.5e-106 355.7 0.0 1.5e-106 355.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 EMC90231.1 - 1.1e-08 34.9 0.1 2.4e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 PLD-like domain Regulator_TrmB PF11495.3 EMC90231.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Peptidase_C1 PF00112.18 EMC90232.1 - 1.7e-53 181.7 8.6 1.7e-53 181.7 6.0 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Pacifastin_I PF05375.8 EMC90232.1 - 0.00051 19.4 2.6 0.00051 19.4 1.8 2.4 2 0 0 2 2 2 1 Pacifastin inhibitor (LCMII) Somatomedin_B PF01033.12 EMC90232.1 - 0.02 14.8 17.6 0.02 14.8 12.2 2.6 2 0 0 2 2 2 0 Somatomedin B domain Peptidase_C1_2 PF03051.10 EMC90232.1 - 0.057 11.9 2.9 0.062 11.8 0.6 2.0 2 1 1 3 3 3 0 Peptidase C1-like family Propeptide_C1 PF08127.8 EMC90232.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C1 propeptide MLIP PF15274.1 EMC90233.1 - 6.7e-72 242.0 3.1 1.2e-71 241.2 2.2 1.4 1 1 0 1 1 1 1 Muscular LMNA-interacting protein LRR_4 PF12799.2 EMC90234.1 - 3.1e-45 151.1 50.4 9.1e-09 34.7 2.0 9.1 5 3 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC90234.1 - 2e-34 117.1 37.5 2.5e-09 36.7 3.6 7.0 3 2 3 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EMC90234.1 - 7.4e-25 83.1 47.4 0.099 12.7 0.0 14.6 15 0 0 15 15 15 10 Leucine Rich Repeat LRR_7 PF13504.1 EMC90234.1 - 9.5e-13 46.1 50.3 0.34 11.2 0.0 14.9 15 0 0 15 15 15 6 Leucine rich repeat LRR_9 PF14580.1 EMC90234.1 - 2.9e-07 30.2 13.3 0.0028 17.2 2.3 4.2 2 1 2 4 4 4 3 Leucine-rich repeat Tropomyosin_1 PF12718.2 EMC90234.1 - 0.097 12.5 2.3 0.24 11.2 1.6 1.6 1 0 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.4 EMC90234.1 - 0.22 11.6 2.7 0.35 11.0 0.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Elongin_A PF06881.6 EMC90235.1 - 1.9e-32 111.9 0.7 1.9e-32 111.9 0.5 2.5 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.6 EMC90235.1 - 8.4e-15 54.0 0.8 2.2e-14 52.6 0.5 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Kelch_1 PF01344.20 EMC90236.1 - 1.8e-50 168.2 7.9 3.1e-12 45.8 0.0 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EMC90236.1 - 2e-36 122.6 5.4 4e-09 36.2 0.1 6.1 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 EMC90236.1 - 1.3e-25 89.1 1.0 2.4e-25 88.3 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 EMC90236.1 - 1e-23 82.8 0.7 3.8e-06 26.8 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain BTB PF00651.26 EMC90236.1 - 3.8e-23 81.5 1.2 6.2e-23 80.9 0.3 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 EMC90236.1 - 2e-22 78.6 0.3 0.00015 21.4 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMC90236.1 - 6.4e-20 70.0 5.4 2.3e-07 30.3 0.1 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EMC90236.1 - 6.8e-14 51.4 5.4 0.0018 18.2 0.1 5.6 5 0 0 5 5 5 4 Kelch motif DUF1668 PF07893.8 EMC90236.1 - 0.041 12.9 0.0 0.17 10.9 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1668) ORF6N PF10543.4 EMC90236.1 - 0.12 12.4 0.2 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 ORF6N domain GCS PF03074.11 EMC90237.1 - 2.4e-198 658.6 0.3 2.9e-198 658.3 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 EMC90237.1 - 0.021 13.9 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) GCM PF03615.10 EMC90238.1 - 8.5e-75 249.1 5.0 1.1e-74 248.7 3.5 1.1 1 0 0 1 1 1 1 GCM motif protein F-box-like PF12937.2 EMC90239.1 - 1.3e-11 44.0 1.5 2.4e-11 43.1 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMC90239.1 - 3e-08 33.1 1.5 5.5e-08 32.2 1.0 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 EMC90239.1 - 0.0003 20.5 0.6 0.00052 19.8 0.4 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EMC90239.1 - 0.043 13.4 0.2 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 TPR repeat VGCC_alpha2 PF08473.6 EMC90239.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Pkinase PF00069.20 EMC90240.1 - 2.2e-75 253.1 0.0 3.6e-75 252.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90240.1 - 2.5e-37 128.3 0.1 1e-36 126.3 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC90240.1 - 0.0069 15.3 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like tRNA-synt_1g PF09334.6 EMC90240.1 - 0.092 11.3 0.3 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) GST_N PF02798.15 EMC90241.1 - 2.9e-20 72.1 0.0 8.3e-20 70.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC90241.1 - 2.3e-15 56.3 0.1 6.5e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC90241.1 - 0.00071 19.4 0.2 0.0026 17.5 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC90241.1 - 0.0014 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC90241.1 - 0.052 14.0 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC90242.1 - 3.8e-16 59.0 0.0 1.3e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC90242.1 - 2.1e-15 56.4 0.0 4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC90242.1 - 0.0014 19.0 0.0 0.0023 18.3 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC90242.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC90242.1 - 0.028 14.6 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMC90243.1 - 8.9e-16 57.8 0.0 1.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC90243.1 - 3.1e-14 52.7 0.1 4.9e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC90243.1 - 0.01 16.0 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMC90243.1 - 0.021 15.2 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC90243.1 - 0.036 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC90244.1 - 5.3e-17 61.7 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC90244.1 - 3.9e-14 52.3 0.2 9.1e-14 51.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC90244.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC90244.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC90244.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMC90245.1 - 4.7e-18 65.1 0.0 1e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC90245.1 - 1.7e-16 59.9 0.0 3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMC90245.1 - 0.00012 22.2 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC90245.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC90245.1 - 0.039 14.4 0.0 0.066 13.6 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tmemb_14 PF03647.8 EMC90246.1 - 2.8e-29 101.3 7.3 3.2e-29 101.1 5.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gly-zipper_OmpA PF13436.1 EMC90246.1 - 0.087 12.4 0.6 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF2232 PF09991.4 EMC90246.1 - 0.095 11.6 6.4 0.11 11.4 4.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PMT_2 PF13231.1 EMC90246.1 - 0.1 12.5 4.8 0.12 12.2 3.3 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase UbiA PF01040.13 EMC90246.1 - 0.26 10.4 6.2 0.42 9.7 4.3 1.5 1 1 0 1 1 1 0 UbiA prenyltransferase family YjgP_YjgQ PF03739.9 EMC90246.1 - 1.9 7.1 5.4 3.1 6.4 3.7 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4131 PF13567.1 EMC90246.1 - 2.9 7.2 7.4 5.7 6.3 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) BRCT PF00533.21 EMC90247.1 - 1.8e-18 66.4 4.4 2.3e-05 24.4 0.0 3.8 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMC90247.1 - 8.5e-18 63.9 3.6 1.1e-15 57.1 0.8 3.4 3 0 0 3 3 3 1 twin BRCT domain TBPIP PF07106.8 EMC90247.1 - 0.022 14.2 0.7 0.052 13.0 0.5 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Barwin PF00967.12 EMC90247.1 - 0.049 13.3 0.1 0.24 11.0 0.0 2.2 3 0 0 3 3 3 0 Barwin family Spectrin PF00435.16 EMC90247.1 - 0.085 13.1 0.8 2.2 8.5 1.0 2.6 1 1 0 1 1 1 0 Spectrin repeat Fibrinogen_C PF00147.13 EMC90248.1 - 6.2e-66 222.3 7.2 1.2e-65 221.4 5.0 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SlyX PF04102.7 EMC90248.1 - 0.026 14.8 24.7 0.13 12.6 5.5 3.1 1 1 2 3 3 3 0 SlyX DivIC PF04977.10 EMC90248.1 - 0.037 13.5 17.9 0.026 14.0 2.3 3.5 1 1 1 3 3 3 0 Septum formation initiator Phage_lysis PF03245.8 EMC90248.1 - 7 6.6 15.5 0.21 11.5 4.1 2.9 1 1 2 3 3 3 0 Bacteriophage Rz lysis protein CUB PF00431.15 EMC90249.1 - 1.6e-15 57.1 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.15 EMC90249.1 - 1.2e-08 35.1 0.1 2.1e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) 5_nucleotid PF05761.9 EMC90250.1 - 1.3e-32 112.8 0.2 1.6e-32 112.6 0.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family CUB PF00431.15 EMC90251.1 - 3.4e-284 921.8 0.0 1.7e-27 95.6 0.0 13.4 13 0 0 13 13 13 13 CUB domain Sushi PF00084.15 EMC90251.1 - 4.1e-254 821.2 180.5 2.2e-11 43.9 0.8 27.6 27 0 0 27 27 27 27 Sushi domain (SCR repeat) CUB_2 PF02408.15 EMC90251.1 - 5.1e-21 74.4 9.5 0.0044 16.5 0.0 10.6 12 0 0 12 12 12 6 CUB-like domain fn3 PF00041.16 EMC90252.1 - 1.4e-86 284.6 14.8 7.8e-19 67.5 0.1 6.3 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.11 EMC90252.1 - 4.2e-68 225.2 9.9 5.6e-21 74.2 0.0 8.3 9 0 0 9 9 9 7 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90252.1 - 2.4e-36 123.7 0.3 7.9e-08 32.3 0.0 7.0 7 0 0 7 7 7 5 Immunoglobulin domain Ig_3 PF13927.1 EMC90252.1 - 1.1e-22 80.2 0.9 5.7e-06 26.7 0.0 7.7 8 0 0 8 8 7 3 Immunoglobulin domain V-set PF07686.12 EMC90252.1 - 2.1e-20 72.7 9.0 6.7e-05 22.7 0.0 9.1 7 2 0 7 7 7 4 Immunoglobulin V-set domain ig PF00047.20 EMC90252.1 - 1.5e-18 66.6 6.1 1.3e-08 34.8 0.0 7.5 8 0 0 8 8 8 4 Immunoglobulin domain Tissue_fac PF01108.12 EMC90252.1 - 2.1e-10 40.2 0.1 0.0063 16.2 0.0 5.4 5 0 0 5 5 5 2 Tissue factor C2-set_2 PF08205.7 EMC90252.1 - 7.8e-08 32.1 0.1 0.098 12.5 0.0 4.3 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC90252.1 - 1.1e-06 27.2 0.1 0.33 9.1 0.0 5.1 5 1 1 6 6 6 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 EMC90252.1 - 0.00052 19.9 1.6 0.94 9.4 0.0 5.3 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 GBP_C PF02841.9 EMC90252.1 - 1.6 7.8 8.2 2.5 7.1 5.7 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RhoGEF PF00621.15 EMC90253.1 - 7.1e-42 143.3 0.6 2e-41 141.8 0.4 1.8 1 0 0 1 1 1 1 RhoGEF domain BBS2_Mid PF14783.1 EMC90253.1 - 0.017 14.8 0.1 0.32 10.7 0.0 2.5 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF3467 PF11950.3 EMC90253.1 - 0.018 15.0 0.0 2.8 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) GKAP PF03359.8 EMC90255.1 - 1.2e-148 495.4 4.2 1.2e-148 495.4 2.9 2.6 3 0 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein SOBP PF15279.1 EMC90256.1 - 5.9 7.1 13.4 9 6.5 8.7 1.5 1 1 1 2 2 2 0 Sine oculis-binding protein F-box PF00646.28 EMC90258.1 - 0.0027 17.3 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 EMC90258.1 - 0.0036 17.6 0.6 0.0099 16.2 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.2 EMC90258.1 - 0.079 12.6 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 F-box-like FAM110_C PF14160.1 EMC90259.1 - 1.1e-37 129.3 1.4 1.1e-37 129.3 1.0 2.4 3 0 0 3 3 3 1 Centrosome-associated C terminus FAM110_N PF14161.1 EMC90259.1 - 9.6e-23 80.5 0.1 2.7e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 Centrosome-associated N terminus LMWPc PF01451.16 EMC90260.1 - 4.9e-43 146.7 0.1 5.5e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FAM150 PF15129.1 EMC90261.1 - 1.4e-60 202.6 1.3 1.6e-60 202.3 0.9 1.1 1 0 0 1 1 1 1 FAM150 family TMEM18 PF14770.1 EMC90263.1 - 2.8e-44 149.6 5.6 3.1e-44 149.4 3.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 PLD_C PF12357.3 EMC90263.1 - 0.091 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D C terminal PDZ PF00595.19 EMC90264.1 - 1.3e-17 63.7 1.2 2.2e-17 63.0 0.8 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMC90264.1 - 3.6e-06 26.7 0.2 8.3e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PH PF00169.24 EMC90264.1 - 0.017 15.3 0.0 4.3 7.5 0.0 2.8 2 1 0 2 2 2 0 PH domain Tricorn_PDZ PF14685.1 EMC90264.1 - 0.023 14.4 0.4 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain An_peroxidase PF03098.10 EMC90265.1 - 9.8e-184 611.6 0.0 1.3e-183 611.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.11 EMC90265.1 - 2.7e-87 286.7 0.3 1e-20 73.3 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90265.1 - 1.7e-54 181.8 3.4 2.4e-13 50.0 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.1 EMC90265.1 - 6e-51 170.0 30.3 1.4e-17 63.1 2.3 3.8 1 1 3 4 4 4 4 Leucine rich repeat Ig_3 PF13927.1 EMC90265.1 - 9.4e-42 141.3 4.5 4.8e-11 42.9 0.3 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.20 EMC90265.1 - 3.4e-35 119.9 1.1 3.5e-12 46.2 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 EMC90265.1 - 1.2e-31 108.9 0.5 1.2e-07 31.5 0.0 5.2 4 1 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90265.1 - 5.2e-19 67.9 2.9 0.0012 18.7 0.0 4.6 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain LRR_4 PF12799.2 EMC90265.1 - 2.5e-17 62.0 16.2 1e-07 31.3 0.1 4.7 5 1 0 6 6 5 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC90265.1 - 3.2e-11 43.0 2.1 2.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) VWC PF00093.13 EMC90265.1 - 3.3e-08 33.5 18.1 3.3e-08 33.5 12.5 2.9 3 0 0 3 3 2 1 von Willebrand factor type C domain LRR_1 PF00560.28 EMC90265.1 - 1.2e-07 30.8 14.6 2.5 8.4 0.1 7.0 6 0 0 6 6 5 4 Leucine Rich Repeat Sp38 PF07354.7 EMC90265.1 - 1.4e-06 27.2 0.0 0.056 12.0 0.0 3.2 3 0 0 3 3 3 2 Zona-pellucida-binding protein (Sp38) LRR_9 PF14580.1 EMC90265.1 - 8.7e-06 25.3 0.9 0.00069 19.2 0.2 2.3 1 1 1 2 2 2 1 Leucine-rich repeat PSP94 PF05825.6 EMC90265.1 - 0.001 19.2 8.8 0.0029 17.8 6.1 1.7 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) LRR_7 PF13504.1 EMC90265.1 - 0.012 15.7 10.0 39 5.0 0.0 6.0 5 0 0 5 5 5 0 Leucine rich repeat phiKZ_IP PF12699.2 EMC90265.1 - 0.1 11.4 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins PA28_beta PF02252.13 EMC90265.1 - 0.12 11.8 0.1 0.82 9.1 0.1 2.1 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit LRR_6 PF13516.1 EMC90265.1 - 0.18 11.9 7.2 70 3.9 0.6 5.7 5 1 1 6 6 4 0 Leucine Rich repeat UPF0220 PF05255.6 EMC90265.1 - 0.38 9.9 0.0 0.68 9.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF342 PF03961.8 EMC90266.1 - 0.00059 18.3 6.3 0.00064 18.2 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DivIC PF04977.10 EMC90266.1 - 0.0014 18.0 12.8 0.038 13.4 2.1 2.4 1 1 1 2 2 2 2 Septum formation initiator TMF_DNA_bd PF12329.3 EMC90266.1 - 0.0023 17.6 14.9 0.0051 16.5 10.3 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EMC90266.1 - 0.0056 15.8 10.7 0.0056 15.8 7.4 1.6 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 EMC90266.1 - 0.0063 14.2 9.5 0.0071 14.1 6.6 1.0 1 0 0 1 1 1 1 AAA domain V_ATPase_I PF01496.14 EMC90266.1 - 0.0073 14.2 8.4 0.0083 14.0 5.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1319 PF07028.6 EMC90266.1 - 0.0089 16.2 9.3 0.04 14.1 6.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1319) CENP-Q PF13094.1 EMC90266.1 - 0.012 15.6 10.3 0.016 15.2 7.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin PF02996.12 EMC90266.1 - 0.013 15.0 4.8 0.013 15.0 3.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit Tropomyosin PF00261.15 EMC90266.1 - 0.015 14.4 10.3 0.022 13.8 7.1 1.3 1 0 0 1 1 1 0 Tropomyosin PhageMin_Tail PF10145.4 EMC90266.1 - 0.016 14.8 0.8 0.023 14.3 0.6 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein APG6 PF04111.7 EMC90266.1 - 0.021 13.9 14.5 0.019 14.0 9.6 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 EMC90266.1 - 0.023 13.8 1.7 0.025 13.7 1.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Filo_VP35 PF02097.10 EMC90266.1 - 0.032 13.4 2.4 0.048 12.8 1.7 1.2 1 0 0 1 1 1 0 Filoviridae VP35 DUF812 PF05667.6 EMC90266.1 - 0.033 12.7 12.1 0.041 12.4 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF724 PF05266.9 EMC90266.1 - 0.036 13.6 10.8 0.053 13.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 EMC90266.1 - 0.047 13.2 13.7 0.053 13.1 9.5 1.3 1 1 0 1 1 1 0 IncA protein DUF2968 PF11180.3 EMC90266.1 - 0.06 12.7 4.1 0.087 12.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GrpE PF01025.14 EMC90266.1 - 0.07 12.6 9.2 0.19 11.2 6.2 1.8 1 1 0 1 1 1 0 GrpE DUF972 PF06156.8 EMC90266.1 - 0.07 13.4 13.4 0.036 14.4 6.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EMC90266.1 - 0.083 12.6 7.2 0.09 12.5 4.1 1.8 1 1 0 2 2 1 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.6 EMC90266.1 - 0.096 10.9 8.5 0.11 10.7 5.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PspA_IM30 PF04012.7 EMC90266.1 - 0.098 12.0 8.9 0.13 11.6 6.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family Prefoldin_2 PF01920.15 EMC90266.1 - 0.11 12.3 13.8 0.74 9.6 2.5 2.4 1 1 1 2 2 2 0 Prefoldin subunit Ax_dynein_light PF10211.4 EMC90266.1 - 0.14 11.9 8.2 0.23 11.3 5.7 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain GCR PF02155.10 EMC90266.1 - 0.15 10.7 4.2 0.2 10.3 2.9 1.3 1 0 0 1 1 1 0 Glucocorticoid receptor TBPIP PF07106.8 EMC90266.1 - 0.16 11.5 15.5 0.22 11.0 9.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-H PF05837.7 EMC90266.1 - 0.17 12.0 16.0 0.073 13.2 3.2 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Peptidase_C6 PF00851.13 EMC90266.1 - 0.17 10.4 3.7 0.19 10.3 2.6 1.1 1 0 0 1 1 1 0 Helper component proteinase Tropomyosin_1 PF12718.2 EMC90266.1 - 0.19 11.5 15.2 0.27 11.0 9.7 2.0 1 1 0 1 1 1 0 Tropomyosin like Miff PF05644.6 EMC90266.1 - 0.2 11.2 6.0 0.2 11.2 3.7 1.4 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff UPF0242 PF06785.6 EMC90266.1 - 0.2 10.2 7.2 0.24 10.0 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Atg14 PF10186.4 EMC90266.1 - 0.21 10.5 8.4 0.28 10.0 5.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3251 PF11622.3 EMC90266.1 - 0.25 10.7 6.8 0.16 11.3 2.2 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3251) Mod_r PF07200.8 EMC90266.1 - 0.32 10.9 10.3 0.25 11.2 6.0 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.16 EMC90266.1 - 0.33 10.9 15.0 0.27 11.2 2.2 3.0 2 1 1 3 3 3 0 bZIP transcription factor Synaptonemal_3 PF15191.1 EMC90266.1 - 0.33 10.7 4.7 0.25 11.0 1.7 1.9 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 Nsp1_C PF05064.8 EMC90266.1 - 0.42 10.2 12.0 0.74 9.4 6.7 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region FlgN PF05130.7 EMC90266.1 - 0.44 10.7 12.4 0.25 11.5 2.6 2.1 1 1 1 2 2 2 0 FlgN protein DUF4140 PF13600.1 EMC90266.1 - 0.45 10.9 7.9 7.6 7.0 0.6 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.4 EMC90266.1 - 0.58 10.3 12.9 1.1 9.4 6.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 EMC90266.1 - 0.59 10.4 15.6 35 4.7 10.8 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Hormone_1 PF00103.15 EMC90266.1 - 0.61 9.3 6.5 0.97 8.7 4.5 1.5 1 1 0 1 1 1 0 Somatotropin hormone family RasGAP_C PF03836.10 EMC90266.1 - 0.62 9.7 10.8 2 8.1 7.4 1.9 1 1 0 1 1 1 0 RasGAP C-terminus DUF4337 PF14235.1 EMC90266.1 - 0.69 9.7 4.9 0.55 10.0 2.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3450 PF11932.3 EMC90266.1 - 0.72 9.0 11.2 1.1 8.4 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 EMC90266.1 - 1.1 9.5 9.4 56 4.0 6.5 3.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EMC90266.1 - 1.4 9.1 12.5 0.51 10.5 6.7 1.8 2 0 0 2 2 1 0 Syntaxin Pox_A_type_inc PF04508.7 EMC90266.1 - 1.5 8.8 5.2 0.83 9.5 0.1 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ATG16 PF08614.6 EMC90266.1 - 1.5 8.5 16.6 0.76 9.5 9.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2730 PF10805.3 EMC90266.1 - 1.6 8.4 6.9 8.2 6.2 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4559 PF15112.1 EMC90266.1 - 1.7 7.7 12.5 2.6 7.1 8.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Baculo_PEP_C PF04513.7 EMC90266.1 - 1.8 8.3 11.9 2.1 8.1 7.6 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GBP_C PF02841.9 EMC90266.1 - 2.1 7.4 16.4 1.8 7.6 10.7 1.3 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HALZ PF02183.13 EMC90266.1 - 2.1 8.1 7.2 4.4 7.0 1.9 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper Med4 PF10018.4 EMC90266.1 - 2.2 7.6 11.7 15 4.9 7.8 2.1 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4407 PF14362.1 EMC90266.1 - 2.4 7.0 8.1 0.73 8.7 2.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3573 PF12097.3 EMC90266.1 - 2.6 6.5 9.9 1.2 7.6 5.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF948 PF06103.6 EMC90266.1 - 3.3 7.6 8.8 1.7 8.5 2.0 2.4 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) TSC22 PF01166.13 EMC90266.1 - 3.6 7.6 17.9 0.8 9.7 1.8 2.9 3 1 1 4 4 2 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.10 EMC90266.1 - 4.5 6.3 11.3 5.1 6.2 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_CLD_2 PF14197.1 EMC90266.1 - 5.9 6.9 13.3 1.7 8.6 3.0 2.7 2 1 1 3 3 2 0 Centrosome localisation domain of PPC89 Adeno_PIX PF03955.9 EMC90266.1 - 7.3 7.1 10.2 1e+02 3.4 5.7 2.7 2 1 0 2 2 1 0 Adenovirus hexon-associated protein (IX) EMP24_GP25L PF01105.19 EMC90266.1 - 9.2 5.9 10.6 14 5.3 6.4 2.0 1 1 1 2 2 1 0 emp24/gp25L/p24 family/GOLD DASH_Dam1 PF08653.5 EMC90266.1 - 9.4 6.0 7.3 28 4.5 0.8 2.7 1 1 2 3 3 3 0 DASH complex subunit Dam1 MYT1 PF08474.6 EMC90267.1 - 1.2e-119 398.5 9.9 1.2e-119 398.5 6.8 3.5 2 1 1 3 3 3 1 Myelin transcription factor 1 zf-C2HC PF01530.13 EMC90267.1 - 2.2e-87 286.3 75.2 7.5e-17 60.7 3.2 7.5 7 0 0 7 7 7 6 Zinc finger, C2HC type zf-RING-like PF08746.6 EMC90267.1 - 0.012 15.6 18.7 4.6 7.3 0.0 6.7 6 0 0 6 6 6 0 RING-like domain zf-RAG1 PF10426.4 EMC90267.1 - 0.39 10.7 0.0 0.39 10.7 0.0 6.6 7 1 0 7 7 7 0 Recombination-activating protein 1 zinc-finger domain WD40 PF00400.27 EMC90268.1 - 3.3e-23 80.6 6.5 5e-07 29.3 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat YmzC PF14157.1 EMC90268.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.9 3 0 0 3 3 3 0 YmzC-like protein TPR_11 PF13414.1 EMC90269.1 - 1.8e-15 56.3 0.1 4.3e-07 29.4 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMC90269.1 - 1.8e-12 46.1 0.0 0.005 16.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC90269.1 - 5.3e-12 44.7 0.1 0.0011 18.4 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMC90269.1 - 5.1e-09 35.9 0.2 0.00015 21.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMC90269.1 - 7.6e-08 32.8 0.0 0.023 15.3 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC90269.1 - 2.1e-07 31.1 0.1 0.012 15.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC90269.1 - 9.6e-06 25.7 0.1 0.0043 17.4 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMC90269.1 - 5.7e-05 23.1 0.5 0.12 12.5 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EMC90269.1 - 0.00043 20.6 0.0 5.4 7.9 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMC90269.1 - 0.0012 18.4 0.0 1 9.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMC90269.1 - 0.0013 18.7 0.3 1.1 9.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EMC90269.1 - 0.0058 15.8 0.2 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_7 PF13176.1 EMC90269.1 - 0.046 13.5 0.0 3.3 7.7 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat RNase_H PF00075.19 EMC90270.1 - 4.4e-36 124.1 0.0 7e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EMC90270.1 - 0.00023 21.1 0.1 0.00068 19.6 0.1 1.9 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.1 EMC90270.1 - 0.0011 18.6 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase-like Ribosomal_S7e PF01251.13 EMC90271.1 - 3.8e-92 307.0 4.3 4.2e-92 306.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Lectin_C PF00059.16 EMC90272.1 - 5.2e-16 59.1 0.1 8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.13 EMC90272.1 - 2.4e-15 55.7 52.5 2.6e-09 36.4 17.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Thymidylate_kin PF02223.12 EMC90273.1 - 3.9e-21 75.2 0.0 1.1e-20 73.7 0.0 1.7 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 EMC90273.1 - 5.2e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMC90273.1 - 2.6e-05 24.5 0.3 0.00037 20.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMC90273.1 - 0.0027 17.7 0.0 0.0038 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EMC90273.1 - 0.003 17.5 0.1 0.0052 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMC90273.1 - 0.0033 18.2 0.0 0.0056 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain PPK2 PF03976.9 EMC90273.1 - 0.011 15.0 0.0 0.074 12.3 0.0 1.9 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) SKI PF01202.17 EMC90273.1 - 0.11 12.3 0.9 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Shikimate kinase 6PF2K PF01591.13 EMC90273.1 - 0.12 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.15 EMC90273.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase IBR PF01485.16 EMC90274.1 - 9.5e-19 67.0 27.6 1.5e-12 47.1 8.5 4.7 4 1 1 5 5 5 2 IBR domain zf-RING_2 PF13639.1 EMC90274.1 - 0.013 15.3 7.0 0.013 15.3 4.9 4.0 3 1 1 4 4 4 0 Ring finger domain HLH PF00010.21 EMC90275.1 - 6.9e-14 51.2 0.4 1.1e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain KAP_NTPase PF07693.9 EMC90276.1 - 1.4e-105 352.8 0.1 2.1e-105 352.3 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.2 EMC90276.1 - 1.7e-91 300.7 1.9 2.2e-18 66.3 0.0 5.8 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMC90276.1 - 7.5e-89 287.4 1.1 1e-09 37.7 0.0 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 EMC90276.1 - 1.1e-69 228.8 6.7 2.9e-13 49.5 0.1 10.6 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMC90276.1 - 7.9e-67 220.5 4.9 3.9e-10 39.9 0.0 9.6 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC90276.1 - 1.5e-57 185.7 1.5 1.5e-06 27.9 0.0 12.6 12 0 0 12 12 12 10 Ankyrin repeat NACHT PF05729.7 EMC90276.1 - 0.00096 18.8 0.1 0.13 11.9 0.0 3.0 3 0 0 3 3 3 1 NACHT domain SAM_1 PF00536.25 EMC90276.1 - 0.0036 17.4 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF2207 PF09972.4 EMC90276.1 - 1.9 6.9 5.6 1.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MBOAT PF03062.14 EMC90277.1 - 1.5e-33 116.2 10.4 1.5e-33 116.2 7.2 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DPM3 PF08285.6 EMC90277.1 - 0.13 12.1 2.8 0.78 9.6 1.9 2.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ArfGap PF01412.13 EMC90278.1 - 6.7e-34 116.1 0.5 2.1e-33 114.5 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EMC90278.1 - 9.9e-19 67.4 6.5 2.7e-10 40.4 0.4 2.6 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC90278.1 - 2.7e-11 42.6 0.7 0.00012 21.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.1 EMC90278.1 - 2.3e-10 39.9 0.1 4.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EMC90278.1 - 3.1e-09 36.9 0.4 1e-08 35.3 0.3 1.9 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EMC90278.1 - 6.2e-09 35.1 1.1 1.4e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 SH3 domain Ank_4 PF13637.1 EMC90278.1 - 1.2e-08 35.1 1.0 0.0002 21.7 0.0 3.0 2 1 2 4 4 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC90278.1 - 3.9e-08 33.2 0.1 1.5e-06 28.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SH3_2 PF07653.12 EMC90278.1 - 3.3e-07 29.7 0.1 8.2e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.1 EMC90278.1 - 5.9e-05 22.9 0.8 1.5 9.3 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat PH_9 PF15410.1 EMC90278.1 - 0.006 16.7 0.2 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain MIF4G PF02854.14 EMC90278.1 - 0.056 12.8 3.8 0.12 11.7 2.7 1.4 1 0 0 1 1 1 0 MIF4G domain GLTP PF08718.6 EMC90278.1 - 0.23 11.4 3.1 0.3 11.1 0.9 2.1 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) DUF4404 PF14357.1 EMC90278.1 - 3.7 8.0 8.1 1 9.8 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ICAP-1_inte_bdg PF10480.4 EMC90279.1 - 3.6e-127 421.9 8.9 3.9e-127 421.8 6.2 1.0 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.18 EMC90279.1 - 5.7e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YCII PF03795.9 EMC90279.1 - 0.048 13.8 0.0 0.088 13.0 0.0 1.6 1 1 0 1 1 1 0 YCII-related domain CPSF73-100_C PF11718.3 EMC90280.1 - 1.9e-61 207.1 0.3 3.4e-61 206.3 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EMC90280.1 - 1.9e-32 111.8 0.0 4.9e-32 110.5 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EMC90280.1 - 1.7e-15 57.2 0.3 3e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EMC90280.1 - 3.6e-13 49.1 0.0 8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EMC90280.1 - 3.3e-11 43.0 2.4 2e-10 40.5 0.6 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMC90280.1 - 9.7e-07 28.6 0.1 2.4e-05 24.1 0.0 2.9 2 1 1 3 3 3 2 Beta-lactamase superfamily domain Lipase_GDSL PF00657.17 EMC90281.1 - 7.9e-22 78.2 0.0 9.2e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMC90281.1 - 1.6e-19 70.6 0.0 2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Retrotrans_gag PF03732.12 EMC90281.1 - 0.014 15.4 0.0 0.94 9.5 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein YukD PF08817.5 EMC90281.1 - 0.076 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD 14-3-3 PF00244.15 EMC90282.1 - 2.4e-111 370.4 6.1 2.7e-111 370.2 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein PDDEXK_4 PF14281.1 EMC90282.1 - 0.036 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Clathrin-link PF09268.5 EMC90282.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker FliM PF02154.10 EMC90282.1 - 0.078 12.6 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM RRN7 PF11781.3 EMC90283.1 - 2.7e-10 39.5 4.9 2.7e-10 39.5 3.4 2.4 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 CP2 PF04516.10 EMC90284.1 - 5.9e-85 284.0 3.1 8.9e-85 283.5 2.2 1.3 1 0 0 1 1 1 1 CP2 transcription factor EF-hand_1 PF00036.27 EMC90285.1 - 3.6e-27 91.5 5.5 2.1e-07 29.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC90285.1 - 8.4e-27 93.1 1.0 2.3e-16 59.6 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC90285.1 - 5.2e-23 79.2 3.1 2.3e-07 29.8 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMC90285.1 - 1.4e-22 77.4 0.9 2.5e-06 26.8 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EMC90285.1 - 2.6e-19 68.5 4.3 1.7e-08 33.9 0.1 4.1 2 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC90285.1 - 1.4e-07 31.5 0.0 0.00034 20.6 0.0 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC90285.1 - 4e-06 26.5 0.7 0.15 11.8 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMC90285.1 - 0.008 15.8 2.3 2.8 7.6 0.0 3.2 4 0 0 4 4 4 2 EF hand Orn_Arg_deC_N PF02784.11 EMC90286.1 - 2.5e-85 285.6 0.0 3.3e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EMC90286.1 - 2.3e-33 114.3 0.1 4.6e-33 113.3 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EMC90286.1 - 0.00098 18.4 0.0 0.0023 17.2 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Cas6 PF09559.5 EMC90286.1 - 0.055 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Cas6 Crispr NUC153 PF08159.7 EMC90287.1 - 3.8e-14 51.9 1.0 8.8e-14 50.8 0.7 1.7 1 0 0 1 1 1 1 NUC153 domain Ribosomal_S16 PF00886.14 EMC90287.1 - 0.03 14.0 0.0 0.092 12.4 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S16 Thioredoxin PF00085.15 EMC90288.1 - 5.9e-67 221.9 0.0 8.4e-33 112.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EMC90288.1 - 2.4e-14 53.5 0.7 4.4e-05 23.6 0.0 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMC90288.1 - 8e-11 41.9 0.0 0.00024 21.1 0.0 3.4 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EMC90288.1 - 9.4e-10 38.5 0.0 7.8e-05 22.5 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMC90288.1 - 7e-09 35.5 0.0 0.00089 19.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 EMC90288.1 - 1.9e-05 24.3 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.16 EMC90288.1 - 0.0028 17.3 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.1 EMC90288.1 - 0.0069 16.3 0.3 1.3 8.9 0.0 3.0 2 2 2 4 4 4 1 Thioredoxin Thioredoxin_9 PF14595.1 EMC90288.1 - 0.0081 15.7 0.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 EMC90288.1 - 0.014 15.2 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE FAD_binding_7 PF03441.9 EMC90288.1 - 0.098 11.8 0.1 0.88 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase Redoxin PF08534.5 EMC90288.1 - 0.11 12.0 0.0 5 6.6 0.0 2.3 2 0 0 2 2 2 0 Redoxin Thioredoxin_5 PF13743.1 EMC90288.1 - 0.14 11.6 0.0 46 3.5 0.0 3.3 2 2 2 4 4 4 0 Thioredoxin DUF945 PF06097.6 EMC90289.1 - 0.12 11.1 0.0 0.76 8.4 0.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF945) Ion_trans PF00520.26 EMC90290.1 - 3.6e-33 114.5 5.3 3.6e-33 114.5 3.7 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC90290.1 - 2.3e-19 69.3 0.0 6.7e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC90290.1 - 1e-12 47.5 2.5 2.7e-12 46.2 1.7 1.8 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.7 EMC90290.1 - 1.7e-05 23.4 1.0 1.7e-05 23.4 0.7 1.5 1 1 0 1 1 1 1 Polycystin cation channel LLC1 PF14945.1 EMC90291.1 - 6.6e-06 26.4 4.3 5.9e-05 23.3 2.1 2.0 1 1 1 2 2 2 2 Normal lung function maintenance, Low in Lung Cancer 1 protein HD_4 PF13328.1 EMC90292.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 HD domain Pkinase PF00069.20 EMC90293.1 - 3.4e-61 206.6 0.0 3.4e-61 206.6 0.0 3.0 3 0 0 3 3 3 1 Protein kinase domain Rho_Binding PF08912.6 EMC90293.1 - 1.2e-30 105.5 14.1 1.2e-30 105.5 9.8 12.0 7 3 6 13 13 13 1 Rho Binding Pkinase_Tyr PF07714.12 EMC90293.1 - 8.2e-29 100.4 2.6 1.1e-28 100.0 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase HR1 PF02185.11 EMC90293.1 - 1.4e-09 37.5 15.3 1.4e-09 37.5 10.6 11.0 6 4 3 9 9 9 2 Hr1 repeat PH PF00169.24 EMC90293.1 - 3.6e-05 23.9 4.2 4.4e-05 23.6 0.1 2.8 2 0 0 2 2 2 1 PH domain C1_1 PF00130.17 EMC90293.1 - 0.0001 21.9 6.3 0.00023 20.8 4.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Myosin_tail_1 PF01576.14 EMC90293.1 - 0.00049 17.9 28.3 0.00049 17.9 19.6 5.0 1 1 3 4 4 4 1 Myosin tail APH PF01636.18 EMC90293.1 - 0.00082 19.1 0.3 0.004 16.9 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EMC90293.1 - 0.006 17.0 1.6 0.015 15.7 1.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain ACT_5 PF13710.1 EMC90293.1 - 0.32 10.8 5.7 0.22 11.3 1.4 2.9 2 0 0 2 2 2 0 ACT domain E2F_TDP PF02319.15 EMC90294.1 - 9e-22 76.4 0.3 2.1e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Med4 PF10018.4 EMC90294.1 - 0.0044 16.4 0.2 0.0069 15.8 0.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HrpB7 PF09486.5 EMC90294.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) YcgR_2 PF12945.2 EMC90294.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein YcgR TrmB PF01978.14 EMC90294.1 - 0.05 13.3 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Translin PF01997.11 EMC90294.1 - 0.085 12.4 0.3 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Translin family Pkinase PF00069.20 EMC90295.1 - 1e-35 123.1 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90295.1 - 6.5e-19 68.0 0.0 8.9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC90295.1 - 4.7e-06 25.7 0.0 1.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC90295.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRAT PF04970.8 EMC90296.1 - 5.7e-09 35.9 0.1 3.2e-07 30.3 0.1 2.5 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 EMC90296.1 - 0.003 17.3 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 NlpC/P60 family Nbas_N PF15492.1 EMC90297.1 - 1.7e-174 578.5 0.2 2.6e-174 577.9 0.1 1.3 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Sec39 PF08314.6 EMC90297.1 - 6.4e-126 421.0 9.8 6.4e-126 421.0 6.8 1.8 2 0 0 2 2 2 1 Secretory pathway protein Sec39 DEAD PF00270.24 EMC90298.1 - 5.8e-73 243.9 0.0 3.2e-72 241.5 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase SPRY PF00622.23 EMC90298.1 - 2.2e-25 89.1 0.1 4.3e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.26 EMC90298.1 - 2.3e-23 81.8 0.1 5.5e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EMC90298.1 - 0.0012 18.0 0.1 0.0059 15.7 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.18 EMC90298.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EMC90298.1 - 0.1 12.4 0.2 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1394 PF07159.7 EMC90299.1 - 6.2e-178 590.3 1.8 7.1e-178 590.1 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.1 EMC90299.1 - 0.0065 14.7 0.5 0.028 12.6 0.0 2.1 1 1 1 2 2 2 1 WASH complex subunit 7, N-terminal Endonuc-BglII PF09195.6 EMC90299.1 - 0.067 12.6 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease BglII EF-hand_1 PF00036.27 EMC90300.1 - 4.2e-25 85.0 13.1 2.6e-08 32.5 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EMC90300.1 - 8.5e-23 78.1 4.7 8.1e-07 28.4 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EMC90300.1 - 6.1e-22 77.5 6.3 3.5e-13 49.4 0.6 3.0 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC90300.1 - 6.8e-18 63.1 10.2 1.1e-06 27.6 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EMC90300.1 - 1.5e-15 56.4 8.9 1.6e-05 24.3 0.4 4.3 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC90300.1 - 1.8e-05 24.7 2.0 0.0042 17.1 0.3 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC90300.1 - 0.028 14.1 7.0 8.2 6.2 0.0 3.9 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EMC90300.1 - 0.031 13.8 1.9 0.45 10.0 1.3 2.7 1 1 0 1 1 1 0 Caleosin related protein p25-alpha PF05517.7 EMC90300.1 - 0.13 12.4 1.0 0.39 10.9 0.0 2.1 2 1 0 2 2 2 0 p25-alpha EF-hand_10 PF14788.1 EMC90300.1 - 0.44 10.2 5.4 14 5.4 0.0 3.6 4 0 0 4 4 4 0 EF hand SMC_N PF02463.14 EMC90301.1 - 2.5e-22 79.2 10.4 6.6e-22 77.8 7.2 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMC90301.1 - 7.6e-14 52.5 19.5 7.6e-14 52.5 13.5 6.0 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EMC90301.1 - 5e-06 26.6 11.2 0.00012 22.1 0.2 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMC90301.1 - 0.0018 17.7 0.2 0.0036 16.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EMC90301.1 - 0.014 14.5 7.6 0.19 10.8 1.4 3.2 2 1 0 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 EMC90301.1 - 0.045 13.3 98.7 0.28 10.7 8.4 6.5 2 2 3 5 5 5 0 IncA protein AAA_16 PF13191.1 EMC90301.1 - 0.06 13.3 2.7 0.26 11.2 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain WEMBL PF05701.6 EMC90301.1 - 2.1 6.6 89.1 1.3 7.4 28.6 4.1 2 2 0 2 2 2 0 Weak chloroplast movement under blue light NPV_P10 PF05531.7 EMC90301.1 - 2.5 8.3 24.8 1.8 8.8 2.7 6.3 4 2 3 7 7 7 0 Nucleopolyhedrovirus P10 protein XPG_I PF00867.13 EMC90302.1 - 2.6e-25 88.2 1.2 4.4e-25 87.5 0.1 2.0 2 0 0 2 2 2 1 XPG I-region HLH PF00010.21 EMC90304.1 - 3.7e-12 45.7 2.1 5.6e-12 45.1 0.9 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Zona_pellucida PF00100.18 EMC90305.1 - 1.6e-35 122.8 5.1 2.7e-35 122.1 0.4 2.7 2 1 1 3 3 3 1 Zona pellucida-like domain 5-nucleotidase PF06189.7 EMC90306.1 - 1.2e-103 345.5 0.0 1.3e-103 345.4 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.2 EMC90306.1 - 0.058 13.0 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Acid Phosphatase zf-C2H2 PF00096.21 EMC90307.1 - 2.6e-13 49.4 24.7 9.2e-05 22.5 2.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC90307.1 - 4.8e-13 48.6 27.7 2.6e-07 30.5 0.7 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC90307.1 - 4.8e-05 23.3 21.4 0.0046 17.1 2.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC90307.1 - 0.00032 20.4 17.2 0.0025 17.6 0.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90307.1 - 0.00069 19.6 15.5 0.021 14.9 1.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 EMC90307.1 - 0.0013 18.6 11.2 0.17 11.9 4.2 2.7 1 1 2 3 3 3 2 TFIIH C1-like domain GAGA PF09237.6 EMC90307.1 - 0.024 14.2 2.6 0.087 12.4 0.2 2.4 1 1 1 2 2 2 0 GAGA factor CpXC PF14353.1 EMC90307.1 - 0.045 13.7 7.5 0.083 12.8 0.0 2.9 1 1 2 3 3 3 0 CpXC protein zf-met PF12874.2 EMC90307.1 - 0.047 13.9 13.7 0.075 13.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2321 PF10083.4 EMC90307.1 - 0.054 12.9 1.3 0.11 12.0 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Rpr2 PF04032.11 EMC90307.1 - 0.072 12.9 0.7 0.072 12.9 0.5 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_Tnp_IS1595 PF12760.2 EMC90307.1 - 0.072 12.9 8.1 0.55 10.0 1.4 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 EMC90307.1 - 0.11 12.6 12.1 0.09 12.9 4.8 2.2 1 1 1 2 2 2 0 CHY zinc finger XPA_N PF01286.13 EMC90307.1 - 0.13 11.9 9.2 2.6 7.8 1.0 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-AN1 PF01428.11 EMC90307.1 - 0.95 9.3 17.8 2.3 8.1 3.3 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.5 EMC90307.1 - 1 9.3 11.7 7.7 6.5 0.4 3.2 2 1 0 2 2 2 0 Zinc ribbon domain LIM PF00412.17 EMC90307.1 - 1.1 9.3 12.1 9.2 6.4 4.4 2.5 1 1 0 2 2 2 0 LIM domain FYVE PF01363.16 EMC90307.1 - 1.8 8.4 15.0 0.8 9.6 5.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger Elf1 PF05129.8 EMC90307.1 - 2.2 8.0 11.2 0.34 10.6 1.3 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_5 PF14634.1 EMC90307.1 - 5.2 6.8 8.6 8.6 6.1 3.4 2.3 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.2 EMC90307.1 - 5.6 6.8 9.0 20 5.1 0.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.7 EMC90307.1 - 6.8 6.9 11.4 0.4 10.8 2.9 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zona_pellucida PF00100.18 EMC90308.1 - 1.9e-29 102.9 5.4 5.1e-28 98.2 0.1 2.9 3 0 0 3 3 3 2 Zona pellucida-like domain TPR_11 PF13414.1 EMC90309.1 - 3.1e-11 42.7 0.1 1.6e-10 40.4 0.0 2.0 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMC90309.1 - 3.1e-10 39.2 2.0 0.00028 20.3 0.0 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMC90309.1 - 8.5e-08 31.5 2.6 0.0059 16.4 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC90309.1 - 0.00011 22.1 0.0 0.0062 16.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMC90309.1 - 0.00029 20.6 0.6 0.45 10.4 0.1 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMC90309.1 - 0.00088 18.8 0.5 0.18 11.6 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMC90309.1 - 0.0038 17.8 1.5 0.22 12.2 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC90309.1 - 0.011 16.2 1.0 0.29 11.8 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC90309.1 - 0.016 15.5 0.2 0.23 11.8 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMC90309.1 - 0.022 14.0 3.4 1.2 8.4 0.0 3.0 2 1 1 3 3 3 0 SHNi-TPR Fis1_TPR_C PF14853.1 EMC90309.1 - 0.043 13.6 0.4 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 EMC90310.1 - 5.8e-11 41.8 15.1 0.012 15.4 0.0 7.1 9 0 0 9 9 9 3 WD domain, G-beta repeat Clathrin PF00637.15 EMC90310.1 - 4.1e-05 23.1 4.8 8.2e-05 22.2 1.4 2.5 1 1 1 2 2 2 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 EMC90310.1 - 4.8e-05 22.3 7.7 0.00052 18.9 0.1 4.3 5 0 0 5 5 5 1 Coatomer WD associated region eIF2A PF08662.6 EMC90310.1 - 0.0013 18.4 0.4 0.12 12.1 0.2 3.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A HMD PF03201.11 EMC90310.1 - 0.016 15.0 0.0 0.31 10.9 0.0 2.6 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase TPR_12 PF13424.1 EMC90310.1 - 0.15 11.9 6.3 12 5.8 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat VWA PF00092.23 EMC90311.1 - 9.4e-46 155.7 0.2 1.2e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.1 EMC90311.1 - 1.2e-29 102.0 62.1 1.3e-07 31.6 6.8 4.3 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 EMC90311.1 - 6.6e-21 74.0 49.9 1.9e-06 27.7 4.4 4.2 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.2 EMC90311.1 - 2.7e-19 68.4 32.0 3.1e-05 23.4 1.5 4.7 4 0 0 4 4 4 4 Complement Clr-like EGF-like VWA_2 PF13519.1 EMC90311.1 - 2.3e-17 63.6 0.0 2.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain ANATO PF01821.13 EMC90311.1 - 1e-06 28.7 18.7 0.39 10.8 1.1 5.6 4 3 0 4 4 4 4 Anaphylotoxin-like domain EGF PF00008.22 EMC90311.1 - 3.9e-06 26.6 48.9 0.098 12.6 4.7 4.4 4 0 0 4 4 4 4 EGF-like domain VWA_3 PF13768.1 EMC90311.1 - 0.00013 21.6 0.1 0.0002 21.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EMC90311.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus EGF_3 PF12947.2 EMC90311.1 - 5.7 6.9 46.1 1.4 8.9 3.4 4.8 4 0 0 4 4 4 0 EGF domain Mtp PF03821.11 EMC90312.1 - 3.8e-73 245.7 17.2 8e-71 238.1 11.9 2.0 1 1 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Sigma_reg_N PF13800.1 EMC90312.1 - 0.78 9.8 4.1 2 8.5 0.2 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal NfeD PF01957.13 EMC90312.1 - 3.2 7.8 6.2 0.69 10.0 1.1 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Ig_2 PF13895.1 EMC90313.1 - 5.4e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC90313.1 - 0.0001 22.7 0.2 0.00015 22.1 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC90313.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.8 2 1 0 2 2 2 0 Immunoglobulin domain Asp PF00026.18 EMC90314.1 - 1e-37 130.0 0.1 2.9e-37 128.5 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EMC90314.1 - 6.6e-13 48.5 0.0 9.6e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Trypsin PF00089.21 EMC90315.1 - 7.1e-70 235.0 1.4 9.8e-70 234.5 0.9 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 EMC90315.1 - 8.5e-30 102.8 0.4 1.9e-29 101.7 0.3 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 EMC90315.1 - 1.7e-08 34.0 0.0 3.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.13 EMC90315.1 - 0.00013 21.7 6.1 0.00041 20.1 4.2 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A SRCR PF00530.13 EMC90315.1 - 0.00049 20.3 0.2 0.00049 20.3 0.1 2.1 2 1 1 3 3 3 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.1 EMC90315.1 - 0.002 18.0 0.0 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf-C2H2 PF00096.21 EMC90316.1 - 5.8e-53 174.1 136.9 6.8e-06 26.1 0.9 18.0 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90316.1 - 9.9e-46 150.7 102.5 0.00018 21.6 0.3 17.4 17 0 0 17 17 17 15 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC90316.1 - 6.6e-35 117.7 111.9 3.5e-05 23.8 0.3 18.1 18 0 0 18 18 18 11 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC90316.1 - 1.2e-17 63.5 100.0 0.0029 17.7 0.1 17.5 19 0 0 19 19 19 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC90316.1 - 8.6e-17 60.7 101.3 0.0082 16.3 0.2 17.2 17 0 0 17 17 17 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC90316.1 - 7.2e-06 25.7 102.4 0.014 15.3 1.0 17.0 17 1 1 18 18 18 6 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC90316.1 - 0.0061 16.1 51.2 0.05 13.2 0.1 11.0 11 0 0 11 11 11 4 zinc-finger of a C2HC-type SET PF00856.23 EMC90316.1 - 0.0081 16.4 0.9 0.034 14.4 0.0 2.5 3 0 0 3 3 3 1 SET domain BolA PF01722.13 EMC90316.1 - 1 9.3 7.9 62 3.6 0.1 5.3 5 1 1 6 6 6 0 BolA-like protein GAGA PF09237.6 EMC90316.1 - 5 6.8 14.1 5.4 6.6 0.2 5.2 5 1 0 5 5 5 0 GAGA factor C2 PF00168.25 EMC90318.1 - 6.5e-08 32.3 0.0 4e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain DOCK-C2 PF14429.1 EMC90318.1 - 0.043 13.4 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins BTB PF00651.26 EMC90319.1 - 3.2e-26 91.4 0.1 6e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 EMC90319.1 - 1e-14 53.8 75.5 0.00087 19.4 1.2 9.3 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90319.1 - 5.4e-13 48.2 73.0 0.0046 17.1 0.1 9.5 8 1 1 9 9 9 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC90319.1 - 4.5e-06 26.6 63.1 0.0026 17.9 3.2 10.6 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC90319.1 - 0.0019 18.2 49.6 0.3 11.2 1.7 8.9 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding Desulfoferrod_N PF06397.7 EMC90319.1 - 1.3 8.5 7.5 38 3.7 0.1 4.5 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-CHCC PF10276.4 EMC90319.1 - 5.1 7.0 11.4 2.5 8.0 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger domain Actin PF00022.14 EMC90320.1 - 1.5e-88 296.8 0.0 4.4e-88 295.3 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMC90320.1 - 1.7e-05 23.6 0.0 0.032 12.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.12 EMC90320.1 - 0.013 15.0 0.1 0.034 13.6 0.0 1.6 2 0 0 2 2 2 0 Roadblock/LC7 domain Rad51 PF08423.6 EMC90321.1 - 1.2e-14 53.8 0.0 1.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMC90321.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EMC90321.1 - 0.0067 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 EMC90321.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain PID PF00640.18 EMC90323.1 - 3.1e-33 114.6 0.0 3.4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Delta_lysin PF05372.6 EMC90323.1 - 0.094 12.0 0.1 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Delta lysin family PTB PF08416.8 EMC90323.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosine-binding domain PAPS_reduct PF01507.14 EMC90324.1 - 1.1e-31 110.0 0.0 5.1e-21 75.2 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.19 EMC90324.1 - 1.2e-28 99.3 0.0 2.4e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF2559 PF10832.3 EMC90324.1 - 0.21 11.3 1.5 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) GATA PF00320.22 EMC90326.1 - 0.091 12.1 21.2 56 3.2 0.1 7.0 7 0 0 7 7 7 0 GATA zinc finger Ephrin PF00812.12 EMC90327.1 - 7e-42 142.3 2.5 7.6e-42 142.2 1.7 1.0 1 0 0 1 1 1 1 Ephrin Ephrin PF00812.12 EMC90328.1 - 1.2e-41 141.6 0.7 1.3e-41 141.5 0.5 1.0 1 0 0 1 1 1 1 Ephrin Keratin_assoc PF09775.4 EMC90329.1 - 1.7e-53 179.6 9.4 1.9e-53 179.5 6.5 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 FAM165 PF14981.1 EMC90329.1 - 0.053 13.0 0.4 1.4 8.4 0.0 2.3 2 1 0 2 2 2 0 FAM165 family DUF2069 PF09842.4 EMC90329.1 - 0.77 9.7 5.7 3.3 7.7 1.3 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2069) DUF1656 PF07869.7 EMC90329.1 - 1.3 8.8 6.8 2.8 7.7 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1656) DUF4149 PF13664.1 EMC90329.1 - 3.5 7.7 10.0 1.2 9.2 3.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Trypan_PARP PF05887.6 EMC90330.1 - 5.5 6.8 51.4 25 4.6 7.3 3.4 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) TSP_C PF05735.7 EMC90331.1 - 4.6e-77 258.1 1.7 6.5e-77 257.6 1.2 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 EMC90331.1 - 3.8e-61 202.2 133.3 1.2e-14 53.4 7.1 9.5 7 2 1 8 8 8 7 Thrombospondin type 3 repeat EGF_CA PF07645.10 EMC90331.1 - 1.6e-12 47.1 21.3 8.3e-08 32.1 1.5 5.6 5 0 0 5 5 5 2 Calcium-binding EGF domain COMP PF11598.3 EMC90331.1 - 1.6e-09 37.6 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein cEGF PF12662.2 EMC90331.1 - 7.6e-08 31.8 29.6 3.1e-05 23.5 0.7 5.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.2 EMC90331.1 - 1.5e-05 24.8 7.7 1.5e-05 24.8 5.3 6.9 4 3 1 5 5 5 3 EGF domain EGF PF00008.22 EMC90331.1 - 0.002 18.0 5.1 0.002 18.0 3.5 5.1 4 0 0 4 4 4 1 EGF-like domain Laminin_G_2 PF02210.19 EMC90331.1 - 0.022 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain EGF_MSP1_1 PF12946.2 EMC90331.1 - 0.15 11.8 18.8 0.059 13.1 3.2 3.2 2 0 0 2 2 2 0 MSP1 EGF domain 1 Tom37_C PF11801.3 EMC90332.1 - 2.2e-10 40.6 0.0 2.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain GST_C_3 PF14497.1 EMC90332.1 - 9.6e-06 26.0 0.0 1.1e-05 25.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMC90332.1 - 0.00052 19.8 0.1 0.00092 19.0 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_30 PF02055.11 EMC90333.1 - 8.2e-200 664.1 0.0 9.3e-200 664.0 0.0 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF229 PF02995.12 EMC90333.1 - 0.077 11.4 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Pkinase PF00069.20 EMC90334.1 - 3.3e-63 213.2 0.2 4.6e-63 212.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90334.1 - 2.9e-21 75.7 0.1 1.3e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase polyprenyl_synt PF00348.12 EMC90336.1 - 2.9e-75 252.4 0.0 3.7e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Erythro_esteras PF05139.9 EMC90336.1 - 0.038 13.1 0.1 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Erythromycin esterase RUN PF02759.14 EMC90337.1 - 3.8e-18 65.5 0.0 5.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.23 EMC90337.1 - 2.1e-10 39.8 0.7 5.6e-10 38.4 0.0 2.1 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EMC90337.1 - 3.2e-09 36.2 0.0 1e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC90337.1 - 4.4e-09 35.6 0.1 1.7e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain DAP3 PF10236.4 EMC90338.1 - 2.3e-90 302.6 0.0 2.7e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EMC90338.1 - 0.00041 20.3 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EMC90338.1 - 0.0012 18.3 0.0 0.0045 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMC90338.1 - 0.0013 18.4 0.0 0.0042 16.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Fmp27_SW PF10305.4 EMC90338.1 - 0.0027 18.1 0.2 0.0084 16.5 0.1 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain NACHT PF05729.7 EMC90338.1 - 0.016 14.8 0.0 0.054 13.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 EMC90338.1 - 0.018 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EMC90338.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EMC90338.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMC90338.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EMC90338.1 - 0.087 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EMC90338.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 EMC90338.1 - 0.096 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) C2 PF00168.25 EMC90339.1 - 2.2e-44 149.2 0.1 7.8e-22 76.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 EMC90339.1 - 0.003 17.0 0.1 0.66 9.4 0.0 2.5 1 1 1 2 2 2 2 CEP76 C2 domain Ras PF00071.17 EMC90340.1 - 1e-43 148.5 0.0 1.2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC90340.1 - 1e-11 45.3 0.0 1.6e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMC90340.1 - 0.00015 21.0 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC90340.1 - 0.00025 20.5 0.0 0.00032 20.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HORMA PF02301.13 EMC90341.1 - 5.3e-56 189.3 0.0 9e-56 188.6 0.0 1.4 1 0 0 1 1 1 1 HORMA domain GPP34 PF05719.6 EMC90342.1 - 1.4e-55 188.5 4.7 1.8e-55 188.2 3.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Endosulfine PF04667.12 EMC90343.1 - 4.4e-16 58.6 1.1 5e-16 58.4 0.8 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Bcl-2 PF00452.14 EMC90344.1 - 5.5e-21 74.5 0.2 7.1e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BALF1 PF06861.6 EMC90344.1 - 0.054 12.9 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 BALF1 protein Phosphorylase PF00343.15 EMC90345.1 - 3e-59 200.6 8.4 5.3e-36 123.7 1.0 3.0 2 1 1 3 3 3 3 Carbohydrate phosphorylase VASP_tetra PF08776.6 EMC90346.1 - 4.6e-13 48.2 5.9 4.6e-13 48.2 4.1 2.4 2 0 0 2 2 2 1 VASP tetramerisation domain MIP-T3 PF10243.4 EMC90346.1 - 0.17 10.3 36.5 0.006 15.1 15.2 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Cornichon PF03311.9 EMC90348.1 - 1.1e-29 103.1 4.5 2e-24 86.1 1.9 2.0 2 0 0 2 2 2 2 Cornichon protein DUF2568 PF10823.3 EMC90348.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2568) IFRD PF05004.8 EMC90348.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) WD40 PF00400.27 EMC90349.1 - 6.2e-43 143.1 3.5 8.9e-13 47.5 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC90349.1 - 2.1e-05 24.3 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 EMC90349.1 - 0.046 13.4 0.1 0.068 12.8 0.1 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain CBM_14 PF01607.19 EMC90350.1 - 0.21 11.5 1.0 0.23 11.4 0.7 1.2 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Cornichon PF03311.9 EMC90351.1 - 5e-41 139.8 1.8 5.6e-41 139.6 1.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1035 PF06281.7 EMC90351.1 - 0.095 12.5 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF2650 PF10853.3 EMC90351.1 - 0.12 11.8 0.5 0.12 11.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Lamp PF01299.12 EMC90351.1 - 0.14 11.2 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) AAA PF00004.24 EMC90352.1 - 1.1e-93 310.4 0.0 1.4e-48 164.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMC90352.1 - 2.3e-13 49.7 0.0 8.5e-06 24.9 0.0 3.0 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMC90352.1 - 3.5e-13 49.8 1.3 0.026 14.6 0.0 5.4 4 3 1 5 5 4 3 AAA domain AAA_16 PF13191.1 EMC90352.1 - 3.6e-13 49.9 2.5 5.2e-06 26.5 0.0 4.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.9 EMC90352.1 - 2.4e-12 47.1 0.0 4.1e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EMC90352.1 - 9.4e-11 42.5 0.0 0.0012 19.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMC90352.1 - 2.3e-10 40.3 1.4 9.9e-05 22.0 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMC90352.1 - 5.6e-10 39.2 0.0 0.00098 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EMC90352.1 - 6.8e-09 34.9 0.0 0.0033 16.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EMC90352.1 - 7.7e-09 34.9 0.0 0.00012 21.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 EMC90352.1 - 1e-08 35.1 0.0 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMC90352.1 - 3.5e-08 33.0 2.6 0.0077 15.9 0.3 3.1 2 1 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EMC90352.1 - 1e-07 31.3 0.2 0.0062 15.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMC90352.1 - 1.9e-07 30.7 5.4 0.074 12.4 0.0 4.4 2 2 2 4 4 4 2 AAA domain AAA_28 PF13521.1 EMC90352.1 - 5.3e-07 29.7 0.0 0.04 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMC90352.1 - 5.7e-07 29.6 0.0 0.042 14.0 0.0 3.1 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EMC90352.1 - 5.7e-07 29.1 0.2 0.034 13.5 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 EMC90352.1 - 1.2e-06 28.2 0.8 0.04 13.5 0.0 3.7 3 1 1 4 4 4 2 NACHT domain AAA_18 PF13238.1 EMC90352.1 - 1.8e-06 28.2 0.0 0.081 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EMC90352.1 - 2.8e-06 27.0 0.0 0.054 12.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EMC90352.1 - 2.3e-05 24.7 0.0 0.21 11.8 0.0 3.0 2 0 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 EMC90352.1 - 2.7e-05 24.2 0.0 0.11 12.6 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 EMC90352.1 - 3.1e-05 23.6 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EMC90352.1 - 3.5e-05 23.0 0.7 0.57 9.2 0.0 3.5 2 1 0 3 3 3 1 KaiC Sigma54_activat PF00158.21 EMC90352.1 - 0.00021 20.8 0.0 0.34 10.3 0.0 3.4 2 1 1 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.17 EMC90352.1 - 0.00029 19.7 0.0 0.47 9.2 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 EMC90352.1 - 0.00043 19.5 0.1 0.79 8.9 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein SKI PF01202.17 EMC90352.1 - 0.00085 19.2 0.0 0.47 10.3 0.0 3.0 3 0 0 3 3 2 1 Shikimate kinase Cytidylate_kin2 PF13189.1 EMC90352.1 - 0.0011 18.9 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Cytidylate kinase-like family Rad17 PF03215.10 EMC90352.1 - 0.0013 17.5 0.0 0.34 9.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 EMC90352.1 - 0.0018 17.8 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EMC90352.1 - 0.0031 17.2 0.0 6.2 6.4 0.0 3.7 2 2 1 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 EMC90352.1 - 0.0032 17.0 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EMC90352.1 - 0.0037 17.0 0.1 4.2 7.0 0.0 3.4 2 2 1 3 3 3 0 NTPase DUF815 PF05673.8 EMC90352.1 - 0.0043 16.0 0.0 0.29 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 EMC90352.1 - 0.0043 16.0 0.0 0.98 8.3 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.4 EMC90352.1 - 0.0059 16.0 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.12 EMC90352.1 - 0.0073 15.2 0.0 2.1 7.1 0.0 2.4 3 0 0 3 3 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EMC90352.1 - 0.0075 15.8 0.0 1.4 8.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EMC90352.1 - 0.03 13.9 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 EMC90352.1 - 0.069 12.0 0.0 4 6.2 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.10 EMC90352.1 - 0.094 12.5 0.0 19 5.0 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FA_desaturase PF00487.19 EMC90353.1 - 6e-24 84.8 12.6 6e-24 84.8 8.8 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 EMC90353.1 - 0.00097 18.3 0.1 0.0019 17.3 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ATG16 PF08614.6 EMC90354.1 - 0.00084 19.2 3.3 0.00084 19.2 2.3 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EMC90354.1 - 0.0033 17.0 8.3 0.0033 17.0 5.8 2.0 2 1 0 2 2 2 1 IncA protein Filament PF00038.16 EMC90354.1 - 0.012 15.0 8.4 0.026 14.0 5.8 1.4 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 EMC90354.1 - 0.013 14.1 8.6 0.027 13.1 5.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.7 EMC90354.1 - 0.031 14.6 9.5 0.031 14.6 6.6 2.9 2 1 1 3 3 3 0 SlyX TPR_MLP1_2 PF07926.7 EMC90354.1 - 0.045 13.4 10.1 0.099 12.3 7.0 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EMC90354.1 - 0.22 10.6 1.1 0.57 9.3 0.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EMC90354.1 - 0.27 10.7 9.5 0.83 9.1 5.5 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 EMC90354.1 - 0.29 10.4 6.9 0.58 9.4 4.8 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.3 EMC90354.1 - 0.4 10.4 6.3 0.77 9.5 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF3450 PF11932.3 EMC90354.1 - 0.42 9.8 10.2 0.19 10.9 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Scaffolding_pro PF11418.3 EMC90354.1 - 0.63 10.4 5.2 0.62 10.4 2.4 1.8 2 0 0 2 2 2 0 Phi29 scaffolding protein Adeno_PIX PF03955.9 EMC90354.1 - 0.92 10.0 3.8 0.78 10.2 1.1 2.1 2 1 0 2 2 1 0 Adenovirus hexon-associated protein (IX) TMF_DNA_bd PF12329.3 EMC90354.1 - 1.5 8.6 15.8 3.7 7.4 0.6 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EMC90354.1 - 1.6 9.1 11.0 1.5 9.1 4.4 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 EMC90354.1 - 2 8.1 16.0 5.7 6.6 8.4 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.6 EMC90354.1 - 2.8 7.8 8.2 4.7 7.0 2.7 2.7 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 EMC90354.1 - 2.9 8.1 10.2 10 6.4 5.7 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 EMC90354.1 - 3 7.8 5.7 10 6.2 0.1 3.5 4 0 0 4 4 2 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 EMC90354.1 - 3.6 7.9 14.3 15 6.0 9.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3287 PF11690.3 EMC90354.1 - 5.1 7.2 8.5 1.2 9.2 2.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF2458 PF10454.4 EMC90354.1 - 6 6.7 11.9 2.8 7.8 5.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) Ank PF00023.25 EMC90355.1 - 2.9e-20 70.9 0.1 1.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMC90355.1 - 6.8e-18 64.7 0.0 1.5e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC90355.1 - 1.3e-16 60.6 0.0 9.9e-12 45.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC90355.1 - 4.2e-14 51.2 0.1 1.2e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat SH3_1 PF00018.23 EMC90355.1 - 1.8e-12 46.4 1.8 3.2e-12 45.6 1.2 1.4 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.1 EMC90355.1 - 3.6e-12 46.1 1.3 7.1e-10 38.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_9 PF14604.1 EMC90355.1 - 2.5e-11 42.9 0.5 5.6e-11 41.8 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMC90355.1 - 2.5e-07 30.0 0.0 4.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_C2 PF00648.16 EMC90356.1 - 1.4e-144 480.6 0.0 2.9e-144 479.5 0.0 1.6 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMC90356.1 - 1.5e-43 147.9 0.1 3e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 EMC90356.1 - 4.3e-12 44.4 1.6 0.0097 15.1 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EMC90356.1 - 1.8e-10 40.2 5.3 7.7e-08 31.8 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC90356.1 - 1.3e-09 37.1 5.2 0.048 13.5 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EMC90356.1 - 1.6e-07 31.3 1.0 0.0048 17.0 0.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC90356.1 - 0.0032 16.7 0.2 5.4 6.5 0.0 3.8 3 0 0 3 3 3 1 EF hand Toprim PF01751.17 EMC90356.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Toprim domain Peptidase_C2 PF00648.16 EMC90357.1 - 1.1e-143 477.7 0.0 1.8e-143 476.9 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMC90357.1 - 1.3e-56 190.2 0.0 4.4e-56 188.6 0.0 1.8 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 EMC90357.1 - 3.3e-09 35.4 1.2 0.047 13.0 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EMC90357.1 - 4.5e-09 35.4 0.1 0.012 15.4 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EMC90357.1 - 7.8e-06 25.9 0.7 0.02 15.0 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMC90357.1 - 1.1e-05 24.9 6.5 0.00049 19.6 0.1 4.2 4 1 0 4 4 4 1 EF-hand domain pair Alpha_adaptin_C PF02296.11 EMC90357.1 - 0.093 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Sushi PF00084.15 EMC90358.1 - 8.2e-37 125.3 23.9 1.4e-09 38.1 0.1 4.2 4 0 0 4 4 4 4 Sushi domain (SCR repeat) cEGF PF12662.2 EMC90358.1 - 0.015 14.9 13.7 2.1 8.0 0.1 5.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like HRM PF02793.17 EMC90358.1 - 0.064 13.2 6.2 0.34 10.9 0.1 3.7 4 0 0 4 4 4 0 Hormone receptor domain LRR_8 PF13855.1 EMC90359.1 - 5.7e-47 157.3 64.0 3.1e-11 42.8 5.8 10.0 8 1 2 10 10 10 7 Leucine rich repeat TIR PF01582.15 EMC90359.1 - 1.5e-28 98.9 1.3 3e-28 98.0 0.9 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 EMC90359.1 - 3.6e-22 77.5 61.5 1.2e-07 31.1 2.9 10.4 8 2 2 11 11 11 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC90359.1 - 3.8e-17 62.1 8.4 2e-08 34.0 0.6 3.9 3 0 0 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 EMC90359.1 - 5.7e-10 37.8 67.6 0.11 12.6 0.1 16.9 18 1 0 18 18 18 6 Leucine Rich Repeat LRR_9 PF14580.1 EMC90359.1 - 6.3e-10 38.8 13.4 0.02 14.4 0.1 5.2 3 2 2 5 5 5 4 Leucine-rich repeat TIR_2 PF13676.1 EMC90359.1 - 8.4e-07 29.0 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 EMC90359.1 - 1.4e-05 24.6 55.5 0.19 11.8 0.1 14.0 13 2 3 16 16 16 3 Leucine Rich repeat LRR_7 PF13504.1 EMC90359.1 - 7.1 7.3 54.2 2.1 8.9 0.3 12.5 14 0 0 14 14 14 0 Leucine rich repeat BRO1 PF03097.13 EMC90360.1 - 5.7e-41 140.5 0.2 7.2e-41 140.1 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain Aida_C2 PF14186.1 EMC90361.1 - 2.7e-66 221.4 0.2 3.6e-66 221.0 0.1 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.5 EMC90361.1 - 8.5e-27 93.4 1.6 1.7e-26 92.4 1.1 1.5 1 0 0 1 1 1 1 Aida N-terminus NPIP PF06409.6 EMC90362.1 - 8.2e-13 47.6 23.1 3.4e-10 39.1 6.4 2.8 2 1 0 2 2 2 2 Nuclear pore complex interacting protein (NPIP) bZIP_2 PF07716.10 EMC90362.1 - 0.12 12.1 0.2 0.12 12.1 0.1 8.5 10 1 0 10 10 10 0 Basic region leucine zipper Reo_sigmaC PF04582.7 EMC90362.1 - 4.9 6.2 23.7 0.22 10.6 3.0 3.5 2 2 2 4 4 4 0 Reovirus sigma C capsid protein SH3_2 PF07653.12 EMC90363.1 - 6.9e-10 38.2 0.0 9.8e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMC90363.1 - 0.0017 17.9 0.6 0.019 14.5 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain TAF1_subA PF14929.1 EMC90364.1 - 2.7e-83 280.2 25.7 2.3e-43 148.5 3.3 3.3 1 1 2 3 3 3 3 TAF RNA Polymerase I subunit A TPR_16 PF13432.1 EMC90364.1 - 0.005 17.4 0.2 0.021 15.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMC90364.1 - 0.081 13.6 0.0 0.67 10.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMC90364.1 - 0.12 12.7 0.3 0.59 10.5 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4298 PF14131.1 EMC90364.1 - 3.3 7.6 9.6 4.1 7.3 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4298) GSDH PF07995.6 EMC90365.1 - 3e-39 135.0 0.0 4.2e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DSPc PF00782.15 EMC90366.1 - 1.3e-42 144.4 0.4 4.2e-42 142.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EMC90366.1 - 1.2e-12 48.1 0.0 1.6e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 EMC90366.1 - 6.6e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EMC90366.1 - 3.1e-05 23.4 0.1 0.00071 18.9 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EMC90366.1 - 0.0039 16.1 0.1 0.03 13.2 0.0 1.9 2 0 0 2 2 2 1 Initiator tRNA phosphoribosyl transferase I-set PF07679.11 EMC90367.1 - 5.7e-115 375.4 0.3 4.4e-15 55.3 0.0 10.6 11 0 0 11 11 11 8 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90367.1 - 1.9e-85 281.0 3.0 4.3e-11 42.7 0.0 9.6 9 0 0 9 9 9 8 Immunoglobulin domain fn3 PF00041.16 EMC90367.1 - 3.3e-77 254.6 10.6 3.5e-14 52.6 0.0 8.0 8 0 0 8 8 7 6 Fibronectin type III domain Ig_3 PF13927.1 EMC90367.1 - 2.5e-66 220.0 23.3 2.1e-10 40.9 0.0 10.7 10 0 0 10 10 9 8 Immunoglobulin domain ig PF00047.20 EMC90367.1 - 1.3e-58 194.9 4.9 5.8e-07 29.5 0.0 9.4 8 1 0 8 8 8 8 Immunoglobulin domain V-set PF07686.12 EMC90367.1 - 4.2e-40 136.1 12.2 7.5e-06 25.8 0.0 10.2 9 3 0 9 9 9 8 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90367.1 - 2.3e-15 56.2 2.9 0.18 11.7 0.0 8.7 8 0 0 8 8 8 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC90367.1 - 1.1e-06 27.2 1.6 1 7.5 0.0 6.0 4 1 2 6 6 6 2 Alphaherpesvirus glycoprotein E Interfer-bind PF09294.5 EMC90367.1 - 1.7e-06 28.0 0.8 0.3 11.1 0.0 5.1 6 0 0 6 6 5 2 Interferon-alpha/beta receptor, fibronectin type III Receptor_2B4 PF11465.3 EMC90367.1 - 8e-05 22.5 0.1 8.3 6.3 0.0 5.8 5 1 1 6 6 6 1 Natural killer cell receptor 2B4 Sp38 PF07354.7 EMC90367.1 - 0.00018 20.2 0.3 0.42 9.2 0.0 4.7 5 0 0 5 5 5 1 Zona-pellucida-binding protein (Sp38) V-set_CD47 PF08204.6 EMC90367.1 - 0.0002 21.1 1.1 1.5 8.5 0.0 5.8 7 0 0 7 7 7 1 CD47 immunoglobulin-like domain ChitinaseA_N PF08329.5 EMC90367.1 - 0.0019 17.9 0.0 0.061 13.0 0.0 3.0 2 0 0 2 2 2 1 Chitinase A, N-terminal domain DUF4446 PF14584.1 EMC90367.1 - 0.16 11.8 2.7 0.15 11.9 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) I-set PF07679.11 EMC90368.1 - 4.1e-14 52.1 0.1 2.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90368.1 - 3.3e-10 39.9 0.8 0.00023 21.2 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 EMC90368.1 - 2.7e-09 36.8 0.7 3.1e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC90368.1 - 3.9e-07 29.9 0.6 0.00016 21.5 0.0 2.4 1 1 1 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC90368.1 - 1.9e-06 28.2 4.2 0.0046 17.4 0.0 3.4 1 1 2 3 3 3 2 Immunoglobulin domain C1-set PF07654.10 EMC90368.1 - 5.4e-06 26.3 0.1 3e-05 23.9 0.0 2.3 2 1 1 3 3 2 1 Immunoglobulin C1-set domain Marek_A PF02124.10 EMC90368.1 - 2.1e-05 24.0 1.2 3.4e-05 23.4 0.9 1.3 1 0 0 1 1 1 1 Marek's disease glycoprotein A ig PF00047.20 EMC90368.1 - 0.0011 19.0 5.9 0.025 14.6 0.0 3.7 3 1 1 4 4 3 1 Immunoglobulin domain TMEM52 PF14979.1 EMC90368.1 - 0.0015 18.4 0.4 0.0026 17.6 0.3 1.5 1 0 0 1 1 1 1 Transmembrane 52 Protocadherin PF08374.6 EMC90368.1 - 0.006 16.2 1.3 0.0091 15.6 0.9 1.3 1 0 0 1 1 1 1 Protocadherin TMEM154 PF15102.1 EMC90368.1 - 0.0082 15.8 1.0 0.0082 15.8 0.7 1.6 2 0 0 2 2 2 1 TMEM154 protein family DUF1191 PF06697.7 EMC90368.1 - 0.017 13.9 0.1 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) UPF0139 PF03669.8 EMC90368.1 - 0.041 13.4 0.1 0.074 12.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Shisa PF13908.1 EMC90368.1 - 0.041 14.0 2.9 0.078 13.1 2.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator GP41 PF00517.12 EMC90368.1 - 0.044 13.3 0.5 0.066 12.7 0.3 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Orthoreo_P10 PF07204.6 EMC90368.1 - 0.045 13.4 0.5 0.09 12.5 0.4 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LRR19-TM PF15176.1 EMC90368.1 - 0.075 12.7 2.8 0.085 12.5 0.8 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PIRT PF15099.1 EMC90368.1 - 0.099 11.8 4.7 0.26 10.5 1.8 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family gpUL132 PF11359.3 EMC90368.1 - 0.19 11.0 2.3 0.31 10.3 1.6 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4389 PF14333.1 EMC90368.1 - 0.19 11.4 2.6 0.4 10.4 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) IncA PF04156.9 EMC90368.1 - 0.21 11.1 1.5 0.4 10.2 1.0 1.3 1 0 0 1 1 1 0 IncA protein Rhabdo_glycop PF00974.13 EMC90368.1 - 0.78 7.8 5.0 1.6 6.9 3.4 1.6 1 1 0 1 1 1 0 Rhabdovirus spike glycoprotein EphA2_TM PF14575.1 EMC90368.1 - 1.5 9.3 4.0 4 7.8 2.8 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Galactosyl_T PF01762.16 EMC90369.1 - 6.3e-56 189.0 0.2 7.9e-56 188.7 0.2 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EMC90369.1 - 0.0026 17.0 0.1 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Fringe-like SH3BGR PF04908.10 EMC90370.1 - 3.1e-47 158.5 0.1 4e-47 158.2 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EMC90370.1 - 0.0015 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Lebercilin PF15619.1 EMC90371.1 - 1.4e-58 197.5 32.4 1.4e-58 197.5 22.5 2.8 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease CHD5 PF04420.9 EMC90372.1 - 4.8e-45 153.0 1.0 5.3e-45 152.9 0.7 1.0 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_20 PF13942.1 EMC90372.1 - 0.07 12.6 1.8 0.097 12.2 1.2 1.2 1 0 0 1 1 1 0 YfhG lipoprotein DUF1640 PF07798.6 EMC90372.1 - 0.62 10.0 7.1 1.9 8.4 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) HMG14_17 PF01101.13 EMC90373.1 - 7.1e-15 55.4 23.8 8.2e-15 55.2 16.5 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 AIF-MLS PF14962.1 EMC90373.1 - 9.8 5.7 9.5 11 5.6 6.6 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence WD40 PF00400.27 EMC90374.1 - 4.7e-51 168.9 14.6 3.1e-08 33.1 0.1 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat Bromodomain PF00439.20 EMC90374.1 - 3.6e-35 119.7 0.1 5.2e-17 61.5 0.1 2.7 2 0 0 2 2 2 2 Bromodomain Ets PF00178.17 EMC90376.1 - 3.6e-40 135.9 2.9 7e-40 135.0 0.4 2.3 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 EMC90376.1 - 2.4e-34 116.9 1.2 4.8e-34 115.9 0.8 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ets PF00178.17 EMC90377.1 - 4.6e-40 135.6 0.8 8.3e-40 134.8 0.5 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 EMC90377.1 - 2e-26 91.5 0.0 3.7e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 EMC90377.1 - 0.0047 16.7 0.2 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC90377.1 - 0.13 12.4 0.5 0.35 11.0 0.4 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) IRK PF01007.15 EMC90378.1 - 4.1e-164 545.2 0.9 4.9e-164 545.0 0.6 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EMC90378.1 - 0.0076 15.9 9.4 0.028 14.1 6.5 2.0 1 1 0 1 1 1 1 Ion channel Pkinase PF00069.20 EMC90379.1 - 1.6e-53 181.5 0.0 2.8e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90379.1 - 3.3e-22 78.8 0.0 5.5e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PIG-P PF08510.7 EMC90380.1 - 9.9e-39 131.8 1.9 1.2e-38 131.5 1.3 1.1 1 0 0 1 1 1 1 PIG-P EI24 PF07264.6 EMC90380.1 - 0.004 16.6 3.7 0.0049 16.3 2.6 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF1469 PF07332.6 EMC90380.1 - 0.041 13.6 0.4 0.054 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Ripply PF14998.1 EMC90381.1 - 2.1e-23 82.2 0.0 2.3e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Transcription Regulator BPL_LplA_LipB PF03099.14 EMC90382.1 - 1.8e-18 66.7 0.0 3.6e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.4 EMC90382.1 - 1.5e-10 40.4 0.0 1.4e-05 24.1 0.0 2.5 1 1 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_C PF02237.12 EMC90382.1 - 1.4e-07 31.0 0.0 3.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain ABC_transp_aux PF09822.4 EMC90382.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system SIM_C PF06621.7 EMC90383.1 - 1.9e-68 231.2 11.8 3.6e-68 230.3 8.2 1.5 1 1 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.6 EMC90383.1 - 7.5e-23 80.4 1.5 1.9e-17 63.1 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EMC90383.1 - 5.3e-20 71.4 0.5 4.5e-15 55.5 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EMC90383.1 - 4.4e-17 61.8 0.0 9.1e-12 44.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 EMC90383.1 - 7.4e-05 22.3 0.5 0.00025 20.6 0.3 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EMC90383.1 - 0.00016 21.9 0.0 0.31 11.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMC90383.1 - 0.0028 17.6 0.0 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold PMP22_Claudin PF00822.15 EMC90384.1 - 2.8e-32 111.6 11.8 3.4e-32 111.3 8.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC90384.1 - 8.2e-12 45.1 11.1 1.1e-11 44.7 7.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction YtpI PF14007.1 EMC90384.1 - 0.076 12.9 1.2 2.5 8.1 0.0 2.5 1 1 1 2 2 2 0 YtpI-like protein Amastin PF07344.6 EMC90384.1 - 0.15 11.6 13.0 0.25 10.9 8.5 1.8 1 1 1 2 2 2 0 Amastin surface glycoprotein Hormone_6 PF00236.13 EMC90384.1 - 0.22 11.3 2.1 0.4 10.5 1.5 1.4 1 0 0 1 1 1 0 Glycoprotein hormone DUF872 PF05915.7 EMC90384.1 - 1.1 9.0 4.3 0.47 10.3 0.1 2.4 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) CD20 PF04103.10 EMC90384.1 - 2.1 8.2 14.1 0.69 9.8 5.0 2.9 1 1 1 2 2 2 0 CD20-like family DUF4097 PF13349.1 EMC90384.1 - 2.8 7.4 4.7 6.2 6.3 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4097) PIRT PF15099.1 EMC90384.1 - 3.5 6.8 9.9 0.055 12.6 1.3 2.1 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family CAF-1_p60_C PF15512.1 EMC90385.1 - 3.1e-57 193.9 23.7 4.3e-57 193.4 16.4 1.2 1 0 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal WD40 PF00400.27 EMC90385.1 - 1.4e-34 116.7 11.8 7.5e-09 35.1 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC90385.1 - 1.3e-05 24.9 0.9 0.0024 17.6 0.1 3.6 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EMC90385.1 - 3.8e-05 22.6 0.1 0.014 14.2 0.0 2.6 1 1 1 2 2 2 2 Coatomer WD associated region IKI3 PF04762.7 EMC90385.1 - 0.012 13.4 0.5 0.39 8.4 0.0 2.2 2 0 0 2 2 2 0 IKI3 family HATPase_c_3 PF13589.1 EMC90386.1 - 5.3e-19 68.2 1.6 5.8e-17 61.6 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.10 EMC90386.1 - 6.1e-19 67.4 3.7 2.2e-18 65.6 2.6 2.1 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c PF02518.21 EMC90386.1 - 8.2e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APG6 PF04111.7 EMC90386.1 - 0.17 10.9 27.1 0.074 12.0 4.0 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF904 PF06005.7 EMC90386.1 - 3 8.1 18.1 1.7 8.9 0.9 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Dopey_N PF04118.9 EMC90387.1 - 2.4e-103 345.1 0.3 5.4e-103 344.0 0.2 1.6 1 0 0 1 1 1 1 Dopey, N-terminal adh_short PF00106.20 EMC90388.1 - 2.6e-24 86.0 0.0 3.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC90388.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EMC90388.1 - 1.9e-06 27.0 0.1 2.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein HATPase_c PF02518.21 EMC90388.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rubis-subs-bind PF09273.6 EMC90389.1 - 9.9e-21 73.9 0.9 2e-20 73.0 0.2 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 EMC90389.1 - 1.3e-08 35.3 0.0 2.9e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 SET domain GST_N_3 PF13417.1 EMC90390.1 - 1.5e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMC90390.1 - 9.4e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMC90390.1 - 3.7e-05 23.6 0.0 8.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMC90390.1 - 0.003 17.4 0.3 0.035 14.0 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMC90390.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EntA_Immun PF08951.5 EMC90390.1 - 0.037 14.1 0.3 0.79 9.9 0.2 2.4 2 0 0 2 2 2 0 Enterocin A Immunity Calcipressin PF04847.7 EMC90391.1 - 3.2e-59 199.6 1.1 3.7e-59 199.4 0.8 1.0 1 0 0 1 1 1 1 Calcipressin ISK_Channel PF02060.10 EMC90392.1 - 3.8e-37 126.7 0.1 4.5e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Slow voltage-gated potassium channel 7tm_6 PF02949.15 EMC90392.1 - 0.026 13.3 0.2 0.029 13.2 0.1 1.0 1 0 0 1 1 1 0 7tm Odorant receptor DDE_3 PF13358.1 EMC90393.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease FAM165 PF14981.1 EMC90394.1 - 4.2e-26 90.1 6.1 5.2e-26 89.9 4.2 1.1 1 0 0 1 1 1 1 FAM165 family DUF639 PF04842.7 EMC90394.1 - 0.065 11.3 0.1 0.069 11.2 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3236 PF11576.3 EMC90394.1 - 0.076 12.4 0.1 0.09 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) SNARE_assoc PF09335.6 EMC90394.1 - 0.096 12.8 0.0 0.1 12.8 0.0 1.0 1 0 0 1 1 1 0 SNARE associated Golgi protein ISK_Channel PF02060.10 EMC90395.1 - 2.7e-11 43.1 0.1 3e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DUF2207 PF09972.4 EMC90395.1 - 0.015 13.9 0.3 0.024 13.2 0.2 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HsdM_N PF12161.3 EMC90395.1 - 0.056 13.8 0.2 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 HsdM N-terminal domain DUF4303 PF14136.1 EMC90395.1 - 0.071 12.7 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) FeoB_C PF07664.7 EMC90395.1 - 0.079 12.3 0.5 0.12 11.8 0.4 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus DUF4014 PF13198.1 EMC90395.1 - 0.085 13.2 0.6 0.12 12.8 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) DUF1180 PF06679.7 EMC90395.1 - 0.09 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) OSTbeta PF15048.1 EMC90395.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Ribosomal_S6 PF01250.12 EMC90396.1 - 2.3e-11 43.4 0.0 2.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 OSCP PF00213.13 EMC90397.1 - 4.6e-45 153.5 0.3 5.2e-45 153.3 0.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit SH3_9 PF14604.1 EMC90398.1 - 1.1e-71 236.2 10.6 3.8e-17 61.5 0.1 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.23 EMC90398.1 - 1e-64 213.7 14.0 4e-17 61.3 0.2 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 EMC90398.1 - 7.5e-58 191.8 2.4 3.2e-14 52.1 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.15 EMC90398.1 - 1.6e-44 151.9 1.6 1.6e-44 151.9 1.1 2.9 3 1 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.2 EMC90398.1 - 9.9e-31 105.5 0.0 6e-15 54.8 0.0 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 EMC90398.1 - 4.4e-18 64.9 0.0 1.1e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 EMC90398.1 - 1.4e-08 33.4 0.0 0.0034 16.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EMC90398.1 - 2e-08 34.2 0.1 0.0013 18.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMC90398.1 - 3.5e-06 26.4 0.0 0.48 10.4 0.0 3.9 3 0 0 3 3 3 1 EF-hand domain PH PF00169.24 EMC90398.1 - 1.4e-05 25.2 1.7 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 PH domain EF-hand_5 PF13202.1 EMC90398.1 - 0.0043 16.3 0.2 0.77 9.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC90398.1 - 0.01 15.4 0.0 0.26 10.9 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair DND1_DSRM PF14709.1 EMC90400.1 - 8.8e-19 67.5 0.1 2.6e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 G-patch PF01585.18 EMC90400.1 - 8.2e-17 60.7 2.9 2e-16 59.5 2.0 1.7 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.20 EMC90400.1 - 1.3e-14 54.4 0.0 3.8e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif G-patch_2 PF12656.2 EMC90400.1 - 1.2e-06 28.2 2.2 1.9e-06 27.6 0.6 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site GARS_A PF01071.14 EMC90401.1 - 6.5e-91 303.1 0.0 1.2e-90 302.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.14 EMC90401.1 - 1.2e-64 217.1 0.4 2.8e-64 216.0 0.1 1.8 2 0 0 2 2 2 1 Formyl transferase GARS_N PF02844.10 EMC90401.1 - 4.7e-39 132.8 1.5 2e-37 127.6 0.1 3.4 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EMC90401.1 - 1.3e-35 122.6 0.8 5.1e-35 120.7 0.0 2.5 4 0 0 4 4 4 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EMC90401.1 - 8.5e-31 105.9 0.8 6.4e-30 103.1 0.2 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EMC90401.1 - 1.7e-21 76.2 0.9 5.8e-21 74.5 0.6 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EMC90401.1 - 2.3e-13 50.2 0.0 7.8e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMC90401.1 - 3.7e-08 32.5 0.0 8.5e-08 31.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EMC90401.1 - 0.00017 21.4 0.0 0.00049 19.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EMC90401.1 - 0.00018 20.8 0.0 0.0005 19.4 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EMC90401.1 - 0.0026 17.2 0.1 0.009 15.5 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 EMC90401.1 - 0.0032 16.7 0.1 0.011 15.0 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 EMC90401.1 - 0.0066 15.8 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMC90401.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF1992 PF09350.5 EMC90402.1 - 1.7e-23 82.1 0.0 4.1e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.26 EMC90402.1 - 4.6e-15 55.1 0.5 1.4e-14 53.5 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain DUF3597 PF12200.3 EMC90402.1 - 0.055 13.8 0.3 0.1 12.9 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) Peptidase_C65 PF10275.4 EMC90402.1 - 0.062 12.6 3.5 5.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain NIT PF08376.5 EMC90402.1 - 0.23 10.9 0.0 0.23 10.9 0.0 2.8 3 1 0 3 3 3 0 Nitrate and nitrite sensing UPF0220 PF05255.6 EMC90403.1 - 1.7e-53 180.3 4.3 1.8e-53 180.1 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Tissue_fac PF01108.12 EMC90404.1 - 1.6e-20 72.8 0.1 2.5e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 EMC90404.1 - 3.7e-15 55.8 0.3 7.8e-15 54.8 0.2 1.5 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 EMC90404.1 - 1.3e-08 34.8 0.4 1.2e-06 28.5 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III domain WHIM3 PF15614.1 EMC90404.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 Interfer-bind PF09294.5 EMC90405.1 - 7.5e-44 148.1 7.0 5.4e-23 81.0 0.7 3.9 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 EMC90405.1 - 2.9e-36 123.4 14.2 7.1e-19 67.5 1.7 3.5 3 0 0 3 3 3 2 Tissue factor fn3 PF00041.16 EMC90405.1 - 8.7e-09 35.3 18.6 1.4e-06 28.3 0.3 4.9 4 3 0 4 4 4 2 Fibronectin type III domain Interfer-bind PF09294.5 EMC90406.1 - 1e-27 96.2 0.0 1.7e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 EMC90406.1 - 0.00028 20.9 0.9 0.00058 19.9 0.1 1.8 3 0 0 3 3 3 1 Fibronectin type III domain Interfer-bind PF09294.5 EMC90407.1 - 9.2e-20 70.6 0.1 1.2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III HLH PF00010.21 EMC90408.1 - 5e-11 42.1 0.4 5e-11 42.1 0.3 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4571 PF15137.1 EMC90409.1 - 3.5e-90 301.2 5.8 3.9e-90 301.0 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) Syja_N PF02383.13 EMC90410.1 - 3e-83 279.2 0.0 5.6e-83 278.3 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.6 EMC90410.1 - 2.4e-56 189.3 0.4 1.9e-54 183.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.18 EMC90410.1 - 1e-27 97.6 0.6 2.1e-27 96.6 0.4 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_5 PF13893.1 EMC90410.1 - 0.014 15.2 0.1 0.54 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2870 PF11069.3 EMC90411.1 - 1.1e-31 108.7 1.8 1.1e-31 108.7 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) Flavi_glycop_C PF02832.11 EMC90411.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain ubiquitin PF00240.18 EMC90411.1 - 0.095 12.1 3.1 0.29 10.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin family FAM176 PF14851.1 EMC90412.1 - 1.2e-45 154.9 0.1 1.2e-45 154.9 0.1 1.6 2 0 0 2 2 2 1 FAM176 family Gal_Lectin PF02140.13 EMC90412.1 - 1.2e-32 112.0 6.1 1.3e-17 63.8 0.5 2.4 2 0 0 2 2 2 2 Galactose binding lectin domain FAM219A PF15260.1 EMC90412.1 - 0.0086 16.4 0.4 0.018 15.3 0.3 1.5 1 0 0 1 1 1 1 Protein family FAM219A SRA1 PF07304.6 EMC90412.1 - 0.049 13.3 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Prp19_bind PF06991.6 EMC90412.1 - 0.11 11.6 3.1 0.17 11.1 2.2 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Npa1 PF11707.3 EMC90413.1 - 6.7e-79 265.2 0.8 6.7e-79 265.2 0.6 4.5 4 1 0 4 4 4 2 Ribosome 60S biogenesis N-terminal NARP1 PF12569.3 EMC90414.1 - 3.2 6.4 9.5 4.2 6.0 6.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Yippee-Mis18 PF03226.9 EMC90415.1 - 1.6e-15 56.9 0.5 1.7e-15 56.8 0.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.20 EMC90416.1 - 3.5e-63 213.1 0.0 5.7e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90416.1 - 1.7e-34 119.1 0.0 2.6e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMC90416.1 - 6.2e-11 41.7 0.0 1.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMC90416.1 - 5.5e-06 25.6 0.1 1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMC90416.1 - 6.1e-05 22.4 0.7 0.00015 21.1 0.3 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EMC90416.1 - 0.00016 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMC90416.1 - 0.049 12.9 0.2 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CTD_bind PF04818.8 EMC90417.1 - 2.3e-15 56.5 0.0 5.7e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.17 EMC90417.1 - 3.1e-09 36.3 0.0 9.7e-09 34.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC90417.1 - 4.1e-08 32.9 0.0 7.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC90417.1 - 5.2e-07 29.5 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EMC90417.1 - 0.092 12.4 83.6 0.29 10.8 24.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Sod_Cu PF00080.15 EMC90418.1 - 5.3e-46 156.2 5.8 6.4e-46 156.0 4.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PMP22_Claudin PF00822.15 EMC90419.1 - 2.4e-27 95.6 8.4 3e-27 95.3 5.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC90419.1 - 2.2e-10 40.4 7.7 3.1e-10 40.0 5.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EMC90419.1 - 0.0043 16.3 6.7 0.1 11.8 0.1 2.2 2 0 0 2 2 2 2 Clc-like SUR7 PF06687.7 EMC90419.1 - 0.17 11.4 3.1 0.23 11.0 1.8 1.5 1 1 0 1 1 1 0 SUR7/PalI family PMP22_Claudin PF00822.15 EMC90420.1 - 3.2e-29 101.7 8.3 3.8e-29 101.4 5.7 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 EMC90420.1 - 4.1e-11 42.8 3.2 4.1e-11 42.8 2.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 EMC90420.1 - 0.00024 20.7 2.9 0.00024 20.7 2.0 1.8 1 1 1 2 2 2 1 SUR7/PalI family GSG-1 PF07803.6 EMC90420.1 - 0.061 12.9 2.1 2.4 7.8 0.1 3.1 3 0 0 3 3 3 0 GSG1-like protein Colicin_V PF02674.11 EMC90420.1 - 0.45 10.3 9.3 1.7 8.4 6.5 2.1 1 1 0 1 1 1 0 Colicin V production protein Clc-like PF07062.7 EMC90420.1 - 1.4 8.1 10.1 0.12 11.6 0.3 2.5 2 1 0 2 2 2 0 Clc-like TauE PF01925.14 EMC90420.1 - 6.8 6.0 14.9 13 5.1 10.4 1.5 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE MARVEL PF01284.18 EMC90420.1 - 8 6.2 11.5 0.24 11.1 1.3 2.7 3 0 0 3 3 3 0 Membrane-associating domain ANF_receptor PF01094.23 EMC90421.1 - 2.1e-66 224.0 0.1 3.7e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 EMC90421.1 - 1.1e-53 180.9 0.1 1.8e-53 180.2 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 EMC90421.1 - 2.4e-28 97.9 1.5 1e-27 95.9 0.4 2.5 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 EMC90421.1 - 4.4e-21 75.1 0.0 7.9e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 EMC90421.1 - 3.8e-08 33.0 0.0 6.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein PGM_PMM_II PF02879.11 EMC90421.1 - 0.16 12.2 0.0 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II BTB PF00651.26 EMC90422.1 - 1.5e-24 86.0 0.5 3.6e-24 84.8 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.12 EMC90422.1 - 4.9e-16 58.8 5.2 1.4e-15 57.3 3.6 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EMC90422.1 - 1.6e-10 40.7 7.9 3.7e-10 39.6 5.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMC90422.1 - 2.7e-07 30.3 8.8 6.2e-07 29.1 6.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Med4 PF10018.4 EMC90422.1 - 0.018 14.4 0.4 0.018 14.4 0.3 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 APG6 PF04111.7 EMC90423.1 - 0.0017 17.4 9.9 0.0019 17.3 6.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 GAS PF13851.1 EMC90423.1 - 0.028 13.6 14.9 0.035 13.2 10.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 EMC90423.1 - 0.034 13.7 10.8 0.05 13.2 7.5 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Ax_dynein_light PF10211.4 EMC90423.1 - 0.037 13.8 10.0 0.05 13.4 6.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain CCDC-167 PF15188.1 EMC90423.1 - 0.058 13.3 9.4 0.09 12.7 6.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 KIX PF02172.11 EMC90423.1 - 0.061 13.3 2.4 0.11 12.6 1.4 1.6 1 1 0 1 1 1 0 KIX domain Occludin_ELL PF07303.8 EMC90423.1 - 0.083 13.6 8.4 0.54 11.0 0.5 1.9 1 1 1 2 2 2 0 Occludin homology domain DUF4559 PF15112.1 EMC90423.1 - 0.1 11.7 5.6 0.13 11.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Mnd1 PF03962.10 EMC90423.1 - 0.13 11.8 7.4 0.16 11.6 5.1 1.1 1 0 0 1 1 1 0 Mnd1 family DUF1843 PF08898.5 EMC90423.1 - 0.15 12.1 0.4 0.15 12.1 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Spc24 PF08286.6 EMC90423.1 - 0.32 10.7 8.2 0.9 9.2 5.7 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Nup88 PF10168.4 EMC90423.1 - 0.52 8.0 8.0 0.59 7.9 5.6 1.0 1 0 0 1 1 1 0 Nuclear pore component Cdc6_C PF09079.6 EMC90423.1 - 0.53 10.0 3.7 1.7 8.4 0.5 2.2 2 0 0 2 2 2 0 CDC6, C terminal V_ATPase_I PF01496.14 EMC90423.1 - 0.53 8.0 4.4 0.54 8.0 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EMC90423.1 - 0.71 10.2 10.8 1.1 9.6 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 EMC90423.1 - 0.76 8.1 8.5 0.86 7.9 5.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 EMC90423.1 - 1 9.3 9.3 1.4 8.9 6.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.3 EMC90423.1 - 1.6 8.8 11.7 0.15 12.1 1.2 2.1 1 1 1 2 2 2 0 YlqD protein TMPIT PF07851.8 EMC90423.1 - 1.8 7.5 7.1 2.2 7.2 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Takusan PF04822.8 EMC90423.1 - 1.9 8.2 8.4 3.7 7.3 5.8 1.5 1 1 0 1 1 1 0 Takusan DivIVA PF05103.8 EMC90423.1 - 2.2 8.3 12.2 6.1 6.8 1.2 2.1 1 1 1 2 2 2 0 DivIVA protein CENP-H PF05837.7 EMC90423.1 - 3 8.0 11.6 21 5.3 8.0 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF342 PF03961.8 EMC90423.1 - 3.3 6.0 7.1 3.9 5.7 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_2 PF07716.10 EMC90423.1 - 4.3 7.2 13.9 3.8 7.4 1.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EMC90423.1 - 6.9 6.7 15.7 2.3 8.2 1.7 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family Cpn60_TCP1 PF00118.19 EMC90424.1 - 4.3e-139 464.2 4.8 4.9e-139 464.0 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UCH PF00443.24 EMC90425.1 - 7.8e-50 169.4 20.3 3.6e-49 167.2 14.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMC90425.1 - 1e-21 76.7 7.5 3.7e-21 74.9 5.2 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMC90425.1 - 1.4e-17 64.0 22.8 9.2e-15 54.8 15.8 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1115 PF06544.7 EMC90426.1 - 1.1e-31 109.1 0.3 1.7e-31 108.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 EMC90426.1 - 6.3e-13 48.6 0.7 1.1e-12 47.8 0.5 1.4 1 0 0 1 1 1 1 RWD domain Methyltransf_26 PF13659.1 EMC90427.1 - 3.3e-11 43.2 0.0 6.9e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMC90427.1 - 5.4e-08 32.3 0.0 8.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMC90427.1 - 2.6e-05 23.5 0.0 4.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EMC90427.1 - 0.0004 19.9 0.0 0.00074 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMC90427.1 - 0.00055 20.2 0.0 0.0009 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMC90427.1 - 0.0033 17.8 0.0 0.0056 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMC90427.1 - 0.021 15.3 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EMC90427.1 - 0.047 14.5 0.0 0.076 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADAM_spacer1 PF05986.9 EMC90428.1 - 8.6e-33 112.6 0.1 1.3e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 EMC90428.1 - 2.4e-22 79.5 0.3 4.2e-22 78.7 0.2 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 EMC90428.1 - 1e-12 48.6 1.1 1e-12 48.6 0.8 1.9 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.14 EMC90428.1 - 2.4e-10 40.3 19.2 1.4e-09 37.8 3.3 4.3 4 0 0 4 4 3 2 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 EMC90428.1 - 7.4e-10 39.0 1.0 1.5e-09 38.0 0.7 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMC90428.1 - 1.4e-09 38.2 2.6 1.4e-09 38.2 0.5 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC90428.1 - 2.7e-08 33.6 0.8 4.5e-08 32.8 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMC90428.1 - 0.00019 21.1 0.8 0.00039 20.1 0.5 1.5 1 0 0 1 1 1 1 Matrixin DUF3285 PF11688.3 EMC90428.1 - 0.064 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Peptidase_M54 PF07998.6 EMC90428.1 - 0.07 12.8 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Toprim_Crpt PF13342.1 EMC90428.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF955 PF06114.8 EMC90428.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF1025 PF06262.6 EMC90428.1 - 0.14 11.9 0.5 0.29 10.9 0.4 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Atracotoxin PF05353.6 EMC90429.1 - 2.4 8.0 16.6 0.074 12.8 7.2 1.8 2 0 0 2 2 2 0 Delta Atracotoxin ADAM_spacer1 PF05986.9 EMC90430.1 - 1.5e-32 111.8 0.0 2.4e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 EMC90430.1 - 3.4e-21 75.7 0.0 5.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 EMC90430.1 - 9.2e-13 48.5 0.2 1.8e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.14 EMC90430.1 - 1.4e-12 47.4 58.1 2.5e-08 33.8 4.3 6.0 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_3 PF13582.1 EMC90430.1 - 1.9e-11 44.5 0.0 4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMC90430.1 - 3.2e-08 33.3 0.1 5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMC90430.1 - 4.5e-07 30.0 0.1 7.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF2668 PF10873.3 EMC90431.1 - 8.7e-78 259.8 20.2 9.5e-78 259.7 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) Shisa PF13908.1 EMC90431.1 - 1.8e-05 24.9 1.5 1.8e-05 24.9 1.1 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator GABP-alpha PF11620.3 EMC90432.1 - 4.8e-42 141.8 1.2 2.8e-41 139.3 0.7 2.2 2 0 0 2 2 2 1 GA-binding protein alpha chain Ets PF00178.17 EMC90432.1 - 2.9e-39 133.0 0.5 2.9e-39 133.0 0.3 1.7 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 EMC90432.1 - 2.4e-28 97.6 0.2 7.4e-28 96.1 0.1 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Syntaxin-18_N PF10496.4 EMC90432.1 - 0.018 14.8 0.1 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus ATP-synt_F6 PF05511.6 EMC90433.1 - 1.1e-37 127.8 0.0 1.2e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 I-set PF07679.11 EMC90434.1 - 1e-17 63.7 0.9 1.1e-09 38.0 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 EMC90434.1 - 1.5e-17 63.5 1.1 1.4e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 EMC90434.1 - 1e-15 57.5 1.3 4e-08 33.2 0.4 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC90434.1 - 3.5e-14 52.6 3.1 5.2e-09 36.0 0.8 2.2 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC90434.1 - 3.6e-11 43.3 3.9 0.00012 22.5 1.6 3.7 2 2 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 EMC90434.1 - 0.0002 19.7 2.7 0.012 13.9 0.0 2.5 1 1 2 3 3 3 2 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 EMC90434.1 - 0.0011 18.8 0.3 0.0026 17.6 0.2 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain TMEM171 PF15471.1 EMC90434.1 - 0.031 13.0 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Receptor_2B4 PF11465.3 EMC90434.1 - 0.059 13.2 0.7 11 5.9 0.0 2.9 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 DUF4307 PF14155.1 EMC90434.1 - 0.14 11.9 4.5 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) TGS PF02824.16 EMC90435.1 - 0.00014 21.5 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain DUF2469 PF10611.4 EMC90435.1 - 0.00034 20.9 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) tRNA_SAD PF07973.9 EMC90435.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain I-set PF07679.11 EMC90437.1 - 9.4e-83 272.2 0.5 1.5e-19 69.5 0.1 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90437.1 - 2.8e-49 165.1 0.1 1.4e-09 37.9 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 EMC90437.1 - 1.3e-39 134.1 0.1 7.2e-07 29.2 0.0 6.1 6 0 0 6 6 6 5 Immunoglobulin domain Ig_3 PF13927.1 EMC90437.1 - 6.3e-34 116.2 2.6 6.3e-07 29.8 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 EMC90437.1 - 2.6e-30 104.6 0.5 1.2e-05 25.1 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin V-set domain fn3 PF00041.16 EMC90437.1 - 6.6e-30 103.0 1.7 1.3e-16 60.4 0.4 2.8 2 0 0 2 2 2 2 Fibronectin type III domain C2-set_2 PF08205.7 EMC90437.1 - 8.1e-12 44.8 1.0 0.0027 17.5 0.0 5.2 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 EMC90437.1 - 2.6e-06 25.9 0.2 0.058 11.6 0.0 3.8 1 1 2 4 4 4 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 EMC90437.1 - 4.6e-05 23.2 0.3 12 5.8 0.0 5.0 5 1 0 5 5 5 1 Natural killer cell receptor 2B4 Interfer-bind PF09294.5 EMC90437.1 - 0.0017 18.3 0.3 0.36 10.9 0.0 3.1 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III BiPBP_C PF06832.7 EMC90437.1 - 0.0026 17.6 0.1 1.5 8.7 0.0 4.1 4 0 0 4 4 4 1 Penicillin-Binding Protein C-terminus Family C2-set PF05790.10 EMC90437.1 - 0.028 14.3 0.2 4.7 7.2 0.0 4.2 5 0 0 5 5 5 0 Immunoglobulin C2-set domain ig PF00047.20 EMC90440.1 - 4.9e-14 52.2 2.3 2.9e-06 27.3 0.5 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC90440.1 - 3.9e-13 49.0 0.6 1.8e-08 34.1 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90440.1 - 3.1e-11 43.2 10.7 5.7e-09 35.9 1.9 2.5 2 1 1 3 3 2 2 Immunoglobulin domain V-set PF07686.12 EMC90440.1 - 3.5e-11 42.9 3.3 2.2e-07 30.7 0.0 3.0 1 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC90440.1 - 7.7e-11 42.3 2.6 3.2e-06 27.5 0.7 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 EMC90440.1 - 8e-08 30.9 0.8 0.063 11.5 0.0 3.0 1 1 2 3 3 3 3 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 EMC90440.1 - 0.00023 20.9 0.3 0.0012 18.7 0.3 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain REJ PF02010.10 EMC90440.1 - 0.023 13.0 0.8 2.6 6.2 0.0 2.1 1 1 1 2 2 2 0 REJ domain CCSMST1 PF15013.1 EMC90440.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 CCSMST1 family DUF4118 PF13493.1 EMC90440.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Podoplanin PF05808.6 EMC90440.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Podoplanin Shisa PF13908.1 EMC90440.1 - 0.11 12.7 6.7 0.057 13.5 3.2 1.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 EMC90440.1 - 0.12 11.9 5.6 0.33 10.5 3.9 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4179 PF13786.1 EMC90440.1 - 0.17 12.1 3.6 18 5.6 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) Syndecan PF01034.15 EMC90440.1 - 0.18 11.4 0.6 0.33 10.6 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Maelstrom PF13017.1 EMC90441.1 - 1.8e-42 145.2 0.7 3.1e-42 144.4 0.5 1.3 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.5 EMC90441.1 - 2.3e-16 59.9 0.2 4.6e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EMC90441.1 - 0.0082 16.3 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box LSR PF05624.9 EMC90442.1 - 7.4e-25 86.4 32.8 1.1e-24 85.8 22.8 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.12 EMC90442.1 - 6e-05 22.9 0.1 0.0016 18.2 0.1 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain zf-H2C2_2 PF13465.1 EMC90444.1 - 1.6e-57 189.0 43.2 1.2e-08 34.7 0.6 9.3 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90444.1 - 4.4e-48 158.8 59.2 1.4e-07 31.4 0.5 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90444.1 - 4.7e-29 98.5 49.0 3e-05 24.0 1.7 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC90444.1 - 6.2e-24 83.0 54.4 0.001 18.8 0.3 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90444.1 - 2.2e-11 43.5 23.4 0.057 13.5 0.2 7.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 EMC90444.1 - 8.5e-09 34.9 21.5 0.15 11.7 0.3 7.8 8 0 0 8 8 8 2 XPA protein N-terminal C1_1 PF00130.17 EMC90444.1 - 1.7e-08 34.0 21.8 0.038 13.7 0.2 5.4 1 1 5 6 6 6 6 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EMC90444.1 - 1.3e-06 28.2 35.8 0.024 14.5 2.8 7.8 6 2 0 6 6 6 2 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 EMC90444.1 - 0.00051 19.4 30.7 2 7.9 0.1 8.1 8 0 0 8 8 8 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 EMC90444.1 - 0.0022 17.7 33.3 5.6 6.8 2.4 5.5 1 1 2 3 3 3 0 Double zinc ribbon zf-RING_3 PF14369.1 EMC90444.1 - 0.0025 17.7 25.8 3 7.9 0.1 7.7 8 0 0 8 8 8 1 zinc-finger FYDLN_acid PF09538.5 EMC90444.1 - 0.0028 18.2 14.7 15 6.2 0.3 7.0 2 1 2 5 5 5 0 Protein of unknown function (FYDLN_acid) Elf1 PF05129.8 EMC90444.1 - 0.017 14.8 17.0 1.8 8.3 0.3 4.3 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like RRN7 PF11781.3 EMC90444.1 - 0.024 14.1 23.6 0.6 9.6 0.1 7.5 8 0 0 8 8 8 0 RNA polymerase I-specific transcription initiation factor Rrn7 BolA PF01722.13 EMC90444.1 - 0.027 14.4 6.4 12 5.8 0.1 4.3 2 2 1 3 3 3 0 BolA-like protein zf-Di19 PF05605.7 EMC90444.1 - 0.043 13.9 0.1 0.043 13.9 0.0 5.8 1 1 5 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding C1_3 PF07649.7 EMC90444.1 - 0.26 11.3 22.1 9.7 6.3 0.1 6.7 7 0 0 7 7 7 0 C1-like domain C1_4 PF07975.7 EMC90444.1 - 0.4 10.7 27.6 1.3 9.0 0.7 6.0 1 1 6 7 7 7 0 TFIIH C1-like domain YhfH PF14149.1 EMC90444.1 - 0.53 10.1 30.0 7.1 6.5 0.1 7.9 8 0 0 8 8 8 0 YhfH-like protein zinc_ribbon_2 PF13240.1 EMC90444.1 - 0.53 9.8 40.2 1.3 8.6 0.3 7.2 5 3 1 6 6 6 0 zinc-ribbon domain Rpr2 PF04032.11 EMC90444.1 - 0.78 9.6 19.6 1.8 8.5 5.8 4.2 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_5 PF13909.1 EMC90444.1 - 0.83 10.0 0.1 0.83 10.0 0.0 8.7 8 3 0 8 8 8 0 C2H2-type zinc-finger domain zf-met PF12874.2 EMC90444.1 - 0.86 9.9 47.3 0.12 12.6 1.3 7.7 8 0 0 8 8 7 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.2 EMC90444.1 - 0.86 9.4 44.9 2 8.2 4.5 6.6 5 2 2 7 7 6 0 Transposase zinc-ribbon domain DUF4463 PF14703.1 EMC90444.1 - 0.91 10.0 2.9 5.1 7.6 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4463) LIM PF00412.17 EMC90444.1 - 1.3 9.1 29.0 2.6 8.1 0.3 6.0 2 2 4 6 6 6 0 LIM domain CpXC PF14353.1 EMC90444.1 - 2 8.3 24.3 12 5.8 0.7 6.7 3 2 3 7 7 7 0 CpXC protein Zn_ribbon_recom PF13408.1 EMC90444.1 - 2.4 8.4 35.5 52 4.2 0.4 6.2 1 1 3 5 5 5 0 Recombinase zinc beta ribbon domain zf-AN1 PF01428.11 EMC90444.1 - 3.5 7.5 39.9 6.6 6.6 2.1 8.1 5 2 3 8 8 8 0 AN1-like Zinc finger DUF2321 PF10083.4 EMC90444.1 - 3.6 7.0 20.1 4.5 6.7 0.2 5.6 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-LYAR PF08790.6 EMC90444.1 - 3.7 7.3 29.8 5.5 6.7 0.1 7.7 8 0 0 8 8 8 0 LYAR-type C2HC zinc finger TFIIS_C PF01096.13 EMC90444.1 - 3.8 7.2 33.7 9.4 5.9 0.1 7.6 6 2 0 6 6 6 0 Transcription factor S-II (TFIIS) HypA PF01155.14 EMC90444.1 - 4.3 7.0 23.1 8.5 6.1 1.3 4.7 1 1 4 5 5 5 0 Hydrogenase expression/synthesis hypA family Endonuclease_7 PF02945.10 EMC90444.1 - 9.1 6.0 27.2 0.17 11.6 2.5 4.2 1 1 4 5 5 5 0 Recombination endonuclease VII Ig_2 PF13895.1 EMC90445.1 - 0.00027 20.9 0.1 0.02 15.0 0.0 2.5 1 1 1 2 2 2 1 Immunoglobulin domain Shisa PF13908.1 EMC90445.1 - 0.0022 18.1 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator I-set PF07679.11 EMC90445.1 - 0.0022 17.7 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain Cytadhesin_P30 PF07271.6 EMC90445.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Cytadhesin P30/P32 ig PF00047.20 EMC90445.1 - 0.02 14.9 0.9 8 6.6 0.0 3.1 4 0 0 4 4 4 0 Immunoglobulin domain EphA2_TM PF14575.1 EMC90445.1 - 0.037 14.4 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.6 EMC90445.1 - 0.11 12.2 0.9 0.24 11.1 0.6 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 I-set PF07679.11 EMC90446.1 - 9.8e-05 22.1 0.2 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 EMC90446.1 - 0.00067 19.5 0.1 0.00098 18.9 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Cadherin_pro PF08758.6 EMC90446.1 - 0.046 13.4 0.1 0.1 12.4 0.1 1.5 1 1 0 1 1 1 0 Cadherin prodomain like DUF1958 PF09211.5 EMC90446.1 - 0.42 10.7 0.1 0.42 10.7 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1958) CXCXC PF03128.9 EMC90446.1 - 6.5 7.1 6.5 32 4.9 0.1 2.8 2 0 0 2 2 2 0 CXCXC repeat V-set PF07686.12 EMC90447.1 - 3e-26 91.5 15.2 1.3e-07 31.4 0.1 6.8 6 1 0 6 6 6 6 Immunoglobulin V-set domain Ig_2 PF13895.1 EMC90447.1 - 8.2e-23 80.3 5.9 4.3e-06 26.7 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.11 EMC90447.1 - 4.1e-21 74.6 3.4 0.00021 21.0 0.0 8.0 6 2 1 7 7 7 5 Immunoglobulin I-set domain ig PF00047.20 EMC90447.1 - 9.2e-18 64.1 12.1 0.00076 19.5 0.1 8.7 7 2 0 7 7 7 4 Immunoglobulin domain Ig_3 PF13927.1 EMC90447.1 - 9.5e-07 29.2 14.5 0.4 11.2 0.1 7.6 6 3 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 EMC90448.1 - 5.1e-55 184.2 4.7 3.1e-09 36.7 0.0 7.3 6 1 1 7 7 7 7 Immunoglobulin V-set domain I-set PF07679.11 EMC90448.1 - 2e-38 130.0 0.7 4.7e-05 23.1 0.0 10.1 7 5 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90448.1 - 6.9e-34 115.8 8.5 1.7e-05 24.8 0.0 8.0 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.20 EMC90448.1 - 6.4e-21 74.2 14.9 0.00067 19.7 0.0 11.6 10 4 0 10 10 10 7 Immunoglobulin domain Ig_3 PF13927.1 EMC90448.1 - 1.3e-19 70.4 8.5 0.095 13.2 0.0 10.7 7 5 0 7 7 7 6 Immunoglobulin domain C2-set PF05790.10 EMC90448.1 - 0.023 14.6 4.6 2.9 7.9 0.0 5.2 5 0 0 5 5 5 0 Immunoglobulin C2-set domain V-set PF07686.12 EMC90449.1 - 3.4e-08 33.3 0.6 6.2e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90449.1 - 1.8e-06 27.7 0.6 4.4e-06 26.4 0.4 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 EMC90449.1 - 4.4e-05 23.8 12.0 0.17 12.4 1.1 3.8 2 2 1 3 3 3 3 Immunoglobulin domain I-set PF07679.11 EMC90449.1 - 0.0001 22.0 0.1 0.00035 20.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90449.1 - 0.00073 19.6 3.1 0.11 12.5 0.1 3.1 2 1 1 3 3 3 1 Immunoglobulin domain Tim17 PF02466.14 EMC90450.1 - 4.8e-05 23.3 0.1 6.9e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MIT PF04212.13 EMC90450.1 - 0.037 13.8 0.2 0.058 13.2 0.2 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Bacteriocin_IIc PF10439.4 EMC90450.1 - 0.11 12.6 2.8 0.22 11.6 2.0 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Glyco_transf_90 PF05686.7 EMC90451.1 - 1.1e-114 383.2 1.6 1.4e-114 382.9 1.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EMC90451.1 - 0.032 14.4 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 BCL9 PF11502.3 EMC90452.1 - 3.5e-22 77.6 2.0 1.7e-21 75.4 1.4 2.3 1 0 0 1 1 1 1 B-cell lymphoma 9 protein His_Phos_2 PF00328.17 EMC90453.1 - 7.2e-36 124.2 0.0 9.2e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Connexin PF00029.14 EMC90454.1 - 7.9e-53 177.0 0.3 1.8e-52 175.9 0.2 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 EMC90454.1 - 1.3e-29 101.7 3.0 2.9e-29 100.6 2.1 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Adeno_E3_14_5 PF04834.7 EMC90454.1 - 0.028 14.8 0.2 0.51 10.8 0.0 2.5 2 0 0 2 2 2 0 Early E3 14.5 kDa protein Brr6_like_C_C PF10104.4 EMC90454.1 - 0.47 9.9 2.7 0.43 10.0 0.1 2.2 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain LSR PF05624.9 EMC90454.1 - 0.6 9.8 3.8 0.42 10.3 0.2 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Connexin PF00029.14 EMC90455.1 - 1.6e-52 176.0 0.2 1.6e-52 176.0 0.2 1.7 2 0 0 2 2 2 1 Connexin Connexin50 PF03509.9 EMC90455.1 - 3.6e-36 123.2 0.6 1e-35 121.8 0.4 1.8 1 0 0 1 1 1 1 Gap junction alpha-8 protein (Cx50) Connexin_CCC PF10582.4 EMC90455.1 - 3.3e-32 110.0 1.9 6.8e-32 109.0 1.3 1.5 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain 7tm_1 PF00001.16 EMC90455.1 - 0.016 14.3 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) ABA_GPCR PF12430.3 EMC90456.1 - 3.2e-62 209.1 14.1 3.2e-62 209.1 9.8 2.3 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EMC90456.1 - 5.3e-28 96.8 0.1 1.6e-27 95.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) C2-set_2 PF08205.7 EMC90457.1 - 3.4e-09 36.4 1.8 7.8e-09 35.3 1.3 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC90457.1 - 3.3e-07 30.0 0.1 0.00011 22.0 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 EMC90457.1 - 2.6e-06 27.3 1.1 2.4e-05 24.2 0.0 2.3 1 1 1 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC90457.1 - 9e-05 22.9 2.2 0.44 11.1 0.7 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC90457.1 - 0.0023 18.0 3.7 0.12 12.5 0.5 2.6 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC90457.1 - 0.011 15.8 2.9 1.5 8.9 0.0 4.0 3 1 0 3 3 3 0 Immunoglobulin domain C1-set PF07654.10 EMC90457.1 - 0.017 15.0 2.4 0.069 13.1 0.9 2.3 1 1 1 2 2 2 0 Immunoglobulin C1-set domain 7tm_1 PF00001.16 EMC90458.1 - 2e-80 269.6 10.4 2e-80 269.6 7.2 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90458.1 - 6.2e-07 28.8 19.0 1e-06 28.0 11.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC90458.1 - 0.00027 20.1 13.0 0.00027 20.1 9.0 2.4 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Pou PF00157.12 EMC90459.1 - 1.3e-36 124.1 1.6 1.8e-36 123.6 0.2 2.0 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 EMC90459.1 - 2.1e-17 62.5 1.8 2.1e-17 62.5 1.3 1.7 2 0 0 2 2 2 1 Homeobox domain Lsr2 PF11774.3 EMC90459.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 Lsr2 Snf7 PF03357.16 EMC90460.1 - 1.5e-43 148.1 28.9 1.5e-43 148.1 20.0 1.4 2 0 0 2 2 2 1 Snf7 DUF3947 PF13135.1 EMC90460.1 - 0.11 12.6 2.9 0.22 11.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) DnaJ-X PF14308.1 EMC90460.1 - 0.36 10.0 18.3 0.069 12.4 10.0 1.7 1 1 1 2 2 2 0 X-domain of DnaJ-containing CorA PF01544.13 EMC90460.1 - 0.97 8.4 7.6 9.5 5.1 5.3 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SICA_beta PF12878.2 EMC90460.1 - 1.9 8.2 13.8 3.8 7.2 9.6 1.5 1 1 0 1 1 1 0 SICA extracellular beta domain hDGE_amylase PF14701.1 EMC90460.1 - 5 5.9 11.8 8.8 5.1 8.2 1.3 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF3573 PF12097.3 EMC90460.1 - 6.4 5.2 9.1 7.9 4.9 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) CDC37_N PF03234.9 EMC90460.1 - 7.3 6.8 20.3 14 5.9 14.0 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding SOBP PF15279.1 EMC90460.1 - 8.9 6.5 9.7 11 6.3 6.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Vg_Tdu PF07545.9 EMC90461.1 - 1.6e-21 75.4 0.5 2.1e-21 75.0 0.3 1.2 1 0 0 1 1 1 1 Vestigial/Tondu family I-set PF07679.11 EMC90462.1 - 1.2e-23 82.7 0.0 9.6e-11 41.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90462.1 - 1.1e-22 79.9 0.0 9.9e-11 41.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC90462.1 - 4.3e-19 68.7 0.2 4.3e-09 36.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 EMC90462.1 - 2.7e-17 62.4 5.0 6.7e-16 57.9 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 EMC90462.1 - 2.6e-16 59.5 0.1 8.3e-08 32.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC90462.1 - 1.9e-13 50.3 0.2 0.013 15.3 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin V-set domain C1-set PF07654.10 EMC90462.1 - 2.8e-10 40.0 0.4 1.5e-09 37.6 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin C1-set domain BPD_transp_1 PF00528.17 EMC90462.1 - 0.088 12.3 1.5 0.13 11.7 1.0 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Alpha-amylase PF00128.19 EMC90464.1 - 1.6e-18 67.1 0.3 2.7e-15 56.5 0.1 2.8 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EMC90464.1 - 1e-15 57.6 0.1 3.9e-15 55.7 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 EMC90464.1 - 1.4e-14 53.8 0.1 2.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 EMC90464.1 - 0.046 12.6 0.1 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme RuBisCO_large PF00016.15 EMC90464.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Aminotran_5 PF00266.14 EMC90464.1 - 0.23 10.1 0.0 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V I-set PF07679.11 EMC90466.1 - 6.9e-72 237.3 0.0 7.6e-23 80.1 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90466.1 - 3.8e-40 135.8 0.1 1.1e-08 35.0 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.16 EMC90466.1 - 3.9e-33 113.4 10.4 2.1e-12 47.0 0.5 4.0 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.1 EMC90466.1 - 1.2e-31 108.9 1.2 5.4e-08 33.2 0.2 6.2 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.20 EMC90466.1 - 2.6e-27 94.7 0.0 6.5e-09 35.7 0.3 5.1 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 EMC90466.1 - 1.4e-25 89.4 1.0 1.2e-09 38.1 0.0 6.0 5 3 0 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90466.1 - 4.6e-09 36.0 5.4 0.039 13.8 0.0 5.7 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Big_4 PF07532.6 EMC90466.1 - 0.041 13.4 0.1 0.041 13.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 4) Receptor_2B4 PF11465.3 EMC90466.1 - 0.26 11.1 1.9 21 5.1 0.0 4.1 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 I-set PF07679.11 EMC90467.1 - 8.8e-75 246.6 0.0 4.4e-23 80.9 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90467.1 - 3.3e-47 158.4 1.1 4.5e-11 42.7 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 EMC90467.1 - 6.6e-38 129.0 1.0 1.1e-08 35.4 0.0 6.3 7 0 0 7 7 6 4 Immunoglobulin domain fn3 PF00041.16 EMC90467.1 - 1.7e-37 127.4 14.3 4.1e-15 55.6 0.7 4.4 4 0 0 4 4 4 3 Fibronectin type III domain ig PF00047.20 EMC90467.1 - 1.4e-31 108.4 0.0 2.2e-08 34.0 0.1 5.9 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 EMC90467.1 - 2.3e-29 101.6 5.1 7.2e-09 35.5 0.0 6.2 5 3 0 5 5 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90467.1 - 4.9e-07 29.5 4.2 0.47 10.3 0.0 5.7 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Sp38 PF07354.7 EMC90467.1 - 0.0024 16.5 0.0 4.3 5.9 0.0 3.7 4 0 0 4 4 4 1 Zona-pellucida-binding protein (Sp38) Receptor_2B4 PF11465.3 EMC90467.1 - 0.0078 16.1 0.7 10 6.0 0.0 4.5 3 2 1 4 4 4 1 Natural killer cell receptor 2B4 C2-set PF05790.10 EMC90467.1 - 0.037 13.9 0.3 19 5.2 0.1 3.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain RRN7 PF11781.3 EMC90467.1 - 0.52 9.8 2.6 18 4.9 0.1 3.5 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 I-set PF07679.11 EMC90468.1 - 3.2e-16 58.9 0.0 4.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90468.1 - 7e-14 51.7 0.0 8.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 EMC90468.1 - 6.2e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC90468.1 - 2.2e-05 24.4 0.1 0.00023 21.2 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 EMC90468.1 - 0.00015 21.6 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 EMC90468.1 - 0.00055 19.8 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain BiPBP_C PF06832.7 EMC90468.1 - 0.008 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family Lipase PF00151.14 EMC90469.1 - 3e-78 263.3 0.0 4.1e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 EMC90469.1 - 1.9e-05 24.7 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC90469.1 - 0.004 16.9 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EMC90469.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 EMC90469.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMC90469.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HSP70 PF00012.15 EMC90470.1 - 2e-110 369.5 0.1 3.3e-78 263.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EMC90470.1 - 1.1e-14 53.7 0.3 5.2e-11 41.7 0.0 2.8 3 0 0 3 3 3 2 MreB/Mbl protein StbA PF06406.6 EMC90470.1 - 0.013 14.5 0.0 0.025 13.5 0.0 1.5 2 0 0 2 2 2 0 StbA protein Hydantoinase_A PF01968.13 EMC90470.1 - 0.15 11.1 0.1 0.44 9.5 0.0 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EMC90470.1 - 2.3 8.0 4.5 1e+02 2.7 0.0 3.7 4 1 0 4 4 4 0 Cell division protein FtsA SLY PF12485.3 EMC90471.1 - 2.2e-52 177.4 8.9 2.2e-52 177.4 6.2 2.0 2 0 0 2 2 2 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.12 EMC90471.1 - 2.7e-09 36.7 0.2 5.7e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMC90471.1 - 2.7e-08 33.8 0.0 7.4e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EMC90471.1 - 9.2e-05 21.8 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMC90471.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 SH3 domain V-set PF07686.12 EMC90473.1 - 4.5e-20 71.6 0.7 1.2e-14 54.2 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 EMC90473.1 - 1.8e-18 66.1 0.1 2.3e-09 36.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90473.1 - 1.2e-16 60.6 1.1 6.9e-11 42.1 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC90473.1 - 3.6e-13 49.4 0.8 2.8e-07 30.5 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC90473.1 - 2.8e-12 46.9 0.9 6.1e-07 29.8 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 EMC90473.1 - 9e-05 20.9 0.2 1.1 7.4 0.0 3.2 1 1 3 4 4 4 3 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 EMC90473.1 - 0.00079 19.2 0.0 1.8 8.3 0.0 2.5 2 1 0 2 2 2 2 CD47 immunoglobulin-like domain Syndecan PF01034.15 EMC90473.1 - 0.0053 16.3 0.0 0.024 14.2 0.0 2.1 3 0 0 3 3 3 1 Syndecan domain Sp38 PF07354.7 EMC90473.1 - 0.01 14.5 0.0 0.02 13.5 0.0 1.4 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) C2-set PF05790.10 EMC90473.1 - 0.019 14.9 0.6 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin C2-set domain PAG PF15347.1 EMC90473.1 - 0.027 13.5 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched EphA2_TM PF14575.1 EMC90473.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EMC90473.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.4 EMC90473.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PetG PF02529.10 EMC90473.1 - 0.75 9.3 3.6 1.3 8.5 2.5 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 EURL PF06937.6 EMC90474.1 - 5.4e-125 416.5 1.9 6e-125 416.3 1.3 1.0 1 0 0 1 1 1 1 EURL protein TALPID3 PF15324.1 EMC90474.1 - 0.0087 13.4 1.7 0.01 13.2 1.1 1.0 1 0 0 1 1 1 1 Hedgehog signalling target FEZ PF07763.8 EMC90474.1 - 0.014 15.1 1.9 0.022 14.4 1.3 1.3 1 0 0 1 1 1 0 FEZ-like protein zf-CCHC_2 PF13696.1 EMC90474.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle XRCC4 PF06632.7 EMC90474.1 - 0.18 10.6 3.0 0.15 10.8 1.1 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 GLYCAM-1 PF05242.6 EMC90474.1 - 0.54 10.1 4.2 0.29 11.0 0.8 1.8 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Lectin_C PF00059.16 EMC90475.1 - 1.8e-13 51.0 0.3 3.6e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain Trypsin PF00089.21 EMC90476.1 - 5.2e-72 242.0 0.3 5.8e-72 241.8 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 EMC90476.1 - 5.9e-10 38.8 0.1 7.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 EMC90476.1 - 0.0005 20.0 0.0 0.00088 19.2 0.0 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S6 PF02395.11 EMC90476.1 - 0.14 10.2 0.0 0.21 9.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin A1 protease Lipase PF00151.14 EMC90477.1 - 1.4e-94 316.9 0.0 1.7e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 EMC90477.1 - 2.7e-05 24.1 1.0 3.5e-05 23.7 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC90477.1 - 0.048 13.4 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family V-set PF07686.12 EMC90478.1 - 1.3e-08 34.7 0.2 1.8e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 EMC90478.1 - 4.2e-06 27.1 1.7 0.0016 18.8 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 EMC90478.1 - 4.5e-06 26.7 0.3 0.022 14.8 0.0 2.2 1 1 1 2 2 2 2 Immunoglobulin domain I-set PF07679.11 EMC90478.1 - 4.8e-06 26.3 0.1 0.0019 17.9 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Herpes_gE PF02480.11 EMC90478.1 - 0.00029 19.2 0.0 0.00032 19.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 EMC90478.1 - 0.00077 19.3 0.2 0.36 10.7 0.0 2.3 2 0 0 2 2 2 2 Natural killer cell receptor 2B4 ig PF00047.20 EMC90478.1 - 0.0019 18.2 4.7 0.49 10.5 0.7 2.8 2 2 0 2 2 2 2 Immunoglobulin domain DUF2139 PF09910.4 EMC90478.1 - 0.0067 15.5 0.0 0.0091 15.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2139) E1-E2_ATPase PF00122.15 EMC90480.1 - 9.8e-61 204.7 1.5 1.8e-60 203.8 1.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMC90480.1 - 1.5e-44 151.6 0.4 1.5e-44 151.6 0.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMC90480.1 - 4.5e-31 108.9 0.0 5.1e-30 105.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMC90480.1 - 2e-26 91.7 0.0 7.3e-26 89.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMC90480.1 - 2e-18 65.5 0.0 4e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMC90480.1 - 5.8e-15 55.9 0.0 1.8e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMC90480.1 - 5.2e-06 26.2 1.1 0.00079 19.0 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sdh_cyt PF01127.17 EMC90480.1 - 0.0042 16.9 0.8 5.6 6.8 0.0 2.5 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2064 PF09837.4 EMC90480.1 - 0.08 12.5 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) YuiB PF14068.1 EMC90480.1 - 0.21 11.9 4.2 0.15 12.4 0.8 2.4 2 0 0 2 2 2 0 Putative membrane protein Mei5 PF10376.4 EMC90480.1 - 0.36 10.3 1.6 0.6 9.5 1.1 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein Mab-21 PF03281.9 EMC90481.1 - 1.3e-70 237.8 7.1 1.3e-70 237.8 4.9 1.3 2 0 0 2 2 2 1 Mab-21 protein PhaP_Bmeg PF09602.5 EMC90481.1 - 0.57 10.0 3.3 0.21 11.4 0.3 1.7 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) rve PF00665.21 EMC90482.1 - 1.5e-14 54.1 0.0 2.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EMC90482.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Sugar_tr PF00083.19 EMC90483.1 - 7.7e-30 103.8 17.5 1.1e-29 103.3 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMC90483.1 - 9.9e-30 103.4 47.8 4e-24 85.0 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.22 EMC90484.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Calsequestrin PF01216.12 EMC90485.1 - 1.2e-207 689.2 55.4 1.1e-206 686.0 38.4 2.1 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.1 EMC90485.1 - 7.3e-21 74.7 3.2 1.8e-18 67.0 1.7 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Nop14 PF04147.7 EMC90485.1 - 0.56 8.0 22.1 0.7 7.7 15.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMC90485.1 - 3.2 5.6 21.6 4.5 5.1 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Strabismus PF06638.6 EMC90486.1 - 1.4e-259 861.5 0.2 1.7e-259 861.2 0.1 1.0 1 0 0 1 1 1 1 Strabismus protein Virul_fac_BrkB PF03631.10 EMC90486.1 - 0.0087 15.4 7.2 0.018 14.4 4.7 1.6 2 0 0 2 2 2 1 Virulence factor BrkB SNF2_N PF00176.18 EMC90487.1 - 3.6e-68 229.5 0.1 6.3e-68 228.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC90487.1 - 2.3e-12 46.6 0.0 5.8e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMC90487.1 - 3.6e-10 39.9 0.1 2e-09 37.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMC90487.1 - 8.5e-07 28.6 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EMC90487.1 - 5.4e-06 25.4 0.0 1.9e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EMC90487.1 - 0.0012 18.9 0.8 0.0042 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMC90487.1 - 0.017 14.1 0.2 0.046 12.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TT_ORF2 PF02957.10 EMC90487.1 - 0.16 12.6 2.3 0.35 11.5 1.6 1.5 1 0 0 1 1 1 0 TT viral ORF2 Amidase PF01425.16 EMC90488.1 - 4.2e-92 309.3 0.0 5.2e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Tmp39 PF10271.4 EMC90489.1 - 9.9e-175 581.2 18.2 2.1e-174 580.1 12.6 1.5 1 1 0 1 1 1 1 Putative transmembrane protein Glyco_transf_7N PF13733.1 EMC90490.1 - 5.5e-55 184.4 0.2 9e-55 183.7 0.2 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 EMC90490.1 - 1.4e-27 94.9 0.5 3.7e-27 93.6 0.3 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC90490.1 - 4.5e-09 35.8 0.1 2.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.1 EMC90491.1 - 2.7e-50 169.2 0.2 3.9e-50 168.7 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 EMC90491.1 - 3.1e-18 65.0 0.1 5.8e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC90491.1 - 0.00081 18.5 0.0 0.41 9.6 0.0 2.7 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Glyco_transf_43 PF03360.11 EMC90492.1 - 1.8e-76 256.2 0.0 2.2e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 RhoGAP PF00620.22 EMC90493.1 - 1e-43 148.5 0.1 2.3e-43 147.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Tetraspannin PF00335.15 EMC90494.1 - 2.8e-33 115.0 9.5 7.1e-33 113.7 6.6 1.5 1 1 0 1 1 1 1 Tetraspanin family RasGEF_N PF00618.15 EMC90494.1 - 0.0041 17.2 0.1 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF N-terminal motif YrvL PF14184.1 EMC90494.1 - 1.6 8.5 11.2 0.082 12.7 3.8 1.7 2 0 0 2 2 2 0 Regulatory protein YrvL I-set PF07679.11 EMC90495.1 - 7.8e-40 134.6 2.0 6.5e-16 57.9 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90495.1 - 1.8e-31 108.1 2.3 5e-13 48.9 0.1 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 EMC90495.1 - 1.7e-21 76.4 0.7 2.5e-09 37.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 EMC90495.1 - 5.6e-20 71.2 0.2 4.3e-08 33.1 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 EMC90495.1 - 3.7e-15 55.8 2.7 0.00047 20.0 0.1 4.8 2 2 1 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90495.1 - 2.1e-07 30.7 1.6 0.011 15.6 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 EMC90495.1 - 0.00017 21.3 1.2 0.24 11.1 0.1 3.2 2 1 1 3 3 3 2 CD47 immunoglobulin-like domain C2-set PF05790.10 EMC90495.1 - 0.013 15.4 0.1 4 7.4 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Sp38 PF07354.7 EMC90495.1 - 0.031 12.9 0.2 0.1 11.2 0.0 1.9 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) BTB PF00651.26 EMC90496.1 - 3.8e-24 84.8 0.1 1.1e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 EMC90496.1 - 4.3e-22 77.2 37.7 2.1e-06 27.7 1.9 6.9 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90496.1 - 1e-21 75.8 41.3 1.9e-06 27.8 1.5 6.2 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90496.1 - 2.3e-15 55.7 32.0 0.00034 20.7 1.0 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EMC90496.1 - 2.6e-07 30.6 33.4 0.0025 17.9 1.0 5.8 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMC90496.1 - 5.8e-07 29.1 19.5 0.01 15.7 0.2 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC90496.1 - 8.8e-06 25.2 6.3 0.46 10.2 0.0 4.5 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EMC90496.1 - 0.0002 21.4 20.6 0.073 13.2 0.4 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMC90496.1 - 0.0024 17.9 24.1 0.026 14.6 6.7 4.4 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) BolA PF01722.13 EMC90496.1 - 0.021 14.7 1.4 0.91 9.5 0.2 3.4 3 1 0 3 3 3 0 BolA-like protein zf-Di19 PF05605.7 EMC90496.1 - 0.093 12.8 22.8 1.8 8.7 2.5 4.1 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.10 EMC90496.1 - 1.1 8.8 10.4 1.9 8.1 0.0 4.3 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger DUF2225 PF09986.4 EMC90496.1 - 1.5 8.2 13.0 1 8.7 0.2 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Endonuclease_7 PF02945.10 EMC90496.1 - 3.7 7.3 13.0 1.3 8.7 3.1 3.6 1 1 1 2 2 2 0 Recombination endonuclease VII 7tm_1 PF00001.16 EMC90497.1 - 8.1e-86 287.3 13.2 1.1e-85 286.8 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90497.1 - 2.1e-10 40.2 19.2 7.2e-08 31.9 10.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 EMC90497.1 - 0.38 9.8 22.9 0.007 15.5 10.8 1.8 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx TGT PF01702.13 EMC90498.1 - 8.3e-69 231.4 0.0 9.8e-69 231.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-DHHC PF01529.15 EMC90500.1 - 5.1e-36 123.6 0.9 5.1e-36 123.6 0.6 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF389 PF04087.9 EMC90500.1 - 0.048 13.6 2.2 0.26 11.2 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF389) GRAM PF02893.15 EMC90501.1 - 3.7e-19 68.0 0.2 1.3e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 GRAM domain TarH PF02203.10 EMC90501.1 - 0.031 14.1 0.3 0.062 13.1 0.2 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue V-set PF07686.12 EMC90502.1 - 2.5e-16 59.5 0.0 3.6e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 EMC90502.1 - 3.7e-08 33.1 0.0 7.9e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90502.1 - 4.5e-08 33.1 0.0 7.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 EMC90502.1 - 2.9e-06 27.3 0.0 2.4e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 EMC90502.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Ig_3 PF13927.1 EMC90502.1 - 0.00015 22.1 0.0 0.00028 21.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain DUF3872 PF12988.2 EMC90502.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) Herpes_gE PF02480.11 EMC90502.1 - 0.036 12.3 0.3 0.12 10.5 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 EMC90502.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 1 0 1 1 1 0 Natural killer cell receptor 2B4 Phospholip_A2_1 PF00068.14 EMC90503.1 - 1.8e-32 111.9 18.0 2.4e-32 111.6 12.4 1.3 1 1 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 EMC90503.1 - 0.00021 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus coat protein VP1 7tm_1 PF00001.16 EMC90504.1 - 2.4e-56 190.7 14.8 3.2e-56 190.3 10.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90504.1 - 4.5e-09 35.8 17.4 6.4e-09 35.3 12.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 EMC90504.1 - 0.00028 20.1 12.2 0.00028 20.1 8.4 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv UPF0182 PF03699.8 EMC90504.1 - 0.4 8.5 9.6 0.027 12.4 2.6 1.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0182) 60KD_IMP PF02096.15 EMC90504.1 - 1.2 8.7 6.9 0.38 10.3 2.2 2.2 1 1 0 2 2 2 0 60Kd inner membrane protein GWT1 PF06423.7 EMC90504.1 - 1.9 8.5 10.1 2.9 8.0 0.2 2.9 1 1 2 3 3 3 0 GWT1 DUF1422 PF07226.6 EMC90504.1 - 4 7.1 8.4 2.2 8.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) Apo-VLDL-II PF05418.6 EMC90505.1 - 3.3e-44 148.9 0.3 4e-44 148.6 0.2 1.1 1 0 0 1 1 1 1 Apovitellenin I (Apo-VLDL-II) Tmpp129 PF10272.4 EMC90505.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.4 1 1 0 1 1 1 0 Putative transmembrane protein precursor LSR PF05624.9 EMC90506.1 - 1.3e-19 69.6 34.5 1.9e-19 69.1 23.9 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.12 EMC90506.1 - 0.01 15.7 3.1 0.014 15.2 0.1 2.7 2 2 1 3 3 3 0 Immunoglobulin V-set domain I-set PF07679.11 EMC90506.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain WD40 PF00400.27 EMC90507.1 - 5.3e-22 76.8 0.9 2.7e-05 23.8 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EMC90507.1 - 0.027 14.7 0.1 1.2 9.4 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain Cytochrom_D1 PF02239.11 EMC90507.1 - 0.095 10.9 0.0 8.6 4.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain CENP-B_dimeris PF09026.5 EMC90508.1 - 0.19 11.9 7.5 19 5.5 4.0 2.6 2 1 0 2 2 2 0 Centromere protein B dimerisation domain DWNN PF08783.6 EMC90508.1 - 0.94 9.4 5.1 0.27 11.1 0.2 2.5 2 0 0 2 2 2 0 DWNN domain DUF4477 PF14780.1 EMC90510.1 - 2e-51 174.0 3.4 3.4e-51 173.3 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) TFIID-18kDa PF02269.11 EMC90511.1 - 5.1e-35 119.1 0.1 6.6e-35 118.7 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit GTP_EFTU_D2 PF03144.20 EMC90511.1 - 0.087 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 EMC90512.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMC90512.1 - 0.00042 20.2 0.0 0.00062 19.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase V-set PF07686.12 EMC90513.1 - 4.2e-07 29.8 1.4 8.2e-07 28.9 0.4 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90513.1 - 6.2e-06 26.0 0.2 1.4e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC90513.1 - 0.00018 21.3 0.1 0.006 16.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC90513.1 - 0.00033 21.1 5.6 0.023 15.1 0.1 3.6 2 2 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 EMC90513.1 - 0.0038 17.3 6.8 0.12 12.5 0.8 2.7 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.20 EMC90513.1 - 0.021 14.9 1.6 0.27 11.3 0.2 2.6 2 1 0 2 2 2 0 Immunoglobulin domain Rhv PF00073.15 EMC90513.1 - 0.057 13.1 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 picornavirus capsid protein V-set_CD47 PF08204.6 EMC90513.1 - 0.063 13.0 1.1 0.19 11.4 0.8 1.9 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain V-set PF07686.12 EMC90514.1 - 1.7e-07 31.0 3.3 2.3e-07 30.6 1.1 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 EMC90514.1 - 1.3e-05 25.0 0.2 4.9e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 EMC90514.1 - 0.0002 21.1 0.9 0.0036 17.1 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 EMC90514.1 - 0.0022 18.0 8.0 0.017 15.2 1.0 2.8 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 EMC90514.1 - 0.0052 17.2 10.4 0.061 13.8 0.1 3.9 3 2 0 3 3 3 1 Immunoglobulin domain PalH PF08733.5 EMC90514.1 - 0.012 14.4 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 PalH/RIM21 V-set_CD47 PF08204.6 EMC90514.1 - 0.055 13.2 3.4 0.2 11.4 2.4 2.0 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain ig PF00047.20 EMC90514.1 - 0.58 10.3 7.4 0.22 11.6 0.6 3.1 3 1 0 3 3 3 0 Immunoglobulin domain DUF4174 PF13778.1 EMC90515.1 - 4.9e-89 294.3 0.2 1.6e-34 118.5 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4174) DUF2570 PF10828.3 EMC90515.1 - 0.02 14.4 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Nuc_sug_transp PF04142.10 EMC90516.1 - 1.7e-79 266.3 7.2 2.3e-79 265.9 5.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EMC90516.1 - 1.5e-06 28.3 5.9 1.5e-06 28.3 4.1 3.2 3 0 0 3 3 3 1 EamA-like transporter family UAA PF08449.6 EMC90516.1 - 1.5e-06 27.3 13.9 3.1e-06 26.3 9.7 1.6 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EMC90516.1 - 0.0045 17.1 7.6 0.0045 17.1 5.3 3.0 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EMC90516.1 - 5.6 6.5 23.7 0.027 14.1 5.0 3.5 2 1 1 3 3 3 0 Triose-phosphate Transporter family Autophagy_N PF03986.8 EMC90517.1 - 7.1e-38 129.6 1.1 1e-37 129.1 0.5 1.5 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EMC90517.1 - 5.4e-26 90.5 4.4 1.2e-25 89.4 3.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EMC90517.1 - 7.6e-16 56.9 0.7 1.4e-15 56.0 0.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal F5_F8_type_C PF00754.20 EMC90518.1 - 1.7e-54 183.0 10.4 9.2e-30 103.1 1.4 3.2 3 0 0 3 3 3 2 F5/8 type C domain Cu-oxidase_3 PF07732.10 EMC90518.1 - 8.5e-31 106.1 0.2 1e-08 34.9 0.0 5.7 5 1 0 5 5 5 4 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMC90518.1 - 2.1e-12 46.7 5.3 0.017 14.6 0.0 6.2 5 1 0 5 5 5 4 Multicopper oxidase Folate_carrier PF01770.13 EMC90519.1 - 1.7e-161 537.3 25.4 2.1e-161 537.0 17.6 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 EMC90519.1 - 3.8e-10 39.0 18.3 3.8e-10 39.0 12.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MMPL PF03176.10 EMC90520.1 - 0.35 9.5 0.7 0.58 8.8 0.5 1.3 1 0 0 1 1 1 0 MMPL family DUF4207 PF13904.1 EMC90520.1 - 2 7.7 72.6 0.012 14.9 12.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4207) DASH_Hsk3 PF08227.6 EMC90521.1 - 2e-15 56.6 0.2 2e-15 56.6 0.2 2.4 3 0 0 3 3 3 1 DASH complex subunit Hsk3 like MbeD_MobD PF04899.7 EMC90521.1 - 0.83 9.5 10.3 0.25 11.2 0.5 3.2 1 1 2 3 3 3 0 MbeD/MobD like DivIVA PF05103.8 EMC90521.1 - 2.6 8.1 14.3 1.4 8.9 2.5 2.4 2 0 0 2 2 2 0 DivIVA protein NDK PF00334.14 EMC90522.1 - 2.1e-70 234.7 0.0 1.6e-40 138.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DERM PF14704.1 EMC90523.1 - 2.5e-40 137.8 9.8 3e-40 137.6 6.8 1.1 1 0 0 1 1 1 1 Dermatopontin IL8 PF00048.15 EMC90524.1 - 1.7e-09 37.5 0.6 2.4e-09 37.0 0.4 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like T-box PF00907.17 EMC90525.1 - 6.4e-79 263.7 0.0 8.4e-79 263.3 0.0 1.1 1 0 0 1 1 1 1 T-box Got1 PF04178.7 EMC90526.1 - 8.9e-25 87.0 14.1 1.1e-24 86.7 9.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Polysacc_synt PF01943.12 EMC90526.1 - 0.51 9.5 7.9 0.59 9.3 5.5 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YfhO PF09586.5 EMC90526.1 - 2.5 5.9 8.1 2.9 5.7 5.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2244 PF10003.4 EMC90526.1 - 7.3 5.9 14.4 0.34 10.2 3.2 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) TIP41 PF04176.8 EMC90527.1 - 2.3e-74 248.6 0.7 2.8e-74 248.3 0.5 1.1 1 0 0 1 1 1 1 TIP41-like family 7tm_1 PF00001.16 EMC90528.1 - 6.3e-46 156.5 19.8 1.1e-45 155.8 13.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EMC90528.1 - 0.0002 20.5 18.4 0.00034 19.8 12.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx EXOSC1 PF10447.4 EMC90528.1 - 0.15 12.0 0.2 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Serpentine_r_xa PF03383.10 EMC90528.1 - 2.5 7.8 11.5 0.22 11.2 1.6 2.3 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa SNF2_N PF00176.18 EMC90529.1 - 3.3e-76 255.9 0.6 5.4e-76 255.2 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMC90529.1 - 7.9e-12 44.8 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-GRF PF06839.7 EMC90529.1 - 2.9e-07 30.2 4.4 8.9e-07 28.7 0.3 2.8 2 0 0 2 2 2 1 GRF zinc finger ResIII PF04851.10 EMC90529.1 - 0.0013 18.5 0.0 0.0055 16.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Coprogen_oxidas PF01218.13 EMC90530.1 - 1.8e-120 400.9 0.0 2e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glyco_transf_29 PF00777.13 EMC90531.1 - 7.7e-72 241.6 0.0 9.6e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) TLV_coat PF00429.14 EMC90532.1 - 1.6e-13 50.0 3.9 1.8e-13 49.8 2.7 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) GP41 PF00517.12 EMC90532.1 - 0.067 12.7 1.1 0.1 12.1 0.8 1.3 1 0 0 1 1 1 0 Retroviral envelope protein MIP-T3 PF10243.4 EMC90534.1 - 0.027 12.9 109.5 0.045 12.2 75.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 EMC90534.1 - 0.13 11.4 35.8 0.16 11.1 24.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CENP-T PF15511.1 EMC90534.1 - 0.44 9.7 31.8 0.57 9.3 22.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T AvrE PF11725.3 EMC90534.1 - 4.6 4.1 29.5 5.1 3.9 20.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor Glypican PF01153.14 EMC90536.1 - 2e-209 696.8 2.1 2.2e-209 696.7 1.4 1.0 1 0 0 1 1 1 1 Glypican DSPc PF00782.15 EMC90537.1 - 8e-32 109.6 0.0 9e-32 109.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Toxin_17 PF08086.6 EMC90537.1 - 0.018 15.1 0.3 0.034 14.1 0.2 1.4 1 0 0 1 1 1 0 Ergtoxin family Y_phosphatase PF00102.22 EMC90537.1 - 0.041 13.2 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Transglut_C PF00927.17 EMC90538.1 - 6e-37 125.9 0.3 2.8e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 EMC90538.1 - 3.8e-16 59.3 0.2 8.5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Poxvirus_B22R PF04395.7 EMC90538.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein Na_sulph_symp PF00939.14 EMC90539.1 - 2.5e-98 329.9 18.2 3.5e-98 329.5 12.6 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMC90539.1 - 1.9e-13 49.7 23.2 5.9e-05 21.8 6.8 3.1 2 1 1 3 3 3 3 Citrate transporter Kdo PF06293.9 EMC90540.1 - 2.4e-09 36.5 0.0 2.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EMC90540.1 - 2.3e-05 23.7 0.0 2.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EMC90540.1 - 0.00088 19.0 0.1 0.0038 17.0 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMC90540.1 - 0.0069 15.7 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 EMC90540.1 - 0.0081 15.3 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 EMC90540.1 - 0.0099 14.9 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sugar_tr PF00083.19 EMC90541.1 - 4.3e-90 302.4 27.1 2e-66 224.4 8.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMC90541.1 - 5e-31 107.6 46.5 2.7e-22 78.9 12.3 3.1 2 1 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EMC90541.1 - 0.0037 17.0 2.2 1.1 9.0 0.2 2.8 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.8 EMC90541.1 - 0.018 13.1 15.3 0.029 12.4 2.5 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector PAS_11 PF14598.1 EMC90543.1 - 9.8e-38 128.5 0.2 3.9e-31 107.2 0.0 2.8 2 0 0 2 2 2 2 PAS domain Nuc_rec_co-act PF08815.5 EMC90543.1 - 2.1e-25 87.9 1.6 4.4e-25 86.9 1.1 1.6 1 0 0 1 1 1 1 Nuclear receptor coactivator SRC-1 PF08832.5 EMC90543.1 - 5.1e-24 84.8 5.5 5.1e-24 84.8 3.8 3.5 4 0 0 4 4 4 1 Steroid receptor coactivator PAS PF00989.19 EMC90543.1 - 3.9e-08 33.0 0.0 1.8e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EMC90543.1 - 2.3e-05 24.7 0.0 6.8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain HLH PF00010.21 EMC90543.1 - 0.0021 17.7 0.7 0.0044 16.6 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.5 EMC90543.1 - 0.17 11.9 0.0 0.57 10.2 0.0 1.9 1 0 0 1 1 1 0 PAS fold Sulfatase PF00884.18 EMC90544.1 - 2.4e-48 164.9 1.5 3.6e-48 164.3 1.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.3 EMC90544.1 - 4.2e-47 160.0 0.8 4.2e-47 160.0 0.6 2.1 2 0 0 2 2 2 1 Sulfatase protein Phosphodiest PF01663.17 EMC90544.1 - 0.00012 21.5 2.6 0.00012 21.5 1.8 1.8 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMC90544.1 - 0.045 13.1 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 Metalloenzyme superfamily Periviscerokin PF08259.6 EMC90545.1 - 3e-08 32.6 0.2 7.4e+02 0.8 0.0 11.1 13 0 0 13 13 13 0 Periviscerokinin family LRR_adjacent PF08191.6 EMC90545.1 - 0.00022 20.9 21.1 1.3e+02 2.4 0.0 11.4 1 1 12 13 13 13 0 LRR adjacent Drf_FH1 PF06346.7 EMC90545.1 - 0.0011 18.5 13.4 0.011 15.2 8.4 2.0 1 1 0 1 1 1 1 Formin Homology Region 1 DAO PF01266.19 EMC90545.1 - 0.059 12.2 7.9 0.76 8.6 1.2 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase RhoGEF PF00621.15 EMC90546.1 - 1.3e-39 135.9 0.4 1.3e-39 135.9 0.3 2.9 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.16 EMC90546.1 - 3.7e-39 132.3 0.2 5.3e-20 70.9 0.0 3.2 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.19 EMC90546.1 - 5.3e-09 36.1 0.0 0.0032 17.5 0.0 2.8 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PH PF00169.24 EMC90546.1 - 4.5e-07 30.0 0.4 3.5e-06 27.1 0.1 2.7 2 0 0 2 2 2 1 PH domain PH_10 PF15411.1 EMC90546.1 - 0.00088 19.4 0.4 0.00088 19.4 0.3 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain PDZ_2 PF13180.1 EMC90546.1 - 0.0021 17.9 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain UPF1_Zn_bind PF09416.5 EMC90546.1 - 0.019 14.5 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) DUF1580 PF07618.6 EMC90547.1 - 0.51 9.7 5.1 16 4.9 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF1580) Toxin_26 PF08097.6 EMC90547.1 - 6.8 7.3 35.9 6.4 7.4 2.1 6.6 6 0 0 6 6 6 0 Conotoxin T-superfamily CAS_CSE1 PF03378.10 EMC90548.1 - 1.2e-197 656.5 6.6 6.9e-197 654.0 3.3 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EMC90548.1 - 3e-168 559.1 5.8 6.3e-168 558.0 4.0 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EMC90548.1 - 1.2e-11 44.3 0.2 5.9e-11 42.1 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMC90548.1 - 0.00024 21.0 7.1 0.0035 17.2 0.0 4.6 2 2 2 4 4 4 1 Exportin 1-like protein PUF PF00806.14 EMC90548.1 - 0.041 13.3 0.0 1 8.9 0.0 3.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat HEAT_2 PF13646.1 EMC90548.1 - 0.14 12.4 0.2 37 4.7 0.0 3.5 2 1 1 3 3 3 0 HEAT repeats Arm PF00514.18 EMC90548.1 - 0.36 10.7 3.5 41 4.1 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TSP_1 PF00090.14 EMC90549.1 - 0.00044 20.3 2.4 0.00044 20.3 1.7 2.4 2 0 0 2 2 2 1 Thrombospondin type 1 domain Ion_trans PF00520.26 EMC90550.1 - 3.1e-36 124.4 7.9 5.3e-36 123.7 4.2 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC90550.1 - 3.1e-16 59.3 0.2 1.2e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC90550.1 - 2.2e-12 46.5 3.0 2.2e-12 46.5 2.1 2.5 3 0 0 3 3 3 1 Ion channel GLTSCR1 PF15249.1 EMC90550.1 - 0.00064 19.7 0.0 0.0042 17.1 0.0 2.2 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region PKD_channel PF08016.7 EMC90550.1 - 0.0052 15.2 1.5 0.007 14.8 0.7 1.4 1 1 0 1 1 1 1 Polycystin cation channel DUF202 PF02656.10 EMC90550.1 - 0.056 13.6 0.9 6.5 7.0 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_transf_7N PF13733.1 EMC90551.1 - 2.6e-45 153.1 0.0 3.8e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 EMC90551.1 - 2.3e-28 97.4 0.5 3.8e-28 96.7 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 EMC90551.1 - 5.6e-07 28.9 0.2 0.00023 20.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Na_H_Exchanger PF00999.16 EMC90552.1 - 6.1e-39 133.6 22.4 7.1e-39 133.4 15.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3995 PF13160.1 EMC90552.1 - 4.1 7.4 6.8 0.51 10.3 0.3 2.8 4 1 0 4 4 4 0 Protein of unknown function (DUF3995) 7tm_1 PF00001.16 EMC90554.1 - 7.1e-07 28.6 8.7 0.0002 20.6 0.1 2.0 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) PUB PF09409.5 EMC90555.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 PUB domain zf-B_box PF00643.19 EMC90555.1 - 8.3 6.3 20.9 19 5.2 5.8 3.1 2 1 0 2 2 2 0 B-box zinc finger zf-Di19 PF05605.7 EMC90556.1 - 1.2e-18 66.9 2.1 1.2e-18 66.9 1.4 3.2 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding DND1_DSRM PF14709.1 EMC90556.1 - 0.023 14.9 0.0 0.064 13.5 0.0 1.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Methyltransf_15 PF09445.5 EMC90556.1 - 0.066 12.7 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase zf-DNA_Pol PF08996.5 EMC90556.1 - 0.1 11.9 8.6 0.29 10.4 0.1 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2 PF00096.21 EMC90556.1 - 0.11 12.8 1.0 0.11 12.8 0.7 4.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-BED PF02892.10 EMC90556.1 - 0.18 11.5 0.1 0.18 11.5 0.1 3.6 3 1 1 4 4 4 0 BED zinc finger DZR PF12773.2 EMC90556.1 - 0.3 10.9 17.6 0.37 10.6 0.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.1 EMC90556.1 - 0.4 11.0 0.1 0.4 11.0 0.1 4.5 5 0 0 5 5 5 0 Zinc-finger double domain RRN7 PF11781.3 EMC90556.1 - 0.67 9.4 8.4 2.7 7.5 0.1 3.7 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 YdjO PF14169.1 EMC90556.1 - 0.76 9.2 8.5 1.2 8.6 0.0 3.8 4 0 0 4 4 4 0 Cold-inducible protein YdjO tRNA-synt_1g PF09334.6 EMC90556.1 - 1.5 7.4 4.9 5.7 5.4 3.2 1.9 1 1 1 2 2 2 0 tRNA synthetases class I (M) DUF3795 PF12675.2 EMC90556.1 - 6.9 6.9 13.9 0.31 11.2 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) zf-C2H2 PF00096.21 EMC90557.1 - 2.6e-23 80.9 37.6 9.2e-06 25.7 0.5 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC90557.1 - 1.4e-20 72.4 28.9 3.9e-08 33.2 0.2 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC90557.1 - 2.5e-13 49.3 34.1 0.0015 18.7 0.5 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90557.1 - 2.7e-13 49.6 22.4 0.00037 20.5 0.7 5.3 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC90557.1 - 2.2e-09 36.9 35.6 0.00082 19.1 0.2 5.4 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EMC90557.1 - 2.1e-07 30.9 18.4 0.0074 16.4 0.7 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMC90557.1 - 0.00013 22.0 18.3 0.054 13.6 1.0 3.5 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 EMC90557.1 - 0.0036 17.0 31.3 0.38 10.5 1.8 5.2 2 2 3 5 5 5 3 BED zinc finger Zn-ribbon_8 PF09723.5 EMC90557.1 - 0.01 15.8 23.9 0.74 9.8 0.5 4.8 4 1 0 4 4 4 2 Zinc ribbon domain zf-C2H2_2 PF12756.2 EMC90557.1 - 0.013 15.5 23.3 1.1 9.3 0.9 4.9 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Rpr2 PF04032.11 EMC90557.1 - 0.013 15.3 15.9 0.033 14.0 0.6 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HC_2 PF13913.1 EMC90557.1 - 0.013 15.1 12.1 0.37 10.4 0.4 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 EMC90557.1 - 0.74 10.0 24.6 0.14 12.3 2.8 2.5 2 1 0 2 2 2 0 CHY zinc finger PyrI_C PF02748.10 EMC90557.1 - 1.2 8.5 15.7 0.67 9.4 0.7 4.3 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.11 EMC90557.1 - 1.9 8.4 20.7 13 5.7 0.1 5.1 5 0 0 5 5 5 0 AN1-like Zinc finger zf-HYPF PF07503.7 EMC90557.1 - 6.3 6.2 15.5 4 6.9 1.2 4.0 4 1 0 4 4 4 0 HypF finger DUF2180 PF09947.4 EMC90557.1 - 8.5 6.2 9.3 1.3 8.8 1.8 2.6 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Kua-UEV1_localn PF10520.4 EMC90558.1 - 1.6e-31 109.3 2.4 2.3e-31 108.8 1.7 1.2 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain UQ_con PF00179.21 EMC90558.1 - 1.9e-18 66.2 0.0 3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMC90558.1 - 0.0025 17.6 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain RRM_1 PF00076.17 EMC90559.1 - 2.5e-12 46.2 0.0 5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC90559.1 - 5.3e-08 32.5 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC90559.1 - 9e-08 31.9 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4349 PF14257.1 EMC90559.1 - 0.027 13.6 1.1 0.053 12.7 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) BUD22 PF09073.5 EMC90559.1 - 0.035 13.1 5.9 0.052 12.6 4.1 1.1 1 0 0 1 1 1 0 BUD22 RP-C_C PF11800.3 EMC90559.1 - 0.11 12.1 1.6 0.17 11.6 1.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PilO PF04350.8 EMC90559.1 - 0.19 11.5 1.6 0.26 11.1 0.7 1.5 2 0 0 2 2 2 0 Pilus assembly protein, PilO DUF4611 PF15387.1 EMC90559.1 - 0.4 10.8 6.3 0.12 12.5 2.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Perilipin PF03036.11 EMC90561.1 - 1.8e-42 145.5 1.7 2e-42 145.4 1.2 1.0 1 0 0 1 1 1 1 Perilipin family Snf7 PF03357.16 EMC90562.1 - 7.6e-46 155.6 8.6 7.6e-46 155.6 6.0 1.8 2 0 0 2 2 2 1 Snf7 AAA_27 PF13514.1 EMC90562.1 - 0.054 11.1 6.0 0.065 10.9 4.2 1.1 1 0 0 1 1 1 0 AAA domain SYF2 PF08231.7 EMC90562.1 - 0.34 11.0 4.5 0.12 12.5 0.9 1.7 2 0 0 2 2 2 0 SYF2 splicing factor Enkurin PF13864.1 EMC90562.1 - 5.8 7.1 13.0 0.69 10.1 0.1 3.0 1 1 2 3 3 3 0 Calmodulin-binding zf-H2C2_2 PF13465.1 EMC90563.1 - 7.6e-37 123.8 94.7 1.3e-08 34.6 0.0 13.4 13 0 0 13 13 13 9 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90563.1 - 2.6e-34 115.5 111.7 9.3e-05 22.5 0.9 12.5 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90563.1 - 9.8e-31 103.8 98.9 0.0014 18.7 0.2 12.4 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90563.1 - 6.9e-12 45.1 79.7 0.0061 16.6 1.7 11.9 11 1 1 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC90563.1 - 2.5e-07 30.3 79.5 0.025 14.4 3.0 11.8 12 0 0 12 12 12 6 C2H2-type zinc finger BolA PF01722.13 EMC90563.1 - 9.4e-07 28.7 8.6 0.0015 18.4 0.1 4.2 3 2 1 4 4 4 2 BolA-like protein zf-met PF12874.2 EMC90563.1 - 3.2e-05 23.9 75.7 0.85 9.9 2.8 11.9 12 0 0 12 12 12 7 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMC90563.1 - 0.00022 21.2 65.1 0.19 11.8 0.6 8.5 2 2 7 9 9 9 6 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 EMC90563.1 - 0.00098 18.6 10.3 1.3 8.6 0.5 4.2 3 0 0 3 3 3 3 GAGA factor RRN7 PF11781.3 EMC90563.1 - 0.41 10.1 5.8 44 3.7 0.0 4.6 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Tim17 PF02466.14 EMC90564.1 - 8.2e-25 87.3 0.7 1.2e-24 86.8 0.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TPR_16 PF13432.1 EMC90564.1 - 1.4 9.7 5.6 0.6 10.8 2.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat EF-hand_5 PF13202.1 EMC90566.1 - 4.5e-08 32.0 4.8 7.1e-07 28.2 1.1 2.5 1 1 1 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMC90566.1 - 7.4e-08 31.8 2.6 1.5e-05 24.4 0.3 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMC90566.1 - 6.3e-07 28.2 3.7 1.8e-06 26.8 0.9 2.4 1 1 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMC90566.1 - 1.1e-06 28.6 0.1 2.5e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMC90566.1 - 7.2e-05 22.3 2.8 0.00068 19.3 0.6 2.5 2 0 0 2 2 2 1 EF-hand domain Syntaxin PF00804.20 EMC90566.1 - 0.003 17.7 0.8 0.04 14.0 0.1 2.2 2 0 0 2 2 2 1 Syntaxin ABM PF03992.11 EMC90566.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Baculo_PEP_C PF04513.7 EMC90566.1 - 0.31 10.8 1.3 0.4 10.4 0.2 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMG_box PF00505.14 EMC90567.1 - 9.8e-11 41.7 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMC90567.1 - 3.8e-09 36.7 0.1 7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 EMC90567.1 - 0.079 13.1 0.3 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 YABBY protein Mitofilin PF09731.4 EMC90567.1 - 0.77 8.3 7.6 1 7.8 5.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Glyco_hydro_47 PF01532.15 EMC90568.1 - 4.4e-146 487.1 0.0 5.3e-146 486.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3689 PF12463.3 EMC90569.1 - 3.1e-133 443.2 13.5 4.7e-133 442.6 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Myosin_tail_1 PF01576.14 EMC90570.1 - 0 1113.8 275.6 0 1095.9 144.3 3.0 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 EMC90570.1 - 5.1e-267 887.4 0.2 5.1e-267 887.4 0.1 3.5 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 EMC90570.1 - 7.3e-14 51.1 7.5 1.8e-13 49.9 5.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 EMC90570.1 - 1.3e-08 34.6 231.9 1.4e-06 27.9 28.0 9.4 1 1 6 7 7 7 4 Intermediate filament protein Reo_sigmaC PF04582.7 EMC90570.1 - 1.1e-06 28.0 80.8 0.00045 19.4 3.4 10.2 1 1 10 12 12 12 9 Reovirus sigma C capsid protein DUF869 PF05911.6 EMC90570.1 - 8.4e-06 24.3 7.5 8.4e-06 24.3 5.2 7.2 1 1 5 6 6 6 2 Plant protein of unknown function (DUF869) IncA PF04156.9 EMC90570.1 - 0.00052 19.6 260.7 0.07 12.7 15.7 12.1 1 1 10 11 11 11 5 IncA protein TMF_DNA_bd PF12329.3 EMC90570.1 - 0.0048 16.6 21.6 0.0048 16.6 15.0 18.5 7 5 12 20 20 20 5 TATA element modulatory factor 1 DNA binding IQ PF00612.22 EMC90570.1 - 0.006 16.1 1.3 0.07 12.8 0.2 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.1 EMC90570.1 - 0.12 12.5 0.0 0.12 12.5 0.0 6.6 5 3 1 7 7 7 0 AAA domain GSH_synth_ATP PF03917.12 EMC90571.1 - 3.1e-134 447.2 0.0 3.5e-134 447.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EMC90571.1 - 1.5e-35 121.4 0.3 3.2e-35 120.3 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MAM PF00629.18 EMC90573.1 - 2e-34 118.6 0.0 3.6e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 MAM domain fn3 PF00041.16 EMC90573.1 - 1.8e-16 60.0 1.0 2.8e-07 30.5 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain Y_phosphatase PF00102.22 EMC90574.1 - 2e-152 505.1 1.6 1.8e-84 282.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EMC90574.1 - 1.3e-09 37.7 0.1 0.00073 19.1 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain fn3 PF00041.16 EMC90574.1 - 1.8e-07 31.1 0.1 0.00077 19.5 0.0 3.8 2 1 1 3 3 3 2 Fibronectin type III domain Y_phosphatase3 PF13350.1 EMC90574.1 - 5.9e-06 26.6 0.1 0.011 16.0 0.0 2.7 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMC90574.1 - 2.7e-05 24.2 0.0 0.28 11.2 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Antimicrobial_6 PF08036.6 EMC90574.1 - 0.011 15.4 0.9 2.4 7.9 0.1 2.9 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide DctM PF06808.7 EMC90574.1 - 0.13 10.7 0.1 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 DctM-like transporters ABC_transp_aux PF09822.4 EMC90576.1 - 1.7e-09 37.5 0.0 8.8e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 ABC-type uncharacterized transport system DUF4159 PF13709.1 EMC90576.1 - 0.13 11.3 0.0 0.46 9.5 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4159) Pkinase PF00069.20 EMC90577.1 - 5.6e-71 238.7 0.0 6.4e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90577.1 - 3.2e-35 121.4 0.0 3.9e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMC90577.1 - 9e-06 26.1 0.2 1.6e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMC90577.1 - 2.1e-05 23.6 0.0 7.2e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMC90577.1 - 0.00051 19.1 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMC90577.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aa_trans PF01490.13 EMC90578.1 - 1.1e-92 310.6 19.2 1.5e-92 310.2 13.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.22 EMC90579.1 - 1.1e-42 145.1 0.4 1.1e-42 145.1 0.3 2.1 2 1 0 2 2 2 1 RhoGAP domain H_kinase_N PF12282.3 EMC90579.1 - 0.08 12.5 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal transduction histidine kinase Actin PF00022.14 EMC90580.1 - 7.8e-43 146.3 0.0 3.4e-41 140.9 0.0 2.1 1 1 0 1 1 1 1 Actin DUF1542 PF07564.6 EMC90580.1 - 0.051 13.5 1.5 0.76 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) PDDEXK_1 PF12705.2 EMC90580.1 - 0.94 8.7 6.1 1.6 8.0 4.3 1.4 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Ank PF00023.25 EMC90581.1 - 3.1e-41 137.1 15.3 7.1e-10 38.2 0.4 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EMC90581.1 - 6.9e-41 138.4 14.4 9.4e-19 67.5 1.9 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC90581.1 - 3.3e-33 113.4 9.7 1.4e-14 54.1 0.4 5.8 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC90581.1 - 1e-30 105.0 15.5 1.4e-11 44.1 2.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC90581.1 - 2.5e-22 76.7 11.5 1.2e-05 25.0 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat RepB-RCR_reg PF10723.4 EMC90581.1 - 0.0085 15.7 3.0 0.0085 15.7 2.1 2.6 3 0 0 3 3 3 1 Replication regulatory protein RepB APG6 PF04111.7 EMC90581.1 - 0.16 11.0 5.7 0.3 10.1 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4337 PF14235.1 EMC90581.1 - 0.22 11.3 3.9 0.47 10.2 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1669 PF07894.7 EMC90582.1 - 1.6e-56 191.6 0.2 2.6e-56 190.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 EMC90582.1 - 9.4e-05 22.1 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain DUF1669 PF07894.7 EMC90583.1 - 1.8e-39 135.6 0.5 2.8e-27 95.6 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 EMC90583.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain DUF3023 PF11224.3 EMC90583.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) OB_NTP_bind PF07717.11 EMC90584.1 - 1.2e-27 96.0 0.0 2.4e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMC90584.1 - 4e-25 87.7 0.2 1.2e-24 86.2 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMC90584.1 - 6.1e-10 38.8 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 EMC90584.1 - 0.00012 22.3 0.2 0.031 14.5 0.0 2.5 1 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EMC90584.1 - 0.0024 18.0 0.1 0.013 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain UPF0203 PF05254.7 EMC90584.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) bZIP_Maf PF03131.12 EMC90585.1 - 2.8e-35 120.4 11.8 2.8e-35 120.4 8.2 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor Maf_N PF08383.6 EMC90585.1 - 1.9e-21 75.2 1.3 5.7e-21 73.7 0.9 1.9 1 0 0 1 1 1 1 Maf N-terminal region CCDC155 PF14662.1 EMC90585.1 - 0.001 18.7 3.3 0.0019 17.8 2.3 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 EMC90585.1 - 0.0026 17.6 11.8 0.0049 16.7 8.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor HOOK PF05622.7 EMC90585.1 - 0.0098 13.7 6.5 0.014 13.2 4.5 1.1 1 0 0 1 1 1 1 HOOK protein Spc24 PF08286.6 EMC90585.1 - 0.038 13.6 0.6 0.076 12.7 0.4 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1192 PF06698.6 EMC90585.1 - 0.045 13.5 1.7 9.5 6.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.10 EMC90585.1 - 0.13 12.1 11.1 0.28 11.0 7.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper MbeD_MobD PF04899.7 EMC90585.1 - 0.43 10.5 7.0 0.1 12.5 1.8 2.3 2 0 0 2 2 2 0 MbeD/MobD like Seryl_tRNA_N PF02403.17 EMC90585.1 - 1 9.4 7.1 2.2 8.3 4.9 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UPF0449 PF15136.1 EMC90585.1 - 4.2 7.6 7.5 4.3 7.5 3.7 2.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Topoisom_I_N PF02919.10 EMC90586.1 - 1.1e-102 341.9 8.1 1.1e-102 341.9 5.6 5.1 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EMC90586.1 - 2.7e-97 324.4 4.8 2.7e-97 324.4 3.3 3.3 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EMC90586.1 - 3.1e-34 116.4 0.5 4.6e-33 112.7 0.3 3.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain Hanta_nucleocap PF00846.13 EMC90586.1 - 0.00043 19.1 7.1 0.00084 18.1 4.9 1.4 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein PI-PLC-X PF00388.14 EMC90587.1 - 9.6e-66 219.6 0.3 2e-65 218.6 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.19 EMC90587.1 - 2.8e-47 158.3 1.0 1.9e-24 85.2 0.0 3.3 3 0 0 3 3 3 2 SH2 domain PI-PLC-Y PF00387.14 EMC90587.1 - 8.3e-43 145.1 0.1 1.7e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 PF00018.23 EMC90587.1 - 5.9e-16 57.5 0.6 1.5e-15 56.2 0.4 1.8 1 0 0 1 1 1 1 SH3 domain C2 PF00168.25 EMC90587.1 - 2.8e-15 55.9 0.0 7.8e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.1 EMC90587.1 - 9.5e-13 47.5 0.9 1.4e-11 43.7 0.2 2.6 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.24 EMC90587.1 - 2.6e-10 40.4 0.1 0.19 11.9 0.0 4.2 4 0 0 4 4 4 3 PH domain SH3_2 PF07653.12 EMC90587.1 - 5.3e-09 35.4 0.1 1.1e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_like PF09279.6 EMC90587.1 - 3.2e-07 30.2 0.4 9.7e-07 28.7 0.3 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 EMC90587.1 - 0.0001 21.9 0.0 0.0004 19.9 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_7 PF13499.1 EMC90587.1 - 0.021 14.9 2.4 0.094 12.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EMC90587.1 - 0.06 13.2 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain LNS2 PF08235.8 EMC90588.1 - 3.2e-68 228.2 0.0 4.9e-68 227.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EMC90588.1 - 7.4e-48 160.8 0.0 1.3e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region EMI PF07546.8 EMC90589.1 - 9.7e-20 70.8 5.6 9.7e-20 70.8 3.9 2.5 3 0 0 3 3 3 1 EMI domain Myosin_tail_1 PF01576.14 EMC90589.1 - 4.7e-05 21.3 18.7 0.00012 20.0 3.6 2.4 2 1 0 2 2 2 2 Myosin tail NPV_P10 PF05531.7 EMC90589.1 - 8.4e-05 22.7 12.4 6.6 7.0 0.2 7.8 6 1 2 9 9 9 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EMC90589.1 - 0.0018 18.0 14.7 0.0097 15.6 0.8 5.7 4 3 1 5 5 5 1 Protein of unknown function (DUF1664) CorA PF01544.13 EMC90589.1 - 0.0049 15.9 4.4 0.0049 15.9 3.1 3.5 3 1 1 4 4 4 2 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.7 EMC90589.1 - 0.0062 16.2 24.1 0.014 15.1 0.2 5.9 5 2 1 6 6 6 2 TPR/MLP1/MLP2-like protein AF0941-like PF14591.1 EMC90589.1 - 0.0098 15.9 2.9 0.88 9.6 0.1 3.8 3 1 0 3 3 3 1 AF0941-like Reo_sigmaC PF04582.7 EMC90589.1 - 0.022 13.9 20.1 1.7 7.7 0.0 4.7 2 1 2 5 5 5 0 Reovirus sigma C capsid protein WXG100 PF06013.7 EMC90589.1 - 0.043 13.8 3.6 3.4 7.7 0.0 5.5 6 2 0 6 6 6 0 Proteins of 100 residues with WXG Spc7 PF08317.6 EMC90589.1 - 0.088 11.4 23.5 0.062 11.9 0.7 4.6 2 2 3 5 5 5 0 Spc7 kinetochore protein IncA PF04156.9 EMC90589.1 - 0.12 11.9 26.2 6.2 6.3 0.0 5.4 2 1 3 5 5 5 0 IncA protein Bacillus_HBL PF05791.6 EMC90589.1 - 0.15 11.4 14.2 0.99 8.7 0.6 4.8 3 1 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) HCMV_UL139 PF12507.3 EMC90589.1 - 0.61 10.2 7.4 11 6.1 0.0 4.0 4 1 1 5 5 5 0 Human Cytomegalovirus UL139 protein DUF3573 PF12097.3 EMC90589.1 - 1.8 7.1 7.3 0.28 9.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Fzo_mitofusin PF04799.8 EMC90589.1 - 4 6.7 15.5 0.32 10.3 2.1 4.1 3 1 1 4 4 4 0 fzo-like conserved region Ribophorin_II PF05817.9 EMC90590.1 - 2e-266 885.3 7.4 2.2e-266 885.1 5.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Hormone_2 PF00123.15 EMC90591.1 - 4.6e-13 48.7 0.1 1.6e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Peptide hormone UPF0239 PF06783.6 EMC90592.1 - 1.1e-34 118.2 0.2 1.2e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) BC10 PF06726.7 EMC90593.1 - 4.4e-27 93.8 10.2 5.7e-27 93.5 7.1 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Dysbindin PF04440.11 EMC90594.1 - 5.4e-35 120.2 8.0 5.4e-35 120.2 5.5 1.8 1 1 1 2 2 2 1 Dysbindin (Dystrobrevin binding protein 1) SYS1 PF09801.4 EMC90595.1 - 4.8e-38 130.3 3.2 5.3e-38 130.2 2.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Tweety PF04906.8 EMC90595.1 - 0.31 9.4 2.7 0.13 10.6 0.5 1.4 1 1 0 1 1 1 0 Tweety Oxidored_q2 PF00420.19 EMC90595.1 - 0.9 9.1 4.1 6.8 6.3 3.0 1.9 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Syndecan PF01034.15 EMC90596.1 - 4.3e-24 83.9 0.1 6.7e-24 83.3 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.6 EMC90596.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protocadherin Herpes_gE PF02480.11 EMC90596.1 - 0.044 12.0 0.0 0.056 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E BTD PF09270.5 EMC90597.1 - 2.4e-62 209.3 0.0 7.4e-62 207.7 0.0 1.8 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EMC90597.1 - 1.1e-50 171.7 0.0 1.6e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 LAG1, DNA binding VWA PF00092.23 EMC90598.1 - 1.9e-96 320.8 0.3 4e-49 166.7 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain FXa_inhibition PF14670.1 EMC90598.1 - 7.1e-32 109.2 62.3 1.2e-09 38.1 6.3 4.5 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site VWA_2 PF13519.1 EMC90598.1 - 1.2e-30 106.8 0.0 9.9e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain cEGF PF12662.2 EMC90598.1 - 1.1e-21 76.1 32.0 2.3e-07 30.2 1.7 4.8 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.10 EMC90598.1 - 1.6e-19 69.5 49.9 5.5e-07 29.4 4.0 4.4 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.22 EMC90598.1 - 1.5e-11 44.0 45.0 0.0033 17.3 3.6 4.7 4 0 0 4 4 4 4 EGF-like domain vWA-TerF-like PF10138.4 EMC90598.1 - 4e-09 36.5 0.6 0.00035 20.4 0.0 2.2 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_3 PF13768.1 EMC90598.1 - 5.9e-09 35.7 0.1 0.0028 17.3 0.0 2.5 2 1 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.4 EMC90598.1 - 1.6e-07 30.5 0.5 5.6e-07 28.8 0.3 2.0 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin EGF_3 PF12947.2 EMC90598.1 - 0.00084 19.2 52.4 0.031 14.2 5.5 4.7 4 0 0 4 4 4 2 EGF domain ClpB_D2-small PF10431.4 EMC90598.1 - 0.11 12.4 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Ion_trans PF00520.26 EMC90599.1 - 7e-32 110.2 2.3 1.6e-31 109.1 0.4 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 EMC90599.1 - 1.2e-29 102.3 0.1 2.7e-29 101.2 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 EMC90599.1 - 4e-10 39.2 4.8 4e-10 39.2 3.3 2.0 2 0 0 2 2 2 1 Ion channel RhoGAP PF00620.22 EMC90600.1 - 1.6e-11 44.0 0.1 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Ten_N PF06484.7 EMC90601.1 - 3.5e-34 118.5 7.7 3.9e-34 118.3 5.3 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region tRNA-synt_2 PF00152.15 EMC90602.1 - 2.3e-75 253.4 0.0 2.8e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMC90602.1 - 5e-09 35.8 0.0 8.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMC90602.1 - 0.001 18.2 0.8 1.1 8.3 0.2 2.6 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) PH PF00169.24 EMC90603.1 - 4.2e-16 59.0 0.7 1.1e-14 54.5 0.1 2.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EMC90603.1 - 6.9e-07 29.5 1.3 5e-06 26.7 0.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMC90603.1 - 0.098 12.5 0.3 0.29 11.0 0.2 1.8 1 1 0 1 1 1 0 PH domain UCH PF00443.24 EMC90604.1 - 3.5e-49 167.3 0.0 6.4e-49 166.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMC90604.1 - 7.7e-29 101.0 0.0 1.8e-28 99.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DDR PF08841.5 EMC90604.1 - 0.43 9.3 0.1 0.65 8.7 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BTB_2 PF02214.17 EMC90605.1 - 8.4e-22 77.1 0.0 1.7e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EMC90605.1 - 0.029 14.3 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain NDUF_C2 PF06374.6 EMC90606.1 - 1.3e-23 83.1 0.1 1.5e-23 83.0 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Spot_14 PF07084.7 EMC90607.1 - 3.7e-24 85.3 0.1 4.8e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Spot_14 PF07084.7 EMC90608.1 - 4.6e-24 85.0 0.1 6.4e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Spot_14 PF07084.7 EMC90609.1 - 6.8e-23 81.3 0.1 8.7e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Med2 PF11214.3 EMC90609.1 - 0.016 15.2 0.6 0.024 14.6 0.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 BTB_2 PF02214.17 EMC90610.1 - 1.4e-16 60.5 0.0 2.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TNF PF00229.13 EMC90610.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family HEAT PF02985.17 EMC90611.1 - 6.4e-26 88.0 5.3 0.00076 19.3 0.0 8.6 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 EMC90611.1 - 8e-21 74.1 3.7 8.4e-07 29.1 0.1 5.7 2 2 2 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 EMC90611.1 - 6.4e-11 41.2 3.9 0.00014 20.3 0.1 3.3 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.2 EMC90611.1 - 2.6e-09 37.1 2.9 9.6e-06 25.5 0.3 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EMC90611.1 - 5.6e-08 33.0 2.4 0.00017 21.9 0.1 4.5 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMC90611.1 - 3.8e-07 30.3 8.0 0.12 12.8 0.3 6.7 7 1 1 8 8 8 2 HEAT-like repeat CLASP_N PF12348.3 EMC90611.1 - 1.3e-05 24.6 0.7 2.1 7.6 0.1 4.3 2 2 3 5 5 5 2 CLASP N terminal Cohesin_HEAT PF12765.2 EMC90611.1 - 7e-05 22.6 0.0 0.42 10.6 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 EMC90611.1 - 0.0022 17.0 1.7 0.68 8.8 0.0 3.1 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain DUF445 PF04286.7 EMC90611.1 - 0.0034 16.9 3.9 0.16 11.4 1.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF445) API5 PF05918.6 EMC90611.1 - 0.052 12.0 0.1 0.22 9.9 0.0 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) HEAT_PBS PF03130.11 EMC90611.1 - 0.11 12.9 0.6 35 5.2 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF498 PF04430.9 EMC90612.1 - 6.4e-23 80.4 0.0 7.1e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Voldacs PF03517.8 EMC90613.1 - 6.1e-34 116.7 1.6 8.7e-34 116.2 1.1 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling MIP PF00230.15 EMC90614.1 - 1.9e-11 43.9 8.4 1.7e-10 40.7 5.8 2.1 1 1 0 1 1 1 1 Major intrinsic protein LGT PF01790.13 EMC90614.1 - 0.061 12.2 4.0 0.9 8.4 2.7 2.5 1 1 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase Pkinase PF00069.20 EMC90615.1 - 8.9e-73 244.6 0.0 1.9e-72 243.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90615.1 - 3.6e-47 160.5 0.0 5.7e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMC90615.1 - 2.5e-24 85.4 0.4 1e-23 83.4 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EMC90615.1 - 2.6e-08 33.1 0.0 8e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMC90615.1 - 0.0015 18.2 0.0 0.022 14.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.7 EMC90615.1 - 0.004 16.4 0.0 0.0084 15.3 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Kdo PF06293.9 EMC90615.1 - 0.1 11.6 0.0 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family GDPD PF03009.12 EMC90616.1 - 1.8e-19 70.2 0.0 2.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Peptidase_C2 PF00648.16 EMC90617.1 - 2.5e-99 332.0 1.2 3.6e-99 331.5 0.8 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMC90617.1 - 1.9e-45 154.0 0.0 3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.25 EMC90617.1 - 1.4e-14 53.6 0.0 3.5e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ceramidase PF05875.7 EMC90619.1 - 2.2e-65 220.4 16.8 2.7e-65 220.1 11.6 1.0 1 0 0 1 1 1 1 Ceramidase O-ag_pol_Wzy PF14296.1 EMC90619.1 - 0.64 8.5 17.5 0.42 9.1 1.8 2.2 1 1 1 2 2 2 0 O-antigen polysaccharide polymerase Wzy LRR_8 PF13855.1 EMC90620.1 - 2e-46 155.5 61.9 2.4e-12 46.4 1.4 6.2 1 1 6 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EMC90620.1 - 3.9e-25 83.9 27.2 0.0032 17.2 0.2 10.5 9 1 1 10 10 10 8 Leucine Rich Repeat LRR_4 PF12799.2 EMC90620.1 - 1.7e-24 84.9 35.1 1.9e-07 30.5 0.6 7.1 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 EMC90620.1 - 2.3e-12 46.7 0.0 7.6e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC90620.1 - 3.5e-10 38.3 30.1 0.13 12.5 0.2 9.3 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 EMC90620.1 - 2.1e-09 36.4 35.1 0.86 9.8 0.0 10.1 7 3 3 10 10 10 4 Leucine Rich repeat LRRNT PF01462.13 EMC90620.1 - 0.072 12.6 2.8 0.19 11.2 0.5 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain HNOBA PF07701.9 EMC90621.1 - 1.1e-06 27.9 1.1 1.2e-06 27.9 0.7 1.0 1 0 0 1 1 1 1 Heme NO binding associated AF0941-like PF14591.1 EMC90621.1 - 0.088 12.8 0.3 0.096 12.7 0.2 1.1 1 0 0 1 1 1 0 AF0941-like Motilin_assoc PF04643.7 EMC90621.1 - 0.097 12.1 0.3 2.1 7.9 0.1 2.1 1 1 1 2 2 2 0 Motilin/ghrelin-associated peptide ENT PF03735.9 EMC90622.1 - 1.9e-28 97.9 0.2 4e-28 96.9 0.2 1.6 1 0 0 1 1 1 1 ENT domain DUF4371 PF14291.1 EMC90624.1 - 1.1e-16 61.1 0.3 3.2e-16 59.5 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.9 EMC90624.1 - 3.9e-10 39.2 0.1 8.3e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region THAP PF05485.7 EMC90624.1 - 1.1e-08 35.1 0.3 2.6e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 THAP domain wnt PF00110.14 EMC90625.1 - 5.2e-106 354.3 17.7 5.9e-106 354.1 12.3 1.0 1 0 0 1 1 1 1 wnt family Atg14 PF10186.4 EMC90626.1 - 3.2e-22 78.8 8.9 4.7e-22 78.3 6.2 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EMC90626.1 - 2.8e-07 29.8 5.9 4.9e-07 29.0 4.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 C2 PF00168.25 EMC90626.1 - 7.2e-06 25.7 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain TPR_MLP1_2 PF07926.7 EMC90626.1 - 0.18 11.5 13.0 0.41 10.3 9.0 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 EMC90626.1 - 1.8 6.9 11.1 2.7 6.2 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EMC90626.1 - 2.6 5.7 6.9 3.7 5.2 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMC90626.1 - 3.4 7.2 18.7 7.7 6.0 12.9 1.5 1 0 0 1 1 1 0 IncA protein DAGAT PF03982.8 EMC90627.1 - 5.1e-143 475.1 0.0 6.2e-143 474.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 EMC90627.1 - 0.0035 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase STOP PF05217.7 EMC90629.1 - 7.4e-14 51.9 8.1 3.5e-07 30.1 1.1 2.4 2 0 0 2 2 2 2 STOP protein Clr5 PF14420.1 EMC90629.1 - 0.6 10.0 6.6 0.93 9.4 0.3 3.1 3 0 0 3 3 3 0 Clr5 domain Kelch_1 PF01344.20 EMC90630.1 - 6e-57 188.9 5.0 3.4e-12 45.7 0.0 6.8 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EMC90630.1 - 1.6e-38 129.3 8.6 5e-09 35.9 0.0 6.5 4 1 2 6 6 6 5 Kelch motif BACK PF07707.10 EMC90630.1 - 6.9e-33 112.5 0.3 2.9e-32 110.5 0.2 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 EMC90630.1 - 1.1e-30 105.8 0.0 3.4e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 EMC90630.1 - 8.6e-28 95.0 6.1 1.9e-05 24.2 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EMC90630.1 - 1.2e-26 92.2 6.5 0.00017 21.3 0.0 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EMC90630.1 - 4.6e-25 87.1 2.4 0.0016 18.5 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMC90630.1 - 8.5e-15 54.3 10.8 0.015 15.2 0.1 6.1 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 EMC90630.1 - 0.0002 20.5 0.1 0.00049 19.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Pput2613-deam PF14427.1 EMC90630.1 - 0.15 11.7 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Pput_2613-like deaminase GDPD PF03009.12 EMC90631.1 - 4.3e-22 78.8 0.0 1.9e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family ESSS PF10183.4 EMC90631.1 - 2.8 8.3 4.8 1.1 9.6 0.9 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Serpin PF00079.15 EMC90632.1 - 5.3e-98 328.5 0.6 6e-98 328.3 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Ribosomal_S3_C PF00189.15 EMC90633.1 - 2.3e-16 59.7 0.1 4.3e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EMC90633.1 - 6.2e-12 44.9 0.1 1e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 KH domain SH3_1 PF00018.23 EMC90634.1 - 2.8e-26 90.6 1.5 1.4e-12 46.8 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMC90634.1 - 1.1e-24 85.7 1.5 8e-14 50.9 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMC90634.1 - 3.3e-21 74.5 0.2 1e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EMC90634.1 - 7.1e-06 26.1 0.2 7.1e-06 26.1 0.1 3.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.6 EMC90634.1 - 0.0049 17.0 0.1 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain H-kinase_dim PF02895.9 EMC90634.1 - 0.26 11.6 3.3 5.7 7.3 0.0 3.3 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF342 PF03961.8 EMC90634.1 - 9.4 4.5 11.3 0.65 8.3 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF3470 PF11953.3 EMC90635.1 - 0.0005 19.6 6.2 67 3.1 0.0 6.7 9 0 0 9 9 9 5 Domain of unknown function (DUF3470) 7tm_1 PF00001.16 EMC90637.1 - 8.8e-49 165.9 17.1 1.1e-48 165.5 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EMC90637.1 - 0.0029 16.7 12.5 0.0042 16.2 8.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv RELT PF12606.3 EMC90638.1 - 5.9e-14 50.9 0.0 1.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 TCRP1 PF14944.1 EMC90639.1 - 1.1e-84 283.2 37.6 1.3e-84 282.9 26.0 1.1 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 PT PF04886.7 EMC90639.1 - 0.022 14.0 2.7 0.022 14.0 1.9 2.7 2 0 0 2 2 2 0 PT repeat Ras PF00071.17 EMC90642.1 - 1.7e-53 180.2 0.4 2.1e-53 180.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC90642.1 - 1.5e-18 67.4 0.1 3e-18 66.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMC90642.1 - 5.4e-12 45.2 0.8 6.6e-12 45.0 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMC90642.1 - 1.4e-05 24.6 0.1 2.4e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMC90642.1 - 0.0008 18.6 0.1 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMC90642.1 - 0.007 16.3 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMC90642.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EMC90642.1 - 0.036 13.2 0.2 0.042 12.9 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S10 PF00338.17 EMC90643.1 - 2.3e-14 53.0 0.3 3.8e-14 52.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e CarD_CdnL_TRCF PF02559.11 EMC90643.1 - 0.096 12.7 0.1 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 CarD-like/TRCF domain WD40 PF00400.27 EMC90644.1 - 1.9e-28 97.2 9.8 3.4e-08 33.0 0.2 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMC90644.1 - 0.013 14.2 0.0 0.5 9.0 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like Abhydrolase_6 PF12697.2 EMC90645.1 - 3.7e-29 102.2 0.0 1.1e-28 100.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMC90645.1 - 4.4e-12 45.9 0.0 6.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMC90645.1 - 7.3e-11 42.0 0.0 9.7e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMC90645.1 - 0.0003 20.4 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMC90645.1 - 0.00045 20.5 0.0 0.00085 19.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EMC90645.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EMC90645.1 - 0.0033 17.2 0.0 0.0084 15.9 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Lipase_3 PF01764.20 EMC90645.1 - 0.0037 16.8 0.0 0.0093 15.5 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EMC90645.1 - 0.0078 15.6 0.1 0.036 13.4 0.1 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EMC90645.1 - 0.0093 15.4 1.9 1.4 8.3 0.1 2.7 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase Prothymosin PF03247.9 EMC90645.1 - 0.054 13.6 8.9 0.12 12.5 6.2 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF2974 PF11187.3 EMC90645.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) 2OG-FeII_Oxy PF03171.15 EMC90646.1 - 1e-10 41.7 0.0 2.2e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMC90646.1 - 6.9e-08 32.9 0.0 1.5e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPC25 PF06703.6 EMC90648.1 - 1.3e-34 119.1 0.3 1.9e-22 79.5 0.1 2.0 1 1 1 2 2 2 2 Microsomal signal peptidase 25 kDa subunit (SPC25) Sof1 PF04158.9 EMC90649.1 - 4.4e-35 119.5 10.6 7.1e-35 118.9 7.3 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 EMC90649.1 - 6.1e-29 98.8 8.8 6.1e-06 25.9 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EMC90649.1 - 2.8e-07 30.4 0.8 0.0002 21.0 0.0 3.6 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Mito_carr PF00153.22 EMC90650.1 - 4.4e-64 212.2 3.4 4.7e-24 83.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Collagen PF01391.13 EMC90651.1 - 2.8e-07 29.9 6.9 4.7e-07 29.2 4.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Orn_Arg_deC_N PF02784.11 EMC90653.1 - 2.9e-58 197.0 0.0 3.6e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EMC90653.1 - 9.5e-21 73.6 0.0 1.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-C2H2 PF00096.21 EMC90655.1 - 7.4e-12 44.8 22.3 0.00046 20.3 2.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC90655.1 - 9.3e-12 44.6 9.7 1.5e-07 31.3 1.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC90655.1 - 6e-10 38.7 19.4 0.00057 20.0 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger RRN7 PF11781.3 EMC90655.1 - 0.0068 15.8 2.9 0.58 9.7 0.1 2.6 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-TRAF PF02176.13 EMC90655.1 - 0.26 11.7 6.4 0.089 13.1 0.8 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 EMC90655.1 - 0.56 10.3 9.9 0.15 12.1 1.0 2.7 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 EMC90655.1 - 5 6.9 10.3 0.15 11.8 1.0 2.4 2 0 0 2 2 2 0 BED zinc finger HSP20 PF00011.16 EMC90656.1 - 1.7e-09 37.4 0.1 1.8e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HECT PF00632.20 EMC90657.1 - 9.2e-64 215.5 0.0 1.5e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.3 EMC90657.1 - 1.1e-33 114.5 3.4 1.1e-33 114.5 2.4 2.2 2 0 0 2 2 2 1 E3 ubiquitin ligase EDD PABP PF00658.13 EMC90657.1 - 2e-22 78.6 0.0 4.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-UBR PF02207.15 EMC90657.1 - 2.6e-07 30.2 21.9 5.8e-07 29.1 15.2 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Ribonuc_red_sm PF00268.16 EMC90658.1 - 1.8e-123 411.0 0.7 2.1e-123 410.8 0.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Trypan_PARP PF05887.6 EMC90659.1 - 2.2e-09 37.2 19.4 3.4e-09 36.6 13.5 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 EMC90659.1 - 0.0001 21.7 28.5 0.00017 21.0 19.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EMC90659.1 - 0.00011 20.1 13.6 0.00013 19.8 9.4 1.1 1 0 0 1 1 1 1 Ycf1 Serinc PF03348.10 EMC90659.1 - 0.0014 17.4 2.1 0.003 16.3 1.5 1.5 1 0 0 1 1 1 1 Serine incorporator (Serinc) DDHD PF02862.12 EMC90659.1 - 0.0023 17.7 10.3 0.012 15.4 7.5 2.1 2 0 0 2 2 2 1 DDHD domain SID-1_RNA_chan PF13965.1 EMC90659.1 - 0.0092 14.1 0.5 0.012 13.8 0.4 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 PA26 PF04636.8 EMC90659.1 - 0.027 13.1 4.9 0.041 12.5 3.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IncA PF04156.9 EMC90659.1 - 0.034 13.7 7.7 0.079 12.5 5.3 1.7 1 0 0 1 1 1 0 IncA protein Zip PF02535.17 EMC90659.1 - 0.062 12.3 7.1 0.12 11.3 4.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.7 EMC90659.1 - 0.093 11.8 16.8 0.14 11.2 11.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MIP-T3 PF10243.4 EMC90659.1 - 0.17 10.3 59.0 0.32 9.4 40.9 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TRAP_alpha PF03896.11 EMC90659.1 - 0.25 10.3 8.3 0.43 9.5 5.8 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF262 PF03235.9 EMC90659.1 - 0.45 10.4 8.8 0.64 9.9 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Dynamin_N PF00350.18 EMC90659.1 - 0.47 10.2 5.1 1.2 8.8 3.5 1.7 1 0 0 1 1 1 0 Dynamin family DUF2201_N PF13203.1 EMC90659.1 - 0.89 8.6 16.6 1.8 7.6 11.5 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Raftlin PF15250.1 EMC90659.1 - 1.1 7.6 17.0 1.8 7.0 11.8 1.2 1 0 0 1 1 1 0 Raftlin SpoIIP PF07454.6 EMC90659.1 - 4.7 6.3 19.6 7.1 5.7 13.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.5 EMC90659.1 - 5 7.1 43.7 11 5.9 30.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.11 EMC90659.1 - 5 6.4 31.9 9.2 5.5 22.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Nop14 PF04147.7 EMC90659.1 - 7.9 4.2 35.6 12 3.6 24.7 1.2 1 0 0 1 1 1 0 Nop14-like family DHHW PF14286.1 EMC90659.1 - 9.8 5.3 15.5 15 4.7 10.8 1.2 1 0 0 1 1 1 0 DHHW protein EF-hand_1 PF00036.27 EMC90660.1 - 2.4e-20 70.1 5.1 2.2e-07 29.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMC90660.1 - 4.2e-20 71.6 1.1 1.1e-10 41.4 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMC90660.1 - 1.6e-18 65.0 2.6 1e-06 27.8 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EMC90660.1 - 2.5e-17 61.1 0.7 3.5e-06 26.4 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EMC90660.1 - 1.1e-11 44.1 5.9 3.7e-06 26.4 0.2 4.3 1 1 3 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC90660.1 - 3.1e-05 23.9 0.0 0.035 14.1 0.0 2.6 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMC90660.1 - 0.00065 19.4 0.3 0.12 12.1 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand CP2 PF04516.10 EMC90661.1 - 3.2e-84 281.6 3.4 4.2e-84 281.3 2.3 1.1 1 0 0 1 1 1 1 CP2 transcription factor DUF2089 PF09862.4 EMC90661.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) 4F5 PF04419.9 EMC90662.1 - 1.5e-10 41.5 17.6 2.1e-10 41.1 12.2 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 EMC90662.1 - 2.6e-06 27.2 0.3 5e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding zf-met PF12874.2 EMC90662.1 - 4e-05 23.6 0.2 6.4e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMC90662.1 - 0.0067 16.5 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC90662.1 - 0.022 14.9 1.4 0.045 13.9 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 EMC90662.1 - 0.041 14.0 0.7 0.067 13.3 0.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.9 EMC90662.1 - 0.051 13.2 0.2 0.097 12.3 0.2 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PRP21_like_P PF12230.3 EMC90662.1 - 0.14 11.6 4.3 0.17 11.3 3.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2 PF00096.21 EMC90662.1 - 0.15 12.4 1.6 0.22 11.9 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ribosomal_L44 PF00935.14 EMC90662.1 - 0.18 11.8 6.6 0.33 11.0 4.6 1.5 1 1 0 1 1 1 0 Ribosomal protein L44 AKAP95 PF04988.7 EMC90662.1 - 0.4 10.4 0.1 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Potyvirid-P3 PF13608.1 EMC90662.1 - 0.42 9.6 2.4 0.46 9.5 1.7 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF3449 PF11931.3 EMC90662.1 - 6.3 6.2 8.2 1.3 8.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) 14-3-3 PF00244.15 EMC90663.1 - 1.1e-113 378.0 8.9 1.3e-113 377.9 6.1 1.0 1 0 0 1 1 1 1 14-3-3 protein CIA30 PF08547.7 EMC90663.1 - 0.05 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) FliM PF02154.10 EMC90663.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM CCDC-167 PF15188.1 EMC90663.1 - 1.1 9.2 4.7 0.76 9.7 0.3 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF3461 PF11944.3 EMC90663.1 - 1.3 8.9 4.4 10 5.9 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3461) RRM_1 PF00076.17 EMC90664.1 - 1.2e-69 229.9 5.4 4.8e-25 86.9 0.2 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC90664.1 - 1.2e-47 159.7 1.4 2.1e-16 59.6 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC90664.1 - 7.5e-37 124.9 0.7 2.5e-10 40.0 0.0 4.6 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EMC90664.1 - 5e-35 118.9 0.4 2.1e-34 117.0 0.2 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EMC90664.1 - 4.1e-07 29.6 1.9 0.12 12.1 0.1 3.6 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 EMC90664.1 - 6.8e-05 22.6 10.3 0.056 13.2 0.9 3.6 4 0 0 4 4 4 2 RNA binding motif CbiG_mid PF11761.3 EMC90664.1 - 0.0014 18.8 1.3 2 8.6 0.0 4.9 6 0 0 6 6 6 1 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 EMC90664.1 - 0.0016 18.1 0.0 2.3 8.0 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif ATP-grasp_2 PF08442.5 EMC90664.1 - 0.0017 17.8 0.3 1.8 7.8 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain DUF3421 PF11901.3 EMC90664.1 - 0.0069 16.1 0.1 5.7 6.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) OB_RNB PF08206.6 EMC90664.1 - 0.0073 15.7 2.9 3.3 7.2 0.0 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF1464 PF07318.7 EMC90664.1 - 0.18 10.5 1.9 0.61 8.8 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1464) Ank_4 PF13637.1 EMC90665.1 - 1.2e-22 79.8 1.1 2.4e-11 43.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMC90665.1 - 9.8e-19 67.4 0.1 1.8e-12 47.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMC90665.1 - 1.4e-18 65.6 1.8 1.5e-07 30.8 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EMC90665.1 - 1.4e-17 63.3 0.8 1.9e-12 46.9 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC90665.1 - 4.8e-12 44.8 0.2 0.00056 19.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat DUF2795 PF11387.3 EMC90665.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) TPR_11 PF13414.1 EMC90666.1 - 4.2e-59 196.1 26.3 2.9e-16 58.8 0.1 6.3 3 3 4 7 7 7 7 TPR repeat TPR_1 PF00515.23 EMC90666.1 - 6.2e-50 164.8 21.4 3.5e-06 26.3 0.1 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMC90666.1 - 9.7e-39 128.1 11.3 0.00084 19.0 0.0 9.6 8 1 1 9 9 9 9 Tetratricopeptide repeat RPAP3_C PF13877.1 EMC90666.1 - 2.6e-17 62.5 0.0 8.4e-17 60.9 0.0 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.1 EMC90666.1 - 9.9e-17 59.4 17.7 0.0023 17.5 0.1 8.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMC90666.1 - 1.8e-16 59.8 15.1 2.7e-05 24.0 0.2 6.4 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMC90666.1 - 3.2e-16 58.9 4.9 1.3e-05 24.9 0.0 5.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMC90666.1 - 6.4e-16 58.5 0.4 3.4e-05 24.3 0.0 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMC90666.1 - 1.5e-12 47.6 6.8 0.047 14.0 0.0 6.0 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMC90666.1 - 1.3e-11 44.0 0.3 0.18 12.5 0.0 6.7 3 2 4 7 7 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMC90666.1 - 2.3e-09 36.9 14.0 0.034 14.0 0.1 6.3 5 3 3 8 8 7 4 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EMC90666.1 - 6.1e-09 35.0 13.2 0.41 10.5 0.0 8.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMC90666.1 - 1.9e-07 30.7 10.9 0.45 10.8 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMC90666.1 - 0.001 19.3 12.3 0.84 10.2 0.1 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMC90666.1 - 0.0028 17.5 0.2 3.1 7.8 0.1 4.6 5 0 0 5 5 3 1 Tetratricopeptide repeat MIT PF04212.13 EMC90666.1 - 0.015 15.1 8.8 3.3 7.6 0.3 5.5 4 1 2 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EMC90666.1 - 0.048 13.7 0.1 0.048 13.7 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DNA_RNApol_7kD PF03604.8 EMC90667.1 - 5.8e-18 64.0 8.9 8.3e-18 63.5 6.2 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 EMC90667.1 - 0.0012 18.2 1.0 0.0023 17.3 0.7 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain HypA PF01155.14 EMC90667.1 - 0.008 15.8 2.6 0.012 15.2 1.8 1.3 1 1 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EMC90667.1 - 0.0088 15.8 2.6 0.012 15.3 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon Cytochrome_C7 PF14522.1 EMC90667.1 - 0.0098 15.5 0.5 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c7 zf-CHY PF05495.7 EMC90667.1 - 0.043 13.9 3.3 0.076 13.1 2.3 1.3 1 1 0 1 1 1 0 CHY zinc finger zf-ISL3 PF14690.1 EMC90667.1 - 0.056 13.4 1.3 0.056 13.4 0.9 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Mu-like_Com PF10122.4 EMC90667.1 - 0.13 11.3 5.7 0.51 9.4 0.0 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com DUF2082 PF09855.4 EMC90667.1 - 0.14 12.0 0.7 0.14 12.0 0.5 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_5 PF13719.1 EMC90667.1 - 0.22 11.1 2.5 3.3 7.3 1.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMC90667.1 - 0.23 11.1 2.8 5 6.9 2.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EMC90667.1 - 0.72 10.1 5.6 2.6 8.3 2.3 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2296 PF10058.4 EMC90667.1 - 0.98 9.2 3.6 5.7 6.7 2.5 2.0 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Ribosomal_L44 PF00935.14 EMC90667.1 - 1.1 9.3 5.6 12 6.0 2.2 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Ribosomal_L37e PF01907.14 EMC90667.1 - 3.3 7.5 5.6 4.9 7.0 3.9 1.4 1 1 0 1 1 1 0 Ribosomal protein L37e RRN7 PF11781.3 EMC90667.1 - 4.3 6.9 6.8 12 5.5 0.3 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 EMC90667.1 - 4.9 6.8 7.0 15 5.2 2.8 2.4 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger IBR PF01485.16 EMC90668.1 - 1.8e-07 30.9 5.4 1.8e-07 30.9 3.7 2.0 2 0 0 2 2 2 1 IBR domain RGS PF00615.14 EMC90669.1 - 1.2e-08 35.0 0.1 1.5e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain HHH_3 PF12836.2 EMC90669.1 - 0.0033 17.3 0.0 0.016 15.1 0.0 2.0 2 1 0 2 2 2 1 Helix-hairpin-helix motif COX6C PF02937.10 EMC90670.1 - 2.4e-35 120.2 0.6 2.6e-35 120.1 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc HPD PF05044.7 EMC90671.1 - 0.037 13.6 0.1 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Homeo-prospero domain Fe_hyd_SSU PF02256.12 EMC90671.1 - 0.091 12.7 0.1 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Iron hydrogenase small subunit Pkinase PF00069.20 EMC90672.1 - 5.2e-71 238.8 0.0 8.7e-71 238.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90672.1 - 4.2e-53 180.0 1.7 8e-53 179.1 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Mst1_SARAH PF11629.3 EMC90672.1 - 4.3e-27 93.6 3.6 1.5e-26 91.9 2.5 2.0 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Kinase-like PF14531.1 EMC90672.1 - 0.02 13.8 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Kinase-like NAP PF00956.13 EMC90672.1 - 0.59 9.2 11.9 0.089 11.9 0.4 2.9 3 0 0 3 3 3 0 Nucleosome assembly protein (NAP) BTB_2 PF02214.17 EMC90673.1 - 1.1e-31 108.9 0.3 1.8e-30 104.9 0.1 2.5 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 EMC90673.1 - 6.1e-27 94.1 13.5 6.6e-27 94.0 4.2 2.5 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.11 EMC90673.1 - 8.9e-13 47.7 3.7 8.9e-13 47.7 2.6 2.0 2 0 0 2 2 2 1 Ion channel Col_cuticle_N PF01484.12 EMC90673.1 - 7.8 6.2 13.1 9 6.0 0.0 3.4 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Mg_trans_NIPA PF05653.9 EMC90674.1 - 7.7e-93 310.7 23.7 8.8e-93 310.5 16.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EMC90674.1 - 0.00021 21.3 6.7 0.00021 21.3 4.6 3.1 2 2 1 3 3 3 1 EamA-like transporter family DUF872 PF05915.7 EMC90674.1 - 0.47 10.3 0.0 0.47 10.3 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF4131 PF13567.1 EMC90674.1 - 0.6 9.4 22.0 0.44 9.9 3.8 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Ribonuc_L-PSP PF01042.16 EMC90676.1 - 1.2e-42 144.5 0.1 1.3e-42 144.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribosomal_L7Ae PF01248.21 EMC90677.1 - 4.2e-27 93.5 0.1 4.7e-27 93.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.1 EMC90677.1 - 0.032 14.1 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2802 PF10975.3 EMC90677.1 - 0.046 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Mtp PF03821.11 EMC90678.1 - 1.3e-22 80.3 12.3 2.1e-22 79.6 8.6 1.3 1 1 0 1 1 1 1 Golgi 4-transmembrane spanning transporter ABC2_membrane_2 PF12679.2 EMC90678.1 - 0.22 10.3 9.3 0.049 12.4 2.7 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Tetraspannin PF00335.15 EMC90678.1 - 3.1 7.0 14.1 25 4.0 8.3 2.1 1 1 0 1 1 1 0 Tetraspanin family DUF983 PF06170.7 EMC90678.1 - 8.3 6.6 9.6 0.5 10.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF4006 PF13179.1 EMC90680.1 - 0.12 11.9 0.2 0.72 9.4 0.1 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PA PF02225.17 EMC90681.1 - 0.00075 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 PA domain Syndecan PF01034.15 EMC90682.1 - 2e-33 113.8 0.0 3.4e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.6 EMC90682.1 - 0.01 15.4 1.7 0.079 12.5 0.1 2.2 1 1 1 2 2 2 0 Protocadherin Herpes_gE PF02480.11 EMC90682.1 - 0.016 13.5 0.0 0.021 13.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Plasmodium_Vir PF05795.6 EMC90682.1 - 0.039 13.1 0.1 0.045 12.9 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glycophorin_A PF01102.13 EMC90682.1 - 0.16 11.7 8.7 2.7 7.7 5.5 2.2 1 1 1 2 2 2 0 Glycophorin A MtrF PF09472.5 EMC90682.1 - 0.56 9.4 2.6 0.85 8.8 1.8 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TGF_beta_GS PF08515.7 EMC90682.1 - 2.9 7.3 4.8 0.6 9.4 0.9 1.7 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif PSS PF03034.10 EMC90683.1 - 1e-108 363.0 22.9 1e-108 363.0 15.8 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase Peptidase_C1 PF00112.18 EMC90683.1 - 0.038 13.8 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Papain family cysteine protease DUF2393 PF09624.5 EMC90683.1 - 0.27 10.7 2.8 1.2 8.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) DUF1516 PF07457.6 EMC90683.1 - 0.41 10.7 5.2 2.9 8.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DUF2207 PF09972.4 EMC90683.1 - 2.9 6.3 6.1 8.6 4.8 1.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) mTERF PF02536.9 EMC90684.1 - 1.1e-26 93.2 1.8 8.9e-15 54.1 0.2 2.3 1 1 1 2 2 2 2 mTERF UCR_14kD PF02271.11 EMC90685.1 - 3.4e-40 136.0 1.6 4e-40 135.8 1.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DDOST_48kD PF03345.9 EMC90685.1 - 0.1 11.1 0.1 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta RMP PF14996.1 EMC90686.1 - 5.2e-47 159.4 6.1 5.7e-47 159.2 4.2 1.0 1 0 0 1 1 1 1 Retinal Maintenance Allantoicase PF03561.10 EMC90686.1 - 0.023 14.1 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Allantoicase repeat FYVE PF01363.16 EMC90687.1 - 7.8e-20 70.5 7.6 1.9e-19 69.2 5.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EMC90687.1 - 4.6e-12 46.0 0.1 9.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 EMC90687.1 - 0.00061 19.6 5.1 0.0011 18.8 3.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-DHHC PF01529.15 EMC90687.1 - 0.041 13.2 2.2 0.069 12.5 1.5 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase PH_11 PF15413.1 EMC90687.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-UDP PF14569.1 EMC90687.1 - 3.1 7.6 9.6 4.9 6.9 2.2 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger DZR PF12773.2 EMC90687.1 - 4.1 7.3 11.2 14 5.5 4.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon SQS_PSY PF00494.14 EMC90688.1 - 3.3e-50 170.8 0.5 3.9e-50 170.6 0.4 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase DOR PF14839.1 EMC90689.1 - 1.8e-80 269.7 0.4 2e-80 269.5 0.2 1.0 1 0 0 1 1 1 1 DOR family Cyclin_N PF00134.18 EMC90690.1 - 8.5e-40 135.2 1.7 1.8e-39 134.2 1.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMC90690.1 - 5.3e-12 45.7 0.1 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain TPR_8 PF13181.1 EMC90691.1 - 0.00095 18.7 0.5 0.18 11.6 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC90691.1 - 0.0012 18.6 6.4 0.23 11.4 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMC90691.1 - 0.016 14.9 0.4 2.6 8.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMC90691.1 - 0.25 11.0 10.3 2.6 7.8 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Cadherin PF00028.12 EMC90692.1 - 2.3e-211 684.8 23.5 1.2e-21 76.7 0.0 15.3 15 0 0 15 15 15 14 Cadherin domain Cadherin_C PF01049.12 EMC90692.1 - 3e-39 134.4 0.2 8.4e-39 132.9 0.2 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.19 EMC90692.1 - 1.2e-36 125.6 2.3 2.3e-20 72.9 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 EMC90692.1 - 3e-25 88.7 0.1 2.5e-11 43.6 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain Cadherin_pro PF08758.6 EMC90692.1 - 2.1e-13 49.8 0.0 4.2e-05 23.2 0.0 8.6 9 0 0 9 9 9 1 Cadherin prodomain like EGF PF00008.22 EMC90692.1 - 2.8e-11 43.1 49.2 7e-06 25.8 5.3 5.0 4 0 0 4 4 4 4 EGF-like domain Cadherin_2 PF08266.7 EMC90692.1 - 1e-07 31.3 0.0 0.57 9.7 0.0 6.5 6 0 0 6 6 6 2 Cadherin-like Y_Y_Y PF07495.8 EMC90692.1 - 1.1e-06 28.2 2.3 0.15 11.8 0.0 5.1 4 0 0 4 4 4 2 Y_Y_Y domain EGF_2 PF07974.8 EMC90692.1 - 0.00033 20.7 10.2 0.00033 20.7 7.1 4.4 4 0 0 4 4 4 3 EGF-like domain Big_3_4 PF13754.1 EMC90692.1 - 0.072 13.4 0.1 0.072 13.4 0.0 8.1 11 0 0 11 11 11 0 Bacterial Ig-like domain (group 3) RRM_6 PF14259.1 EMC90693.1 - 8.4e-48 160.2 0.0 4.2e-16 58.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC90693.1 - 3.4e-16 58.6 0.0 0.00033 20.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC90693.1 - 2.1e-07 30.6 0.1 0.068 13.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4283 PF14111.1 EMC90693.1 - 0.0014 17.7 0.1 0.13 11.3 0.0 3.8 4 1 0 5 5 5 1 Domain of unknown function (DUF4283) zf-TRAF PF02176.13 EMC90694.1 - 2.3e-08 34.2 4.1 2.3e-08 34.2 2.8 3.2 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.20 EMC90694.1 - 1e-07 31.5 7.5 1e-07 31.5 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EMC90694.1 - 2.5e-07 30.5 10.4 9.4e-05 22.1 2.1 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-RING_2 PF13639.1 EMC90694.1 - 3e-07 30.1 8.2 3e-07 30.1 5.7 2.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EMC90694.1 - 9.8e-07 28.5 6.1 9.8e-07 28.5 4.3 2.7 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMC90694.1 - 1.6e-05 24.8 7.6 1.6e-05 24.8 5.3 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMC90694.1 - 3.3e-05 23.4 3.5 3.3e-05 23.4 2.4 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMC90694.1 - 0.00046 19.9 1.8 0.00046 19.9 1.2 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMC90694.1 - 0.0012 18.5 4.9 0.0033 17.1 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMC90694.1 - 0.0013 18.3 5.6 0.0013 18.3 3.9 2.3 2 1 0 2 2 1 1 zinc-RING finger domain Fzo_mitofusin PF04799.8 EMC90694.1 - 0.096 12.0 4.1 0.17 11.2 2.8 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF3552 PF12072.3 EMC90694.1 - 0.11 11.7 11.3 0.15 11.2 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) IL12p40_C PF10420.4 EMC90694.1 - 0.59 10.2 6.4 1.5 8.9 4.4 1.9 1 1 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus DUF1664 PF07889.7 EMC90694.1 - 0.68 9.7 4.5 1.2 8.8 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF904 PF06005.7 EMC90694.1 - 1.1 9.6 11.3 0.42 10.9 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Defensin_4 PF07936.7 EMC90694.1 - 1.7 8.3 5.9 6.3 6.5 0.5 2.5 2 0 0 2 2 2 0 Potassium-channel blocking toxin OmpH PF03938.9 EMC90694.1 - 3.9 7.3 7.7 6 6.7 5.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ras PF00071.17 EMC90695.1 - 2.9e-31 108.0 0.0 6.9e-31 106.8 0.0 1.6 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EMC90695.1 - 5.3e-20 72.0 0.0 1.3e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EMC90695.1 - 0.00012 21.3 0.1 0.00066 18.9 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 EMC90695.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EMC90695.1 - 0.0018 18.4 0.1 0.51 10.4 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EMC90695.1 - 0.0019 18.2 0.3 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EMC90695.1 - 0.0024 17.7 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMC90695.1 - 0.0059 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMC90695.1 - 0.06 14.1 1.1 0.17 12.6 0.8 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMC90695.1 - 0.1 12.2 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EMC90695.1 - 0.11 12.0 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Cadherin PF00028.12 EMC90696.1 - 1.5e-63 211.0 16.4 3.5e-14 52.8 0.1 7.2 7 0 0 7 7 7 7 Cadherin domain Big_3_4 PF13754.1 EMC90696.1 - 0.81 10.0 11.5 8.3 6.8 0.4 5.2 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 3) PP2C PF00481.16 EMC90697.1 - 3e-37 128.3 0.0 2.8e-36 125.2 0.0 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C Rod_C PF10493.4 EMC90697.1 - 0.0092 14.3 0.0 0.013 13.8 0.0 1.1 1 0 0 1 1 1 1 Rough deal protein C-terminal region Meckelin PF09773.4 EMC90698.1 - 0 1019.5 13.4 0 1019.1 9.3 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Phage_tail_X PF05489.7 EMC90698.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X RRM_6 PF14259.1 EMC90699.1 - 1.8e-55 184.7 0.2 1e-12 47.8 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMC90699.1 - 1.1e-33 114.6 0.1 6.4e-06 25.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC90699.1 - 7.1e-11 41.8 0.0 0.082 12.7 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM92 PF06730.6 EMC90700.1 - 2.2e-108 360.6 10.7 2.5e-108 360.4 7.4 1.0 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.13 EMC90700.1 - 0.00015 21.4 6.2 0.00023 20.7 4.0 1.4 1 1 0 1 1 1 1 BAR domain P4Ha_N PF08336.6 EMC90700.1 - 0.0026 17.5 1.1 0.0026 17.5 0.8 2.0 1 1 1 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Vps5 PF09325.5 EMC90700.1 - 0.0036 16.5 7.0 0.12 11.5 4.9 2.7 1 1 0 1 1 1 1 Vps5 C terminal like HAUS-augmin3 PF14932.1 EMC90700.1 - 0.03 13.5 5.6 0.027 13.6 2.9 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 HTH_42 PF06224.7 EMC90700.1 - 0.032 13.5 0.3 0.048 12.9 0.2 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Band_3_cyto PF07565.8 EMC90700.1 - 0.78 9.2 4.2 1.3 8.4 2.7 1.6 1 1 1 2 2 2 0 Band 3 cytoplasmic domain NinG PF05766.7 EMC90700.1 - 1.4 8.6 4.0 0.51 10.0 0.2 2.1 2 1 1 3 3 3 0 Bacteriophage Lambda NinG protein TRIQK PF15168.1 EMC90701.1 - 1.5e-42 143.3 0.6 1.7e-42 143.2 0.4 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family Wbp11 PF09429.5 EMC90701.1 - 0.088 12.8 1.2 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 CoxIIa PF08113.6 EMC90701.1 - 0.29 10.8 3.2 0.43 10.3 2.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family DDE_1 PF03184.14 EMC90702.1 - 1.2e-19 70.3 0.0 2e-19 69.5 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease NHR2 PF08788.6 EMC90703.1 - 2.8e-39 132.4 8.6 8.9e-39 130.8 6.0 1.9 1 0 0 1 1 1 1 NHR2 domain like TAFH PF07531.9 EMC90703.1 - 6.5e-35 118.6 0.9 1.2e-34 117.7 0.6 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF zf-MYND PF01753.13 EMC90703.1 - 8.9e-08 31.8 18.4 8.9e-08 31.8 12.7 2.1 2 0 0 2 2 2 1 MYND finger DUF3731 PF12531.3 EMC90703.1 - 0.12 11.8 4.5 0.043 13.3 1.1 1.7 2 0 0 2 2 2 0 DNA-K related protein vATP-synt_E PF01991.13 EMC90703.1 - 0.64 9.2 12.3 1 8.5 8.6 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ATP-synt_B PF00430.13 EMC90703.1 - 9.2 6.0 13.0 19 5.0 9.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Tmemb_55A PF09788.4 EMC90704.1 - 2.2e-105 351.4 18.1 2.4e-105 351.3 12.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A PhnA_Zn_Ribbon PF08274.7 EMC90704.1 - 0.0023 17.6 1.2 7.3 6.4 0.3 3.7 3 1 0 3 3 3 1 PhnA Zinc-Ribbon zf-CHY PF05495.7 EMC90704.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.9 2 1 0 2 2 2 0 CHY zinc finger zf-BED PF02892.10 EMC90704.1 - 0.29 10.9 13.4 0.54 10.0 0.0 4.0 3 1 2 5 5 5 0 BED zinc finger IBR PF01485.16 EMC90704.1 - 0.32 10.9 20.4 1.3 8.9 0.2 3.8 2 1 2 4 4 4 0 IBR domain Zn-ribbon_8 PF09723.5 EMC90704.1 - 0.33 10.9 0.2 0.33 10.9 0.2 3.0 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EMC90704.1 - 0.36 10.4 0.0 0.36 10.4 0.0 4.8 5 1 1 6 6 6 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMC90704.1 - 0.36 10.5 0.0 0.36 10.5 0.0 4.8 5 1 1 6 6 6 0 zinc-ribbon domain zf-RING_3 PF14369.1 EMC90704.1 - 1.8 8.6 0.0 1.8 8.6 0.0 3.7 4 0 0 4 4 4 0 zinc-finger eIF_4EBP PF05456.6 EMC90705.1 - 0.019 14.6 0.1 0.02 14.6 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) EF-hand_6 PF13405.1 EMC90706.1 - 7.4e-24 81.4 8.9 2e-07 30.3 0.4 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.27 EMC90706.1 - 3.5e-23 79.0 10.0 1.3e-07 30.4 0.7 5.3 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EMC90706.1 - 1.9e-21 75.9 7.1 2.2e-10 40.5 1.5 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EMC90706.1 - 2.1e-14 52.0 7.9 0.00019 20.6 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EMC90706.1 - 1.5e-08 34.0 9.3 2.9e-06 26.8 0.5 3.2 4 1 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMC90706.1 - 0.0016 18.4 2.9 1.1 9.3 0.0 3.2 2 1 2 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region DUF4299 PF14132.1 EMC90706.1 - 0.0029 16.7 1.0 0.0069 15.5 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4299) EF-hand_like PF09279.6 EMC90706.1 - 0.0075 16.2 7.9 1.1 9.3 0.1 3.5 3 2 0 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_3 PF09069.6 EMC90706.1 - 0.0093 16.0 0.2 1 9.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand LXG PF04740.7 EMC90706.1 - 0.012 15.3 4.9 0.58 9.9 0.5 2.9 2 1 1 3 3 3 0 LXG domain of WXG superfamily EF-hand_10 PF14788.1 EMC90706.1 - 0.028 14.0 9.4 2.1 8.0 0.3 4.3 3 1 1 4 4 4 0 EF hand UPF0158 PF03682.8 EMC90706.1 - 0.06 12.9 4.2 0.22 11.1 0.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0158) EF-hand_9 PF14658.1 EMC90706.1 - 0.12 12.3 0.1 31 4.5 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain RE_Eco47II PF09553.5 EMC90706.1 - 0.18 10.8 2.7 5.6 6.0 0.2 2.4 2 0 0 2 2 2 0 Eco47II restriction endonuclease SYCE1 PF15233.1 EMC90706.1 - 4.3 7.2 8.8 1.4e+02 2.3 6.1 2.4 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 adh_short_C2 PF13561.1 EMC90707.1 - 5.2e-26 91.8 0.3 7e-26 91.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMC90707.1 - 9.9e-20 71.1 2.1 1.4e-19 70.6 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMC90707.1 - 1.3e-07 31.4 0.4 2e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMC90707.1 - 3.2e-05 23.4 0.2 4.8e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMC90707.1 - 0.002 16.9 0.2 0.0029 16.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMC90707.1 - 0.0062 16.9 0.7 0.014 15.8 0.5 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AA_permease_2 PF13520.1 EMC90708.1 - 7.5e-65 219.1 37.9 9.2e-65 218.8 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC90708.1 - 1.1e-30 106.4 29.6 1.1e-30 106.4 20.5 1.3 1 1 0 1 1 1 1 Amino acid permease Copine PF07002.11 EMC90709.1 - 1e-61 206.9 0.1 2.1e-61 205.9 0.0 1.5 2 0 0 2 2 2 1 Copine C2 PF00168.25 EMC90709.1 - 5.5e-29 99.8 0.7 2.8e-15 55.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EMC90709.1 - 3.3e-09 36.8 0.0 9.8e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 vWA found in TerF C terminus TPR_17 PF13431.1 EMC90710.1 - 1e-08 34.6 1.2 0.24 11.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMC90710.1 - 2.9e-07 30.9 3.7 0.11 13.1 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMC90710.1 - 5e-07 29.0 12.2 0.72 9.5 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMC90710.1 - 1.7e-06 27.5 8.2 0.1 12.2 0.5 4.3 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.1 EMC90710.1 - 1.4e-05 25.3 3.9 0.031 14.5 0.4 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMC90710.1 - 1.9e-05 24.1 16.0 1.2 9.1 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMC90710.1 - 0.0003 21.1 4.4 56 4.7 0.9 5.3 3 2 2 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.17 EMC90710.1 - 0.025 13.9 0.1 0.15 11.4 0.1 2.5 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_12 PF13424.1 EMC90710.1 - 0.067 13.1 6.8 0.85 9.6 0.2 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMC90710.1 - 0.48 10.3 12.0 1 9.3 0.7 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat HECT PF00632.20 EMC90711.1 - 6.7e-95 317.8 0.5 1e-94 317.2 0.4 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMC90711.1 - 2e-47 158.6 33.1 5e-13 48.6 2.2 4.5 4 0 0 4 4 4 4 WW domain C2 PF00168.25 EMC90711.1 - 1.5e-08 34.3 0.1 3.1e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 C2 domain Carb_anhydrase PF00194.16 EMC90712.1 - 4.9e-121 402.5 0.0 5.6e-121 402.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 EMC90713.1 - 4.8e-97 323.9 0.0 5.5e-96 320.4 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 EMC90714.1 - 3.3e-102 340.8 0.0 3.7e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 EMC90715.1 - 1.1e-46 158.8 0.1 1.3e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 EMC90716.1 - 2.8e-110 367.3 0.0 3.1e-110 367.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase E2F_TDP PF02319.15 EMC90717.1 - 7.4e-15 54.2 0.3 1.4e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LRR_4 PF12799.2 EMC90718.1 - 3.7e-19 67.8 18.8 1.5e-09 37.2 1.0 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMC90718.1 - 8.8e-11 41.3 24.7 1.1e-05 25.0 1.6 3.8 2 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 EMC90718.1 - 1.6e-08 34.3 8.7 1.1e-05 25.0 0.5 3.3 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 EMC90718.1 - 1.8e-06 27.4 20.6 0.0034 17.2 0.1 5.9 3 1 3 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 EMC90718.1 - 0.00036 20.1 23.6 0.18 11.9 0.4 5.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EMC90718.1 - 0.0012 18.7 15.3 1 9.8 0.3 5.9 5 0 0 5 5 5 2 Leucine rich repeat AA_permease_2 PF13520.1 EMC90719.1 - 1.4e-56 191.8 41.6 1.7e-56 191.5 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMC90719.1 - 1.1e-23 83.3 37.8 1.4e-23 82.9 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease TRIQK PF15168.1 EMC90719.1 - 0.089 12.7 0.1 0.38 10.6 0.0 2.1 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family SR-25 PF10500.4 EMC90720.1 - 0.0037 16.7 4.5 0.0047 16.4 3.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Muted PF14942.1 EMC90720.1 - 0.011 15.6 3.0 0.016 15.0 2.1 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Alpha-2-MRAP_C PF06401.6 EMC90720.1 - 0.017 14.9 1.9 0.025 14.4 1.3 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain RP-C_C PF11800.3 EMC90720.1 - 0.024 14.3 2.6 0.03 14.0 1.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4407 PF14362.1 EMC90720.1 - 0.058 12.3 2.6 0.069 12.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.4 EMC90720.1 - 0.059 13.2 7.0 0.1 12.5 4.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Fmp27_WPPW PF10359.4 EMC90720.1 - 0.063 11.6 2.0 0.068 11.5 1.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BUD22 PF09073.5 EMC90720.1 - 0.13 11.3 11.3 0.15 11.0 7.8 1.1 1 0 0 1 1 1 0 BUD22 MCLC PF05934.6 EMC90720.1 - 0.13 10.4 2.1 0.18 10.0 1.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Mnd1 PF03962.10 EMC90720.1 - 0.41 10.2 7.1 0.59 9.7 4.9 1.1 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 EMC90720.1 - 0.7 8.8 6.4 0.88 8.5 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4611 PF15387.1 EMC90720.1 - 4 7.6 15.4 0.069 13.3 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) RRM_1 PF00076.17 EMC90721.1 - 1e-10 41.0 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMC90721.1 - 3.7e-07 30.0 0.0 5.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMC90721.1 - 3.5e-05 23.5 0.3 6.3e-05 22.7 0.1 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMC90721.1 - 0.049 13.4 0.3 0.13 12.0 0.1 1.7 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif PX PF00787.19 EMC90722.1 - 2.9e-19 68.9 1.1 3.8e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 PX domain DUF641 PF04859.7 EMC90722.1 - 0.022 14.5 0.4 0.05 13.3 0.2 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Lip_prot_lig_C PF10437.4 EMC90722.1 - 0.13 11.9 0.0 25 4.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus IncA PF04156.9 EMC90722.1 - 0.17 11.4 3.0 0.29 10.6 2.1 1.3 1 0 0 1 1 1 0 IncA protein Snf7 PF03357.16 EMC90724.1 - 3.8e-43 146.8 10.6 5.5e-43 146.3 7.3 1.2 1 0 0 1 1 1 1 Snf7 Glyco_hydro_65m PF03632.10 EMC90724.1 - 0.039 12.6 0.7 0.047 12.3 0.5 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Trns_repr_metal PF02583.12 EMC90724.1 - 0.13 12.4 2.2 0.25 11.5 1.5 1.5 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor TBPIP PF07106.8 EMC90724.1 - 0.29 10.6 9.7 0.44 10.0 2.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-AN1 PF01428.11 EMC90725.1 - 3.6e-19 68.3 24.7 5.2e-10 39.0 9.3 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger EndoU_bacteria PF14436.1 EMC90725.1 - 0.0096 15.7 0.4 0.06 13.1 0.3 2.0 1 1 1 2 2 2 1 Bacterial EndoU nuclease Lipocalin PF00061.18 EMC90726.1 - 1.2e-26 93.4 3.1 1.3e-26 93.3 2.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 EMC90726.1 - 0.00083 19.0 2.4 0.0011 18.6 1.6 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 EMC90727.1 - 5.2e-26 91.3 1.0 5.7e-26 91.2 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 EMC90727.1 - 5e-06 26.2 1.6 7.8e-06 25.6 1.1 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Toxin_56 PF15534.1 EMC90727.1 - 0.14 12.6 0.9 0.78 10.2 0.2 2.0 2 0 0 2 2 2 0 Putative toxin 56 Lipocalin PF00061.18 EMC90728.1 - 1.5e-07 31.5 0.3 1.5e-07 31.5 0.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PhnA PF03831.9 EMC90728.1 - 0.093 12.1 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 PhnA protein MRP_L53 PF10780.4 EMC90729.1 - 7.2e-14 51.4 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Ank PF00023.25 EMC90730.1 - 3.6e-29 99.0 2.4 6.8e-06 25.6 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EMC90730.1 - 3e-28 97.9 0.2 4.6e-13 49.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMC90730.1 - 1.5e-22 79.5 3.4 1.6e-09 38.0 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMC90730.1 - 9.8e-20 70.1 5.1 9.1e-07 28.9 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMC90730.1 - 4.5e-19 66.6 0.9 0.0017 18.4 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat 7tm_1 PF00001.16 EMC90731.1 - 1.7e-34 119.1 19.9 2e-34 118.8 13.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sushi PF00084.15 EMC90732.1 - 4.7e-20 71.6 5.9 1.1e-09 38.4 0.4 2.2 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Dus PF01207.12 EMC90733.1 - 1.8e-55 187.9 0.0 2.5e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EMC90733.1 - 0.0029 17.2 15.7 0.023 14.3 0.9 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PEP_mutase PF13714.1 EMC90733.1 - 0.0058 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase FMN_dh PF01070.13 EMC90733.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase VIT PF08487.5 EMC90734.1 - 1.6e-13 50.3 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 EMC90734.1 - 4.4e-08 32.4 0.1 6.7e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Calcipressin PF04847.7 EMC90736.1 - 7.3e-56 188.6 0.4 8.4e-56 188.4 0.3 1.0 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 EMC90736.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMC90736.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 FAM74 PF15026.1 EMC90737.1 - 1.8 8.2 10.2 0.15 11.6 2.9 1.9 2 0 0 2 2 2 0 FAM74 protein Nop53 PF07767.6 EMC90737.1 - 1.9 7.4 33.7 2.6 6.9 23.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) 7tm_1 PF00001.16 EMC90738.1 - 5.2e-34 117.5 34.2 1.2e-33 116.4 23.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YWFCY PF14293.1 EMC90738.1 - 0.43 10.4 8.7 2.2 8.1 0.1 3.2 3 0 0 3 3 3 0 YWFCY protein VWD PF00094.20 EMC90739.1 - 5.9e-16 59.0 0.2 6.5e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain BAAT_C PF08840.6 EMC90740.1 - 2.5e-71 239.7 0.0 3e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EMC90740.1 - 0.0034 16.7 0.4 0.026 13.8 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMC90740.1 - 0.0049 16.6 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMC90740.1 - 0.006 15.8 0.0 0.021 14.0 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EMC90740.1 - 0.0076 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMC90740.1 - 0.031 14.1 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family RepB-RCR_reg PF10723.4 EMC90742.1 - 0.051 13.3 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Replication regulatory protein RepB Trypsin PF00089.21 EMC90744.1 - 3e-24 85.8 0.0 3.2e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin HCaRG PF07258.9 EMC90745.1 - 5.2e-05 22.8 1.0 8e-05 22.2 0.4 1.5 1 1 0 1 1 1 1 HCaRG protein BLOC1_2 PF10046.4 EMC90745.1 - 0.073 13.2 0.2 0.086 12.9 0.1 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 p450 PF00067.17 EMC90746.1 - 2.6e-26 92.1 0.1 2.9e-26 92.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Njmu-R1 PF15053.1 EMC90746.1 - 0.014 14.2 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family MNE1 PF13762.1 EMC90746.1 - 0.015 15.4 0.1 0.044 13.8 0.0 1.8 1 1 0 1 1 1 0 Mitochondrial splicing apparatus component PDEase_I PF00233.14 EMC90748.1 - 3e-36 125.3 4.0 3.5e-36 125.1 2.8 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-H2C2_2 PF13465.1 EMC90749.1 - 4.1e-07 29.9 7.7 5.2e-05 23.3 0.8 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90749.1 - 0.0011 19.1 6.1 0.0014 18.8 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90749.1 - 0.0041 17.3 4.4 0.008 16.4 0.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger DUF3133 PF11331.3 EMC90749.1 - 0.016 14.7 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) Mu-like_Com PF10122.4 EMC90749.1 - 0.023 13.7 3.2 0.074 12.1 1.4 2.0 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-C2H2_6 PF13912.1 EMC90749.1 - 0.08 12.8 3.2 0.55 10.2 2.2 2.1 1 1 0 1 1 1 0 C2H2-type zinc finger zf-ISL3 PF14690.1 EMC90749.1 - 0.86 9.6 4.5 1.6 8.7 0.7 1.8 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 MAM PF00629.18 EMC90750.1 - 1.8e-35 122.0 0.0 2e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 MAM domain TLV_coat PF00429.14 EMC90751.1 - 3.4e-06 25.8 0.2 4.2e-06 25.5 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) TraF PF13728.1 EMC90752.1 - 0.014 14.9 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein 7TMR-HDED PF07697.6 EMC90752.1 - 0.021 14.5 0.0 3.5 7.3 0.0 2.1 1 1 1 2 2 2 0 7TM-HD extracellular LRR_8 PF13855.1 EMC90753.1 - 3.1e-20 71.6 15.3 5.3e-16 58.1 6.0 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EMC90753.1 - 2e-13 49.6 20.8 5.8e-07 29.0 5.1 3.1 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC90753.1 - 1.1e-11 43.0 10.0 0.0047 16.7 0.2 4.2 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_9 PF14580.1 EMC90753.1 - 0.00014 21.4 0.1 0.0027 17.2 0.2 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_5 PF13306.1 EMC90753.1 - 0.00094 18.8 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC90753.1 - 0.0031 17.4 12.5 2.5 8.6 0.8 4.5 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EMC90753.1 - 0.0033 17.3 12.9 1.8 8.8 0.2 4.3 3 1 1 4 4 4 3 Leucine Rich repeat LRR_2 PF07723.8 EMC90753.1 - 0.023 15.2 0.3 0.87 10.1 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat Arf PF00025.16 EMC90754.1 - 2.7e-06 26.7 0.0 2.7e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.17 EMC90754.1 - 0.068 12.8 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 EMC90755.1 - 2.3e-32 112.1 0.1 2.5e-32 112.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3216 PF11505.3 EMC90755.1 - 0.087 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) LRR_8 PF13855.1 EMC90756.1 - 1.1e-48 162.7 11.8 3.9e-13 48.9 1.6 5.1 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EMC90756.1 - 1.2e-29 101.3 14.6 4.3e-09 35.8 0.5 5.7 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMC90756.1 - 2.9e-22 75.2 20.0 0.019 14.9 0.0 9.4 10 0 0 10 10 10 7 Leucine Rich Repeat LRR_5 PF13306.1 EMC90756.1 - 1.1e-17 63.9 0.0 4.6e-13 49.0 0.0 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EMC90756.1 - 4.3e-12 44.1 22.8 0.57 10.6 0.0 9.7 10 0 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 EMC90756.1 - 7.6e-08 31.6 11.6 8.1 6.8 0.2 8.2 8 1 1 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.1 EMC90756.1 - 1.4e-07 31.2 1.0 0.0012 18.4 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRRNT PF01462.13 EMC90756.1 - 2.1e-06 27.0 2.4 2.1e-06 27.0 1.6 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain VWD PF00094.20 EMC90757.1 - 1.9e-14 54.1 0.1 2.1e-14 54.0 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain IRF-2BP1_2 PF11261.3 EMC90757.1 - 0.054 12.9 0.6 3.6 7.1 0.3 2.1 1 1 1 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger UDPGT PF00201.13 EMC90758.1 - 4.2e-60 203.7 0.0 4.6e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Transferrin PF00405.12 EMC90760.1 - 2.3e-21 76.0 0.0 2.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Transferrin Chlam_OMP3 PF03503.8 EMC90760.1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Trypsin_2 PF13365.1 EMC90761.1 - 1.3e-05 25.2 0.6 1.7e-05 24.8 0.4 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF2635 PF10948.3 EMC90761.1 - 0.045 13.0 0.3 0.076 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Peptidase_S7 PF00949.16 EMC90761.1 - 0.16 11.3 0.1 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF3421 PF11901.3 EMC90764.1 - 1.2e-17 63.7 0.3 2.4e-16 59.5 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3421) Mesd PF10185.4 EMC90764.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor DUF4496 PF14908.1 EMC90765.1 - 6.9e-10 38.9 0.0 8.6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) p450 PF00067.17 EMC90766.1 - 4.2e-28 98.0 0.8 4.5e-28 97.9 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0546 PF10639.4 EMC90767.1 - 2.3e-16 59.6 0.1 2.4e-16 59.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 CM2 PF03021.9 EMC90767.1 - 0.15 11.5 0.5 0.16 11.5 0.3 1.0 1 0 0 1 1 1 0 Influenza C virus M2 protein TLV_coat PF00429.14 EMC90768.1 - 1.4e-07 30.4 0.7 1.6e-07 30.1 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) WXG100 PF06013.7 EMC90768.1 - 0.34 10.9 3.5 1.1 9.2 1.1 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Epimerase PF01370.16 EMC90769.1 - 2.4e-24 86.0 0.0 2.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMC90769.1 - 3e-08 32.8 0.0 4.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMC90769.1 - 7.5e-06 25.0 0.7 0.00046 19.1 0.0 2.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMC90769.1 - 0.022 13.4 1.3 0.6 8.7 0.9 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMC90769.1 - 0.085 11.7 0.1 3.8 6.3 0.0 2.0 1 1 1 2 2 2 0 Male sterility protein adh_short PF00106.20 EMC90769.1 - 0.15 11.9 2.8 11 5.9 1.1 2.1 1 1 1 2 2 2 0 short chain dehydrogenase KR PF08659.5 EMC90769.1 - 0.62 9.6 2.7 11 5.6 0.4 2.0 1 1 0 2 2 2 0 KR domain cNMP_binding PF00027.24 EMC90770.1 - 9.2e-19 67.0 0.0 1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain VWD PF00094.20 EMC90771.1 - 1.9e-14 54.1 0.3 2e-14 54.0 0.2 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain zf-H2C2_2 PF13465.1 EMC90772.1 - 1.3e-10 40.9 13.2 7.4e-10 38.6 1.1 2.5 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90772.1 - 1.1e-09 38.0 9.5 4e-06 26.8 1.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90772.1 - 2.5e-07 30.5 7.9 9.9e-05 22.4 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMC90772.1 - 4.3e-06 26.2 7.5 0.014 14.9 0.5 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EMC90772.1 - 2.5e-05 24.2 0.2 0.0041 17.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMC90772.1 - 0.016 15.3 2.7 0.034 14.2 1.9 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EMC90772.1 - 0.029 14.3 1.4 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 zinc-finger cEGF PF12662.2 EMC90772.1 - 0.036 13.7 5.2 0.6 9.7 0.3 2.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like LIM PF00412.17 EMC90772.1 - 0.058 13.4 1.0 0.081 13.0 0.7 1.3 1 1 0 1 1 1 0 LIM domain zf-C2H2_2 PF12756.2 EMC90772.1 - 0.13 12.3 1.7 1.5 8.9 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EMC90772.1 - 0.16 11.3 2.9 1.2 8.5 0.3 2.0 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rad50_zn_hook PF04423.9 EMC90772.1 - 0.27 10.7 3.2 1.7 8.1 0.2 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif C1_1 PF00130.17 EMC90772.1 - 0.34 10.6 2.6 3 7.6 1.9 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH PF01844.18 EMC90772.1 - 0.6 10.0 3.6 0.43 10.4 0.2 1.9 2 0 0 2 2 2 0 HNH endonuclease Zn-ribbon_8 PF09723.5 EMC90772.1 - 0.89 9.5 6.7 4.1 7.4 0.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-CHCC PF10276.4 EMC90772.1 - 1.7 8.5 6.9 1.2 9.0 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger domain Zn_Tnp_IS1595 PF12760.2 EMC90772.1 - 3.3 7.5 7.6 10 6.0 5.3 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-AN1 PF01428.11 EMC90772.1 - 4.4 7.2 7.1 6.3 6.7 1.1 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-ISL3 PF14690.1 EMC90772.1 - 5.4 7.1 7.0 8.6 6.4 1.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 MMtag PF10159.4 EMC90773.1 - 1.7e-33 114.5 0.7 2e-33 114.2 0.5 1.1 1 0 0 1 1 1 1 Kinase phosphorylation protein Laminin_EGF PF00053.19 EMC90774.1 - 3.4e-09 36.4 20.1 0.00027 20.8 6.3 2.3 1 1 1 2 2 2 2 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EMC90774.1 - 0.00045 20.1 0.4 0.00045 20.1 0.3 5.2 5 1 0 5 5 5 2 Human growth factor-like EGF EGF_2 PF07974.8 EMC90774.1 - 0.0009 19.3 29.1 0.0025 17.9 6.3 3.2 3 0 0 3 3 3 2 EGF-like domain EB PF01683.13 EMC90774.1 - 0.012 15.6 19.4 0.056 13.5 9.9 2.3 1 1 1 2 2 2 0 EB module cEGF PF12662.2 EMC90774.1 - 0.016 14.8 17.8 0.75 9.4 0.5 3.9 2 1 1 3 3 3 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EMC90774.1 - 2.5 8.2 23.8 13 5.9 0.2 3.2 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site EGF PF00008.22 EMC90774.1 - 2.7 8.0 26.2 26 4.9 14.0 3.6 1 1 2 3 3 3 0 EGF-like domain DSL PF01414.14 EMC90774.1 - 3.5 7.7 21.7 0.76 9.8 1.2 2.1 1 1 1 2 2 2 0 Delta serrate ligand YL1 PF05764.8 EMC90775.1 - 3.2e-24 85.8 5.4 3.6e-24 85.6 3.8 1.0 1 0 0 1 1 1 1 YL1 nuclear protein Cullin_Nedd8 PF10557.4 EMC90776.1 - 1.6e-05 24.5 0.1 0.0002 21.1 0.1 2.1 1 1 0 1 1 1 1 Cullin protein neddylation domain MHC_I PF00129.13 EMC90777.1 - 3.2e-29 101.5 0.6 4.3e-29 101.1 0.4 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.10 EMC90777.1 - 1.5e-19 69.7 0.0 3.9e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 EMC90777.1 - 0.00058 19.9 0.0 0.0034 17.4 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 EMC90777.1 - 0.0066 16.9 0.0 0.022 15.2 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC90777.1 - 0.021 14.6 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin I-set domain zf-H2C2_2 PF13465.1 EMC90778.1 - 1.3e-18 66.2 5.7 1.3e-09 37.8 0.4 2.7 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90778.1 - 8.6e-11 41.5 19.9 1.5e-05 24.9 0.5 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90778.1 - 1.8e-08 34.1 16.1 4e-05 23.6 0.6 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met2 PF12907.2 EMC90778.1 - 0.0048 16.8 0.8 1.5 8.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding C1_1 PF00130.17 EMC90778.1 - 0.014 15.1 0.2 0.024 14.3 0.1 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.2 EMC90778.1 - 0.016 15.0 2.1 0.023 14.5 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_jaz PF12171.3 EMC90778.1 - 0.05 13.7 0.4 0.05 13.7 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GATA PF00320.22 EMC90778.1 - 0.057 12.7 0.9 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 GATA zinc finger Zn-ribbon_8 PF09723.5 EMC90778.1 - 0.091 12.7 2.4 4.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain DUF1644 PF07800.7 EMC90778.1 - 0.11 12.3 2.4 0.13 12.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) DZR PF12773.2 EMC90778.1 - 0.17 11.7 1.3 0.33 10.7 0.9 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_7 PF15269.1 EMC90778.1 - 0.22 11.3 7.5 2.1 8.2 0.6 2.1 1 1 1 2 2 2 0 Zinc-finger zf-CHY PF05495.7 EMC90778.1 - 0.34 11.1 3.4 0.64 10.2 2.4 1.5 1 1 0 1 1 1 0 CHY zinc finger PHD PF00628.24 EMC90778.1 - 0.34 10.6 3.0 0.91 9.2 2.0 1.7 1 1 0 1 1 1 0 PHD-finger zf-DNL PF05180.7 EMC90778.1 - 0.38 10.4 2.5 0.65 9.7 1.7 1.3 1 1 0 1 1 1 0 DNL zinc finger C1_4 PF07975.7 EMC90778.1 - 0.65 10.0 4.6 2.4 8.2 0.1 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 EMC90778.1 - 0.76 9.7 11.1 1.2 9.1 0.6 3.3 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMC90778.1 - 1.5 8.9 6.8 1.9 8.6 0.7 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.14 EMC90778.1 - 1.8 8.7 7.1 22 5.2 5.0 2.2 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2HC_2 PF13913.1 EMC90778.1 - 4 7.2 6.4 0.58 9.8 0.5 2.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-AN1 PF01428.11 EMC90778.1 - 7.8 6.4 8.4 12 5.8 0.3 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger SNF2_N PF00176.18 EMC90779.1 - 0.00025 19.9 0.0 0.00028 19.8 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Neurexophilin PF06312.7 EMC90780.1 - 2.2e-98 327.8 2.0 2.4e-98 327.6 1.4 1.0 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.14 EMC90780.1 - 0.0043 17.6 0.4 0.33 11.5 0.0 2.2 1 1 1 2 2 2 1 Filamin/ABP280 repeat NigD PF12667.2 EMC90780.1 - 0.024 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 NigD-like protein CHORD PF04968.7 EMC90780.1 - 2.8 8.2 8.0 0.98 9.7 3.7 1.7 1 1 1 2 2 2 0 CHORD HSP70 PF00012.15 EMC90781.1 - 3.7e-30 104.4 0.4 4.3e-30 104.2 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.15 EMC90781.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family 7tm_1 PF00001.16 EMC90782.1 - 1.2e-19 70.4 6.2 1.2e-19 70.4 4.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 EMC90782.1 - 2.4e-05 23.6 7.9 2.4e-05 23.6 5.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3814 PF12769.2 EMC90782.1 - 0.39 10.8 9.1 0.056 13.6 3.7 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3814) CytochromB561_N PF09786.4 EMC90782.1 - 1.1 7.6 2.9 1.3 7.4 2.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal tRNA-synt_2b PF00587.20 EMC90783.1 - 0.00069 19.2 0.0 0.0007 19.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.20 EMC90784.1 - 1.5e-06 27.5 0.0 1.6e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMC90784.1 - 0.029 13.4 0.0 0.033 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Hormone_recep PF00104.25 EMC90785.1 - 6.7e-09 35.1 0.0 6.9e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C3HC4_3 PF13920.1 EMC90786.1 - 4.4e-08 32.6 11.1 5.6e-08 32.3 7.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMC90786.1 - 4.8e-07 29.3 14.0 6.6e-07 28.8 9.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMC90786.1 - 3.1e-06 27.0 13.9 4.2e-06 26.6 9.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMC90786.1 - 2.4e-05 23.9 14.7 0.00027 20.5 10.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMC90786.1 - 0.00049 19.8 16.8 0.018 14.8 12.1 2.2 1 1 1 2 2 2 1 Ring finger domain TerY-C PF15616.1 EMC90786.1 - 0.0031 17.4 5.7 0.0041 17.0 4.0 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_6 PF14835.1 EMC90786.1 - 0.0042 16.8 3.2 0.0061 16.3 2.2 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMC90786.1 - 0.005 16.5 7.9 0.008 15.8 5.5 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMC90786.1 - 0.0053 16.8 7.8 0.0053 16.8 5.4 1.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMC90786.1 - 0.0053 16.5 10.6 0.01 15.7 7.4 1.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Endonuclease_7 PF02945.10 EMC90786.1 - 0.012 15.3 3.1 0.014 15.0 2.1 1.1 1 0 0 1 1 1 0 Recombination endonuclease VII zf-Apc11 PF12861.2 EMC90786.1 - 0.048 13.5 5.6 0.066 13.0 3.9 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 EMC90786.1 - 0.11 11.6 2.9 0.11 11.6 2.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-TFIIB PF13453.1 EMC90786.1 - 0.2 10.8 2.9 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-MIZ PF02891.15 EMC90786.1 - 0.84 9.2 12.6 1.8 8.1 8.8 1.6 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger PolC_DP2 PF03833.8 EMC90786.1 - 0.95 7.0 3.1 0.9 7.1 2.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_4 PF13717.1 EMC90786.1 - 4.3 7.1 15.6 1.4 8.6 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EMC90786.1 - 4.7 6.5 13.2 2.6 7.3 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 EMC90786.1 - 5.9 6.9 9.9 11 6.0 2.5 2.7 2 1 0 2 2 2 0 zinc-finger zinc_ribbon_5 PF13719.1 EMC90786.1 - 6.1 6.5 16.2 1.3 8.6 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.1 EMC90786.1 - 6.9 6.3 15.9 31 4.2 11.1 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain UDPGT PF00201.13 EMC90787.1 - 1e-29 103.5 0.1 1.1e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-H2C2_2 PF13465.1 EMC90788.1 - 1.7e-07 31.1 2.7 0.04 14.2 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90788.1 - 5.3e-07 29.6 5.4 2.1e-06 27.7 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90788.1 - 0.00013 22.0 6.1 0.00033 20.7 1.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90788.1 - 0.006 16.6 0.3 0.0085 16.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC90788.1 - 0.19 11.6 2.4 0.65 9.9 1.6 2.0 1 1 0 1 1 1 0 C2H2-type zinc finger V-set PF07686.12 EMC90789.1 - 1.1e-16 60.6 0.0 1.3e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 EMC90789.1 - 3.7e-06 26.9 1.2 2.8e-05 24.1 0.8 2.0 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 EMC90789.1 - 0.00041 20.1 0.0 0.00055 19.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 EMC90789.1 - 0.00086 19.7 0.2 0.0016 18.9 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 EMC90789.1 - 0.0014 18.6 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain KOW PF00467.24 EMC90790.1 - 0.0003 20.4 1.1 0.00044 19.8 0.8 1.3 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 EMC90791.1 - 1.6e-13 50.3 0.0 1.8e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMC90791.1 - 4.6e-06 27.1 0.0 5.1e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Homeobox PF00046.24 EMC90792.1 - 2.2e-17 62.3 0.5 2.4e-17 62.2 0.3 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMC90792.1 - 0.0048 16.5 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain Phage_terminase PF10668.4 EMC90792.1 - 0.096 12.4 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Phage terminase small subunit RNA_pol_Rpb1_5 PF04998.12 EMC90793.1 - 6.5e-06 25.6 0.0 6.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 EMC90793.1 - 0.029 14.1 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Keratin PF02422.11 EMC90794.1 - 4.5e-25 87.4 10.4 4.9e-25 87.3 7.2 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.12 EMC90794.1 - 0.13 12.4 1.8 0.16 12.1 1.3 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain zf-C2H2 PF00096.21 EMC90795.1 - 6.5e-16 57.6 5.0 8.5e-08 32.1 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMC90795.1 - 7.7e-13 48.0 12.8 1.3e-07 31.5 0.4 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMC90795.1 - 1.7e-09 37.3 2.7 0.00095 19.3 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMC90795.1 - 2.4e-07 30.3 7.9 2.4e-05 24.0 0.3 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90795.1 - 0.00013 22.0 1.0 0.055 13.6 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.4 EMC90795.1 - 0.00053 19.6 2.1 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.1 EMC90795.1 - 0.0068 16.0 1.2 0.11 12.1 0.1 2.1 2 0 0 2 2 2 1 Probable zinc-binding domain zf-met PF12874.2 EMC90795.1 - 0.011 15.9 4.9 0.48 10.7 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EMC90795.1 - 0.012 15.2 0.0 0.012 15.2 0.0 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type XPA_N PF01286.13 EMC90795.1 - 0.019 14.5 2.1 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal LIM PF00412.17 EMC90795.1 - 0.02 14.9 1.2 0.027 14.5 0.8 1.2 1 0 0 1 1 1 0 LIM domain Zn_ribbon_recom PF13408.1 EMC90795.1 - 0.052 13.8 1.7 3.8 7.8 0.2 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 EMC90795.1 - 0.069 12.6 0.5 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 EMC90795.1 - 0.073 13.0 1.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 EMC90795.1 - 0.11 12.6 0.9 0.35 11.0 0.7 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 EMC90795.1 - 0.19 11.4 1.1 8 6.2 0.1 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 EMC90795.1 - 0.28 10.9 5.7 7 6.5 3.9 2.2 1 1 0 1 1 1 0 BED zinc finger C1_2 PF03107.11 EMC90795.1 - 0.41 10.8 3.1 6.2 7.0 0.1 2.1 2 0 0 2 2 2 0 C1 domain zinc_ribbon_5 PF13719.1 EMC90795.1 - 0.61 9.7 3.2 8.5 6.0 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF3133 PF11331.3 EMC90795.1 - 0.71 9.4 2.7 6.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) ADK_lid PF05191.9 EMC90795.1 - 0.84 9.3 2.9 4.2 7.1 0.1 2.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.1 EMC90795.1 - 0.98 9.1 3.0 15 5.3 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-AN1 PF01428.11 EMC90795.1 - 6.9 6.6 6.5 4.8 7.1 1.3 2.3 2 1 0 2 2 2 0 AN1-like Zinc finger Dynein_light PF01221.13 EMC90796.1 - 1.1e-30 105.4 0.7 1.2e-30 105.3 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Omptin PF01278.15 EMC90796.1 - 0.052 12.6 0.1 0.057 12.5 0.1 1.0 1 0 0 1 1 1 0 Omptin family Trypsin PF00089.21 EMC90797.1 - 2.2e-17 63.4 3.1 2.4e-17 63.2 2.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 EMC90798.1 - 2.1e-15 56.8 0.8 2.3e-15 56.7 0.5 1.0 1 0 0 1 1 1 1 Trypsin DUF1242 PF06842.7 EMC90799.1 - 1.6e-11 43.4 1.1 1.9e-11 43.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Keratin PF02422.11 EMC90800.1 - 2.7e-30 104.2 6.6 3e-30 104.0 4.6 1.1 1 0 0 1 1 1 1 Keratin EF-hand_4 PF12763.2 EMC90801.1 - 1.1e-12 47.5 0.0 1.4e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EMC90801.1 - 0.00044 19.3 0.0 0.00055 19.0 0.0 1.1 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EMC90801.1 - 0.0081 15.4 0.1 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EMC90801.1 - 0.014 15.5 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EMC90801.1 - 0.041 13.7 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain zf-H2C2_2 PF13465.1 EMC90802.1 - 2.1e-24 84.5 12.1 2.3e-09 37.0 0.5 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90802.1 - 4e-12 45.7 10.2 5.9e-07 29.4 0.9 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMC90802.1 - 2.9e-08 33.3 9.1 1.2e-05 25.0 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMC90802.1 - 9.5e-08 31.8 9.1 2.6e-05 24.2 1.0 3.1 4 0 0 4 4 3 2 C2H2-type zinc finger zf-trcl PF13451.1 EMC90802.1 - 0.00023 20.7 5.2 0.096 12.3 0.0 3.1 3 0 0 3 3 3 1 Probable zinc-binding domain zf-C2H2_jaz PF12171.3 EMC90802.1 - 0.00028 20.9 0.8 0.0075 16.3 0.2 2.6 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMC90802.1 - 0.00048 20.2 6.9 0.16 12.2 1.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-AN1 PF01428.11 EMC90802.1 - 0.0019 18.0 5.8 1.1 9.2 0.1 3.1 3 0 0 3 3 3 2 AN1-like Zinc finger C1_1 PF00130.17 EMC90802.1 - 0.002 17.7 4.1 0.045 13.4 0.5 2.4 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF164 PF02591.10 EMC90802.1 - 0.0027 17.4 2.5 3.1 7.6 0.1 2.9 3 0 0 3 3 3 0 Putative zinc ribbon domain LIM PF00412.17 EMC90802.1 - 0.0042 17.1 7.2 0.27 11.3 2.3 3.0 2 1 1 3 3 3 1 LIM domain zf-C2HC_2 PF13913.1 EMC90802.1 - 0.0047 16.5 5.0 0.31 10.7 0.3 2.6 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-HYPF PF07503.7 EMC90802.1 - 0.012 15.0 7.2 2.3 7.6 0.1 3.2 3 0 0 3 3 3 0 HypF finger zf-ISL3 PF14690.1 EMC90802.1 - 0.018 15.0 8.4 0.18 11.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CHY PF05495.7 EMC90802.1 - 0.026 14.6 4.2 0.04 14.0 2.9 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-LYAR PF08790.6 EMC90802.1 - 0.03 14.0 9.0 0.39 10.4 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger CpXC PF14353.1 EMC90802.1 - 0.047 13.6 3.2 2.3 8.1 0.0 2.4 3 0 0 3 3 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.2 EMC90802.1 - 0.053 13.3 10.0 0.48 10.2 3.0 2.5 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMC90802.1 - 0.055 13.4 10.8 0.49 10.3 2.9 3.1 1 1 1 3 3 3 0 Zinc ribbon domain FYDLN_acid PF09538.5 EMC90802.1 - 0.059 13.9 0.5 11 6.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) HypA PF01155.14 EMC90802.1 - 0.068 12.8 3.4 0.38 10.4 0.7 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C4_ClpX PF06689.8 EMC90802.1 - 0.07 12.6 0.3 0.07 12.6 0.2 2.2 3 0 0 3 3 2 0 ClpX C4-type zinc finger zf-Di19 PF05605.7 EMC90802.1 - 0.082 13.0 6.0 0.32 11.1 0.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sgf11 PF08209.6 EMC90802.1 - 0.085 12.1 5.0 0.52 9.6 0.0 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) ATPase-cat_bd PF12156.3 EMC90802.1 - 0.087 13.3 3.3 0.087 13.3 2.3 1.9 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase DNA_RNApol_7kD PF03604.8 EMC90802.1 - 0.092 12.2 3.2 19 4.8 0.0 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.1 EMC90802.1 - 0.097 12.4 2.8 3.5 7.4 0.8 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_5 PF13719.1 EMC90802.1 - 0.12 12.0 7.8 3.5 7.2 2.4 3.0 1 1 2 3 3 3 0 zinc-ribbon domain TFIIS_C PF01096.13 EMC90802.1 - 0.18 11.4 6.6 8.3 6.1 0.1 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-IS66 PF13005.2 EMC90802.1 - 0.19 11.7 5.3 2.7 8.0 0.1 2.9 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-BED PF02892.10 EMC90802.1 - 0.21 11.3 3.7 1.6 8.5 0.6 2.3 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_4 PF13717.1 EMC90802.1 - 0.3 10.8 8.1 14 5.4 2.7 3.0 2 1 1 3 3 3 0 zinc-ribbon domain YhfH PF14149.1 EMC90802.1 - 0.31 10.8 9.8 3.4 7.5 0.1 3.1 3 0 0 3 3 3 0 YhfH-like protein DZR PF12773.2 EMC90802.1 - 0.32 10.8 7.6 4.2 7.2 5.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon XPA_N PF01286.13 EMC90802.1 - 0.36 10.5 7.0 8.1 6.2 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zf-FCS PF06467.9 EMC90802.1 - 0.51 10.0 6.2 0.69 9.6 1.4 2.2 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.2 EMC90802.1 - 0.51 10.4 3.2 4.8 7.3 1.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_2 PF13240.1 EMC90802.1 - 0.53 9.8 11.9 0.7 9.4 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain RRN7 PF11781.3 EMC90802.1 - 0.72 9.4 3.8 8.9 5.9 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 EMC90802.1 - 0.74 9.7 8.2 5.9 6.8 0.1 2.9 2 1 1 3 3 3 0 IBR domain Fer4_17 PF13534.1 EMC90802.1 - 0.79 10.1 3.9 79 3.7 0.1 2.9 1 1 1 3 3 3 0 4Fe-4S dicluster domain Zn_ribbon_recom PF13408.1 EMC90802.1 - 1 9.7 6.5 25 5.2 2.6 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-UBP PF02148.14 EMC90802.1 - 1.1 9.3 7.1 5.8 7.1 4.0 2.4 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Yippee-Mis18 PF03226.9 EMC90802.1 - 1.3 9.0 5.0 7 6.7 3.5 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.1 EMC90802.1 - 1.6 8.6 11.1 2.6 7.9 0.2 3.0 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_5 PF14634.1 EMC90802.1 - 1.9 8.3 5.5 7.9 6.2 0.7 2.5 1 1 1 2 2 2 0 zinc-RING finger domain C1_4 PF07975.7 EMC90802.1 - 2.1 8.4 7.1 19 5.3 0.1 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain Evr1_Alr PF04777.8 EMC90802.1 - 2.2 8.2 6.3 5.2 7.0 0.8 2.5 1 1 1 2 2 2 0 Erv1 / Alr family GATA PF00320.22 EMC90802.1 - 2.3 7.6 6.2 3.7 6.9 0.1 2.9 3 0 0 3 3 3 0 GATA zinc finger Nudix_N_2 PF14803.1 EMC90802.1 - 2.4 7.9 7.9 47 3.7 0.1 3.3 2 1 0 2 2 2 0 Nudix N-terminal PHD PF00628.24 EMC90802.1 - 2.8 7.7 6.6 5.6 6.7 1.8 2.4 1 1 1 2 2 2 0 PHD-finger ADK_lid PF05191.9 EMC90802.1 - 3.1 7.5 7.1 6.7 6.4 0.1 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid DUF2256 PF10013.4 EMC90802.1 - 3.9 7.3 5.9 14 5.5 0.1 2.6 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_3 PF14369.1 EMC90802.1 - 4 7.5 7.9 5.1 7.1 0.2 2.7 3 0 0 3 3 3 0 zinc-finger zf-ribbon_3 PF13248.1 EMC90802.1 - 5.5 6.3 10.8 3.5 6.9 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EMC90802.1 - 9 5.7 7.8 9.3 5.6 0.2 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zf-H2C2_2 PF13465.1 EMC90803.1 - 2.6e-09 36.8 5.7 5.2e-05 23.3 0.8 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMC90803.1 - 1.7e-05 24.8 2.9 2.5e-05 24.3 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90803.1 - 0.0028 17.8 2.1 0.0039 17.4 1.5 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMC90803.1 - 0.01 15.9 0.2 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EMC90803.1 - 0.013 15.7 1.3 0.024 14.8 0.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-FCS PF06467.9 EMC90803.1 - 0.041 13.5 0.2 0.043 13.4 0.2 1.1 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif LIM PF00412.17 EMC90803.1 - 0.054 13.5 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 LIM domain zf-C2H2_6 PF13912.1 EMC90803.1 - 0.068 13.0 0.7 0.087 12.7 0.5 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.7 EMC90803.1 - 0.1 12.7 0.4 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LSM PF01423.17 EMC90804.1 - 5e-06 25.9 0.0 5.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.3 EMC90804.1 - 0.09 13.1 2.5 0.12 12.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) Keratin PF02422.11 EMC90805.1 - 4.9e-15 55.2 9.4 5.9e-15 55.0 6.5 1.1 1 0 0 1 1 1 1 Keratin Cornifin PF02389.10 EMC90805.1 - 0.0045 16.7 3.4 0.0049 16.6 2.3 1.0 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.3 EMC90805.1 - 0.13 12.3 1.9 0.15 12.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) zf-C2H2 PF00096.21 EMC90806.1 - 6.1e-12 45.1 9.1 1.2e-06 28.5 0.2 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMC90806.1 - 7.8e-11 41.5 9.5 2.1e-05 24.5 0.4 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMC90806.1 - 1.7e-10 40.6 13.7 9.2e-10 38.3 1.6 2.4 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMC90806.1 - 6.9e-09 35.5 4.5 0.00077 19.5 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMC90806.1 - 2.4e-08 33.6 5.1 0.0004 20.1 0.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EMC90806.1 - 5.6e-08 32.7 4.9 0.0011 19.0 1.2 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EMC90806.1 - 0.0021 17.9 1.2 1.5 8.8 0.2 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf-LYAR PF08790.6 EMC90806.1 - 0.0052 16.4 2.6 0.21 11.3 0.0 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger XPA_N PF01286.13 EMC90806.1 - 0.015 14.9 1.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-Di19 PF05605.7 EMC90806.1 - 0.022 14.8 3.1 0.039 14.0 2.1 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMC90806.1 - 0.044 13.8 3.4 0.16 12.1 0.8 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 EMC90806.1 - 0.045 13.3 3.6 0.056 13.0 1.4 1.8 1 1 0 1 1 1 0 GAGA factor zinc-ribbons_6 PF07191.7 EMC90806.1 - 0.048 13.4 2.6 0.78 9.5 1.8 2.0 1 1 0 1 1 1 0 zinc-ribbons C1_4 PF07975.7 EMC90806.1 - 0.067 13.2 1.4 0.13 12.2 1.0 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain Prok-RING_1 PF14446.1 EMC90806.1 - 0.071 12.8 0.4 6.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.2 EMC90806.1 - 0.071 12.9 4.0 0.12 12.1 2.8 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Cytochrom_CIII PF02085.11 EMC90806.1 - 0.17 12.0 1.5 0.18 11.9 1.0 1.1 1 0 0 1 1 1 0 Class III cytochrome C family Vps39_2 PF10367.4 EMC90806.1 - 0.19 11.9 1.6 0.41 10.8 0.1 1.9 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zinc_ribbon_4 PF13717.1 EMC90806.1 - 0.2 11.3 2.7 2.6 7.8 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain LIM PF00412.17 EMC90806.1 - 0.2 11.7 3.1 6.6 6.8 0.1 2.0 1 1 0 1 1 1 0 LIM domain zinc_ribbon_5 PF13719.1 EMC90806.1 - 0.21 11.2 2.9 2 8.0 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.1 EMC90806.1 - 0.24 11.3 2.3 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 CpXC protein ADK_lid PF05191.9 EMC90806.1 - 0.31 10.7 1.5 1.1 8.9 1.1 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-met2 PF12907.2 EMC90806.1 - 0.37 10.8 3.7 3.4 7.7 0.8 2.2 2 0 0 2 2 2 0 Zinc-binding FYVE PF01363.16 EMC90806.1 - 0.4 10.6 5.9 3.1 7.7 1.1 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-BED PF02892.10 EMC90806.1 - 0.63 9.8 3.3 1.2 8.9 1.3 1.9 1 1 1 2 2 2 0 BED zinc finger zf-CHY PF05495.7 EMC90806.1 - 0.64 10.2 4.1 0.92 9.7 0.5 1.7 1 1 0 1 1 1 0 CHY zinc finger Cytochrome_C7 PF14522.1 EMC90806.1 - 0.78 9.4 3.9 0.22 11.1 0.4 1.5 1 1 0 1 1 1 0 Cytochrome c7 Zn_Tnp_IS1 PF03811.8 EMC90806.1 - 0.81 9.2 4.8 2.5 7.6 3.3 1.8 1 1 0 1 1 1 0 InsA N-terminal domain zf-AN1 PF01428.11 EMC90806.1 - 1.7 8.5 6.6 10 6.0 1.4 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Keratin PF02422.11 EMC90807.1 - 1.7e-22 79.1 4.9 1.8e-22 79.0 3.4 1.0 1 0 0 1 1 1 1 Keratin